shortness of breath, constricted breathing, tightness, couldn't get enough air in, and was thought to be an asthmatic reaction; shortness of breath, constricted breathing, tightness, couldn't get enough air in, and was thought to be an asthmatic reaction; shortness of breath, constricted breathing, tightness, couldn't get enough air in, and was thought to be an asthmatic reaction; This is a spontaneous report from a contactable consumer (patient's sister). A 46-year-old female patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; lot number and expiration date not reported), via an unspecified route of administration on 22Jul2021 17:11 (at the age of 46-years-old) at dose 1, single for COVID-19 immunization. Medical history included asthma, ongoing severe nut allergy, and allergies. Concomitant medication included montelukast sodium (SINGULAIR) for asthma and allergies. The patient previously took epinephrine (Epi-Pen) for allergies. The patient has no prior vaccinations (within 4 weeks). On 22Jul2021 21:11, 4 hours after the vaccination, the patient had reactions to the vaccine which included shortness of breath, constricted breathing, tightness, couldn't get enough air in, and was thought to be an asthmatic reaction. The night the reactions happened, it was reported that the patient messaged everyone saying that she loved them because she was unsure if she was going to wake up. The patient messaged her doctor and the doctor told her that they did not have any recommendations for her and that she needed to speak with an allergist. The patient was put in contact with an allergist and the patient was told that the allergist couldn't help and that she needed to speak with her primary care doctor. The patient felt that no one can help her and that she was left to make this decision on her own. The patient has been told that maybe she should take an antihistamine prior to her second dose and have an Epi-Pen with her just n case. The patient's sister stated that it was a scary thing and compared the patient's experience to her being allergic to peanuts and sticking her head in a jar of peanuts but will be okay since if a reaction occurred, Epi-Pen will be used. The patient was trying to determine if she should receive the second dose of the vaccine or not due to the reactions she experienced after the first dose. The patient would like to have the second dose because she was high risk due to her and her husband's job and that they are caring for their 95-year-old grandmother and wanted to keep her safe. The patient's sister was asking if the patient can take antihistamines or Tylenol before or after the dose. They thought of taking prednisone before the dose but the doctor explained that this would be a bad idea, so they are not going to take it. The reporter took a long time to convince the patient to get the shot. The patient was concerned about getting the second shot due to the terrible reactions happened after the first dose vaccination. It took a couple of days before the patient felt okay and before the patient's breathing became better. The patient was afraid the night the reactions occurred because she thought that she would not wake up in the next morning, it was that bad. But the next morning, the patient felt better. She had this feeling at least until she went to bed and through the night. For the next few days, she took it easy; she would just sit and read and do no exercising. After that she was not afraid anymore. The patient took two Benadryl, 3 puffs of the Albuterol inhaler, and two applications of Vapor Rub under her nose as treatments for the events. The events did not result to emergency room visit, however, the events required physician office visit. The patient went to the doctor, but she was not admitted to the hospital. The patient was thinking of driving directly to her doctor's office and sitting in the parking lot there after her second dose. The patient lives in a rural area and it takes 30 minutes just to get an ambulance there. The patient was still unsure if she would get the second dose or not. Outcome of the events was recovering.  The lot number for the vaccine, BNT162B2, was not provided and will be requested during follow up.