fever 100.1; Body aches; headaches; congestion; Tested positive on two different tests.; Tested positive on two different tests.; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 68-year-old male patient received BNT162b2 (BNT162B2), on 27Jan2021 as dose 1, single (Lot number: EL9261), in left arm, on 13Feb2021 as dose 2, single (Lot number: EL9264), in left arm, on 14Oct2021 as dose 3 (booster), single (Lot number: FH8020), in left arm and on 25Apr2022 as dose 4 (booster), single (Lot number: FP4554), in left arm for covid-19 immunisation. The patient's relevant medical history was not reported. There were no concomitant medications. Past drug history included: Penicillin, reaction(s): "Known allergies: Penicillin", notes: Known allergies: Penicillin. The following information was reported: PAIN (non-serious) with onset 13May2022, outcome "recovering", described as "Body aches"; NASAL CONGESTION (non-serious) with onset 13May2022, outcome "recovering", described as "congestion"; PYREXIA (non-serious) with onset 13May2022, outcome "recovering", described as "fever 100.1"; HEADACHE (non-serious) with onset 13May2022, outcome "recovering", described as "headaches"; DRUG INEFFECTIVE (medically significant) with onset May2022, outcome "unknown", COVID-19 (medically significant) with onset May2022, outcome "not recovered" and all described as "Tested positive on two different tests.". The patient underwent the following laboratory tests and procedures: Body temperature: (unspecified date) 100.1; SARS-CoV-2 test: (unspecified date) positive, notes: Tested positive on two different tests; (12May2022) negative, notes: Covid symptoms-tested negative; (18May2022) positive, notes: 18May still positive; (20May2022) negative; (21May2022) positive, notes: 21May-25May - testing positive each day; (22May2022) positive, notes: 21May-25May - testing positive each day; (23May2022) positive, notes: 21May-25May - testing positive each day; (24May2022) positive, notes: 21May-25May - testing positive each day; (25May2022) positive, notes: 21May-25May - testing positive each day; (14May2022) positive, notes: 14May-17May -daily tests were positive; (15May2022) positive, notes: 14May-17May -daily tests were positive; (16May2022) positive, notes: 14May-17May -daily tests were positive; (17May2022) positive, notes: 14May-17May -daily tests were positive. Therapeutic measures were taken as a result of drug ineffective, covid-19, pyrexia, pain, headache, nasal congestion.  Clinical course: Product: COVID 19 Treatment. Brand: PAXLOVID. Treatment start date: 13May2022. Treatment stop date: 18May2022. Lot number: FY9066. Indication: Treatment of COVID-19. Adverse event: 12May2022- Covid symptoms-tested negative. 13May-Body aches, headaches, congestion, fever 100.1. Tested positive on two different tests. Telehealth call with Physician Assistant. 13May - first dose of PAXLOVID at 4:45 PM. 14May-17May -daily tests were positive. Took 2 doses of PAXLOVID each day 12 hours apart. Metallic taste in mouth. 18May still positive and had last dose of PAXLOVID in morning. Isolation ended 19May and feeling okay. 20May - feeling not quite right in evening- test negative. 21May-25May - testing positive each day, very sore throat, metallic taste in mouth, slight cold, sniffles, a lot of sneezing. I have none of the original 12May symptoms. I believe I have Paxlovid rebound. If patient recovered: Recovering (as reported). Other medical history: None - I take no medications.  No follow-up attempts are possible. No further information is expected.