Yesterday her joint pain started, and her left knee hurt really bad. Her elbows hurt so bad; dizziness; chills; fever; Nausea; This is a spontaneous report from a contactable Nurse via Pfizer sponsored program. A 39-year-old nurse female (patient) received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Lot Number: EM6200), via intramuscular route of administration in the right deltoid region on 23 Feb 2021 between 14:00 and 15:00 as single for COVID-19 immunisation. The patient historical vaccine included first dose of BNT162B2 on 02 Feb 2021 for COVID-19 immunisation. The patient's medical history included Premature ventricular contractions, Hypertension, Cancer, Breast cancer, Colon cancer, Congenital cardiac hypertrophy and she had a hysterectomy after four days, she developed a pulmonary embolism. The patient's past medication history included metoprolol. Concomitant medications were not reported. On 24Feb2021, She went to work the next day. She started her shift, and then in the afternoon about 8:30PM, she started getting chills. Her co worker measured her temperature, and it was 100.5 degrees. She went home, and by the time she got home her temperature was 101.5 degrees. Later on that night, her temperature got up to 103 degrees. Her temperature did get lower with Tylenol. On an unknown date in Feb2021, the patient experienced nausea. She was wondering if maybe someone else was also feeling the same way. She felt nauseous four of five days after receiving the second dose of the covid vaccine. Recently, she had became more nauseous. On 28Apr2021, the patient experienced dizziness after a full day of work. It was reported that she felt like she got punched in the face, melting and everything around her was moving because she was so dizzy. She took a step backward and felt like something was hitting her. She went to emergency department and the physician did a CT of her head, checked her D-Dimer and labs and the result was normal. The Physician prescribed Reglan and Meclizine. The medication had helped, but she felt completely off. Dizziness had been coming and going since. Everything she does, she felt like she was walking turning directions. On that first day, it was terrible. After that day, it was coming and going. It was very mild on the next day, and she went back to work. It was reported that the dizziness was progressively getting worse. Whenever she sits in the office chairs, she had to move like a log. On 23May2021, the patient experienced joint pain. It was reported that mostly the left knee and elbows hurted really bad and she could not extend them. The patient had more pain in her elbows, but the knee pain is still there. On a pain scale from one to ten, her knees would be a three out of a ten and her elbows are still a six out of a ten. She was avoiding taking anything. She was not lifting any weight with her arms. Outcome of event pain was reported as, The patients pain level was a five or six, out of ten. She needs to take something for her pain level. If she tried to hold something, then her elbows remind that the pain still. She was having a easier time with her hands. Her elbows were bothering. Her knees were really bad, like an eight out of a ten. she had to wait some time to stand up and get going for the day and she would rate her knees a four out of a ten. It was reported that was not admitted in the hospital but she was under observation in the emergency department for three to four hours. She went for a follow up appointment after her hospital visit. Her primary care physician continued Meclizine to see if that would help her symptoms. She was waiting, she was going to return for another follow up. On 25Feb2021, the outcome of the fever was resolved. The outcome of the events nausea, headache was not recovered. The outcome of the chills, joint pain was unknown.   The reporter considered the events joint pain, dizziness and nausea were serious.; Sender's Comments: Based on the information available and a close temporal association, a possible contributory role of the suspect BNT162B2 cannot be excluded for the reported events of joint pain,dizziness,nausea,fever,chills .The case will be reassessed once new information is available. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate