Headache/ her aches got worse over time as well; Fatigue worsened; all over joint and body pain/ her aches got worse over time as well; all over joint and body pain/ her aches got worse over time as well; sick intermittently; This is a spontaneous report received from a contactable reporter (Consumer or other non HCP). The reporter is the patient.  A 42-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 06Oct2022 as dose number unknown (booster), single (Batch/Lot number: unknown) at the age of 42 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "Cystic fibrosis" (unspecified if ongoing), notes: reporter said this is genetic so reported it as at birth. There were no concomitant medications. Vaccination history included: Covid-19 vaccine (Primary Immunization series complete; unknown manufacturer), for COVID-19 immunization; Bnt162b2 (DOSE NUMBER UNKNOWN, SINGLE, Batch/Lot number: unknown), for COVID-19 immunization, reactions: "all over joint and body pain", "Fatigue", "Headache". The following information was reported: FATIGUE (non-serious) with onset 06Oct2022, outcome "not recovered", described as "Fatigue worsened"; HEADACHE (non-serious) with onset 06Oct2022, outcome "not recovered", described as "Headache/ her aches got worse over time as well"; ARTHRALGIA (non-serious), PAIN (non-serious) all with onset 06Oct2022, outcome "not recovered" and all described as "all over joint and body pain/ her aches got worse over time as well"; ILLNESS (non-serious) with onset Oct2022, outcome "unknown", described as "sick intermittently". The events "headache/ her aches got worse over time as well", "fatigue worsened", "all over joint and body pain/ her aches got worse over time as well" and "sick intermittently" required physician office visit. Therapeutic measures were taken as a result of headache, fatigue, arthralgia, pain, illness.  Additional information: The patient said that there was a confirmation of it being from the vaccine and had concern that it lasted longer than intended side effects; the confirmation was at the doctor appointment on 18Oct2022. The patient got the Pfizer COVID-19 vaccine bivalent booster (NDC number: 59267-0304-01) on 06Oct2022, and she needed to report adverse reactions as currently she was off work for being sick intermittently, but not intermittently since vaccine. Currently, she was on steroids to suppress her immune system that she started on the same day as her doctor appointment on 18Oct2022. She was taking Prednisone 20 mg once a day by mouth, and the reason for that was due to having headaches, fatigue, all over joint and body pain since the vaccine was administered, with no other signs of being sick. She was not congested, had no cough; it was like the reaction after her initial doses, but it had not gone away. Her symptoms started on 06Oct2022, and her headaches stayed about the same since they started. She had treated those with ibuprofen over the counter, she was taking 600 mg as needed (PRN). Her fatigue treatment was taking time off work and sleeping, and it got worse over time. Her aches got worse over time as well. She said that she was going to have a recheck on Monday with her doctor about how long she would be going to take the Prednisone. The patient didn't have injection records and vaccine card to provide lot information from previous doses of Pfizer COVID-19 vaccine as those were in her employee file.  The information on the batch/lot number for BNT162B2, BNT162B2 OMI BA.4-5 has been requested and will be submitted if and when received.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201249232 same reporter, patient, product, and event; different dose;