This is a spontaneous report from a contactable consumer (patient). A 48-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot Number: EL3302, Expiration date: Unknown) via an unspecified route, administered in Right Arm on 21Jan2021 at 10:30 (48-year-old at vaccination) as a Dose 1, single for COVID-19 immunization. The patient's medical history included Cardiac arrhythmia which was diagnosed when she was 19 years old, ongoing Blood pressure high/Hypertension was there when she was a kid and had been taking blood pressure pills since high school in the late 1980s or early 1990s. She said she was on meds as a child, then taken off them, and then she had been back on them since she was 19, Hypothyroidism which was diagnosed 15 years ago, Environmental allergies since her high school, and had anaphylaxis to certain shellfish since she was 30 and was allergic to one antibiotic (No further details provided about this antibiotic), Supraventricular tachycardia and ongoing Asthma. The patient's concomitant medication(s) included ongoing fluticasone propionate, salmeterol xinafoate (ADVAIR) taken for asthma, ongoing rescue inhaler taken for asthma, nebivolol hydrochloride (BYSTOLIC) taken for hypertension and paraventricular tachycardia and unspecified flu vaccine from 2020 to unspecified date. She reported that after received 1st dose of vaccine on 21Jan2021, but not that day she had a reaction. she experienced side effects on a day after. Her asthma was out of control, so she had to take her asthma medications and inhaler for 2 times that day and the day after. She said she had a lot of allergies, but she does not usually require her medications. Her blood pressure was also pretty high the past few weeks. On an unknown date in 2021, she had increased blood pressure/ blood pressure had been high. She said she had been on meds almost 30 years and it had been under control. She said she happened to go to her doctor and seen an allergist and endocrinologist, and her blood pressure was high at these appointments. She said she checked it last night and it was very high, it was usually on the lower side while on the medication. On 22Jan2021, she has asthma complications / asthma which she hasn't had for a year had been flaring up, and she had been using her rescue inhaler a lot. She said that her asthma flared up following that night after the vaccine on 22Jan2021, and it flared up for a few days, she was not getting a lot of relief. She said she had a history of a ton of allergies, but they cleared her to get it. She said on the 22nd her asthma started flaring and was the worst on Saturday evening. She said she took Advair daily as a preventative inhaler, and her rescue inhaler she usually only used when her asthma was triggered by extreme weather, like when it was really humid or cold. She only used it when she had a respiratory cold, she hadn't used her rescue inhaler since she had a respiratory infection last year, and before that only when allergies to pollen or cats come up. She called her doctor that Saturday two days after the vaccine. It was bad Saturday. She said since just had got the vaccine, that was what they assumed it was, and it was bad enough that she almost went to the emergency room, but she took a Benadryl instead felt she might be having a nervous panic attack, then she went to bed and woke up feeling better and had slowly been getting better. It subsided in the next day or two. She took Benadryl and Claritin the next day. Sunday night, she felt better. Her asthma flared up. She said that the bottle of Benadryl was expired, and she only took one dose, the minimal amount of 7mL. She said dosing was to take 5mL-10mL but, doesn't provide a strength. She said for her rescue inhaler she doesn't know which she used, it was ProAir, which she had all over the place, so she doesn't know which one she used. She declined to provide NDC/LOT/EXP as LOT: MLN032, EXP Aug2020 for her ProAir rescue inhaler. She said she had heard that the side effects from the second dose are worse, and since she has had her blood pressure increased and asthma complication since her first dose, she wanted to make sure it was safe for her since she doesn't want to have a worse reaction. She said she would like to ask if this could be a side effect or a coincidence. She said she ran it by her doctor, and they said increased blood pressure could be from vaccine. She said she takes a blood pressure medication and had for years with no problems. She said her vaccine card was handwritten, the LOT was not written very neatly, and the NDC/EXP was not provided on her card. Her doctor attributed it to the vaccine and said it would reside in a couple of days. He advised her to still get the 2nd dose. She was asking if these are common side effects of the vaccine. She mentioned that she was supposed to get the 2nd dose of the vaccine this week. She said She stated that her second dose is supposed to be today (11Feb2021) in the evening, but because her blood pressure was increased and she had an issue with her asthma, she wanted to make sure since she was not sure if it was related or if it was a common side effect, she doesn't want to get it if it was making her blood pressure higher. She said her doctors are telling her to go ahead and get it. Reporter stated that she had also been hearing second dose was more intense, though most of her coworkers said they had flu like symptoms, which would be fine with her. No further details provided about her coworkers. On 10Feb2021, she said she took her blood pressure at work last night and it was 140/93 around 07:00 PM, then she took it again before she left work at 09:00 PM and it was 138/92. She said on medication, her blood pressure was usually 120/80s or lower 70s. She was wondering if an increase in Blood pressure, and an asthma flare up are listed side effects. She was reluctant to get the second vaccine. She was an MRI tech. The outcome of the event asthma flared up was recovering and the outcome of other event was unknown.  Follow-up attempts completed. No further information expected.