her equilibrium was off; She said feels cold all the time now; bone and muscle in her body hurt; hands and body were jerking; she ached all over; she felt tired; rigors; shaking; muscle and joint aches/her muscles hurt; muscle and joint aches/her joints hurt; This is a spontaneous report from a contactable consumer (patient). An 81-year-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Batch/lot number: EL3247), via an unspecified route of administration at left upper arm on 21Jan2021 08:00 at single dose for covid-19 immunization.  Medical history included lymphoma from 2018. The patient's concomitant medications were not reported.  There were no additional vaccines administered on same date of the Pfizer. The patient previously took rituxan for lymphoma (Reported she had been in remission for a little over a year. She said she had received only 4 Rituxan infusions for the lymphoma before she went into remission). 12 hours post injection: she "experienced significant rigors and shaking, muscle and joint aches, her equilibrium was off at some point, she was tired, had generalized pain, and chills". She also confirmed feeling better.  She stated she heard the the second dose of the vaccine caused more reaction than the first dose and would like to validate the information. She explained the first instance she experienced rigors was after a lymphoma treatment. She believed the rigors lasted "12 hours" but was not certain because she "fell asleep and got warmed". The patient felt great all day on 21Jan2021 after receiving her first COVID-19 Vaccine dose. She said almost exactly 12 hours later, she started to have rigors. She was shaking so hard that her hands and body were jerking. Her muscles and joints were hurting, her equilibrium was off, she ached all over, she had pain, felt tired, and she had chills. The rigors started first. She said she felt really cold at the same time, so she went to bed and covered up, trying to get warmed. She fell asleep for awhile, and then woke up and went to the bathroom. When she went to get out of bed to go to the bathroom, she stood up, and every bone and muscle in her body hurt. She said she was aching all over, and her equilibrium was off. She didn't feel like getting up, and finally went to sleep to get the rigors to stop. She felt cold all the time now, but the rest of her symptoms had improved. She said it seemed like the muscle in her right leg was still pretty sore. She said she recovered from the rigors completely. She had rigors once before when she had an infusion. She clarified the infusion was Rituxan. She said she had a reaction to her first treatment of Rituxan. She said she had rigors when the Rituxan infusion was first started. She was given a couple things (but she didn't know what those things were), and she stopped shaking. She said the infusion staff waited a few minutes and tried to restart the Rituxan infusion, but she would have rigors again. She said the infusion staff tried slowing down the Rituxan infusion rate, as well. She said the Rituxan infusion normally takes 2 hours, but after 8 hours, she had only got about 20% of the Rituxan infusion, before the Rituxan infusion was stopped. She stated she had 3 subsequent Rituxan infusions at later dates, and did not have any problems with those infusions. Her first dose of the COVID-19 Vaccine was administered high up in the muscle of her left arm, close to the shoulder joint. She said the COVID- 19 Vaccine injection didn't hurt, and her left arm never got sore. She said on 30Dec2020 she had lab work done for her oncologist. She went about every other month for blood work to make sure she was still in remission. She saw her oncologist on 06Jan2021, and her oncologist said her blood work looked pretty good and was better. She asked her oncologist about the COVID-19 Vaccine, and her oncologist said she definitely wanted her to get the COVID-19 Vaccine. Her next appointment with her oncologist was in Mar2021. She said she had been seeing her oncologist every month, but her oncologist this time, wanted to try seeing her after 2 months. The events did not require a visit to emergency room or physician office. The outcome of events rigors, shaking was recovered in Jan2021. The outcome of events muscle and joint aches/her muscles hurt, equilibrium was off, aching all over, tired, bone and muscle in her body hurt, hands and body were jerking was recovering. The outcome of event feels cold was not recovered.