SARS-CoV-2 test positive; SARS-CoV-2 test positive; chronic deep itching; Extreme Facial swelling; eyelid swelling; lip & tongue swelling; lip & tongue swelling; facial rash; developed abdominal pain/bloating; developed abdominal pain/bloating; chronic fatigue; burning, rashes up to 75% body; burning, rashes up to 75% body; immune dysfunction; Weight gain; elevated liver enzymes; elevated Hg/Hct; elevated Hg/Hct; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 19 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 26Apr2021 09:45 (Lot number: EW0172) at the age of 19 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "eczema" (unspecified if ongoing); "allergies" (unspecified if ongoing); "Known allergies: mold" (unspecified if ongoing); "Known allergies: pets" (unspecified if ongoing). The patient did not received any other vaccine within four weeks and COVID prior to vaccination was unknown. Concomitant medication(s) included: ZYRTEC [CETIRIZINE HYDROCHLORIDE]. Past drug history included: Amoxicillin, reaction(s): "Known allergies: amoxicillin"; Zithromax, reaction(s): "Known allergies: Zithromax". Vaccination history included: Bnt162b2 (Dose 1, lot number: EW0150,, administration time: 02:00 PM, anatomical location: Left arm), administration date: 05Apr2021, when the patient was 19 years old, for Covid-19 immunization.  The following information was reported: VACCINATION FAILURE (medically significant), COVID-19 (medically significant) all with onset 27Dec2021, outcome "unknown" and all described as "SARS-CoV-2 test positive"; PRURITUS (disability) with onset 07May2021 12:00, outcome "not recovered", described as "chronic deep itching"; SWELLING FACE (disability) with onset 07May2021 12:00, outcome "not recovered", described as "Extreme Facial swelling"; SWELLING OF EYELID (disability) with onset 07May2021 12:00, outcome "not recovered", described as "eyelid swelling"; LIP SWELLING (disability), SWOLLEN TONGUE (disability) all with onset 07May2021 12:00, outcome "not recovered" and all described as "lip & tongue swelling"; RASH (disability) with onset 07May2021 12:00, outcome "not recovered", described as "facial rash"; ABDOMINAL DISTENSION (disability), ABDOMINAL PAIN (disability) all with onset 07May2021 12:00, outcome "not recovered" and all described as "developed abdominal pain/bloating"; FATIGUE (disability) with onset 07May2021 12:00, outcome "not recovered", described as "chronic fatigue"; SKIN BURNING SENSATION (disability), RASH (disability) all with onset 07May2021 12:00, outcome "not recovered" and all described as "burning, rashes up to 75% body"; IMMUNE SYSTEM DISORDER (disability) with onset 07May2021 12:00, outcome "not recovered", described as "immune dysfunction"; WEIGHT INCREASED (disability) with onset 07May2021 12:00, outcome "not recovered", described as "Weight gain"; HEPATIC ENZYME INCREASED (non-serious) with onset 07May2021 12:00, outcome "not recovered", described as "elevated liver enzymes"; HAEMATOCRIT INCREASED (non-serious), HAEMOGLOBIN INCREASED (non-serious) all with onset 07May2021 12:00, outcome "not recovered" and all described as "elevated Hg/Hct". Symptoms started 9 days post vaccine. The events "chronic deep itching", "extreme facial swelling", "eyelid swelling", "lip & tongue swelling", "lip & tongue swelling", "facial rash", "developed abdominal pain/bloating", "developed abdominal pain/bloating", "chronic fatigue", "burning, rashes up to 75% body", "burning, rashes up to 75% body", "immune dysfunction", "weight gain", "elevated liver enzymes", "elevated hg/hct" and "elevated hg/hct" were evaluated at the physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: blood test: (unspecified date) ana detected; haematocrit: (unspecified date) elevated hg/hct; haemoglobin: (unspecified date) elevated hg/hct; hepatic enzyme abnormal: (unspecified date) elevated liver enzymes; investigation: (unspecified date) anticardiolipid elevated; sars-cov-2 test: (27Dec2021) positive; weight: (07May2021) gain. Rheumatology, allergy/immunology, dermatology consulted but no definitive diagnosis. Therapeutic measures were taken as a result of pruritus, swelling face, swelling of eyelid, lip swelling, swollen tongue, rash, abdominal distension, abdominal pain, fatigue, skin burning sensation, rash, immune system disorder, weight increased, hepatic enzyme increased, haematocrit increased, haemoglobin increased and included treated with steroids (Extreme Facial swelling, eyelid swelling, lip & tongue swelling, facial rash), prescription medication, allergy testing, U/S.  No follow-up attempts are possible. No further information is expected.