cellulitis; Caller can't walk on their own without a cane or a walker because their legs have gotten so weak.; three weeks after the shot they started getting redness on legs from ankles up to their knee. skin was starting to get redder and harder; Then she went to her primary care and they said she had lymphedema; This spontaneous case was reported by a patient and describes the occurrence of CELLULITIS (cellulitis) and GAIT INABILITY (Caller can't walk on their own without a cane or a walker because their legs have gotten so weak.) in an 80-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 025A21A and 026B21A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     Previously administered products included for Drug use for unknown indication: hydrocortisone (hydrocortisone makes her pass out) since an unknown date. Past adverse reactions to the above products included No adverse event with hydrocortisone. Concurrent medical conditions included Vegetable allergy (Allergic to cucumbers), Food allergy (Allergic to pickles), Diabetes (for a long time and taking insulin Novolin 25 units in the morning and before dinner.) and Drug allergy (Levaquin allergy). Concomitant products included IRBESARTAN for Blood pressure management, ROSUVASTATIN CALCIUM (CRESTOR) for Cholesterol, ASCORBIC ACID, TOCOPHERYL ACETATE, XANTOFYL, ZEAXANTHIN, ZINC (AREDS) for Retinopathy, ASPIRIN [ACETYLSALICYLIC ACID], IRON, UBIDECARENONE (COQ10 [UBIDECARENONE]), COBAMAMIDE (VITAMIN B12 [COBAMAMIDE]), VITAMIN B6 and MACROGOL 3350 (MIRALAX) for an unknown indication.   On 06-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In 2021, the patient experienced CELLULITIS (cellulitis) (seriousness criterion medically significant), GAIT INABILITY (Caller can't walk on their own without a cane or a walker because their legs have gotten so weak.) (seriousness criterion medically significant), ERYTHEMA (three weeks after the shot they started getting redness on legs from ankles up to their knee. skin was starting to get redder and harder) and LYMPHOEDEMA (Then she went to her primary care and they said she had lymphedema). At the time of the report, CELLULITIS (cellulitis), GAIT INABILITY (Caller can't walk on their own without a cane or a walker because their legs have gotten so weak.), ERYTHEMA (three weeks after the shot they started getting redness on legs from ankles up to their knee. skin was starting to get redder and harder) and LYMPHOEDEMA (Then she went to her primary care and they said she had lymphedema) had not resolved.     Company comment: This spontaneous case concerns an 80-year-old female patient with no medical history reported, who experienced the unexpected, serious (medically significant), events of cellulitis and gait inability and received two doses of mRNA-1273 within the appropriate schedule of vaccination. The event onset date was not provided. It was reported that three weeks after the shot, she started getting redness on legs from ankles up to her knee. Skin was starting to get redder and harder. They went to vascular doctors and they did know why she got it. Then she went to her primary care, and they said she had lymphedema. They ordered her to put on compression boots and other treatments. Doctor said to make sure not to shave the skin. She needed help her to put a cream on, they can't bend her leg to put cream on the leg. It looked like cellulitis, legs were dark beet red. HCP told them not to go into the sun with it. She can't walk on her own without a cane or a walker because her legs have gotten so weak. She used to be very active. No further clinical information was provided for review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.         Patient received the Moderna shot on 06 Mar 2021 and 31 Mar 2021, three weeks after the shot she started getting redness on legs from ankles up to their knee. skin was starting to get redder and harder. She went to vascular doctors, and they did know why she got it. Then she went to her primary care, and they said she had lymphedema. They ordered her to put on compression boots and other treatments. She was not able to wear shorts and her skin was so hard. Doctor said make sure not to shave the skin. She had an aid to help her put a cream on, they cannot bend their leg to put cream on the leg. She was 80 years old now and kept quiet all this while. It looked like cellulitis; legs were dark beet red. HCP told them not to go into the sun with it. She was getting more and more frustrated with the cost for the vascular appointment. She was not able to walk on their own without a cane or a walker because their legs was gotten so weak. She used to be very active. It cost her money to buy the walkers.