Interacted in a very weird way with my permanent medicines that I take; Making me very groggy in the morning and tired during the day; Making me very groggy in the morning and tired during the day/Tiredness; I was losing all my energy/Drained me, it interacted/little energy left; Could barely move around; Body hurt all over; hangover; This is a spontaneous report from a contactable consumer (patient). A female patient of an unspecified age received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number and expiration date not provided), 1st dose via an unspecified route of administration on an unspecified date as a single dose for covid-19 immunisation; trazodone; clozapine; clonazepam, all via an unspecified route, date, dose for psychiatric disorder prophylaxis; atenolol via an unspecified route, date, dose for blood pressure measurement; omeprazole via an unspecified route, date, dose for gastrooesophageal reflux disease.  Medical history included ongoing hypertension, schizoaffective disorder bipolar type, psychiatric condition. The patient's concomitant medications were not reported. The patient experienced 'interacted in a very weird way with my permanent medicines that i take, making me very groggy in the morning and tired during the day, making me very groggy in the morning and tired during the day/tiredness, i was losing all my energy/drained me, it interacted/little energy left, could barely move around, body hurt all over, hangover', all on an unspecified date. The action taken in response to the events for trazodone, clozapine, clonazepam, atenolol, omeprazole, all was unknown. The outcome of the events was unknown.  Clinical course: Consumer stated, "Is this the Pfizer or is it the National Covid hotline? 15Apr. I took a Covid vaccine shot (Confirmed as Pfizer Covid-19 Vaccine) at (facility name and city) and I believe it interacted in a very weird way with my permanent medicines that I take. The permanent medicine that I have to take every day, it has the side effects of making me very groggy in the morning and tired during the day somewhat, and for the last 5 week I thought I was going to die with fatigue, I felt like my entire, all the flesh in my arms, my back and my legs just felt like I was dying. Like I was  losing all my energy. My energy felt like I was gone and I have been sitting around like an old lady for 5 weeks wondering I was going to live or die basically. I wondered that what was going on and today was first day I felt better since 5 weeks and when I told my son about it two or three weeks ago. He said do not you ever take the other shot, mom there is something wrong. I am just telling you it just interfered with my medicines that I take from my doctor, my psychiatrist, my psychiatric medicines. And I felt like I was going to, I did not know whether I was going to live or die because how it drained me, it interacted. What it did, was it caused the side effects of my psychiatric medicines to be I do not know how many times worse. I should have never taken that shot. I am just saying this because I am hoping that this will go on record and the people will be careful with asking people about the type of medication that they take before they get the shot. The medications that I take one is called Trazodone, the other medication that I take is called Clozapine and the other one I take is called Clonazepam and those three medications are my psychiatric medications that I take everyday and I think I could have died from it. You should be glad may be somebody can help someone. It is just recorded it should be talked about." Product details of Trazodone, Clozapine and Clonazepam(LOT# and Expiration date): Consumer stated, "I take them every single day. I have been taking the same one's for years. I get a one month refill every year, every month. I do not know what the LOT# means. I have a Rx number." Consumer stated, "I probably should also tell you that I also take Atenolol for my blood pressure, I take Omeprazole for GERD. Do you know what that is GERD ? Regurgitating indigestion?" Product details (LOT# and Expiration date) of and Omeprazole: Consumer stated, "I do not know what a LOT# is. I do not understand what you mean by that? I have the Rx number. It has a number that is NDC(further not clarified). What else do you need." Product details of Atenolol(LOT# and Expiration date):Consumer stated, "I do not know what a LOT# is? All I have is a Rx number. I do not know what LOT# means. I do not see any other number on this." Other medical conditions: Consumer stated, "I have hypertension, I have a psychiatric condition, I have Schizoaffective disorder bipolar type they say." When confirmed vaccine as Pfizer Covid 19 vaccine: Consumer stated, "Correct, the first shot." Start date of event: Consumer stated, "5 weeks ago, after I had the shot. I had it for 5 weeks." Treatment: Consumer stated, " I did not realize, I should because I tell you why because my psychiatric medications that I take caused extreme tiredness. At night I go to sleep with these psychiatric medicines I wake up in the morning, I feel like I have a hangover from fatigue. I feel I have fatigue now that is normal for me. But after I had the shot I had so little energy left that I was going to die. I could barely move around. My body hurt all over, I hurt all over. I think it was. Today I started to feel better. It has taken a long time."  Information on the lot/batch number has been requested.