Tested positive again; Tested positive for Covid; This spontaneous case was reported by a patient and describes the occurrence of COVID-19 (Tested positive for Covid) and COVID-19 (Tested positive again) in a 58-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No Medical History information was reported.   On 01-Mar-2021 at 1:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 29-Mar-2021 at 12:00 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Nov-2021 at 2:15 PM, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In April 2022, the patient experienced COVID-19 (Tested positive for Covid). In May 2022, the patient experienced COVID-19 (Tested positive again). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) from 27-Apr-2022 to 01-May-2022 for COVID-19 treatment, at an unspecified dose and frequency. In May 2022, COVID-19 (Tested positive for Covid) had resolved. At the time of the report, COVID-19 (Tested positive again) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In April 2022, SARS-CoV-2 test: positive (Positive) Tested positive for Covid. In May 2022, SARS-CoV-2 test: positive (Positive) Tested positive again and negative (Negative) Tested negative.         Concomitant medication information was not provided by the reporter.  On an unknown date in Apr-2022, the patient was exposed at a dinner party. Two days later felt slight symptoms and tested positive for Covid. Started Paxlovid 48 hours later and completed course (five days).   On an unknown date in May-2022, the patient felt fine and tested negative.   On 04-May-2022, four days later he developed a slight cough (thought it was allergies).  On an unknown date in May-2022, a few days later he was stuffy and had blowing nose all the time. Two days later he felt weak and foggy. The patient tested positive again and felt terrible on 16-May-2022.  Device date was reported as 16-May-2022.  Company Comment:  This is a spontaneous case concerning a 58-year-old male patient with no medical history reported, who experienced the unexpected non-serious adverse event of special interest COVID-19 (reported as COVID-19 and COVID-19 recurrent), which occurred after receiving the third dose of mRNA-1273 vaccine. The first episode of COVID-19 occurred approximately 5 months after the third dose, while the event COVID-19 recurrent occurred approximately 6 months post-vaccination. Patient received 2 doses of mRNA-1273 vaccine with 28 days interval, approximately 8 months prior to the third dose. Initially, patient felt slight unspecified symptoms and was tested positive for COVID-19. Patient was treated with Paxlovid 48 hours later and completed course for five days. Few days later, patient developed a slight cough, stuffy nose, felt weak and foggy and tested positive again for COVID-19. Patient reported that the first episode of COVID-19 had resolved, while the COVID-19 recurrent was not yet resolved. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This is a spontaneous case concerning a 58-year-old male patient with no medical history reported, who experienced the unexpected non-serious adverse event of special interest COVID-19 (reported as COVID-19 and COVID-19 recurrent), which occurred after receiving the third dose of mRNA-1273 vaccine. The first episode of COVID-19 occurred approximately 5 months after the third dose, while the event COVID-19 recurrent occurred approximately 6 months post-vaccination. Patient received 2 doses of mRNA-1273 vaccine with 28 days interval, approximately 8 months prior to the third dose. Initially, patient felt slight unspecified symptoms and was tested positive for COVID-19. Patient was treated with Paxlovid 48 hours later and completed course for five days. Few days later, patient developed a slight cough, stuffy nose, felt weak and foggy and tested positive again for COVID-19. Patient reported that the first episode of COVID-19 had resolved, while the COVID-19 recurrent was not yet resolved. The benefit-risk relationship of mRNA-1273 is not affected by this report.