Diagnosed with ankylosing spondylitis; Autoimmune gastritis; Drastic hair loss; Itching legs; Impaired digestion; Tinnitus; Vision problems; Light sensitivity during the day; Pain in the left eye; Eyes appearing dark; Eye redness; Vitamin B12 deficiency; Arthritis in both knees, hips and shoulder; Neck problems; Back problems; When he raises his arm muscle start twitching; Pain in his shoulder; Pain in biceps tendon; This case was reported by a consumer via call center representative and described the occurrence of ankylosing spondylitis in a male patient who received Hepatitis B vaccine for prophylaxis.   Co-suspect products included Hepatitis B vaccine for prophylaxis and Hepatitis B vaccine for prophylaxis.   Concurrent medical conditions included arthritis.   On an unknown date, the patient received the 1st dose of Hepatitis B vaccine, the 2nd dose of Hepatitis B vaccine and the 3rd dose of Hepatitis B vaccine. On an unknown date, not applicable after receiving Hepatitis B vaccine and Hepatitis B vaccine and unknown after receiving Hepatitis B vaccine, the patient experienced ankylosing spondylitis (serious criteria GSK medically significant), autoimmune gastritis, hair loss, itchy legs, digestion impaired, tinnitus, abnormal vision, photophobia, eye pain, eye disorder, eye red, vitamin b12 deficiency, arthritis, neck discomfort, back disorder, muscle twitching, shoulder pain and muscle pain. On an unknown date, the outcome of the ankylosing spondylitis, autoimmune gastritis, hair loss, itchy legs, digestion impaired, tinnitus, abnormal vision, photophobia, eye disorder, vitamin b12 deficiency, arthritis, neck discomfort, back disorder, muscle twitching, shoulder pain and muscle pain were unknown and the outcome of the eye pain was not recovered/not resolved and the outcome of the eye red was recovered/resolved.   It was unknown if the reporter considered the muscle twitching, shoulder pain and muscle pain to be related to Hepatitis B vaccine, Hepatitis B vaccine and Hepatitis B vaccine. It was unknown if the reporter considered the ankylosing spondylitis, autoimmune gastritis, hair loss, itchy legs, digestion impaired, tinnitus, abnormal vision, photophobia, eye pain, eye disorder, eye red, vitamin b12 deficiency, arthritis, neck discomfort and back disorder to be related to Hepatitis B vaccine.  Additional details were provided as follows: The age at vaccination was not reported. The patient tested negative for Irritable bowel syndrome , Crohns disease and celiac disease. The patient received all 3 doses of Hepatitis B vaccine in the left deltoid. After vaccination, the patient experienced drastic hair loss, itching legs, impaired digestion, tinnitus, vision problems, light sensitivity during the day, pain in the left eye eyes appearing dark, eye redness. The reporter stated that, the redness of eye has disappeared, but the pain persists. The physician confirmed via endoscopy biopsy that the patient has auto immune gastritis, increased parietal cells, vitamin B12 deficiency. The patient diagnosed with ankylosing spondylitis, arthritis in both knees, hips and shoulder, vision problems, neck and back problems. After vaccination of all 3 dose, when the patient raises his arm his muscle start twitching in left arm and he has pain in his shoulder and biceps tendon.      Lab Comments: lab test performed on an unknown date. The physician confirmed via endoscopy biopsy that the patient has auto immune gastritis, increased parietal cells, vitamin B12 deficiency. The patient tested negative for IBS ( Irritable bowel syndrome ), Crohns disease and celiac disease.