it was possible that it was reflux; flushing; tightening of my upper chest and throat; tightening of my upper chest and throat; face also turned red; I had some itching; This is a spontaneous report from a contactable consumer or other non hcp (patient). A 75-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: solution for injection;Batch/Lot Number: ER2613; Expiration Date: Jul2021) dose 1 via an unspecified route of administration, in Left arm on 22Mar2021 14:00 (At the age 75- years old) as DOSE 1, SINGLE for covid-19 immunisation. Medical history included ongoing very mild asthma/diagnosed few years back, 3,4, or 5 years ago, fibromyalgia, she doesn't take anything for fibromyalgia, its been going on for decades, Patient was somewhat sensitive to things. has food sensitivities, she has shrunk, gluten-sensitivity. she believes and sometimes she reacts differently to some medications but can't really nail down which ones she's sensitive to. No prior vaccinations received within 4 weeks. Concomitant Products included: Patient was taking nothing that she had not normally taken. She quit taking Tylenol because it said you shouldn't be taking that beforehand because it might hurt the immune response. She has been taking her normal medications with no reaction to them. Patient stated she was feeling so relaxed and happy to get it and about 15 minutes or so later, she was getting tight in her upper chest or throat area. She stayed at the clinic maybe about an hour, her pulse didn't go up. Her face got red, she got a little itchy. She took Benadryl, the tightness in her chest decreased some and redness in her face went down and caller states five hours later the face redness was back and other symptoms were worse, so she took another Benadryl. Patient called the nurse line and they said to go to the emergency room. She went to the ER and they did an infusion of Benadryl, Pepcid, and Ativan and the flushing decreased and she was sent home. They said it was possible that it was reflux, but it was certainly quite a coincidence if it started 15 minutes after getting the vaccine. The next day she had no symptoms. Patient took Benadryl two times and redness and itching was gone by the next day. She was for sure symptoms were gone by the 23Mar2021, she had no symptoms of any kind by 23Mar2021. She was wondering if she should get the next dose. She would love to get the next dose, but she has been advised to wait 20 days or so and maybe get the Johnson and Johnson or something. She wants to know if it is safe for her to take the second dose of Pfizer covid vaccine. Therapeutic measures were taken as a result of tightening of my upper chest and throat, face also turned red, I had some itching, it was possible that it was reflux, flushing. The patient underwent lab tests and procedures which included heart rate: didn't go up, laboratory test: she had no heart problems. Outcome of event tightening of my upper chest and throat, recovered an unspecified date in Mar2021, erythema, pruritus was recovered on 23Mar2021, and for the event gastroesophageal reflux disease,her pulse didn't go up was unknown, flushing was resolving.   No follow-up attempts are possible. No further information is expected.