Fever; Horrible body ache; Excruciating headache; no appetite; have been exhausted; Hives; I had a horrible time/ does not feel normal; I was nauseous; I am just not feeling great; I have no energy; I throw up a few times; My sinus is literally killing me; I have been so sick; This is a spontaneous report received from a contactable reporter (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 59-year-old female patient received bnt162b2 omi xbb.1.5 (COMIRNATY (2023-2024 FORMULA)), on 30Sep2023 at 11:20 as dose 6 (booster), 0.3 ml single (Lot number: HG4628, Expiration Date: Nov2023) at the age of 59 years, in left deltoid for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: Comirnaty bivalent (DOSE 5, Lot#: GJ3274; Expiry Date: May2023), for COVID-19 Immunization; Bnt162b2 (DOSE 4, Lot#: FN2908; Expiry Date: Sep2022), for COVID-19 Immunization; Moderna (DOSE 3), for COVID-19 Immunization; Moderna (DOSE 2), for COVID-19 Immunization; Moderna (DOSE 1), for COVID-19 Immunization. The following information was reported: URTICARIA (non-serious) with onset 30Sep2023, outcome "unknown", described as "Hives"; MALAISE (non-serious) with onset 30Sep2023, outcome "unknown", described as "I am just not feeling great"; FEELING ABNORMAL (non-serious) with onset 30Sep2023, outcome "unknown", described as "I had a horrible time/ does not feel normal"; ILLNESS (non-serious) with onset 30Sep2023, outcome "unknown", described as "I have been so sick"; ASTHENIA (non-serious) with onset 30Sep2023, outcome "unknown", described as "I have no energy"; VOMITING (non-serious) with onset 30Sep2023, outcome "recovered" (Oct2023), described as "I throw up a few times"; NAUSEA (non-serious) with onset 30Sep2023, outcome "unknown", described as "I was nauseous"; SINUS DISORDER (non-serious) with onset 30Sep2023, outcome "unknown", described as "My sinus is literally killing me"; FATIGUE (non-serious) with onset 30Sep2023, outcome "unknown", described as "have been exhausted"; DECREASED APPETITE (non-serious) with onset 30Sep2023, outcome "unknown", described as "no appetite"; HEADACHE (non-serious) with onset 30Sep2023 at 15:00, outcome "not recovered", described as "Excruciating headache"; PAIN (non-serious) with onset 30Sep2023 at 18:00, outcome "unknown", described as "Horrible body ache"; PYREXIA (non-serious) with onset 30Sep2023 at 20:00, outcome "recovering", described as "Fever".  Therapeutic measures were taken as a result of pyrexia.  Additional information: The patient reported that she had a horrible time. Her first two vaccines (Later consumer provided details of 3 Moderna Vaccines and it was not clarified further over the call), she took Moderna (Unspecified Vaccine) and did have the rough time with those. She had the flu for two days, then switched to Pfizer and the last two Pfizer vaccines she had were completely fine, like hardly anything and then she took this one (Comirnaty) on Saturday and she has been so sick and felt she was such 'evicted' to vaccines. She was still just a little worried about herself. She had 102.5 fever, she threw up a few times, horrible body ache, "my sinus is literally killing me", excruciating headache and no appetite and she has been exhausted and then today she woke up with hives. The question was if there is any chance or what she was allergic to it, is there a bad Lot# and if that was normal because she does not feel normal. She added that she was nauseous and throwing out from it and she had hives. Date of adverse event: 30Sep2023. The patient also stated, "I am just not feeling great. Some has improved but some are new like today the hive, I have the hive that is new today. I still have a headache and my fever has been improved it now like about 100, it was 102.5 and I am not throwing up now. I have no energy and no appetite and my sinuses are killing me but they do better when I am up right. So, it is literally everything under the sun like I feel I have experienced, like everything. I took a COVID test make sure that I do not have Covid and I do not have Covid. And the symptoms started, I took that around 11 and then at 3 o'clock I started getting a headache, 6 o'clock I started getting a body ache and then 8 o'clock I have the terrible fever." As for treatment, the patient stated, "I tried not to because right now you are not supposed to, I know I supposed to just let it be. So, I did not until about 24 hours later then I took Tylenol 325 mg and then I took one medication and then I have taken two other one of those now since I took one this morning same mg, Tylenol 325 mg."