This is a spontaneous report from a contactable consumer (patient). A 42-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection), via an unspecified route of administration, administered in the left arm on 29Apr2021 at 12:15 PM (Batch/Lot Number: EW0175) at the age of 42-years-old as 2nd dose, single for COVID-19 immunization at a pharmacy/drug store. The patient had no other vaccines administered on the same date as BNT162B2. The patient had no prior vaccinations (within 4 weeks). The patient's medical history included depression from an unknown date and unknown if ongoing. Concomitant medications included a medication (unspecified) for depression. The patient previously received the first dose of BNT162B2 at the left arm on 07Apr2021 at 12:15 PM (Lot Number: EW0153) at the age of 42-years-old for COVID-19 immunization and experienced headaches, episodes of dizziness, and weakness. On 29Apr2021, the patient experienced extreme headache like her head was going to explode, chest palpitations, nauseous, sick, dizziness, vomiting, and pressure in her chest. It was reported that during the evening after having her second dose on 29Apr2021 she experienced "extreme headache, dizziness and vomiting" as well as pressure in her chest. The patient reported that she has been experiencing some side effects. She has an extreme headache like her head was going to explode. She was nauseous and she also felt like chest palpitations. She can't lay down her head because the headache starts immediately. She was asking if there was a plan for people with these problems, these side effects. She has been sick for five days and has been to the emergency room twice. With the first Covid 19 vaccine she experienced a little headache, dizziness, and weakness. She didn't think her side effects were from the vaccine. When she got the second Covid 19 vaccine, she had a headache and she knew it was definitely the vaccine. Now her symptoms were a hundred times stronger. When she received her second Covid 19 vaccine she was still experiencing side effects from the first Covid 19 vaccine. Her headache, it was like her head was going to explode. She was still having dizziness with the second Covid 19 vaccine. She went to the emergency department on Friday morning, 30Apr2021 and she was there the whole day. She received a migraine medicine and an allergy medicine in the emergency department. On Saturday night, 01May2021, she went back to the emergency department and she had a CAT scan, EKG, blood work and couldn't find anything wrong. She received migraine medication in the emergency department again on Saturday, 01May2021. It was terrible when she gets the headache, like it was going to explode. She's going to call her doctor and ask for something for pain. She was only prescribed Metoclopramide for nausea from the emergency department. She needs pain medicine to handle the pain when she gets the headache episode. She's having headache episodes in the daytime and nighttime. When probing indication for receiving the Covid 19 vaccine she reported she thought getting the vaccine was what she was supposed to do. If she knew she would have been this sick, she would have never gotten this Covid 19 vaccine, ever (as reported). The events required a visit to emergency room. The outcome of the events extreme headache, nauseous, and dizziness was not recovered. The outcome of chest palpitations, sick, vomiting, and pressure in her chest was unknown.