no appetetite; losing a ton of weight; next day I got sick/soon it will be 3 months that I've been so sick and weak I'm living life on the couch/Since then I have been fully life disabled with a virus; weakness/I got the booster on 11/10 and literally dropped like a sack of potatoes the very next day; swollen lymph nodes; fatigue; fever; This spontaneous case was reported by a consumer and describes the occurrence of ILLNESS (next day I got sick/soon it will be 3 months that I've been so sick and weak I'm living life on the couch/Since then I have been fully life disabled with a virus) in an adult patient of an unknown gender who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. ASKU) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 10-Nov-2022, the patient received dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. On 10-Nov-2022, the patient experienced LYMPHADENOPATHY (swollen lymph nodes), FATIGUE (fatigue) and PYREXIA (fever). On 11-Nov-2022, the patient experienced ILLNESS (next day I got sick/soon it will be 3 months that I've been so sick and weak I'm living life on the couch/Since then I have been fully life disabled with a virus) (seriousness criterion disability) and ASTHENIA (weakness/I got the booster on 11/10 and literally dropped like a sack of potatoes the very next day). On an unknown date, the patient experienced DECREASED APPETITE (no appetetite) and WEIGHT DECREASED (losing a ton of weight). At the time of the report, ILLNESS (next day I got sick/soon it will be 3 months that I've been so sick and weak I'm living life on the couch/Since then I have been fully life disabled with a virus), ASTHENIA (weakness/I got the booster on 11/10 and literally dropped like a sack of potatoes the very next day), DECREASED APPETITE (no appetetite), WEIGHT DECREASED (losing a ton of weight), LYMPHADENOPATHY (swollen lymph nodes), FATIGUE (fatigue) and PYREXIA (fever) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: Negative. On an unknown date, Chest X-ray: Negative and Negative. On an unknown date, Computerised tomogram: Negative and Negative. On an unknown date, Viral test: Negative.     For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Unknown), the reporter considered ILLNESS (next day I got sick/soon it will be 3 months that I've been so sick and weak I'm living life on the couch/Since then I have been fully life disabled with a virus), ASTHENIA (weakness/I got the booster on 11/10 and literally dropped like a sack of potatoes the very next day), DECREASED APPETITE (no appetetite), WEIGHT DECREASED (losing a ton of weight), LYMPHADENOPATHY (swollen lymph nodes), FATIGUE (fatigue) and PYREXIA (fever) to be related.    Concomitant medication was not reported. Patient stated that, after receiving new omicron Moderna booster on 10-Nov-2022, since then patient had been fully life disabled with a virus  weakness, fatigue, fever, swollen lymph nodes, no appetite, losing a ton of weight and more. Patient had testing with infectious disease department for most of virus. Blood work, 2 CT scan and 2 chest X-rays came back as negative. Since booster, patient literally dropped like a sack of potatoes the very next day. Patient had been withering on the vine ever since. Every MD patient had seen including two visits to Hospital have said they could not find a virus but also think it was too much of a coincidence that one day patient got the shot and the next day patient got sick and soon it will be 3 months that patient had been so sick and weak. Patient living life on the couch and watching the world go by. Patient's PCP was very concerned about overall health. The only thing every MD had thought condition was connected to the vaccine. Treatment medication was not reported.  Company comment: This spontaneous case concerns an adult patient of unknown gender, with no medical history information reported, who experienced the unexpected serious (disability) event of illness and non serious events of  asthenia, decreased appetite, weight decreased, fatigue, lymphadenopathy and pyrexia. The events of asthenia and illness occurred approximately 1 day after a dose of mRNA-1273 bivalent BA.4/BA.5 (described as booster dose). No information about dose number or vaccination schedule was provided. As reported, after receiving new omicron Moderna booster patient had been fully life disabled with a virus  weakness, fatigue, fever, swollen lymph nodes, no appetite, losing a ton of weight and more. Patient had testing with infectious disease department for every virus and blood work came negative. Patient had 2 CT scan and 2 chest X-rays came back as negative. Reportedly, every MD patient had seen including two visits to Hospital have said they could not find a virus but also think it was too much of a coincidence that one day patient got the shot and the next day patient got sick and it will be 3 months that patient had been so sick and weak. The only thing every MD had thought condition was connected to the vaccine, as reported. Treatment medication was not reported. The events were not resolved. The benefit-risk relationship of mRNA-1273 bivalent BA.4/BA.5 is not affected by this report.