Second Dose: swells up so bad in her legs and hands and the inflammation and pain is so bad, she has to call out of work; Second Dose: everything hurt, she couldn''t brush her teeth, put on her socks or touch her skin; Second Dose: pain in her breasts is phenomenal; Second Dose: everything to do with menstrual has totally changed 10 times worse, the last period, she threw up and she has never felt that bad; Second Dose: thinking she was having an aneurysm, it was the worst head pain in her life; Second Dose: period comes right on time, but it used to be 3-4 days, now it lasts 7 days, and causes excruciating pain on almost every one of those days; This is a spontaneous report received from a contactable reporter(s) (Other HCP).  A 42 year-old female patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. Relevant medical history included: "Fibromyalgia" (ongoing), notes: Since 5-6 Year of Age; "Urticaria" (ongoing), notes: Since 5-6 Year of Age; "Raynaud's phenomenon" (ongoing), notes: Verbatim: Raynaud''s disease. There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose 1, Dosage text: Left Arm both nurses so use right hand but can't be definitive.), for COVID-19 Immunization, reaction(s): "First Dose: dizzy".  The following information was reported: SWELLING (non-serious), outcome "unknown", described as "Second Dose: swells up so bad in her legs and hands and the inflammation and pain is so bad, she has to call out of work"; PAIN (non-serious), outcome "unknown", described as "Second Dose: everything hurt, she couldn''t brush her teeth, put on her socks or touch her skin"; BREAST PAIN (non-serious), outcome "unknown", described as "Second Dose: pain in her breasts is phenomenal"; MENSTRUAL DISORDER (non-serious), outcome "unknown", described as "Second Dose: everything to do with menstrual has totally changed 10 times worse, the last period, she threw up and she has never felt that bad"; HEADACHE (non-serious), outcome "unknown", described as "Second Dose: thinking she was having an aneurysm, it was the worst head pain in her life"; DYSMENORRHOEA (non-serious), outcome "unknown", described as "Second Dose: period comes right on time, but it used to be 3-4 days, now it lasts 7 days, and causes excruciating pain on almost every one of those days". Therapeutic measures were taken as a result of swelling, pain, breast pain, menstrual disorder, headache, dysmenorrhoea.  Additional information: It was reported that after second dose, patient felt a little crappy; hit her like a ton of bricks and got her period the day of the second dose. family medical history relevant to AE(s) included: caller states she has a Twin Sister that had all of the exact same reactions as her. Caller states they are not identical twins. Weight reported as 145-150. PCP: Unknown, she thinks she is in between right now. No other products reported and no investigation assessment. She reported that she was unknown of first and second doses and stated her sister got her vaccines later. Caller stated the dates of the adverse events are unknown, but they were like hers, dizzy with the first and then right after second one, it hit her like a ton of bricks with the side adverse effects are the exact same as she had. Treatment included: Motrin and Tylenol and stayed home. She stated her sister got her vaccine at her Place of work, (withheld).    No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.