numbness and tingling hands and legs; numbness and tingling hands and legs/to be nerve tingling, particularly in her lower legs and not feet; has chills on and off; vertigo; brain fog; she is having some immune system event, like some kind of autoimmune thing; She can barely walk across the room; she felt really not well; Incredible fatigue; This is a spontaneous report from a contactable consumer (patient) or other non HCP.  A 69-years-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EN6203, Expiration date was not reported), dose 1 via an unspecified route of administration, administered in Arm Left on 01Mar2021 17:45 (at the age of 69-years-old) as DOSE 1, SINGLE for covid-19 immunisation. The patient's medical history included ongoing leg crampy stuff, ongoing allergies, Multiple sclerosis, ongoing Hashimoto's (from 29 years), and ongoing Vitamin D deficiency. Family medical history, she stated she would just say the autoimmune stuff with her mom and her multiple sclerosis, she added there were no autoimmune folks in the trials. The patient's concomitant medication included levothyroxinetaken for Hashimoto's start and stop date were not reported (has been on this for about 29 years), vitamin d (takes sporadically, if she takes it sometimes, she takes two because she takes them sporadically. She has been on since she was diagnosed with bad Vitamin D deficiency 20 years ago), zinc taken for leg crampy stuff, magnesium taken for leg crampy stuff, calcium taken for leg crampy stuff and fluticasone  propionate, salmeterol xinafoate (WIXELA INHUB) (This was an inhaler. She takes this sporadically). The patient had no prior vaccinations within 4 weeks. The patient had no adverse events following prior vaccinations. The patient wanted to talk about or report some symptoms that she was having after the first and second vaccine. On an unspecified date patient experienced numbness and tingling hands and legs, to be nerve tingling, particularly in her lower legs and not feet, she had chills on and off, vertigo, brain fog, she having some immune system event, like some kind of autoimmune thing, She can barely walk across the room, she felt really not well. On an unspecified date in March2021 patient experienced Incredible fatigue. She stated that a symptom she was not sure was associated was numbness in her hand that she thought was a result of ping pong playing but then she did some research, and it looks as thought this was a symptom some people were experiencing. It was mostly in her hands, but also in her legs, tingling in her legs too. She clarifies numbness and tingling both left and right in hands and legs Numbness and tingling: she added that it was hard to say when this started because it was under the surface numbness. She has been playing ping pong and her arm hurt so she thought it had something to do with that. She still has the numbness and tingling; it was hard for her to tell it may have gotten better before receiving the second vaccine, but it was very much there again. She has not heard back from the doctor, and she tried to get onto the portal but has not heard back. She added that the second week after the first vaccine, she felt really not well, Fatigue started that second week. This seemed to clear up pretty well maybe a few days before she got the next dose of the vaccine, but then she got the second vaccine, and it was the same situation. There were no immediate bad responses the first day after getting the vaccines, but then the second day after receiving the vaccine she started fatigued. Caller states that the fatigue cleared up she would say she does not know but maybe 20Mar2021. She states she had maybe 3 days of not feeling bad, but then she got the second vaccine. She added that the numbness was just kind of what concerns her. She still has chills; they have not gotten better but it's just chills it was not a fever and adds it's like when the fever breaks and you get chills. She went and had testing done on the 18Mar2021, but states that she has not heard anything. She tried to contact the physician via the portal, but they did not respond. She called this morning, and her doctor was away for a week. She also has a tingling tongue and lips that has been going on for a while. She thinks it was a food allergy, but she does not have any idea, so she periodically talks to doctors about this. She adds doctors do not know what to do. They did calcium and phosphorus tests. She does not know the results. Dates of when testing was done were unclear. She added it was what it was. She just hopes it stops. She had a mother who died of Multiple Sclerosis and caller watched her mother die of it. She has autoimmune stuff; she has Hashimoto's and was paranoid with the tingling like this. Her doctor does not seem to be responsible, so she was getting panicky. The patient taking Wixela sporadically, she does not like to take medication unless she needs it. She adds she has been on wixela maybe 6 years or longer than that. She thinks she has night shade allergies, if she eats tomato sauce. Her allergist wants her to get allergy shots, they say she was allergic to cats but she does not have any. She did notice on the fact sheet that it said something about numbness and tingling and she did not know if Pfizer had a sense of how long one can expect to experience this and if there was gathered information on when this may subside. Prior to this, she got more Levothyroxine and they did a TSH test but that was before all this. They may have done a bio, she does not know the test, maybe a full panel like a blood panel. Confirms this was before receiving the vaccines. Her symptoms were not improving and sometimes they were worse. She stated she has a numbness in her hands and what appears to be nerve tingling, particularly in her lower legs and not feet. She has chills on and off, vertigo and incredible fatigue and brain fog. She stated she didn't have the stuff that Pfizer told her she may experience, except fatigue. The numbness in her hand started first thing, for like a week. Then that was compounded by other stuff following the second shot but was a little delayed. She stated she was having some immune system event, like some kind of autoimmune thing. She has gone to two primary care providers and one said try Vitamin B and she did and the other said no stop the Vitamin B and said see you in 2 weeks. She stated she doesn't imagine that she was alone in this and it was troubling and frightening for people with autoimmune disorders. She stated she knows they were not in the clinical trials but now they were in a trial. She stated she has Hashimoto's. The caller wants to know if Pfizer has any recommendations. There needs to be some assistance provided for people who were vulnerable or experiencing this. The adverse events not required emergency room visit. She went to her doctor between the first and second vaccine, sometime before 18Mar2021. The doctor keeps sending caller a survey about how well she did, but she was not going to be answering the survey at this point. Caller provides consent to contact the doctor. The patient underwent lab test and procedure which included Calcium and phosphorus tests (Blood calcium) unknown, Calcium and phosphorus tests (Blood phosphorus) on an unspecified date. The outcome of the events has chills on and off was not recovered. The outcome of the event Incredible fatigue was recovered on 20Mar2021 and outcome of the other events was unknown.   No follow-up attempts needed. No further information is expected.