His white blood cells are low; He had 2 strokes; His hemoglobin won't stay within 7; He has developed anemia; He has muscle atrophy; He is experiencing persistent fevers; infectious disease; signs of inflammation; lost cognition, really confused; lost cognition, really confused; blood pressure dropped; potassium deficiency; This is a spontaneous report from a contactable consumer (patients daughter) via medical information team. A 72-year-old male patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EN6202) via an unspecified route of administration on 01Mar2021 in the left arm at dose 2 single for COVID-19 Immunization. Medical history included shingles (about fifteen years ago and they never really went away, so he's had on and off for the past fifteen years), knee replacement. Concomitant medications were not reported. Patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot number: EL9267) on 10Feb2021 in left arm for COVID-19 immunization. It was reported that eighteen days after getting the second dose of the vaccine, caller has been in 3 (going on 4) hospitals, he had 2 strokes, his hemoglobin wont stay within 7, he has developed anemia, he has muscle atrophy, and he was experiencing persistent fevers all in Mar2021. He said that its like his blood was fighting/contradicting himself and they are pretty sure that it was from the vaccine. He already had 1 blood transfusions and his white blood cells are low in Mar2021 and his ANC was normal. Caller said nothing medically makes sense. She said its like the vaccine changed the protein in the blood. Patient had been in the hospital for about nine days at this point. States he has had test after test after test, has had strokes in the medulla cerebellum, his hemoglobin wont stay above seven, has had multiple blood transfusions, developed anemia, had persistent fever, with signs of inflammation and infectious disease in Mar2021, but nothing in his body tells them. No scans, blood tests, surgery, biopsies, ultrasound, has literally had every test. Caller states the doctors are saying they have no idea what was happening, but it's something with his blood essentially fighting itself.  Caller adds he was dying, and they don't know why. Caller states just a little medical history on patient, he was 72 years old, but had the cholesterol of a twenty-year-old, the month prior to getting the second vaccine, he had a yearly work up of his heart and cholesterol and all that, they put a heart monitor on him to be sure everything was fine with that, and he had gotten a clean bill of health. States he had never had any sort of medical situation or even surgeries until two years ago, when he had a knee replacement. Caller adds the only thing funky with him, is he had a history of shingles, he got about fifteen years ago and they never really went away, so he's had on and off for the past fifteen years, and she was not sure if that's why he reacted the way he did. Caller states he was hospitalized from 19Mar2021 until 23Mar2021, when he was released to rehab. He remained at rehab from 23Mar2021 until he went home on 15Apr2021. while in rehab, patient started developing fever of unknown origin. Caller states on 25Apr2021, her father went to the emergency room. Caller states he was home ten days and was declining that whole time, with fever up and down, lost cognition, really confused in Mar2021, which they thought was a result of stroke, but he was declining rapidly. Caller adds he had fell a bunch, started losing muscle, muscle started atrophying at that point. Caller states when they took him in on the 25Apr2021, its because his blood pressure dropped in Mar2021, another issue that started all of this, he could not maintain his blood pressure, if he sat up and moved, it would drop. And that day when he tried to stand and it dropped and he slid down. They took him to the ER and he had a potassium deficiency in Mar2021 and they gave him potassium. Caller was unsure which ER he went to and he went home that day after the potassium. Caller states then on 27Apr2021, he went back to hospital, into their emergency room, and spent a couple days in the ER, but was admitted into a room once available and stayed until 15May2021. The outcome of events was unknown.  Information on the lot/batch was available, Additional information has been requested.; Sender's Comments: Linked Report(s) : US-PFIZER INC-2021751103 same reporter, drug and event, different patients;US-PFIZER INC-2021751102 same reporter, drug and event, different patients