Diarrhea; Left cheek was all red, my arms were red and the bottom of my legs, now usually the bottom of my leg that happens because I have lymphedema in my leg but the bottom of my leg are swollen; Left cheek was all red, my arms were red and the bottom of my legs, now usually the bottom of my leg that happens because I have lymphedema in my leg but the bottom of my leg are swollen; now usually the bottom of my leg that happens because I have lymphedema in my leg but the bottom of my leg are swollen; Hand aren't cold; During the night I had the chills, I was burning; During the night I had the chills, I was burning; Could only sleep for an hour, so wake up an hour or so and wake up; Rash and that was very itchy; Rash and that was very itchy; Very tired and mushy mush; Felt very lethargic; Very tired and mushy mush; Felt very lethargic; Arm hurt and it hurt up to my neck; Arm bothered me and it went in to my neck; Arm hurt and it hurt up to my neck; Arm bothered me and it went in to my neck; This is a spontaneous report received from a contactable consumer (Patient).  A 73-year-old female patient received first dose of bnt162b2(PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection), via an unspecified route of administration on 25May2021 at noon time (Batch/Lot Number: EW0183) as 1st dose, single dose for covid-19 immunization.Medical history included hypertension, ongoing diabetes mellitus and atrial fibrillation. Concomitant medications included metformin (METFORMIN) 500 mg, 2x/day taken for diabetes mellitus, metoprolol succinate (TOPROL XL) 100 mg, 2 Tablets in Morning and 2 Tablets at night, diltiazem (DILTIAZEM) 180 mg, 2x/day, furosemide (FUROSEMID) 40 mg, 1x/day, losartan (LOSARTAN) 50 mg, 1x/day, 1 tablet a day, atorvastatin calcium (LIPITROL [ATORVASTATIN CALCIUM]) 20 mg, 1x/day, ergocalciferol (VIT D) 1000, 2x/day, blood thinner :dabigatran etexilate mesilate (PRADAXA) 150 mg, 2x/day and nitrofurantoin (NITROFURANTOIN) 100 mg, 1x/day for 10 days. On 25may2021, the patient received the Pfizer shot and was fine all day on tuesday and on 26May2021 (Wednesday) patient was like very tired and mushy mush, her arm hurt and it hurt up to my neck, so she took it easy all day Wednesday and got up Thursday fine. On 27May2021 and 28May2021, the patient was perfectly fine and then when she went to bed last, well other than that she had that rash going on and actually she should say that she had the rash and that was very itchy and that was thursday and fridays and the cream that she had taken by doctor had given her a while back she used that and that subsided the itching. The patient got up friday fine and last night on 28May2021, during the night patient had the chills, she was burning. The patient do have and do had a rash but it's a rash that had gotten before and used the medicine that that doctor had given her and it had taken it, it had cleared it away, so she know on the directions here it says about a rash. And so when she got up this morning on 29May2021, she have some diarrhea and when got up this morning actually she got up during the night and was like maybe it's my diabetes. So patient had some orange juice in water and went back to bed but she could only sleep for an hour, so wake up an hour or so and wake up. When patient got up this morning i.e on 29May2021, the left cheek was all red, my arms were red and the bottom of my legs, now usually the bottom of my leg that happens because patient have lymphedema in her leg but the bottom of her leg are swollen. So now as the morning has gone on things are subsiding her hand aren't cold anymore and she was feeling better. The patient reported, that was Clotrim/ Beta CRE Diprop and that's topically applied twice a day but she have only done it once a day on the last 2 days, Thursday and Friday (further clarification unknown) and also she told that on 28May2021 was her last day on 10 days of antibiotic, that's Nitrofurantoin and that's a 100 mg and that was one a day, no twice a day for 10 days and yesterday was the 10th day.The outcome of events insomnia, diarrhea , burning sensation , chills ,temperature regulation disorder, peripheral swelling, lymphoedema, erythema was resolving and outcome of rash, neck pain , pain in extremity (arm), lethargy , fatigue, pruritus was resolved in may2021