Home and Rapid RT/PCR tests continued to show positive; This spontaneous case was reported by a patient and describes the occurrence of COVID-19 (Home and Rapid RT/PCR tests continued to show positive) in a 66-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Drug allergy.   On 20-Jan-2021 at 9:00 AM, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Feb-2021 at 9:00 AM, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 03-Oct-2021 at 1:00 PM, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced COVID-19 (Home and Rapid RT/PCR tests continued to show positive). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) from 24-May-2022 to 30-May-2022 for COVID-19 treatment, at an unspecified dose and frequency. At the time of the report, COVID-19 (Home and Rapid RT/PCR tests continued to show positive) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 04-Jun-2022, Body temperature: 99.4 (High) 99.4. On an unknown date, SARS-CoV-2 test: positive (Positive) Positive.         No concomitant medications were reported.  The patient did not take any other medications/products within 2 weeks of starting COVID-19 treatment. The patient had previously received a COVID-19 Vaccine. The patient took Paxlovid evening of 24-MAY-2022 17:00 through morning of 30-MAY-2022. Symptoms were gone by 27-MAY-2022 but cough lingered, and home and Rapid RT/PCR tests continued to show positive. Symptoms worsened on 04-JUN-2022 with slight fever (99.4), congestion and bad cough through 06-JUN-2022. Home antigen tests continue to show positive every day. Device Date : 06-Jun-2022  Company Comment: This Spontaneous case concerns a 66-year-old male patient, with no relevant medical history, who experienced the unexpected, non-serious AESI of COVID-19, which occurred on an unknown date after a dose of mRNA-1273 vaccine. The patient received 5-day treatment for COVID-19 with Nirmatrelvir, Ritonavir (Paxlovid), approximately 7 months and 3 weeks after a dose of mRNA-1273 vaccine. Symptoms were gone 3 days after start of Paxlovid, but cough lingered, and rapid RT/PCR tests continued to show positive. Symptoms worsened with slight fever, congestion and bad cough. Additional information was solicited for accurate and complete medical review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This Spontaneous case concerns a 66-year-old male patient, with no relevant medical history, who experienced the unexpected, non-serious AESI of COVID-19, which occurred on an unknown date after a dose of mRNA-1273 vaccine. The patient received 5-day treatment for COVID-19 with Nirmatrelvir, Ritonavir (Paxlovid), approximately 7 months and 3 weeks after a dose of mRNA-1273 vaccine. Symptoms were gone 3 days after start of Paxlovid, but cough lingered, and rapid RT/PCR tests continued to show positive. Symptoms worsened with slight fever, congestion and bad cough. Additional information was solicited for accurate and complete medical review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.