Information has been received form a licensed practical nurse concerning a 4 year old female with lice infestation who on 14, Dec 2006 was vaccinated measles virus vaccine live (Enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus vaccine live (Wistar RA 27/3) (+) varicella virus vaccine live (Oka/Merck upgrade process) (lot # 653463/0463F). Concomitant therapy that day included permethrin and diphtheria toxoid (+) hepatitis B virus vaccine rHBsAg (yeast) (+) pertussis acellular 3-component vaccine (+) poliovirus vaccine inactivated (vero) (+) tetanus toxoid (PEDIARIX). On 08, Jan 2007. the patient experienced a rash and was diagnosed with contact dermatitis. Medical attention was sought and treatment included hydrocortisone cream which did not decreased the rash. On 11 Jan 2007, the patient was vaccinated with measles virus vaccine live (Enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus vaccine live (Wistar RA 27/3) (MSD), poliovirus vaccine (unspecified) and diphtheria toxoid (+) pertussis acellular vaccine (unspecified) (+) tetanus toxoid. On 23, Jan 2007, the patient was diagnosed with shingles in the left inguinal ligament area. A patch of microvesicular lesions measuring 6 cm by 5 cm in size was noted in this area, which was dry with no drainage. VZV analysis by PCR was not offered at the time of this report. The patient's contact dermatitis and shingles persisted. No additional information to report. There was no product quality complaint involved. Follow-up information regarding the VZV ID PCR results indicated that the sample for this case was inadequate. Additional information has been requested. This is in follow-up to report (s) previously submitted on 4/4/2007. Information has been received from a licensed practical nurse concerning a 4-year-old female with a history of measles at age 2 and with lice infestation and a penicillin and a KEFLEX allergy who on 14-DEC-2006 was vaccinated SC in the right thigh with a 0.5ml dose of PROQUAD (Lot # 653463/0463F). Concomitant therapy that day included PEDIARIX. On 09-JAN-2007, the patient experienced a rash and was diagnosed with contact dermatitis. Medical attention was sought and treatment included hyrocortisone cream which did not decrease the rash. On 11-JAN-2007, the patient was vaccinated with PROQUAD. On 23-JAN-2007, the patient was diagnosed with shingles in the left induinal ligament area. A patch of microvesicular lesions measuring 6 cm by 5 cm in size was noted in this area, which was dry with no drainage. VZV analysis by PCR was not offered at the time of this report. Thepatient's contact dematitis and shingles persisted. No additional information to report. There was no product quality complaint involved. Follow up information received indicated that on 17-DEC-2006, the patient developed a temperature of 98.5 and a vesicular rash on the left lower quandrant of the abdomen (left t-12). The rash occurred at the site of injection or elswhere within 42 days of the vaccination. On 02-FEB-2007, a specimen  noted to be crusted vesicular leasions with surrounding erythema on the left lower quadrant of the abdomen were sent for PCR. Herpes zoster was noted three days post vaccination (on 17-DCE-2006). No photo was taken. VZV INA was not amplified. B-globin INA was not amplified. TheVZV ID PCR results indicated that the sample for this case was inadequate, negative for B-globin with no strain indentification. The outcome was recovered. No additional information is expected.