inflammatory polyneuropathy with sensory neuropathyin both legs minor motor deficits (comments: worsening neuropathy/carpal tunnel in both hands despite decrease in activity and regular arm bracing); inflammatory polyneuropathy with sensory neuropathyin both legs minor motor deficits (comments: worsening neuropathy/carpal tunnel in both hands despite decrease in activity and regular arm bracing); Possible myelitis in thoracic; Condition aggravated; peroneal palsy (comment: carpal tunnel in both hands prior injury, symptoms worsened significantly after vaccination); peroneal palsy (comment: carpal tunnel in both hands prior injury, symptoms worsened significantly after vaccination); This is a spontaneous report received from a contactable reporter (Consumer or other non-HCP). The reporter is the patient.  A 49-year-old female patient received BNT162b2 (BNT162B2), on 30Mar2021 at 14:40 as dose 2, single (Lot number: EN6208) at the age of 49 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Epilepsy" (ongoing), notes: Diagnosed almost 5 years earlier; "Seizures" (unspecified if ongoing); "Carpal tunnel in both hands prior injury" (unspecified if ongoing), notes: Carpal tunnel in both hands prior injury; "Carpal tunnel in both hands" (unspecified if ongoing). Concomitant medication included: VIMPAT oral taken for seizure, start date: Sep2020, stop date: 21Sep2021. Vaccination history included: BNT162b2 (Dose: 1st, Date: 09Mar2021, Time: 03:30 PM, Anatomical Site of injection: Left arm, upper, Route of administration: Intramuscular, Batch/Lot number: EN6198), administration date: 09Mar2021, when the patient was 49-year-old, for COVID-19 Immunization, reactions: "transverse myelitis", "Guillain Barre resulting in myeltitis small fiber and sensory neuropathy with sensory involvement with mitochondiral disease", "Sensory neuropathy", "Small fiber neuropathy", "cheeks felt warm", "rash on her neck and cheeks", "numbness in her feet, especially the left foot/ It is affecting her entire body, face, tongue, and mouth", "transient mouth/tongue tingling", "fasciculations", "mouth burning". The following information was reported: CONDITION AGGRAVATED (medically significant) with onset May2021, outcome "unknown"; PERONEAL NERVE PALSY (non-serious), CARPAL TUNNEL SYNDROME (non-serious) all with onset May2021, outcome "unknown" and all described as "peroneal palsy (comment: carpal tunnel in both hands prior injury, symptoms worsened significantly after vaccination)"; MYELITIS (medically significant) with onset Jul2021, outcome "unknown", described as "Possible myelitis in thoracic"; POLYNEUROPATHY (medically significant), PERIPHERAL SENSORY NEUROPATHY (non-serious) all with onset Nov2021, outcome "unknown" and all described as "inflammatory polyneuropathy with sensory neuropathyin both legs minor motor deficits (comments: worsening neuropathy/carpal tunnel in both hands despite decrease in activity and regular arm bracing)". The patient underwent the following laboratory tests and procedures: Magnetic resonance imaging head: (May2020) Possible myelitis in thoracic; (Jul2021) Possible myelitis in thoracic; Nerve conduction studies: (May2021) Peroneal palsy, notes: Carpal tunnel in both hands prior injury. symptoms worsened significantly after vaccination; (Nov2021) Inflammatory polyneuropathy with sensory neuropath, notes: Worsening neuropathy carpal tunnel in both hands despite decrease in activity and regular arm bracing.  Follow-up attempts are completed. No further information is expected.