tingling; Nausea; her arm that she got the shot, and her arm is really tender; Sick; Really bad migraine; Violently throwing up; Body aches; Chills; Fatigue; Sore arm; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 54 year-old female patient received bnt162b2 (BNT162B2), administered in arm left (Lot number: EW0175) at the age of 54 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Migraine" (ongoing), notes: diagnosed years ago; "Cellulitis" (unspecified if ongoing); "Cerebral dermatitis" (unspecified if ongoing). Concomitant medication(s) included: BOTOX taken for migraine (ongoing); DUPIXENT taken for seborrhoeic dermatitis; IMITREX taken for migraine; MOTRIN [IBUPROFEN]; ASPIRIN [ACETYLSALICYLIC ACID] taken for migraine. Vaccination history included: Flu shot (tingling and she thought this is not good this is how her arm with the flu shot in it felt), administration date: 01Sep2016, for Immunization, reaction(s): "destroyed her whole right arm"; Bnt162b2 (First Dose, Lot Number: ER8733 , Dosage text: Left arm), administration date: 06Apr2021, when the patient was 54 years old, for COVID-19 Immunization. The following information was reported: MIGRAINE (non-serious) with onset 28Apr2021, outcome "recovering", described as "Really bad migraine"; VOMITING (non-serious) with onset 28Apr2021, outcome "recovered" (28Apr2021), described as "Violently throwing up"; PAIN IN EXTREMITY (non-serious) with onset 27Apr2021, outcome "not recovered", described as "Sore arm"; PAIN (non-serious) with onset 28Apr2021, outcome "not recovered", described as "Body aches"; CHILLS (non-serious) with onset 28Apr2021, outcome "not recovered", described as "Chills"; FATIGUE (non-serious) with onset 28Apr2021, outcome "not recovered", described as "Fatigue"; PARAESTHESIA (non-serious), outcome "unknown", described as "tingling"; NAUSEA (non-serious), outcome "unknown", described as "Nausea"; VACCINATION SITE PAIN (non-serious), outcome "unknown", described as "her arm that she got the shot, and her arm is really tender"; ILLNESS (non-serious), outcome "unknown", described as "Sick". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of migraine, vomiting, pain in extremity, pain, chills, fatigue, paraesthesia, nausea, vaccination site pain, illness.  Additional information: Reporter stated that patient takes Botox injection every twelve weeks and 31 injections around face and the back of her head. Patient takes dupixent shot every two weeks. Reporter stated that patient got the Pfizer vaccine on Tuesday. Patient gets migraines really bad anyway, every 10-12 weeks she gets 31 Botox injections at one time. Patient tried to take Promethazine for nausea, and she threw that up plus her arm is a little more sore than last time. Patient has migraine after the vaccine passed up all the 31 Botox injections and patient took Imitrex and 800 mg of Motrin. These products didn't work on the headache after receiving the shot also mentions taking Tylenol; Aspirin; and receiving Botox injections. Reporter stated that patient has been catching water with her fingers and they started to tingling and patient thought this is not good this is how her arm with the flu shot in it felt. Reporter stated patient head was pounding so bad last night. Reporter stated patient was taking Tylenol now every six hours. It has improved and patient was getting the migraines in the morning and in the afternoon. Patient did not take previous immunization with the Pfizer vaccine considered as suspect. No additional vaccines were administered on same date of the Pfizer suspect. Patient did not go to the emergency room and physician office. Patient did not have family Medical History Relevant to AE.  No follow-up attempts are possible. No further information is expected.