Swollen ankles, feet, and calves; Swollen ankles, feet, and calves; Swollen ankles, feet, and calves; Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; more severe shortness of breath; Shortness of breath; Chest pressure; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 64 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 08Jan2022 10:30 (Lot number: FJ8762) at the age of 64 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Known allergies: Latex" (unspecified if ongoing), notes: Known allergies: Latex. Concomitant medication(s) included: VITAMIN D [COLECALCIFEROL]; CLONAZEPAM. Past drug history included: Ibuprofen, reaction(s): "Known allergies: Ibuprofen", notes: Known allergies: Ibuprofen; Paxil, reaction(s): "Known allergies: Paxil", notes: Known allergies: Paxil. Vaccination history included: Bnt162b2 (Prev dose Product: COVID 19, Prev dose Brand: Pfizer, Prev dose Lot number: ER8737, Prev dose Vaccine location: Right arm, Prev dose Dose number: 2), administration date: 21Apr2021, when the patient was 63 years old, for COVID-19 Immunization; Bnt162b2 (Prev dose Product: COVID 19, Prev dose Brand: Pfizer, Prev dose Lot number: ER8727, Prev dose Vaccine location: Left arm, Prev dose Dose number: 1), administration date: 24Mar2021, when the patient was 63 years old, for COVID-19 Immunization. The following information was reported: CHEST DISCOMFORT (medically significant) with onset 10Jan2022, outcome "recovering", described as "Chest pressure"; DYSPNOEA (medically significant) with onset 13Jan2022, outcome "recovering", described as "Shortness of breath"; JOINT SWELLING (medically significant), PERIPHERAL SWELLING (medically significant), PERIPHERAL SWELLING (medically significant) all with onset 22Jan2022, outcome "recovering" and all described as "Swollen ankles, feet, and calves"; TROPONIN T INCREASED (medically significant), CARDIAC DISORDER (medically significant), ASPARTATE AMINOTRANSFERASE INCREASED (medically significant), ALANINE AMINOTRANSFERASE INCREASED (medically significant), FIBRIN D DIMER INCREASED (non-serious) all with onset 22Jan2022, outcome "recovering" and all described as "Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated"; CONDITION AGGRAVATED (non-serious) with onset 20Jan2022, outcome "recovering", described as "more severe shortness of breath". The events "chest pressure", "shortness of breath", "swollen ankles, feet, and calves", "swollen ankles, feet, and calves", "swollen ankles, feet, and calves", "heart (troponin-t and d-dimer) and liver enzymes (alt and ast) were elevated", "heart (troponin-t and d-dimer) and liver enzymes (alt and ast) were elevated", "heart (troponin-t and d-dimer) and liver enzymes (alt and ast) were elevated", "heart (troponin-t and d-dimer) and liver enzymes (alt and ast) were elevated", "heart (troponin-t and d-dimer) and liver enzymes (alt and ast) were elevated" and "more severe shortness of breath" were evaluated at the physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: alanine aminotransferase: (22Jan2022) elevated, notes: Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; aspartate aminotransferase: (22Jan2022) elevated, notes: Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; blood test: (22Jan2022) unknown results; fibrin d dimer: (22Jan2022) elevated, notes: Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated; imaging procedure: (22Jan2022) no abnormalities; sars-cov-2 test: (22Jan2022) negative, notes: Covid test type post vaccination: Nasal swab; troponin t: (22Jan2022) elevated, notes: Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated. Therapeutic measures were not taken as a result of chest discomfort, dyspnoea, joint swelling, peripheral swelling, peripheral swelling, troponin t increased, cardiac disorder, aspartate aminotransferase increased, alanine aminotransferase increased, fibrin d dimer increased, condition aggravated. Clinical course included: Went to the ER and had blood tests and imaging done on 22Jan2022. Heart (troponin-T and d-dimer) and liver enzymes (ALT and AST) were elevated. Imaging at the time showed no abnormalities. Patient was not received any other vaccines within 4 weeks prior to the COVID vaccine. Prior to vaccination, Patient was not diagnosed with COVID-19. Since the vaccination, Patient was not tested for COVID-19.  No follow-up attempts are possible. No further information is expected.