This is a spontaneous report from a contactable consumer (the patient). This 67-year-old female patient received PREVNAR 13 intramuscularly on the right arm on 02Dec2015 at 0.5 ml single. Medical history included osteoarthritis, pre-diabetic, blood pressure abnormal (controlled by DIURIL) and hurt shoulder. The patient stated that she always had some pain due to osteoarthritis. Pain and stiffness is increased significantly a little sore, esp. feet, ankles, knee, hip (right) around Dec2007-Aug2015 and returned to normal levels around 01Jan2016. She was diagnosed with tendonitis left shoulder on 20Nov2015. She was experiencing significant improvement in pain level and motion in Dec2006 followed by symptoms listed above including greatly increased pain and stiffness in joint around Dec2007-Aug2015. Physical therapy was delayed by a scheduled vacation week. It began on 14Dec2015 and provided significant relief but she believed much less relief than would have occurred without PREVNAR 13 injection. She continued in physical therapy through the end of February. Pain was minimal, but muscle weakness and limited range of motion continued. For tendonitis, the patient has been treated by a nurse practitioner of centers for joint surgery and sports medicine. Concomitant medications included ongoing DIURIL orally at 25 mg, daily (for years) for blood pressure, probiotics (manufacturer unknown) orally from Aug2015 and ongoing not daily 3-4/wk, TYLENOL orally until 01Jan2016 at 650 mg 2x/day for pain, aspirin at 325 mg as needed (one at a time, once in a while occasionally) for pain, tramadol (manufacturer unknown) at 25 mg from 02Dec2015 to 10Dec2015 and TYLENOL P.M. from 12Dec2015 to 01Jan2016. On an unspecified date in Dec2015, the patient experienced muscle pain, joint pain, decreased appetite, fatigue, headache, chills, swelling in her wrist where her thumb attaches, she could not sleep or get comfortable, whole arm has become tender below the elbow. Additionally, the patient experienced muscle weakness and limited range of motion on an unspecified date with outcome of unknown. The patient was hospitalized for muscle pain, for joint pain, for could not sleep or get comfortable from 07Dec2015 to an unknown date; while she was hospitalized for decreased appetite, for fatigue, for headache, for chills, for swelling in her wrist where her thumb attaches, for whole arm has become tender below the elbow from 08Dec2015 to an unknown date. The patient did not receive any treatments for the events muscle pain and joint pain, decreased appetite, fatigue, headache, chills, swelling in her wrist where her thumb attaches, she could not sleep or get comfortable, whole arm has become tender below the elbow. The patient was recovering from muscle pain, joint pain, could not sleep or get comfortable, whole arm has become tender below the elbow while she recovered from decreased appetite, fatigue, headache, chills, swelling in her wrist where her thumb attaches. Follow-up (22Feb2016): New information reported from a contactable consumer includes: events details (seriousness criteria, treatment, outcome) and concomitant medications details provided, new concomitant medications added, medical history updated, new events added.