Eyes are burning; W eakness; Dizziness; Fever of 102 F; Pouring sweat; Joints in her body started hurting really bad; Nausea; Headache; Feel extreme fatigue,couldn't even lift up her head,exhausting/felt so fatigue; Eyes were dry, had to pour water into them; Eyes were blood shot and red; Felt thirsty, thirsty, drank like a gallon and a half of water.; Severe dehydration,dehydrated for 24 hrs; She couldn't walk 3-4 stairs; Walking a short distance, I would feel out of breath; Arm got red; Arm got warm,/Arm got hot; pain in my arm", and like "someone was punching my arm". It never stopped, it kept getting worse; chills; This spontaneous case was reported by a nurse and describes the occurrence of ERYTHEMA (Arm got red), FEELING HOT (Arm got warm,/Arm got hot), DRY EYE (Eyes were dry, had to pour water into them), EYE IRRITATION (Eyes are burning) and MOBILITY DECREASED (She couldn't walk 3-4 stairs) in a 51-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 039C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 30-Jun-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Jun-2021, the patient experienced ERYTHEMA (Arm got red), FEELING HOT (Arm got warm,/Arm got hot), MYALGIA (pain in my arm", and like "someone was punching my arm". It never stopped, it kept getting worse) and CHILLS (chills). On 01-Jul-2021, the patient experienced DRY EYE (Eyes were dry, had to pour water into them), MOBILITY DECREASED (She couldn't walk 3-4 stairs), DYSPNOEA (Walking a short distance, I would feel out of breath), OCULAR HYPERAEMIA (Eyes were blood shot and red), THIRST (Felt thirsty, thirsty, drank like a gallon and a half of water.) and DEHYDRATION (Severe dehydration,dehydrated for 24 hrs). On 01-Jul-2021 at 6:00 AM, the patient experienced FATIGUE (Feel extreme fatigue,couldn't even lift up her head,exhausting/felt so fatigue) and HEADACHE (Headache). On 01-Jul-2021 at 11:00 AM, the patient experienced NAUSEA (Nausea). On 01-Jul-2021 at 2:00 PM, the patient experienced ARTHRALGIA (Joints in her body started hurting really bad). On 02-Jul-2021, the patient experienced HYPERHIDROSIS (Pouring sweat). On 02-Jul-2021 at 2:00 AM, the patient experienced PYREXIA (Fever of 102 F). On an unknown date, the patient experienced EYE IRRITATION (Eyes are burning), DIZZINESS (Dizziness) and ASTHENIA (W eakness). The patient was treated with ONDANSETRON (ZOFRAN [ONDANSETRON]) at a dose of 8 mg and IBUPROFEN (ADVIL [IBUPROFEN]) from 01-Jul-2021 to 02-Jul-2021 at a dose of four times since patient got the injection 800 mg.. On 01-Jul-2021, THIRST (Felt thirsty, thirsty, drank like a gallon and a half of water.), DEHYDRATION (Severe dehydration,dehydrated for 24 hrs) and CHILLS (chills) had resolved. On 02-Jul-2021 at 11:00 AM, PYREXIA (Fever of 102 F) had resolved. At the time of the report, ERYTHEMA (Arm got red), FEELING HOT (Arm got warm,/Arm got hot), DRY EYE (Eyes were dry, had to pour water into them), EYE IRRITATION (Eyes are burning), FATIGUE (Feel extreme fatigue,couldn't even lift up her head,exhausting/felt so fatigue), MYALGIA (pain in my arm", and like "someone was punching my arm". It never stopped, it kept getting worse), HEADACHE (Headache) and NAUSEA (Nausea) had not resolved and MOBILITY DECREASED (She couldn't walk 3-4 stairs), DYSPNOEA (Walking a short distance, I would feel out of breath), DIZZINESS (Dizziness), HYPERHIDROSIS (Pouring sweat), ASTHENIA (W eakness), OCULAR HYPERAEMIA (Eyes were blood shot and red) and ARTHRALGIA (Joints in her body started hurting really bad) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 02-Jul-2021, Body temperature: 102 f (High) Fever 102 F.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No relevant concomitant medications were reported. On 1-Jul-2021, patient used heating pad in arm three times   This case was linked to MOD-2021-245599 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 16-Jul-2021: Follow up received on 16-JUL-2021, it contains no significant information. The contact info updated and qualification corrected.