Blood test reveals meaningful inflammation; Difficulty in sleeping; Pain in lower back; Muscle weakness/ Weakness in my right legs; Pain in shoulder/ especially limbs; Experiencing shoulders pain especially when i rotate my arms to right/ periodic pain and discomfort in my wrist and thumbs/Pain in hips; This spontaneous case was reported by a consumer and describes the occurrence of INFLAMMATION (Blood test reveals meaningful inflammation), SLEEP DISORDER (Difficulty in sleeping), BACK PAIN (Pain in lower back), MUSCULAR WEAKNESS (Muscle weakness/ Weakness in my right legs) and MYALGIA (Pain in shoulder/ especially limbs) in an 81-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 032120A and 011220A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Psoriasis (psoriasis) since 1990. Concurrent medical conditions included Polycythemia vera (polycythemia vera) since 2015, Chronic lymphocytic leukemia (chronic lymphocytic leukemia) since 2015, Herpes on lip (lip herpes) since 1985, Drug allergy (Sulfa drugs), Drug allergy (diamox) and Drug allergy (amplodomine besylate). Concomitant products included LISINOPRIL from 01-Dec-2020 to an unknown date for Blood pressure high, CALCIUM CITRATE, COLECALCIFEROL (CITRACAL-D) for Calcium, ATORVASTATIN for Cholesterol, HYDROXYUREA for Chronic lymphocytic leukemia.   On 21-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 15-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 17-Feb-2021, the patient experienced INFLAMMATION (Blood test reveals meaningful inflammation), SLEEP DISORDER (Difficulty in sleeping), BACK PAIN (Pain in lower back), MUSCULAR WEAKNESS (Muscle weakness/ Weakness in my right legs), MYALGIA (Pain in shoulder/ especially limbs) and ARTHRALGIA (Experiencing shoulders pain especially when i rotate my arms to right/ periodic pain and discomfort in my wrist and thumbs/Pain in hips). The patient was treated with NAPROXEN SODIUM (ALEVE) for Pain, at an unspecified dose and frequency; PARACETAMOL (TYLENOL) for Pain, at an unspecified dose and frequency and PREDNISONE ongoing since an unknown date at a dose of 3 milligram. At the time of the report, INFLAMMATION (Blood test reveals meaningful inflammation), MYALGIA (Pain in shoulder/ especially limbs) and ARTHRALGIA (Experiencing shoulders pain especially when i rotate my arms to right/ periodic pain and discomfort in my wrist and thumbs/Pain in hips) had not resolved, SLEEP DISORDER (Difficulty in sleeping) and MUSCULAR WEAKNESS (Muscle weakness/ Weakness in my right legs) outcome was unknown and BACK PAIN (Pain in lower back) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 17-Mar-2021, Blood test: abnormal (abnormal) abnormal.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Patient took prednisone initially 10 mg per day then reduced to 5 mg per day then reduced to 4 mg per day and was currently at 3 mg per day.  Patient was no longer experiencing pain in lower back and hips. Blood tests did not show arthritis.   Most recent FOLLOW-UP information incorporated above includes: On 15-Jul-2021: significant follow up received on 15-jul-2021. Added patient demographics, relevant history lip herpes, concomitant medication, vaccine batch number and route added and  events start date added