Individual itchy welt/Hive erupting in different location days after 2nd booster; This is a spontaneous report from a contactable consumer (patient) reported in response to Non-HCP letter sent in cross referenced case follow up. A 69-year-old female patient recieved second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: CL9Z62), via an unknown route of administration at arm Right on 26Jan2021 (at approximately 03.25 PM) at single dose for covid-19 immunisation. The patient medical included Hypertension - Controlled w/medication, Elevated Cholesterol & Triglycerides - Controlled w/medication, Hypothyroidism - Controlled w/medication, Moderate Gastritis - Controlled w/medication, as needed, Osteoarthritis, Peripheral Neuropathy, Pre-Syncopy, Generalized Granuloma Annulare, Tendonitis, Onycholysis (Nail Avulsion: left big toenail removed on 25Jul2011 & right one removed on 10Nov2014), Hiatus Hernia, Mild Diverticulosis in Sigmoid Colon; Surgeries included: Malignant Melanoma - Excised from right forearm; no recurrence in Nov1988, Reduction Mammoplasty in Nov1993, Benign Tumor removed / L breast in Nov1993, Gall Bladder Cholecystectomy in 1998, Hysterectomy in Oct2011, Bariatric Sleeve Gastrectomy in Dec2012, Hernia Repair in Dec2012, Lypomas (benign fatty tumors) excised in May2013, Dual IDC Lumpectomies / L breast in Oct2017. Past drug reaction included hydroxychloroquine (Plaquenil) caused allergy, tetracycline caused stomach upset (with so many other available antibiotics on the market today, Tetracycline is no longer an Issue), pentoxifylline ER (Trental) caused multiple side effects. Historical vaccine included Typhoid Vc on 24Dec2008; Tetnus on 26Dec2008; Pneumo on 26Dec2008; Influenza on 24Dec2008, 19Oct2009, 22Nov2010, 30Nov2011, 21Nov2012, 28Oct2013, 03Nov2014, 03Nov2015, 23Oct2016, 06Oct2017, 13Sep2018, 21Sep2019, 23Sep2020: all at 0.5 cc dose and Prevnar 13 on 23Sep2020 at 0.5 ml. Family History was as follows: father (deceased) had arteriosclerotic heart disease / thromboembolism / artery occlusion; paternal family history of diabetes & heart disease; mother (deceased) had arteriosclerotic heart disease / renal failure; maternal family history included cancer & hypertension; siblings had hypertension, coronary artery disease & diabetes. Concomitant medications included levothyroxine sodium (SYNTHROID) for hypothyroidism at 50mcg / once daily, atenolol (TENORMIN) at 25mg 3 per day - 50mg in a.m. & 25mg in p.m., letrozole (FEMARA) at 2.5mg / once daily, vitamin D3 at  3000iu once daily, cyanocobalamin (VITAMIN B12) at 1000mcg / once daily, ascorbic acid (VITAMIN C) at 500mg / once daily, folic acid at 1mg / once daily , hydrochlorothiazide at 25mg / once daily, pantoprazole sodium sesquihydrate (PROTONIX) at 40 mg / originally: once daily - now: every other day, alprazolam (XANAX) at 0.5mg, as needed, paracetamol (TYLENOL, caplets) 500 mg ea. -or- arthritis strength; 650mg ea., cetirizine hydrochloride (ZYRTEC, 10mg), alginic acid/aluminum hydroxide/sodium bicarbonate (GAVISCON) and simvastatin (ZOCOR) at 40mg / once daily, Late Night. Past drug event included: Tetracycline- Stomach upset only; with so many other available antibiotics on the market today, Tetracycline is no longer an Issue; Pentoxifylline Er (Trental) - Multiple side effects. Historical vaccine included the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection; lot number EL3346) via an unspecified route of administration, on 05Jan2021 at about 17:00 (at the age of 69-year-old) as a single dose in the right arm for COVID-19 immunization and experienced vaginal bleeding 06-JAN-2021 06:30 recovered on 17-JAN-2021, Fear and Paranoid in Jan2021. On 26Jan2021, the patient received 2nd Pfizer Covid-19 "booster" vaccine at approximately 03.25 PM and on 30Jan2021 in the evening, the patient experienced Individual welts (Hive/Urticaria) erupting at different location starting 4 days after 2nd booster vaccine on 26Jan2021 (Time of onset: PM). A single itchy welt / hive erupted on the upper portion of the left side of back (below the shoulder blade). Eventually subsided. On 01Feb2021 late afternoon, another single itchy welt / hive erupted on the back of left hand (near the thumb). That eventually subsided. On 02Feb2021 early morning, a single itchy welt / hive erupted on the top my right forearm (just below the elbow). After several minutes, it receded. A couple of hours later, one flared up on the side of my right thigh (approximately 3 inches above the knee). That, too, eventually went down. On 03Feb2021, patient went to the office of a physician board certified in allergies & immunology. Physician (He) said the reaction was due to my body creating antibodies (for protection against the Coronavirus) after receiving the booster shot days earlier and it's a delayed response & would eventually stop. The patient was not hospitalise due to the event. No treatment was received. Still experiencing events. On 09Jan2021, ER (emergency room) Blood work results included urinalysis. Patient stated that any additional test results, if required, would to be obtained from Physician. Outcome of the event was not recovered.  Information regarding lot/batch number has been requested.