My arm was extemely sore, hot and red; i woke up and didn't feel well; felt like i was sick; felt rundown; My arm was extemely sore, hot and red; My arm was extemely sore, hot and red; tired; swollen lymph node was sore; swollen lymph node at the base of my neck along my clavicle; Redness, pain and hot at injection site; Redness, pain and hot at injection site; Redness, pain and hot at injection site; This spontaneous case was reported by a consumer and describes the occurrence of VACCINATION SITE WARMTH (Redness, pain and hot at injection site), PAIN IN EXTREMITY (My arm was extemely sore, hot and red), VACCINATION COMPLICATION (i woke up and didn't feel well; felt like i was sick), ASTHENIA (felt rundown) and SKIN WARM (My arm was extemely sore, hot and red) in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 021B21A and 027A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Concomitant products included SIMVASTATIN from 2011 to an unknown date for High cholesterol, VITAMIN D2 from 25-Feb-2021 to an unknown date for Vitamin D decreased NOS.   On 05-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 01-Apr-2021, the patient experienced VACCINATION SITE WARMTH (Redness, pain and hot at injection site), VACCINATION SITE ERYTHEMA (Redness, pain and hot at injection site) and VACCINATION SITE PAIN (Redness, pain and hot at injection site). On 02-Apr-2021, the patient experienced PAIN IN EXTREMITY (My arm was extemely sore, hot and red), VACCINATION COMPLICATION (i woke up and didn't feel well; felt like i was sick), ASTHENIA (felt rundown), SKIN WARM (My arm was extemely sore, hot and red), ERYTHEMA (My arm was extemely sore, hot and red), FATIGUE (tired), LYMPH NODE PAIN (swollen lymph node was sore) and LYMPHADENOPATHY (swollen lymph node at the base of my neck along my clavicle). The patient was treated with PARACETAMOL (TYLENOL) for Pain in arm, at a dose of UNK dosage form and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Pain in extremity, at a dose of UNK dosage form. On 07-Apr-2021, LYMPHADENOPATHY (swollen lymph node at the base of my neck along my clavicle) had resolved. On 09-Apr-2021, PAIN IN EXTREMITY (My arm was extemely sore, hot and red), SKIN WARM (My arm was extemely sore, hot and red) and ERYTHEMA (My arm was extemely sore, hot and red) had resolved. At the time of the report, VACCINATION SITE WARMTH (Redness, pain and hot at injection site), VACCINATION COMPLICATION (i woke up and didn't feel well; felt like i was sick), ASTHENIA (felt rundown), FATIGUE (tired), VACCINATION SITE ERYTHEMA (Redness, pain and hot at injection site), VACCINATION SITE PAIN (Redness, pain and hot at injection site) and LYMPH NODE PAIN (swollen lymph node was sore) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment was also reported as ice for the arm pain.   This case was linked to MOD-2021-045025.   Most recent FOLLOW-UP information incorporated above includes: On 30-Jun-2021: Follow up received on 30-JUN-2021 and contains no new information