fuzzy headedness; agitated; mind racing; my impulse control was compromised; mood swings from slight mania to great depression; mood swings from slight mania to great depression; mood swings from slight mania to great depression; My cognition has been impacted as well; short term memory loss; inability to concentrate; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 59 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 15Apr2021 08:45 (Batch/Lot number: unknown) at the age of 59 years as dose 2, single and administered in arm left, administration date 18Mar2021 08:45 (Batch/Lot number: unknown) as dose 1, single for covid-19 immunisation. Relevant medical history included: "traumatic brain injuries", start date: 2005 (unspecified if ongoing); "traumatic brain injuries", start date: 2010 (unspecified if ongoing); "trauma" (unspecified if ongoing), notes: I had severe childhood trauma and suffered two traumatic brain injuries.; "Depression", start date: 2005 (unspecified if ongoing), notes: successfully treated.; "anxiety" (unspecified if ongoing), notes: successfully treated.; "Known allergies: Penicillin" (unspecified if ongoing); "Known allergies: Sulfa Drugs" (unspecified if ongoing); "Known allergies: Pineapple" (unspecified if ongoing); "Known allergies: Mushrooms" (unspecified if ongoing); "Known allergies: Nuts" (unspecified if ongoing); "Depression", start date: 2010 (unspecified if ongoing), notes: successfully treated. Concomitant medication(s) included: PAXIL [PIROXICAM]; GABAPENTIN; ARMOUR THYROID; VITAMIN D3. Past drug history included: Lortab, reaction(s): "Known allergies:Lortab"; Erythromycin, reaction(s): "Known allergies: Erythromycin".  The following information was reported: FEELING ABNORMAL (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "fuzzy headedness"; AGITATION (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "agitated"; TACHYPHRENIA (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "mind racing"; IMPULSE-CONTROL DISORDER (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "my impulse control was compromised"; MOOD SWINGS (non-serious), MANIA (non-serious), DEPRESSION (non-serious) all with onset 16Apr2021 02:00, outcome "unknown" and all described as "mood swings from slight mania to great depression"; COGNITIVE DISORDER (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "My cognition has been impacted as well"; AMNESIA (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "short term memory loss"; DISTURBANCE IN ATTENTION (non-serious) with onset 16Apr2021 02:00, outcome "unknown", described as "inability to concentrate". The events "fuzzy headedness", "agitated", "mind racing", "my impulse control was compromised", "mood swings from slight mania to great depression", "mood swings from slight mania to great depression", "mood swings from slight mania to great depression", "my cognition has been impacted as well", "short term memory loss" and "inability to concentrate" were evaluated at the physician office visit. Therapeutic measures were not taken as a result of feeling abnormal, agitation, tachyphrenia, impulse-control disorder, mood swings, mania, depression, cognitive disorder, amnesia, disturbance in attention.  Additional information: Patient reported that this happened after each of the two vaccinations. Within 24 hours she became agitated, her mind racing, her impulse control was compromised, mood swings from slight mania to great depression. Her cognition had been impacted as well with short term memory loss, an inability to concentrate and fuzzy headedness. Patient told she lost her part time job because of the impact of this over a three weeks period after the first vaccination. When she experienced the exact same response from the second (which she was still having) she knew it was related to the vaccine. Patient had done a great deal of therapy and prior to the vaccinations was functioning at a high level given her disability challenges. Patient told she was glad to be fully vaccinated but was very upset about the reaction. Patient was extremely self-aware and notice any changes in her physical, psychological and emotional status. Patient reported she neither had COVID prior vaccination nor post vaccination. Patient also reported she did not had any vaccination in four weeks of vaccination.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.