Left arm  axillary swelling; Painful deep lymph node; This spontaneous case was reported by a health care professional and describes the occurrence of PERIPHERAL SWELLING (Left arm  axillary swelling) and LYMPHADENOPATHY (Painful deep lymph node) in a 47-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 011J20A and 004M20A) for COVID-19 vaccination.     The patient's past medical history included Swelling (Axillary swelling in the arm where he receive the injection) on 20-Jan-2021, Chills and Fever. Concurrent medical conditions included Drug allergy (allergic to tramadol) and Hypertension since 2014. Concomitant products included CHLORDIAZEPOXIDE HYDROCHLORIDE, CLIDINIUM BROMIDE (LIBRAX [CHLORDIAZEPOXIDE HYDROCHLORIDE;CLIDINIUM BROMIDE]) for Anxiety.   On 24-Dec-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 23-Jan-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 30-Dec-2020, the patient experienced PERIPHERAL SWELLING (Left arm  axillary swelling) and LYMPHADENOPATHY (Painful deep lymph node). The patient was treated with COLECALCIFEROL (VITAMIN D [COLECALCIFEROL]) (oral) in May 2020 for Supplementation therapy, at a dose of 400 mg once a day and VITAMIN C [ASCORBIC ACID] (oral) in May 2020 for Supplementation therapy, at a dose of 500 mg once a day. On 20-Jan-2021, PERIPHERAL SWELLING (Left arm  axillary swelling) had resolved with sequelae. At the time of the report, LYMPHADENOPATHY (Painful deep lymph node) outcome was unknown. Not Provided    DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Alanine aminotransferase normal (10.00-44.00): 17.40 17.40. On an unknown date, Albumin globulin ratio (0.70-2.30): 2.18 2.18. On an unknown date, Anion gap (5.00-25.00): 17.66 17.66. On an unknown date, Aspartate aminotransferase decreased (10.00-34.00): 16.30 16.30. On an unknown date, Basophil count (0.00-0.04 %): 0.03 % 0.03 and 0.3 % 0.3. On an unknown date, Blood albumin (3.50-5.00 g/dL): 5.10 g/dL 5.10. On an unknown date, Blood alkaline phosphatase (32.00-122.00 U/L): 60.00 U/L 60.00. On an unknown date, Blood bilirubin (0.20-1.00 mg/dl): 1.17 mg/dl 1.17. On an unknown date, Blood calcium (8.50-10.50 mg/dl): 10.16 mg/dl 10.16. On an unknown date, Blood chloride (98.00-110.00 10 thousand per litre): 100.70 10 thousand per litre 100.70. On an unknown date, Blood creatinine (0.50-1.20 mg/dl): 0.99 mg/dl 0.99. On an unknown date, Blood potassium (3.50-5.30 10 thousand per litre): 4.76 10 thousand per litre 4.76. On an unknown date, Blood sodium (136.00-147.00 10 thousand per litre): 138.00 10 thousand per litre 138.00. On an unknown date, Blood urea (8.00-25.00 mg/dl): 12.20 mg/dl 12.20. On an unknown date, Blood urea nitrogen/creatinine ratio (7.00-40.00): 12.32 12.32. On an unknown date, C-reactive protein: positive positive and positive. On an unknown date, Carbon dioxide (22.00-32.00 10 thousand per litre): 24.40 10 thousand per litre. On an unknown date, Eosinophil count (0.03-0.62 %): 0.03 % 0.03 and 0.3 % 0.3. On an unknown date, Globulin (2.10-4.60): 2.34 2.34. On an unknown date, Glomerular filtration rate: >60 >60 and >60. On an unknown date, Glucose tolerance impaired (100-125 mg/dl): >=126mg/dl mg/dl >=126mg/dl. On an unknown date, Haematocrit (39.4-49.3 %): 46.4 % 46.4. On an unknown date, Haemoglobin (13.4-16.9 g/dL): 16.3 g/dL 16.3. On an unknown date, Influenza: negative negative and negative negative. On an unknown date, Lymphocyte count (0.68-3.16 %): 1.06 % 1.06 and 10.3 % 10.3. On an unknown date, Mean cell haemoglobin (27.55-32.83 pg/ml): 29.80 pg/ml 29.80. On an unknown date, Mean cell haemoglobin concentration (32.72-35.76 g/dL): 35.13 g/dL 35.13. On an unknown date, Mean cell volume (81.26-95.11 fL): 84.83 fL 84.83. On an unknown date, Monocyte count (0.35-1.19 %): 0.83 % 0.83 and 8.1 % 8.1. On an unknown date, Neutrophil count (1.51-6.67 %): 8.31 % 8.31 and 81.0 % 81.0. On an unknown date, Platelet count (145-321): 171 171. On an unknown date, Pneumonia mycoplasmal: non-reactive non-reactive and non-reactive non-reactive. On an unknown date, Post laminectomy syndrome (70.00-99.00 mg/dl): 114.80 mg/dl 114.80. On an unknown date, Protein total (6.30-8.30 g/dL): 7.44 g/dL 7.44. On an unknown date, Red blood cell count (4.39-5.69): 5.47 5.47. On an unknown date, Red cell distribution width increased (11.6-14.7 %): 12.2 % 12.2. On an unknown date, White blood cell count (4.36-10.46): 10.26 10.26.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Most recent FOLLOW-UP information incorporated above includes: On 13-Apr-2021: No specific follow-up information recorded.