This spontaneous case was reported by a patient and describes the occurrence of AUTOIMMUNE DISORDER (Patient thinks she has an autoimmune condition but doesn't know which one since there are many, doctors haven't been able to help her), MOBILITY DECREASED (Patient couldn't get out of bed, felt like a snake), PAIN (Was in such pain/patient thinks it'll go away and it does a little but then comes back/if she lifted her arms a certain way she'd be in pain/every single part of her body sore and was in pain), PAIN (every single part of her body sore and was in pain) and ASTHENIA (Patient didn't have strength/patient used to be pretty strong) in an 83-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 037A21B and 011A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 03-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 01-Apr-2021, the patient experienced AUTOIMMUNE DISORDER (Patient thinks she has an autoimmune condition but doesn't know which one since there are many, doctors haven't been able to help her), MOBILITY DECREASED (Patient couldn't get out of bed, felt like a snake), PAIN (Was in such pain/patient thinks it'll go away and it does a little but then comes back./if she lifted her arms a certain way she'd be in pain/every single part of her body sore and was in pain), PAIN (every single part of her body sore and was in pain), ASTHENIA (Patient didn't have strength/patient used to be pretty strong), HYPOTONIA (Patient is mushy she has lost muscle tone, patient used to be pretty strong), FEELING ABNORMAL (This is terrible and ridiculous), DEPRESSED MOOD (Patient is depressed and annoyed because she can't do things like before), IRRITABILITY (Patient is depressed and annoyed because she can't do things like before), FATIGUE (patient was in pain and tired/Patient feels very fatigue and tired) and MYALGIA (every single part of her body sore). The patient was treated with PREDNISONE at an unspecified dose and frequency and PREDNISOLONE at an unspecified dose and frequency. At the time of the report, AUTOIMMUNE DISORDER (Patient thinks she has an autoimmune condition but doesn't know which one since there are many, doctors haven't been able to help her), MOBILITY DECREASED (Patient couldn't get out of bed, felt like a snake), PAIN (Was in such pain/patient thinks it'll go away and it does a little but then comes back./if she lifted her arms a certain way she'd be in pain/every single part of her body sore and was in pain), PAIN (every single part of her body sore and was in pain), ASTHENIA (Patient didn't have strength/patient used to be pretty strong), HYPOTONIA (Patient is mushy she has lost muscle tone, patient used to be pretty strong), FEELING ABNORMAL (This is terrible and ridiculous), DEPRESSED MOOD (Patient is depressed and annoyed because she can't do things like before), IRRITABILITY (Patient is depressed and annoyed because she can't do things like before), FATIGUE (patient was in pain and tired/Patient feels very fatigue and tired) and MYALGIA (every single part of her body sore) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Eosinophil count: had little eosinophils (Low) Had little eosinophils. On an unknown date, Lymphocyte count: had little lymphocytes had little lymphocytes (Low) Had little lymphocytes. Concomitant product use was not provided by the reporter. Patient stated that she was very well before the shot. Patient stated she hasn't been to the doctor in 16 years before taking the vaccines. Patient has been to many doctors, physical therapy, rheumatologists, has done acupuncture. Treatment included acupuncture. This case was linked to MOD-2022-587442 (Patient Link).