I started getting pains in stomach, pain in my intestine; I started getting pains in stomach, pain in my intestine; Diarrhoea; Exhausted and tired; I ended up having like a 101 temperature; Throwing up; Nausea; My stool turned yellow; my pee was dark; I had yellow eyes; This is a spontaneous report from a contactable consumer (patient). A 50-year-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE), dose 1 via an unspecified route of administration on 31Jul2021 (Batch/Lot Number: FA6780) at 50-years-old as DOSE 1, SINGLE for COVID-19 immunisation; adalimumab (HUMIRA), via an unspecified route of administration on 08Aug2021 (Batch/Lot Number: 1146119) at DOSE NUMBER UNKNOWN, SINGLE for arthritis.  Medical history included arthritis from an unknown date and unknown if ongoing. There were no concomitant medications. On unspecified dates, the patient experienced: I started getting pains in stomach, pain in my intestine (non-serious), diarrhoea (non-serious), exhausted and tired (non-serious), I ended up having like a 101 temperature (non-serious), throwing up (non-serious), nausea (non-serious), my stool turned yellow (non-serious), my pee was dark (non-serious), I had yellow eyes (non-serious); all of which required a physician office visit.    The patient stated, "I just wanted to let you guys know about the reaction possible with another drug." Name of the medication: patient stated, "Humira." The patient stated, "I think I had a reaction to it. I took my first shot (COVID vaccine) on 31Jul2021 so I waited a week and took a Humira shot 7 days later alright and then 3 days after that which was Wednesday night I started getting pains in stomach, pain in my intestine and I don't know I am 50, I had some kind of reaction then I ended up having like a 101 temperature, throwing up and then it disappeared so I don't know if taking Humira shot close to, taking Humira shot and having the COVID shot is good or bad. I talked to my doctor and he said there is, you can do it 7 days later, but I am actually had an adverse reaction to it I think." The patient confirmed the name of the products as COVID-19 Vaccine and HUMIRA vaccine.  When paraphrased, the patient stated, "I am having diarrhea, my stool turned yellow. I am going to my doctor tomorrow to talk to him about it. It seems like I had a like, it's like it could be before that like it's like after I took it. I had no reaction to the shot whatsoever I was perfectly fine with the vaccine, but I do not know taking HUMIRA and then working and then I ask 3 different doctors if it was okay to take it. I even called this HUMIRA pharmacy and they said there is no problem, but I don't know if it just by chance if ended up with 101 fever, throwing up and nausea." When informed about the Pfizer Medical Information Department for the concern, the patient stated, "Well, I will call my doctor tomorrow. I am just letting you know because research article, I have called to let you know I have something weird come up so. It was weird because I had the fever and the next day it was gone. I mean the next day I was exhausted and tired, but it was gone, the fever was gone." Anatomical site of vaccination (Pfizer covid-19 vaccine), consumer stated, "Right" Other medical condition, consumer stated, "I have arthritis, that's why I take HUMIRA and that's all." Treatment for the side effects, consumer stated, "No, like I said when I was taking HUMIRA straight up, I never had that kind of issue, when I was taking just straight Humira."  Upon follow-up on 18Aug2021, the patient stated, "I spoke to safety already. I had my first shot of the Pfizer COVID-19 vaccine on 31Jul2021. Couple of days later, I have noticed that on Wednesday I had pain in my intestine on Thursday night it got worst. Friday morning it was tremendous pain. I had 99.0 temperature which went to 101 and I vomited. I felt nauseous. I had chills. I had issues going to the rest room. My stool color had changed to yellow and my pee was dark. I got a COVID test done on Saturday which came back negative. I had no fever no other things. I had discomfort in my intestine, but it has subsided now. Monday, I went to see my doctor he said I was fine. I had yellow eyes. He did my blood work and liver panel with bilirubin. It all came back normal. My urine test came back normal. My color of stool is normal. I want to understand what may have caused the symptoms is it the fact that I've taken the HUMIRA shot with the vaccine. My doctor had advised me to take the HUMIRA shot seven days after the Pfizer COVID-19 vaccine, but I took it on the 8th day could that have caused me to feel this way."  The patient underwent lab tests and procedures which included blood work: normal on an unspecified date, temperature: 101 on an unspecified date, temperature: 99.0 on an unspecified date, color of stool: normal on an unspecified date, liver panel with bilirubin: normal on an unspecified date, COVID test: negative on 14Aug2021, urine test: normal on an unspecified date.  The action taken in response to the events for adalimumab was not applicable. The clinical outcome of the events: stool discoloration, gastrointestinal pain, pyrexia was recovered on an unspecified date, while the clinical outcome of the other events was unknown.