Neuropathy all over the body after 2nd shot; Allergic reaction after 2nd shot; Biopsy Diagnosis of inflammation after 2nd shot; Burning sensation all over the body after 2nd shot; Feels like Electric Shock all over body after 2nd shot; Extreme itching all over body after 2nd shot; Big Rash on the left leg  on & off, after 2nd shot/Rash moves to the stomach on & off, after 2nd shot; Joint Pain after 2nd shot/The Joint Pain still comes and go; Muscle ache after 2nd shot; This spontaneous case was reported by a consumer and describes the occurrence of NEUROPATHY PERIPHERAL (Neuropathy all over the body after 2nd shot) in a 51-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 026B21A and 041L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Eczema (Eczema on the hands, mostly on the right hand).   On 01-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 30-Mar-2021, the patient experienced NEUROPATHY PERIPHERAL (Neuropathy all over the body after 2nd shot) (seriousness criterion medically significant), VACCINATION COMPLICATION (Allergic reaction after 2nd shot), INFLAMMATION (Biopsy Diagnosis of inflammation after 2nd shot), BURNING SENSATION (Burning sensation all over the body after 2nd shot), ELECTRIC SHOCK SENSATION (Feels like Electric Shock all over body after 2nd shot), PRURITUS (Extreme itching all over body after 2nd shot), RASH (Big Rash on the left leg  on & off, after 2nd shot/Rash moves to the stomach on & off, after 2nd shot), ARTHRALGIA (Joint Pain after 2nd shot/The Joint Pain still comes and go) and MYALGIA (Muscle ache after 2nd shot). On 29-Dec-2021, MYALGIA (Muscle ache after 2nd shot) had resolved. At the time of the report, NEUROPATHY PERIPHERAL (Neuropathy all over the body after 2nd shot), VACCINATION COMPLICATION (Allergic reaction after 2nd shot), INFLAMMATION (Biopsy Diagnosis of inflammation after 2nd shot), BURNING SENSATION (Burning sensation all over the body after 2nd shot), ELECTRIC SHOCK SENSATION (Feels like Electric Shock all over body after 2nd shot), PRURITUS (Extreme itching all over body after 2nd shot) and RASH (Big Rash on the left leg  on & off, after 2nd shot/Rash moves to the stomach on & off, after 2nd shot) outcome was unknown and ARTHRALGIA (Joint Pain after 2nd shot/The Joint Pain still comes and go) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 30-Mar-2021, Biopsy: diagnosis of inflammation Diagnosis of inflammation.         No treatment medications provided. No concomitant medication provided.; Sender's Comments: This case concerns a patient, with medical history (eczema), who experienced the serious unexpected event(s) of Neuropathy peripheral and additional non-serious events. The event(s) started occurring approximately within 1 day(s) after the 2nd dose of mRNA-1273, Moderna COVID-19 Vaccine. The rechallenge was considered NA. The benefit-risk relationship of mRNA-1273, Moderna COVID-19 Vaccine is not affected by this report.