Dysautonomia in April after completing Moderna vaccines; Postural Orthostatic Tachycardia Syndrome  in April after completing Moderna vaccines.; This spontaneous case was reported by a patient family member or friend and describes the occurrence of AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia in April after completing Moderna vaccines) and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (Postural Orthostatic Tachycardia Syndrome  in April after completing Moderna vaccines.) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     Family history included Guillain Barre syndrome (other sister), Autoimmune disorder (family history) since an unknown date, Crohn's disease (brother) since an unknown date and Postural orthostatic tachycardia syndrome (Bother had POTS at the age of 17 years but did not had tachycardia or needed medication for it in the last 10 years.) since an unknown date.   On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In April 2021, the patient experienced AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia in April after completing Moderna vaccines) and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (Postural Orthostatic Tachycardia Syndrome  in April after completing Moderna vaccines.). At the time of the report, AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia in April after completing Moderna vaccines) and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (Postural Orthostatic Tachycardia Syndrome  in April after completing Moderna vaccines.) outcome was unknown.            Concomitant product use was not provided by the reporter.  Treatment information was not provided.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company comment: This spontaneous case concerns a female patient of unspecified age, with no medical history reported, who experienced the unexpected non-serious AESI event of Postural orthostatic tachycardia syndrome and unexpected nonserious event of Autonomic nervous system imbalance which occurred in context to a dose of mRNA-1273 vaccine. Latency cannot be assessed since vaccination date was not disclosed. No additional details of clinical course, concomitant medication was provided. The event outcome was unknown. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report. Events seriousness was assessed as per medical judgement and available information.   Reporter did not allow further contact; Sender's Comments: This spontaneous case concerns a female patient of unspecified age, with no medical history reported, who experienced the unexpected non-serious AESI event of Postural orthostatic tachycardia syndrome and unexpected nonserious event of Autonomic nervous system imbalance which occurred in context to a dose of mRNA-1273 vaccine. Latency cannot be assessed since vaccination date was not disclosed. No additional details of clinical course, concomitant medication was provided. The event outcome was unknown. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report. Events seriousness was assessed as per medical judgement and available information.