States her cholesterol is always 75 and is now 200; facial droop or pain in her face; noticed her arms started getting numb and swelling up; noticed her arms started getting numb and swelling up; facial droop or pain in her face; talk with the slur; tingling in her fingers; ended up in the emergency room and had a stroke; she had blood clots on the brain from the stroke; she went into the ER her blood pressure was 200/180; This is a spontaneous report from a contactable consumer (patient) and a contactable physician. A 51-year-old female patient received bnt162b2 (Lot Number: ER8730; Expiration Date: 31Jul2021), second dose via an unspecified route of administration, administered in left arm on 11Apr2021 (early in the morning) at the age of 51-year-old as 2nd dose, single for covid-19 immunization. Medical history included ventricular septal defect from an unknown date and unknown if ongoing (she was born with a hole in her heart but that had closed up and when she had the stroke, the hole opened back up and they told her she had blood clots on the brain from the stroke). There were no concomitant medications. The patient previous received first dose of bnt162b2 (Batch/Lot Number: ER2613; Expiration Date: 31Jul2021), via an unspecified route of administration, administered in left arm on 21Mar2021 single dose for covid-19 immunization. The patient experienced stroke on 20Apr2021, she had blood clots on the brain from the stroke on 20Apr2021, blood pressure was 200/180 on 20Apr2021, her cholesterol is always 75 and is now 200 on an unspecified date, facial droop on an unspecified date, her arms started getting numb and swelling up on an unspecified date, pain in her face on an unspecified date, talk with the slur/ slurred speech on an unspecified date. The events her arms started getting numb and swelling up, pain in her face and talk with the slur/ slurred speech were serious per hospitalization; stroke, she had blood clots on the brain from the stroke, blood pressure was 200/180, her cholesterol is always 75 and is now 200 and facial droop were serious per hospitalization, medically significant. The patient was hospitalized for from 20Apr2021 to an unknown date. The events require a visit to emergency room and physician office. Caller states she is calling about the Pfizer shot and had the 2nd dose on 11Apr2021 and noticed her arms started getting numb and swelling up and she did not do anything about it but 2 days after that she called the facility where she had the Pfizer shot and they said to call her HCP and the HCP was out of town so she spoke with a nurse and was told to go to urgent care at that time. States she went to urgent care and they said her arm was swollen and to rub alcohol on it and she did that and a couple of days after that ended up in the emergency room and had a stroke. States the numbness and swelling was just the whole left side of her body and she went to the emergency room at the hospital on 20Apr2021 but on 16Apr2021 she went to the urgent care; states the numbness and swelling is better but comes and goes with the tingling in her fingers and the numbness, but her face is doing much better and she does not have the facial droop or pain in her face anymore; states her speech is back and she does not talk with the slur anymore. States the facial droop, face pain and slurred speech began when she went to the ER and that was on 20Apr2021 and is now completely resolved. Caller states the 1st dose of her Pfizer Vaccine was administered on 21Mar2021 with lot ER2613, the 2nd dose was administered on 11Apr2021 with lot ER8730; states both doses of the Pfizer Vaccine were administered in her left arm and her patient card does not have the NDC written on it but the expiry date for both doses of the vaccine is 31Jul2021. States the whole year of 2020 she was doing fine till she took the Pfizer Vaccine and that shot everything up regarding her cholesterol levels and Blood pressure which are all high; states her cholesterol is always 75 and is now 200; states she has high blood pressure and when she went into the ER her blood pressure was 200/180; states she was born with a hole in her heart but that had closed up and when she had the stroke, the hole opened back up and they told her she had blood clots on the brain from the stroke. The patient underwent lab tests and procedures which included cholesterol: 200 on 10May2021 (her cholesterol is always 75 and is now 200), blood pressure: 200/180 on 20Apr2021. The outcome of events for stroke, she had blood clots on the brain from the stroke, her blood pressure was 200/180, her cholesterol is always 75 and is now 200, tingling in her fingers were unknown, for other events was resolved on an unspecified date. Vaccination Facility Type: school. No Additional Vaccines Administered on Same Date of the Pfizer Suspect. No Prior Vaccinations (within 4 weeks).