he has Parkinson's Disease, and knowing the symptoms, it included most of these but not all, but his have gotten worse; Tremors of hands, feet, and legs; muscles are weak and he has trouble with balance especially when he gets up, and it is more pronounced; muscles are weak and he has trouble with balance especially when he gets up, and it is more pronounced; excessive sweating, he just gets soaked some nights. States he doesn't run a fever; Muscle cramps; when tried to move or get up in bed at night, he was frozen and couldn't move; This is a spontaneous report from a contactable consumer (patient). This consumer reported similar events for 2 patients; this report refers to the events for the reporter with both dose 1 & 2 of BNT162B2.  A 81-year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE), dose 1 via an unspecified route of administration, in left shoulder on Feb2021 (Batch/Lot number was not reported), and dose 2 on Mar2021; both as a single dose,  for COVID-19 immunisation.  Medical history included ongoing Parkinson's disease (diagnosed 20 years ago) and ongoing high blood pressure (controlled with medication; diagnosed 30 years ago). Concomitant medication(s) included Levodopa, Carbidopa, taken for Parkinson's disease, start and stop date were not reported. He takes lots of medications but stated the one that would be relevant was the Carbidopa Levodopa.  The reporter stated he had some fairly serious symptoms since his shots. He had both vaccines a few weeks apart (specified as 3 weeks apart). The first one started his symptoms out mildly, but after the second vaccine, on days 2,3,4 each day they got worse. His symptoms were tremors of hand, feet, legs and when tried to move or get up in bed at night, he was frozen and couldn't move (Feb2021). He commented "it was really scary." His muscles were weak and he had trouble with balance especially when he got up (onset Feb2021), and it was more pronounced. Stated he also had muscle cramps and excessive sweating, he just got soaked some nights (onset Feb2021). He didn't run a fever, so he didn't think he has the virus. He had chest pains occasionally, especially when in bed (onset 28Mar2021). He thinks it is lung pain, not heart; he has had both pains and it feels different. The chest pains are associated with shortness of breath (onset 28Mar2021). Stated when he couldn't turn over, he was laying on his side and that didn't help his breathing. He commented that he has Parkinson's Disease, and knowing the symptoms, it included most of these but not all, but his have gotten worse. They do blood pressure tests every morning to monitor and temperature checks and he never had a fever during that period, never had anything higher than 97 range. States he had a little bit of adverse effects after the first vaccine in Feb2021 but the main symptoms, the severe tremor and frozen all worsened after the second vaccine in Mar2021, about the second day after the second injection. There was no Emergency Room  visit; they asked him about going and they were considering it when had the frozen muscles and couldn't move . There was no Physician Office visit;  he talked to both his primary doctor and his Parkinson's doctor, over the phone and they recommended changes in the medication but he  hasn't started them yet. The outcome of the events Tremors of hands, feet, and leg, when he tries to move or get up in bad at night, he is frozen and can't move, muscles are weak and he has trouble with balance especially when he gets up, and it is more pronounced, and Muscle cramps, and Parkinson's Disease/ gotten worse, are not recovered. The outcome of the excessive sweating was unknown. The patient further commented "maybe there needs to be a warning for people with Parkinson's because they both have had rather strong reactions." Stated people with Parkinson's disease should be able to make an informed choice; maybe it was just a strong reaction to the vaccine but they should have that information.   No follow-up attempts are possible; information about lot/batch number cannot be obtained.; Sender's Comments: Linked Report(s) : US-PFIZER INC-2021369249 Same reporter/drug, different patient/event.;US-PFIZER INC-2021370302 Same patient, different dose and event.