She started not feeling well/she is sick; congestion; cold like symptoms; lost her sense of taste; sore throat; This is a spontaneous report from a contactable consumer. A 36-years-old female patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: EP6955), via an unspecified route of administration on arm left on 18Mar2021 at 10:10 (at the age of 36-years-old) as dose 1, single for COVID-19 immunization at clinic. The patient's medical history included Autoimmune compromised since Sep2011 and ongoing, Immune compromised since Sep2020 and Splenectomy in Dec2012. Concomitant medications was none. Historical vaccine included meningococcal and flu vaccines on 17Feb2021. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient had no AEs following prior vaccinations. On 27Mar2021, the patient experienced sore throat, on 02Apr2021, the patient lost her sense of taste, on an unknown date the patient started not feeling well/she was sick, congestion and cold like symptoms. That morning when eating she noticed she had lost her sense of taste. She started not feeling well last weekend-experiencing sore throat and congestion, but due to the weather was unsure if it was due to allergies or covid. She was getting tested for Covid tomorrow, but wanted to know since she already received the first dose could she potentially get a false positive? If she does test positive what should she do? She was scheduled to receive next dose on 08Apr2021. She said that unfortunately she thought she was sick and lost her sense of taste today and was being tested for Covid tomorrow. She had her first Pfizer Covid-19 dose 18Mar2021 and was asking could that affect the result of the test. She has auto-immune disease and immune compromised. She had a little sore throat last weekend on Saturday that went away, and then earlier this week she was congested, but she thought it was allergies. Has not run a fever or had any other symptoms. Until today, when eating breakfast and she couldn't taste it. She was drinking sparkling water during the call and couldn't taste it. She hasn't lost her sense of smell. She was immune compromised and doesn't have a spleen. She was auto immune compromised. She said that she really wasn't doing well health wise. She had an Emergency Room visit 3 weeks ago and urgent care visit 2 weeks ago. She saw a Gastrointestinal specialist and is scheduled for an endoscopy with colonoscopy at the hospital. She also has gall stones and has a consult for that issue. She has had a lot happen recently. The consumer stated she got her 1st dose last 18Mar2021 and experienced loss of sense of taste, cold like symptoms, sore throat and congestion. She mentioned she will have her 2nd dose on 08Apr2021. She has Idiopathic thrombocytopenic purpura, and her hematologist told her that people with this could experience adverse reactions similar to having the Covid virus and it could trigger an auto immune reaction. The adverse event did not resulted in emergency room or physician office visit. The outcome of event was not recovered for lost her sense of taste and unknown for started not feeling well/she is sick, congestion and cold like symptoms and recovered from sore throat on an unspecified date in 2021.  Follow-up (02Apr2021): This is a follow-up spontaneous report from . New information included: The consumer stated she got her 1st dose last 18Mar2021 and experienced loss of sense of taste, cold like symptoms, sore throat and congestion. She mentioned she will have her 2nd dose on 08Apr2021 and asked if it was fine to test whether she was covid-19 positive or not, will there be an effect since she already got her 1st dose and could that provide false positive.  No follow-up attempts are possible. No further information is expected.