Got the modema covid vaccine and developed a rash in several areas of her body, but the MD did biopsy and said it was eczema; Diarrhea; Experiencing droopy left eye that bounces back to normal; Muscle twist on left eye; This spontaneous case was reported by a patient and describes the occurrence of ECZEMA (Got the modema covid vaccine and developed a rash in several areas of her body, but the MD did biopsy and said it was eczema), DIARRHOEA (Diarrhea), EYELID PTOSIS (Experiencing droopy left eye that bounces back to normal) and MUSCLE STRAIN (Muscle twist on left eye) in an 81-year-old female patient who received mRNA-1273 (Spikevax) for COVID-19 vaccination.    Co-suspect product included non-company product DUPILUMAB (DUPIXENT) for Dermatitis atopic and Psoriasis vulgaris.    No Medical History information was reported.   In October 2022, the patient received dose of mRNA-1273 (Spikevax) (unknown route) 1 dosage form. In April 2023, the patient started DUPILUMAB (DUPIXENT) (Subcutaneous) 300 milligram once a week. In April 2023, the patient experienced ECZEMA (Got the modema covid vaccine and developed a rash in several areas of her body, but the MD did biopsy and said it was eczema), DIARRHOEA (Diarrhea), EYELID PTOSIS (Experiencing droopy left eye that bounces back to normal) and MUSCLE STRAIN (Muscle twist on left eye). The patient was treated with LOPERAMIDE HYDROCHLORIDE (IMODIUM A-D) for Diarrhoea, at an unspecified dose and frequency; ELECTROLYTES NOS, GLUCOSE (PEDIALYTE [ELECTROLYTES NOS;GLUCOSE]) for Diarrhoea, at an unspecified dose and frequency and BISMUTH SUBSALICYLATE (PEPTO-BISMOL) for Diarrhoea, at an unspecified dose and frequency. At the time of the report, ECZEMA (Got the modema covid vaccine and developed a rash in several areas of her body, but the MD did biopsy and said it was eczema) had not resolved and DIARRHOEA (Diarrhea), EYELID PTOSIS (Experiencing droopy left eye that bounces back to normal) and MUSCLE STRAIN (Muscle twist on left eye) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Biopsy: Eczema.     The action taken with mRNA-1273 (Spikevax) (Unknown) was unknown.   For mRNA-1273 (Spikevax) (Unknown), the reporter did not provide any causality assessments.   Concomitant product use was not provided by the reporter.  At the time of the event, the patient had ongoing Eczema and Itching.   In Apr-2023, the patient developed a non-serious event.  The patient reported experiencing droopy left eye that bounced back to normal. MD was aware and informed patient to monitor. Patient stated dupixent improved her eczema and itchiness in the beginning but was not helping as much anymore.   The patient got the Modera COVID vaccine around 01-Oct-2022 and developed a rash in several areas of her body that never really went away, but the MD did biopsy and said it was eczema. Advised patient on using Imodium a-d otc or generic loperamide irn and to replenish her fluid, recommended Pedialyte.   The patient had muscle twist on left eye, but confirmed it was not conjunctivitis, no eye inflammation nor pink eye. Advised patient to notify MD about diarrhea. Counseled patient on side effects and if she had any eye problems like irritation, swelling or severe itching since dupixent can cause conjunctivitis or keratitis.   Action taken with respect to Dupixent: No action taken for diarrhoea, muscle strain and unknown for other events.