Severe reaction to vaccine; Hives all over my neck/ hives on my back; Tightness in throat/still have tightness as if i am being choked from the inside out, on my meck and throat.; Horrible tightness in my jaw,and both sides of my neck/choked from the inside out, on my meck and throat.; Still have tightness, as if im being choked from the inside out, on my meck and throat./worsening symptoms; Horrible head rush; My head felt very hot very the inside out; Unable to work for the past week; This spontaneous case was reported by a consumer and describes the occurrence of URTICARIA (Hives all over my neck/ hives on my back), THROAT TIGHTNESS (Tightness in throat/still have tightness as if i am being choked from the inside out, on my meck and throat.), MUSCLE TIGHTNESS (Horrible tightness in my jaw,and both sides of my neck/choked from the inside out, on my meck and throat.), CHOKING SENSATION (Still have tightness, as if im being choked from the inside out, on my meck and throat./worsening symptoms) and HEAD DISCOMFORT (Horrible head rush) in a 39-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 026D21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Psoriasis. Concomitant products included APREMILAST (OTEZLA) from 2019 to an unknown date for Psoriasis.    On 29-Jul-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 29-Jul-2021, the patient experienced URTICARIA (Hives all over my neck/ hives on my back), THROAT TIGHTNESS (Tightness in throat/still have tightness as if i am being choked from the inside out, on my meck and throat.), MUSCLE TIGHTNESS (Horrible tightness in my jaw,and both sides of my neck/choked from the inside out, on my meck and throat.), CHOKING SENSATION (Still have tightness, as if im being choked from the inside out, on my meck and throat./worsening symptoms), HEAD DISCOMFORT (Horrible head rush), FEELING HOT (My head felt very hot very the inside out) and IMPAIRED WORK ABILITY (Unable to work for the past week). On an unknown date, the patient experienced VACCINATION COMPLICATION (Severe reaction to vaccine). At the time of the report, URTICARIA (Hives all over my neck/ hives on my back), THROAT TIGHTNESS (Tightness in throat/still have tightness as if i am being choked from the inside out, on my meck and throat.), MUSCLE TIGHTNESS (Horrible tightness in my jaw,and both sides of my neck/choked from the inside out, on my meck and throat.), CHOKING SENSATION (Still have tightness, as if im being choked from the inside out, on my meck and throat./worsening symptoms), HEAD DISCOMFORT (Horrible head rush), FEELING HOT (My head felt very hot very the inside out) and IMPAIRED WORK ABILITY (Unable to work for the past week) had not resolved and VACCINATION COMPLICATION (Severe reaction to vaccine) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment provided was  injection of an EPIPEN  for hives,high doses steroids and antihistamines since the 29th of July.  Patient had 'hives all over my neck.'  The Pharmacist gave patient  injection of an EPIPEN and called 911.  Patient  was taken to the Hosptial, treated and released 6 hours later.  ON 8/4/2021.  Patient is still being treated for the reaction. .   Patient has  to stay on all the meds and have been back to the ER on 8/2/2021 for worsening symptoms.  Patient is being followed by  family doctor and a new allergist that patient  just started seeing because of this incident.   Most recent FOLLOW-UP information incorporated above includes: On 04-Aug-2021: Follow up received and contains Patient information, medical history, concomitant medications, events horrible head rush, head felt very hot very the inside out, horrible tightness in my jaw, throat, and both sides of my neck.  I had hives all over my neck, still have tightness, as if im being choked from the inside out, on my meck, have been unable to work for the past week and I don't know when I will be able to return to work and throat and hives all over my neck/hives on my neck. All having outcomes Not recovered was updated.