Initial information received on 20-Jul-2018 regarding an unsolicited valid serious case received from a consumer/non-HCP. This case involves an adult male patient who experienced ataxia and anxiety, while he received vaccine IMOVAX RABIES. The patient's past medical treatment(s), vaccination(s) and family history were not provided. It was reported several years before the bite he had fallen and shattered the same wrist that was bitten and had to have surgery with plates placed. At the time of the bite he was bleeding badly and the girl couldn't control the dog which they never found for a clear diagnosis. On an unknown date, the patient received a dose of suspect RABIES (HDC) VACCINE lot L1355-1 via unknown route in unknown administration site and 2 other doses were administered on unknown dates for suspect RABIES (HDC) VACCINE. The patient developed a serious significant balance issue, balance is terrible and he falls everyday, two weeks following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious walking issues, can barely walk now, two weeks following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious muscle weakness, two weeks following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious ataxia, following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious anxiety, following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious tremors in hands and arms, shake back and forth (diagnosed with essential tremor), following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. The patient developed a serious speech is affected and was not able to sleep, following the administration of RABIES (HDC) VACCINE. This event was assessed as medically significant. (Other relevant tests included They have done genetic and mutations testing that were all normal, heavy metal testing was negative, MRIs of cerebellum is normal, neck and spine x-rayed but no issues, tested for ALS and Parkinsons all negative). Final diagnosis was anxiety and ataxia. Patient received antianxiety drug. The patient outcome is reported as Unknown for significant balance issue, balance is terrible and he falls everyday, as Unknown for walking issues, can barely walk now, as Unknown for muscle weakness, as Unknown for ataxia, as Unknown for anxiety, as Unknown for tremors in hands and arms, shake back and forth that were diagnosed as essential tremors and as Unknown for speech is affected. Sender's Comments: This case involves an adult male patient who presented with ataxia (significant balance issue, walking issues, muscle weakness, essential tremors in hands and arms, shake back and forth and speech is affected) and anxiety post vaccination with IMOVAX RABIES. Time to onset is compatible. Genetic and mutations testing, MRI of cerebellum, neck and spine x-ray were normal and, tests for ALS and Parkinsons are negative. Additional information including patients medical history, family history, medical condition at the time of vaccination, and complete neurological evaluation results are needed for complete assessment of the case.