Shortness of breath; Itching; my feet and my hand are still itching; I am extremely tired and my energy level is low; I am extremely tired and my energy level is low; Headache; My E coli is out and I had Vertigo and my right, my left leg rather just above the knee it goes numb; My E coli is out and I had Vertigo and my right, my left leg rather just above the knee it goes numb; My E coli is out and I had Vertigo and my right, my left leg rather just above the knee it goes numb; my left buttock I feels like I am wearing my pants, I feel like something is running down my buttock on this left side; Body ache; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  An 80-year-old female patient received BNT162b2 (BNT162B2), on 27May2022 as dose 4 (booster), single (Batch/Lot number: unknown) at the age of 80 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Asthma" (ongoing); "High blood Pressure" (ongoing); "Allergic to ShellFish" (ongoing). The patient took concomitant medications. Vaccination history included: Covid-19 vaccine (Primary Immunization series complete; unknown manufacturer), for Covid-19 Immunization; Covid-19 vaccine (DOSE 3 (BOOSTER), SINGLE , MANUFACTURER UNKNOWN), for Covid-19 Immunization. The following information was reported: DYSPNOEA (non-serious), outcome "unknown", described as "Shortness of breath"; PRURITUS (non-serious), outcome "not recovered", described as "Itching; my feet and my hand are still itching"; FATIGUE (non-serious), ASTHENIA (non-serious), outcome "unknown" and all described as "I am extremely tired and my energy level is low"; HEADACHE (non-serious), outcome "unknown"; ESCHERICHIA INFECTION (non-serious), VERTIGO (non-serious), HYPOAESTHESIA (non-serious), outcome "unknown" and all described as "My E coli is out and I had Vertigo and my right, my left leg rather just above the knee it goes numb"; PARAESTHESIA (non-serious), outcome "unknown", described as "my left buttock I feels like I am wearing my pants, I feel like something is running down my buttock on this left side"; PAIN (non-serious), outcome "unknown", described as "Body ache". The events "shortness of breath", "itching; my feet and my hand are still itching", "i am extremely tired and my energy level is low", "headache", "my e coli is out and i had vertigo and my right, my left leg rather just above the knee it goes numb", "my left buttock i feels like i am wearing my pants, i feel like something is running down my buttock on this left side" and "body ache" required emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of dyspnoea, pruritus, fatigue, asthenia, headache, escherichia infection, vertigo, hypoaesthesia, paraesthesia, pain.  Additional information: The patient underwent the following laboratory tests and procedures: Chest X-ray: Unknown results, notes: I went to the doctor I went to the emergency so they did do lab work. I went to the hospital to the emergency because I was having the problem and they did the lab work they did the Chest X-ray and then a ECG; Electrocardiogram: Unknown results, notes: I went to the doctor I went to the emergency so they did do lab work. I went to the hospital to the emergency because I was having the problem and they did the lab work they did the Chest X-ray and then a ECG. Action taken with drug was unknown. NDC number and UPC number of COVID -19 Vaccine was unknown. The patient reported that she had side effects after she had second booster on 27May and she was still having problem. First time, her first example was shortness of breath, she had itching and still have it and had her vaccination on 27May her feet and hand was itching. She was extremely tired, and her energy level was low and before that she was having headache. Her E coli was out and had Vertigo and her right, left leg rather just above the knee got numb sometimes and like almost like in a circle to the left of the knee and now her left buttock I feels like she was wearing pants, she felt like something was running down my buttock on this left side that never wear and suppose that is the body ache."  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.