stroke/MRI showed small stroke to the mid brain; aphasia/could not find the words he wanted; head felt cloudy; he did not eat; This spontaneous case was reported by a consumer and describes the occurrence of CEREBROVASCULAR ACCIDENT (stroke/MRI showed small stroke to the mid brain) and APHASIA (aphasia/could not find the words he wanted) in a 79-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 939904, 032M20A and 024M21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Immunodeficiency, Giant cell arteritis, Childhood asthma, Blood cholesterol abnormal and Blood pressure abnormal. Concomitant products included PREDNISONE for Giant cell arteritis.   On 11-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 11-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 11-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 11-Nov-2021, the patient experienced FEELING ABNORMAL (head felt cloudy) and HYPOPHAGIA (he did not eat). On 12-Nov-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced CEREBROVASCULAR ACCIDENT (stroke/MRI showed small stroke to the mid brain) (seriousness criteria hospitalization and medically significant) and APHASIA (aphasia/could not find the words he wanted) (seriousness criterion hospitalization). The patient was hospitalized from 12-Nov-2021 to 13-Nov-2021 due to APHASIA and CEREBROVASCULAR ACCIDENT. The patient was treated with HEPARIN for Stroke, at an unspecified dose and frequency. At the time of the report, CEREBROVASCULAR ACCIDENT (stroke/MRI showed small stroke to the mid brain), FEELING ABNORMAL (head felt cloudy) and HYPOPHAGIA (he did not eat) outcome was unknown and APHASIA (aphasia/could not find the words he wanted) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 12-Nov-2021, Magnetic resonance imaging: abnormal (abnormal) showed small stroke to the mid brain. On an unknown date, Blood cholesterol: normal (normal) cholesterol had been controlled and the level was low. On an unknown date, Computerised tomogram: normal (normal) normal.         Other concomitant medications included was unspecified cholesterol and blood pressure medications. Patient stated, his cholesterol and blood pressure was under control. When the patient got home after receiving the shot, his head felt cloudy, so he did not eat, went right to bed and slept the whole night. He assumed this happened within an hour after the shot as he received the vaccine in the early evening. The next day, he went to work, but when talking to his colleagues, he could not find the words he wanted, like an aphasia. He called his doctor and went to the emergency room on 12-Nov-2021, was hospitalized and was discharged on 13-Nov-2021. He got a CAT scan, which turned out normal, and MRI, which showed small stroke to the mid brain. He also suspected that it could have been due to cholesterol, but his cholesterol was controlled and the level was low. He had no idea what caused this. Since hospitalization, his speech improved. Within a next month, he would have his heart checked and get a stress test. He was a physical therapist, still worked, and never had stroke before. He was treated with heparin, but not sure of the full treatment.  This case concerns a 79-year-old male patient with relevant medical history of Giant Cell Arteritis, who experienced the unexpected serious event of Aphasia, and serious adverse event of special interest Cerebrovascular Accident. The events, which caused hospitalization for the patient, occurred approximately 1-2 days after receiving the third dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the third dose was disclosed. Patient was hospitalized for one day and was discharged improved, diagnostics revealed abnormal MRI findings. The reporter assessed the events as possible. The medical history of Giant Cell Arteritis remains a confounder for Cerebrovascular Accident. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Sender's Comments: This case concerns a 79-year-old male patient with relevant medical history of Giant Cell Arteritis, who experienced the unexpected serious event of Aphasia, and serious adverse event of special interest Cerebrovascular Accident. The events, which caused hospitalization for the patient, occurred approximately 1-2 days after receiving the third dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the third dose was disclosed. Patient was hospitalized for one day and was discharged improved, diagnostics revealed abnormal MRI findings. The reporter assessed the events as possible. The medical history of Giant Cell Arteritis remains a confounder for Cerebrovascular Accident. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.