This case was reported by a consumer via call center representative and described the occurrence of local swelling in a 59-year-old female patient who received Influenza vaccine Quadrivalent. The patient's past medical history included stent placement (in 1999), splenectomy (on 6th December 2006), accident (in 2007), pancreatectomy, hysterectomy, endometriosis and pneumonia (4 times in past 10 years). Previously administered products included PPSV-23 (in December 2011), MACRODANTIN and DILAUDID. Concurrent medical conditions included traumatic brain injury, unwell (from 6 months), numbness of lower extremities (numbness below waist), double ureter (on left kidney), drug intolerance (morphine intolerance), bronchitis and tinnitus. Concomitant products included PCV 13 vaccine. In September 2016, the patient received Influenza vaccine Quadrivalent. On an unknown date, less than a month after receiving Influenza vaccine Quadrivalent, the patient experienced local swelling, sebaceous cyst, tinnitus aggravated, wheezing, allergic reaction and pruritus. The patient was treated with BENADRYL and clobetasol propionate. On an unknown date, the outcome of the local swelling, sebaceous cyst, tinnitus aggravated, wheezing, allergic reaction and pruritus were unknown. It was unknown if the reporter considered the local swelling, sebaceous cyst, tinnitus aggravated, wheezing, allergic reaction and pruritus to be related to Influenza vaccine Quadrivalent. Additional details were provided as follows: On 6th December 2006, the patient's surgery was done 10 years ago. The patient was told by the surgeon who did patient's splenectomy and 1/2 her pancreas that she would need to have the booster every 4 or 5 years. The patient literally had to fight to get the shots because no on seems totally comfortable deciding that it should be taken. In May 2007, the patient had traumatic brain injury and she has some numbness below the waist. She had an auto accident in which should have killed the patient. In December 2011, the patient had PPSV23. The patient had endometriosis and complete hysterectomy. The patient had a double ureter on left kidney no one knows if it drains, but it is how they found out she couldn't tolerate morphine when they had her in the hospital for the splenectomy. It was comparable pain to the 2 stent placements she had in 1999. The pain was unbearable. The patient had pneumonia at least 4 different times 10 years ago. Bronchitis which she had and the doctors were always concerned about. The patient had been on extended antibiotic regime for some parts of the patient's life pre-divorce because her husband would contaminate her and it was usually MACRODANTIN. During the last 6 months the patients have been ill. The patient had a roommate who worked with a woman who recently died suddenly. The girl lived her 2 months. The patient asked her to ask at work what killed the woman because she might have something from her work. The patient knew her friend from past 4 months. She had to console her. The patient stopped hugging her when the Chiggers happened. The patient received a Flu shot from a new doctor she saw in September downplayed everything she told her. The patient went back a month later and received PCV-13 intramuscularly. The patient notified doctor about the cyst. No one has contacted the patient about a weight gain diet. There was no follow up until March 2017. The patient was seeking a different doctor and waited 5 months for doctor. The patient was wondering if the flu shot didn't manifest itself when she took it. She had a painful lump suddenly appeared on her back, a doctor in an emergency room said it was a sebaceous cyst. The patient had excruciating pain all summer and it caused pain to lift and walk. The sore took about 6 weeks to go away with regular application of ointments and cream. No one had ever cut it. The patient was comfortable when scab was removed. The patient lost 56+/- lbs without trying since she went off all medication in April. She was on 7. She felt much better overall. The patient had tinnitus which seems to have become worse recently. In October, the patient had accidentally gotten into chiggers and ticks without realizing it, and became horrible affected with the bites and sites where the ticks got into skin for 5 days. The patient thought it was an allergic reaction in her blood stream, but no one has drawn blood. The patient had respiratory wheezing. The patient was very active outdoor winter sport skiing cross county. She went from being very active to a very sedint.