migraine with flashes of light in left eye; migraine with flashes of light in left eye; gets IBS stuff; has had diarrhea; diarrhea, had a mild version of the diarrhea that seemed to get worse after the vaccine and still ongoing; vessels in hands really dilated and dark blue; This is a spontaneous report from a contactable consumer (patient). A 66-year-old female patient received the first dose BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; Lot number EL9264), via an unspecified route of administration (arm left) on 30Jan2021 14:00 at SINGLE DOSE for to have some protection against COVID, at 66 years old. Medical history included connective tissue disorder and anti-cardiac lipid antibody problem; she is prone to blood clots from 2001. At that time, she was sent to the hospital and no one could figure out what it was. She was seeing the Rheumatologist and another person, and they knew something was going on and was given Prednisone (from 2001) because her tissues in the joints were swelling and she had trouble with speech. Patient also reported this as some weird connective tissue disorders already and some anti-cardiac lipid antibody problem. It was really weird and had not changed a bit since so she was kind of checking to see if anyone has reported anything like this. She reported that with this weird antibody problem, she is more prone to blood clots and has to be careful with medications with her blood she knows that some breast cancer medicines can do that. She stated this immune thing was never diagnosed. She also had migraine with globes of flashes of light, left eye (does not typically get migraines and has only had 1 in her life and she saw globes of lights in both eyes and had to go to the emergency room and was told it was an ocular migraine and this was also only in the left eye. This was long ago) from an unspecified date.  Concomitant medication included low dose steroid (unspecified). The patient previously received flu vaccine on Sep2020 (AE none). No other vaccines were administered on the same day. On 30Jan2021, the patient experienced vessels in hands were really dilated and dark blue 5 hours after vaccination. On 30Jan2021, the patient also experienced IBS stuff and has had diarrhea the last couple of days after getting the COVID vaccine. She took Pepto Bismol to help and had a mild version of the diarrhea that seemed to get worse after the vaccine and still ongoing. On 01Feb2021, the patient experienced migraine with flashes of light in left eye. It was further described as having a weird migraine with flashes of light in the left eye and she got the shot in her left arm and not sure if that makes any difference. She does not typically get migraines and has only had 1 in her life. The migraines started in the morning and lasted about an hour (as reported) and now they are gone and hopes they stay gone (reported as recovering). She wanted to know if she can take TYLENOL or ibuprofen for vaccine. She heard about people getting symptoms after the second dose not the first dose. Events did not require visits to the emergency room or physician office, but stated that if her vision become worse, she would go to the eye infirmary close by. The outcome of the events diarrhea and vessels in hands really dilated and dark blue, gets IBS stuff was not recovered. Outcome of the events migraine with flashes of light in left eye was reported as recovering.