fire in my arm; High blood pressure; body feel hot; hair has fallen out at an alarming rate; hot flashes; severe heartburn; allergic to your vaccine; Throat swelled closed; Throat swelled closed; The initial case was missing the following minimum criteria: ICH- Unspecified product. Upon receipt of follow-up information on (16Aug2022), this case now contains all required information. This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID. The reporter is the patient. A 55-year-old female patient received BNT162b2 (BNT162B2), on 28Oct2021 as dose 1, single (Lot number: 320308D) at the age of 55 years for covid-19 immunisation. The patient's relevant medical history included: "post menopausal" (unspecified if ongoing), notes: had been hot flash free for 2 years. The patient took concomitant medications included Vitamins. The following information was reported: PHARYNGEAL SWELLING (medically significant), THROAT TIGHTNESS (medically significant) all with onset 28Oct2021, outcome "not recovered" and all described as "Throat swelled closed"; ALLERGY TO VACCINE (medically significant) with onset 28Oct2021, outcome "not recovered", described as "allergic to your vaccine"; DYSPEPSIA (non-serious) with onset 04Nov2021, outcome "not recovered", described as "severe heartburn"; HOT FLUSH (non-serious) with onset 11Jan2022, outcome "not recovered", described as "hot flashes"; ALOPECIA (non-serious) with onset 21Mar2022, outcome "not recovered", described as "hair has fallen out at an alarming rate"; BURNING SENSATION (non-serious), outcome "unknown", described as "fire in my arm"; HYPERTENSION (non-serious), outcome "recovering", described as "High blood pressure"; FEELING HOT (non-serious), outcome "unknown", described as "body feel hot". The patient underwent the following laboratory tests and procedures: Blood pressure measurement: High. Therapeutic measures were taken as a result of allergy to vaccine included Benadryl, pharyngeal swelling, throat tightness, dyspepsia, hot flush, alopecia. Clinical course reported as: consumer stated she was allergic to the vaccine. Throat swelled closed. Therefore she could not get a second dose. The first vaccine also gave her severe heartburn within couple of weeks. She had never had it before. She was struggling with it. She was post menopausal and had been hot flash free for 2 years. The hot flashes also returned after the vaccine. Her hair has fallen out at an alarming rate which she hadn't had this bad in the past. She could not take PPI's- Now she was allergic to those. Where she had never had allergic reactions to med before. She did not go to the hospital. Treated on site. The right side of her throat now swells some or feels now if I had other seasonal allergies. She had never had any health issues in the past. Since she had first COVID vaccine, she had a lot more issues with her health. Her throat would bother her on right with foods and drink. High blood pressure showed up but it was going back to normal. If her mouth got dry more it was the right-side 1st heartburn bothered her severely. Now she could not take PPIs for undecipherable, it brothered and made her throat and tongue swell store. She had limited what she could eat, When she received the Pfizer vaccine. It was like fire in her arm and her throat started swelling instantly. The shot made her whole body feel hot. Allergist said she had an allergic reaction to vaccine and does not recommend her get another one.