The peripheral neuropathy came back very strong in my hands and feet; Nerve pain; I have very bad neuropathy that has returned; I just noticed that it came back after I had my Pfizer shot; peripheral neuropathy came back very strong; having electrical shocks in my head, it was horrible, I said Oh! my gosh, I think, I having an stroke; my LFTs were high; they found a cyst on it /upper GI; nerve damage; having electrical shocks in my head; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 65 year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE), administered in arm left, administration date 01Oct2021 (Batch/Lot number: unknown) at the age of 65 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "High Blood Pressure" (unspecified if ongoing); "chemotherapy" (unspecified if ongoing), notes: successful; "cancer/colon cancer" (not ongoing), notes: cancer survivor; "for heart" (unspecified if ongoing); "peripheral neuropathy" (unspecified if ongoing). Concomitant medication(s) included: LOSARTAN taken for hypertension; AMLODIPINE BESYLATE taken for cardiac disorder. Vaccination history included: Bnt162b2 (Dose 1, Start time: 12:30 , Anatomical Site: left arm), administration date: 10Sep2021, when the patient was 65 years old, for COVID-19 immunization. The following information was reported: NEUROPATHY PERIPHERAL (medically significant) with onset 2021, outcome "unknown", described as "The peripheral neuropathy came back very strong in my hands and feet; Nerve pain; I have very bad neuropathy that has returned; I just noticed that it came back after I had my Pfizer shot"; DISEASE RECURRENCE (medically significant) with onset 2021, outcome "unknown", described as "peripheral neuropathy came back very strong"; CEREBROVASCULAR ACCIDENT (medically significant) with onset 2021, outcome "unknown", described as "having electrical shocks in my head, it was horrible, I said Oh! my gosh, I think, I having an stroke"; LIVER FUNCTION TEST INCREASED (non-serious) with onset 2021, outcome "unknown", described as "my LFTs were high"; CYST (non-serious) with onset 2021, outcome "unknown", described as "they found a cyst on it /upper GI"; NERVE INJURY (non-serious) with onset 2021, outcome "unknown", described as "nerve damage"; ELECTRIC SHOCK SENSATION (non-serious) with onset 2021, outcome "unknown", described as "having electrical shocks in my head". The events "the peripheral neuropathy came back very strong in my hands and feet; nerve pain; i have very bad neuropathy that has returned; i just noticed that it came back after i had my Pfizer shot", "peripheral neuropathy came back very strong", "having electrical shocks in my head, it was horrible, i said oh! my gosh, i think, i having an stroke" and "nerve damage" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: colonoscopy: unknown results; computerised tomogram: found a cyst on it; liver function test: high; ultrasound liver: unknown results. Therapeutic measures were taken as a result of neuropathy peripheral, disease recurrence, nerve injury. Clinical course information: Oncologist recommended the patient to take the COVID vaccine. She waited only two weeks but she "have few of the neuropathy drain to drain the chemotherapy in a way but now I have nerve damage." After she took her Pfizer shot the peripheral neuropathy came back very strong in her hands and feet, described as tingling, nerve pain in hand and in toes. She doesn't know if it was the Pfizer shot, she had no other reactions. The oncologist said they didn't know why the neuropathy had returned. Patient stated that the neuropathy disappeared and went away during the chemotherapy so patient was surprised that it would come back after the second shot. The local doctor said it (peripheral nerve pain) was due to old age. Patient stated she thinks it is the chemotherapy medicine (unspecified product) that is coming back to haunt her.  The lot number for bnt162b2 was not provided and will be requested during follow up.