she developed a lump underneath the chin; is it ever going to go away, it aches; is it ever going to go away, it aches, itches and it's hard.; its hard; This is a spontaneous report from a contactable consumer (patient). A female patient of an unspecified age received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/Lot Number: unknown) via an unspecified route of administration on 02Mar2021 as dose 2, single for covid-19 immunization. Medical history included cancer. Concomitant medications included palbociclib (IBRANCE) and letrozole both taken for cancer, start and stop date were not reported. Historical vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/Lot Number: unknown) via an unspecified route of administration on 09Feb2021 as dose 1, single for covid-19 immunization. The patient was calling about the covid vaccine. Ever since patient had the vaccine, she developed a lump underneath the chin. Caller states, "she do know that other people have it, she see her oncologist a "fellow" states that cancer patients have been presenting with that same thing. It ever going to go away, it aches, itches and it's hard. she had a cat scan it said there was a lump there. Its the assumption, it's from the shot. she had it in March and she still had it. The fellow said she had other people that presented with that and no other information. She was no longer interning there. She queried about It there because she taking it with Ibrance, or with Letrozole, Because the patients that are cancer patients they may also be taking these medications. In response to patient query information provided that regarding lymph nodes and Swollen lymph nodes (lymphadenopathy), which generally resolved within 10 days, was likely to have resulted from a robust vaccine-elicited immune response. Referred to health care professional as Pfizer cannot assess causality of what she was experiencing or make treatment or management recommendations. Offered to email document for review and link to latest information. A review of the Pfizer BioNTech Covid 19 Vaccine Prescribing Information did not find information about a potential interaction, or interaction study, or administration with Ibrance or Letrozole. This may not have been studied. The caller received her first dose on 09Feb2021 and second dose on 02Mar2021. Since then, the caller has developed a lump underneath her chin. She asked, you know the part of your chin that goes in. The lump was in that area and it was supposed to be soft when you press it, but the callers was hard. The caller had this lump for 9 weeks since she got the shot. The caller's doctor said that some of their patients were presenting with the same thing that the patient had after their vaccine. The lump hurts, it itches, it was hard, and cumbersome. She wanted to know, if other people have reported this and was it going to go away. Caller stated, she did know that other people have it, she saw her oncologist a fellow stated that cancer patients had been presenting with that same thing, was it ever going to go away, it aches, itches and it was hard. She had a cat scan it said there was a lump there. It was the assumption; it was from the shot. She had it in March and she still have it. Patient wanted to ask, was it there because she was taking it with Ibrance or with Letrozole? Was there any information on cancer patients having this side effect? Reporter seriousness for lump underneath her chin was unspecified. The outcome of all events was unknown.  Information on the lot/batch number has been requested.