Report received from a R.N. (who is also the patient) on 20-NOV-2009.  The 55 year-old female patient received H1N1 vaccination with lot number 00349611A, exp date 30-Jun-2010 for immunization on 19-Nov-2009 at 10:15 AM.  The patient had a medical history of allergies to lots of things and so at the time of vaccination, requested the preservative-free, latex-free vaccine.  On 19-Nov-2009, 15-20 minutes after H1N1 vaccination, the patient felt flush, very warm, and the sensation of feeling closed in.  Her face was red and blotchy.  She felt woozy.  At 11:00 AM, she took 25 mg Benadryl Clear for a red, hot face.  At 12:15 PM, her eyes and mouth/back of throat were itchy.  There were no noticeable hives.  She took another 25 mg dose of Benadryl Clear.  Three hours after the second dose of Benadryl, her eyes and the back of her throat felt itchy.  She had mild flat, firm, reddened areas on her arm.  Her arms were not itchy.  Later she felt chills and headache.  She had tachycardia and palpitations.  At 6:00 PM the nurse called her physician who advised her to take 50 mg Benadryl.  By 9:00 PM, her chest felt like it was in a vice grip.  There was no wheezing or bronchitis.  She felt like her breathing was "up high" in her lungs, a squeezing tightness in chest from mid-sternum to clavicle in the front and back, and bronchitis sensation.  At 9:30 PM, she presented to the emergency room per physician recommendation.  Her Oxygen saturations were fine.  She was tachycardic, had elevated BP, blotches on her arms, and facial redness.  She was placed on a heart monitor in the ER and her BP was monitored as well.  By 11:00 PM, her eyes and back of throat felt itchy.  The tightness in her chest was the same.  At 11:10 PM, she was administered 50 mg IV Benadryl.  Within 15 minutes, the itchiness in her eyes and throat subsided.  The tightness in her chest area decreased.  The patient had been seen by her family physician and cardiologist.  There was a question if her palpitations, tachycardia, and blood pressure were Benadryl induced.  Atarax 10 mg x 2 days was ordered instead of Benadryl and she was encouraged to drink fluids.  At the time of reporting, the patient had no itching or hives and everything was subsiding.  She felt "whipped" and "wiped out" and hoarseness.  She had a few episodes of palpitations and tachycardia (heart rate of 110).  The patient reported her heart rate had been in the 160s the day before.  The patient has reported the events to the CDC.  Follow-up information was received on 24-Nov-2009: The physician called to report the patient has an allergy to neomycin and polymyxin which are listed as contraindications for the vaccine.  The physician asserted the adverse events were part of an allergic reaction, which is expected for persons with the aforementioned allergies.  He considered the causality to be highly probable.  Follow-up information received 25-Nov-2009 from the nurse at MD office who indicated the patient was on the road to recovery and her overall symptoms have improved.  Follow-up information received on 14-Dec-2009 from the physician's office.  The patient reported to the physician's office that she is fully recovered.  No further information is expected.  Information derived from this AE report does not change the safety profile of the product.