Hot flashes; Chills; This is a spontaneous report received from contactable reporter(s) (Nurse and Consumer or other non HCP). The reporter is the patient.  An 82-year-old female patient received BNT162b2 (BNT162B2), as dose 4 (booster), single (Batch/Lot number: unknown) at the age of 82 years for covid-19 immunisation. The patient's relevant medical history included: "Transient ischemic attack" (unspecified if ongoing), notes: had a transient ischemic attack  a few weeks ago,but she recovered the use of her right leg.; "high blood pressure" (unspecified if ongoing), notes: takes high blood pressure medications; "Life long smoker" (unspecified if ongoing), notes: Life long smoker. The patient took concomitant medications. Vaccination history included: Covid-19 vaccine (DOSE: 1, MANUFACTURER: UNKNOWN), for Covid-19 immunization; Covid-19 vaccine (DOSE: 2, MANUFACTURER: UNKNOWN), for Covid-19 immunization; Covid-19 vaccine (DOSE: 3, MANUFACTURER: UNKNOWN), for Covid-19 immunization. The following information was reported: HOT FLUSH (disability), outcome "not recovered", described as "Hot flashes"; CHILLS (disability), outcome "not recovered". The patient underwent the following laboratory tests and procedures: Body height: 5'4, notes: She has lost some height so probably like 5'4 and like 125lbs; Weight: 125 lbs, notes: She has lost some height so probably like 5'4 and like 125lbs. Therapeutic measures were taken as a result of hot flush, chills. Clinical course: prior Vaccinations (within 4 weeks) were unknown. Patient(s) Medical History (including any illness at time of vaccination):   Provide other relevant medical history including but not limited to these conditions: diagnosed allergies, compromised immune status, respiratory illness, genetic/chromosomal abnormalities, endocrine abnormalities (including diabetes) and obesity: high blood pressure, takes high blood pressure medications, recently had a transient ischemic attack just a few weeks ago, but she has recovered the use of her right leg. Lifelong smoker. She flew to her nephew graduation last Saturday 30Apr2022 and got the vaccine before that. So, she got it either 27Apr2022 or 28Apr2022. This was her second booster. She had her initial two, then her first booster, and then this last booster. She has had little reaction at all until this point.  This is the first time she has had any reaction at all. This has persisted, and she is concerned because it has been going on more than a week.  She is pretty miserable most of the day she is in bed. All she is doing is taking NSAIDs, eating, drinking, and going to bed. Emergency Room or Physician Office was not required. List other relevant diagnostic and confirmatory test results for event(s), for example, from blood tests, cerebrospinal fluid culture, bacterial sero-type, diagnostic imaging, (e.g., chest X-ray, MRI were not reported.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: As there is limited information in the case provided, the causal association between the events and the suspect drug cannot be excluded. The case will be reassessed once new information is available.