the pressure in her eye and the inflammation, they are going down; the pressure in her eye and the inflammation, they are going down; have the eye stroke and it caused a partial loss of vision in her right eye; have the eye stroke and it caused a partial loss of vision in her right eye; have the eye stroke and it caused a partial loss of vision in her right eye; This is a spontaneous report from a contactable consumer (patient) via a Pfizer sponsored program. A 60-year-old female patient received the second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE), via unknown route of administration on 26Feb2021 (Lot Number: EN6200) at single dose for COVID-19 immunisation. Co-suspect drug included estradiol (ESTRING) Vaginal delivery system from unknown date via unknown route of administration at 1 ring every 12 weeks as directed (lot number: VK993A, Expiry Date: 30Sep2021) for drying out down. Medical history and concomitant medications were reported none. Historical vaccine included first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE) via unknown route of administration on 05Feb2021 (Lot Number: EL9265) at single dose for COVID-19 immunisation. Patient stated that she used Estring and that she had an eye stroke. She had been using this estradiol product for quite a while. She did also have the two Pfizer COVID vaccines. She did have the eye stroke on 29May2021 and it caused a partial loss of vision in her right eye. The eye stroke and partial loss of vision occurred after the COVID vaccines and after use of the estradiol product. She gave permission to leave a voice message if needed because she did not answer the phone. There were so many people trying to rip you off. She was still experiencing the effects of this and she was under doctors care for it. She saw the doctor yesterday and as far as the pressure in her eye and the inflammation, they were going down. They did some more x-rays and her eye had gotten a little better but she did not go back for another follow up until 16Aug2021. Her doctor told her that sometimes it could take a while for it to come back, if her vision would come back at all. She was hoping and praying that it would though. Patient had been using estradiol about 2 to 3 years. When asked about the indication, Jokingly she said old age, She clarified and said that she was actually drying out down there and that was when her doctor first inserted one in a couple years prior to the report. About the COVID vaccines, Probed for NDC, lot number and expiry date and patient did not see the NDC or expiry date on the COVID vaccination record card. Therapy start date populated as the date for the callers first COVID vaccine and the therapy stop date populated as the date for the callers second COVID vaccine. She was scared after the eye stroke. She had heard of some people having strokes after the COVID vaccines but she did not know what kind of stroke or whatever that they have had. Probed for further details on the callers statement regarding other having strokes and she said that this was something that she had just seen on the news where they had reported that some people were having strokes and stuff from certain vaccines but she was unsure if it was the Pfizer one. She was kind of asking if a question on if Pfizer had anything like this that had been reported. Patient was a 60 years old female who experienced a right eye stroke on 29May2021. She received the Pfizer Covid-19 vaccine in Feb2021. She had been taking estradiol for years and was taking it at the time she was vaccinated. Patient asking have eye stokes been reported after receiving the Pfizer COvid-19 Vaccine. She had heard of people on the news experiencing a stoke but they did not specify what kind of a stroke. The action taken in response to the events for estradiol was unknown. The outcome of the events was recovering.  Follow-up attempts are completed. No further information is expected.