brain damage; my lower arm now begins to swell and then my hand swells; my whole arm was stiff; I bathed the dog and my chest swell, giving me a hard time breathing, specially in the evening as my symptoms get with my disease.; I bathed the dog and my chest swell, giving me a hard time breathing, specially in the evening as my symptoms get with my disease.; Swelling at the injection site; This is a spontaneous report from a contactable consumer (patient).  A 50-year-old female patient received bnt162b2 (COMIRNATY), dose 1 intramuscular on Sep2021 (Batch/Lot number was not reported, NDC number: 59267-1000-01) as single dose (at the age of 50-years-old) for COVID-19 immunization. Medical history included COP disease. Concomitant medications included tramadol, tapentadol hydrochloride (NUCYNTA), gabapentin, alprazolam, lisinopril, levothyroxine sodium (SYNTHROID), hydroxyzine. No prior vaccinations (within 4 weeks). The patient experienced brain damage on an unspecified date, swelling at the injection site on Sep2021, "my lower arm now begins to swell and then my hand swells" on Sep2021, "my whole arm was stiff" on Sep2021, "I bathed the dog and my chest swell, giving me a hard time breathing, specially in the evening as my symptoms get with my disease" on Sep2021. The patient stated, "I had my first vaccine 43 days ago, today is the 43rd day and I knew that I could wait 21 to 42 days so I was kindly doing that because I had an immediate reaction not a severe reaction but an immediate one with my first vaccine at a clinic. They gave me the shot and I stood up and took two steps and right away was going on and I have COP disease (further not clarified) which is an extremely rare and incurable disease and I am not like much people. Out of 200 thousand, I have that disease. I am one percent of those, I have full body, so upper and lower extremities have COP on it. So, it's already diseased. But it did not really seem to affect me too much in the store the other day, I had a lot of swelling afterwards and of course I went into a flare because of the injection but I have those that happens to me. But the day I had those injections injection, like I said, I stood up and took two steps, it was swelling at the injection site already noticed and then soon to follow my lower arm, so step up in the injection site my lower arm now begins to swell and then my hand swells and my whole arm was stiff and it was for about two days. So, the original pharmacy has turned me down, saying they have never seen such a reaction or occurred a reaction like that. So, they are uncomfortable with giving me the second vaccine and then they said they had a stand-in pharmacy coming in for a day and they will surely give it to me. Now, they turned me down today too. Actually, two pharmacists turned me down today. They said that if I started to swell or had trouble breathing or notice any signs of that, they don't have a bed, they could lay me down and they don't have anyone who can keep an eye on me and because they are so busy with their job and I do, one of the promise of my disease, one of the most that I have is I swell all over and even this past week my chest has been swollen because I bathed the dog, that is all I did. But I bathed the dog and my chest swell, giving me a hard time breathing, specially in the evening as my symptoms get with my disease. I am just trying to figure out if this reaction is further, is it safe for me to get? I just got to find somebody. There is no way to get a bed and a vaccine shot in my area, the places that operate are just like that and I had Epipens, but they are expired. My mom is going to write it down for me, she helps me because I have some brain damage from this disease so she is going to help me." No lab tests. Therapeutic measures were taken as a result of the events which included Benadryl. The outcome of the events was unknown.  The lot number for the vaccine, BNT162B2, was not provided and will be requested during follow-up.