Grip strength decreased/dropping things lately; Mobility decreased/difficulty out of bed/ opening car doors; Joint range of motion decreased/difficulty reaching above head to get down 5 lb object; Reduced general condition; Sweating; low antibodies after covid vaccinations and booster/Immunoglobulins decreased; Pain; Chills; This spontaneous case was reported by a consumer and describes the occurrence of ASTHENIA (Grip strength decreased/dropping things lately), MOBILITY DECREASED (Mobility decreased/difficulty out of bed/ opening car doors), JOINT RANGE OF MOTION DECREASED (Joint range of motion decreased/difficulty reaching above head to get down 5 lb object), GENERAL PHYSICAL HEALTH DETERIORATION (Reduced general condition) and HYPERHIDROSIS (Sweating) in an adult female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) solution for injection for Rheumatoid arthritis and Psoriatic arthritis.    The patient's past medical history included Activities of daily living impaired (difficulty in cutting meat/lifting a full cup to her mouth and dressing herself/ doing chores, difficulty out of bed/opening car doors and difficulty reaching above head to get down 5 lb object.). Concurrent medical conditions included Rheumatoid arthritis (moderate to severe rheumatoid arthritis) and Psoriatic arthritis.   On 02-Aug-2021, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) 40 milligram every two weeks. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced ASTHENIA (Grip strength decreased/dropping things lately), MOBILITY DECREASED (Mobility decreased/difficulty out of bed/ opening car doors), JOINT RANGE OF MOTION DECREASED (Joint range of motion decreased/difficulty reaching above head to get down 5 lb object), GENERAL PHYSICAL HEALTH DETERIORATION (Reduced general condition), HYPERHIDROSIS (Sweating), IMMUNOGLOBULINS DECREASED (low antibodies after covid vaccinations and booster/Immunoglobulins decreased), PAIN (Pain) and CHILLS (Chills). At the time of the report, ASTHENIA (Grip strength decreased/dropping things lately), GENERAL PHYSICAL HEALTH DETERIORATION (Reduced general condition), HYPERHIDROSIS (Sweating), PAIN (Pain) and CHILLS (Chills) outcome was unknown and MOBILITY DECREASED (Mobility decreased/difficulty out of bed/ opening car doors), JOINT RANGE OF MOTION DECREASED (Joint range of motion decreased/difficulty reaching above head to get down 5 lb object) and IMMUNOGLOBULINS DECREASED (low antibodies after covid vaccinations and booster/Immunoglobulins decreased) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Grip strength: decreased. On an unknown date, Immunoglobulins: decreased. On an unknown date, Pain assessment: Increased from 7 to 60/100.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       No concomitant medications were reported.  On an unknown date, health score was increased from 2 to 33/100.  No treatment details were reported.  The outcome for the events Mobility decreased and Joint range of motion decreased was reported as Worsened.  The reporter's causality for Humira 40mg/0.4ml(adalimumab) for the event(s) of low antibodies after covid vaccinations and booster, chills, dropping things lately, difficulty out of bed/ opening car doors, difficulty reaching above head to get down 5 lb object, health score increased from 2 to 33/100, sweats and pain was not provided. As   This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.   Reporter did not allow further contact