Shortness of breath; Rapid heart beat; Pain at the injection site; Redness at site of Injection; Swollen site of injection; This spontaneous case was reported by a physician (subsequently medically confirmed) and describes the occurrence of INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection), INJECTION SITE SWELLING (Swollen site of injection), DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat) in a 22-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No medical history information was reported.     On 12-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 13-Jan-2021, the patient experienced INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection) and INJECTION SITE SWELLING (Swollen site of injection). On 19-Jan-2021, the patient experienced DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat). At the time of the report, INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection), INJECTION SITE SWELLING (Swollen site of injection), DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment details includes- Benadryl 50mg IM, Solu Medrol IM, Prednisone, Zyrtec, Ibuprofen, Ice.   No concomitant medication was reported. This case was received via an unknown source (no reference has been entered for a health authority or license partner) on 23-Jan-2021 and was forwarded to Moderna on 23-Jan-2021.    This spontaneous case was reported by a physician (subsequently medically confirmed) and describes the occurrence of INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection), INJECTION SITE SWELLING (Swollen site of injection), DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat) in a 22-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No medical history information was reported.     On 12-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 13-Jan-2021, the patient experienced INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection) and INJECTION SITE SWELLING (Swollen site of injection). On 19-Jan-2021, the patient experienced DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat). At the time of the report, INJECTION SITE PAIN (Pain at the injection site), INJECTION SITE ERYTHEMA (Redness at site of Injection), INJECTION SITE SWELLING (Swollen site of injection), DYSPNOEA (Shortness of breath) and HEART RATE INCREASED (Rapid heart beat) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment details includes- Benadryl 50mg IM, Solu Medrol IM, Prednisone, Zyrtec, Ibuprofen, Ice.   No concomitant medication was reported.