Crusted scalp, psoriasis on his chest, neck elbow, kneecap, scalp, encrusted scalp/patient had flare up of psoriasis and rashes all over his scalp; Uncomfortable extreme reaction of psoriasis, doctor diagnosed him with Sebo psoriasis; Red rash; Blister; Scalp felt tightening like someone was pulling on his head; Itching; worry; Entire body swipe out; skin bleeding; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PSORIASIS (Crusted scalp, psoriasis on his chest, neck elbow, kneecap, scalp, encrusted scalp/patient had flare up of psoriasis and rashes all over his scalp) in a 61-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 039821A and 021821A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Parapsoriasis (in the past and has been with dermatologist for 10 years.).   On 21-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 23-May-2021, the patient experienced SKIN EXFOLIATION (Entire body swipe out) and SKIN HAEMORRHAGE (skin bleeding). On 06-Jun-2021, the patient experienced PSORIASIS (Crusted scalp, psoriasis on his chest, neck elbow, kneecap, scalp, encrusted scalp/patient had flare up of psoriasis and rashes all over his scalp) (seriousness criterion medically significant), SEBORRHOEIC DERMATITIS (Uncomfortable extreme reaction of psoriasis, doctor diagnosed him with Sebo psoriasis), RASH ERYTHEMATOUS (Red rash), BLISTER (Blister), PAIN OF SKIN (Scalp felt tightening like someone was pulling on his head), PRURITUS (Itching) and ANXIETY (worry). The patient was treated with HYDROCORTISONE ongoing since an unknown date for Adverse event, at a dose of 2.5 mg; FLUOCINOLONE ACETONIDE ongoing since an unknown date for Adverse event, at a dose of 0.1 %, topical oil; TRIAMCINOLONE ACETONIDE ongoing since an unknown date for Adverse event, at an unspecified dose and frequency and SELENIUM SULFIDE (SELSUN BLUE) ongoing since an unknown date for Adverse event, at a dose of 2.5 %. At the time of the report, PSORIASIS (Crusted scalp, psoriasis on his chest, neck elbow, kneecap, scalp, encrusted scalp/patient had flare up of psoriasis and rashes all over his scalp), SEBORRHOEIC DERMATITIS (Uncomfortable extreme reaction of psoriasis, doctor diagnosed him with Sebo psoriasis), RASH ERYTHEMATOUS (Red rash), BLISTER (Blister), PAIN OF SKIN (Scalp felt tightening like someone was pulling on his head), PRURITUS (Itching), SKIN EXFOLIATION (Entire body swipe out), SKIN HAEMORRHAGE (skin bleeding) and ANXIETY (worry) outcome was unknown.            No concomitant drugs were provided. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Due to the severity, duration and lack of response to treatment the event psoriasis aggravated is considered serious due to medically significant criteria.   This case was linked to MOD-2021-207698 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 03-Jun-2021: Additional information received on 03-Jun-2021 contains significant Follow-up included updated the reporter's information, relevant medical history, treatment medications and newly added events. On 07-Jun-2021: Additional information received on 07-JUN-201 contains no new information. On 09-Jul-2021: Follow-up received included no new information. On 09-Jul-2021: Additional information received included additional event.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Due to the severity, duration and lack of response to treatment the event psoriasis aggravated is considered serious due to medically significant criteria.