Within 8 hours of receiving 2nd booster, started to feel flu-like symptoms.; weak; every muscle in my body hurt; no appetite; tired; I slept most of the day and night; fatigued; uncomfortable; I was not able to function the following day/had to miss a day of work; This is a spontaneous report received from a non-contactable reporter(s) (Nurse). The reporter is the patient.  A 59-year-old female patient (not pregnant) received BNT162b2 (COMIRNATY), in Mar2022 as dose 4 (booster), single (Batch/Lot number: unknown) intramuscular, in left arm for covid-19 immunisation. The patient's relevant medical history included: "High cholesterol" (unspecified if ongoing); "high triglycerides" (unspecified if ongoing). Concomitant medication(s) included: LIVALO. Vaccination history included: Bnt162b2 (Dose 3), for COVID-19 immunization, reaction(s): "After the 1st Pfizer booster, I had a temp of 99 and just felt tired for a few hours the following day", "After the 1st Pfizer booster, I had a temp of 99 and just felt tired for a few hours the following day"; Bnt162b2 (Dose 2), for COVID-19 immunization, reaction(s): "After the 2nd dose of Pfizer vaccine, I had a fever of 102. for a few hours and felt general muscle aching", "After the 2nd dose of Pfizer vaccine, I had a fever of 102. for a few hours and felt general muscle aching"; Bnt162b2 (Dose 1), for COVID-19 immunization, reaction(s): "After my first Pfizer vaccine, I had a high fever of 103.3 for 5-6 hours the day following vaccination.".  The following information was reported: SOMNOLENCE (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "I slept most of the day and night"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "I was not able to function the following day/had to miss a day of work"; INFLUENZA LIKE ILLNESS (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "Within 8 hours of receiving 2nd booster, started to feel flu-like symptoms."; MYALGIA (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "every muscle in my body hurt"; FATIGUE (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "fatigued"; DECREASED APPETITE (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "no appetite"; FATIGUE (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "tired"; DISCOMFORT (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "uncomfortable"; ASTHENIA (non-serious) with onset Mar2022, outcome "recovered" (2022), described as "weak". Therapeutic measures were not taken as a result of influenza like illness, asthenia, myalgia, decreased appetite, fatigue, somnolence, fatigue, discomfort, loss of personal independence in daily activities.  Additional information: The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient received Livalo medications within 2 weeks of vaccination. Within 8 hours of receiving 2nd booster dose, started to feel flu-like symptoms.  The following morning, the patient reported that she was so weak and every muscle in her body hurt, that she had to miss a day of work and spent the day in bed. She had no appetite and was so tired, she slept most of the day and night.  When she awoke the next day, she felt better but was still fatigued for a few hours. After her first Pfizer vaccine, she had a high fever of 103.3 for 5-6 hours the day following vaccination. After the 2nd dose of Pfizer vaccine, the patient had a fever of 102. for a few hours and felt general muscle aching.  After the 1st Pfizer booster, the patient had a temp of 99 and just felt tired for a few hours the following day.  The fourth dose (2nd booster) was the most uncomfortable and she was not able to function the following day.  She did not have a fever after that dose.  She did not want to receive any further Covid vaccinations. Prior to vaccination, was the patient was not diagnosed with COVID-19. Since the vaccination, the patient had been tested for COVID-19.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.