After having a PSA score of 4.8 ( normal) Psa Jumped to 7.1 after shot.; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 69-year-old male patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 12Sep2022 at 12:00 as dose 5 (booster), single (Lot number: 6H9694) at the age of 69 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Coronary artery disease" (unspecified if ongoing); "Prinzmetal angina" (unspecified if ongoing); "Known allergies: Penicillin" (unspecified if ongoing). The patient's concomitant medications were not reported. Past drug history included: Codeine, reaction(s): "Known allergies: Codeine". Vaccination history included: coviD-19 vaccine (Prev dose product = COVID 19 , Prev dose brand = Booster, Prev dose brand unknown = False, Is bivalent = False, Prev dose lot number = FJ4991, Prev dose lot unknown = False , Prev dose administration date = 16Jun2022, Prev dose administration time = 01:00 PM, Prev dose dose number = 4, Prev dose vaccine location = Left arm), administration date: 16Jun2022, when the patient was 69-year-old, for COVID-19 immunization; BNT162b2 (Prev dose product = COVID 19 , Prev dose brand = Pfizer, Prev dose brand unknown = False, Is bivalent = False, Prev dose lot number = fe3592, Prev dose lot unknown = False , Prev dose administration date = 09Sep2021, Prev dose administration time = 12:00 PM, Prev dose dose number = 3, Prev dose vaccine location = Left arm), administration date: 09Sep2021, when the patient was 68-year-old, for COVID-19 immunization; BNT162b2 (Prev dose product = COVID 19 , Prev dose brand = Pfizer, Prev dose brand unknown = False, Is bivalent = False, Prev dose lot number = en6208, Prev dose lot unknown = False , Prev dose administration date = 17Mar2021, Prev dose administration time = 12:00 PM, Prev dose dose number = 2, Prev dose vaccine location = Left arm), administration date: 17Mar2021, when the patient was 68-year-old, for COVID-19 immunization; BNT162b2 (Prev dose product = COVID 19 , Prev dose brand = Pfizer, Prev dose brand unknown = False, Is bivalent = False, Prev dose lot number = EN6288, Prev dose lot unknown = False , Prev dose administration date = 02Jan2021, Prev dose administration time = 12:00 PM, Prev dose dose number = 1, Prev dose vaccine location = Left arm), administration date: 02Jan2021, when the patient was 68-year-old, for COVID-19 immunization.  The following information was reported: PROSTATIC SPECIFIC ANTIGEN INCREASED (medically significant) with onset 12Oct2022 at 12:00, outcome "unknown", described as "After having a PSA score of 4.8 ( normal) Psa Jumped to 7.1 after shot." The event "after having a psa score of 4.8 ( normal) psa jumped to 7.1 after shot." required physician office visit. The patient underwent the following laboratory tests and procedures: Prostatic specific antigen: (unspecified date) 4.8, notes: PSA score of 4.8 (normal); (12Oct2022) 7.1, notes: PSA jumped to 7.1 after shot. Therapeutic measures were not taken as a result of prostatic specific antigen increased.  Follow-up attempts are completed. No further information is expected.