Has had zero herpes outbreaks since receiving Covid-19 vaccine; This is a spontaneous report from a Pfizer sponsored program. A contactable 64-years-old female patient reported that she received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, lot number was not reported, patient was 64-years old at the time of vaccination), via an unspecified route of administration in Arm Left on 22Mar2021, and received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, lot number was not reported, patient was 64-years old at the time of vaccination), via an unspecified route of administration in Arm Left on 13Apr2021 as a single diose for COVID-19 immun-ization. Reported that patient taking COVID-19 vaccine because I care about other people. The pa-tient's medical history included she was diagnosed with herpes simplex virus 2 when she was 25 years old which was ongoing, and as she gets older, the outbreaks of herpes increase. The patient's concom-itant medication(s) included acyclovir [aciclovir] (ACYCLOVIR [ACICLOVIR, 400 mg], manufacturer Zy-dus) taken for Suppress herpes outbreaks from an unspecified start date and ongoing, reported that patient has been on Acyclovir since she was in her early 30's. Acyclovir had basically stopped working, reported that when she first began using Acyclovir, she would have 3-4 breakouts per year. Reported that her one leg is an inch and a half longer than the other, so her height depends on which leg she stands on, she generally tells people 5'7". On an unspecified date in Mar2021, the patient experienced has had zero herpes outbreaks since receiving covid-19 vaccine. Reporter seriousness for Has had zero herpes outbreaks since receiving Covid-19 vaccine was unspecified. Reported that patient received both doses of the Pfizer Covid-19 vaccine, at first she thought that she was just imagining things, so patient was looking at (website name) to see if there was a herpes message board, place where peo-ple can say this happened to me and others can comment, reported that she made a post on (website name) about how she has not had any outbreaks of herpes since receiving the Covid-19 vaccine and on 09Jun2021, she had a comment where someone else said that happened to them as well, she had not able to provide details for the other patient who has had no herpes outbreaks following the Covid-19 vaccine, she thinks that it is a global messaging board and that the posts are anonymous. Patient want that someone at Pfizer needs to know about patients not experiencing outbreaks of herpes fol-lowing the Covid-19 vaccine to have it looked into because there is no cure for herpes simplex 2, Covid-19 vaccine may not be curing herpes simplex 2, but may permanently suppress it as long as you are vaccinated. Reported that as she has gotten older, the frequency of herpes outbreaks has in-creased. So she thought that it could have been due to her living in Florida and spending so much time in the sun as the sun can trigger outbreaks, she moved back to TN almost 2 years ago in August and she is not hardly out in the sun at all. Outbreaks were just getting to be almost constant, the outbreak would peel and then boom, another outbreak. It was to the point where she was going to call her doc-tor to switch her medication to something else that would suppress the outbreaks. reported that after she received the Covid-19 vaccine, she went to a trip in the southwest where she was in the sun a lot, even more than when she lived in Florida. And she experienced no outbreaks of herpes while on the trip, which was at the end of Apr2021, early May2021. Caller reported that she didn't change anything and kept taking the Acyclovir the way it was prescribed. Reported that her appointment was at 09:00 or 09:30, but she doesn't believe that she received the vaccine until 10:30 due to the line. Patient had not received additional Vaccines Administered on Same Date of the Pfizer Suspect, no AE required emergency Room and physician Office visit. Patient had not received prior Vaccinations (within 4 weeks). The outcome of event was not recovered. Family Medical History Relevant included there is heavy heart disease on her dad's side and heavy cancer on her mom's side., she means by heavy is there were 9 kids in each case, all of them on the one side died of heart disease and all of them on the other side died of cancer except for one.  information about lot/batch number has been requested.