MILD HEADACHE; TIREDNESS; MUSCLES JERKED (ARMS OR HEAD FLINCHED) WHEN TRIED TO SLEEP; MUSCLE TWITCHING ON BOTH SIDES OF BODY (CALFS, THIGHS, NECK, HANDS); HAND SHAKED LIKE ESSENTIAL TREMOR; GOT ZERO HOURS OF SLEEP; FELT JITTERY; FEELING OF CRAMP IN BOTH CALFS; SHAKING IN HEAD, LEGS AND OTHER PLACES TOO (LIKE A CONSTANT CHILL); JOINT PAIN IN FOREARMS, WRISTS AND FINGERS OF BOTH SIDES; FELT FATIGUE MORE THAN NORMAL IN LEGS, PARTICULARLY IN CALFS AFTER RUNNING; MILD HEADACHE; TIREDNESS; This spontaneous report received from a patient via other manufacturer (Pfizer) concerned a 51 year old male with unspecified race and ethnic origin. The patient's height, and weight were not reported. Patient had a healthy family history and had no medical issues. Patient ran 20 miles per week and had very good annual physical results. The patient received covid-19 vaccine ad26.cov2.s (dose number in series 1) (suspension for injection, intramuscular, batch number: 1808980, expiry: unknown) dose was not reported, 1 total administered to top left arm on 31-MAR-2021 for prophylactic vaccination. No concomitant medications were reported. On an unspecified date after the first shot of J&J, the patient experienced mild headache and tiredness for about 24 hours and then had no issues (dose number in series 1). The action taken with covid-19 vaccine ad26.cov2.s was not applicable.  The patient recovered from mild headache, and tiredness. The patient received non-company booster BNT 162 (Pfizer) vaccine (dose number in series 2) (form of admin was not reported, intramuscular, batch number: FH8028, expiry: unknown) dose was not reported, 1 total administered to top left arm on 09-NOV-2021 at 13:00 hours for prophylactic vaccination. No concomitant medications were reported. In NOV-2021, the patient had mild headache and tiredness for 24 hours so it all seemed fine but then after 5 or 6 days after receiving Pfizer shot, Patient had weird symptoms that had started to appear. First symptom was muscle jerks he when tried to sleep (arms or head would flinch so much, it made him wake up so basically and had zero hours of sleep). The following days the muscle jerks reduced but in their place was muscle twitching on both sides of body especially at rest (calfs, thighs, neck, hands). Patient also felt like he was connected to a battery of something. Patient also felt jittery. His entire body was like this could hold hands out in front and they would shake like a essential tremor. He felt like shaking in head, legs and other places too (almost like a constant chill). This continued for about 5 weeks, reducing slightly in intensity. The next symptom was the feeling of cramp in both calfs, it felt like he always needed to stretch them. Patient also noticed that after running, he felt more fatigue than normal in the legs, particularly in calfs. Patient's final symptom was joint pain, especially in forearms, wrists and fingers of both sides. Eight weeks after Pfizer shot, Patient had some symptoms they have reduced in intensity by at least 75 percent at the time of reporting. Internal tremor was very light and hands barely shaked then and joints were not as rigid and muscle twitching was minimal when patient went to sleep. Laboratory data (dates unspecified) included: Blood urine (NR: not provided) very good, and Physical examination (NR: not provided) very good. The action taken with bnt 162 was not applicable. The patient recovered from mild headache, and tiredness, and was recovering from muscles jerked (arms or head flinched) when tried to sleep, muscle twitching on both sides of body (calfs, thighs, neck, hands), felt jittery, hand shaked like essential tremor, shaking in head, legs and other places too (like a constant chill), feeling of cramp in both calfs, felt fatigue more than normal in legs, particularly in calfs after running, joint pain in forearms, wrists and fingers of both sides, got zero hours of sleep, mild headache, and tiredness.  This report was non-serious.