the red rash and hives maybe cellulitis; a red rash with hives at the COVID-19 Vaccine injection site; a red rash with hives at the COVID-19 Vaccine injection site; she felt red and itchy and noticed swelling at the injection site/ a red rash with hives at the COVID-19 Vaccine injection site; she felt red and itchy and noticed swelling at the injection site; she felt red and itchy and noticed swelling at the injection site/ a red rash with hives at the COVID-19 Vaccine injection site; she had experienced a red rash and hives at the vaccine injection site because the vaccine was administered at an incorrect location on her arm; arms soreness; This is a spontaneous report from a contactable nurse (patient). A 35-year-old female patient received the first dose of bnt162b2 (Pfizer-Biontech COVID-19 Vaccine, Lot number: Unknown), via an unspecified route of administration at the right deltoid on 23Jan2021 11:30 at a single dose for COVID-19 immunization. The vaccine was administered in a hospital; not in a military facility. Medical history included ongoing eczema since infant and childhood asthma. Her childhood asthma was exercised induced. She stated she has not had an occurrence of asthma since she was 10 years old. There were no concomitant medications. Felt fine, just had the normal arms soreness on Jan2021. But reports that around 36 hours later, she felt red and itchy and noticed swelling at the injection site on 24Jan2021. Reported on 24Jan2021 at about 6:00PM she developed a red rash with hives at the COVID-19 Vaccine injection site. She said she was trying to do research to see if what she was experiencing was an expected side effect of the COVID-19 Vaccine, and if so, how to treat the red rash and hives. She said she put a cold compress on the injection site and took Motrin. She said the injection site red rash with hives subsided. She said later on the night of 24Jan2021, at 11:00PM, the red rash and hives at the COVID-19 Vaccine injection site started up again. She reports that she took Benadryl and Motrin and applied some Cortisone cream. The red rash and hives subsided. She said last night, 25Jan2021, the red rash and hives happened again at the COVID-19 Vaccine injection site. She said the red rash and hives seems to only happen at night. She said she thought her COVID-19 Vaccine dose was administered a bit low on her arm. She said she thought maybe she had experienced a red rash and hives at the vaccine injection site because the vaccine was administered at an incorrect location on her arm. She said she felt fine after receiving the COVID-19 Vaccine and thought the red rash and hives maybe cellulitis. She said her throat was fine, and during the day the COVID-19 Vaccine injection site was fine. She said the red rash and hives at the COVID-19 Vaccine inject site only starts again at night. The events did not require Emergency Room nor No Physician Office visit. The patient has not received any other vaccines within 4 weeks prior to the COVID vaccine. The outcome of the event arm soreness was unknown and for the events she felt red and itchy and noticed swelling at the injection site/ a red rash with hives at the COVID-19 Vaccine injection site and the red rash and hives maybe cellulitis was recovering.   Information about lot/batch number has been requested.