He is reporting that the last couple of months, he has been experiencing a very bitter taste in his mouth that is there all day long; prostate cancer; Headache; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 68-year-old male patient received BNT162b2 (BNT162B2), on 21Apr2021 at 08:15 as dose 2, single (Batch/Lot number: unknown) at the age of 66 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "vision disability" (unspecified if ongoing), notes: The vision disability he has had his whole life; "blood pressure" (ongoing), notes: He was on blood pressure medication. The patient took concomitant medications. Vaccination history included: Bnt162b2 (Dose 1, Single; was approximately 3 weeks prior to 2nd shot), administration date: 2021, for COVID-19 immunization, reaction(s): "Blindness", "Condition aggravated". Prior Vaccinations (within 4 weeks) were none and family medical history relevant to adverse events was none. The injection was in left arm between elbow and shoulder. No other conditions, no investigations and no other products. Indication for use included governor saying if you were not vaccinated, you would not be allowed in supermarket and if he cannot get in supermarket, he will starve to death, because he lives alone. The following information was reported: PROSTATE CANCER (medically significant) with onset Jan2022, outcome "recovering"; HEADACHE (non-serious) with onset 2022, outcome "unknown"; DYSGEUSIA (non-serious) with onset Oct2022, outcome "recovering", described as "He is reporting that the last couple of months, he has been experiencing a very bitter taste in his mouth that is there all day long". The events "prostate cancer" and "he is reporting that the last couple of months, he has been experiencing a very bitter taste in his mouth that is there all day long" required physician office visit. The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (unspecified date) Unknown Results, notes: At the time of the vaccine he was in perfect health except his blood pressure; Prostatic specific antigen: (unspecified date) Normal, notes: Before the vaccine, for 7-8 years, his PSA was completely normal; (unspecified date) high, notes: Around 6 months after getting the vaccine, his PSA went sky high and he was diagnosed with prostate cancer; (Oct2022) went from 9.7 all the way down to 2.7, notes: His PSA, according to the blood work on Oct2022, went from 9.7 all the way down to 2.7 and he had to go recheck it 2-3 times to make sure that was right and she said it is correct and the medication is helping for lowering the PSA. Therapeutic measures were taken as a result of prostate cancer. Clinical course: He was on blood pressure medication, but that has never been a problem with the bitter taste. No idea of the name. At the time of the vaccine, he was in perfect health except his blood pressure. He received 2 shots of the Pfizer COVID-19 Vaccine and had not received any booster dose. For 1st dose, unknown exact date, but provided as approximately 3 weeks prior to 2nd dose given on 21Apr2021. Time for 2nd dose was 08:15 at Mass Vaccine site at a mall. He was reporting that the last couple of months, he has been experiencing a very bitter taste in his mouth that was there all day long. He had consulted with his dentist and his dentist was not aware of it, did not know how to get rid of it. Patient wanted to know how to get rid of this bitter taste, is there a solution he can swish around, or will it disappear on its own. A few months ago, patient started experiencing a problem involving his mouth, he started getting a very bitter taste in my mouth and it was there 24 hours a day; Patient still had it. Patient further stated, unfortunately he had a vision disability (Intent: Medical history), so he got to get a magnifying glass, so hold on. The vision disability he has had his whole life. When this first bitter taste started happening, he could not figure out why he had it and then caught tail end of news story and it said it was connected to the vaccine. He stated that reading and writing were something he did not do very well. He stated he had a headache right now (in2022) and did not wish to complete 3 question survey after completion of the call. The bitter taste started at the end of Oct2022. Little less now, than what it was in the previous 4-6 weeks, still there though. Before the vaccine, for 7-8 years, his PSA was completely normal. Around 6 months after getting the vaccine, his PSA went sky high and he was diagnosed with prostate cancer. He first went to Urologist Nov2021, and in Jan2022, after going through biopsy surgery, which was pretty major surgery, they diagnosed him with Prostate cancer. Confirmed this was outpatient procedure and he was not hospitalized for greater than 24 hours. For the last 6 months has been on medication to lower his PSA and he does not know the name of it.  He has been getting tested every 3 months. Nothing has happened as far as removing the cancer or anything like that. Everything has been status quo except for this medication he has been on for the last 6 months. His PSA, according to the blood work on Oct2022, went from 9.7 all the way down to 2.7 and he had to go recheck it 2-3 times to make sure that was right, and she said it was correct and the medication was helping for lowering the PSA. It was not supposed to shrink the cancer, just the PSA. He was going back in Jan2023 to see the doctor, so he will not know if it was any better or worse until then. Reportedly, serious was no.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201362208 same patient, different vaccine dose/event;