hepatitis virus become negative; first COVID immunization eradicated the hepatitis B antigen; hepatitis virus become negative; first COVID immunization eradicated the hepatitis B antigen; This is a spontaneous report received from a contactable reporter(s) (Other HCP). The reporter is the patient.  A 68 year-old male patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) at the age of 68 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Cholesterol" (unspecified if ongoing), notes: Verbatim: Cholesterol; "Diabetes mellitus" (unspecified if ongoing), notes: Verbatim: Diabetes mellitus.; "Blood pressure high" (unspecified if ongoing), notes: Verbatim: Blood pressure high; "hepatitis B" (unspecified if ongoing), notes: You know, I was a registered nurse, you know it came in to my mind oh my god almost 40 years, I was positive, I had all this precautions and you know like I remain single, I feel so isolated I had that kind of you know isolation feeling and I had that kind complexity, I feel like, I am retired, I am happier. Concomitant medication(s) included: INSULIN. The following information was reported: HEPATITIS B TEST NEGATIVE (non-serious), THERAPEUTIC RESPONSE UNEXPECTED (non-serious), outcome "unknown" and all described as "hepatitis virus become negative; first COVID immunization eradicated the hepatitis B antigen". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Concern: Nurse (Retired Registered Nurse) stated, "I am just reporting a good side effect of the Pfizer vaccine, because I read under this paper that 'bacteriopolis' (Further clarification unknown) is doing a research now and he is saying that mRNA vaccine is effective to them, to the HIV vaccine somehow, that is what he said, now what happen to me is that, I have positive hepatitis B (Intent Medical history) and that was like almost 40 years and the doctor told me that I might be like that for the rest of my life but as long as the viral load is low and I know they are monitoring that, you know it is safe, we just follow up your liver test and liver scan, that is what you she was saying and then somehow this summer suddenly the hepatitis virus become negative, so I was surprised, it became like that, because all this time, within I have the physical exercise it was always positive, so the doctor said that, okay, let just double check again, then he said (incomplete sentence), so after 2 month, oh not only that I developed antibody against hepatitis, so I was little surprised because, soon I realized that the first test was taken after I took the first COVID immunization, first COVID immunization eradicated the hepatitis B antigen and then you know it looks like the second injection of Pfizer, it created antibody against hepatitis B, seeing that doctor was surprised and he said that like ahead, so doctor said it might be it is a surprising side effect."When paraphrased the concern: Nurse stated, "So you know the second vaccine, again I was surprised because also I had antibody hepatitis B (incomplete sentence), my doctor was also surprised, so you know today, I went to get my booster, I said you know this vaccine is a miracle and may be in future it will treat all kind of viral infection, Hepatitis B or HIV or you know all kind of virus you know, I was just happy to tell you, I know it is not a right to act but this is the only way I can express my thanks to the Pfizer and you folks." Nurse further stated, "You know it is so high for among (ethnicities withheld), so I hope, it is really good unexpected effect." Nurse was informed about the role of Pfizer Drug Safety Department. Nurse further stated, "You know, I was a registered nurse, you know it came in to my mind oh my god almost 40 years, I was positive, I had all this precautions and you know like I remain single, I feel so isolated I had that kind of you know isolation feeling and I had that kind complexity, I feel like, I am retired, I am happier." Age: Nurse stated, "I was 67 last year and this year I am 68 this year when I got my booster." (Further not clarified, hence not captured in tab). Weight: Nurse stated, "I think I am 156 pounds." (Further not clarified, hence not captured in tab). LOT: The first dose last the LOT product. The booster shot today is its like 80051 then I cannot read this, oh this is the LOT ok wait now LOT# is FL3198 (Captured as provided) (name) pharmacy." Other Medical condition: Nurse stated, "I have Diabetes mellitus from past around 25 years." Concomitant medication: Nurse stated, "I have so much you known, I have insulin, I have hypoglycaemic medication (Further not clarified) high blood pressure and cholesterol medication and lot of vitamin (Further not clarified)."Lab Test: Nurse stated, "I had routine lab work like lab test 3 month or 4 month CBC you know when you go to doctor and they do basal metabolism kind of things like that." (Further clarification unknown). When probed for any further help: Nurse stated, "Ok I think it will help other people you know so it will be like that the Pfizer longer live, god bless of all."  The lot/batch number is not available despite the follow-up attempts made. Follow-up attempts completed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200008872 same patient, different doses and events