Vomiting; diarrhea; body aches; skin hurt; unable to eat or drink; almost totally lost my voice; numb feet and ankles; rash on my legs; swollen lymph nodes; might have Guillame-Barre; was violently ill; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 66 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 27Mar2021 11:00 (Lot number: ER8727) at the age of 66 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Rheumatoid arthritis" (unspecified if ongoing). Concomitant medication(s) included: METHOTREXATE; PREDNISONE; FOLIC ACID; TYLENOL. Past drug history included: Statins, reaction(s): "allergy". Vaccination history included: Bnt162b2 (dose 1, lot number=EN6206, administration time is 11:00 , vaccine location: Left arm), administration date: 06Mar2021, when the patient was 66 years old, for COVID-19 immunization, reaction(s): "rash on my legs", "voice became very scratchy", "feet also felt a little numb". The following information was reported: GUILLAIN-BARRE SYNDROME (hospitalization, disability, medically significant), outcome "not recovered", described as "might have Guillame-Barre"; MALAISE (hospitalization, disability) with onset Mar2021, outcome "not recovered", described as "was violently ill"; VOMITING (hospitalization, disability), outcome "not recovered", described as "Vomiting"; DIARRHOEA (hospitalization, disability), outcome "not recovered", described as "diarrhea"; PAIN (hospitalization, disability), outcome "not recovered", described as "body aches"; PAIN OF SKIN (hospitalization, disability), outcome "not recovered", described as "skin hurt"; FEEDING DISORDER (hospitalization, disability), outcome "not recovered", described as "unable to eat or drink"; APHONIA (hospitalization, disability), outcome "recovering", described as "almost totally lost my voice"; HYPOAESTHESIA (hospitalization, disability), outcome "not recovered", described as "numb feet and ankles"; RASH (hospitalization, disability), outcome "recovered", described as "rash on my legs"; LYMPHADENOPATHY (hospitalization, disability), outcome "not recovered", described as "swollen lymph nodes". The patient was hospitalized for guillain-barre syndrome, malaise, vomiting, diarrhoea, pain, pain of skin, feeding disorder, aphonia, hypoaesthesia, rash, lymphadenopathy (start date: 26Apr2021, hospitalization duration: 5 day(s)). The events "might have guillame-barre", "was violently ill", "vomiting", "diarrhea", "body aches", "skin hurt", "unable to eat or drink", "almost totally lost my voice", "numb feet and ankles", "rash on my legs" and "swollen lymph nodes" were evaluated at the physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: sars-cov-2 test: unknown result, notes: post vaccination. Therapeutic measures were not taken as a result of guillain-barre syndrome, malaise, vomiting, diarrhoea, pain, pain of skin, feeding disorder, aphonia, hypoaesthesia, rash, lymphadenopathy.  Clinical course: The patient did not receive other vaccine in four weeks.The patient went on and got the second shot on 27Mar2021. In the middle of the night after receiving the second vaccine, she was violently ill. Vomiting, diarrhea, body aches and even her skin hurt, she was unable to eat or drink for over two days. Then the patient almost totally lost her voice, had numb feet and ankles, a rash on legs and swollen lymph nodes. She went to rheumatoid arthritis doctor who was concerned that she might have Guillame-Barre and recommended to go the emergency room. The patient spent in the hospital on 26Apr2021. No one seemed to know what was wrong with her. She was subjected to almost every medical test available. Eventually her rash went away, voice improved some what and she was negative for Guillame-Barre. Unfortunately, she still had swollen lymph nodes and his feet were still numb. The patient had not Covid prior vaccination. The patient had Covid tested post vaccination.