Stiffness; Nausea; Lethargy; Headache; Rapid heartbeat; Labored breathing; Joint pain; All over leg pain; Pain at the injection site; Neck & chest tightness; chest tightness; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 52 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm right, administration date 16Feb2022 18:45 (Lot number: FJ6369) at the age of 52 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Thyroid Disease" (unspecified if ongoing), notes: Thyroid Disease; "Known allergies: Sulfur based meds only" (unspecified if ongoing), notes: Sulfur based meds only. Concomitant medication(s) included: SYNTHROID; ALLEGRA D; HYDROCHLOROTHIAZIDE. Vaccination history included: Bnt162b2 (Prev dose Product: COVID 19, Prev dose Brand: Pfizer/Biontech, Prev dose Lot number: FC3184, Prev dose Vaccine location: Right arm, Prev dose Dose number: 2), administration date: 25Aug2021, when the patient was 51 years old, for COVID-19 Immunization; Bnt162b2 (Prev dose Product: COVID 19, Prev dose Brand: Pfizer/Biontech, Prev dose Lot number: EW0177, Prev dose Vaccine location: Right arm, Prev dose Dose number: 1), administration date: 04Aug2021, when the patient was 51 years old, for COVID-19 Immunization. The following information was reported: MUSCULOSKELETAL STIFFNESS (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Stiffness"; NAUSEA (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Nausea"; LETHARGY (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Lethargy"; HEADACHE (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Headache"; HEART RATE INCREASED (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Rapid heartbeat"; DYSPNOEA (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Labored breathing"; ARTHRALGIA (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Joint pain"; PAIN IN EXTREMITY (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "All over leg pain"; VACCINATION SITE PAIN (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Pain at the injection site"; MUSCLE TIGHTNESS (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "Neck & chest tightness"; CHEST DISCOMFORT (non-serious) with onset 16Feb2022 07:30, outcome "not recovered", described as "chest tightness". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of musculoskeletal stiffness, nausea, lethargy, headache, heart rate increased, dyspnoea, arthralgia, pain in extremity, vaccination site pain, muscle tightness, chest discomfort.  Additional Information: Patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Patient was not diagnosed with COVID-19, prior to vaccination. Patient has not been tested for COVID-19 since the vaccination. No prolonged hospitalization.  Follow-up attempts are completed. No further information is expected.