Very strong allergic reaction; Itchy eyes; This is a spontaneous report from a contactable consumer (patient). A 76-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Lot number: EN6207), via an unspecified route of administration in left arm on 14Mar2021 at 17:00 (at the age of 76-year-old) as dose 1, single for COVID-19 immunisation. Medical history included antidepressant from an unknown date and unknown if ongoing, to go to sleep (sleep disorder) from an unknown date and unknown if ongoing, blood pressure from an unknown date and unknown if ongoing. Concomitant medications included bupropion taken for antidepressant, start and stop date were not reported; ascorbic acid, calcium pantothenate, cyanocobalamin, inositol, lysine hydrochloride, nicotinamide, pyridoxine hydrochloride, riboflavin, thiamine hydrochloride (VIVARIN [ASCORBIC ACID;CALCIUM PANTOTHENATE;CYANOCOBALAMIN;INOSITOL;LYSINE HYDROCHLORIDE;NICOTINAMIDE;PYRIDOXINE HYDROCHLORIDE;RIBOFLAVIN;THIAMINE HYDROCHLORIDE]) taken because she does not drink coffee (Over the counter caffeine), start and stop date were not reported; levothyroxine sodium (SYNTHROID) taken for an unspecified indication, start and stop date were not reported; quetiapine taken for an unspecified indication, start and stop date were not reported; alprazolam taken for sleep disorder, start and stop date were not reported; dexamfetamine sulfate (DEXTROAMPHETAMINE) taken for an unspecified indication, start and stop date were not reported; desvenlafaxine taken for an unspecified indication, start and stop date were not reported; amlodipine taken for blood pressure abnormal, start and stop date were not reported. This consumer reported they were administered the first dose of the Pfizer-BioNTech COVID-19 Vaccine shot "yesterday" (Sunday) afternoon at their local pharmacy. When they came home last night they developed very, very itchy eyes which has gotten considerably worse. They took an allergy medication; Claritin they think it was called and has been putting in eye drops but the itching does not seem to be going away. She has allergies to hay fever. They called to ask if there was anything they can do for this event. She knows on the thing that was said to watch out if you have any allergies. She assumed that meant severe allergies like if you have anaphylactic reactions to something like Penicillin. She has non-severe allergies to things like hay fever and ragweed things like that. She had a very strong allergic reaction after that first dose. She called to ask about if she should get the second dose of Pfizer-BioNTech COVID-19 Vaccine related to this event because she was a little concerned. Very strong allergic reaction, onset around 14Mar2021 at 19:00. Further described as with her eyes being terribly itchy. She tried all of her usual allergy medications and drops and stuff and nothing really helped the event. By 15Mar2021 the event was gone, she recovered completely. The products involved were Claritin and Visine eye drops. Claritin, Lot: She reported it looks like CV01ADW, she thought the last character was a W. Expiry: Apr2021. UPC: Unknown, she does not have the box, cannot make out the bunch of numbers on the packaging otherwise. Visine eye drops, Lot/UPC/Expiry: Unknown, caller does not have product with her at the time of the call. Pfizer-BioNTech COVID-19 Vaccine initially mentioned when Lot/Expiry queried that she did not know how much she can read the CDC vaccine record card; but was able to provide Lot. NDC/Expiry: Unknown, this was not on the CDC vaccine record card. Regarding concomitant products caller reported she takes antidepressants but did not clarify further what other products were antidepressants than Bupropion. Therapeutic measures were taken as a result of itchy eyes. The outcome of Itchy eyes was resolved on an unknown date and very strong allergic reaction was resolved on 15Mar2021.  No follow up attempts are possible. No further information is expected.