Venous thrombosis; Bruise on right and left leg; Could not get up; Difficult breathing; Asthma; Severe tachycardia; Felt a little weird; This spontaneous case was reported by a nurse and describes the occurrence of VENOUS THROMBOSIS (Venous thrombosis), TACHYCARDIA (Severe tachycardia), FEELING ABNORMAL (Felt a little weird), HYPOKINESIA (Could not get up) and DYSPNOEA (Difficult breathing) in a 37-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 011M20A and 011J20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Thyroid disorder NOS and Migraine. Concomitant products included TOPIRAMATE (TOPAMAX) for Migraine, LEVOTHYROXINE SODIUM (SYNTHROID) for Thyroid disorder NOS.   On 04-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 02-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Feb-2021, the patient experienced TACHYCARDIA (Severe tachycardia) and FEELING ABNORMAL (Felt a little weird). On 03-Feb-2021, the patient experienced HYPOKINESIA (Could not get up), DYSPNOEA (Difficult breathing) and ASTHMA (Asthma). On 04-Feb-2021, the patient experienced CONTUSION (Bruise on right and left leg). On 01-Mar-2021, the patient experienced VENOUS THROMBOSIS (Venous thrombosis). At the time of the report, VENOUS THROMBOSIS (Venous thrombosis), TACHYCARDIA (Severe tachycardia), FEELING ABNORMAL (Felt a little weird), HYPOKINESIA (Could not get up), DYSPNOEA (Difficult breathing), ASTHMA (Asthma) and CONTUSION (Bruise on right and left leg) had not resolved. Not Provided    DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 03-Feb-2021, Spirometry: abnormal (abnormal) Confirmed asthma. On 17-Mar-2021, Haemoglobin: low (Low) Low. On 17-Mar-2021, Red blood cell count: low (Low) Low. On 17-Mar-2021, Ultrasound Doppler: abnormal (abnormal) Venous thrombosis in her left leg. Had an arterial doppler of the right leg only because the clot was still there in the left leg.. On an unknown date, Platelet count: abnormal (abnormal) Platelet count was uncontrolled.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment details included levalbuterol for asthma and  20 mg rivaroxaban for venous thrombosis. Concomitant medication also included the use of anticoagulant from 01 Mar 2021. The reporter stated the bruise on the right was super big, it didn't hurt. Two days later it kept getting bigger and got bigger and there was no way to control it.   On 12 Apr 2021, another clot was found on right leg so now she had two clots one in left and one in right leg. Also her hemoglobin and red blood cells are still lowand the platelets are uncontrolled.   This case was linked to US-MODERNATX, INC.-MOD-2021-059897 (E2B Linked Report).   Most recent FOLLOW-UP information incorporated above includes: On 15-Apr-2021: As per the follow up received on 15 Apr 2021, the concomitant medication, platelet count details and an additional event details, i.e. a clot on right leg has been added. The outcome was also updated from unknown to not recovered as the reporter states that she still have the events previously reported.; Sender's Comments:  US-MODERNATX, INC.-MOD-2021-059897:First Dose Case