After her 2nd dose, her temperature maxed out at 101-102 degrees/she had fever that reach a temperature of 101 degree F; she had a headache; This is a spontaneous report received from a contactable reporter(s) (Physician) from medical information team. The reporter is the patient.  A 56 year-old female patient received bnt162b2 (BNT162B2), administration date 19Apr2021 (Lot number: EW0169) at the age of 56 years as dose 2, single for covid-19 immunisation. The patient's relevant medical history was not reported. There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose: 1st, Lot: ER8732, After her 1st dose she was fine), administration date: 28Mar2021, when the patient was 56 years old, for Covid-19 immunization, reaction(s): "she was fine". The following information was reported: PYREXIA (non-serious) with onset 2021, outcome "recovering", described as "After her 2nd dose, her temperature maxed out at 101-102 degrees/she had fever that reach a temperature of 101 degree F"; HEADACHE (non-serious) with onset 2021, outcome "recovering", described as "she had a headache". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of pyrexia, headache.   Additional information: Caller states that she is a Physician and she does have a current license, but she has not worked for the last 3 years. She is calling about the Pfizer Covid 19 vaccine, reporting on herself. States she had a fever of 105 about 18 hours after getting the vaccine. Her bones were also aching; she had a severe headache and thought she was going to die; she was very dizzy; almost fell, and had to lay down on the floor. States that the fever started about 14 hours after getting the vaccine; her temperature started at 101. She took Tylenol which didn't do anything, and her temperature ended up at 105 at about 24 hours after the vaccine. States that this was her booster dose. She doesn't think this was a typical response. States that after her 1st dose she was fine. It occurred within the same time frame as the side effects from her booster dose. States that she took Motrin and responded well. When she got the booster, she told the nurse about getting the fever after the 2nd dose and the nurse told her not take any Motrin because it could lower her response to the vaccine, and to only take Tylenol. Caller states that she tried to follow the nurse's instructions and she ended up with a fever of 105 degrees. She doesn't know if it's normal to have that high of a fever for a 57 year old woman. States that she did take Motrin at midnight last night. States that she tries not to take it because it hurts her stomach, but she took it at midnight because she was afraid she was going to wake up dying again. Caller states that she is just trying to figure out if the nurse gave her a super dose that she wasn't supposed to, or if there have been problems with the lot number she received, or if others have complained about these same side effects as well. She thought about switching to Moderna for the booster, but then thought maybe she wouldn't have as many problems if she stuck with the same Manufacturer. States that she hasn't had many people say anything about having side effects. Her brother said that some of the people he works with, their wives have been having problems; no further details provided. Her husband was fine after getting his booster. States that maybe the dose is higher for some people and they need to back down on it; maybe Pfizer needs to do more research on it. States that she took Tylenol when her temperature was 101 degrees, but it did nothing and her temperature continued to go up to 105. She took Motrin around 2:30pm and her fever went back down to 101 degrees. Then she took the Motrin again around midnight to make sure her fever didn't go back up. Caller clarifies that she took Kirkland brand Acetaminophen. States that the Lot number is hard to read; can't even see it with her glasses. Expiry: Aug2023 , Lot: 1KV1764, Barcode from the bottle: A38985NF11, UPC from the wrapper: 096619383245. States that there were many times when her children had high temperatures and she gave them Tylenol and their fever was still climbing, so she gave them Motrin. She does not have the product to provide the Lot/UPC/Expiry; states that her kids are 20 years old now, and this was when they were 18 months. States the severe headache as medically significant because it was so bad that she didn't know if she had a blood vessel that was bursting in her head. States the dizziness as medically significant because she could have fallen; she had to lay down on the floor until the dizziness passed. Description of complaint: States that the fever started about 14 hours after getting the vaccine; her temperature started at 101. She took Tylenol which didn't do anything, and her temperature ended up at 105 at about 24 hours after the vaccine. Caller clarifies that she took Kirkland brand Acetaminophen, 500mg tablets; she took 2 tablets. States that the Lot number is hard to read; can't even see it with her glasses. Expiry: Aug2023 Lot: 1KV1764 Barcode from the bottle: A38985NF11 UPC from the wrapper: 096619383245 Product strength and count size dispensed: 500mg tablets, 500 count bottle. States that there were many times when her children had high temperatures and she gave them Tylenol and their fever was still climbing, so she gave them Motrin. She does not have the product to provide the Lot/UPC/Expiry; states that her kids are 20 years old now, and this was when they were 18 months. PC#2 Description of complaint: Pfizer Covid 19 Vaccine- Caller states that she is just trying to figure out if the nurse gave her a super dose that she wasn't supposed to, or if there have been problems with the lot number she received, or if others have complained about these same side effects as well. when she wanted to get the booster dose, the nurse informed her that it is not recommended to take motrin for side effects of vaccine and in case she gets fever its better to decrease the temperature with a cold shower or wet cloth.  she did not take motrin and ended up having a fever with temperature of 105 degree F and felt better afterwards. she believes that this could have been prevented and wants to know if there is any Data in regards to no taking Motrin, or if it would decrease the effectiveness of vaccine. in the Prescribing Information, prophylactic antipyretics and other pain medication to prevent symptoms associated with study intervention administration were not permitted. However, if a participant was taking a medication for another condition, even if it may have antipyretic or pain-relieving properties, it was not be withheld prior to study vaccination. ACIP recommendation: Routine prophylactic administration of antipyretic or analgesic medications (e.g., acetaminophen, non-steroidal anti-inflammatory drugs) for the purpose of preventing post-vaccination symptoms is not recommended.  No follow-up attempts are possible. No further information is expected.