sudden feeling of being very unwell that felt like potential heart attack symptoms; sudden feeling of being very unwell that felt like potential heart attack symptoms; extreme fatigue and sudden shortness of breath/shortness of breath while walking; chest tightness; nausea; headache; Flu-like symptoms and greater fatigue; unusual heart PVC's started and worsened over the next 6 days; unusual heart PVC's started and worsened over the next 6 days; feeling very tired that was not cured by sleeping; moderate muscle pain and aches; moderate muscle pain and aches; This is a spontaneous report from a contactable consumer (patient). A female patient of an unspecified age received the 2nd dose of bnt162b2 (BNT162B2, Manufacturer Pfizer-BioNTech), via an unspecified route of administration in arm left, on 20Apr2021 at 08:30 AM (Lot Number: ER8732), as single dose, for COVID-19 immunisation. Medical history included atrial fibrillation corrected by cardiac ablation, drug hypersensitivity (all sulfur related drugs). Concomitant medication included alprazolam (unknown manufacturer). Previously the patient received the 1st dose of bnt162b2 (BNT162B2, Manufacturer Pfizer-BioNTech, lot# ER8732) for COVID-19 immunisation, at single dose in arm left, on 30Mar2021 at 08:15 AM. The patient experienced sudden feeling of being very unwell that felt like potential heart attack symptoms (medically significant) on 27Apr2021 with outcome of recovering, moderate muscle pain and aches (non-serious) on 20Apr2021 with outcome of recovering, unusual heart pvc's started and worsened over the next 6 days (non-serious) on 22Apr2021 with outcome of recovering, feeling very tired that was not cured by sleeping (non-serious) on 22Apr2021 with outcome of recovering, flu-like symptoms and greater fatigue (non-serious) on 26Apr2021 with outcome of recovering, extreme fatigue and sudden shortness of breath/shortness of breath while walking (non-serious) on 27Apr2021 with outcome of recovering, chest tightness (non-serious) on 27Apr2021 with outcome of recovering, nausea (non-serious) on 27Apr2021 with outcome of recovering, headache (non-serious) on 27Apr2021 with outcome of recovering. The events required emergency room visit. On unknown date the patient underwent lab tests and procedures which included blood test: unknown result, chest x-ray: unknown result, electrocardiogram: unknown result. Therapeutic measures were taken as a result of the events. Clinical course: beginning later the same day after receiving 2nd vaccine dose and continuing for 2 days, moderate muscle pain and aches. On 22Apr2021 unusual heart PVC's started and worsened over the next 6 days. Also beginning at that time, feeling very tired that was not cured by sleeping.  On 26Apr2021, began feeling flu-like symptoms and greater fatigue. On 27Apr2021, extreme fatigue and sudden shortness of breath while walking from my car to the office, accompanied by chest tightness, nausea, headache, intense, and sudden feeling of being very unwell that felt like potential heart attack symptoms. These continued throughout the day. On 28Apr2021, continued fatigue and all other symptoms including the heart PVC's. All symptoms began to lessen near the end of the day. On 29Apr2021, further lessening of all symptoms. Prior to vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient has not been tested for COVID-19.