pain had spread into the back of my skull and very tender; extreme pain and swelling in left lymph node; Swelling in her lymph node on the same side where she got the shot/has gotten bigger/ knot growing out of my left lymph node; Sinus issues like colds; extreme pain in neck; unable to turn neck; sick at my stomach; double ear ache; lots of drainage in ears, nose and throat; no energy; out of breath; lots of drainage in ears; dizziness; sore in chest when breathing; severe cold symptoms; soft ball size knot grow at the injection site; extreme fatigue; body aches; Arm where she got the shot is very sore; feverish; This spontaneous case was reported by a consumer and describes the occurrence of LYMPH NODE PAIN (extreme pain and swelling in left lymph node), HEADACHE (pain had spread into the back of my skull and very tender) and LYMPHADENOPATHY (Swelling in her lymph node on the same side where she got the shot/has gotten bigger/ knot growing out of my left lymph node) in a 31-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 078C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Endometrial disorder NOS (Endometriosis) and Hysterotomy in July 2018. Concurrent medical conditions included Depression and Bipolar disorder. Concomitant products included LAMOTRIGINE from 10-Jul-2021 to an unknown date for Bipolar affective disorder, PAROXETINE HYDROCHLORIDE (PAXIL [PAROXETINE HYDROCHLORIDE]) from 15-Feb-2018 to an unknown date for Depression.    On 28-Jul-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Aug-2021, the patient experienced LYMPHADENOPATHY (Swelling in her lymph node on the same side where she got the shot/has gotten bigger/ knot growing out of my left lymph node) (seriousness criterion hospitalization). On 02-Aug-2021, the patient experienced LYMPH NODE PAIN (extreme pain and swelling in left lymph node) (seriousness criterion hospitalization). On 03-Aug-2021, the patient experienced HEADACHE (pain had spread into the back of my skull and very tender) (seriousness criterion hospitalization). On an unknown date, the patient experienced NASOPHARYNGITIS (Sinus issues like colds), NECK PAIN (extreme pain in neck), MOBILITY DECREASED (unable to turn neck), ABDOMINAL DISCOMFORT (sick at my stomach), EAR PAIN (double ear ache), RHINORRHOEA (lots of drainage in ears, nose and throat), ASTHENIA (no energy), DYSPNOEA (out of breath), OTORRHOEA (lots of drainage in ears), DIZZINESS (dizziness), CHEST PAIN (sore in chest when breathing), NASOPHARYNGITIS (severe cold symptoms), VACCINATION SITE INDURATION (soft ball size knot grow at the injection site), FATIGUE (extreme fatigue), MYALGIA (body aches), VACCINATION SITE PAIN (Arm where she got the shot is very sore) and PYREXIA (feverish). The patient was hospitalized on 02-Aug-2021 due to LYMPH NODE PAIN and LYMPHADENOPATHY. At the time of the report, LYMPH NODE PAIN (extreme pain and swelling in left lymph node), HEADACHE (pain had spread into the back of my skull and very tender), LYMPHADENOPATHY (Swelling in her lymph node on the same side where she got the shot/has gotten bigger/ knot growing out of my left lymph node) and VACCINATION SITE INDURATION (soft ball size knot grow at the injection site) had not resolved and NASOPHARYNGITIS (Sinus issues like colds), NECK PAIN (extreme pain in neck), MOBILITY DECREASED (unable to turn neck), ABDOMINAL DISCOMFORT (sick at my stomach), EAR PAIN (double ear ache), RHINORRHOEA (lots of drainage in ears, nose and throat), ASTHENIA (no energy), DYSPNOEA (out of breath), OTORRHOEA (lots of drainage in ears), DIZZINESS (dizziness), CHEST PAIN (sore in chest when breathing), NASOPHARYNGITIS (severe cold symptoms), FATIGUE (extreme fatigue), MYALGIA (body aches), VACCINATION SITE PAIN (Arm where she got the shot is very sore) and PYREXIA (feverish) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       Concomitant medication included anti-depressants and over the counter medication.  Treatment information was not provided.  The patient applied heating pad for her symptoms.  The patient reported that she the swelling on her left side has gotten bigger from the bottom of her neck and now up to her back.  Physician (friend) advised to use compresses and massage was noted.  Company comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   Most recent FOLLOW-UP information incorporated above includes: On 09-Aug-2021: Follow up received included additional Information received included patient demographics, historical conditions, concomitants, new events, case upgraded to serious and start date of event  were added and event oucomes were updated.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.