This was the 3rd shot; This was the 3rd shot; throwing up; diarrhea; blood sugar is high; headache; weakness; queasiness/Feeling queasy; she took her blood pressure and it was up; she felt sleepy like she did before; poop was dark in color; feels like crap; She has been sick all night long; This is a spontaneous report from a contactable consumer or other non-hcp (Patient). A 57-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: solution for injection; Lot Number: FA7485) via an unspecified route of administration (age at vaccination 57-year) on 16Sep2021 as dose 3 (booster), single for COVID-19 immunization. Medical history included high blood pressure, Stroke (4 strokes, 2012, 2016, 2018 after kidney transplant and then Dec2020), Diabetes (diagnosed about 3 years before she started dialysis), COVID-19 (she got COVID while in the hospital), all from an unknown date and unknown if ongoing; Heart attack from 2016 to an unknown date; Kidney transplant (was on dialysis for 7 years) from 24Sep2018 to an unknown date. Concomitant medications were unspecified. Historical vaccine included first dose of BNT162B2 (Lot Number: EN6204) administered on 09Mar2021, and second dose of BNT162B2 (Lot Number: ER7833) administered on 30Mar2021, for COVID-19 immunization; after both dose of vaccine administration the patient experienced sleepy and tired. On 16Sep2021 the patient experienced throwing up, diarrhea, blood sugar was high, headache, weakness, queasiness/feeling queasy, she took her blood pressure, and it was up; on an unspecified date in 2021 the patient experienced she had been sick all night long, feels like crap, she felt sleepy like she did before, poop was dark in color. The patient underwent lab tests and procedures which included blood glucose: 144 (increased) on 17Sep2021, blood pressure measurement: it was up on 16Sep2021. Therapeutic measures were taken as a result of, blood sugar was high, she took her blood pressure, and it was up. It was reported that "Caller got her 3rd Pfizer shot yesterday as she had kidney transplant, heart attack,4 strokes and is diabetic. She had been sick all night long, throwing up, diarrhea, feels like crap, blood sugar is high, headache, weakness and queasiness. Caller asking if the 1st dose and the second dose is the same with the 3rd dose. Stated she did not had covid and stays in their house, wears mask and gloves. Prior to getting the 3rd COVID shot yesterday, she felt good. When the caller got home from getting the 3rd COVID shot, she stated that she felt sleepy like she did before; clarified as all of the other COVID shots mad her tired and sleepy. She slept in the chair until 6 o'clock last night. She went upstairs about 9 o'clock and by 11 or 12 o'clock, she was sick as a dog. Caller stated that she felt like she was going to fall out. She stayed in the bathroom last night for about 2 to 3 hours with a garbage can in front of her throwing up, while sitting on the toilet pooping. The poop started as regular poop and then it would not stop. So, she sat there. The poop turned to diarrhea. The poop was dark in color. After sitting on the toilet for 2 to 3 hours, she had to go back to the bathroom again. Today caller feels like crap because she was up all night on the toilet pooping and throwing up. It was horrible. Caller was weak and had a headache. Her blood sugar was high. Stated that she takes her blood pressure 3 times a day. Last night (16Sep2021), she took her blood pressure, and it was up after she had already taken her regular blood pressure medicine. So, she took 25mg of hydralazine to bring her blood pressure down,25mg of hydralazine was what she takes to bring her blood pressure down, short term. She takes her regular blood pressure medicine twice a day. Caller stated that her blood sugar was high when she went to bed last night and she had a to take an unspecified shot last night. This morning,17Sep2021, when she got up, her blood sugar was 144 which was high for her. She watches her blood sugar very closely and with all that throwing up, her blood sugar should not had been this high, this morning. Caller wants to know how she can feel better. Caller repeated multiple times that she feels like crap today. She had not thrown up this morning but feels queasy and weak. She was scared to eat because when she tries to eat, she feels like she was going to throw up again. She had not thrown up since during the night. She had not had any diarrhea since she got up today. Caller had not notified her doctor yet but stated that she will call the doctor after she speaks to someone in medical information. History: Caller stated that she was in the hospital in Dec2021 after having a stroke. She got COVID while in the hospital. Stated that after she came home from the hospital from having the stroke, she had to go back to the hospital the next morning because she had the COVID virus. Stated that she after having the 3rd COVID shot, she feels just like she did when she had the COVID virus. In March 2021, she had the first and second doses of the COVID shot. Dose 1 was 09Mar2021 and dose 2 was 30Mar2021. Caller stated that she was not sure if she really needed the 3rd COVID shot or not, injecting a live virus in her. Caller declined to provide her medications, stating that she takes so much medication-2 bags full." The clinical outcome of the events "blood sugar was high, headache, weakness, queasiness/feeling queasy" was not resolved, while the outcome of other events was unknown.   Follow-up attempts are completed. No further information is expected.