Hives on face, neck, shoulder the size of golf balls; Itching; Red marks; This is a spontaneous report from a contactable consumer or other non-healthcare professional (patient). A 56-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection, Lot Number: EW0162), via an unspecified route of administration, administered in Arm Left on 26Apr2021 at 11:30 (age at the time of vaccination was 56 years) as DOSE 2, SINGLE for covid-19 immunisation. The patient medical history (including any illness at time of vaccination) and concomitant medications were not reported. Historically, the patient had received (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection, lot number: ER8727) via an unspecified route of administration as an injection in left arm on 07Apr2021 (age at the time of vaccination was 56 years) as dose 1, single for covid-19 immunization. History of all previous immunization with the Pfizer vaccine considered as suspect were reported as none. The patient did not experience any AE(s) following prior vaccinations. On an unspecified date in 2021, the patient experienced red marks. On 26Apr2021, the patient experienced hives on face, neck, shoulder the size of golf balls and itching. Reportedly, the second shot was last Monday, she was fine in the day, but around midnight her face, neck, and shoulder had hives the size of golf balls. The patient phoned her physician and was told there was something in the vaccine that caused this and was advised to call Pfizer. The patient reported about her weight and added she was too fat. The patient switched her doctor after he retired, about a year and a half ago. Her original doctor was a child was located near the house, she didn't like the new doctor who replaced him, and she switched to her husband's doctor. The hives started the evening of the second dose, but the itching stopped, and they were not as big and gross, red marks can still be seen. The patient(s) doctor advised it may last 10-14 days and has had people call who had hives from this as well. Her medications were not related to this event or she would get hives every day. The patient(s) sister was a nurse for many years and told the patient she thinks that the reaction was probably caused by a polymer chemical in the vaccine that they don't usually put in other vaccines. It was added to the vaccine to keep it medically connected via the chemical structure, to a person's body. She just called her physician's office because they preferred that. Reportedly, she did fine with the 1st vaccine. Reporter seriousness for hives on face, neck, shoulder the size of golf balls was unspecified. The any AE(s) did not require a visit to Emergency Room or Physician Office. This report was not related to a study or programme. Investigation assessment and relevant tests was reported as no. No additional vaccines administered on same date of the Pfizer suspect. The outcome of the red marks event was unknown. The outcome of the event itching was recovered on an unspecified date in 2021. The outcome of the event hives on face, neck, shoulder the size of golf balls was recovering.  No follow-up attempts are needed. No further information is expected.