pre-syncope; Blood pressure continued to go up and down uncontrollably (up to 175/96); partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg; partial numbness right hand; partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg; Blood pressure went up (145/104)/ uncontrollably (up to 175/96); Loosing consciousness; Chest pain; Tightness; Dose number=3; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the parent. A 19-year-old male patient received bnt162b2 (BNT162B2), administered in arm left, administration date 29Dec2021 (Lot number: 3303680) at the age of 19 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Known allergies: lactose intolerant" (unspecified if ongoing).  Concomitant medication(s) included: HPV VACCINE, administration date 23Nov2021. Vaccination history included: Bnt162b2 (Dose Number: 2, Batch/Lot No: ER8736, Location of injection: Arm Left), administration date: 09May2021, when the patient was 18 years old, for COVID-19 immunization; Bnt162b2 (Dose Number: 1, Batch/Lot No: PW1061, Location of injection: Arm Left), administration date: 18Apr2021, when the patient was 18 years old, for COVID-19 immunization. The following information was reported: IMMUNISATION (medically significant) with onset 29Dec2021, outcome "unknown", described as "Dose number=3"; LOSS OF CONSCIOUSNESS (medically significant) with onset 31Dec2021, outcome "not recovered", described as "Loosing consciousness"; PRESYNCOPE (medically significant), outcome "unknown", described as "pre-syncope"; CHEST PAIN (medically significant) with onset 30Dec2021 08:00, outcome "recovered", described as "Chest pain"; CHEST DISCOMFORT (medically significant) with onset 30Dec2021 08:00, outcome "recovered", described as "Tightness"; HYPERTENSION (medically significant) with onset 31Dec2021, outcome "not recovered", described as "Blood pressure went up (145/104)/ uncontrollably (up to 175/96)"; BLOOD PRESSURE FLUCTUATION (medically significant), outcome "unknown", described as "Blood pressure continued to go up and down uncontrollably (up to 175/96)"; HYPOAESTHESIA (medically significant) with onset 04Jan2022, outcome "not recovered", described as "partial numbness right hand; partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg "; BURNING SENSATION (medically significant) with onset 06Jan2022, outcome "not recovered", described as "partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg". The events "loosing consciousness", "chest pain", "tightness", "blood pressure went up (145/104)/ uncontrollably (up to 175/96)", "partial numbness right hand; partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg " and "partial numbness/burning sensation left hand, right leg & left side face/ partial numbness entire face & left leg" were evaluated at the physician office visit and emergency room visit. The event "pre-syncope" was evaluated at the emergency room visit. The patient underwent the following laboratory tests and procedures: blood glucose: (unspecified date) around 119, notes: Morning fasting sugar is now always around 119; (unspecified date) normal; blood pressure measurement: (unspecified date) 175/96, notes: continued to go up and down uncontrollably; (31Dec2021) 145/104, notes: went up; blood test: (unspecified date) normal; electrocardiogram: (unspecified date) normal; fibrin d dimer: (unspecified date) normal; sars-cov-2 test: (01Jan2022) negative, notes: Nasal Swab; troponin: (unspecified date) normal; ultrasound scan: (unspecified date) no liquid in pericardium. Therapeutic measures were taken as a result of loss of consciousness, chest pain, chest discomfort, hypertension, blood pressure fluctuation, hypoaesthesia, burning sensation. Clinical course: The consumer reported her son began having chest pain and tightness next day after booster. This continued for two days. Took ibuprofen. Day 3- blood pressure went up (145/104) and he began  loosing consciousness. This pre-syncope state continued non-stop for 3 days. Two trips to emergency on 01Jan2022 and 03Jan2022. Blood work normal on both days. Troponins normal, ECG normal, D-dimer normal, heart ultrasound showed no liquid in pericardium. Blood pressure continued to go up and down uncontrollably (up to 175/96). Sugar (non-fasting) normal - did not correlate with pre-syncope. Morning fasting sugar is now always around 119. After a virtual visit w/ family physician on Day 5, withheld began taking acetaminophen (650 mg/day), losartan (25mg) and hydroxyzine (25 mg). On Day 7, withheld developed partial numbness in his right hand; Day 9 - partial numbness/burning sensation in left hand, right leg and left side of the face. Day 10 he started methylprednisolone (MEDROL) dosepak 6 day course. Day 11 patient had partial numbness of entire face and left leg.  The patient did not receive any other medication within 2 weeks of vaccination. Prior to the vaccination, the patient was not diagnosed with COVID-19.  It was also reported that since the vaccination, the patient had been tested for COVID-19.