Facial flushing; It appeared like someone slapped my face looked like burn from my cheek to forehead and to my face; whole right side of face was red; My face is now peeling/Face is peeling; Just felt warm; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 69-year-old female patient received bnt162b2 omi xbb.1.5 (COMIRNATY (2023-2024 FORMULA)), on 03Oct2023 as dose 6 (booster), single (Batch/Lot number: unknown) at the age of 69 years intramuscular, in left arm for covid-19 immunisation. The patient's relevant medical history was not reported. The patient took concomitant medications. Vaccination history included: bnt162b2 (Around 11AM , DOSE 1, SINGLE, Batch/Lot number: EN6200, Anatomical location: Left arm , Route of Administration: intramuscular), administration date: 01Mar2021, for COVID-19 immunization; bnt162b2 (Around 11AM , DOSE 2, SINGLE, Batch/Lot number: ER8733, Anatomical location: Left arm , Route of Administration: intramuscular), administration date: 25Mar2021, for COVID-19 immunization; bnt162b2 (About 10AM , DOSE 3 (BOOSTER), SINGLE, Anatomical location: Left arm , Route of Administration: intramuscular), administration date: 25Sep2021, for COVID-19 immunization; bnt162b2 (At Morning time, DOSE 4 (BOOSTER), SINGLE, Batch/Lot number: FJ4991, Anatomical location: Left arm , Route of Administration: intramuscular), administration date: 09Apr2022, for COVID-19 immunization; bnt162b2;bnt162b2 omi ba.4-5 (At Morning time, DOSE 5 (BOOSTER), SINGLE, Batch/Lot number: GH9703, Anatomical location: Left arm , Route of Administration: intramuscular), administration date: 22Oct2022, for COVID-19 immunization. The following information was reported: FLUSHING (non-serious) with onset 03Oct2023, outcome "unknown", described as "Facial flushing"; SKIN BURNING SENSATION (non-serious) with onset 03Oct2023, outcome "not recovered", described as "It appeared like someone slapped my face looked like burn from my cheek to forehead and to my face"; FEELING HOT (non-serious) with onset 03Oct2023, outcome "unknown", described as "Just felt warm"; SKIN EXFOLIATION (non-serious) with onset 03Oct2023, outcome "unknown", described as "My face is now peeling/Face is peeling"; ERYTHEMA (non-serious) with onset 03Oct2023, outcome "not recovered", described as "whole right side of face was red". The events "facial flushing", "it appeared like someone slapped my face looked like burn from my cheek to forehead and to my face", "whole right side of face was red", "my face is now peeling/face is peeling" and "just felt warm" required physician office visit.  Additional information: Patient stated that she didn't have hives. It appeared like someone slapped her face looked like burn from her cheek to forehead and to her face. This happened in the afternoon after she received the vaccine. She called her doctor also. The symptoms subsided but came back. Her face was now peeling. She did not have any pustules or bumps. Face was peeling at this point, was experiencing a little bit of redness yesterday, but noticed today that now face, especially forehead, was peeling. Seemed like once gets warm water on face, flushing begins again, seemed like activating histamines. Patient was administered dose 6 at about 10:15AM. From years ago having had hives over an event, patient had asked physician to prescribe the generic of Atarax, clarified and confirmed hydroxyzine. Caller had been on a very low dose statin for probably a month and a half and knew could develop facial rashes with that too. Caller was on Crestor Dosage was 5mg, so lowest dosage, tablet.   The information on the batch/lot number for bnt162b2 omi xbb.1.5 has been requested and will be submitted if and when received.