This spontaneous report was received from a patient's mother and refers to a 17 year old male patient. The patient's medical history, drug reaction and concurrent conditions were not reported. On 08-MAR-2017, the patient was vaccinated with a first and only dose of GARDASIL 9 0.5 ml, injected in his right arm in the upper quadrant (route of administration, lot number and expiration date were not reported), for human papillomavirus (HPV) prevention. Concomitant vaccine included unspecified meningitis vaccine. On the same day (reported as "immediately after getting the first dose"), the patient started to experience aches and pains in his arms and shoulders. On an unknown day approximately in March 2017 (reported as "since being vaccinated"), the patient started to experience anxiety. On an unknown day in 2017 (reported as "a couple of weeks later"), he started experiencing frequent headaches and he developed neck pressure and vomiting every 3 to 4 days, which had persisted to the present time. At the time of the report, he could not move his upper shoulders or neck or otherwise he vomited. On an unknown day in 2017 (reported as"through-out the last year"), the patient's white blood count was not normal, reported as "it went up and down". The patient was taken out of the school he was attending (from 15-APR-2018) and he would not graduate on time, due to adverse event symptoms (reported as "he was sitting at home in a recliner with a puke bucket just vomiting"). Due to frequent vomiting he had "15 to 20" emergency room visits to get re-hydrated. The patient was hospitalized on an unknown date, due to frequent headaches, neck pressure and vomiting, dehydratation and white blood count abnormal for a approximately 2 days "the first couple of times" that he had gone to the Emergency Room where they performed unspecified magnetic resonance imaging (MRI), unspecified laboratory test and scans during his hospitalization. On the other ER visits (after the first couple visits to the ER) he was released the same day. On an unknown day in May 2018 (reported as "last May"), the patient had unspecified endoscopy performed and was diagnosed with being allergic to lactose (at the time of the report he was on a lactose free diet and he could not drink any milk or dairy-based products). He was scheduled to have another endoscopy done next month. On an unknown day, the patient was also diagnosed with dysautonomia. The patient had seen total of 20 in-patient and out-patient doctors (from gastroenterologist (GI) to neurologist) since getting the GARDASIL 9, but no doctor seems to know why he was experiencing all off these various symptoms. On an unknown day around April 2018, the patient visited neurologist, who though his symptoms might-be related to high levels of metals in his body like aluminum or mercury, which she felt might had been caused by the GARDASIL 9. At the time of the report, the patient was on "second round of detox" to try to remove these heavy metals from his body. He was also prescribed ondansetron hydrochloride (ZOFRAN), 10 mg for vomiting, but it was no longer effective and he tried over-the-counter medications like ibuprofen (ADVIL), acetaminophen (TYLENOL), bismuth subsalicylate (PEPTO-BISMOL) for vomiting and stomach problems started on an unknown date. The outcome of the events was reported as not recovered. The relatedness between the events and GARDASIL 9 was not reported. Upon internal review, vomiting was considered to be a cause of the patient's disability. This is one of two reports received from the same reporter.; Sender's Comments: US-009507513-1807USA007181: