Swollen lymph node arm pit of the right arm. Very painful; Swollen lymph node arm pit of the right arm. Very painful; Right arm swelled; Burning sensation; Elevated resting heart rate of 105; itchy/  itchy around my neck; red rash; This spontaneous case was reported by a consumer and describes the occurrence of PERIPHERAL SWELLING (Right arm swelled), BURNING SENSATION (Burning sensation), HEART RATE INCREASED (Elevated resting heart rate of 105), PRURITUS (itchy/  itchy around my neck) and ERYTHEMA (red rash) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 051C21A and 040C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Non-smoking, non-drinking, physically active. History of allergies to penicillin, and Erythromycin. Allergies to 37 indoor and outdoor allergens.  Previously administered products included for an unreported indication: BENADRYL ALLERGY [DIPHENHYDRAMINE HYDROCHLORIDE] until 30-Jul-2021. Concurrent medical conditions included Penicillin allergy, Allergy to antibiotic (Allergy to Erythromycin), Allergy to molds (Allergies to Homodendrum), Alternaria infection (Allergy to Alternaria), Allergy to molds (Allergy to Helminsthosporium), Allergy to molds (Allergy to Fusarium), Allergy to molds (Allergy to Stemphylium), Allergy to molds (Allergy to Curvularia), Allergy to molds (Allergic to Pullaria), Allergy to molds (Allergic to Aspergillus), Allergy to molds (Allergic to Epicoccum), Dust allergy (Allergic to Dust mites), Allergy to animals (Allergic to Dogs), Allergy to animals (Allergic to Cats), Allergy to feathers (Allergy to cockroaches), Allergy to insect sting, Grass allergy, Allergy to plants (Allergic to Sorrel plant), Ragweed allergy, Allergy to plants (Allergic to English Plantain), Allergy to plants (Allergic to Lamb's Quarters), Allergy to plants (Allergic to Pigweed), Allergy to plants (Allergic to Cockelbur weed plant), Nettle rash (Allergic to Nettle weed plant), Allergy to plants (Allergic to Palm Trees), Allergy to plants (Allergic to Melaleuca), Allergy to plants (Allergic to Australian pine), Allergy to plants (Allergic to White Pine), Allergy to plants (Allergic to Live Oak), Allergy to plants (Allergic to Red Cedar Elm), Allergy to plants (Allergic to Maple plant), Allergy to plants (Allergic to Ash Cottonwood) and Allergy to plants (Allergic to Brazilian Pepper tree). Concomitant products included BUDESONIDE (RHINOCORT [BUDESONIDE]) for an unknown indication.   On 22-Jun-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 31-Jul-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Jun-2021 at 6:20 AM, the patient experienced PERIPHERAL SWELLING (Right arm swelled), BURNING SENSATION (Burning sensation), HEART RATE INCREASED (Elevated resting heart rate of 105), PRURITUS (itchy/  itchy around my neck) and ERYTHEMA (red rash). On 30-Jun-2021 at 8:20 AM,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced AXILLARY PAIN (Swollen lymph node arm pit of the right arm. Very painful) and LYMPHADENOPATHY (Swollen lymph node arm pit of the right arm. Very painful). The patient was treated with IBUPROFEN, PSEUDOEPHEDRINE HYDROCHLORIDE (ADVIL FLU & BODY ACHE) at an unspecified dose and frequency. On 04-Jul-2021, AXILLARY PAIN (Swollen lymph node arm pit of the right arm. Very painful) and LYMPHADENOPATHY (Swollen lymph node arm pit of the right arm. Very painful) had resolved. At the time of the report, PERIPHERAL SWELLING (Right arm swelled), BURNING SENSATION (Burning sensation), HEART RATE INCREASED (Elevated resting heart rate of 105), PRURITUS (itchy/  itchy around my neck) and ERYTHEMA (red rash) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Heart rate: high (High) Heart rate running in low 100's.         Patient treated the side effects with Benadryl ( Diphenhydramine Hydrochloride ) after taking the vaccine. The rash on the arm went away in few hours. Patient took Advil ( Ibuprofen ) for the lymph node discomfort and elevated Heart rate. Heart rate still continues to be elevate than normal until today.   This case was linked to MOD-2021-272229 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 01-Aug-2021: Follow up report received on 01 Aug 2021, Added medical history, concomitant medications and events.