she was tired; feels drained; something walking on her lips feels like, her lips felt sandy; throat was swelling up; leg feels so tight she can not bend her knee; tendon and knee are really hurting; it really started to hurt me, the pain was really bad/ her right knee started to hurt; knee puffed up; the muscles hurt; This is a spontaneous report from a contactable consumer (patient). A 72-year-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, lot/batch number: EP6955) via an unspecified route of administration, administered in deltoid right on 19Mar2021 04:55 PM (age at the time of vaccination 72 years) as dose 2, single for covid-19 immunisation. The patient's medical history included high blood pressure, stent in her heart, asthma. Caller reported that she had knee surgery 4 and a half years ago (in 2016). She had food allergy, allergic to cranberry. The patient's concomitant medications included acetylsalicylic acid (ASPIRIN 81), vitamin D, vitamin C [ASCORBIC ACID], fish oil and blood pressure medication. The vitamin D was prescribed to her by her doctor two years ago. The vitamin D is a huge dose, she thought it was 50,000mg. She took it once a week, every Saturday. She received previously took first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, lot/batch number: EL3302), via an unspecified route of administration in right shoulder on 18Feb2021 on 5:00 PM as dose 1, single for covid-19 immunisation. She reported that after having her first vaccine dose she had some pain to her knee, muscle pain, body pain, tired but it went away. But after her second dose, which was 3 weeks ago this coming Friday, she reported that 1-2 days after her second dose, it was really started to hurt her, the pain was really bad, knee puffed up and the muscles hurt. After she received the second dose of the covid vaccine, as soon as she got it, within a few minutes after, her throat was swelling up and she felt like something was walking on her lips on 19Mar2021 . Clarified that it was hard to explain what something walking on her lips feels like, her lips felt sandy. She drank a lot of water and then she was okay. After she received her second dose of the covid vaccine, her right knee started to hurt. Three days ago, she started taking Tylenol. Between three days ago to the time of reporting, she took six Tylenol tablets. Tylenol was helping her. She stopped taking Tylenol and her knee started to hurt again. Her leg felt so tight that she could not bend her knee. Her tendon and knee were really hurting. Before she took Tylenol, she used roll on Lidocaine. She put that on and it only helped a little bit. Tylenol has helped her the most, it had the longest effect. She was tired, and in bed all day the day after receiving the vaccine on Saturday on 20Mar2021. Even on the time of reporting, she still got tired sometimes. She was not the person she used to be. She felt drained. Her tiredness has gotten better, but it was ongoing. Sometimes she still felt drained, it was coming and going. Her tiredness was nothing now compared. She was normally a very energetic person. The outcome of events throat was swelling up and her lips felt sandy was recovered on 19Mar2021 and outcome of events feels drained and tired was recovering, outcome of muscle pain was not recovered, and outcome of other events was unknown.  No follow-up attempts were possible. No further information was expected.