The arm tenderness started that evening after first shot and lasted for 48 hours. With the 2nd dose, it was the same; Left arm mildly sore and tender after injection; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 80 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in arm left, administration date 10Feb2021 (Lot number: EL9265) at the age of 79 years as dose 2, single and intramuscular, administered in arm left, administration date 20Jan2021 (Lot number: EL3246) as dose 1, single for covid-19 immunisation. Relevant medical history included: "Thyroid" (unspecified if ongoing), notes: Thyroid; "Glaucoma" (unspecified if ongoing); "Hypothyroidism" (unspecified if ongoing); "Diarrhea" (unspecified if ongoing), notes: If they ever get CT scan, she cannot drink it, she had to have the IV one. She gets severe diarrhea; "contrast dye allergy" (unspecified if ongoing); "Red dye in medication gives her rashes" (unspecified if ongoing), notes: Red dye allergy; "Compromised immune status" (unspecified if ongoing); "respiratory illness" (unspecified if ongoing); "genetic/chromosomal abnormalities" (unspecified if ongoing); "endocrine abnormalities (including diabetes)" (unspecified if ongoing); "Diabetes" (unspecified if ongoing); "Obesity" (unspecified if ongoing).   Concomitant medication(s) included: SYNTHROID taken for hypothyroidism; BIMATOPROST taken for glaucoma. Past drug history included: Ampicillin, reaction(s): "Rashes", notes: Rashes; Macrobid, reaction(s): "Rash". Vaccination history included: Flu shot (Flu shot), administration date: 2018, reaction(s): "Tingling". The following information was reported: TENDERNESS (non-serious) with onset 20Jan2021, outcome "recovering", described as "The arm tenderness started that evening after first shot and lasted for 48 hours. With the 2nd dose, it was the same"; PAIN IN EXTREMITY (non-serious) with onset 20Jan2021, outcome "recovering", described as "Left arm mildly sore and tender after injection".  Additional information: for concomitant products Synthroid, took since 58 years, for over 25 years and Lumigen (Bimatoprost), took for close to 10 years. First and second shots were also the Pfizer COVID vaccine. First one was given on 20Jan2021, Lot EL3246, expiration unknown. The second one was given 10Feb2021 with Lot EL9265, expiration unknown. The arm tenderness started that evening after first shot and lasted for 48 hours. With the 2nd dose, it was the same. It was just a little tender after injection for 48 hours with no redness. She did not feel anything during the injection but assumed it was given in the muscle. The left arm was sore after the injection. She was very healthy and takes Synthroid, Lumigen drops and she took other vitamins and supplements that she had been on for 10 years. They are normal vitamins. No further details provided on the vitamins and supplements. 1st dose with left arm mildly sore and tender after injection in the afternoon. Shot was at noon and about 4 hours later, her arm was tender. Emergency Room and Physician Office reported with held. She found it very interesting. She did not had a temperature and it was weird. She had not ever had the flu and she does not take a flu shot. But she got the flu shot in 2018, and this same thing happened. She does not have a manufacturer, lot or expiration for it. No family medical history. No test done and her doctor did not do a urinalysis or anything, just a thorough exam.  Follow-up attempts completed. No further information expected.