pain started in her shoulder where she got the shot; muscle pain; muscle atrophy/ it is hard like muscle atrophy; Intense muscle spasm; then spread to her other shoulder and her entire back and the muscle in the back of her thigh; then spread to her other shoulder and her entire back and the muscle in the back of her thigh; then spread to her other shoulder and her entire back and the muscle in the back of her thigh; muscle on the back of her thigh sticks out; pain throughout her body; cannot stand up straight and has to crawl out of bed due to the pain; This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 63-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Previous severe reaction to Crestor medication with an associated reaction of myalgia (had experienced similar but severe reaction).   On 26th August 2019, the patient received the 1st dose of Shingrix (intramuscular). On 29th August 2019, 3 days after receiving Shingrix, the patient experienced injection site pain, muscle pain, muscle atrophy, muscle spasm, shoulder pain, back pain, pain on lower thigh, muscle stiffness, general body pain and difficulty in standing. The patient was treated with trolamine salicylate (Aspercreme), paracetamol (Tylenol) and ibuprofen (Advil). On an unknown date, the outcome of the injection site pain, muscle pain, muscle atrophy, muscle spasm, shoulder pain, back pain, pain on lower thigh, muscle stiffness, general body pain and difficulty in standing were not recovered/not resolved.   It was unknown if the reporter considered the injection site pain, muscle pain, muscle atrophy, muscle spasm, shoulder pain, back pain, pain on lower thigh, muscle stiffness, general body pain and difficulty in standing to be related to Shingrix.  Additional case details were provided as follows: The patient had Shingrix in her left arm. The patient experienced intense muscle spasms and pain throughout her body.  She reported that, 3 days after vaccination, the pain started in her shoulder where she got the shot. It then spread to her other shoulder and her entire back and the muscle in the back of her thigh. She claimed that, the muscle was worst on her left side of her thigh and it was so bad that she could not sit on the toilet. She further stated, the muscle on the back of her thigh stuck out and it was hard like it was muscle atrophy. She could not stand up straight and she had to crawl out of bed due to the pain.  She had to put Aspercream on her entire body. She had been treating the condition with two Tylenol and three Advair just so that she could get out of bed. The patient also mentioned that, she would not be getting another shot and she understood why people took their lives after this experience. The patient could not seek treatment due to a high insurance deductible and no automobile to take her to a physician. The patient consented to follow up and provided her physician's details. The call center representative added that, they contacted the local police department requesting a wellness check after the call disconnected because the patient stated that "it just did not matter anymore" at the end of their phone conversation.