Swelling in hands are still there and it is frustrating; Joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders was reported as worsened; swelling in every joint in her body/ Joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders; Swelling in hands are still there and it is frustrating; began experiencing swelling in her bilateral knees; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team for a Pfizer sponsored program. The reporter is the patient.  A 52 year-old female patient received bnt162b2 (BNT162B2), administered in arm right, administration date 22Dec2021 (Lot number: 33025BD) at the age of 52 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Gestational Diabetes" (unspecified if ongoing), notes: Gestational Diabetes 10 years ago and it has resolved.; "She has allergy, slight, to garlic", start date: 2020 (unspecified if ongoing); "diagnosed allergies" (unspecified if ongoing); "obesity" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose: 1, Lot EW0158, expiration is unknown, Anatomical Location: Injected into left arm), administration date: 15Apr2021, when the patient was 51 years old, for COVID-19 immunization; Bnt162b2 (Dose: 2, Lot EW0173, expiration is unknown, Anatomical Location: Injected into left arm), administration date: 10May2021, when the patient was 51 years old, for COVID-19 immunization; Flu (Manufacturer: Unknown, Lot Number: Unknown Route, Anatomical Location: Injected in left arm. , No. of Previous Doses: not provided (with in four week).), administration date: 30Nov2021, when the patient was 52 years old, for Immunization. The following information was reported: JOINT SWELLING (non-serious) with onset 26Dec2021, outcome "recovering", described as "began experiencing swelling in her bilateral knees"; JOINT SWELLING (non-serious) with onset 11Jan2022, outcome "not recovered", described as "swelling in every joint in her body/ Joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders"; PERIPHERAL SWELLING (non-serious) with onset 11Jan2022, outcome "not recovered", FRUSTRATION TOLERANCE DECREASED (non-serious), outcome "unknown" and all described as "Swelling in hands are still there and it is frustrating"; CONDITION AGGRAVATED (non-serious), outcome "unknown", described as "Joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders was reported as worsened". The events "began experiencing swelling in her bilateral knees", "swelling in every joint in her body/ joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders", "swelling in hands are still there and it is frustrating" and "joints swollen in wrist, hands, fingers, ankles and pretty much all joints, except elbow and shoulders was reported as worsened" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of joint swelling, joint swelling, peripheral swelling, condition aggravated.  Additional information: She had Knee swelling on both knees and went to an orthopedist because she thought she had been skiing and the swelling might have something to do with that. She saw him on 06Jan2022, and he told her to take ibuprofen and rest and don't exercise, then follow up in 2 weeks. Then, she went for follow-up and then between time she saw and follow up, wrist, hands, fingers, ankles, and pretty much all of the joints except elbow and shoulders all were swollen. Knee swelling improved after 3 weeks of steroids. This started 2 weeks after her knee, probably. It was very subtle on 11Jan2022, and then it got really bad on 16Jan2022 and could not see her bones in her hands. It has been 8 weeks later. She said she would have rather had COVID. She has not had COVID and had friends that did not have swelling 8 weeks later. She went to the Orthopedist twice and had an initial and follow up to which he said to go to a Rheumatologist and she made an appointment with one. It is really hard because maybe a lot of people are having adverse reactions. She gave her a week of Steroids of a taper dose, 6,5,4,3,2,1. The rheumatologist said it was too high of a dosage and too drastic of change. The very next day, they swelled up again. Even though it was a high dose, she felt completely normal. On 11Feb2022, she started her back on steroids and she is still swollen and going for another follow up. The one she is taking now is Prednisone. She was taking 10mg a day and now she increased to 20 and it is still not doing it. It is in a pharmacy vial with no lot or expiration. She just thinks it is not a high enough dose. Initially she wanted her to take 2 of the 5mg and does not know what she will do now, since she is still swollen. She was supposed to take 10mg, and she said email her if swelling is not going down, so she wrote her back and said to increase to 20mg, or 4 tablets. The initial steroid from her Primary Care was Methylprednisolone, 4mg, 21 of those. First day, she was to take 6, and then taper down from there. It was a blister pack. She threw it away and no longer has the lot or expiration or a sample to send. It was sealed and intact. She gave her the 60 count, because she knew she would be tapering her. List other relevant diagnostic and confirmatory test results for event(s), for example, from blood tests, cerebro-spinal fluid culture, pleural fluid culture, urine culture, diagnostic imaging, (e.g., chest X-ray, MRI)Test: Date: Result: Units: Normal Range: Low: High: Patient was on Prednisone 10mg daily and she was still having swelling, so the doctor had to increase the dose to 20mg daily. She said it was not that it wasn't working, but just that the dose was not high enough. She is still swelling even after taking 20mg daily. They are all the 5mg dose from the bottle. It was in a pharmacy vial with no lot or expiration. She gave her the 60 count, because she knew she would be tapering her. Product strength and count size dispensed: 5mg, 60 count. The initial steroid from her Primary Care was Methylprednisolone, 4mg, 21 of those. She said she felt completely normal while taking, but as soon as she stopped, the swelling returned. She had to go back to a Rheumatologist and he prescribed Prednisone. First day, she was to take 6, and then taper down from there. It was a blister pack. She threw it away and no longer has the lot or expiration or a sample to send. Product strength and count size dispensed: 4mg, 21 count. Yes the packaging sealed and intact.  Follow-up attempts are completed. No further information is expected.