Polymyalgia rheumatica; Diarrhea; tired; very weak; Anemic; Fever; aching; This is a spontaneous report from a contactable consumer (patient). A 72-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), second dose at the age of 72-years-old, via an unspecified route of administration administered in arm right (reported as right shoulder) on 19Mar2021 (Batch/Lot Number: EP7534) as 2nd dose single for covid-19 immunisation. Medical history included multiple sclerosis from 31Aug1989 to an unknown date (had it for 30 years). The patient's concomitant medication included prednisone for multiple sclerosis from an unspecified date and ongoing. The patient received the first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE) at the age of 71-years-old administered on right shoulder on 26Feb2021 (lot number: EN6205) for covid-19 immunisation. The patient wanted to ask about any side effects with the COVID shot that she had. She mean it happened after she had the first shot a little bit and then after second shot it was really bad. She started to have to take Tylenol because it was really aching which she understood that for the first shot and it kind of settled down. But then after the second shot two days later on 21Mar2021, she did have that diarrhea and she know that that was something that they told you about. But now she have really gotten even it is almost two months now, very tired, very weak on an unspecified date in 2021. They did do some blood work on her. She was anemic which she wasn't back in January when they did some blood work and she do have MS (Multiple sclerosis). So if she get a small, just a small lump, fever it really knocks her for a loop and she have just been having fevers like every day from an unspecified date in 2021. It will go up to like 99 six like 101 with normal person. Then in the morning, it will be down but it will gradually go back up. But this is all to inspired from you know since she got the shot and she do have MS and she don't know whether it might have exacerbated her MS. They did put me on some Prednisone (treatment) for multiple sclerosis and they did put her on Prednisone to see if that would help that. She have already been on it about a week now. The patient further reported she started to be very tired and needed to take Tylenol to somewhat get around to keep her temperature down. It started to go up then and then it kept on increasing, for that she had to take more Tylenol (further not clarified) and it is just been like that even after the second shot and besides that having the temperature also. She meant that's why she was taking Tylenol trying to get the temperature and the aching down. The aching she can take, but she can't take the temperature. All she take is Tylenol (treatment) to keep the temperature down, take like a multivitamin (further not clarified) she was also taking Prednisone right now because they are trying to see if that will help the weakness and everything else. But she have only been on like 10 days. Lab works were done because when she started having the weakness and everything, she went in to her regular doctor. She did some lab work. It showed that she was anemic and that her SED rate was up and then she went to a rheumatologist and he did diagnosed he and this is the another reason why she was taking prednisone (treatment) that she have polymyalgia rheumatica. She further reported that what she talked to the doctor on the phone this is her regular primary care she told her that she was anemic. She don't know how low it was, but she was anemic and then also the SED rate was 57 which was indicative of possibly having polymyalgia. The patient underwent lab tests and procedures which included blood creatine phosphokinase: 30, blood uric acid: 3.6, complement factor c3: 137, complement factor c4: 22, red blood cell sedimentation rate increased: 57 (sed rate was up)  which was indicative of possibly having polymyalgia whatever, rheumatoid factor: negative on an unspecified date in 2021. Therapeutic measures were taken as a result of polymyalgia rheumatica, aching, diarrhea, tired, very weak, fever which included prednisone and Tylenol. The outcome of polymyalgia rheumatica and anemic was unknown, while the patient did not recover from the other events.