Chest was hurting; Coughing up all kinds of stuff; ''Loosey-goosey" bowels; Feel horrible/feeling terrible; Asthma attack; This spontaneous case was received on 15-Oct-2022 reported by other non-health care professional via Agency (reference number: SEQW22- 04546) with additional information (being processed together) received on 17-Oct-2022 (reference number: SEQW22-04620) and concerned a female patient of an unreported age.  The patient's concurrent conditions included interstitial cystitis, issues with histamine releasing foods, asthma and allergy to aspirin. The patient recently found out she had a problem with histamines in foods and egg whites had histamines, so the patient did not eat egg whites at all. The patient could eat the yolk. The patient's concomitant medications included Albuterol (salbutamol) inhaler, used for asthma. The patient's historical vaccine included a flu shot and she usually did not feel good for a couple of days after a flu shot (see linked case 202205643).   On 14-Oct-2022, around 10:30-11:00 a.m., the patient was vaccinated with Fluad Quadrivalent (influenza vaccine inact sag 4v; dose, route of administration and anatomical location: not reported) for seasonal prevention of influenza. The batch number was not reported. The patient did not react right away after vaccination.   On 15-Oct-2022, around 1:30 in the morning, one day after receiving Fluad Quadrivalent, the patient experienced asthma attack and had to use her inhaler. The patient experienced "loosey-goosey" bowels and just felt horrible. The patient also ate some red cabbage last night. The patient had to be really careful with what she ate. She read red cabbage was a histamine liberator and she had issues with salicylates in food because she was allergic to Aspirin. But she did not feel weird after eating the cabbage. The patient's chest was hurting, and she was coughing up all kinds of stuff, but she did not have a cold. When she had these Reactions, it manifested in the chest.   At the time of initial reporting, the patient had not recovered from all events. She was still feeling terrible, and patient had a doctor's appointment scheduled.   The reporter assessed the events as related to the Fluad Quadrivalent. As reported, the patient thought she had a reaction to the shot. The patient usually did not feel good for a couple of days after she had the flu shot but had never had this kind of a reaction to it.   The case was assessed as non-serious.  This case is linked to 202205643 (the same patient).  Company comment: A patient of unreported age experienced asthmatic attack, chest pain, productive cough, diarrhoea, and abnormal feeling one day after receiving the suspect product Fluad Quadrivalent. Underlying medical history of interstitial cystitis, issues with histamine releasing foods (egg whites have histamines), and asthma contributed to the development of the events. Causality for the event asthmatic attack is assessed as not related, due to biological implausibility. For the remaining events, causality is assessed as possibly related, based on plausible temporal relationship.; Reporter's Comments: As reported, the patient thought she had a reaction to the shot. The patient usually did not feel good for a couple of days after she had the flu shot but had never had this kind of a reaction to it.; Sender's Comments: A patient of unreported age experienced asthmatic attack, chest pain, productive cough, diarrhoea, and abnormal feeling one day after receiving the suspect product Fluad Quadrivalent. Underlying medical history of interstitial cystitis, issues with histamine releasing foods (egg whites have histamines), and asthma contributed to the development of the events. Causality for the event asthmatic attack is assessed as not related, due to biological implausibility. For the remaining events, causality is assessed as possibly related, based on plausible temporal relationship.