Vomiting; violent retching; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP).  A 74-year-old female patient received BNT162b2 (BNT162B2), on 10Jun2022 as dose 4 (booster), single (Lot number: FP4554) at the age of 74 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "COVID" (unspecified if ongoing), notes: she had COVID in the very beginning, but then she got all her vaccines; "she has a pacemaker" (unspecified if ongoing); "plaque" (unspecified if ongoing); "Heart medication" (unspecified if ongoing). Concomitant medication(s) included: ELIQUIS taken for cardiac disorder; LOSARTAN taken for cardiac disorder; SYNTHROID taken for cardiac disorder; ATORVASTATIN taken for aortic arteriosclerosis. Past drug history included: Flu vaccine for Immunization, notes: She does not get ill from the flu vaccine. Vaccination history included: BNT162b2 (dose 3, Single, injection to right arm, Lot: FF2589), administration date: 11Oct2021, when the patient was 73-year-old, for COVID-19 immunization; BNT162b2 (Dose 2, Single, injection to right arm, Lot: EN6201), administration date: 28Feb2021, when the patient was 72-year-old, for COVID-19 immunization, reaction(s): "Achy", "Chills", "Fever"; BNT162b2 (Dose 1, single in injection to right arm Lot: EL9265), administration date: 07Feb2021, when the patient was 72-year-old, for COVID-19 immunization, reaction(s): "Achy", "Chills", "Fever". The following information was reported: VOMITING (non-serious) with onset Jun2022, outcome "unknown"; RETCHING (non-serious) with onset Jun2022, outcome "unknown", described as "violent retching". Therapeutic measures were not taken as a result of vomiting, retching.  Additional information:  With the last 2 doses of the Pfizer Covid-19 Vaccine she had vomiting. She clarified she just had the last Pfizer Covid-19 Vaccine, Bivalent booster on 01Nov2022. The second to last dose she violently threw up for almost 24 hours with. 04Nov2022 she is so weak, she understands part of it, but does not know anyone else who throws up. She does not know if this is an allergic reaction to the product. She does not know if she can do this again. Since Tuesday, today she is finally back in the real world, she was close to going to the hospital she was so sick. If she didn't have it twice, she would think maybe she had a bug, but it has happened with the last 2 vaccines. They used to tell her in the beginning, the first couple she had the chills and the fever, but she did not have a fever 03Nov2022 and did not have chills. But the extreme vomiting she had. Just talking about this is making her sick. She needs Zofran or something because of how deathly ill she is. She does not get ill from the flu vaccine. With the last 2 doses she had onset of violent retching, vomiting about 8-10 hours after administration that lasted for almost 24 hours. With the first 2 doses she was achy, had chills, fever for about 24 hours. She verified there are no relevant other medical conditions to report. She walks, drives, does her own house, lives alone, watches grandbabies. She is as active as she can be. She verified that there have been no relevant treatments or medical interventions to report.;