Urinary tract infection; Booster; Lost appetite; Nervous; Memory not as good; I'm grasping for breath; Trembling; Grumpy; Fidgety; Jittery; Lost 10-15 pounds; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 77 year-old female patient received bnt162b2 (COMIRNATY), administered in arm left, administration date 25Oct2021 (Lot number: FD0809) at the age of 77 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "lymphedema" (unspecified if ongoing), notes: The therapy is lymphedema for lymphedema from breast cancer.; "blood clots", start date: 2009 (unspecified if ongoing); "diagnosed allergies" (unspecified if ongoing); "compromised immune status" (unspecified if ongoing); "respiratory illness" (unspecified if ongoing); "genetic/chromosomal abnormalities" (unspecified if ongoing); "endocrine abnormalities" (unspecified if ongoing); "diabetes" (unspecified if ongoing); "obesity" (unspecified if ongoing). Concomitant medication(s) included: ELIQUIS taken for haemorrhage urinary tract, start date: 2009 (ongoing); LOSARTAN taken for hypertension, start date: 2015; CARVEDILOL taken for hypertension, start date: 2015; SERTRALINE taken for restlessness, start date: 2015. Vaccination history included: Bnt162b2 (Dose: 1, Lot: ZTC2948, Expiration: Unknown.  , Anatomical Location: left arm), administration date: 16Mar2021, when the patient was 77 years old, for COVID-19 immunization; Bnt162b2 (Dose: 2, Lot: ZTL5384026 , Expiration: Unknown.  , Anatomical Location: left arm), administration date: 13Apr2021, when the patient was 77 years old, for COVID-19 immunization; Flu shot (She had a flu shot 2 weeks before the last dose.), administration date: 2021. The following information was reported: IMMUNISATION (non-serious) with onset 25Oct2021, outcome "unknown", described as "Booster"; DECREASED APPETITE (non-serious) with onset Oct2021, outcome "not recovered", described as "Lost appetite"; NERVOUSNESS (non-serious) with onset Oct2021, outcome "not recovered", described as "Nervous"; AMNESIA (non-serious) with onset Oct2021, outcome "not recovered", described as "Memory not as good"; DYSPNOEA (non-serious) with onset Oct2021, outcome "not recovered", described as "I'm grasping for breath"; TREMOR (non-serious) with onset Oct2021, outcome "unknown", described as "Trembling"; IRRITABILITY (non-serious) with onset Oct2021, outcome "unknown", described as "Grumpy"; PSYCHOMOTOR HYPERACTIVITY (non-serious) with onset Oct2021, outcome "unknown", described as "Fidgety"; FEELING JITTERY (non-serious) with onset Oct2021, outcome "unknown", described as "Jittery"; WEIGHT DECREASED (non-serious) with onset Oct2021, outcome "not recovered", described as "Lost 10-15 pounds"; URINARY TRACT INFECTION (non-serious) with onset 12Nov2021, outcome "unknown", described as "Urinary tract infection". The event "i'm grasping for breath" was evaluated at the physician office visit and emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section.  Follow-up (18Nov2021): This is a follow-up spontaneous report received from a contactable consumer.  Follow-up attempts are completed. No further information is expected.