after second shot of vaccination patient felt absolutely horrible. On 30Mar2021, patient immediately started vaginal bleeding heavily for 7 to 9 days; migraine; after second shot of vaccination patient felt absolutely horrible. On 30Mar2021, patient immediately started vaginal bleeding heavily for 7 to 9 days; Severe body pain especially the left arm where I received shot; Severe body pain especially the left arm where I received shot; Was sick and down for 7 to 9 days.; Could not communicate to anyone that I felt like I had to go to emergency room.; Because I could not wake up and could not even speak when I did wake up briefly just to go to urinate.; Cannot think straight at all.; My memory is horrible. I forget things even minutes after they happen or I say or I heard.; severe debilitating depression; Personality changes either daily or weekly; This is a spontaneous report from a contactable consumer (Patient). A non-pregnant female patient of unspecified age received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Solution for injection; Lot number: ER8730) via an unspecified route of administration in left arm on 30Mar2021 as single dose for COVID-19 immunization. Facility where the most recent COVID-19 vaccine administered was Pharmacy or Drug Store. Medical history of the patient included PTSD (Post-traumatic stress disorder), ADHD (Attention deficit hyperactivity disorder), depression, severe anxiety, our age negative, had scarlet fever at age 13, 3 DNC spontaneous abortions, C-section and asthma. Patient has allergy to cantaloupe. Patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Concomitant medications or any other medications the patient received within 2 weeks of vaccination included 3 prescriptions that patient take daily (unspecified). Prior to vaccination, the patient was not diagnosed with COVID-19 and since the vaccination, the patient had not been tested for COVID-19. Patient previously took amoxicillin and morphine for unspecified indications and experienced allergy. Patient previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Solution for injection; Lot number: EN6202) via an unspecified route of administration in left arm on an unspecified date as single dose for COVID-19 immunization and had flu for 2 to 3 days. On 30Mar2021, a few hours after second shot of vaccination patient felt absolutely horrible and experienced vaginal bleeding for 7 to 9 days then every other week sometimes just a few days a part 2 to 3 days heavy to light, migraines, severe body pains especially in the left arm where patient was administered vaccination shot, patient was sick and down for 7 to 9 days, could not communicate to anyone that she felt like she had to go to emergency room because she could not wake up and could not even speak when she did wake up briefly just to go to urinate, cannot think straight, memory was horrible, forget things even minutes after they happen or she said or heard, this happened even while driving. Four weeks maybe only six days of severe debilitating depression for no reason almost committed herself to hospital due to the severity of it. When patient was going to get herself checked she could not even get a hold of her therapist or psychologist due to it being a holiday. Personality changes either daily or weekly. The events resulted in healthcare professional office/clinic visit [Life threatening illness (immediate risk of death from the event), Disability or permanent damage]. Reporter considered the events as serious. Therapeutic measures taken in response to the events included therapy and possible change in medication. Outcome of the events were not recovered.