Passed a very large mucous plug; Vomiting; Nose was running; Headache; When she woke up, her throat hurt and she could barely swallow. It was getting worse and worse; Fever; By the second day of antibiotics, she started feeling like whatever infection she had was drying out,; Felt really tired; Throat hurt and could barely swallow; Throat hurt and could barely swallow; Body ache; Chest and ribs hurt from coughing; Chest and ribs hurt from coughing; Coughing; like the shot of death for her. It was hard and hit like nothing had ever been hit before.; This is a spontaneous report from a Pfizer-sponsored program from a contactable consumer or other non hcp.  A 54-years-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection. Lot number: unknown), via an unspecified route of administration, on 08Jun2021 at 10:00 (at the age of 54-years-old) as dose 1, single for COVID-19 immunization. Medical history included had vomiting that has been going on and was an underlying issue and gastric irrigation. The patient's concomitant medications were not reported. The patient previously took omeprazole for gastric ulcer and experienced no reaction on previous exposure to drug, hydroxyzine arrow for vomiting and experienced no reaction on previous exposure to drug, famotidine acid reducer for gastritis and experienced no reaction on previous exposure to drug, ondansetron for vomiting and experienced no reaction on previous exposure to drug. The patient experienced by the second day of antibiotics, she started feeling like whatever infection she had was drying out, like the shot of death for her, it was hard and hit like nothing had ever been hit before, felt really tired, throat hurt and could barely swallow, body ache, chest and ribs hurt from coughing, coughing, passed a very large mucous plug, when she woke up, her throat hurt and she could barely swallow. it was getting worse and worse, fever, vomiting, nose was running, headache. Patient knows her immune system was down and patient was on a whole lot of medication right now. Patient had been taking all of these medications for about a month and a half. Had been going through a lot of tests. With vomiting, it could make the mucosal lining thin, which could be a reason for the sore throat. What ever was going on in belly, patient did not know what it was. Something was in there, and it hurts. Patient going for a CT scan. Her NCLEX was scheduled for 04Jul2021 and it was one day that week. Patient was otherwise super healthy and rides bikes and runs. Patient went to the doctor because patient had some underlying issues and was on Z-pack right now. Patient got some antibiotics, Z-Pack, patient really felt like that was what she needed for some kind of infection in her body. On third day of the z-pack and patient was feeling better. Patient had no history of all previous immunization with the Pfizer vaccine considered as suspect. No additional vaccines administered on same date of the Pfizer suspect. Patient had no adverse event prior vaccinations, was going through all of the vaccines for nursing school and never had a reaction. Patient had no medical history (including any illness at time of vaccination). Patient had no family medical history relevant to adverse event. Patient did not perform relevant tests. The patient previously took omeprazole, patient had some type of mass in abdomen. Was very painful and can vomit anywhere. The most was 17 times in a day and was projectile. Had helped a little bit. Hydroxyzine can be used for an anti emetic. Got excited a lot when body was stressed, had to take when eczema was flaring. It was helping. Famotidine another gastric medication and taken it at night. Ondansetron Generic form of Zofran. Onset of adverse event was 08Jun2021. On last Tuesday at 10:00, patient got the injection and within 2 hours, patient started to feel really tired. Rides 60 miles a day minimum on bike and couldn't even get to 30 or forty miles. Patient lied down for a nap and slept for 2 hours. When patient woke up, throat hurt and patient could barely swallow. It was getting worse and worse. The Fatigue set in and nose was running, patient had a headache and low grade fever. Today was first day of feeling better and was able to get out of bed. Patient was not exercising yet, though. had no more body aches, chest, ribs and everything were hurting from all of the coughing. Had a large amount of coughing and passed a humungous, very large mucous plug. From her throat, all the way down to ear, it felt like something had just popped. By the second day of antibiotics, patient started feeling like whatever infection had was drying out, today actually. Patient was going to study now and can think again. Patient can think clearly now, everything was very foggy. Fever was very low grade and was less than 100.4. Occurred 4 hours after administration. Patient went to the doctor for some lab test. Patient had lots of gastric irrigation and had been taking medication. Patient was waiting for an endoscopy. Had vomiting that has been going on and is an underlying issue. Indication: patient did not initially want to get the vaccine. Patient had some underlying things going on and was waiting for tests. Patient was worried about vomiting and stuff patient had been through would affect body. Patient was going to wait until passed NCLEX and was started in the hospital. Patient was going to get vaccinated. It was like the shot of death for her. It was hard and hit like nothing had ever been hit before. Patient did not visit to emergency room or physician office. The patient underwent lab test and procedure which include, endoscopy on Jun2021 result was unknown. Patient had fever less than 100.4 on 08Jun2021. Streptococcus test was negative on Jun2021. Therapeutic measures were taken as a result of by the second day of antibiotics, she started feeling like whatever infection she had was drying out, vomiting which were some antibiotics, Z-pack. The outcome of the event pain recovered, event vomiting not recovered, Infection, pyrexia, rhinorrhea and headache were recovering and rest of the events were unknown.   Information about Lot/Batch number has been requested.