feeling like I couldn't cool off enough; extremely nauseated; Tons of diarrhea; fever; hot flashes; tons of vomiting/thrown up; Some itchiness, esp. on backs of hands and legs; my throat / tongue-in-pharynx tingled and slowly, slightly swelled up; my throat / tongue-in-pharynx tingled and slowly, slightly swelled up; my throat / tongue-in-pharynx tingled and slowly, slightly swelled up; my throat / tongue-in-pharynx tingled and slowly, slightly swelled up; This is a spontaneous report from a contactable consumer.  A 38-years-old non-pregnant female patient received bnt162b2 (BNT162B2), via an unspecified route of administration, administered in Arm Left on 13Apr2021 14:00 (Batch/Lot number was not reported) (age at vaccination: 38 years) as DOSE NUMBER UNKNOWN, SINGLE for covid-19 immunisation. Medical history included severe apnea all night and day, cardiovascular issues, fibromyalgia, possible cushing's syndrome, autism, depression, PTSD, anxiety and crohn's in remission. The patient did not take other vaccine in four weeks. Concomitant medications included venlafaxine hydrochloride (EFFEXOR); diphenhydramine hydrochloride (BENADRYL); senna alexandrina leaf (SENNA [SENNA ALEXANDRINA LEAF]); melatonin (MELATONIN); omeprazole (OMEPRAZOLE). The patient previously took sulfa [sulfadiazine], macrobid [clarithromycin], abilify discmelt, geodon [ziprasidone hydrochloride] and Prozac, cloxapen [ampicillin trihydrate;cloxacillin sodium], and Lorazepam; all experienced drug hypersensitivity. On 13Apr2021, the patient experienced some itchiness, esp. on backs of hands and legs, my throat / tongue-in-pharynx tingled and slowly, slightly swelled up. On 14Apr2021 02:00, the patient experienced, feeling like i couldn't cool off enough, extremely nauseated, tons of diarrhea, fever, hot flashes, and tons of vomiting/thrown up. Clinical course included: on 13Apr2021, the patient experienced within 5 min of vaccination, her throat / tongue-in-pharynx tingled and slowly, slightly swelled up. She ended up staying a little more than an hour to make sure it wouldn't just keep on swelling more and more. Some itchiness, esp. on backs of hands and legs. Later in the evening, around 2am, she got extremely nauseated. Tons of diarrhea, fever and hot flashes, tons of vomiting, and felt like she couldn't cool off enough, even in a cold bath and with cold showers, sipping seltzer, etc. She felt a little better now that she thrown up and cooled off her body, but she was worried it will happen again or get worse. The patient was not tested positive for covid prior vaccination. The patient was tested positive for covid post vaccination. The patient underwent lab tests and procedures which included sars-cov-2 test negative on 30Mar2021. Therapeutic measures were taken as a result of some itchiness, especially on backs of hands and legs, my throat / tongue-in-pharynx tingled and slowly, slightly swelled up, feeling like i couldn't cool off enough, extremely nauseated, tons of diarrhea, fever, hot flashes, and tons of vomiting/thrown up with Benadryl x3 (1 just after vaccine, 2 at 2am). The outcome of the events was unknown.   No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected