SLIGHTLY SORE ARM; This spontaneous report received from a patient concerned an adult female of unspecified age and ethnicity. The patient's weight was 265 pounds, and height was 66 inches. The patient's past medical history included: infections, hospitalization (patient was never hospitalized in life, might be just 1 time) and concurrent conditions included: polyethylene glycol allergy (the patient had a very severe allergy to polyethylene glycol, the patient found out the allergy to polyethylene glycol accidentally, because the patient was given a samples of eyedrop from doctor, after use patient eyes started swelling up, eyelids swell up like pillows and turned red and closed to the point could not see through them. The ingredient of Blink eyedrops is polyethylene glycol), chronic asthma (was taking medications for asthma), sleep apnea (had a BiPap (bilevel positive airway pressure) machine for sleep, patient requires a BiPap instead of CPAP (continuous positive airway pressure), respiratory issues), Bipap user, lung scarring (from previous infections like had whooping cough and exposed to a lot of second-hand smoke in life, not hospitalized, just in the emergency room), non-smoker (exposed to a lot of second-hand smoke. Patient had a neighbor that smoked heavy and smoke permeated into patient's bathroom. Patient felt better that she moved out), non alcohol user, obese (get sick easily), autoimmune issues, vitamin d3 deficiency (then corrected, was taking Vitamin D3, weekly high dose), fatty liver (not sure what it was from, might be toxins, nothing significant), nodules on lungs (a few nodules on lungs, followed them up and it was not anything to worry about), kidney cyst (found something on kidney (cyst), but there was no any concern, otherwise, liver and kidney functions normally), menopause (gained weight after menopause and had issues with degenerative disk disease and arthritis type symptoms, so makes it hard to move), drug allergy (Albuterol, thimerasol and potassium chromate), latex allergy, sulfa allergy, gluten allergy, dairy allergy, allergic to potatoes, food allergy (allergic to green beans), allergic to shrimp and other pre-existing medical conditions included: The patient had no any symptoms of positive COVID-19 disease prior to vaccination, had no pre-existing acute illness 30 days prior to vaccination. The patient had family history (mother's side) of lot of heart issues, bad/gasping snoring. They probably had sleep apnea and most of mother's side died before 70 due to heart problem. Patient had a lot of history of allergy to vaccine, drug, or food. Patient went to an allergist and was tested and given a list of allergens and seasonal allergies. The patient was not pregnant at the time of vaccination. The patient experienced fatigue, muscle aches and pain in arm when treated with varicella zoster vaccine for prophylactic vaccination, and more reactions (unspecified) when treated with influenza vaccine for prophylactic vaccination. The patient recovered (went away in 3 to 4 days) from fatigue, muscle aches and pain in arm and outcome of the more reactions was not reported. The patient received covid-19 vaccine ad26.cov2.s (dose number in series 1) (suspension for injection, route of admin, and batch number were not reported, expiry: unknown) dose was not reported, 1 total administered on 28-APR-2021 for covid-19 prophylaxis.  On an unspecified date in 2021, following vaccination with first dose of covid-19 vaccine ad26.cov2.s, the patient experienced slightly sore arm (dose number in series 1). The outcome of the slightly sore arm was not reported. The patient received covid-19 vaccine ad26.cov2.s (dose number in series 2) (suspension for injection, route of admin, and batch number were not reported, expiry: unknown) dose was not reported, 1 total administered on 25-OCT-2021 for covid-19 prophylaxis. The batch number was not reported and has been requested. Age at time of vaccination 60 years old. Concomitant medications included levosalbutamol hydrochloride (Xopenex) and montelukast sodium (Singulair) for chronic asthma, ibuprofen for pain, and colecalciferol (vitamin D3) for vitamin d3 severe deficiency.  On an unspecified date, the patient experienced slightly sore arm (dose number in series 2). The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The outcome of slightly sore arm was not reported. This report was non-serious.  This case, involving the same patient is linked to 20220943780 and 20220956144.