Diagnosed with shingles; xperiencing fatigue; Rash developed on back of upper left leg; Felt very tight and stiff; Left leg started bothering; pain from buttock to the ankle; This case was initially received via an unknown source (no reference has been entered for a health authority or license partner) on 26-May-2021. The most recent information was received on 21-Jun-2021 and was forwarded to Moderna on 21-Jun-2021.    This spontaneous case was reported by a non-health professional and describes the occurrence of HERPES ZOSTER (Diagnosed with shingles), MUSCULOSKELETAL STIFFNESS (Felt very tight and stiff), LIMB DISCOMFORT (Left leg started bothering), PAIN (pain from buttock to the ankle) and RASH (Rash developed on back of upper left leg) in a 49-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 022CZ1A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Pneumonia (Age 8) in 1979. Concurrent medical conditions included Heart murmur (Benign, Not specified) since 2008. Concomitant products included ASCORBIC ACID, MULTIVITAMINS [VITAMINS NOS] and VITAMIN D3 for an unknown indication.   On 16-May-2021 at 10:45 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 17-May-2021 at 8:00 AM, the patient experienced MUSCULOSKELETAL STIFFNESS (Felt very tight and stiff), LIMB DISCOMFORT (Left leg started bothering) and PAIN (pain from buttock to the ankle). On 18-May-2021, the patient experienced RASH (Rash developed on back of upper left leg). On 20-May-2021, the patient experienced HERPES ZOSTER (Diagnosed with shingles). 20-May-2021, the patient experienced FATIGUE (xperiencing fatigue). The patient was treated with GABAPENTIN for Painful rash, at a dose of 1 dosage form; VALACICLOVIR HYDROCHLORIDE (VALTREX) for Herpes zoster, at a dose of 1 dosage form and BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE (NEOSPORIN TOPICAL) (topical) on 18-May-2021 for Rash, at a dose of 1 dosage form. At the time of the report, HERPES ZOSTER (Diagnosed with shingles), LIMB DISCOMFORT (Left leg started bothering), PAIN (pain from buttock to the ankle), RASH (Rash developed on back of upper left leg) and FATIGUE (xperiencing fatigue) had not resolved and MUSCULOSKELETAL STIFFNESS (Felt very tight and stiff) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 20-May-2021, Blood pressure measurement: 125/80. On 20-May-2021, Body temperature (97.7-99.5): 98.6. On 20-May-2021, Heart rate: 72.   The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   The patient had no symptoms on the day of vaccination. These events began the next day after the shot on 18-May-2021. He later consulted the doctor on 20-May-2021 and  was diagnosed with shingles but was uncertain whether the event was related to the vaccine or not despite his doctor reassurance. On the Vaers follow-up form received by 21-Jun-2021 the patient did relate these events to the vaccine.   Treatment information included the use of topical antibiotic ointment, antiviral drug and gabapentin but had no effect on patient. Patient reported that the rash had persisted after 5 weeks after the shot.   Most recent FOLLOW-UP information incorporated above includes: On 21-Jun-2021: Significant updates on Patient tab, Product tab, Events, Outcome, and Narrative On 21-Jun-2021: No significant information. On 26-Jul-2021: Secondary Reporter information added