This spontaneous case was reported by a consumer and describes the occurrence of COVID-19 (COVID test was positive/got very sick, developed fever, muscle aches, chills, fatigue, loss of taste and smell, and sleeping constantly), DRUG INEFFECTIVE (lack of efficacy), PAIN (little bit of pain), SWELLING (swelling) and MYALGIA (Muscle aches) in a 44-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. Concurrent medical conditions included Asthma.On 23-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form.On 25-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Aug-2021, the patient experienced COVID-19 (COVID test was positive/got very sick, developed fever, muscle aches, chills, fatigue, loss of taste and smell, and sleeping constantly) and DRUG INEFFECTIVE (lack of efficacy). On an unknown date, the patient experienced PAIN (little bit of pain), SWELLING (swelling) and MYALGIA (Muscle aches). At the time of the report, COVID-19 (COVID test was positive/got very sick, developed fever, muscle aches, chills, fatigue, loss of taste and smell, and sleeping constantly) was resolving and DRUG INEFFECTIVE (lack of efficacy), PAIN (little bit of pain), SWELLING (swelling) and MYALGIA (Muscle aches) outcome was unknown.    DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available):On 12-Sep-2021, SARS-CoV-2 test: positive (Positive) COVID test was positive.In September 2021, SARS-CoV-2 test: positive (Positive) two weeks later, COVID test was still positive.On 20-Oct-2021, SARS-CoV-2 test: negative (Negative) nasal swab COVID test was negative.In November 2021, SARS-CoV-2 test: negative (Negative) COVID test was negative, measured via rapid test from laboratories.No concomitant medications were reported. No treatment medications were reported. The patient had been very careful, works at home, and wearing masks. The patient went on a camping trip with one friend to the local mountains at an empty campground. The patient was being followed by a companion nurse and receives calls to check in. The patient seemed to be recovering but was still very fatigued.This case concerns a 44-year-old, male patient, with medical history of asthma, who experienced the serious, unexpected events of Covid-19 (AESI)  and Drug ineffective. The events occurred  6 months after second dose of mRNA 1273 vaccine. The patient went camping with a friend and then he developed fever, muscle aches, chills, fatigue, loss of taste and smell, and sleeping constantly, he recovered but is still feeling after effects of the infection. The rechallenge is not applicable as events have not yet resolved. The patient's history of asthma may have increased his risk of getting infected with Covid-19. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.The patient was still feeling the after effects of the COVID-19 infection.The patient had been positive with COVID until 20-Oct-2021.The patient bought a rapid test on 07-Nov-2021, and then tested negative that was the second negative COVID test.This case was linked to MOD-2021-396294 (Patient Link). Sender's Comments: This case concerns a 44-year-old, male patient, with medical history of asthma, who experienced the serious, unexpected events of Covid-19  and Drug ineffective. The events occurred  6 months after second dose of mRNA 1273 vaccine. The patient went camping with a friend and then he developed fever, muscle aches, chills, fatigue, loss of taste and smell, and sleeping constantly, he recovered but is still feeling after effects of the infection. The rechallenge is not applicable as events have not yet resolved. The patient's history of asthma may have increased his risk of getting infected with Covid-19. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.