Felt like was having a MS Flare; Migraine; A lot of spasticity; Massive Covid Leg, rash about the size of hand at injection site on left thigh.; Couldn't get out of bed without help; Covid leg: Patient reported that there is an area on the affected leg about the size of a dollar bill that was red and sore; Covid leg: Patient reported that there is an area on the affected leg about the size of a dollar bill that was red and sore; leg is just a little sore; BNT162B2 received in leg; This is a spontaneous report from a contactable consumer (patient). A 61-year-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Lot Number: ER8727) via an unspecified route of administration on 26Mar2021 at 08:30 as single dose in left thigh for COVID-19 immunisation at state ran convention centre. Medical history included multiple sclerosis from 02Apr1999 and ongoing. Concomitant medication was not reported. The patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Lot Number: EN6205) on 05Mar2021 (at age of 61-year-old) in right thigh for COVID-19 immunisation. Patient stated you know that thing that they call Covid arm, except it's Covid leg because that's where she had the Covid-19 vaccine injection. Patient reported that she had multiple sclerosis. Patient reported that she had no reaction whatsoever to the first dose of the Covid-19 vaccine and it was a total non-issue. Patient reported that she opted to receive the Covid-19 vaccine in her leg because she has absolutely zero use of her legs and needed full use of her arms. Neurologist said it was ok for her to receive the vaccine in her leg. Saturday Morning she woke up with a migraine and a lot of spasticity on 27Mar2021. For lot of spasticity and patient took Baclofen. Patient reported that she couldn't get out of bed without help on 27Mar2021 from her husband. Patient reported that needing assistance to get out of bed was more than her usual Multiple Sclerosis dysfunction. patient reported that her neurologist stated that the side effects she was experiencing were most likely a reaction to the Covid-19 vaccine. Patient reported that she kind of expected to have a reaction to the Covid-19 vaccine. Patient reported that her neurologist gave her a refill of her migraine medicine, sumatriptan nasal spray. Covid leg: Patient reported that there is an area on the affected leg about the size of a dollar bill that was red and sore on 27Mar2021. Patient reported that it was uncomfortable to sleep on the side of the affected leg. Patient reported that she doesn't really have an appreciable use of her legs anyway so it's not like the covid leg has resulted in decreased function, but the affected leg is just a little sore on 27Mar2021 and uncomfortable. Patient reported that her migraine was gone. Patient stated that she figured the other symptoms felt like a Multiple Sclerosis exacerbation. Patient reported that her doctor's office reassured that her symptoms were not an exacerbation of Multiple Sclerosis. Massive Covid Leg: Rash about the size of her hand at the injection site in her left thigh on 27Mar2021. Started on Saturday and was getting bigger. Migraine: Started on Saturday. Patient took Generic Imitrex Nasal Spray, she believed was called Sumatriptan. Said it was prescribed as needed with a max of 2 times a day use. Migraine lasted for a couple of hours before she recovered completely from it that same day around noon. MS Flare on 27Mar2021: Stated she felt like she was having one starting Saturday. She couldn't get out of bed without help on Saturday which was worse than normal for her in regard to a MS Flare. Her Neurologist said it wasn't a true flare. patient stated she was getting better. Temperature: States she took her temperature and had no fever. Says she tends to be below normal temperature and usually was around 97.5 degrees. When she took her temperature Saturday she was 98.3 degrees on 27Mar2021. The outcome of event multiple sclerosis flare was recovering, migraine recovered on 27Mar2021, for spasticity, weakness, leg pain, vaccine administered at inappropriate site was unknown and for remaining events was not recovered.   No follow-up attempts are possible. No further information is expected.