Blood work that showed elevated clotting factors and CRP; clotting factor specifically called factor 8; This spontaneous case was reported by a consumer and describes the occurrence of ABNORMAL CLOTTING FACTOR (Blood work that showed elevated clotting factors and CRP; clotting factor specifically called factor 8) in a female patient of an unknown age who received mRNA-1273.815 (SPIKEVAX 2023-2024) for COVID-19 prophylaxis.     Previously administered products included for COVID-19 prophylaxis: Pfizer (Dose 1, Lot number- EL0142) on 05-Jan-2021, Pfizer (Dose 2, Lot number- EL3248) on 26-Jan-2021, Moderna COVID-19 vaccine (Dose 3, Lot number- 051F21A) on 04-Nov-2021, Pfizer (Dose 4, Lot number- GH9702) on 17-Sep-2022, Pfizer (Dose 4, Lot number- GH9702) on 17-Sep-2022, Pfizer (Dose 4, Lot number- GH9702) on 17-Sep-2022, Pfizer (Dose 4 and Lot number- GH9702) on 17-Sep-2022. Past adverse reactions to the above products included Cerebral venous sinus thrombosis with Pfizer; Dizziness with Pfizer; No adverse reaction with Moderna COVID-19 vaccine, Pfizer and Pfizer; Transverse sinus thrombosis with Pfizer; and Vertigo with Pfizer. Concurrent medical conditions included Migraine. Concomitant products included BUDESONIDE, FORMOTEROL FUMARATE (SYMBICORT) for Allergy, UBROGEPANT (UBRELVY), BOTULINUM TOXIN TYPE A (BOTOX), DICLOFENAC POTASSIUM (CAMBIA) and TOPIRAMATE (TROKENDI XR) for Migraine.    On 19-Oct-2023, the patient received fifth dose of mRNA-1273.815 (SPIKEVAX 2023-2024) (Intramuscular use) 1 dosage form. On 23-Oct-2023,  after starting mRNA-1273.815 (SPIKEVAX 2023-2024), the patient experienced ABNORMAL CLOTTING FACTOR (Blood work that showed elevated clotting factors and CRP; clotting factor specifically called factor 8). The patient was treated with ACETYLSALICYLIC ACID (BABY ASPIRIN) at a dose of 81 milligram once a day. At the time of the report, ABNORMAL CLOTTING FACTOR (Blood work that showed elevated clotting factors and CRP; clotting factor specifically called factor 8) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 23-Oct-2023, Blood test: showed elevated clotting factors, The clotting factor specifically called factor 8. On 23-Oct-2023, C-reactive protein: elevated. On an unknown date, Angiogram cerebral: blood is flowing through the sinus. On an unknown date, Venogram: blood is flowing through the sinus.         Consumer stated, so back in July consumer stopping reporting, but consumer had an episode of almost like extreme vertigo, very extreme she could not stand and was using the wall to hold herself up. This happened two or three times maybe three or more times in about a ten-day period, in July and then in august and September patient had migraine and suffer from migraine. Patient had migraine but could not control of medication and should add this, patient never had dizziness with her migraine, that's never been an issue, vertigo never been an issue with her migraine but after these episodes in July patient had this migraine that could not be control by medicine. It was the combination of these events that confirms her neurologist to call for a brain MRI. Patient did that on October 18th. So, the last vaccine patient had before October 18th was Pfizer. That's why patient was calling. The very next day patient had got the Covid vaccine Moderna and four days later patient had blood work that showed elevated clotting factors and CRP. So, patient cannot tell you that which vaccine is causing what, but patient think that it should be reported.  Consumer stated that she stops reporting episodes of extreme vertigo like phenomenon in July. Patient had about 3 or 4 episodes in about 7 to 10 days period in July and then in August and in September patient had migraine that could not control with medication which is unusual for her. Patient usually can control it. When probed to clarify the name of the medication (Migraine) and also that the medication was not working, consumer stated, only of those occasion it did not work. It was unusual that it would not work. Patient had gone years and been fine with the medication she had. Consumer stated, calling for recanalization of cerebral venous sinus thrombosis, so it was resolving. Patient thought that was what they were saying. Patient had the brain MRI on October 18th.