Reporting covid rebound, By today, 03-Jun, my rapid tests were solidly positive once again; This spontaneous case was reported by a patient and describes the occurrence of COVID-19 (Reporting covid rebound, By today, 03-Jun, my rapid tests were solidly positive once again) in a 37-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 033F21A) for COVID-19 vaccination.    Co-suspect product included non-company product NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment.    Relevant past drug history reported as, name of drug : no and reaction reported as Allergy.  Previously administered products included for Product used for unknown indication: Pfizer/Biontech (Dose number: 1, Batch/lot No: EWO151, Location of injection: Arm left) on 08-Apr-2021, Pfizer/Biontech (Dose number: 2, Batch/Lot No: EW0171 and Location of injection: Arm left) on 29-Apr-2021. Past adverse reactions to the above products included No adverse event with Pfizer/Biontech and Pfizer/Biontech.   On 01-Nov-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-May-2022, the patient started NIRMATRELVIR, RITONAVIR (PAXLOVID) (unknown route) at an unspecified dose. On 03-Jun-2022,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced COVID-19 (Reporting covid rebound, By today, 03-Jun, my rapid tests were solidly positive once again). At the time of the report, COVID-19 (Reporting covid rebound, By today, 03-Jun, my rapid tests were solidly positive once again) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 31-May-2022, SARS-CoV-2 test: negative (Negative) Negative. On 03-Jun-2022, SARS-CoV-2 test: positive (Positive) Positive.         Reported that the patient was not taking any other medications/products within 2 weeks of starting COVID- 19 treatment.  No concomitant medication information provided. Reported that covid rebound, patient took Paxlovid and was thrilled to test negative for Covid on May 31 on two different rapid tests, after patient finished course of Paxlovid. Over the next few days patient went between testing negative and having a faint positive line on rapid tests. Assumed it was clearing the system. By today, 3-Jun, rapid tests were solidly positive once again. Device Date 03-Jun-2022. Company comment: This spontaneous case concerns a 37-year-old female patient with no relevant medical history reported, who experienced the unexpected non-serious AESI event of COVID-19, which occured 7 months after receiving third dose of mRNA-1273 vaccine. It was reported that patient was treated with Paxlovid from 26-may-2022 to 30-may-202. She was tested positive 2 days after the treatment with Paxlovid. Patient had received 2 doses of Comirnaty COVID-19 vaccine approximately 6 3 months prior to mRNA-1273 vaccination (Interchange of vaccine products). The current pandemic situation of COVID 19 may remain as confounder to the event Covid-19.  The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 37-year-old female patient with no relevant medical history reported, who experienced the unexpected non-serious AESI event of COVID-19, which occured 7 months after receiving third dose of mRNA-1273 vaccine. It was reported that patient was treated with Paxlovid from 26-may-2022 to 30-may-202. She was tested positive 2 days after the treatment with Paxlovid. Patient had received 2 doses of Comirnaty COVID-19 vaccine approximately 6 3 months prior to mRNA-1273 vaccination (Interchange of vaccine products). The current pandemic situation of COVID 19 may remain as confounder to the event Covid-19.  The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.