horrible taste in my mouth /comes back full force; COVID-19; This spontaneous case was reported by a patient and describes the occurrence of TASTE DISORDER (horrible taste in my mouth /comes back full force) and COVID-19 (COVID-19) in a 49-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.    Co-suspect product included non-company product NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment.    Previously administered products included for Product used for unknown indication: PFIZER BIONTECH COVID-19 VACCINE (Dose Number: 2 batch/lot No: 026B21A; location of injection: left arm) on 10-Apr-2021. Past adverse reactions to the above products included No adverse event with PFIZER BIONTECH COVID-19 VACCINE. Concurrent medical conditions included Asthma and Fruit allergy. Concomitant products included FLUTICASONE PROPIONATE, SALMETEROL XINAFOATE (ADVAIR) and TRAZODONE HYDROCHLORIDE from 01-Nov-2021 to an unknown date for an unknown indication.   On 31-May-2022, the patient started NIRMATRELVIR, RITONAVIR (PAXLOVID) (unknown route) at an unspecified dose. On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In May 2022, the patient experienced COVID-19 (COVID-19). On 31-May-2022 at 8:00 PM, the patient experienced TASTE DISORDER (horrible taste in my mouth /comes back full force). At the time of the report, TASTE DISORDER (horrible taste in my mouth /comes back full force) had not resolved and COVID-19 (COVID-19) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   It was reported that, the patient developed a horrible taste in her mouth after taking the Paxlovid. It started to lessen just before when she was due to take the next dose. Shortly after taking the next dose, it comes back with full force. Nothing seemed to lessen it or make it go away. At the time of this report, the patient was on day 2 of the 5 days and mentioned that it was going to be hard to make it through all 5 days and it was that bad.  The patient did not receive any treatment for event horrible taste.  Company comment  This spontaneous case reported by a patient, concerns a 49-year-old female patient with no relevant medical history reported, who experienced the unexpected, non serious AESI of covid 19, unknown days after receiving a dose of mRNA-1273 vaccine in the covid 19 vaccination series. Patient received a previous dose with Pfizer Vaccine in April 2021, with no adverse events reported for Pfizer vaccine. Interchange of vaccine products was noted. The patient also experienced the non serious event of Taste disorder. Concomitant products included fluticasone propionate, salmeterol xinafoate (advair) and trazodone hydrochloride for an unknown indication. On an unknown date In May 2022, the patient experienced COVID-19. On 31-May-2022, the patient started treatment with nirmatrelvir, ritonavir (PAXLOVID). It was reported that, the patient developed a horrible taste in her mouth after taking the Paxlovid. The patient did not receive any treatment for event horrible taste. Outcome of covid 19 was unknown.  Ongoing Covid 19 pandemia is a  confounder. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed per Medical judgement.; Sender's Comments: This spontaneous case reported by a patient, concerns a 49-year-old female patient with no relevant medical history reported, who experienced the unexpected, non serious AESI of covid 19, unknown days after receiving a dose of mRNA-1273 vaccine in the covid 19 vaccination series. Patient received a previous dose with Pfizer Vaccine in April 2021, with no adverse events reported for Pfizer vaccine. Interchange of vaccine products was noted. The patient also experienced the non serious event of Taste disorder. Concomitant products included fluticasone propionate, salmeterol xinafoate (advair) and trazodone hydrochloride for an unknown indication. On an unknown date In May 2022, the patient experienced COVID-19. On 31-May-2022, the patient started treatment with nirmatrelvir, ritonavir (PAXLOVID). It was reported that, the patient developed a horrible taste in her mouth after taking the Paxlovid. The patient did not receive any treatment for event horrible taste. Outcome of covid 19 was unknown.  Ongoing Covid 19 pandemia is a  confounder. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed per Medical judgement.