aches and pains; weak spot including electrical shots in her neck and back; injection site looked like she was hit with a baseball as it was raised and itchy; red; injection site looked like she was hit with a baseball as it was raised/swollen; injection site looked like she was hit with a baseball as it was raised and itchy and hot to the touch.; hit by a baseball; pain in her neck; shivering/chills; shaking; This case was reported by a consumer via call center representative and described the occurrence of shivering in a 54-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included fever. Previously administered products included Flu vaccine (Doses receeived on an uknown date.). Concurrent medical conditions included allergic reaction to wasp sting, asthma and chemical allergies (refer case id US2020AMR197140). Concomitant products included Herpes zoster (Shingrix) and prednisone.   On 25th September 2020, the patient received the 2nd dose of Shingrix (intramuscular). On 26th September 2020, 1 days after receiving Shingrix and an unknown time after receiving Shingrix, the patient experienced shivering and tremor. On an unknown date, the patient experienced pain, electric shock sensation, injection site itching, injection site erythema, injection site swelling, injection site warmth, injection site pain and neck pain. The patient was treated with hydrocortisone (Cortisone Topical Cream). On an unknown date, the outcome of the shivering, tremor, electric shock sensation, injection site swelling and injection site pain were recovered/resolved and the outcome of the pain, injection site erythema, injection site warmth and neck pain were unknown and the outcome of the injection site itching was not recovered/not resolved.   It was unknown if the reporter considered the shivering, tremor, pain, electric shock sensation, injection site itching, injection site erythema, injection site swelling, injection site warmth, injection site pain and neck pain to be related to Shingrix.  Additional information as follows: The patient received the 2nd dose of Shingrix and experienced shivering, tremor, pain, electric shock sensation, injection site itching, injection site erythema, injection site swelling, injection site warmth and neck pain, which is not resolved. The patient reported that she received the second shot of Shingrix on 25th september 2020 after getting the first shot on 23rd july 2020. After getting the second dose on Friday, 25th september 2020, in her left arm IM, she awoke Saturday morning at 4:30am and had shivering, shaking and chills. The patient had aches and pains everywhere that lasted 10-12 hours. The pain traveled everywhere on her body that she has a weak spot including electrical shots in her neck and back which have resolved but every now and then she will still have pain in her neck. The injection site looked like she was hit with a baseball as it was raised and itchy and hot to the touch. The patient used topical cortisone cream on the injection site and it is much better now but still itchy. The patient informed that it was red and swollen but the area is shrinking in size. She met with a tele doctor last evening who prescribed a steroid pack for her but she did not started treatment yet. She is wondering if her wasp sting and the bad reaction she experienced played a part in her recent experience with the Shingrix vaccine. The patient had history of chemical allergies and asthma.  The patient also reported that she gets the flu vaccine and several times, but not every time, she will experience a fever that resolves. The reporter consented to follow up. No further information was available. This case was linked with case id US2020AMR197140 and US2020AMR197139 reported by same reporter.; Sender's Comments:  US-GLAXOSMITHKLINE-US2020AMR197140:same patient Shingrix 2nd dose