Swollen wrists; Sensation of throat closing/tightened throat; Itchiness all over the body; Hives covering entire body (raised welts and red  dots in some places like hands and neck); immune reaction to the booster dose; red dots in various places on the body; swollen eyes and lips; swollen eyes and lips; This spontaneous case was reported by a consumer and describes the occurrence of ERYTHEMA (red dots in various places on the body), LIP SWELLING (swollen eyes and lips), EYE SWELLING (swollen eyes and lips), JOINT SWELLING (Swollen wrists) and THROAT TIGHTNESS (Sensation of throat closing/tightened throat) in a 19-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 068H21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Previously administered products included for an unreported indication: JANSSEN COVID-19 VACCINE (J and J vaccine) on 07-Apr-2021. Concurrent medical conditions included Asthma since 01-Jan-2005, Hypersensitivity reaction, Hives, Latex allergy (reaction : hives and swollen lipes/eyes) since 06-Jan-2008 and Migraine (Migraines) since 01-Jan-2013. Concomitant products included FLUTICASONE PROPIONATE (FLOVENT) from January 2008 to an unknown date, MONTELUKAST SODIUM (SINGULAIR) from January 2018 to an unknown date, TOPIRAMATE from January 2014 to an unknown date, ETHINYLESTRADIOL, NORETHISTERONE (ALYACEN) from January 2020 to an unknown date and FOLIC ACID from 01-Jan-2020 to an unknown date for an unknown indication.    On 06-Jan-2022 at 5:30 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 07-Jan-2022, the patient experienced ERYTHEMA (red dots in various places on the body), LIP SWELLING (swollen eyes and lips), EYE SWELLING (swollen eyes and lips), THROAT TIGHTNESS (Sensation of throat closing/tightened throat), PRURITUS (Itchiness all over the body), URTICARIA (Hives covering entire body (raised welts and red  dots in some places like hands and neck)) and IMMUNISATION REACTION (immune reaction to the booster dose). On 08-Jan-2022, the patient experienced JOINT SWELLING (Swollen wrists). The patient was treated with LEVOCETIRIZINE DIHYDROCHLORIDE (ALLEGRA [LEVOCETIRIZINE DIHYDROCHLORIDE]) ongoing from 07-Jan-2022 for Adverse event, at a dose of 180 milligram twice a day; PREDNISONE for Adverse event, at a dose of 20 milligram once a day and VITAMIN D NOS ongoing since an unknown date for Adverse event, at an unspecified dose and frequency. At the time of the report, ERYTHEMA (red dots in various places on the body), LIP SWELLING (swollen eyes and lips), EYE SWELLING (swollen eyes and lips), JOINT SWELLING (Swollen wrists), THROAT TIGHTNESS (Sensation of throat closing/tightened throat), PRURITUS (Itchiness all over the body), URTICARIA (Hives covering entire body (raised welts and red  dots in some places like hands and neck)) and IMMUNISATION REACTION (immune reaction to the booster dose) had not resolved.            The patient received the Moderna booster dose on 06-Jan-2022. Within 16 hours from taking the Moderna shot, the patient's entire body was covered in hives and throat felt tight but did not have any trouble breathing.  The urgent care assessed it likely as a latex allergic reaction from the band aid that the pharmacy used after they administered the shot. The patient was prescribed prednisone but was asked not to use it until Sunday till 09-Jan-2022, as it would affect the effectiveness of the shot. Urgent care asked the patient to use Benadryl for the hives.  The hives subsided during the day (itchy skin remained) but then started to return around 9 P.M. On 08-Jan-2022, the patient woke up to worse hives, including swollen eyes, lips, and wrists. The patient called the allergist who said that it was not a latex allergy but an immune reaction to the booster dose. The allergist asked the patient to take the Prednisone immediately and take Allegra 180 mg/twice daily.  The hives had subsdided somewhat, but were still present for the patient every morning when the patient woke up. The allergist said that it could take a few weeks for the hives to disappear.   Most recent FOLLOW-UP information incorporated above includes: On 15-Jan-2022: Follow received on 15-Jan-2022 contain significant information- Reporter added , Medical history of patient updated, Events added and patient demographics updated On 16-Jan-2022: Follow-up information received on 16-Jan-2022 contains non significant information