a really bad headache, later diagnosed as a migraine by her neurologist, which has been continuous 24 hours 7 days; couldn't speak in clear sentences / couldn't talk /conversation is hard for her and can't last very long; brain fog; lost motor skills; hard to walk; had a couple of weeks where she couldn't get out of bed due to bad brain fog and fatigue; extreme light and noise sensitivity; extreme light and noise sensitivity; body aches / a pain of 8/10 /pain never fully goes away; chills /body chills that lasted 2 days; fever; headaches /have a headache that would last half a day; gets tired of thinking too much / Fatigue; This spontaneous case was reported by a consumer and describes the occurrence of MIGRAINE (a really bad headache, later diagnosed as a migraine by her neurologist, which has been continuous 24 hours 7 days) in a 36-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 039A21A and 027A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was reported by the reporter.  Concomitant products included BOTULINUM TOXIN TYPE A (BOTOX), ERENUMAB (AIMOVIG [ERENUMAB]), NAPROXEN SODIUM (ALEVE), ACETAMINOPHEN, ACETYLSALICYLIC ACID, CAFFEINE, PARACETAMOL (EXCEDRINIL), TOPIRAMATE, BUTALBITAL, CAFFEINE, PARACETAMOL (BUTALBITAL, ACETAMINOPHEN & CAFFEINE), AMITRIPTYLINE and PROPRANOLOL HYDROCHLORIDE (PROPRANOLOL [PROPRANOLOL HYDROCHLORIDE]) for an unknown indication.   On 08-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 07-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced MIGRAINE (a really bad headache, later diagnosed as a migraine by her neurologist, which has been continuous 24 hours 7 days) (seriousness criterion hospitalization), SPEECH DISORDER (couldn't speak in clear sentences / couldn't talk /conversation is hard for her and can't last very long), FEELING ABNORMAL (brain fog), MOTOR DYSFUNCTION (lost motor skills), GAIT DISTURBANCE (hard to walk), VACCINATION COMPLICATION (had a couple of weeks where she couldn't get out of bed due to bad brain fog and fatigue), HYPERACUSIS (extreme light and noise sensitivity), PHOTOPHOBIA (extreme light and noise sensitivity), MYALGIA (body aches / a pain of 8/10 /pain never fully goes away), CHILLS (chills /body chills that lasted 2 days), PYREXIA (fever), HEADACHE (headaches /have a headache that would last half a day) and FATIGUE (gets tired of thinking too much / Fatigue). The patient was hospitalized for 3 days due to MIGRAINE. The patient was treated with SUMATRIPTAN SUCCINATE (SUMATRIPTAN [SUMATRIPTAN SUCCINATE]) ongoing since an unknown date for Pain, at an unspecified dose and frequency. At the time of the report, MIGRAINE (a really bad headache, later diagnosed as a migraine by her neurologist, which has been continuous 24 hours 7 days), SPEECH DISORDER (couldn't speak in clear sentences / couldn't talk /conversation is hard for her and can't last very long), FEELING ABNORMAL (brain fog), MOTOR DYSFUNCTION (lost motor skills), GAIT DISTURBANCE (hard to walk), VACCINATION COMPLICATION (had a couple of weeks where she couldn't get out of bed due to bad brain fog and fatigue), HYPERACUSIS (extreme light and noise sensitivity), PHOTOPHOBIA (extreme light and noise sensitivity), MYALGIA (body aches / a pain of 8/10 /pain never fully goes away), CHILLS (chills /body chills that lasted 2 days), PYREXIA (fever), HEADACHE (headaches /have a headache that would last half a day) and FATIGUE (gets tired of thinking too much / Fatigue) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medications included hiropractic and beta blockers and non drug treatment included acupuncture, massage therapy.   Lab data includes CT scans and blood test.  Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded. However, the medical history of polypharmacy factor could be a contributory factor.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded. However, the medical history of polypharmacy factor could be a contributory factor.