blood work came back positive for Rheumatoid Arthritis/inflammation of hands; I was diagnosed with Uveitis with Iritis; I started to have eye issues and could not see; Inflammation of the eyes and hands; could not see; I was diagnosed with Uveitis with Iritis; felt like I was getting the flu; body aches; headache; chills; This spontaneous case was reported by a consumer and describes the occurrence of RHEUMATOID ARTHRITIS (blood work came back positive for Rheumatoid Arthritis/inflammation of hands) and UVEITIS (I was diagnosed with Uveitis with Iritis) in a 40-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 015N20A and 013L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included HYDROXYCHLOROQUINE SULFATE (PLAQUENIL [HYDROXYCHLOROQUINE SULFATE]) for an unknown indication.   On 19-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 21-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 21-Feb-2021, the patient experienced INFLUENZA LIKE ILLNESS (felt like I was getting the flu), MYALGIA (body aches), HEADACHE (headache) and CHILLS (chills). On an unknown date, the patient experienced RHEUMATOID ARTHRITIS (blood work came back positive for Rheumatoid Arthritis/inflammation of hands) (seriousness criterion medically significant), UVEITIS (I was diagnosed with Uveitis with Iritis) (seriousness criterion medically significant), OCULAR DISCOMFORT (I started to have eye issues and could not see), EYE INFLAMMATION (Inflammation of the eyes and hands), VISUAL IMPAIRMENT (could not see) and IRITIS (I was diagnosed with Uveitis with Iritis). The patient was treated with PREDNISONE at an unspecified dose and frequency. At the time of the report, RHEUMATOID ARTHRITIS (blood work came back positive for Rheumatoid Arthritis/inflammation of hands), UVEITIS (I was diagnosed with Uveitis with Iritis), OCULAR DISCOMFORT (I started to have eye issues and could not see), EYE INFLAMMATION (Inflammation of the eyes and hands), VISUAL IMPAIRMENT (could not see), IRITIS (I was diagnosed with Uveitis with Iritis) and INFLUENZA LIKE ILLNESS (felt like I was getting the flu) outcome was unknown and MYALGIA (body aches), HEADACHE (headache) and CHILLS (chills) had resolved.            Concomitant medication details was provided as patient is taking eye dilating eye drops, prednisone eye drops and steroid taper. Patient had flu again after 5 days of vaccine. Patient went to emergency room due to eye issues. Then went to ophthalmologist and ordered for blood work to check autoimmune source and recommended to visit rheumatologist. Laboratory details was mentioned as on an unknown date patient took blood work which came back as positive for ANA antibodies where were negative for patient before Moderna vaccine. Additional to that patient done additional blood work and chest X ray on an unknown date where blood work came back positive for rheumatoid arthritis.  Treatment information was mentioned as patient provided with eye dilating drops.  Company comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  However, more information is required for further assessment.   This case was linked to MOD-2021-290955 (Patient Link).   Reporter did not allow further contact; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  However, more information is required for further assessment.