hipercoagulation/Hypercoagulation; chronic phlebitis on upper extremities; clot on my arms/severe thrombosis; pain on my arms/severe pain on the left, clarified as her left foot; Apr 3/21 was the second dose. And next day I started feeling bad; big bruise, describing it as red, green, black, really horrible; hemorrhoids; big edema, this was a large area of left arm; Yesterday she couldn't walk properly; upper left foot, was inflamed; bleeding severely in her rectal area; This is a spontaneous report from a contactable consumer. A 60-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) at the age of 60-years-old, via an unspecified route of administration, administered in Arm Right on 03Apr2021 (also reported as 05Apr2021) (Batch/Lot Number: EW4109) as dose 2, single for COVID-19 immunization. The patient medical history was not reported. The patient had no known allergies. Concomitant medication included levothyroxine sodium (SYNTHROID) taken for an unspecified indication, start and stop date were not reported. Historical vaccine included first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration, administered in Arm left on 21Feb2021 (also reported as 26Feb2021) 15:45 (Batch/Lot Number: ER1742) as dose 1, single for COVID-19 immunization. The patient had no other vaccines in four weeks. 03Apr2021 was the second dose. And next day, 04Apr2021 she started feeling bad. The patient was having hypercoagulation and chronic phlebitis on upper extremities, clot on her arms. She was on Xarelto treatment. Never had any issue before. These vaccines were taking in # and she went back to US due to the severity of her problem. She visited hematology, rheumatologist and cardiovascular specialist and has 47 labs, also eco doppler on upper extremities. She had pain on her arms and severe thrombosis on 05Apr2021. She will be able to provide the names of all doctors that are seeing her. The events hypercoagulation and chronic phlebitis on upper extremities, clot on her arms occurred on 05Apr2021 12:30 caused hospitalization for 4 days and was treated with anticoagulants. The events resulted in Doctor or other healthcare professional office/clinic visit, Emergency room/department or urgent care. She first had to wait 40 days between the shots because they ran out. This was in the first report. The caller reports she never realized it was an adverse effect until after the second. A week later started bleeding rectally with clots severely, saying it was not a lot but permanently bleeding. She thought it was hemorrhoids though she never had them before. She then went to withheld because her doctor wanted to perform a study on her breast, an MRI with contrast. When it was put in her left arm she had big bruise, describing it as red, green, black, really horrible and big on her arm and she never had that happen before. Six days later, after the MRI, she had a biopsy of a suspicious mass on left breast. The preformed the procedure and in the right arm did contrast and didn't have any problem. Afterward, her left breast was incredibly red, black , red, green with a big clot but she was told it was normal, she never thought it was a side effect to the shot. A week later, she came back to withheld, withheld where she had a colonoscopy done due to the bleeding and clots. They found 2 great big hemorrhoids and the doctor put bands on them. Six days later she had external clots and was bleeding again, she repeats she never had this before, so they went back for another procedure and did it again, put other bands and trying to fix all of this. Then 3 days after this, she had a big clot on her right arm in the superficial vein of her right arm and big edema, this was a large area of left arm. The caller relays she has pictures if needed. There are also problems with the veins in her hands, it was described on the ultrasound as chronic phlebitis. The caller was in hospital for 4 days and started on Xarelto, an anticoagulant, at 15mg every 12 hours. She reports the veins up until now are burned and painful and feel like they are wanting to break. She remarks she doesn't think it help but the clot is a little bit less. On 05Jul2021 she was bleeding severely in her rectal area, and had another intervention. During this they found a new clot, like a hemorrhoids and more bands were placed to control it. This week is the first time has felt better since this started, the doctor said this was due to the anticoagulants and that they don't think she has any more clots. In the last week she has severe pain on the left, clarified as her left foot, when she lifts her leg and it is very painful. Yesterday she couldn't walk properly. The vein on the left foot, the exterior of the upper left foot, was inflamed or there was another thrombi. She was using antiembolic socks, she does this on her own. These are the white long sock to prevent clots. She went to withheld and sees a wonderful rheumatologist, immunologist, and cardiologist. She had a 47 blood study done and the thing that was relevant from that was that it showed she has hypercoagulation and recommend 6 months to 1 years of Xarelto. The doctors told her that they cannot confirm she never had anything before but believe probably, this was an adverse reaction to the vaccine. The patient had no prior vaccination. The patient underwent lab test and procedures which included Nasal Swab, PCR, covid test result: Negative. The patient received treatment for events hypercoagulation and chronic phlebitis on upper extremities, clot on her arms, pain on arms and feeling bad and outcome was recovered with lasting effects. The outcome of other events was unknown.  Event occurred in a country different from that of the reporter. This may be a duplicate if the reporter also submitted directly to his/her local agency.  Follow-up attempts are completed. No further information is expected.