This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient. A 77-year-old female patient received BNT162b2 (BNT162B2), on 20Dec2021 as dose 3 (booster), single (Lot number: FH8028) at the age of 77 years for covid-19 immunisation. The patient's relevant medical history included: "Restless legs syndrome" (unspecified if ongoing); "Neuropathy in the feet" (unspecified if ongoing), notes: Neuropathy in the feet; "Drug allergy" (unspecified if ongoing), notes: She is allergic to Penicillin and any other Penicillin derivatives, Zolair, and gabapentin; "Shellfish allergy" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: BNT162b2 (Dose 1, Single, Lot EN5318), administration date: 14Apr2021, when the patient was 76-year-old, for COVID-19 Immunization; BNT162b2 (Dose 2, Single, She does not know the first character of the Lot number as it is covered by a sticker, but after that it is R8736.), administration date: 05May2021, when the patient was 76-year-old, for COVID-19 Immunization, reaction(s): "Itchiness in head/body", "big spots on her head, big spots and rash on her stomach", "welts", "hard knot on scalp". The following information was reported: ALLERGY TO VACCINE (non-serious) with onset 2021, outcome "not recovered", described as "Itching scalp and body/Hard knot and spots on scalp". The events "itching scalp and body/hard knot and spots on scalp" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of allergy to vaccine. Additional Information: She was calling about the Pfizer covid vaccine, it's her head, she has called about this earlier, she has 4 spots on it, and hard knots in it. She has gotten it tested, they did a biopsy on them, and it was discovered that it was an allergic reaction. She was allergic to propylene glycol, it was getting better, she was using special shampoo without propylene glycol, and she was still continuing the shampoo. She was not using laundry soap, but she went on a vacations and was in a hotel and used their soaps and so therefore she has spots and hard knots still. The doctor said that it's got into her hair follicles. The doctors felt the vaccine has caused a chemical imbalance in the system, which is showing up in the head, which it initially started with her being so itchy, it is not as itchy now, but she has had itching since 2021. She has had the first, second, and booster shot and there will not be another one. At first caller stated, that the spots, hard knots, and terrible itching started in 2021, she recalls waking up with itching in the middle of the night. Caller later states that she is not sure if it was specifically 2021 and may have started some time before that, it's just that she connected it all in 2021. She has gone through allergy tests and has seen an allergist. She has all the paperwork with results. She clarified that the itching was not only on the scalp, it was on right butt cheek, it cleared up now, and it was also across the stomach. Those 2 spots have cleared up, but on the head it's back again.  Caller states not to put it started in Aug2021, she clarified that is when she remembers it, but it started sooner than that, August is just when she remembers or noticed. She asked to write events started sometime in 2021. The itching scalp was getting better but after the vacation not quite, it worse. Itching on body, it's been about a month since it's gone away, at first when it started the skin looks like it was dry, that's what it looked like, if she touched, it would welt right up, at the moment it looks normal both her stomach and butt cheek. She clarified it is not just one hard knot, it is throughout the scalp, it's worse since she went on vacation, she was gone for 3 weeks. She believes it was the laundry soap from hotels. Caller described the spots as being red with white on the tip, the spots are about the size of her diamond which is shy of half a karat, it's the size of her diamond, these spots are also dispersed throughout the scalp. The anatomical location of where the shots were administered on her body were unknown. She has had an issue with a vaccine in the past, it was called Zolair, she was administered this about 2-3 years ago, she has no Lot or expiry of Zolair (as reported). She went to a dermatologist and allergist. She has had an allergy test for chemicals, they did a skin prick test, the only thing that triggered on the test was propylene glycol, the doctor was shocked saying that nobody is usually allergic to that. She did this test just within the last couple of months. She has a specific shampoo she uses for which she went online, she made sure that it did not have Propylene Glycol, it is an over-the-counter Shampoo without Propylene Glycol called T/Gel made by Neutrogena. The dermatologist gave her a cream, a moose and an oil, she was then sent to an allergist, and the allergist told her that she was going to flare up in a couple weeks because the product the dermatologist gave her had Propylene Glycol. The products from the dermatologist, she went back to flaring, it did nothing, they had Propylene Glycol in it, so she threw it all away. The allergist prescribed nothing, the allergist said he was at a loss and cannot help her. Sender's Comments: Linked Report(s) : PFIZER INC-202200473812 Same patient/drug, different dose/event;