Fever for a couple of nights and then was fine; Positive COVID-19 home rapid test, months after 1st booster; This spontaneous case was reported by an other health care professional and describes the occurrence of PYREXIA (Fever for a couple of nights and then was fine) and COVID-19 (Positive COVID-19 home rapid test, months after 1st booster) in a 91-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No Medical History information was reported.   On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form and first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 09-May-2022, the patient experienced PYREXIA (Fever for a couple of nights and then was fine) and COVID-19 (Positive COVID-19 home rapid test, months after 1st booster). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) at an unspecified dose and frequency. On 15-May-2022, COVID-19 (Positive COVID-19 home rapid test, months after 1st booster) had resolved. At the time of the report, PYREXIA (Fever for a couple of nights and then was fine) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 09-May-2022, SARS-CoV-2 test: positive (Positive) Positive. On 15-May-2022, SARS-CoV-2 test: negative (Negative) Negative.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant product use was not provided by the reporter.  The patient had 2 primary and a booster dose of Moderna COVID-19 vaccine, had a home rapid test and tested positive on Monday 9-May-2022. The patient had a fever for a couple of nights and then she was fine. She was no longer positive for COVID-19. Company comment This spontaneous case reported by a health care professional concerns a 91 year old female patient no medical history reported, who experienced the unexpected non-serious ADR of Covid 19 with a positive rapid test, and the non serious event of pyrexia, unknown days after receiving the first booster dose of mRNA-1273 vaccine in the covid 19 vaccination series. The patient had 2 primary and a booster dose of Moderna COVID-19 vaccine on unknown dates, she had a home rapid test and was tested positive, months after the first booster dose on 9-May-2022. She was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) at a dose of 1 dosage form. The patient had a fever for a couple of nights and then she was fine. The events had resolved. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   This case was linked to MOD-2022-568298, MOD-2022-568684, MOD-2021-024069 (Patient Link).; Sender's Comments: This spontaneous case reported by a health care professional concerns a 91 year old female patient no medical history reported, who experienced the unexpected non-serious ADR of Covid 19 with a positive rapid test, and the non serious event of pyrexia, unknown days after receiving the first booster dose of mRNA-1273 vaccine in the covid 19 vaccination series. The patient had 2 primary and a booster dose of Moderna COVID-19 vaccine on unknown dates, she had a home rapid test and was tested positive, months after the first booster dose on 9-May-2022. She was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) at a dose of 1 dosage form. The patient had a fever for a couple of nights and then she was fine. The events had resolved. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.