Numbness in face/face feels funny when he touches it; Numbness in arm; Felt bad; Lightheaded/Dizzy; excruciating headache; High Bood Pressure; Chest pain; Chest tightness; Panic Attacks; No energy; No appetite; Shaking; Does not feel good/laid down; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of headache in a 22-year-old male patient who received Flu Seasonal QIV Dresden (Fluarix Quadrivalent 2023-2024 season) (batch number PM35E, expiry date 30-JUN-2024) for prophylaxis.   On 29-SEP-2023, the patient received Fluarix Quadrivalent 2023-2024 season. On 02-OCT-2023, 3 days after receiving Fluarix Quadrivalent 2023-2024 season, the patient experienced headache (Verbatim: excruciating headache). On 03-OCT-2023, the patient experienced feeling bad (Verbatim: Felt bad) and light headedness (Verbatim: Lightheaded/Dizzy). On 08-OCT-2023, the patient experienced numbness facial (Verbatim: Numbness in face/face feels funny when he touches it) and numbness of upper extremities (Verbatim: Numbness in arm). In OCT-2023, the patient experienced blood pressure high (Verbatim: High Bood Pressure), chest pain (Verbatim: Chest pain), chest tightness (Verbatim: Chest tightness), panic attack (Verbatim: Panic Attacks), loss of energy (Verbatim: No energy), appetite absent (Verbatim: No appetite), tremor (Verbatim: Shaking) and feeling unwell (Verbatim: Does not feel good/laid down). The patient was treated with metoprolol tartrate (Lopressor), losartan, alprazolam (Xanax) and hydrochlorothiazide. The outcome of the headache and numbness of upper extremities were resolved and the outcome of the feeling bad, numbness facial and feeling unwell were not resolved and the outcome of the light headedness, blood pressure high, loss of energy and appetite absent were unknown and the outcome of the chest pain, chest tightness, panic attack and tremor were resolved with sequelae.   It was unknown if the reporter considered the headache, feeling bad, light headedness, blood pressure high, numbness facial, numbness of upper extremities, chest pain, chest tightness, panic attack, loss of energy, appetite absent, tremor and feeling unwell to be related to Fluarix Quadrivalent 2023-2024 season and Fluarix Tetra Pre-Filled Syringe Device.     It was unknown if the company considered the headache, feeling bad, light headedness, blood pressure high, numbness facial, numbness of upper extremities, chest pain, chest tightness, panic attack, loss of energy, appetite absent, tremor and feeling unwell to be related to Fluarix Quadrivalent 2023-2024 season and Fluarix Tetra Pre-Filled Syringe Device.   This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences.   Additional Information: GSK receipt date: 18-OCT-2023 The pharmacist stated her son (patient) received Fluarix and the following Monday, he had an excruciating headache that went away.  On Tuesday, he felt bad, was lightheaded and dizzy, and went to the ER that night. It was discovered that his blood pressure was high and they gave him Lopressor.  The patient felt bad all week on the Lopressor, at least that was what she thought made him feel bad. He went to the doctor on Friday and the doctor changed the Lopressor to take it in the morning and added Losartan to take at night. On Saturday, he went back to the ER as he woke up with numbness on the left side of his face and left arm and his blood pressure was high again when he checked it at home.  He also had chest tightness/pains.  When he got to the ER his BP had gone back down and the doctor said it was a panic attack and he was given Xanax, which made him feel a lot better.  They had done EKGs and bloodwork and those came back clear. She stated that he still had some numbness on the face, which the patient does not necessarily described as numbness but that his face felt funny when he touched it.  The reporter stated that it could be sinuses but she did not know.  The arm numbness went away kind of quick. The patient had not felt good all week, he had no energy and no appetite.  She stated he started shaking which was believed to be associated with the panic attacks of which he had another on 10th October 2023 and on 17th October 2023.  It was unknown when the shaking started but she stated that it came back on the day of reporting. He was back at school after being out for a week which she stated he just laid around as he did not felt good.  The reporter consented to follow up.