2nd dose administered in the cavity between the bone and the muscle; itchy scalp; brain fog; lost her eye sight, she couldn't see; arm  had limited range of motion/arm felt stiff; exhausted/ weak; low grade fever but didn't have a thermometer/ Out of sorts; joint pain; headache; Nauseated; Extreme pain on the right side of her body from her shoulder to the top of her head/muscle ache/body ache; This spontaneous case was reported by a consumer and describes the occurrence of BLINDNESS (lost her eye sight, she couldn't see) in an 80-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 019B21A, 010A21A and 067F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Cancer (Cancer 3 times), Kidney stones and Intestinal inflammation (that needed surgery). Concurrent medical conditions included Sulfonamide allergy (and something else she doesn't remember.) and Muscle mass (lacks muscle in her arm.).   On 26-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 22-Apr-2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 26-Mar-2021, the patient experienced LIMB DISCOMFORT (arm  had limited range of motion/arm felt stiff), PYREXIA (low grade fever but didn't have a thermometer/ Out of sorts), ARTHRALGIA (joint pain) and HEADACHE (headache). 26-Mar-2021, the patient experienced FATIGUE (exhausted/ weak), NAUSEA (Nauseated) and MYALGIA (Extreme pain on the right side of her body from her shoulder to the top of her head/muscle ache/body ache). On 28-Mar-2021, the patient experienced BLINDNESS (lost her eye sight, she couldn't see) (seriousness criterion medically significant). On an unknown date, the patient experienced WRONG TECHNIQUE IN PRODUCT USAGE PROCESS (2nd dose administered in the cavity between the bone and the muscle), PRURITUS (itchy scalp) and FEELING ABNORMAL (brain fog). At the time of the report, BLINDNESS (lost her eye sight, she couldn't see) had resolved with sequelae, LIMB DISCOMFORT (arm  had limited range of motion/arm felt stiff), PRURITUS (itchy scalp), FEELING ABNORMAL (brain fog), FATIGUE (exhausted/ weak), PYREXIA (low grade fever but didn't have a thermometer/ Out of sorts), ARTHRALGIA (joint pain), HEADACHE (headache), NAUSEA (Nauseated) and MYALGIA (Extreme pain on the right side of her body from her shoulder to the top of her head/muscle ache/body ache) was resolving and WRONG TECHNIQUE IN PRODUCT USAGE PROCESS (2nd dose administered in the cavity between the bone and the muscle) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Treatment information was not provided.No concomitant medication details were provided.Patient received her first dose of the Moderna COVID-19 vaccine on 26Feb2021 and she experienced the following only for the day: pain and soreness at the injection site, extremely hungry and a headache.On 26Mar2021 she received her second dose and immediately after they injected the vaccine she experienced the following up to 04May2021 (the symptoms started diminishing on 30Mar2021 though): Extreme pain on the right side of her body from her shoulder to the top of her head, she waited 30 minutes and when she got home she was extremely hungry, exhausted, nauseated, weak, out of sorts, thirsty but only could tolerate a couple of sips of water without feeling like throwing up, shooting pains, arm felt stiff and had limited range of motion, low grade fever but didn't have a thermometer, headache, joint pain, muscle ache, body ache, itchy scalp, brain fog, emotional outburst of negativity, tears. Specifically on 28Mar2021, she lost her eye sight, shecouldn't see. She still has some Company comment-This spontaneous case concerns a 80-year old, female patient with no relevant medical history reported, who experienced the unexpected serious (medically significant) event of Blindness and multiple non-serious events after receiving second dose of mRNA-1273 vaccine. Patient experienced severe fatigue, pain on right side of her body, headache, nausea, low grade fever, muscle and joint pain, itchy scalp with a feeling of abnormal on the same day of vaccination. She also reported Wrong injection technique. Two days later she lost her eye sight and couldn't see. Consulted with Primary Care Doctor and Ophthalmologist. Details not reported. She still has some residual effects. Patient had received 1st dose of Moderna 28 days prior to second dose. Elderly age of the patient remains a confounder to the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-552364 (Patient Link).; Sender's Comments: This spontaneous case concerns a 80-year old, female patient with no relevant medical history reported, who experienced the unexpected serious (medically significant) event of Blindness and multiple nonserious events after receiving second dose of mRNA-1273 vaccine. Patient experienced severe fatigue, pain on right side of her body, headache, nausea, low grade fever, muscle and joint pain, itchy scalp with a feeling of abnormal on the same day of vaccination. She also reported Wrong injection technique. Two days later she lost her eye sight and couldn't see. Consulted with Primary Care Doctor and Ophthalmologist. Details not reported. She still has some residual effects. Patient had received 1st dose of Moderna 28 days prior to second dose. Elderly age of the patient remains a confounder to the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.