immune system was messed up and weak/overreacting immune system; could not go half way without sitting down; started having flaking to the hair and leg; immune system was messed up and weak; he stated that his eyes were getting worse; This is a spontaneous report from a Pfizer sponsored program. A contactable consumer or other non hcp (patient) of 65-years-old male patient received BNT162B2 (COMIRNATY, PFIZER-BIONTECH COVID-19 VACCINE, formulation; solution for injection, lot number/Expiration date: not reported) via an unspecified route of administration, administered in Arm Left on 15Mar2021 (Age at Time of Vaccination, 65 years) at Afternoon as 2ND DOSE, SINGLE DOSE for covid-19 immunisation. patient took Covid Vaccine As soon as he could get it, 65 years and up. Medical history included hair texture abnormal from an unknown date and unknown if ongoing, rash macular from an unknown date and unknown if ongoing , psoriasis from an unknown date and unknown if ongoing , eye disorder from an unknown date and unknown if ongoing Scalia which affected eyes , ongoing diabetes mellitus Started 2 Years Ago , gastroenteritis viral from an unknown date and unknown if ongoing , skin disorder from an unknown date and unknown if ongoing , immune system disorder from an unknown date and unknown if ongoing. Concomitant medication included prednisone (PREDNISONE) taken for eye disorder, start and stop date were not reported. Patient stated that he started taking the steroid, Prednisone after the first vaccine and had the second vaccine before he was finished with the Prednisone, he was taking 80mg and then as it became the month after that they reduced it and weaned him off the steroid. No Additional Vaccines Administered on Same Date of the Pfizer Suspect. Family Medical History Relevant to AE was None. Relevant Tests were None. No medications were taken within 4 weeks, Prior to Vaccinations. No prior vaccinations following AE. Consumer said that before he received the 1st dose of the Pfizer-BioNTech Covid-19 Vaccine, he had a skin disorder which included flakiness of the hair, red blotches on his face, and psoriasis on both of his legs. He also said he had scalia, which affected his eyes. He said both of his eye doctors told him that his condition was because of an overacting immune system. He said his condition was getting worse every month. With that, he was given steroids which helped clear up his skin disorder and patient received historical vaccine bnt162b2 on 08feb2021 for covid-19 immunisation. However, he said he received the 2nd dose even before he was finished with his steroid medication. On Mar2021, the patient said at the time he received his 2nd dose, his immune system was "messed up" and weak. He added that he could not go half-way without sitting down. Patient said it took a while for him to build back his immune system but said that it was fine now. Patient said he had this skin disorder before he received either dose of the vaccine and he had no adverse events from the vaccine, his arm didn't even hurt. He wanted to make sure that he still had an immune response to the vaccine, since his immune system was so screwed up and it took so long for him to get healed up. Caller also clarified that the vaccine did not make his skin disorder worse. Caller states with his immune system so screwed up the way it was, the eye doctor said was sounded like an over-active immune system and so doctor gave him steroids and it cleared up the disorder within 2 weeks, well not completely but it was better. Patient had a skin disorders before receiving the vaccine, after receiving both doses his skin disorder started getting worse. He started having flaking to the hair and leg and also, he stated that his eyes were getting worse. The Doctor he saw have told him that it was because he had an overactive immune system. Now he was confused and wanted to know if he had immunity over Covid-19 or if the vaccine even worked since he had an overactive immune system and wanted to know if the vaccine was still effective on him. Patient stated he went to the clinic for his primary care, stated Pfizer can contact them but they are going to deny it because one time he had the stomach virus and they told him to take a test and the test came back negative. Patient was not admitted to Emergency Room or Physician Office. Outcome of the events was unknown.  Follow-up (28Mar2021): This is a follow up-spontaneous report from a contactable consumer. New information included suspect details, Concomitant medication, Clinical information.  Follow-up (28May2021): This is a follow-up spontaneous report from a Pfizer sponsored program. New information included confirmation of emergency room and physician room visit.  Further information requested.