First dose: Lightheaded and dizzy; First dose: Heart rate went from 99 beats per minute to 47 beats/min; First dose: Felt really cold; First dose: Flu symptoms; First dose: Chills; First dose: Nausea; She immediately felt flushed, dizzy/woozy; She immediately felt flushed, dizzy/woozy; This is a spontaneous report from a contactable consumer. A 66-years-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection. Batch/Lot Number: ER8727), dose 1 via an unspecified route of administration, administered in right arm on 24Mar2021 (at the age of 66-years-old) as DOSE 1, SINGLE for COVID-19 immunization. Medical history included cardiac pacemaker insertion (Pacemaker; Pacemaker patient had been on a medication after traumatic brain injury that over the long haul was not good for heart. Patient ended up with a pacemaker) from 2020 and ongoing. Craniocerebral injury (Traumatic brain injury; Reported that heart and breathing were affected by the brain stem injury) from 2020 and ongoing. Autonomic nervous system imbalance (Dysautonomia) from 2020 to an unknown date. Blood pressure abnormal (Keep blood pressure stable) from an unknown date and unknown if ongoing. Thyroid disorder (Thyroid) from an unknown date and unknown if ongoing. Eye operation (eyes operated on 3 times) from an unknown date and unknown if ongoing. Concomitant medications included hydrochlorothiazide 25 mg once daily (HYDROCHLOROTHIAZIDE) taken for blood pressure abnormal (Keep blood pressure stable) from 2014 and ongoing (Patient began taking hydrochlorothiazide after her traumatic brain injury due to dysautonomia); clonidine 0.1 mg once daily (CLONIDINE) began taken Clonidine about a year ago taken for blood pressure abnormal (Keep blood pressure stable) from an unspecified start date and ongoing; thiamazole 2.5 mg daily (METHIMAZOLE) started taking methimazole years ago, taken for thyroid disorder from an unspecified start date and ongoing. Patient had medications from her brain injury that takes on an as needed basis. Patient did not provide details of other medications. No prior Vaccinations (within 4 weeks). No adverse events following prior vaccinations. Family Medical History Relevant to adverse events reported that her sister that was vaccinated out in (city name) was having the same side effects as the caller. Caller reported that sister throat closed up and that sister was having all kinds of trouble. Patient never gets the flu vaccine and never gets the flu and her doctors are always annoyed that she would not take the shingles or flu vaccines. Patient was last vaccinated as a little kid. Vaccination facility type at hospital not at military facility. On 24Mar2021, the patient experienced very lightheaded and dizzy, heart rate went from 99 beats per minute to 47 beats/min, felt really cold, flu symptoms, chills, nausea, immediately felt flushed, dizzy/woozy. Patient stated that the heart reaction she experienced was not a normal side effect of the COVID-19 vaccine. It was reported that by the time that she got home on 24Mar2021 after about a half hour ride, patient was so cold. Patient woke up in the middle of the night on 24Mar2021 and could not sleep because of so cold patient had to put on a down parka. The flu symptoms were just awful for a few days and got progressively better. It was mentioned that, patient has been trying to stay hydrated and trying to let her immune system do its thing. The patient underwent lab tests and procedures which included heart rate: 99 beats per minute to 47 beats/min on 24Mar2021. Patient went to get the physician that was at the vaccination facility monitoring and doctor put an O2 monitor on the patient fingertip, physician watched the pulse monitor shoot up to 99 beats per minute and then drop to 47 beats per minute. Doctor then used her stethoscope to listen to the heart and the doctor reported that heard the pacemaker kick in. Patient had not been taking Tylenol or Ibuprofen. Cardiologist cleared her to get the second dose. The outcome of the events dizziness was recovered on Apr2021 (Duration of reaction/event: 8 Day), heart rate decreased (Duration of reaction/event: 0 Day) on 24Apr2021, Feeling cold, Influenza like illness, Chills and Nausea were recovered on 2021 (Duration of reaction/event: -82 Day) and while other events were recovering.   No follow-up attempts are possible. No further information is expected.