Nausea; Sweating; Shortness of breath; It's going from hot, cold goosebumps; Not been able to run; Elbow, back, knee, ankle pain; Sleeping during the day, take a nap or be in the bed was quite unusual; Normal cough-cold; Fatigue; Hot flashes; chills; Change in heart rate; Muscle soreness and tightness; Muscle soreness and tightness; Whole body joint pain; This is a spontaneous report from a contactable other hcp. A 49-years-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection) dose 2 intramuscular, administered in Arm Left on 25Jan2021 09:45 (Batch/Lot Number: EL9262) as single dose for covid-19 immunisation. The patient had no allergies to medications, food, or other products. There were no concomitant medications.   The patient told that she experienced extreme fatigue, hot flashes, change in heart rate anywhere from normal baseline to heart rate 160s and without exercising heart rate goes up to 120, hot flashes, not really chills. She never really had a fever after the second dose and never got a headache. But she got the vaccine on the Monday morning at 9:45 at midnight at that night woke up and had chills and was like okay. Took temperature and had no fever. Took Tylenol and Motrin and slept for the next 24 hours, woke up. Pretty much slept 24 hours. It was normal kind of normal cough-cold, extreme fatigue. Got up Wednesday was okay normal activities by 3 o clock in the afternoon again was out for the work and worked 12 hour shift the next day was off and then. Patient stated that she online looked for side effects for COVID-19 vaccine. She received both doses. So first vaccine was on 05Jan and the second vaccine was on 25Jan at 9:45 in the morning. At midnight, Monday night, after the vaccine about 16 hours, woke up with chills. So felt like she had fever but was not having fever, was extremely hot sweaty, but no fever, actual temperature. As expected, was like - okay, these are just normal side effects. She took Tylenol and Motrin at that time and got back to bed. She slept all night and then was just asleep, pretty much slept the whole next day. She slept and got up, with some nausea, typical normal side effects to be expected. She woke up Wednesday, felt okay. Again, by Wednesday evening, started having extreme fatigue, went back to bed. She slept from 3 in the afternoon to the next day and had to work at the hospital on Thursday, worked 12 hours shift. It was Friday again, extreme fatigue, heard these all are normal side effects for about the first week. So, did not pay much attention to it. Patient further stated: and when I say extreme fatigue, I am a person that does not nap or sleep during the day. So for me to take a nap or be in the bed was quite unusual. So anyways, I noticed hot flashes continued and chills. And when I say chills it is not, it kind of gets like chill cold. I think it's going from hot, cold goosebumps, never a fever but extreme hot flashes, sweating, full body sweat, and noticed kind of like increases in my heart rate when I got hot, I am sure that's just normal, and that continued, and has continued now since the vaccine. It's not, the hot flashes are continuing. It's random that's just not in the night or not just during the day, they are kind of all over the place. They happen from like every half an hour on a bad day, to I might be able to get thought at night, sleeping all night, to 3 times a day, extreme fatigue. I usually run 4 to 5 miles every day, I have not been able to run. I have shortness of breath, the heart rate kind of increases, I tracked it. Normally, I run 50-60 at resting heart rate and without exercise it will shoot up to the 120 and it is random throughout the day. I am going in today, just to get some standard blood work to see, you know, what's going on. And again, just extreme fatigue, muscle soreness, elbow, back, knee, ankle pain, joint pain, not really joint pain, but just you know, that kind of.' Consumer was informed about the role of Pfizer Drug Safety. Consumer stated, I called this morning and was disconnected, I was speaking to somebody and was disconnected.' (Not further clarified, hence, captured as Initial Report.)  The patient stated, Yes, I had no symptoms prior to the second vaccine. I did not really have anything from the first vaccine, it started like I said, about 16 hours after the initial vaccine like, woke me up at night at 12:30 am and I have been experiencing this since the vaccine, the second vaccine.'  The patient stated, I got the vaccine at 25Jan2021, since I got the vaccine so this is week number 3. The patient didn't receive any other vaccines within 4 weeks prior to the COVID vaccine.  Prior to vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient had not been tested for COVID-19. The patient underwent lab tests and procedures which included body temperature: no fever, heart rate: 160s, heart rate: 120. Therapeutic measures were taken as a result of chills (chills) , sweating (hyperhidrosis).  The outcome of events fatigue, hot flashes, chills, change in heart rate, muscle soreness and tightness, whole body joint pain was recovering and for other events was unknown.