her whole face was swelling/ looked like she was paralyzed/left side of her face and cheek and nose was swollen; lips were all swollen; scared to death; blood pressure can get a little high; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 73-year-old female patient received BNT162b2 (BNT162B2), on 28Jun2022 as dose 4 (booster), single (Lot number: FM0173) at the age of 73 years, in left arm for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: BNT162b2 (DOSE 1, Lot: EN6202, Expiry: Jun2021, site of administration: Left arm at 10:00), administration date: 04Mar2021, when the patient was 72-year-old, for Covid-19 immunization; BNT162b2 (DOSE 3, Lot: FC3183), administration date: 07Oct2021, when the patient was 73-year-old, for Covid-19 immunization; Bnt162b2 (DOSE 2 , Lot: EP6955), administration date: Mar2021, when the patient was 72 years old, for Covid-19 immunization.The following information was reported: BLOOD PRESSURE INCREASED (non-serious) with onset Jun2022, outcome "unknown", described as "blood pressure can get a little high"; FEELING OF DESPAIR (non-serious) with onset Jun2022, outcome "unknown", described as "scared to death"; SWELLING FACE (medically significant) with onset 29Jun2022, outcome "recovering", described as "her whole face was swelling/ looked like she was paralysed/left side of her face and cheek and nose was swollen"; LIP SWELLING (medically significant) with onset 29Jun2022, outcome "recovering", described as "lips were all swollen". The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (Jun2022) blood pressure can get a little high, notes: blood pressure can get a little high so she takes the lowest dose of Lisinopril when it gets a little high which is 1 pill a day. Therapeutic measures were taken as a result of swelling face, lip swelling, blood pressure increased.  Clinical Course: The patient woke up at 06:00 on 29Jun2022, and because her mouth was feeling swollen, she looked in the mirror and her lips were all swollen, up the left side of her face and cheek was swollen and looked like a big baseball. She did everything she could and got a washcloth and put ice on it. She kept that on most of the day. She did not feel bad, it was just all the swelling which seemed like it started going more toward her eyes on both sides and her whole face was swelling. She spoke to a pharmacist who suggested she see a doctor. She saw a Nurse Practitioner on 29Jun2022 at a clinic close to her house. She looked like a chimpanzee, even her nose was swollen by that time. While at the clinic she got a Dexamethasone steroid shot and today event is much better. She still has what looks like, on the left side, like she has a wad of chewing tobacco hanging down where her jawbone. It looked like she was paralysed. She has never had a reaction other than maybe a little bit of a sore arm before. After treatment or medical interventions, she was just given the Dexamethasone shot; and was given a prescription to take Prednisone. She had not even opened the Prednisone yet; she just picked it up today and was supposed to start Prednisone today; but she was not sure she was even to take the Prednisone because the only thing significant left was the lump on the left side of her cheek. If that was gone tomorrow, she may not take the Prednisone. She does not like to take drugs; she was an anti-drug person since having cared for her husband and mother for 12 years. She is going to try not to take the Prednisone; but if she sees that the swelling was starting to get worse then she will take it.  No follow-up attempts are possible. No further information is expected.