Ankles and knees swollen; Knees are stiff; I can't walk, well just a little bit (Needs to use a wheelchair now); Things don't register; I don't know if you call it brain fog because I don't know what that is; Developed a new trigger point in the upper right shoulder blade; Sense of taste is off; Nothing taste good; Gained 17 pounds since the first vaccine; Headache; This spontaneous case was reported by a patient and describes the occurrence of JOINT SWELLING (Ankles and knees swollen), JOINT STIFFNESS (Knees are stiff), GAIT DISTURBANCE (I can't walk, well just a little bit (Needs to use a wheelchair now)), MEMORY IMPAIRMENT (Things don't register) and FEELING ABNORMAL (I don't know if you call it brain fog because I don't know what that is) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 002C21A and 010M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Back surgery in August 2020. Concurrent medical conditions included Blood pressure abnormal and Diabetic. Concomitant products included INSULIN ASPART (NOVOLOG), GABAPENTIN, ATENOLOL, HYDROCHLOROTHIAZIDE, TRIAMTERENE (MAXZIDE), ENALAPRIL, ALLOPURINOL, DULAGLUTIDE (TRULICITY), PROMAZINE, VACCINIUM MACROCARPON (CRANBERRY EXTRACT [VACCINIUM MACROCARPON]), MULTIVITAMINS [VITAMINS NOS], GLUCOSAMINE, CHONDROITIN, ASTAXANTHIN, ACETYLSALICYLIC ACID (ASPIRIN LOW), PROBIOTICS NOS, COLECALCIFEROL (VITAMIN D3), MAGNESIUM and FEXOFENADINE HYDROCHLORIDE (FEXOFENADINE HCL) for an unknown indication.   On 31-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 28-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 06-Apr-2021, the patient experienced JOINT SWELLING (Ankles and knees swollen). In April 2021, the patient experienced JOINT STIFFNESS (Knees are stiff), GAIT DISTURBANCE (I can't walk, well just a little bit (Needs to use a wheelchair now)), MEMORY IMPAIRMENT (Things don't register), FEELING ABNORMAL (I don't know if you call it brain fog because I don't know what that is), PAIN (Developed a new trigger point in the upper right shoulder blade), AGEUSIA (Sense of taste is off), TASTE DISORDER (Nothing taste good), WEIGHT INCREASED (Gained 17 pounds since the first vaccine) and HEADACHE (Headache). The patient was treated with Manual therapy for Memory impairment; Manual therapy for Feeling abnormal; Manual therapy for Pain; Manual therapy for Ageusia; Manual therapy for Taste disorder; Manual therapy for Weight increased and Manual therapy for Headache. At the time of the report, JOINT SWELLING (Ankles and knees swollen), JOINT STIFFNESS (Knees are stiff), GAIT DISTURBANCE (I can't walk, well just a little bit (Needs to use a wheelchair now)), MEMORY IMPAIRMENT (Things don't register), FEELING ABNORMAL (I don't know if you call it brain fog because I don't know what that is), PAIN (Developed a new trigger point in the upper right shoulder blade), AGEUSIA (Sense of taste is off), TASTE DISORDER (Nothing taste good), WEIGHT INCREASED (Gained 17 pounds since the first vaccine) and HEADACHE (Headache) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In April 2021, Blood glucose: abnormal (abnormal) blood sugar level is all out of the place/blood sugar was 149 and fell down to 88 within 2-hours after eating (Blood glucose fluctuation).. In April 2021, Blood pressure measurement: 145/90 (High) +20 point change in blood pressure level, which has risen to 145/90.. On 16-Jun-2021, Blood glucose: abnormal (abnormal) blood sugar was 149 and fell down to 88 within 2-hours after eating today.         Patient stated that she went to an Acupuncturist/Message therapist for the right shoulder trigger point, she experienced relief for one day; she continues therapy for this.   This case was linked to MOD-2021-224276 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 16-Jun-2021: Additional information received: Updated Lab data