Information has been received from a physician concerning a 6 year old female with erythromycin ethylsuccinate (+) sulfisoxazole acetyl allergy and reactive airway disease (RAD) who on 28-JUL-1993 and 21-JUL-1997 was vaccinated with the first and second doses of MMR II, respectively. Secondary suspect therapy included hepatitis B vaccine (manufacturer unknown) vaccinated on 21-MAY-1997, 11-JUL-1997 and 11-AUG-1998, respectively. Concomitant therapy included SUDAFED and CLARITIN. On 14-OCT-1998 the patient was seen by her doctor with complaint of cough, nasal congestion, laryngitis, running nose for 1 week. Her RAD got worse and she using albuterol every 4 hours for 5 days. The physician's assessment was viral illness and RAD exacerbation. Treatments included albuterol as needed and PRELONE 15 mg for 5 days. She would get flu shot soon. On 03-JUN-1999 the patient was seen for low grade temperature to 101 sinus tachycardia. On 15-Sep-1999 the patient presented with cough for 2 weeks, stuffy for 1 week and some sinus tachycardia. Patient had RAD and had been using albuterol. Physical examination showed no abnormality. The physician's assessment was upper respiratory infection (URI) and allergies. Treatment plan included decongestant and continuing albuterol. On 04-DEC-1999 the patient presented with one red, painful lump on right thigh for 2 days and a small pustule on left eyebrow for 1 day. Physical examination showed left eyebrow with 2 mm pustule, right thigh with 2 cm area of erythema with central pustule, tender to touch. Large amount of purulent fluid expressed from the center. The physician's assessment was small abscess on right thigh and tiny pustule in left eyebrow. KEFLEX 500 mg three times a day for 10 days was prescribed. On 27-JUL-2000 the patient was seen by her doctor for pain. She had learning disability-reading. Physical examination showed 20/40 vision of right eye and 20/20 vision of left eye. The physician's assessment was vision defect. She was referred to ophthalmologist. On 15-AUG-2000 the patient was seen with complaint of right ear pain for several days, some cold symptoms and slightly dizzy. She had no pain with touching ear. Physical examination showed no abnormality. The physician's assessment was otalgia, 2 degree eustachian tube dysfunction. Treatment plan included blow nose and decongestant. On 12-OCT-2000 she was seen by her doctor with complaint of spots on the face which started on "Monday" (09-OCT-2000). It was spreading while she was seen. It itched a little and was getting bigger. There was pustule in center. Physical examination showed several erythematous lesions in skin with crust on nose, chin and cheek. One lesion was near right eye with central pustule surrounding erythema. The physician's assessment was impetigo and possible small pustule/abscess near right eye. KEFLEX 500 mg three times a day for 10 days was prescribed. On 23-OCT-2000 the patient had a follow up visit for spots. Patient was still with large lesion near right eye. It was reported that her sister had one lesion like it. Physical examination showed right cheek with white lesion surrounding erythema. There was no drainage expressed. The assessment was abscess/pustule and pilomatricoma. The patient would continue KEFLEX and was referred to dermatologist evaluation. On 29-NOV-2000 she was seen with complaint of cough for more than one week. The sounds were wheezy. She also had dyslexia. Physical examination showed mild wheeze. The assessment was asthma. The treatments included PRELONE 30 mg once a day for 5 days and albuterol inspired every 4-6 hours as needed. On 31-JAN-2001 the patient presented with 3 week cough and less sleep. Physical examination showed wheezy bilaterally (left > right). These assessment was RAD exacerbation. The patient was treated with PRELONE 30 mg once a day for 5 days and albuterol 0.5 ml in 2 cc every 3-4 hours and FLOVENT twice a day. On 15-FEB-2001 the patient was seen by her doctor for spots on the face. KEFLEX was prescribed. On 09-JUN-2001 the patient was seen by a doctor for staphylococcus infection on nose. She was using KEFLEX. Physical examination showed small pustule tip of nose, tender. AUGMENTIN 400 mg twice a day for 7 days was prescribed. On 21-JUN-2001 the patient dropped candle holder on her head and was seen by her doctor. Per her older sister, she had loss of consciousness (LOC) for about 10 seconds. She felt dizzy and nausea. At the time she was seen by the doctor, she was feeling fine. Physical examination showed she was alert with a small bump on her head. The physician's assessment was head injury with possible LOC. There was no evidence of intracranial injury. Patient was sent for neurology evaluation. If symptoms worsened, go to emergency department for evaluation and possible computed axial tomography (CT). Learning disability-reading was considered to be disabling by the reporter. The patient subsequently developed adverse events after vaccinated with hepatitis A virus vaccine inactivated (WAES#0909USA00550) and adverse events after vaccination with GARDASIL (WAES #0908USA03159). Additional information is not expected. All available medical records will be provided upon request.