extreme heartburn; Blood work showed an inflammatory response; elevated liver enzymes; Sweating; I go to ER to check for blood clots, even though it felt like heartburn; 1 minute after the shot, immediate pain and heat radiating from my chest.; 1 minute after the shot, immediate pain and heat radiating from my chest.; dizzy; BP and HR were very high; BP and HR were very high; This is a spontaneous report from a contactable Consumer or other non-HCP (patient). A 43-year-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Lot Number: EW0153), dose 2 via an unspecified route of administration, administered in Arm Left on 13Apr2021 at 14:00 (at the age of 43-year-old) as DOSE 2, SINGLE for covid-19 immunisation. Medical history included Thyroid/Hashimoto from an unknown date and unknown if ongoing. The patient had Known allergies to Penicillin. Prior to vaccination, the patient was not diagnosed with COVID-19. Concomitant medications included Levothyroxine sodium (SYNTHROID); Clonazepam (KLONOPIN); Escitalopram oxalate (LEXAPRO) and Buspirone hydrochloride (BUSPAR), all taken for an unspecified indication, start and stop date were not reported. The patient previously took his first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Lot Number: ER8727), via an unspecified route of administration, administered in Arm Left on 13Mar2021 at 14:00 (at the age of 43-year-old) as single for covid-19 immunisation and experienced fatigue, tired and weakness for about a week. The patient previously took Levaquin and experienced allergy. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Since the vaccination, the patient had not been tested for COVID-19. On 13Apr2021, at 14:00 one minute after the shot, the patient experienced immediate pain and heat radiating from my chest, Sweating, dizzy, blood clots, BP (blood pressure) and HR (heart rate) were very high, Blood work showed an inflammatory response and elevated liver enzymes. On 14Apr2021 (on Day 02), the patient experienced extreme heartburn. The clinical details of the events as follows: one minute after the shot, immediate pain and heat radiating from my chest, Sweating and dizzy. Paramedics on site had him sit and took vitals. BP and HR were very high. Over a period of 10-15 minutes these symptoms subsided. Some lingering chest pain remained for over a week. On Day 2, extreme heartburn. Dr. recommended, and he went to ER to check for blood clots, even though it felt like heartburn. On day 3, ended up in ER heartburn lasted for 24 hours. OTC medications did not work. Hospital concluded it was likely heartburn. Blood work showed an inflammatory response and elevated liver enzymes. This lasted for 6 weeks. Blood work was repeated several times during and after this period. Developed high BP or if he had underlying minor hypertension (even though going to doctors frequently his BP was on average 120/80) it was exacerbated. Average BP was 145/95 plus/minus 10 points (usually on the higher end) Currently taking 2 medication to regulate BP. The events resulted in Doctor or other healthcare professional office/clinic visit, Emergency room/department or urgent care. The patient underwent lab tests and procedures which included blood pressure measurement: high, blood pressure measurement: 120/80, heart rate: high on an unspecified date in 2021. The patient received treatment "cocktail" for heartburn from ER and unspecified BP medications. The case was non-Serious. The events did not result in death, Life threatening, Caused/prolonged hospitalization, Disabling/Incapacitating and Congenital anomaly/birth defect. The outcome of the events was not resolved.  No follow-up attempts are needed. No further information is expected.