Tooth ache; Cold sore; sunburn; This is a spontaneous report received from a contactable reporter(s) (Nurse) from medical information team. The reporter is the patient.  A 61-year-old female patient received BNT162b2 (BNT162B2), as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history was not reported. Concomitant medication(s) included: ASPIRIN [ACETYLSALICYLIC ACID]. Vaccination history included: Covid-19 vaccine (Primary Immunization series complete;  unknown manufacturer), for COVID-19 immunization. The following information was reported: ORAL HERPES (non-serious) with onset 24Jul2022, outcome "unknown", described as "Cold sore"; SUNBURN (non-serious) with onset 24Jul2022, outcome "unknown"; TOOTHACHE (non-serious) with onset 25Jul2022, outcome "unknown", described as "Tooth ache". Therapeutic measures were taken as a result of sunburn, toothache, oral herpes.  Additional information: Attempted transfer from (Name withheld) in Pfizer USMI GRACE: INT-00718485. Caller is scheduled to receive second booster dose of the Pfizer BioNTech Covid 19 today, 25Jul2022. Yesterday, 24Jul2022, caller spent time in sun and got a little bit of sunburn. Caller took two Valtrex prophylactically last night, 24Jul2022 to prevent a cold sore due to being out in the sun. Also, took daily Aspirin today, 25Jul2022. Took two Advil this morning, 25Jul2022 for a little bit of a tooth ache. Wanted to know how Valtrex, Aspirin and Advil impact effectiveness of Pfizer BioNTech Covid 19 Vaccine? Takes aspirin everyday and has done so for several years. Transfer agent provided information to caller regarding caller's question prior to attempted transfer to Agent. Caller disconnected while agent was providing Agent with information. Question was Caller spent time in the sun yesterday and got a little sunburn. She took two Valtrex prophylactically last night to prevent a cold sore due to the sun. Can the Valtrex impact the effectiveness of the vaccine. She was scheduled to get her second booster dose today. You haven't had any problems with it. So Pfizer was okay for Valtrex if people take it every day, its kind of not coming up as anything. She also takes daily aspirin and 2 Advil this morning for a little bit of a tooth that is bothering her. If I take an NSAID and aspirin is that impacting in any way with the vaccine. She has taken daily aspirin for several years. 61 years old. Transferred caller to (Name withheld). NTID # (ID withheld) Reportum #TGZSJ7B6 Caller disconnected during warm transfer. Question was She also takes daily aspirin and 2 Advil this morning for a little bit of a tooth that is bothering her at 6 this morning. If I take an NSAID and aspirin is that impacting in any way with the vaccine. So what I'm hearing from you, if its an adverse event, then I should like not make sure I don't take an Advil before I go for the thing also because that is what the CDC is recommending and therefore I should cancel my appointment. Callback made at 2:35pm EST. Caller asks what impact the allowed medications made on the vaccine in the clinical trial. Question was I would think that Pfizer would say that with the way this vaccine came out, in the beginning they wouldn't know how anything was really going to interact with the vaccine so its kind of we don't have the information yet but now we're two years in I'd like to think there would be some information on true adverse events if you were taking them or ineffectiveness of the vaccine but the reason I know thats not happening is because nobody ever asked me what I'm taking when I go get my vaccine. So unless your really having a adverse, true adverse event thats reported because your you know having a rash or something happen, I don't know how they're getting, would be getting that data from scientists in the lab but, that could draw certain conclusions on these drugs. But these are such common drugs taken by people. Upon callback caller states the information shared was not helpful. She wants to know what impact the allowed medications made on the vaccine and if it is safe to take them. That's what people want to know.  Request Name: REQ-866765. Question was I'm happy I called you and got, there's a live person there to answer the call and answer my questions. Thank you so much.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.