burning sensation got worse and then got worse from there; Burning sensation; Inflammation; This is a spontaneous report from a contactable consumer (Patient's husband). A 55-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, solution for injection, Batch/Lot Number: EN6205), dose 2 via an unspecified route of administration, administered in left arm on 27Feb2021 at 10:00 (age at vaccination: 55-year-old) as a single dose for COVID-19 immunisation. The patient medical history included allergic to hydrocodeine since 9 or 10 years, from an unspecified date and was still ongoing at the time of report. The patient had no concomitant medications. The patient had no family medical history relevant to adverse events. The patient previously took first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, solution for injection, Lot Number: EL9269) on 01Feb2021, in left arm for COVID-19 immunisation. The patient received second dose of COVID-19 vaccine 26 days after receiving the first dose of vaccine. The patient did not receive any additional vaccines. The patient did not have any prior Vaccinations within 4 weeks nor adverse events following prior vaccinations. On an unspecified date in 2021, the patient experienced inflammation, on 27Feb2021, patient had burning sensation and the following day, on 28Feb2021, patient burning sensation got worse and then got worse from there. She had inflammation like a burning sensation in her left hand and half part of the body from her shoulder to her left leg. The patient reported that after a week of experiencing the burning sensation, the patient went to her doctor and the patient's doctor said it was normal. The patient's burning sensation was not getting any better, so the patient went to another doctor who prescribed medicine, but the burning sensation did not get any better. The patient took 3 medicines from the doctor but it did not help. The patient received treatment with Tylenol Extra strength, Diclofenac Potassium, Tramadol and Aspirin. The doctor gave her medications to take as follows: Bayer aspirin occasionally and vaccine supplemental Form. It was clarified that the doctor prescribed two medications for the patient and that over-the-counter Tylenol was recommended to take in addition to the prescription products. The patient received the COVID 19, because they called and they said just go ahead and come in. Investigation Assessment was not reported. Vaccination Facility type was reported as hospital. The patient had not done any relevant tests. It was reported that the patient's doctor is having her do therapy next week. The patients husband was unsure of what to do for the patient since she was still experiencing the burning sensation. Tylenol, diclofenac, tramadol, and aspirin did not help burning sensation experienced by the patient. Adverse events did not require a visit to Emergency Room but visited physician office for burning sensation. The clinical outcome of event inflammation and burning sensation got worse and, then got worse from there was unknown but burning sensation was reported as not recovered.  No follow-up attempts are possible. No further information is expected.