Patient's back shingles stirred up again/Shingles that were previously on her back, blistered up again; above the waistline on her right side, spot itchy/still felt itchy in that spot; Patient broke out in a rash all over her face/not really a rash, rather tiny pimples that were all over her face; Patient's psoriasis went full bloom, all over legs / psoriasis stayed for 6 months; This spontaneous case was reported by a patient and describes the occurrence of ACNE (Patient broke out in a rash all over her face/not really a rash, rather tiny pimples that were all over her face), PSORIASIS (Patient's psoriasis went full bloom, all over legs / psoriasis stayed for 6 months), HERPES ZOSTER (Patient's back shingles stirred up again/Shingles that were previously on her back, blistered up again) and PRURITUS (above the waistline on her right side, spot itchy/still felt itchy in that spot) in a 76-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     No Medical History information was reported.    On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced ACNE (Patient broke out in a rash all over her face/not really a rash, rather tiny pimples that were all over her face), PSORIASIS (Patient's psoriasis went full bloom, all over legs / psoriasis stayed for 6 months), HERPES ZOSTER (Patient's back shingles stirred up again/Shingles that were previously on her back, blistered up again) and PRURITUS (above the waistline on her right side, spot itchy/still felt itchy in that spot). At the time of the report, ACNE (Patient broke out in a rash all over her face/not really a rash, rather tiny pimples that were all over her face), PSORIASIS (Patient's psoriasis went full bloom, all over legs / psoriasis stayed for 6 months), HERPES ZOSTER (Patient's back shingles stirred up again/Shingles that were previously on her back, blistered up again) and PRURITUS (above the waistline on her right side, spot itchy/still felt itchy in that spot) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       No concomitant medication information was provided.  Patient had received one Moderna Covid-19 vaccine dose in 12-December, but was not sure of the year, whether it was 2020 or 2021.  The patient was told by her physician to not to take the second dose of the vaccine  It was reported that after four days from the day of Moderna vaccination, the patient had rashes all over the face/tiny pimples which lasted for two days. It was reported that after four days from the day of Moderna vaccination, the psoriasis condition was in full bloom all over the legs and continued for six months (psoriasis would be there one day, and then started to go away). The patient could still see the psoriasis scars. It was reported that after four days from the day of Moderna vaccination, the patient's shingles that were previously on back, blistered up again and also the spot above the waistline on her right side felt itchy, and this condition subsided two or three days later and it was gone. The pimples on face also went away after a while. At that time, the patient did not receive the second dose of the vaccine.  The patient reported that it was a rare scenario that this happened as she had never been sick before.  The patient went to different pharmacies and was told that she could not receive other COVID-19 Vaccines like the Pfizer COVID-19 vaccine. The patient was informed that when the new vaccine came out, she was told to get her second dose.  No treatment medications were reported.