Back became sore towards the kidney area; Right calf into the ankle started being irritated, swollen, and itchy; Tingling and irritation in his ankle; Tingling and irritation in his ankle; Right calf into the ankle started being irritated, swollen, and itchy; Right calf into the ankle started being irritated, swollen, and itchy; Lower back pain; Right kidney pain for 2 months; Swelling in ankles; Swelling in leg; This spontaneous case was reported by a consumer and describes the occurrence of PARAESTHESIA (Tingling and irritation in his ankle), MUSCULOSKELETAL DISCOMFORT (Tingling and irritation in his ankle), FLANK PAIN (Back became sore towards the kidney area), LIMB DISCOMFORT (Right calf into the ankle started being irritated, swollen, and itchy) and PERIPHERAL SWELLING (Right calf into the ankle started being irritated, swollen, and itchy) in a 60-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 019b21a) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 31-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 31-Mar-2021, the patient experienced LIMB DISCOMFORT (Right calf into the ankle started being irritated, swollen, and itchy), PERIPHERAL SWELLING (Right calf into the ankle started being irritated, swollen, and itchy), BACK PAIN (Lower back pain), RENAL PAIN (Right kidney pain for 2 months), JOINT SWELLING (Swelling in ankles) and PERIPHERAL SWELLING (Swelling in leg). On 02-Apr-2021, the patient experienced PARAESTHESIA (Tingling and irritation in his ankle) and MUSCULOSKELETAL DISCOMFORT (Tingling and irritation in his ankle). On 31-May-2021, the patient experienced PRURITUS (Right calf into the ankle started being irritated, swollen, and itchy). On an unknown date, the patient experienced FLANK PAIN (Back became sore towards the kidney area). The patient was treated with Physical therapy for Musculoskeletal discomfort; Physical therapy for Flank pain; Physical therapy for Limb discomfort; Physical therapy for Back pain and Physical therapy for Joint swelling. At the time of the report, PARAESTHESIA (Tingling and irritation in his ankle), MUSCULOSKELETAL DISCOMFORT (Tingling and irritation in his ankle), FLANK PAIN (Back became sore towards the kidney area), LIMB DISCOMFORT (Right calf into the ankle started being irritated, swollen, and itchy), PERIPHERAL SWELLING (Right calf into the ankle started being irritated, swollen, and itchy) and PRURITUS (Right calf into the ankle started being irritated, swollen, and itchy) had not resolved and BACK PAIN (Lower back pain), RENAL PAIN (Right kidney pain for 2 months), JOINT SWELLING (Swelling in ankles) and PERIPHERAL SWELLING (Swelling in leg) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       On an unknown date, the patient went to local hospital to have his leg scanned for blood clots that came back negative. On an unknown date, patient received 3  physical therapy test for muscles that came back negative. Patient stated that he was going to receive another test to make sure he is not subject to a stroke.    The patient was advised by his physician not to receive the second Moderna vaccine.  Concomitant medication included blood pressure (unspecified) No treatment information was reported.   Most recent FOLLOW-UP information incorporated above includes: On 01-Jul-2021: Lab information was added to inarrative supplement.Events dates and details were added. On 07-Aug-2021: Follow up information received on 07-AUG-2021 included no new information.