she has pulled some of the vials that were used out of the sharps container and peeled off the label to find that the dots and lines disappeared. We didn't inject the vial into the patient; This case has been considered as invalid due to no adverse effect, only product complaint.  This is a spontaneous report from a contactable pharmacist. A female patient of an unspecified age received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection, lot number: EK9231, expiry date: unknown, NDC number: 59267- 1000-1 ) via an unspecified route of administration, on an unspecified date, at 30mg/0.3mL, single for COVID-19 immunization. The patient's medical history and concomitant medications were not reported. The pharmacist reported that she has multiple vials of the COVID-19 vaccine that have either dots or fixed lines on the vials, presumably what could be a potential crack in the vial. The vials were all smooth on the outside. There are no particles and the vaccine looks normal, even after its been reconstituted. She pulled some of the vials that were used out of the sharps container and peeled off the label to find that the dots and lines disappeared. She felt that they may be a result of air trapped between the label and the vial but she states that she is not sure and would like to know if she can still use the product or should discard them. In follow-up the pharmacist reported seeing something strange in the vial after reconstituting it with the diluent. She noticed what looks like a core as she injected the syringe and on further injection, she noticed that the piece was reflecting and picking up light and this piece was not moving in the solution. And she added that there are 2 vials with this appearance, and they have the same LOT#.  Pharmacist stated, they didn't inject the vial into the patient.  Pharmacist stated, "It is not floating, it is a fixed spot on the vial where, when I look from one angle it looks like there could potentially be a core. So, it shows almost grey. When I move the vial, I can see the reflected light within the particle slightly and then if I move the vial further over where there is no fluid covering the spot, the spot is not noticeable. One vial is one spot, the other vial is a spot and what looks almost to be scraped on the inside. It is grey in color until I move the vial as such to where there is no fluid covering it, then it disappears. And when I move the vial further when there is fluid covering it, it will reflect light, so it's not really a true like particles, it's hard to describe. It is very, very small in 1 vial, may be the size like of a, I don't know like similar to like a 21 gauge needle. And then on the other vial it is one spot that's larger than that almost like the end of paper clip and then the part that almost appears to be like 'dry are faded' (voice distortion) and those are very, very faint lines. This happened after dilution of the vial with Sodium Chloride. I did not notice this prior to, I inspected the vial prior to dilution and I did not notice that either. At this point I completed the dilution around 8:55 for one of the vials and 9 o' clock for the other so.  It has been at as far as I am aware I have access to our continual monitor but we do keep a paper log of the refrigerator temp every day and it has been under refrigeration. It was removed from the ultra-low freezer at 8 o' clock on 11th, on Monday."   Follow-up (13Jan2021): New information received from a contactable pharmacist includes: clinical course and confirmed they didn't inject the vial into the patient. Sodium Chloride added as suspect drug.