Within 5 min of shot a weird sensation from injection site up to her head and across chest; Face became flushed; Heartbeat rapid; Pressure in back of neck and head; Pressure in back of neck and head/ Pressure moved to right shoulder; head and right wrist started to itch/ felt itchy all over; one red hive on her right wrist that became "more itchy to the touch or if scratched"; Very tip of tongue tingled; Inside left nostril one spot extremely itchy as if had a hive; Mild chills; Mild aches; This is a spontaneous report from a contactable other health care professional (patient). A 60-year-old non-pregnant female patient received first dose of bnt162b2 (PFIZER BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot Number: EWO150) via an unspecified route of administration in the left arm on 16Apr2021 at 09:00 (at the age of 60-year-old) as dose 1, single for covid-19 immunization. Patient was not pregnant at time of vaccination. The patients' medical history included known allergies to food, allergies to medications and environmental allergy from an unknown date and unknown if ongoing. Prior to the vaccination, the patient was not diagnosed with covid-19. Concomitant medication(s) included colecalciferol (VIT D3), olopatadine (OLOPATADINE), montelukast (MONTELUKAST), levothyroxine sodium (SYNTHROID), fexofenadine hydrochloride (ALLEGRA) and "P" (unspecified), all taken for an unspecified indication, start and stop date were not reported; and unknown if ongoing. The patient did not receive any other vaccines within four weeks prior to the COVID-19 vaccination. On 16Apr2021 at 09:00, within 5 minutes of the shot, the patient experienced a weird sensation from injection site up to her head and across chest, her face became flushed, her heartbeat rapid, the registered nurse (RN) at the vaccination site a put blood pressure (BP) cuff on until her BP came down. On 16Apr2021 at 10:00, approximately 1 hour later the pressure in back of neck and head moved to the right shoulder, in all lasted approximately 20 minutes. The patient thought of going back to the hospital. Later that evening her head and right wrist started to itch. The patient observed one red hive on her right wrist that became "more itchy to the touch or if scratched". The patient took a small dose of diphenhydramine acetaminophen (BENADRYL) 5 ml (milliliters) and fell asleep. On 16Apr2021 at 21:30, the patient woke up and felt itchy all over. On 16Apr2021, the patient reported that the very tip of her tongue tingled and inside her left nostril one spot was extremely itchy as if she had a hive. The patient also experienced mild chills and mild aches and went to bed without taking more acetaminophen (TYLENOL) or diphenhydramine acetaminophen (BENADRYL). It was unknown whether any therapeutic measures were taken for the events within 5 min of shot a weird sensation from injection site up to her head and across chest, face became flushed, heartbeat rapid, pressure in back of neck and head, pressure moved to right shoulder, very tip of tongue tingled, inside left nostril one spot extremely itchy as if had a hive, mild chills and mild aches. Outcome of the events pressure in back of neck and head; and pressure moved to right shoulder was recovered on 16Apr2021 and outcome for rest of other events was recovering.  No follow-up attempts are needed. No further information is expected.