2nd dose was not taken from a bottle, but was already prepared in a syringe on the table; redness at the vaccine site/redness and puffiness at injection site; puffiness/redness and puffiness at injection site; painful; she put water on it, it got worse; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 54 year-old female patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (1st dose), for COVID-19 immunisation, reaction(s): "she had problems breathing", "puffiness and redness", "very tired", "pain in her leg and her hand", "puffiness and redness", "strange flavor in her mouth".The following information was reported: CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR (non-serious), outcome "unknown", described as "2nd dose was not taken from a bottle, but was already prepared in a syringe on the table"; VACCINATION SITE ERYTHEMA (non-serious), outcome "unknown", described as "redness at the vaccine site/redness and puffiness at injection site"; VACCINATION SITE SWELLING (non-serious), outcome "unknown", described as "puffiness/redness and puffiness at injection site"; VACCINATION SITE PAIN (non-serious), outcome "unknown", described as "painful"; CONDITION AGGRAVATED (non-serious), outcome "unknown", described as "she put water on it, it got worse".  Additional information: The patient was calling about the vaccine, the Pfizer Covid vaccine. Caller had second vaccine on Sunday and after a day or two noticed redness and puffiness near the injection site. She wants to know if it's ok. She wants to know what to do. She's sure other people experience redness but she wants to know if she can shower and put water on it. Is it ok. After the first vaccine she had problems breathing. 15 minutes after vaccine then she had problems the whole day. She had a very strange flavor in her mouth. Like a strange flavor. She had pain in her leg and her hand and leg was very painful. It was her left hand on the side of the injection and both legs. And she had very strange flavor in her mouth for few days after she ate. Also puffiness and redness after vaccine. And also she was very tired. When querying information about Covid vaccine card for NDC/Lot/Expiry she asks can she use the card to go on airplane. She will have to call the airline. When she got the second shot it was from the bottle and it was on the table. He (the person administrating it) had the bottle on the table and he showed me the Pfizer sticker. With the first vaccine she doesn't have any bottle. It was a lot of people and it was very crowded. The vaccine was there, it was already there and she didn't know how long it stood there. She wants to know if it's ok if its prepared ahead of time. She usually sees them pull it out from a bottle but it was already prepared and she doesn't know if that's ok. How long was it there.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.