COVID-19; got worse on 5/12/2022 and tested Ag positive again; This spontaneous case was reported by a consumer and describes the occurrence of COVID-19 (COVID-19) and COVID-19 (got worse on 5/12/2022 and tested Ag positive again) in a  patient of an unknown age and gender who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 073f21A, 019B21A and 032b21A) for COVID-19 vaccination.     Concurrent medical conditions included Asthma, GERD, Sinus infection, Penicillin allergy and Fruit allergy (Apples).   On 31-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 03-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-May-2022, the patient experienced COVID-19 (got worse on 5/12/2022 and tested Ag positive again). On an unknown date, the patient experienced COVID-19 (COVID-19). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) from 04-May-2022 to 08-May-2022 for COVID-19 treatment, at an unspecified dose and frequency. At the time of the report, COVID-19 (COVID-19) and COVID-19 (got worse on 5/12/2022 and tested Ag positive again) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 11-May-2022, SARS-CoV-2 test: negative (Negative) tested Ag neg 3x and negative (Negative) tested Ag neg 3x. On 12-May-2022, SARS-CoV-2 test: postive (Positive) tested Ag positive again.. On 16-May-2022, SARS-CoV-2 test: positive (Positive) still Ag positive and my symptoms were as bad as when I start.         No concomitant medication were reported. Reportedly, Patient had a rebound after taking paxlovid and tested Ag neg 3x on 11 May 2022 and got worse on 12 May 2022 and tested Ag positive again,he was still Ag positive on 16 May 2022  and his symptoms were as bad as when he started paxlovid on 04 May. The device date was reported as 16-May-2022.  Company comment: This spontaneous case concerns a patient of unknown age and gender with no relevant medical history who experienced the unexpected non serious AESIs of COVID 19 after unknown days and COVID 19(got worse on 5/12/2022 and tested Ag positive again) approximately 5 months after the administration of third dose of mRNA-1273 vaccine. Patient received NIRMATRELVIR, RITONAVIR (Paxlovid) for 5 days as treatment for COVID 19 from 04-May to 08-May and tested negative for COVID 19 on 11-May. Patient got worse on 12-May and again tested positive for COVID 19. Patient received 2 doses of mRNA-1273 vaccine approximately 7 and 8 months respectively prior to the last dose. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a patient of unknown age and gender with no relevant medical history who experienced the unexpected non serious AESIs of COVID 19 after unknown days and COVID 19(got worse on 5/12/2022 and tested Ag positive again) approximately 5 months after the administration of third dose of mRNA-1273 vaccine. Patient received NIRMATRELVIR, RITONAVIR (Paxlovid) for 5 days as treatment for COVID 19 from 04-May to 08-May and tested negative for COVID 19 on 11-May. Patient got worse on 12-May and again tested positive for COVID 19. Patient received 2 doses of mRNA-1273 vaccine approximately 7 and 8 months respectively prior to the last dose. The benefit-risk relationship of mRNA-1273 is not affected by this report.