swollen Lymph Nodes on Left Side under the arm on the same side as the injection starting the same day as the vaccine for both doses; Ankles Swollen Allergic Reaction / aggravated an allergy/ her reaction was worse; 2nd dose she developed swollen ankles / Ankles Swollen Allergic Reaction; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team for a Pfizer sponsored program (159558). The reporter is the patient.  A 49 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 07May2021 (Lot number: EW0170) at the age of 49 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Chronic Lyme Disease" (unspecified if ongoing), notes: suspected; "allergy to Nickel" (unspecified if ongoing); "allergy to Ethylenediamine Dihydrochloride" (unspecified if ongoing); "allergic to other cleaning products" (unspecified if ongoing). Concomitant medication(s) included: DOXYCYCLINE taken for suspected Chronic Lyme Disease and allergy to Nickel and Ethylenediamine Dihydrochloride. Vaccination history included: Bnt162b2 (Dose 1, Lot: EW0162, same side as the injection starting the same day as the vaccine), administration date: 16Apr2021, when the patient was 49 years old, for Covid-19 Immunization, reaction(s): "Swollen Lymph Nodes on Left Side". The following information was reported: VACCINATION SITE LYMPHADENOPATHY (medically significant) with onset 07May2021, outcome "recovered" (2021), described as "swollen Lymph Nodes on Left Side under the arm on the same side as the injection starting the same day as the vaccine for both doses"; HYPERSENSITIVITY (medically significant) with onset 2021, outcome "recovered" (2021), described as "Ankles Swollen Allergic Reaction / aggravated an allergy/ her reaction was worse"; JOINT SWELLING (medically significant) with onset 2021, outcome "recovered" (2021), described as "2nd dose she developed swollen ankles / Ankles Swollen Allergic Reaction". The events "swollen lymph nodes on left side under the arm on the same side as the injection starting the same day as the vaccine for both doses", "ankles swollen allergic reaction / aggravated an allergy/ her reaction was worse" and "2nd dose she developed swollen ankles / ankles swollen allergic reaction" were evaluated at the physician office visit. Therapeutic measures were taken as a result of vaccination site lymphadenopathy, hypersensitivity, joint swelling. Clinical course: Patient received her 1st and 2nd doses of the Pfizer BTC vaccine in Apr and May. After the 1st dose swollen lymph nodes under her arm on the side that she had the injection on, which she saw was common. Swollen Lymph Nodes on Left Side was reported as started on the day of the vaccine and lasted for a week or two after the vaccine. It was swollen under the arm on the same side as the injection starting the same day as the vaccine for both doses. Also, after her Second Dose, she developed swollen ankles pretty bad. She took BENADRYL and it reduced the swelling. She saw an Allergist since the BENADRYL reduced the swelling and found out she is allergic to a chemical and metal. She has been allergic to nickel and other cleaning products. She doesn't know if the vaccine caused her to have an allergic reaction or aggravated an allergy. Patient has an allergy to nickel and ethylenediamine dihydrochloride and queried if these were present in the vaccine. She didn't attribute it to the Pfizer Covid vaccine but maybe her reaction was worse and it may be related. She doesn't believe it is a new allergy but that it is worse at the time of report. Reporter seriousness for Second Dose: Swollen Lymph Nodes on Left Side and Ankles Swollen Allergic Reaction was Unspecified.  No follow-up attempts are possible. No further information is expected.