itching/experiencing itching on her neck /then itching in her hands first in one hand and then in her other hand, also in her thighs and tummy; scratching there were red bumps and dark; rashes; This spontaneous case was reported by a patient and describes the occurrence of PRURITUS (itching/experiencing itching on her neck /then itching in her hands first in one hand and then in her other hand, also in her thighs and tummy), ERYTHEMA (scratching there were red bumps and dark) and RASH (rashes) in a 40-year-old female patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. 030g22b) for COVID-19 prophylaxis.     Previously administered products included for COVID-19 prophylaxis: Moderna COVID-19 Vaccine (1st dose, lot #037k20a) on 28-Dec-2020, Moderna COVID-19 Vaccine (2nd dose, lot #043l20a) on 26-Jan-2021, Moderna COVID-19 Vaccine (1st booster and lot #031h21a) on 27-Dec-2021; for Product used for unknown indication: Flu vaccine. Past adverse reactions to the above products included No adverse event with Flu vaccine, Moderna COVID-19 Vaccine, Moderna COVID-19 Vaccine and Moderna COVID-19 Vaccine. Concomitant products included INFLUENZA VACCINE for an unknown indication.    On 18-Nov-2022, the patient received fourth dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. In November 2022, the patient experienced PRURITUS (itching/experiencing itching on her neck /then itching in her hands first in one hand and then in her other hand, also in her thighs and tummy) and ERYTHEMA (scratching there were red bumps and dark). November 2022, the patient experienced RASH (rashes). The patient was treated with HYDROCORTISONE for Itching and Erythema, at an unspecified dose and frequency and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Itching and Erythema, at a dose of UNK (Pill). At the time of the report, PRURITUS (itching/experiencing itching on her neck /then itching in her hands first in one hand and then in her other hand, also in her thighs and tummy) and RASH (rashes) had not resolved and ERYTHEMA (scratching there were red bumps and dark) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In August 2022, SARS-CoV-2 test: Positive.     For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Unknown), the reporter did not provide any causality assessments.   Patient received other vaccines in the 4 weeks prior to COVID-19 vaccine. Patient never had issues with the vaccination or like, and not had any allergies to anything. Patient started getting rashes like five days after got the vaccination. It's almost close to month. Patient still have itching. Following vaccination around 5 to 7 days after receiving the second booster dose patient started experiencing itching on her neck and after scratching there were red bumps and dark, then itching in hands first in one hand and then in other hand, also in thighs and tummy. The symptoms are ongoing itching. Patient treated with antihistamine