itching; tiredness; excessive urination; swelling of eyes; tight skin; puffy face; swelling all over her body; red bumps; This is a spontaneous report from a contactable parent reporting different events under the same suspect product for two patients. This is one of two reports: Reporting for 27-year-old female patient (daughter). A 27-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Batch/Lot Number: ER8732), first dose via an unspecified route of administration, administered in left arm on 15Apr2021 at 09:00 (at the age of 27-year-old) as dose 1, single for COVID-19 immunisation at church. Medical history included ongoing arthritis, ongoing drug hypersensitivity, ongoing rubber sensitivity. There were no concomitant medications. No Investigation Assessment was reported. Report is not related to a study or program. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. No additional vaccines administered on same date of the Pfizer suspect. No previous immunization with the Pfizer vaccine considered as suspect. No vaccine administered at military facility. The caller has three adult children who received the first dose of Pfizer COVID-19 vaccine on 15 Apr 2021 and two of the three children had reactions. One of the children is on the autism spectrum and the other just has orthopedic issues, but both had swelling all over their body and itching. This report is in regard to the caller's daughter, (Withheld). She confirms her daughter has orthopedic issues. She has a lot of allergies and is allergic to a lot of medications. They suspected she may have issues with the vaccine. She explains her children didn't have any noticeable reactions on site during their vaccination appointment which was like 9am, but by the time they got home, her daughter was like "Mom, I'm starting to itch all over", so she started her on the Benadryl. First, the caller tried to call the local health department and was directed to their family physician. So, she called the family physician, she reported it. She was told as long as it didn't feel like her daughter's throat was swelling or closing, to continue with the Benadryl every 8 hours and monitor her, and the same with her son. Her daughter started complaining of itchiness at like 4 am the next day, she came into the caller's room and was like "Mom, I'm itching like crazy and swollen all over". Her daughter showed the caller how tight her hands were and how puffy her cheeks were. As soon as their doctor's office opened the next morning, the caller did report both of her children's experience. She confirms her daughter had serious itching. The caller did not see any redness on her daughter or splotching, but her daughter was itchy. She could see some little red bumps on her daughter's skin, but nothing significant. The caller's daughter was also complaining about how tired she was. Her daughter said to the caller, "I was so tired I did not think I ate dinner". Her daughter came down at 4:00 to speak with the caller and her husband and tell them what she was experiencing. Her daughter said, "I just felt so tired all I could do was sleep". So, her daughter felt the tired sensation on day 1 of receiving the vaccine. Her daughter did tell the caller she had to pee a lot in the night. She confirms her daughter had no swelling of the eyes, but she did feel the swelling all over her body. Her daughter has a very fair complexion, so the caller could see how tight her skin was, how super puffy her face was, her stomach was. The caller could just see the swelling, just like with her son. It was very apparent. The caller's daughter did not complain that her throat was closing. She does have an EpiPen because she was allergic to everything under the sun or that one could think of. She clarified her daughter has seasonal allergies, any kind of bug allergy, she has had allergic reactions to medications. She mentions her daughter had an allergic reaction to a pain medication the doctor gave when she had her wisdom teeth pulled and she was taken to the hospital. Her daughter is allergic to Penicillin. She clarifies her daughter is allergic to any "-penicillin" or "-statins". No other details provided by caller. She got a bee bite sting, and that lead to hospitalization. Before her children got their injections, the caller asked was anything that they were doing have latex because all of her children have latex allergies as well. The caller was informed there was no latex was used at the vaccination site. Caller confirms she also has a latex allergy. Her daughter is still itching. It has lasted the entire week. She confirms all her daughter's symptoms are continuing today. She confirms, her daughter has no lip swelling, but she is still complaining of itchiness. She mentions her daughter is deathly afraid to get part 2 of the vaccine. She doesn't know what is going to happen. She did tell the nurse on site how she had an adverse reaction to the nasal flu vaccine. That was a hospitalization, too, but she had other flu injections with no reactions. When providing the Lot number, the caller mentions the second letter looks like a "K", but she believes the second letter is an "R" as she compares the Lot number to her son's vaccine record card. She confirms Lot number was " ER7832". Withheld has no medical history or takes anything that was related, but she takes amlodipine and metoprolol, but that's it, other than taking Zyrtec or Cetirizine if she has seasonal allergies. The doctor told her daughter to just take Tylenol for other discomforts/achiness she felt during these reactions. It was reported that the caller has three adult children who received the first dose of Pfizer COVID-19 vaccine on 15 Apr 2021 and two of the three children had reactions. Both children had swelling all over body, itching. She confirms her daughter had no swelling of the eyes, but she did feel the swelling all over her body. Her daughter has a very fair complexion, so the caller could see how tight her skin was, how super puffy her face was, her stomach was. The caller called the family physician, she reported it. She was told as long as it did not feel like her daughter's throat was swelling or closing, to continue with the Benadryl every 8 hours and monitor her, and the same with her son. The doctor told her daughter to just take Tylenol for other discomforts/achiness she felt during these reactions. Her daughter is still itching. It has lasted the entire week. She confirms all of her daughter's symptoms are continuing today. She confirms, her daughter has no lip swelling, but she is still complaining of itchiness. The events had not resulted in for death, life-threatening, prolonged hospitalization, disabling/incapacitating or Congenital anomaly/birth defect. Adverse event did not require a visit to emergency room and physician office, just a phone call to the doctor. No relevant tests were performed. The outcome of the event excessive urination was reported as unknown and rest all events were reported as not resolved.  No follow-up attempts are needed; information about lot/batch number cannot be obtained.