At the end of February, legs still hurt; Put her to bed/Could hardly get out of bed; Several months of walking with canes; couldn't move the next day because she was in so much pain; break in wrist; Every joint in her body hurt; Arthritis worsening; This spontaneous case was reported by a patient and describes the occurrence of ARTHRITIS (Arthritis worsening), HYPOKINESIA (Put her to bed/Could hardly get out of bed), GAIT DISTURBANCE (Several months of walking with canes), PAIN (couldn't move the next day because she was in so much pain) and WRIST FRACTURE (break in wrist) in an 82-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 039F21A, 030M20A and 043L20A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Bee sting hypersensitivity, Shellfish allergy (get a rash or get nauseated when eat fish), Drug allergy (Sulfa), Drug allergy (Demerol), Drug allergy (omega XL), Arthritis (Arthritis in knees, hip, back, and shoulders and condition was worsening.) and Blood pressure high. Concomitant products included ATENOLOL and AMLODIPINE BESYLATE for Blood pressure high, PRAVASTATIN SODIUM (PRAVASTATIN [PRAVASTATIN SODIUM]), LOSARTAN POTASSIUM and LEVOTHYROXINE SODIUM (SYNTHROID) for an unknown indication.   On 22-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 milliliter. On 15-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .5 milliliter. On 03-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .5 milliliter. On 03-Nov-2021, the patient experienced ARTHRITIS (Arthritis worsening), PAIN (couldn't move the next day because she was in so much pain), WRIST FRACTURE (break in wrist) and ARTHRALGIA (Every joint in her body hurt). On 04-Nov-2021, the patient experienced HYPOKINESIA (Put her to bed/Could hardly get out of bed) and GAIT DISTURBANCE (Several months of walking with canes). On 28-Feb-2022, the patient experienced PAIN IN EXTREMITY (At the end of February, legs still hurt). The patient was treated with IBUPROFEN at an unspecified dose and frequency. At the time of the report, ARTHRITIS (Arthritis worsening) had not resolved and HYPOKINESIA (Put her to bed/Could hardly get out of bed), GAIT DISTURBANCE (Several months of walking with canes), PAIN (couldn't move the next day because she was in so much pain), WRIST FRACTURE (break in wrist), ARTHRALGIA (Every joint in her body hurt) and PAIN IN EXTREMITY (At the end of February, legs still hurt) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: raised Raised. On an unknown date, X-ray: normal Normal and 2 sets of x-rays to find break in wrist. 2 sets of x-rays to find break in wrist..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No other vaccines given within 1 month prior to Moderna COVID-19 vaccine and did not experienced a similar event in the past. Patient was immunocompromised. She had taken ibuprofen due that patient blood pressure raised. She reported that, she was fine now and was doing exercises, walking a little bit, and feeling fine. It took months getting over and she was scared about ever to get another booster. For the booster dose, She reported that her card has dose 1 or 2 stamped and 2 was circled, so patient may have received 3rd dose instead with the it being a full dose.  Company comment: This spontaneous case reported by a consumer concerns a 82-year-old, female patient with no relevant medical history reported, who experienced the unexpected, non-serious AESI of Arthritis (arthritis worsening), on the same day, after receiving the 3 dose of mRNA1273 vaccine in the covid 19 vaccination series, along with other non serious events of Hypokinesia, Gait disturbance, Pain and wrist fracture. Concurrent medical conditions included Arthritis (Arthritis in knees, hip, back, and shoulders and the condition was worsening.), which along with advanced age of the subject could be the confounders to the event. The patient was treated with ibuprofen. The event had not resolved. On an unknown date, X-ray was normal and 2 sets of x-rays were done to find break in wrist. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-598102 (Patient Link).; Sender's Comments: This spontaneous case reported by a consumer concerns a 82-year-old, female patient with no relevant medical history reported, who experienced the unexpected, non-serious AESI of Arthritis (arthritis worsening), on the same day, after receiving the 3 dose of mRNA1273 vaccine in the covid 19 vaccination series, along with other non serious events of Hypokinesia, Gait disturbance, Pain and wrist fracture. Concurrent medical conditions included Arthritis (Arthritis in knees, hip, back, and shoulders and the condition was worsening.), which along with advanced age of the subject could be the confounders to the event. The patient was treated with ibuprofen. The event had not resolved. On an unknown date, X-ray was normal and 2 sets of x-rays were done to find break in wrist. The benefit-risk relationship of mRNA-1273 is not affected by this report.