decreased fluid in legs; feeling hot and then cold; food not tasting good whenever eating; not feeling good described as lack of energy; more pronounced lower back and knee pain and no energy when walking; shortness of breath when moving or exerting; worsened asthma described as cough coming and going; Lack of appetite; perspiring or sweating; Nausea; Knee pain and pain between shoulder blades; Low-grade fever; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of FEELING HOT (feeling hot and then cold), TASTE DISORDER (food not tasting good whenever eating), ASTHENIA (not feeling good described as lack of energy), BACK PAIN (more pronounced lower back and knee pain and no energy when walking) and DYSPNOEA (shortness of breath when moving or exerting) in a 79-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Allergic asthma (with a bronchial asthmatic cough), Lymphedema, Back pain (lower) and Knee pain. Concomitant products included CANDESARTAN for Blood pressure, NAPHAZOLINE HYDROCHLORIDE (EYE DROPS [NAPHAZOLINE HYDROCHLORIDE]) for Glaucoma, TAPENTADOL HYDROCHLORIDE (NUCYNTA) and TAPENTADOL HYDROCHLORIDE (NUCYNTA ER) for Pain, LEVOTHYROXINE for Thyroid disorder NOS, RABEPRAZOLE SODIUM (RABEPRAZOLE EC), PRAMIPEXOLE, PARACETAMOL (TYLENOL), XYLOMETAZOLINE HYDROCHLORIDE (NASAL SPRAY II), CIMETIDINE, MIRABEGRON (MYRBETRIQ), OXYBUTYNIN, MULTIVITAMIN [VITAMINS NOS], MILK THISTLE [SILYBUM MARIANUM], CARMELLOSE SODIUM (THERATEARS), COENZYME Q10 [UBIDECARENONE], VITAMIN B COMPLEX, VITAMIN D NOS and TURMERIC [CURCUMA LONGA RHIZOME] for an unknown indication.   On 06-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 03-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced FEELING HOT (feeling hot and then cold), TASTE DISORDER (food not tasting good whenever eating), ASTHENIA (not feeling good described as lack of energy), BACK PAIN (more pronounced lower back and knee pain and no energy when walking), DYSPNOEA (shortness of breath when moving or exerting), COUGH (worsened asthma described as cough coming and going), DECREASED APPETITE (Lack of appetite), HYPERHIDROSIS (perspiring or sweating), NAUSEA (Nausea), ARTHRALGIA (Knee pain and pain between shoulder blades), PYREXIA (Low-grade fever) and OEDEMA (decreased fluid in legs). At the time of the report, FEELING HOT (feeling hot and then cold), TASTE DISORDER (food not tasting good whenever eating), HYPERHIDROSIS (perspiring or sweating) and NAUSEA (Nausea) had not resolved and ASTHENIA (not feeling good described as lack of energy), BACK PAIN (more pronounced lower back and knee pain and no energy when walking), DYSPNOEA (shortness of breath when moving or exerting), COUGH (worsened asthma described as cough coming and going), DECREASED APPETITE (Lack of appetite), ARTHRALGIA (Knee pain and pain between shoulder blades), PYREXIA (Low-grade fever) and OEDEMA (decreased fluid in legs) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 09-Mar-2021, Electrocardiogram: positive (Positive) heart attack and Covid-19 infection were ruled out by the ER physician.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown Route), the reporter did not provide any causality assessments.   She tried and failed ondansetron 4 mg therapy for the nausea.   This case was linked to MOD-2021-041179 (Patient Link).