his hands and feet were freezing almost like Raynaud's; temperature of 101 degrees Fahrenheit; This is a spontaneous report from a contactable other hcp. A 66-years-old male patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/lot number: EL3302; Expiration Date: May2021) via an unspecified route of administration in Arm Left on 04Mar2021 15:00 (age at vaccination 66years old) as single dose for covid-19 immunisation. The patient medical history and concomitant medications. The patient had historical vaccine of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Batch/lot number: EL9266; Expiration Date: May2021) via an unspecified route of administration in unspecified date (age at vaccination 66years old) as single dose for covid-19 immunisation. The patient experienced that on 05Mar2021 13:00 patient had temperature of 101 degrees Fahrenheit, and his hands and feet were freezing almost like Raynaud's on an unspecified date. Clinical course was reported as her husband got his second dose of the Pfizer COVID-19 vaccine yesterday, and she would like to know if he can take Tylenol for his temperature of 101 degrees Fahrenheit. She says that the information provided about what and when things can be taken is confusing, they were told he could take Tylenol 24 hours later after the vaccine but not before that by her cardiologist when she called them and asked. She says that her husband got the injection yesterday at 03:00PM and at noon to 01:00PM today his temperature was 101 degrees Fahrenheit. Caller says last night her husband looked like he did, but he didn't. She says that the fact sheet they provide with the vaccination should have information about what medications to take. She says she didn't want to report her husband had anaphylactic or hives or anything on the website, so she called and whoever transferred her to this department said that she would get that information here. Caller clarifies that her husband did not have anaphylaxis or hives, she just wants to ask a simple question about whether or not he can take Tylenol since they were told it could negate quality of the vaccine if it is taken before and were told he could take it after by her cardiologist. Caller says some-thing about mammogram recommendations and something showing up on them if taken soon after vaccination, she does not clarify this statement. Caller says it's not like her husband had welts or anything, he has a fever of 101 degrees Fahrenheit, she got Modern vaccine and she didn't take anything for her temp of 100. Caller clarifies that her husband got his second dose of the Pfizer COVID-19 vaccine yesterday 04Mar and it was LOT EL3302 with EXP May2021. She says whoever wrote the information has handwriting that is not good, the NDC was not provided for either dose. She says her husband's first dose was LOT EL9266, to which he had no reactions, and EXP was May2021. She says both of her husband's doses were given at Hospital. Caller says that her vaccine doses were Modern, and her vaccine card has a lot of numbers on it. She says his second dose was given in his left arm. Caller says her husband has done no treatment yet for the fever, and his hands and feet were freezing almost like Raynaud's and his left hand was worse than his right, so she applied a heating pad to it to improve circulation, it was very weird. The patient underwent lab tests and procedures which included body temperature: 101 Fahrenheit on 05Mar2021. The clinical outcome of the events was unknown. Therapeutic measures were taken as a result of his hands and feet were freezing almost like Raynaud's.  No follow-up attempts are possible. No further information is expected.