Caller has had three doses of the Pfizer BioNTech Covid 19 vaccines/tested positive for Covid; Caller has had three doses of the Pfizer BioNTech Covid 19 vaccines/tested positive for Covid; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 78-year-old female patient received BNT162b2 (BNT162B2), on 29Jul2021 as dose 1, single (Lot number: EW0175), on 09Sep2021 as dose 2, single (Lot number: EW0178) and on 14Apr2022 as dose 3 (booster), single (Lot number: FP4554) at the age of 77 years for covid-19 immunisation. The patient's relevant medical history included: "last fall was diagnosed with lung cancer" (unspecified if ongoing); "had radiation treatment", start date: Feb2022, stop date: Feb2022; "had emergency gallbladder surgery in Dec2020", start date: Dec2020 (unspecified if ongoing); "Initially was going to do surgery to remove the small spot in lung", start date: 04Jan2022 (unspecified if ongoing), notes: Initially going to do surgery to remove the small spot in lung, 04Jan2022 was scheduled for surgery. There were no concomitant medications. The following information was reported: VACCINATION FAILURE (medically significant), COVID-19 (medically significant) all with onset 28Jul2022, outcome "unknown" and all described as "Caller has had three doses of the Pfizer BioNTech Covid 19 vaccines/tested positive for Covid". The patient underwent the following laboratory tests and procedures: Antibody test abnormal: (unspecified date) Antibody test abnormal, notes: caller has very unusual antibodies and antigens in caller's blood; Blood test: (unspecified date) everything came back fine, notes: screen blood test before the surgery, and everything came back fine; (unspecified date) all negative, notes: nothing on the type and screen, all negative; Computerised tomogram: (May2022) was clean, notes: and in May had CAT scan and was clean; (unspecified date) there was a funny spot on caller's lung, notes: Did other tests and said after CAT scan of lungs, said there was a funny spot on caller's lung; Radiotherapy: (unspecified date) Unknown result; SARS-CoV-2 test: (28Jul2022) Positive, notes: Caller, female, aged 78, tested positive for Covid on 28Jul2022 on a home test. Therapeutic measures were taken as a result of vaccination failure, covid-19 which included Paxlovid Date and Time of Start of Drug: 29Jul2022, Date and Time of Last Administration: 30Jul2022  Clinical Information: It was reported that, patient experienced first symptoms when she got up to go get ready for bed, when she felt hot, head started hurting a little bit, wasn't coughing. Then took Covid test at midnight on Thursday night and was positive for Covid. Called doctor next morning at 11:30AM and had a tele-med visit and that's when caller was put on Paxlovid. Second question hematologist asked, was has caller had the Covid vaccine. Hematologist said from the last year, caller's type and screen from Dec2020, and type and screen done in Dec2021, did caller have any health issues what so ever, caller said no pretty healthy other than cancer diagnosis, caller didn't have anything. Only thing caller had done was that caller had the 2 Covid shots, didn't have 3rd dose at that time until spring. Physician said that is interesting. Caller didn't have a reaction to any of the shots, or anything, then HCP told caller that as a hematologist department starting to find more people having strange things happening in blood. Has seen an increase in people getting blood clots. Initially when people get the Covid shots, seeing uptick in blood clots 6-8 weeks after getting the shot, caller read that in the paper. HCP said no one is talking about people like caller who come back like a year later and have strange antibodies and antigens in blood, does not make any sense and cannot find any government data on this.