neuropathy; mild temporary loss of facial muscle movements; profound brain fog; memory loss; impossible to focus; severe fatigue; weight loss; too easily disoriented; distracted; striking pain; electrical shock; heart palpitations; chest discomfort; chest pressure; cannot get a deep breath in; tinnitus; lack of balance; irregular heartbeat; dizziness; weak motor skills; numbness; weakness in arms and legs; abnormal headaches; tingling sensations; extremely cold; muscle spasms; eventually lost too much functionality to perform my job duties; had to resign from my job; depression; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 40-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 02Feb2021 at 12:00 as dose 1, single (Lot number: EL9264) at the age of 40 years, in left arm for covid-19 immunisation. The patient's relevant medical history was not reported. Concomitant medication(s) included: ADVIL [IBUPROFEN]. It has been two years since the patient had the vaccine and most adverse symptoms remain including profound brain fog, memory loss, almost impossible to focus on anything no matter how important the task, severe fatigue no matter how much resting takes place, weight loss, too easily disoriented and distracted, random striking pain resembling electrical shock, heart palpitations with chest discomfort and pressure, cannot get a deep breath in, tinnitus, lack of balance, irregular heartbeat, dizziness, balance, irregular heartbeat, dizziness, weak motor skills and numbness, weakness in arms and legs, neuropathy, abnormal headaches (for me) and tingling sensations that feel extremely cold, muscle spasms, mild temporary loss of facial muscle movements. Symptoms persist and the patient eventually lost too much functionality to perform my job duties and had to resign from her job as a social worker 14 months after Pfizer jab. She feels she will never be the same, and she is still currently not able to return to work resulting in financial chaos, depression. The events "neuropathy", "mild temporary loss of facial muscle movements", "profound brain fog", "memory loss", "impossible to focus", "severe fatigue", "weight loss", "too easily disoriented", "distracted", "striking pain", "electrical shock", "heart palpitations", "chest discomfort", "chest pressure", "cannot get a deep breath in", "tinnitus", "lack of balance", "irregular heartbeat", "dizziness", "weak motor skills", "numbness", "weakness in arms and legs", "abnormal headaches", "tingling sensations", "extremely cold", "muscle spasms", "eventually lost too much functionality to perform my job duties", "had to resign from my job" and "depression" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Heart rate: irregular; Weight: Loss. Therapeutic measures were not taken as a result of neuropathy peripheral, facial paralysis, brain fog, amnesia, disturbance in attention, fatigue, weight decreased, disorientation, distractibility, pain, electric shock sensation, palpitations, chest discomfort, chest discomfort, dyspnoea, tinnitus, balance disorder, heart rate irregular, dizziness, psychomotor skills impaired, hypoaesthesia, muscular weakness, headache, paraesthesia, feeling cold, muscle spasms, loss of personal independence in daily activities, job dissatisfaction, depression.