Very sick; Doesnt know if it was coronavirus or reaction to vx; Aches, pains; Loss kneecaps to swelling; Inflamed joints; Red joints; This case was reported by a consumer and described the occurrence of sickness in a female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included folic acid unknown for drug use for unknown indication, colecalciferol (Vitamin D3) unknown for drug use for unknown indication, fluticasone propionate (Flonase) unknown for an unknown indication, levothyroxine sodium (Synthroid) for drug use for unknown indication, probiotics (nos) (Probiotic) for drug use for unknown indication, nabumetone for drug use for unknown indication, loratadine + pseudoephedrine sulfate (Claritin-D) for drug use for unknown indication, sarilumab (Kevzara) for drug use for unknown indication, vitamins nos (Multivitamin) for drug use for unknown indication and benadryl allergy (nos) (Benadryl Allergy) for drug use for unknown indication.   The patient's past medical history included arthritis (diagnosed Rheu arthritis). Previously administered products included Xeljanz. Concurrent medical conditions included sulfonamide allergy (had allergy for sulpfa antibiotic Benzoyl peroxide).   On an unknown date, the patient received Shingrix, folic acid at an unknown dose and frequency, Vitamin D3 at an unknown dose and frequency, Flonase at an unknown dose and frequency, Synthroid at an unknown dose and frequency, Probiotic at an unknown dose and frequency, nabumetone at an unknown dose and frequency, Claritin-D at an unknown dose and frequency, Kevzara at an unknown dose and frequency, Multivitamin at an unknown dose and frequency and Benadryl Allergy at an unknown dose and frequency. On an unknown date, unknown after receiving Shingrix, folic acid, Vitamin D3 and Flonase, the patient experienced sickness, coronavirus infection, pain, swelling of knees, joint inflammation and localized erythema. The action taken with folic acid was unknown. The action taken with Vitamin D3 was unknown. The action taken with Synthroid was unknown. The action taken with Probiotic was unknown. The action taken with nabumetone was unknown. The action taken with Claritin-D was unknown. The action taken with Kevzara was unknown. The action taken with Multivitamin was unknown. The action taken with Benadryl Allergy was unknown. On an unknown date, the outcome of the sickness and coronavirus infection were unknown and the outcome of the pain, swelling of knees, joint inflammation and localized erythema were recovering/resolving.   It was unknown if the reporter considered the sickness and coronavirus infection to be related to Shingrix, folic acid, Vitamin D3 and Flonase. It was unknown if the reporter considered the pain, swelling of knees, joint inflammation and localized erythema to be related to folic acid, Vitamin D3 and Flonase.  Additional details were provided as follows: The age at vaccination was not reported. The patient received Shingrix vaccine and was very sick and did not know if it was corona virus or reaction to vaccine. The patient was told to hold Xeljanz for 7 to 8 days when the patient got Shingrix vaccine. The patient missed some doses of Xeljanz and became sick.  Because of the missed doses, she had aches, pains, loss both knees caps to swelling, inflamed red joints, stating to get better. The patient was called and HIPPA was verified. Counseling points were completed. At the time of reporting, no updated to medications, diagnosis and allergies. The patient denied side effects. The patient was told to discuss with MD and counseled on missed doses and infection concern. The patient denied any questions or concerns at the time of reporting. It was unknown if the reporter considered the sickness and coronavirus infection to be related to Shingrix. It was unknown if the reporter considered the pain, swelling of knees, joint inflammation and localized erythema to be related to Synthroid, Benadryl Allergy, Probiotic, Nabumetone, Claritin-D, Kevzara and Multivitamin.