Kidney was starting to go down; to decline and now it was almost stage 4; This spontaneous case was reported by an other health care professional and describes the occurrence of RENAL IMPAIRMENT (Kidney was starting to go down; to decline and now it was almost stage 4) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Rheumatoid arthritis.   In January 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In March 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. In February 2021, the patient experienced RENAL IMPAIRMENT (Kidney was starting to go down; to decline and now it was almost stage 4) (seriousness criterion medically significant). At the time of the report, RENAL IMPAIRMENT (Kidney was starting to go down; to decline and now it was almost stage 4) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In February 2021, Liver function test: fine Fine. In February 2021, Renal function test: kidney was starting to go down; to decline and now (abnormal) Kidney was starting to go down; to decline and now it is almost stage 4..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No concomitant medication details were provided.   She had her blood checked on a regular basis. Her doctor asked her if she was taking any medication and she mentioned that she was on anti-hypertensive drug (unspecified). She could not think of anything new medication she took before having the kidney function test result except for the vaccine.  Company comment: This Spontaneous case concerns a female patient with age not reported, with medical history of Rheumatoid arthritis, experienced the unexpected serious AESI event Renal impairment, on an unknown date in the subsequent month after first dose of mRNA-1273. It was reported that the patient was on anti-hypertensive medication (not specified) and went for a routine blood test which revealed that the kidney function was going down to almost Stage4. At the time of reporting the event outcome was unknown. Patient's medical history of Rheumatoid arthritis and antihypertensive medication (and the condition itself) could be confounders. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This Spontaneous case concerns a female patient with age not reported, with medical history of Rheumatoid arthritis, experienced the unexpected serious AESI event Renal impairment, on an unknown date in the subsequent month after first dose of mRNA-1273. It was reported that the patient was on anti-hypertensive medication (not specified) and went for a routine blood test which revealed that the kidney function was going down to almost Stage4. At the time of reporting the event outcome was unknown. Patient's medical history of Rheumatoid arthritis and antihypertensive medication (and the condition itself) could be confounders. The benefit-risk relationship of mRNA-1273 is not affected by this report.