they tingle; huge welt,  5 red welts, welts on her stomach; burning; Itchy; red patch,  blistered, blister on her Right knee, set of blisters on her Left hip; a red patch on her back; painful, was an uptick in pain; scabbed; severe stomach pain and burning/acid indigestion; severe stomach pain, pain like if someone had tore her stomach open; pain at the injections site; This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 68-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included famotidine unknown for stomach pain and acid indigestion and calcium carbonate (Tums) for stomach burning sensation of.   The patient's past medical history included lyme disease. Previously administered products included COVID vaccine. Concurrent medical conditions included rheumatoid arthritis, hashimoto's disease, autoimmune disorder and food allergy.   On 26th October 2021, the patient received the 2nd dose of Shingrix. On 27th October 2021, the patient started famotidine at an unknown dose and frequency and Tums at an unknown dose and frequency. On 26th October 2021, less than a day after receiving Shingrix and not applicable after starting famotidine, the patient experienced injection site pain. On 27th October 2021, the patient experienced stomach burning sensation of and stomach pain. In March 2022, the patient experienced pruritus, blister, erythema, pain and scab. On 4th April 2022, the patient experienced welts and burning sensation skin. On 11th April 2022, the patient experienced tingling. The action taken with Tums was unknown. On an unknown date, the outcome of the injection site pain, tingling, welts, stomach burning sensation of, stomach pain, pruritus, blister, erythema, pain, scab and burning sensation skin were unknown.   It was unknown if the reporter considered the injection site pain, tingling, welts, stomach burning sensation of, stomach pain, pruritus, blister, erythema, pain, scab and burning sensation skin to be related to Shingrix. It was unknown if the reporter considered the tingling, welts, pruritus, blister, erythema, pain, scab and burning sensation skin to be related to famotidine.     Additional Information: GSK receipt date: 11-APR-2022 Reporter's comment: The case reported by patient herself. The patient stated that she received her second dose of the SHINGRIX vaccine and experienced pain at the injections site. The next day, the patient experienced severe stomach pain and burning. She described the pain like if someone had tore her stomach open. The patient took Tums and Famotidine to help relieve symptoms.  The patient still continued to have acid indigestion, and needs to keep Tums and Famotidine near her for treatment. Between 1st March 2022 and 12th March 2022, she noticed a red patch on her back that was about 1/4 inch big that blistered and became itchy and painful. It had since scabbed over and was no longer painful.  On 4th April 2022 she developed another blister on her right knee, which started as a huge welt. She stated there was an uptick in pain in this location. She also experienced burning and itching. Current area was scabbed, and she did not feel pain, but she could feel something there. On 11th April 2022 she noticed another set of blisters, this time on her left hip. She described these as 5 red welts, that were not super painful, but they tingle. She was also noticing welts on her stomach as well. The reporter consented to follow up.  It was unknown if the reporter considered the tingling, welts, pruritus, blister, erythema, pain, scab and burning sensation skin to be related to Tums. Additional Supportive Information: The case has been linked with the case US2022063358 reported by same reporter.; Sender's Comments:  US-GLAXOSMITHKLINE-US2022063358:same reporter