friends parents took the COVID vaccine and passed away; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP) from medical information team.  A male patient received BNT162b2 (BNT162B2), as dose number unknown, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: DEATH (death, medically significant), outcome "fatal", described as "friends parents took the COVID vaccine and passed away". The date and cause of death for the patient were unknown. It was not reported if an autopsy was performed. Clinical course: Case reported as non serious. Caller has not had the COVID vaccine and is concerned. She wants to know how does the vaccine works with new variants of COVID. She wants to understand the biochemistry. She compares it to the flu vaccine and how the influenza virus changes yearly. She states COVID is on the 7th mutation & Pfizer created a vaccine that was for the 1st variant. She notes that Omicron has 47 different mutations and how one would make a vaccine that is effective against the other variants. She states there are no vaccines that they are aware of that can do this but yet Pfizer "claims" that the vaccine does. Caller states that unless they "created this robotic vaccine, there is no way." She states that they are in the medical feild and they do not feel as though it makes sense how the biochemistry works for the product. Caller stated that her father did not feel as though it makes any sense and thus they have not received the vaccine at this time. Caller queried the biochemistry of the product and wants to know if they are taking the mRNA from the "crown." She states the only thing that does change is the crown and wants to know if this is where it is coming from. Caller notes that the news is stating that the product is only 10% effective with the "new variant." She states that is "bearly making it." She states they do not understand how it is working and they are confused and despite their medical back ground, they do not feel as though it makes sense from a biochemistry standpoint. Caller stated her friends parents took the COVID vaccine and passed away. She states they were mad because they followed "all the things" and they still passed away. She wants to know how come Pfizer is not liable for putting a product like this on the market and patients passing away. She states she spoke with a lawyer and the lawyer advised them that Pfizer was not liable. Caller wants to know who cannot take the product. She wants to know if there is an allergy test that can be done prior to taking the product. She spoke with her provider regarding this and they advised to contact either Pfizer or Moderna. Advised the caller that she would have to speak with the HCP regarding testing available for such request, Pfizer MI does not have guidance on said testing or availability of such. Advised that we would be able to provide her with a list of ingredients to then further review with her HCP.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200650352 Same reporter/vaccine/event, different patient; Reported Cause(s) of Death: friends parents took the COVID vaccine and passed away