BODY ACHES; EXTREME ANXIETY; BLURRED VISION; REACTIVE LYMPH NODE; LEFT AND RIGHT SORE ARMPIT; LEFT ARM SWELLED UP; INJECTION SITE SWELLED UP (RIGHT ARM); TENDERNESS AT THE INJECTION SITE; HIVES (LOOKED LIKE MOSQUITO BITES IN THE LEFT ARM AND UPPER ARM)/ITCHY/SCABBED OVER; This spontaneous report received from a patient concerned a 75 year old female. Initial information was processed along with additional information received on 24-DEC-2021. The patient's height, and weight were not reported. The patient's past medical history included: covid-19, and concurrent conditions included: prothrombin issue, non alcohol user, non smoker, body aches antibiotics allergy (body aches, malaise, fatigue, flulike symptoms, and other pre-existing medical conditions included: The patient had no drug abuse or illicit drug usage. The patient sister had history of breast cancer and her daughter has factor V issue. The patient previously received covid-19 vaccine ad26. cov2. s (Janssen, Dose number in series 1) (suspension for injection, route of admin not reported, batch number were not reported) dose was not reported, 1 total, administered on 07-APR-2021 for prophylactic vaccination. No adverse events where reported. (Dose number in series 1) The patient received covid-19 vaccine ad26.cov2.s (Janssen, Dose number in series 2) (suspension for injection, route of admin not reported, batch number: 211D21A, expiry: 11-APR-2022) dose was not reported, 1 total, administered on 17-NOV-2021 to Right Arm for prophylactic vaccination. No concomitant medications were reported.  On 21-NOV-2021, Post booster dose about 4 to 5 days the patient developed hives which looked like mosquito bites in the left arm and upper arm (4-5 bites) that were very itchy and then scabbed over. she also mentioned she lived in Florida and that could had been possible that it was by mosquito bites and then her right arm (where injection was done) swelled up and the left arm also swelled up 2-3 days after around 22-NOV-2021 and also the location of the injection is still tender and she felt the shot as it went in. On 24-NOV-2021, around the patient went to urgent care, as patient was worried about blood clot (she has prothrombin issue. The patient did ultrasound and told her that there was no blood clot. After ultrasound was done it was found that patient had a reactive lymph node on the left side, her left armpit has been sore and now the right one is sore a bit. Patient is also suffering from blurred vision which thinks is because of the video games she plays on her phone. The patient had body aches when she wakes up but says she had them before vaccination as well. The patient is quite worried and says that she had anxiety in the past about blood clot and has taken alprazolam for it. The Patient also mentioned she suffers from extreme anxiety and it is possible for her to experience all of the symptoms associated with blood clots if she is extremely anxious. The patient stated that her doctor informed her that the reactive lymph node detected by ultrasound on her left arm was a sign her he had them before vaccination as well. (Dose number in series 2) The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from left arm swelled up, hives (looked like mosquito bites in the left arm and upper arm)/itchy/scabbed over, and injection site swelled up (right arm), had not recovered from tenderness at the injection site, reactive lymph node, and left and right sore armpit, and the outcome of body aches, extreme anxiety and blurred vision was not reported. This report was non-serious. This case, from the same reporter is linked to 20211255466.