Was diagnosed with strep throat the next day after taking the first dose of Vivotif; took first dose of Vivotif and the next day picked up amoxicillin and completed a 7-day course of amoxicillin; Spontaneous report received on 06JAN2020. Additional information received on 07JAN2020 and 09JAN2020  A pharmacist reported that a female consumer "was diagnosed with strep throat the next day after taking the first dose of Vivotif" (PT: Pharyngitis streptococcal). She "took first dose of Vivotif and the next day picked up amoxicillin and completed a 7-day course of amoxicillin" (PT: Labelled drug-drug interaction medication error). She was receiving Vivotif (suspect) for immunisation and amoxicillin (co-suspect) for streptococcal sore throat. The consumer had taken her first dose of Vivotif on 23DEC2019 and was diagnosed with streptococcal sore throat on the next day. She began the seven-day course of amoxicillin on 24DEC2019 and had completed the course. She was given a new Vivotif regimen on 06JAN2019. Action taken with Vivotif with respect to the reported event "was diagnosed with strep throat the next day after taking the first dose of Vivotif" was dose interrupted while with respect to the event "took first dose of Vivotif and the next day picked up amoxicillin and completed a 7-day course of amoxicillin" was not applicable. Action taken with amoxicillin with respect to both the events was not applicable. The consumer had recovered from the reported event "was diagnosed with strep throat the next day after taking the first dose of Vivotif" while the outcome of the event "took first dose of Vivotif and the next day picked up amoxicillin and completed a 7-day course of amoxicillin" was unknown.  Company Comment: A consumer took first dose of vivotif and the next day she was diagnosed with streptococcal sore throat, and then on the same day she started taking amoxicillin and completed a 7-day course of amoxicillin (Labelled drug-drug interaction medication error).The consumer interrupted vivotif course as she started taking amoxicillin. The event streptococcal sore throat was resolved and consumer was given a new Vivotif regimen to start. The vaccination with vivotif should be postponed during and for at least three days before and after antibiotic treatment. Considering infectious pathogenesis of the event streptococcal sore throat, the causality is assessed as not related to Vivotif. Considering the nature of the event, the causality of Labelled drug-drug interaction medication error is assessed as not applicable to Vivotif.; Sender's Comments: A consumer took first dose of vivotif and the next day she was diagnosed with streptococcal sore throat, and then on the same day she started taking amoxicillin and completed a 7-day course of amoxicillin (Labelled drug-drug interaction medication error).The consumer interrupted vivotif course as she started taking amoxicillin. The event streptococcal sore throat was resolved and consumer was given a new Vivotif regimen to start. The vaccination with vivotif should be postponed during and for at least three days before and after antibiotic treatment. Considering infectious pathogenesis of the event streptococcal sore throat, the causality is assessed as not related to Vivotif. Considering the nature of the event, the causality of Labelled drug-drug interaction medication error is assessed as not applicable to Vivotif.