injection really hurt; she could not use her arm at; it looks like a bruise; arm was sore /Pain; arm was sensitive to the touch; faint, modeled discoloration; had to take pain pills and sleeping pills in order to sleep / uncomfortable to sleep on arm; had little spider web looking things; arm was sensitive to the touch and swollen; red circle the size of the circumference of a coffee cup at the site of the injection / redness at the injection site; This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 76-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included colectomy and cataract extraction. Previously administered products included Shingrix with an associated reaction of polyp (1st dose received on 12th September 2019, refer case US2020014996).   In January 2020, the patient received the 2nd dose of Shingrix. In January 2020, less than a month after receiving Shingrix, the patient experienced injection site pain, injected limb mobility decreased, injection site erythema, injection site bruising, injection site swelling, pain in arm, touch sensitivity increased, skin discoloration, difficulty sleeping and skin lesion. The patient was treated with non-drug therapy (Ice Pack (No Medication)). On an unknown date, the outcome of the injection site pain, injected limb mobility decreased, injection site erythema, injection site bruising, injection site swelling, pain in arm, touch sensitivity increased, skin discoloration, difficulty sleeping and skin lesion were recovered/resolved.   It was unknown if the reporter considered the injection site pain, injected limb mobility decreased, injection site erythema, injection site bruising, injection site swelling, pain in arm, touch sensitivity increased, skin discoloration, difficulty sleeping and skin lesion to be related to Shingrix.  Additional case details were reported as follows: The patient received the 2nd Shingrix injection in unknown arm around the first week of January and had a bad reaction to it. The patient stated that the injection really hurt and that her arm was sore afterward. The patient said that the pain became so bad that she could not use her arm at all. The patient said that she had a slightly raised red circle the size of the circumference of a coffee cup at the site of the injection and that the redness kept spreading for a few days around the site. The patient also stated that the arm was sensitive to the touch and swollen and had little spider web looking things on it. The patient said that she had to take pain pills and sleeping pills in order to sleep and that it was uncomfortable to sleep on the arm and to lift it. The welling and heat took 5 days to resolve and that the redness lasted for about 2 weeks. The patient stated that at the time of reporting, most of the symptoms had resolved and that she only had a faint, modeled discoloration and redness at the injection site. The patient stated that she could still find the exact spot of the injection on her arm by pressing on it and that it looks like a bruise. The patient used ice packs on the injection site. The reporter consented to follow up. This case had been linked to the case US2020014996, reported for same patient.