Causing the inability to do normal daily activities; lLoss of feeling to my fingers; Muscles in her arms atrophy; She can't grip with her hands/ lost the ability to grip or to feel anything; Neurological problem; Has a hard time to brush her hair and teeth; constant  shock  sensations  in  both  hands; During the night sometimes her joints hurt and when she wakes up/pain progressed to my shoulder; nerve  blocks  in  my  shouulders  and  fingers; MRI  of  shoulder  showed  inflammation  &  fluid  in  bursa; Autoinflammatory response to the vaccine/acute  inflammatory  or  autoimmune  response; Still experiencing pain; A lot of pain that started in her hands/A lot of pain in her upper arm/biceps area; This spontaneous case was reported by a consumer and describes the occurrence of VACCINATION COMPLICATION (Autoinflammatory response to the vaccine/acute  inflammatory  or  autoimmune  response), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (Causing the inability to do normal daily activities), HYPOAESTHESIA (lLoss of feeling to my fingers), PAIN (Still experiencing pain) and PAIN IN EXTREMITY (A lot of pain that started in her hands/A lot of pain in her upper arm/biceps area) in a 76-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 001A21A and 042L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Concomitant products included MELOXICAM (MOBIC) for Inflammation, ESTRADIOL (ESTRADIOL TRANSDERMAL SYSTEM) for Menopause, GABAPENTIN (NEURONTIN) and IBUPROFEN (ADVIL [IBUPROFEN]) for Nerve pain, LIDOCAINE for an unknown indication.   On 21-Jan-2021 at 11:21 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 25-Feb-2021 at 3:05 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In February 2021, the patient experienced PAIN (Still experiencing pain) and PAIN IN EXTREMITY (A lot of pain that started in her hands/A lot of pain in her upper arm/biceps area). On 26-Mar-2021, the patient experienced VACCINATION COMPLICATION (Autoinflammatory response to the vaccine/acute  inflammatory  or  autoimmune  response). On 02-Apr-2021, the patient experienced BURSITIS (MRI  of  shoulder  showed  inflammation  &  fluid  in  bursa). On 13-Jul-2021, the patient experienced NERVE BLOCK (nerve  blocks  in  my  shouulders  and  fingers). On an unknown date, the patient experienced LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (Causing the inability to do normal daily activities), HYPOAESTHESIA (lLoss of feeling to my fingers), MUSCLE ATROPHY (Muscles in her arms atrophy), GRIP STRENGTH DECREASED (She can't grip with her hands/ lost the ability to grip or to feel anything), NERVOUS SYSTEM DISORDER (Neurological problem), MUSCULAR WEAKNESS (Has a hard time to brush her hair and teeth), ELECTRIC SHOCK SENSATION (constant  shock  sensations  in  both  hands) and ARTHRALGIA (During the night sometimes her joints hurt and when she wakes up/pain progressed to my shoulder). The patient was treated with CORTISONE at an unspecified dose and frequency. At the time of the report, VACCINATION COMPLICATION (Autoinflammatory response to the vaccine/acute  inflammatory  or  autoimmune  response), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (Causing the inability to do normal daily activities), HYPOAESTHESIA (lLoss of feeling to my fingers), PAIN (Still experiencing pain), PAIN IN EXTREMITY (A lot of pain that started in her hands/A lot of pain in her upper arm/biceps area), MUSCLE ATROPHY (Muscles in her arms atrophy), GRIP STRENGTH DECREASED (She can't grip with her hands/ lost the ability to grip or to feel anything), NERVOUS SYSTEM DISORDER (Neurological problem), MUSCULAR WEAKNESS (Has a hard time to brush her hair and teeth) and ARTHRALGIA (During the night sometimes her joints hurt and when she wakes up/pain progressed to my shoulder) had not resolved and BURSITIS (MRI  of  shoulder  showed  inflammation  &  fluid  in  bursa), ELECTRIC SHOCK SENSATION (constant  shock  sensations  in  both  hands) and NERVE BLOCK (nerve  blocks  in  my  shouulders  and  fingers) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In March 2021, Laboratory test: ruled  out  rheumatoid  arthritist  but  diagnosed (abnormal) ruled  out  rheumatoid  arthritist  but  diagnosed  as  acute  inflammatory  or  autoimmune  response.. On 02-Apr-2021, Magnetic resonance imaging: showed  inflammation  &  fluid in bursa (abnormal) showed  inflammation  &  fluid in bursa. On 29-Jun-2021, Nerve conduction studies: severe  results (abnormal) severe  results.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   The patient stated that she received first dose of Moderna vaccine on January 21st and had inflammation and burning in my hands. The patient received second dose on 25 Feb 2021, after which her condition progressed to her upper arms and more severe pain in both hands.  The patient stated that she had subsequently visited 7 different doctors for a diagnosis followed by 2 MRIs.  May:17 Cervical, April:2  MRI  of  shoulder showed  inflammation  &  fluid in bursa  The patient stated that she received several injections of cortisone in both hands and shoulder.  The patient stated that she went to an intervention Neurologist for special nerve blocks on July 21st and still have pain and the loss of feeling to my fingers, causing the inability to do normal daily activities.  The patient stated that it has been 8 months and she still has the same reactions and no diagnosis.  Patient lab included May 14: to  Nurse Practitioner, (NAME) requested  lab work.   This case was linked to MOD-2021-294691.   Most recent FOLLOW-UP information incorporated above includes: On 23-Aug-2021: Patient information included. New events- Muscle atrophy, grip strength decreased, neurological symptom, arthralgia, asthenia included. Concomitant medications included. On 25-Aug-2021: Significant Follow up appended-adr form received, events added,concomitant added