right breast has been diagnosed with cellulitis; her right arm which is where the second injection site was, not just the site but her whole right arm swelled; Her voice was still weird; they think she has lymphoma; He thought it caused a severe case of laryngitis; She is all upset and hyper; He thinks it's stress; wheezing and sounded horrible; Mid left pillar idiopathy and subcarinal area neoplastic disease; mediastinal mass effect; they thought she was having a stroke; She lost her voice all of a sudden. She couldn't talk; seemed completely out of it; swollen lymph nodes/enlarged lymph node in her right lung/swollen lymph nodes on her right breast; mass in her throat; panic attack; experiencing some difficulty breathing; anxiety; This is a spontaneous report from contactable consumers (one is the patient's husband) received via medical information team and from a Pfizer-sponsored program. A 69-year-old female patient received her second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; lot number: EP7533, expiration date not reported), via an unspecified route of administration on 11Apr2021 12:00 (at the age of 69-years-old) at 2nd dose, single in the right arm for COVID-19 immunisation. Medical history included ongoing Hashimoto's disease from an unspecified date (had it for years), basal cell cancer, and the patient's immune system was compromised. It was reported that the patient's father had lymphoma and passed away due to kidney cancer. The patient's mother died at the age of 97-years-old, and was healthy. Concomitant medication included levothyroxine sodium (SYNTHROID) from an unspecified date and ongoing for Hashimoto's thyroiditis. Historical vaccine included first dose of BNT162B2 (lot number: ER8727) received on 21Mar2021 15:00 in the left arm for COVID-19 immunisation. It was reported that the patient experienced swelling on left arm where the injection was and little bit of swelling in the lymph nodes in armpit. The patient's height was 163cm, and weight was 68.01kg; both on unspecified dates. He patient's husband reported that something was happening with his wife (patient), and he cannot find the patient's symptoms on the website. It was reported that the patient had the second shot of Pfizer vaccine 3 weeks ago, this past Sunday. The second shot was given in the patient's right arm, and the first shot was given in the left arm. Everything was normal for close to three weeks. Then on Sunday, on 24Apr2021, the patient lost her voice all of a sudden. She couldn't talk, seemed to be completely out of it, and the patient's husband thought that she was having a stroke. They went to the ER (emergency room). The doctor though that the problem was that the scented detergent the patient used for her mask. The doctor thought that it caused a severe case of laryngitis. The patient was sent home. The patient's voice was still weird last week. It was also reported that the patient's right arm, and breast were swelling. On 2021, the patient experienced some difficulty breathing and anxiety. Two days ago, on 02May2021, the patient noticed that her right breast on the same side as the second shot was enlarged, heavy, and firm. The patient has no history of breast cancer. A couple of days prior (in 2021), the patient's arm was swollen. It was her whole arm. The patient was scheduled to see her dermatologist at 11:30 this morning since she was having a basal cell cancer removed from her face. The patient was all upset and hyper and was having trouble breathing a little bit. The patient's husband thought that it was stress. The patient was scheduled for surgery on her face on Wednesday this week and the patient had a panic attack on an unspecified date in 2021 so the patient was brought to the emergency room. The patient's husband stated that this was because the patient was scheduled for a surgery for basal cell cancer removal, and that the patient's breast being so large, the patient was worried. The patient had Hashimoto's disease for years, and her immune system was compromised. The extra swelling could be because her immune system was working overtime. The patient's voice was good for a while, but today, she was losing it again. The patient uses different laundry detergent now. The patient's husband stated that these never happened before, and that it could be coincidental. The patient had no reactions prior to the 3-week period after the shot. The patient was wheezing now, and the patient's husband may need to call an ambulance. The patient's husband further stated that he took the patient to the hospital (emergency room) this morning because the patient was wheezing and sounded horrible. The hospital record stated that the patient had an enlarged lymph node in her right lung and that her right breast was swollen and infected. The patient was currently in the emergency room and was not admitted to the hospital. The patient was going to have a biopsy today. After the patient's first dose, she had a little swelling on her left arm where the injection was and a little bit of swelling in the lymph nodes in her armpit. The patient's husband noticed that the patient's right arm where the second injection site was, not just the site but her whole right arm swelled, from shoulder to wrist. The patient's husband also noticed that the patient's right breast was huge. On 05May2021, the patient had MRI and CAT scans which showed "extensive mediastinal mass effect continuous from right to left side with greatest dimension of 10cm. Mid left pillar idiopathy and subcarinal area neoplastic disease". She was having a biopsy done today at the hospital". The patient's lymph nodes were swollen in the area between her lungs. On 05May2021, the patient had her COVID test which showed negative result. It was then reported that the biopsy was going to be either Ebus (as reported), which is where a tube was put down the throat, and if that did not work, there would be a mediastinoscopy performed and after that, there is a possibility that CAT scan will be done. The patient's husband reported that on Apr2021, the patient's right breast was diagnosed with cellulitis so the patient received a couple of IV (intravenous antibiotics) for the breast and it slightly improved. The patient's cellulitis could lead to sepsis that's why she was treated with IV antibiotics. The patient's MRI on an unspecified date showed that the patient's breast was clear of any swollen lymph nodes and potential cancer. The patient was also given IV antibiotics for breast enlargement, breast swelling, and breast infection. On Apr2021, the patient experienced side effects mass in her throat, swollen lymph nodes on her right breast, and cellulitis. The patient will be undergoing a biopsy today, because they think that patient has lymphoma. It was reported that the patient received her vaccination at a huge vaccination setup at a local high school. The patient was hospitalized for 3 days (unspecified dates) due to the events breast enlargement, swelling arm, breast swelling, breast cellulitis, and breast infection. The patient's husband also stated that the patient was brought to the emergency room for because the right arm started swelling and that the right breast was huge, then was taken to the hospital room that night. No other vaccine received within 4 weeks prior to the COVID vaccine. Outcome of the events  breast cellulitis, and loss of voice was recovering, for events swelling arm and panic attack was recovered on an unspecified date, and for other events was unknown.