LAYERS OF PUSTULES ON TOP OF PUSTULES ON HER LEFT ARM, PUSTULES STARTED LEAKING OUT; LESIONS ON HER RIGHT FOREARM AND WRIST, LESIONS CONTINUING TO SPREAD, LESION ON HER INTERIOR LOWER RIGHT LEG JUST ABOVE ANKLE; SKIN PEELED OFF ON THE LEFT FOREARM,  SKIN PEELING FROM OTHER LESIONS; LESIONS ON HER RIGHT FOREARM AND WRIST,  LESION ON HER INTERIOR LOWER RIGHT LEG JUST ABOVE ANKLE; RASH BOTH RIGHT AND LEFT FOREARMS, LEFT TORSO, CHEST, LEFT BREAST, RASHY SYMPTOMS" ON BOTH BUTTOCKS AND HIPS AND BOTH UPPER THIGHS, RASH ON THE BACK OF HER NECK, RASH ON FACE; This spontaneous report received from a patient concerned a 55 year old female. The patient's height, and weight were not reported. The patient's past medical history included psoriatic arthritis, premature atrial complexes, microscopic colitis, psoriasis, partial knee replacement, total knee replacement, three tumor removals, complete hysterectomy, and clostridium difficile colitis, and concurrent conditions included dilaudid allergy, rare alcohol use, cigarette smoker, and nsaid allergy, and other pre-existing medical conditions included the patient had no known drug abuse or illicit drug usage and no egg allergy. The patient experienced itchiness and rash when treated with influenza vaccine, and itchiness when treated with codeine. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 202A21A, and expiry: 23-JUN-2021) dose was not reported, administered on 18-MAY-2021 for prophylactic vaccination. Concomitant medications included diltiazem, diphenhydramine hydrochloride, ergocalciferol, metoprolol succinate, ubidecarenone, and vitamin b complex. On 20-MAY-2021, the subject experienced lesions on her right forearm and wrist, lesion on her interior lower right leg just above ankle. On 20-MAY-2021, the subject experienced rash both right and left forearms, left torso, chest, left breast, rashy symptoms" on both buttocks and hips and both upper thighs, rash on the back of her neck, rash on face. On 22-MAY-2021, the subject experienced layers of pustules on top of pustules on her left arm, pustules started leaking out. On 22-MAY-2021, the subject experienced lesions on her right forearm and wrist, lesions continuing to spread, lesion on her interior lower right leg just above ankle. On 22-MAY-2021, the subject experienced skin peeled off on the left forearm, skin peeling from other lesions. Laboratory data (dates unspecified) included: Laboratory test (NR: not provided) slightly elevated sodium levels and high triglycerides. Treatment medications (dates unspecified) included: calamine/glycerol/zinc oxide, methylprednisolone, and hydrocortisone. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from rash both right and left forearms, left torso, chest, left breast, rashy symptoms" on both buttocks and hips and both upper thighs, rash on the back of her neck, rash on face, layers of pustules on top of pustules on her left arm, pustules started leaking out, lesions on her right forearm and wrist, lesions continuing to spread, lesion on her interior lower right leg just above ankle, skin peeled off on the left forearm, skin peeling from other lesions, and lesions on her right forearm and wrist, lesion on her interior lower right leg just above ankle. This report was non-serious.