LIVER DISORDER; PANCREAS DISORDER; SNEEZING; TICKLE; DAMAGED HEART/HEART FAILURE (SHORTNESS OF BREATH, COUGHING, ALMOST PASSED OUT, HARDLY WALK, PRODUCTIVE COUGH); HEADACHE; THIRSTY; This spontaneous report received from a patient concerned a 68 year old female. The patient's height, and weight were not reported. The patient's past medical history included breast cancer in 2007 and Covid infection started on 01-SEP-2020 which got recovered on an unspecified date in Dec -2020 and concurrent conditions included abstains from alcohol, and non-smoker. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number:- 180525, expiry: 25-DEC-2021) dose was not reported, administered on 10-MAR-2021 with frequency 1 total on right arm for prophylactic vaccination. No concomitant medications were reported.  On an unspecified date in 2021, laboratory data included: X-ray (NR: not provided) unknown. On 11-MAR-2021, the patient experienced coughing, thirsty, headache. On 12-MAR-2021, the patient experienced shortness of breath. It was reported that, the patient's breathing had been on and off and hence she thought that it might have been because of allergies, sneezing and coughing. She thought that she had COVID again and had made a physician visit who gave her the inhalers but she mentioned that the inhalers had not worked. On 01-APR-2021, the patient experienced as she could hardly walk due to shortness of breath and worse, worse and worse shortness of breath. The patient had visited the emergency department upon recommendation from the pharmacist on 13-APR-2021 where she was made to do certain tests. On 14-APR-2021, laboratory data included: blood test (NR: not provided) something was high. On 17-APR-2021, laboratory data included: sonogram (NR: not provided) unknown, and stress test (NR: not provided) heart failure. On 19-APR-2021, laboratory data included: brain natriuretic protein test BNP (NR: not provided) elevated, and computerized tomogram CT scan (NR: not provided) unknown. The patient also visited a lung specialist on 22-APR-2021 who told her that she had fluid on lungs caused by heart issues. On 28-APR-2021, laboratory data included: echocardiogram ECHO (NR: not provided) unknown. On 03-May-2021, the patient experienced extremely shortness of breath. On 04-MAY-2021, laboratory data included: echocardiogram ECHO (NR: not provided) Unknown. On 10-MAY-2021, laboratory data included: positron emission tomography PET scan (NR: not provided) unknown. On 11-MAY-2021, the patient experienced damaged heart/heart failure (shortness of breath, coughing, almost passed out, hardly walk, productive cough). On an unspecified date, the patient experienced liver disorder, pancreas disorder, sneezing, and tickle. Laboratory data (dates unspecified) included: COVID-19 virus test negative (NR: not provided) negative. Treatment medications (dates unspecified) included: Carvedilol, Spironolactone, Lisinopril used for damaged heart/ heart failure, Azithromycin used for coughing and Salbutamol sulfate used for shortness of breath. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from sneezing, and headache on 12-MAR-2021, had not recovered from damaged heart/heart failure (shortness of breath, coughing, almost passed out, hardly walk, productive cough), and thirsty, and the outcome of liver disorder, pancreas disorder and tickle was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: 20210607508- covid-19 vaccine ad26.cov2-Heart failure. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).