Joint pain that got progrrssively worse and spread; Joint pain that got progrrssively worse and spread from condition aggravated; ankles were swollen; fingers were swollen; had serum sickness from the vaccine; could barely move / I could barely get out of bed; pain in the back of knees, every joint in the body; This spontaneous case was reported by a consumer and describes the occurrence of CONDITION AGGRAVATED (Joint pain that got progrrssively worse and spread from condition aggravated) and ARTHRALGIA (Joint pain that got progrrssively worse and spread) in a 38-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 032B21A and 047A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history information was reported.  Concomitant products included QUETIAPINE FUMARATE (SEROQUEL XR) for an unknown indication.   On 30-Mar-2021 at 1:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Apr-2021 at 3:30 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 06-May-2021, the patient experienced CONDITION AGGRAVATED (Joint pain that got progrrssively worse and spread from condition aggravated) (seriousness criterion hospitalization), ARTHRALGIA (Joint pain that got progrrssively worse and spread) (seriousness criterion hospitalization), MOBILITY DECREASED (could barely move / I could barely get out of bed) and BACK PAIN (pain in the back of knees, every joint in the body). On an unknown date, the patient experienced JOINT SWELLING (ankles were swollen), PERIPHERAL SWELLING (fingers were swollen) and SERUM SICKNESS (had serum sickness from the vaccine). The patient was hospitalized from 26-May-2021 to 27-May-2021 due to CONDITION AGGRAVATED. The patient was treated with IBUPROFEN for Joint pain, at a dose of 600 milligram three times a day and PREDNISOLONE (PREDNISOL [PREDNISOLONE]) for Pain, at a dose of 1 UNK. On 01-Jun-2021, CONDITION AGGRAVATED (Joint pain that got progrrssively worse and spread from condition aggravated), ARTHRALGIA (Joint pain that got progrrssively worse and spread), JOINT SWELLING (ankles were swollen), PERIPHERAL SWELLING (fingers were swollen), SERUM SICKNESS (had serum sickness from the vaccine) and MOBILITY DECREASED (could barely move / I could barely get out of bed) had resolved. At the time of the report, BACK PAIN (pain in the back of knees, every joint in the body) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered CONDITION AGGRAVATED (Joint pain that got progrrssively worse and spread from condition aggravated), ARTHRALGIA (Joint pain that got progrrssively worse and spread), JOINT SWELLING (ankles were swollen), PERIPHERAL SWELLING (fingers were swollen), SERUM SICKNESS (had serum sickness from the vaccine) and MOBILITY DECREASED (could barely move / I could barely get out of bed) to be possibly related. No further causality assessment was provided for BACK PAIN (pain in the back of knees, every joint in the body).     I started feeling mild pain in the back of my knees around the 6th of May, 2021. After a few days it got progressively worse and every joint in my body was in pain. I was treated with NSAIDs and they helped for a few hours each time I took them.   The pain then disappeared around May 20th, but it came back and much more aggressive and painful. I could barely get out of bed; my fingers and ankles were swollen.        Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   Most recent FOLLOW-UP information incorporated above includes: On 25-Jul-2021: Additional events (pain in back of knees and every joint in body was in pain, condition aggravated, could barely move, fingers and ankles swollen and serum sickness) and treatment drug added.event outcome updated to recovered.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.