Chest pain; Heart palpitation; Shortness of breath; Rash/Started to face; Asthma; Nodule grew the lung; Hives; The initial case was missing the following minimum criteria: no adverse effect. Upon receipt of follow-up information on 20Mar2023, this case now contains all required information to be considered valid.  This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 52-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 23May2021 at 08:00 as dose 1, single (Lot number: EW0169) at the age of 52 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "thyroid" (ongoing), notes: Thyroid; "penicillin Allergy" (unspecified if ongoing); "COVID-19" (unspecified if ongoing), notes: Prior to vaccination, was the patient diagnosed with COVID-19: Yes; "Cholesterol" (ongoing). Family medical history relevant to Adverse events (AES): Grandmother-Diabetes, Mom-High blood pressure, Dad-Cancer, Brother-Diabetes, High blood pressure. Concomitant medication(s) included: ARMOUR THYROID oral taken for thyroid disorder (ongoing); ATORVASTATIN oral taken for blood cholesterol (ongoing). The following information was reported: ASTHMA (non-serious) with onset 01Jun2021, outcome "not recovered"; CHEST PAIN (non-serious) with onset 01Jun2021, outcome "not recovered"; PALPITATIONS (non-serious) with onset 01Jun2021, outcome "not recovered", described as "Heart palpitation"; RASH (non-serious) with onset 01Jun2021, outcome "not recovered", described as "Rash/Started to face"; DYSPNOEA (non-serious) with onset 01Jun2021, outcome "not recovered", described as "Shortness of breath"; URTICARIA (non-serious) with onset Jun2021, outcome "not recovered", described as "Hives"; PULMONARY MASS (medically significant) with onset Jun2021, outcome "not recovered", described as "Nodule grew the lung". The events "nodule grew the lung", "chest pain", "heart palpitation", "shortness of breath", "rash/started to face", "hives" and "asthma" required physician office visit. The patient underwent the following laboratory tests and procedures: Angiogram: (28Jun2021) negative, notes: The procedure was negative; (05Nov2021) Unknown results, notes: Comments: dr. concluded not heart; Computerised tomogram: (28Jun2021) nodule showing on CAT scan; Magnetic resonance imaging: (28Jun2021) Unknown result, notes: Further test; (15Oct2021) Unknown result; Positron emission tomogram: (15Oct2022) Comments: Nodule increased; (23Jan2023) Comments: Nodule increased; Pulmonary function test: (15Oct2021) Unknown result; (15Oct2022) Unknown result; X-ray: (15Oct2021) Comments: Nodule of lungs; Blood test: (unspecified date) Unknown results; Allergy test: (unspecified date) Unknown results; Tuberculin test: (unspecified date) Unknown results; vein testing: (unspecified date) Unknown results; (unspecified date) Unknown results.  Clinical course: Vaccination facility type was reported as Public health clinic. In Jun2021, after 1st vaccine started to experience chest pain, shortness of breath, heart palpitations, hives. I went to my Dr. in Jun2021 and was sent to Cardiologist. I went the tests and CAT scan. There was a nodule showing on CAT scan. I was then sent for an angiogram to determine if there were any blockages. The procedure was negative. I went back to primary care was sent to lung specialist. I went the blood tests, Allergy test, TB tests, vein testing, XRAY, MRI, CT scan, PET scan. The nodule grew the lung or felt. I should see a surgeon. Now I am schedule for a surgery 11Apr2023. I never had asthma or breathing issues. All started after vaccine. I went for two and my symptoms did not improve.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300082818 Same reporter, patient/ different dose;