pulmonary embolism; two blood clots in her lungs; she was depressed about that,; migraine; cough; pretty weak; shortness of breath; has a low appetite; This is a spontaneous report from a contactable consumer (patient herself) via a Pfizer-sponsored program, Support. A 52-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection; Batch/Lot Number: EN6208) via an unspecified route of administration on 02Apr2021 (at the age of 52 years old) as dose 2, single for COVID-19 immunisation. Medical history included blood clot and deep vein thrombosis (DVT) back in 2012 that broke off and it did go to her lungs. Patient had a pulmonary embolism and pneumonia with the last blood clot 9 years ago, and high blood pressure which puts the patient more at risk. The patient also experienced a COVID in Oct2020 wherein she had brain fog and loss of taste and sense of smell. Patient stated that she was curious as to how this happens again. The patient's concomitant medications were not reported. Historical vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; lot: EN6198) on 10Mar2021 (at the age of 52 years old) as dose 1 for COVID-19 immunisation. On unspecified date in 2021, it was reported that the patient experienced two blood clots in her lungs and pulmonary embolism (hospitalization). The patient just got released from the hospital yesterday evening and they found that she has blood clots; she had gotten the blood clots in the lungs and experienced other side effects, shortness of breath, so she will have to take blood thinners to the rest of her life and she was depressed about that, so she wanted to know if that could be related to the COVID-19 vaccine. She stated that this was a second blood clot, and that she had a blood clot back in 2012, and even though it was a 9 years ago she was wondering if this time it could be related to the vaccine. Patient was totally shocked as this was her second one, she clarified her second blood clot. The patient thought maybe the first time was because she was on birth control pills and that may have accelerated it and the first time she had them, she had a warning, stated her leg like her calf was hurting but this time there was no leg pain, and it was automatically in her lungs; she had a cough and shortness of breath. Patient stated that she did not want to get Covid, stated that she already had Covid last October, stated that she did not want to get it again that it was terrible. Initially she thought she had Covid again last Oct2021 (as reported; pending clarification), and has had some long-hauler symptoms and this was prior to the vaccines. The patient also stated that she thought she got Covid again because of the shortness of breath and cough, and cannot imagine how she would have gotten Covid again, she had been wearing a mask everywhere since the other variants have picked up. The patient clarified that she went to the ER Sunday night, 26Sep2021, stated it was because she got scared, she had called the telehealth doc and they immediately said she had a blood clot.  The patient had symptoms for a while, unknown exact date symptoms started, went to ER, and they did a CT scan, which showed blood clots on each side of lungs seen. The patient was admitted for one night, discharged yesterday 27Sep2021, and it was reported that the symptoms last week was a bad week and she started with a migraine on Wednesday last week, short of breath and then Thursday evening the cough came along with the shortness of breath. Patient thought maybe this really started before this, maybe in Jul or Aug2021, two different nurse practitioners mentioned her shortness of breath at that time. They thought it may be allergies or something, states they kept blowing her off. Patient stated she asked to see a specialist to check heart and lungs after recovering from Covid and see about those long-haul symptoms. The first time she had blood clots, she was in the hospital for 5-6 days, states this time she was only there for one night, she was treated with blood thinner, first started her with an IV drip bag, unknown name of medication, then gave her one dose of Eliquis and has to pick up prescription for Eliquis, has missed a dose of the Eliquis because it was not ready at the pharmacy. Stated it was serious, she has come close to death twice, should be ready to pick up around 6 PM and she really needs that medication. No further details provided. States her symptoms are not as bad as they were, and she still was pretty weak and has a low appetite, she was eating but just not very hungry. The outcome of the event pulmonary embolism and thrombosis pulmonary was recovering, while for the other events was unknown.  Follow-up attempts are completed. No further information is expected.