water in the lung; chest pain; enlarged heart/cardiomegaly; lethargic after 2-3 days; coughing really hard to the point of throwing up; stated that a little bit of blood came out from the coughing; shortness of breath; tight chest on the right side; infection; swallon lymph node; 2nd dose hurt; right arm was tight and swollen; right arm was tight and swollen; threw up few times; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PULMONARY OEDEMA (water in the lung), CHEST PAIN (chest pain) and CARDIOMEGALY (enlarged heart/cardiomegaly) in a 34-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 002F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included ETHINYLESTRADIOL, NORGESTIMATE (TRI-SPRINTEC) for Birth control, THYROID (ARMOUR THYROID) for Thyroid disorder, HYDROCHLOROTHIAZIDE, LOSARTAN POTASSIUM (LOSARTAN/HCTZ), FUROSEMIDE (LASIX [FUROSEMIDE]), POTASSIUM CHLORIDE and DOXAZOSIN MESILATE (CARDURA) for an unknown indication.    On 02-Sep-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced PULMONARY OEDEMA (water in the lung) (seriousness criterion medically significant), CHEST PAIN (chest pain) (seriousness criterion medically significant), CARDIOMEGALY (enlarged heart/cardiomegaly) (seriousness criterion medically significant), LETHARGY (lethargic after 2-3 days), COUGH (coughing really hard to the point of throwing up), HAEMOPTYSIS (stated that a little bit of blood came out from the coughing), DYSPNOEA (shortness of breath), CHEST DISCOMFORT (tight chest on the right side), VACCINATION SITE INFECTION (infection), LYMPHADENOPATHY (swollen lymph node), VACCINATION SITE PAIN (2nd dose hurt), VACCINATION SITE INDURATION (right arm was tight and swollen), VACCINATION SITE SWELLING (right arm was tight and swollen) and VOMITING (threw up few times). The patient was treated with DOXYCYCLINE at a dose of 1 dosage form. At the time of the report, PULMONARY OEDEMA (water in the lung), CHEST PAIN (chest pain), CARDIOMEGALY (enlarged heart/cardiomegaly), LETHARGY (lethargic after 2-3 days), COUGH (coughing really hard to the point of throwing up), HAEMOPTYSIS (stated that a little bit of blood came out from the coughing), DYSPNOEA (shortness of breath), CHEST DISCOMFORT (tight chest on the right side), VACCINATION SITE INFECTION (infection), LYMPHADENOPATHY (swollen lymph node), VACCINATION SITE PAIN (2nd dose hurt), VACCINATION SITE INDURATION (right arm was tight and swollen), VACCINATION SITE SWELLING (right arm was tight and swollen) and VOMITING (threw up few times) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Cardiomegaly: abnormal (abnormal) enlarged heart. In 2021, Chest X-ray: abnormal (abnormal) water on the lungs on the right lobe  side.         Lab data was not provided  After the 1st dose - The patient stated that after her 1st dose of moderna vaccine, she experienced a covid arm reaction and a lump. The patient stated that she did not even feel the needle go in.   After the 2nd dose - The patient reported 6 days later, she had to go to a ER walk in for chest pain but did not have hospital stays yet. The patient reported swollen lymph nodes as all lymph nodes were swollen on the right side and had an infection. The patient stated that the 2nd dose hurt as if something was in there. The chest X-ray revealed water on the lungs on the right lobe side, heart had cardiomegaly and an enlarged heart. The patient stated that the cat scan revealed that enlarged heart started to go down after the antibiotic (doxycycline).    The patient stated that she was lethargic after 2-3 days from receiving the 2nd dose and was coughing really hard to the point of throwing up. She stated that a little bit of blood came out from the coughing but coughed hard and threw up few times. She also reported experiencing shortness of breath, tight chest on the right side, right arm was tight and swollen.   The patient stated that she is glad that the heart is not enlarged now and does not have blood clots. The patient stated that she has a follow up with the pulmonologist and ID for lymph nodes. The patient is also has a future PET scan scheduled and stated that CAT scan found a node  Company Comment: This case concerns a 34 year old female with no relevant medical history who experienced serious unexpected event of pulmonary edema and nonserious unexpected event of cardiomegaly on unknown date after the second shot of the Moderan covid 19 vaccine. Rechallenge was not applicable. The benefit-risk relationship is not affected by this report.   This case was linked to MOD-2021-331411 (Patient Link).; Sender's Comments: This case concerns a 34 year old female with no relevant medical history who experienced serious unexpected event of pulmonary edema and nonserious unexpected event of cardiomegaly on unknown date after the second shot of the Moderan covid 19 vaccine. Rechallenge was not applicable. The benefit-risk relationship is not affected by this report.