Booster; Wife developed Covid 19 after having 1st 2nd and booster dose; Drug ineffective; Sore arm and armpit; Sore arm and armpit; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A male patient in his 70's received bnt162b2 (COMIRNATY), administered in arm, administration date 05Oct2021 (Batch/Lot number: unknown) as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Asthma" (unspecified if ongoing), notes: Caller is being careful, he has asthma; "Bronchitis" (unspecified if ongoing), notes: Has tender lungs because of former bronchitis and asthma. Concomitant medication(s) included: FLU VACCINE VII taken for immunisation, administration date 21Sep2021. Vaccination history included: Bnt162b2 (Dose 2), for Covid-19 immunization; Bnt162b2 (Dose 1), for Covid-19 immunization. The following information was reported: IMMUNISATION (medically significant) with onset 05Oct2021, outcome "unknown", described as "Booster"; COVID-19 (medically significant) with onset 2021, outcome "unknown", described as "Wife developed Covid 19 after having 1st 2nd and booster dose"; DRUG INEFFECTIVE (medically significant) with onset 2021, outcome "unknown", described as "Drug ineffective"; AXILLARY PAIN (non-serious), PAIN IN EXTREMITY (non-serious) all with onset 2021, outcome "unknown" and all described as "Sore arm and armpit". The patient underwent the following laboratory tests and procedures: sars-cov-2 test: negative, notes: Caller tested negative for COVID-19 yesterday. Was told he has to wait until Friday or Saturday to test again so it would be 5 days from exposure.  Clinical information: It was reported that wife developed Covid 19 after having 1st 2nd and booster dose of Pfizer COVID 19 vaccine. Caller is the husband who stated that he and his wife, (Name withheld), have been vaccinated with Pfizer Covid 19 vaccine 1st, 2nd, and booster dose (given on 05Oct2021). He states that they are both in their 70s. He relays that almost 13 weeks to the day his wife came down with what seemed like a head cold and she tested positive for Covid 19 virus. He has not tested positive but will retest in 3 days. Reporter asked what is the occurrence rate of breakthrough infections with both initial doses and a booster dose. He have read that efficacy decreases 10 weeks after getting the booster dose, is that true. Caller is a consumer reporting a breakthrough infection of COVID-19 after receiving first, second, and booster dose of Comirnaty. Caller's wife, (Name withheld), is also on the line. Both are in their mid-seventies. Booster dose was on 25Oct2021. 13 weeks after the booster dose, (Name withheld) tested positive for COVID-19. (Name withheld) has not tested positive and will be retesting in three days. The caller confirmed the details provided by the transfer agent. Caller and his wife are both on the line providing report details. Patient in this report is the caller. Caller clarified he and his wife had the booster dose of Comirnaty on 05Oct2021, not 25Oct2021. Received the booster dose at a local hospital. Almost 13 weeks to the day, the patient started sneezing like she had a massive head cold. By 13:00 on Monday, caller and the patient did an at-home COVID-19 test by Abbott. States the patient's COVID-19 test had a strong positive line, it was not a faint line. They contacted the hospital and was advised to stay home and what to do if it got worse. Caller tested negative for COVID-19 yesterday. Was told he has to wait until Friday or Saturday to test again so it would be 5 days from exposure. 21Oct2021 caller had his Flu shot. He waited 2-3 weeks after the third dose of the Comirnaty. Caller had a sore arm after the Comirnaty. It was sore in the arm and the armpit. States had no reaction to the flu vaccine. Caller is being careful, he has asthma. Does not have COPD. Has tender lungs because of former bronchitis and asthma. If he gets COVID, hopes it's extremely mild. He is worried. As far as caller's sore arm from 13 weeks ago, he states he would expect that.  The lot number for bnt162b2 was not provided and will be requested during follow up.