he received 2 doses of the Moderna COVID19 vaccine and experienced 5 strokes.; he had five mayor lesions on the left side of his brain; trauma; Patient received the 2nd dose on May 6th 2021 and two weeks before that received the 1st dose on April; This spontaneous case was reported by a patient and describes the occurrence of CEREBROVASCULAR ACCIDENT (he received 2 doses of the Moderna COVID19 vaccine and experienced 5 strokes.), CENTRAL NERVOUS SYSTEM LESION (he had five mayor lesions on the left side of his brain) and INJURY (trauma) in a 56-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   In April 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 06-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 06-May-2021, the patient experienced INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient received the 2nd dose on May 6th 2021 and two weeks before that received the 1st dose on April). On an unknown date, the patient experienced CEREBROVASCULAR ACCIDENT (he received 2 doses of the Moderna COVID19 vaccine and experienced 5 strokes.) (seriousness criteria hospitalization and medically significant), CENTRAL NERVOUS SYSTEM LESION (he had five mayor lesions on the left side of his brain) (seriousness criterion hospitalization) and INJURY (trauma) (seriousness criterion hospitalization). The patient was hospitalized on 14-Jun-2022 due to CENTRAL NERVOUS SYSTEM LESION, CEREBROVASCULAR ACCIDENT and INJURY. At the time of the report, CEREBROVASCULAR ACCIDENT (he received 2 doses of the Moderna COVID19 vaccine and experienced 5 strokes.), CENTRAL NERVOUS SYSTEM LESION (he had five mayor lesions on the left side of his brain), INJURY (trauma) and INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient received the 2nd dose on May 6th 2021 and two weeks before that received the 1st dose on April) outcome was unknown.            No concomitant medications were reported. It was reported that the patient was hospitalized with Code Red. Patient did not know what happened as he did not remember. Patient passed out. No treatment details were reported.  Company comment: This spontaneous case concerns a 56 year old male with no reported medical history who experienced the unexpected serious (hospitalization, medically significant) adverse event of special interest cerebrovascular accident and the unexpected serious ( hospitalization) event of central nervous system lesion and injury. The events occurred at an unknown interval after receiving the second dose of mRNA1273. It should be noted that the patient received the second dose of mRNA1273 two weeks after the first dose which is not in alignment with the recommended dosing interval (inappropriate schedule of vaccine administered). The patient was reported to have had 5 strokes post vaccination including 5 major lesions on the left side of his brain. The patient also experienced trauma, he passed out and was not able to remember the events that happened.  Further details regarding the clinical course, additional diagnostic or imaging test done and treatment were not provided.  The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 56 year old male with no reported medical history who experienced the unexpected serious (hospitalization, medically significant) adverse event of special interest cerebrovascular accident and the unexpected serious ( hospitalization) event of central nervous system lesion and injury. The events occurred at an unknown interval after receiving the second dose of mRNA1273. It should be noted that the patient received the second dose of mRNA1273 two weeks after the first dose which is not in alignment with the recommended dosing interval (inappropriate schedule of vaccine administered). The patient was reported to have had 5 strokes post vaccination including 5 major lesions on the left side of his brain. The patient also experienced trauma, he passed out and was not able to remember the events that happened.  Further details regarding the clinical course, additional diagnostic or imaging test done and treatment were not provided.  The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.