Pain all over her body after 2nd dose; Freezing after 2nd dose; Earache after 2nd dose; 3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose; 3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose; 3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose; 3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose; 3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose; Pain in the injection site after 2nd dose; Very tired after 2nd dose; Fever after 2nd dose( not measured); Headache after 2nd dose; Little sore after 1st dose; Little tired after 1st dose; This spontaneous case was reported by a patient and describes the occurrence of PAIN (Little sore after 1st dose), PAIN (Pain all over her body after 2nd dose), FREEZING PHENOMENON (Freezing after 2nd dose), EAR PAIN (Earache after 2nd dose) and ERYTHEMA (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 006B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included ADHD. Concomitant products included LISDEXAMFETAMINE MESILATE (VYVANSE) for an unknown indication.    On 09-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 09-Apr-2021, the patient experienced PAIN (Little sore after 1st dose) and FATIGUE (Little tired after 1st dose). On an unknown date, the patient experienced PAIN (Pain all over her body after 2nd dose), FREEZING PHENOMENON (Freezing after 2nd dose), EAR PAIN (Earache after 2nd dose), ERYTHEMA (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), FEELING HOT (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PERIPHERAL SWELLING (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PRURITUS (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PAIN IN EXTREMITY (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), INJECTION SITE PAIN (Pain in the injection site after 2nd dose), FATIGUE (Very tired after 2nd dose), PYREXIA (Fever after 2nd dose( not measured)) and HEADACHE (Headache after 2nd dose). The patient was treated with FEXOFENADINE HYDROCHLORIDE, PSEUDOEPHEDRINE HYDROCHLORIDE (ALLEGRA D) at an unspecified dose and frequency and IBUPROFEN (ADVIL [IBUPROFEN]) at an unspecified dose and frequency. At the time of the report, PAIN (Little sore after 1st dose), PAIN (Pain all over her body after 2nd dose), FREEZING PHENOMENON (Freezing after 2nd dose), EAR PAIN (Earache after 2nd dose), ERYTHEMA (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), FEELING HOT (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PERIPHERAL SWELLING (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PRURITUS (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), PAIN IN EXTREMITY (3 very large red circles, super hot, itchy, swollen, orange sized circles, that hurts and stinks in her legs after 2nd dose), INJECTION SITE PAIN (Pain in the injection site after 2nd dose), FATIGUE (Very tired after 2nd dose), PYREXIA (Fever after 2nd dose( not measured)), FATIGUE (Little tired after 1st dose) and HEADACHE (Headache after 2nd dose) outcome was unknown.