All my Parkinson's symptoms were magnified incredibly/a lot of motor symptoms with the Parkinson's; I couldn't get out of chair/I was falling over when I managed to get out of chair; Lot of energy; freezing gait, dyskinesia, and micrographia, just to name 3 symptoms, were gone for 5 days. / it's something magical / something with the mRNA vaccine made her Parkinson's symptoms disappear; I was falling over when I managed to get out of chair; This spontaneous case was reported by a consumer and describes the occurrence of PARKINSON'S DISEASE (All my Parkinson's symptoms were magnified incredibly/a lot of motor symptoms with the Parkinson's) in a 69-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 030L20A and 002B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Parkinson's disease since February 2021. Concomitant products included ROSUVASTATIN and DOXYCYCLINE for an unknown indication.   On 14-Mar-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 23-Sep-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 23-Sep-2021, the patient experienced PARKINSON'S DISEASE (All my Parkinson's symptoms were magnified incredibly/a lot of motor symptoms with the Parkinson's) (seriousness criterion medically significant), MOBILITY DECREASED (I couldn't get out of chair/I was falling over when I managed to get out of chair) and ENERGY INCREASED (Lot of energy). 23-Sep-2021, the patient experienced THERAPEUTIC RESPONSE UNEXPECTED (freezing gait, dyskinesia, and micrographia, just to name 3 symptoms, were gone for 5 days. / it's something magical / something with the mRNA vaccine made her Parkinson's symptoms disappear) and FALL (I was falling over when I managed to get out of chair). On 23-Sep-2021, MOBILITY DECREASED (I couldn't get out of chair/I was falling over when I managed to get out of chair) and FALL (I was falling over when I managed to get out of chair) had resolved. On 28-Sep-2021, ENERGY INCREASED (Lot of energy) had resolved. At the time of the report, PARKINSON'S DISEASE (All my Parkinson's symptoms were magnified incredibly/a lot of motor symptoms with the Parkinson's) and THERAPEUTIC RESPONSE UNEXPECTED (freezing gait, dyskinesia, and micrographia, just to name 3 symptoms, were gone for 5 days. / it's something magical / something with the mRNA vaccine made her Parkinson's symptoms disappear) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment medication were not reported. Patient says that within 9 hours of receiving the vaccine, patient experienced 17 hours of hell. Patient had a history of Parkinson's and patient states that all her symptoms of Parkinson's were incredibly magnified. Patient says that patient couldn't even get out of her chair. When patient did manage to get out of the chair after a dozen or so attempts, patient ended up falling over. However, after 17 hours of experiencing this, patient woke up and felt like a new person. Patient says that her Parkinson's symptoms had disappeared. Patient has a lot of motor symptoms with the Parkinson's and patient said that her freezing gait, dyskinesia, and micrographia, just to name 3 symptoms, were gone for 5 days. Patient says that at this point her symptoms are starting to return. Patient also stated that patient got a lot of energy from this that patient hasn't experienced for a year. Patient called it a magical feeling. Patient says that patient was diagnosed with Parkinson's in FEB2021 and has been prescribed medication for it, but hasn't started taking it yet. Patient also says that something with the mRNA vaccine made her Parkinson's symptoms disappear.   This case of unexpected therapeutic benefit concerning a 69-year-old female patient with reported relevant medical history of Parkinson's disease, who experienced the unexpected event of Parkinson's disease aggravated. Unexpected therapeutic benefit occureed 17 hours after vaccine administration with disappearance pf Parkinson's symptoms for 5 days. Parkinson's disease aggravated onset was same day after the third dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was not unknown as there's no information available about the first or second dose. Causality assessment for the reported event was not provided by the reporter. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report. Event is confounded by the patient's underlying medical history; Sender's Comments: This case of unexpected therapeutic benefit concerning a 69-year-old female patient with reported relevant medical history of Parkinson's disease, who experienced the unexpected event of Parkinson's disease aggravated. Unexpected therapeutic benefit occureed 17 hours after vaccine administration with disappearance pf Parkinson's symptoms for 5 days. Parkinson's disease aggravated onset was same day after the third dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was not unknown as there's no information available about the first or second dose. Causality assessment for the reported event was not provided by the reporter. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report. Event is confounded by the patient's underlying medical history.