She keeps losing more and more weight; Petite mal seizures/frequency of seizures increased; Grand mal convulsion/ One clonic tonic or grand mal seizure; This is a spontaneous report from a contactable Nurse (patient). A 70-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 administered in Arm Left on 19Feb2021 08:45 (Lot Number: EN6198) as 2ND DOSE, SINGLE for covid-19 immunisation. Medical history included epilepsy (diagnosed since age 6), guillain-barre syndrome (she cannot get the flu vaccine anymore because of her history of with Guillain-Barre Syndrome), she had COVID-19 in AUG2020 and has been having increased seizures since then as well, Seizures. She was positive on her COVID test, she forgets what was that it said when it came back, it didn't say positive, it said something else, she went back and forth after that first COVID test. She says it said detected, it didn't say anything else. She says after that she came home and self quarantined for 14 days, then went back for piece of mind to get a negative test, but they said positive, so then she quarantined 21 days that time. She says she went back and they tested her with the gold test which takes longer to her understanding to study that, and that came back negative. She says after 21 days she built up enough antibodies for it to be negative. She clarifies that she had COVID and COVID testing done before getting the doses of the Pfizer COVID-19 vaccine, before she got her her vaccinations. She had no other vaccinations on the dates she got her Pfizer COVID-19 vaccine doses or in the four weeks prior.  She uses Lysol wipes and Clorox to clean her house and her door knobs. She says she uses hand sanitizer and wears 1-2 masks. She says in 1990 she had an airborne virus that put her in intensive care for 21 days and she was paralyzed, so she is thankful to be alive, and that she is no longer paralyzed. She says this came along, and it brought back a lot of horrible memories. Caller says she had to live with something, and her mask, and a lot of handwashing. Call handler attempted to clarify this statement with the caller. Concomitant medications included clobazam (Manufacturer: Microlabs. NDC: 4271-315-01, EXP: 09Aug2021) 10mg tablets, two twice a day  taken for seizure; levetiracetam (LEVETIRACETAM 1A FARMA) 500mg, four tablets in the morning and four at night, taken for seizure.  The patient previously received first doe of bnt162b2 administered in Arm Left on 22Jan2021 08:45AM (Lot Number: EL3249) for covid-19 immunisation . The patient would like to know if the COVID-19 infection increases seizure activity. She has a history of epilepsy and has received both dose of her vaccine. She states that she petite mal seizures and has One clonic tonic or grand mal seizure on 2APR2021 at 12:35AM. She also reports that she keeps losing more and more weight and does not know why. She states that in JUL2020 she was 196 pounds and today she weighs 177 pounds. About frequency of seizures increased, the patient says that her seizures had been pretty well been controlled, for 6 months. She says that there were a couple times she had months seizure free, but now can't get through the day without multiple seizures. She says they are petit mal, but she is also having grand mal seizures. She clarifies that her seizures increased last July, after she got out of rehab, they got worse during the month of August. She confirms that she was diagnosed with COVID-19 in August 2020. She clarifies her seizures increased before she got the doses of the vaccine this year. She says she had convulsions on 2Apr2021, a grand mal seizure, at 12:35 in the morning. She was just wondering if there was any connection between COVID-19 and increased seizure activity. She says her neurologist and she are both hitting their heads on the floor and trying to think of what combination of meds could stop her seizures and convulsions to get her down to where she is not having multiple petit mal every day. She says she used to see her neurologist every 2-3 months, now she sees him every month. She says every 2-3 months he changes her medication. She says he has her on two drugs now, and he increased them both, they are hoping to get answers, if her seizures have not calmed down and gone away he is going to take her off Keppra. She is taking the Keppra generic, named Levetiracetam, she takes 500mg, four tablets in the morning and four at night. She says the other anti seizure medication is Clobazam, she takes two pills a day. She says each time he puts her on a different drug it is another chemical change to her body and another expense to be constantly changing drugs. She says her neurologist might change her medications again when she goes back May 20th for her follow up. She says there could be drug interactions and stuff that her neurologist might not be aware of, she is not having a fun time. She says her neurologist tried to put her on two different drugs to good take care of the problem, one was Keppra and her insurance denied that one so he said let's try this one and put it thru her insurance for authorization and it was accepted but they said they don't carry it and get her private pharmacist. The outcome of Petite mal seizures and Grand mal seizure was not recovered, of other event was unknown.