an unwell feeling; Decreased appetite; Diarrhea; Bump on the arm at the site; Sugar dropped; Tiredness; Headache; Muscle pain; Chills; Joint pain; Nausea; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) (patient).  A 77 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 29Sep2021 17:00 (Lot number: 301358A) at the age of 77 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Diabetes mellitus" (ongoing), notes: Verbatim: Diabetic; "Heart conditions" (ongoing), notes: Verbatim: Heart conditions; "Asthma" (ongoing), notes: Verbatim: Asthma. Concomitant medication(s) included: METFORMIN taken for diabetes mellitus; GLIMEPIRIDE taken for diabetes mellitus. Vaccination history included: Bnt162b2 (1st dose:, Lot Number:EN6203), administration date: 26Feb2021, when the patient was 76 years old, for COVID-19 immunization; Bnt162b2 (2nd dose:, Lot Number:EP7534), administration date: 19Mar2021, when the patient was 76 years old, for COVID-19 immunization. The following information was reported: FATIGUE (non-serious) with onset 01Oct2021, outcome "recovering", described as "Tiredness"; HEADACHE (non-serious) with onset 01Oct2021, outcome "not recovered", described as "Headache"; MYALGIA (non-serious) with onset 01Oct2021, outcome "recovering", described as "Muscle pain"; CHILLS (non-serious) with onset 01Oct2021, outcome "recovered" (Oct2021), described as "Chills"; ARTHRALGIA (non-serious) with onset 01Oct2021, outcome "recovered" (04Oct2021), described as "Joint pain"; NAUSEA (non-serious) with onset 01Oct2021, outcome "recovered" (04Oct2021), described as "Nausea"; MALAISE (non-serious), outcome "unknown", described as "an unwell feeling"; DECREASED APPETITE (non-serious) with onset 01Oct2021, outcome "recovered" (04Oct2021), described as "Decreased appetite"; DIARRHOEA (non-serious) with onset 01Oct2021, outcome "recovered" (04Oct2021), described as "Diarrhea"; LIMB DISCOMFORT (non-serious) with onset 01Oct2021, outcome "not recovered", described as "Bump on the arm at the site"; BLOOD GLUCOSE DECREASED (non-serious) with onset 01Oct2021, outcome "recovering", described as "Sugar dropped". Relevant laboratory tests and procedures are available in the appropriate section.  Additional Context: Caller on the line calling about the Pfizer Booster, clarified to be Pfizer Covid-19 Booster. She had no reaction to the first two vaccines, but with the  third one had a terrible reaction. Event Details:  Caller clarified terrible reaction to be tiredness, headache, muscle pain, chills, joint pain, nausea, an unwell feeling , decreased appetite, diarrhea, bump on the arm at the site. She mentioned she will go to Dermatologist later today regarding this. Tiredness: The first 4-5 days it was the worst Caller later added, she is a diabetic and her sugar dropped.  Chills: Caller stated it went away around 04Oct2021 and confirmed she has recovered completely from it. Caller stated this still continues to be an issue, but it's better now. She initially stated it could be the diabetic medicine as her provider has changed the medicine.  She stated she was taking Metformin 4 500mg tablets a day and it was changed to 2 500mg tablets a day.  She also mentioned she was on Glimepiride, 2mg, but she is no longer on it and the provider took this out. She confirmed she does not have the Metformin and Glimepiride to provide lot/exp/NDC. Later in call when attempting to clarify when this change occurred, she stated it was a few days before she got the booster.  PSCC Communication: Details captured as provided. Attempts made to clarify information provided. Details captured as provided and clarified.  Concomitant Medications: Is on a list of medications, but no additional details provided. Adverse Event (AE) Details: Provide the time of onset of AE(s): These all started at 2 in the afternoon. She was done down for the count. She was out with her daughter and when came back she laid down and daughter told her she was delirious. Prior Vaccinations (within 4 weeks) : None   No follow-up attempts are possible. No further information is expected.