had a little cough; itching in throat; blood came out of nose when blew her nose; blisters in mouth, blisters on side of nose / The blister was like an open wound and has blood; patient had a bad reaction; face was very hot, face felt warm; After the booster, patient had a little bit of fever/ slight fever; After the booster, patient had weakness / still feels weakness, feels not so energetic; tested positive for COVID; This spontaneous case was reported by a patient and describes the occurrence of ASTHENIA (After the booster, patient had weakness / still feels weakness, feels not so energetic), COVID-19 (tested positive for COVID), COUGH (had a little cough), THROAT IRRITATION (itching in throat) and EPISTAXIS (blood came out of nose when blew her nose) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   In February 2022, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Oct-2022, the patient experienced COVID-19 (tested positive for COVID). On an unknown date, the patient experienced ASTHENIA (After the booster, patient had weakness / still feels weakness, feels not so energetic), COUGH (had a little cough), THROAT IRRITATION (itching in throat), EPISTAXIS (blood came out of nose when blew her nose), BLOOD BLISTER (blisters in mouth, blisters on side of nose / The blister was like an open wound and has blood), IMMUNISATION REACTION (patient had a bad reaction), FEELING HOT (face was very hot, face felt warm) and PYREXIA (After the booster, patient had a little bit of fever/ slight fever). The patient was treated with DOXYCYCLINE at an unspecified dose and frequency and METHYLPREDNISOLONE at a dose of 4 milligram. At the time of the report, ASTHENIA (After the booster, patient had weakness / still feels weakness, feels not so energetic) and BLOOD BLISTER (blisters in mouth, blisters on side of nose / The blister was like an open wound and has blood) had not resolved and COVID-19 (tested positive for COVID), COUGH (had a little cough), THROAT IRRITATION (itching in throat), EPISTAXIS (blood came out of nose when blew her nose), IMMUNISATION REACTION (patient had a bad reaction), FEELING HOT (face was very hot, face felt warm) and PYREXIA (After the booster, patient had a little bit of fever/ slight fever) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 18-Oct-2022, SARS-CoV-2 test: (Positive) tested positive for COVID at home. On an unknown date, SARS-CoV-2 test: (Negative) at the doctors office, tested negative and (Positive) at the emergency, tested positive.   Concomitant medications details were not reported by the reporter.  Reportedly, patient stated the COVID-19 was weird.  It was reported that the doctor prescribed patient amoxicillin but did not take the amoxicillin.  Patient had blood in the swab of the home test kit.   Reportedly, at the emergency, checked patient lungs and heart, and everything was ok.