A report was received from a health care professional on 11/19/03 concerning a female vaccinee more than 65 year old who experienced sniffles, cough, fever, and sore throat requiring hospitalization up to 1 week after receiving Fluvirin on approximately 11/6/03. On an unspecified date, up to one week after vaccination, the vaccinee experienced sniffles, cough, fever, and sore throat. The results of a chest x-ray was taken on an unspecified date were negative. The outcome of the event was reported as unknown. There was insufficient information to determine the reporter's causality assessment. Follow up pending. Follow up on 03/22/04 states: " Update 1, 11/26/03: A follow up report was received from a healthcare professional indicating that a 71 year old female vaccinee experienced oxygen saturation of 84% on 2 litres of oxygen, oximeter reading of 89% congestion, wheezing, and fever which led to hospitalization and which was considered life threatening after receiving Fluvirin on 11/14/03.  The vaccinee has a history of bipolar depression, hypertension, congestive heart failure, nocturnal dyspnea, atrial tachycardia, and generalized weakness from 01/14/03 and breast cancer unspecified allergies anxiety from a date not specified. The vaccinee is a smoker consuming 2 to 3 packets per day for 50 to 60 years and is on nasal oxygen as required. Concomitant medications taken included tamoxife, foxofenadine hydrochloride, valproate semisodium, lorozepam, lansoprazole, hydrocodine bitartrate with acetaminophen, and forusmide. On 11/16/03 an oximeter read 89% on 2 litres of oxygen. On 11/17/03 the vaccinee experienced a temperature of 100.1 degrees Fahrenheit. The vaccinee experienced wheezing and congestion with an oxygen saturation of 84% on two litres of oxygen on an unspecified date. The vaccinee was hospitalized on 11/17/03 and treated with increased oxygen. The vaccinee was discharged on 11/21/03.  The outcome of the events was not reported. Update 2, 03/01/04: Further information received from a health care professional indicated that the vaccinee had an oxygen saturation of 89% at rest on 11/16/03 and a temperature of 99.6 degrees Fahrenheit increasing to 100.1 degrees Fahrenheit on 11/17/03.  The vaccinee's symptoms started approximately 48 hours following Influenza vaccination on 11/16/03.  The vaccinee was discharged from hospital on 12/18/03.  The vaccinee also has a history of renal failure, coronary artery disease, orthropnea and allergies to Augmentin, hepatin and sulfa. Further concomitant medications taken included digorin, diltioten hydrochloride, lovothyroxine sodium and iprotropium in combination with salbutamol. The vaccinee is also receiving oxygen 1-2L to maintain saturation greater than 90%.  Follow up pending." Update 1. 26 November 2003: A follow up report received from a health care professional indicating that a 71-year-old female vaccinee experienced oxygen saturation of 64 on 2 liters of oxygen, oximeter reading of 89 %, congestion wheezing and fever which led to hospitalisation and which was considered life threatening after recieving FLUVIRIN on 14 November 2003. The vaccinee has a history of bipolar depression, hypertension, congestive heart failure, nocturnal dysphea, atrial tachycardia, and generalise weakness from 14 January 2003 and breast cancer, unspecified allergist and anxiety from a date not specified. The vaccinee is a smoker consuming 2 to 3 packets per day for 50 to 60 years and is on nasal oxygen as required. Concomitant medications taken included tamoxifcn, fexofenadine hydrochloride, valproate semiaodium, lorazepam, lansoprazole, hydrocodone bitartrate with actaminophen, and chrotemide. On 16 November 2003 an oximeter read 89% on 2 liters of oxygen. On 17 November 2003 the vaccinee experienced 1 temperature of 100.1 degrees Fareneit. The vaccinee experienced wheezing and congestion with an oxygen saturation of 84% on two liters of oxygen on an unspecified date. The vaccinee was hospitalised on 17 November 2003 and treated with increased oxygen. The vaccinee was discharged on 21 November 2003. The outcome of the events was not reported. Cross reference with: PJP-2003-01129, PJP-2003-01118, PJ-2003-01119, PJP-2003-01120, PJP-2003-01121, PJP-2003-01122, PJP-2003-001123, PJP-2003-01124, PJP-2003-01125, PJ-2003-01127, PJP-2003-01128, PJP-2003-01117.