Felt lethargic; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 70-year-old female patient received BNT162b2 (BNT162B2), on 05Apr2021 as dose 2, single (Lot number: EW0151) at the age of 69 years for covid-19 immunisation. The patient's relevant medical history included: "Ductile carcinoma", start date: 2021 (unspecified if ongoing), notes: 2021 dx with ductile carcinoma of the left breast in site 2. There were no concomitant medications. Vaccination history included: BNT162b2 (Dose: 01, Lot: EP7534), administration date: 15Mar2021, when the patient was 69-year-old, for COVID-19 Immunization, reaction(s): "Felt lethargic".  The following information was reported: LETHARGY (non-serious) with onset 2021, outcome "unknown", described as "Felt lethargic".  Additional information: Warm transfer from (name withheld) Pfizer. Agent has a patient on the line calling about the Pfizer Bivalent Booster. She received it on 10Sep2022, 30mcg/0.3mL and that evening of getting the vaccine she had itching on her right arm where the booster was administered. Then on Sunday 11Sep2022, her right arm developed a rash and hives. She contacted her HCP who told her to take Benadryl. Caller confirms above information and adds that it went form her right arm to her left arm she had bumps and severe itching. She reported it to the pharmacy who administered the vaccine and read about signs of allergic reactions on Pfizer's information. She had rash, hives, itching and she got the vaccine at the stop and shop pharmacy. Her HCP told her to take 50mg of Benadryl and as needed and another thing she is doing is an antiseptic bug spray, she didn't have calamine in her house so she is using both the Benadryl and the spray. Caller reports that the itching was really severe, she had gone to the dermatologist which was unrelated to this, but she had the dermatologist looked at her arms and the dermatologist is in the process of prescribing a topical cream to use to help with the itchiness. Caller states that it has gotten a little better, but she still has a bit of itchiness on the back of her forearm that is bothering her. Indication: She was attending a 50 plus high school reunion and the new booster was available and everyone involved with this was running to get it. The reunion is in a tent outside, but everyone is doing it. Plus, in her community 55 and over covid goes around she masks up and took the vaccine for the other people for the reunion. Medical Conditions: Caller reports that in 2021, 2021 dx with ductile carcinoma of the left breast in site 2. She completed 6 weeks of radiation followed by a year later she started a 5 year regimen of tamoxifen. Attempted clarification on treatment used for the bumps and itchiness and caller states that when she contacted her HCP, they suggested 50mg of Benadryl and an over the counter cortisone cream and the dermatologist yesterday is prescribing something else. Attempted clarification on what that is and caller states she does not know she has not picked it up from the pharmacy yet. Prior Vaccinations (within 4 weeks): No. AE(s) following prior vaccinations: Caller reports she had extreme soreness of her right arm after the 4th dose, the 2nd booster. And she felt lethargic after the first 2 rounds of the vaccine but nothing earth shattering. She also had the singles shots a year ago affect her for 24 hours. NDC, lot and expiry: unknown. Patient's Medical History: No. Family Medical History: mother passed away from metastasis of melanoma and her father passed away at 100 from congestive heart failure. Relevant Tests: No. Caller then asks how long will this reaction last? She has never had an allergic reaction before. She told her pharmacy and was told to report this to # which she did too.  No follow-up attempts are possible. No further information is expected.