pain and itch; many red spots on the top of both hands and neck to me feel very itch; my two palm and fingers itch; broken skin, gap, dry; broken skin, gap, dry; finger numbness; felt my upper right arm little pain and more and more hard knots; more and more hard knots; some blisters on the both sides and top of tongue; I felt tongue painful; I couldn't sleep in the night; pain and itch; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 63 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 16Jun2021 10:15 (Batch/Lot number: unknown) at the age of 62 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Thyroid cancer" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose Number: 1, Lot No: Unknown. Obscured by other product labelling, Location of injection: Arm Left, Vaccine Administration Time: 10:15 AM), administration date: 26May2021, when the patient was 62 years old, for COVID-19 immunization. The following information was reported: TONGUE BLISTERING (non-serious) with onset Jul2021, outcome "not recovered", described as "some blisters on the both sides and top of tongue"; GLOSSODYNIA (non-serious) with onset Jul2021, outcome "not recovered", described as "I felt tongue painful"; INSOMNIA (non-serious) with onset Jul2021, outcome "not recovered", described as "I couldn't sleep in the night"; PAIN (non-serious) with onset Jul2021, outcome "not recovered", PRURITUS (non-serious) with onset 09Feb2022, outcome "recovering" and all described as "pain and itch"; RASH MACULAR (non-serious) with onset 03Jan2022, outcome "recovered", described as "many red spots on the top of both hands and neck to me feel very itch"; PRURITUS (non-serious) with onset Jul2021, outcome "not recovered", described as "my two palm and fingers itch"; SKIN DISORDER (non-serious), DRY SKIN (non-serious) all with onset Jul2021, outcome "not recovered" and all described as "broken skin, gap, dry"; HYPOAESTHESIA (non-serious) with onset Jul2021, outcome "not recovered", described as "finger numbness"; PAIN IN EXTREMITY (non-serious) with onset Jul2021, outcome "not recovered", described as "felt my upper right arm little pain and more and more hard knots"; MASS (non-serious) with onset Jul2021, outcome "not recovered", described as "more and more hard knots". The events "some blisters on the both sides and top of tongue", "i felt tongue painful", "i couldn't sleep in the night", "pain and itch", "pain and itch", "many red spots on the top of both hands and neck to me feel very itch", "my two palm and fingers itch", "broken skin, gap, dry", "broken skin, gap, dry", "finger numbness", "felt my upper right arm little pain and more and more hard knots" and "more and more hard knots" were evaluated at the physician office visit. Therapeutic measures were taken as a result of tongue blistering, glossodynia, insomnia, pain, pruritus, rash macular, pruritus, skin disorder, dry skin, hypoaesthesia, pain in extremity, mass.  Additional Information-Patient was the first time during her life to find there were some blisters on the both sides and top of tongue when she felt tongue painful since the middle of the Jul2021 after one month my second vaccine shot. So far I have visited all kind of doctors (Family, Allergy & ENT, Neurology, Traditional doctors) many times, they can't stop the pain and let the blisters gone after I took the medicines they provided. I couldn't sleep in the night due to the pain and itch. And had many red spots on the top of both hands and neck to feel very itch since 03Jan2022. After she took medicines about 15day, the spots and itch gone. From 09Feb2022 her two palms and fingers itch, broken skin, gap, dry and finger numbness. This month, she felt her upper right arm little pain and more and more hard knots she could touch soft tissue of the arm, family doctor requested me do ultrasound.Patient was not covid prior vaccination. Patient did not covid tested post vaccination. Known allergies: None  The lot number for bnt162b2 was not provided and will be requested during follow up.