prostate checked /getting an infection; mycosis fungoides T cell lymphoma; This spontaneous case was reported by a patient family member or friend and describes the occurrence of CUTANEOUS T-CELL LYMPHOMA (mycosis fungoides T cell lymphoma) and POST PROCEDURAL INFECTION (prostate checked /getting an infection) in a 59-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     It was reported that patient had no known allergies. The patient did not receive any other vaccines in the 4 weeks prior to COVID-19 vaccine.  The patient's past medical history included COVID-19 (Positive for COVID in MAY2020 but did not have any symptoms.) in May 2020 and Diuretic therapy (was on a diuretic prior to the vaccines). Family history included Bone disorder (She says her husband has a condition where his bones break a lot - this was inherited by his mother.) since an unknown date. Concurrent medical conditions included Asthma (has a history of asthma).   On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form and third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 31-Aug-2021, the patient experienced POST PROCEDURAL INFECTION (prostate checked /getting an infection) (seriousness criterion hospitalization). On an unknown date, the patient experienced CUTANEOUS T-CELL LYMPHOMA (mycosis fungoides T cell lymphoma) (seriousness criterion medically significant). The patient was hospitalized on 31-Aug-2021 due to POST PROCEDURAL INFECTION. At the time of the report, CUTANEOUS T-CELL LYMPHOMA (mycosis fungoides T cell lymphoma) had not resolved and POST PROCEDURAL INFECTION (prostate checked /getting an infection) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In May 2020, SARS-CoV-2 test: Positive. On an unknown date, Biopsy skin: diagnosed with mycosis fungoides T cell lymphoma.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered CUTANEOUS T-CELL LYMPHOMA (mycosis fungoides T cell lymphoma) to be related and POST PROCEDURAL INFECTION (prostate checked /getting an infection) to be not related.    No concomitant medications was reported.  Patient wife called and reported that both received 2 doses of the primary series of Moderna COVID-19 vaccine as well as a booster dose. She said that her husband had always had a mark on his back which they thought was a "birthmark." It looked like a birthmark and was just there, but never did anything. She said that after receiving the first dose itself, the "birthmark" started changing. This concerned them and they went to the doctor to get it checked. Patient also started to break out on his feet as well. When he got that checked, his doctor said that it looked like Lichen Planus. They didn't test him for anything at that time and it was just a diagnosis based on what the lesions looked like. After that, the mark and lesions started spreading all over his body. This time they went to a dermatologist for an opinion. She said "these things" were breaking out all over his body. The dermatologist biopsied his skin at the birthmark area. It took several weeks for the results to come back. The dermatologist called them stated that the patient had mycosis fungoides T cell lymphoma. She said that they were told that was a very rare form of cancer. Her husband started on a topical treatment at the cancer center. However, the topical treatment did not work, and the skin continued "to tear up." She said that they planned to go for different treatments. She again mentioned that this was a very rare cancer, and they were told that only about 200-300 people are diagnosed with this every year. As such, they were told that there was no cure for it, but they can try to treat the patient to the best of their abilities. The disease has rapidly progressed, to the point where the patient was already on stage 3 of the cancer. It has spread fast. Due to this the doctors can only treat him and make him feel comfortable as it has advanced so much. They then sat down and asked the doctor that the patient has never had any skin issues whatsoever, not even pimples as a teenager. Then what could have caused this? Caller stated that it was only after taking the vaccine that his issues started. The doctor explained to them how the vaccine worked and that the patient may have had the cancer dormant in the body and it would have come up at some time, however, the vaccine may have speed up the process. She said that after hearing that, she has been very angry that her husband took the vaccine. She said that may come naturally later than at this time because this has disrupted the patient's life. He cannot work anymore, and it's just changed him. He doesn't even look the same anymore. She said that she had a real serious problem. She affirmed that she was not an anti-vaccine as she has received vaccines as a kid. However, she does feel like this vaccine was rushed to give to people. If she had known that the immune system gets a jump start on diseases due to the vaccine, they would not have taken it at all. She said that her husband wanted to enjoy his retirement. He had to apply for social security disability. She wanted to complain about this what has happened to her husband. She said that she wanted someone to compensate them for what her husband has had to endure. She doesn't know if it's going to be Moderna or the government, but somebody does need to do that. He couldn't finish his job and had to stop unexpectedly and had to go on social security disability. She also said that her husband must go for counseling because of all the issues he was experiencing. She mentioned that she has seen similar cases being talked about online where people have experienced the same issues as her husband. Unrelated to the above issue, she said that her husband was admitted to the hospital on 31-AUG-2021 because he went to get his prostate checked and the doctor did not prescribe prophylactic antibiotics to him prior to that due to which he ended up getting an infection and was admitted to the hospital that was where the first lesions on his skin were noticed by a doctor.  Company Comment: This is a spontaneous case concerning a 59-year-old, male patient with no relevant medical history, who experienced the unexpected serious (medically significant) event of Cutaneous T-cell lymphoma. The event occurred after the administration of the first dose of mRNA-1273 vaccine, latency is unknown. Reporter states that the patient always had a type of birthmark in his back however, after the administration of the first dose, the lesion began to spread all over his body. A biopsy was performed and mycosis fungoides T cell lymphoma was diagnosed. Patient is now in stage 3 of the cancer. Dermatologists stated that the vaccine could have sped up the process. Patient received 3 doses of mRNA-1273 vaccine. It is also reported that he had been admitted to hospital after an infection secondary to a prostate check which is not considered related to vaccination. More information is requested for this case. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning a 59-year-old, male patient with no relevant medical history, who experienced the unexpected serious (medically significant) event of Cutaneous T-cell lymphoma. The event occurred after the administration of the first dose of mRNA-1273 vaccine, latency is unknown. Reporter states that the patient always had a type of birthmark in his back however, after the administration of the first dose, the lesion began to spread all over his body. A biopsy was performed and mycosis fungoides T cell lymphoma was diagnosed. Patient is now in stage 3 of the cancer. Dermatologists stated that the vaccine could have sped up the process. Patient received 3 doses of mRNA-1273 vaccine. It is also reported that he had been admitted to hospital after an infection secondary to a prostate check which is not considered related to vaccination. More information is requested for this case. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.