knows others that have gained as well after receiving the Pfizer vaccine, one about 30 pounds, one about 10; shut down my metabolism; This is a spontaneous report from a contactable consumer. This consumer reported similar events for 2 patients. This is second of two reports. A 59-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Batch/lot number: not provided), via an unspecified route of administration on an unspecified date as a single dose for COVID-19 immunisation. The patient medical history included Hashimoto's thyroiditis from an unknown date and unknown if ongoing. Concomitant medications were not provided. On an unknown date, the patient experienced have gained as well after receiving the Pfizer vaccine, one about 30 pounds, one about 10, shut down metabolism. she can't eat anything anymore, because every time she eats or drinks anything, she gains weight. Sometimes has a glass of wine to go to sleep at night, and that's like, 120 calories, then mentioned something else she ate yesterday. States repeatedly that most people don't care, and just buy bigger clothes, but this is "really annoying". States her weight does fluctuate, but this is extreme and she cannot take it off. Reports that she has gained 15 pounds and nothing is going to fit her this fall, knows others that have gained as well after receiving the Pfizer vaccine, one about 30 pounds, one about 10. She asked them both if they had underlying thyroid condition, and they said yes. She reports that she has Hashimoto's thyroiditis, and has high antibodies, thyroid is 2.3. This vaccine has completely shut down my metabolism and there's nothing else she can do. States tape measure went down because of exercise, but the scales continue to go up. She states that she wishes more people will report it, as well as that most of them are men. Says repeatedly that none of her clothes fit, but that it is "only 10Aug, so I have some time before fall". Caller reports that she had blood tests a month ago and they were normal (liver, pancreas, sonogram) and comprehensive aside from gynecologist. States the bloating is not in her hips or waist and is up to ribs. States that she looks healthy at 5'5" and 130#. Has been exercising and eating better. Is ready to "just never eat again". Did not have exact dates of vaccinations, but said they were 2 months ago.  Attempted to gather additional demographic and PCP information, but caller hung up before providing that. Mentions her doctor may increase her water pill. Tried Synthroid, but she could not tolerate that, because TSH is already normal, per patient report. she is not the only one experiencing this side effect and knows of people who have had the same side effect of weight gain. She has an underlying thyroid condition and this Covid vaccine makes her put on so much weight, severe weight. She doesn't even eat and keeps gaining weight. Knows of a pizza guy who gained 30 pounds and someone she orders clothes from has also gained 30 pounds and she has gained 15 pounds. She has to watch every morsel of food and is just frustrated. Does not eat more than 500 calories a day or anything like that and it is so frustrated. Attempts made to slow caller to clarify other people with same side effect. Wanted to know how long report would take and if anyone has reported any of this and what kind of doctor she should see about this. Declines to provide an address or email. Declines to provide any further report details and would like someone to answer her questions. The outcome of the events was unknown.  The lot number for the vaccine, [BNT162B2], was not provided and will be requested during follow up.  Follow-up activities closed. Batch/lot number not available for [vaccine/BNT162B2], F/UP closure to be managed as significant.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101099307 same reporter/product, different patient / event.;US-PFIZER INC-202101097977 same reporter/product, different patient / event.