Developed asthma; Couldn't breathe; Was in distress; This spontaneous case was reported by a consumer and describes the occurrence of ASTHMA (Developed asthma), DYSPNOEA (Couldn't breathe) and RESPIRATORY DISTRESS (Was in distress) in a 65-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Upper respiratory infection. Concurrent medical conditions included Drug allergy (Patient was allergic to aspirin and lot of things. There was only two antibiotics patient was not allergic to which was not reported. ) and Asthma (Patient has a history of asthma attacks, but only when having upper respiratory infection.).   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced ASTHMA (Developed asthma) (seriousness criterion medically significant), DYSPNOEA (Couldn't breathe) (seriousness criterion medically significant) and RESPIRATORY DISTRESS (Was in distress) (seriousness criterion medically significant). The patient was treated with PREDNISONE for Adverse event, at an unspecified dose and frequency. At the time of the report, ASTHMA (Developed asthma), DYSPNOEA (Couldn't breathe) and RESPIRATORY DISTRESS (Was in distress) outcome was unknown.            Concomitant product use was not provided by the reporter.  Patient got Moderna vaccine in spring, both doses.   Visited five times in the Emergency Room, twice at the Emergency Care and five times on Prednisone. Patient was in two different antibiotics, but asthma persisted. Doctor changed prescription for regular inhaler to Prednisone. Patient's lung doctor specialist said asthma was not related to the vaccine.  Company Comment: This case concerns a 65-year-old male patient with relevant medical history Drug Allergy and Asthma, who experienced the serious unexpected events of Asthma, Dyspnea, and Respiratory Distress. The events, which were medically significant occurred on an unknown date after receiving the second dose of mRNA-1273 Vaccine. The patient had several visits to the Emergency Department due to his symptoms and was given Prednisone as treatment. The rechallenge was not applicable since no dose number was given. The medical history of Drug Allergy and Asthma remains a confounder. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Sender's Comments: This case concerns a 65-year-old male patient with relevant medical history Drug Allergy and Asthma, who experienced the serious unexpected events of Asthma, Dyspnea, and Respiratory Distress. The events, which were medically significant occurred on an unknown date after receiving the second dose of mRNA-1273 Vaccine. The patient had several visits to the Emergency Department due to his symptoms and was given Prednisone as treatment. The rechallenge was not applicable since no dose number was given. The medical history of Drug Allergy and Asthma remains a confounder. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.