solar urticaria/ breaks out in hives and itches/ itches are bad; pregnancy after vaccination; COVID arm 2nd dose; This spontaneous prospective pregnancy case was reported by a patient and describes the occurrence of SOLAR URTICARIA (solar urticaria/ breaks out in hives and itches/ itches are bad), VACCINATION SITE REACTION (COVID arm 2nd dose) and MATERNAL EXPOSURE BEFORE PREGNANCY (pregnancy after vaccination) in a 34-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     No Medical History information was reported.    On 25-Aug-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. The patient's last menstrual period was on an unknown date and the estimated date of delivery was 07-Sep-2022. In 2021, the patient experienced VACCINATION SITE REACTION (COVID arm 2nd dose). On 25-Aug-2021, the patient experienced MATERNAL EXPOSURE BEFORE PREGNANCY (pregnancy after vaccination). In September 2021, the patient experienced SOLAR URTICARIA (solar urticaria/ breaks out in hives and itches/ itches are bad). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) at an unspecified dose and frequency and CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) at an unspecified dose and frequency. On 25-Aug-2021, MATERNAL EXPOSURE BEFORE PREGNANCY (pregnancy after vaccination) had resolved. At the time of the report, SOLAR URTICARIA (solar urticaria/ breaks out in hives and itches/ itches are bad) and VACCINATION SITE REACTION (COVID arm 2nd dose) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In January 2022, Pregnancy test: (Positive) Positive.         Patient was not on any concomitant medication. Patient reported to have developed solar urticaria after second dose of the Moderna COVID-19 vaccine on 25-Aug-2021. Shortly after, in Sep-2021, patient was diagnosed with solar urticaria. Patient could not go in the sun as the patient broke out in hives and itches. The itch was bad. Patient's allergist said there was no cure, nothing could be done for the solar urticaria. Patient reported to be pregnant. Patient was not pregnant when received the first 2 doses of the vaccine. The last menstrual period was noted as 06-Dec-2021. The batch or lot number and expiration date for second dose was unknown. Additional treatment reported was 100 proof sunscreen.  Company comment: This spontaneous prospective pregnancy case reported by a patient, concerns a 34 year old female patient, with no relevant medical history reported, who experienced the unexpected, non-serious events of Solar Urticaria ((solar urticaria/ breaks out in hives and itches/ itches are bad), Vaccination site reaction ( COVID arm 2nd dose) unknown days after receiving the 2 dose of mRNA1273 vaccine in the covid 19 vaccination series. Patient was reported to have developed solar urticaria after second dose of the Moderna COVID-19 vaccine on 25-Aug-2021. Shortly after, in Sep-2021, patient was diagnosed with solar urticaria. The patient was treated with diphenhydramine hydrochloride, cetirizine hydrochloride and 100 proof sunscreen. In January 2022, Pregnancy test was Positive. Patient was not pregnant when she received the first 2 doses of the vaccine. The last menstrual period was noted as 06-Dec-2021 and the estimated date of delivery was 07-Sep-2022. Maternal Exposure Before pregnancy (pregnancy after vaccination) was reported. Outcome of solar urticaria and vaccination site reaction was unknown. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-608572 (Patient Link).; Sender's Comments: This spontaneous prospective pregnancy case reported by a patient, concerns a 34 year old female patient, with no relevant medical history reported, who experienced the unexpected, non-serious events of Solar Urticaria ((solar urticaria/ breaks out in hives and itches/ itches are bad), Vaccination site reaction ( COVID arm 2nd dose) unknown days after receiving the 2 dose of mRNA1273 vaccine in the covid 19 vaccination series. Patient was reported to have developed solar urticaria after second dose of the Moderna COVID-19 vaccine on 25-Aug-2021. Shortly after, in Sep-2021, patient was diagnosed with solar urticaria. The patient was treated with diphenhydramine hydrochloride, cetirizine hydrochloride and 100 proof sunscreen. In January 2022, Pregnancy test was Positive. Patient was not pregnant when she received the first 2 doses of the vaccine. The last menstrual period was noted as 06-Dec-2021 and the estimated date of delivery was 07-Sep-2022. Maternal Exposure Before pregnancy (pregnancy after vaccination) was reported. Outcome of solar urticaria and vaccination site reaction was unknown. The benefit-risk relationship of mRNA-1273 is not affected by this report.