Hands had a tactical sensation that was strange, they were not alright; balance was off. Then it went away, until 22Oct2021 when woke up in the morning and was out of balance/ few more episodes of lost of balance/ It's like legs are not holding up straight; This spontaneous case was reported by a physician and describes the occurrence of BALANCE DISORDER (balance was off. Then it went away, until 22Oct2021 when woke up in the morning and was out of balance/ few more episodes of lost of balance/ It's like legs are not holding up straight) and PARAESTHESIA (Hands had a tactical sensation that was strange, they were not alright) in a 76-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 053E21A, 011A21A and 047A21A) for COVID-19 vaccination.     Concurrent medical conditions included Pain. Concomitant products included BENZALKONIUM CHLORIDE, SODIUM CHLORIDE (ALIVE) for Pain, ATORVASTATIN, ACETYLSALICYLIC ACID (BABY ASPIRIN), RAMIPRIL, OXCARBAZEPINE (TRILEPTAL), METOPROLOL, UBIDECARENONE (COQ10 [UBIDECARENONE]), CHONDROITIN SULFATE, GLUCOSAMINE HYDROCHLORIDE (OSTEO BI-FLEX [CHONDROITIN SULFATE;GLUCOSAMINE HYDROCHLORIDE]), CHONDROITIN SULFATE, GLUCOSAMINE SULFATE, METHYLSULFONYLMETHANE (TRIPLE FLEX [CHONDROITIN SULFATE;GLUCOSAMINE SULFATE;METHYLSULFONYLMETHANE]), VITAMIN C [ASCORBIC ACID], CENTRUM SILVER ADULTS 50+ and FLAXSEED OIL [LINUM USITATISSIMUM SEED OIL] for an unknown indication.   On 24-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 25-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Aug-2021, the patient experienced BALANCE DISORDER (balance was off. Then it went away, until 22Oct2021 when woke up in the morning and was out of balance/ few more episodes of lost of balance/ It's like legs are not holding up straight). On 21-Oct-2021, the patient experienced PARAESTHESIA (Hands had a tactical sensation that was strange, they were not alright). At the time of the report, BALANCE DISORDER (balance was off. Then it went away, until 22Oct2021 when woke up in the morning and was out of balance/ few more episodes of lost of balance/ It's like legs are not holding up straight) and PARAESTHESIA (Hands had a tactical sensation that was strange, they were not alright) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Company Comment -This case concerns a 76-year-old male patient with medical history of pain and on (ramipril, metoprolol, glucosamine sulfate,  for unknown indication) who experienced the unexpected event of balance disorder.  The events occurred 4 months 24 days after the second the first dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was unknown as there was no details about the first dose.  The reporter did not provide the causality assessment with product use. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.  Patient stated that I ended up in the ER and was admitted in the hospital. I was dismissed on 23Oct2021 and had a few more episodes of lost of balance. On 24Oct2021 I had them again and on 25Oct2021 again  Patient stated that he was been checked for a presumed autoimmune disease.  Concomitant medications included Calcium with Vitamin D, Magnesium and copper with dose 630mg.  Patient was treated with Steroids. Patient mentioned to have had an ablation treatment in the heart on 19-Oct-   This case was linked to MOD-2021-363477, MOD-2021-363342 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 25-Oct-2021: Follow up received contains updated reporter occupation.; Sender's Comments: This case concerns a 76-year-old male patient with medical history of pain and on (ramipril, metoprolol, glucosamine sulfate,  for unknown indication) who experienced the unexpected event of balance disorder.  The events occurred 4 months 24 days after the second the first dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was unknown as there was no details about the first dose.  The reporter did not provide the causality assessment with product use. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.