a lot of physical problem; intestines are going crazy; gained 15 pounds in weight/gained in 15 pound; he woke up with face and ears looking like he had sun burn, and then his hands; and he had not been in the sun because it was February. It was sore and scaly and irritable/ Sores in hand and scalp, face and hand looks like sun burn/knuckles and hand; It was sore and scaly and irritable; lost a lot of muscles; oozing; It was sore and scaly and irritable; experienced severe water retention; my bowels are a mess; my skin is burning; I had sores on my knuckles; This spontaneous case was reported by a consumer and describes the occurrence of GENERAL PHYSICAL HEALTH DETERIORATION (a lot of physical problem), ABDOMINAL DISCOMFORT (intestines are going crazy), WEIGHT INCREASED (gained 15 pounds in weight/gained in 15 pound), RASH ERYTHEMATOUS (he woke up with face and ears looking like he had sun burn, and then his hands; and he had not been in the sun because it was February. It was sore and scaly and irritable/ Sores in hand and scalp, face and hand looks like sun burn/knuckles and hand) and SKIN IRRITATION (It was sore and scaly and irritable) in an 81-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 025L20A and 010M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 04-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 2 dosage form. On an unknown date, the patient experienced GENERAL PHYSICAL HEALTH DETERIORATION (a lot of physical problem), ABDOMINAL DISCOMFORT (intestines are going crazy), WEIGHT INCREASED (gained 15 pounds in weight/gained in 15 pound), RASH ERYTHEMATOUS (he woke up with face and ears looking like he had sun burn, and then his hands; and he had not been in the sun because it was February. It was sore and scaly and irritable/ Sores in hand and scalp, face and hand looks like sun burn/knuckles and hand), SKIN IRRITATION (It was sore and scaly and irritable), MUSCLE ATROPHY (lost a lot of muscles), SKIN WEEPING (oozing), SKIN EXFOLIATION (It was sore and scaly and irritable), FLUID RETENTION (experienced severe water retention), ABDOMINAL DISCOMFORT (my bowels are a mess), SKIN BURNING SENSATION (my skin is burning) and MYALGIA (I had sores on my knuckles). At the time of the report, GENERAL PHYSICAL HEALTH DETERIORATION (a lot of physical problem), ABDOMINAL DISCOMFORT (intestines are going crazy), WEIGHT INCREASED (gained 15 pounds in weight/gained in 15 pound), RASH ERYTHEMATOUS (he woke up with face and ears looking like he had sun burn, and then his hands; and he had not been in the sun because it was February. It was sore and scaly and irritable/ Sores in hand and scalp, face and hand looks like sun burn/knuckles and hand), SKIN IRRITATION (It was sore and scaly and irritable), MUSCLE ATROPHY (lost a lot of muscles), SKIN WEEPING (oozing), SKIN EXFOLIATION (It was sore and scaly and irritable), FLUID RETENTION (experienced severe water retention), ABDOMINAL DISCOMFORT (my bowels are a mess), SKIN BURNING SENSATION (my skin is burning) and MYALGIA (I had sores on my knuckles) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: everything seems fine (normal) everything seems fine. On an unknown date, Ultrasound scan: normal (normal) normal.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medication included Diuretics (unspecified).  After the second dose, the patient woke up with face and ears looking like had sun burn, and then his hands; and he had not been in the sun because it was February. It was sore and scaly and irritable. The patient used a cream to use (he does not remember the name), it gets better and then it comes back, like he got sun burnt again, it can't seem to heal up.  The cream makes it better, but it doesn't clear it up. He lost a lot of muscles. After the second Moderna COVID-19 injection I gained 15 pounds, experienced severe water retention," my bowels are a mess", my skin is burning. I had sores on my knuckles.  The patient was given a steroid shot because in his knuckles and hand, he had huge sores, that was oozing, and the steroid shot helped.   The patient had done some blood work (unspecified) and everything seems fine. No treatment information was provided.  Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   Most recent FOLLOW-UP information incorporated above includes: On 27-Aug-2021: follow-up received contains no new information; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.