Drug ineffective; COVID-19; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP).  A male patient in his 70's received BNT162b2 (BNT162B2), as dose 1, single (Batch/Lot number: unknown), as dose 2, single (Batch/Lot number: unknown), as dose 3 (booster), single (Batch/Lot number: unknown) and as dose 4 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "her husband and her contacted Covid" (unspecified if ongoing). The patient's concomitant medications were not reported.  The following information was reported: DRUG INEFFECTIVE (medically significant), outcome "unknown", described as "Drug ineffective "; COVID-19 (medically significant), outcome "unknown". The patient underwent the following laboratory tests and procedures: SARS-CoV-2 test: Positive, notes: they both tested positive and negative 3 time's; Negative, notes: they both tested positive and negative 3 time's. Therapeutic measures were taken as a result of drug ineffective, covid-19.  Clinical information: She had a consumer on the line who called for Paxlovid. She reported the reaction she had with Paxlovid and did not have any questions. She had a reaction and she took the medication for 5 days and she stopped last Friday. She said previous to this her husband and her contacted covid because they were silly and went where people were and 3 days later got Covid. Was a very mild reaction if anything and they went about their daily business and they were retired and not going to work. They confined their activities to walking in the park away from people for exercise and fresh air until they tested negative. Their son lives with them and he got Covid from them and then they got Covid back from him. They did not want to keep passing Covid back and forth forever and she said they do not build up antibodies and they could get as many times as exposed and they were healthy and her husband and her were in their 70's and their son is in his 50's and they are active and healthy. She did not want to get Covid back and she said the more times getting Covid can then get lung Covid and said who wants lung Covid. She talked to the pharmacist at the local drug store and he had been in pharmaceutical company and he was knowledgeable and he suggested to get on the antiviral and they called their doctor and he sent the prescription and they started on Monday and by Tuesday she got a terrible taste in her mouth and the taste was like a metallic taste and her husband had the metallic taste too and he went through the 5 days series better than her. She said her husband did not have the same problem. She said she thought she was doing a report by giving the information and she would get through this and she was optimistic. The pharmacist said would be beneficial and like to hear new products and she was doing this for Pfizer. Caller passed the phone to her husband (Name withheld). The husband said he was going to pass the phone back to his wife but he wanted to mention some facts that was wife did not mention. He said they were both vaccinated and boosted all with Pfizer vaccines and received two vaccines and two boosters and the second issue was they both tested positive and negative 3 times and by the third time they decided to try this antiviral drug and at that point they were in desperation.They called their primary care and the pharmacist.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.