After all the vaccines she was in pain.; Thought maybe she had itches from bugs or ticks or headlice or bed bugs /does not hurt just itchy; Not a bruise, but bloody round things; Pimples / thought they had acne; In the bed for 5 or 6 days; Rash; Kind of nasty; Welts are getting worse on back; Fatigue; This spontaneous case was reported by a patient and describes the occurrence of PAIN (After all the vaccines she was in pain.), PRURITUS (Thought maybe she had itches from bugs or ticks or headlice or bed bugs /does not hurt just itchy), ERYTHEMA (Not a bruise, but bloody round things), ACNE (Pimples / thought they had acne) and BEDRIDDEN (In the bed for 5 or 6 days) in a 78-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 057M21A, 012F21A, 029L20A and 012220A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     Previously administered products included for Product used for unknown indication: SHINGRIX (Second shingles shot.) in 2022 and SHINGRIX (First shingles shot.). Past adverse reactions to the above products included No adverse event with SHINGRIX and SHINGRIX. Concurrent medical conditions included Anxiety, Night terrors, Dry eyes, Pollen allergy (Outdoor allergies pollen), Allergy to plants (Allergy to pine trees), Thyroid disorder (For 25 years) and Gluten free diet (Patient try to be gluten free and does not eat alot of things.). Concomitant products included CETIRIZINE HYDROCHLORIDE (ALLERGY RELIEF [CETIRIZINE HYDROCHLORIDE]) for Allergy NOS, SERTRALINE HYDROCHLORIDE (ZOLOFT) for Anxiety, APIXABAN (ELIQUIS) for Blood pressure high, CICLOSPORIN (RESTASIS) for Dry eyes, CLONAZEPAM for Night terrors, LEVOTHYROXINE for Thyroid disorder, ALIROCUMAB (PRALUENT), EZETIMIBE, METOPROLOL SUCCINATE and MULTIVITAMIN [VITAMINS NOS] for an unknown indication.   On 18-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 16-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 25-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PAIN (After all the vaccines she was in pain.), PRURITUS (Thought maybe she had itches from bugs or ticks or headlice or bed bugs /does not hurt just itchy), ERYTHEMA (Not a bruise, but bloody round things), ACNE (Pimples / thought they had acne), BEDRIDDEN (In the bed for 5 or 6 days), RASH (Rash), FEELING ABNORMAL (Kind of nasty), URTICARIA (Welts are getting worse on back) and FATIGUE (Fatigue). The patient was treated with TRIAMCINOLONE ACETONIDE at a dose of Cream 0.1 % and gone through like 3 tubes from that. At the time of the report, PAIN (After all the vaccines she was in pain.), PRURITUS (Thought maybe she had itches from bugs or ticks or headlice or bed bugs /does not hurt just itchy), ERYTHEMA (Not a bruise, but bloody round things), ACNE (Pimples / thought they had acne), RASH (Rash), FEELING ABNORMAL (Kind of nasty), URTICARIA (Welts are getting worse on back) and FATIGUE (Fatigue) outcome was unknown and BEDRIDDEN (In the bed for 5 or 6 days) had resolved.            Concomitant medication included Fish gel pills and Centrum vitamins.   It was reported that after the last shot, caller went to see patient's son in April, Double masked, didn't really go anywhere. Patient said the dermatologist did a big blood test and they called some days later and says they were awful and they freaked out but her doctor says they are not that concerned. she said that they need some direction and this is not normal. Patient thinks maybe it has something to do with their immune system.  Patient reported that she took nothing after the side effects beside the cream from the dermatologist.   This case was linked to MOD-2022-629221, MOD-2022-629244.   Most recent FOLLOW-UP information incorporated above includes: On 15-Aug-2022: Follow up received contains non new information.