This is a spontaneous report from a contactable consumer (patient) via medical information team. A 65-year-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: Unknown), via an unspecified route of administration on an unknown date in Apr2021 (at the age of 65-year-old) as dose 2, single for COVID-19 immunisation. The patient medical history and concomitant medications were not reported. Historical vaccine included bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: Unknown), via an unspecified route of administration on an unknown date (at the age of 65-year-old) as dose 1, single for COVID-19 immunisation. Caller was really upset because he had his IGG test done a few months from when he got the 2nd dose of the Pfizer BioNtech Covid-19 Vaccine (Apr2021) but still tested negative. Caller stated that "Pfizer has been very neglectful, it was possible that it was not a singular person's ability, and it was possible that the Pfizer BionTech Covid-19 Vaccine only had 1/3 of the amount of vaccine as compared to moderna. Moderna vaccine recipients have ample amount of antibodies as compare to Pfizer BionTech Covid-19 Vaccine recipients. It was frustrating and Pfizer must have information/statistics on how many people does not have antibodies after being fully vaccinated because Pfizer created the vaccine". Caller was wondering why Pfizer MI was providing data for vaccine efficacy 7 days after dose 2 when he already got the Pfizer BioNtech COVID-19 vaccine a few months ago. Caller wanted to know why he got a negative result for his IGG test result after getting 2 shots of the Pfizer BioNtech Covid-19 Vaccine. Caller also wanted to know if there are tests to check the quantity of antibodies after being fully vaccinated. Response: 5.5 Limitation of Effectiveness. The Pfizer-BioNTech COVID-19 Vaccine may not protect all vaccine recipients. It was reported that we have the consumer on the other line. He was 65 years old, received the vaccine, he got both doses of Pfizer BioNTech Covid-19 vaccine. Second dose was last Apr2021 of this year and just a little bit head he was not really in good mood because he would like to report the lack of efficacy of the vaccine. He recently had antibody test and it tested negative this was something he would like to report to Drug Safety. And he had IgG (Blood immunoglobulin G), the name of the antibody IgT that was it and he also mention that there three other people took the vaccine of Pfizer who got zero antibody". When paraphrased the above concern, consumer stated, "That's correct, I took, a test if you are familiar with the IgG antibody level test. Did you ever hear IgG antibody level test? Well that I took twice both time they said did last week, both time it was said non-reactive, and I had actually zero antibody. You know what, if what you saying is I am going to give answer to your question, you are not going answer my question is that right? I have a question, my question is have you heard a people taken both vaccination and have no antibodies?". Consumer stated, "They couldn't answer the question because they put me to you. To people who have taken the Pfizer, other people don't have antibody after taking the double dose vaccination just the simple question". The case was reported as non-serious. The patient underwent lab tests and procedures which included antibody test result was negative, IGG test (blood immunoglobulin G) result was unknown result, IgG antibody level test (sars-cov-2 antibody test) result was zero antibody, COVID-19 result was negative; all were performed on an unknown date. The outcome of the event was unknown. The lot number for the vaccine, [BNT162B2], was not provided and will be requested during follow up.