heart attack; in coma; fell over on the floor while eating dinner; This spontaneous case was reported by a patient and describes the occurrence of MYOCARDIAL INFARCTION (heart attack), COMA (in coma) and FALL (fell over on the floor while eating dinner) in a 68-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Diabetes. Concomitant products included METFORMIN for Diabetes, PAROXETINE HYDROCHLORIDE (PAXIL [PAROXETINE HYDROCHLORIDE]) and OXYCODONE HYDROCHLORIDE, PARACETAMOL (PERCOCET [OXYCODONE HYDROCHLORIDE;PARACETAMOL]) for an unknown indication.    On 09-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Oct-2021, the patient experienced MYOCARDIAL INFARCTION (heart attack) (seriousness criteria hospitalization prolonged, medically significant and life threatening), COMA (in coma) (seriousness criteria hospitalization prolonged, medically significant and life threatening) and FALL (fell over on the floor while eating dinner) (seriousness criterion hospitalization prolonged). The patient was hospitalized from 24-Oct-2021 to 10-Dec-2021 due to COMA, FALL and MYOCARDIAL INFARCTION. At the time of the report, MYOCARDIAL INFARCTION (heart attack), COMA (in coma) and FALL (fell over on the floor while eating dinner) had resolved.        mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was withdrawn on an unknown date.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Other concomitant medications included other unspecified medications. The patient could not get second dose as she was in coma. Her doctor wanted her to start the vaccine all over again. She restarted vaccine from 16-Dec-2021. She had a heart attack on 24-Oct-2021. On that day she was in her neighbour's house, fell over on the floor while eating dinner, and was taken to hospital. She was revived seven times and was in a coma. They put some tubing in her stomach, then was transferred to re-habitation, where she regained talking, and eating, and was discharged on 10-Dec-2021. She never had a heart problem before this incident.  Company comment: This case concerns a 68-year-old female patient with medical history of diabetes who experienced heart attack, coma and fall two months and 16 days following the first dose of mRNA-1273 vaccine. The patient was hospitalized, and events were reported as resolved. The patient's underlying history of diabetes remains a major confounding factor in addition to concomitantly administered paroxetine an oxycodone. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-448101 (Patient Link).; Sender's Comments: This case concerns a 68-year-old female patient with medical history of diabetes who experienced heart attack, coma and fall two months and 16 days following the first dose of mRNA-1273 vaccine. The patient was hospitalized, and events were reported as resolved. The patient's underlying history of diabetes remains a major confounding factor in addition to concomitantly administered paroxetine an oxycodone. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.