Adrenal gland insufficiency; thyroid issues; fatigue; lymph nodes enlarged; abdominal pain; This spontaneous case was reported by a physician and describes the occurrence of ADRENAL INSUFFICIENCY (Adrenal gland insufficiency) in a 68-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 031M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) for Rheumatoid arthritis.    The patient's past medical history included Cartilage disorder from October 2020 to 15-Jan-2021, Hip dislocation from October 2020 to 15-Jan-2021, COVID-19 (26-Oct-2020 nasal swab test COVID-19 positive) on 20-Oct-2020, Surgery (hand surgery) in 2011 and Hip surgery in 2020. Concurrent medical conditions included GERD since 1962, Indigestion since 1962, Pain in hip since 2011, Joint pain since 2011 and Drug allergy (MORPHINE ALLERGY MANIFESTED BY RASH, VOMITING, DELIRIUM  CODEINE ALLERGY MANIFESTED BY RASH, VOMITING, DELIRIUM  OXYCODONE ALLERGY MANIFESTED BY RASH, VOMITING, DELIRIUM).   In June 2020, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) 40 mg every two weeks. On 09-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 12-Feb-2021, the patient experienced ABDOMINAL PAIN (abdominal pain). On 18-Feb-2021, the patient experienced LYMPHADENOPATHY (lymph nodes enlarged). On an unknown date, the patient experienced ADRENAL INSUFFICIENCY (Adrenal gland insufficiency) (seriousness criterion medically significant), THYROID DISORDER (thyroid issues) and FATIGUE (fatigue). The patient was treated with CIPROFLOXACIN (CIPRO [CIPROFLOXACIN]) at an unspecified dose and frequency and PREDNISONE at an unspecified dose and frequency. At the time of the report, ADRENAL INSUFFICIENCY (Adrenal gland insufficiency), ABDOMINAL PAIN (abdominal pain), THYROID DISORDER (thyroid issues), LYMPHADENOPATHY (lymph nodes enlarged) and FATIGUE (fatigue) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In February 2021, Blood test: unknown (Inconclusive) Blood work done-results unknown. On 18-Feb-2021, Computerised tomogram: abnormal (abnormal) Enlarged lymph nodes in abdominal region.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered ABDOMINAL PAIN (abdominal pain) and LYMPHADENOPATHY (lymph nodes enlarged) to be possibly related. No further causality assessments were provided for ADRENAL INSUFFICIENCY (Adrenal gland insufficiency), THYROID DISORDER (thyroid issues) and FATIGUE (fatigue).    The patient was treated with CIPRO and PREDNISONE (indication not specified).  Company comment:Very limited information regarding these events has been provided at this time. The events are probably related to the patient's comorbidities, further information required.; Sender's Comments: Very limited information regarding these events has been provided at this time. The events are probably related to the patient's comorbidities, further information required.