Pain/aches; Chills; Low grade fever; This spontaneous case was reported by a consumer and describes the occurrence of PAIN (Pain/aches), CHILLS (Chills) and PYREXIA (Low grade fever) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 001CZIA) for COVID-19 vaccination.     The patient's past medical history included Multiple sclerosis in December 1992. Concurrent medical conditions included Sulfonamide allergy and Drug allergy (Povidone Iodine (Rash)). Concomitant products included BUPROPION, CITALOPRAM, OXYBUTYNIN, MAGNESIUM OXIDE, ESTRADIOL, VITAMIN D NOS and VALACYCLOVIR [VALACICLOVIR] for an unknown indication.   On 01-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 29-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 29-Apr-2021, the patient experienced PAIN (Pain/aches), CHILLS (Chills) and PYREXIA (Low grade fever). The patient was treated with IBUPROFEN (ADVIL [IBUPROFEN]) for Fever and Ache, at a dose of 1 dosage form and PARACETAMOL (TYLENOL) for Fever and Ache, at a dose of 1 dosage form. On 02-May-2021, PAIN (Pain/aches) and CHILLS (Chills) had resolved. At the time of the report, PYREXIA (Low grade fever) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 17-May-2021, Pyrexia: 101 (Low) low grade. On 17-May-2021, Ultrasound bladder: noncontributory for microscopic hematuria (Negative) Noncontributory for microscopic hematuria.. On 17-May-2021, Ultrasound kidney: noncontributory for microscopic hematuria. (Negative) Noncontributory for microscopic hematuria.. On 20-May-2021, AST/ALT ratio: 19 (normal) (Ref range:12-45u/l). On 20-May-2021, Alanine aminotransferase: 19 (normal) (Ref range:2-50u/l). On 20-May-2021, Albumin globulin ratio: 0.9 (Inconclusive) 0.9 g/dL. On 20-May-2021, Anion gap: 9.0 (normal) (Ref range:7.0-16.0). On 20-May-2021, Basophil count: 0.06 (normal) (Ref range:0.00-0.12K/uL) and 0.90 (normal) (Ref range:0.00-1.80%). On 20-May-2021, Blood albumin: 3.8 (normal) (Ref range:3.2-4.9g/dl). On 20-May-2021, Blood alkaline phosphatase: 136 (High) (Ref range:30-99u/l). On 20-May-2021, Blood bilirubin: 0.2 (normal) (Ref range:0.1-1.5mg/dl). On 20-May-2021, Blood calcium: 9.9 (normal) (Ref range:8.5-10.5mg/dl). On 20-May-2021, Blood chloride: 98 (normal) (Ref range:96-112mmol/L). On 20-May-2021, Blood creatinine: 0.66 (normal) (Ref range:0.50-1.40mg/dL). On 20-May-2021, Blood glucose: 87 (normal) (Ref range:65-99mg.dL). On 20-May-2021, Blood lactic acid: 0.8 (normal) 0.8 (ref range : 0.5-2.0 mmol/L). On 20-May-2021, Blood potassium: 4.4 (normal) (Ref range:3.6-5.5mmol/L). On 20-May-2021, Blood pressure measurement: 135/69 (Inconclusive) BP 135/69. On 20-May-2021, Blood sodium: 132 (Low) (Ref range:135-145mmol/L). On 20-May-2021, Blood urea: 18 (normal) (Ref range:8-22mg/dL). On 20-May-2021, Body temperature: 37.2 (Inconclusive) temp 37.2 degree celsius (99 degree F) (Temporal). On 20-May-2021, Carbon dioxide: 25 (normal) (Ref range:20-33mmol/L. On 20-May-2021, Chest X-ray: no acute cardiopulmonary disease (Negative) No acute cardiopulmonary disease (Portable 1 view). On 20-May-2021, Computerised tomogram thorax: no pulmonary embolus appreciated (Negative) No pulmonary embolus appreciated.. On 20-May-2021, Eosinophil count: 0.18 (normal) Absolute  (Ref range:0.00-0.51k/uL) and 2.60 (normal) (Ref range:0.00-6.90%). On 20-May-2021, Fibrin D dimer: elevated (High) elevated. On 20-May-2021, Globulin: 4.3 (High) (Ref range:1.9-3.5g/dl). On 20-May-2021, Glomerular filtration rate: >60 (Inconclusive) (Ref range:>60ml/min/1.73m2). On 20-May-2021, Haematocrit: 35.3 (Low) (Ref range:37.0-47.0%). On 20-May-2021, Haemoglobin: 11.0 (Low) (Ref range:12.0-16.0g/dL). On 20-May-2021, Heart rate: 82 (Inconclusive) pulse 82. On 20-May-2021, Lymphocyte count: 1.60 (normal) (Ref.Range- - 1.00-4.80K/uL) and 23.50 (normal) (Ref range:22.00-41.00%). On 20-May-2021, Mean cell haemoglobin: 29.7 (normal) (Ref range:27.0-33.0pg). On 20-May-2021, Mean cell haemoglobin concentration: 31.2 (Low) (Ref range:33.6-35.0g/dL). On 20-May-2021, Mean cell volume: 95.4 (normal) (Ref range:81.4-97.8fL). On 20-May-2021, Mean platelet volume: 9.6 (normal) (Ref range:9.0-12.9fL). On 20-May-2021, Monocyte count: 7.80 (normal) (Ref range:0.00-13.40%). On 20-May-2021, Mononucleosis heterophile test positive: 0.53 (normal) (Ref range:0.00-0.85K/uL). On 20-May-2021, Neutrophil count: 4.43 (normal) (Ref range:2.00-7.15K/uL) and 65.20 (normal) (Ref range:44.00-72.00%). On 20-May-2021, Oxygen saturation: 97 percent (Inconclusive) spo2 97 %. On 20-May-2021, Platelet count: 336 (normal) (Ref range:164-446K/uL). On 20-May-2021, Protein total normal: 8.1 (normal) (Ref range:6.08.2g/dl). On 20-May-2021, Pyrexia: 101 (Low) low grade. On 20-May-2021, Red blood cell count: 3.70 (Low) 3.70(L) (Ref range:4.20-5.40 M/uL). On 20-May-2021, Red blood cell nucleated morphology: 0.00 (Inconclusive) (Ref range:/100WBC). On 20-May-2021, Red cell distribution width: 43.0 (normal) (Ref range:35.9-50.0fL). On 20-May-2021, Respiratory rate: 18 (Inconclusive) resp18. On 20-May-2021, White blood cell count: 6.8 (Inconclusive) 6.8 (Ref range:4.8-10.8 K/uL). On an unknown date, COVID-19: negative (Negative) Negative.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Patient underwent lab tests of NRBC, Manual diff status, Peripheral smear, Plt Estimation, and RBC monography.  Patient have remote history of surgery in the presence of tachycardia.  Action taken with mRNA-1273 in response to the event was not applicable.   This case was linked to MOD-2021-120176 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 21-Jun-2021: Updated Patient's historical condition along with allergies, Lab data, Concomitant and treatment medications, and also Events.