Adrenal gland tumor; Brain fog; Depression; Anxiety; Cough; my depression and my anxiety has been worse; very sick; chest pain when taking breaths; runny nose; nose congestion; Fatigue; Headache; Nausea; Fever; all over body aches; This spontaneous case was reported by a consumer and describes the occurrence of ADRENAL NEOPLASM (Adrenal gland tumor), FEELING ABNORMAL (Brain fog), DEPRESSION (Depression), ANXIETY (Anxiety) and COUGH (Cough) in a 56-year-old patient of an unknown gender who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 032B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical information history was provided by the reporter.  Concomitant products included DULOXETINE HYDROCHLORIDE (CYMBALTA), GABAPENTIN and XYLOMETAZOLINE HYDROCHLORIDE (SUDAFED [XYLOMETAZOLINE HYDROCHLORIDE]) for an unknown indication.   On 27-May-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced ADRENAL NEOPLASM (Adrenal gland tumor), FEELING ABNORMAL (Brain fog), DEPRESSION (Depression), ANXIETY (Anxiety), COUGH (Cough), CONDITION AGGRAVATED (my depression and my anxiety has been worse), ILLNESS (very sick), CHEST PAIN (chest pain when taking breaths), RHINORRHOEA (runny nose), NASAL CONGESTION (nose congestion), FATIGUE (Fatigue), HEADACHE (Headache), NAUSEA (Nausea), PYREXIA (Fever) and MYALGIA (all over body aches). At the time of the report, ADRENAL NEOPLASM (Adrenal gland tumor), FEELING ABNORMAL (Brain fog), DEPRESSION (Depression), ANXIETY (Anxiety), COUGH (Cough), FATIGUE (Fatigue), HEADACHE (Headache), NAUSEA (Nausea) and PYREXIA (Fever) had not resolved and CONDITION AGGRAVATED (my depression and my anxiety has been worse), ILLNESS (very sick), CHEST PAIN (chest pain when taking breaths), RHINORRHOEA (runny nose), NASAL CONGESTION (nose congestion) and MYALGIA (all over body aches) outcome was unknown.            The reporter stated that after the second dose of moderna they have been very sick. The reported stated they have extreme fatigue, fever off and on, all over body aches, chest pain when taking breaths, headaches, runny nose, congestion and also reported that depression and anxiety have been worse.  The reporter stated they went to the ER and a small adrenal gland tumor was found. The reporter stated they have never had this before. The reporter stated that  lactatic acid levels are "PII(28):AQod6cLEamejIlM3WcvOork3DO1T".   Treatment  information was not provided by the reporter.  Nausea, fatigue, headache and pyrexia are consistent with the known safety profile of the product. However, in general very limited information has been provided regarding there events at this time.  More information about medical history and seriousness of the events was requested. Event adrenal glad tumor is considered not to be related with vaccine administration, but with previously undiagnosed condition. Patient previous medical history and diagnosed adrenal glad tumor may provide alterative justification for the events occurrence.   Most recent FOLLOW-UP information incorporated above includes: On 20-Jun-2021: Follow up received on 21-JUN-2021 - New events updated .; Sender's Comments: Nausea, Fatiga, Headache and pyrexia are consistent with the Known safety profile of the product. However, in general very limited information has been provided regarding there events at this time.  More information about medical history and seriousness of the events was requested. Event adrenal glad tumor is considered not to be related with vaccine administration, but with previously undiagnosed condition. Patient previous medical history and diagnosed adrenal glad tumor may provide alterative justification for the events occurrence.