Skin is hypersensitive to touch, like dermatographia; Lump in the throat feeling; Heartburn; Sweating; that heat makes the rash and hives worse.; rash; Red splotches all over the face, back, chest and neck; Hives on the arms / Rash and hives are migrating to different parts of the body. He saw some on his groin and legs but they are more concentrated in the upper half of the body.; red palms; Itchy, red palms; This spontaneous case was reported by a consumer and describes the occurrence of PRURITUS (Itchy, red palms), ERYTHEMA (Red splotches all over the face, back, chest and neck), SENSITIVE SKIN (Skin is hypersensitive to touch, like dermatographia), SENSATION OF FOREIGN BODY (Lump in the throat feeling) and DYSPEPSIA (Heartburn) in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 067F, 038B21A and 045A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Previously administered products included for Product used for unknown indication: Allegra and Zyrtec. Past adverse reactions to the above products included Drowsiness with Zyrtec; and Feeling strange with Allegra. Concurrent medical conditions included Pollen allergy, Allergy to molds, Seasonal allergy and Asthma.   On 18-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 15-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 22-Dec-2021, the patient experienced PRURITUS (Itchy, red palms) and ERYTHEMA (red palms). On 23-Dec-2021, the patient experienced ERYTHEMA (Red splotches all over the face, back, chest and neck) and URTICARIA (Hives on the arms / Rash and hives are migrating to different parts of the body. He saw some on his groin and legs but they are more concentrated in the upper half of the body.). On an unknown date, the patient experienced SENSITIVE SKIN (Skin is hypersensitive to touch, like dermatographia), SENSATION OF FOREIGN BODY (Lump in the throat feeling), DYSPEPSIA (Heartburn), HYPERHIDROSIS (Sweating), RASH (that heat makes the rash and hives worse.) and RASH (rash). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) ongoing since an unknown date for Hives, at an unspecified dose and frequency; LORATADINE (CLARITINE) at an unspecified dose and frequency and FAMOTIDINE (PEPCID [FAMOTIDINE]) ongoing since an unknown date for Heartburn, at an unspecified dose and frequency. At the time of the report, PRURITUS (Itchy, red palms), SENSITIVE SKIN (Skin is hypersensitive to touch, like dermatographia), DYSPEPSIA (Heartburn), HYPERHIDROSIS (Sweating) and ERYTHEMA (red palms) outcome was unknown and ERYTHEMA (Red splotches all over the face, back, chest and neck), SENSATION OF FOREIGN BODY (Lump in the throat feeling), URTICARIA (Hives on the arms / Rash and hives are migrating to different parts of the body. He saw some on his groin and legs but they are more concentrated in the upper half of the body.), RASH (that heat makes the rash and hives worse.) and RASH (rash) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were provided.  Patient tried antihistamines like Claritin, but didn't do anything. When he took Zyrtec, historically, it made him extremely drowsy, and Allegra makes him feel strange on it, so he's been only taking Benadryl. Benadryl seems to help the symptoms quite a lot. He's also tried Pepcid (famotidine) as he's been having heartburn and the feeling of having a lump in the throat. The lump in the throat feeling seems to get worse when he eats. Not sure if it works yet as it was his first time trying it tonight. And that heat makes the rash and hives worse He noticed that when he keeps the house cold and has less clothing on, it makes the rash and hives less bad. so he keeps the house very clean. He also uses hypoallergenic laundry detergent, so he thinks that these symptoms are due to the booster shot.