hives; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  An 81-year-old female patient received BNT162b2 (BNT162B2), on 31Mar2021 as dose 2, single (Lot number: ER8737) at the age of 81 years for covid-19 immunisation. The patient's relevant medical history included: "Scoliosis" (ongoing), notes: scoliosis was diagnosed at least 10 years or 7-8 years ago; "Osteoporosis" (ongoing); "Arthritis" (ongoing); "spinal stenosis" (ongoing); "she had polio as a child" (unspecified if ongoing), notes: she had polio as a child; "two little fractures in her lower bones in her back" (unspecified if ongoing), notes: two little fractures in her lower bones in her back; "she also has a walker she uses" (unspecified if ongoing), notes: she also has a walker she uses. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Lot No: EN6208), administration date: 10Mar2021, when the patient was 81-year-old, for Covid-19 immunization, reaction(s): "Hives". The following information was reported: URTICARIA (medically significant) with onset Mar2021, outcome "not recovered", described as "hives". The event "hives" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Blood test: Unknown results, notes: Had a lot of blood tests and they were trying to figure out why the hives and apparently the doctor figured it was the Pfizer vaccine; Body height: 5 feet 5 inches. Therapeutic measures were taken as a result of urticaria. Additional information: For her Pfizer Covid vaccine, the 1st was administered on 10Mar2021 with lot EN6208; the 2nd dose was administered on 31Mar2021 with ER8737 at the same facility; the booster dose was on 04Oct2021 with lot FF8811. Since she had the injections she had been dealing with severe outbreak of hives just on the right side and so she had gone to her primary care physician and dermatologist over and over these three years and they do not know what to do. She was sent to an allergist and they did an extreme amount of blood tests and checked her and the hives and came to the conclusion that the hives were caused by the Pfizer Injection. She was age 81 when the hives began as it was Mar2021 and after two vaccines and then the booster. As of Dec2022 she was started on injections in each arm called Xlara (also reported as Explar, Xlair) and carries an epi-pen with it and her last injection of Xlara was Friday and her hives were unbelievable at time of reporting and she could not believe nothing was working. When she first started going to the provider, she thought back in October or November of last year, she had the Xlair injections and had two of them one in each arm and the first three times she did that she would sit in the waiting room for 2 hours and was then ready to go and had to be alert in case she went into whatever and had not had to use her epi-pen; the Xlair injections began Dec2022 or so about in October or Nov2022 was when she started seeing him because her primary care and dermatologist gave up; they were putting her on prednisone all the time and that's not safe.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300233528 same patient, different dose;US-PFIZER INC-202300232978 same patient, different dose;