Rash; Leg pain; Very tired; Late saturday after noon the back of my head became itchy and then itchy behind my ears; This is a spontaneous report received from contactable reporter(s) (Other HCP). The reporter is the patient.  A 52-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 20May2022 at 16:00 as dose 3 (booster), single (Lot number: FM9992) at the age of 52 years, in left arm for covid-19 immunization. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE: 2, product=COVID 19, brand=Pfizer, lot unknown reason other=Don't have it on me at this time, vaccine location=Left arm), administration date: 15Apr2021, when the patient was 51-year-old, for COVID-19 Immunization, reaction(s): "leg pain"; BNT162b2 (DOSE: 2), administration date: 15Apr2021, when the patient was 51-year-old, for Covid-19 Immunization, reaction(s): "Very tired"; BNT162b2 (DOSE: 1, product=COVID 19, brand=Pfizer, prev dose lot unknown reason other=don't have card on me at this time,, administration time=10:00AM, vaccine location=Left arm), administration date: 09Mar2021, when the patient was 51-year-old, for Covid-19 Immunization. The following information was reported: PRURITUS (non-serious) with onset 21May2022 at 16:00, outcome "not recovered", described as "Late Saturday after noon the back of my head became itchy and then itchy behind my ears"; PAIN IN EXTREMITY (non-serious) with onset 21May2022 at 16:00, outcome "not recovered", described as "Leg pain"; RASH (non-serious) with onset 21May2022 at 16:00, outcome "not recovered"; FATIGUE (non-serious) with onset 21May2022 at 16:00, outcome "not recovered", described as "Very tired". The events "rash", "leg pain", "very tired" and "late Saturday after noon the back of my head became itchy and then itchy behind my ears" required physician office visit. Therapeutic measures were taken as a result of rash, pain in extremity, fatigue, pruritus. Additional information: Patient Age group reported as Adult (18-64 Years). Facility type vaccine was Pharmacy or Drug Store. There was no other vaccine in four weeks and no other medications in two weeks. The patient received the first booster on 20May at 4pm at her local drug store. She was fine until 3am, she woke up with leg pain and very tired.  Went back to sleep throughout Saturday she slept most of the day. Same reaction with second vaccine. Late Saturday after noon the back of her head became itchy and then itchy behind her ears. She took an antihistamine and put cream on. Sunday same thing happened. Monday at 4 am work up to a rash and itchy areas to her neck n chest. It was driving her crazy. She took another antihistamine and added more cream like she did on Saturday and Sunday. Monday called Dr. was seen at 3:30 pm yes allergic reaction. Never in her life have she had an allergic reaction and or rash. Dr. put her on steriod, Pepcid for her stomach because of steriods, Benedryl and cream. Had to see an allergist earliest appointment was Jul12. Again never a reaction to anything in her life. She had pictures from Monday morning. Sender's Comments: Linked Report(s) : US-PFIZER INC-202200754779 similar report from same reporter.