Stroke symptoms; hearing impaired; Fever; Pounding heart; Difficulty breathing; Malaise; Weakness/Weakness in upper chest; Rash appeared upper arms, chest, and upper back; Diarrhea; Stomach upset; Itchy; Fatigue/extreme fatigue; Rapid heart beats; Joint pain everywhere/Joint ache (all), wrist,ankle,knee,thigh; Difficulty swallowing; Bloody nose-very bad one; Bad/Very bad 1st night; Headaches/Woke up with headache in back of my head; Vertigo (room spinning); Joint aches- all wrist, ankle, knee, thigh etc; Scary; Difficulty walking/Winded walking up step/hard to mount stairs; Threw up mucous; Constant phlegm drip; Excessive white mucous/heavy mucous; Coughing spasms and heaving; elevated blood pressure; Joint ache (all), wrist,ankle,knee,thigh; The initial safety information received was reporting only non-serious adverse drug reactions, Upon receipt of follow-up information on 15Feb2022, this case now contains serious adverse reaction. Information processed together  This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 79 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in deltoid left, administration date 10Mar2021 11:10 (Lot number: EN6206, Expiration Date: 30Jun2021) at the age of 79 years as dose 2, 0.3 ml single for covid-19 immunisation. Relevant medical history included: "asthma" (ongoing), notes: History of asthma for many years; "allergies: Iodine" (unspecified if ongoing); "Right arm post surgery", start date: Mar2020 (unspecified if ongoing); "breast cancer", start date: 2015 (ongoing), notes: 2015,2017, 2020. R&G biopsy was 23Sep2021; "left breast Lumpectomy", start date: 03May2020 (unspecified if ongoing), notes: 1 year before incidents; "wrist veins left", start date: Feb2020 (unspecified if ongoing); "vein", start date: Jun2020 (unspecified if ongoing); "history of clots" (unspecified if ongoing); "history of phlebitis" (unspecified if ongoing); "Allergies: Tetracycline" (unspecified if ongoing); "Severe swelling" (unspecified if ongoing), notes: Tetracycline: Severe swelling; "acute abdominal pain" (unspecified if ongoing), notes: Tetracycline: lymph gland pooling, acute abdominal pain; "diarrhoea" (unspecified if ongoing), notes: Tetracycline: diarrhoea. The patient did not have a cancer diagnosis when 2 shots were given. She was not taking any chemo drugs. She did not have any radiation treatments. She was not taking any prescription drugs when I had adverse reactions to the shots. There were no concomitant medications. Past drug history included: Percocet, reaction(s): "allergies: percocet"; Fosamax, reaction(s): "Allergies: Fosamax"; Augmentin for Hives, reaction(s): "Reaction: hives"; Biaxin, reaction(s): "Reaction: Altered heart rate"; Allergies: epinephrine, reaction(s): "allergies: Epinephrine"; Allergies: gadolinium-containing contrast media, reaction(s): "allergies: gadolinium-containing contrast media"; Allergies: oxycodone, reaction(s): "allergies: Oxycodone"; Allergies: oxycodone hcl, reaction(s): "allergies: Oxycodone HCL"; Allergies: clavulanate, reaction(s): "allergies: clavulanate"; Propoxyphene hcl, reaction(s): "allegies: Propoxyphene HCL"; Allergies: simvastatin, reaction(s): "allergies: Simvastatin". Vaccination history included: Bnt162b2 (First dose: 0.3ml, Time: 11:30 AM, Route: intramuscular, Lot no: Pfizer Em9810, Anatomical location: Right deltoid), administration date: 17Feb2021, when the patient was 79 years old, for COVID-19 immunization, reaction(s): "Rash upper back and chest", "Difficulty breathing", "Headaches", "Malaise", "weakness/weakness in upper chest", "constant phlegm drip", "Excessive white mucous/sleepery,gross, huge quantity of mucous", "coughing spasms and heaving", "Elevated Blood Pressure", "Extreme fatigue", "Joint aches,Wrist aches,Ankle aches, Knee aches", "Thigh aches", "Pounding heart", "Difficulty walking/Winded walking up step", "Scary", "threw up mucos", "Winded walking up steps", "itchy", "No appetite", "Sick", "Sleeping", "Stomach upset", "Severe acute respiratory syndrome", "Covid-19", "Digestive- Sick", "Body went into heaving spasm"; Flu shot (Since 30Oct2019 I have never had another flu shot took.), administration date: 30Oct2021, when the patient was 77 years old, reaction(s): "Itchy", "Rash on upper body,chest, back and arms", "Fever/Fever 150", "Racing feeling in body up all night", "Left arm burning/Burning up", "Sore throat", "Fatigue", "malaise", "Diarrhea", "Stomach pains", "Joint pain"; Flu shot (Since 30Oct2019 I have never had another flu shot took.), reaction(s): "Achy joints", "nausea". The following information was reported: CEREBROVASCULAR ACCIDENT (medically significant), outcome "unknown", described as "Stroke symptoms"; VERTIGO (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Vertigo (room spinning)"; DYSPNOEA (non-serious) with onset 12Mar2021, outcome "not recovered", described as "Difficulty breathing"; DYSPHAGIA (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Difficulty swallowing"; EPISTAXIS (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Bloody nose-very bad one"; FEELING ABNORMAL (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Bad/Very bad 1st night"; HEADACHE (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Headaches/Woke up with headache in back of my head"; MALAISE (non-serious) with onset 12Mar2021, outcome "unknown", described as "Malaise"; ASTHENIA (non-serious) with onset 12Mar2021, outcome "unknown", described as "Weakness/Weakness in upper chest"; PRODUCTIVE COUGH (non-serious) with onset 2021, outcome "unknown", described as "Constant phlegm drip"; SECRETION DISCHARGE (non-serious) with onset 2021, outcome "unknown", described as "Excessive white mucous/heavy mucous"; COUGH (non-serious) with onset 2021, outcome "unknown", described as "Coughing spasms and heaving"; PAIN (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Joint aches- all wrist, ankle, knee, thigh etc"; PALPITATIONS (non-serious) with onset 12Mar2021, outcome "unknown", described as "Pounding heart"; FEAR (non-serious) with onset 2021, outcome "unknown", described as "Scary"; GAIT DISTURBANCE (non-serious) with onset 2021, outcome "unknown", described as "Difficulty walking/Winded walking up step/hard to mount stairs"; VOMITING (non-serious) with onset 2021, outcome "unknown", described as "Threw up mucous"; RASH (non-serious) with onset 12Mar2021, outcome "unknown", described as "Rash appeared upper arms, chest, and upper back"; DIARRHOEA (non-serious) with onset 12Mar2021, outcome "unknown", described as "Diarrhea"; ABDOMINAL DISCOMFORT (non-serious) with onset 12Mar2021, outcome "unknown", described as "Stomach upset"; PRURITUS (non-serious) with onset 12Mar2021, outcome "unknown", described as "Itchy"; FATIGUE (non-serious) with onset 12Mar2021, outcome "unknown", described as "Fatigue/extreme fatigue"; HEART RATE IRREGULAR (non-serious) with onset 12Mar2021, outcome "unknown", described as "Rapid heart beats"; ARTHRALGIA (non-serious) with onset 11Mar2021 03:30, outcome "unknown", described as "Joint pain everywhere/Joint ache (all), wrist,ankle,knee,thigh"; HYPERTENSION (non-serious) with onset 2021, outcome "unknown", described as "elevated blood pressure"; PAIN IN EXTREMITY (non-serious) with onset 2021, outcome "unknown", described as "Joint ache (all), wrist,ankle,knee,thigh"; HYPOACUSIS (non-serious), outcome "unknown", described as "hearing impaired"; PYREXIA (non-serious), outcome "unknown", described as "Fever". The patient underwent the following laboratory tests and procedures: blood pressure measurement: (2021) high; computerised tomogram: (10Nov2021) unknown results, notes: chest WO contrast; echocardiogram: (24Mar2021) unknown results, notes: transthoracic; investigation: (13May2021) unknown results; (13May2021) unknown results; (24Mar2021) unknown results; sars-cov-2 test: (2021) unknown result.; Sender's Comments: Linked Report(s) : PFIZER INC-202101515029 Same patient and drug, different dose number and events