difficulty of breathing; 5th shot of the Pfizer BioNTech covid-19 Vaccine; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. A 79-year-old female patient received BNT162b2 (BNT162B2), on 07Apr2022 as dose 5 (booster), single (Lot number: FK9894) at the age of 79 years for covid-19 immunisation. Relevant medical history included: "COPD" (unspecified if ongoing), notes: COPD Diagnosed before receiving Covid-19 vaccines. There were no concomitant medications. Vaccination history included: Bnt162b2 (DOSE, 1 SINGLE, NDC: Unknown, Lot: Unknown, Expiration: Unknown), for COVID-19 immunization; Bnt162b2 (DOSE, 2 SINGLE, NDC: Unknown, Lot: Unknown, Expiration: Unknown), for COVID-19 immunization; Bnt162b2 (DOSE 3 (BOOSTER), SINGLE, NDC: Unknown, Lot: Unknown, Expiration: Unknown), for COVID-19 immunization; Bnt162b2 (DOSE 4 (BOOSTER), SINGLE, NDC: Unknown, Lot: Unknown, Expiration: Unknown), for COVID-19 immunization.  The following information was reported: INCORRECT DOSE ADMINISTERED (non-serious) with onset 07Apr2022, outcome "unknown", described as "5th shot of the Pfizer BioNTech covid-19 Vaccine"; DYSPNOEA (hospitalization) with onset Apr2022, outcome "unknown", described as "difficulty of breathing". The patient was hospitalized for dyspnoea (hospitalization duration: 5 day(s)). The event "difficulty of breathing" required physician office visit. The patient underwent the following laboratory tests and procedures: Test: (2022) Checked her heart and lungs. Therapeutic measures were taken as a result of dyspnoea with nebulizer, steroids, and oxygen. Clinical course: Caller stated that his wife got the 5th shot of the Pfizer BioNTech Covid-19 Vaccine last 07Apr2022 and stated after a few days, she started to have problems breathing. She went to the pulmonologist to find out if it was caused by the vaccine shot or "part of the problem". After a few days, she went to the hospital and she was there for 5 days and they did every test he could think of to see why she was having difficulty breathing and they couldn't come up with an answer to her condition and they put her on steroids (initially 40mg then changed to 20mg) but she never stops having problems with breathing. It only helped her for a couple of weeks and she was still experiencing difficulty of breathing. Caller stated that he himself got the same shot of the Pfizer Biontech covid-1 vaccine but did not experience the sane side effect with his wife. The patient got all 5 doses of the Pfizer BioNtech covid-19 Vaccine (3rd booster shot). Caller said checked for everything in the hospital and can't find anything and he doesn't know what it was. The only coincidence was after receiving the shot and her breathing kept getting worse. He said he was not saying it was because of the vaccine. He said he was waiting for her doctor to call and if doctor calls he will have to hang up. He said event started the 6th or 7th day after receiving the vaccine. She has been on oxygen since she got home from the hospital. He said oxygen doesn't help and she can walk 10 feet and then she has to sit down and the oxygen doesn't work. He said she can't taste and she is a good cook and it's affecting other part. He said she was on prednisone. He said she has been home for a couple weeks. He asked his wife and she said she has been home for 7 days home from the hospital. He said patient was not real skinny and not real fat and was probably 5' 7" height. They stopped going anywhere since Covid. He said he was calling to see if other people are having problems and if connected to shot? No additional Vaccines Administered on Same Date of the Pfizer Suspect. No prior Vaccinations(within 4 weeks) were received. No family Medical History Relevant to AE(s).  Follow-up attempts are completed. No further information is expected.