Hard time walking from bedroom to living room; Losing weight, about 15 pounds; fatigue is not going away/exhausted/fatigue and pain are lingering; extreme pain/pain/got worse and worse/chronic pain is exacerbated/pain was excruciating//it was like experiencing all the pain all at once for the first time/fatigue and pain are lingering; This spontaneous case was reported by a consumer and describes the occurrence of FATIGUE (fatigue is not going away/exhausted/fatigue and pain are lingering), PAIN (extreme pain/pain/got worse and worse/chronic pain is exacerbated/pain was excruciating//it was like experiencing all the pain all at once for the first time/fatigue and pain are lingering), GAIT DISTURBANCE (Hard time walking from bedroom to living room) and ABNORMAL LOSS OF WEIGHT (Losing weight, about 15 pounds) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 058H21A, 046B21A and 019B21A) for COVID-19 vaccination.     Concurrent medical conditions included Drug allergy (Codeine Allergy), Parkinson's disease and Chronic pain.   On 27-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 23-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In December 2021, the patient experienced FATIGUE (fatigue is not going away/exhausted/fatigue and pain are lingering) and PAIN (extreme pain/pain/got worse and worse/chronic pain is exacerbated/pain was excruciating//it was like experiencing all the pain all at once for the first time/fatigue and pain are lingering). On an unknown date, the patient experienced GAIT DISTURBANCE (Hard time walking from bedroom to living room) and ABNORMAL LOSS OF WEIGHT (Losing weight, about 15 pounds). At the time of the report, FATIGUE (fatigue is not going away/exhausted/fatigue and pain are lingering), PAIN (extreme pain/pain/got worse and worse/chronic pain is exacerbated/pain was excruciating//it was like experiencing all the pain all at once for the first time/fatigue and pain are lingering) and GAIT DISTURBANCE (Hard time walking from bedroom to living room) had not resolved and ABNORMAL LOSS OF WEIGHT (Losing weight, about 15 pounds) outcome was unknown.            No concomitant medications were mentioned.  After the Moderna booster, patient had an immediate reaction. Her breathing was ok. Patient did not went to the emergency room because patient did not thought she was dying. Patient was still exhausted from her reaction and it has been months. The fatigue was not going away. It takes her one whole day to do one thing that she used to do in one hour. She is not herself anymore. She was trying to take vitamins, exercise, and eat properly. She does not know what to do. She was not necessarily dieting.She used to walk a good amount of miles, but now she has a hard time walking from the bedroom to the living room.  No treatment details were reported.   This case was linked to MOD-2022-521969, MOD-2022-522741 (Patient Link).