it was the booster shot; It''s a weird side effect, it was the white elephant in room; triggering the aggression; increased adrenaline and dopamine; increased adrenaline and dopamine; hurt like hell; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 54 year-old patient received bnt162b2 (BNT162B2), intramuscular, administered in deltoid left, administration date 09Nov2021 (Batch/Lot number: unknown) at the age of 54 years as dose 3 (booster), single for covid-19 immunisation. The patient's relevant medical history was not reported. Concomitant medication(s) included: VITAMIN D [COLECALCIFEROL]. Vaccination history included: Covid-19 vaccine (Dose: 01, MANUFACTURER UNKNOWN), administration date: Feb2021, when the patient was 53 years old, for Covid-19 immunization; Covid-19 vaccine (Dose: 02, MANUFACTURER UNKNOWN), administration date: Mar2021, when the patient was 53 years old, for Covid-19 immunization. The following information was reported: IMMUNISATION (non-serious) with onset 09Nov2021, outcome "unknown", described as "it was the booster shot"; FEELING ABNORMAL (non-serious) with onset Nov2021, outcome "unknown", described as "It''s a weird side effect, it was the white elephant in room"; AGGRESSION (non-serious) with onset Nov2021, outcome "unknown", described as "triggering the aggression"; EPINEPHRINE INCREASED (non-serious), BLOOD CATECHOLAMINES INCREASED (non-serious) all with onset Nov2021, outcome "unknown" and all described as "increased adrenaline and dopamine"; PAIN (non-serious) with onset Nov2021, outcome "unknown", described as "hurt like hell". The patient underwent lab tests and procedures which  included adrenaline and dopamine (Blood catecholamines) and epiphrinine) increased on an unspecified date in 2021, blood test blood work for hormones on an unspecified date Additional Context:  Consumer stated, "the patient want a report a side effect, the vaccine to you guys. The patient had been doing research and it was kind of a white elephant in the room, right? The patient had been noticing including myself that after we get the booster shot, right? It's a weird side effect, right? and this happens it was the white elephant in room. So, the patient started doing research on it and when people get sick they get grumpy you know, obviously their arm sores but it does more than that and its been, I found out there is a lot of truth. Have you ever seen zombie movies, right? When you boost the immune system and when you trigger the immune system in it helping individual what you are doing is you are actually increasing the dopamine levels and you are actually increasing the adrenaline in the body that help fight off the shot which is causing aggression which, its just not the COVID situation in this particular aspect. Its also the drug is causing or the vaccine is causing extreme aggression in some individuals you know, in them active immune system (Further clarification unknown hence split not made). You guys are increasing the dopamine, you are increasing the adrenaline levels and its causing increased aggression."   Follow-up: Consumer stated, "Yes, that's fine and can show them the research information that like said, it was kind of a white elephant in the room, right, When people get sick they get grumpy they get angry, right and then directly link that because what happen is you guys are triggering the immune system and so, it increases the dopamine level in the brain and it also increases you know, butterfly which is basically the adrenaline in the body which causes in some people's cases extreme aggression (Further clarification unknown)." Healthcare Professional: Consumer stated, "Well, I am Ex-healthcare professional. I was in biological and chemical warfare officer and I was a certified EMT (Further clarification unknown, hence captured as consumer or other non-health professional in tab)." LOT#: Consumer stated, "The LOT#I received it just through the clinic. I can't give you a specific LOT# to it. Yeah, it was the booster shot through the VA. It was the Pfizer booster shot through the withheld." Expiration Date and NDC#: Consumer stated, "No, I am sorry. I got mine through the VA, 'again' the health subject was basically me but I also noticed that within a group of veterans that it was causing extreme aggression in certain patients (Further not clarified, hence split not made) and what I found out in the study that I did was basically within healthy individuals or active immune systems, when you inject them with the antibodies what you are doing is you are also increasing the dopamine levels and you are also increasing the adrenaline in the body that fight off the shot which is causing in some cases and like I said, it's only within the individuals with extreme active immune systems (Further clarification unknown). Does that make sense?" Date of Birth: Consumer stated, "withheld (Not appropriately clarified hence not captured in tab)." Age when adverse event started: Consumer stated, "I am 54 (years) and that's the other thing I noticed too that the effects are only within the older individuals and I don't know what age I haven't study that a 100%. I mean, there is a lot to those research that needs to be done but I noticed that within older individuals and I think age plays a part into triggering the aggression." Gender: Consumer stated, "Well, actually my gender is, I was born androsex but yeah, I am legally female."  Vaccination Facility Name: Consumer stated, "It was through the #." Telephone# and Mailing Address: Consumer stated, "You could send it in, # hospital." Facility Type: Consumer stated, "It is a hospital pharmacy, its general veterans care." Date of vaccination: Consumer stated, "I got the booster. I had the two shots before that and I got the booster a week ago on Thursday. It would have been 9Nov. I think it was Thursday. Yeah, it was November the 9th of whichever day it was Thursday." Anatomical site of vaccination: Consumer stated, "In the shoulder, in the left shoulder." Medical Conditions and Concomitant Medications: Consumer stated, "No, generally no. I am just taking Vitamins and I take Vitamin D."  Lab Test: Consumer stated, "Yeah, like I said, I was born androsex. So, when lab came back it showed increased adrenaline and dopamine and so, it was kind of bizarre chance because they do my blood work for hormones. If that make sense?" (Further clarification unknown) Treatment: Consumer stated, "Basically my psychologist prescribed a mild tranquilizer."  Prior Vaccination Within four weeks): Consumer stated, "No, just the two shots that were 4 weeks apart which was back in February I think February and beginning of March right now. I mean, that's pretty close. It just so happen because I am, was born androsex when they did the blood work you know, its just happened to be an odd chance that I caught up because when they did the blood work for my hormone because I was born androsex they noticed increased really high levels like I said, dopamine and adrenaline." Prior Vaccination (Confirmation): Consumer stated, "Right, after years, years and years." Route of Administration: Consumer stated, "Intramuscularly. Yeah, they shot it right into my shoulder into the, I don't know what did they call that muscle in the shoulders. It hurt like hell but they know it I think they know that, but I don't think they know that its also increasing the dopamine and the adrenaline." When probed for any further help, consumer stated, "No, I just wanted report it."  QR Comment: This is a split case however further details of other patients were not available over the call, hence split case was not made.  The lot number for the vaccine [BNT162B2] was not provided and will be requested during follow up.  The lot number for bnt162b2 was not provided and will be requested during follow up.