syncope; blood pressure; Can't regulate her body temperature; Chronic pain; long term chronic lyme disease came back; Heart issues; Fractured lower back; Dysautonomia; Ear ache; 3 active infections; POTS; Parkinson's like symptoms; Migraines; Chronic stomach problems; Major memory loss; Neurological issues; Can hardly walk; Slight brain damage; Major brain loss; Debilitated; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 53-year-old female patient received BNT162b2 (BNT162B2), on 24Dec2021 as dose 3 (booster), single (Lot number: 33130BA) at the age of 53 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Bipolar disorder", start date: 1999 (unspecified if ongoing), notes: Illness/AE: Bipolar disorder, Onset Date: Diagnosed in 1999, Stop Date: Unknown, Pertinent Details: she found out that the tick bite she had that went untreated in 1998 turns out it's not bipolar she has; this is stemming from the dysautonomia and lyme disease.; "Fibromyalgia" (ongoing), notes: Illness/AE: Fibromyalgia, Onset Date: Few years ago, Stop Date: Ongoing; "Degenerative disc disease", start date: 2007 (ongoing), notes: Illness/AE: Degenerative disc disease, Onset Date: 2007, Stop Date: Ongoing, Pertinent Details: Occurred after she fell in 2007.; "Neuropathy", start date: 2007 (ongoing), notes: Illness/AE: Neuropathy , Onset Date: 2007, Stop Date: Ongoing, Pertinent Details: From a slip and fall she had on her graduation day in 2007; "Asthma" (ongoing), notes: Illness/AE: Asthma, Onset Date: All her life, Stop Date: Ongoing; "Neck surgery", start date: 2007, stop date: 2007, notes: Illness/AE: Neck surgery, Onset Date: 2007, Stop Date: 2007, Pertinent Details: She needs neck surgery again; "Fractured lower back that went undiagnosed", start date: 2007 (ongoing), notes: Illness/AE: Fractured lower back that went undiagnosed, Onset Date: 2007, Stop Date: Ongoing, Pertinent Details: Occurred when she fell in 2007.; "Long term chronic Lyme disease", start date: 1998 (ongoing), notes: Start Date: 1998, Continuing: True, Comments: Long term chronic Lyme disease. The patient's family history included: "Dementia" (unspecified if ongoing), notes: Grandmother on the (ethnicity withheld) side of the family had dementia; "Parkinson's" (unspecified if ongoing), notes: She believes her great grandfather had Parkinson's. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Second dose: Date administered: 22Apr2021, Lot: 6W0170 or could be an EW0170, it is not clear on the CDC vaccine record card.), administration date: 22Apr2021, when the patient was 53-year-old, for COVID-19 immunization, reaction(s): "her long term chronic lyme disease came back", "Dysautonomia", "Slight brain damage", "Heart issues", "Can't regulate her body temperature", "Syncope", "Chronic pain", "Debilitated", "Ear ache", "Infection", "POTS", "Parkinson's like symptoms", "Migraines", "Chronic stomach problems", "Major memory loss", "Can hardly walk", "blood pressure"; Bnt162b2 (First dose: Date administered: Either 22Mar2021 or 23Mar2021, she can't read the CDC vaccine record card clearly because of their bad handwriting.), administration date: Mar2021, when the patient was 52 years old, for COVID-19 immunization.  The following information was reported: INFECTION (non-serious) with onset 2021, outcome "unknown", described as "3 active infections"; GAIT DISTURBANCE (non-serious) with onset 2021, outcome "unknown", described as "Can hardly walk"; TEMPERATURE REGULATION DISORDER (hospitalization) with onset 2021, outcome "unknown", described as "Can't regulate her body temperature"; PAIN (hospitalization) with onset 2021, outcome "unknown", described as "Chronic pain"; GASTRIC DISORDER (non-serious) with onset 2021, outcome "unknown", described as "Chronic stomach problems"; ASTHENIA (disability) with onset 2021, outcome "unknown", described as "Debilitated"; AUTONOMIC NERVOUS SYSTEM IMBALANCE (non-serious) with onset 2021, outcome "unknown", described as "Dysautonomia"; EAR PAIN (non-serious) with onset 2021, outcome "unknown", described as "Ear ache"; CARDIAC DISORDER (hospitalization) with onset 2021, outcome "unknown", described as "Heart issues"; CEREBRAL ATROPHY (medically significant) with onset 2021, outcome "unknown", described as "Major brain loss"; AMNESIA (non-serious) with onset 2021, outcome "unknown", described as "Major memory loss"; MIGRAINE (non-serious) with onset 2021, outcome "unknown", described as "Migraines"; NERVOUS SYSTEM DISORDER (non-serious) with onset 2021, outcome "unknown", described as "Neurological issues"; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (non-serious) with onset 2021, outcome "unknown", described as "POTS"; PARKINSONISM (non-serious) with onset 2021, outcome "unknown", described as "Parkinson's like symptoms"; BRAIN INJURY (medically significant) with onset 2021, outcome "unknown", described as "Slight brain damage"; LYME DISEASE (hospitalization, medically significant, life threatening) with onset 2021, outcome "unknown", described as "long term chronic lyme disease came back"; SYNCOPE (hospitalization, medically significant), outcome "unknown"; BLOOD PRESSURE ABNORMAL (hospitalization), outcome "unknown", described as "blood pressure"; SPINAL FRACTURE (medically significant), outcome "unknown", described as "Fractured lower back". The patient was hospitalized for cardiac disorder, syncope, blood pressure abnormal (start date: May2022, discharge date: 2022); for temperature regulation disorder, pain (start date: 2022, discharge date: 2022). The events "long term chronic lyme disease came back", "slight brain damage", "major brain loss", "debilitated", "fractured lower back", "dysautonomia", "ear ache", "3 active infections", "pots", "parkinson's like symptoms", "migraines", "chronic stomach problems", "major memory loss", "neurological issues" and "can hardly walk" required physician office visit. The events "heart issues", "syncope", "blood pressure", "can't regulate her body temperature" and "chronic pain" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Bartonella test: (30Jun2022) Positive, notes: Result: Positive detected 2 or more; Unit: Not Provided; Blood immunoglobulin G: (30Jun2022) Positive, notes: Result: 320 positive active; Unit: Not Provided; Blood immunoglobulin M: (30Jun2022) Positive, notes: Result: Positive detected 2 or more TBRF borrelia species; Unit: Not Provided; (30Jun2022) Positive, notes: Result: Positive for lyme; Unit: Not Provided; (30Jun2022) or more of the starred bands are present, notes: Result: 2 or more of the starred bands are present; Unit: Not Provided; (30Jun2022) Positive, notes: Result: US generous burgdorferi positive; Unit: Not Provided; Blood pressure measurement: (unspecified date) Unknown results; Body temperature: (unspecified date) Unknown results, notes: can't regulate her body temperature; Borrelia test: (30Jun2022) Positive, notes: Result: Positive; Unit: Not Provided; (30Jun2022) indecisive she guessed, they were unsure, notes: Result: Inc-for indecisive she guessed, they were unsure; Unit: Not Provided; (30Jun2022) Positive, notes: Result: Positive; Unit: Not Provided; Immunology test: (30Jun2022) Positive, notes: Result: positive for ELISA lyme disease; Unit: Not Provided; Magnetic resonance imaging: (2022) brain is damaged, notes: Result: Part of her brain is damaged; Unit: Not Provided. Clinical course included: Vaccination facility type was noted as pharmacy. Vaccine administered at military facility was noted as no. Time the vaccination was given: was unknown. Additional vaccines administered on same date of the Pfizer suspect-If applicable, list all vaccines administered on same date with the Pfizer vaccine considered as suspect was noted as none. Prior Vaccinations (within 4 weeks) If applicable, list any other vaccinations within four weeks prior to the first administration date of the suspect vaccine(s) was noted as none. The Pfizer Covid-19 Vaccine was mandated; she did not want it. She has been to many different specialists and these events are all pointing back to the vaccine that she was told she had to take in order to fly. The patient was very upset and angry. She said that she received Pfizer Covid-19 Vaccine as well the booster shot, and this was the reason why she was experiencing everything. She did not mention specific situation or what happened to her. She had done every test and it was pointing to the Pfizer Covid-19 Vaccine. She clarified that she has had 3 doses of Pfizer Covid-19 Vaccine including 1 booster shot. She reported after being administered the products all of her symptoms started including: her long term chronic lyme disease came back; Dysautonomia; Neurological issues; Heart issues; Ear ache; Debilitated; slight brain damage; 3 active infections; POTS; Parkinson's like symptoms; migraines; chronic stomach problems; chronic pain; major brain loss; major memory loss; can hardly walk; can't regulate her body temperature. The patient was hospitalized for syncope, when she passed out in her dad's arms. It was unknown that how many days was the hospital stay. The provider was the one who diagnosed her and did all the bloodwork and everything. Dysautonomia noted as It affected her whole autonomic system. When you look up dysautonomia with long term symptoms of COVID she had all of those symptoms. It was very hard for her to do anything she is so debilitated. 3 active infections noted as she did not know how long she has had them. She clarified that they started in 2021 after her Apr2021 dose of Pfizer Covid-19 Vaccine. She reported there are no treatment or medical interventions to report. All events for physician's office; for emergency room events were chronic pain; heart issues including syncope and blood pressure; can not regulate her body temperature.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201009808 Same patient and drug, different event separated in time;