My lips began to rapidly swell. Woke to really severe swelling in my lips; Blistering Rash appeared to appear around my neck, on my face near my mouth, and spread to my fingers, my ankle, my waist, my leg and my abdomen.; It appeared to be like poison ivy, which she is allergic to. She had not been outside, nor exposed to poison ivy; Blistering near to the mouth.They were so swollen, they actually cracked and bled a little; I noticed my throat felt weird like it was swelling; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of LIP SWELLING (My lips began to rapidly swell. Woke to really severe swelling in my lips), RASH VESICULAR (Blistering Rash appeared to appear around my neck, on my face near my mouth, and spread to my fingers, my ankle, my waist, my leg and my abdomen.), HYPERSENSITIVITY (It appeared to be like poison ivy, which she is allergic to. She had not been outside, nor exposed to poison ivy), LIP BLISTER (Blistering near to the mouth.They were so swollen, they actually cracked and bled a little) and PHARYNGEAL OEDEMA (I noticed my throat felt weird like it was swelling) in a 68-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 001A21A and 001A21A) for COVID-19 vaccination.     Concurrent medical conditions included Poison ivy rash (Since childhood.Starting rash is a blister which spreads to a more systemic blistering rash over pops up where patient  had severe outbreaks in previous years.), Vegetable allergy (mild reactive to winter squash) and Egg allergy (mild reactive to egg white). Concomitant products included VITAMIN D [VITAMIN D NOS] for an unknown indication.   On 03-Mar-2021 at 10:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 31-Mar-2021 at 10:00 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Mar-2021, the patient experienced LIP SWELLING (My lips began to rapidly swell. Woke to really severe swelling in my lips), RASH VESICULAR (Blistering Rash appeared to appear around my neck, on my face near my mouth, and spread to my fingers, my ankle, my waist, my leg and my abdomen.), HYPERSENSITIVITY (It appeared to be like poison ivy, which she is allergic to. She had not been outside, nor exposed to poison ivy), LIP BLISTER (Blistering near to the mouth.They were so swollen, they actually cracked and bled a little) and PHARYNGEAL OEDEMA (I noticed my throat felt weird like it was swelling). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) (oral) from 19-Mar-2021 to 23-Mar-2021 for Rash vesicular, at a dose of 2 tablets/4 hours. On 25-Mar-2021, LIP SWELLING (My lips began to rapidly swell. Woke to really severe swelling in my lips), RASH VESICULAR (Blistering Rash appeared to appear around my neck, on my face near my mouth, and spread to my fingers, my ankle, my waist, my leg and my abdomen.), HYPERSENSITIVITY (It appeared to be like poison ivy, which she is allergic to. She had not been outside, nor exposed to poison ivy) and LIP BLISTER (Blistering near to the mouth.They were so swollen, they actually cracked and bled a little) had resolved. At the time of the report, PHARYNGEAL OEDEMA (I noticed my throat felt weird like it was swelling) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: unknown (Inconclusive) did get a blood test to measure allergic reactions to foods.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       Patient reported she noticed about an hour after the vaccine the swelling a blistering rash. Sha said the rash was breaking out in places where , in the past years she had had blisters severely, when she got exposure to poison ivy. It seemed to become systemic and that happened. However, that process takes days, not minutes as in the  case. Patient referred that after she slept  they were so swollen that they cracked and blend a little and seeping a yellow fluid where they were splitting. That continued for a few  days with the swelling coming down until they were normal- about 5 or 6 days, all told. The rash took longer to ease, possibly a week.   Patient called her doctor on unknown date. The physician said the events could not possibly be a vaccine reaction this far out, and that was probably allergic to chicken, which was the meal the patient had.