After / shot #1: She got a patch of shingles across her shoulder; After each vaccine patient had swelling / finger swelling; Blood pressure was raised / same effects after both / vaccine; Retained water / had to have a ring cut off / same effects after both / vaccine; Shingles are painful; Got a temperature (fever); Had diarrhea; Soreness in the joints; Aching down the leg / one of her feet / there was a "pocket" / causing excoriating pain; Back pain; Edema in her legs around the 3rd or 5th day; finger swelling; Coronavirus infection; This case was reported by a consumer via call center representative and described the occurrence of shingles in a 50-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included joint surgery (had soreness in the joints and had previous surgery), hip surgery, back surgery, plantar fasciitis, blood pressure high, memory disturbance (Family History) (patients mother was in a memory care center.) and hereditary disorder. Previously administered products included Steroid shot with an associated reaction of anxiety (received steroid shots in her feet on an unknown date, which caused anxiety for her).   In January 2021, the patient received the 1st dose of Shingrix. On an unknown date, less than 6 months after receiving Shingrix, the patient experienced shingles, swelling, increased blood pressure, water retention, pain, fever, diarrhea, joint pain, pain in extremity, back pain, leg edema, swelling of fingers and coronavirus infection. The patient was treated with levofloxacin (Levaquin). On an unknown date, the outcome of the shingles, swelling, increased blood pressure, water retention, pain, fever, diarrhea, joint pain, pain in extremity, back pain, leg edema and swelling of fingers were unknown and the outcome of the coronavirus infection was recovered/resolved.   It was unknown if the reporter considered the shingles, swelling, increased blood pressure, water retention, pain, fever, diarrhea, joint pain, pain in extremity, back pain, leg edema, swelling of fingers and coronavirus infection to be related to Shingrix.  Additional details were provided as follows: The case was reported by the consumer for herself. The age at vaccination was not reported. The patient reported that, after each vaccine she had swelling.  The patient received first dose of Shingrix vaccine and the blood pressure was raised which caused her to retained water and she had to have a ring cut off. The patient currently had shingles and did receive both the Shingrix shot, she would not provide the dates of the shots. She thought that might be she got Shingrix 1st shot in January 2021 but she was not sure. The patient said shingles were painful and she did not want to look up addresses (dates) right now but she would be willing to fill out consent form so that could contact her pharmacy and primary care doctor and urgent care to find out the dates of all the shots. The patient reported that, after Shingrix first shot she got a patch of shingles across her shoulder, got a temperature (fever), had diarrhea. She had soreness in the joints where she had previous surgery, aching down the leg where she had had previous hip surgery, back pain where she had previously had back surgery.  The patient said she had swelling from the beginning and she noticed edema in her legs around the 3rd or 5th day after the Shingrix first shot. The patient said that about 5 days after the Shingrix first shot she had to have a ring cut off of her finger even though it was an expanding ring that was made to expand in case your blood pressure goes up. this was after she had already raised her arm for 5 minutes and put ice packs on it to try to get the finger swelling to resolve. The patient diagnosed with Coronavirus and treated with Levaquin and was sick for 3 weeks. The patient received first dose of Covid  on 8thApril 2021, then received second dose of Covid  sometime before her foot operation around 29th April 2021.  The patient said she thought she had plantar fasciitis (pre-existing) and had been getting steroid shots in her feet, which caused anxiety for her. The patient said that one of her feet never got better and they took an X-ray of the foot and there was a pocket which was causing excoriating pain and the surgery was done where bone was taken off from the foot. she said the foot problem was due to a genetic hereditary deformity, she stated she was taking Levaquin at the time. The patient said she was scared to death because she had confusion. No further information was reported. For the tolerance of the second dose refer case US2021AMR161026.; Sender's Comments:  US-GLAXOSMITHKLINE-US2021AMR161026:Same reporter