have had a headache varying from mild to severe since day 2 of the 2nd dose.; Last menstruation was on 4/27. should have started menstruation on 5/22. still have not menstruated as of 5/26.; Exhaustion has impacted my daily life since the night of the 2nd dose.; have been sleeping between 12-18 hours per day since the 2nd dose.; Injection site got progressively more itchy, red, and swollen from day 1-6 of the 2nd dose.; Injection site got progressively more itchy, red, and swollen from day 1-6 of the 2nd dose.; Injection site got progressively more itchy, red, and swollen; Days 1-2 of the 2nd dose of vaccination experienced fever; Days 1-2 of the 2nd dose of vaccination experienced fever, dizziness; Days 1-2 of the 2nd dose of vaccination experienced fever, dizziness, and was out of breath easily.; This is a spontaneous report from a contactable consumer, the patient. A 37-year-old non-pregnant female patient received the second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: EWG177) via an unspecified route of administration in the arm left on 20May2021 at 12:45 (at the age of 37-year-old) as a single dose for COVID-19 immunisation. Medical history included asthma, spinal cord problems from an injury on unknown dates. Concomitant medications were not reported. The patient had severe reaction for IV (intravenous) dyes for testing. The patient previously took erythromycin and had sensitivity towards it. The patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: EWO167) via an unspecified route of administration in the arm left on 29Apr2021 at 12:45 as a single dose for COVID-19 immunisation. Prior to the vaccination, the patient was not diagnosed with COVID-19. Since the vaccination the patient had not been tested positive for COVID-19. The patient did not receive any other vaccines within four weeks prior to the vaccination. On20May021 at 20:00, it was reported that the patient last menstruation was on 27Apr2021 and she should have started menstruation on 22May2021 however she still had not menstruated as of 26May2021. The patient had only been sexually active with her husband who had a vasectomy 10 years ago and recently tested with 0 sperm count. On an unknown date of May2021, days 1-2 of the 2nd dose of vaccination she experienced fever, dizziness and was out of breath easily. On 22May2021, the patient had a headache varying from mild to severe since day 2 of the 2nd dose. Only on date 24May2021 was severe enough to medicate with Acetaminophen, Naproxen, and Caffeine. On 20May2021, injection site got progressively more itchy, red, and swollen from day 1-6 of the 2nd dose. The effects were similar to when patient would have allergic reactions to bug bites as a child. That day was the first day when the patient noticed improvement, and the effects of the injection site were barely noticeable. On 20May2021 at 20:00, exhaustion had impacted the patient daily life since the night of the 2nd dose. She had been sleeping between 12-18 hours per day since the 2nd dose. Therapeutic measures were taken as a result of the event headache which included treatment with Acetaminophen, Naproxen, Caffeine, Tylenol and Aleve and for the event fever which included treatment with Tylenol. The events did not result in doctor or other healthcare professional office/clinic visit, and emergency room/department or urgent care. The clinical outcome of the events she should have started menstruation on 22May2021 however she still had not menstruated as of 26May2021; fever, dizziness and was out of breath easily; headache; injection site got progressively more itchy, red, and swollen from day 1-6 of the 2nd dose; was resolving while that of the events exhaustion and she had been sleeping between 12-18 hours per day since the 2nd dose was not resolved at the time of the report.