Feeling tired; sluggish; mild redness at the injection site; arm was sore; 3rd dose 01Sep2021; 3rd dose 01Sep2021; This is a spontaneous report received from a contactable Health Care Professional reported for a consumer (patient). A 36-years-old female patient received third dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EW 0153, Expiration date: unknown) intramuscular, administered in left arm on 01Sep2021 at 08:53 am (age at vaccination was 36 years) as dose 3 (booster), single for COVID-19 immunization. The patient's medical history was not reported. The patient did not have any known allergies. Concomitant medications included fluoxetine taken for an unspecified indication (for approx. 4 years) and zolpidem taken as need for sleep, occasionally. The patient previously received most recent non-COVID vaccine influenza administered in Oct/Nov2020. The patient previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EH 9899, Expiration date: unknown) intramuscular, administered in left arm on 21Dec2020 at 11:23 am (age at vaccination was 35 years) as dose 1, single and second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EL 1284, Expiration date: unknown) intramuscular, administered in left arm on 11Jan2021 at 11:32 am (age at vaccination was 35 years) as dose 2, single for COVID-19 immunization and experienced her fingers in her left arm (here she got her vaccine) started going numb, was losing her breath/short of breath, her body went limp and she fell out of the bed, prolonged panic attack, her eyes rolling in the back of her head, unable to sit up, unable to swallow, lost feeling in her fingers and legs, she was shaking profusely, her heartbeat felt really irregular, fluctuating blood pressure, tingling, trembling, difficulty speaking and drooling after the second dose of vaccine. The patient did not receive any recent vaccines for any other conditions prior to the event being reported. The patient did not receive any recent vaccines for SARS-CoV2 other than Pfizer-BioNTech COVID-19 Vaccine prior to the event being reported. The patient had not received any other vaccines around the time of Pfizer-BioNTech COVID-19 vaccine vaccination. The patient described having anxiety related to vaccination but decided to receive three doses based on her risk as a hospital employee. The patient received a third dose of vaccine on 01Sep2021 at 08:53 am (off label use) without recurrence of the symptoms associated with administration of the second dose. On an unspecified date, the patient was feeling tired and sluggish and had some mild redness at the injection site and her arm was sore. But no cardiac, respiratory or histamine-mediated allergic symptoms were noted following the third dose. The patient underwent lab test which included subsequent and extensive cardiac workup such as EKG (Electrocardiogram): result unknown, stress test: result unknown, Holter monitoring: multiple, frequent, recurring PVCs were noted during Holter monitoring and blood pressure: fluctuating blood pressure- high/low. The MRI (Magnetic resonance imaging) of her heart was scheduled on 23Sep2021. It was reported that the Pfizer product did not have a causal effect to the adverse event. The outcome of the events was unknown.  No follow-up attempts are possible. No further information is expected.