her MS symptoms exploded; head became foggy; blurred eyes; slight headache; This is a spontaneous report by contactable consumer(patient) from Pfizer Sponsored program.  A 68-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) first dose on 17Mar2021 at single dose for COVID-19 immunization. Medical history included Multiple Sclerosis (MS) for 20 years and autoimmune disease. Concomitant medications included interferon beta-1a (AVONEX) for MS. The patient previously took Avelox for MS. Caller also states she would like to report that she has a history of Multiple Sclerosis (MS) and she goes to the clinic. Caller states since no studies were done on people with MS, she would like to report her experience. Caller states she received her first dose of the vaccine on 17Mar2021 and hours afterwards her MS symptoms exploded. Caller states she has had MS for 20 years and she doesn't even realize she has it because she is able to walk the dogs at the pound and she does 3600 steps a day and it doesn't keep her from doing anything. Caller states after the shot she has torn meniscus in her knees and her knees were so tight and she has heel spurs, and they were burning and hurt. Caller states she hurt her hand previously and her hand was tight, and it felt like it was going to explode. Caller states every injury she has ever had it felt like it was exacerbated and got worse. Caller states she was instructed by the Clinic to take Tylenol every 6 hours and these symptoms lasted for 12 days. Caller states she takes a medication called Avelox for MS once a week and she didn't take it after the shot because it is known to cause flu like symptoms, but she is back taking it now. Caller states she was working on the computer and her head became foggy and this lasted for six or seven days. The caller has MS and is on Avonex, it's a beta 1 interferon injectable that she has been taking for over 20 years. The caller's doctors told her it was okay to get the shot. Because of the caller's autoimmune disease, the caller's doctors don't know how effective the shot will be with an autoimmune disease. The caller has done well with Multiple Sclerosis; her Multiple Sclerosis was really good she was walking 3600 steps a day. The vaccine seems to have flared up everywhere the caller has been hurt. It made those spots worse. The caller had a torn meniscus and it felt like her knee was stiff like a board. The caller had a bone spur in her foot that it began to hurt where that was removed. The caller broke her left hand and then it felt like it was going to explode. The caller also had head fog and blurred eyes. It took 6-7 days for head fog to get better. The other symptoms it was 12-13 days to get better. The caller also had a slight headache. The clinic said there were no studies in someone with MS who took the covid vaccine, they only reported to them about the autoimmune disease. Someone on the thing said the second dose was 10 times worse than the first one. Then the caller was told if she gets those symptoms with the first shot then the second one will be better because your body is used to it and knows what to do. It is kind of like a trial by fire and no one knows what to expect. The caller wants to know if Pfizer had any information on Avonex interfering with MS. The outcome of the events was unknown.  Information on the lot/batch number has been requested.