UTI (urinary tract infection) with extreme pain and it wouldn't go away for six weeks; UTI (urinary tract infection) with extreme pain and it wouldn't go away for six weeks; Patient also now have issues with emptying her bladder; She had the worst insomnia she'd ever had; Patient have IBS and SIBO both these conditions worsened starting about five days after the second vaccine; Patient have IBS and SIBO both these conditions worsened starting about five days after the second vaccine; Patient have IBS and SIBO both these conditions worsened starting about five days after the second vaccine; Nauseous; Had no appetite; Lost about twelve pounds; This is a spontaneous report from a contactable consumer (patient). This consumer reported similar events for two patients. This is the first of two reports.     A 59-year-old female patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration, administered in right arm on 02Apr2021 11:00 (Batch/Lot Number: ER8737) (at the age of 59 years old) as single dose for Covid-19 immunisation. Medical history included high blood pressure (HBP), irritable bowel syndrome (IBS), gastrointestinal bacterial overgrowth (SIBO), anxiety, depression, severe neck stenosis, and urinary tract infection (UTI) (typically gets 3 UTIs in a year), all from unknown date and unknown if ongoing. No other vaccine in four weeks. The patient was not pregnant at the time of vaccination. The first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) was administered on 03Mar2021 at 2pm (lot number: EN6208) (at the age of 59 years old), via an unspecified route of administration, administered in left arm for Covid-19 immunization. Concomitant medications included bupropion taken for an unspecified indication, start and stop date were not reported; alprazolam taken for an unspecified indication, start and stop date were not reported; omeprazole taken for an unspecified indication, start and stop date were not reported. The patient experienced UTI (urinary tract infection) with extreme pain and it wouldn't go away for six weeks, patient also now have issues with emptying her bladder, she had the worst insomnia she'd ever had, patient have IBS (Irritable bowel syndrome aggravated) and SIBO (Small intestinal bacterial overgrowth), both these conditions worsened starting about five days (as reported) after the second vaccine, she was nauseous, had no appetite, and lost about twelve pounds, all these on 07Apr2021 at 01:00 (as reported). The clinical course was reported as follows: The medical issues the patient was dealing with were amplified 100%. She typically gets 3 UTIs in a year, five days after her second vaccine (07Apr2021), she got a UTI with extreme pain and it wouldn't go away for six weeks. Patient tried five different antibiotics to get rid of it. She also now has issues with emptying her bladder. She had IBS and SIBO, both these conditions were worse starting about five days after the second vaccine. She was nauseous for the first three months and had no appetite and lost about twelve pounds. She had the worst insomnia she'd ever had. She did not sleep more than three hours a night for the first two months. The adverse events resulted in doctor or other healthcare professional office/clinic visit and emergency room/department or urgent care. Treatment for the adverse events were antibiotics, sleeping pills (trazadone), Zofran, Lexipro, and gabapentin. The patient did not have Covid-19 prior vaccination. The patient was tested for Covid-19 post vaccination. The patient underwent lab tests which included NAA 2 day TAT: negative (nasal swab), and Rapid: negative (nasal swab), both on 20Jul2021. Outcome of the events was recovering.; Sender's Comments: Linked Report(s) : PFIZER INC-202100973389 Same reporter, product and event, different patient