HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE; HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE; SICK; PAIN; HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE; HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE; This spontaneous case was reported by a consumer and describes the occurrence of LETHARGY (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), DECREASED APPETITE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), ILLNESS (SICK), PAIN (PAIN) and FATIGUE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE) in a 63-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.   Co-suspect product included non-company product UPADACITINIB (RINVOQ) tablet for Rheumatoid arthritis.    The patient's past medical history included Umbilical hernia, Hip replacement in 2005 and Knee replacement in 2005. Concurrent medical conditions included Fingernail discoloration since 2005, Dry skin since 2005, Drug allergy (Toradol allergy manifested by anaphylactic shock and hive), Penicillin allergy (manifested by anaphylactic shock and hive), Non-tobacco user and Abstains from alcohol. Concomitant products included LISINOPRIL for Blood pressure high, MELOXICAM (MOBIC) for an unknown indication.   In December 2020, the patient started UPADACITINIB (RINVOQ) (Oral) 15 milligram. In March 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In March 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. In March 2021, the patient experienced LETHARGY (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), DECREASED APPETITE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), ILLNESS (SICK), PAIN (PAIN), FATIGUE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE) and NAUSEA (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE). In March 2021, LETHARGY (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), DECREASED APPETITE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE), ILLNESS (SICK), PAIN (PAIN), FATIGUE (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE) and NAUSEA (HAD COVID VACCINE REACTIONS LETHARGIC/NAUSEA/FATIGUE/LOSS OF APPETITE) had resolved.            Patient stated that bad finger nails and dry skin was started since childhood or all his life and pain. He had been trying for the last two weeks to get hold of the pharmacy solutions but he was having trouble to get through for his medications to get refilled. He had covid-19 vaccine reaction like nausea, fatigue, loss of appetite and lethargic after covid vaccines. He was not hospitalized due to reactions with Covid 19 Vaccine. He mentioned that he had 30 concomitant medication which he could not recall.  No treatment medications were reported.  The reporter assessed the events of lethargic, appetite lost, fatigue and nausea as possible to Moderna vaccine.  The reporter did not provide any causality assessment for the events of sickness and pain with Moderna vaccine.  The reporter assessed events of sickness, pain, lethargic and nausea as not related to Rinvoq.  The reporter did not provide any causality assessment for the event of appetite lost and fatigue with Rinvoq.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in