Vaccination failure; COVID-19 positive test  in between the second dose and booster dose; This spontaneous case was reported by an other health care professional and describes the occurrence of COVID-19 (COVID-19 positive test  in between the second dose and booster dose) and VACCINATION FAILURE (Vaccination failure) in a 20-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 047B21A and 003B21A) for COVID-19 vaccination.     Concurrent medical conditions included Childhood asthma and Schizophrenia.   On 22-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 15-Jan-2022, the patient experienced COVID-19 (COVID-19 positive test  in between the second dose and booster dose). On an unknown date, the patient experienced VACCINATION FAILURE (Vaccination failure). At the time of the report, COVID-19 (COVID-19 positive test  in between the second dose and booster dose) and VACCINATION FAILURE (Vaccination failure) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 15-Jan-2022, SARS-CoV-2 test: (Positive) Positive.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant drug reported. No treatment information was provided by the reporter.  Company Comment: This spontaneous case concerns a 20-year-old male patient with no relevant medical history reported, who experienced the unexpected non-serious AESI of COVID-19 which occurred approximately 9 months after receiving the second dose of mRNA-1273 vaccine in covid-19 vaccination series. Additionally, vaccination failure is noted in the case, as it satisfies the criteria of LOE (LOE noticed more than 15 days (approximately 9 months) after the second dose and the interval between the two doses is around 29 days with Moderna vaccine). No further details on clinical course, other lab test results and treatment received were reported. The outcome of events was reported as unknown. The current pandemic situation of COVID-19 may remain as confounder to the event Covid-19. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-600689 (Patient Link).; Sender's Comments: This spontaneous case concerns a 20-year-old male patient with no relevant medical history reported, who experienced the unexpected non-serious AESI of COVID-19 which occurred approximately 9 months after receiving the second dose of mRNA-1273 vaccine in covid-19 vaccination series. Additionally, vaccination failure is noted in the case, as it satisfies the criteria of LOE (LOE noticed more than 15 days (approximately 9 months) after the second dose and the interval between the two doses is around 29 days with Moderna vaccine). No further details on clinical course, other lab test results and treatment received were reported. The outcome of events was reported as unknown. The current pandemic situation of COVID-19 may remain as confounder to the event Covid-19. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.