her husband received one injection to his left arm and his arm was black and blue; Periodic episodes of feeling itchy/itching to his back, abdomen, some to the upper parts of his legs/thigh area and had a little bit to his head clarified to being his scalp; This is a spontaneous report from a contactable nurse. This nurse reported similar events for two patients. This report refers to the husband.   An 80-year-old male patient received first dose of  BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) (lot number: EL3246, expiry date: 30Apr2021, NDC number of Pfizer COVID-19 vaccine: 59267- 1000-2), via an unspecified route of administration on 06Jan2021 18:00 at single dose in the left arm for COVID-19 vaccination. Medical history included joint surgery which he just had one at the end of December of last year (2020) and had a procedure in Sep (unknown year); and prostate cancer which he had surgery February last year for this. The patient's concomitant medications were not reported. The nurse (patient's wife) reported that the patient received the Covid -19 Vaccine around 6 o'clock on Wednesday evening. So basically 2 days ago and neither one of them seem to show any major reaction but yesterday sometime during the day, he started noticing a little bit of itching in his abdominal area and his back, no sign of whatsoever of a rash, there is no evidence of a rash at all but it is bothering him off and on today and she just didn't notice that was related in anyway. It's not in any of the paperwork we received and it's no rash and he is not having trouble breathing anything like that but he is having these periodic episodes of feeling itchy. When paraphrased the above concern, nurse stated, "That's right, the back, basically yes and no other area right across the abdominal area and some occasionally little bit on his leg but more often on his back and it is not constant and there is no visible rash and he doesn't have a history of drug allergies. He is not one who generally reacts and he has no temperature, his vital signs are good. They just wanted to know if something we should be concerned about or whether there is been any report of this, she asked if they should call the doctor or what should they do. On 12Jan2021, the nurse called again and she stated that on 07Jan2021 (Thursday), the patient experienced random itching and continued in to Friday.  Furthermore, she stated that the day after he got the shot, and he is 80 with no history of drug reactions he had itching to his back, abdomen, some to the upper parts of his legs/thigh area and had a little bit to his head clarified to being his scalp. She says that she went to the drug store and got him some Benadryl. She says her the itching went away then on Thursday, and the next day he works part time, so he went to work on Friday and it started again. He was better on Saturday. She would like to know if this is a possible side effect, or if there might be a problem with him getting second dose. She said that the itching was in random places, it was the second night that she gave him the Benadryl that knocked him out, clarified he was sleepy after taking the Benadryl. She says she never saw a rash on his skin, and Saturday the itching was mitigated considerably. She said on Friday night she had got a little nervous, since the patient is 80 and has some health issues but no issues with medications in the past to their knowledge. He was better the next day. She says she doesn't know if his itching was associated with the vaccine. Also reported that the patient received one injection to his left arm and his arm was black and blue afterwards. The outcome of the event "Periodic episodes of feeling itchy/itching to his back, abdomen, some to the upper parts of his legs/thigh area and had a little bit to his head clarified to being his scalp" was recovered on 09Jan2021; for event "her husband received one injection to his left arm and his arm was black and blue" was unknown.; Sender's Comments: Linked Report(s) : US-PFIZER INC-2021028800 same reporter/drug, different event