both her hands were feeling pressure in her knuckles; redness in her hands; Itching; feeling headachy; feeling fluish; This is a spontaneous report from a contactable nurse.  A 61-year-old female patient received the first dose of bnt162b2 (BNT162B2; lot number EK5730), intramuscularly in the right upper arm on 16Dec2020 at 15:40 at 61-years-old at a single dose for COVID-19 immunization. The vaccination facility was a hospital. There were no additional vaccines administered on the same date of the Pfizer suspect or prior vaccinations within 4 weeks. Medical history included ongoing asthma (asthma began sometime in her 50s and was ongoing) from an unspecified date. The patient had no other adverse events to any other vaccines in the past and there was no relevant family medical history.  There were no concomitant medications. On 16Dec2020, the patient experienced: both her hands were feeling pressure in her knuckles, redness in her hands, itching. On an unspecified date in Dec2020, the patient experienced feeling headachy, feeling fluish. There was no visit to an emergency room or physician office. The clinical course was reported as follows: The patient was a nurse and she had a Pfizer lot number EK5730. The patient said she got the shot on 16Dec2020 at about 15:40 and when she got home both her hands were feeling pressure in her knuckles and they were red. Since then she had not stopped inching. The patient took cetirizine hydrochloride (ZYRTEC) and that made it stop enough; however, she could sleep but she still felt like she was itching all over. The patient clarified the pressure in her hands was primarily in her knuckles and then once that resolved she went to itching and feeling headachy. The patient clarified the redness was on her hands when she was having the pressure, her hands kind of got red. The patient reported the pressure in her knuckles had resolved completely and the redness in her hands and knuckles had resolved as well. The patient reported the itching began about an hour and a half after the injection and was ongoing, but it was not as bad since taking cetirizine hydrochloride twice. The patient reported the itching had improved. The patient did not have the NDC or expiration date. The patient did not know what dose was given. The card was all she had, and it just had the lot number and was to remind her to return for the next shot. The patient was calling Pfizer primarily about the itching and how she was feeling kind of "fluish", which she assumed was normal. The patient wanted to know, should she get the second shot, would she have a worse reaction to the second one. The patient needed to know because she was "miserable itching so bad and she thought the second one could be worse than the first." There was no relevant testing Therapeutic measures were taken as a result of both her hands were feeling pressure in her knuckles, redness in her hands, and itching The clinical outcome of the events: both her hands were feeling pressure in her knuckles, redness in her hands, was recovered on an unspecified date. The clinical outcome of the event, itching, was recovering. The clinical outcome of the event, feeling headachy and feeling fluish, was unknown.