Someone I know (adult) got Cushing's Syndrome after getting the Pfizer 19 vaccine.; Her mind doesn't work anymore; belly and face swollen; belly and face swollen; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 66-year-old female patient received BNT162b2 (BNT162B2), as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "Carpal tunnel syndrome" (unspecified if ongoing), notes: Carpal tunnel syndrome; "Kidney stone" (unspecified if ongoing), notes: Kidney stone; "Cesarean section" (unspecified if ongoing), notes: Cesarean section Has had two C-sections. Concomitant medication(s) included: FLONASE [FLUTICASONE PROPIONATE] taken for hypersensitivity. Vaccination history included: BNT162b2 (Dose 1, LOT: EN6205, Anatomical location: Left arm), administration date: 27Feb2021, when the patient was 66-year-old, for COVID-19 Immunization; BNT162b2 (Dose 2, LOT: EN6204   , shot in the left arm), administration date: 20Mar2021, when the patient was 66-year-old, for COVID-19 Immunization. The following information was reported: CUSHING'S SYNDROME (hospitalization, medically significant), outcome "unknown", described as "Someone I know (adult) got Cushing's Syndrome after getting the Pfizer 19 vaccine."; THINKING ABNORMAL (non-serious), outcome "unknown", described as "Her mind doesn't work anymore"; SWELLING FACE (non-serious), ABDOMINAL DISTENSION (non-serious), outcome "unknown" and all described as "belly and face swollen". The events "someone i know (adult) got cushing's syndrome after getting the pfizer 19 vaccine.", "her mind doesn't work anymore" and "belly and face swollen" required physician office visit. The patient underwent the following laboratory tests and procedures: Blood glucose: (20May2021) over 500, notes: When she went to the hospital; Body height: (unspecified date) shrunk; adrenals: (20May2021) 2000, notes: her adrenals were supposed to be 40; Magnetic resonance imaging: (unspecified date) Cant find a tumor; Positron emission tomogram: (unspecified date) Cant find a tumor.  Clinical information: Someone patient knew (adult) got Cushing's Syndrome after getting the Pfizer 19 vaccine. She thinks the patient got the 1st and 2nd doses, maybe the 3rd. She does not know what formulation the patient received. Flonase used a lot for allergies, but not everyday. Patient had the vaccine in Feb2021 and the second one in Mar2021. Wound up with cuhsing's. Read that the vaccine could cause adrenal crisis. Met someone else who got the vaccine around the same time, just a couple weeks apart, and they both have crushing's. She has never been sick a day in her life. Not a big believer in the vaccines anyway. Has been sick now for a year. The other person got Cushing's and so did she.  She was in the hospital for 8 weeks. The other guy she knows who got Cushing's is going to report it online. She has never even had the common cold. She is 67 and never had anything. Maybe, a kidney stone one time.Two hospitals couldn't diagnose her. Her cousin diagnosed her. The Cushing's created diabetes, but that's under control right now. She is on strong medicines for the cushing's.  Her mind doesn't work anymore. The Cushing's makes her belly and face swollen. Her face has gone down. But the other guy she knows who got it, he looks worse than her. Her height also shrunked. The two of them both got Cushings and its so rare, and they both got the vaccine around the same time. She cant work. Its ruined her life. She misses going out and working. She babysits 5 days a week for her daughter, but it takes everything out of here. Cushing's affects her bones and everything. The adrenal gland affects everything. Going to her PCP today, because the bottom of her legs are turning red and she doesn't know why. She sees a primary doctor, a Cushing's doctor, and diabetes doctor. Hasn't mentioned this idea about the Covid-19 vaccine to her Cushing's doctor yet. The other guy with Cushing's, he goes to the same Cushing's doctor. In May2021, she passed out, her face was swollen, her belly and ankles were swollen. On 20May2021, her son took her to hospital and her adrenals were supposed to be 40 and were 2000. If her cousin hadn't diagnosed her, she would've been dead in two weeks. Diagnosed with her diabetes at first. She was crazy. She was either cursing or was really nice. Was in IC for about a week. came home and wound up back in the local hospital. Local hospital never diagnosed her with diabetes. She was discharged home and she went crazy. Her husband was afraid of her. She was cursing. Her husband called her cousin and she came over and the cousin said, she has Cushing's take her to the hospital. So, her husband took her back to shore memorial. She may or may have not stayed there. She can't remember. She went in an ambulance to (withheld) hospital and stayed there for 5-6 weeks. Were treating the diabetes and the crushing's. They were looking for a tumor to explain the cushing's. Did MRIs and pet scans. Cant find a tumor. With (withheld), they found a tumor and took it out, but he's not better. At least she is functioning a little bit. She doesn't do a lot. Used to cook and clean and work. All that was just a year and a half ago. She cries all the time and her doctor thinks she's crazy.  She doesn't need antidepressant. Put her on an antidepressant once and she almost committed suicide. Only cries when she talks to people. Doesn't get any vaccines. Only did this for her grandkids. Doesn't get flu shots or anything. People were dying and she was scared. It's so weird that both her and (name) would get Cushing's and its online that it could cause adrenal crisis. She didn't even know what an adrenal gland was. She's on strong medicines and she hates taking medicines. She was blaming a nose spray she used to take once in a while. and then she found out that (name) got Cushing's after the vaccine too. When she went to the hospital, her glucose was over 500. She doesn't remember anything for the first 4 weeks. Now, the glucose is good. She's not taking medicine for the diabetes now because the adrenal glands are under control, so the diabetes in under control. Goes to the Cushing's doctor in Jan2023.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201318515 similar report from the same reporter;