GERD and acid reflux has disappeared after her COVID-19 vaccines; She was having some stomach discomfort; she has the pushing and pressing on her chest; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 76-year-old female patient received BNT162b2 (BNT162B2), on 01Jun2022 as dose 4 (booster), single (Lot number: FM7553) at the age of 76 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Asthma" (unspecified if ongoing), notes: She has had asthma for probably 10 years.; "acid reflux" (unspecified if ongoing); "GERD" (unspecified if ongoing). Concomitant medication(s) included: PANTOPRAZOLE taken for gastroesophageal reflux disease; TUMS [CALCIUM CARBONATE] taken for gastroesophageal reflux disease; ROLAIDS [CALCIUM CARBONATE;MAGNESIUM HYDROXIDE] taken for gastroesophageal reflux disease; NEXIUM [ESOMEPRAZOLE MAGNESIUM] taken for gastroesophageal reflux disease. Vaccination history included: BNT162b2 (Dose 1, Single, Lot Number: EN6198, route of administration; Left upper arm), administration date: 25Feb2021, when the patient was 74-year-old, for COVID-19 Immunization, reaction(s): "GERD and acid reflux has disappeared after her COVID-19 vaccines"; BNT162b2 (Dose 2, Single, Lot Number: EN6206 or EN6266, Route, Anatomical Location: Left upper arm), administration date: 18Mar2021, when the patient was 74-year-old, for COVID-19 Immunization, reaction(s): "GERD and acid reflux has disappeared after her COVID-19 vaccines"; BNT162b2 (Dose 3, Single, Lot Number: FF8841, Route, Anatomical Location: Left upper arm), administration date: 09Nov2021, when the patient was 75-year-old, for COVID-19 Immunization, reaction(s): "GERD and acid reflux has disappeared after her COVID-19 vaccines". The following information was reported: THERAPEUTIC RESPONSE UNEXPECTED (non-serious) with onset Jun2022, outcome "unknown", described as "GERD and acid reflux has disappeared after her COVID-19 vaccines"; ABDOMINAL DISCOMFORT (non-serious) with onset Jun2022, outcome "recovered" (Jun2022), described as "She was having some stomach discomfort"; CHEST DISCOMFORT (non-serious) with onset Jun2022, outcome "recovered" (Jun2022), described as "she has the pushing and pressing on her chest".  Additional information: Patient had GERD and acid reflux, and this disappeared 2 days after the first shot up to a couple days before her second shot and then 2 days after her second shot this went away. She reports the same thing happened after her booster shot as well where the GERD and acid reflux came back before her booster shot and then went away again after. The GERD and acid reflux went away after all 4 COVID-19 Vaccine. She states she has a good friend who has a good friend that works with Pfizer in the research department that recommended she tell her doctor to report this, and she decided to call herself. She thinks there was something in the product that resolves acid reflux problems. She was not sure if she was cured but her symptoms are gone. She states 2 days after her first 2 shots of the COVID-19 Vaccine her acid reflux was completely gone. She could have eaten battery acid, and this wouldn't have hurt her. 4 days after her first booster COVID-19 vaccine, the acid reflux and GERD was gone and then 5 days after her 2nd booster dose of the COVID-19 Vaccine that she received last week she has no acid reflux and was gone. She had her last COVID-19 Vaccine booster dose a week ago Tuesday and feels fine. Time the Vaccination Was Given: 01Jun2022 before noon between 11am and 12pm. She doesn't know how long this will last but states she has such a marked improvement and can breathe. She was having some stomach discomfort and as the acid was pushing up in her esophagus. She states some people have burping but she has the pushing and pressing on her chest. She also has asthma which enhances her discomfort, but all of this was completely gone. There was no prior vaccinations within four weeks. There were no relevant tests. She was happy to do the report if this could help people and if this could eventually find a medication that helps with acid reflux. She asks what was in the vaccine that does calm one's stomach from the acid production. If this could help isolate what was in the vaccine, she would be happy to know. She states she imagines if Pfizer could find a pill that actually works then she like others wouldn't have to watch what she eats. She states this would be nice if Pfizer could eradicate acid reflux.