it made her tired; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program. The reporter is the patient.  A 67 year-old female patient received bnt162b2 (BNT162B2), administration date 14Mar2022 (Lot number: FK9895) as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Immunocompromised" (unspecified if ongoing); "Bladder cancer" (unspecified if ongoing); "Hypersensitivity" (unspecified if ongoing); "Asthma" (unspecified if ongoing); "lower right lung scar tissue from the covid", start date: Feb2021 (unspecified if ongoing); "COVID-19", start date: Feb2021 (unspecified if ongoing), notes: this was prior to getting the first and second dose, she was hospitalized and almost died.; "lumpectomy" (unspecified if ongoing); "Rheumatoid arthritis" (unspecified if ongoing), notes: Rheumatoid arthritis for which she takes methotrexate, 2.5mg; "covid pneumonia" (unspecified if ongoing), notes: she had double covid pneumonia; "used to be a smoker" (unspecified if ongoing), notes: She also used to be a smoker but quit 5 years this Sep; "allergic to mold" (unspecified if ongoing); "She is allergic to mold, oak trees, maple trees, and dust, clarifying mostly environmental allergies" (unspecified if ongoing); "She is allergic to mold, oak trees, maple trees, and dust, clarifying mostly environmental allergies" (unspecified if ongoing). Family history included: "Breast cancer" (unspecified if ongoing), notes: for the breast cancer they did a lumpectomy. Concomitant medication(s) included: METHOTREXATE taken for rheumatoid arthritis; PREDNISONE; TRELEGY; FOLIC ACID; VITAMIN B3; CALCIUM. Vaccination history included: Bnt162b2 (First Dose, single, Lot EW0178, she also provides WA606174 from her card, Expiry Unknown.), administration date: 27May2021, for Covid-19 Immunization, reaction(s): "COVID-19"; Bnt162b2 (Second Dose, single, Lot EH6181, Expiry Unknown), administration date: 17Jun2021, for Covid-19 Immunization, reaction(s): "COVID-19". The following information was reported: FATIGUE (non-serious) with onset Mar2022, outcome "unknown", described as "it made her tired". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: It was reported that, she already got the 3rd booster shot yesterday. She's already caught Covid Omicron with no symptoms. When she got Covid the first time it almost killed her, she was in the hospital for a month and a half. After that she got 2 Covid vaccine shots, then 6 months after getting the 2nd Covid shot, he got the Covid omicron virus. The doctor asked her what symptoms she had and she told him she had none, she contracted Covid from a kid that she was babysitting. They did a PCR and rapid test and she was positive. Caller stated that she noticed with the booster shot that it made her tired. Caller stated that when she got Covid the last time she didn't even sneeze or cough, she thinks that when she had it bad the first time, the doctor tried Mucinex on her and gave medications that made her cough. With the first time she had Covid, she would have been okay, she only lost smell with first one, and was then in the ICU. Prior to getting the first and second dose, she was hospitalized and almost died. She tested positive for Covid virus on 13Dec2021, they gave her the Monoclonal Antibody through IV on 14Dec2021, she remembers this because she went into the Emergency room on 13Dec2021 and 17 hours later they finally gave her the monoclonal antibodies at 10AM on 14DEC2021. On 13Dec2021 they did a PCR and Rapid test and both were positive, however she had no symptoms even though she was positive for the omicron virus. Medical conditions: Yes, She is Immunocompromised. She has had bladder and breast cancer, for the breast cancer they did a lumpectomy, that one was easy, her body just had to get rid of the estrogen, however she was over treated and after the breast cancer she got Rheumatoid arthritis for which she takes methotrexate, 2.5mg. She was also on Prednisone once a day, but they cut it down now to 2.5mg every 2 days. Caller stated that her knees are hurting now, since its her second day off of it. Caller clarified that she was instructed to not take Methotrexate a week before and a week after getting the Booster, this is now the week after. They told her she can still continue the Prednisone with getting the booster because the dose is too low and wont bother her getting the booster. Caller states that instead of listening to the doctor she didn't take either. Caller states that she is also on 1 folic acid a day, vitamin B3, and calcium. She gets a Prolia shot once a month. The Methotrexate is 6 tablets once a week. Caller has no Lot or Expiry for Methotrexate and Prednisone since they are dispensed in pharmacy vials.   No follow-up attempts are possible. No further information is expected.