rash in chest; weakness; soreness in injection arm; pain in her both shoulders; pain in all her bones; headache; rash is located on her upper chest, lower neck area/rash, like bumps, 6 to 8 inches in a circular shape; discomfort; This case was reported by a consumer via call center representative and described the occurrence of allergic reaction in a 66-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included aneurysm cerebral and aneurysm repair (the patient would to have aneurysm clipped, which was previously scheduled some time ago in August or September.). Concurrent medical conditions included headache.   On 30th April 2019, the patient received the 1st dose of Shingrix. On an unknown date, less than a month after receiving Shingrix, the patient experienced allergic reaction, weakness of arms, pain in arm, shoulder pain, bone pain, headache aggravated, red rash and discomfort. On an unknown date, the outcome of the allergic reaction, weakness of arms, pain in arm, shoulder pain, bone pain, headache aggravated, red rash and discomfort were unknown.   It was unknown if the reporter considered the allergic reaction, weakness of arms, pain in arm, shoulder pain, bone pain, headache aggravated, red rash and discomfort to be related to Shingrix.  Additional case details were provided as follows: The patient had no previous allergies to any medications, foods,etc. The patient got the live virus vaccine and had no problem at all The patient received the dose of Shingrix and experienced weakness and soreness in her arm and severe pain in all of her bones, including both her shoulders in the first week.  On the day of reporting, the patient had trouble lifting a milk jug due to the weakness and soreness and still has in her arm.  The patient also experienced headaches for 2 days during the second week after injection.  The patient had never reacted to any injection her whole life (especially this strongly) and no one told her she could also get a rash.  The patient developed light pink rash, like bumps, 6 to 8 inches in a circular shape the second week and it still remained after one week. The patient has not treated it with anything. The patient had rash which was located on her upper chest, lower neck area and does not itch. The patient would see her physician about it but her physician suspects she was having a mild allergic reaction to Shingrix and asked the patient to go into the office for a visit. The caller felt strongly that Shingrix was too potent or too strong for the average person based on the fact she has never had this strong of a reaction to any other vaccine in her lifetime.  The patient would discuss with her doctor whether or not to get the second vaccine and if so, when, because she was not sure she wants to go through these symptoms again.  She stated that if she does have it, she may choose to have it after she has aneurisym surgery. The patient knows she would feel bad and have headaches after the surgery and so she does not want to take the second injection during that timeframe and make things worse. The patient may consider of getting the second vaccine after 8 to 9 months when she would be fully recovered from the surgery.   The caller also mentioned that she wished there was a titer for shingrix. The patient has been given the consent for the follow up.