With her 2nd dose of the COVID-19 Vaccine her rash was worse; This is a spontaneous report received from contactable reporter(s) (Nurse). The reporter is the patient.  A 50-year-old female patient received BNT162b2 (BNT162B2), on 29Mar2021 as dose 2, single (Lot number: EP6955) at the age of 50 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Asthma" (unspecified if ongoing), notes: She doesn't take her asthma medicine or her inhaler as she is afraid her heart will race. She only takes the inhaler in the morning if she needs to.; "Insomnia" (unspecified if ongoing); "Inflammatory Bowel" (unspecified if ongoing); "Supraventricular Tachycardia (SVT)" (unspecified if ongoing), notes: has had surgery twice for this; "allergic to Latex" (unspecified if ongoing); "allergic to eggs" (unspecified if ongoing); "perimenopause" (unspecified if ongoing); "Heart condition" (unspecified if ongoing), notes: She is compromised because she has asthma and a heart condition. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Dose 1, Lot number: FN6194, Anatomical Location: Left arm), administration date: 08Mar2021, when the patient was 50-year-old, for COVID-19 immunization, reaction(s): "Rash"; Flu vaccine, for Immunization, reaction(s): "allergic to the Flu Vaccine"; Mmr, for Immunization, reaction(s): "Had a reaction". The following information was reported: RASH (non-serious) with onset 2021, 2 weeks after the suspect product(s) administration, outcome "not recovered", described as "With her 2nd dose of the COVID-19 Vaccine her rash was worse". The event "with her 2nd dose of the covid-19 vaccine her rash was worse" required physician office visit. Therapeutic measures were taken as a result of rash.  Additional information: The patient did not have any family medical history relevant to adverse event. The patient didn't take her asthma medicine or her inhaler as she was afraid her heart would race. She only took the inhaler in the morning if she needs to. No additional vaccines were administered on same date of the Pfizer suspect. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. She hadn't gotten her shingles shot. As a baby she was given the MMR and had a reaction. That was how she knew she was allergic to eggs. She stated that whenever the first dose of MMR was given she had the reaction but didn't know the reaction. She was just told she couldn't eat eggs. She was allergic to the Flu vaccine as the vaccine was cultured in egg yolk. She was also allergic to Latex. Pfizer doesn't culture the vaccine in eggs. After every vaccine, the patient got a rash after 2 weeks. After 1st dose COVID-19 vaccine, she took Benadryl and the rash went away. With her 2nd dose of the COVID-19 vaccine, her rash was worse and she had to take Prednisone, which made her heart race, for 2 or 3 weeks after the injection. She didn't get a rash after her 3rd dose of the COVID-19 vaccine but she took Benadryl before she got the shot and for 7 days after to prevent a reaction. The patient received booster dose on 01Oct2021. The adverse event did not require a visit to Emergency Room. No relevant tests were done.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200856646 Same reporter, same patient, same product, different event (LOE events);US-PFIZER INC-202200856647 Same reporter, same patient, different dose, same event (Dose 1);