Fingers on right hand are swelling; Rash is all over her abdomen and back and it itches/generalized purities with skin rash; Severe itching/it was a pruritus; Severe urticaria on her body with welts/Welts on her torso, legs, and arms/hives/generalized urticaria; Redness; fever/fever of 100.; This is a spontaneous report from a contactable nurse (patient) from a Pfizer-sponsored program COVAX US Support.  A 64-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 intramuscular, administered in Arm Left at age of 64 years on 22Mar2021 10:50 (Lot Number: EL9267) as dose 2, single for covid-19 immunisation. Medical history included allergic to Sulfa, at 22 years old she had an experimental drug and she had an anaphylactic reaction at that time. She was given epinephrine. She has no food allergies. She didn't recall the reaction she had to the Sulfa medication. The experimental drug, she doesn't recall the name, it caused her face to blow up, she had hives and she couldn't open her eyes because of the swelling. Concomitant medication included ongoing thyroid (ARMOUR THYROID). Historical vaccination included shingles shots 2 injections and sick for a day with both injections then it went away; Flu vaccine; received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 1 at age of 64 years on 01Mar2021 10:50 A.M. (Lot number: EL9269) for covid-19 immunisation and had no side effects. No vaccines administered on same date with the Pfizer vaccine considered as suspect. No vaccinations (within 4 weeks). No vaccines for any other conditions prior to the event. No vaccines for SARS-CoV2 other than Pfizer-BioNTech COVID-19 Vaccine prior to the event. The patient has not received any other vaccines around the time of Pfizer-BioNTech COVID-19 Vaccine vaccination. On Monday, 22Mar2021, patient received second covid vaccine dose and "weird things happened". Patient felt ok on Monday after getting the shot, Tuesday, 23Mar2021 at 3 am she experienced a fever, "it wasn't much and went away in about 4 hours". On Wednesday she was fine and then Thursday (25Mar2021) afternoon around 3 she developed "itching, urticaria all over legs with welts, very itchy over whole body". And then having another fever of 100 (2021). Patient knew it was typical to have a fever after receiving the Covid 19 vaccine. Early Tuesday morning, 23Mar2021 at around 3:00AM she had a fever for about 4 hours then she was fine. On Thursday afternoon, 25Mar2021, she developed severe urticaria on her body with welts. It started slow and has progressed. She also has severe itching (since 25Mar2021). She had no fever at that time. Some of her fingers on her right hand are swelling (since 26Mar2021) she thought because she's scratching so much. She has welts on her torso, legs and arms (25Mar2021). She just now took her temperature and it was 99.8F (2021). Patient didn't know what she had and she hasn't read anything about a rash after the Covid 19 vaccine. And the rash was all over her abdomen and back and it itches (since 25Mar2021). She didn't know how or why she just got a fever. She thought it's kind of strange. She's 64 and she's had the shingles shots and she gets the flu vaccine. The first Covid 19 vaccine she had nothing. She didn't have an internist, she did have an allergist. She wanted to know what to do with this, if this was from the Covid 19 vaccine. The time frame didn't seem right to her. The rash started on Thursday, 25Mar2021 at around 3:00 or 4:00PM. The rash changes, it migrates. She thought it's gotten bumpier. She will call her allergist on Monday, 29Mar2021. The patient initially reported adverse events after taking the 2nd dose (systemic body reaction - pruritus, redness (25Mar2021)) but has a question about what to do regarding her booster shot. Patient took a second shot of Pfizer COVID 19 vaccine in Mar, stated she believed she was due for a booster till Oct or Nov, 6-7 month mark. Patient severely broke out she had a reaction 3 days after she took a second shot and she didn't know what to do with a booster. Patient further clarified symptoms: this was more than a rash when her husband who was a physician has to call the ER, because she was in the severe discomfort from head to toes, it was all over it was a pruritus with welts all over the place, she was bad the welts did not go away for a week and a half she got steroids for 3 days and it did help but when the steroids would wear off after about 8 hours then she began to get the same craziness that she had gotten before which was a severe , severe itching coming from inside out, not topical, it was topical but it was not like any other itching that she had ever experienced in life and it was just that bad she was screaming in her own house so the thought about taking another dose, booster shot was a problem. The patient experiended rash, hives, welts, swelling of fingers, itching, had generalized urticaria and generalized purities with skin rash. The patient was not hospitalized, not admitted to an Intensive Care Unit. Events fever, fingers on right hand are swelling, rash is all over her abdomen and back and it itches, severe urticaria on her body with welts, severe itching, welts on her torso, legs, and arms related to covid-19 Vaccine. Therapeutic measures were taken as a result of rash, pruritus, welts and included treatment with steroids. The outcome of the events was not recovered.