itchy; arm is swollen; eyes are so blurry which impeded her ability to work; Legs and calves are killing her; throbbing pain in back; still exhausted; a lot of pressure; sudden pain in her chest; everything hurts/achy/sore; dizzy; blurry eyes/can barely see their computer; fever dropped to 100.1°F; sweating a lot/they were like in a puddle of water; body aches; chills; nausea; 103.5°F fever, 105-degree feve; sudden pain in their heart/heart hurt so bad/not like chest pain,but like a stabbing pain in the heart that lasted for 36 hours; like a spasm in their heart; This spontaneous case was reported by a consumer and describes the occurrence of ANGINA PECTORIS (sudden pain in their heart/heart hurt so bad/not like chest pain,but like a stabbing pain in the heart that lasted for 36 hours) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 035C21A and 027O21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 14-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 10-Sep-2021 at 10:30 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 10-Sep-2021, the patient experienced ANGINA PECTORIS (sudden pain in their heart/heart hurt so bad/not like chest pain,but like a stabbing pain in the heart that lasted for 36 hours) (seriousness criterion medically significant) and CARDIOSPASM (like a spasm in their heart). On 11-Sep-2021, the patient experienced HYPERHIDROSIS (sweating a lot/they were like in a puddle of water), MYALGIA (body aches), CHILLS (chills), NAUSEA (nausea) and PYREXIA (103.5°F fever, 105-degree feve). On 12-Sep-2021, the patient experienced PYREXIA (fever dropped to 100.1°F). On 13-Sep-2021, the patient experienced DIZZINESS (dizzy), VISION BLURRED (blurry eyes/can barely see their computer) and PAIN (everything hurts/achy/sore). On an unknown date, the patient experienced PRURITUS (itchy), PERIPHERAL SWELLING (arm is swollen), IMPAIRED WORK ABILITY (eyes are so blurry which impeded her ability to work), PAIN IN EXTREMITY (Legs and calves are killing her), BACK PAIN (throbbing pain in back), FATIGUE (still exhausted), DISCOMFORT (a lot of pressure) and CHEST PAIN (sudden pain in her chest). The patient was treated with FAMOTIDINE (PEPCID [FAMOTIDINE]) for Adverse event, at an unspecified dose and frequency and IBUPROFEN for Adverse event, at an unspecified dose and frequency. On 10-Sep-2021, ANGINA PECTORIS (sudden pain in their heart/heart hurt so bad/not like chest pain,but like a stabbing pain in the heart that lasted for 36 hours) and CARDIOSPASM (like a spasm in their heart) had resolved. On 12-Sep-2021, PYREXIA (fever dropped to 100.1°F) had resolved. At the time of the report, DIZZINESS (dizzy), VISION BLURRED (blurry eyes/can barely see their computer), HYPERHIDROSIS (sweating a lot/they were like in a puddle of water), PAIN (everything hurts/achy/sore), PRURITUS (itchy), PERIPHERAL SWELLING (arm is swollen), IMPAIRED WORK ABILITY (eyes are so blurry which impeded her ability to work), PAIN IN EXTREMITY (Legs and calves are killing her), BACK PAIN (throbbing pain in back), FATIGUE (still exhausted), DISCOMFORT (a lot of pressure) and CHEST PAIN (sudden pain in her chest) outcome was unknown and MYALGIA (body aches), CHILLS (chills), NAUSEA (nausea) and PYREXIA (103.5°F fever, 105-degree feve) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 11-Sep-2021, Body temperature: 103.5 f (High) 103.5 F fever around 1 am. On 12-Sep-2021, Body temperature: 100.1 f (High) fever dropped to 100.1°F.         No relevant concomitant medications were reported  Company comment: This case concerns a 60 year old female patient, who experienced unexpected serious events of ANGINA PECTORIS.  The serious event occurred same day after the second dose of mRNA-1273 vaccine.  The patient also experienced non-serious events of  CARDIOSPASM, HYPERHIDROSIS, MYALGIA, CHILLS, NAUSEA, PYREXIA, DIZZINESS, VISION BLURRED, PAIN, PRURITUS, PERIPHERAL SWELLING, IMPAIRED WORK ABILITY, PAIN IN EXTREMITY, BACK PAIN, FATIGUE, DISCOMFORT, CHEST PAIN, ANGINA PECTORIS. The non-serious events occurred on 1-3 days after the second dose of mRNA-1273 vaccine. Limited information regarding the events have been provided at this time.  The benefit-risk relationship of the vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 13-Sep-2021: FU received and contains new events: Peripheral swelling, Impaired work ability, Pain in extremity, Back pain, Fatigue, Discomfort, Chest Pain.; Sender's Comments: This case concerns a 60 year old female patient, who experienced unexpected serious events of ANGINA PECTORIS.  The serious event occurred same day after the second dose of mRNA-1273 vaccine.  The patient also experienced non-serious events of  CARDIOSPASM, HYPERHIDROSIS, MYALGIA, CHILLS, NAUSEA, PYREXIA, DIZZINESS, VISION BLURRED, PAIN, PRURITUS, PERIPHERAL SWELLING, IMPAIRED WORK ABILITY, PAIN IN EXTREMITY, BACK PAIN, FATIGUE, DISCOMFORT, CHEST PAIN, ANGINA PECTORIS. The non-serious events occurred on 1-3 days after the second dose of mRNA-1273 vaccine. Limited information regarding the events have been provided at this time.  The benefit-risk relationship of the vaccine is not affected by this report.