Hallucination; Delirious; optic neuritis; lost vision; lost speech/could not talk; anxiety; swelling thyroid; stomach pain; constipation; depression worsened; nerve pain; migraines; back pain; congestion,stuffy nose; confusion; falling; losing balance; more memory loss; couldn't swallow; weakness; tingling; scarred; Could not write; sore arm; head pain/ Headaches; This spontaneous case was reported by a consumer and describes the occurrence of HALLUCINATION (Hallucination), DELIRIUM (Delirious), OPTIC NEURITIS (optic neuritis) and BLINDNESS (lost vision) in a 55-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history provided by the reporter.  Concomitant products included OCRELIZUMAB (OCREVUS), CLONAZEPAM (KLONOPIN), LEVOTHYROXINE, OMEPRAZOLE, LINACLOTIDE (LINZESS), BUPROPION HYDROCHLORIDE (WELLBUTRIN), DULOXETINE, GABAPENTIN (NEURONTIN), EZETIMIBE (ZETIA), SUMATRIPTAN, FREMANEZUMAB (AJOVY [FREMANEZUMAB]), PARACETAMOL (TYLENOL), IBUPROFEN (ADVIL [IBUPROFEN]), MOMETASONE FUROATE (FLONASE [MOMETASONE FUROATE]) and MACROGOL 3350 (MIRALAX) for an unknown indication.    On 04-Mar-2021, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced HALLUCINATION (Hallucination) (seriousness criterion medically significant), DELIRIUM (Delirious) (seriousness criterion medically significant), OPTIC NEURITIS (optic neuritis) (seriousness criterion medically significant), BLINDNESS (lost vision) (seriousness criterion medically significant), APHASIA (lost speech/could not talk), ANXIETY (anxiety), GOITRE (swelling thyroid), ABDOMINAL PAIN UPPER (stomach pain), CONSTIPATION (constipation), DEPRESSION (depression worsened), NEURALGIA (nerve pain), MIGRAINE (migraines), BACK PAIN (back pain), NASAL CONGESTION (congestion,stuffy nose), CONFUSIONAL STATE (confusion), FALL (falling), BALANCE DISORDER (losing balance), AMNESIA (more memory loss), DYSPHAGIA (couldn't swallow), ASTHENIA (weakness), PARAESTHESIA (tingling), SCAR (scarred), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (Could not write), PAIN IN EXTREMITY (sore arm) and HEADACHE (head pain/ Headaches). At the time of the report, HALLUCINATION (Hallucination), DELIRIUM (Delirious), OPTIC NEURITIS (optic neuritis), BLINDNESS (lost vision), APHASIA (lost speech/could not talk), ANXIETY (anxiety), GOITRE (swelling thyroid), ABDOMINAL PAIN UPPER (stomach pain), CONSTIPATION (constipation), DEPRESSION (depression worsened), NEURALGIA (nerve pain), MIGRAINE (migraines), BACK PAIN (back pain), NASAL CONGESTION (congestion,stuffy nose), CONFUSIONAL STATE (confusion), FALL (falling), BALANCE DISORDER (losing balance), AMNESIA (more memory loss), DYSPHAGIA (couldn't swallow), ASTHENIA (weakness), PARAESTHESIA (tingling), SCAR (scarred), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (Could not write), PAIN IN EXTREMITY (sore arm) and HEADACHE (head pain/ Headaches) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood cholesterol: high (High) High cholesterol.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       It was reported that on an unknown date patient experienced zero antibiotics.  No treatment information was given.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.