clot in left arm; Deep venous thrombosis in both legs; lupus erythematosus; renal deficiency; rheumatoid arthritis; arrhythmia; hemorrhages And bleeding since 25Mar2023 to date; allergies; Consecutive high blood pressure; muscle pain; pain in bones; fever; weakness in the legs; livedo reticularis; deficiency in the thyroid; fatigue; lack of energy; numbness in the fingers of the hand, feet; Rash; carpal tunnel; severe depression; anxiety episodes; low back pain; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 52-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 15Apr2021 as dose 2, single (Lot number: EW0162) at the age of 52 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Congenital Protein S deficiency" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Batch/Lot No: ER8730, Anatomical location: Left arm), administration date: 25Mar2021, when the patient was 52-year-old, for COVID-19 immunization, reaction(s): "Epiglottitis", "Allergy to grapefruit and chocolate after the first dose". The following information was reported: HYPERTENSION (disability) with onset 17May2022, outcome "not recovered", described as "Consecutive high blood pressure"; DEEP VEIN THROMBOSIS (disability) with onset 17May2022, outcome "not recovered", described as "Deep venous thrombosis in both legs"; RASH (disability) with onset 17May2022, outcome "not recovered"; HYPERSENSITIVITY (disability) with onset 17May2022, outcome "not recovered", described as "allergies"; ANXIETY (disability) with onset 17May2022, outcome "not recovered", described as "anxiety episodes"; ARRHYTHMIA (disability) with onset 17May2022, outcome "not recovered"; CARPAL TUNNEL SYNDROME (disability) with onset 17May2022, outcome "not recovered", described as "carpal tunnel"; THROMBOSIS (disability) with onset 17May2022, outcome "not recovered", described as "clot in left arm"; THYROID DISORDER (disability) with onset 17May2022, outcome "not recovered", described as "deficiency in the thyroid"; FATIGUE (disability) with onset 17May2022, outcome "not recovered"; PYREXIA (disability) with onset 17May2022, outcome "not recovered", described as "fever"; HAEMORRHAGE (disability) with onset 17May2022, outcome "not recovered", described as "hemorrhages And bleeding since 25Mar2023 to date"; ASTHENIA (disability) with onset 17May2022, outcome "not recovered", described as "lack of energy"; LIVEDO RETICULARIS (disability) with onset 17May2022, outcome "not recovered"; BACK PAIN (disability) with onset 17May2022, outcome "not recovered", described as "low back pain"; SYSTEMIC LUPUS ERYTHEMATOSUS (disability) with onset 17May2022, outcome "not recovered", described as "lupus erythematosus"; MYALGIA (disability) with onset 17May2022, outcome "not recovered", described as "muscle pain"; HYPOAESTHESIA (disability) with onset 17May2022, outcome "not recovered", described as "numbness in the fingers of the hand, feet"; BONE PAIN (disability) with onset 17May2022, outcome "not recovered", described as "pain in bones"; RENAL FAILURE (disability) with onset 17May2022, outcome "not recovered", described as "renal deficiency"; RHEUMATOID ARTHRITIS (disability) with onset 17May2022, outcome "not recovered"; DEPRESSION (disability) with onset 17May2022, outcome "not recovered", described as "severe depression"; MUSCULAR WEAKNESS (disability) with onset 17May2022, outcome "not recovered", described as "weakness in the legs". The patient underwent the following laboratory tests and procedures: Blood pressure measurement: High. Therapeutic measures were taken as a result of thrombosis, deep vein thrombosis, systemic lupus erythematosus, renal failure, rheumatoid arthritis, arrhythmia, haemorrhage, hypersensitivity, hypertension, myalgia, bone pain, pyrexia, muscular weakness, livedo reticularis, thyroid disorder, fatigue, asthenia, hypoaesthesia, rash, carpal tunnel syndrome, depression, anxiety, back pain.; Sender's Comments: Linked Report(s) : PR-PFIZER INC-202300150204 Same patient/vaccine, different dose/event (Dose1);PR-PFIZER INC-202300150205 Same patient/vaccine, different dose/event (LOE);