rash; couldn't move her arm at all,could only move her biceps and triceps, but not her rotator cuff nor her deltoid, no movement on her shoulder; Arthritis on her left wrist and Raynaud Syndrome got worse; Arthritis on her left wrist and Raynaud Syndrome got worse; pain as soon as the needle went in, pain went down her left arm; fever; This spontaneous case was reported by a consumer and describes the occurrence of VACCINATION SITE MOVEMENT IMPAIRMENT (couldn't move her arm at all,could only move her biceps and triceps, but not her rotator cuff nor her deltoid, no movement on her shoulder), ARTHRITIS (Arthritis on her left wrist and Raynaud Syndrome got worse), RAYNAUD'S PHENOMENON (Arthritis on her left wrist and Raynaud Syndrome got worse), VACCINATION SITE PAIN (pain as soon as the needle went in, pain went down her left arm) and RASH (rash) in a 61-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 057M21A, 016C21A, 004C21A and 031B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Sulfonamide allergy (Sulfa allergy), Arthritis (on her left wrist) and Raynaud's syndrome.   On 07-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 05-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 22-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 20-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 20-Apr-2022, the patient experienced ARTHRITIS (Arthritis on her left wrist and Raynaud Syndrome got worse), RAYNAUD'S PHENOMENON (Arthritis on her left wrist and Raynaud Syndrome got worse), VACCINATION SITE PAIN (pain as soon as the needle went in, pain went down her left arm) and PYREXIA (fever). On 21-Apr-2022, the patient experienced VACCINATION SITE MOVEMENT IMPAIRMENT (couldn't move her arm at all,could only move her biceps and triceps, but not her rotator cuff nor her deltoid, no movement on her shoulder). On 22-Apr-2022, the patient experienced RASH (rash). The patient was treated with TRAZODONE at a dose of Only as needed. In April 2022, RASH (rash) had resolved. On 23-Apr-2022, PYREXIA (fever) had resolved. At the time of the report, VACCINATION SITE MOVEMENT IMPAIRMENT (couldn't move her arm at all,could only move her biceps and triceps, but not her rotator cuff nor her deltoid, no movement on her shoulder), ARTHRITIS (Arthritis on her left wrist and Raynaud Syndrome got worse), RAYNAUD'S PHENOMENON (Arthritis on her left wrist and Raynaud Syndrome got worse) and VACCINATION SITE PAIN (pain as soon as the needle went in, pain went down her left arm) had not resolved.            No concomitant medications were reported. After 2nd Booster dose on Wednesday 20-Apr-2022 on left arm and states that the patient felt pain as soon as the needle went in and then the pain went down left arm. The patient said this type of pain was unusual because it never happened with the other doses. The pain got worse as the day progressed and then the patient had a fever. On Thursday and Friday, the patient couldn't move arm at all, still had pain and a fever. The patient started presenting a rash that same Friday. On Saturday, the fever broke and the rash started diminishing, the patient was still in a lot of pain, but recovered some movement on arm; the patient could only move biceps and triceps, but not rotator cuff nor deltoid (clarified this meant no movement on shoulder). From that day on, The patient kept on having a lot of pain and limited movement in shoulder. The patient been using heat and having massages but nothing helps. The patient mentioned having Arthritis on left wrist and Raynaud Syndrome, and that both have gotten worse since the second Booster dose. Company comment:This spontaneous case concerns an 61-year-old female patient with underlying medical history of Arthritis and Raynaud's phenomenon who experienced the unexpected, non-serious AESI of Arthritis aggravated. The event occurred the same day after receiving a dose of mRNA1273 as fourth dose of COVID-19 vaccine. Patient had arthritis of left wrist, which was reported to have gotten worse since administration of the vaccine.  The treatment details were not stated in the case. The patient's underlying medical history of Arthritis may be contributory factor for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-550368, MOD-2022-550322, MOD-2022-550346 (Patient Link).; Sender's Comments: This spontaneous case concerns an 61-year-old female patient with underlying medical history of Arthritis and Raynaud's phenomenon who experienced the unexpected, non-serious AESI of Arthritis aggravated. The event occurred the same day after receiving a dose of mRNA1273 as fourth dose of COVID-19 vaccine. Patient had arthritis of left wrist, which was reported to have gotten worse since administration of the vaccine.  The treatment details were not stated in the case. The patient's underlying medical history of Arthritis may be contributory factor for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.