FEELING HOT; LEGS ACHY; MUSCLE PAIN; FEELING FATIGUE/ EXTREMELY TIRED; LOWER BACK PAIN; DRY COUGH; LOSS FEELING IN EXTREMITIES/ LOOSE FEELING IN FINGER TIPS AND TOES/LOST FEELING IN PENIS; INSOMNIA/COULD NOT SLEEP; HALLUCINATION; CHEST PAIN ALMOST LIKE AN ULCER FEELING LOWER CHEST NEXT TO THE HEART; SHORTNESS OF BREATH; FEVER; SWEATS; CHILLS; FELT POUNDING HEADACHES; FEELING COLD; FELT DEHYDRATED; URINE DISCOLORATION; This spontaneous report received from a patient concerned a 23 year old male. The patient's height, and weight were not reported. The patient's past medical history included covid infection, lyme disease, and surgery of venous varicose, and other pre-existing medical conditions included the patient had no known drug allergies. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 202A21A, and batch number: 202A21A expiry: UNKNOWN) dose was not reported, administered on 09-APR-2021 13:15 in left arm for prophylactic vaccination. No concomitant medications were reported.  On 09-APR-2021 around 7 pm, the patient started feeling fatigue, lower back pain, muscles pain and his legs were so achy. Around 10 pm, he went to his girlfriend house and tried to lay down felt pounding headaches for 10 to 15 minutes and he was physically hot to touch. Then, He started to have chills and sweats. He was cold although he was wrapped in 2 blankets. He had severe chest pain almost like an ulcer feeling (lower chest next to the heart), shortness of breath and dry cough. He started to lose feeling in his fingertips and toes. He also lost feeling in his penis which he felt it when he couldn't go to the bathroom. He couldn't sleep and he started hallucinating. The Chest pain and the loss feeling in the extremities got better by 10-Apr-2021. On 12-APR-2021 he was feeling hot, sweating and fatigue, He felt better at night. Headaches, shortness breath, sweating and the occasional dry cough was still not resolved. he stated that he usually doesn't sweat that much. He didn't take any medications to treat the side effects but only Vitamin C and Vitamin D. He was thinking to going to emergency room but he slept and woke up better. He also felt dehydrated, the urine was discolored, and he thought it is because of all the sweating.  The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from hallucination, chest pain almost like an ulcer feeling lower chest next to the heart, insomnia/could not sleep, and muscle pain, lower back pain, and feeling fatigue/ extremely tired on 11-APR-2021, and loss feeling in extremities/ loose feeling in finger tips and toes/lost feeling in penis, chills, and fever on 10-APR-2021, was recovering from feeling hot, had not recovered from felt pounding headaches, shortness of breath, sweats, and dry cough, and the outcome of felt dehydrated, urine discoloration, legs achy and feeling cold was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0:20210431878-JANSSEN COVID-19 VACCINE Ad26.COV2.S-Hallucination. This event is considered unassessable. The event has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event.