Severe headache; headache was very bad; it was so much that I am scared to take the second dose; Muscle pain; joint pain; This is a spontaneous report from a contactable nurse (patient). A 55-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/lot number: EK5730, Expiry Date: 31Mar2021) via an unspecified route of administration on 18Dec2020 at single dose to prevent Covid 19, to get antibodies; folic acid via an unspecified route of administration from an unspecified date at 1 mg, daily for Thalassaemia minor; levothyroxine sodium via an unspecified route of administration from an unspecified date at 50 mg, daily for an unspecified indication; zinc oxide via an unspecified route of administration from an unspecified date at 50 mg, daily for an unspecified indication; nifedipine (NIFEDIPINE XL) via an unspecified route of administration from an unspecified date at 60 mg, daily for blood pressure high; valsartan via an unspecified route of administration from an unspecified date at 80 mg, daily (one morning one in the evening) for blood pressure high; paroxetine via an unspecified route of administration from an unspecified date at 10 mg, daily for an unspecified indication; cyanocobalamin (VIT B12) via an unspecified route of administration from an unspecified date at 1000 mg, daily for an unspecified indication; ascorbic acid (VIT C) via an unspecified route of administration from an unspecified date at 1000 daily for an unspecified indication; acetylsalicylic acid (ASPIRIN) via an unspecified route of administration from an unspecified date at 81 mg (once in week or every other day ) for an unspecified indication. Medical history included hyperthyroidism; anxiety; Thalassaemia minor; Blood pressure high; patient was diagnosed with Covid-19 earlier, she stated she was a survivor, she recovered on 06Apr2020, she was sick on 21Mar2020 and she was ruled out positive on 25Mar2020 when they bought out the test first time, she said she might have been positive before but they did not have the test. The patient's concomitant medications were not reported. Patient stated she took the vaccination (Pfizer Covid 19 vaccine) in the hospital, she worked there she was a nurse, and she got the side effect, she got severe headache. She had headache but her mistake she did not take Tylenol that time but it got eased after may be 5 hours but the problem was (statement incomplete), and then she started having muscle pain, joint pain and that was okay but headache was very bad, out of all this. Her question was  she was a survivor Covid-19 but this one took on her, the headache and she was on blood pressure medications too (further not appropriately paraphrased and clarified hence captured as unspecified medications) so she didn't know what were the ingredients which caused her such a severe headache. So now her question was that was it okay for her to take the second dose after 3 weeks. The start date of headache was not even half an hour within 15 minutes of taking vaccine. For headache, patient was okay now, that time it was so much that she was scared to take the second dose, the booster dose, so that was why she want to check with them that it was okay or not because she had severe headache. After 5 hour it was improved without taking anything, it subsided on it's on. No treatment received. The action taken in response to the events for folic acid, levothyroxine sodium, zinc oxide was unknown. The outcome of the event Headache was recovered on 18Dec2020, of the other events was recovering.   Pfizer is a marketing authorization holder of [folic acid, levothyroxine sodium, zinc oxide] in the country of incidence or the country where the product was purchased (if different). This may be a duplicate report if another marketing authorization holder of [folic acid, levothyroxine sodium, zinc oxide] has submitted the same report to the regulatory authorities.