In 2021 she had nausea,vomiting,waekness,cough,fever; In 2021 she had nausea,vomiting,waekness,cough,fever; In 2021 she had nausea,vomiting,waekness,cough,fever; In 2021 she had nausea,vomiting,waekness,cough,fever; In 2021 she had nausea,vomiting,waekness,cough,fever; injection site warm to the touch; injection site swelling; injection site pain; Restlessness; This spontaneous case was reported by a physician and describes the occurrence of ASTHENIA (In 2021 she had nausea,vomiting,waekness,cough,fever), RESTLESSNESS (Restlessness), VACCINATION SITE WARMTH (injection site warm to the touch), VACCINATION SITE SWELLING (injection site swelling) and VACCINATION SITE PAIN (injection site pain) in a 55-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) for Rheumatoid arthritis.    The patient's past medical history included Heart attack, Coronary artery occlusion, COVID-19 and Stent placement. Previously administered products included for Blood pressure high: hydrochlorothiazide; for an unreported indication: Non steroidal anti inflammatory drug and ASPIRIN (E.C.). Concurrent medical conditions included Diabetes, Rheumatoid arthritis and Allergy (Aspirin allergies manifested by difficulty breathing, hives, and eye swelling). Concomitant products included CETIRIZINE for Allergy, LISINOPRIL for Blood pressure high, SEMAGLUTIDE (OZEMPIC) for Diabetes, IBUPROFEN for Pain, VITAMIN D3 for Vitamin supplementation, ROSUVASTATIN for an unknown indication.   On 24-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) 40 milligram per millilitre every two weeks. In March 2021, the patient experienced RESTLESSNESS (Restlessness). On 24-Mar-2021, the patient experienced VACCINATION SITE WARMTH (injection site warm to the touch), VACCINATION SITE SWELLING (injection site swelling) and VACCINATION SITE PAIN (injection site pain). On an unknown date, the patient experienced ASTHENIA (In 2021 she had nausea,vomiting,waekness,cough,fever), NAUSEA (In 2021 she had nausea,vomiting,waekness,cough,fever), PYREXIA (In 2021 she had nausea,vomiting,waekness,cough,fever), COUGH (In 2021 she had nausea,vomiting,waekness,cough,fever) and VOMITING (In 2021 she had nausea,vomiting,waekness,cough,fever). At the time of the report, ASTHENIA (In 2021 she had nausea,vomiting,waekness,cough,fever) and COUGH (In 2021 she had nausea,vomiting,waekness,cough,fever) had not resolved and RESTLESSNESS (Restlessness), VACCINATION SITE WARMTH (injection site warm to the touch), VACCINATION SITE SWELLING (injection site swelling), VACCINATION SITE PAIN (injection site pain), NAUSEA (In 2021 she had nausea,vomiting,waekness,cough,fever), PYREXIA (In 2021 she had nausea,vomiting,waekness,cough,fever) and VOMITING (In 2021 she had nausea,vomiting,waekness,cough,fever) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In March 2021, Blood test: unknown unknown. In March 2021, Electrocardiogram: unknown unknown. In March 2021, SARS-CoV-2 test: positive (Positive) positive. In March 2021, X-ray: unknown unknown. On an unknown date, Blood glucose: unkown unknown.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   The patient was treated with Metoprolol, Prasugrel, and Ativan