She started itching a lot/scratching everywhere, mainly her arms/ Her legs itch, her feet, and the soles of her feet./ mostly in her hands, arms, and upper legs; feeling chills.; couldn't go back to sleep.; scratching everywhere/ little cuts from scratching/ she would scratch; It feels like the nerves are at the edge of her skin; The initial case was missing the following minimum criteria: No adverse effect. Upon receipt of follow-up information on 21Sep2020, this case now contains all required information to be considered valid.  This is a spontaneous report from a Pfizer-sponsored program. A contactable consumer (patient) reported that a 73-year-old female patient of an unspecified age received pneumococcal 13-val conj vac (dipht crm197 protein) (PREVNAR 13, NDC: 0005-1971-01), via an unspecified route of administration on 20Sep2020 at 0.5 ml single (half a milliliter prefilled syringe) for pneumonia vaccine. Medical history included nickel: allergies, lead: allergies from an unknown date and unknown if ongoing. There were no concomitant medications. The patient previously took formaldehyde, phenols, quaternium-15, zinc and experienced allergies. She has never received a pneumonia vaccine but had a terrible reaction to the flu vaccine influenza vaccine (FLUZONE) because of the 5 micrograms of formaldehyde per 0.5 ml sample. The patient experienced started itching a lot/scratching everywhere, mainly her arms/ her legs itch, her feet, and the soles of her feet./ mostly in her hands, arms, and upper legs, feeling chills both on 20Sep2020, couldn't go back to sleep on an unspecified date. Caller received the pneumococcal 13-val conj vac (dipht crm197 protein) injection yesterday afternoon. She didn't know for sure but she started having a reaction. She had never had this reaction to anything. She started itching a lot. The itching wasn't too horrible being awake, but once she went to bed it was worse. Within in an hour she woke up scratching everywhere, mainly her arms. She even had little cuts from scratching. She got up and took a hot bath too. She also was feeling chills. She was cold and itched. That was why she thought getting in the hot bath would help. She also tried taking diphenhydramine hydrochloride (BENADRYL). She thought maybe it would help. It wasn't as bad after that, but she couldn't go back to sleep. She would try to lie down, but she would scratch. She was up most of the night. She doesn't know. She was still feeling itchy. When she was awake the itching was not so horrible. It was like it was coming from the inside and coming out of her. Her legs itch, her feet, and the soles of her feet. She did have a lot of allergies. She did call and check with Pfizer before getting this to make sure it didn't have Formaldehyde, Quaternium-15, or phenols in it. They are her worst allergies. It didn't have those in it so she decided to get it. She didn't know what it could be. There may be another allergy she was not aware of. She was a chemist until she retired, and she had some strange allergies. She has never had this type of reaction with her other allergies. Usually those are breathing allergies. The itching and chills started an hour after the vaccine. It had improved some. Now it was mostly in her hands, arms, and upper legs, before it was everywhere. After the bath, she had a cream that was from Dermatologist a while ago. It was Triamtinolone acetonide steroid cream 0.1%, she used that as well. She put that on the places that were itching. When she would put that on, she could finally go back to sleep. She received the vaccine at pharmacy. When she checked to get information originally to be able to get it, they gave her a paper then. She doesn't know if it was the same lot of what she actually got. The lot wasn't listed on her papers. She has never had a pneumonia shot. She hadn't been able to take flu shots in recent years, but she was told this particular flu shot called fluconazole (FLUCOMAX) she could get. She took that 3 weeks ago. Someone told her when she got that shoot that one of the Pneumonia shots didn't have what she was allergic to. It was pneumococcal 13-val conj vac (dipht crm197 protein). She called Pfizer to find out if the things she is allergic to were in it, and they were not. She did her research on it. She had never had a Pneumonia shot. She has had some itching in her hands before this, but nothing like this. The hands were giving her a little trouble before. She had been using that steroid cream periodically. She cannot determine what she was allergic to sometimes. She is allergic to liquid hand soaps. She hoped it quits. This was not one of her normal reactions. Her hands did this odd thing again with the itching. The itching was everywhere. It feels like the nerves are at the edge of her skin. The doctor said she shouldn't take anything like this. So he doesn't know she got it. The outcome of events for started itching a lot/scratching everywhere, mainly her arms/ her legs itch, her feet, and the soles of her feet/ mostly in her hands, arms, and upper legs was resolving, for feeling chills was not resolved, for other events was unknown.  No follow-up attempts are needed. Information on Batch number, Lot number cannot be obtained.