can't pick one leg upon the other; short of breath; Lethargic; Difficult to breathe; Feet and lower legs are swollen; So exhausted; This is a spontaneous report from a contactable consumer (patient). A 60-year-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: EW0173, Expiration date: 31Aug 2021) via an unspecified route of administration, administered in right arm on 13May2021 (at the age of 60-year-old) as dose 1, single for COVID-19 immunization. The patient had medical history of ongoing Diabetes mellitus from unknown date of 2006 and ongoing Cerebrovascular accident from 14 Mar 2020 and ongoing, Narcolepsy from unknown date and ongoing from an unspecified date of Nov2019. Patient concomitant medications included ongoing ergocalciferol (VIT D [ERGOCALCIFEROL]) 5000 units once daily taken for Nutritional health, from an unspecified date of 2020. Ongoing clopidogrel 75 mg ,1x/day taken for year ago in 2020, metformin taken for Diabetes mellitus on unspecified date, glipizide taken for Diabetes mellitus on unspecified date of 2020. Ongoing Atorvastatin taken for unspecified indication of unspecified date of about a year ago in 2020. Ongoing Armodafinil is taken for Narcolepsy on unspecified date of 2020. Ongoing apixaban (ELIQUIS) is taken for Blood thinner, Eliquis in May2020 or Jun2020 on unspecified date, ongoing Lisinopril taken, she began taking Lisinopril in May2020 or Jun2020 on unspecified date. Ongoing Hydrochlorothiazide 12.5 mg, 1x/day is taken for Don't know, think it's a water pill, she began taking Hydrochlorothiazide in May2020 or Jun2020. Ongoing Nifedipine began taking Nifedipine in May2020 or Jun2020, ongoing Metoprolol succinate in May2020 or Jun2020. Prior Vaccinations, the patient was not received within 4 weeks. Reporter is a patient calling in regards to the Pfizer Covid-19 vaccine. She reported that she received the first dose of the Pfizer Covid-19 vaccine yesterday, 13May2021. She reported that her feet and lower legs are so swollen that her toes have very minimal use. she reported that she couldn't wiggle her toes because her feet are so swollen and can't pick up one leg onto the other leg because her legs are so tight. she inquired if she should go to the doctor or hospital. She reported that now, at time of call on 14May2021, she is so exhausted. She reported that it's difficult to breathe and she is out of breath. reporter reported that it was hard to keep her eyes open because she was so exhausted at time of call on 14May2021. She reported that she received the first dose of the Covid-19 vaccine around noon time on 13May2021 and got home around 3:00 PM. She reported that her feet and legs started swelling after that. Reporter reported that the difficulty breathing and feeling out of breath began about half an hour on 14May2021. She reported that she began feeling lethargic on 14May2021. Investigations included she reported that the last calcium score for her heart was 351. She reported that her blood pressure that she took this morning, 14May2021, was 134/70. The patient underwent laboratory tests reported that the last calcium score for her heart was 351. Her feet and lower legs are very swollen, she cant pick one leg upon the other, she also feels short of breath and she feels so exhausted that she can barely keep her eyes open. She would like to know what should she do if she should go to the doctor. During the transfer she said that she was feeling very exhausted in that moment (she took that information in her report). The outcome of events feet and lower legs are swollen, so exhausted was not recovered rest other events was unknown.  No follow-up attempts are needed. No further information is expected.