Patient started experiencing burning on both hands, spreaded up to their elbow on both hand.; Itching, scratching on both hands, spreaded up to their elbow on both hand; Scratching on both hands; Poison ivy; This spontaneous case was reported by a consumer and describes the occurrence of BURNING SENSATION (Patient started experiencing burning on both hands, spreaded up to their elbow on both hand.), PRURITUS (Itching, scratching on both hands, spreaded up to their elbow on both hand), SCRATCH (Scratching on both hands) and FEELING ABNORMAL (Poison ivy) in a  patient of an unknown age and gender who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No medical history was provided by the reporter.  Concomitant products included DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) from 12-Aug-2021 to an unknown date for Adverse event.    On 12-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In August 2021, the patient experienced BURNING SENSATION (Patient started experiencing burning on both hands, spreaded up to their elbow on both hand.), PRURITUS (Itching, scratching on both hands, spreaded up to their elbow on both hand), SCRATCH (Scratching on both hands) and FEELING ABNORMAL (Poison ivy). At the time of the report, BURNING SENSATION (Patient started experiencing burning on both hands, spreaded up to their elbow on both hand.), PRURITUS (Itching, scratching on both hands, spreaded up to their elbow on both hand) and SCRATCH (Scratching on both hands) had not resolved and FEELING ABNORMAL (Poison ivy) outcome was unknown.        mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosing remained unchanged.       Concomitant products were not provided.  Treatment medication was reported as some unknown steroids. Patient states that they have been in and out of the emergency room since 12 Aug 2021 The patient went to ER and was prescribe steroids and Benadryl.  Company comment: This case concerns a patient, unknown age and gender, with no relevant medical history, who experienced the non-serious, unexpected events of burning sensation, pruritus, scratch and feeling abnormal . The events occurred  on unknown date after first dose of mRNA 1273 vaccine. The patient had burning, itching, scratching on both hands, spreaded up to their elbow. Patient went to the emergency room and was prescribed with antihistamines and steroids. The rechallenge is not applicable as patient had treatment for the events. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.   This case was linked to MOD-2021-385715 (Patient Link).; Sender's Comments: This case concerns a patient, unknown age and gender, with no relevant medical history, who experienced the non-serious, unexpected events of burning sensation, pruritus, scratch and feeling abnormal . The events occurred  on unknown date after first dose of mRNA 1273 vaccine. The patient had burning, itching, scratching on both hands, spreaded up to their elbow. Patient went to the emergency room and was prescribed with antihistamines and steroids. The rechallenge is not applicable as patient had treatment for the events. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.