was wondering if the itching was from dry skin; lots of antibodies; itching; hives/ they were red marks that made her itch; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 63-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 31Oct2022 as dose 5 (booster), single (Batch/Lot number: unknown) at the age of 63 years, in arm for covid-19 immunisation; influenza vaccine (FLU [INFLUENZA VACCINE]), on 31Oct2022 as dose number unknown, single (Batch/Lot number: unknown), in arm for immunisation. The patient's relevant medical history included: "does not have thyroid" (unspecified if ongoing). Concomitant medication(s) included: LEVOTHYROXINE taken for thyroid hormone replacement therapy (ongoing). Vaccination history included: BNT162b2 (dose 1, Lot number: EM9809), administration date: 19Feb2021, when the patient was 61-year-old, for COVID-19 immunization; BNT162b2 (dose 2, Lot number: EM6204), administration date: 12Mar2021, when the patient was 61-year-old, for COVID-19 Immunization; BNT162b2 (dose 3 (booster), Lot number: FF2587), administration date: 25Oct2021, when the patient was 62-year-old, for COVID-19 Immunization; BNT162b2 (dose 4 (booster), Lot number: FJ6369 or FJG369), administration date: 20Jul2022, when the patient was 63-year-old, for COVID-19 Immunization. The following information was reported: URTICARIA (non-serious) with onset Nov2022, outcome "recovering", described as "hives/ they were red marks that made her itch"; PRURITUS (non-serious) with onset Nov2022, outcome "recovering", described as "itching"; DRY SKIN (non-serious), outcome "unknown", described as "was wondering if the itching was from dry skin"; ANTIBODY TEST ABNORMAL (non-serious), outcome "unknown", described as "lots of antibodies". The events "itching", "hives/ they were red marks that made her itch", "was wondering if the itching was from dry skin" and "lots of antibodies" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of pruritus, urticaria, dry skin, antibody test abnormal. Additional information: Patient was taking general vitamins as additional concomitant medication. On 31Oct2022, patient also had flu shot along with the COVID shot. She had 1 shot in each arm; she didn't remember which shot she had in each arm, usually had shots in left arm. After having Bivariant COVID shot, in the middle of Nov2022, about 2 weeks after, patient started having some itching and hives, which she still has now. Patient stated it could be a coincidence but, 2 weeks after she got the shot, the itching started, still has the itching. Patient was wondering if the itching was from dry skin so, she ignored it at first. It was now tolerable but it woke her up at times. It was mostly her trunk, in stomach and back. In the beginning, she was itching with back scratcher. Still times in middle of night, she woke up itching. It was getting better. Patient was wondering if it was maybe because she took Pfizer COVID shot at the same time as flu shot, that maybe it overstimulated the system. Her primary care doctor wanted her to go to an allergist, to see if it was allergy related. Dermatologist did blood works and said it had a lot of antibodies more than normal. She went to another doctor, an immunologist. The immunologist person said she thought there were 2 different things going on, the itching as one thing and hives as another thing. She had all tests in her chart. She couldn't remember which test but, 2 of them from immunology, were elevated. Nothing was to the point where they were really concerned about it. She did have 2 blood works that were elevated. They did not think itching was related to the hives but the patient stated that it was the hives that was itching. They were red marks that made her itch. The dermatologist gave her steroid cream for it. She got a little nervous using too much because she knew she is not supposed to use too much. She only used when she had to; she was using it for 2 weeks, twice a day. She has been to 3 different doctors, saying to take a steroid. They had her on 2 loratadine (CLARITIN) and 2 cetirizine hydrochloride (ZYRTEC). She was on 4 pills and steroid cream and it didn't clear up. She was on nothing now.   The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 has been requested and will be submitted if and when received.