heavy menstrual bleeding; nerve pain throughout my body; I had shooting pains down both legs; extreme fatigue/extremely tired; joint and muscle pain all over my body/ My fingers, wrist, knees, ankles, neck and feet hurt; joint and muscle pain all over my body; Weak; 60 day gap between menstrual periods; This is a spontaneous report from a contactable consumer (patient) reported for herself. A 44-years-old female patient (patient was not pregnant at the time of vaccination) received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EW0172, Expiration date: unknown) intramuscular, administered in left arm on 25Apr2021 at 12:15 pm (age at vaccination was 44 years) as dose 2, single for COVID-19 immunization. The patient did not have any medical history. The patient did not have any known allergies. The patient did not have any underlying health issues. The patient's family medical history relevant to adverse events was unknown. The patient did not receive any concomitant medications or other medications in two weeks. The patient previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EW0150, Expiration date: unknown) intramuscular, administered in left arm on 04Apr2021 at 12:15 pm (age at vaccination was 44 years) as dose 1, single for COVID-19 immunization and twelve hours after the first dose, the patient developed a migraine, headache which lasted on and off for a day. The facility where the most recent COVID-19 vaccine was administered was Pharmacy. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Prior to vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient has not been tested for COVID-19. The patient felt fine for the first 24 hours after her second dose. After having her second dose of Pfizer COVID vaccine, the patient had a 60 day gap between menstrual periods. The patient had her menstrual period on 22Apr2021 and received the second dose of Pfizer vaccine during her period on 25Apr2021. She did not have her next menstrual period until 21Jun2021 (over 60 days gap). She did not have a menstrual period for 60 days after her second dose. She had never before had a missed period, never had a late period, never been pregnant, and she had no history of gynecological issues whatsoever. This was the first and only time that she had missed a menstrual period. She had no underlying health issue and did not take any medications. The next menstrual cycle (after the missed period) was normal, except that she experienced unusually heavy menstrual bleeding. That was very unusual for her. She has always had a very consistent 28 day cycle and she was concerned by this abnormality following her second dose of the COVID vaccine. She took an over the counter pregnancy test after she missed period and it was negative. This was highly unusual for her and she was very concerned. On 26Apr2021 at 11:00 am, at 24 hours, the patient began to feel extremely tired and weak with muscle joint and nerve pain throughout her body. The patient experienced extreme fatigue, joint and muscle pain all over her body, beginning 24 hours after the second dose and subsiding at 36 hours, although that side effect did not concern her as greatly as the 60 day gap between menstrual periods. Her fingers, wrist, knees, ankles, neck and feet hurt. She had shooting pains down both legs. She slept for 18 hours and then felt better when she awakes. No treatment was received for the adverse events. No relevant tests were done. The case was assessed as non-serious. The outcome of the events 60 day gap between menstrual periods, extreme fatigue/extremely tired, and joint and muscle pain all over my body/my fingers, wrist, knees, ankles, neck and feet hurt, and joint was resolving. The outcome of the other events was unknown.  Follow-up attempts are completed. No further information is expected.