showed a blockage; classic angina; suffered a cardiac arrest; collapsed; scream for help; Felt quite tired; This spontaneous case was reported by a consumer and describes the occurrence of ATRIOVENTRICULAR BLOCK (showed a blockage), ANGINA PECTORIS (classic angina), CARDIAC ARREST (suffered a cardiac arrest) and CIRCULATORY COLLAPSE (collapsed) in a 39-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 044B21A and 029A212) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Felt ill (In February or march this year patient felt ill) in 2021, Stress (In February or march this year she felt ill, and diagnosed with stress related symptoms) in 2021, Anxiety (In February or march this year she felt ill, and diagnosed with anxiety related symptoms) in 2021, Acid reflux (esophageal) in 2021 and Sickness (Around thanksgiving last year patient got sick.) in 2020. Family history included Cardiac disorder (Patient has a family history of cardiac issues with her dad and uncle.).   On 06-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 14-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 14-Apr-2021, the patient experienced FATIGUE (Felt quite tired). On 10-Oct-2021, the patient experienced ATRIOVENTRICULAR BLOCK (showed a blockage) (seriousness criterion hospitalization), ANGINA PECTORIS (classic angina) (seriousness criterion medically significant), CARDIAC ARREST (suffered a cardiac arrest) (seriousness criterion medically significant), CIRCULATORY COLLAPSE (collapsed) (seriousness criterion medically significant) and SCREAMING (scream for help). The patient was hospitalized on 10-Oct-2021 due to ATRIOVENTRICULAR BLOCK. At the time of the report, ATRIOVENTRICULAR BLOCK (showed a blockage), ANGINA PECTORIS (classic angina), CARDIAC ARREST (suffered a cardiac arrest), CIRCULATORY COLLAPSE (collapsed), SCREAMING (scream for help) and FATIGUE (Felt quite tired) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 10-Oct-2021, Imaging procedure: abnormal (abnormal) Imaging with dye showed a blockage.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant medication was not provided by the reporter. Treatment medications was not provided by the reporter. Patient admitted to the hospital and was done imaging with dye which showed a blockage and had a stent placed. On 10-Oct-2021 patient cardiac arrest. Patient  had collapsed, but was able to scream for help. A cardiac surgeon stopped running to help her, performed CPR, mouth to mouth, and used a defibrillator to try and resuscitate her. The surgeon stated her symptoms were a classic angina. Patient  was taken to the emergency room where she was then life flighted to a hospital in Boston. They did not do any tests at the emergency room, but at the admitting hospital she was given imaging with dye which showed a blockage. They placed a stent for her. They suspect that the cause of her symptoms were due to some kind of genetic defect. Patient had a family history of cardiac issues with her dad an uncle.  Company Comment: This case concerns a 39-year-old, female patient with no relevant medical history reported, who experienced the unexpected events of atrioventricular block, angina pectoris, cardiac arrest and circulatory collapse. The events occurred 5 months and 27 days after the second dose of mRNA-1273 Moderna vaccine. The rechallenge was not applicable since the events happened after the second dose. The benefit-risk relationship of mRNA-1273 Moderna vaccine in not affected by this report.   This case was linked to MOD-2021-370157 (Patient Link).; Sender's Comments: This case concerns a 39-year-old, female patient with no relevant medical history reported, who experienced the unexpected events of atrioventricular block, angina pectoris, cardiac arrest and circulatory collapse. The events occurred 5 months and 27 days after the second dose of mRNA-1273 Moderna vaccine. The rechallenge was not applicable since the events happened after the second dose. The benefit-risk relationship of mRNA-1273 Moderna vaccine in not affected by this report.