woke on 28-Jul-2022, drenched and hair were wet; Felt really tired again; All  joints hurt; Low grade fever 100F; Could hardly move; Could not close her fingers; dragged herself to the kitchen; woke up with a brain fog, next morning; felt tired; feeling like she was going to die; weak; This spontaneous case was reported by a patient and describes the occurrence of FEELING ABNORMAL (feeling like she was going to die), MOBILITY DECREASED (Could hardly move), MUSCULOSKELETAL STIFFNESS (Could not close her fingers), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (dragged herself to the kitchen) and FEELING ABNORMAL (woke up with a brain fog, next morning) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 044C22A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     The patient did not had any medical history and was totally healthy prior to vaccination.    In November 2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 25-Jul-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In July 2022, the patient experienced ASTHENIA (weak). On 25-Jul-2022, the patient experienced FEELING ABNORMAL (feeling like she was going to die). On 25-Jul-2022 at 8:00 PM, the patient experienced FATIGUE (felt tired). On 26-Jul-2022, the patient experienced FEELING ABNORMAL (woke up with a brain fog, next morning). On 26-Jul-2022 at 1:00 AM, the patient experienced MOBILITY DECREASED (Could hardly move), MUSCULOSKELETAL STIFFNESS (Could not close her fingers), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (dragged herself to the kitchen), ARTHRALGIA (All  joints hurt) and PYREXIA (Low grade fever 100F). On 27-Jul-2022 at 8:00 AM, the patient experienced FATIGUE (Felt really tired again). On 28-Jul-2022, the patient experienced HYPERHIDROSIS (woke on 28-Jul-2022, drenched and hair were wet). The patient was treated with IBUPROFEN on 26-Jul-2022 at an unspecified dose and frequency. At the time of the report, FEELING ABNORMAL (feeling like she was going to die), MOBILITY DECREASED (Could hardly move), MUSCULOSKELETAL STIFFNESS (Could not close her fingers), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (dragged herself to the kitchen), FEELING ABNORMAL (woke up with a brain fog, next morning), HYPERHIDROSIS (woke on 28-Jul-2022, drenched and hair were wet), ASTHENIA (weak), FATIGUE (felt tired), ARTHRALGIA (All  joints hurt), PYREXIA (Low grade fever 100F) and FATIGUE (Felt really tired again) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 26-Jul-2022, Body temperature: 100 Around 01:00 AM, low grade fever 100F. On an unknown date, SARS-CoV-2 test: Negative.         No concomitant medication reported. It was reported on 26-JUL-2022 Tuesday morning, she woke up Dizzy, confused, and had brain fog.