hand atrophy; suggest ALS; right after second vaccine severe left upper arm pain and also decreased range of motion; right after second vaccine severe left upper arm pain and also decreased range of motion; left arm and weakness/ severe weakness of left arm and hand/ weakness on left leg; frozen shoulder; trouble walking; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 70 year-old female patient (not pregnant) received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), administered in left arm, administration date 27Feb2021 (Lot number: EN6203) at the age of 70 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Asthma" (unspecified if ongoing); "GERD" (unspecified if ongoing); "allergies" (unspecified if ongoing). The patient's concomitant medications were not reported. Past drug history included: Advair, reaction(s): "Known allergies: Advair causes oral ulcers". Vaccination history included: Bnt162b2 (Dose Number: 1, Batch/Lot No: EM9809, Location of injection: Arm Left), administration date: 07Feb2021, for COVID-19 Immunization, reaction(s): "Mild left arm pain", "body aches", "fatigue", notes: mild left arm pain along with body aches fatigue after first vaccine, assumed it was just a common side effect. The following information was reported: VACCINATION SITE PAIN (disability), VACCINATION SITE MOVEMENT IMPAIRMENT (disability) all with onset 28Feb2021, outcome "not recovered" and all described as "right after second vaccine severe left upper arm pain and also decreased range of motion"; MUSCULAR WEAKNESS (disability) with onset 28Feb2021, outcome "not recovered", described as "left arm and weakness/ severe weakness of left arm and hand/ weakness on left leg"; PERIARTHRITIS (disability) with onset 28Feb2021, outcome "not recovered", described as "frozen shoulder"; GAIT DISTURBANCE (disability) with onset 28Feb2021, outcome "not recovered", described as "trouble walking"; ATROPHY (disability), outcome "unknown", described as "hand atrophy"; AMYOTROPHIC LATERAL SCLEROSIS (disability) with onset 28Feb2021, outcome "not recovered", described as "suggest ALS". The events "right after second vaccine severe left upper arm pain and also decreased range of motion", "right after second vaccine severe left upper arm pain and also decreased range of motion", "left arm and weakness/ severe weakness of left arm and hand/ weakness on left leg", "frozen shoulder", "trouble walking", "hand atrophy" and "suggest als" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: slew of tests: unknown result, notes: without clear cause of symptoms. Therapeutic measures were not taken as a result of vaccination site pain, vaccination site movement impairment, muscular weakness, gait disturbance. Therapeutic measures were taken as a result of periarthritis. Additional information: Previously relatively healthy. Right after second vaccine severe left upper arm pain that was not resolving and also decreased range of motion. Also noted left arm and weakness around this time but assumed due to left arm pain. Saw ortho, diagnosed with frozen shoulder for steroid injection. However left arm and hand weakness progressed. Saw neuro, had slew of tests done without clear cause of symptoms. Saw 2 more neurologists due to progression of symptoms. There was hand atrophy and severe weakness of left arm and hand. Also trouble walking and weakness on left leg. Other symptoms also present that suggest ALS. Not sure if vaccine caused ALS like symptoms or precipitated ALS. These resulted in: doctor or other healthcare professional office/clinic visit, disability or permanent damage. Seriousness criteria- disabling/incapacitating. No other vaccine in four weeks. No Covid prior vaccination. No Covid tested post vaccination. Bnt162b2 Dose 3 was received in the left arm on 27Sep2021 (lot number: FF2587).