nausea/nausea is getting worse even with the medications/nausea is exasperated more/nausea but it is getting bad/nausea got worse after her second vaccine/it has persisted; feeling unwell/it is a weird feeling; IBS or irritable bowel syndrome and interstitial cystitis or painful bladder syndrome; IBS or irritable bowel syndrome and interstitial cystitis or painful bladder syndrome; congested; This is a spontaneous report received from a contactable consumer (patient) reported for herself. A 70-years-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Lot number: EW0178, Expiration date: unknown) via an unspecified route of administration, administered in right upper arm on 09Jun2021 around 11 am to 12 pm (age at vaccination was 70 years) as 2nd dose, single dose for COVID-19 immunization. Medical history included irritable bowel syndrome from 2015 and ongoing and it was not as bad as it was before, but that when someone has that they are in a lot of pain and they poop a lot, it was terrible and it was the worst enemy and interstitial cystitis (painful bladder syndrome) from 2017 and ongoing and it was kind of hard to know when that affects her because it was in the same place as the IBS and she did not know who was doing what to her half of the time and it took a long time for them to figure out what that was. The patient did not have any family medical history relevant to adverse event. Concomitant medication included dicyclomine taken for an unspecified indication. The patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Lot number: EW0182, Expiration date: unknown) via an unspecified route of administration, administered in left upper arm on 19May2021 (age at vaccination was unknown) as 1st dose, single dose for COVID-19 immunization and had no reaction. The caller stated she received the second dose of the Pfizer covid 19 vaccine on 09Jun2021. The caller stated she had a medical history of IBS and got nausea all the time. The nausea was getting worse even with the medications. The nausea was exasperated more. She was feeling unwell noting that it was a weird feeling. She had interstitial cystitis or painful bladder syndrome. She wanted to know whether there were many people that experienced side effects and asked about side effects in general. The caller asked if the vaccine could cause her nausea medications not to work anymore. The caller stated that she received the second shot on 09Jun2021 (last Wednesday as reported) and did not feel too bad. What had been bothering her was that she had a lot of problems, like IBS and interstitial cystitis that she took medications for because she had a lot of nausea and stuff. Her nausea was not going away even with her medications and she had been feeling unwell. She wanted to know if that would exacerbate any symptoms from the garbage that she had. The caller clarified that she had called in regards to the Pfizer BioNtech COVID-19 vaccine. The caller stated that she was congested right now. The caller stated that most of the time she had nausea but it was getting bad. She had IBS or irritable bowel syndrome and she also had interstitial cystitis, which the caller stated that the Clinic called it painful bladder syndrome and said that it was when she had all the symptoms of a bladder infection but she did not had an actual infection. The caller stated that she had double the problems in the bottom, and that her nausea should have gone away because she took medication when she needed it. The caller stated that since she got the vaccine, her nausea had not gone away, and it was the worse thing to be nauseous all the time, but it was a good way to lose weight. The caller stated that her nausea got worse after her second vaccine but it was not right away though. She stated that she went to work yesterday and had to leave because she got so nauseous there and she left because of it. The nausea was ongoing and would not go away. The caller confirmed it had persisted. The caller asked if there were many people with side effects. The caller stated that she takes Ondansetron, 4mg tablets, 1 tablet four times a day, for her nausea, but it has not been working. No additional vaccines were administered on same date of the Pfizer Suspect. The patient did not require a visit to Emergency Room or Physician Office due to the adverse events. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. No relevant tests were done. There was a product complaint. The outcome of event nausea was not resolved. The outcome of the other events was unknown.  Follow-up (15Jun2021): New information received from a contactable consumer (patient) reported for herself included: Updated the details regarding the first and second dose of vaccine, medical history, concomitant medication, treatment medication, clinical course and product complaint.