awful; Caller stated "things were going on, on the back of her leg" and she could "feel heat on her leg."; face was swollen as well as her tongue, mouth, and lip; face was swollen as well as her tongue, mouth, and lip; face was swollen as well as her tongue, mouth, and lip; face was swollen as well as her tongue, mouth, and lip; on the third day after administration, her right hand was swollen; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 65 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 19Mar2021 16:30 (Lot number: EN6204, Expiration Date: 30Jun2021) at the age of 65 years as dose 1, 0.3 ml single for covid-19 immunisation. Relevant medical history included: "obese" (unspecified if ongoing), notes: Patient History: No; "handicapped" (unspecified if ongoing). There were no concomitant medications. The following information was reported: MOUTH SWELLING (non-serious), LIP SWELLING (non-serious), SWOLLEN TONGUE (non-serious), SWELLING FACE (non-serious) all with onset 23Mar2021, outcome "recovered" (2021) and all described as "face was swollen as well as her tongue, mouth, and lip"; PERIPHERAL SWELLING (non-serious) with onset 23Mar2021, outcome "recovered" (2021), described as "on the third day after administration, her right hand was swollen"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "awful"; FEELING HOT (non-serious), outcome "unknown", described as "Caller stated "things were going on, on the back of her leg" and she could "feel heat on her leg."". The events "face was swollen as well as her tongue, mouth, and lip", "face was swollen as well as her tongue, mouth, and lip", "face was swollen as well as her tongue, mouth, and lip", "face was swollen as well as her tongue, mouth, and lip", "on the third day after administration, her right hand was swollen", "awful" and "caller stated "things were going on, on the back of her leg" and she could "feel heat on her leg."" were evaluated at the physician office visit and emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of mouth swelling, lip swelling, swollen tongue, swelling face, peripheral swelling.  Additional information: Reporter on the line who states she was 65 at the time of the vaccine but she is now 66, states she received her first dose of Pfizer Covid vaccine one day around 4:30 PM, states on the third day she woke with swelling in her right leg and her right hand, states her right leg was twice the normal size, states she was unable to move her leg or get it off the bed, states the swelling progressed up into her face, tongue, mouth, and lips on the fourth day. Reporter states things were going on the back of her leg, like she felt heat on the back of her leg and it was so big and swollen, on the fourth day she went to the ER and they took blood and checked for blood clots and they did not find any blood clots, states that she is handicapped which was prior to the vaccine, states consulted with her doctor that she does not like, states she ten saw her pulmonologist yesterday and told her not to get second dose of Pfizer but instructed her to get the Moderna. Reporter is asking if she was to receive the second dose or booster dose of the Pfizer covid-19 vaccine, would it hurt her or protect her.   No follow-up attempts are possible. No further information is expected.