sweating but wasn't running a fever; really tired; in bed for 8 days and couldn't get out of bed/was in bed for a week; having a hard time breathing; in bed for 8 days and couldn't get out of bed; couldn't hardly eat, and had no appetite; really bad headache, a prickly headache; no appetite; This is a spontaneous report from a contactable consumer or other non hcp. A 70-year-old male patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for Injection, Batch/Lot number was not reported), via an unspecified route of administration on 23Feb2021 at 11:00 (at the age of 70-year-old) as dose 1, single for COVID-19 immunization. The patient medical history included ongoing COPD (diagnosed at least 10 years ago), ongoing high blood pressure (diagnosed maybe 15 years ago). The patient concomitant medications included felodipine at a dose of 5 mg once a day taken for high blood pressure; procaterol hydrochloride (PRO-AIR) at a dose of 90 ug (rescue inhaler as needed; been on for at least 5 years) taken for COPD; tiotropium bromide monohydrate (SPIRIVA) at a dose of 2.5 ug two times a day (been on for at least 5 years) taken for COPD; albuterol (SALBUTAMOL) at a dose of 0.083%, four times a day (0.083% use 1 vial, up to 4 times a day as needed; Nebulizer; stated usually does once a day but right now he does it more because he can't breathe) taken for COPD; breo (been on for at least 5 years) taken for unspecified indication, all drugs start and stop date were not reported. The patient did not receive any other vaccine prior vaccinations within 4 weeks. On 23Feb2021, the patient experienced having a hard time breathing, in bed for 8 days and couldn't get out of bed, couldn't hardly eat, and had no appetite, really bad headache, a prickly headache, no appetite, really tired, in bed for 8 days and couldn't get out of bed/was in bed for a week. On 24Feb2021, the patient experienced sweating but wasn't running a fever. Reporter stated she is calling about the Vaccine; confirmed Pfizer Covid Vaccine. Stated her husband has gotten 2 shots of the vaccine and he has respiratory issues and he is having pretty bad side effects, asks what type of research was done on people with respiratory issues that received the vaccine. Adverse Events following First Dose: Patient had his first dose on 23Feb2021 and then later that day he had a really bad headache, a prickly headache. Stated on 24FEB2021 he was sweating but wasn't running a fever and that ended 24FEB2021, states then he was in bed for 8 days and couldn't get out of bed, couldn't hardly eat, and had no appetite. Stated she said she needs to take him to the hospital. Stated he was also having a hard time breathing, he does have COPD. Stated knowing how men are, he didn't want to go. Stated she called the health line on their insurance care and the nurse there said yes, he should go, so the patient said maybe in the morning he would go. The next morning, he felt a little better but he was still really tired and had the headache for 8 days and then it subsided. Stated she asked him if he was going to feel okay for the second dose. Stated for about two weeks he was feeling better and now he is not feeling good again. Event Information: Event experienced: was in bed for a week Date started: 23Feb2021; Date stopped: 3Mar2021. Admission to the hospital due to event: unknown. Any treatment received: unknown. Still experiencing: recovered. Reporter is asking if there is any specific data, research done by Pfizer on people with respiratory disease and does this population have more severe side effects. My husband has COPD. He received the 2nd Pfizer dose on 16Mar21 and his breathing is worse and has been in bed x16 days. The reporter stated he was in bed for a week with the 1st vaccine dose. Outcome of the events no appetite was not recovered; sweating but wasn't running a fever was recovered on 24Feb2021; outcome of remaining events was recovered on 03Mar2021.  Information on the lot/batch number has been requested.  Follow-up (PRD/SRD 11May2021): Follow-up attempts completed. No further information expected.