Heart hurts; Her throat is doing something funny; Has ringing in her ears worse than any tinnitus; Body pain is level 8; Somebody had to come over and care for her; Intestines hurt; Her vision was blurry; Felt stabbing pains in abdomen and back just like someone stabbing me; Right hand was so swollen she couldn't hold anything; Never had pain like this in her life; Left arm swelled to point where she couldn't make a fist; Edema went through her body, face, and neck; Felt like spinning metals; Screaming headache that was the worst migraine ever; Unable to put any pressure on feet; Feel pins and needles on whole body; General malaise and fatigue and could not stay awake; General malaise and fatigue and could not stay awake; General malaise and fatigue and could not stay awake; Arm started swelling instantly; Nauseous but did not throw up.; This spontaneous case was reported by a consumer and describes the occurrence of PERIPHERAL SWELLING (Left arm swelled to point where she couldn't make a fist), GENERALISED OEDEMA (Edema went through her body, face, and neck), VERTIGO (Felt like spinning metals), MIGRAINE (Screaming headache that was the worst migraine ever) and GAIT INABILITY (Unable to put any pressure on feet) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 025A21A and 044A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Chronic disease. Concomitant products included NEFAZODONE HYDROCHLORIDE (SERZONE), PRAMIPEXOLE DIHYDROCHLORIDE (MIRAPEX), VALACICLOVIR HYDROCHLORIDE (VALACYCLOVIR HCL), DIAZEPAM (VALIUM), ASCORBIC ACID (VITAMIN C ACID), CINNAMON [CINNAMOMUM VERUM], VITAMIN D NOS, MENAQUINONE-7 (VITAMIN K 2), CALCIUM LEVOMEFOLATE (METHYL FOLATE) and METHYLCOBALAMIN for an unknown indication.   On 03-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 31-Mar-2021, the patient experienced PERIPHERAL SWELLING (Left arm swelled to point where she couldn't make a fist), GENERALISED OEDEMA (Edema went through her body, face, and neck), VERTIGO (Felt like spinning metals), MIGRAINE (Screaming headache that was the worst migraine ever), GAIT INABILITY (Unable to put any pressure on feet), PARAESTHESIA (Feel pins and needles on whole body), MALAISE (General malaise and fatigue and could not stay awake), HYPERSOMNIA (General malaise and fatigue and could not stay awake), PAIN (Never had pain like this in her life), FATIGUE (General malaise and fatigue and could not stay awake), VACCINATION SITE SWELLING (Arm started swelling instantly) and NAUSEA (Nauseous but did not throw up.). On 01-Apr-2021, the patient experienced MALAISE (Somebody had to come over and care for her), ABDOMINAL PAIN UPPER (Intestines hurt), VISION BLURRED (Her vision was blurry), ABDOMINAL PAIN (Felt stabbing pains in abdomen and back just like someone stabbing me) and PERIPHERAL SWELLING (Right hand was so swollen she couldn't hold anything). On 02-Apr-2021, the patient experienced CHEST PAIN (Heart hurts), THROAT IRRITATION (Her throat is doing something funny), TINNITUS (Has ringing in her ears worse than any tinnitus) and PAIN (Body pain is level 8). At the time of the report, PERIPHERAL SWELLING (Left arm swelled to point where she couldn't make a fist), GENERALISED OEDEMA (Edema went through her body, face, and neck), VERTIGO (Felt like spinning metals), MIGRAINE (Screaming headache that was the worst migraine ever), GAIT INABILITY (Unable to put any pressure on feet), PARAESTHESIA (Feel pins and needles on whole body), MALAISE (General malaise and fatigue and could not stay awake), HYPERSOMNIA (General malaise and fatigue and could not stay awake), MALAISE (Somebody had to come over and care for her), ABDOMINAL PAIN UPPER (Intestines hurt), VISION BLURRED (Her vision was blurry), ABDOMINAL PAIN (Felt stabbing pains in abdomen and back just like someone stabbing me), PERIPHERAL SWELLING (Right hand was so swollen she couldn't hold anything), CHEST PAIN (Heart hurts), THROAT IRRITATION (Her throat is doing something funny), TINNITUS (Has ringing in her ears worse than any tinnitus), PAIN (Never had pain like this in her life), PAIN (Body pain is level 8), FATIGUE (General malaise and fatigue and could not stay awake), VACCINATION SITE SWELLING (Arm started swelling instantly) and NAUSEA (Nauseous but did not throw up.) outcome was unknown.            Relevant concomitant medications also included chloryphyll. Treatment details included morphine. Action taken with mRNA-1273 in response to the events was not applicable.   This case was linked to MOD-2021-066390 (Patient Link).