DROP IN HEARING WITH INCREASED TINNITUS; REVACCINATION WITH DIFFERENT COVID-19 VACCINE; This spontaneous report received from a patient concerned a 55 year old female of an unspecified race and ethnic origin. The patient's height, and weight were not reported. The patient's past medical history included: thyroidectomy, and concurrent conditions included: was diagnosed with bilateral autoimmune ear disease on DEC-2020, meniere's disease diagnosed in late 90's remission for 15 years, reoccurred in 2012 and ongoing, hashimotos, and hypoparathyroidism, and other pre-existing medical conditions included: The patient was not pregnant at the time of this report. The patient had no illness at the time of vaccination, no pre-existing acute illness 30 days prior to vaccination, no history of hospitalization in last 30,days, was not breastfeeding at the time of this report. The patient was previously vaccinated with two doses of tozinameran (Pfizer vaccine) (Dose number in series 1) (injection, route of admin not reported, batch number: EN6206 and ER8733, expiry not reported) dose was not reported, administrated at right arm on 10-MAR-2021 (first shot) and 31-MAR-2021 (second shot) for covid-19 prophylaxis.  On an unspecified date the patient experienced drop in hearing with increased tinnitus (Dose number in series 1).  The patient additionally received covid-19 vaccine ad26.cov2.s (Dose number in series 2) (suspension for injection, route of admin not reported, batch number: 1855190 expiry: UNKNOWN) dose was not reported, 01 total administered at upper right arm on 25-APR-2022 for covid-19 prophylaxis which was revaccination with different COVID-19 vaccine (Dose number in series 2). Age at time of vaccination 55 years old. Concomitant medications included golimumab (Simponi) for autoimmune inner ear disease from 2018 approximately changed the route of delivery from auto-injector to injected into ear, methotrexate for autoimmune inner ear disease from SEP-2021 to OCT-2022, levothyroxine sodium (Synthroid) for hashimoto's disease from 1998, calcitriol for hypoparathyroidism from 2001, hydrochlorothiazide/triamterene (Dyazide) for meniere's disease from more than 5 years till OCT-2022, calcium supplement for more than 10 years, colecalciferol (Vitamin D3) supplement for more than 10 years, folic acid from SEP-2021 to OCT-2022 and xantofyl (Lutein) supplement for more than 10 years.  No immediate symptoms after receiving Janssen Vaccine. Approximately 10 days later, on 10-MAY-2022, the patient experienced a drop in hearing with increased tinnitus. An appointment was made with doctor to address symptoms. Decision made to initiate Prednisone 60mg a day for 10 days. The patient was unable to taper prednisone down without drops in hearing. On 28-JUN-2022 prednisone was tapered. Hearing remained diminished with ongoing worsening of tinnitus compared to baseline. Treatment medications (dates unspecified) included: prednisone injections in the ear after oral discontinued. Hearing test was conducted on monthly basis. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from drop in hearing with increased tinnitus, and the outcome of revaccination with different covid-19 vaccine was not reported. This report was non-serious. This case, involving the same patient is linked to 20221148334.