my left knee became very swollen, stiff, and painful.; my left knee became very swollen, stiff, and painful.; my left knee became very swollen, stiff, and painful.; I think I have arthritis.; Both knees&thumbs were inflamed, cracking, stiff, painful; This is a spontaneous report received from a contactable consumer or other Non-health care professional. This case was split to capture events after first and second dose of vaccine. This is the second of two reports, reflecting events after the 2nd dose.  A 57-years-old non-pregnant female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/lot number: EW0175) via an unspecified route of administration in left arm on 28Apr2021 (at a age of 57-year-old) as dose 2, single for covid-19 immunization. Medical history includes Relapsing Remitting Multiple Sclerosis (RRMS), high cholesterol, high triglycerides, high LDL, depression (acute PTSD 21Dec2013). Patient had allergies to Sulfa (rash), Nickel (ears bleed) allergies to medications, food, or other products from an unknown date and unknown if ongoing. Prior to vaccination, the patient was not diagnosed with COVID-19. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Since the vaccination, the patient had not been tested positive for COVID-19. Patient previously received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/lot number: EW0162) via an unspecified route of administration in left arm on 09Apr2021 08:00 (at a age of 57-year-old) as dose 2, single for covid-19 immunization and experienced unable to walk without a limp, soreness at the injection site, Slept more, Left kneecap was very painful, Dry cough and tickle in my throat, tickle in my throat. Concomitant medications included ocrelizumab (OCREVUS) taken for relapsing-remitting multiple sclerosis, start and stop date were not reported, atorvastatin (ATORVASTATIN); citalopram (CITALOPRAM); calcium, ergocalciferol (VITAMIN D2 + CALCIUM [CALCIUM; ERGOCALCIF-EROL]); all taken for an unspecified indication, start and stop date were not reported. she received 1st dose of the Pfizer Covid-19 vaccine (left arm). 10Apr2021: she experienced soreness at the injection site & slept more than usual. 11Apr2021: when extending my left leg on my ottoman, it felt like her knee was hyperextended. Left kneecap was very painful, and she had to use a pillow under that knee routinely for a few weeks. she woke up between 2:30-3:00am for a few weeks w/ dry cough & tickle in her throat. This has since resolved. she was unable to walk without a limp after my 1st Pfizer dose due to pain in left knee. After her 2nd Pfizer Covid-19 vaccine on 28Apr2021, her left knee became very swollen, stiff, and painful. On 22-May she had a full-blown flair of whatever this is. Both knees & thumbs were inflamed, cracking, stiff, painful. she thinks she had arthritis. she had RRMS for 27+ years & she am on Ocrevus. My B-cells are now "0". she believes the Pfizer vaccine has triggered an inflammatory arthritic response in her body. she sees a rheumatologist on 02Jul2021. The patient underwent lab tests and procedures which included blood immunoglobulin g: positive on 26May2021 Semi QN, blood test: unknown on Blood test, lymphocyte count: 0 on unspecified date. The clinical outcome of not recovered.  No follow-up attempts are possible. No further information is expected.