They are having twitching and pulsating mainly in the legs and sometimes other parts of the body; Taken a toll emotionally and physically on them,  this has effected their lives; This is a spontaneous report from a non-contactable consumer. This consumer (patient's father) reported for a female patient (reporter's daughter) that a female patient of an unknown age received second dose of bnt162b2 (Pfizer-Biontech COVID-19 Vaccine, solution for injection, batch/lot number: unspecified), via an unspecified route of administration on an unspecified date as single dose for COVID-19 immunisation. The patient received first dose of bnt162b2 (Pfizer-Biontech COVID-19 Vaccine, solution for injection, batch/lot number: unspecified) on an unspecified date as historical vaccination as single dose for covid-19 immunisation and no reaction on previous exposure to drug. The patient's medical history and concomitant medications were not reported. Report on behalf of his family. His wife, and 2 daughters and one son. His son and himself had both received "both Pfizer vaccine doses and have had no side effects at all. His wife and one daughter had both Pfizer vaccines, and one daughter has had only one dose of the vaccine. " His wife, son, one daughter and himself did not experience any side effects after their first dose. His youngest daughter was having the exact same symptoms the other 2 women were having after she has received only one dose. They had read all information and have been seen by their PCP for these symptoms and the HCP said, it will go away, don't worry." There has been "no progress in the past 3 weeks, as far as decreasing symptoms and it has taken a toll emotionally and physically on them, this has affected their lives. They have all had the Pfizer vaccination administered last month, they are past the 2 doses and past the 2 weeks. They were 3 weeks out from their second vaccinations. What they have had as far as symptoms, was a symptom that his wife and 2 daughters experienced. His son, himself, his wife and 2 daughters received all received the Pfizer vaccine. His son and him had no symptoms or any issues following the second dose. His wife and 2 daughters were still having issues with pulsating or twitching, mainly in the legs and sometimes all parts of their body. It was frequent and infrequent depending on the time of day. They waited to see if it would subside or improve, but it was persisting, and they were concerned. He was not sure if it was a genetic type issue. His son and him were males and have no issues, but his wife and 2 daughters were the ones that have similar symptoms. His youngest daughter, who recently became eligible, has only received 1 dose and the others already completed second dose. After first dose, his daughter had similar symptoms, where the others, the first go around had no issues. He was kind of worried, was this something that has also been heard of or anything that speaks to either the nervous system or the pulsating and twitching? The outcome of the event "They are having twitching and pulsating mainly in the legs and sometimes other parts of the body" was not recovered, while the outcome of event taken a toll emotionally and physically on them, this has affected their lives was unknown.  Reporter declined to provide any demographic information.  Follow-up (21Jun2021): This is a follow up spontaneous report from a contactable consumer. This consumer (patient's father) reported for a female patient (reporter's daughter) that:  No follow-up attempts are possible; information about lot/batch number cannot be obtained.; Sender's Comments: Linked Report(s) : US-PFIZER INC-2021748991 same reporter/drug/event, different patients.