This spontaneous report was received from a nurse practitioner, via a company representative, concerning a patient of unknown age and gender. The patient's pertinent medical history, concurrent conditions and concomitant medications were not reported. On an unspecified date, the patient received the first dose of GARDASIL 9. On 09-MAR-2019, the patient received the second dose of GARDASIL 9 for prophylaxis (strength, dose, frequency, route of administration, lot number and expiration date were not reported). On 11-MAR-2019, 2 days after receiving vaccination with GARDASIL 9, the patient experienced sore throat, headache, swollen glands, achiness and fever. On the same date, the patient was seen in an unspecified clinic and she was checked for flu and stretptococcus (reported as "strep"). At the time of reporting, the outcome of sore throat, headache, swollen glands, achiness and fever was unknown. The causal relationship between the vaccination with GARDASIL 9 and the events was not provided by the reporter. This is a non-valid case due to lack of patient's identification. Upon receipt of follow-up, it was determined that the case is now valid. Follow up information has been received from a registered medical assistant on 26-MAR-2019. This female patient was 24 years old (currently 25 years old). There were none other vacations within 4 weeks prior. Concomitant therapy included acetaminophen. The patient was otherwise healthy, stated she went get sick frequently so she took beta-glucan supplement daily for immune support. She denied hypertension, diabetes, heart disease. There was no known allergies and none surgical history. The patient had family history of father's hypertension. The patient was an alcohols user and a never smoker. On 06-JAN-2019, the patient received the first dose of GARDASIL 9. The dose of the second dose was 0.5 ml and the lot# was N028092 and the route was intramuscular in the left arm. On 11-MAR-2019, the patient also experienced nausea, swollen gland in throat (previous reported as swollen gland), low grade fever (previous reported as fever) and sore injection site. (It was reported that the patient started looking nauseous in the afternoon and the patient went home due to headache and sore throat/swollen gland shortly after the nausea. Patient went to urgicare with compliant of sore throat fatigue, body aches and tested negative for flu or strep. Patient stayed home and 12-MAR-2019 from work. Patient felt better by 15-MAR-2019. Symptom completely gone). The results of review of systems were: Constitutional: positive for fatigue. negative for chills and fever. Hent: positive for sore throat. negative for congestion and sinus pain. Eyes: negative for pain and redness. Respiratory: negative for cough, chest tightness, shortness of breath and wheezing. Cardiovascular: negative for chest pain. Gastrointestinal: negative for abdominal pain, constipation, diarrhea, nausea and vomiting. Musculoskeletal: negative for arthralgias and joint swelling. Skin: negative for rash and wound. Neurological: negative for headaches. Psychiatric/Behavioral: negative for agitation. the patient was not nervous/anxious. The result of physical exam on 12-MAR-2019 was blood pressure 113/71, pulse 87, respiratory rate 18, temperature ((TempSrc: oral) 98 Fahrenheit (36.7) degree Celsius, blood oxygen saturation 100%. The outcome of events was recovered. There was no prescription drug treatment for the experience required.