Left leg started cramping; left leg is having clotting; unable to get out of bed, was bedridden; just sick over and over get sick; infected in the nose and throat, constantly infected in the nose over and over again; constantly infected in the nose over and over again; injection site on arm painful; fatigue; thrombosis in legs, clotting in his legs, thighs and calves; hardening of the heart; His immunity is messed up; just a little achy; Long COVID, suffering a lot of long term COVID; lot of chest pain; Revaccination with Pfizer COVID-19 vaccine; Interchange of vaccine product; Immediately after got the Pfizer Covid Vaccine was feeling very unwell; This spontaneous case was reported by a patient and describes the occurrence of DEEP VEIN THROMBOSIS (thrombosis in legs, clotting in his legs, thighs and calves) in a 26-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 017C21A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product TOZINAMERAN (COMIRNATY) for an unknown indication.    The patient's past medical history included Addiction, Behavior disorder, Depression and Amphetamine abuse.   On 18-Oct-2021 at 11:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 18-Nov-2021, the patient received second dose of TOZINAMERAN (COMIRNATY) (unknown route) 1 dosage form. In November 2021, the patient experienced MALAISE (Immediately after got the Pfizer Covid Vaccine was feeling very unwell). On 18-Nov-2021, the patient experienced COVID-19 IMMUNISATION (Revaccination with Pfizer COVID-19 vaccine). 18-Nov-2021, the patient experienced INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine product). On 24-Jan-2022, the patient experienced CHEST PAIN (lot of chest pain). On an unknown date, the patient experienced DEEP VEIN THROMBOSIS (thrombosis in legs, clotting in his legs, thighs and calves) (seriousness criterion medically significant), CARDIAC DISCOMFORT (hardening of the heart), IMMUNE SYSTEM DISORDER (His immunity is messed up), PAIN (just a little achy), POST-ACUTE COVID-19 SYNDROME (Long COVID, suffering a lot of long term COVID), MUSCLE SPASMS (Left leg started cramping), COAGULOPATHY (left leg is having clotting), BEDRIDDEN (unable to get out of bed, was bedridden), ILLNESS (just sick over and over get sick), PHARYNGITIS (infected in the nose and throat, constantly infected in the nose over and over again), RHINITIS (constantly infected in the nose over and over again), VACCINATION SITE PAIN (injection site on arm painful) and FATIGUE (fatigue). At the time of the report, DEEP VEIN THROMBOSIS (thrombosis in legs, clotting in his legs, thighs and calves), CARDIAC DISCOMFORT (hardening of the heart), IMMUNE SYSTEM DISORDER (His immunity is messed up), CHEST PAIN (lot of chest pain), POST-ACUTE COVID-19 SYNDROME (Long COVID, suffering a lot of long term COVID), MALAISE (Immediately after got the Pfizer Covid Vaccine was feeling very unwell), MUSCLE SPASMS (Left leg started cramping), COAGULOPATHY (left leg is having clotting), BEDRIDDEN (unable to get out of bed, was bedridden), ILLNESS (just sick over and over get sick), PHARYNGITIS (infected in the nose and throat, constantly infected in the nose over and over again), RHINITIS (constantly infected in the nose over and over again) and FATIGUE (fatigue) had not resolved and PAIN (just a little achy), VACCINATION SITE PAIN (injection site on arm painful), COVID-19 IMMUNISATION (Revaccination with Pfizer COVID-19 vaccine) and INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine product) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, SARS-CoV-2 test: (Negative) get sick infected but testing negative for COVID.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Pfizer COVID-19 vaccine time was after 15:00-15:30. Immediately after he got the Pfizer Covid Vaccine he was feeling very unwell and figured well, it was supposed to be like this because it's stronger the second round. The patient was suffering tremendously. The patient heard the booster can be any, but the first 2 were supposed to be the same. This was because he chose Pfizer Covid Vaccine.  No concomitant medication was reported.   No treatment medication was reported.  The patient had battled with addictions and other dysfunctional behaviors. He had never felt anything past medication side effects from prescribed dose usage of psychiatric medication for treating untreatable depression and suffered a bit of those rather extreme side effects when heavily abusing methamphetamine daily. The patient had not even been using, had hardly smoked cannabis, hardly drank alcohol or cigarettes, had been very active, but he had been worsening and worsening even off of meth.  Company comment: This is a spontaneous case concerning a 26-year-old male patient with  medical history of depression, drug abuse and behavior disorder, who experienced the serious (medically significant) unexpected event deep vein thrombosis and the non-serious AESI COVID-19. The events occurred on an unknown date after the first dose of mRNA-1273 and after receiving the co-suspect product Tozineram as second dose of COVID-19 vaccination. DVT was reported on left leg: Clinical findings, diagnostic tests and treatment details were not provided. Event COVID-19 was described as a "long term COVID symptoms" and "repetitively infected with COVID". SARS-CoV-2 test was performed with negative result. Events seriousness captured as per IME list. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: Company comment: This is a spontaneous case concerning a 26-year-old male patient with  medical history of depression, drug abuse and behavior disorder, who experienced the serious (medically significant) unexpected event deep vein thrombosis and the non-serious AESI COVID-19. The events occurred on an unknown date after the first dose of mRNA-1273 and after receiving the co-suspect product Tozineram as second dose of COVID-19 vaccination. DVT was reported on left leg: Clinical findings, diagnostic tests and treatment details were not provided. Event COVID-19 was described as a "long term COVID symptoms" and "repetitively infected with COVID". SARS-CoV-2 test was performed with negative result. Events seriousness captured as per IME list. The benefit-risk relationship of mRNA-1273 is not affected by this report.