anxiety has been raised; wanted to make sure that he did not render the efficacy of the Covid-19 vaccine ineffective by not really sure if he took an Ibuprofen the night before his first dose of the vaccine; This is a spontaneous report received from contactable other HCP. This other HCP male patient an unspecified age reported for himself that who received bnt162b2 (BNT162B2) solution for injection, dose 1 (Batch/Lot Number: EN6205) via an unspecified route of administration in arm left on 08Mar2021 as dose single for covid-19 immunisation; ibuprofen (IBUPROFEN), (Batch/Lot number was not reported) via an unspecified route of administration from an unspecified date to an unspecified date, at for arthralgia. The patient medical history and concomitant medications were not reported. Reporter stated that he was an other health care provider and is called about his own experience. Reporter stated that he received his first Pfizer vaccine on 08Mar2021, verified that he was speaking about the Pfizer Covid-19 vaccine. Reporter stated that his second dose is coming up at the end of the month on 29Mar2021.nReporter stated that his anxiety has been raised. Reporter inquired if he took ibuprofen the night before, has he rendered the Covid-19 vaccine ineffective. Reporter further inquired why did no one ever mention this to him in the process of preparing for shot. Reporter stated that he was trying to see where he stands, stating that this was anxiety provoking and that he had no way of knowing the information regarding ibuprofen and the Covid-19 vaccine. Reporter reported that he has had anxiety created after seeing a blurb on the news a couple of days ago that you should not take Ibuprofen prior to getting the Covid-19 vaccine. Reporter stated that he further investigated this claim via regulatory authority guidelines and stated it was something that he didn't know and hadn't come across in his professional practice. Reporter stated that he knows that he didn't take any ibuprofen the morning of 08Mar2021 before his vaccination, but he can't say for certain that he didn't take ibuprofen the night before. Reporter stated that he definitely took ibuprofen after he got home on 08Mar2021. Reporter reported that he always takes ibuprofen after the flu shot, stating that as an health care provider he knows there is going to be some inflammation at the injection site. Reporter not queried on concomitant products, medical history, or investigations as this was an MI request only. PSCC Communication: MI experiencing high call volume, so caller was placed in the MI queue at his request. Reporter was provided with MI phone number before transfer, (Phone number) option 3. The reporter, (Name withheld), a health care provider called to ask and wanted to make sure that he did not render the efficacy of the Covid-19 vaccine ineffective by not really sure if he took an Ibuprofen the night before his first dose of the vaccine was given due to a shoulder pain incurred from an injury. (Name withheld) first dose of the vaccine was given on 08Mar2021. Medical Information: Were no unaddressed medical questions referred or forwarded to Medical Information. Outcome of the events was unknown