Mast Cell Activation Syndrome; Suffered bishopric anaphylactic reactions; no quality of life, who can live in a secluded bubble; barely being able to eat; This spontaneous case was reported by a patient and describes the occurrence of MAST CELL ACTIVATION SYNDROME (Mast Cell Activation Syndrome) and ANAPHYLACTIC REACTION (Suffered bishopric anaphylactic reactions) in a  patient of an unknown age and gender who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Allergy (Patient confirmed allergy to the antibody NOT the excipients. No one will treat patient with the appropriately modalities.).    In May 2021, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced MAST CELL ACTIVATION SYNDROME (Mast Cell Activation Syndrome) (seriousness criterion medically significant), ANAPHYLACTIC REACTION (Suffered bishopric anaphylactic reactions) (seriousness criterion medically significant), IMPAIRED QUALITY OF LIFE (no quality of life, who can live in a secluded bubble) and FEEDING DISORDER (barely being able to eat). At the time of the report, MAST CELL ACTIVATION SYNDROME (Mast Cell Activation Syndrome), ANAPHYLACTIC REACTION (Suffered bishopric anaphylactic reactions), IMPAIRED QUALITY OF LIFE (no quality of life, who can live in a secluded bubble) and FEEDING DISORDER (barely being able to eat) had not resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       Concomitant product use was not provided by the reporter.  Patient received Moderna vaccine in May-2021, subsequently suffered bishopric anaphylactic reactions and had been diagnosed with Mast Cell Activation Syndrome.  Patient reported no quality of life and had not seen children, partner, family, work, home since 9 months because of this. Patient had to quit school because of this. Patient can no longer continue with career.  Patient wanted help to get the appropriate treatment. Patient stated that antibody needs to come out of patient's body, otherwise all of the Epi injections patient had been using on a daily basis will kill the patient. Patient was barely being able to eat and had been taking 15 medications and an equal number of supplements that do not exactly help to the patient.  Patient was truly alive before all this and used to be passionate about their career.   patient reported treatment medication as Epi injections, 15 other medications and an equal number of supplements.  Company comment: This spontaneous case concerns a patient with unspecified age and gender, with Concurrent medical conditions of Allergy (Patient confirmed allergy to the antibody NOT the excipients), who experienced unexpected serious event of Mast cell activation syndrome and Anaphylactic reaction (seriousness criteria medically significant) which occurred on unspecified day after a dose of mRNA-1273 vaccine (dose number not specified). It was reported that treatment medication of Epi injections ,15 other medications with supplements were prescribed. Patient's Concurrent medical conditions of Allergy remain the confounder for the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report; Sender's Comments: This spontaneous case concerns a patient with unspecified age and gender, with Concurrent medical conditions of Allergy (Patient confirmed allergy to the antibody NOT the excipients), who experienced unexpected serious event of Mast cell activation syndrome and Anaphylactic reaction (seriousness criteria medically significant) which occurred on unspecified day after a dose of mRNA-1273 vaccine (dose number not specified). It was reported that treatment medication of Epi injections ,15 other medications with supplements were prescribed. Patient's Concurrent medical conditions of Allergy remain the confounder for the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report