yeast infection was very extreme, there was a lot bleeding.; noticed some thrush in my throat starting to happen as well; Oral yeast infection/Oral Fungal infection; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 32-year-old female patient (not pregnant) received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 18Jul2023 at 16:15 as dose 4 (booster), single (Lot number: GK0928) at the age of 32 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "POTS" (unspecified if ongoing); "inappropriate sinus tachycardia" (unspecified if ongoing); "MCAS" (unspecified if ongoing); "hypermobile EDS" (unspecified if ongoing); "sleep apnea" (unspecified if ongoing); "asthma" (unspecified if ongoing); "IBS" (unspecified if ongoing); "arthritis" (unspecified if ongoing); "Known allergies: peanuts" (unspecified if ongoing); "Known allergies: cashews" (unspecified if ongoing); "oral thrush, which I have had before" (unspecified if ongoing); "immune compromised" (unspecified if ongoing). The patient took concomitant medications. Past drug history included: Morphine, reaction(s): "Known allergies: morphine"; Fluoroquinolones, reaction(s): "Known allergies: fluoroquinolones". Vaccination history included: Covid-19 vaccine (Dose 1; Manufacturer Unknown), for COVID-19 immunization; Covid-19 vaccine (Dose 2; Manufacturer Unknown), for COVID-19 immunization; Bnt162b2;bnt162b2 omi ba.4-5 (DOSE 3 (BOOSTER), SINGLE), administration date: Sep2022, for COVID-19 immunization, reaction(s): "I am severely ill but both times taking the bivalent booster has resulted in mild to severe fungal infections for me", "oral thrush". The following information was reported: ORAL FUNGAL INFECTION (non-serious) with onset 22Jul2023 at 20:00, outcome "recovering", described as "Oral yeast infection/Oral Fungal infection"; OROPHARYNGEAL CANDIDIASIS (non-serious) with onset 22Jul2023 at 20:00, outcome "recovering", described as "noticed some thrush in my throat starting to happen as well"; PHARYNGEAL HAEMORRHAGE (medically significant) with onset 22Jul2023 at 20:00, outcome "recovering", described as "yeast infection was very extreme, there was a lot bleeding.". The events "yeast infection was very extreme, there was a lot bleeding.", "noticed some thrush in my throat starting to happen as well" and "oral yeast infection/oral fungal infection" required physician office visit. Therapeutic measures were taken as a result of pharyngeal haemorrhage, oropharyngeal candidiasis, oral fungal infection. Clinical course: Patient was  immune compromised so she got a second bivalent booster this month because she wanted to go to a dentist appointment, but this time instead of oral thrush she developed a yeast infection. It is the first yeast infection she have ever had in her adult life, and it developed 3 days after taking the vaccine. Patient also noticed some thrush in her throat starting to happen as well. The yeast infection was very extreme, there was a lot of swelling, pain, and bleeding. Patient did not normally have fungus reactions like this unless she severely ill but both times taking the bivalent booster has resulted in mild to severe fungal infections for her. patient contacted to her doctor. both times and she offered to prescribe fluconazole for the yeast infection but she had already taken Monistat over the counter and it started to recede by the time she offered.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300261671 as same reporter/patient/drug, different dose/event;