This is a spontaneous report from a contactable consumer (patient's mother). This mother reported for her 2 daughters. This is the 1st case (older daughter) out of the 2 cases. A currently 3-year-old female patient of an unspecified ethnicity received PREVNAR 13 (Lot # not available) via an unspecified route of administration at single on an unspecified date for immunization, following the CDC schedule for vaccination. The patient medical history included adenoidectomy. Concomitant medications were not reported. The patient previously took amoxicillin, amoxicillin sodium w/clavulanate potassium. The patient experienced recurrent infections on an unspecified date, getting more sick all the time on an unspecified date, cold on 04Aug2016, nasal discharge on an unspecified date, heavy growth strep/ heavy growth strep 2 infection on Nov2016, did not have immunity to any of the 13/ they were vaccinated but yet they are not having immunity on an unspecified date, sinus infection/ repeated continual sinus infection problems on an unspecified date, having persistent problems with illness on an unspecified date. The outcome of the events was unknown. Therapeutic measures were taken as a result of nasal discharge, heavy growth strep/ heavy growth strep 2 infection. Course of events: After the vaccinations, the child was fine but fast forward a year or so later she was having persistent problems with illness. In early August, the oldest daughter, six months after she received the last booster, she started having problems with recurrent infections. She would get a cold that would last and last for 3 plus weeks. The mother had really protected her in the beginning because she was a first time mom, but at this time period she was exposed to more germs than she ever had been. It was when she was 19 months that she started getting more sick all the time. She had a cold starting on 04Aug2016 that would not go away. She had a lot of nasal discharge that Amoxicillin would not take care of. ENT stopped the antibiotics she was on and put her on AUGMENTIN which was the strongest antibiotic they could prescribe for her. Heavy growth strep was diagnosed at the end of Nov2016 when she was 3 years and 1 month. Nasal swab test turned out that one of the child had Strep 2 and she needed to have her adenoids removed but she had a heavy growth Strep 2 infection so that we could not get rid of this antibiotics, it is extremely resistant to most all antibiotics. The  nasal swab result was a Strep in the category of 2 which was puzzling to the paediatrician because she had been vaccinated for the strains that are covered in that type 2 category. The Pneumo titers were done and has immunity has immunity to 1 out of the 13. [not reported clearly that out of the two children which child has immunity of 1 out of 13 and which child has immunity of 4 out of 2]. So the mother did not know if it was the 13 or if there was some that were outside of that has been vaccinated, she did not know but next one will be 4th. She was prescribed AUGMENTIN when her adenoids were removed (21Dec2016) for a 7 day course and within 7 days of the surgery she had green gunk coming out of her nose. She was right back to the place she had been. There was improvement for her and her younger sister for a few days while she was taking an antibiotic and then they had infections again. A pneumonia titer was done 22Dec2016 and it came back that she did not have immunity to any of the 13; she only had immunity to 19F. For the rest of the serotypes, the immunity was all under 2. Nasal Swab Test (Date unspecified): Strep type 2 infection. The family actually had different paediatrician during that time because they moved from one state to another but they were right on time with vaccinations, like within a day of the next eligible time period and the mother was calling about PREVNAR 13. The mother called since she was not sure but the children were vaccinated but then they found that they are having some repeated continual sinus infection problems. Her younger sibling has persistent sinus infections and there is the same situation with the younger sibling as with the oldest daughter. The mother concern was the fact the child was vaccinated but yet she was not having immunity towards she was vaccinated for and as a result have become quite ill. There is  a very resistant form of Strep and so the mother was wondering what was the percentage of efficacy when you go through the CDC recommended schedule of the 2 month, 4 month, 6 month and then between 12 and 15 month schedule. A Product Complaint was filed.