Since a few days after the shot, I have not had any breathing issues (can breathe deeply without catching my breath/without shortness of breath/without coughing).; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 49 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), intramuscular, administered in arm left, administration date 01Apr2021 14:45 (Lot number: EP6955) at the age of 49 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Asthma" (unspecified if ongoing); "sarcoidosis" (unspecified if ongoing). Concomitant medication(s) included: WELLBUTRIN; METOPROLOL TARTRATE; ALBUTEROL HFA; BREO ELLIPTA. Vaccination history included: Bnt162b2 (DOSE 1, lot number: EL3247, lot unknown: False, administration time: 01:15 PM, Vaccine location: Left arm.), administration date: 11Mar2021, for COVID-19 immunization. The following information was reported: THERAPEUTIC RESPONSE UNEXPECTED (non-serious) with onset 04Apr2021 12:00, outcome "unknown", described as "Since a few days after the shot, I have not had any breathing issues (can breathe deeply without catching my breath/without shortness of breath/without coughing).". Therapeutic measures were not taken as a result of therapeutic response unexpected.  Additional information: Facility where the most recent COVID-19 vaccine was administered to the patient was Workplace clinic. The patient did not received any other vaccines within 4 weeks prior to the COVID vaccine. medications the patient received within 2 weeks of vaccination: Wellbutrin, Metoprolol, Albuterol, Breo Ellipta. The patient was not previously diagnosed with COVID. The patient had not received any treatment for the adverse event. The patient was not diagnosed with COVID-19 prior to vaccination. The patient had not been tested for COVID-19 since the vaccination. The patient had no allergies to medications, food, or other products. The patient reported that this was a positive adverse event. Prior to the 2nd shot patient was using albuterol rescue inhaler daily and sometimes >1 time per day, and when she would breathe deeply, she would have some shortness of breath/coughing. Since a few days after the shot, she have not had any breathing issues (can breathe deeply without catching my breath/without shortness of breath/without coughing). she have not had to use the albuterol rescue inhaler since a few days after the 2nd shot. Breathing / lung function has greatly improved. On 08Apr2021, the patient realized that her breathing was more regular than it has been. At one point when she took a very deep breath, she realized that she could breathe freely and deeply, and that she did not wheeze or cough or get a shortness of breath feeling after taking a deep breath. she have asthma and sarcoidosis, so sometimes when she take a deep breath, she would cough or wheeze and have a feeling of shortness of breath, and she need to use her Albuterol rescue inhaler sometimes. Upon thinking about her breathing further, she realized that she did not use her Albuterol rescue inhaler at all during the work-week (Monday through Thursday). In fact, she realized that the last time she could recall using the inhaler was during the weekend, on Sunday 04Apr2021. Prior to getting my 2nd vaccine shot, I was using the rescue inhaler at least one time every day, and sometimes more than once a day. she realized on Thursday 08-April, that she had not used the inhaler for 4 days (Monday through Thursday), and she realized that the last time she used it was Sunday 04Apr2021. So, the date that she became aware that she was experiencing this, was Thursday 08-April. Once she noticed it, she thought about it further, and then she realized that the last time she had to use her inhaler, was Sunday 04Apr2021. So, she thought that the true awareness date was 04Apr2021.  No follow-up attempts are possible. No further information is expected.