hypothyroidism; tremors; heart rate was at 133; very bad anxiety; lost 12 pounds in 12 week; hair loss; unable to do her daily things; thyroiditis/TSH level was 0. 1; fear; palpitations; pain in joints; pain in neck; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 40 year-old female patient received bnt162b2 (BNT162B2), administration date 23May2021 (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. Relevant medical history included: "anemic" (unspecified if ongoing), notes: took iron pills. The patient took concomitant medications. Vaccination history included: Bnt162b2 (Dose 1), administration date: 2021, for COVID-19 Immunization. The following information was reported: HYPOTHYROIDISM (medically significant), outcome "unknown", described as "hypothyroidism"; ANXIETY (non-serious) with onset Jul2021, outcome "recovering", described as "very bad anxiety"; NECK PAIN (non-serious) with onset 2021, outcome "recovered", described as "pain in neck"; THYROIDITIS (non-serious) with onset Jul2021, outcome "unknown", described as "thyroiditis/TSH level was 0. 1"; FEAR (non-serious) with onset Jul2021, outcome "recovering", described as "fear"; PALPITATIONS (non-serious) with onset Jul2021, outcome "recovered", described as "palpitations"; ARTHRALGIA (non-serious) with onset 2021, outcome "recovering", described as "pain in joints"; WEIGHT DECREASED (non-serious) with onset Jul2021, outcome "unknown", described as "lost 12 pounds in 12 week"; ALOPECIA (non-serious) with onset Jul2021, outcome "unknown", described as "hair loss"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious) with onset Jul2021, outcome "unknown", described as "unable to do her daily things"; TREMOR (non-serious), outcome "unknown", described as "tremors"; HEART RATE INCREASED (non-serious), outcome "recovering", described as "heart rate was at 133". The events "hypothyroidism", "very bad anxiety", "pain in neck", "thyroiditis/tsh level was 0. 1", "fear", "palpitations", "pain in joints", "lost 12 pounds in 12 week", "hair loss", "unable to do her daily things", "tremors" and "heart rate was at 133" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: blood thyroid stimulating hormone: (Jul2021) 0.1, notes: diagnosed with thyroiditis; heart rate: (unspecified date) 133; (unspecified date) 60; weight: (unspecified date) lost 12 pounds in 12 week; (unspecified date) loss, notes: loss weight in 2 weeks. Clinical course: The patient received 1st and 2nd shots of the vaccine last year. Her 2nd dose was on 23May2021 and after that she had pain in neck for 2 -3 weeks. The patient did not go to the doctor, she thought she would be good after some time. The patient had palpitation 3 - 4 weeks later, massive amount of them, very bad anxiety, and fear, pain in joints, she went to Dr around Aug, very late. She was diagnosed with thyroiditis her doctor was not sure if it was because of the vaccine or not. She did not go to the doctor because she was able to perform her functions. None of her family had problems related to thyroid. She wanted to know if there were more reports of thyroiditis or thyrotoxicosis after getting the vaccine. She was planning taking the booster, but she lost 12 pounds in 12 weeks, no able to perform to due to this condition. In Jul2021 the patient started to have lots of palpitations and lost weight. Her symptoms got worse. Her TSH level was 0. 1 was diagnosed with thyroiditis. She had a lot of anxiety and fear. She had weight loss, hair loss. She was unable to do her daily things. Now she was getting close to getting normal. It took 6-7 months to get to normal. Her doctor didn't have the answer to this as well. The patient stated she wasn't fully better; she may take a lifelong medication. After the 2nd dose on 23May2021, she experienced pain around the neck. 3 - 4 weeks later palpitations, massive amount of them. Her heart rate was at 133. She experienced tremors, fear, and anxiety. She also lost weight in 2 weeks. She was diagnosed with thyroiditis; all her symptoms were of hypothyroidism. Now her palpitations were gone, and her heart rate was at 60. She was in control with an endocrinologist.   No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.