the very highest his blood pressure went was 158/103; No Appetite; nothing tastes right; He fell off afterwards/feel really off and has been off ever since; Absolutely No Energy at All; Absolutely No Energy at All; very fatigued; Dizzy if he stands up too fast; No Appetite; nothing tastes right; This is a spontaneous report from a contactable consumer (patient's wife). A 76-year-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number: EL3302), dose 1 via an unspecified route of administration, administered in Arm Left on 07Mar2021 14:00 (13:30-14:00, at the age of 76-year-old) as dose 1, single for covid-19 immunisation; axitinib (INLYTA), via an unspecified route of administration from 12Mar2021 at an unspecified dose and frequency for clear cell renal cell carcinoma. Medical history included clear cell renal cell carcinoma from Jul2020 and ongoing, stent, blood pressure abnormal.  The patient took axitinib (INLYTA) previously and wound up with a heart attack by Nov2020 and recovered from that, he was in the hospital 03Nov2020 to 07Nov2020, liver failure/acute liver failure, the patients blood pressure was hitting stroke level, he has hoarseness, he sounds like the Godfather. Concomitant medications included ticagrelor (BRILINTA) taken for heart stents from 03Nov2020; acetylsalicylic acid (ASPIRIN) taken for stents; ezetimibe taken for stents; atorvastatin taken for stents; lisinopril taken for blood pressure. There is no prior Vaccinations (within 4 weeks), no event  following prior vaccinations, no Family Medical History Relevant to events. The patient experienced no appetite; nothing tastes right (he hasn't really eaten hardly anything since then 11Mar2021, the patient states nothing tastes right), absolutely no energy at all, very fatigued (it started right after they  came out of the doctor office which is really weird), dizzy if he stands up too fast on 11Mar2021 (had an appointment at the doctor office at 11:45 so probably about 12:30). The consumer stated that her husband (the patient) was on Inlyta and he received his first shot 07Mar2021 and four days later (11Mar2021) he started to feel really off and has been off ever since. States that she wants to know if there is an interaction between the vaccine and Inlyta. The consumer stated that there is nothing that has been new, besides the vaccine, that would make him feel the way that he is feeling. She was thinking it was possible because after he got the shot, four days later he didn't feel good because that is the only thing different. She was going to list the Oncologist because he is the one that told him to get the vaccine. The consumer stated she didn't know why he was on so many medications. The consumer clarified that the stents in his arteries is why he was on cholesterol medication, reason for cholesterol medications, Brilinta and Aspirin. There is no history of all previous immunization with the Pfizer vaccine considered as suspect, no additional Vaccines Administered on Same Date of the Pfizer Suspect. The events did not require a visit to Emergency Room and Physician Office. The consumer stated that the patient has been on and off Inlyta since Sep2020. The patient was on Inlyta and Keytruda, but Keytruda knocked him for a loop where he went into liver failure so they took him off of it and now he is strictly on Inlyta. The patient was on 5mg twice a day originally. In January or February they changed him to 1mg 3 pills twice a day, for a total of 6mg a day. The patients blood pressure was hitting stroke level so they had to reduce the strength of the Inlyta. She states by Nov2020, the patient wound up with a heart attack and recovered from that. States he was in the hospital 03Nov2020 to 07Nov2020. Caller states on 04Feb2021, the patient wound up with acute liver failure and was hospitalized 04Feb2021 to 07Feb2021 and recovered from that. She states that they don't really know if it was the Inlyta or the Keytruda. They are assuming that the liver failure was from the Keytruda. The doctor took him off of that [Keytruda] and now he is strictly on Inlyta. Keytruda: NDC, Lot, Expiration unknown. The consumer statef it was given to him at the oncology treatment center. She stated that if it is needed, call handler could get that from them, she is sure they keep a record of that. the consumer stated from the Inlyta he has hoarseness, he sounds like the Godfather, but stated they know that is from the Inlyta. She stated that she didn't think that they have any generic. [for Inlyta] she stated that when the patient was not on the Inlyta, his blood pressure was perfect and is enviable. They have been told that some side effects of Inlyta are increased blood pressure. She states that is one reason the doctor lowered the dosage, was to not get his blood pressure up too high. The consumer stated that the patient started Inlyta again on 12Mar2021 and the very highest his blood pressure went was 158/103, which still isn't awful if not consistently at that. The action taken in response to the events for axitinib was unknown. The outcome of the event He fell off afterwards/feel really off and has been off ever since was unknown, the outcome of the other events was not resolved.  No follow-up attempts are needed. No further information is expected.