The patient is pregnant as of 07Jan2022; This spontaneous prospective pregnancy case was reported by a pharmacist and describes the occurrence of MATERNAL EXPOSURE BEFORE PREGNANCY (The patient is pregnant as of 07Jan2022) in a 38-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014F21A, 042B21A and 045A21A) for COVID-19 prophylaxis.     No Medical History information was reported.   On 17-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 14-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 24-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. Last menstrual period and estimated date of delivery were not provided. On 24-Oct-2021, the patient experienced MATERNAL EXPOSURE BEFORE PREGNANCY (The patient is pregnant as of 07Jan2022). On 24-Oct-2021, MATERNAL EXPOSURE BEFORE PREGNANCY (The patient is pregnant as of 07Jan2022) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No concomitant and treatment medications were reported.  The reporter stated that the patient was pregnant as of 07-Jan-2022.  The patient was advised by her doctor to get a second booster dose (4th dose) so the reporter asked, if the patient can get the second booster dose.  The reporter stated that the patient would get a prescription from the doctor for the second booster dose (4th dose) of the Moderna vaccine.  Company comment-This spontaneous case concerns a 38-year-old, female pregnant (at the time of report) patient with no medical history reported, experienced unexpected non-serious event of Maternal exposure before pregnancy as she had received third dose (1st booster) of mRNA-1273 vaccine approximately 2 months 14 days before pregnancy. Patient had received 1st and 2nd dose of Moderna vaccine at an interval of 28 days and 1st booster approximately after 6 months. The patient is pregnant as of 07Jan2022 (approximately 2 months 14 days after 3rd dose). No further details on Last menstrual period/Expected date of delivery, gestation period, lab test results were reported. Outcome of the event was not known at the time of report. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   Reporter did not allow further contact; Sender's Comments: This spontaneous case concerns a 38-year-old, female pregnant (at the time of report) patient with no medical history reported, experienced unexpected non-serious event of Maternal exposure before pregnancy as she had received third dose (1st booster) of mRNA-1273 vaccine approximately 2 months 14 days before pregnancy. Patient had received 1st and 2nd dose of Moderna vaccine at an interval of 28 days and 1st booster approximately after 6 months. The patient is pregnant as of 07Jan2022 (approximately 2 months 14 days after 3rd dose). No further details on Last menstrual period/Expected date of delivery, gestation period, lab test results were reported. Outcome of the event was not known at the time of report. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.