Rhinovirus came back on the viral panel; The hives have migrated coming and going and severely itching; Broke out in a severe rash like hives all over her body/hives all over face, feet and palms; Exposure via breast milk; This spontaneous case was reported by a consumer and describes the occurrence of RHINOVIRUS INFECTION (Rhinovirus came back on the viral panel), PRURITUS (The hives have migrated coming and going and severely itching), URTICARIA (Broke out in a severe rash like hives all over her body/hives all over face, feet and palms) and MATERNAL EXPOSURE DURING BREAST FEEDING (Exposure via breast milk) in a 24-year-old female patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. ASKU) for COVID-19 prophylaxis.     Skin was super sensitive to things and patient would react to a rash. No food allergies. Been on allergy medication her whole life singular and nasal spray.  The patient's past medical history included Hives, Contact dermatitis and Sensitive skin. Previously administered products included for COVID-19 prophylaxis: Spikevax and Spikevax; for Product used for unknown indication: MENACTRA (4 years ago), PREDNISOLON [PREDNISOLONE SODIUM PHOSPHATE] (4 years ago) and Influenza. Past adverse reactions to the above products included Adverse reaction with MENACTRA and PREDNISOLON [PREDNISOLONE SODIUM PHOSPHATE]; and No adverse event with Influenza, Spikevax and Spikevax. Concurrent medical conditions included Seasonal allergy.    On 13-Dec-2022, the patient received third dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. On 23-Dec-2022, the patient experienced RHINOVIRUS INFECTION (Rhinovirus came back on the viral panel), PRURITUS (The hives have migrated coming and going and severely itching), URTICARIA (Broke out in a severe rash like hives all over her body/hives all over face, feet and palms) and MATERNAL EXPOSURE DURING BREAST FEEDING (Exposure via breast milk). The patient was treated with CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) at an unspecified dose and frequency. On 23-Dec-2022, MATERNAL EXPOSURE DURING BREAST FEEDING (Exposure via breast milk) had resolved. At the time of the report, RHINOVIRUS INFECTION (Rhinovirus came back on the viral panel), PRURITUS (The hives have migrated coming and going and severely itching) and URTICARIA (Broke out in a severe rash like hives all over her body/hives all over face, feet and palms) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 28-Dec-2022, Respiratory viral panel: Rhinovirus came back on the viral panel.     For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Unknown), the reporter did not provide any causality assessments.   Concomitant medications were not reported.  Patient received Spikevax on 13-Dec-2022 and 10 days later broke out in a severe rash like hives all over body. The hives had migrated coming and going and severely itching. Patient was experiencing it at the time of reporting. Patient took Zyrtec but it kept getting more severe. Patient went to the doctor yesterday morning and ran a viral panel and gave her a steroid shot and told patient in 23 hours it should be helpful, but it was not. Doctor told patient to continue with the Zyrtec. Patient experienced the hives all over face, feet and palms. Patient received 2 primary series doses and 1 booster dose from Moderna but did not have vaccination card to provide details. Patient got a puppy recently and that was the only other new thing that come up but she was not normally allergic to dogs.