Shot #2 he was quite under the weather for a day and a half.; This is a spontaneous report received from contactable reporter(s) (Nurse) from medical information team, Program ID. The reporter is the patient.  A 68-year-old male patient received BNT162b2 (BNT162B2), on 04Mar2021 as dose 2, single (Lot number: EN6198) at the age of 67 years for covid-19 immunisation. The patient's relevant medical history included: "heart issue/weak heart" (unspecified if ongoing); "diastolic disfunction" (unspecified if ongoing), notes: diastolic disfunction; "blood pressure" (unspecified if ongoing), notes: blood pressure medications; "smoking" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (lot EN9581, he may have had chills that night), administration date: 11Feb2021, when the patient was 67-year-old, for COVID-19 immunization, reaction(s): "chills that night"; Vaccine (had tons of shots); Plague vaccine (He got a little reaction because he got 5 in 1 shot and they were all different, the plague, typhoid the whole 9 years), reaction(s): "Reaction"; Typhoid vaccine (He got a little reaction because he got 5 in 1 shot and they were all different, the plague, typhoid the whole 9 years), reaction(s): "Reaction"; Flu shots, reaction(s): "gets a little chill", "sensitive". The following information was reported: MALAISE (non-serious) with onset 2021, outcome "unknown", described as "Shot #2 he was quite under the weather for a day and a half.". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Relays that the caller has had the 2 original shots of Pfizer COVID 19 vaccine and also booster doses. He had progressively strong response from each shot and the last dose caused him to be in bed 3 days and he didn't feel good for about a week. It was reported that he was quite under the weather for a day and a half. Caller had questions about Paxlovid and side effects but didn't mention if he was prescribed, they were general questions. Reporter details were provided as was a medic in the army and was licensed as an LPN, he went to specialty school in the army and got accredited and took the test. License is not currently active. With shot number 1 he was pretty asymptomatic, he may have had chills that night. Anytime he gets the flu shot he gets a little chill but it's never a problem. His wife tested positive for COVID and was asymptomatic. He never tested positive and he has been exposed a couple other times and if he ever had it was very mild or he was asymptomatic. One more caveat with Paxlovid, he takes some medication for his heart, for weak heart, diastolic disfunction. Last November he had catheter and they installed in the aortic well, it's an artificial valve they put in through a catheter through the femoral artery. He was in and out of the hospital and was there 1 night. They have not used this on younger people, he had aortic stenosis, an occlusion causing problems. He feels good but it sounds crazy, but he did hear there were interactions between some heart medications and Paxlovid and is not sure if they are rumor. He takes a couple of different blood pressure medications. He wouldn't have any trouble not using them for a week, he doesn't know. AE did not require a visit to Emergency Room and Physician Office. Prior vaccinations within 4 weeks was none. Family medical history was none.