Myocarditis; Pericarditis; my blood pressure was sky high/y blood pressure 166/139.; pulse was high/My pulse was 116; my heart was pounding bad; really sick with the shot; hurt so bad couldn't lift arm.; estrogen was low; arm got  hard/arm was rock hard; arm got very swollen/very swollen/arm was huge and  very swollen; arm was tender/arm hurt; fever; chills; like getting a cold; This spontaneous case was reported by a nurse and describes the occurrence of MYOCARDITIS (Myocarditis) and PERICARDITIS (Pericarditis) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 042J21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19.    On 31-Jan-2022, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Feb-2022, the patient experienced NASOPHARYNGITIS (like getting a cold), PYREXIA (fever) and CHILLS (chills). On an unknown date, the patient experienced MYOCARDITIS (Myocarditis) (seriousness criterion medically significant), PERICARDITIS (Pericarditis) (seriousness criterion medically significant), BLOOD PRESSURE INCREASED (my blood pressure was sky high/y blood pressure 166/139.), HEART RATE INCREASED (pulse was high/My pulse was 116), PALPITATIONS (my heart was pounding bad), VACCINATION COMPLICATION (really sick with the shot), VACCINATION SITE MOVEMENT IMPAIRMENT (hurt so bad couldn't lift arm.), BLOOD OESTROGEN DECREASED (estrogen was low), VACCINATION SITE INDURATION (arm got  hard/arm was rock hard), VACCINATION SITE SWELLING (arm got very swollen/very swollen/arm was huge and  very swollen) and VACCINATION SITE PAIN (arm was tender/arm hurt). The patient was treated with ASPIRIN [ACETYLSALICYLIC ACID] on 01-Feb-2022 at an unspecified dose and frequency; LORAZEPAM on 01-Feb-2022 for Anxiety, at an unspecified dose and frequency and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) on 01-Feb-2022 at an unspecified dose and frequency. At the time of the report, MYOCARDITIS (Myocarditis), PERICARDITIS (Pericarditis), BLOOD PRESSURE INCREASED (my blood pressure was sky high/y blood pressure 166/139.), HEART RATE INCREASED (pulse was high/My pulse was 116), PALPITATIONS (my heart was pounding bad), VACCINATION COMPLICATION (really sick with the shot), NASOPHARYNGITIS (like getting a cold), VACCINATION SITE MOVEMENT IMPAIRMENT (hurt so bad couldn't lift arm.), BLOOD OESTROGEN DECREASED (estrogen was low), VACCINATION SITE INDURATION (arm got  hard/arm was rock hard), VACCINATION SITE SWELLING (arm got very swollen/very swollen/arm was huge and  very swollen), PYREXIA (fever), CHILLS (chills) and VACCINATION SITE PAIN (arm was tender/arm hurt) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In August 2021, SARS-CoV-2 test: positive Positive. On an unknown date, Blood oestrogen: low (Low) Low. On an unknown date, Blood pressure measurement: around 90/58 aroung 90/58 and 166/139 it was 166/139. On an unknown date, Heart rate: 116 116.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Patient reported that it was almost time for second shot and stated that she was very concerned about, patient  woke up around 1 am her heart was pounding bad. Patient pulse was 116 and stayed like that for three hours scared. Patient stated that caller took treatment  and it calmed down and slowly started subsiding. Reporter stated that prescribed estrogen this past friday, Patient got myocarditis and pericarditis symptoms because her estrogen was low. Patient reported that wear heart monitor for 48 hours and awaiting results. Also having a stress test done this month. Patient took lorazepam during episode of high blood pressure and increased pulse. Reporter stated that it helped. Concomitant medication included: vitamins. CC: This case concerns a 52-year-old, female patient with past medical history of Covid-19 infection,  who experienced the expected serious AESI events of Myocarditis and Pericarditis. The event occurred on an unknown dates after the first dose of mRNA-1273 (Moderna covid-19 vaccine). The patient woke up in the morning with a pounding heart, pulse of 116. Patient was also reported to have low estrogen level and was prescribed estrogen for treatment. This patient's past history of Covid-19 infection and low estrogen level remains a confounder. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.     This case was linked to MOD-2022-499057 (Patient Link).; Sender's Comments: This case concerns a 52-year-old, female patient with past medical history of Covid-19 infection,  who experienced the expected serious AESI events of Myocarditis and Pericarditis. The event occurred on an unknown dates after the first dose of mRNA-1273 (Moderna covid-19 vaccine). The patient woke up in the morning with a pounding heart, pulse of 116. Patient was also reported to have low estrogen level and was prescribed estrogen for treatment. This patient's past history of Covid-19 infection and low estrogen level remains a confounder. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.