MUSCLE CRAMPS; SORE RIB CAGE; EATS SOMETHING IT TASTED LIKE DIARRHEA; CHILLS; WOKE UP SEVERAL TIMES WITH HANDS AND FINGERS THROBBING; NOT FEELING SO GOOD DURING THE DAY AND BY EVENING NOT FEELING GOOD AT ALL; FELT REALLY TIRED/EXTREMELY TIRED; NAUSEA; DIARRHEA WORSEN/WATERY DIARRHEA; ALL MUSCLES ACHING; This spontaneous report received from a patient concerned a 60 year old female. The patient's height, and weight were not reported. The patient's pre-existing medical conditions included: Patient had no known allergies. Patient was taking vitamin supplements only and had excellent health.  The patient previously received covid-19 vaccine ad26.cov2.s (Dose number in series 1) (suspension for injection, route of admin, and batch number were not reported, expiry: unknown) dose was not reported, 1 total, administered on an unspecified date in JAN-2022 to left arm for prophylactic vaccination. On an unspecified date, the patient felt different/felt like coming down with something/felt not 100 percent/did not felt best. Patient also stated it all lasted a couple days and has resolved since (Dose number in series 1). The patient received booster dose of covid-19 vaccine ad26.cov2.s (Dose number in series 2) (suspension for injection, route of admin, and batch number were not reported, expiry: unknown) dose was not reported, 1 total, administered on 26-MAR-2022 to left arm for prophylactic vaccination. The batch number was not reported and has been requested. No concomitant medications were reported.  On 26-MAR-2022, (Saturday) patient was not feeling so good during the day and by evening not feeling good at all, felt really tired, muscle cramps, woke up several times with hands and fingers throbbing, sore rib cage, all muscles aching, extremely tired, nausea, diarrhea. Patient also experienced chills on Saturday overnight and for the 2 days after. Patient also stated that patient was not able to eat because all smells was diarrhea and that when patient eats something it tasted like diarrhea since Saturday night. (Dose number in series 2). On 27-MAR-2022 (Sunday), patient reported was bad, felt so tired and exhausted and fatigued, had muscle aches, diarrhea, nausea, could not even sit up (Dose number in series 2). On 28-MAR-2022 (Monday), patient felt better but it returned just not as bad as Sunday, not feeling good, diarrhea, tiredness, muscle aches, nausea. Patient stated these side effects have continued since and were maybe a bit better but the diarrhea was worse and was now watery (Dose number in series 2). On 31-MAR-2022, patient still had muscle aches that were almost totally gone, tiredness was still there but was 25 percent remaining only, hand/fingers throbbing was not back to normal but almost totally gone with 10 percent remaining, sore rib cage was resolved mostly with 10 percent remaining. Patient stated that biggest issue was diarrhea. The nausea came and went but patient was not retching or bringing up vomit. Patient stated that she had 10 episodes of diarrhea in the past 24 hours (Dose number in series 2).  The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from chills on 29-MAR-2022, was recovering from felt really tired/extremely tired, nausea, woke up several times with hands and fingers throbbing, sore rib cage, all muscles aching, and not feeling so good during the day and by evening not feeling good at all, had not recovered from diarrhea worsen/watery diarrhea and the outcome of muscle cramps and eats something it tasted like diarrhea was not reported. This report was non-serious. This case, involving the same patient is linked to 20220400853 (Dose number in series 1).; Sender's Comments: V0- Medical assessment comment is not required as per standard procedure as case was assessed as non-serious