lightning bolt pain 2x on left side of head on left temple; Shot in head or lighting bolt strike 3 times in a row at right temple; States this was so painful that her body jerked so hard she lifted out of seat of car; States this was so painful that her body jerked so hard she lifted out of seat of car; Micro or mini strokes; 2 minutes after receiving the 1st dose patient had anaphylactic reaction; This spontaneous case was reported by a consumer and describes the occurrence of CEREBROVASCULAR ACCIDENT (Micro or mini strokes) and ANAPHYLACTIC REACTION (2 minutes after receiving the 1st dose patient had anaphylactic reaction) in a 56-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 020B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 and Headache (Had headaches prior to vaccine and prior MRIs.). Concomitant products included MULTIVITAMINS [VITAMINS NOS], DULOXETINE HYDROCHLORIDE (CYMBALTA) and QUETIAPINE for an unknown indication.    On 09-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 09-Apr-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced ANAPHYLACTIC REACTION (2 minutes after receiving the 1st dose patient had anaphylactic reaction) (seriousness criterion medically significant). On 13-Apr-2021, the patient experienced CEREBROVASCULAR ACCIDENT (Micro or mini strokes) (seriousness criterion medically significant), PAIN (States this was so painful that her body jerked so hard she lifted out of seat of car) and DYSKINESIA (States this was so painful that her body jerked so hard she lifted out of seat of car). On 16-Apr-2021, the patient experienced HEAD DISCOMFORT (lightning bolt pain 2x on left side of head on left temple) and HEADACHE (Shot in head or lighting bolt strike 3 times in a row at right temple). The patient was treated with TOPIRAMATE (TOPAMAX) for Adverse event, at an unspecified dose and frequency. At the time of the report, CEREBROVASCULAR ACCIDENT (Micro or mini strokes), ANAPHYLACTIC REACTION (2 minutes after receiving the 1st dose patient had anaphylactic reaction), HEAD DISCOMFORT (lightning bolt pain 2x on left side of head on left temple), PAIN (States this was so painful that her body jerked so hard she lifted out of seat of car) and DYSKINESIA (States this was so painful that her body jerked so hard she lifted out of seat of car) outcome was unknown and HEADACHE (Shot in head or lighting bolt strike 3 times in a row at right temple) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Magnetic resonance imaging: abnormal (abnormal) MRIs were done that showed she had more damage after the vaccine..     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant medication reported included centrum silver. Patient stated she reported to VAERS herself on 14-Jul-2021. Five days after the first dose she had micro or mini strokes and felt like she was shot in head or lighting bolt strikes 3 times in a row at right temple. Three days after that (eight days after first dose) patient again experienced the lightning bolt pain two times on left side of head on left temple. States this was the same type of pain and her body jerked twice.  This is a spontaneous case concerning an 56year-old, female patient with a history of COVID-19 and Headaches, who experienced the unexpected serious events of Cerebrovascular accident and Anaphylactic reaction and unexpected non-serious events of Head discomfort, Pain, Dyskinesia and Headaches. The event Anaphylactic reaction occurred in two minutes after the first dose of mRNA-1273 vaccine. The event Cerebrovascular accident, Head discomfort, Pain and Dyskinesia occurred 5 days after the first dose of mRNA-1273 vaccine. The event Head discomfort (lightning bolt pain 2x on left side of head on left temple) occurred again 8 days after the first dose of mRNA-1273 vaccine. The Cerebrovascular accident (stroke) was not medically confirmed and to add that an MRIs were done, and the patient reported that it showed more damage after the vaccine (although site of MRI was not confirmed, and studies results were not available). Patient received Topamax as treatment for adverse event on an unknown date. The rechallenge was not applicable, as the events happened after the first dose. Patient reported that she has daily headaches that are on and off all day every day. Patients' medical history of Headaches can be confounder for the case. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning an 56year-old, female patient with a history of COVID-19 and Headaches, who experienced the unexpected serious events of Cerebrovascular accident and Anaphylactic reaction and unexpected non-serious events of Head discomfort, Pain, Dyskinesia and Headaches. The event Anaphylactic reaction occurred in two minutes after the first dose of mRNA-1273 vaccine. The event Cerebrovascular accident, Head discomfort, Pain and Dyskinesia occurred 5 days after the first dose of mRNA-1273 vaccine. The event Head discomfort (lightning bolt pain 2x on left side of head on left temple) occurred again 8 days after the first dose of mRNA-1273 vaccine. The Cerebrovascular accident (stroke) was not medically confirmed and to add that an MRIs were done, and the patient reported that it showed more damage after the vaccine (although site of MRI was not confirmed, and studies results were not available). Patient received Topamax as treatment for adverse event on an unknown date. The rechallenge was not applicable, as the events happened after the first dose. Patient reported that she has daily headaches that are on and off all day every day. Patients' medical history of Headaches can be confounder for the case. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.