Bad reaction/response to rabies vaccine; Case reference number US-BN-2023-000098 is a spontaneous case report initially received on 18-Jan-2023 via Manufacturer and concerns a female patient of unknown age.  The patient's relevant medical history and concomitant medication details were not provided.   On an unspecified date, the patient was vaccinated with a dose of rabies vaccine (brand name: unknown; batch number: not provided), at an unknown dose, site or route of administration for unknown indication.   On an unspecified date, an unknown amount of time after the vaccination with the rabies vaccine, the patient experienced a bad reaction (response) to vaccination (to be clarified).  On an unspecified date, an unknown amount of time after the vaccination with rabies vaccine, the patient was vaccinated with the first dose of co-suspect Shingrix (batch number: not provided), and only 0.5 ml was injected, not 2 ml of dose, at an unknown route or site of administration, for an unknown indication. As reported, the patient experienced unspecified symptoms and the symptoms were resolved. As also reported, the patient would not be getting the second dose of Shingrix.  On an unspecified date, an unknown amount of time after the vaccination with the rabies vaccine, the patient went to the doctor's office to get a routine blood draw and white blood cell (WBC) count was, as reported ''out of whack'', both high and low. As reported, the patient attributed that to the Shingrix shot and that the patient could not remember exactly, but believed eosinophils and lymphocytes were high, but neutrophils were low.  At the time of the initial report, the outcome of the event of 'immunization reaction', was unknown.   The reporter did not provide a seriousness or causality assessment for the event of 'immunization reaction'.   Additional information received from Manufacturer on 19-Jan-2023 included confirmation of the primary reporter and country of occurrence.; Reporter's Comments: A female patient of unknown age experienced a non-serious event of bad reaction (response) to vaccination on an unspecified date, an unknown amount of time after the patient was vaccinated with a dose of rabies vaccine, at an unknown dose, site or route of administration for unknown indication. The event of immunisation reaction is considered as listed per company convention. The patient's relevant medical history and concomitant medication details were not provided. The outcome of the event was unknown. Since the contributory role of the suspect vaccine cannot be excluded with certainty, the event of immunisation reaction has been considered as related to rabies vaccine. This case is considered as non-serious.; Sender's Comments: A female patient of unknown age experienced a non-serious event of bad reaction (response) to vaccination on an unspecified date, an unknown amount of time after the patient was vaccinated with a dose of rabies vaccine, at an unknown dose, site or route of administration for unknown indication. The event of immunisation reaction is considered as listed per company convention. The patient's relevant medical history and concomitant medication details were not provided. The outcome of the event was unknown. Since the contributory role of the suspect vaccine cannot be excluded with certainty, the event of immunisation reaction has been considered as related to rabies vaccine. This case is considered as non-serious.