feeling paralyzed in leg/more paralyzed and couldn't walk; feeling paralyzed in leg/more paralyzed and couldn't walk; feeling paralyzed in leg/more paralyzed and couldn't walk; feeling weakness in legs; Feeling so tired and fatigued because the patient did not sleep last night; Arm did hurt; Speech got slurred; Got a little light headed; did not sleep last night; This is a spontaneous report received from a contactable reporter (Consumer or other non-HCP). The reporter is the patient.  This 62-year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 06Jan2022 15:30 (Lot number: FC3197 or FL3197) at the age of 62 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Neurocardiogenic syncope", start date: 2014 (ongoing); "periodic paralysis", start date: 2007 (ongoing); "Myasthenia gravis" (ongoing). Concomitant medication(s) included: MIDODRINE (ongoing); KEVEYIS taken for paralysis (ongoing); PYRIDOSTIGMINE BROMIDE EXTENDED RELEASE, start date: 2014 (ongoing); POTASSIUM taken for paralysis (ongoing). The following information was reported: CONDITION AGGRAVATED (medically significant), PARALYSIS (medically significant), GAIT DISTURBANCE (medically significant) all with onset 06Jan2022 20:00, outcome "not recovered" and all described as "feeling paralyzed in leg/more paralyzed and couldn't walk"; MUSCULAR WEAKNESS (non-serious) with onset 06Jan2022 20:00, outcome "not recovered", described as "feeling weakness in legs"; DYSARTHRIA (non-serious) with onset 06Jan2022, outcome "recovered" (06Jan2022), described as "Speech got slurred"; DIZZINESS (non-serious) with onset 06Jan2022, outcome "recovered" (06Jan2022), described as "Got a little light headed"; SLEEP DEFICIT (non-serious) with onset 06Jan2022, outcome "unknown", described as "did not sleep last night"; FATIGUE (non-serious) with onset 06Jan2022 20:00, outcome "unknown", described as "Feeling so tired and fatigued because the patient did not sleep last night"; PAIN IN EXTREMITY (non-serious) with onset 06Jan2022, outcome "recovering", described as "Arm did hurt". The events "feeling paralyzed in leg/more paralyzed and couldn't walk", "feeling paralyzed in leg/more paralyzed and couldn't walk", "feeling paralyzed in leg/more paralyzed and couldn't walk", "feeling weakness in legs", "speech got slurred", "got a little light headed", "did not sleep last night", "feeling so tired and fatigued because the patient did not sleep last night" and "arm did hurt" were evaluated at the physician office visit. Therapeutic measures were taken as a result of condition aggravated, paralysis, gait disturbance. Clinical course: After receiving her first dose Adult Pfizer Covid Vaccine (lot number either FC3197 or FL3197) at 15:00 on 06Jan2022, the patient waited thirty minutes at the vaccine site and felt pretty okay. On 06Jan2022, the patient got a little light-headed as her first symptom, and she stayed at the [withheld] because she didn't feel safe (by herself). On 06Jan2022, the light-headedness went away 45 minutes later. By 20:00 on 06Jan2022, the patient started feeling weakness in legs. With feeling weakness in legs, the patient tried to get up and ambulate, it wasn't really good. The patient states to not misunderstand the difference between permanent paralysis and temporary paralysis. By 20:00 on 06Jan2022, the patient started feeling this buzzing feeling and then feeling paralyzed in leg. The patient has the periodic paralysis and takes drug, Keveyis. The patient drank a bunch of high dose Potassium, but she kept getting more paralyzed. Over a period of 2 hours, the patient got more and more paralyzed and couldn't walk. Then the patient's speech got slurred and it went away completely and lasted for 30 minutes on 06Jan2022. By 22:49 on 06Jan2022, the patient called poison control to see if it was something in the Adult Pfizer Covid Vaccine. The patient was on the phone for 20 minutes and took more potassium. The potassium kicked in, the potassium offsets the paralysis, this happens from a shift in potassium. The poison control wanted to see if something in the Adult Pfizer Covid Vaccine shifted the patient's acid balance in the patient's blood because the patient has a molecular disease and molecular balance happens in the cells. Poison control said if there was a shift molecularly, something must have pushed potassium from inside the cell to outside the cell. While staying on the phone with Poison Control, the patient's goal was to get her walker and making sure the paralysis did not move up to her lungs. The patient stated the paralysis did not move up to her lungs and the paralysis got better while on the phone with poison control. The poison control did not know if the paralysis was going to possibly move up on the patient's body. Therefore, the patient stayed up without going to sleep and she was okay this morning (07Jan2022). The patient is feeling so tired and fatigued because she did not sleep last night, 06Jan2022.  The patient stated that her arm did hurt began on 06Jan2022 and was more hurting this morning. Then she also stated the arm hurting is getting better, a lot better. The patient stated that she will receive the second vaccine because she is not afraid; it could be worse or could be better, but she does not think will be life threatening.