flu-like symptoms: headache; of adverse symptoms, complications, injuries, and other adverse event; tingling in hands and feet; stomach pain; dizziness, lightheadedness; nausea; joint pain; high blood pressure; night sweats; Immune Thrombocytopenic Purpura (ITP): and developed red spots on his chest, back, arms and legs/nose bleeds/; disturbes sleep; This initial spontaneous report has been received from a lawyer regarding a case in litigation, concerning a 16-year-old male patient (pt). The pt' pertinent medical history, concurrent conditions, concomitant medications and previous drug reactions, or allergies were not reported. On 03-JUL-2019, the pt was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (dose, strength, vaccination scheme, route of administration, anatomical location lot number and expiration date were not provided), administered for preventing cancer. It has been reported that the pt sustained serious autoimmune, autonomic, and neurological Injuries as a result. It was reported that on an unknown date in 2019, (also reported as in the months receiving this vaccination), the plaintiff began to experience joint pains, daily headaches, lightheadedness, fatigue, night sweats, and difficulty sleeping. On 10-OCT-2019, the pt was vaccinated with the second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (dose, strength, vaccination scheme, route of administration, anatomical location lot number, and expiration date were not provided). On 24-OCT-2019, he experienced flu-like symptoms, had a white blister-like spot on the inside of his throat, and was taken to urgent care. Thereafter, he began experiencing frequent nosebleeds and developed red spots on his chest, back, arms, and legs. During an annual pediatric dental cleaning procedure, the pt experienced more than the usual bleeding in his gums, the bleeding continued throughout the night following the cleaning and he woke up the following morning with blood blisters inside his mouth, cheeks, and gums, he also began seeing stars, feeling extremely lightheaded, experiencing heart palpitations, and was lethargic. After hitting his leg on his bike while at a biking camp with his father, a red bruise that looked like a blood clot formed on his leg, his mother sent a photograph of the bruised leg and mouth blisters to pt's pediatrician. Immediately, the pediatrician called her and instructed her to not allow her son to ride the bike any longer or he would bleed to death and to send him to the nearest hospital as it was a medical emergency, his father drove pt to the nearest hospital, pt's platelets were extremely low at 2,000 and required medication, he was diagnosed with Immune Thrombocytopenic Purpura (ITP), the pt continued to experience nose bleeds and strong headaches, his parents took him to the emergency room near home where he was instructed to restrict his activities and dietary intake: no contact sports, no sports where he would risk getting hit, no ibuprofen (MOTRIN), do not take certain vitamins or eat vegetables and herbs to avoid anything that may affect his platelets or bleed. Thereafter, the pt was enrolled in a hematology plan and had blood tests conducted every three months. As a result of his post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt had been unable to engage in activities that a young person normally would enjoy, he was no longer able to exercise as he had previously done, he had to give up playing high school football and basketball, practicing Jiu Jitsu, and riding motocross bikes. Currently, the pt worked hard to manage his myriad symptoms, which had made it very difficult to sustain a reliable work schedule with his employer while also attending frequent doctor appointments to monitor his health. Furthermore, the pt had been unable to obtain life insurance and had been rejected by three insurance carriers because of his ITP. Based upon his chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt had been diagnosed with various medical conditions, including but not limited to ITP. The pt contended that his quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused him to develop serious and debilitating autoimmune injuries, including but not limited to ITP, resulting in pt experiencing daily headaches, disturbed sleep, dizziness, nausea, tingling in hands and feet, stomach pain, chest tightness, high blood pressure, joint pain, constant fatigue, as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which are alleged herein and all of which were caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to his quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. As a proximate result of the company's alleged wrongful acts and quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) manufacturing defects, plaintiff suffered and continued to suffer severe and permanent physical injuries and associated symptomology and suffered severe and permanent emotional injuries, including pain and suffering. Also, he had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with his autoimmune disease and other injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of his Gardasil-induced injuries, he suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and he would continue to incur those losses and expenses in the future. At the time of reporting, plaintiff had not recovered from the events. The reporter considered all the aforementioned events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL).  All the events were considered as disabling by reporter.  Upon internal review, the event of immune thrombocytopenia were determined to be medically significant.