she experienced muscle and joint pain./there is a stabbing knee pain when walking and back hip's nerve pain on right side leg was worst.; she experienced muscle and joint pain./there is a stabbing knee pain when walking and back hip's nerve pain on right side leg was worst.; she experienced muscle and joint pain./there is a stabbing knee pain when walking and back hip's nerve pain on right side leg was worst.; sciatica that runs down her hip and leg; walks with a limp; Caller also mentioned that after she received the first dose her pain level has worsened. It went from 5 to 10 levels of pain.; couldn't bear weight on her right leg; numbness on left side of knee; severe sensitivity to touch on top to the side of the knee; This is a spontaneous report received from a contactable consumer reported for patient. A 53-years-old female patient received first dose BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: ER2613, Expiration date: unknown) via an unspecified route of administration, administered in left arm on 19Mar2021 (age at vaccination was 53 years) as dose 1, single for COVID-19 immunization. The patient's medical history included high blood pressure, hypoglycemia (that was controlled by diet), mood swings, chronic sinusitis (she gets several sinus infections every year, had three good ones before she got the vaccine), had a back condition and sciatica and rheumatoid arthritis (she saw a Rheumatologist last year who seemed to think the patient had Rheumatoid Arthritis). The patient's family history included cancer runned on both sides, her dad had lung cancer three times, mom did not have cancer but most of her relatives did, diabetes both mom and dad, hypertension-mom, macular degeneration on mom's side, terrible bones on dad's side particularly arthritis, dad had both osteoarthritis and rheumatoid arthritis, sister had rheumatoid arthritis, doctor just ordered more bloodwork to see if inflammation markers are still elevated and if they are have to go for more tests. Concomitant medications included naproxen taken for back pain from an unspecified start date and ongoing (she had been taking for more than 5 years), tizanidine hydrochloride (ZANAFLEX) taken for back flare from Dec2020 and ongoing (started taking in December after she shoveled snow she shouldn't have shoveled. She was taking only when she had a back flare at night, but now she takes it twice a day due to the pain. She reported that her nerve pain was in left leg before shoveling and then switched to the right leg after the shoveling. She stated that physical therapy that she was ordered for her back and leg, aggravated her right hip and right knee pain. She stated all her pain was on the right side now. Prior to taking the COVID vaccine, she only took one of these at night, but since the vaccine, she takes this twice a day now), gabapentin (NEURONTIN) taken for nerve pain from an unspecified start date and ongoing (been taking more than 5 years. When the pain was really bad, she would take 3 pills at a time; talked to primary about increasing to 3 times per day, and PCP to said only if caller absolutely has to), tizanidine (TIZANIDINE) taken for muscle relaxant, start and stop date were not reported and oxycodone hydrochloride, oxycodone terephthalate, paracetamol (PERCOCET) taken for extreme pain, start and stop date were not reported. The patient wanted to know if these will interfere with the vaccine. There was no history of any previous immunization with the Pfizer vaccine considered as suspect. No additional vaccines were administered on same date of the Pfizer Suspect. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Since the first vaccine, on 19Mar2021 around midnight, the patient's joints and muscle pain had gotten worse. Within 24 hrs pain level jumped up. There was a stabbing knee pain when walking and back hip's nerve pain on right side leg was worst. She had a back condition and sciatica that runs down her hip and leg and by midnight on the day she got her vaccine, her normal pain level which was 4 or 5, shot up to 10 and stayed there for almost a week. The knee pain was so bad after vaccine that she went to a knee specialist who seemed to think that it was from nerves in her back. She felt like someone was taking a knife and stabbing through the middle of the knee. It was better after she took the medicine. It felt like a lot of it was nerve pain, numbness on left side of knee and severe sensitivity to touch on top to the side of the knee, the stabbing pain came when she walked on it. She could barely get up or down the stairs. She was in agony, dying and couldn't bear any weight on her right leg at all. She stated that now she could walk but walked with a limp. She stated that since then, she had been placed on Percocet and a muscle relaxer and wanted to know if it was safe for her to get the second shot now that she had these two additional medications. She reported that her back pain has been getting worse since shoveling that snow in December. She stated that those were conditions that she had prior to the vaccine, they just have gotten considerably worse, since getting the vaccine. The patient had x-rays of the hip and knee and that showed that she had arthritis in her hip, knee and back on an unspecified date. Also in her right knee was what the knee specialist thought was a bone spur that wasn't floating around, it was still attached. The specialist didn't think that anything that showed up on the x-ray did not seem bad enough to be causing the pain she was feeling that's why he thought it was coming from the patient's back. Her rheumatologist just ordered more bloodwork to see if inflammation markers are still elevated and if they have to go for more tests. The patient added that the hip and knee specialist seemed to think that she could possible have a torn meniscus in her knee and ordered MRIs which she has not gotten done yet. Her spine MRI was on Monday and then the hip and knee were on Wednesday. The events did not require a visit to Emergency Room. The events required a visit to Physician Office. The patient stated that that was the first time she was calling because every other doctor she saw said it was not related to the Pfizer COVID-19 vaccine, even though she saw muscle and joint pain listed as possible side effects to the vaccine. She stated that she also saw on the news that people can take Tylenol after they get the vaccine to prevent possible pain, but that people should not take Tylenol it before getting the vaccine, which made her wonder about her medications and was it ok to take those before she goes to get her second shot, which was scheduled that day in an hour. She was due to take her medications. The patient was due for the second dose that afternoon. She said that before she received the first dose she had back pain and joint pain and she's been taking Percocet for extreme pain. She mentioned that after she received the first dose her pain level has worsened. It went from 5 to 10 levels of pain. She said that she took Tizanidine as a muscle relaxant. She was due to have her second Pfizer COVID-19 vaccine later this afternoon. She said that she was worried about taking the second dose this afternoon. She asked if she was safe to get the second dose of the vaccine. The outcome of the events sciatica, gait disturbance and condition aggravated was unknown. The outcome of the other events was not resolved.  No follow-up attempts are needed. No further information is expected.