Very depressed; Her periods were regular, but starting 12May2021/She bleed for 43 days straight; She began to experience hard and hurtful nipples; She began to experience hard and hurtful nipples; Chills; Fever; Body aches; Hot and cold; Frustration; Bleeding problem; Her left arm had doubled up in size, it was super hot and red; Her left arm had doubled up in size, it was super hot and red; Her left arm had doubled up in size, it was super hot and red/ She felt her arm and felt like she could fry and egg on her arm, it was burning so bad; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 35 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 29Apr2021 18:00 (Lot number: EW0164) at the age of 35 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Depression" (unspecified if ongoing), notes: I have been dealing with depression my whole life, but this whole past year; "Headache" (unspecified if ongoing); "Anxiety" (unspecified if ongoing); "Premenstrual dystrophic disorder" (unspecified if ongoing), notes: Premenstrual dystrophic disorder; "Constipation", start date: 2021 (unspecified if ongoing). Concomitant medication(s) included: PROPANOLOL [PROPRANOLOL] taken for headache (ongoing); STRATTERA taken for depression, anxiety (ongoing); PROZAC taken for anxiety, premenstrual dysphoric disorder, start date: Jan2021 (ongoing). Vaccination history included: Bnt162b2 (Dose: 1, Lot: EW0158, Administered in left arm), administration date: 08Apr2021, when the patient was 35 years old, for COVID-19 Immunization. The following information was reported: HAEMORRHAGE (medically significant) with onset 2021, outcome "unknown", described as "Bleeding problem"; PERIPHERAL SWELLING (medically significant), ERYTHEMA (medically significant) all with onset 2021, outcome "unknown" and all described as "Her left arm had doubled up in size, it was super hot and red"; FEELING HOT (medically significant) with onset 2021, outcome "unknown", described as "Her left arm had doubled up in size, it was super hot and red/ She felt her arm and felt like she could fry and egg on her arm, it was burning so bad"; HEAVY MENSTRUAL BLEEDING (medically significant) with onset 12May2021, outcome "not recovered", described as "Her periods were regular, but starting 12May2021/She bleed for 43 days straight"; NIPPLE DISORDER (non-serious), NIPPLE PAIN (non-serious) all with onset 30Apr2021, outcome "not recovered" and all described as "She began to experience hard and hurtful nipples"; CHILLS (non-serious) with onset 30Apr2021, outcome "not recovered", described as "Chills"; DEPRESSION (non-serious), outcome "unknown", described as "Very depressed"; FRUSTRATION TOLERANCE DECREASED (non-serious) with onset 2021, outcome "unknown", described as "Frustration"; PYREXIA (non-serious) with onset 30Apr2021, outcome "unknown", described as "Fever"; PAIN (non-serious) with onset 30Apr2021, outcome "unknown", described as "Body aches"; FEELING OF BODY TEMPERATURE CHANGE (non-serious) with onset 2021, outcome "unknown", described as "Hot and cold". The patient underwent the following laboratory tests and procedures: computerised tomogram: (2021) unknown results; mammogram: (Nov2021) it showed no cancer. Therapeutic measures were taken as a result of peripheral swelling, erythema, feeling hot, heavy menstrual bleeding. One day after she began to experience hard and hurtful nipples, on and off since, at least once week. Caller states "sometimes I get chills with it, and sometimes she gets chills that does not accompany the pain in the nipples" nipples hard and hurt on and and off, accompanied with chills.The bleeding problem, because, I've been going and they have tried other stuff to try to help me, but nothing is really helping. They told me that sometimes women just bleed. She has been dealing with depression my whole life, but this whole past year, and all this stuff, has honestly made me not want to live, and she really regrets now getting the vaccine, she feels completely broken by it. She missed my nephews graduation, because she was bleeding so much, she could not travel. She has seen so many therapist. They say if we try this option or that option it may lead to a hysterectomy. If the male reproductive system was affected, something would have been done" Patient wanted to reported and express my frustration". Caller comes across very depressed, and has a history of depression. After the second shot she broke down with fever, chills, and body aches like a lot of people were reporting. However, the weird symptoms that mixed in with it was her nipples would get hard and hurt which hits her at times since then. She did not keep track of the fever. She got the vaccine on 29Apr2021, and Friday 30Apr2021 she started to feel like had fever and chills. She would be hot and cold, Hot and cold, she would have body aches all over and she could not get out of work.She initially stated this lasted up through that Monday. However, that Sunday she was in Facility (assessed as emergency room equivalent) because Her left arm had doubled up in size, it was super hot and red. She felt her arm and felt like she could fry and egg on her arm, it was burning so bad. While in Facility she was given antibiotics. Nipples hard and hurt: This has been going on and off. It would happen at least once a week and it would last half an hour where she would have to deal with the pain. It hits every now and then during the week. Before this her periods were regular, but starting 12May2021  she started to have issues. She bled for 43 days straight until she had a D&C sometime in Jun2021 or Jul2021. It got to the point it was so heavy and hindering her a lot from doing stuff. She tried to go somewhere for an hour and bled through everything she had on for protection. She commented she is still having irregular bleeding after the D&C. She has been trying different birth control methods. She commented her anxiety gets worse during "that time of the month" and they thought this would help. It did help, but then that time of the month never ended .  She stated she thinks the generic prozac is called Fluoxetine. Investigations: Feb2021 or Mar2021- Had constipation, had a CAT Scan. She thinks her doctor's overreacted and all she needed was laxatives. At first they thought she had a cyst. Soon as had laxatives everything was fine. After the shot they did D&C, they had a camera up there checking things. Mammogram Nov2021- all knows it showed no cancer. Vaccination Facility Type: City State Department.No Additional Vaccines Administered on Same Date of the Pfizer Suspect. She normally sees her doctor every couple months due to depression. She was always in contact with primary care already. However, her OB-GYN was contacted in Jun because she was bleeding was getting too much. No Prior Vaccinations (within 4 weeks). At end of call, caller mentioned her nipples getting hard and hurting is associated with cold chills she is still having which is off an on.