severe allergic reactions/she developed the allergy; throat itching; tingling sensation/she felt tingling all the way up to her face; itching and the itching was going to her ears; facial swelling; rash; swelling; was feeling tingling in her throat; states her blood pressure was going up and stayed high at 180; mitral valve regurgitation; heart palpitations/Heart racing; chest tightening/chest was bothering; she couldn't breathe; Felt dizzy; felt like a panic attack; This is a spontaneous report from a contactable consumer (patient). A 44-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection),  via an unspecified route of administration, administered in right arm on 25Mar2021 (Batch/Lot number was not reported) (at the age of 44-years-old) as dose 1, single for COVID-19 immunisation. Medical history included ongoing immunocompromised, non-Hodgkin's lymphoma (chemotherapy for non-Hodgkin's lymphoma prior to the Pfizer COVID Vaccine), had allergies before/she had a mild allergy. There were no concomitant medications. Patient had the 1st dose of the Pfizer COVID 19 vaccine last 25Mar2021 and never received the 2nd dose due to severe allergic reactions. Patient's doctor advised her not to get the 2nd dose. She had throat itching and tingling sensation, facial swelling, heart palpitations, and rash. This week (in 2021) she was diagnosed with mitral valve regurgitation. Patient had a severe allergic reaction and ended up in the emergency room and went to see her cardiologist because she was feeling palpitations and this happened after the vaccine. Patient stated they did an echo in the emergency room. She was not admitted to the hospital for an overnight stay. At minute 29 after receiving the vaccine, by the time she walked to the car 28-29 minutes later, she developed the allergy and it began with her throat itching and she had allergies before and went to the nurse to tell her and said she had a mild allergy and was feeling tingling in her throat and they gave her Benadryl. Then 15 minutes passed, and she was not better and was itching. The itching was going to her ears and she felt tingling all the way up to her face and they gave her another Benadryl and she said she felt fine other than a mild allergy and asked to call her sister to come pick her up because she had had two Benadryl and would fall asleep. Patient stated she was facing down and looked up and the nurse said her face was swelling and to go to the emergency room for observation and was put on a stretcher and she said she felt fine. They took her to the emergency room and the allergy started progressing super-fast and started the same tingling in her throat and felt that through her entire body, had a rash, swelling and thought she was going to die. About two weeks afterwards the allergy kicked her butt so badly that afterward she could not catch her breath to walk and was not wanting to go back to her HCP and did not want to walk and her chest was bothering her and breathing was bothering her for a while. In 2021, the palpitations began and she was feeling them while she was there and her chest tightening and her heart racing and felt like she couldn't breathe and thought she was going to die and kept telling her HCP that she had allergies before her entire life but never experienced this and felt it in her chest. In Mar2021, her blood pressure was going up and stayed high at 180 something and her blood pressure is always consistent at 120 or 124 and she had never seen the numbers like that until she got the Pfizer COVID vaccine; states she does not still have chest tightness. Her high blood pressure stayed for about two weeks and she did not know that but went to her immunologist and the machine was broken and she had not seen her other HCP at the hospital but kept checking her blood pressure and it stayed high. The palpitations she had after the Pfizer Covid vaccine and she saw her primary care physician about maybe 3 weeks ago again and felt dizzy and had to pull over the interstate and it was just a weird feeling and she requested to see the cardiologist. She had her port for her chemo removed and while she was doing the intake for that they asked her about her vaccine status before she went in for port removal and she did not know what happened but had what felt like a panic attack and her HCP and anesthesiologist said she just kind of relieved that moment and she was not vaccinated at that time. She went to see her HCP and was really nervous about taking the Pfizer COVID vaccine and the palpitations are still ongoing and she felt it at night.  States she wore a heart monitor for about a week and they did the echo last week and her cardiologist told her yesterday it was regurgitation of the heart valve and is mitral valve regurgitation. She called her oncologist this morning to ask for information on her echo from last year (2020) to see if the results of her recent echo were new or not new and needed the baseline to see what happened and they said she did not have that before on her previous echo. Outcome of itching, facial swelling was recovered on 25Mar2021, chest tightening and panic attack was recovered in 2021, mitral valve regurgitation was unknown while rest of events was unknown.   Information on the lot/batch number has been requested.