aggravated neuropathy; pain in shoulders, described as going up neck; cannot walk far before getting leg pain and starting to limp; ankles changing color and now turning blue; legs going numb, starting at ankles and now at mid-thighs which are tingling and itching; legs going numb, starting at ankles and now at mid-thighs which are tingling and itching; legs going numb, starting at ankles and now at mid-thighs which are tingling and itching; feeling very bad leg pains in both legs,constant right calf pain,pain in hand,pain in his wrists, elbows, and shoulders, described as going up on his neck,The pains are in his extremities and not his body cavity, feeling pulse while getting pain; pain in wrists, ankles, elbows/pain in shoulders, described as going up neck; pain at the injection site; vein pop out bulging all over legs when standing and walking; sleepless nights with severe pain; vascular symptoms, described as blood pressure spikes in the 150's/110 range; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of NEUROPATHY PERIPHERAL (aggravated neuropathy) in a 59-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 042L20A and 040A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Cancer (NOS) and Surgery (Patient had kidney surgery, back surgery, arm surgery, and a missing gall bladder.). Concomitant products included AMLODIPINE, LOSARTAN, UMECLIDINIUM BROMIDE, VILANTEROL TRIFENATATE (ANORO), GABAPENTIN, MULTIVITAMINS [VITAMINS NOS] and ASCORBIC ACID (VITAMIN C ACID) for an unknown indication.   On 10-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 10-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 14-Feb-2021, the patient experienced VARICOSE VEIN (vein pop out bulging all over legs when standing and walking), INSOMNIA (sleepless nights with severe pain), BLOOD PRESSURE INCREASED (vascular symptoms, described as blood pressure spikes in the 150's/110 range) and VACCINATION SITE PAIN (pain at the injection site). On an unknown date, the patient experienced NEUROPATHY PERIPHERAL (aggravated neuropathy) (seriousness criterion medically significant), NECK PAIN (pain in shoulders, described as going up neck), GAIT DISTURBANCE (cannot walk far before getting leg pain and starting to limp), SKIN DISCOLOURATION (ankles changing color and now turning blue), HYPOAESTHESIA (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), PARAESTHESIA (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), PRURITUS (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), PAIN IN EXTREMITY (feeling very bad leg pains in both legs,constant right calf pain,pain in hand,pain in his wrists, elbows, and shoulders, described as going up on his neck,The pains are in his extremities and not his body cavity, feeling pulse while getting pain) and ARTHRALGIA (pain in wrists, ankles, elbows/pain in shoulders, described as going up neck). At the time of the report, NEUROPATHY PERIPHERAL (aggravated neuropathy), NECK PAIN (pain in shoulders, described as going up neck), GAIT DISTURBANCE (cannot walk far before getting leg pain and starting to limp), SKIN DISCOLOURATION (ankles changing color and now turning blue), HYPOAESTHESIA (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), PARAESTHESIA (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), PRURITUS (legs going numb, starting at ankles and now at mid-thighs which are tingling and itching), VARICOSE VEIN (vein pop out bulging all over legs when standing and walking), INSOMNIA (sleepless nights with severe pain), BLOOD PRESSURE INCREASED (vascular symptoms, described as blood pressure spikes in the 150's/110 range), PAIN IN EXTREMITY (feeling very bad leg pains in both legs,constant right calf pain,pain in hand,pain in his wrists, elbows, and shoulders, described as going up on his neck,The pains are in his extremities and not his body cavity, feeling pulse while getting pain), ARTHRALGIA (pain in wrists, ankles, elbows/pain in shoulders, described as going up neck) and VACCINATION SITE PAIN (pain at the injection site) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2020, Nerve conduction studies: inconclusive (Inconclusive) Inconclusive. On 14-Feb-2021, Blood pressure measurement: increased having blood pressures in the 150's over 110 range.         Treatment of events was done with gabapentin. Concomitant drug includes Super Beets for heart health and blood pressure; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.