he's losing thoughts/his eyes didn't focus/his eyes wouldn't engage on what was happening; unable to put words together; tired; confused; changes in his cognitive and mental status; changes in his cognitive and mental status; This is a spontaneous report from a contactable consumer (patient's wife). A 74-year-old male patient received bnt162b2 (BNT162B2), dose 2 via an unspecified route of administration, administered in arm right on an unspecified date (Lot Number: EN6205) as single dose for covid-19 immunisation. The patient's medical history included wears hearing aids, multiple myeloma prior vaccine, and had trouble word finding and hard sometimes to remember names before the vaccines. concomitant medications included a normal list of medications he was taking but, it was lengthy. The patient previously received first dose of bnt162b2 on an unspecified date for covid-19 immunisation and no adverse effect. He did well with both shots, no reactions. The reporter's husband received his second COVID Vaccine and she started seeing changes in his cognitive and mental status on an unspecified date of 2021. He's had issues off and on of really unclear thinking and this week (May2021) he's losing thoughts, and unable to put words together. Symptoms began in early April, he maybe had small incidents in March but nothing that was worrisome. On Saturday of this week (01May2021), the patient could not put words together to make a sentence, and he was very tired. He was still tired even though he slept 12 hours night and he was confused. On 01May2021 in the evening he was off, but was repeating himself, not everything was making sense, but was able to attend baptism of their great nephew. He always sleeps 12 hours at night, but then just sat on couch with eyes shut, his eyes didn't focus and he would respond to his name but his eyes wouldn't engage on what was happening. This went on through 03May2021 by 04May2021. On 04May2021, he was in his chair and could not put words together still. Monday (03May2021) they played "Shut the Box,"- he has a masters degree but was unable to add two numbers that make ten. On Wednesday 05May2021 he went to the emergency room (ER) and they did a brain scan (MRI), extensive bloodwork and a urinalysis, everything came back normal and no sign of TIA or stroke. He had been improving since Wednesday (05May2021) at around 4:30 PM, after leaving the hospital, he started being able to put words and thoughts together again. On Thursday (06May2021) he was able to play "Shut the Box." She was calling to see if there have been any reports of mental reactions after the vaccines such as memory issues, or cognitive issues. She stated the neurologist was unaware of any neurologic issues following the vaccine. She stated he had no side effects after the vaccine and that she only had mild side effects for one night and then they resolved. She mentioned that her husband also had cancer. Prior to the vaccine the patient was seeing a neurologist for multiple myeloma, that was unrelated to the vaccine. The patient had a discussion with doctor about having a hard time remembering names and words like he used to, his doctor told him that it was typical with aging this was in January or February. Recently, in one instance, the patient handed the caller a pen and paper and asked the caller to put the battery in it. The caller asked the patient which one would it go in and the patient said either one. The patient wears hearing aids, and had for a number of years. He put transmitters in his ear instead of the ear piece. These instances both happened in the earlier part of Apr2021. His issues were still ongoing but, improving. The outcome of events was recovering.