UNABLE TO WORK / SHORT TERM DISABILITY; COULD NOT SIT OR STAND FOR MORE THAN 10-15 MINUTES / COULD NOT GET UP; COULD NOT SEE / LEGALLY BLIND; BACK PAIN; ARM FELT WEIRD; KNEE ISSUES / MID AND LATERAL MENISCUS IN KNEE; This spontaneous report received from a 50 year old male patient. The patient's height, and weight were not reported. The patient's past medical history included: covid-19 (Patient had Covid in the beginning of year of 2020. He lost taste and smell. He never got his sense of smell back after that), and other pre-existing medical conditions included: Patient reported that he was in phenomenal shape before, never had any problems. He was an athlete and exercised his entire life, had no health issues or injuries. He played basketball, surfed, hike, was a runner. He never used to have to see a doctor except for his physical each year. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin, and batch number were not reported) dose was not reported, 1 total, administered on 10-MAY-2021 in right arm for covid-19 prophylaxis. Age at time of vaccination 50 years old. The batch number was not reported and has been requested. No concomitant medications were reported. On 10-MAY-2021, the patient was observed for 15 minutes after receiving the vaccine. Patient said his arm felt weird and he did arm circle for this. Patient left after about 30 minutes. The doctor told him that he would have side effects for 10-12 hours. Patient reported that he did have horrible side effects. He was really sick for 2 days, woke up in the middle of the night, on 11-MAY-2021, the patient was bed ridden, he experienced extreme back pain, was sick and he could not see through 12-MAY-2021. Patient reported that his work sent him a Covid test and it was negative. He did not go in hospital to be seen for his back pain until nothing changed and reported that it got worse. On 13-MAY-2021, patient went back to work and he could not sit or stand and could not see. He had to lay down, as the pain came every 15 minutes, and finally could not do it anymore and had to leave work. He tried to tough it out for a couple of months. Patient reported that his last working day was 28-JUL-2021. His work put him on a short term disability. At this time the patient started seeing the doctors and specialists. Patient could not see anything and could not get up. He felt better after 2 days and he could see better. Then his back began hurting and he had knee issues as well. He would try to stand, but he could not sit or stand for more than 10-15 minutes. Patient reported that his vision was going bad as well. He has seen doctors and surgeons over the last year. His knee was so bad, and his pain management team for his back told him his mid and lateral meniscus in his knee was an issue. On 02-AUG-2022, patient had knee surgery and he reported that was going pretty good with his range of motion. Patient reported that he has seen 2 orthopedic surgeons and they will not perform surgery on him for his back. He was now seeing a specialist a neurosurgeon to see if he could do anything. Patient reported that he was now also legally blind and could no longer drive. His eyesight was getting worse and reported that his health has deteriorated because of the shot.  The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient was recovering from knee issues / mid and lateral meniscus in knee, had not recovered from back pain, and could not see / legally blind, and the outcome of arm felt weird, could not sit or stand for more than 10-15 minutes / could not get up and unable to work / short term disability was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: 20220924202-covid-19 vaccine ad26.cov2.s -knee issues / mid and lateral meniscus in knee. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s). Therefore, this event(s) is considered unassessable.