pain in the right hand/he patient mentioned a lot of pain; like a nodule with fluid on the wrist/A nodule, pocket of fluid formed on my wrist; the nodule is not there any more but that some mornings the fingers are still stiff; My right hand was in pain, stiff, and swelling; My wrist continued to swell and remain tender to the touch; Tired; Sit of injection was red, swollen all week; Sit of injection was red, swollen all week; It was difficult to move, stretch hand and fingers; This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (pain in the right hand/he patient mentioned a lot of pain), SKIN MASS (like a nodule with fluid on the wrist/A nodule, pocket of fluid formed on my wrist), MUSCULOSKELETAL STIFFNESS (the nodule is not there any more but that some mornings the fingers are still stiff), MOBILITY DECREASED (It was difficult to move, stretch hand and fingers) and PERIPHERAL SWELLING (My right hand was in pain, stiff, and swelling) in a 56-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 050C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hypothyroidism (Levels vary, Normal with flare ups.) since 22-Jul-2011, Lymphoedema (Swelling increases, Aches.) since 05-Feb-2019, Food allergy (Runny Nose) since 13-Jul-2019, Pollen allergy (Runny nose) since 13-Jul-2019, Seasonal allergy (Runny Nose) since 13-Jul-2019 and Gadolinium deposition disease (Runny Nose) since 13-Jul-2019. Concomitant products included PARACETAMOL (TYLENOL) from 22-Jul-2021 to an unknown date and CAMELLIA SINENSIS EXTRACT (GREEN TEA [CAMELLIA SINENSIS EXTRACT]) from 01-Jan-2012 to an unknown date for Lymphedema, MELOXICAM for an unknown indication.    On 13-Jul-2021 at 2:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 14-Jul-2021, the patient experienced MOBILITY DECREASED (It was difficult to move, stretch hand and fingers). On 14-Jul-2021 at 6:00 AM, the patient experienced PAIN IN EXTREMITY (pain in the right hand/he patient mentioned a lot of pain), SKIN MASS (like a nodule with fluid on the wrist/A nodule, pocket of fluid formed on my wrist), MUSCULOSKELETAL STIFFNESS (the nodule is not there any more but that some mornings the fingers are still stiff), PERIPHERAL SWELLING (My right hand was in pain, stiff, and swelling), TENDERNESS (My wrist continued to swell and remain tender to the touch), FATIGUE (Tired), VACCINATION SITE ERYTHEMA (Sit of injection was red, swollen all week) and VACCINATION SITE SWELLING (Sit of injection was red, swollen all week). On 31-Jul-2021, PAIN IN EXTREMITY (pain in the right hand/he patient mentioned a lot of pain), SKIN MASS (like a nodule with fluid on the wrist/A nodule, pocket of fluid formed on my wrist), MUSCULOSKELETAL STIFFNESS (the nodule is not there any more but that some mornings the fingers are still stiff), MOBILITY DECREASED (It was difficult to move, stretch hand and fingers), PERIPHERAL SWELLING (My right hand was in pain, stiff, and swelling), TENDERNESS (My wrist continued to swell and remain tender to the touch), FATIGUE (Tired), VACCINATION SITE ERYTHEMA (Sit of injection was red, swollen all week) and VACCINATION SITE SWELLING (Sit of injection was red, swollen all week) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       Treatment  information: Patient took motrin and soaked  wrist in epson salt. Used ice packs, hot packs, massage therapy, nothing helped the pain. As a Concomitant,  patient took Tumeric and Ginger since 01/01/2012.   Patients race is Black.  As a Concomitant,  patient took MSM and  Collagen powder since 22/07/2021.   Most recent FOLLOW-UP information incorporated above includes: On 05-Aug-2021: Follow-up received on 05-08-2021 Patient identifiers, event, Medical history, Concomitant medication were updated and it is a significant