Breathing difficulty and felt that her heart was pumping in her chest, and this was making it hard for her to walk, after first vaccine.; Breathing difficulty and felt that her heart was pumping in her chest, and this was making it hard for her to walk, after first vaccine.; Chest Pain under left breast, after first vaccine; This is a spontaneous report from a contactable consumer (patient's husband). This consumer reported for his wife that a 64-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Formulation: Solution for injection, Lot number: EN6203, Expiration Date: unknown) via an unspecified route of administration in right arm on 05Mar2021 as 1st dose, single dose for COVID-19 immunization. Additional Vaccines was not administered on same date of the Pfizer Suspect. No other vaccines have been administered within 4 weeks prior to the first administration date of the suspect vaccine. Patient did not had AE(s) following prior vaccinations. Medical history included ongoing high blood pressure from Apr2020, ongoing High Blood cholesterol increased from Jan2020, ongoing asthma from 2020, ongoing Hepatic steatosis, allergies to multiple medications Codeine: headache Contrast medium: flushing, itchy skin. previously took Fexofofenadine HCL: unknown effect. Iodine: skin reaction. Lansoprazole: skin rash Latex: skin rash. Lisinopril: itchy tongue. Metoprolol Fumarate: headache, nausea. Oxycodone: nausea and headache. Ongoing concomitant medication included (ASPIRIN) at 81 mg oral; colecalciferol (VITAMIN D3) from Mar2019 at 2000 iU, once a day oral; simvastatin (ZOCOR) taken for blood cholesterol increased from Jan2020 at 10 mg, once a day oral; carvedilol taken for blood pressure measurement from Apr2020 via oral at 3.125 mg, twice a day; olmesartan medoxomil (BENICAR) taken for blood pressure measurement from Apr2020 at oral 25 mg, twice a day; fluticasone propionate, salmeterol xinafoate (ADVAIR) taken for asthma from Apr2020 at 250/50, inhalation. In Mar 2021, The patient experienced breathing difficulty and felt that her heart was pumping in her chest and this was making it hard for her to walk and the next week chest pain under left breast, a couple of days after first vaccine around 11Mar2021 or 12Mar2021 as the chest pain would start again when she was walking and she occasionally feels a twinge, reclarified, and she had to go to the emergency room and get evaluated. Patient went to the emergency room had an EKG and a troponin blood test, which were all negative on 29Apr2021. The patient underwent lab tests and procedures which included cardiac stress test: normal on 21Mar2021, computerised tomogram: normal for age, enlarged spleen noted on 29Apr2021, electrocardiogram: normal on 19Mar2021, magnetic resonance imaging: enlarged spleen on 27Apr2021, troponin: normal on 19Mar2021. CT Scan was done first then the MRI was done after the CT Scan. she was still had chest pain, and the doctor thought, it could be from the vaccine, since all the tests were normal. It was reported that as about 5-7 days after the shot, around the 10Mar2021 or 11Mar2021 in afternoon and it was isolated to the same day as it started. After she was in the emergency room and saw the cardiologist, and after the recent reports of the vaccine's effected with the heart, the cardiologist thought the vaccine caused effects. Patient had the second vaccine, and then reclarified, all of the symptoms went away. Patient received second dose of vaccine on 26Mar2021 around noon (Lot: ER8730, expiration: unknown) via unspecified route of administration in right arm. After second vaccine patient had a fever, of 102 degrees and felt exhausted for two days, after the second vaccine on 26Mar2021, Enlarged spleen on 29Apr2021. Fever lasted about a day and a half later. Feeling exhausted lasted for about a week. Facility was hospital, off site location. It was reported that patient also saw a liver specialist, and that doctor, wanted her effects, to be reported. Because all of the heart tests were negative, the liver specialist ordered an MRI elastograph of the liver and spleen and that test showed she had an enlarged spleen. The outcome for the event Breathing difficulty and felt that her heart was pumping in her chest, and this was making it hard for her to walk, after first vaccine was recovered in Mar2021 and chest pain unknown, Chest Pain under left breast, after first vaccine and had an EKG and a Troponin blood test, which were all negative was unknown.  Follow up attempts are needed. Further information has been requested.