This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient. A 74 year-old female patient received bnt162b2 (BNT162B2), administration date 24Mar2021 (Lot number: ER8730) at the age of 74 years as dose 2, single for covid-19 immunisation. The patient had no relevant medical history. The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (First Dose, LOT: EN6198, first dose injected into her arm), administration date: 24Feb2021, when the patient was 74 years old, for COVID-19 Immunization, reaction(s): "Rash", "Granuloma annulare", "She says then she noticed she had two spots, one on her upper right leg thigh and that was red spots also the size of maybe a half dollar", "she had kind of like a rash where every pore at the bottom part of her leg was". The following information was reported: GRANULOMA ANNULARE (non-serious) with onset Apr2021, outcome "not recovered", described as "Granuloma annulare"; RASH (non-serious) with onset Mar2021, outcome "not recovered", described as "the rash started to spread and went to all of her leg upper, with some on her back that spread really bad."; RASH MACULAR (non-serious), RASH MACULAR (non-serious) all with onset Mar2021, outcome "not recovered" and all described as "She says she had red spots on her back and then red blotchy stuff"; DRY SKIN (non-serious) with onset Mar2021, outcome "not recovered", described as "She says she is still taking it simply because everything gets so dry". The events "granuloma annulare", "the rash started to spread and went to all of her leg upper, with some on her back that spread really bad.", "she says she had red spots on her back and then red blotchy stuff", "she says she is still taking it simply because everything gets so dry" and "she says she had red spots on her back and then red blotchy stuff" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of granuloma annulare, rash, rash macular, dry skin, rash macular. Additional information: Reporter says she got her first COVID-19 shot 24Feb2021 then approximately a week and a half later, though she thinks sooner then when she noticed it, she had kind of like a rash where every pore at the bottom part of her leg was red. She says then she noticed she had two spots, one on her upper right leg thigh and that was red spots also the size of maybe a half dollar and she also had one spot on her stomach that was about the same size. She says her second Pfizer COVID-19 vaccine dose was 24Mar2021, and then the rash started to spread and went to all of her leg upper, with some on her back that spread really bad. She says she had red spots on her back and then red blotchy stuff. She says it was at that time she went to the dermatologist who gave her some ointment to take. She said she got her booster shot on 29Nov2021 with LOT FD0809. Reporter said she was given the ointment in July first by her primary care doctor who gave her a couple of small tubes to put on the two little spots, and this didn't really do anything. She says her dermatologist gave her the same thing as a bigger container, which by that time she had the rash all over her body. Reporter said the ointment she was given for treatment with Triamcindlon. She said she was still taking it simply because everything gets so dry, that this keeps it so it is moist. She says she doesn't put it on as she was supposed to as two times a day, though she did in the beginning. She says after November they just decided she really didn't need to put it on twice a day, just once or whenever it was needed to keep it moist. She says it didn't show any sign of doing anything. Reporter said for other treatment she is taking a pill, which then the rash started to kind of go away, but then she got the booster shot and the rash spread again. She says the pills she is taking is Hydroxychloroquine, and that has seemed to help. She says she takes Hydroxychloroquine 200mg tablets, she takes one twice a day by mouth, and 14Jul2021 was when she took that the first day, when she had also seen the dermatologist. Hydroxychloroquine /LOT/EXP: Unknown, Reporter says this was dispensed in an orange pharmacy bottle. Reporter clarifies the rash started in March 2021, but it didn't really do anything really at the time, she hadn't seen anybody and didn't think anything of where it came from. She says what they have diagnosed her with is somewhat related to a medicine change, but she hasn't changed anything. She says that her primary care doctor took some biopsies, and also her doctor  sent her what explained it could be Granuloma annulare. She says she sees her doctor in April, so that was given to her in April, and they took one biopsy of her arm, which at that time it was on her arm too. She clarifies that it was sometime in April that she got this paper that says what they think it was. She says the only other thing was when she got the booster shot after the rash had started to go away, with her spots fading and stuff a little bit. She says she got the booster dose and it spread again to areas it hadn't been prior. She says it was on her arms before this and also kind a on her back, but was more or less back and back of her arms. She says thank it didn't itch. She says she believe that the dermatologist, took pictures and told her when she was there last month that she has everything documented. Follow-up attempts are completed. No further information is expected.