Psoriatic arthritis got worse; Sharp increase in her blood pressure; This case was received via an unknown source (no reference has been entered for a health authority or license partner) on 27-Dec-2021 and was forwarded to Moderna on 27-Dec-2021.    This spontaneous case was reported by a consumer and describes the occurrence of PSORIATIC ARTHROPATHY (Psoriatic arthritis got worse) and BLOOD PRESSURE INCREASED (Sharp increase in her blood pressure) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Psoriatic arthritis.    On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced PSORIATIC ARTHROPATHY (Psoriatic arthritis got worse) and BLOOD PRESSURE INCREASED (Sharp increase in her blood pressure). At the time of the report, PSORIATIC ARTHROPATHY (Psoriatic arthritis got worse) and BLOOD PRESSURE INCREASED (Sharp increase in her blood pressure) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: sharp increase (High) Sharp increase.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       Treatment information was not provided. List of concomitant medication were not given. Patient stated that her Psoriatic arthritis got worse and she had sharp increase in her blood pressure after receiving the COVID 19 vaccine.   Company comment: This spontaneous case concerns a female patient of an unknown age with a relevant medical history of Psoriatic arthritis, who experienced the unexpected non serious event of Psoriatic arthritis after mRNA- 1273 vaccine. The event occurred on an unknown date after the dose of mRNA- 1273 vaccine, dose number unknown. Very limited information is available regarding diagnostic work-up, clinical course and treatment prescribed. Psoriatic arthritis was automatically upgraded as serious as per IME list. However, based on information available, the is no evidence to support a medically significant event from a regulatory or clinical standpoint, so it was assessed as non-serious. Previous history of Psoriatic arthritis  remains a confounder. The benefit-risk relationship of mRNA- 1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a female patient of an unknown age with a relevant medical history of Psoriatic arthritis, who experienced the unexpected non serious event of Psoriatic arthritis after mRNA- 1273 vaccine. The event occurred on an unknown date after the dose of mRNA- 1273 vaccine, dose number unknown. Very limited information is available regarding diagnostic work-up, clinical course and treatment prescribed. Psoriatic arthritis was automatically upgraded as serious as per IME list. However, based on information available, the is no evidence to support a medically significant event from a regulatory or clinical standpoint, so it was assessed as non-serious. Previous history of Psoriatic arthritis  remains a confounder. The benefit-risk relationship of mRNA- 1273 vaccine is not affected by this report.