Squamous cell carcinoma in situ (SCCIS) of skin of finger of left hand; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 78-year-old male patient received BNT162b2 (BNT162B2), on 26Sep2021 as dose 3 (booster), single (Lot number: FF2589) at the age of 76 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "Paroxysmal atrial fibrillation" (unspecified if ongoing); "Hypothyroidism" (unspecified if ongoing); "Hypercholesterolemia" (unspecified if ongoing); "Migraine" (unspecified if ongoing); "Sinus bradycardia" (unspecified if ongoing); "Prostatitis" (unspecified if ongoing); "Metatarsalgia" (unspecified if ongoing); "Primary open angle glaucoma, right eye, moderate stage" (unspecified if ongoing), notes: Primary open angle glaucoma, right eye, moderate stage; "Blepharitis" (unspecified if ongoing); "Eczema" (unspecified if ongoing); "Aortic valve stenosis" (unspecified if ongoing); "Heart valve replaced by transplant", start date: Apr2002 (unspecified if ongoing), notes: Added 18Feb2011; "Epistaxis" (unspecified if ongoing), notes: Added 08Nov2013; "Ascending aorta dilatation" (unspecified if ongoing), notes: Ascending aorta dilatation, Added 29Jul2021; "Indeterminate stage chronic open angle glaucoma" (unspecified if ongoing), notes: Indeterminate stage chronic open angle glaucoma, Added 28Mar2013; "Nearsightedness" (unspecified if ongoing), notes: Nearsightedness, Added 23Jan2017; "Cataract" (unspecified if ongoing), notes: Added 17Aug2015; "Presence of artificial intraocular lens" (unspecified if ongoing), notes: Presence of artificial intraocular lens, Added 21Apr2010; "Meibomian gland disease left" (unspecified if ongoing), notes: Meibomian gland disease left, Added 03Jul2018; "Fungal nail infection" (unspecified if ongoing), notes: Fungal nail infection, Added 13Sep2018; "Tinea pedis of both feet" (unspecified if ongoing), notes: Tinea pedis of both feet, Added 13Sep2018; "Pain in soft tissues of limb" (unspecified if ongoing), notes: Pain in soft tissues of limb, Added 13Sep2018; "Coagulation disorder due to circulating anti coagulants" (unspecified if ongoing), notes: Coagulation disorder due to circulating anti coagulants, Added 13Sep2018; "Onychomycosis of right great toe" (unspecified if ongoing), notes: Onychomycosis of right great toe, Added 08Aug2019; "Fingernail abnormalities" (unspecified if ongoing), notes: Fingernail abnormalities, Added 08Aug2019; "Actinic keratosis" (unspecified if ongoing), notes: Added 31Oct2019; "Skin growth" (unspecified if ongoing), notes: Added 31Oct2019. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Dose: 1, Anatomical site of injection: Arm, Batch/lot number: EL 9262), administration date: 26Jan2021, when the patient was 76-year-old, for COVID-19 immunization; BNT162b2 (Dose: 2, Anatomical site of injection: Arm, Batch/lot number: EN 6201), administration date: 16Feb2021, when the patient was 76-year-old, for COVID-19 immunization. The following information was reported: SQUAMOUS CELL CARCINOMA (medically significant) with onset 28Dec2021, outcome "unknown", described as "Squamous cell carcinoma in situ (SCCIS) of skin of finger of left hand". The patient underwent the following laboratory tests and procedures: Hepatitis C antibody: (16Dec2022) Reactive, notes: Your value Reactive, Flag: A. Therapeutic measures were taken as a result of squamous cell carcinoma.