One of the neurologists were saying it was dementia; mother was just general fatigue; she doesn't have the same muscle tone so she used; Can't walk; mother couldn't talk; paying someone to help bath and care for her; lost a lot of weight; Mother has now fallen twice; This is a spontaneous report received from contactable reporter(s) (Nurse).  A 75-year-old female patient received BNT162b2 (BNT162B2), on 04Mar2021 as dose 2, single (Batch/Lot number: unknown) at the age of 74 years for covid-19 immunisation. The patient's relevant medical history included: "Parkinson" (unspecified if ongoing); "Gullian Barre" (unspecified if ongoing); "Thyroid" (unspecified if ongoing), notes: She had been on her insulin, thyroid medication, and metformin for years prior to all this.; "she had a stroke" (unspecified if ongoing); "memory" (unspecified if ongoing). Concomitant medication(s) included: OZEMPIC; TRESIBA; ARICEPT taken for memory impairment. Past drug history included: Insulin. Vaccination history included: BNT162b2 (Dose 1, LOT: EL9267), administration date: 11Feb2021, when the patient was 74-year-old, for COVID-19 Immunization, reaction(s): "there were no problems with the first one". The following information was reported: GAIT INABILITY (non-serious) with onset 11Mar2021, outcome "unknown", described as "Can't walk"; SPEECH DISORDER (non-serious) with onset 11Mar2021, outcome "unknown", described as "mother couldn't talk"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious) with onset 11Mar2021, outcome "unknown", described as "paying someone to help bath and care for her"; FALL (non-serious) with onset Mar2021, outcome "not recovered", described as "Mother has now fallen twice"; WEIGHT DECREASED (non-serious) with onset Mar2021, outcome "unknown", described as "lost a lot of weight"; DEMENTIA (medically significant), outcome "unknown", described as "One of the neurologists were saying it was dementia"; FATIGUE (non-serious), outcome "unknown", described as "mother was just general fatigue"; HYPOTONIA (non-serious), outcome "unknown", described as "she doesn't have the same muscle tone so she used". The events "one of the neurologists were saying it was dementia", "can't walk", "mother couldn't talk", "paying someone to help bath and care for her", "lost a lot of weight", "mother has now fallen twice", "mother was just general fatigue" and "she doesn't have the same muscle tone so she used" required physician office visit. The patient underwent the following laboratory tests and procedures: Computerised tomogram: Negative, notes: Result: negative; Unit: Not Provided; Neuropsychological test: Unknown results, notes: Date: Not Provided; Result: Not Provided; Weight: lost a lot. Therapeutic measures were taken as a result of gait inability, speech disorder, loss of personal independence in daily activities.  Clinical course: Warm transfer from (withheld) with Pfizer. Speaking with a daughter who is calling on behalf of her mother in regards to the Pfizer shot. Her mother had a bad reaction to the Pfizer shot. Clarified that caller was referring to the Pfizer Covid-19 vaccine. Mother had the adverse reaction a week after receiving the second vaccine. Caller's dad thought the change in her mother was just general fatigue from the side effects. On the seventh day after the second vaccine, mother couldn't talk or walk. Thought she had a stroke. Neuro cognitive specialist saw her and said it was definitely an adverse reaction to the vaccine. Doing physical therapy with her, paying someone to help bath and care for her. Mother has now fallen twice and has continually declined since the vaccine. Thought she had Parkinson or Gullian Barre, had her tested twice for stroke, but all that was ruled out. One of the neurologists were saying it was dementia, but that not what the neuroscientist says. Caller has never seen anything like this. Its like her mother had a stoke, she was not like that until the shot. Mother is still continent and can feed herself. Mother can't walk or talk without getting the vaccine. Taking her back and forth and rehab because mother can't do in patient rehab without being admitted to hospital. First vaccine was great, there were no problems with the first one. She has lost a lot of weight which is probably good since she can't hardly walk. Wants to rehab her and get her better. but nothing is working. In the report that the neurocognitive specialists did, the doctor put the vaccine as the Moderna covid-19 vaccine, but that was a mistake. Neurologist office had it documented right, so she didn't bother them to have it changed. Mother had a neuropsychological evaluation. Found out from the nurse practitioner) NP) at the neurologist that they were doing steroids and Gama globulins like crazy. Her mother slightly got better, but then fell again. And, she keeps falling because she doesn't have the same muscle tone so she used. Caller has had her checked for everything. No previous reaction to any vaccines. no other vaccines. Mother was on a thyroid medication and insulin. Since all this has happened, mother is now on an antidepressant, memory medication, changed insulin medications and addressed everything that could be affecting her. Had her mother's thyroid assessed, insulin assessed, put her on a blood sugar pump, switched her insulin. Caller is doing her part. She had been on her insulin, thyroid medication, and metformin for years prior to all this. Now is on Ozempic, Tresiba, thyroid medication, antidepressant, and Aricept for memory. Pfizer Covid-19 Vaccine. Dose2, Date: 04Mar2021, LOT: EN0202-writing is hard to decipher. May be ENL0202. No Emergency Room. Physician Office was yes, see formal field for PCP information. No Prior Vaccinations (within 4 weeks).   The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: As there is limited information in the case provided, the causal association between the events and the suspect drug cannot be excluded. The case will be reassessed once new information is available.  The impact of this report on the benefit/risk profile of the Pfizer drug is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees, and Investigators, as appropriate.,Linked Report(s) : US-PFIZER INC-202201104444 same suspect vaccine, different patients;