feeling "very tired"; rash on the "covid arm",; rash on her chest; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 71-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), as dose 4 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation; palbociclib (IBRANCE), at 75 mg. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose 1), for Covid-19 immunization; Bnt162b2 (Dose 2), for Covid-19 immunization; Bnt162b2 (Dose 3), for Covid-19 immunization. The following information was reported: FATIGUE (non-serious), outcome "unknown", described as "feeling "very tired""; VACCINATION SITE RASH (non-serious), outcome "unknown", described as "rash on the "covid arm","; RASH (non-serious), outcome "unknown", described as "rash on her chest". The action taken for palbociclib was unknown.  Additional information: The patient called to ask about the interaction of Ibrance 75 mg tablet and Pfizer Covid19 vaccine booster dose. The patient stated that she was on a "cancer protocol" and she was taking Ibrance 75 mg tablets for this. She mentioned that she recently received the Pfizer covid19 vaccine and had a reaction with it. She wanted to know if there were any interactions between the Pfizer covid vaccine and the Ibrance tablets. She further explained that she previously received 3 doses of the Pfizer covid19 vaccine and this was her 4th dose, 2nd booster dose specifically. She added that she did not have any reactions from her 3 previous doses, only for this dose as she started taking Ibrance at the time on the vaccination. She mentioned that she developed rash on the "covid arm", the arm where she received the vaccine, and rash on her chest as well. She also said that she was feeling "very tired" after receiving the vaccine. The patient said that she only experienced this after being on Ibrance medication when she received the second booster dose (Pfizer COVID-19 Vaccine). The patient stated "I got it Friday, last Friday the what the date was but it was last Friday, and I got later last night the rash on my arm and then that rash fade up and filled may be Yesterday. Morning, it started to get black and then I got the rash on my upper chest and then the next night the, the last night or other night before I got another rash on the left side of my upper chest." The patient further stated, "I am calling to get help for myself to find out information and now I am giving you every information, I am just frustrated, and I have been on the phone for now. Yes, I am just trying to find out what's anything that I am taking the Ibrance and having me rashes and being tired that all I wanted to know, now I am closed up answering you. I am frustrated right now. I am just going to quiet this (call). I am getting too frustrating, and I don't feel, like I have only want to having all this information and nobody answered my question."  The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 has been requested and will be submitted if and when received.