Drug ineffective; Tested positive for Covid again; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 72-year-old female patient received BNT162b2 (BNT162B2 NOS), as dose number unknown, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "COVID-19" (unspecified if ongoing). The patient's concomitant medications were not reported. The following information was reported: DRUG INEFFECTIVE (medically significant) with onset 21Feb2023, outcome "unknown"; COVID-19 (medically significant) with onset 21Feb2023, outcome "unknown", described as "Tested positive for Covid again". The patient underwent the following laboratory tests and procedures: SARS-CoV-2 test: (08Feb2023) Negative; (15Feb2023) Negative; (16Feb2023) Negative; (21Feb2023) Positive. Therapeutic measures were taken as a result of drug ineffective, covid-19. Clinical Course: The patient was tested positive for COVID again on 21Feb2023. Information confirmed as provided. Patient had to go another period of isolating. Patient mentioned to go for testing in the afternoon. Doctor recommended it. Patient stated that they chose Pfizer. Stated that she chose Pfizer for her vaccines and was a fan of Pfizer again. Main reason patient chose Pfizer was because her husband had underlying conditions and this would help to lower the possibility of transmission to him. Thought that patient was 72 and would take it and a couple of friends, others. The company needed to figure out what was not working right. Maybe they need an extra day or start a day later and tweak it, so it did not happen often. Was grossly underreported. The patient tested positive for Covid again: Tested positive again on 21Feb2023. Tested negative on 08Feb2023 day which amazed her. Tested negative on 15Feb2023 and 16Feb2023. Tested on today because her husband got COVID and he was in his most contagious days thought it was better to test again because now she was more susceptible. Again tested negative on 15Feb2023 and 16Feb2023. Felt that was the data point and she did not just test negative on 08Feb2023 but the other two days 15Feb2023 and 16Feb2023. Happened was she would say she was on her way to recovering but still had the cough, the cough had not left. Attempted to capture the outcome but reporter unable to provide. Patient's cough (from unknown date) and congestion (from 18Feb2023) was reported as worsened. Patient had no other condition provided and investigations were done. Patient was on her way to recovering but still had the cough the cough had not left. Cough happened a couple of days into having Covid 05Feb2023 or 06Feb2023. Cough has worsened. Treatment: Took a dose of cough medicine last night. Congested: On 18Feb2023, she started to be congested. Was still congested. Has worsened. Treatment: Sudafed.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received. Sender's Comments: Linked Report(s): US-PFIZER INC-202300078047 same patient, different suspect and event;US-PFIZER INC-202300078468 same reporter, different drug, event and patient;US-PFIZER INC-202300078614 same reporter, different drug, event and patient;