warm spot; sore spot; itchy spot; looked like a rash; shortness of breath, felt she could not breathe; tight chest; left and right arms felt cold like no circulation; her legs were weak; D-dimer was slightly elevated; wrist down through my forearm begun to feel tight, felt tension like a rubber band was on my arm; her right hand and it look like she had broken a vein in the palm of her hand, a bulge developed about the size of a sewing pin head; it stung; This spontaneous case was reported by a consumer and describes the occurrence of PERIPHERAL SWELLING (her right hand and it look like she had broken a vein in the palm of her hand, a bulge developed about the size of a sewing pin head), PARAESTHESIA (it stung), MUSCULOSKELETAL STIFFNESS (wrist down through my forearm begun to feel tight, felt tension like a rubber band was on my arm), DYSPNOEA (shortness of breath, felt she could not breathe) and CHEST DISCOMFORT (tight chest) in a 57-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 061E21A and 011D21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 20-Sep-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 18-Oct-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 21-Oct-2021, the patient experienced PERIPHERAL SWELLING (her right hand and it look like she had broken a vein in the palm of her hand, a bulge developed about the size of a sewing pin head) and PARAESTHESIA (it stung). On 01-Nov-2021, the patient experienced MUSCULOSKELETAL STIFFNESS (wrist down through my forearm begun to feel tight, felt tension like a rubber band was on my arm). On 02-Nov-2021, the patient experienced DYSPNOEA (shortness of breath, felt she could not breathe), CHEST DISCOMFORT (tight chest), PERIPHERAL COLDNESS (left and right arms felt cold like no circulation), MUSCULAR WEAKNESS (her legs were weak) and FIBRIN D DIMER INCREASED (D-dimer was slightly elevated). On an unknown date, the patient experienced VACCINATION SITE WARMTH (warm spot), VACCINATION SITE PAIN (sore spot), VACCINATION SITE PRURITUS (itchy spot) and VACCINATION SITE RASH (looked like a rash). The patient was treated with IBUPROFEN for Adverse event, at a dose of 800 mg; CEFADROXIL (BID) for Adverse event, at an unspecified dose and frequency and VITAMIN E [VITAMIN E NOS] for Adverse event, at an unspecified dose and frequency. At the time of the report, PERIPHERAL SWELLING (her right hand and it look like she had broken a vein in the palm of her hand, a bulge developed about the size of a sewing pin head), PARAESTHESIA (it stung), MUSCULOSKELETAL STIFFNESS (wrist down through my forearm begun to feel tight, felt tension like a rubber band was on my arm), DYSPNOEA (shortness of breath, felt she could not breathe), CHEST DISCOMFORT (tight chest), PERIPHERAL COLDNESS (left and right arms felt cold like no circulation), MUSCULAR WEAKNESS (her legs were weak), FIBRIN D DIMER INCREASED (D-dimer was slightly elevated), VACCINATION SITE WARMTH (warm spot), VACCINATION SITE PAIN (sore spot), VACCINATION SITE PRURITUS (itchy spot) and VACCINATION SITE RASH (looked like a rash) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Computerised tomogram: normal (normal) Normal No clots. On an unknown date, Fibrin D dimer: elevated (High) elevated. On an unknown date, X-ray: normal (normal) normal No clots.         The Patient stated that scans of her Heart were fine.  No Concomitant Medications were provided by the reporter   This case was linked to MOD-2021-372402 (Patient Link).