unbelievably itchy, very significant itching fom right elbow to shoulder; Very significant redness from right elbow to shoulder; Very significant swelling from right elbow to shoulder; A local reaction on her right arm where she was injected; right arm was tender at the injection site as expected; tired; This spontaneous case was reported by a nurse and describes the occurrence of PRURITUS (unbelievably itchy, very significant itching fom right elbow to shoulder), ERYTHEMA (Very significant redness from right elbow to shoulder), PERIPHERAL SWELLING (Very significant swelling from right elbow to shoulder), VACCINATION SITE REACTION (A local reaction on her right arm where she was injected) and FATIGUE (tired) in a 72-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 031M20A and 001B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Food allergy, Adhesive tape use, Osteopenia since 28-Jan-2011, Vitamin D deficiency since 05-Sep-2019, Basal cell carcinoma since 02-Feb-2013, Food allergy, Food allergy and Alcohol allergy. Concomitant products included HYDROCHLOROTHIAZIDE, TRIAMTERENE (TRIAMTERENE/HCTZ) from 28-Jan-2011 to an unknown date for Calcium supplementation, CALCIUM, COLECALCIFEROL (CALCIUM & VITAMIN D [CALCIUM;COLECALCIFEROL]) for Osteopenia, VITAMIN D NOS from 09-May-2014 to an unknown date for Vitamin D deficiency, MULTIVITAMINS [VITAMINS NOS] and ACETYLSALICYLIC ACID (ASPIRIN 81) for an unknown indication.   On 10-Feb-2021 at 11:30 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 10-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 10-Feb-2021, the patient experienced FATIGUE (tired). On 17-Feb-2021, the patient experienced PRURITUS (unbelievably itchy, very significant itching fom right elbow to shoulder), ERYTHEMA (Very significant redness from right elbow to shoulder), PERIPHERAL SWELLING (Very significant swelling from right elbow to shoulder), VACCINATION SITE REACTION (A local reaction on her right arm where she was injected) and VACCINATION SITE PAIN (right arm was tender at the injection site as expected). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency. On 21-Feb-2021, PRURITUS (unbelievably itchy, very significant itching fom right elbow to shoulder), ERYTHEMA (Very significant redness from right elbow to shoulder), PERIPHERAL SWELLING (Very significant swelling from right elbow to shoulder) and VACCINATION SITE REACTION (A local reaction on her right arm where she was injected) had resolved. At the time of the report, FATIGUE (tired) and VACCINATION SITE PAIN (right arm was tender at the injection site as expected) outcome was unknown.        mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosing remained unchanged.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   This case was linked to MOD-2021-062104 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 09-May-2021: Reporter details, patient demographics, medical history, product details, event information updated On 11-May-2021: Event details updated