This spontaneous case was reported by a consumer and describes the occurrence of BEDRIDDEN, MIGRAINE, NECK PAIN, VACCINATION SITE MASS, and BREAST SWELLING in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 064H21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Undifferentiated connective tissue disease. Concurrent medical conditions included Allergy to Penicillin and Lactose intolerance.    On 30-Nov-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Nov-2021, the patient experienced BEDRIDDEN, PAIN IN EXTREMITY, DIZZINESS, BREAST SWELLING, BREAST PAIN, PYREXIA, MYALGIA, RASH, LYMPH NODE PAIN, LYMPHADENOPATHY, FATIGUE, HEADACHE, and ARTHRALGIA. 30-Nov-2021, the patient experienced MIGRAINE, NECK PAIN, VACCINATION SITE MASS, BREAST SWELLING, ILLNESS, and VACCINATION SITE LYMPHADENOPATHY. On an unknown date, the patient experienced VACCINATION SITE MASS, VACCINATION SITE PRURITUS, and VACCINATION SITE ERYTHEMA. The patient was treated with PARACETAMOL for Adverse event, at a dose of every 4 hours X 2 days. At the time of the report, BEDRIDDEN, MIGRAINE, VACCINATION SITE MASS, BREAST SWELLING, ILLNESS, PAIN IN EXTREMITY, DIZZINESS, VACCINATION SITE MASS, BREAST SWELLING, BREAST PAIN, VACCINATION SITE PRURITUS, VACCINATION SITE ERYTHEMA, VACCINATION SITE LYMPHADENOPATHY, MYALGIA, RASH, LYMPH NODE PAIN, LYMPHADENOPATHY, FATIGUE, HEADACHE, and ARTHRALGIA had not resolved and NECK PAIN and PYREXIA had resolved.      No concomitant medications were reported. Patient reports having an adverse reaction after the second dose of the Moderna vaccine. Onset was about 24 hours after the shot. They were sick for 7 days, in bed for 4, with a 101°F fever, large muscle pain, and joint pain. After about 30 hours of the second shot they took Nyquil. Then, 2 weeks after the shot, their lymph nodes under the left arm swelled till the ribs and were consistently swelled for 2 weeks and then went on to been intermittently swelled for 5 months.   First dose was on 12Mar2021, lot 044A21A (left arm), second dose was on 09Apr2021, lot 032B21A (left arm), booster dose was 30Nov2021, lot 064H21A (right arm). Patient state they do not take any medication regularly.  Patient inquires what they can do to feel better and if there is any recommendation for future doses of the vaccine given their adverse events.  As a side note, pay attention to on line forums. What patient describing here is not abnormal and you should not ignore it. You need to pay attention and advise medical professionals accordingly.  It was reported that patient experienced Large muscle and joint pain X 7 days on day of this report. Headache and neck pain returned day 6. Day 2 through date of this report (day 7), lymph nodes under right are swollen, and painful, right breast swollen and painful. Significant fatigue to date (day 7).   This case was linked to MOD-2021-404048 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes on 06-Dec-2021 Follow up received, patient information, medical history, events added, and outcome update.