Achy soreness on the arm; Little temperature increase; The area warm to touch; Upper arm itchy/itching on right upper arm where vaccinated; Slight swelling/ the area was swollen; Pinkness where received the vaccination; area also was tender; This spontaneous case was reported by a nurse and describes the occurrence of PAIN IN EXTREMITY (Achy soreness on the arm), BODY TEMPERATURE INCREASED (Little temperature increase), VACCINATION SITE WARMTH (The area warm to touch), VACCINATION SITE PRURITUS (Upper arm itchy/itching on right upper arm where vaccinated) and VACCINATION SITE SWELLING (Slight swelling/ the area was swollen) in a 74-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 042L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Concurrent medical conditions included Allergy to chemicals (Patient had allergy with Bactrim - sulfamethoxazole and trimethoprim.), Peripheral neuropathy, Premature atrial contraction (Med controlled (Atenolol)) and Tremor aggravated (increased essential (head/neck) tremors). Concomitant products included PRIMIDONE for Tremor aggravated, ATENOLOL for Tremor aggravated and Premature atrial contraction, MULTIVITAMIN & MINERAL, FISH OIL, GLUCOSAMINE, GLUCOSAMINE, METHYLSULFONYLMETHANE (MSM & GLUCOSAMINE), DIPHENHYDRAMINE, PARACETAMOL, PHENYLPROPANOLAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE;PARACETAMOL;PHENYLPROPANOLAMINE HYDROCHLORIDE]) and ACETAMINOPHEN for an unknown indication.    On 31-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 07-Feb-2021, the patient experienced VACCINATION SITE WARMTH (The area warm to touch), VACCINATION SITE PRURITUS (Upper arm itchy/itching on right upper arm where vaccinated), VACCINATION SITE SWELLING (Slight swelling/ the area was swollen), VACCINATION SITE ERYTHEMA (Pinkness where received the vaccination) and INFUSION SITE PAIN (area also was tender). On an unknown date, the patient experienced PAIN IN EXTREMITY (Achy soreness on the arm) and BODY TEMPERATURE INCREASED (Little temperature increase). On 15-Feb-2021, PAIN IN EXTREMITY (Achy soreness on the arm), BODY TEMPERATURE INCREASED (Little temperature increase), VACCINATION SITE WARMTH (The area warm to touch), VACCINATION SITE PRURITUS (Upper arm itchy/itching on right upper arm where vaccinated), VACCINATION SITE SWELLING (Slight swelling/ the area was swollen), VACCINATION SITE ERYTHEMA (Pinkness where received the vaccination) and INFUSION SITE PAIN (area also was tender) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered VACCINATION SITE WARMTH (The area warm to touch), VACCINATION SITE SWELLING (Slight swelling/ the area was swollen), VACCINATION SITE ERYTHEMA (Pinkness where received the vaccination) and INFUSION SITE PAIN (area also was tender) to be probably related. No further causality assessments were provided for PAIN IN EXTREMITY (Achy soreness on the arm), BODY TEMPERATURE INCREASED (Little temperature increase) and VACCINATION SITE PRURITUS (Upper arm itchy/itching on right upper arm where vaccinated).    Concomitant medications Primidone, Atenolol, multivitamin, fish oil, glucosamine, Methylsulfonylmethane, Benadryl. Treatment details were not provided.   Most recent FOLLOW-UP information incorporated above includes: On 28-Apr-2021: Added patient allergy and  current conditions. Concomitant drugs were added, and New events were added.  outcomes of events were updated.