Day 3 after booster got painful lymph node near left collarbone same side as shot next day very swollen; Day 3 after booster got painful lymph node near left collarbone same side as shot next day very swollen; Followed up with cardiologist next day, put me on heart monitor / Heart monitor showed spikes; 3 hours after booster got a severe headache; Heart rate, BP were extremely elevated; Heart rate, BP were extremely elevated; The patient received the third/booster dose of BNT162b2; Patient received both Pfizer vaccine and flu vaccine on 26Oct2021; Cardiologist thinks immune system amped up especially after getting flu shot the same day; All of it has caused a lot of anxiety; This is a spontaneous report received from a contactable reporter(s) (Other HCP). The reporter is the patient.  A 63 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 26Oct2021 13:00 (Lot number: FH8020) at the age of 63 years as dose 3 (booster), single for covid-19 immunisation at Pharmacy or Drug Store; influenza vaccine (FLU), administration date 26Oct2021 (Batch/Lot number: unknown). The patient had no relevant medical history. Concomitant medication(s) included: AUGMENTIN [AMOXICILLIN; CLAVULANIC ACID]; NASONEX. Past drug history included: Pepcid, reaction(s): "Known allergies: Pepcid", notes: Known allergies: Pepcid; Ampicillin, reaction(s): "Known allergies: Ampicillin", notes: Known allergies: Ampicillin; Keflex, reaction(s): "Known allergies: Keflex", notes: Known allergies: Keflex. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE; Lot Number: EL9262; Anatomical site: Left arm; Administration time: 13:00), administration date: 22Jan2021, when the patient was 62 years old, for COVID-19 immunisation; Bnt162b2 (DOSE 2, SINGLE; Lot Number: EL9266; Anatomical site: Right arm; Administration time: 15:00), administration date: 15Feb2021, when the patient was 62 years old, for COVID-19 immunisation. The following information was reported: IMMUNISATION (non-serious) with onset 26Oct2021 13:00, outcome "unknown", described as "The patient received the third/booster dose of BNT162b2";  PRODUCT USE ISSUE (non-serious) with onset 26Oct2021, outcome "unknown", described as "Patient received both Pfizer vaccine and flu vaccine on 26Oct2021"; HEADACHE (non-serious) with onset 26Oct2021 16:00, outcome "recovered with sequelae" (01Nov2021), described as "3 hours after booster got a severe headache"; HEART RATE INCREASED (non-serious), BLOOD PRESSURE INCREASED (non-serious) all with onset 26Oct2021 16:00, outcome "recovered with sequelae" (01Nov2021) and all described as "Heart rate, BP were extremely elevated"; HEART RATE ABNORMAL (non-serious) with onset 27Oct2021, outcome "recovered with sequelae" (01Nov2021), described as "Followed up with cardiologist next day, put me on heart monitor / Heart monitor showed spikes"; LYMPH NODE PAIN (non-serious) with onset 28Oct2021, outcome "recovering", LYMPHADENOPATHY (non-serious) with onset 29Oct2021, outcome "recovering" and all described as "Day 3 after booster got painful lymph node near left collarbone same side as shot next day very swollen"; IMMUNE SYSTEM DISORDER (non-serious) with onset 2021, outcome "recovered with sequelae" (2021), described as "Cardiologist thinks immune system amped up especially after getting flu shot the same day"; ANXIETY (non-serious) with onset 2021, outcome "recovered with sequelae" (2021), described as "All of it has caused a lot of anxiety". The events "3 hours after booster got a severe headache", "heart rate, bp were extremely elevated", "heart rate, bp were extremely elevated", "followed up with cardiologist next day, put me on heart monitor / heart monitor showed spikes", "day 3 after booster got painful lymph node near left collarbone same side as shot next day very swollen", "day 3 after booster got painful lymph node near left collarbone same side as shot next day very swollen", "cardiologist thinks immune system amped up especially after getting flu shot the same day" and "all of it has caused a lot of anxiety" were evaluated at the physician office visit and emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of lymph node pain, lymphadenopathy, immune system disorder.  Addition information: The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Prior to vaccination, was the patient diagnosed with COVID-19 was reported as no. Since the vaccination, has the patient been tested for COVID-19 was reported as yes. The patient is a known allergies Keflex, Ampicillin, Pepcid. Did the adverse event result in any of the following was reported as Doctor or other healthcare professional office/clinic visit. Did the adverse event result in any of the following was reported as Emergency room/department or urgent care. It was reported that there were 4 movable pea sized nodes which went down to 1 large pea size node in 5 days but still remains and has decreased but can still feel it at times.  No follow-up attempts are possible; information about lot/batch number cannot be obtained.