Postmenopausal Menstruation, bleeding and cramping; Small lump in the inner thigh; inappropriate schedule of vaccine administered; Extreme premenstrual syndrome in breast and under armpits and under lymph nodes; Passing small blood clots; started having periodic premenstrual symptoms, like cramps; This is a spontaneous report from a contactable consumer (patient). A 58-year-old female patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: EW0151), via an unspecified route of administration on 07Apr2021 as a single dose for COVID-19 immunization. The patient's medical history included cysts (fibrocystic cysts in her breast and a baker's cyst behind the knee many years ago), Ovarian surgery, blood pressure and blood potassium. The patient's concomitant medications were not reported. The patient stated that she read an article online about the women who took the Pfizer vaccine should report if they were having menstrual issues. She stated that she took her first dose of the Pfizer vaccine on 13Apr2021, and on 12May2021 she started having periodic premenstrual symptoms, like cramps. She stated that she has her regular menstrual cycle now, and she had cancelled her second dose. Because of her side effects she put off her 3 week booster shot that was scheduled for 28Apr2021 at 1400. She did not show up and was waiting to hear from a couple physicians regarding a lump on her inner right thigh that was moving around. She had trouble finding it the next day. She checked the other side to see if it had to do with fat composition or whatnot. It disappeared and she did follow up with her primary physician on it.  Her primary physician said that if it had been a blood clot, she would have felt pain, but was not sure about that. Patient stated that she has not been able to find the lump. The patient's physician said that the patient could reschedule the vaccination as she could have it within 42 days. The patient stated that about a week and a half ago, she experienced extreme premenstrual syndrome in her breast and under her armpits and under her lymph nodes, cramping on monday and tuesday and some time yesterday, and the last 2 days she has been passing small blood clots like menstrual. The patient stated that the PMS has subsided somewhat. The patient has been taking ibuprofen. She has not had PMS or a period for at least 5 years. Last night, the patient stated that she was on the internet reading articles regarding the Covid vaccination and menstruation issues, and it is being reported but not fully. The patient described as: it seems like they were trying to keep it hush. The patient had side effects so bad over the weekend, the past weekend. The patient scheduled an appointment with a gynecologist whom she will visit in the middle of June because of these symptoms. The patient stated that she was afraid that she will get a mammogram and was not sure what's going on. Patient described that it was a kind of weird. The patient noticed the lump around approximately 24Apr2021 or 25Apr2021. It would have been between 2 and 3 weeks after the first shot, not even 3 weeks. The patient stated that she visited her physician in the first week of May and told her physician that she was having trouble finding it, then she felt it and didn't feel it again. It made her very queasy the first time she felt it. The patient stated that she had cysts in the past. She had fibrocystic cysts in her breast and a baker's cyst behind the knee many years ago. The patient stated that the cysts felt weird like soft and were moving around. It made her queasy. The patient stated that she has had the premenstrual syndrome in her breast and under her armpits and under her lymph nodes for at least a week. She used to get this during her monthly cycle during that time, she forgot what they call is severe PMS. The patient stated that she was going through very severe PMS just like that up until 2015. There was a year she had an ovarian mass removed and her fallopian tubes. She only has one ovary left. Once her period went away it went away. She never suffered, maybe slight PMS until she was fully into menopause. It has been this last week. She couldn't get out of bed because she had cramping and was in pain. She never used to cramp except in high school. The patient sated that she doesnt really feel lumps in her lymph nodes, it is just very tender and her nipples were highly sensitive. Underneath and along her rib cage and under her armpits is very warm to the touch. It is like a very bad premenstrual syndrome. It is definitely not warm or hot anymore, it has gotten better. The swelling has gone down, and she last noticed any blood clotting last evening and the clots were tinier like little dots. The blood clots started on monday 17May2021. The patient had cramps when she was in bed in the morning, then after she took pain medicine it subsided. The patient stated that she had no cramping today. The first time she had cramping was Monday 17Apr2021. The last time she had cramps was yesterday. The worst was on tuesday on 18May2021. Tuesday night was the worst for the blood clots too. She doesn't know. She hadn't had them for 5 years then it came upon recently. She doesn't know if she has recovered completely. She doesn't know if the cramps or the blood clots will return. If it goes like a normal cycle like before pre-menopause it will go away and then come back the next month. The patient stated that after she urinated today, she did not see any blood, and she was not using a pad. The blood clots have pretty much cleared up. The patient stated that she was reading and looking on the internet at ingredients and it was so scary and she was really scared. Patient stated that it was 42 days since her first dose. It would have been 42 days yesterday within the time limit to have the second shot of the booster. Now it is the forty third day and she has not had it. She was reading that it can be given 90 to 120 days. She is getting mixed messages. The people she lives with are high risk, and that's the only reason she got it. The case was assessed as serious. The patient stated that she was taking Ibuprofen and her symptoms subsided somewhat. Treatment was taken for events. The outcome of the events was resolved for cramps and resolving for other events.   Information for lot number has been requested.