After 2nd dose, 15 hours after receiving the vaccine at 1 am in the morning she felt so bad; she felt so hot; she had some difficulty breathing but not enough to go to the hospital; she had a slight reaction to the second dose with a 102°F temperature/her temperature was 102°F; feeling very sick; This spontaneous case was reported by a patient and describes the occurrence of MALAISE (feeling very sick), FEELING ABNORMAL (After 2nd dose, 15 hours after receiving the vaccine at 1 am in the morning she felt so bad), FEELING HOT (she felt so hot), DYSPNOEA (she had some difficulty breathing but not enough to go to the hospital) and PYREXIA (she had a slight reaction to the second dose with a 102°F temperature/her temperature was 102°F) in a 72-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 026L20A and 004M20A) for COVID-19 vaccination.     Previously administered products included for Drug use for unknown indication: INFLUENZA VACCINE on 15-Oct-2021. Past adverse reactions to the above products included No adverse event with INFLUENZA VACCINE. Concurrent medical conditions included Exercise induced asthma (since she was a child, Recent change in status such as improvement or worsening: no), Hyperparathyroidism (Recent change in status such as improvement or worsening: no) since April 2021, Allergy to antibiotic (Avelox antibiotic), Food allergy (cannot eat chocolate as it gives palpitations specifically she experiences SVT's), Caffeine (as it gives palpitations specifically she experiences SVT's), Drug allergy (MSG as it gives palpitations specifically she experiences SVT's) and Scleroderma (Recent change in status such as improvement or worsening: no) since November 2021. Concomitant products included OMEPRAZOLE and ASCORBIC ACID, ERGOCALCIFEROL, NICOTINAMIDE, RETINOL, RIBOFLAVIN, THIAMINE HYDROCHLORIDE (VITAMINS [ASCORBIC ACID;ERGOCALCIFEROL;NICOTINAMIDE;RETINOL;RIBOFLAVIN;THIAMINE HYDROCHLORIDE]) for an unknown indication.   On 02-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 02-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Mar-2021, the patient experienced FEELING ABNORMAL (After 2nd dose, 15 hours after receiving the vaccine at 1 am in the morning she felt so bad), FEELING HOT (she felt so hot), DYSPNOEA (she had some difficulty breathing but not enough to go to the hospital) and PYREXIA (she had a slight reaction to the second dose with a 102°F temperature/her temperature was 102°F). In March 2021, the patient experienced MALAISE (feeling very sick). On 03-Mar-2021, FEELING ABNORMAL (After 2nd dose, 15 hours after receiving the vaccine at 1 am in the morning she felt so bad), FEELING HOT (she felt so hot), DYSPNOEA (she had some difficulty breathing but not enough to go to the hospital) and PYREXIA (she had a slight reaction to the second dose with a 102°F temperature/her temperature was 102°F) had resolved. At the time of the report, MALAISE (feeling very sick) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 02-Mar-2021, Body temperature: 102 degree Fahrenheit. On 02-Mar-2021, Heart rate: her pulse was 90.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   It was reported patient had a slight reaction to the second dose with a 102 degree Fahrenheit temperature and felt very sick within 15 hours of the administration.  Patient received Booster dose of Pfizer on 29 Oct 2021 with Batch number: 320308D, expiry date Feb 2022. The patient had never been diagnosed with tested positive for COVID-19. The event did not cause the patient to seek medical care. The patient experienced a similar event like it was a food related thing. Patient pulse was 90 but she went to sleep and during the morning she felt better. Patient did not had history of myocarditis or pericarditis. Patient mentioned she had a severe reaction with Pfizer booster and patient had to go to urgent care, but with Moderna it was only a slight reaction.  No treatment medications related with the primary series of Moderna vaccine.   Most recent FOLLOW-UP information incorporated above includes: On 05-Oct-2022: Live Follow-up  Significant information accepted: new events, concomitant medication, narrative updated and medical history updated.