Information has been received from a lawyer concerning an approx. 2 year old male who on 5/5/92 was vaccinated with MMRII and subsequently, experienced autism, autistic spectrum disorder, severe communication disorder, hyperactivity, sleep disturbance, grand mal convulsion, severe speech deterioration and lack of sense of danger. He presented with delayed speech at the age of 3 years and 3 months. The pt's developmental milestones were slightly delayed. He said his first words at 7 months but did not say any more words until he was 2 1/2 years old. He had 1 hospitalization for a possible convulsion. On exam, he was a healthy male with very poor eye contact, cardiovascular, respiratory and abdominal exams were all normal, both testes were palpable in the scrotum but small. Central nervous system exam revealed generalized hypotonia but reflexes were all present and plantars were flexor. On 12/18/98 he was examined by a pediatrician who said he had major problems with going to sleep and staying asleep. He had to sleep in his mother's bed. He had problems staying in his seat when his mother was taking him in the car and he had some temper tantrums at school. He continued to have problems with receptive language. The diagnoses were autistic spectrum disorder and developmental delay. The autism, aphasia, cognitive disturbance, developmental delay, grand mal convulsion, and speech disorder were considered "significant medical events". At the time of the report, the pt had not recovered from autism and possible autistic spectrum disorder and primary language disorder. Follow-up information indicated that on the day of vaccination 05/05/1992, the pt developed a temperature and during the month of May 1992 he had a loss of awareness, was distant and "stopped responding." In June 1992, the pt developed "sticky eyes" and conjunctivitis and in July 1992, he developed head banging and "spots with capillary flare on his right wrist, left forearm and on the face. In October 1992, the pt had a cold which lasted for 3 weeks. In November 1992, the pt had vomiting, loose stools, two days of lethargy, irritability and pyrexia. During November 1992 the pt also developed fine shaking movements and had two seizures with intermittent vomiting, diarrhea, limpness and "eyes whirling backwards." In March 1993, the pt had a "nappy dermatitis" and in April 1993, he had a "sticky eye." In September 1993, both of the pt's eyes were infected. In January 1994 the pt had "flat tracings" on a hearing test and in February 1994, his ears were "dull." In March 1994, he had limited vocabulary, episodes of acute otitis media following respiratory infections and a rash on his lower lip. In August 1994, the pt had poor eye contact and a primary receptive language disorder and signs of autistic spectrum were noted. In November 1994, the pt had a rash on his buttocks and legs. In December 1994, autistic spectrum disorder and "socialization" were diagnosed. In May 1995, the pt developed diarrhea for two days and in November 1995, he had vomiting and diarrhea. Upon internal review, autistic spectrum disorder and seizure were considered other important medical events. Sticky eyes, skin erythema, cold, respiratory infections, dermatitis, rahs, pyrexia and otitis media were considered incidental findings. No futher info is available. Follow-up information indicated the lot number reported, G0591, corresponds to an incorrect lot number.  Follow up on 03/28/2001: "Lot # for vaccine 1 is not provided."