burning; itching; rash; got much worse when she received her booster dose; booster dose; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 66 year-old female patient received bnt162b2 (BNT162B2), administration date Aug2021 (Batch/Lot number: unknown) at the age of 66 years as dose 3 (booster), single for covid-19 immunisation. The patient's relevant medical history was not reported. There were no concomitant medications. Vaccination history included: Bnt162b2 (first dose), administration date: Dec2020, when the patient was 65 years old, for COVID-19 immunization, reaction(s): "burning", "itching", "rash" two weeks after her first dose; Bnt162b2 (second dose), administration date: Jan2021, when the patient was 65 years old, for COVID-19 immunization. The following information was reported: IMMUNISATION (medically significant) with onset Aug2021, outcome "unknown", described as "booster dose"; BURNING SENSATION (medically significant), outcome "unknown", described as "burning"; PRURITUS (medically significant), outcome "unknown", described as "itching"; RASH (medically significant), outcome "unknown", described as "rash"; CONDITION AGGRAVATED (medically significant), outcome "unknown", described as "got much worse when she received her booster dose". The events "burning", "itching", "rash" and "got much worse when she received her booster dose" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: blood test: (2021) there was nothing wrong with her. Therapeutic measures were taken as a result of burning sensation, pruritus, rash, condition aggravated. Caller states that it got much worse when she received her booster dose. Right after she got the booster dose the rash exploded, meaning it got much worse. She had been experiencing this for 9 months with a rash that was primarily on her legs and arms. The rash began a couple weeks after her first dose, then it got better, then it would flare, then it would get better, and then it would flare again. She suffered with it for a month then finally went to her general practitioner who did bloodwork (had been extensive but there was nothing wrong with her), then to a dermatologist. She was taking medications such as Singulair, cetirizine and hydroxyzine. She said it was an awful burning and itching, constantly. She had been using a cream that was supposed to cost $7000, and it was not helping, called Episerum. Nothing helped her rash. She has also had been taking hydroxyzine HCl 25mg, one every 6-8 hours as needed for itching. She had been taking Cetirizine 10mg (expiry date 11Nov2022), once a day by mouth, since about a month ago, which was prescribed for the rash. She was cutting her vacation short to go home to go to the doctor where she had unspecified steroid shots twice, which helped a bit and then it didn't. Since getting the booster dose she had a steroid shot and was better for a week and a half then it was right back. She said she had used no new detergents or has not had any foods that would cause a reaction, which it was a reaction, her dermatologist thought it is from nothing the vaccine.  The lot number for bnt162b2 was not provided and will be requested during follow up.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101671029 same patient/different dose/AE