Blood pressure went up to 250/160; Pulmonary edema; Seizure; Shortness of breath, Could not breathe, Stopped breathing; he has not been back to work full-time; This spontaneous case was reported by a consumer and describes the occurrence of DYSPNOEA (Shortness of breath, Could not breathe, Stopped breathing), SEIZURE (Seizure), BLOOD PRESSURE INCREASED (Blood pressure went up to 250/160) and PULMONARY OEDEMA (Pulmonary edema) in a 48-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 013F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Kidney transplant.    On 14-Dec-2021 at 3:30 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 15-Dec-2021, the patient experienced DYSPNOEA (Shortness of breath, Could not breathe, Stopped breathing) (seriousness criteria hospitalization and life threatening). On 26-Dec-2021, the patient experienced SEIZURE (Seizure) (seriousness criteria hospitalization, medically significant and life threatening). On an unknown date, the patient experienced BLOOD PRESSURE INCREASED (Blood pressure went up to 250/160) (seriousness criteria hospitalization and life threatening), PULMONARY OEDEMA (Pulmonary edema) (seriousness criteria hospitalization, medically significant and life threatening) and IMPAIRED WORK ABILITY (he has not been back to work full-time). The patient was hospitalized from 15-Dec-2021 to 16-Dec-2021 due to DYSPNOEA, then from 26-Dec-2021 to 29-Dec-2021 due to BLOOD PRESSURE INCREASED, PULMONARY OEDEMA and SEIZURE. At the time of the report, DYSPNOEA (Shortness of breath, Could not breathe, Stopped breathing), SEIZURE (Seizure), BLOOD PRESSURE INCREASED (Blood pressure went up to 250/160), PULMONARY OEDEMA (Pulmonary edema) and IMPAIRED WORK ABILITY (he has not been back to work full-time) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: 250/160 (High) blood pressure went up to 250/160.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       The concomitant history was not reported. The treatment history was not provided. Patient mentioned that was a kidney transplant patient, and experienced life-threatening events, . Later on, 26-Dec-2021 again patient reported that stopped breathing and also had a seizure and admitted to hospital second time foron 15-Dec-2021 around 10:00 am patient had to go emergency room due to shortness of breath and he could not breathe and was discharged on16-Dec-2021 four days upto 29-Dec-2021. While patient was in hospital his blood pressure went up to 250/160 and was diagnosed with Pulmonary edema, further reported that patient has not been back to work full-time. patient also conveyed he's gradually getting better. This is a spontaneous case concerning a 48-year-old male patient with medical history Kidney transplant,,who experienced the serious unexpected AESI events of Seizure and Pulmonary oedema  and serious unexpected  events  of Dyspnoea, Blood pressure increased, Impaired work ability,after administration of the first dose of mRNA-1273 (Spikevax).The medical history Kidney transplant remains a confounder.The benefit-risk relationship of mRNA-1273 (Spikevax) Vaccine is not affected by this report Limited information regarding these events has been provided at this time case awaiting follow up; Sender's Comments: This is a spontaneous case concerning a 48-year-old male patient with medical history Kidney transplant,,who experienced the serious unexpected AESI events of Seizure and Pulmonary oedema  and serious unexpected  events  of Dyspnoea, Blood pressure increased,,after administration of the first dose of mRNA-1273 (Spikevax).The medical history Kidney transplant remains a confounder.The benefit-risk relationship of mRNA-1273 (Spikevax) Vaccine is not affected by this report.