This spontaneous report was received from a physician via newspaper article and refers to children. There was no information about the patients' concurrent conditions or medical history provided. Concomitant therapies were not provided. On an unknown date in 1985, children were vaccinated with M-M-R II for prophylaxis (strength, dose frequency, lot# and expiration were not reported), diphtheria toxoid (+) pertussis vaccine (unspecified) (+) tetanus toxoid (manufacturer unknown) (strength, dose, frequency, route of administration, lot# and expiration date were not reported) and poliovirus vaccine live oral (OPV-MERIEUX), orally (strength, dose, frequency, lot# and expiration date were not reported). On an unknown date in 1985, the children experienced autism. Depending on the data source, the autism-rate in 1985 was between 1 in 5,000 or 1 in 10,000. In 1986, in large part due to the brain damage being caused by diphtheria toxoid (+) pertussis vaccine (unspecified) (+) tetanus toxoid(manufacturer unknown). Childhood Vaccination Injury Act (NCVIA) was passed which partially indemnified vaccine makers from liability for CDC recommended vaccines for children. Later in 2011, the court insulated vaccine manufacturers from all liabilily, when someone was harmed or killed by a childhood vaccine. According to the author, at the reporting time also reported as "today", children routinely receive 49 doses of 14 unspecified vaccines by age 6, which were estimated that 1 in approximately 35 of them develop autism.  The physician stated: "Today, I would argue- and I do quite strongly in the book - we're simply giving too many vaccines for too many diseases that are not that dangerous. In return, we have this massive explosion in chronic disease. It's a trade. We're slightly reducing i:in certain  acute illnesses. We're having an explosion of many chronic illnesses. I think the question for us and the question for parents is, 'Is it worth it? Is the reduction in disease worth the trade-off?' That's actually the conversation I wish we could have. We don't have a realistic risk reward conversation. Vaccination are portrayed cartoonishly as offering you instant protection from whichever disease you get vaccinated for. The truth is more complicated than that." The reporter stated that it is essential to that parents need to weigh the pros and cons, and ask themselves which health risks they were willing to take to protect their child against any given disease and answer the questions:  "Do I want my child to get a rotaviruses vaccine if the risk is asthma? Do I want (them) to get a Haemophilus influenza.a type B (Hib) vaccine if the risk is a lifetime of diabetes or some other autoimmunity and a much higher risk of autism?' According the physician:" By not acknowledging the every real risks of these vaccines, parents aren't in a position to make an informed decision about whether or not they were worth it for them"; "I personally would support an immediate return to the 1985 schedule. Children were not dying the streets. It was not the Dark Ages. We have to do something radical if we're going to change this chronic disease epidemic.; Autism, for a family, is devastating. I think one of the things that really frustrates me about this epidemic is the whitewashing of autism ... The truth is not children with autism can't speak ... (they) will never live alone ... [they) will never have a job. Most children with autism require daily and hourly care [and] rue early; We can never look away from the severity of this epidemic or this disability for most of the children affected by it. It's because of the devastating nature of the disability that it puts such a strain on families; My heart goes out to families that are lower income, work two jobs or they're struggling to make ends meet and then autism gets dropped into their lives. It's simply devastating and untenable. We've got to do something about it." The outcome of autism spectrum disorder and brain injury was unknown. The relatedness between the event of brain damage and M-M-R II and poliovirus vaccine live oral (OPV-MERIEUX) were not provided.  The event of brain damage was determined to be related to the diphtheria toxoid (+) pertussis vaccine (unspecified) (+) tetanus toxoid (manufacturer unknown) The relatedness between the event of autism and suspect therapies were not provided. The events of autism and brain damage were determined to be medically significant. The event of autism was determined to be disabling.