lost 45 pounds in only a few months.; sever tremors and involuntary movements in my arms; I had to quit my job as I was like no longer effective because I lost my steady hand,too sick to make one family meal, something I did easily before my vaccine; severe brain fog; too sick to make one family meal, something I did easily before my vaccine. I was getting sicker and sicker; involuntary movements in my arms; This spontaneous case was reported by a consumer and describes the occurrence of WEIGHT DECREASED (lost 45 pounds in only a few months.), TREMOR (sever tremors and involuntary movements in my arms), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I had to quit my job as I was like no longer effective because I lost my steady hand,too sick to make one family meal, something I did easily before my vaccine), FEELING ABNORMAL (severe brain fog) and ILLNESS (too sick to make one family meal, something I did easily before my vaccine. I was getting sicker and sicker) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 08-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 08-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced WEIGHT DECREASED (lost 45 pounds in only a few months.), TREMOR (sever tremors and involuntary movements in my arms), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I had to quit my job as I was like no longer effective because I lost my steady hand,too sick to make one family meal, something I did easily before my vaccine), FEELING ABNORMAL (severe brain fog), ILLNESS (too sick to make one family meal, something I did easily before my vaccine. I was getting sicker and sicker) and DYSKINESIA (involuntary movements in my arms). At the time of the report, WEIGHT DECREASED (lost 45 pounds in only a few months.), TREMOR (sever tremors and involuntary movements in my arms), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I had to quit my job as I was like no longer effective because I lost my steady hand,too sick to make one family meal, something I did easily before my vaccine), FEELING ABNORMAL (severe brain fog), ILLNESS (too sick to make one family meal, something I did easily before my vaccine. I was getting sicker and sicker) and DYSKINESIA (involuntary movements in my arms) outcome was unknown.            Concomitant medication was unknown.  The patient states that she was vaccinated on January 8th, 2021, and then again on February 8th, 2021. Both times Moderna. At the time the patient worked and collecting life-saving blood for blood banks. This required starting IVs over and over with precision during her shift. As a health care worker, she was eager to get vaccinated to protect herself and the people she worked with. Things didn't go as planned. The patient was not able to start IVs due to severe tremors and involuntary movements in her arms and a long list of other symptoms.   The patient had to quit her job as she was like no longer effective because she lost her steady hand and other complications were contributing to sever brain fog. For several months she could not care for her children or herself. For 8 months she was too sick to make one family meal, something she did easily before her vaccine. She was getting sicker and sicker and lost 45 pounds in only a few months.  Treatment medication was unknown.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.