I had a headache on/off before getting the vaccine/she had the headache before the second vaccine; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 66 year-old female patient received bnt162b2 (BNT162B2), administered in arm right, administration date 11Mar2021 15:30 (Lot number: EN6207) at the age of 66 years as dose 1, single for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Past drug history included: Penicillin, reaction(s): "lost her blood pressure", notes: States 40 years ago she got a shot of penicillin in her butt and lost her blood pressure. The following information was reported: HEADACHE (non-serious) with onset 27Mar2021, outcome "not recovered", described as "I had a headache on/off before getting the vaccine/she had the headache before the second vaccine". Therapeutic measures were taken as a result of headache.  Additional information: Patient wants to know if the following medications are permitted to be take post vaccination to treat symptoms Tylenol, Ibuprofen and Aspirin. Patient states she was calling about the Pfizer Covid Vaccine. Her second vaccine was yesterday at 3:30p.m. States she woke up in the middle of the night at 03:30a.m. with bad muscle aches, nausea, headache, fever over 101, and chills. States the Tylenol didn't seem to help much. States the Ibuprofen didn't help either. Equate Ibuprofen Expiration: Dec2021 Lot: OCE2790A UPC Unknown and Acetaminophen Expiration: May2022 Lot: P139389 UPC Unknown. Caller states that her teeth, gums, and face hurt as well. States she doesn't know if it is a delayed reaction or if she could've gotten Covid again. States she had the headache before the second vaccine but now it is worse. States she was told that unless she had a fever, she could take the vaccine. States she contacted the doctor and they just said to use a nasal rinse and contact them if she doesn't feel better in 7-10 days. Patient was asked if this is related to the vaccine. PCP: Declines, retired a few months ago and haven't seen a new one, email clinic and hadn't seen anyone; (Institute name) surprised told to wait 7-10 days. Clarifies that her face still hurts but her teeth and gum pain is completely gone. States when she bit it hurt, it was like they hit each other. States she doesn't currently have fever and chills, the medicine brought it down, but she isn't sure if it is completely gone. Treatment was reported as Tylenol and Ibuprofen, Ice and Heat. Suspect product: AE(s) following prior vaccinations was reported as none. They told the first vaccine will be worst, but I only had a few symptoms for a day. It's funny because she had fever the next day with chills and body ache. Is it normal to have all these symptoms after receiving the vaccine. Patient wants to know if it's safe for a COVID positive patient to receive the Pfizer COVID-19 vaccine. Patient wants to know would it be safe to receive the Pfizer COVID-19 vaccine if she was actively COVID positive. Is report related to a study or programme was reported as no. Vaccination facility type was reported as other. Vaccine Administered at Military Facility was reported as no. Additional Vaccines Administered on Same Date of the Pfizer Suspect was none. Other Products reported as no. Investigation Assessment was reported as no. Adverse events was not resulted in emergency room and physician office. Family Medical History Relevant to AE(s) reported as none. Patient calling to report adverse events from the Covid vaccine. States she took Tylenol [really it was acetaminophen] and Ibuprofen and they didn't really help her headache. Equate Ibuprofen expiration was Dec2021, Lot:OCE2790A UPC Unknown and Acetaminophen Expiration: May2022, Lot: P139389, UPC Unknown.   No follow-up attempts are possible. No further information is expected.