Got so sick, first time was like 9 days; Thyroid rose; This is a spontaneous report from a contactable consumer (patient). This case is the first case out of the two cases.  A 57-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot Number: ER8731), dose 1 via an unspecified route of administration, administered in Arm Right on 19Apr2021 (at the age of 57-years-old) as dose 1, single for covid-19 immunisation; levothyroxine (LEVOTHYROXINE), route of administration, start and stop date, batch/lot number and dose were not reported for an unspecified indication. Medical history included CDC on Mar2020, Rash, thyroid and hypothyroid. She have been on the same dose for years and years and years under Thyroid medicine. Family history included Guillain Barre syndrome, have had a family patient with the, that had that of 'Guillain Barre syndrome'. She reported about her Thyroid and also she had a hardware on her neck like she had a plate and sixth screws and that also caused the same thing. Concomitant medication included pancreatin (CREON). Historical Vaccine included Flu shot. When the pandemic first came out the patient got a flu shot and haven't had it like for 10 years. The patient experienced got so sick, first time was like 9 days on an unspecified date, thyroid rose in 2021. The patient underwent lab tests and procedures which included blood test: unknown in 2021 for blood work and my Thyroid was totally messed up, thyroid function test: rose really at a whack in 2021 Thyroid rose really at a whack and that was after my first dose.  Therapeutic measures were taken as a result of thyroid rose. The patient reported that she was first got diagnose in Mar2020 and her doctor had actually called CDC. She had been sick for few weeks but she did not realize the symptoms until they asked about a rash and she had a big rash and she had gone to see her doctor just for a normal appointment and they called the CDC and sent her for testing. The patient went to the hospital for test, in Mar2020 and the hospital said denied her saying if she has severe breathing problems test would be done. In Dec2020 she got very sick again without any symptoms and she actually went and got tested and then it said negative but she felt sick just like the first time. She went to her doctor and so she put her on like the steroid, Dose Pack and Z Pak (treatment) and within several days, and then she also put her on something Cream for the rash and felt within a week or 10 day, she was better. She got COVID 19 shot and she got so sick. No treatment was received for the events. She reported time of vaccine administration as 01:11 or 01:12. She reported that she was on Levothyroxine for Thyroid which they really had to increase right after the first dose. The first time was like 9 days and I was like if I have a better shot, it has to better than that but not the second shot and so I went. I had always been on Thyroid medicine (Levothyroxine) for like a year but it was totally out of range (PC Filed Conservatively) and so they had to increase the dosage because she had hypothyroid. Patient also wanted to report about her mother's symptoms because she thought, it was messing up the Thyroid and stuff. She reported, she had both the doses. She helped her son to had his first dose. The patient reported that she was an occupational therapist. The patient said the first day she got the first vaccine. She has wrote down everything from the first and got whole diary of it. 19Apr2021 She had symptoms for 9 days and then her second dose she got on 10May2021. Then she really had bad symptoms from 10May to 20May, 19. The patient reported she lost like 10 pounds in the past 4 weeks because they increased her Thyroid medicine. She currently was at 112. When probed if she took any vaccination 4 weeks prior to COVID 19 Vaccine, she stated, about her flu shot, it was in September prior to. The one thing that really stuck her so weird down was that her mom totally screwed up after and she got totally different, She got the J & J when and she doesn't flaunt her but her thyroid totally messed up afterwards also. So, that was 2 things the patient got that's could be a coincidence but the patient don't thinking it's a coincidence. She went to the doctor on Monday to repack her thyroid because they tested it 2 months ago. That was from her second shot that her thyroid messed up. It was actually after the first one they just said that it's a little bit of difference then she had blood work done but the second dose really big difference. She reported it's not a coincidence but then it's all something to do with the vaccine itself. She said a lot of people don't report but since she have been in healthcare profession for so long, she wanted to report it because she think every finding they have it's going to help some way or the other. She said she was just trying to give information about what her experience was and just trying to give information so they can compile information. Outcome of the event were unknown.  Follow-up (18Aug2021): Follow-up attempts are completed. No further information is expected.