Severe itching knee to neck / itching in clear area with no rash; Big rashes, some are red and some are brown; Leg weakness; Doesn't feel strong / not gain energy at all; can't sleep; rash has a burning feeling; breathing affected a little bit; discomfort around area of her heart; concerned about something going on inside her body; Chills; Heavy nose bleeds/ left nostril nose bleed (multiple episodes) / right nostril nose bleed (multiple episodes); Spongiotic Dermatitis Eosinophilia; Spongiotic Dermatitis Eosinophilia; Itchy rash all over the body; This spontaneous case was reported by a consumer and describes the occurrence of ECZEMA (Spongiotic Dermatitis Eosinophilia), EOSINOPHILIA (Spongiotic Dermatitis Eosinophilia), RASH PRURITIC (Itchy rash all over the body), PRURITUS (Severe itching knee to neck / itching in clear area with no rash) and RASH ERYTHEMATOUS (Big rashes, some are red and some are brown) in an 81-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 013M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.  Concomitant products included ROSUVASTATIN CALCIUM (CRESTOR), ACETYLSALICYLIC ACID (BABY ASPIRIN), ROSUVASTATIN and CETIRIZINE HCL for an unknown indication.    On 06-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 08-Feb-2021, the patient experienced ECZEMA (Spongiotic Dermatitis Eosinophilia), EOSINOPHILIA (Spongiotic Dermatitis Eosinophilia) and RASH PRURITIC (Itchy rash all over the body). In March 2021, the patient experienced EPISTAXIS (Heavy nose bleeds/ left nostril nose bleed (multiple episodes) / right nostril nose bleed (multiple episodes)). On an unknown date, the patient experienced PRURITUS (Severe itching knee to neck / itching in clear area with no rash), RASH ERYTHEMATOUS (Big rashes, some are red and some are brown), MUSCULAR WEAKNESS (Leg weakness), ASTHENIA (Doesn't feel strong / not gain energy at all), INSOMNIA (can't sleep), BURNING SENSATION (rash has a burning feeling), DYSPNOEA (breathing affected a little bit), CARDIAC DISCOMFORT (discomfort around area of her heart), FEELING ABNORMAL (concerned about something going on inside her body) and CHILLS (Chills). The patient was treated with TRIAMCINOLONE ACETONIDE for Rash, at a dose of 1 dosage form. On 08-Jul-2021, EPISTAXIS (Heavy nose bleeds/ left nostril nose bleed (multiple episodes) / right nostril nose bleed (multiple episodes)) had resolved. At the time of the report, ECZEMA (Spongiotic Dermatitis Eosinophilia), EOSINOPHILIA (Spongiotic Dermatitis Eosinophilia), RASH PRURITIC (Itchy rash all over the body), PRURITUS (Severe itching knee to neck / itching in clear area with no rash), RASH ERYTHEMATOUS (Big rashes, some are red and some are brown), MUSCULAR WEAKNESS (Leg weakness) and ASTHENIA (Doesn't feel strong / not gain energy at all) had not resolved and INSOMNIA (can't sleep), BURNING SENSATION (rash has a burning feeling), DYSPNOEA (breathing affected a little bit), CARDIAC DISCOMFORT (discomfort around area of her heart), FEELING ABNORMAL (concerned about something going on inside her body) and CHILLS (Chills) outcome was unknown. Not Provided    DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Biopsy skin: spongiotic dermatitis eosinophilia (Inconclusive) revealed in biopsy.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   She also mentioned that her HCP (who got information from CDC) had told her not to get the second dose of vaccination. Later the patient reported that she had leg weakness and did not feel strong. She had not gained energy at all. The patient had severe itching from knee to neck and the rash was still there described as big rashes, some were red and some were brown. There was Itching in clear area with no rash. Sometime in Mar-2021, the patient had nosebleeds (she never had before).On 16-Apr-2021, 20-Apr-2021, 23-Apr-2021, 28-Apr-2021, and 01-May-2021 she had right nostril nose bleeds. On 15-May-2021, 17-May-2021, 20-May-2021, 24-May-2021 she had heavy bleeding from left nostril.   Most recent FOLLOW-UP information incorporated above includes: On 24-May-2021: Additional information appended on 24-MAY-2021:included vaccine batch #, concomitant products, and additional events. On 14-Jul-2021: Follow-up document appended on24-MAY-2021:Significant follow up appended to AER