the Pfizer Covid 19 vaccine has been affecting her cycle; Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots; Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots/affecting her cycle/significant iron drop; last April she was at a 5 for her ferritin prior to the shots and now is a 5.7.; fatigued; needed to take naps and not feeling really well; chest pain, left discomfort; back pain; left arm discomfort; chest pain, left discomfort; palpitations; significant iron drop; strange phlegmy cold; Cough/throat clearing cough thing but nothing like it was; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 51-year-old female patient received BNT162b2 (BNT162B2), on 26Nov2021 as dose 3 (booster), single (Lot number: 33030BD) at the age of 50 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Known allergies: progesterone" (unspecified if ongoing); "fibroids" (unspecified if ongoing), notes: Later clarified that she was diagnosed with fibroids 12 years ago. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE:2, Lot: EW0162), administration date: 21Apr2021, when the patient was 49-year-old, for Covid-19 immunization, reaction(s): "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots", "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots", "April's cycle was 4 -5 days late after the shot and extremely heavy/Had more bleeding in the month of September getting three periods a month and losing an excessive amount of iron", "Had more bleeding in the month of September getting three periods a month and losing an excessive amount of iron", "last April she was at a 5 for her ferritin prior to the shots and now is a 5.7"; BNT162b2 (dose:1, Batch/lot number  : ER87:33    ,  intramuscular left arm), administration date: 26Mar2021, when the patient was 49-year-old, for COVID-19 Immunization, reaction(s): "the Pfizer Covid 19 vaccine has been affecting her cycle", "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots", "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots", "unsure if her fibroids increased in size or not", "last April she was at a 5 for her ferritin prior to the shots and now is a 5.7". The following information was reported: COUGH (non-serious) with onset Sep2022, outcome "recovering", described as "Cough/throat clearing cough thing but nothing like it was"; NASOPHARYNGITIS (non-serious) with onset Sep2022, outcome "unknown", described as "strange phlegmy cold"; CHEST PAIN (non-serious) with onset 07Oct2022, outcome "recovered" (17Oct2022), CHEST DISCOMFORT (non-serious), outcome "unknown" and all described as "chest pain, left discomfort"; LIMB DISCOMFORT (non-serious) with onset 07Oct2022, outcome "recovered" (17Oct2022), described as "left arm discomfort"; PALPITATIONS (non-serious) with onset 07Oct2022, outcome "recovered" (17Oct2022); BACK PAIN (non-serious) with onset 13Oct2022, outcome "recovered" (15Oct2022); BLOOD IRON DECREASED (non-serious) with onset Oct2022, outcome "unknown", described as "significant iron drop"; MENSTRUAL DISORDER (non-serious), outcome "unknown", described as "the Pfizer Covid 19 vaccine has been affecting her cycle"; BLISTER (non-serious), outcome "not recovered", described as "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots"; CONDITION AGGRAVATED (non-serious), outcome "not recovered", described as "Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots/affecting her cycle/significant iron drop"; SERUM FERRITIN DECREASED (non-serious), outcome "unknown", described as "last April she was at a 5 for her ferritin prior to the shots and now is a 5.7."; FATIGUE (non-serious), outcome "not recovered", described as "fatigued"; MALAISE (non-serious), outcome "unknown", described as "needed to take naps and not feeling really well". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of menstrual disorder, blister, blood iron decreased, condition aggravated, serum ferritin decreased, nasopharyngitis, fatigue, malaise, cough, chest pain, chest discomfort, palpitations, back pain, limb discomfort.  Clinical course: Caller stated that she has two questions. Wanted to know if her iron is 32 and her ferritin is 5.7 is due for the Pfizer Omicron shot on Wednesday do advise build up iron and wait or the shot should not effect her iron levels. Since its been affecting her cycle; she had the three shots and did not get a fourth booster she wanted to know when would be best time to get it. Is starting her cycle next week. With the other shots she got those during her period. What would be the best time for it. Knows the iron question is kind of tricky. Clarified that she had all three Pfizer shots. Clarified again that she had the Pfizer Covid shots. Has a progesterone allergy where she would break out in blisters on her neck way is worst after the Pfizer Covid shots. Noticed it was worst 26Mar2021. Is unsure if the Pfizer Covid shot affected her progesterone or estrogen and increased side effects or if her age is making everything come into effect. Clarified that she had the progesterone allergy before Pfizer Covid shots. Clarified that she had fibroids along with shot. Later clarified that she was diagnosed with fibroids 12 years ago. Mentioned that she is unsure if her fibroids increased in size or not that her doctor would have that information. Had first Pfizer Covid shot while cycling. April's cycle was 4 -5 days late after the shot and extremely heavy. Is at the age of peri-menopause and it is very difficult to determine if perimenopause if her hormones affected her cycle or the Pfizer Covid shot affected her cycle. Had more bleeding in the month of September getting three periods a month and losing an excessive amount of iron. Clarified that her iron was normal up until just this last blood draw. Two draws after the three Pfizer Covid shot series everything stayed the same and she had no inconsistencies at all until Sep2022. Just got her labs drawn last week. Was significant iron drop and her ferritin has been relatively low all along. Later clarified that last April she was at a 5 for her ferritin prior to the shots and now is a 5.7. Caller rambling on despite multiple attempts to redirect. Unable to clarify details.  Noticed that her progesterone allergy was worst after the first shot. Last booster was the day after Thanksgiving last year. Will be a year of having no shots in November of this year. Her chest pain irregularities last week led her to get her iron drawn. Had a strange phlegmy cold early September and tested negative for Covid. Clarified it as she was very fatigued, needed to take naps and not feeling really well for at least a week ago. Was not hungry and all those things. Cough and chest pain went away and she showed up with back pain. Clarified that the cough started the first week in Sep. Now she has a throat clearing cough thing but nothing like it was. Fatigued was the first week of Sep2022. Had chest pain, left discomfort, palpitations and the EKG came back normal. Chest pain started around 07Oct. For 12 hours her lower back was killing her.  Follow-up attempts are completed. No further information is expected.