High blood pressure stayed for about 24 hours; Heart Rate went to 120; Nausea; Sweating; This is a spontaneous report received from a contactable reporter(s) (Other HCP). The reporter is the patient.  A 45-year-old female patient (not pregnant) received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 15Oct2022 at 16:30 as dose 4 (booster), single (Lot number: GJ3277) at the age of 45 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "PVC heart arrhythmia" (unspecified if ongoing); "Depression" (unspecified if ongoing); "Anxiety" (unspecified if ongoing); "Morbid obesity" (unspecified if ongoing); "Hyperlipidemia" (unspecified if ongoing); "Hypothyroidism" (unspecified if ongoing); "Poly cystic ovarian syndrome" (unspecified if ongoing); "Chronic pain" (unspecified if ongoing); "Insomnia" (unspecified if ongoing); "Penicillin allergy" (unspecified if ongoing), notes: Penicillin and sulfa antibiotics, artificial sweeteners allergy; "sulfa antibiotics allergy" (unspecified if ongoing), notes: Penicillin and sulfa antibiotics, artificial sweeteners allergy; "artificial sweeteners allergy" (unspecified if ongoing), notes: artificial sweeteners allergy; "COVID-19" (unspecified if ongoing), notes: prior to vaccination, unspecified date. Concomitant medication(s) included: FLU [INFLUENZA VACCINE] taken for immunisation, on 01Oct2022 as dose number unknown, single. Vaccination history included: BNT162b2 (Dose Number: 1, Batch/Lot No: EH9899, Location of injection: Arm Right), administration date: 18Dec2020, when the patient was 43-year-old, for COVID-19 Immunization; BNT162b2 (Dose Number: 2, Batch/Lot No: EH9899, Location of injection: Arm Left), administration date: 12Jan2021, when the patient was 43-year-old, for COVID-19 Immunization; BNT162b2 (Dose Number: 3, Batch/Lot No: FF2588, Location of injection: Arm Right), administration date: 12Oct2021, when the patient was 44-year-old, for COVID-19 Immunization. The following information was reported: HEART RATE INCREASED (non-serious) with onset 16Oct2022 at 18:00, outcome "recovered" (16Oct2022 at 19:00), described as "Heart Rate went to 120"; HYPERTENSION (non-serious) with onset 16Oct2022 at 18:00, outcome "recovered" (Oct2022), described as "High blood pressure stayed for about 24 hours"; NAUSEA (non-serious) with onset 16Oct2022 at 18:00, outcome "unknown"; HYPERHIDROSIS (non-serious) with onset 16Oct2022 at 18:00, outcome "unknown", described as "Sweating". The events "high blood pressure stayed for about 24 hours", "heart rate went to 120", "nausea" and "sweating" required physician office visit and emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of hypertension, heart rate increased, nausea, hyperhidrosis.  Additional Information: Since the vaccination, has the patient has not been tested for COVID-19. Next day, on 16Oct2022, while sitting listening to book, patient's heart rate went to 120 and stayed there with nausea and sweating. Called Withheld and went to ER. High heart rate stayed for about an hour, high blood pressure stayed for about 24 hours. Lab work, EKG, x-ray all normal. Events were reported non-serious, did not result in death, was not life-threatening, did not cause/prolong hospitalization, was not disabling/incapacitating nor resulted to congenital anomaly/birth defect.   No follow-up attempts are possible. No further information is expected.