Shortness of breath; Heart racing; Elevated blood pressure; Wheezing; Spot on her lungs; This is a spontaneous report from a contactable consumer (patient).  A 45-year-old female patient received bnt162b2 (BNT162B2), dose 2 intramuscular, administered in Arm Left on 08Sep2021 in the morning (Batch/Lot Number: FF2588) as DOSE 2, SINGLE for covid-19 immunisation at the age of 45-year-old. Medical history included ongoing blood pressure high (diagnosed years ago, has had since 2004 or 2005), ongoing arthritis (Diagnosed in 2018 or 2019), ongoing diabetes (Borderline in 2018, but started taking medication this year in 2021), urine analysis abnormal, nerve pain in joints, bone disorder, swelling, mild pain, Non-smoker. Family Medical History Relevant were Grandmother had asthma; had an oxygen tank in her house. Mother and father were both on dialysis. Concomitant medication(s) included metformin taken for Diabetes; losartan taken for Blood pressure high; hydrochlorothiazide taken for Blood pressure high, urine analysis abnormal (makes her pee); vitamin d [vitamin d nos] taken for Bone support; folic acid; methotrexate taken for arthritis; gabapentin taken for arthritis (she takes this medication at bedtime because it generally makes her sleepy), nerve pain in joints; furosemide taken for swelling; celecoxib (CELEBREX) taken for pain (doctor wanted her to take this instead of 800mg Ibuprofen for pain so it doesn't mess up her stomach), all were from an unspecified start date and ongoing. The patent received 1st dose (Lot: EW0175) on 18Aug2021 in left arm muscle in the afternoon. After the first dose, she had a little soreness in her shoulder and felt like her chest was a little different but it went away. She felt tired, and it made her sleepy and tired, but she didn't have what she's had with this 2nd dose. This 2nd dose didn't even make her arm sore. The patient experienced shortness of breath and wheezing on 24Sep2021 01:00 with outcome of not recovered, heart racing and elevated blood pressure on 24Sep2021 01:00 with outcome of recovered on 25Sep2021, spot on her lungs in Sep2021 with outcome of unknown. The patient was hospitalized for shortness of breath, heart racing, elevated blood pressure from 24Sep2021 to 26Sep2021. Therapeutic measures were taken as a result of shortness of breath, heart racing. The events Shortness of breath, heart beating too fast, and blood pressure was sky high resulted in Emergency Room visit. The clinical course was reported as: she got the 1st dose of the vaccine, then this month she got the 2nd dose on 08Sep2021. On 24Sep2021, that morning she drove herself to the ER because she couldn't hardly breathe and her heart was beating too fast. She took her blood pressure at home and it was sky high. she has never had shortness of breathe like that, and it was worse when she was laying down. At first she thought she had covid, but she didn't have any problems when eating. When she got to the ER, they put her in a wheelchair, and took her to the back right away and gave her oxygen. They did a covid test, and the doctor asked her how long she's had asthma. She doesn't have asthma and she doesn't smoke. They did two Covid tests, one they just swabbed the inside of her nose and the other one they went all the way up inside her nose; both Covid tests were negative. They kept her overnight for about 3 days total, and kept her on oxygen and was giving her breathing treatments. They also did a couple of chest x-rays. The doctor told her the day before she went home that they saw a spot on her lungs. The doctor said that it wasn't cancer, but that they were going to bring her back soon to do another x-ray to see if there are any changes. When she was discharged, they gave her albuterol treatments and pumps to do for her breathing, and she is supposed to see her doctor on Monday. She gets short of breath whenever she gets up to do something, and has to do a breathing treatment every 4-6 hours. Her lungs feel different than they did before. Before she was able to feel like she could breathe, but now she feels like her lungs are closing on her; she is wheezing and stuff, which she never had before. These all started Friday morning, 24Sep2021, at 1am. She is still doing Albuterol breathing treatments for shortness of breath. At the hospital they said her heart rate was 135 and they gave her medication to bring it down. She was on a heart monitor the whole time she was in the hospital.  Follow-up attempts are completed. No further information is expected.