chest pain; shortness of breathe; having difficulty standing; Thought she was having a heart attack; O2 saturation decreased; Another lab (she could not identify) that was high; This is a spontaneous report from a contactable consumer (patient). A 48-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Right on 01May2021 (Lot Number: EW0175) as 2ND DOSE, SINGLE DOSE for covid-19 immunisation. Patient took the first dose in Arm Right on 10Apr2021 (Lot Number: ER8730) for covid-19 immunization, and experienced hand pain, skin tightness, difficulty in standing, pain, heaviness in arm, back pain, walking difficulty. Vaccine Administered at (Name) Facility was No. Medical history included, sickle cell from 01Sep1972 and ongoing, ongoing penicillin allergy since she was a kid, ongoing drug allergy to other medications. The patient's concomitant medications were not reported. Patient stated she got the second shot on 01May2021 and she did not experience the funny feeling and had nothing at the injection site. Sunday was okay. Monday morning around 7am she started having severe chest pain and shortness of breathe and couldn't breathe. It was getting more and more severe. She had an appointment and the Nurse Practitioner said next time don't stay home and go to an ER if you feel all that pain. So on Tuesday she said let me get out of the house and go to the appointment. Someone that understood saw her and thought she didn't look well and ambulance people said she did not look well and they wanted her to go to the ER. She said she would watch it because she had a similar reaction with the first one but it was in her back. They checked her out and said it is the vaccine because she was not having this severity of anything before and they wanted to take her to the ER. They took her information and she said let me watch it and see. She continued to her appointment and it got worse and worse and in the evening after the appointment they had to take her to the ER because she thought she was having a heart attack. At the ER they drew troponin, which was normal, and another lab (she could not identify) that was high and they thought she may have had a blood clot so they did a CT with contrast and it was negative for blood cot, so they ruled out a blood clots in her lungs. Patient reported that while she was out for her errands and appointments, someone was concerned for her on the street because she was very short of breath and having difficulty standing. Patient reported that there was a fire department ambulance parked close by. It reported that the paramedics assisted her into the ambulance and took her pulse ox and blood pressure. The paramedics told her that her O2 sat was low and wanted her to go to the hospital via ambulance. Caller reported that she did not want to have to pay the bill for the ambulance, so she declined transport to the emergency room. Caller reported that she want to another appointment. Caller reported that the pain was there and was severe, but she pushed through with the thought in the back of her head that the chest pain would not continue. Caller reported that she kept hanging on to the thought that maybe the chest pain will last the same amount as her back following the first dose of the Covid-19 vaccine. Caller reported that around 4:00 PM or 5:00 PM on 03May2021, the chest pain was not going away and she was concerned for her heart. Caller reported that she was taken over to the emergency room. Caller reported that while she was in the emergency room, she was trying to tell the staff that she had gotten the Covid-19 vaccine. Caller reported that the emergency room staff was more concerned about doing things and wanted to give her aspirin. Caller reported that she refused the aspirin and told the emergency room staff to do lab tests first. Caller reported that her troponin came back and the emergency room staff said that her heart was ok at that time. Caller reported that she was still short of breath and her O2 sat was very low while she was in the emergency room on 03May2021. Caller reported that another lab test was very high. Caller reported that she was not kept overnight in the emergency room. Caller reported that she came home after leaving the emergency room and the chest pain was there during the night on 03May2021. Caller reported that on 04May2021 around midday, the chest pain started subsiding but she was still sore breathing in and out. Caller reported that by Thursday, 06May2021, there was just soreness in her chest and by Friday, 06May2021, she was fine and back to baseline. Caller reported that the emergency room physician informed her that her side effects may be something to do with the Covid-19 vaccine. Caller reported that it has to be the Covid-19 vaccine that caused her side effects. Event chest pain required a visit to Emergency Room, no event required a visit to Physician Office. The outcome of events were reported as recovered on 07May2021.