This is a spontaneous report from a contactable consumer (patient's daughter). This consumer reported similar events for three patients. This is the first of three reports. A 71-year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: EN6202), via an unspecified route of administration, administered in left arm on 01Mar2021 (at 71-year-old) as dose 2, single for COVID-19 immunization. Medical history included that he had the cholesterol of a twenty year old, the month prior to getting the second vaccine, he had a yearly work up of his heart and cholesterol and all that, they put a heart monitor on him to be sure everything was fine with that, and he had gotten a clean bill of health. He had never had any sort of medical situation or even surgeries until two years ago (2019), when he had a knee replacement, and he had a history of shingles, he got about fifteen years ago (2006) and they never really went away, so he's had on and off for the past fifteen years. The patient's concomitant medications were not reported. The patient previously received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: EL9267), via an unspecified route of administration, administered in left arm on 10Feb2021 (at 71-year-old) as dose 1, single for COVID-19 immunisation. The patient had two strokes on 19Mar2021 (reported as eighteen days after his second vaccine) and has been in the hospital ever since. He has developed anemia, he had muscle atrophy, and he was experiencing persistent fevers. He said that its like his blood was fighting/contradicting himself and they were pretty sure that it was from the vaccine. He already had 1 blood transfusions and his white blood cells were low and his ANC (absolute neutrophil count) was normal. Caller said nothing medically makes sense. She said it's like the vaccine changed the protein in the blood. The patient has had test after test after test, has had strokes in the medulla cerebellum, his hemoglobin won't stay above seven, he's had multiple blood transfusions, with signs of inflammation and infectious disease, but nothing in his body told them. No scans, blood tests, surgery, biopsies, ultrasound, he's literally had every test. Caller added patient was dying, and they didn't know why. He remained hospital from 23Mar2021 until he went home on 15Apr2021. While in rehab, patient started developing fever of unknown origin, that they can't figure out. On 25Apr2021, the patient went to the emergency room. He was home ten days and was declining that whole time, with fever up and down, lost cognition, really confused, which they thought was a result of stroke, but he was declining rapidly. He had fell a bunch, started losing muscle, muscle started atrophying at that point. When they took him in on the 25Apr2021, it's because his blood pressure dropped, another issue that started all of this, he could not maintain his blood pressure, if he sat up and moved, it would drop. And that day when he tried to stand and it dropped and he slid down. They took him to the emergency room and he had a potassium deficiency and they gave him potassium. He went home that day after the potassium. Then on 27Apr2021, he went back to hospital, into their emergency room, and spent a couple days in the ER, but was admitted into a room once available and stayed until 15May2021, when they transferred him from there. He remained here from 15May2021 to 21May2021. They were wanting to transfer him to another hospital. The outcome of the events was unknown.  No follow-up attempts are possible. No further information is expected.