chest tightness; limbs were hot to touch; skin kept getting tighter and tighter and her limbs blew up more; her right arm will become stiff and there is a little bit of pinching around her bicep area; her right arm will become stiff and there is a little bit of pinching around her bicep area; it was beating a little hard and just a little tight but that could have been excitement from it all; limbs "swelling up and felt like it will explode/She is still getting some swelling in her right arm occasionally; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 54 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 22Apr2021 (Lot number: EW0172) at the age of 53 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "allergic to: latex" (unspecified if ongoing); "allergic to: hamster" (unspecified if ongoing); "allergic to: guinea pig hair" (unspecified if ongoing); "allergic to: red dye" (unspecified if ongoing); "allergic to: penicillin" (unspecified if ongoing); "allergic to: bee stings" (unspecified if ongoing); "allergic to: dyes used in jeans" (unspecified if ongoing); "allergic to: trees" (unspecified if ongoing); "allergic to: pollen" (unspecified if ongoing); "Overweight" (unspecified if ongoing); "inflammation problem" (ongoing), notes: She has had all for more than 10 years.; "acid reflux" (ongoing), notes: She has had all for more than 10 years.; "mild asthma" (ongoing), notes: She has had all for more than 10 years.; "Sleep apnea" (ongoing), notes: She has had all for more than 10 years.; "vestibular migraines with vertigo" (ongoing), notes: She has had all for more than 10 years but she wasn't diagnosed until 5 years ago.; "vestibular migraines with vertigo" (ongoing), notes: She has had all for more than 10 years but she wasn't diagnosed until 5 years ago. She is taking over the counter Pepcid AC and she does use an inhaler sometimes, albuterol, but she doesn't use that every day and she doesn't have to have it. She has like a mild asthma, very mild, but she does have sleep apnea and that might weigh into the factor. Inquired for when these began and she says she has had them all for more than 10 years. She also does have vestibular migraines with vertigo but that shouldn't affect the swelling, she has had that for more than 10 years but she wasn't diagnosed until 5 years ago. Concomitant medication(s) included: ALBUTEROL SULFATE HFA taken for asthma (ongoing); PEPCID AC, start date: 2015 (ongoing). Pepcid AC: If she were to take 2 Pepcid ACs then it would give her vertigo. Albuterol: She has had this for years and years. Sometimes she doesn't even have to use or just use it once a week, it is specifically albuterol sulfate HFA. Past drug history included: Codeine, reaction(s): "Allergies". Vaccination history included: Bnt162b2 (Lot Number: EP7533, Route, Anatomical Location: left arm, Date: 01Apr2021), administration date: 01Apr2021, when the patient was 53 years old, for Covid-19 immunization, reaction(s): "fine and she didn't even have one problem". The following information was reported: CHEST DISCOMFORT (hospitalization), outcome "unknown", described as "chest tightness"; PERIPHERAL SWELLING (hospitalization) with onset 24Apr2021, outcome "not recovered", described as "limbs "swelling up and felt like it will explode/She is still getting some swelling in her right arm occasionally"; FEELING HOT (non-serious), outcome "unknown", described as "limbs were hot to touch"; SKIN TIGHTNESS (non-serious), outcome "unknown", described as "skin kept getting tighter and tighter and her limbs blew up more"; HEART RATE IRREGULAR (non-serious) with onset 28Apr2021, outcome "recovered" (28Apr2021), described as "it was beating a little hard and just a little tight but that could have been excitement from it all"; MUSCULOSKELETAL STIFFNESS (non-serious), PAIN IN EXTREMITY (non-serious), outcome "unknown" and all described as "her right arm will become stiff and there is a little bit of pinching around her bicep area". The events "limbs "swelling up and felt like it will explode/she is still getting some swelling in her right arm occasionally", "skin kept getting tighter and tighter and her limbs blew up more", "it was beating a little hard and just a little tight but that could have been excitement from it all", "her right arm will become stiff and there is a little bit of pinching around her bicep area" and "her right arm will become stiff and there is a little bit of pinching around her bicep area" were evaluated at the physician office visit and emergency room visit. Clinical course: Caller said she have received the 2nd dose of the Pfizer covid vaccine but after her dose, she experienced the following adverse events: limbs "swelling up and felt like it will explode", limbs were hot to touch, chest tightness that lasted for a few hours. Her doctor recommended her to get an allergy test for the covid vaccine but she has some hesitations because the test was expensive. Caller also stated that she was allergic to the following but not limited to: latex, hamster and guinea pig hair, red dye, penicillin, bee stings, dyes used in jeans, codeine, trees, and pollen. Caller really wanted to get the vaccine as booster for her protection but her doctor advised her to not the Pfizer vaccine as she have had an allergic reaction to it from her 2nd dose. She wanted to know if the side effect that she had was reported for the 2nd dose and the booster. Caller says that she can't get her booster shot for COVID because her 1st COVID vaccine went fine that she had on 01Apr2021 but when she had her 2nd COVID vaccine, days later she had to go to the hospital because her limbs just swelled up so much. They had so much pressure that she actually felt like they were going to explode. She waited a couple days before she went to the emergency room because it was the weekend and she thought that she was going to be okay and that it was going to go away but her skin kept getting tighter and tighter and her limbs blew up more. She didn't really feel like her heart was racing but when she did go to hospital that day it was beating a little hard and just a little tight but that could have been excitement from it all. Is there anything that she can do to get the booster or further COVID vaccines? Her doctor doesn't want her to have the booster dose because he says that she should be tested for allergies first but she hears that there is no actual allergy test for the COVID vaccine. Also, she is considerably overweight, she is on the obese side but not extreme. She did read that there are a lot of overweight people that already have inflammatory diseases and she has that from being overweight and from acid reflux so cue that into that. She already has an inflammation problem and she knows that COVID is an inflammatory problem. She had her 2nd dose of the Pfizer COVID vaccine on 22Apr2021. The swelling began two days after she had the vaccine. She noticed that her arms were getting tight and swelling up, confirmed to begin on 24Apr2021. She confirms that when she went to the hospital she stayed in the emergency room area. She asked them if it was blood clots so they checked for blood clots and they said that there were no blood clots. When she told them that she just had the 2nd COVID vaccine they really didn't even do anything else after that. She says the heart sensations were just the day that she went to the hospital and it could have just been from the excitement and so much pressure in all of her limbs. She didn't know if it was blood clots or what it was. She is still getting some swelling in her right arm occasionally. The vaccine was not administered in her right arm, she had her shots in her left arm and it is her right arm that keeps doing it occasionally but it is not anything like it was previously. She was given muscle relaxers to release the pressure she guesses which will take it down some but it took days to take it down. Her arm will be fine for a days or for a week and then all of a sudden her right arm will become stiff and there is a little bit of pinching around her bicep area and on the outer part of her arm, a little bit of swelling. Again, it could be fine for days and then it might happen again The sensations that she felt in her heart were not like her heart was racing it was just like a tightness she guesses. It wasn't like she felt like she was having a heart attack and it just could have been from the excitement of what was happening, she is not sure. She is trying to find the day that she went to the hospital. During the vaccine supplemental form she provided that she went to the hospital on 28Apr2021. She says her chest was only tight for like maybe a couple of hours that day and then it subsided. Her 1st dose was fine and she didn't even have one problem. When she had her 2nd vaccine she was complaining to her sister and her mother that it was given crooked, they are supposed to give the shot straight on, but this was crooked and she was complaining about that. She doesn't know if that can have anything to do with it.  Vaccination Facility Type was Giant grocery store chain. Vaccines Administered on Same Date of the Pfizer Suspect was None. AEs require a visit to: Emergency Room and Physician Office. None Prior Vaccinations (within 4 weeks). AE(s) following prior vaccinations: She never has before. She has gotten a flu shot every single year but this year when she had the flu shot on either 26Aug2021 or 27Aug2021 she started to get a little bit of swelling, a very little bit, and a lot of heat. She also had that with her 2nd COVID vaccine, she had a lot of heat with the swelling, she was hot to touch and her legs were so hot to touch and her arms. She barely got any swelling after the flu shot but it was enough to tell her maybe she won't dare to get it next year and she has never had that before. Inquired for  number and expiry date and she declined to provide because she received this at  and maybe they did give her a lot number but she thinks that because it was free she didn't keep that. Family Medical History Relevant to AE(s): None. When they were checking to see if the problem was blood clots from the vaccine they took some big long thing that she doesn't know the name of and they roll and run it up and down your limbs and push hard to test the veins. They told her that she has very small veins. She was telling her mother, who is 85 years old, that the doctors said that she had small veins and her mother said that the caller's father had the same thing and that they had a hard time testing his veins because his veins were small. Of course since the caller weighs more they had to press more on her to see how her veins were doing and to locate them.  No follow-up attempts are possible. No further information is expected.