This case was reported by a consumer via call center representative and described the occurrence of pruritus in a 63-year-old female patient who received SHINGRIX for prophylaxis. In October 2018, the patient received the 1st dose of SHINGRIX. In October 2018, less than a month after receiving SHINGRIX, the patient experienced pruritus, eye pruritus, red rash, eye red, fever, nausea, influenza-like symptoms, sleepiness, numbness of upper extremities, tingling of extremity and adverse event. On an unknown date, the patient experienced inflammation, eye inflammation and general body pain. The patient was treated with BENADRYL and Vitamin D. On an unknown date, the outcome of the pruritus, eye pruritus, red rash, eye red, inflammation and eye inflammation were not recovered/not resolved and the outcome of the fever, nausea, influenza-like symptoms, sleepiness, numbness of upper extremities and tingling of extremity were recovered/resolved and the outcome of the general body pain was recovering/resolving and the outcome of the adverse event was unknown. It was unknown if the reporter considered the pruritus, eye pruritus, red rash, eye red, inflammation, eye inflammation, fever, nausea, influenza-like symptoms, sleepiness, numbness of upper extremities, tingling of extremity, general body pain and adverse event to be related to SHINGRIX. Additional information was reported as follows: The patient was under a lot of stress, prior to vaccination with SHINGRIX. In October 2018, at least two weeks before the date of reporting, the patient was vaccinated with the SHINGRIX. The patient initially experienced fever, nausea and flu-like symptoms and slept a lot the first 2 to 3 days. On the day following of vaccination, the patient's arm was numb and tingly, it took an hour for her to get it to move again. The patient stated that she had a reaction to shingles shot. She experienced every symptom that she had read about the vaccine online, however the patient experienced one specific symptom that she had not read about in any of the research. Every day, usually three to four times a day, the patient started with itching in an area which would last for 15 to 30 minutes or sometimes even longer before stopping, where the itching was very intense, which turned bright red and inflamed leading next to many bumps, which goes away after a few hours and then re-starts at another area. The patient experienced this in her eyes, arm, back, waist, feet, thigh as well as at her bra area and waist area. The patient explained that it seems to like a parasite which jumped from one area to another. At the time of reporting, the patient was still experiencing problems with itching and rash. The patient also experienced pain in her right side like she was being jabbed. The pain used to stay for a while before going away again. At the time of reporting, the patient still had pain which occurred twice a day. The patient thought she was getting better. A day before the date of reporting, the patient had broken out twice. On the date of reporting, the patient had itching but didn't break out into rash. The patient had been taking Vitamin D and BENADRYL to help with the itching. The patient enquired how long these symptoms would last.