On Friday, 16Apr2021, approx. 4pm, 46 yo female (who is also a Registered Nurse who is reporting these Adverse Reactions) with a medical history:  Ebstein Barr Virus (EBV), fluctuating increased LFTs; GERD; surgical repair of hiatal hernia and stomach ulcer resection. Concomitant medications: Esomeprazole 40mg PO QD; Multivitamin (MVI); Calcium  500mg 1 gummy PO QD; Vitamin B12 1 sublingual tablet PO QD; Vitamin D 10,000IU 1 capsule PO QD; Pre-&Pro-Biotic+Fiber Gummies PO QD x 2; Magnesium 1 capsule PO QD; Fish Oil 1 gummy PO QD; Tylenol enteric coated 500 mg PO PRN.  Allergies:  Injectable Progesterone; Dove Soap (Hives, erythema, pain);  received the first dose of COVID-19 Vaccine IM Left deltoid (Manufacturer: Moderna; Batch# 046B21A). On 17Apr2021, in the morning, the left arm was extremely sore and unable to lift the entire day, treatment was cold/warm compresses and Tylenol 500mg PO Q4hr x 2 doses only. By 19Apr2021, the left arm soreness resolved. On Friday, 14May2021, approx. 3:15pm, she received second dose of COVID-19 Vaccine IM Left deltoid (Manufacturer: Moderna; Batch# 033B21A). That evening, on 14May2021, she started feeling light headed around 8pm. Overnight from 14May2021 to 15May2021, she experienced an extreme headache (HA), spinal pain starting from the neck to lower back, sweating and drenching the bed sheets / clothes, rigors / uncontrollable stretching while sleeping, a 'pop' in the abdomen while the uncontrollable stretching occurred, chills / felt freezing all night, nausea, extreme left arm soreness/pain (unable to touch left arm nor move the left arm due to pain).  On Saturday, 15May2021, upon awaking around noon (she never sleeps past 8am so this was unusual to sleep until noon), she felt awful, nauseated (no vomiting), went to take a shower and was so very weak, skin hurt, skin felt painful to touch, and she had a fever that she laid on the shower floor, due to weakness / fever, in the shower letting the cold water run over her to cool her down, which did not feel very good on the painful skin.  It took every ounce of internal strength to lift herself up and dry off from the shower, she was in a daze, slowly but weakly putting clothes (pajamas) back on, head and spinal pain continued (pain scale 9 out of 10), she went out to the kitchen to attempt to make food for kids and could not do so advising the teenagers to make their own food so she could go lay down. The head pain and spinal pain was so bad, around 2pm she took 5cc of liquid Vicodin 500 mg PO once which relieved the head / spinal pain for a few hours when she took another dose of 5cc of liquid Vicodin 500 mg PO around 8pm. That night she slept with a mild fever.  The next day, Sunday, 16May2021, she woke up around 9am, felt a bit better, was able to perform activities of daily living, head ache / spinal pain was mild, fever was gone, and nausea was better, she took Tylenol 500mg PO x1 dose for discomfort. By Monday, 17May2021, she felt better, could not believe what she went through like a very bad flu / truck hit her and considered the adverse reactions resolved.  The Registered Nurse believed that all events were absolutely related to the Moderna COVID-19 vaccine.