back to having blood in her stools/ still bleeding/ numerous large volume stools; she did not have blood on the toilet paper, any rectal bleeding/ had no bleeding or anything for the rest on the day on 29Mar2021; This is spontaneous report from a contactable consumer (patient). A 77-year-old female patient received bnt162b2 (BNT162B2), dose 2 via an unspecified route of administration at the age of 77-years-old, administered in Arm Left on 28Mar2021 (Lot Number: ER2613) as single dose for COVID-19 immunization. Medical history included ongoing irritable bowel syndrome for a good part of her life, over 50 years, High level of hormones, Testosterone (Problems for the last couple of years, 2-3 years), Losing hair, Rectal bleeding from Jan2021 to an unknown date (Rectal bleeding, noticed blood on toilet paper, and rectal bleeding, in the beginning of Jan2021), that her stools were thin and maroon color/that her stools had specks in them, clots, that looked like blood. She started complaining about this. Concomitant medication included spironolactone taken as Diuretic or for Hormones from Jan2021 and ongoing. The patient previously received bnt162b2 (BNT162B2), dose 1 via an unspecified route of administration at the age of 77-years-old, administered in Arm Left on 28Feb2021 (Lot Number: EL9267) as single dose for COVID-19 immunization and experienced bleeding, blood in her stools, she did not have blood on the toilet paper, any rectal bleeding and she had volumes of regular stool like normal people stool. She stated she had no bleeding or anything for the rest on the day, aching arm, and Volumes of regular stool/ went to the bathroom 20 times. The patient has had Irritable Bowel Syndrome for a good part of her life, over 50 years, and since the pandemic and being house bound the Irritable Bowel Syndrome was worse. She wanted to get the vaccines but wanted to address the bleeding first that started in Jan2021 the day she started her spironolactone medication. She stated her and her husband wanted to get the vaccines but it was so hard to get in. Her doctor suspects Hemorrhoids. She believed it is not Hemorrhoids because she doesn't hurt or itch. She believes she has blockages in her bowels. That her stools were thin and maroon color. That her stools had specks in them, clots, that looked like blood. She started complaining about this, and noticed blood on toilet paper, and rectal bleeding, in the beginning of Jan2021. Then they were finally able to get their vaccines. The day after receiving the vaccine, 29Mar2021, she did not have blood on the toilet paper, any rectal bleeding, and she had volumes of regular stool, like normal people stool. She had numerous large volume stools on 30Mar2021. She stated she had no bleeding or anything for the rest on the day on 29Mar2021. She told her husband and sister. She thinks there may be something in the vaccine that could help her Irritable Bowel Syndrome. She wanted to report her experience in case it could help someone and help down the road for Irritable Bowel Syndrome patients. On 30Mar2021 she was back to having blood in her stools. She stated she is still bleeding in Mar2021. The side effects said some may have diarrhea but not her. She was scheduled to have a blood test in the next 2 weeks to check her hormone levels and see if the medication was helping her. The patient underwent lab tests and procedures which included colonoscopy: results not reported on 27Apr2020, computerised tomogram: results not reported on 27Apr2020. Numerous large volume stools resolved on 30Mar2021. Outcome of the rest of the events was unknown.