Utterly fatigued; zonked out/Weak; aches/Pains; fever; shaking and shivering; shaking and shivering; She reported with the booster shot; She reported with the booster shot; out of it, fogged out, brain fog, like a really a cloudy sensorium; Nauseated; headache; Didn't want to eat; This is a spontaneous report received from a contactable consumer.  A 77-year-old female consumer(patient) reported that received booster of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; Lot number EW0191) in the left arm on 26Aug2021 at around 14:45 (at the age of 77-year-old ) as single dose for COVID-19 immunization. She had received the first dose of BNT162B2 on 09Feb2021 (Lot: EL9264, Expiry: 31May2021) and the second dose on 02Mar2021 (Lot: EN6199, Expiry: 30Jun2021). She was eligible for the booster shot because of being immunocompromised. She had no adverse reaction to the first dose. She reported adverse reactions with the second dose and booster shot. After receiving the second dose of vaccine she experienced Aches/Pains and Fatigue. Medical history included breast cancer  and osteoporosis.  Concomitant drugs included Anastrazole 1mg tablet taken daily for 3.5 years because after radiation oncologist started this to cut off estrogen because she had breast cancer, , Benazepril 20mg nightly for Blood pressure, Omeprazole 20mg capsule daily in the morning  since Jun2021 started after endoscopy performed couple months ago for spasm of a hiatal hernia and Warfarin  5mg tablet every day except monday; monday take 1.5 tablets because she has hereditary condition where she is predisposed to clots. She reported with the booster shot the adverse events she experienced was equivalent like going through a bad chemo treatment. Further described: At first started with aches and pains; this is like what it was before; then during the night she started to have a fever and by that time she was really zonked out; thought don't think it's a high fever, just tried to go back to sleep; woke up shaking and shivering, she had to put a wool blanket on over her down blanket and sheet. By morning the shakes and the fever had gone. Then she was just utterly fatigued; it felt like chemo because this is what she sometimes went through a couple of days after the chemo just before you go into the down cycle. She couldn't believe it, because one thing she never gets is nauseated; but she got nauseated with this and had a headache. She was out of it, fogged out, brain fog, like a really a cloudy sensorium. A friend of hers came to check on her to see if she was ok and patient didn't even know what day it was, she was just fogged out. It was really kind of dangerous for her to be alone. If she had known she would experience this kind of wipe-out she would have made sure a friend or nephew stayed with her or checked in to see that she was ok.  She didn't want to eat. She continued to have aches and pains and it was not good. The 3rd day she managed to get up and sit up a bit. The nausea continued; even when she had chemo she didn't have nausea; she does not get nauseated; this was kind of an odd sensation for her. She didn't feel up to doing anything and went back, spent half her time in bed during the day. 29Aug2021 she started to come around; got herself dressed, sat up for about maybe 6 hours but then she'd feel overcome by fatigue and would go take a nap and sleep for a while. It was very much like chemo with the added treats of a headache which she never gets.  At the time of reporitng she is pretty well back to normal, of course she is weak so she has to be careful walking around going up and down stairs stuff like that; but she is able to function.; Sender's Comments: Linked Report(s) :PFIZER INC-202101130917 same patient/vaccine, different dose /event