it felt like she was going to die/not feeling great; blood pressure is high, diastolic blood pressure was up to 161; This is spontaneous report from contactable consumer (patient). This 49-year-old female patient received the second dose of bnt162b2 (BNT162B2), via an unspecified route of administration, administered in right arm on 23Apr2021 11:00 (Batch/Lot Number: ER8731) as single dose for Covid-19 vaccine. Medical history included problems with intestines 8 years before, high blood pressure in 2008 or 2009 with diastolic blood pressure usually goes no higher than 109, acid reflux in 2002 or 2003, all ongoing, 13 surgeries including one for a brain aneurysm. Concomitant medications included amlodipine for blood pressure measurement from an unspecified start date to 27Apr2021; hyoscyamine for problems with intestines and ongoing; ondansetron hydrochloride (ZOFRAN) for stomach and ongoing; esomeprazole sodium (NEXIUM) for acid reflux and ongoing. She had no side effects from the first dose of the Pfizer Covid-19 vaccine Injection on 02Apr2021 (Lot Number EP7533) on Right arm for Covid-19 vaccine. She ended up having a pretty bad reaction to the Covid-19 vaccine. The following day after receiving the Covid-19 vaccine, on 24Apr2021, she started not feeling great. Her blood pressure was high, but the lower number usually doesn't go higher than 109. The patient reported that her diastolic blood pressure was up to 161 on 24Apr2021. Pfizer Covid-19 vaccine made her blood pressure go through the roof on 24Apr2021 where they were afraid that she was going to have a stroke or heart attack. The patient was in hospital for blood pressure was through the roof from 26Apr2021 to 27Apr2021. Her blood pressure going through the roof made her felt like she was going to die. She was on amlodipine 2.5 mg and because her blood pressure got so high they adjusted it to 10 mg. Her physician prescribed her Lisinopril 40 mg once daily. Her physician called in the lisinopril 40 mg to the pharmacy when increased patient's dosage of amlodipine from 2.5 mg to 10 mg. Her physician informed her that the Amlodipine takes a week to be effective. She was given lisinopril in the emergency room and that lisinopril is faster acting to lower blood pressure. The patient was now taking both Amlodipine 10 mg and Lisinopril 40 mg once daily in the morning and knock on wood she's been doing fine. Lisinopril did not lower her blood pressure and she had to go back to the emergency room. She ended up having to get beta blockers, meclizine, and lorazepam. All 3 of the medications work together to keep her blood pressure down. Her physician informed her that she should have already gone to the hospital and prescribed an additional high blood pressure medication. The patient reported that the new blood pressure medication didn't work so she went to the emergency room on 26Apr2021. Her blood pressure returned to normal on 07May2021 or 08May2021. Blood pressure spiked on 24Apr2021 and she felt like she was going to die required a visit to emergency room. The patient reported that she went to the emergency room three times. She went to the emergency room on 26Apr2021 and was kept overnight until 27Apr2021. She had to go back to the emergency room on 27Apr2021, after she was discharged. The patient also reported that she went to the emergency room the third time on 28Apr2021. The emergency room staff performed brain tests, X-rays, CT scans, MRIs in Apr2021, and couldn't find any reason for the patient's blood pressure to be elevated. The physicians at the emergency room were assuming that the Pfizer Covid-19 vaccine is what caused the caller's elevated blood pressure because that was the only thing that was different. They performed tons of blood work in Apr2021 while she was in the emergency room and it all came back normal. CT scan abdomen, brain, and chest without contrast on 26Apr2021 and on 27Apr2021, X-ray on 26Apr2021 are all normal. The outcome of blood pressure is high was recovered in May2021. The outcome of other event was unknown