still did not feel good; legs were weak/arms were weak/still with some weakness on her legs; a terrible reaction after getting the 2nd booster dose of the Moderna; whole body was weak/was very weak/still weak but can walk around with walker; She fell 3x that day; could barely stand up; This spontaneous case was reported by a patient and describes the occurrence of MALAISE (still did not feel good), MUSCULAR WEAKNESS (legs were weak/arms were weak/still with some weakness on her legs), IMMUNISATION REACTION (a terrible reaction after getting the 2nd booster dose of the Moderna), ASTHENIA (whole body was weak/was very weak/still weak but can walk around with walker) and FALL (She fell 3x that day) in a 76-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 038K20A, 031M20A and 034F21A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     Previously administered products included for Product used for unknown indication: flu vaccine in 2021. Past adverse reactions to the above products included No adverse event with flu vaccine. Concurrent medical conditions included Allergic reaction to drug, Drug allergy (reactions to a lot of meds), Hypertension (both present prior to getting the vaccine) and Anxiety (both present prior to getting the vaccine). Concomitant products included METOPROLOL and ALPRAZOLAM (XANAX) for an unknown indication.   On 29-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 09-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 21-May-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 22-May-2022, the patient experienced MUSCULAR WEAKNESS (legs were weak/arms were weak/still with some weakness on her legs), IMMUNISATION REACTION (a terrible reaction after getting the 2nd booster dose of the Moderna), ASTHENIA (whole body was weak/was very weak/still weak but can walk around with walker), FALL (She fell 3x that day) and DYSSTASIA (could barely stand up). On 24-May-2022, the patient experienced MALAISE (still did not feel good). The patient was treated with OXYGEN at an unspecified dose and frequency. At the time of the report, MALAISE (still did not feel good) had not resolved and MUSCULAR WEAKNESS (legs were weak/arms were weak/still with some weakness on her legs), IMMUNISATION REACTION (a terrible reaction after getting the 2nd booster dose of the Moderna), ASTHENIA (whole body was weak/was very weak/still weak but can walk around with walker), FALL (She fell 3x that day) and DYSSTASIA (could barely stand up) was resolving.            Patient did not diagnose with or tested positive for Covid-19. Patient calls in to report a terrible reaction after getting the 2nd booster dose of the Moderna Covid-19 vaccine. She states that in the morning after she got the 2nd booster dose (22-May-2022), her whole body, legs and arms were weak and she could barely stand up. She fell thrice that day because she was very weak. On her 3rd fall, she called the paramedics and she was brought to the emergency room (ER) early in the morning of 23-May-2022. She was put on oxygen and was given IV fluids with antibiotics and antihistamines. She stayed in the ER for about 5 hours and was sent home. She was still weak, can walk around but with a walker. The paramedics and the doctors who attended to her in the ER thought that her condition was from the booster.On 24-May-2022, she went to an urgent care because she still did not feel good. On 06-Jun-2022, she consulted her primary care physician and was told that she worked through her reaction to the vaccine. The AE cause patient to seek medical care (ER) the patient did not experience a similar event in the past. The patient symptoms improved.  Lot number for the second booster dose was 042(?)21A