1 day after vaccination, left upper arm began with 2-3 mm raised pustule appearing rash. Then to R arm, then throughout abdomen, lower extremities, back. Rash continues with intermittent eruptions,; very intensely itchy.; Moderna - 21Nov2021; Pfizer - 29Sep2022; This is a spontaneous report received from a contactable reporter(s) (Nurse). The reporter is the patient.  A 42-year-old female patient (not pregnant) received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 29Sep2022 at 15:15 as dose 4 (booster), single (Lot number: RA2089) at the age of 42 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Asthma" (unspecified if ongoing), notes: Other medical history: Asthma. Concomitant medication(s) included: ESCITALOPRAM; VITAMIN D NOS; B COMPLEX [VITAMIN B COMPLEX]. Past drug history included: Compazine, reaction(s): "Dystonic Reaction", notes: Known allergies: Compazine and Reglan with Dystonic Reaction. Morphine with hives; Reglan, reaction(s): "Dystonic Reaction", notes: Known allergies: Compazine and Reglan with Dystonic Reaction. Morphine with hives; Morphine, reaction(s): "hives", notes: Known allergies: Compazine and Reglan with Dystonic Reaction. Morphine with hives. Vaccination history included: moderna coviD-19 vaccine (Dose 3, single), administration date: 21Nov2021, when the patient was 41-year-old, for COVID-19 Immunization; Moderna covid-19 vaccine (Dose1, single, (lot number= 026L20A, Left Arm)), for Covid-19 immunization; Moderna covid-19 vaccine (Dose 2, single, (lot number= 004M20A, Left Arm)), for COVID-19 Immunization. The following information was reported: INTERCHANGE OF VACCINE PRODUCTS (non-serious) with onset 29Sep2022, outcome "unknown", described as "Moderna - 21Nov2021; Pfizer - 29Sep2022"; RASH (non-serious) with onset 30Sep2022, outcome "not recovered", described as "1 day after vaccination, left upper arm began with 2-3 mm raised pustule appearing rash. Then to R arm, then throughout abdomen, lower extremities, back. Rash continues with intermittent eruptions,"; PRURITUS (non-serious) with onset 30Sep2022, outcome "not recovered", described as "very intensely itchy.". The events "1 day after vaccination, left upper arm began with 2-3 mm raised pustule appearing rash. then to r arm, then throughout abdomen, lower extremities, back. rash continues with intermittent eruptions," and "very intensely itchy." required physician office visit. Therapeutic measures were taken as a result of rash, pruritus.  Additional information: Patient received other vaccine in four weeks. Patient did not received other vaccine 4weeks product. Patient received other medications in two weeks was Escitalopram 2.5 mg, Vitamin D 2000 units, B Compl. If Covid prior vaccination was Yes. If Covid tested post vaccination was No. The other vaccine same date product: Moderna dose number= 1 and 2, vaccine date= 29Sep2022. Prev dose administration date= 21Nov2021. Prev dose dose number= 3. Prev dose vaccine location= Left Arm. Previous dose lot number= 903904. Facility type Vaccine: Pharmacy or Drug Store. 1 day after vaccination, left upper arm began with 2-3 mm raised pustule appearing rash. Then to R arm, then throughout abdomen, lower extremities, back. Rash continues with intermittent eruptions, very intensely itchy. The patient received treatment with Prednisone, Benadryl, Zyrtec. The patient did not tested Covid tested post vaccination.  No follow-up attempts are needed. No further information is expected.