Thought it was dipoplia; Having issues with eyes, seeing spots; Wifes migraines have been getting worse; vision changes/started to see spots and blue lines; optical migraines; She can't drive or go on the computer; dry eyes; started seeing flashes if she looked at anything (began within seconds, would start seeing negative picture form to side of object), then would go away; This is a spontaneous report from a contactable consumer or other non-healthcare professional via Medical Information Team. A 54-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot number: EW0176), via an unspecified route of administration on 18May2021 as dose 2, single for COVID-19 immunisation. Medical history included migraine, dry eye from 2011 to an unknown date. Prior vaccine: flu shot on unspecified date and unspecified month in 2020, for immunization. There were no concomitant medications. Historical vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution or injection; Expiry Date: unknown, Lot number: EWO169), via an unspecified route of administration on 27Apr2021 administered in left arm as dose 1, single for COVID-19 immunisation and experienced events. She has had migraines since she was 10 or 12 years old. It has been mild in the past. In the last two months to a month it has been more frequent, dry eye from 2011 to an unknown date, from an unknown date and unknown if ongoing. The patient experienced vision changes/started to see spots and blue lines, having issues with eyes, seeing spots on, migraines have been getting worse, optical migraines, she cant drive or go on the computer, dry eyes, started seeing flashes if she looked at anything (began within seconds, would start seeing negative picture form to side of object), then would go away, thought it was dipoplia on Jun2021. Wondered if vision changes are related to vaccine. The doctor was also saying she may be having optical migraines. Has taken his wife to eye doc tor 3-4 times, and they say other than dry eyes, there is nothing wrong with eyes or optic nerve. States these are not her typical migraines.  Reports this is happening a lot.  When she goes outside without too much visual stimulus, not as bad.  Worse indoors.  Doesn't behave like her regular migraines, which Excedrin used to help.  Flashing spots are getting bigger and not going away. Caller's wife mentioned what she was going through.  Eye doctor said he can't get into specifics, but he knows of people that are experiencing blurred visions, fuzzy visions, and eyes not working properly.  Said it was temporary, but no time frame given. Caller expresses his frustration with not getting answers from HCPs or anyone else. Caller stated the severity of his wifes symptoms are causing a lot of distress.  He states that he feels like they're in a circle where they get no answers, told to go to doc or ER, but they still don't know where this is coming from. She went to get an eye exam. She went for her eyes a month or so before in February and the doctor wanted to give her eye drops to use. She did the eye exam for one eye and then she went to the eye doctor in May after the first shot and she started to see spots and blue lines. The doctor looked but there was nothing wrong with her eyes. His wife suffers from dry eyes for over 10 years they have given her different eye drops. Patient went to Emergency Room to (withheld) they said it sounds like an optical migraine. Wanted to confirm it was not a tumor. Patient Went to the eye doctor and said nothing wrong with her eye. Nothing wrong but the same symptoms. They saw her optic nerve, and nothing was wrong with that. They set her up to see a neuro doctor they thought it was something in her head and they had to look at the report. She saw the neuro doctor this past Monday and is seeing lights. In 30 minutes, they would get better and for 24 hours a day and 7 days a week she has no migraine. She went to the ER, they told her nothing then she went back to the doctor, and they thought it was dipoplia. They asked the eye doctor. They said people in her age get that and in this time of year it could also be MS. After the doctor had said optical migraines. They asked if it could be the Pfizer causing the side effects. They haven't heard of anything and they just don't know. And today she is still having vision problems and it's worse and she is seeing different sites and not seeing with her eyes. She can't stand to get on the computer or drive. Caller stated I took her to the emergency room because she felt she is having a migraine (Clarification unknown). I took her to the migraine doctor they said there is nothing (incomplete sentence), they did an MRI and said there's no tumor, there is nothing in her head and she had been to that eye doctor three times and each time there is nothing wrong with your eye, there nothing wrong with your optic nerve there something that is causing these vision changes and they are getting worse." Reporter further added, "I did not have words to turn because every doctor we go to and we tell them that she had the shot and she's experiencing these problems, they keep telling her we haven't had no side effects that is this, just go have your eyes looked as well, we go to eye doctor he says I have never heard of these side effects, you might need to see neurologist, well we go to neurologist they say we haven't heard of any of these side effects, you might want to check your primary doctor, she goes to primary doctor and they say well we haven't seen any side effects on this, you might want to go and have your eyes checked, so everybody saying to go another doctor and another doctor. She has been round and round twice, and she went to this one family doctor where we live, and she says yes, I have heard of these side effects and I have seen them up here (Further clarification was unknown). We need to find out if possible are they going to be temporary issue and everything should clear up within a few weeks, are they permanent or they going to worse or what. Therapeutic measures were taken as a result of having issues with eyes, seeing spots, migraines have been getting worse, vision changes/started to see spots and blue lines, optical migraines, she can't drive or go on the, dry eyes, started seeing flashes if she looked at anything (began within seconds, would start seeing negative picture form to side of object), then would go away, thought it was dipoplia. The patient underwent lab tests and procedures which included magnetic resonance imaging: normal   on 2021 (MRI done to check for MS, which was negative. MRI "normal"), ophthalmological examination: nothing wrong with her eyes on May2021, ophthalmological examination: unknown on 2021 (She did the eye exam for one eye), ophthalmological examination: unknown on 30Jun2021.  The outcome of event vision changes/started to see spots and blue lines and event started seeing flashes if she looked at anything (began within seconds, would start seeing negative picture form to side of object), then would go away was not recovered and for rest all event outcome was unknown.