She had a fever of 102 degrees Fahrenheit; She felt like hell.; Has lost a couple pounds; she had no energy; would sleep 5-6 hours after trips to the store; Felt very weak; Bedridden four weeks after vaccine; This is a spontaneous report from a contactable consumer or other non-healthcare professional (Patient) received from Pfizer-sponsored program. A 74-years-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot Number: EW0191, Expiry date: Unknown), via an unspecified route of administration on 06Jun2021 (at the age of 74-years-old) as dose 2, single for COVID-19 immunisation. Medical history included breast cancer from Dec1999 and ongoing carcinoma in situ Ductal carcinoma in situ, hysterectomy from an unknown date and unknown if ongoing and had surgery on Dec1999 to Dec1999. Description of complaint: Premarin: Caller said that she took Premarin that caused cancer 21 year back and will they probably take both breasts, she would have both removed. She said she had not had cancer in 21 years, they said they would take one and might need to take the other one if it would develop to cancer. Caller said she did something with the other lady, but she does not know if she did a report about Premarin, she thinks this stuff should be taken off market. Premarin NDC/LOT/EXP: Unknown. Caller said she took Premarin starting in 1985 after an emergency hysterectomy, it was recommended by a doctor because she was going nuts and wanted to kill herself, she never felt like that before she had the hysterectomy. She said she wanted to kill herself, she was rolled up in a ball, and her parents were screaming and having a fit and called the doctor. She said she started taking Premarin and in 3 days she was back to normal. She said she had a 25lb weight gain in a month, and she took Premarin from 1985-1999 without realizing it could cause breast cancer. She said she started getting breast cysts, and a surgeon went in and said something was wrong with her milk duct, it did not look right. She said they called 3 days later and said it came back as carcinoma in situ, but told her she won't have to do anything since her lymph nodes were clear. She said they did a biopsy and took a 2x2 chunk out of her breast, it was big, she was not sure if that was measured in inches or centimeters, she thinks inches, her breast dropped in size to AA, it was a scoop like an ice cream scoop. Premarin dosage unknown. She said she had beautiful thick hair before she took the Premarin. She said she took Tamoxifen for 5 years and did aggressive radiation for a month or two, maybe three months, and then she was off Premarin permanently. She said she was fine off Premarin, she did not take anything, she learned to live with the hot sweats. Concomitant medication included levothyroxine sodium (SYNTHROID) taken for an unspecified indication from Jun1965 and ongoing. The patient previously received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot Number: AW0135) via an unspecified route of administration, administered in left arm on 16May2021 for covid-19 immunization. She reported that after her first dose she was ok, her arm was sore for two days then after that it was fine. She says she did no treatment for the soreness she just moved it around and went to. She says she didn't take Aleve. She says after her second dose in June she was bedridden. The patient previously took premarin for hysterectomy and experienced cancer, tamoxifen for chemotherapy and experienced aggressive radiation. On an unspecified date in Jun2021, the patient experienced felt very weak, bedridden four weeks after vaccine, has lost a couple pounds, she had no energy, would sleep 5-6 hours after trips to the store. On 07Jun2021 experienced, she had a fever of 102 degrees Fahrenheit, she felt like hell. The patient did not received any treatment for the events. It was further reported that, caller said that she got her first dose on 16 May 2021, and then her second dose on June 06th at. She said you take them a month or so apart. She provides LOT: AW0135 or AW0185 for her first dose and says that the way it was handwritten the numbers are smoothed together. She provides LOT: EW0191 for her second dose. She felt very weak and was bedridden four weeks after getting the vaccine. Caller said it was more like 9 weeks, she did get out of bed, after two weeks she was able to get up and walk, at around 9 weeks she was able to go to the store, clarified at 3 weeks she was going to store then coming back to bed and would sleep 5-6 hours after trips to the store. She said she still falls asleep if she were to be talking like this on the phone she would have to lay down. She said she talked to a lady who got Moderna who said that she has the same thing happen to her. No further details provided about the lady who took Moderna. She said the first day after she got her second dose she had a fever of 102 degrees Fahrenheit and she felt bad. She said the second day she called her doctor because she still felt bad, her fever was down to 100 degrees Fahrenheit. She said on the third day she was doing better. She says she did not take anything to treat the fever, she did not take Aleve or anything because it would interfere with the shot. Caller said it has gotten a little bit easier, she was finally back on her exercise bike for 40 minutes a day. She says she was and was fat, she has lost a couple pounds, she was not a cripple that was bedridden she had no energy. She says she couldn't go to the gym and couldn't get out of bed after she had the Pfizer shot. She says she can go out for little trips, and if she overexerts herself she goes back to bed for an hour or two. She said she went in a month ago for her annual mammogram, which they told her yesterday they found calcifications and said there were 15 calcifications there, those are microscopic, the radiologist said they were around where had she surgery, which might explain it, and the Clinic had said sometimes you could have calcifications after you are hit in your breast, have surgery, or have aggressive radiation. She said that this may have caused it after 21 years, but what she does not understand was since she has not touched any kind of estrogen. She said her doctor today said wait 6 months to see if it changes and if it did they would take the breast off, and she asked what about the other one, and he said they would recommend that come off too if she could get it in her other breast. She said that the doctor wanted to check it in 6 months and do a second mammogram in six months and an ultrasound and if it has grown they want to take it out, they suggested a total mastectomy. She said that it would be agony to wait 6 months since it won't grow enough to spread and show beyond, it was not an aggressive cancer. Caller said she also had a friend who died after taking Premarin, her cancer came back after she took Premarin again, she was dead in 6 months. She said that that Premarin causes cancer, this also happened to her surgeon's nurse, later clarified to being her surgeon's receptionist and the friend she mentioned that died. She said the receptionist had breast cancer after she took Premarin and then a year later she saw her when she was back to work with her hair grew in and the receptionist said she can not stand the hot flashes, and went back to taking Premarin and was dead within 6 months. Caller says she had her surgery in January 2000, and then her doctor's receptionist was bald then, the receptionist was wearing a headpiece, so she asked her what happened and the receptionist said she was getting chemo treatment. She said she thinks the receptionist had chemo for a year, and then when she came back to see the surgeon the receptionist looked much better, her colour was back and she looked really good. She said the receptionist told her she had gotten symptoms back and they were horrible and she went back on Premarin and it killed her, she heard about her death from her doctor, the month or year she died she does not remember. Caller said that she can not have soy or any estrogen derivative and she has to watch her sugar because cancer grows and feeds on sugar, and she loves sugar. Tamoxifen: Caller says she went on Tamoxifen: NDC/LOT/EXP: Unknown. She says this was a chemo therapy where you take pills. Tamoxifen dosage unknown. Caller says she gained another 25lbs on Tamoxifen, and had some hair loss, and she used something called Nioxin which works and put hair back on her head. Caller said that they had discontinued her Tamoxifen on and off for three weeks because she kept vomiting, and then she took it for 5 years. Caller said that she would like to tell Pfizer to please stop the cruelty with Premarin and testing, somehow in the lab they are not testing, they are giving horrible beatings to the horses and have them tied down to get the urine for hormones, it was made from horse urine. She said she never would have taken Premarin if she had known this, she would rather have had the shakes and stuff you have when you have a sudden hysterectomy. She says that the pictures she saw makes her stomach sick, Pfizer has to work on the cruelty to animals, and take the urine humanely. She says there was a big petition about this going on. She says she also hopes no more women die from this or lose their breasts. When they found the DCIS. Had surgery Dec1999. Now I have calcification and will know if they are cancerous in six months. I have been disfigured from the danger in Dec1999. No admission to hospital due to the event. The patient underwent lab tests and procedures which included biopsy: 2x2 chunk out of her breast her breast dropped in size to AA, mammogram: calcifications (15 calcifications there), weight: 25lb (weight gain in a month Caller says she gained another 25lbs on Tamoxifen) on an unknown date. body temperature: 102 fahrenheit on 07Jun2021, body temperature: 100 fahrenheit on Jun2021. The outcome of the event asthenia was reported as unknown while for the other events was reported as recovering.  Follow-Up (08Oct2021): Follow-up attempts are completed. No further information is expected.