Lips swollen and look thick; Lip itches; Like a mosquito bump on side of her lip; Felt hives in the lips/she had hives on her back; This is a spontaneous report from a contactable consumer or other non hcp.   A 27-year-old female patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: EW0187), via an unspecified route of administration, administered in Arm Left on 27Jul2021 (at the age of 27-years-old) as DOSE 1, SINGLE for covid-19 immunisation.  Medical history included asthma (Has asthma, kind of like induced asthma. Does not have to take Albuterol often), seasonal allergy, Acid reflux from an unknown date and unknown if ongoing. There were no concomitant medications. No Family Medical History (all of her family mostly got the Pfizer or the Moderna and they were fine). Time the Vaccination was as Given Was around 1:30 pm or 2:00pm in the afternoon. Time of Onset was (24-hour clock) was last night, early this morning around 2:00, 3:00 or 4:00 am. No emergency room visit, No visit to physician office. Prior vaccination was none. Adverse event following prior vaccinations was None. Relevant Tests was None. Caller states she is calling regarding the Pfizer Covid vaccine and that she had a reaction to it. She got it yesterday, and she usually has delayed reactions. The patient experienced lips swollen and look thick, lip itches on 27Jul2021 and like a mosquito bump on side of her lip, felt hives in the lips/she had hives on her back on Jul2021.She woke up and her lips were swollen. It was all of her lips, and her upper lip and if she touches it, it itches. Lips swollen: She felt it at night but was just sleeping, she did not think about it until she woke up this morning. Her lips are thin and this does not look normal. They look real thick. It feels itchy in her upper lip. Started last night. This was a delayed reaction. She went to bed probably around 12:00am, so it was probably around 2:00, 3:00, or 4:00 in the morning and it has gotten worse. Before, she would usually take allergy medication. She was going to ask if she should do that or if she should go ahead and take another stronger one, like Benadryl. Before she drinks medication, she wants to know which one she should drink for better results. Indication: Was a long time to think if she was going to get it or not. She was getting it because of the Delta one and to feel a little bit better. Has asthma, kind of like induced asthma. Does not have to take Albuterol often. Prior to that, she just has to have allergy shots. She had it last on Friday, was like 3 or 4 days before. Does not know that name of the medication. They do not tell her. She goes to get the shot every week. When she got married into the military, she was getting it for like a year before marrying him but then they stopped treating it because of Covid. She had never got swollen before until they stopped it. Because of Covid, they stated they could not treat with the shot. The allergist said when they started that she did not have a reaction. Since then, she had hives on her back. Her lips had gotten swollen before but not the same as this. When giving the vaccine, on the side of her lip, was like a mosquito bump but getting bigger, only on one side and is itchy. That did not happen last Friday. She got a delayed reaction and did not get it at the time of the vaccine. This past Friday, she had not gotten anything previous. Then, she just takes Claritin and it helps. She had not gotten the allergy shot for a year and a half.  Has been taking it again for like a month or 2 months and 2 weeks. They just changed the serum. They have to reduce the serum and even when they reduced the serum to dilute it, she felt the hives in the lips. This is new and has not happened before getting the  allergy shots. They thought maybe, living in a new city had caused it but living a whole year and a half and had not been swollen, it should not be the state of Withheld. States that the allergies are the whole seasonal year allergies. Therapeutic measures were taken with Claritin as a result of like a mosquito bump on side of her lip and for rest event therapeutic measure were taken as no. The patient underwent lab tests and procedures which included investigation auto immune: normal on an unspecified date. The outcome of event Lips swollen and look thick, Lip itches and was like a mosquito bump on side of her lip was Not recovered and outcome of event felt hives in the lips/she had hives on her back was unknown.  Description of Product Complaint: Description of complaint: Caller is reporting swollen and itchy lips after receiving the first dose of the Pfizer Covid 19 vaccine. Caller mentioned that she has been taking allergy shots but the name is unknown. States that she goes once a week to get them. She was taking them about a year before it was stopped due to Covid. She had just started taking it again about a month and 2 weeks ago. She had never got swollen before until they stopped it. Since then, she had hives on her back. Her lips had gotten swollen before but not the same as this. They just changed the serum. They have to reduce the serum and even when they reduced the serum to dilute it, she felt the hives in the lips. This is new and has not happened before getting the allergy shots.   Follow-up attempts are completed. No further information is expected.