Aortic Calcification; Coronary artery Calcification; The only unfavorable reaction was very slight soreness at the injection site the first 24 hours; One positive effect was that one viouse sore, joint on right arm-poss inflammation of joint was improves and soreness disappeared. It may help reduce inflammation; This is a spontaneous report from a contactable consumer (patient). An 81-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 Vaccine, Batch/Lot number was not reported), dose 2 intramuscularly, administered in arm left on 11Feb2021 08:30 as a single dose for COVID-19 immunization. Medical history included High blood pressure disorder on 15Sep2014; COPD (Chronic obstructive pulmonary disease) on 02Feb2015; Lung nodule COPD- Lung nodule biopsy from 2017 to 2017 (ongoing); Tobacco abuse, in remission on 13Jan2018; Contraction of palm on 23Jan2018; High cholesterol on 15Sep2014; Enlarged heart on 11May2015; Chronic obstructive pulmonary disease, unspecified COPD type on 13Jan2018; Breathlessness on exertion on 13Jan2018; Congenital heart disease on 20Aug2019; Osteopenia of multiple sites (Osteopenia hip joint and others from 2018 to 2020 (ongoing)); Osteoarthritic due to wear and tear of joints on 20Aug2019; Dilation of thoracic aorta on 20Aug2019; Non- rheumatic mitral regurgitation on 20Aug2019; Skin cancer- sun exposure from 2000 to 2020 Basal, squamous (7 places over 20 years); Tobacco use from 1960 to 1998, bone health. The patient previously received first dose of bnt162b2 via intramuscular on 21Jan2021 08:30 am in left arm for COVID-19 immunization. The patient received Flu shot on 10Sep2020 and had sore arm slight. There was no covid prior vaccination. No covid tested post vaccination. No known allergies. Concomitant medications within two weeks included amlodipine besylate taken for high blood pressure; atorvastatin taken for high cholesterol; ASPIRIN [acetylsalicylic acid] taken for high blood pressure; calcium, colecalciferol (CITRACAL CALCIUM PEARLS + D3) taken for Bone Health; chondroitin sulfate, glucosamine hydrochloride (OSTEO BI-FLEX) taken for joint health; all from approx. 2011 and ongoing; Eroc Multivitamins for general health from approx. 2000 and ongoing; GNC multivitamin without iron. There was no other vaccine in four weeks. The only unfavorable reaction was very slight soreness at the injection site the first 24 hours on 12Feb2021. However as weird as this seems, the positive and favorable reaction she had was an almost complete reduction of the pain she had been experiencing since July in her right shoulder joint. However 24 hours later an arthritic right shoulder joint was improved (totally) Jan through Mar. 24 hours after the first vaccine the pain she had been experiencing since July when she lifted her right arm and moved it in a counter-clockwise 360 degree circle, had been reduced about 90% and the movement was no longer painful. The joint is not 100% but much improved. One positive effect was that one viouse sore, joint on right arm-poss inflammation of joint was improves and soreness disappeared. It may help reduce inflammation on an unspecified date in 2021. The patient also experienced aortic calcification on 22Feb2021; Coronary artery calcification seen on computed tomography on 22Feb2021. Relevant tests included blood test on 10Sep2020; Covid test on 11Aug2020: negative; antibody test on 11Aug2020: negative. Lung CT: No Change on 10Sep2020. The outcome of events was unknown.   No follow attempts are possible. No further information is expected.