One week later blood clot traveled to my brain; Major stroke; Brain heamorrahge/ Brain bleed; Now I am completely paralyzed on my left side/ Loosing arm and legs; I can't work, I can't even dress or bath myself/ Not able to dance; Pain/ Physical pain; Emotional trauma; This spontaneous case was reported by a consumer and describes the occurrence of THROMBOSIS (One week later blood clot traveled to my brain), CEREBROVASCULAR ACCIDENT (Major stroke), CEREBRAL HAEMORRHAGE (Brain heamorrahge/ Brain bleed) and PARALYSIS (Now I am completely paralyzed on my left side/ Loosing arm and legs) in a 47-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form and first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced THROMBOSIS (One week later blood clot traveled to my brain) (seriousness criterion medically significant), CEREBROVASCULAR ACCIDENT (Major stroke) (seriousness criterion medically significant) and CEREBRAL HAEMORRHAGE (Brain heamorrahge/ Brain bleed) (seriousness criterion medically significant). an unknown date, the patient experienced PARALYSIS (Now I am completely paralyzed on my left side/ Loosing arm and legs) (seriousness criterion medically significant), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I can't work, I can't even dress or bath myself/ Not able to dance), PAIN (Pain/ Physical pain) and EMOTIONAL DISORDER (Emotional trauma). At the time of the report, THROMBOSIS (One week later blood clot traveled to my brain) and CEREBROVASCULAR ACCIDENT (Major stroke) outcome was unknown and CEREBRAL HAEMORRHAGE (Brain heamorrahge/ Brain bleed), PARALYSIS (Now I am completely paralyzed on my left side/ Loosing arm and legs), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I can't work, I can't even dress or bath myself/ Not able to dance), PAIN (Pain/ Physical pain) and EMOTIONAL DISORDER (Emotional trauma) had not resolved.            No concomitant medication was provided. No treatment medication were provided.  One week after the booster dose, a blood clot travelled to patient's brain causing major stroke and brain hemorrhage. Currently, patient was completely paralyzed on left side and still had brain bleed. Patient could not work, dress or bathe by himself. Patient's personal life was disrupted as it stole patient's livelihood and drove patient's wife away. Patient had loosed a leg and arm, was unable to dance, unable to go fishing or pay the bills.  Patient was in physical pain as well as had emotional trauma thus wanted to settle all this quietly and out of the courts and media. Patient was hoping for fast resolution as well as healing.   Company Comment - This spontaneous case concerns a 47-year-old, male patient with no medical history reported, who experienced the unexpected, serious (medically significant) AESI of thrombosis, cerebrovascular accident and cerebral haemorrhage; the unexpected, serious (medically significant) event of paralysis; and other associated unexpected, non-serious events after administration of the booster dose of the Moderna mRNA-1273 vaccine on an unspecified date. The patient received both first and second doses of the Moderna mRNA-1273 vaccine (unspecified dates) and experienced very few side effects (unspecified adverse reactions). One week after administration of the booster dose, the patient had a blood clot in the brain which resulted in stroke and brain hemorrhage. Details regarding consultation/s, laboratory test/s and treatment were not provided. The patient stated that he is now completely paralyzed on his left side and still has a brain bleed. He also stated that he cannot work, dress or bathe himself. The patient also experienced physical pain and emotional trauma. The outcomes of the events thrombosis and cerebrovascular accident were unknown at the time of the report. The other events had not resolved at the time of the report. The benefit-risk relationship of the Moderna mRNA-1273 vaccine is not affected by this report. Further information has been requested.  This case was linked to MOD-2022-508849, MOD-2022-508838 (Patient Link).; Sender's Comments: This spontaneous case concerns a 47-year-old, male patient with no medical history reported, who experienced the unexpected, serious (medically significant) AESI of thrombosis, cerebrovascular accident and cerebral haemorrhage; the unexpected, serious (medically significant) event of paralysis; and other associated unexpected, non-serious events after administration of the booster dose of the Moderna mRNA-1273 vaccine on an unspecified date. The patient received both first and second doses of the Moderna mRNA-1273 vaccine (unspecified dates) and experienced very few side effects (unspecified adverse reactions). One week after administration of the booster dose, the patient had a blood clot in the brain which resulted in stroke and brain hemorrhage. Details regarding consultation/s, laboratory test/s and treatment were not provided. The patient stated that he is now completely paralyzed on his left side and still has a brain bleed. He also stated that he cannot work, dress or bathe himself. The patient also experienced physical pain and emotional trauma. The outcomes of the events thrombosis and cerebrovascular accident were unknown at the time of the report. The other events had not resolved at the time of the report. The benefit-risk relationship of the Moderna mRNA-1273 vaccine is not affected by this report. Further information has been requested.