KIDNEYS WERE NOT FUNCTIONING ANYMORE; A BLOOD CLOT IN LEFT LEG; LOST BOWEL MOVEMENT; PROSTATE WAS ENLARGED AND SWELLED UP; FELT LIKE SOMETHING AS HIT WITH A WALL OF BRICK; This spontaneous report received from a patient concerned a male of unspecified age, race and ethnicity. The patient's height and weight were not reported. No past medical history or concurrent conditions were reported. The patient previously received covid-19 vaccine ad26.cov2.s (dose number in series 1) (suspension for injection, route of admin and batch number were not reported, expiry: unknown) dose, start therapy date were not reported, 1 total administered for prophylactic vaccination. It was unknown whether patient had any adverse events following vaccination covid-19 vaccine ad26.cov2.s (dose number in series 1).   The patient received covid-19 vaccine ad26.cov2.s (dose number in series 2) (booster dose) (suspension for injection, route of admin and batch number were not reported, expiry; unknown) dose was not reported, 1 total administered on DEC-2021 for prophylactic vaccination. The batch number was not reported and has been requested. No concomitant medications were reported. The patient said that the second day following the vaccination, he felt like something "hit him with a wall of brick". It was mentioned that the patient lost his bowel movement and was not going well, so his wife had to call the fire department for help, but the patient refused to go to the emergency room (ER) that day. It was reported that, 1 to 2 days passed the patient was not able to go to the bathroom so he finally decided to go to the emergency room (ER) and the patient was inserted a Fowley catheter to drain the urine. After draining 9 L (litters) in 24 hours, performed multiples tests which were indicating that his kidneys were not functioning anymore. The doctor also discovered a blood clot in his left leg. It was mentioned that 6 days later, he was able to return home with some medication that helped his kidneys to recover from all of this. It was mention that the patient had to do physical therapy, and he had a visiting nurse for 4 to 6 weeks. He had to take appointment with a neurologist and he wanted to take the Fowley out, but the doctor found out that his prostate was enlarge and swelled up which was explaining why he could not urinate on his own. For that reason, he had to keep the Fowley catheter and it was mentioned that the next month from the day of reporting the patient will have an operation which will allow the doctor to remove the catheter. On an unspecified date the patient was hospitalized and discharged from the hospital in 6 days (dose number in series 2). The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The outcome of the kidneys were not functioning anymore, prostate was enlarged and swelled up, a blood clot in left leg, felt like something as hit with a wall of brick and lost bowel movement was not reported. This report was serious (Hospitalization Caused / Prolonged).; Sender's Comments: V0: 20220644078-covid-19 vaccine ad26.cov2.s- kidneys were not functioning anymore, a blood clot in left leg, prostate was enlarged and swelled up and lost bowel movement. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s). Therefore, this event(s) is considered unassessable.