Fever; Decreased appetite; Wrong injection technique; Injection site itching; Diarrhea bloody; Injection site pain; Injection site bruising; Injection site bleeding; Arthralgia aggravated; Skin disorder; Joint crepitation; Feeling sad; Difficulty sleeping; Pain stomach; Rectal bleeding; Constipation; This is a solicited report based on the information received by Pfizer. A contactable 39-year-old male consumer (patient) reported for himself that:  DESCRIBE REACTION(S) (include relevant test/lab data) Constipation (Constipation) - Improved  Skin disorder (Skin disorder) - Not recovered/not resolved Joint crepitation (Joint noise) - Unknown  Wrong injection technique (Wrong technique in product usage process) - Unknown  Feeling sad (Depressed mood) - Worsened  Difficulty sleeping (Insomnia) - Worsened  Diarrhea bloody (Diarrhoea haemorrhagic) - Improved  Injection site itching (Injection site pruritus)- Recovered/resolved  Rectal bleeding (Rectal haemorrhage) - Not recovered/not resolved  Arthralgia aggravated (Arthralgia) - Unknown  Pain stomach (Abdominal pain upper) - Recovered/resolved Injection site pain (Injection site pain) - Unknown  Injection site bruising (Injection site bruising) - Unknown  Injection site bleeding (Injection site haemorrhage) - Unknown  Fever (Pyrexia) - Unknown  Decreased appetite (Decreased appetite) - Unknown  Solicited report by a consumer of a 39 year old male with events of non-serious Constipation, Little Mark On Skin, Shoulder Popping At Times, Might Be Did Not Hold The Humira Pen The Right Way And Angled It A Little Bit, Sometimes Felt Sad Or Blue, Almost Never Trouble Sleeping, Sometimes/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day With Minimal Blood At Times, Injection Site Itchy, Almost Never Rectal Bleeding, Joint Pain In Knees Got Worsened, Almost Never Pain In Stomach/Abdomen, Injection Site Hurt A Little And Had A Little Bruising And Blood At Site/Momentary Sting At Injection Site, Fever And Not Feeling Hungry With Humira 40mg/0.8ml (Adalimumab). The Patient Had A Relevant Medical History Of Sometimes/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day With Minimal Blood At Times, Joint Pain, Almost Never Trouble Sleeping And Felt Anxious.  On unknown dates, the patient experienced FEVER and NOT FEELING HUNGRY. In 2020, the patient experienced Constipation, Sometimes Felt Sad Or Blue, Almost Never Trouble Sleeping, Almost Never Rectal Bleeding And Almost Never Pain In Stomach/Abdomen. In Oct2020, The Patient Experienced Little Mark On Skin, Shoulder Popping At Times And Joint Pain In Knees Got Worsened. On 07Oct2020, the patient experienced Sometimes/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day With Minimal Blood At Times And Injection Site Hurt A Little And Had A Little Bruising And Blood At Site/Momentary Sting At Injection Site. In Feb2021, the patient experienced Might Be Did Not Hold the Humira Pen the Right Way and Angled It A Little Bit and Injection Site Itchy. In Feb2021, The Injection Site Itchy Resolved. On An Unknown Date, Almost Never Pain In Stomach/Abdomen Resolved. Covid-19 Vaccine Was Also Considered Suspect.  Primary Reporter Contact For Lot Number Information Was Not Available. Causality for HUMIRA 40MG/0.8ML(ADALIMUMAB) The reporter's causality for the event(s) of Constipation, Little Mark On Skin, Shoulder Popping At Times, Might Be Did Not Hold The Humira Pen The Right Way And Angled It A Little Bit, Sometimes Felt Sad Or Blue, Almost Never Trouble Sleeping, Sometimes/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day With Minimal Blood At Times, Injection Site Itchy, Almost Never Rectal Bleeding, Joint Pain In Knees Got Worsened, Almost Never Pain In Stomach/Abdomen, Injection Site Hurt A Little And Had A Little Bruising And Blood At Site/Momentary Sting At Injection Site Onset 07Oct2020, Injection Site Hurt A Little And Had A Little Bruising And Blood At Site/Momentary Sting At Injection Site Onset 07Oct2020, Injection Site Hurt A Little And Had A Little Bruising And Blood At Site/Momentary Sting At Injection Site Onset 07Oct2020, Fever And Not Feeling Hungry Was Not Provided. Change History On 08Dec2020, Received Updates To Patient Demographics, Event Information, Reporter Opinion Of Causality, Suspect Drug Information And Narrative Description. The Event Of Almost Never Rectal Bleeding Was Added. The Event Of Injection Site Hurt Was Amended To Injection Site Hurt/Momentary Sting At Injection Site. The Event Of Sometimes Diarrhea/Occasional Diarrhea But Generally Loose Stools One To Three Times A Day With A Minimal Blood At All Times Was Amended To Sometimes Diarrhea/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day, Might Be One Time A Week Stools A Little Loose With A Minimal Blood. On 23Feb2021, Received Updates To Medical History, Event Information, Reporter Opinion Of Causality, Suspect Drug Information And Narrative Description. The Events Of Sometimes Felt Sad or Blue and Almost Never Trouble Sleeping Were Added. The Event Of Joint Pain In Knees Was Amended To Constipation. The Event Of Sometimes Diarrhea/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day, Might Be One Time A Week Stools A Little Loose With A Minimal Blood Was Amended To Little Mark On Skin. The Event Of Injection Site Hurt/Momentary Sting At Injection Site Was Amended To Might Be Did Not Hold The Humira Pen The Right Way And Angled It A Little Bit. The Event Of Injection Site Bruising Was Amended To Sometimes/Occasional Diarrhea But Generally Loose Stools Two To Four Times A Day With Minimal Blood At Times. The Event Of Shoulder Popping At Times Was Amended To Injection Site Itchy. The Event of Almost Never Rectal Bleeding Was Amended To Joint Pain In Knees Got Worsened. The Event Of Injection Site Blood Was Amended To Almost Never Pain In Stomach/Abdomen. On 16Apr2021, Received Updates To Event Information, Reporter Opinion of Causality, Suspect Drug Information and Narrative Description. The Events Of Fever And Not Feeling Hungry Were Added.  No follow-up attempts are possible. Information about lot/batch number cannot be obtained.  The reporter's assessment of the causal relationship of the event  with BNT162B2 was not provided at the time of the report.  Since no determination has been received, the case is managed based on the company causality assessment.; Sender's Comments: Based on a compatible temporal association and known product safety profile, there was a reasonable possibility that the reported events of Insomnia, vaccination site pruritus, vaccination site bruising, vaccination site hemorrhage, vaccination site pain, arthralgia, and fever were related to BNT162B2 vaccine. All other reported events are attributed to underlying or intercurrent medical conditions and assessed unrelated to BNT162B2 vaccine.