Asthma; Esophagitis; Gastritis; Muscle spasms; Heart palpitations; Heartburn; Felt symptoms ranging from shortness of breath; Chest pain; Some dizziness; Brain fog; oddly feel intense anxiety and depression; Some arm soreness at the injection site; A mild headache that began sometime around 8pm/eadache was quite intense; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of DYSPNOEA (Felt symptoms ranging from shortness of breath), CHEST PAIN (Chest pain), DIZZINESS (Some dizziness), FEELING ABNORMAL (Brain fog) and DEPRESSION (oddly feel intense anxiety and depression) in a 35-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 038A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Heartburn. Concomitant products included LANSOPRAZOLE (PREVACID) for Heartburn.    On 08-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 08-Apr-2021, the patient experienced DEPRESSION (oddly feel intense anxiety and depression), VACCINATION SITE PAIN (Some arm soreness at the injection site) and HEADACHE (A mild headache that began sometime around 8pm/eadache was quite intense). On an unknown date, the patient experienced DYSPNOEA (Felt symptoms ranging from shortness of breath), CHEST PAIN (Chest pain), DIZZINESS (Some dizziness), FEELING ABNORMAL (Brain fog), ASTHMA (Asthma), OESOPHAGITIS (Esophagitis), GASTRITIS (Gastritis), MUSCLE SPASMS (Muscle spasms), PALPITATIONS (Heart palpitations) and DYSPEPSIA (Heartburn). At the time of the report, DYSPNOEA (Felt symptoms ranging from shortness of breath), CHEST PAIN (Chest pain), DIZZINESS (Some dizziness), FEELING ABNORMAL (Brain fog), DEPRESSION (oddly feel intense anxiety and depression), ASTHMA (Asthma), OESOPHAGITIS (Esophagitis), GASTRITIS (Gastritis), MUSCLE SPASMS (Muscle spasms), PALPITATIONS (Heart palpitations), DYSPEPSIA (Heartburn), VACCINATION SITE PAIN (Some arm soreness at the injection site) and HEADACHE (A mild headache that began sometime around 8pm/eadache was quite intense) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: elevated (Inconclusive) Elevated slightly. On an unknown date, Cardiac stress test: unknown (Inconclusive) unknown. On an unknown date, Echocardiogram: unknown (Inconclusive) unknown. On an unknown date, Electrocardiogram: unknown (Inconclusive) unknown. On an unknown date, Endoscopy: showed moderate gastritis and esophagitis (Inconclusive) showed moderate gastritis and esophagitis. On an unknown date, Heart rate: elevated (Inconclusive) Elevated slightly. On an unknown date, Neutrophil count: 1.0 (Low) 1.0. On an unknown date, Vitamin D: 20 ng/mL (Low) 20ng/ml. On an unknown date, White blood cell count: 3.0 (Low) 3.0.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       Treatment medications were not provided.  Physical manifestation of anxiety and depression possibly induced by an inflammatory response from dose 1. Events described continued for roughly 2.5 to 3 weeks with the intensity highest around 3-7 days post vaccination, and slowly diminishing thereafter Patient states that he went to two different emergency room on 16APR2021 and 21APR2021.and was no admitted to ER   Most recent FOLLOW-UP information incorporated above includes: On 06-Jun-2021: Non-significant Follow up received on 06-JUN-2021, appended for AE contact Update