exocrin pancreatic insufficiency; nearly total loss of production of pancreatic enzymes by my pancreas; daily frequent loose & oily bowel movements; This is a spontaneous report from a contactable consumer (patient).  A 74-years-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE), dose 1 via an unspecified route of administration, administered in Arm Left on 28Feb2021 03:15 (Batch/Lot Number: EN-6198) age at vaccination of 74-years-old, as single dose, dose 2 via an unspecified route of administration, administered in Arm Left on 21Mar2021 04:15 (Batch/Lot Number: EN-6208) age at vaccination of 74-years-old, as single dose for covid-19 immunisation; paclitaxel albumin (ABRAXANE), via an unspecified route of administration from 20Oct2020 (Batch/Lot number was not reported) to 02Feb2021, at unspecified dose for an unspecified indication; atezolizumab (TECENTRIQ), via an unspecified route of administration from 20Oct2020 (Batch/Lot number was not reported) to 02Feb2021, at unspecified dose for an unspecified indication.  Medical history included metastatic breast cancer (tnbc) from an unknown date and unknown if ongoing. The patient was not pregnant and was not pregnant at the time of vaccination. Concomitant medications included paroxetine (PAROXETINE) taken for an unspecified indication, start and stop date were not reported; atenolol (ATENOLOL) taken for an unspecified indication, start and stop date were not reported; atorvastatin calcium (LIPITOR ORIFARM) taken for an unspecified indication, start and stop date were not reported; apixaban (ELIQUIS) taken for an unspecified indication, start and stop date were not reported; amlodipine (AMLODIPINE) taken for an unspecified indication, start and stop date were not reported. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine.  The patient experienced exocrin pancreatic insufficiency on an unspecified date, daily frequent loose & oily bowel movements on 02Mar2021 and nearly total loss of production of pancreatic enzymes  on an unspecified date.  Doctor or other healthcare professional office/clinic visit was required. Facility where the most recent COVID-19 vaccine was administered: Pharmacy or Drug Store. Approximately two days after the first Pfizer shot the patient experienced daily frequent loose & oily bowel movements which was unsure of the cause. The patient initially thought it might be due to chemo (Abraxane) & immunotherapy (Tecentriq) that patient had been from 20Oct2020 to 02Feb2021. The patient subsequently went to her oncologist who thought it could be IBS but eventually saw gastroenterologist on 05May2021 who suspected "Exocrin pancreatic insufficiency or "epi".  The patient had a stool analysis which confirmed the nearly total loss of production of pancreatic enzymes by pancreas. The patient was put on CREON medication by gastroenterologist that must take with every meal or snack she eat and likely she will be on for the rest of her life. Prior to vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient has not been tested for COVID-19. The action taken in response to the events for paclitaxel albumin was post-therapy, for atezolizumab was post-therapy.  Outcome of the events was unknown.  The patient doesn't not know if this problem is due to cancer treatment or the Pfizer vaccine.   No follow-up attempts are needed. No further information is expected