his autoimmune system is attacking him, he is being attacked by the Pfizer medication; He is Dying; flushing; trouble paying attention; He now has dramatic weight loss; He's gained about 15 pounds.; lose energy; makes him feel terrible; restless leg feeling; muscles hurt; feel terrible/feels like a hole in the gut; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  An 82-year-old male patient received BNT162b2 (BNT162B2), on 12Oct2021 as dose 3 (booster), single (Lot number: FE3592) at the age of 81 years for covid-19 immunisation. The patient's relevant medical history included: "PTSD" (unspecified if ongoing); "severe anxiety" (unspecified if ongoing); "Depression" (unspecified if ongoing); "he starts his day with a thyroid pill" (unspecified if ongoing). Concomitant medication(s) included: SYNTHROID; AMLODIPINE; PAROXETINE; PANTOPRAZOLE; LOPERAMIDE; ATORVASTATIN CALCIUM; TAMSULOSIN; FINASTERIDE; FAMOTIDINE; ESZOPICLONE taken for sleep disorder; MELATONIN; PROBIOTICS. Vaccination history included: BNT162b2 (First dose: Date 27Jan2021, he initially states the Lot is Unknown but then later in the call provides EL1283), administration date: 27Jan2021, when the patient was 80-year-old, for COVID-19 immunization; BNT162b2 (Second Dose: Date 17Feb2021 Lot EL8982.), administration date: 17Feb2021, when the patient was 80-year-old, for COVID-19 immunization, reaction(s): "his autoimmune system is attacking him, he is being attacked by the Pfizer medication", "He is Dying", "Flushing", "impacting all bodily functions", "trouble paying attention", "He now has dramatic weight loss", "He's gained about 15 pounds.", "lose energy", "makes him feel terrible", "restless leg feeling", "muscles hurt". The following information was reported: AUTOIMMUNE DISORDER (medically significant, life threatening), outcome "unknown", described as "his autoimmune system is attacking him, he is being attacked by the Pfizer medication"; ILL-DEFINED DISORDER (life threatening), outcome "unknown", described as "He is Dying"; FLUSHING (non-serious), outcome "not recovered"; DISTURBANCE IN ATTENTION (non-serious), outcome "unknown", described as "trouble paying attention"; WEIGHT DECREASED (non-serious), outcome "unknown", described as "He now has dramatic weight loss"; WEIGHT INCREASED (non-serious), outcome "unknown", described as "He's gained about 15 pounds."; ASTHENIA (non-serious), outcome "unknown", described as "lose energy"; MALAISE (non-serious), outcome "unknown", described as "makes him feel terrible"; RESTLESS LEGS SYNDROME (non-serious), outcome "unknown", described as "restless leg feeling"; MYALGIA (non-serious), outcome "unknown", described as "muscles hurt"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "feel terrible/feels like a hole in the gut". The events "his autoimmune system is attacking him, he is being attacked by the pfizer medication" and "he is dying" required emergency room visit. The patient underwent the following laboratory tests and procedures: Computerised tomogram: unknown results; Weight: 155 lbs, notes: 155 before,; 160 lbs, notes: he got a little heavier within the last month and a half; 170 lbs, notes: now he is 170, that is more accurate. He's gained about 15 pounds. Therapeutic measures were taken as a result of autoimmune disorder, ill-defined disorder, flushing, disturbance in attention, weight decreased, weight increased, asthenia, malaise, restless legs syndrome, myalgia. The patient reported that the Flushing began right after the second shot, Mar2021. He had dramatic weight loss, did a Cat Scan. He had Autoimmune disorders and takes 19 different medications. He refused to take the 4th dose, he thinks he figured his autoimmune system was being attacked, after he took the second dose, he reported to his primary care doctor on 30Mar2021 that he is flushing. The Flushing started by the end of the month in Feb2021, he does not know specific dates of when the flushing started, it flies over his head. Weight: He provides 160, then stated that he got a little heavier within the last month and a half, he was down to 155 before, but now he is 170, that is more accurate. He gained about 15 pounds. He had Dry Flushing, in which it makes him lose energy, makes him feel terrible, to the point that he has that restless leg feeling, feels like a hole in the gut, certain points in the day, every time he eats or drinks or anything he will flush. He starts his day with a thyroid pill at 7 in the morning and he has medications that continue till 11. He has to do with his eyes, drops, then wash eyelids with pad etc. Every part of his body is affected. He takes probiotics on schedule to be able to go bathroom, he has medication not leak pee wise. He was treated with Prednisone for the muscle pain, it was prescribed recently, he has been on prednisone for 3 or 4 months.