EYES BLOOD SHUT RED; FELT LIKE A HEART ATTACK; CHEST PALPITATION; ARM NUMBNESS; MINOR PANIC ATTACK; ANXIETY THAT IS AFFECTING HIS  DAILY FUNCTIONS LIKE DRIVING,  WALKING, TAKING A SHOWER; FLU-LIKE SYMPTOMS LIKE SWEATS AND CHILLS; SLEPT FOR 20 HOURS; PASSED OUT; BRAIN FOG; This spontaneous report received from a patient concerned a 52 year old male. The patient's height, and weight were not reported. The patient's concurrent conditions included: athletic induce asthma, alcohol user (very seldom every 6 months), and smoker (does not smoke but uses vapes and nicotine gum (2mg) sometimes), and other pre-existing medical conditions included: The patient had no known drug abuse or illicit drug usage. The patient experienced drug allergy when treated with influenza vaccine (20 years ago) for prophylactic vaccination, and drug allergy when treated with prednisone.  The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 1820095, and expiry: 02-OCT-2021) dose was not reported, 1 total administered on 28-JUL-2021 on left arm for prophylactic vaccination. Concomitant medications included nicotine for product use for unknown indication.  On 28-JUL-2021, immediately after vaccination the patient lied down passed out for 10 to 15 minutes. The patient went to dinner and did not remember how patient got there and was foggy. On 29-JUL-2021 (reported as a next day), the patient had flu-like symptoms like sweats, chills and slept for 20 hours. The next day patient was the same. On 30-JUL-2021 (reported as third day), patient felt great and back to normal. On an unspecified date in Aug-2021, patient had a minor panic attack and had anxiety when patient was driving. On 15-OCT-2021, patient was driving and felt like a heart attack, arm numbness and chest palpitation. On 16-OCT-2021, patient had eyes blood shut red and went to the hospital. The patient treated like a heart event and did all tests such as blood work, covid test, stress with echo, chest x-ray and they all came back normal with perfect cholesterol level. Then patient saw his PCP and treated it like anxiety and put him on 3-4 different medicines and they made it worse. The panic attacks went on an unspecified date in NOV-2021 and on 09-DEC-2021, patient did the MRI (Magnetic resonance imaging) of the brain and it showed the brain of 32 year old in white matter. Patient saw a neurologist and also on an unspecified date in JAN-2022 wore a heart monitor for 2 weeks. Patient said that his anxiety was so high that patient could not drive, anxiety getting into shower (patient was a neat person) and patient had anxiety going for a walk. Patient said that patient did not have any of these symptoms before getting the vaccine and how patient could take it out of his system. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from passed out on 28-JUL-2021, brain fog, flu-like symptoms like sweats and chills, and slept for 20 hours on 30-JUL-2021, and eyes blood shut red, felt like a heart attack, arm numbness, and chest palpitation, and had not recovered from minor panic attack, and anxiety that is affecting his daily functions like driving, walking, taking a shower. This report was serious (Other Medically Important Condition).; Sender's Comments: V0:20220130276-covid-19 vaccine ad26.cov2.s-Passed out .This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).