she experienced swelling in the site of injection; feeling warm; itchy; she did have a headache; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  An 80-year-old female patient received BNT162b2 (BNT162B2), on 02Sep2021 at 14:30 as dose 3 (booster), single (Lot number: FC3184) at the age of 80 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "aortic valve replacement", start date: 02Mar2015 (unspecified if ongoing), notes: an aortic valve replacement since 2015.; "Mantle cell lymphoma" (unspecified if ongoing), notes: Mantle cell lymphoma in remission for 5 years, she has had 2 cancers; "Colon cancer" (unspecified if ongoing), notes: Colon cancer in remission for 5 years. There were no concomitant medications. Vaccination history included: BNT162b2 (Dose:1, Lot: EL9261, Route: left upper arm), administration date: 23Jan2021, when the patient was 80-year-old, for Covid-19 Immunization, reaction(s): "headache with all the vaccines"; BNT162b2 (Dose:2, Lot: EM9809, Route: left upper arm), administration date: 13Feb2021, when the patient was 80-year-old, for Covid-19 Immunization, reaction(s): "headache with all the vaccines". The following information was reported: FEELING HOT (non-serious) with onset 03Sep2021, outcome "recovering", described as "feeling warm"; PRURITUS (non-serious) with onset 03Sep2021, outcome "recovering", described as "itchy"; VACCINATION SITE SWELLING (non-serious) with onset 03Sep2021, outcome "recovering", described as "she experienced swelling in the site of injection"; HEADACHE (non-serious) with onset Sep2021, outcome "recovering", described as "she did have a headache". The patient underwent the following laboratory tests and procedures: Blood test: Unknown Results, notes got blood work done. Therapeutic measures were not taken as a result of vaccination site swelling, feeling hot, pruritus, headache.  Additional Information: Caller shared the experience she had from her Booster dose in 02Sep2021; she stated that she experienced swelling in the site of injection, that later advanced to above the elbow feeling warm and itchy. telling the caller that swelling in injection site and muscle pain were reported adverse reactions. Is report related to a study or programme? No. HCP Type: Physician assistant. Adds that she got the booster on 02Sep2021, and it started getting better after 5-6 days, wants to know if she should get another shot but wanted to check to be sore. Age: caller is 81 years old, but the event happened when she was 80 years old. Caller adds that she has been very blessed, she has had 2 cancers and an aortic valve replacement since 2015. Event: States she got the shot 02Sep2021 and the next day her arm swelled up from the injection site to her elbow. It was warm and itchy; she didn't get a fever or anything like that and it didn't bother her so she didn't take her temperature. Also states she did have a headache and that was the only other thing. States that she had no reaction with the first or second vaccine but did have a headache with all the vaccines. Didn't know if maybe she got an infection at the swelling site or what. Treatment: no treatment, just put ice on it and called the pharmacist at withheld and talked to her and by the time the caller talked to the pharmacist she states it went back down otherwise the pharmacist would have been worried. States it only lasted 5-6 days. adds that her son had a lung transplant, and he is 61 years old. Investigations: States when she went and got blood work done, the person taking her blood said it looked like a severe reaction, it didn't hurt, and she didn't get sick, so she just let it go and it went back down. She got the vaccine at 2:30pm and the next morning is when she got up and it started to swell up, and it was itchy and warm. Additional Information: Physician office: no Emergency room: no. Prior Vaccinations (within 4 weeks): no. AE(s) following prior vaccinations: no. Family Medical History: Her daughter is diabetic; her other daughter had an aortic valve replacement and her sister. And her son had a lung transplant from COPD. and her husband had lung cancer, he passed away, states she had him for 56 years, so she has to look at things that way. Relevant Tests: no