Diagnosed with COVID-19 "6 weeks ago"; Diagnosed with angina; This spontaneous case was reported by a consumer and describes the occurrence of ANGINA PECTORIS (Diagnosed with angina) in a 69-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 009C21A and 044A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Stent insertion NOS (Doing great after receiving stent) on 14-Feb-2020. Concurrent medical conditions included Blood pressure high, Angina pectoris and Heart disease, unspecified.   On 23-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 milliliter. On 24-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. In May 2021, the patient experienced ANGINA PECTORIS (Diagnosed with angina) (seriousness criterion medically significant). On an unknown date, the patient experienced COVID-19 (Diagnosed with COVID-19 "6 weeks ago"). The patient was treated with NITROGLYCERIN for Angina pectoris, at an unspecified dose and frequency. At the time of the report, ANGINA PECTORIS (Diagnosed with angina) was resolving and COVID-19 (Diagnosed with COVID-19 "6 weeks ago") outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In May 2021, Cardiac stress test: abnormal (abnormal) Abnormal - Diagnosed with angina.. On an unknown date, SARS-CoV-2 test: positive (Positive) Positive.     mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date.       No concomitant medication provided.  Patient completed primary COVID-19 series in 2021, however, a week after the second dose, got a stress test and a week from that was diagnosed with angina. Hurt so bad went to the ER and got treatment. Wonders if his heart became inflamed or swollen after receiving the second dose. The next 4 months, felt like they were going to die cause of angina. Would get out of breath when walking.  After a year, reported the angina started to go away and was almost gone. Still doesn't feel as good as they did before shots, was upset about this.  Has had other vaccines but never a reaction like this. Was told to take the booster but has refused.  Company comment: This spontaneous case concerns a 69-year-old, male patient with relevant medical history of blood pressure high, angina pectoris and heart disease, who experienced serious (Medically significant) unexpected event of Angina pectoris and non-serious unexpected AESI event of COVID 19 unspecified days after receiving second dose of mRNA-1273 Vaccine. Patient reported that he was out of breath while walking and it was hurting so bad that he went to the ER and got treatment. Patient also wonders if his heart became inflamed or swollen after receiving the second dose and felt like he was going to die cause of angina. After a year, the angina started to go away and was almost gone but he still doesn't feel as good as they did before shots. Cardiac stress test of the patient revealed angina. Current pandemic situation of COVID 19 could be risk factor for the event COVID 19. Treatment of the patient included Nitroglycerine. Medical history of blood pressure high, angina pectoris and heart disease could be confounders for the event Angina pectoris. At the time of the report, Angina pectoris was resolving and outcome of the event COVID 19 was unknown. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-491919 (Patient Link).; Sender's Comments: This spontaneous case concerns a 69-year-old, male patient with relevant medical history of blood pressure high, angina pectoris and heart disease, who experienced serious (Medically significant) unexpected event of Angina pectoris and non-serious unexpected AESI event of COVID 19 unspecified days after receiving second dose of mRNA-1273 Vaccine. Patient reported that he was out of breath while walking and it was hurting so bad that he went to the ER and got treatment. Patient also wonders if his heart became inflamed or swollen after receiving the second dose and felt like he was going to die cause of angina. After a year, the angina started to go away and was almost gone but he still doesn't feel as good as they did before shots. Cardiac stress test of the patient revealed angina. Current pandemic situation of COVID 19 could be risk factor for the event COVID 19. Treatment of the patient included Nitroglycerine. Medical history of blood pressure high, angina pectoris and heart disease could be confounders for the event Angina pectoris. At the time of the report, Angina pectoris was resolving and outcome of the event COVID 19 was unknown. The benefit-risk relationship of mRNA-1273 is not affected by this report.