This spontaneous report was received from a consumer regarding his wife, a female patient of unknown age. She was reported to have unknown blood type as to every time, has characteristics of several different types. Her medical history, drug reactions/allergies, and concomitant medications were not reported. On an unknown date, the patient started therapy with [therapy unspecified] (reported as childhood vaccination) for prophylaxis (dose, route, lot#, and expiration unknown). The patient had childhood vaccination three times and patient's body was able to get rid of it where there are no traces of any vaccination (vaccination failure). The outcome of the event vaccination failure was unknown. Causality of the event was not provided. This is a non-valid report due to lack of identifiable suspect therapy. Follow up information was received from the patient on 30-MAR-2018 regarding herself. On an unknown date, the patient had a wrist surgery and was diagnosed with kidney damage (renal injury) and epilepsy, it was reported that she did not have any symptomology of either aforementioned medical issue. Additionally, it was stated that the patient had a direct exposure to the flu, strep throat and hepatitis C, however, she had not developed any of the symptomology and as long as she could remember, she had the ability to resist sickness in both bacteria and virus form and that she was also a very quick healer. The reporter and her husband believed that there were atypical characteristics in the patient's blood that assist her immune system with that ability. The outcome of the events wrist surgery, renal injury and epilepsy and the causal relationship between the events and therapy with [therapy unspecified] were not reported. Follow up information has been received from the 45 years old female patient referring herself on 11-FEB-2019. It was reported that the patient was not pregnant and she had anaphylactic reaction to penicillin. The patient had been vaccinated as a child with all of her childhood immunizations and despite her vaccinations she has repeatedly had to receive revaccinations due to lack of titers. The patient had M-M-R II (strength, dose, route, lot# and expiration date were unknown) several times with no titers for it (vaccination failure) and had been administered M-M-R II at least 3 or 4 times including a vaccination in 1993 and another "more recently" after applying for a job as a teacher, and the patient had to repeat the vaccine series for an unspecified hepatitis vaccine (manufacturers unknown) on unknown dates. The patient also mentioned that when she tried to take a simple over the counter medication, such as (acetaminophen) TYLENOL and (acetaminophen) TYLENOL with codeine, she usually passed it whole. The patient was extremely healthy, in fact she further explained that she experienced extremely fast healing, and in general if she got a typical cold or stomach virus she experienced symptoms for no more than 12 hours before she was completely recovered. The patient stated that at one point she was prescribed antibiotics for an unspecified kidney infection, and that the unspecified antibiotic medication she was prescribed to take made her more sick than the sickness itself. The patient said that in general she did not take medications as her body did not respond to them. Treatment was not given for the events. Lab diagnostics/studies was performed included urine tests. The patient had sought medical attention. The outcome of the events was not recovered. The causality between the events and M-M-R II was not reported. Upon internal review, the event of kidney infection was determined to be medically significant. Upon receipt of follow-up information it was determined that this case now is valid, because the one of unspecified vaccines was identified.