nose ballooned 4 times its size; Her chin was filled with acne and rosacea; Her chin was filled with acne and rosacea; it has worsened; blistering things on her nose that were extremely painful; Draining pustules; Her right cheek was hot, and it was moving down to her chin and neck all around was so itchy; Head and neck rash and itching/Her head and scalp itching; head and neck rash and itching; nose still had red marks on it/She has red marks stuck on her nose and face. Saturday she got this big thing on the side of her cheek; nose hurt just to touch; Period after menopause; She was scratching her neck to where it was bleeding; bumps; very dry under her chin; This is a spontaneous report from a contactable consumer (patient). A 55-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: EW0165; Expiration Date: 31Aug2021), via an unspecified route of administration, administered in left arm on 08May2021 at 10:15 (at 55-year-old) as dose 2, 0.3 ml single for COVID-19 immunization. Medical history included ongoing Ulcerative colitis, ongoing Ulcerative proctitis, ongoing Crohn's, ongoing Rosacea, and patient had a compromised immune system (ongoing). She had Rosacea since she was in her 20s-30s. She got red cheek or flushed nose when she drank. She has been on metronidazole (METROGEL) for it for 30 years with no issue. No investigation assessment. There were no concomitant medications. The patient previously received the first dose of BNT162B2 (PFIZER BIONTECH COVID-19 VACCINE, solution for injection, 30mcg/0.3mL) via an unspecified route of administration, administered in Arm Left on 07Apr2021 10:30 (at the age of 55 years old) (Lot Number: ER8731; Expiration Date: 31Jul2021) as dose 1, 0.3 ml single for COVID-19 immunisation, and experienced some light bleeding after the first vaccination. No history of all previous immunization with the Pfizer vaccine considered as suspect. No additional vaccines administered on same date of the pfizer suspect. No other prior vaccinations within 4 weeks. The patient experienced period after menopause from 11May2021 and head and neck rash and itching from 12May2021. Head and neck rash and itching was reported as worsened. On 12May2021 she experienced her nose ballooning to 4 times its normal size with painful blisters on it that turned to draining pustules. Her right cheek was hot, and it was moving down to her chin and neck all around was so itchy. She had hot, red bumps and acne that turned to dry patches then to pustules and it moved from her face down. These symptoms continued and she had seen doctors from the Clinic including a Dermatologist. The Dermatologist reported that there were increased cases of Rosacea, Psoriasis, and Shingles in patients no matter what Manufacturer of the Covid-19 vaccine the patient received. She had been treated with Clindamycin that had helped her nose and the drainage there. She received a shot in the butt that was a steroid, but patient did not know what it was called. She had tried several creams and she read the side effects and wondered if they worsen her symptoms. The doctors all looked at her and threw things at her, but nothing was working. If there is a Booster dose, she will certainly not want that. Additional details: After the second shot, the patient's doctor told her to drink a ton of water and relax. She got the second shot on Saturday 08May2021. The next day and two days after she thought she got a placebo because nothing was happening. On the 3rd day after on 11May2021, she got a full blown period. She has not had a period in 7 years. She had a period in May2021 and Jun2021. She started a new pack of birth control Sunday. She just had a period last month. And she was still on the birth control pill. Her doctor was letting her finish out that medicine. She did have some light bleeding after the first shot too. She thought it was weird. But the periods in May2021 and Jun2021 were back to her old day periods. Last month it was only like 4 days long. It was not as bad. She thought this was great. She did contact the OB about her period. She said there have been reports of postmenopausal women getting their period. She was scheduled for Blood work and an ultrasound this month for that. On the 4th day, 12May2021, her nose ballooned 4 times its size. Her chin was filled with acne and rosacea. She had blistering things on her nose that were extremely painful. The right side of her cheek was really red and hot. Her husband stated it felt like it was on fire. It started on 12May2021, and it had worsened. It was like it was moving. Her nose had cleared up. She was first given Clindamycin, and that seemed to take down the puss filled stuff especially on her nose. They had like clear liquid in them. She thought maybe her acne and rosacea was triggered by the vaccine. Her nose still had red marks on it. Her nose hurt just to touch. On this past Saturday (May2021), 4 bumps came up on her chin. She was very dry under her chin too. She has bumps on the side under her ear. Her head and scalp itching. She has been doing laundry every day. She has not been using the same towels. Her face was not getting clear. Her neck started to itch. She had been hot from her neck up constantly. Her face was not clearing up. She has been to 3 different dermatologists. This last one gave her a shot of a steroid in her butt. She was scratching her neck to where it was bleeding. It was itching so bad. The doctor did not know. She has tried different lotions and gels they had prescribed with no results. She had red marks stuck on her nose and face. Saturday she got this big thing on the side of her cheek. Under her chin was very dry skin. Her neck had bumps all over. These were the products she tried for the facial bumps and itching: Eladel generic: Pimecrolimus cream 1%; NDC:# , Lot: 8128991, expiration: Jul2022. Adapalene Gel: 0.3%, NDC:# Lot:102039, expiration: Feb2023. Clindamycin: first thing, Phosphate topical lotion 1%, NDC:# DM4938, expiration: Mar2022. The doctor gave her a steroid shot in the butt. He said her itching should be improved, but it was not. She woke up this morning scratching her neck. This was the same doctor that prescribed her the first two medications. He told her to keep using the other two creams too. The events required a visit to physician office, did not require a visit to emergency room. No Relevant Tests, OBGYN Friday for blood work check hormones Ultrasound in 2 weeks. The outcome of the events her nose ballooning, head and neck rash and itching/Her head and scalp itching was not recovered, outcome of the other events was unknown.