blood clotting; Almost paralyzed; severe Headaches; blurry vision; Whole body on fire; No taste; No smell; Heart palpitations; Excessive sweating; My TH3, liver elevated; My TH3, liver elevated; My blood pressure started being very low; blood pressure now extremely high like 190.115; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 61-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 08Aug2022 at 12:00 as dose 4 (booster), single (Lot number: EL0142) at the age of 61 years, in right arm for covid-19 immunisation; varicella zoster vaccine rge (cho) (SHINGRIX), on 08Aug2022 as dose 2, single (Batch/Lot number: unknown) for immunisation; influenza vaccine (FLU VACCINE VII), on 08Aug2022 as dose 1, single (Batch/Lot number: unknown) for immunisation. The patient's relevant medical history included: "Migraine" (unspecified if ongoing); "fibromyalgia" (unspecified if ongoing); "depression" (unspecified if ongoing); "heart disease" (unspecified if ongoing). Concomitant medication(s) included: ASPIRIN (E.C.); METOPROLOL; ATORVASTATIN; HYDROCODONE; SERTRA. Past drug history included: Z-pack, reaction(s): "Known allergies: Z-pack"; Known allergies: metformin, reaction(s): "Known allergies: metformin"; Known allergies: topiramate, reaction(s): "Known allergies: topiramate"; Known allergies: oxycodone, reaction(s): "Known allergies: oxycodone". Vaccination history included: shingles/shingrix (Dose 1, Single), administration date: 11Jan2022, for Immunisation; Covid-19 vaccine (DOSE 1; MANUFACTURER UNKNOWN), for COVID-19 immunisation; Covid-19 vaccine (DOSE 2; MANUFACTURER UNKNOWN), for COVID-19 immunisation; Covid-19 vaccine (DOSE 3 (BOOSTER); MANUFACTURER UNKNOWN), for COVID-19 immunisation. The following information was reported: HYPERTENSION (life threatening) with onset 08Aug2022, outcome "not recovered", described as "blood pressure now extremely high like 190.115"; PARALYSIS (medically significant, life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "Almost paralyzed"; HYPERHIDROSIS (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "Excessive sweating"; PALPITATIONS (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "Heart palpitations"; TRI-IODOTHYRONINE INCREASED (life threatening), HEPATIC ENZYME INCREASED (life threatening) all with onset 08Aug2022 at 16:45, outcome "not recovered" and all described as "My TH3, liver elevated"; HYPOTENSION (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "My blood pressure started being very low"; ANOSMIA (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "No smell"; AGEUSIA (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "No taste"; FEELING HOT (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "Whole body on fire"; THROMBOSIS (medically significant, life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "blood clotting"; VISION BLURRED (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "blurry vision"; HEADACHE (life threatening) with onset 08Aug2022 at 16:45, outcome "not recovered", described as "severe Headaches". The events "blood clotting", "almost paralyzed", "severe headaches", "blurry vision", "whole body on fire", "no taste", "no smell", "heart palpitations", "excessive sweating", "my th3, liver elevated", "my blood pressure started being very low" and "blood pressure now extremely high like 190.115" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (08Aug2022) started being very low; (08Aug2022) 190.115, notes: extremely high like 190.115; Hepatic enzyme: (08Aug2022) liver elevated; Smear test: (01Feb2023) Negative; (16Mar2023) Negative; (21Apr2023) Negative; Tri-iodothyronine: (08Aug2022) TH3 elevated. Therapeutic measures were not taken as a result of thrombosis, paralysis, headache, vision blurred, feeling hot, ageusia, anosmia, palpitations, hyperhidrosis, tri-iodothyronine increased, hepatic enzyme increased, hypotension, hypertension. Clinical course: Heart and lungs, kidneys, liver, eyes, severe Headaches, blurry vision, blood clotting. Whole body on fire, felt like something was attacking her insides her eardrums and face and spine on fire. It was so severe. No taste or smell. swallowing stomach. Heart palpitations. Excessive sweating. Her immediate system was being attacked., Her TH3, liver elevated. Her blood pressure started being very low, but now extremely high like 190.115. Almost paralyzed. No one was doing anything. She had been to the Emergency Room about 6 times. Sent her right back home with no type of treatment. 08Aug2023 makes a year that she been suffering. After while she no that she was not going to be living. No one was listening to her. Doctor or other healthcare professional office/clinic visit, Emergency room/department or urgent care, Life threatening illness (immediate risk of death from the event).