Multiple sclerosis; Optic neuritis, inflamed optic nerve; Lost vision in eye; Active lesions on brain; Loss of right to be a mother; Loss of career, and healthy life; need help around house; This case was reported by a consumer and described the occurrence of multiple sclerosis in a female patient who received HAB (Twinrix) for prophylaxis.   Co-suspect products included hepatitis A and hepatitis B vaccine pre-filled syringe device (Twinrix Pre-Filled Syringe Device) injection syringe for prophylaxis.   Previously administered products included Twinrix with an associated reaction of fatigue (1st dose received on an unknown date, refer case US2022AMR097456).   On an unknown date, the patient received the 2nd dose of Twinrix and Twinrix Pre-Filled Syringe Device. On an unknown date, 5 days after receiving Twinrix and Twinrix Pre-Filled Syringe Device, the patient experienced multiple sclerosis (serious criteria GSK medically significant), optic neuritis (serious criteria GSK medically significant), loss of vision (serious criteria GSK medically significant), brain lesion, secondary infertility (female), quality of life decreased and activities of daily living impaired. On an unknown date, the outcome of the multiple sclerosis, optic neuritis, loss of vision, brain lesion, secondary infertility (female), quality of life decreased and activities of daily living impaired were not recovered/not resolved.   The reporter considered the multiple sclerosis, optic neuritis, loss of vision, brain lesion, secondary infertility (female), quality of life decreased and activities of daily living impaired to be related to Twinrix and Twinrix Pre-Filled Syringe Device.   This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences.   Linked case(s) involving the same patient:  US2022AMR097456   Additional Information: GSK Receipt Date: 15-JUN-2022 Reporter's Comments: For over 10 years the patient had been suffering with multiple sclerosis which was caused by Twinrix that the patient received after joining work in 2010. The patient had gone without therapies that could help with vaccine caused conditions, Optic neuritis was the initial clinical symptom that let the patient know something was wrong. The patient had MRI (magnetic resonance imaging) to check why she lost vision in eye and MRI revealed an inflamed optic nerve and active lesions on her brain as well which led to multiple sclerosis being diagnosed as well as the optic neuritis.  The patient stated that the things GSK vaccines took from her were priceless included loss of her career that she loved and miss to this day, loss of her human right to be a mother and bare her own kids, loss of the once in a lifetime chance to say goodbye to her own mother before she died, loss of over 10 plus years of her precious time in this life, loss of a healthy life full of promise only to be replaced by a shell of person who would never see their full potential realized, loss of the natural right to believe that her life did matter and loss of belief in the judicial systems. The patient needed help around house as she was disabled with no kids. The patient stated she would continue to suffer until the day she die as there was no cure for multiple sclerosis (MS), she Suggest one billion dollar for all she had taken away from her, all she had so inhumanely suffered/endured and unnecessarily gone through and would continue to go through due to GSK vaccines.  Only top decision-makers who had authority should respond to me via email please. Please end this travesty so that she could go on with what was left of her life.; Sender's Comments:  US-GLAXOSMITHKLINE-US2022AMR097456:Same reporter