fatigue/Extreme exhaustion; fever and flu like symptoms; fever and flu like symptoms; This is a spontaneous report from a contactable other healthcare professional (Nurse) via team. This is 1 of 3 reports. A 67-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot Number: EP7534), dose 2 via an unspecified route of administration, administered in Deltoid Left on 17Mar2021 (around noon) as single dose for covid-19 immunisation. Patient previously received dose 1 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot Number: EN6202), via an unspecified route of administration administered in Deltoid Left on 24Feb2021 11:00 as single dose. Medical history included hypothyroidism diagnosed for about 10 years. it was well controlled. Patient adds that she is healthy and she usually exercises half an hour to an hour every single day and she is very active, so she is normally fine. About 25 years ago, she got the flu shot and she had some redness at the site but that was all. Patient states she can not think of anything. Her kids and son-in-law and sister and friends got the Pfizer Covid-19 Vaccine too and got one day of being tired and achy and then bounced back to normal. The patient's concomitant medications were thyroid medication (Vitamins) no additional details provided. Patient reported that she had both doses of the Pfizer covid 19 vaccine in February and March. She states she is a nurse, too, and she has been trying to figure this out. She got her first vaccine in the end of February and then it was 17Mar2021 that she got her her second vaccine. She had 10 days of fatigue after the first one, and then got over it and it was fine. Patient reported that since the day of the second vaccine she has had extreme fatigue and very very tired. Patient reported that she is slightly better noting that it has changed her lifestyle. Patient wanted to know if other patients have experienced extended fatigue (past a week). Patient asked is there anything she can do about this. Patient asked what physiologically could be causing this. Patient adds that she did have 5 days of fever and flu-like symptoms. Patient did not expect it to be long. she has had daily extreme exhaustion. Patient has never felt this way. She is fit and active and exercise. It has knocked her down. Patient adds that she has been to the doctor a couple of times and they checked it out and it was no anemia or thyroid problems. Patient just wanted to report this. Also, patient wants to know if other people after the vaccine had this for week, 8 weeks of fatigue she is going on. Patient adds that her flu-like and fever went away after the first vaccine and then came back three hours after the second. After the first vaccine, it was the same - it came on in about 3 or 4 hours. Patient adds that she has only exhaustion now and this is medically significant because it changed her life style and she had to say no to a lot of people and not go places. Patient adds it changed quite a bit and that the flu-like symptoms went away 2 days after the 2nd vaccine. Patient states it is not serious because 101 was the highest that it got. It was what she expected, the flu part of it. Patient states that it is going to take a while because she is not zipping upstairs like she is used to. Patient clarifies that she is not zipping upstairs due to the exhaustion, she is just trying to take it easier. Patient did not receive other vaccine in four weeks of vaccination. On an unspecified date, the patient experienced fatigue/extreme exhaustion, fever and flu like symptoms. The event fatigue/extreme exhaustion was reported as medically significant. The patient underwent lab tests and procedures which included blood test: normal, body temperature: 101, fibrin d dimer: normal, full blood count: normal, oxygen saturation: 99, thyroid function test: normal, urine analysis: normal on an unspecified date. Glucose and heart rate was also reported in lab works without results and on unspecified date. She did not have any shortness of breath or cough. Reportedly, the events was related to the vaccine. Outcome of the event fatigue was recovering and fever and flu was recovered.  On 14May2021, Patient provided and spelled her first name. No further information expected. Information about lot/batch number cannot be obtained.; Sender's Comments: Based on the information available and a close temporal association, a possible contributory role of the suspect BNT162B2 cannot be excluded for the reported events of  fatigue,influenza like illness,pyrexia. The case will be reassessed once new information is available. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to agency as appropriate