immune system is down /it's lowered my immune system; I've always had kind of a bad reaction/Moderna vaccine is actually damaging me/getting things which patient never had in life; I've been Kind of laid low for several days; Got Genital-herpes/outbreak of Genital-herpes again; Moderna vaccination apparently didn't protect me; Got Covid; I was really quite ill; This spontaneous case was reported by a patient and describes the occurrence of IMMUNOSUPPRESSION (immune system is down /it's lowered my immune system) in a 79-year-old patient of an unknown gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (unknown route) 1 dosage form. On an unknown date, the patient experienced IMMUNOSUPPRESSION (immune system is down /it's lowered my immune system) (seriousness criterion medically significant), IMMUNISATION REACTION (I've always had kind of a bad reaction/Moderna vaccine is actually damaging me/getting things which patient never had in life), MALAISE (I've been Kind of laid low for several days), DRUG INEFFECTIVE (Moderna vaccination apparently didn't protect me), COVID-19 (Got Covid) and ILLNESS (I was really quite ill). an unknown date, the patient experienced GENITAL HERPES (Got Genital-herpes/outbreak of Genital-herpes again). At the time of the report, IMMUNOSUPPRESSION (immune system is down /it's lowered my immune system), IMMUNISATION REACTION (I've always had kind of a bad reaction/Moderna vaccine is actually damaging me/getting things which patient never had in life), MALAISE (I've been Kind of laid low for several days), GENITAL HERPES (Got Genital-herpes/outbreak of Genital-herpes again), DRUG INEFFECTIVE (Moderna vaccination apparently didn't protect me), COVID-19 (Got Covid) and ILLNESS (I was really quite ill) outcome was unknown.        The action taken with SPIKEVAX NOS (SPIKEVAX NOS) (Unknown) was unknown.       No concomitant and treatment medications were reported. The patient had received Moderna shots since they came out. The patient always had kind of a bad reaction, been kind of laid low for several days. But the last time patient had it was particularly bad, and patient was really quite ill. And then a week later, got Genital-herpes, which the patient has never had in life. The patient's doctor said that the immune system was down. Then in July (unspecified year), the patient got Covid. The patient had been vaccinated all these times. Patient got covid. And then got an outbreak of Genital-herpes again. The patient can't believe this was good and stated that all the Moderna vaccination apparently didn't protect, and it's lowered immune system. The patient was now getting things which patient never had in life. So, the patient was really quite worried about it. The patient can't imagine patient would ever be an anti-vaxxer, but patient was beginning to think that way. Because the patient think the Moderna vaccine was actually damaging.  Company Comment: This is a Spontaneous case reported by a patient, concerning a 79-year-old patient of unknown gender, with no medical history reported, who experienced the unexpected and serious (due to medically significant) event of Immunosuppression, which occurred on an unknown date after an unspecified dose of SPIKEVAX NOS. As reported, patient experienced genital herpes and was told by her/his doctor that her/his immune system was down. No information disclosed about diagnostic tests performed, clinical course or treatments received. The benefit-risk relationship of SPIKEVAX NOS vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 13-Nov-2023: Significant live follow up received by safety on 14-Nov-2023 included: Complete information for reported adverse events event. References added.