Arms jumping involuntarily out of her hospital bed; Tachycardia; Dizzy; Severe gastrointestinal issues; Head, neck, arms, hands and body began tingling; difficulty breathing; tingling arms jumping involuntarily/ fasciculations; low blood pressure; Dysautonomia; nausea; erytheme; pericardial effusion; chest pain; neuropathies; burning eyes; Pulsatile and tonal tinnitus; Inappetence; Severe pain in my neck; Severe pain in my back; Anxiety; Severe pain in Achilles tendons; pain in hip torso /joints; bone pain; Sinus pressure; Cardiac edema; Adrenaline dumps a blood clot; I felt horrible and I knewsomething wasn't right this was the first of five ER trips; This literature-non-study case was reported in a literature article and describes the occurrence of TACHYCARDIA (Tachycardia), DIZZINESS (Dizzy), GASTROINTESTINAL DISORDER (Severe gastrointestinal issues), PARAESTHESIA (Head, neck, arms, hands and body began tingling), DYSPNOEA (difficulty breathing), MUSCLE CONTRACTIONS INVOLUNTARY (tingling arms jumping involuntarily/ fasciculations), HYPOTENSION (low blood pressure), AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia), NAUSEA (nausea), ERYTHEMA (erytheme), PERICARDIAL EFFUSION (pericardial effusion), CHEST PAIN (chest pain), NEUROPATHY PERIPHERAL (neuropathies), EYE IRRITATION (burning eyes), TINNITUS (Pulsatile and tonal tinnitus), DECREASED APPETITE (Inappetence), NECK PAIN (Severe pain in my neck), BACK PAIN (Severe pain in my back), ANXIETY (Anxiety), TENDON PAIN (Severe pain in Achilles tendons), ARTHRALGIA (pain in hip torso /joints), BONE PAIN (bone pain), PARANASAL SINUS DISCOMFORT (Sinus pressure), OEDEMA DUE TO CARDIAC DISEASE (Cardiac edema), THROMBOSIS (Adrenaline dumps a blood clot), FEELING ABNORMAL (I felt horrible and I knewsomething wasn't right this was the first of five ER trips) and TREMOR (Arms jumping involuntarily out of her hospital bed) in a 50-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.      No Medical History information was reported.    In December 2021, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In December 2021, the patient experienced TACHYCARDIA (Tachycardia) (seriousness criterion hospitalization), DIZZINESS (Dizzy) (seriousness criterion hospitalization), GASTROINTESTINAL DISORDER (Severe gastrointestinal issues) (seriousness criterion hospitalization), PARAESTHESIA (Head, neck, arms, hands and body began tingling) (seriousness criterion hospitalization), DYSPNOEA (difficulty breathing) (seriousness criterion hospitalization), MUSCLE CONTRACTIONS INVOLUNTARY (tingling arms jumping involuntarily/ fasciculations) (seriousness criterion hospitalization), HYPOTENSION (low blood pressure) (seriousness criterion hospitalization), AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia) (seriousness criterion hospitalization), NAUSEA (nausea) (seriousness criterion hospitalization), ERYTHEMA (erytheme) (seriousness criterion hospitalization), PERICARDIAL EFFUSION (pericardial effusion) (seriousness criteria hospitalization and medically significant), CHEST PAIN (chest pain) (seriousness criterion hospitalization), NEUROPATHY PERIPHERAL (neuropathies) (seriousness criteria hospitalization and medically significant), EYE IRRITATION (burning eyes) (seriousness criterion hospitalization), TINNITUS (Pulsatile and tonal tinnitus) (seriousness criterion hospitalization), DECREASED APPETITE (Inappetence) (seriousness criterion hospitalization), NECK PAIN (Severe pain in my neck) (seriousness criterion hospitalization), BACK PAIN (Severe pain in my back) (seriousness criterion hospitalization), ANXIETY (Anxiety) (seriousness criterion hospitalization), TENDON PAIN (Severe pain in Achilles tendons) (seriousness criterion hospitalization), ARTHRALGIA (pain in hip torso /joints) (seriousness criterion hospitalization), BONE PAIN (bone pain) (seriousness criterion hospitalization), PARANASAL SINUS DISCOMFORT (Sinus pressure) (seriousness criterion hospitalization), OEDEMA DUE TO CARDIAC DISEASE (Cardiac edema) (seriousness criterion hospitalization), THROMBOSIS (Adrenaline dumps a blood clot) (seriousness criteria hospitalization and medically significant) and FEELING ABNORMAL (I felt horrible and I knewsomething wasn't right this was the first of five ER trips) (seriousness criterion hospitalization). On an unknown date, the patient experienced TREMOR (Arms jumping involuntarily out of her hospital bed) (seriousness criterion hospitalization). At the time of the report, TACHYCARDIA (Tachycardia), DIZZINESS (Dizzy), GASTROINTESTINAL DISORDER (Severe gastrointestinal issues), PARAESTHESIA (Head, neck, arms, hands and body began tingling), DYSPNOEA (difficulty breathing), MUSCLE CONTRACTIONS INVOLUNTARY (tingling arms jumping involuntarily/ fasciculations), HYPOTENSION (low blood pressure), AUTONOMIC NERVOUS SYSTEM IMBALANCE (Dysautonomia), NAUSEA (nausea), ERYTHEMA (erytheme), PERICARDIAL EFFUSION (pericardial effusion), CHEST PAIN (chest pain), NEUROPATHY PERIPHERAL (neuropathies), EYE IRRITATION (burning eyes), TINNITUS (Pulsatile and tonal tinnitus), DECREASED APPETITE (Inappetence), NECK PAIN (Severe pain in my neck), BACK PAIN (Severe pain in my back), ANXIETY (Anxiety), TENDON PAIN (Severe pain in Achilles tendons), ARTHRALGIA (pain in hip torso /joints), BONE PAIN (bone pain), PARANASAL SINUS DISCOMFORT (Sinus pressure), OEDEMA DUE TO CARDIAC DISEASE (Cardiac edema), THROMBOSIS (Adrenaline dumps a blood clot) and FEELING ABNORMAL (I felt horrible and I knewsomething wasn't right this was the first of five ER trips) was resolving and TREMOR (Arms jumping involuntarily out of her hospital bed) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: Low. On an unknown date, Echocardiogram: abnormal. On an unknown date, Electrocardiogram: abnormal.         No concomitant medications were reported.  It was reported that patient was admitted to the to the hospital after MVP testing after the next 24 hours.Patient was released with no definitive diagnosis except maybe considering the timeline, that the patient was having a reaction to the booster. Patient hands were champing closed.  Patient felt horrible and knew something wasn't right as this was the first of five ER (emergency room) trips.  Patient had 2 hospital stays and a cascade of doctor and specialist visits with symptoms multiplying by the day it was affirmed that patient was having a severe reaction to the Moderna booster. The patient soon had a team of specialists in cardiology, neurology, rheumatology, gastroenterology, hematology, immunology, infectious disease and POTS who were all treating patients suffering from COVID vaccine injury.   Each of these specialists surmise the COVID vaccine could trigger the autonomic nervous system which also in just about every other system in the body.  It was reported that for four months patient was too dizzy to drive and spent the lion's share of her days resting at home this meant not being able to take her daughter to school or attend her ski races  It was reported that patient was lifelong athlete, and at time of reporting she was on beta blockers, who was eventually able to ride a stationary bike alongside PBG alongside heart patients in their 80s, in therapeutic body work her naturopathic doctors and support of other people in the same boat had been God sends in supporting her recovery. (as reported).   Patient reported still wake not knowing what symptoms would be lurking. They continue to come in waves while many had waned several linger and affected her day-to-day living the patient was worried about what lasting damage had been done to her body.  Company comment: This is a literature non-study case concerning a 50 year-old, female patient with no reported medical history except for being a lifelong athlete, who experienced the serious (due to hospitalization) unexpected events of Tachycardia, Dizzy, Severe gastrointestinal issues, Head, neck, arms, hands and body began tingling, difficulty breathing, tingling arms jumping involuntarily/ fasciculations, low blood pressure, Dysautonomia, nausea, erythema, pericardial effusion, chest pain, burning eyes, Pulsatile and tonal tinnitus, Inappetence, Severe pain in my neck, Severe pain in my back, Anxiety, Severe pain in Achilles tendons, pain in hip torso /joints, bone pain, Sinus pressure, Cardiac edema, arms jumping involuntarily out of my hospital bed and "felt horrible and I knew something wasn't right this was the first of five ER trips" and serious (due to Hospitalization and medically significant) events of pericardial effusion, Adrenaline dumps a blood clot and neuropathies. The events occurred 12 hs. after the mRNA-1273 vaccine booster dose administration (the dose number was not provided). The outcome of the events was reported as recovering. As per the patient, who was the reporter, no definitive diagnosis was provided except for, considering the timeline, a reaction to the booster. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a literature non-study case concerning a 50 year-old, female patient with no reported medical history except for being a lifelong athlete, who experienced the serious (due to hospitalization) unexpected events of Tachycardia, Dizzy, Severe gastrointestinal issues, Head, neck, arms, hands and body began tingling, difficulty breathing, tingling arms jumping involuntarily/ fasciculations, low blood pressure, Dysautonomia, nausea, erythema, pericardial effusion, chest pain, burning eyes, Pulsatile and tonal tinnitus, Inappetence, Severe pain in my neck, Severe pain in my back, Anxiety, Severe pain in Achilles tendons, pain in hip torso /joints, bone pain, Sinus pressure, Cardiac edema, arms jumping involuntarily out of my hospital bed and "felt horrible and I knew something wasn't right this was the first of five ER trips" and serious (due to Hospitalization and medically significant) events of pericardial effusion, Adrenaline dumps a blood clot and neuropathies. The events occurred 12 hs. after the mRNA-1273 vaccine booster dose administration (the dose number was not provided). The outcome of the events was reported as recovering. As per the patient, who was the reporter, no definitive diagnosis was provided except for, considering the timeline, a reaction to the booster. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.