stressed; not eating or drinking like she should; Almost a dizzy and faint feeling; temperature was at 100; shortness of breath; hot and clammy; tiredness/ fatigue; This is a spontaneous report from a contactable nurse (patient). A 30-year-old female patient received BNT162B2, via an unspecified route of administration, administered in right deltoid muscle on 04Sep2021 13:30 (Batch/Lot Number: FC3182; Expiration Date: 31Oct2021; NDC: 59267-1000-03) at the age of 30 years old as dose 2, 0.3 ml single for COVID-19 immunization. Medical history included Anxiety. She has history of it. It got worse this past year because she has had two miscarriages this past year and it exacerbated the anxiety. That was her reason for getting the vaccine, she wanted to try again to get pregnant later on. No family medical history relevant to adverse events. There is no asthma or diabetes. There is anxiety and depression in the family. Concomitant medication(s) included vitamin c [ascorbic acid]; vitamin d nos; ascorbic acid, betacarotene, calcium sulfate, colecalciferol, cyanocobalamin, ferrous fumarate, folic acid, nicotinamide, pyridoxine hydrochloride, retinol acetate, riboflavin, thiamine mononitrate, tocopheryl acetate, zinc oxide (PRENATAL VITAMINS) taken for unspecified indications, start and stop dates were not reported. Clarified that she is not pregnant. Prior Vaccinations included Tetanus booster in Nov2020 (the last thing she had). No adverse events following prior vaccinations (So far so good with every vaccine she has had). The patient previous received first dose of BNT162B2 (Batch/Lot Number: FA6780; Expiration Date: 30Sep2021; NDC: 59267-1000-03), 0.3ml injected in left deltoid on 07Aug2021. Someone told her if she switched arms the side effects aren't as bad, she thinks they lied. Received Pfizer COVID Vaccine because part of it was wanting to get pregnant, but the main reason was being school nurse and wanting to protect herself. Patient wanted to double check about possible side effects to the Pfizer vaccine. She went on 04Sep2021 at 1:30 PM (Saturday) and got second dose of Pfizer COVID vaccine. She experienced shortness of breath, hot and clammy (hot and clamminess) on 07Sep2021 (Tuesday) after receiving the vaccine. She was fine over the weekend. She experienced tiredness and fatigue and went back to work on Tuesday. Her temperature was at 100 (also reported as degree C). Was asking if others have reported a similar reaction to the vaccine and wanted to know how long she would expect for her side effects to be back to normal. The patient had been feeling ok, but the weekend was better when she could sleep and relax. She has been tired and fatigued. Being back at work on Tuesday, Wednesday, and Thursday she has been short of breath. More short of breath than usual. She is a school nurse and has to wear a mask. She is not sure if it was stress. She has checked her oxygen saturation and it is 98%. She was more tired than usual on Saturday and Sunday, started about 6PM on 04Sep2021. It was not serious, but noticeable. She doesn't have to go to ER. Short of breath started on 07Sep2021 (Tuesday), when she was back to at work when she was running around. She noticed she couldn't catch her breath like normal. As a nurse, she panicked and worried about blood clots. It was ongoing and persisting. It was noticeable with exertion. She was worried. Reporter seriousness for short of breath was medically significant. She would be at hospital if disabling. Reporter seriousness for hot and clammy was not serious. Hot and clammy also started on 07Sep2021 (Tuesday). Her temp was sitting around 100. That is a mixture of dehydration and wearing a mask at work. Her temperature has been around 100 at work and the hot and clammy feeling set in. It was ongoing especially with exertion. She feels it when at work and running around. Almost a dizzy and faint feeling hit her today (also reported as on 09Sep2021) and it worried her. Being so stressed she was not eating or drinking like she should, and she knows that was part of it. Work stress is not helping. She came home early from work because she was not feeling well. Events did not require a visit to Emergency Room nor Physician Office. She wanted to avoid that at all cost with how bad COVID is. Outcome of events shortness of breath, hot and clammy and fatigue was not recovered; while other events was unknown. Event relatedness of Pfizer COVID Vaccine with tired and fatigued, hot and clammy - Related. Causality: Tired and fatigued, Short of breath, Hot and clammy: Yes, because it has happened since she got it. She has a lot of stress and anxiety going on too, but it was exacerbated after the vaccine.  Relatedness of drug to reaction(s)/event(s): tired and fatigued, Short of breath, hot and clammy (Source of assessment: Primary Source Reporter, Method of assessment: Global Introspection) - Drug result: Related.; Sender's Comments: Based on the information currently available, a possible contributory role of the suspect vaccine BNT162B2 or comirnarty in triggering the onset of shortness of breath cannot be excluded.The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees and Investigators, as appropriate.