Patient was giving immunization shots and a couple hours later blisters, meaning fluids were in her 2 big toes swelling triple times the size of her normal feet was rushed to the hospital in the ambulance.  Ambulance said possible allergic reaction to shots. Records received for 6 month well baby exam on 10/06/2006.   PE WNL except for infant unable to extend rt. leg or bear weight on rt. leg.  Immunizations given IPV#2, DTap #2, Hib#2, HepB #3, PCV#2. Next office visit almost 3 weeks later with c/o bilateral swelling of the toes which began the day following vax., resulting in an ER visit. Bilateral scally big toes were noted, no swelling, normal sensation, symetrical extremities. Black scab noted under Rt. toe. "Possible Bullae eruption of both toes with ? cause.  Wound has healed progressively and needs no further treatment. Not able to figure out what led to the reaction." Hospital MR received from 3rd hospital visited (11/13/06) with  chief c/o vomiting and diarrhea and report of hx of blisters on back of heel. PE: notes playful, happy well hydrated infant. D/C DX: AGE, adverse reaction to imms. Hospital MR received from ER visit of 10/06/2006 with mother's c/o large blisters on the great toes bilaterally. PMH as above with hx. of NICU stay after birth for "fluid in the lungs". PE revealed large bullae on the great toes bilaterally, mainly on the ventral side but extendidng to the dorsal side. Slight erythema noted on the heels.  Bullae were punctured releasing clear liquid, and a dressing applied.   DX: Large bullae on both great toes (etiology unknown). Follow up visit to ER on 10/08/2006 with DX: 1) Bullae s/p puncturing 2) early cellulitis. Treated with Polysporin and Keflex po. MR received from PCP for several hospital F/U visits for swollen feet. Wounds cleaned and dressed x 2. Visit 11/2/06 reports resolving scaly lesion Left great toe. DX: Allergic reaction/possibly adverse event 2' to vaccine(10/13/06) DX: Allergic reaction to vaccine with cellulitis (01/08/2007).  Follow-up: To whom ever it may concern, my daughter took her 2 months shots at her primary doctor, and was apparently fine. I took her for 4 months shots and she had an reaction to immunization and to be rushed to hospital due to blisters, fluid inside of blisters, blisters were 4 times the size of her normal sizes feet, lot of swelling in the two big toes. Hospital notified me that her 2 big toes would have falling off due to heavy swelling on purple in to her feet. I question Dr about this situation; Dr. response: was he doesn't no what was giving to her and he was supposed to run tests but refused to investigate, my primary doctor spoke to Dr. about child immunization reaction Dr. claims he will investigate in to bring baby back for investigation, brought baby back everything was taking as a joke in he was very unprofessional and will not treat or failure to investigate baby is very sick and is past due for 6 months shots 9 months behind on shots. Baby is now 7 1/2 months and was taking to 3 hospitals and noone able to give her the proper treatment that was needed and I need help finding out what she is allergic to, so this problem would not occur again and babie can receive 6 months shots because apparently 3 hospitals and primary doctor are scared to give immunization 6 months shot, due to this current problem patient is in need of 6 months shots please followup in investigation further questions in comments.