This case was reported by a lawyer and described the occurrence of joint pain in a female subject of unspecified age who was vaccinated with LYMERIX (GlaxoSmithKline). A physician or other health care professional has not verified this report. On an unspecified date the subject received unspecified dose of LYMERIX (unknown). On an unspecified date after vaccination with LYMERIX, the subject experienced joint pain, fatigue, flu-like symptoms, headaches, Raynaud's Phenomenon, tremors, insomnia, tingling, numbness, shooting pains, possible memory loss decreased activities of daily life, rheumatologic, neurologic, and/or cognitive impairment of an autoimmune, immune-mediated or other mechanism, all reported to be caused by vaccination with LYMERIX. The subject also has decreased activities of daily life. At the time of reporting the outcome of the events was unspecified. This information was received via a Statement of Injuries. Follow-up information was received in the form of a claimant interview on 13 February 2009. Conditions of hand tremor, osteopenia and insomnia were reported as medical history and high cholesterol was indicated as past medical history. The subject reported that he received three doses of LYMERIX vaccine with the first administered on 29 March 1999, the 2nd on 29 April 1999 and the 3rd on 20 March 2000. Following vaccination with LYMERIX, the subject reported that she developed neck and shoulder pain for which she took Naproxen, VIOXX, FLEXERIL, ELAVIL, ZITHROMAX and MOBIC. She also reported general pain flare ups. Both events remain unresolved. The subject developed a peptic ulcer in late 2000 for which she received PEPCID. The ulcer has resolved. In 2001, the subject reportedly developed memory and concentration problems as well as fatigue and in late 2001, developed high blood pressure (treated with LISINOPRIL), lumbar pain (treated with ibuprofen, VIOXX and MEDROL DOSEPAK), incomplete voiding, thoracic pain and frozen shoulder. The later two have resolved, the others continue. In 2002, the subject experienced rash which was reportedly shingles which resolved after treatment with topical ointment. In 2003, the subject developed hip pain (treated with ibuprofen, VIOXX and ZITHROMAX), vertigo, tingling (specifically mentioned were the face and feet), numbness of the feet (treated with ibuprofen and VIOXX) and Achilles tendon pain, hamstring pain and frozen finger all treated all ibuprofen and VIOXX. All of these events were said to have resolved with the exception of hip pain. Also reported was toe pain beginning in 2004 which was treated with ibuprofen and VIOXX. The event resolved. In 2005, hearing loss was reported which remains unresolved. Jaw pain and foot pain were experienced in 2007 and have resolved. In 2008, the subject developed thumb joint pain which continues and has been treated with ibuprofen, CELEBREX and MOBIC and also burning and inflammation of the tongue which continues. All of the above mentioned events were considered by the subject to be attributable to LYMERIX vaccination. Kidney cyst and dense nodule in breast were reported by the subject as events beginning post LYMERIX, however, not attributable to vaccination. Additional medications reported but not known as treatment or concurrent medications included PREMARIN, VOLTAREN cream, Multivitamin, low dose aspirin, Glucosamine, Chondroitin, Magnesium, Calcium, Selenium, Tiger balm and TENS unit.