started having Heart problems; Had 2 strokes 1 year after 2nd vaccine; He can not work. He lost money, not being able to work; He went from healthy to sick; does not have normal functions; Almost died 3 times 30 days after 2nd vaccine; found blood clots which caused zero circulation to his legs; This spontaneous case was reported by a patient family member or friend and describes the occurrence of NEAR DEATH EXPERIENCE (Almost died 3 times 30 days after 2nd vaccine), THROMBOSIS (found blood clots which caused zero circulation to his legs), CARDIAC DISORDER (started having Heart problems), CEREBROVASCULAR ACCIDENT (Had 2 strokes 1 year after 2nd vaccine), IMPAIRED WORK ABILITY (He can not work. He lost money, not being able to work), ILLNESS (He went from healthy to sick) and LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (does not have normal functions) in a 29-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     Patient was totally healthy prior to vaccination. He never had COVID-19 Disease.    On 24-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Apr-2021, the patient experienced NEAR DEATH EXPERIENCE (Almost died 3 times 30 days after 2nd vaccine) (seriousness criteria medically significant and life threatening) and THROMBOSIS (found blood clots which caused zero circulation to his legs) (seriousness criteria disability and medically significant). In 2021, the patient experienced CARDIAC DISORDER (started having Heart problems) (seriousness criterion hospitalization). In 2022, the patient experienced CEREBROVASCULAR ACCIDENT (Had 2 strokes 1 year after 2nd vaccine) (seriousness criteria disability and medically significant), IMPAIRED WORK ABILITY (He can not work. He lost money, not being able to work) (seriousness criterion disability), ILLNESS (He went from healthy to sick) (seriousness criterion disability) and LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (does not have normal functions) (seriousness criterion disability). The patient was hospitalized for 16 days due to CARDIAC DISORDER. At the time of the report, NEAR DEATH EXPERIENCE (Almost died 3 times 30 days after 2nd vaccine), THROMBOSIS (found blood clots which caused zero circulation to his legs), CARDIAC DISORDER (started having Heart problems) and CEREBROVASCULAR ACCIDENT (Had 2 strokes 1 year after 2nd vaccine) outcome was unknown and IMPAIRED WORK ABILITY (He can not work. He lost money, not being able to work), ILLNESS (He went from healthy to sick) and LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (does not have normal functions) had not resolved.            No concomitant medication information was provided.  The reporter (father) stated that his son was totally healthy and a teacher prior to vaccination. The patient never had COVID-19 disease.  It was reported that on 27Apr2021, patient's father accompanied his son to the hospital. They cut his legs open and found blood clots which caused zero circulation to his legs. Patient started having heart problems and was in the ICU for16 days. He was wearing a special monitor for a while. Patient went from healthy to sick, and can not work and does not have normal functions. Patient is now on short term disability.  Company comment: This spontaneous case concerns a 29-year-old, male patient with no medical history reported, who experienced the unexpected, serious (life-threatening and medically significant) event of near death experience; the unexpected, serious (disability and medically significant) AESI of thrombosis (leg thrombosis) and cerebrovascular accident; the unexpected, serious (hospitalization) event of cardiac disorder; and the unexpected, serious (disability) events of impaired work ability, illness and loss of personal independence in daily activities. The events near death experience and thrombosis occurred approximately 1 month after receiving the second dose of the mRNA-1273 vaccine. The event cardiac disorder occurred on an unspecified date in 2021 after receiving the second dose of the mRNA-1273 vaccine. The events cerebrovascular accident, impaired work ability, illness and loss of personal independence in daily activities occurred on unspecified dates in 2022 after receiving the second dose of the mRNA-1273 vaccine. Approximately 1 month after vaccination, it was reported that the patient almost died three times. The patient was rushed to the hospital. He underwent a procedure where doctors 'cut his legs open' and blood clots were found which caused 'zero circulation' to the patient's legs. Treatment information was not provided. It was also reported that the patient started having 'heart problems' (unspecified). The patient was admitted in the Intensive Care Unit for 16 days, and wore a 'special monitor' (unspecified) for an unspecified period of time. No further clinical information (including details about hospitalization) was available for medical review. Treatment information was also not provided. Approximately 1 year, 1 month after vaccination, it was reported that the patient had two strokes. No details were provided regarding symptoms, clinical course, diagnostic test/s and treatment. The reporter stated that the patient was unable to work, and lost money by not being able to work. It was also reported that the patient went from healthy to sick and did not have 'normal functions'. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 29-year-old, male patient with no medical history reported, who experienced the unexpected, serious (life-threatening and medically significant) event of near death experience; the unexpected, serious (disability and medically significant) AESI of thrombosis (leg thrombosis) and cerebrovascular accident; the unexpected, serious (hospitalization) event of cardiac disorder; and the unexpected, serious (disability) events of impaired work ability, illness and loss of personal independence in daily activities. The events near death experience and thrombosis occurred approximately 1 month after receiving the second dose of the mRNA-1273 vaccine. The event cardiac disorder occurred on an unspecified date in 2021 after receiving the second dose of the mRNA-1273 vaccine. The events cerebrovascular accident, impaired work ability, illness and loss of personal independence in daily activities occurred on unspecified dates in 2022 after receiving the second dose of the mRNA-1273 vaccine. Approximately 1 month after vaccination, it was reported that the patient almost died three times. The patient was rushed to the hospital. He underwent a procedure where doctors 'cut his legs open' and blood clots were found which caused 'zero circulation' to the patient's legs. Treatment information was not provided. It was also reported that the patient started having 'heart problems' (unspecified). The patient was admitted in the Intensive Care Unit for 16 days, and wore a 'special monitor' (unspecified) for an unspecified period of time. No further clinical information (including details about hospitalization) was available for medical review. Treatment information was also not provided. Approximately 1 year, 1 month after vaccination, it was reported that the patient had two strokes. No details were provided regarding symptoms, clinical course, diagnostic test/s and treatment. The reporter stated that the patient was unable to work, and lost money by not being able to work. It was also reported that the patient went from healthy to sick and did not have 'normal functions'. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.