had fatigue; headache; anxiety issues; ever since taking the COVID vaccine, his wife is foggy; This is a spontaneous report received from contactable reporter(s) (Consumer or other non-HCP) from medical information team.  A 54-year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 26Apr2021 (Lot number: EW0171) at the age of 54 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "thyroid" (ongoing), notes: Concomitant Products: Caller explains his wife takes thyroid medication, clarified as Synthroid, but she has been on this medicine for 5-6 years, maybe longer. She didn't have any problems with it. She was still going to gym, running her daily life while being on this medication. Concomitant medication(s) included: SYNTHROID taken for thyroid disorder (ongoing). Vaccination history included: Bnt162b2 (Vaccine Name: First dose of Pfizer COVID vaccine, Lot Number / Expiry Date: EW0151/ unknown, Caller makes the comment while providing Lot number that he believes the third digit is a zero, confirming the Lot number as EW0151.   , Route, Anatomical Location:  Left arm, No. of Previous Doses: This was dose 1), administration date: 05Apr2021, when the patient was 53 years old, for COVID-19 Immunization, reaction(s): "fatigue", "headache", "anxiety issues", "she was feeling uneasiness.". The following information was reported: FATIGUE (non-serious) with onset 2021, outcome "not recovered", described as "had fatigue"; HEADACHE (non-serious) with onset 2021, outcome "unknown", described as "headache"; ANXIETY (non-serious) with onset 2021, outcome "unknown", described as "anxiety issues"; FEELING ABNORMAL (non-serious) with onset 2021, outcome "unknown", described as "ever since taking the COVID vaccine, his wife is foggy".  Additional information: Caller stated, His wife received 3 doses of the vaccine: 1st 05Apr2021, 2nd 26Apr2021 and 3rd 26Aug2021. "After the first and second dose, she had fatigue, headache, anxiety issues. Caller explains after his wife took the first shot, a couple of weeks later, she was feeling uneasiness. She had fatigue, headache, anxiety, and all of that. However, they did not really did not pay attention to it, they thought it just may be something and did not attach it to being from the vaccine. As time went on, she took the second shot and she was still feeling fatigue after that. A lot of people told her, she would feel fatigue for a couple of months and this and that as she was talking to people in the area. However, after she took the third shot, his wife really started having headaches and fainting spells. Caller clarifies his wife started fainting and after that her anxiety got much worse. She had severe headaches, tightness in her neck area. And then, she had sugar problems. Every time, she ate something, her sugar went through the roof. When she would eat some rice, her sugar would go up to 250-260 then within the next 20-30 minutes, her sugar would go down to 40 or 50. Caller states ever since she received the third dose she is having issue after issue with her sugar. She is not able to eat regular meals. Caller states his wife has been hospitalized 3 times. Caller mentions he was away so his 16 year old son had to take her to the ER 3 times. The caller clarifies she is still having tests run. She was told she had hypoglycemia. His wife never had any sugar issues and never took any medicine for sugar or had any other problems with her sugar prior to the vaccines. His wife was pretty healthy and was going to gym all the time prior to the COVID vaccine. Ever since these vaccines, she has started to have fatigue and has lost 12-13lbs over the last few months because she has not been able to eat. The caller explains they have taken her to so many doctors including an Endocrinologist and GI doctors. She is still having tests run. They took his wife to withheld, withheld where their daughter is a doctor their and she was taking to withheld which is a hospital there. His wife has also been to the hospital in withheld. She has another test next week clarified as an ultrasound of her stomach. All of the test are coming back with her being hypoglycemic. She is not able to eat normal meals. The only thing she is having to eat in the morning is oatmeal and even at night, she will eat oatmeal. She cannot take any juices or have any normal meals. She cannot even eat rice. The caller explains he was calling today because he is trying to get help on what can they do. The main problem she is having is the sugar issue. Any time, she eats something, her sugar goes up so high and then goes down. She is not able to eat anything. This has never happened to her before. His wife has never had diabetes and nobody in her family has any issues with that. Now, they are not able to go out to eat or do anything. Anytime she eats, her sugar goes up. First time his wife went to the ER was 05Oct2021 or 06Oct2021. She was discharged at the ER after about 6 hours. The second time, she had the same symptoms. She had the fainting spell, sugar issues and she spent 2 days in the hospital. He clarifies the second visit was 08Oct2021 to 09Oct2021. She was admitted into the hospital and was there for 2 days. Caller clarifies his wife did not go to the hospital for a third time. She just went to her doctors after the second visit. He again states his wife has seen an Endocrinologist and GI doctors. His wife is still having test run and nobody can find out why she is hypoglycemic. Caller also adds ever since taking the COVID vaccine, his wife is foggy. She will be asked questions, and it is like his wife is not there. She has a hard time remembering things. The caller does not know why. This never happened before. Concomitant Products: Caller explains his wife takes thyroid medication, clarified as Synthroid, but she has been on this medicine for 5-6 years, maybe longer. She did not have any problems with it. She was still going to gym, running her daily life while being on this medication. Now after getting the vaccines, they do not go anywhere. She cannot eat out because she has sugar issues with anything she eats. She cannot have a piece of bread, cereal or her blood sugar shoots up.   No follow-up attempts are possible. No further information is expected.