swollen lymph; injection site and whole arm was so painful she couldn't sleep; injection site and whole arm was so painful she couldn't sleep; injection site and whole arm was so painful she couldn't sleep; tiredness; severe headache; Joint pain; loss of appetite; pain to the upper part of her left breast; swollen glands under her chin and on the left side of the neck/left armpit swollen; This is a spontaneous report from a contactable consumer (patient). A 65-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot Number: EL8982), via an unspecified route of administration on 04Feb2021 at 13:00 (at the age of 65-year-old), as dose 2, single in left arm for COVID-19 immunization at hospital. The patient's medical history included HRT (Hormone replacement therapy), low thyroid and surgical spine issues. Concomitant medications included levothyroxine sodium 88 ug (take once daily five days a week), taken for 23 years for hypothyroidism; progesterone 100 mg, one time per day, taken for 15 years for hormone replacement therapy; estradiol (DIVIGEL) 1 mg, one time per day, taken for 15 years for hormone replacement therapy, gabapentin 100 mg, take once daily at night, taken for 3 months, for spinal operation; start and stop dates were not reported. The patient previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot Number: 3302), via an unspecified route of administration on 14Jan2021 at 13:00 (at the age of 65-year-old), as single dose in left arm for COVID-19 immunization and experienced fever spikes like hot flashes, injection site and whole arm was so painful she couldn't sleep, severe headache, chills, fatigue, joint pain and loss of appetite. Patient did not receive other vaccine 4 weeks prior to COVID vaccine. On an unspecified date after second dose of vaccine, the patient experienced swollen lymph,  On 14Jan2021, after the first dose of vaccine, the patient's injection site and whole arm was so painful, but not red or swollen, she couldn't sleep, joint pain, which continued after second dose for 25 days; experienced tiredness; severe headache for 24 days; loss of appetite for 23 days. On 04Feb2021, after second dose of vaccine, the patient experienced swollen glands under her chin and on the left side of the neck/left armpit swollen. On 05Feb2021, 11 hours after second dose of vaccine, the patient experienced pain to the upper part of her left breast. Patient had visited her Healthcare professional and would be getting an ultrasound of her lymph nodes. Adverse events required a visit to physician or emergency room and no admission to the hospital. The clinical outcome of event swollen lymph was unknown. The clinical outcome of events severe headache, loss of appetite was resolved on 07Feb2021, the clinical outcome of events injection site and whole arm was so painful she couldn't sleep, joint pain was resolved on 08Feb2021. The clinical outcome of events tiredness; swollen glands under her chin and on the left side of the neck/left armpit swollen; and pain to the upper part of her left breast was resolving.  Follow-up attempts completed. No further information expected.