This spontaneous case was reported by a patient and describes the occurrence of DIZZINESS (dizzy), DISORIENTATION (disoriented/He spoke in an online class and got really disoriented, had no idea of what he had said), CONFUSIONAL STATE (He would say something and be confused about it/percribing things slower), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (doesn't know if he is okay to drive) and SENSORY DISTURBANCE (feels sensory stuff in his hands /feet/ face /he is talking but he is not sure if he is making sense) in a 23-year-old male patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. AS7144B) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. Previously administered products included for Product used for unknown indication: Pfizer vaccine (Dose Number: 1, Lot number: EW0150) on 03-Apr-2021, Pfizer vaccine (Dose Number: 2 and Lot number: EW0169) on 24-Apr-2021. Past adverse reactions to the above products included No adverse event with Pfizer vaccine and Pfizer vaccine. Concurrent medical conditions included Penicillin allergy, Allergic to cats, Reactive airways disease, Asthma and HIV infection. Concomitant products included EMTRICITABINE, TENOFOVIR DISOPROXIL FUMARATE (TRUVADA) for HIV infection. On 09-Sep-2022 at 10:00 AM, the patient received fourth dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. On 10-Sep-2022, the patient experienced DIZZINESS (dizzy) and DISORIENTATION (disoriented/He spoke in an online class and got really disoriented, had no idea of what he had said). On an unknown date, the patient experienced CONFUSIONAL STATE (He would say something and be confused about it/percibing things slower), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (doesn't know if he is okay to drive), SENSORY DISTURBANCE (feels sensory stuff in his hands /feet/ face /he is talking but he is not sure if he is making sense), HYPOAESTHESIA (feels like numb), FEELING ABNORMAL (fingers in his feet feel weird) and DYSPNEA (his breathing felt a little like depressed). At the time of the report, DIZZINESS (dizzy), DISORIENTATION (disoriented/He spoke in an online class and got really disoriented, had no idea of what he had said), CONFUSIONAL STATE (He would say something and be confused about it/percibing things slower), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (doesn't know if he is okay to drive), SENSORY DISTURBANCE (feels sensory stuff in his hands /feet/ face /he is talking but he is not sure if he is making sense), HYPOAESTHESIA (feels like numb), FEELING ABNORMAL (fingers in his feet feel weird) and DYSPNEA (his breathing felt a little like depressed) had not resolved. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Oxygen saturation: 95-98 %. The patient received 2 doses of Novavax experimental vaccine on early 2021 before receiving the authorized vaccines. The patient received third dose of Moderna vaccine on 09-Dec-2021 as first booster. Lot number was 030H21B. The patient did not experience a similar event in the past. The patient did not seek any medical care. Treatment medication was not reported. This case was linked (Patient Link).