Body turned Red, post Plavix and imaging dye, about 2 months after the 2nd shot; "Felt like I was in the middle of 1000 fire ants"   about 2 months after the 2nd shot post Plavix and imaging dye; Had a Heat Shock about 2 months after the 2nd shot post Plavix and imaging dye; Allergic reaction, post Plavix and imaging dye, about 2 months after the 2nd shot , Diagnosed with an Allergic Reaction; This spontaneous case was reported by a patient and describes the occurrence of ERYTHEMA (Body turned Red, post Plavix and imaging dye, about 2 months after the 2nd shot), FEELING ABNORMAL ("Felt like I was in the middle of 1000 fire ants"   about 2 months after the 2nd shot post Plavix and imaging dye), HEAT ILLNESS (Had a Heat Shock about 2 months after the 2nd shot post Plavix and imaging dye) and HYPERSENSITIVITY (Allergic reaction, post Plavix and imaging dye, about 2 months after the 2nd shot , Diagnosed with an Allergic Reaction) in a 52-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 017-E21A and 011D) for COVID-19 vaccination. Co-suspect product included non-company product CLOPIDOGREL BISULFATE (PLAVIX) for an unknown indication. No medical history was provided by the reporter.  Concurrent medical conditions included Kidney disorder (Kidney patient) since 2018. On 27-Jul-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Aug-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient started CLOPIDOGREL BISULFATE (PLAVIX) (unknown route) 1 dosage form. On 27-Nov-2021, the patient experienced ERYTHEMA (Body turned Red, post Plavix and imaging dye, about 2 months after the 2nd shot), FEELING ABNORMAL ("Felt like I was in the middle of 1000 fire ants"   about 2 months after the 2nd shot post Plavix and imaging dye), HEAT ILLNESS (Had a Heat Shock about 2 months after the 2nd shot post Plavix and imaging dye) and HYPERSENSITIVITY (Allergic reaction, post Plavix and imaging dye, about 2 months after the 2nd shot , Diagnosed with an Allergic Reaction). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Allergic reaction, at an unspecified dose and frequency. On 27-Nov-2021, ERYTHEMA (Body turned Red, post Plavix and imaging dye, about 2 months after the 2nd shot), FEELING ABNORMAL ("Felt like I was in the middle of 1000 fire ants"   about 2 months after the 2nd shot post Plavix and imaging dye), HEAT ILLNESS (Had a Heat Shock about 2 months after the 2nd shot post Plavix and imaging dye) and HYPERSENSITIVITY (Allergic reaction, post Plavix and imaging dye, about 2 months after the 2nd shot , Diagnosed with an Allergic Reaction) had resolved. It was reported that patient took 1st dose and did not have any reaction after 1st dose. No concomitant drug was reported. It was reported that patient received an imaging dye earlier on 27NOV2021 prior to walking in to the Dialysis center. after patient received  imaging  dye and Plavix earlier that day, while waiting in the dialysis facility, patient had an allergic reaction, patient was rushed to the ER. The open line was clotted, Body turned Red ,Felt like was in the middle of 1000 fire ants. patient had a Heat Shock. patient was rushed to the emergency room. He was diagnosed with an Allergic Reaction. It was also reported that patient never had allergic reactions in the past. patient did not receive any booster dose of Moderna or other brand COVID-19 vaccine.