my arm felt really heavy, like it weighed a thousand pounds; I ended up getting the worst itching from the top of my head all the way to my ankles where I was ripping my skin apart; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 78-year-old female patient received bnt162b2 (BNT162B2), on 17Feb2021 as dose 2, single (Lot number: EN6200) at the age of 78 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "eczema" (unspecified if ongoing), notes: I had eczema in one ear for like 30 years; "Osteoporosis" (unspecified if ongoing), notes: not take anything for that; "she has nodules in her lungs" (ongoing); "emphysema" (unspecified if ongoing); "asthma" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: bnt162b2 (Dose: 1, Lot: EL9262, Expiration: unknown, NDC: unknown, Given in right arm), administration date: 27Jan2021, when the patient was 78-year-old, for Covid-19 Immunization. The following information was reported: LIMB DISCOMFORT (non-serious) with onset 17Feb2021, outcome "recovered" (18Feb2021), described as "my arm felt really heavy, like it weighed a thousand pounds"; PRURITUS (non-serious) with onset 2021, outcome "not recovered", described as "I ended up getting the worst itching from the top of my head all the way to my ankles where I was ripping my skin apart". The events "i ended up getting the worst itching from the top of my head all the way to my ankles where i was ripping my skin apart" and "my arm felt really heavy, like it weighed a thousand pounds" required physician office visit. Therapeutic measures were taken as a result of pruritus, limb discomfort. Additional information: About 5 or 6 in the evening after the second shot, her arm felt really heavy, like it weighed a thousand pounds. It did not hurt and was not red. It lasted overnight and then it was gone the next morning. She took a Tylenol and slept the whole night and the next morning she was fine. After the second dose the patient ended up getting the worst itching from the top of her head all the way to her ankles where she was ripping her skin apart. It felt like she had a hundred thousand red ants biting her from her head to her ankles. It got worst over the past 3 years. She had had 13 shots in the past 3 years and it may be related to the combination of all these shots over the past 3 years; some were flu shots, some b12 shots. B12 shots can cause dermatitis. She was also on Dupixent (2 shots at a time, one on each thigh) for her skin now. Dupixent was started with two shots on 19May2023 and then now it was one shot which she gave herself, every two weeks. The Dupixent shots really hurt. She had to go on a steroid taper for the itching - she was on 20mg x 4 days, 10mg x 3 days, then 5mg x 5 days. That was the only thing that stopped the violent itching. Even now with the Dupixent, her forehead and her midriff still itches. This is more than eczema. She had eczema in one ear for like 30 years. This was definitely a side effect of all the shots she had been getting for the past 3 years. The patient received the third dose of Pfizer COVID-19 vaccine on 21Oct2021 (Lot: FIT8021 or FIT8027), fourth dose on 07Apr2022 (lot 1J9943), fifth dose on 22Nov2022 (Lot: GJ5342). She has been getting CT scans once a year since she has nodules in her lungs. Took one CT scan in Mar2023 and one in Jun2023 since the doctor found in her lower right lobe, what he thought may be some sort of infection or pneumonia and she was given antibiotics.