suspected covid-19 infection; suspected covid-19 infection; cancer; cancer into overdrive, 3 new cancers; revaccination with different covid-19 vaccine; patient died from unknown cause of death; This is a spontaneous report received from non-contactable reporter(s) (Consumer or other non HCP). Other Case identifier(s): 20230745227 (JANSSEN).  An adult male patient received BNT162b2 (BNT162B2), as dose 2 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation; coviD-19 vaccine nrvv ad26 (jnj 78436735) (COVID-19 VACCINE JANSSEN), as dose 1, single (Batch/Lot number: unknown) for covid-19 prophylaxis. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: DEATH (death) with onset 2022, outcome "fatal", described as "patient died from unknown cause of death"; INTERCHANGE OF VACCINE PRODUCTS (death), outcome "fatal", described as "revaccination with different covid-19 vaccine"; SUSPECTED COVID-19 (hospitalization), DRUG INEFFECTIVE (hospitalization, medically significant), outcome "unknown" and all described as "suspected covid-19 infection"; NEOPLASM MALIGNANT (medically significant), outcome "unknown", described as "cancer"; NEOPLASM PROGRESSION (non-serious), outcome "unknown", described as "cancer into overdrive, 3 new cancers". The patient underwent the following laboratory tests and procedures: Biopsy: Unknown results. The patient date of death was unknown. Reported cause of death: "Death". It was not reported if an autopsy was performed.  Clinical course as reported:  This spontaneous report received from a consumer via social media concerned an adult male of an unspecified race and ethnicity. The report did not meet the criteria as there was no reporter reported. The patient's height and weight were not reported. The patient's pre-existing medical condition included: patient had no cancer prior to vaccination. The patient received Covid-19 vaccine ad.26. cov2.s (Dose number in series 1), (suspension for injection, route of administration, batch number and expiry date were not reported) dose, start therapy date were not reported, 1 total administered for Covid-19 prophylaxis. The batch number was not reported. Per procedure, no follow-up will be requested for this case. No concomitant medications were reported. On an unspecified date, the patient was hospitalized, gets Covid-19 in hospital (Suspected Covid-19 infection). and finds out that patient had cancer (Dose number in series 1). Duration of hospitalization and discharge information were not reported. The patient also received booster with non-company suspect vaccine Pfizer BioNTech Covid-19 vaccine, (tozinameran), (Dose number in series 2), (Form of admin, Route of admin, batch number and expiry date were not reported), dose, start therapy date were not reported for Covid-19 prophylaxis which was associated with revaccination with different Covid-19 vaccine (Dose number in series 2). On an unspecified date, the patient's booster vaccination sends cancer into over drive and was diagnosed with 3 new cancers (Dose number in series 2).  Laboratory data (dates unspecified) included: Biopsy 3 new cancers. On an specified date in 2022, the patient died from unknown cause of death (Dose number in series 2). It was unspecified if an autopsy was performed. It was reported as "same exact thing happened to my dad, except before" he got the J and J, he had no cancer. First jab, hospitalized, gets covid in hospital, and finds out he has cancer. Forced to get booster Pfizer to get biopsy, sends cancer into overdrive, plus 3 new cancers. RIP dad (DOB withheld)-2022". The action taken with Covid-19 vaccine ad.26. cov2.s and tozinameran was not applicable. The outcome of cancer, suspected Covid-19 infection, cancer into over drive, 3 new cancers and Revaccination with different Covid-19 vaccine was not reported. This report was serious (Death, hospitalized caused/prolonged, and other medically important condition). Additional information: Patient had no cancer prior to vaccination. Concomitant Drugs not Reported.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Reported Cause(s) of Death: Death