After the third dose both armpits itched; caller's calves itched; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 65 year-old male patient received bnt162b2 (BNT162B2), administration date 23Oct2021 (Lot number: FF2590) at the age of 65 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "GERD" (unspecified if ongoing), notes: Relevant Medical History and Concurrent Conditions (not including reaction / event): , Comments: GERD. Concomitant medication(s) included: OMEPRAZOLE taken for gastrooesophageal reflux disease; FAMOTIDINE taken for gastrooesophageal reflux disease; LOVASTATIN. Vaccination history included: Bnt162b2 (Dose: 1, Lot: ER8730 , NDC and expiration date unknown, First Dose: left arm where he got the shot general aches in the joints muscle), administration date: 01Apr2021, when the patient was 64 years old, for COVID-19 immunization, reaction(s): "left arm where he got the shot general aches in the joints muscle", "First Shot: Chills and fever", "First Dose: Diarrhea", "First Dose: lost about 5 pounds", "First Dose: rose colored orange in his urine"; Bnt162b2 (Dose: 2, Lot: EW0162, NDC and expiration date unknown, Second dose: left arm injection site aches in his arm but not the whole body), administration date: 22Apr2021, when the patient was 64 years old, for COVID-19 immunization, reaction(s): "Second dose: left arm injection site aches in his arm but not the whole body", "Second dose: Chills and fevers", "Second dose: diarrhea", "Second dose: more sleepy and fatigued", "Second dose: more sleepy and fatigued"; Polio vaccine (When the caller was 5 or 6, in 1961 or 1962. The caller was involved in the original Polio vaccine in (Withheld) county there was a polio outbreak and he remembers standing with his neighbors getting a booster for Polio.), for Immunization. The following information was reported: PRURITUS (non-serious), outcome "unknown", described as "After the third dose both armpits itched"; PRURITUS (non-serious), outcome "unknown", described as "caller's calves itched".  Additional Information: Patient characteristics: Age at Time of Onset of Reaction / Event (number): 65. Age at Time of Onset of Reaction / Event (unit): Year. Body Weight (kg): 58.97. Height (cm): 168. Sex: Male. Relevant Medical History and Concurrent Conditions (not including reaction / event): GERD. Reaction/Event as Reported by Primary Source for Translation: First Dose: left arm where he got the shot general aches in the joints muscle. Outcome: Unknown. First Shot: Chills and fever. Outcome: Unknown. First Dose: Diarrhea. Outcome: Unknown. First Dose: rose colored orange in his urine. Outcome: Unknown. First Dose: lost about 5 pounds. Outcome: Unknown. Second dose: left arm injection site aches in his arm but not the whole body. Outcome : Unknown. Second dose: Chills and fever. Outcome: Unknown. Second dose: diarrhea. Outcome: Unknown. Second dose: more sleepy and fatigued. Outcome: Unknown. third dose: both armpits itched. Outcome: Unknown. Third dose: calves itched. Outcome of reaction/event at the time of last observation: Unknown. Date and Time of Start of Drug: 01Apr2021. Batch/lot number: ER8730. Dosage text: first dose; left arm; unknown dosage. Additional Context: The caller is calling about the COVID vaccination with the 2 shots and the first booster. The caller is strictly a Pfizer person. The caller has not reported this to VAERS, he has talked with them and asked them a bunch of questions. The VAERS agent said anything the caller tells Pfizer would be reported for his side effects. If the caller reports it to VAERS they wouldn't communicate it with Pfizer.  Event: The symptoms the caller had after his first dose all occurred over 7 days. The caller's symptoms started with left arm, where he got the shot, general aches in the joints muscles which decreased over 2-4 days. This event's onset started 2 days after he got the first dose with was on 01Apr2021. This symptom was still there but it decreased, this was the first wave. First Shot: Chills and fever. This started 3-5 days after the first dose and it decreased. The caller's fever was 98.5 degrees which is a lot because he is normally in the lower below 97 degree range or around there. Second dose: left arm injection site aches in his arm but not the whole body. The caller had a left arm ache but not general body ache with the first shot and only lasted a couple of days. Second dose: Chills and fevers. The caller's temperature. again was 98.5 degrees. First Dose: Received 01Apr2021, lot ER8730 NDC and expiration date unknown. Second Dose: Received 22Apr2021, lot EW0162, NDC and expiration date unknown. Third Dose: Received 23Oct2021, lot FF2590, NDC and expiration date unknown. The caller got this dose in his doctor's office. The first two doses were at a pharmacy it was a community. When the caller was 5 or 6, in 1961 or 1962. The caller was involved in the original Polio vaccine in county there was a polio outbreak and he remembers standing with his neighbors getting a booster for Polio. History: The caller took his normal medications. The caller started out with Nexium. The caller has been taking PPIs for over 30 years. It was hard to find Famotidine because it was being studied at one time.  No follow-up attempts are possible, No further information is expected. Sender's Comments: Linked Report(s) : US-PFIZER INC-202200519030 same product, patient, different AEs, different dose;US-PFIZER INC-202200518871 same product, patient, different AEs, different dose.