little spots on her left arm; bump with a rash left arm/a rash above the injection site in the left arm; bump with a rash left arm; numbness in her left arm; pain in her upper arm and shoulder/now more on than off, at the top of the shoulder; pain in her upper arm/severe pain in her arm/thought it was in the upper biceps/left arm and left leg feel weak/they are not actually weak and they ache on and off; left arm and left leg feel weak/they are not actually weak and they ache on and off; left arm and left leg feel weak/they are not actually weak and they ache on and off; tingling in her arm; discoloration left arm; horrible migraine; severe pain/10% by the nerve/thinks it may be a nerve; arm felt inflamed and burning alongside the upper arm; left knee and ankle have numbness; This is a spontaneous report received from a contactable physician (patient's relative). This physician reported on behalf of his 60-year-old niece (patient) who the second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: Unknown), via an unspecified route of administration in the left arm on 05Apr2021 as single dose for COVID-19 immunization. The patient was not enrolled in the clinical trial. Medical history included migraine "for years", and anemia. The patient's concomitant medications were not reported. The patient previously received the first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: Unknown), via an unspecified route of administration in Mar2021 as single dose for COVID-19 immunization. On 08Apr2021, the patient experienced bump with a rash left arm. In Apr2021, she experienced numbness in her left arm, tingling in her arm, discoloration left arm, "pain in her upper arm and shoulder/now more on than off, at the top of the shoulder", horrible migraine, left arm and left leg feel weak/they are not actually weak and they ache on and off. On 28Apr2021, she had little spots on her left arm. On an unspecified date in 2021, the patient experienced left knee and ankle have numbness, severe pain/10% by the nerve/thinks it may be a nerve, and "arm felt inflamed and burning alongside the upper arm". The clinical course of events was as follows: The physician reported that his niece had both vaccinations, referring to the Pfizer COVID 19 vaccine; the last dose was 05Apr2021. The physician stated that she developed bump with a rash left arm 3 days after the second vaccination (08Apr2021), and he advised treatment with Benadryl. The physician stated that 2 weeks after the second vaccine dose, she reported numbness in her left arm (which is the arm she received the vaccine in). Then 4 weeks later she reported pain in her upper arm and shoulder that was "much worse" and that pain in the arm has gotten worse and described as "severe" and 90% of the pain was in the upper arm where the vaccination was given and 10% by the nerve, and that the arm felt inflamed and burning alongside the upper arm. She also described a feeling of "lightness" in her knees, legs, and toes, and a "slight tingling".  She had numbness and tingling starting a couple of weeks after the second vaccine dose. Now she is in severe pain. she had little spots on her left arm that started on Monday 28Apr2021 three weeks and two days after the vaccination. She experienced severe pain in the arm at the top of the shoulder, now is more on than off, and numbness in the arm - like she slept on it but she didn't. She also reported her left knee and ankle have numbness on the same side as the vaccination in left arm and her leg feel weak - but they are not actually weak and they ache on and off. The patient also mentioned that she had no headache after the first dose but she had a horrible migraine and had recovered from this headache since she has a history of migraine and takes Topamax. The physician stated that he is unsure exactly when all of these events started but they are ongoing. He is most concerned about the severe pain and mentioned that she did see her primary care physician and he put her on a Medrol dose pack as he thinks it may be a nerve. The patient mentioned that they did a CBD and her white cell count was 5000 but added the doctor told her not to worry unless it was greater than 7000 but the physician stated it is fine. The physician would like to know if there have been any reports of prolonged pain with the vaccine. The physician does not think it could be related to the vaccine and stated that he is going to have her see a neurologist. The physician also mentioned that his niece developed a rash above the injection site in the left arm and was started on a Medrol dose pack. The clinical outcomes of the event horrible migraine was resolved on an unspecified date in 2021, the events numbness in her left arm, "pain in her upper arm and shoulder/now more on than off, at the top of the shoulder", "pain in her upper arm/severe pain in her arm/thought it was in the upper biceps/left arm and left leg feel weak/they are not actually weak and they ache on and off" and tingling in her arm were not resolved; and the events bump with a rash left arm, left knee and ankle have numbness, "left arm and left leg feel weak/they are not actually weak and they ache on and off", little spots on her left arm, "severe pain/10% by the nerve/thinks it may be a nerve" and "arm felt inflamed and burning alongside the upper arm" were unknown.