head and brain felt like squeezing; she was nauseous; Fever/her under arm reading, she is usually 92 or 94 and it was 100 and it was persistent for 48 hours or more; gets a headache/ had this horrible headache; Anywhere she touched herself, her skin hurt, all her skin hurt; shot went in lower on her arm; Extremely painful as soon as the injection went into her arm; tiny bit of tingling in her hand; arm was pretty swollen; she didn't sleep, she couldn't sleep, she got maybe 2 hours of sleep that night; had pain in calves; hot/cold sweating; chest pain; anywhere it seemed she'd ever had a problem in her whole life seemed to kind of light up, seemed to be inflamed; she ached everywhere; stomach still kind of isn't right, her stomach was bothering her too; had a little bit of a cough; Runny nose; it was to the point where she could not concentrate/she can't remember now; She could barely walk down the steps, she ached everywhere; This is a spontaneous report from a contactable consumer (patient) via Medical Information Team. A 53-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: EW0177), via unspecified route of administration in left arm on 13Jun2021 at 17:30 (53-year-old at vaccination) as a Dose 2, single for COVID-19 immunization. The patient's medical history included ongoing factor V deficiency, which was diagnosed a long time ago, that's concerning to her. The patient's parents both had the Pfizer one back in right as soon as they could and didn't have any problems, and her son got the Moderna, but he was fine. There were no concomitant medications. Historical vaccine included Flu shot, Tetanus shot, and she experienced really painful at the site during tetanus shot. The patient was not related to any study or program. Vaccine was not administered at another facility. The patient was neither administered with any other vaccine on same date of the Pfizer COVID vaccination nor 4 weeks within COVID-vaccination. The patient previously received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: EW0176, expiration date: Unknown) via unspecified route of administration on 23May2021 around 17:30-18:00 in left arm (53-year-old at vaccination) as a Dose 1, single for COVID-19 immunization. After her first dose her arm was sore. After the second shot, her head and brain felt like squeezing, she was nauseous, had pain in calves when she would walk, hot/cold sweating, fever. She continued to have headache and sweats. Her headache was worse before but had improved. The reporter stated that, " her headache was insane." She stated " she was still experiencing headache every single day now, never had that before. It was not right. When it would be gonna go away. She would like to know what was going on with her body. " She was informed by Pfizer to refer to her HCP for medical advice. Since second dose she also had chest pain too but that was not the major thing, she does not know what it was going on with that, but it had been here and there since she had the vaccine. She said the main thing that was happening was the constant headache. She had noticed the chest pain since she had the vaccine it would come and go and she was just though oh yeah because she had it again last night and she did not tell them about that, she clarifies really it was early this morning because she waked up a lot because she was not sleeping well from it and it was like tingling kind of thing, it was not like a gripping kind of thing and then it just went away and it happened here and there and she though well she had that too so maybe she need to let them know that. It was just that everything from the beginning was so intensified by her fever and her brain feeling like it was being squeezed out of her head that the chest pain was not the predominate thing, she did not have like gripping heart pain, it wasn't that strong it was just here and there. It was not that it was so painful. She clarified because of everything else that was going on, she could not exactly tell when the chest pain began because she had been having symptoms since 13Jun2021 she was going on a month of this mess, it came and goes but it's not like she was bent over hurting or she would do something about it, this was just something else she noticed. She stated but then she was getting hot and cold sweats after getting it and a mild headache, she just didn't feel good, she didn't feel really bad just didn't feel good. She stated last March, she thought she had COVID. She stated it kind of had a little similar effect of how she felt back then but nothing to the extreme of what she had when she had that, but she does not know for sure if she had it then because testing wasn't out then. She stated she did have an antibody test in October, and it showed she didn't have any antibodies, but her doctor said that does not really mean anything since nobody really knows anything about it. She stated she was hesitant of getting the second shot because she doesn't want to feel bad the rest of the summer. She stated she ended up getting it. She stated when she got it (second dose), it was extremely painful as soon as the injection went into her arm. She stated she felt like it went in lower on her arm but didn't really thought about it. She stated she wasn't expecting that much of a kick in it. She stated she had a tiny bit of tingling in her hand and that's it. She stated she went to help her parents, she went over there, and she felt fine that night, she got it around 5:30 PM on a Sunday, 13Jun2021 and then that night she was really fine except her arm at the injection site, which normal kind of thing, but it was pretty swollen, but she was expecting that. She stated she did not sleep; she was expecting to sleep. She stated, she couldn't sleep, she got maybe 2 hours of sleep that night. She stated the next day, 14Jun2021, that was when it got really bad. She stated she had a fever and then anywhere she touched herself, her skin hurt, all her skin hurt and then anywhere it seemed she'd ever had a problem in her whole life seemed to kind of light up. She stated if she had TMJ in her face, anywhere she ever had anything, it just seemed to be inflamed. She stated she had this horrible headache, she felt like her brain was going to be squeezed out of her skull, her brain was too big for her skull for 2 days. She stated she though what she should do it. She stated all she could though about was how bad her head hurt. She stated she still had headaches, but nothing to that extreme, she had that for 2 days. She stated then she felt nauseous too that day. She confirmed the next day was when most all of her symptoms occurred on 14Jun2021. She stated she was just tried to reach out to someone she knows who worked at the clinic because she though what in the world was going on with her brain and though was this what she had, she cannot imagine this was what everyone was having, she didn't even want to look at her phonon, answer her phone, it kept her from doing anything, the squeezing of her brain. She stated then she had her calves, it hurt really bad to walk up and down her steps, she only got out of bed one time, she could barely walk down the steps, she ached everywhere. She stated then the hot and cold, her whole body would be soaked then she would be cold. She stated the sweats had been going on since then, every night. She stated ever night, she had not been sleeping. She stated maybe she would get 3 or 4 hours and she gets a headache. She stated its not where near what it was, but she had a headache and she continued with a headache until 1PM then it goes away and then every night its back again, the same thing, the headache every night since then. She stated the headache and sweats are ongoing. She stated the headaches were definitely worse before, she could not even think or function basically. She stated she was starting to wonder if it was a blood clot in her brain. She confirmed the headache had improved. She stated sweats were worse, but they are still were worse, but they are still bad. She stated they are persisting now. She stated she was like when was this ever going to end, this was ridiculous. She stated each week she thought maybe this was going to go away. She stated she knew no one who was having this, anywhere she touched herself, her skin hurt, all her skin hurt. She stated her sheets even hurt her and her clothing hurt her. She stated she does not have that anymore. She stated the other things she still had now was her calves hurt, it was ongoing and persistent. She stated it was worse those few days when she had a really bad headache. She stated she was trying to read about it. She stated it said she should not really take stuff for the fever because it's her body fighting it, so she did not take stuff, she tried to do what it said to do. She stated she never got headaches before this; this was so not like her. She confirmed the nausea began 14Jun2021. She stated her stomach still kind of was not right, her stomach was bothering her too. She stated the worst things now was the headache and sweats, being hot and cold, that's the main thing now, she was never had that before. She confirmed all symptoms after the second dose of the Pfizer COVID 19 Vaccine began in Jun2021. She stated she doesn't though she had a fever, she had a really low body temperature anyway. She stated her under arm reading, she was usually 92 or 94 and it was 100 and it was persistent for 48 hours or more. She stated she does not feel like she had not had the need to check for a fever. She stated it seems like when she did, if she was sweating like in the beginning, but now she does not check it anymore, mainly she was afraid because of the squeezing of her brain. She had this horrible headache, she felt like her brain was going to be squeezed out of her skull. She stated it was still there a little bit, it was to the point where she could not concentrate. She stated she swears her brain was way too big. She stated she still had squeezing, it was not the same now, it was improved. She stated it does not hurt like that anymore, but it was ongoing. She stated she never really had headaches before, so she does not really know how to describe it. She stated now it squeezed at the front toward the front but before it was like it squeezed all over, she does not know how to describe it, there was a pressure on her skull when its being squeezed, but it's not like it was. She stated she didn't really want to receive vaccine but felt like she needed to so she wouldn't get sick but then she just got sick and that's why she didn't want to get it. She stated its real strange to her, like she said, she felt like she had COVID last march, the testing and everything wasn't out back then. She stated oh another thing she had, that night she had a little bit of a cough and a runny nose and she thought where this came from. She stated it was almost like an escalated version of having COVID. She confirmed it was on 14Jun2021 that night or the next night, she can't remember now. She stated her nose started running a little bit and was having a little bit of a cough, but it was very short lived- recovered completely and ended in Jun2021. She stated she had a long cough in March, that thing lasted forever, but this was really tiny. She stated she stayed in bed for almost 2 weeks, she doesn't exactly know how long now, it was a while before she felt right, now she continued to do things. The reported stated that adverse events did not resulted to visit emergency room/physician office. She stated that, she only probably slept 2 hours a night for the first whole week that time in Jun2021 because her head was killing her, and it wouldn't let her sleep. She stated trouble sleeping was still ongoing, it's gotten better, it's improved, but it's still not good. The outcome of the events head/brain felt like squeezing, couldn't sleep, headache was recovering, pain in calves, hot/cold sweating was not recovered, and cough, runny nose was recovered on Jun2021 and outcome of other events was unknown.