She reports that she has been sick for two weeks; I'm not clear in my head; She had Fever, Myalgia, and Diarrhea; She had Fever, Myalgia, and Diarrhea; She had Fever, Myalgia, and Diarrhea; She has Fatigue; she had severe headache; She still has a little swelling on the injected arm injection site; This spontaneous case was reported by a physician and describes the occurrence of ILLNESS (She reports that she has been sick for two weeks), BRAIN FOG (I'm not clear in my head), DIARRHOEA (She had Fever, Myalgia, and Diarrhea), PYREXIA (She had Fever, Myalgia, and Diarrhea) and MYALGIA (She had Fever, Myalgia, and Diarrhea) in a 62-year-old female patient who received mRNA-1273.815 (SPIKEVAX 2023-2024) (batch no. 303147) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 03-Nov-2023, the patient received sixth dose of mRNA-1273.815 (SPIKEVAX 2023-2024) (unknown route) 1 dosage form. On 04-Nov-2023, the patient experienced ILLNESS (She reports that she has been sick for two weeks), BRAIN FOG (I'm not clear in my head), DIARRHOEA (She had Fever, Myalgia, and Diarrhea), PYREXIA (She had Fever, Myalgia, and Diarrhea), MYALGIA (She had Fever, Myalgia, and Diarrhea), FATIGUE (She has Fatigue), HEADACHE (she had severe headache) and VACCINATION SITE SWELLING (She still has a little swelling on the injected arm injection site). The patient was treated with PARACETAMOL (TYLENOL) at an unspecified dose and frequency. At the time of the report, ILLNESS (She reports that she has been sick for two weeks), BRAIN FOG (I'm not clear in my head), DIARRHOEA (She had Fever, Myalgia, and Diarrhea), PYREXIA (She had Fever, Myalgia, and Diarrhea), MYALGIA (She had Fever, Myalgia, and Diarrhea), FATIGUE (She has Fatigue) and VACCINATION SITE SWELLING (She still has a little swelling on the injected arm injection site) had not resolved and HEADACHE (she had severe headache) had resolved.        mRNA-1273.815 (SPIKEVAX 2023-2024) (Unknown) was withdrawn on an unknown date.   For mRNA-1273.815 (SPIKEVAX 2023-2024) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were reported.  Reported that patient states that every time she got vaccinated, she got sicker and sicker. She had 5 vaccines mix of Pfizer and Moderna. She had side effects and felt sick after Pfizer and Moderna COVID-19 vaccination. She still has a little swelling on the injected arm injection site. The swelling was horrible the first day. She states, "I'm so sick. I can't go to work.  She was taking Tylenol. and fluids.  She has not done a COVID test after vaccination. All her tests prior to vaccination were negative.  She stated that she was exposed to somebody who has covid.  She stated that, "It seems like, I'm so sick every time I have the vaccine. I progressively have gotten sick or sicker. So, no more vaccine for me. Spikevax is the worst, I've never been so sick. I haven't worked for two weeks. I'm not clear in my head."  Patient husband had cancer. She took Vaccine to keep her husband healthy because he was immunocompromised.   She exposed to patients every day, but she wears a mask all the time at work. Since her symptoms began a day after vaccination on 04NOV2023, she referred them as a side effect of the vaccine.   This case was linked to US-MODERNATX, INC.-MOD-2023-750053 (Linked Report).   Reporter did not allow further contact; Sender's Comments:  US-MODERNATX, INC.-MOD-2023-750053:Same reporter Monovalent case