headaches; flu like symptoms; injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm; injection site became red and warm and it hurt for a couple of days, then the redness grew to; injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm; This spontaneous case was reported by a nurse (subsequently medically confirmed) and describes the occurrence of HEADACHE (headaches), INFLUENZA LIKE ILLNESS (flu like symptoms), VACCINATION SITE ERYTHEMA (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm), VACCINATION SITE WARMTH (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm) and VACCINATION SITE PAIN (injection site became red and warm and it hurt for a couple of days, then the redness grew to) in a 55-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 012A21A) for COVID-19 vaccination.     The patient's past medical history included Psychosis (now under control). Concurrent medical conditions included Major depression, Panic disorder, Thyroid disorder NOS and Obesity.    On 17-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Mar-2021, the patient experienced VACCINATION SITE ERYTHEMA (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm) and VACCINATION SITE PAIN (injection site became red and warm and it hurt for a couple of days, then the redness grew to). On an unknown date, the patient experienced HEADACHE (headaches) and INFLUENZA LIKE ILLNESS (flu like symptoms). an unknown date, the patient experienced VACCINATION SITE WARMTH (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency. At the time of the report, HEADACHE (headaches) and INFLUENZA LIKE ILLNESS (flu like symptoms) had not resolved and VACCINATION SITE ERYTHEMA (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm), VACCINATION SITE WARMTH (injection site became red and warm and it hurt for a couple of days, then the redness grew to halfway down the arm) and VACCINATION SITE PAIN (injection site became red and warm and it hurt for a couple of days, then the redness grew to) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   The patient consulted with a health care professional who recommended diphenhydramine and icing of the area. The patient took diphenhydramine, applied ice on the area and ibuprofen (may be).  Concomitant medications included medications for several conditions, like major depression, panic disorder, psychosis (now under control) and  thyroid medication.