Supraclavicular lymph nodes enlarged; mediastinal lymph node swelling; Hilar lymph node swelling; hot uh night sweats, like drenching night sweats; chest congestions; dry cough; his heart rate has been like at 100 to 120 and his breathing has been like 30 to 40 breaths per minute which is very abnormal for him; his heart rate has been like at 100 to 120 and his breathing has been like 30 to 40 breaths per minute which is very abnormal for him; WBC which is slightly elevated at the left shift; This is a spontaneous report from a contactable nurse (the patient's wife). A 31-years-old male patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot number was not reported), via an unspecified route of administration, administered in left arm on 22May2021 as a single dose for COVID-19 immunisation. The patient's medical history and concomitant medications were not reported. The patient previously received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Batch/Lot number was not reported), via an unspecified route of administration, on 01May2021 as a single dose for COVID-19 immunisation. On 29May2021, the patient experienced supraclavicular lymph nodes enlarged. On an unspecified date in 2021, he experienced mediastinal lymph node swelling, hilar lymph node swelling, hot uh night sweats, like drenching night sweats, chest congestions, dry cough, his heart rate has been like at 100 to 120 and his breathing has been like 30 to 40 breaths per minute which is very abnormal for him, WBC which is slightly elevated at the left shift. The reported stated that her husband got his 1st dose on 01May2021, 2nd dose on 22May2021 and 7 days after he developed super clavicular lymph node swelling on the same side of the injection site. It was on the left arm and he also developed hot uh night sweats, like drenching night sweats, and what he described as chest congestions but not like a cold. He described it as having a clear something in the center of his chest with no health symptoms at all. They waited 7 weeks thinking it was a cold on top of The Pfizer vaccine. He like has a dry cough. His heart rate has been like at 100 to 120 and his breathing has been like 30 to 40 breaths per minute which is very abnormal for him. He was a very athletic guy and his heart rate was usually in the 60, thats 60 at most. They went to urgent care first and her husband did a Chest XRAY and his labs. His platelets were on the 600, WBC which is slightly elevated at the left shift and was sent to the ER. When they were in the ER, they did a CT-Scan from neck to pelvis and they found he has mediastinal and hilar lymph nodes swelling as well as the super clavicular lymph nodes, 2 of there and the mediastinal and hilar lymph nodes swelling. ER don't know why and it was also on the left as well. The reported stated that she has studies online that say that can happen if the vaccine is given too high. The patient's wife was more concerned about it because of where the lymph node swelling was. She knows axillary has been reported. The patient was in the middle of a work-up for it now. The Reporter wanted to know there was been reports of ancillary lymph node swelling online. Her husband is not experiencing this one, she just read this online that other people were having it. She wanted to know if there was any report regarding mediastinal or hilar lymph node swelling and just wanted to know if other people are experiencing this side effect. Reporter also asked if we are now done studying and there was no follow up. Those were the clinical trials before and they vaccinated thousands of people and they does not seem to be like getting more information. Response: Informed her that the clinical trials was still ongoing and some of the reports were still not updated. On an unspecified date in 2021, the patient underwent lab tests and procedures which included Chest X-ray: unknown, CT-Scan: lymph nodes swelling (mediastinal and hilar lymph nodes swelling as well as the super clavicular lymph nodes), heart rate: 100 to 120, platelet: 600, breath rate: 30 to 40 (his breathing has been like 30 to 40 breaths per minute which is very abnormal for him), WBC: slightly elevated. The outcome of events was unknown.  Information on Lot/Batch number has been requested.