Stroke; throwing up bright orange bile; left side was paralyzed; Left side being numb; felt sick; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 74-year-old female patient received BNT162b2 (BNT162B2), on 12May2022 as dose 4 (booster), single (Lot number: FM9992) at the age of 74 years, in left arm for COVID-19 immunization. The patient's relevant medical history was not reported. There were no concomitant medications. Vaccination history included: BNT162b2 (Dose 1, date: 13Mar2021, LOT: EN6204), administration date: 13Mar2021, when the patient was 73-year-old, for COVID-19 immunization; BNT162b2 (Dose 2, date: 06Apr2021 (Could possibly be 06Nov2021, but cant tell from the writing. April would make sense though.), LOT: EN6207), administration date: 06Apr2021, when the patient was 73-year-old, for COVID-19 immunization; BNT162b2 (Dose 3, date: 09Oct2021, LOT: 301308), administration date: 09Oct2021, when the patient was 73-year-old, for COVID-19 immunization. The following information was reported: ILLNESS (non-serious) with onset 13May2022, outcome "unknown", described as "felt sick"; HYPOAESTHESIA (non-serious) with onset 14May2022, outcome "unknown", described as "Left side being numb"; PARALYSIS (Medically significant) with onset 14May2022, outcome "unknown", described as "left side was paralyzed"; VOMITING (hospitalization) with onset 14May2022, outcome "recovered" (14May2022), described as "throwing up bright orange bile"; CEREBROVASCULAR ACCIDENT (hospitalization) with onset 17May2022, outcome "recovering", described as "Stroke". The patient was hospitalized for cerebrovascular accident (start date: 17May2022, discharge date: 23May2022, hospitalization duration: 6 day(s)); for vomiting (hospitalization duration: 6 day(s)). The events "stroke", "throwing up bright orange bile", "left side was paralyzed", "felt sick" and "left side being numb" required physician office visit and emergency room visit. Therapeutic measures were taken as a result of paralysis, hypoaesthesia.  Clinical course: Prior Vaccinations, list any other vaccinations within four weeks prior to the first administration date of the suspect vaccine was none. AE(s) following prior vaccinations was none. Patient's Medical History (including any illness at time of vaccination) was none. Family Medical History Relevant to AE(s) was not provided. 12May2022 caller received 4th COvid-19 vaccine. After, she started throwing up bright orange bile and went to hospital. Hospital was more worried about orange bile, but she also had a stroke on her brain stem. There was a clot of the end of brain stem. Happened right after she took the shot. Took the three other vaccines and never had this problem. Doesn't know if it was a bad dose or what. After the fourth shot, she wound up in the hospital having a stroke. Bile was worse on the 14May2022, so she called the ambulance to take her to the hospital. She couldn't walk that day. She threw up a lot at one time. Threw up once at home and once on the ambulance. Left side being numb all over started on 14May2022. Whole left side was paralyzed. Still goes to therapy. Left side is not back all the way yet. She was in rehab at (withheld). Will continue with rehab outpatient. Stroke wasn't diagnosed until the 17May2022 when went to Dr. (name withheld) for an appointment. The numbness was present on the 14-16 of May 2022, but when she went to the emergency department, they said she was just vomiting and sent her home. When she went for her appointment with (withheld), he saw her and got upset that she wasn't checked at hospital. The stroke was on the right side which caused drooping on the left side. (withheld) had her admitted. He had to call the hospital because she wouldn't go back to the emergency department. The hospital didn't do anything for her on the 14May2022 and 15May2022. So, she waited for doctors appointment on the 17May2022. Clarified that she felt sick on the 13May2022 but wasn't vomiting yet. She went to the hospital on the 14May2022. The orange bile was what got her. That never happened before. Brain got fried, so she's not 100% on dates. She was probably admitted at the hospital until 23May2022. Then, she was discharged to (withheld) rehab. Discharged from (withheld) on the 28May2022. Want to send her back to rehab because she is not 100% there yet. Clarified patient is referring to completing outpatient rehab. Will continue outpatient rehab to finish learning how to walk. She is improving, but she is not 100% yet. The rehab is helping her walk again. She can't walk without a walker yet, but she is better than she was when she went into the hospital. Patient was hospitalized approximately, 6 days in the hospital and 5 days in (withheld).