patients appointment is the same day as Covid vaccine, 28Feb2021; States he was told by the physician that it is possible the Covid vaccine is note safe; them on Saturday and his kinase was 1015; he wasn't feeling well; nausea; unable to articulate how he feels due to depressed ability to speak; panic; anxiety; This is a spontaneous report from a contactable pharmacist. A 46-years-old male patient received bnt162b2 (BNT162B2, PFIZER-BIONTECH COVID-19 mRNA VACCINE; Formulation: Solution for injection, Lot number: unknown; Expiration Date: unknown), dose 1 via an unspecified route of administration on 04Feb2021 15:45 as single dose for COVID-19 immunization. Medical history included learning disability (found out last March he has a genetic disability, MECP2, which is a gene that carries Rhett's, autism, and Asperger's), rectal hemorrhage, fecaloma. The patient previously took Lipitor and experienced blood creatine phosphokinase increased, Aricept (2 doses, 1 in am and 1 in pm) and experienced gait inability and rhabdomyolysis, simvastatin (20mg for years and that was discontinued back in Jan or Feb of 2020), atorvastatin and experienced rhabdomyolysis and coumadin and experienced atrial fibrillation. Concomitant medications was not reported. Around Apr or Mar of 2020, the patient was hospitalized, and his creatinine kinase level was about 6000 and got better and was diagnosed with rhabdomyolysis. The creatinine kinase level on 16Jun2020 was 131 and on 17Dec2020 his creatinine kinase total level was 56 and that the range is 44-196. After receiving the first dose of vaccine, the patient wasn't feeling well, he reportedly has at baseline of being unable to articulate how he feels due to depressed ability to speak, but "he began talking to himself, had nausea and wasn't feeling well". So they took him to the doctor and had labs drawn on 12Feb2021 which showed elevated creatinine kinase levels measuring 1,019. They were instructed to speak to a rheumatologist and got another level on 22Feb which came back as 66. The pharmacist reported that back in Dec2020, the patient's kinase level was 55.  Kinase was 1015 (blood creatine phosphokinase increased) on 12Feb2021, feeling unwell, nausea, unable to articulate how he feels due to depressed ability to speak, panic, anxiety in 2021. The pharmacist reported that he was told by the physician that it is possible the COVID vaccine is not safe. They were instructed to speak to a Rheumatologist and got another level on 22Feb which came back as 66. The patient's appointment is the same day as COVID vaccine, 28Feb2021. The patient is scheduled to receive his second dose of the vaccine this Thursday and he asked if it is safe to receive the second dose of the vaccine after reacting to the first. The patient underwent lab tests and procedures which included blood creatine phosphokinase: 6000 on 2020, 131 on 16Jun2020, 55 on Dec2020, 56 on 17Dec2020, 1015 on 12Feb2021, 1019 on 13Feb2021, 66 on 22Feb2021, magnetic resonance imaging: diagnosed with MECP2 on 12Feb2021, weight: 180-190 lbs, weight: 141-142 lbs, weight: 140.2 or 140.8 lbs on 12Feb2021. The reporter assessed the events to be non-serious. The outcome of the events was unknown.  Information about lot/Batch requested.