complete numbness to right side; Body aches; Left side paralysis; painful joints; stiff joint; weakness in limbs; Soreness at injection site; This spontaneous case was reported by a consumer and describes the occurrence of HEMIPLEGIA (Left side paralysis) and HEMIANAESTHESIA (complete numbness to right side) in a 36-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Drug allergy (Tecfidera), Multiple sclerosis (No new lesions or growth in brain between last year's MRI and this year's MRI.), Depression, Anxiety, Pain and Post-traumatic stress disorder. Concomitant products included HYDROXYZINE for Anxiety, BUPROPION for Depression, FINGOLIMOD HYDROCHLORIDE (GILENYA) for Multiple sclerosis, GABAPENTIN for Pain, PRAZOSIN for Post-traumatic stress disorder.   On 29-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 04-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Mar-2021, the patient experienced VACCINATION SITE PAIN (Soreness at injection site). On 30-Mar-2021, the patient experienced JOINT STIFFNESS (stiff joint), MUSCULAR WEAKNESS (weakness in limbs) and ARTHRALGIA (painful joints). On 31-Mar-2021, the patient experienced HEMIPLEGIA (Left side paralysis) (seriousness criterion medically significant). On an unknown date, the patient experienced HEMIANAESTHESIA (complete numbness to right side) (seriousness criterion medically significant) and MYALGIA (Body aches). On 02-Apr-2021, HEMIPLEGIA (Left side paralysis) had resolved. At the time of the report, HEMIANAESTHESIA (complete numbness to right side), JOINT STIFFNESS (stiff joint), MUSCULAR WEAKNESS (weakness in limbs), MYALGIA (Body aches), ARTHRALGIA (painful joints) and VACCINATION SITE PAIN (Soreness at injection site) had resolved.            The patient pushed through and did stretches throughout day to try and keep from locking up joints. On 31-Mar-2021, the patient woke to right side feeling normal but left side unwilling to function. Left hand would not enclose and right arm would not raise when desired. Left leg would not tolerate weight and foot had to be watched for footing placement when trying to move. She forced self to move and do things even though exhaustion came quicker. On 01-Apr-2021, she regained function of left side ligaments but was still heavily fatigued. On 02-Apr-2021, symptoms weren't present and those that were, did not effect daily functions.   It was reported that it took 1.5 days for body aches and joint pain to resolve and several days for right side numbness to resolve.  No treatment information was reported.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Medical history of multiple sclerosis may confound causality.   This case was linked to MOD-2021-265442 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 23-Jul-2021: Significant follow up contains updated reporter address, patient demographics, patient history, first and second dose vaccine date and anatomical location, concomitant medications, new events (Paralysis, Musculoskeletal stiffness, Asthenia, Vaccination site pain) added and case upgraded to serious.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Medical history of multiple sclerosis may confound causality.