her liver was diffusely echogenic and fatty; her liver was diffusely echogenic and fatty; hepatic steatosis; fatigue; Alk phos raised; AST increased; ALT increased; gained 10 pounds; This is a spontaneous report from a contactable consumer or other non hcp (patient). A 64-year-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, solution for injection, Batch/Lot Number: EL0142) via an unspecified route of administration, administered in arm right on 13Jan2021 (at the age of 64-year-old) at dose 2, single, Administered between 9:00AM-9:30AM for covid-19 immunisation. Medical history and concomitant medications were not reported. Reported she had so many medical issues. No further details provided. Prior Vaccinations within 4 weeks were none. Patient previously received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, solution for injection, Batch/Lot Number: EL9899, Expiry Date: Unknown) via Intramuscular route of administration, administered in arm right on 23Dec2021 (at the age of 64-year-old) at dose 1, single for covid-19 immunisation. On an unspecified date in Jan2021 the patient experienced gained 10 pounds, on 04Jan2021 alk phos raised, ast increased, alt increased, on 13Jan2021 fatigue, on 04Feb2021 her liver was diffusely echogenic and fatty, hepatic steatosis. For Alk phos raised, AST increased, ALT increased duration was 15 days. Reported her liver specialist told her that her liver enzymes increased after each Pfizer COVID-19 Vaccine shot she received. She said her liver specialist told her she should report her liver enzymes increasing to Pfizer. Reported she received her first COVID-19 Vaccine on 23Dec2020, providing Pfizer Lot Number: EL9899. She said she received her second COVID-19 Vaccine on 13Jan2021 (between 9:00AM-9:30AM), providing Pfizer Lot Number: EL0142. She said she received both COVID-19 Vaccine doses in her right arm. Reported her last blood work performed before she received her first COVID-19 Vaccine was in Oct2020. She said her Alkaline Phosphatase, ALT, and AST levels had all increased since her last blood work in Oct2020. She said in Oct2020 her Alkaline Phosphatase was 130. She said her Alkaline Phosphatase increased on 04Jan2021 to 163, and then increased, again, on 19Jan2021 to 171. She said her ALT was 29 in Oct2020, and increased on 04Jan2021 to 123, and then increased, again, on 19Jan2021 to 198. She said her AST was 23 in Oct2020, and increased on 04Jan2021 to 75, and then increased, again, on 19Jan2021 to 124. Reported tomorrow she has blood work scheduled to check her immunity and her liver. She clarified her primary care doctor was the one who notified her that her liver enzymes were elevated. She said her primary care doctor sent her to the liver specialist. She said she had her first appointment with the liver specialist 2 weeks ago. She said her liver specialist ordered a variety of blood tests for her liver tomorrow (04Mar2021). Reported she had a liver scan done on 04Feb2021. She said the liver scan report said her liver was diffusely echogenic and fatty. She said there were no discreet lesions. She said the scan read that her pancreas was partially obscured, and there was a cholecystectomy with a normal bile duct. She said the liver scan report said she had hepatic steatosis. Reported after her second COVID-19 Vaccine she had the normal things happen for 24 hours, and fatigue. She said she had continued to have the fatigue for 2 months. She said she had gained 10 pounds since her second COVID-19 Vaccine. Treatment: Declined any. Reported her primary care doctor just sent her to the liver specialist on 04Feb2021, and now the liver specialist had scheduled blood work. Reporter asked if anyone else had reported elevated liver enzymes after receiving the COVID-19 Vaccine. Reporter was advised she would be transferred to Pfizer Medical Information for further assistance. Reporter stated she would call Pfizer Medical Information later on because she wanted to get outside. Adverse Event (AE) Details: Reported her liver specialist told her that her liver enzymes increased after each Pfizer COVID-19 Vaccine shot she received. She said her last blood work performed before she received her first COVID-19 Vaccine was in Oct2020. She said her Alkaline Phosphatase, ALT, and AST levels had all increased since her last blood work in Oct2020. She said in Oct2020 her Alkaline Phosphatase was 130. She said her Alkaline Phosphatase increased on 04Jan2021 to 163, and then increased, again, on 19Jan2021 to 171. She said her ALT was 29 in Oct2020, and increased on 04Jan2021 to 123, and then increased, again, on 19Jan2021 to 198. She said her AST was 23 in Oct2020, and increased on 04Jan2021 to 75, and then increased, again, on 19Jan2021 to 124. She said she had a liver scan done on 04Feb2021. She said the liver scan report said her liver was diffusely echogenic and fatty. She said there were no discreet lesions. She said the scan read that her pancreas was partially obscured, and there was a cholecystectomy with a normal bile duct. She said the liver scan report said she had hepatic steatosis. The adverse events led to physician office (Stated she went to a liver specialist on 04Feb2021). Outcome of the events gained 10 pounds was not resolved, her liver was diffusely echogenic and fatty, hepatic steatosis was unknown, Fatigue was resolving, Alk phos raised, AST increased, ALT increased was resolved on 19Jan2021.  No follow-up attempts are possible. No further information is expected.