Follicular Eczema; very bad rash/started on her face then spread to neck, arm, back, inner thighs and behind her knees and slowly spread on her body/Rash was also on shoulder; swelling; rash was inflamed and red; rash was inflamed and red; infection in her nostril/nostril infection, redness; infection in her nostril/nostril infection, redness; nose reaction which looked yellowish; Swelling and red was on the face; the yellow discharge on the side of her lip; in left thigh; This is a spontaneous report from a contactable consumer (patient). A 51-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration in left thigh on 26Apr2021 at 08:20 (at the age of 51 years old; Lot Number: EW0176, unknown expiration) as 2nd dose, single for COVID-19 immunization. The patient medical history was not reported. There were no concomitant medications.  The patient also received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) via injection in left thigh on unspecified date (Lot Number: ER2613, unknown expiration) for COVID-19 immunization at the age of 51 years old. On 26Apr2021 at 08:20, the patient received her second dose of Pfizer COVID vaccine. On 27Apr2021, the patient developed a very bad rash in the late afternoon that is ongoing and is getting worse every day and not better. It started on her face then spread to neck, arm, back, inner thighs and behind her knees and slowly spread on her body. The rash kept adding body parts. Rash was also on shoulder. The patient talked about swelling, but not sure where it was and if it was related to rash. The rash was inflamed and red. The patient also has infection in her nostril/nostril infection, redness. Infection started at same time as rash. The patient sought medical help from two doctors and was treated with ointments and medications including Benadryl and a completed course of antibiotics. Antibiotics helped with the infection. The swelling went down. The patient clarified that she was given antibiotic for nose reaction which looked yellowish. Then it moved onto her face around her lip under her nose. Swelling and red was on the face. She did not have a fever. Dermatologist gave her ointment and she started another antibiotic for 1 day and then stopped because she was getting other side effects. She continued on the antibiotic ointment for around the lip because she was forming the same infection as 4 weeks ago. She is getting back to square zero. She said the ointment for her face and skin took away the yellow discharge on the side of her lip. She reported that the rash was increasing. She stated that other things were getting temporary relief from the antibiotic, the infection, but then it kept coming back. The infection was better with the ointment, but she is not sure if will stay better. The patient was asking for recommendations on how to manage as her doctors did not know how to treat. The patient was referred back to her doctor and was told that her doctor could call Pfizer or the CDC. Upon investigation on 14May2021, biopsy of left wrist was given name dermatitis involving hair follicle, Follicular Eczema. That was what doctor's best guess.  Outcome of the events was unknown.   No follow-up attempts are possible. No further information is expected.