pulmonary embolism affecting the right lower lobe of their lungs; Two blood clots in right leg, they were Deep Vein Thrombosis (DVT), one DVT in left leg; a superficial vein thrombosis in their right arm; This spontaneous case was reported by a consumer and describes the occurrence of PULMONARY EMBOLISM (pulmonary embolism affecting the right lower lobe of their lungs) and DEEP VEIN THROMBOSIS (Two blood clots in right leg, they were Deep Vein Thrombosis (DVT), one DVT in left leg) in a 53-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included LEVOTHYROXINE for an unknown indication.   On 25-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 22-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 04-Apr-2021, the patient experienced PULMONARY EMBOLISM (pulmonary embolism affecting the right lower lobe of their lungs) (seriousness criterion medically significant), DEEP VEIN THROMBOSIS (Two blood clots in right leg, they were Deep Vein Thrombosis (DVT), one DVT in left leg) (seriousness criterion medically significant) and THROMBOPHLEBITIS SUPERFICIAL (a superficial vein thrombosis in their right arm). At the time of the report, PULMONARY EMBOLISM (pulmonary embolism affecting the right lower lobe of their lungs), DEEP VEIN THROMBOSIS (Two blood clots in right leg, they were Deep Vein Thrombosis (DVT), one DVT in left leg) and THROMBOPHLEBITIS SUPERFICIAL (a superficial vein thrombosis in their right arm) had resolved.            On 04-Apr-2021, patient went to the emergency room for a calf pain and 5 blood clots were discovered in her body. She was put on unspecified blood thinners but had recently stopped taking them.  Patient calling to report they had 2 doses of the Moderna vaccine. First dose was on 25Jan2021 on the left arm and the second dose was on 22Feb2021 on the right arm. About a month after the second dose, on 04Apr2021, patient went to the ER for a calf pain, and 5 blood clots were discovered in their body. Patient had  two blood clots in their right leg, they were Deep Vein Thrombosis (DVT), one DVT in their left leg, a superficial vein thrombosis in their right arm, and a pulmonary embolism affecting the right lower lobe of their lungs. Patient was put on blood thinners but has recently stop taking them. The clot are now resolved, but patient inquires if they should get the booster vaccine having had this symptoms after the second dose.  company comment: This case concerns 53 year female with no relevant medical history who experienced serious unexpected events of pulmonary embolism and deep vein thrombosis 22 days after the second dose of Modnerna Covid 19 vaccine. Rechallenge was not applicable. The benefit-risk relationship is not affected by this report.; Sender's Comments: This case concerns 53 year female with no relevant medical history who experienced serious unexpected events of pulmonary embolism and deep vein thrombosis 22 days after the second dose of Modnerna Covid 19 vaccine. Rechallenge was not applicable. The benefit-risk relationship is not affected by this report.