uveitis; viral keratitis; floaters in my vision field; scleritis in the right eye/ scleritis; cornea ulceration in her right eye. It was so bad that it was radiating to her left side; This spontaneous case was reported by a consumer and describes the occurrence of ULCERATIVE KERATITIS (cornea ulceration in her right eye. It was so bad that it was radiating to her left side), UVEITIS (uveitis), SCLERITIS (scleritis in the right eye/ scleritis), KERATITIS VIRAL (viral keratitis) and VITREOUS FLOATERS (floaters in my vision field) in a 46-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 065F21A) for COVID-19 vaccination.     The patient's past medical history included COVID-19 on 31-Dec-2020 and COVID-19 on 20-Dec-2021. Previously administered products included for COVID-19 vaccination: PFIZER BIONTECH COVID-19 VACCINE (Dose Number: 1, Lot number: EK5730.) on 21-Dec-2020, PFIZER BIONTECH COVID-19 VACCINE (Dose Number: 2 and Lot number: EK9231.) on 01-Feb-2021. Past adverse reactions to the above products included No adverse reaction with PFIZER BIONTECH COVID-19 VACCINE and PFIZER BIONTECH COVID-19 VACCINE. Concurrent medical conditions included Drug allergy (Floxin allergy), Penicillin allergy, Allergy to antibiotic (Levaquin allergy) and Drug allergy (Droperidol allergy).    On 03-Feb-2022, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 07-Feb-2022, the patient experienced ULCERATIVE KERATITIS (cornea ulceration in her right eye. It was so bad that it was radiating to her left side) (seriousness criterion medically significant). On 11-Feb-2022, the patient experienced SCLERITIS (scleritis in the right eye/ scleritis) (seriousness criterion medically significant) and VITREOUS FLOATERS (floaters in my vision field) (seriousness criterion medically significant). On 15-Feb-2022, the patient experienced UVEITIS (uveitis) (seriousness criterion medically significant) and KERATITIS VIRAL (viral keratitis) (seriousness criterion medically significant). The patient was treated with TOBRAMYCIN from 07-Feb-2022 to 15-Feb-2022 at a dose of UNK, every hour; VANCOMYCIN from 07-Feb-2022 to 15-Feb-2022 at a dose of UNK, evry hour; NAPROXEN for Inflammation, at a dose of 500 milligram twice a day; OMEPRAZOLE for Stomach function disorder, at a dose of 20 milligram once a day; CYCLOPENTOLATE from 16-Feb-2022 to 18-Feb-2022 at a dose of cyclopentolate 1% three times a day for 3 days; POLYMYXIN B SULFATE, TRIMETHOPRIM (POLYMYXIN B -TRIMETHOPRIM OPHTHA.) at a dose of four times a day; PREDNISOLONE ACETATE (PREDNISOLON [PREDNISOLONE ACETATE]) at a dose of prednisolone AC 1% four times a day and VALACICLOVIR HYDROCHLORIDE (VALTREX) at a dose of 500 milligram twice a day. At the time of the report, ULCERATIVE KERATITIS (cornea ulceration in her right eye. It was so bad that it was radiating to her left side), UVEITIS (uveitis), SCLERITIS (scleritis in the right eye/ scleritis), KERATITIS VIRAL (viral keratitis) and VITREOUS FLOATERS (floaters in my vision field) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered ULCERATIVE KERATITIS (cornea ulceration in her right eye. It was so bad that it was radiating to her left side) to be not related. No further causality assessments were provided for UVEITIS (uveitis), SCLERITIS (scleritis in the right eye/ scleritis), KERATITIS VIRAL (viral keratitis) and VITREOUS FLOATERS (floaters in my vision field).    The light really bothers patients eyes. That continued until 06Feb2022. On 07Feb2022, she had such excruciating head pain that was from her right eye going into her right forehead and her temple. It affected the right side of her head. Her eye pain was so bad on the right side that she went to be evaluated at the emergency room. Patient was found originally with a cornea ulceration in her right eye. It was so bad that it was radiating to her left side. They told her that her left eye was ok. She had to take special eye drops (Tobramycin and vancomycin) every hour. They didn't think it was related to the booster.  Patient had a new pain in the corner of her right eye near her nose. They did an exam but didn't see anything. She started using her eye drops (Tobramycin and vancomycin) every 2 hours. On Thursday 10Feb2022, the right eye became red and really painful. Patient was still having the head pain on the right side of her head. On Friday 11Feb2022, Patient was having visual changes and floaters in her vision field. Patient had to return to the emergency room. Patient was told to decrease the eye drops to every 3 hours until 13Feb2022, and then switched to four times a day thereafter. The doctor said that there was so much inflammation in her eye that she felt like this was an inflammation response. The doctor stated that there was immune concern following the COVID19 vaccination. Then she stopped tobramycin and vancomycin.  Company comment- This spontaneous case concerns a 46-year-old, female patient with relevant medical history of Covid 19 and allergy to various drugs and with interchange of vaccine products (Tozinameran, pfizer biontech covid-19 vaccine), who experienced serious unexpected events of Ulcerative keratitis (after 4 days), Scleritis (after 8 days), Vitreous floaters(8 days), Uveitis (after 12 days) and Viral keratitis (after 12 days) after receiving booster dose of mRNA-1273 Vaccine. The doctor stated that there was immune concern following the COVID19 vaccination. Medical history of Covid 19 and allergy to medications could be a risk factor for the event uveitis. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a 46-year-old, female patient with relevant medical history of Covid 19 and allergy to various drugs and with interchange of vaccine products (Tozinameran, pfizer biontech covid-19 vaccine), who experienced serious unexpected events of Ulcerative keratitis (after 4 days), Scleritis (after 8 days), Vitreous floaters(8 days), Uveitis (after 12 days) and Viral keratitis (after 12 days) after receiving booster dose of mRNA-1273 Vaccine. The doctor stated that there was immune concern following the COVID19 vaccination. Medical history of Covid 19 and allergy to medications could be a risk factor for the event uveitis. The benefit-risk relationship of mRNA-1273 is not affected by this report.