they mention the texture of their hair is different, it feels thinner and dryer; extreme fatigue; Around July2021 they noticed a lot of hair loss, their hair was falling out more than normal/ hair loss (diverse); This spontaneous case was reported by a consumer and describes the occurrence of ALOPECIA (Around July2021 they noticed a lot of hair loss, their hair was falling out more than normal/ hair loss (diverse)), HAIR TEXTURE ABNORMAL (they mention the texture of their hair is different, it feels thinner and dryer) and FATIGUE (extreme fatigue) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 002A21A and 012M20A) for COVID-19 vaccination.     No medical history was provided by the reporter.  The patient's past medical history included AFib (no afib in more than a year) in June 2019. Previously administered products included for Product used for unknown indication: Shingrix from 10-Nov-2020 to 03-May-2021; for Pneumonia: Previnar (2nd shot) on 09-Dec-2020. Past adverse reactions to the above products included No adverse event with Previnar and Shingrix. Concurrent medical conditions included Penicillin allergy, Sulfonamide allergy, Allergy to antibiotic (Azithromycin), Drug allergy (Prednisone), Allergy to animal (Cat), Dust allergy, Sjoegren's syndrome (extreme fatigue) since November 2011, Brugada syndrome (extreme fatigue) since November 2009, Osteoarthritis since November 2011, Hypertension since January 2008, Hypothyroidism and High cholesterol. Concomitant products included ROSUVASTATIN CALCIUM (CRESTOR) from 01-May-2021 to an unknown date for High cholesterol, OLMESARTAN MEDOXOMIL (BENICAR) from 2017 to an unknown date for Hypertension, LEVOTHYROXINE SODIUM (SYNTHROID) from 1990 to an unknown date for Hypothyroidism, HYDROXYCHLOROQUINE SULFATE (PLAQUENIL [HYDROXYCHLOROQUINE SULFATE]) from 2011 to an unknown date for Sjoegren's syndrome, FLUCONAZOLE (FLUCONAL), CICLOSPORIN (RESTASIS) and ALUMINIUM HYDROXIDE GEL, DRIED, MAGNESIUM CARBONATE (PEPCID [ALUMINIUM HYDROXIDE GEL, DRIED;MAGNESIUM CARBONATE]) for an unknown indication.   On 29-Jan-2021 at 1:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Feb-2021 at 2:40 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 01-Jul-2021, the patient experienced ALOPECIA (Around July2021 they noticed a lot of hair loss, their hair was falling out more than normal/ hair loss (diverse)) and FATIGUE (extreme fatigue). On an unknown date, the patient experienced HAIR TEXTURE ABNORMAL (they mention the texture of their hair is different, it feels thinner and dryer). At the time of the report, ALOPECIA (Around July2021 they noticed a lot of hair loss, their hair was falling out more than normal/ hair loss (diverse)), HAIR TEXTURE ABNORMAL (they mention the texture of their hair is different, it feels thinner and dryer) and FATIGUE (extreme fatigue) had not resolved.            Acute illnesses at the time of vaccination and up to one month before was reported as none. About 5 months later after vaccination, the patient noticed that she was losing more hair than normal. When she washed her hair, lots of hair was on her hands. The hair loss was diverse (no bald spots). The only time that ever happened was 30plus years ago, when she was diagnosed with hypothyroidism. She mentioned the hair loss to her PCP in mid-July along with extreme fatigue, and was seeing for a cosmetic treatment. The dermatologist examined and said that the hair loss should subside in about 3 months that would be by the end of September. She noticed slowing of the hair loss but her usual full head of healthy hair was thin, limp and very dry. The PCP ran a battery of tests, and did not had an explanation.  In the past the patient had these condition years ago, low thyroid and after surgery/anesthesia and sjogrens, hypothyroid.  The patient had flu shot on 29-Sep-2021. The also had supplements as other concomitant medication.   This case was linked to MOD-2021-358708 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 21-Oct-2021: Follow up received on 21-OCT-2021  Updated Patient (added medical history, race, ethnic origin), Products (added indication, start date of concomitant medication), Event (updated outcome of the events, onset date) and narrative.