Doctor told to stop taking Prednisone, as it could potentially block the effect or the effectiveness of the vaccine; started feeling like had little bit of a rash on arm and back; the rash that had on back became like more intense like really itchy and both arms back; started feeling like had little bit of a rash on arm and back; the rash that had on back became like more intense like really itchy and both arms back; This is a spontaneous report from a contactable consumer or other non hcp (patient). A patient of unspecified age and gender received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: solution for injection, lot number was ER2613, and expiration date was not reported), via an unspecified route of administration on 17Mar2021 15:30 as dose 2, single for covid-19 immunization. The patient also took prednisone, via an unspecified route of administration from 21Mar2021 (Lot number was not reported) to an unspecified date, (10 mg of Prednisone on Sunday/Monday morning at 9:30 in the morning patient took 1 Prednisone another one at 2:30) for an unspecified indication. Previously patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: solution for injection, lot number was EN6200 and expiration date were not reported), via an unspecified route of administration, on 24Feb2021 as dose 1, single for COVID-19 immunization and experienced little bit of the rash on the arm. The patient medical history and concomitant medication was not reported. On an unspecified date in Mar2021, the patient experienced started feeling like had little bit of a rash on arm and back; the rash that had on back became like more intense like really itchy and both arms back. On an unspecified date, experienced Doctor told to stop taking Prednisone, as it could potentially block the effect or the effectiveness of the vaccine. Further explained that on an unspecified date in Mar2021 patient reported that had a little bit of the rash on the arm, patient mentioned it to the nurse and then she said do you want to tell your doctor first before having the second dose and then patient said oh no, no of course not, not going to let the little tiny rash get in the way of getting the second dose of the vaccine. So, then had the second dose and then coincidentally or not but the rash that have on patient back became like more intense like itchy and both arms and back. It just kind of like on lower neck, lower back and both arms, that was kind of very itchy, so then patient went to the urgent care center on Sunday and then the doctor gave 3 medications including the one that was called Prednisone 10 mg, so this was steroid. Then when spoke with doctor on Monday afternoon, he told me that he was very concerned, he told me to stop taking Prednisone (Captured suspect conservatively) right away. He said this was steroid and it could potentially block the effect or the effectiveness of the vaccine, so advise to stop steroid at all. So now concern was the following, could patient have potentially slow or blocked the effectiveness of the vaccine. The patient started taking the steroid or Prednisone, it was 4 days after the second dose of Pfizer vaccine, then on Monday morning at 9:30 in the morning took 1 Prednisone another one at 2:30. So a total of 3 that would have been a total of 30 mg in 2 consecutive days until spoke with the doctor in the afternoon or the evening of Monday night, and he told me stop taking it, he said that do not want you to take any chances of blocking the effectiveness of the vaccine and then having to maybe another boost of the vaccine or having to redo all over again. Treatment was received for itching and rash. The outcome of all events was unknown.  No follow-up attempts are possible. No further information is expected.