tanking of blood pressure; really bad spell of feeling like she was walking into walls; microclots in her vascular system; it affected my dysautonomia by causing me to go back 30 years in my dysautonomia or 25 years; it affected my dysautonomia by causing me to go back 30 years in my dysautonomia or 25 years/ tanking of blood pressure; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 62-year-old female patient received BNT162b2 (BNT162B2), on 02Apr2021 as dose 1, single (Lot number: ER8732, Expiration Date: Jul2021) at the age of 62 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Dysautonomia", start date: 1996 (ongoing), notes: medical condition that she has had for over 25 years; "raise her blood pressure" (unspecified if ongoing), notes: taking Midodrine and Florinef to raise her blood pressure prior to the vaccine; "microclots" (unspecified if ongoing). The patient did not have prior vaccinations within 4 weeks. Concomitant medication(s) included: PENTOXIFYLLINE oral taken for autonomic nervous system imbalance, start date: 1996 (ongoing); GABAPENTIN oral taken for autonomic nervous system imbalance, start date: 1996 (ongoing); DONNATAL oral taken for autonomic nervous system imbalance, start date: 1996 (ongoing); CLONAZEPAM oral taken for autonomic nervous system imbalance, start date: 1996 (ongoing); CITALOPRAM oral taken for autonomic nervous system imbalance, start date: 1996 (ongoing). The patient reported "tanking of blood pressure" as she received Pfizer COVID-19 vaccine and wanted to know if low blood pressure was previously reported after getting the vaccine. She also mentioned, "I have dysautonomia it affected my dysautonomia by causing me to go back 30 years in my dysautonomia or 25 years." The patient further reported that she has had a two-year reaction, she has been sick for almost two years, about 23 months. She got the Pfizer COVID vaccine on 02Apr2021 and knew something was not right 2 weeks and three days after that vaccine; she only got one dose. She went to the ER one night in Jul2021 and confirmed she was admitted to the hospital for one night because she had a "really bad spell of feeling like walking into walls." She has a medical condition that she has had for over 25 years called dysautonomia; she was stabilized and took medications and looked into this and read that it was ok to take the vaccine and her doctor said it was also ok. She explains being sick as her blood pressure started tanking after the vaccine. She was taking Midodrine and Florinef to raise her blood pressure prior to the vaccine. The doctor tripled her midodrine medication and doubled the Florinef medication. She was still taking medication and started eating more salt, she found out since that there were issues going on in her body and this was the reason she was not feeling better. She took other medications for dysautonomia and has been taking these since 1996. She just wanted to know how she can get better and her doctor did not know what to do. There were a lot of people that have been injured from the vaccine and she assumed that Pfizer knew this. At the time of report, she has been taking 3 new medications for a week. The first one was Eliquis 5mg tablet twice a day by mouth, she was s taking this because a doctor discovered that she had microclots in her vascular system. Second one was Aspirin 81mg once a day. Third one was Famotidine 40mg twice a day. The events "tanking of blood pressure" and "really bad spell of feeling like she was walking into walls" required physician office visit and emergency room visit. She went to her regular doctor after the vaccine but just recently started to going to see other doctors that have realized what the vaccine has caused. Outcome of the event "really bad spell of feeling like she was walking into walls" was recovered, while the remaining events was unknown.