Skin becomes red when touched; Skin becomes itchy when touched; Skin becomes swollen when touched; Swelling on the back of her neck; Skin rashes all over the body/quite bad rash; This spontaneous case was reported by a consumer and describes the occurrence of ERYTHEMA (Skin becomes red when touched), PRURITUS (Skin becomes itchy when touched), SKIN SWELLING (Skin becomes swollen when touched), SWELLING (Swelling on the back of her neck) and RASH (Skin rashes all over the body/quite bad rash) in a 46-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 041J21A, 033C21A and 051C121A) for COVID-19 vaccination.     The patient's past medical history included COVID-19 (a severe Case of COVID, and for this reason she received Monoclonal antibodies on 12-Feb-2021) on 05-Feb-2021.   On 14-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 11-Jun-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Feb-2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 03-Mar-2022, the patient experienced ERYTHEMA (Skin becomes red when touched), PRURITUS (Skin becomes itchy when touched), SKIN SWELLING (Skin becomes swollen when touched), SWELLING (Swelling on the back of her neck) and RASH (Skin rashes all over the body/quite bad rash). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Skin rash, at an unspecified dose and frequency; EPINEPHRINE (EPIPEN) for Skin rash, at an unspecified dose and frequency and CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) at an unspecified dose and frequency. At the time of the report, ERYTHEMA (Skin becomes red when touched), PRURITUS (Skin becomes itchy when touched), SKIN SWELLING (Skin becomes swollen when touched), SWELLING (Swelling on the back of her neck) and RASH (Skin rashes all over the body/quite bad rash) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: normal (normal) did not find something wrong.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered ERYTHEMA (Skin becomes red when touched), PRURITUS (Skin becomes itchy when touched), SKIN SWELLING (Skin becomes swollen when touched), SWELLING (Swelling on the back of her neck) and RASH (Skin rashes all over the body/quite bad rash) to be related.    The patient had no known allergies to medications, food and other products.The patient had no medical history related to reported adverse event at the time of vaccination.  The patient did not take any concomitant medication.  Patient received the booster dose.  It was reported that the patient thought the reported events were an allergic reaction and mentioned her skin basically becomes red instantly as soon as she touched it, skin also becomes itchy and swollen once it was touched. these symptoms were on patient's entire body. It was mentioned that the rash was quite bad and for this reason patient visited the hospital where the patient was provided with Benadryl and Epipen, but treatment did not seem to work for the patient. Patient also visited the allergist and had blood work done, but did not find something wrong. Patient's doctor informed her that symptoms might be an adverse event of the Moderna COVID 19 vaccine. The patient will have an appointment with the dermatologist on May-2022.