Pain in left thigh/pain in her arm; Swelling in left thigh; Extensive bruising on left thigh; Extensive bruising and swelling in her left thigh/ pain in left thigh was reported as worsened; Nausea; This is a spontaneous report from a contactable consumer.   A 59-years-old female patient (age at time of onset of reaction) reported for herself that she received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection; Batch/Lot number was not reported) via an unspecified route of administration in left arm on 26May2021 at 14:30 as a 1st dose, single dose for covid-19 immunization. Medical history included COPD, allergies to flu and pneumonia vaccines, she had cancer twice, also had cancer on scalp and developed pneumonia and partial lung removed all from an unknown date and unknown if ongoing. The patient stated that she was cancer free and didn't had chemo over a year. The patient did not receive any previous immunization with the Pfizer vaccine considered as suspect or additional vaccines administered on same date of the Pfizer suspect. The patient did not receive prior Vaccinations within 4 weeks and didn't experienced any adverse event. She was not able to think of any family history. Investigation assessment was not reported. Concomitant medications included citalopram (CITALOPRAM) taken for depression from an unspecified start date and ongoing 40mg one a night at bed, acetaminophen;hydrocodone (ACETAMINOPHEN;HYDROCODONE) taken for arthritis of body from an unspecified start date and ongoing 10mg plus 325, started about 5 years ago, cefdinir (CEFDINIR) 100mg she thinks and doxycycline (DOXYCYCLINE) 875mg she thinks both taken for pneumonia, start and stop date were not reported, Started sometime in May. She took the COVID 19 shot a week or so after she finished these. The patient experienced nausea on 26May2021, instead of experiencing pain in her arm, extensive bruising and swelling in left thigh on 04Jun2021 and pain in left thigh on 06Jun2021 at 02:00, she reported she didn't recognize it, but it happened to catch her eye. She woke up in morning and found a new location of bruising. That was concerning her, because she had bruising in other locations of that leg in the left thigh area on the hip side. The new bruise was on the inside of thigh. She had a bruise on front part of her leg and on the side, it was really bad and was running down her leg. She was trying to get some direction because she didn't notice the symptom on the paperwork that she received. She went back to the pharmacy and they suggested she call Pfizer. She was going to talk to her primary care doctor to see if she recommends that she get the second shot. Relevant tests were not reported. Therapeutic measures were taken and the patient was treated for nausea, she has had previous reactions to the flu vaccine and she knows it was different from that, but she was having a reaction. She knows nausea was a part of it and she's been experiencing the nausea, but this with her leg was totally new, she has medication for this and was taking something for the nausea. The outcome of all the events was not recovered.  Information about lot/batch number has been requested.