felt a burning sensation on the back of his head; and a little of brain fog/brain fog/like when an elevator goes down quick/then he opened his jaw to yawn and then it's gone; fatigue; felt soreness at the injection site; feeling headaches /intermittent headaches/headaches started again first mild and then more severe but it was like sharp pain during 45 seconds; This spontaneous case was reported by a patient and describes the occurrence of FATIGUE (fatigue), VACCINATION SITE PAIN (felt soreness at the injection site), HEADACHE (feeling headaches /intermittent headaches/headaches started again first mild and then more severe but it was like sharp pain during 45 seconds), FEELING ABNORMAL (and a little of brain fog/brain fog/like when an elevator goes down quick/then he opened his jaw to yawn and then it's gone) and HEAD DISCOMFORT (felt a burning sensation on the back of his head) in a 64-year-old male patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. 060F22A) for COVID-19 prophylaxis.     No Medical History information was reported.    On 14-Oct-2022, the patient received dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. On an unknown date, the patient experienced FATIGUE (fatigue), VACCINATION SITE PAIN (felt soreness at the injection site), HEADACHE (feeling headaches /intermittent headaches/headaches started again first mild and then more severe but it was like sharp pain during 45 seconds), FEELING ABNORMAL (and a little of brain fog/brain fog/like when an elevator goes down quick/then he opened his jaw to yawn and then it's gone) and HEAD DISCOMFORT (felt a burning sensation on the back of his head). The patient was treated with IBUPROFEN (IBUPROFEN IB) for Headache, at an unspecified dose and frequency. At the time of the report, FATIGUE (fatigue), VACCINATION SITE PAIN (felt soreness at the injection site), HEADACHE (feeling headaches /intermittent headaches/headaches started again first mild and then more severe but it was like sharp pain during 45 seconds), FEELING ABNORMAL (and a little of brain fog/brain fog/like when an elevator goes down quick/then he opened his jaw to yawn and then it's gone) and HEAD DISCOMFORT (felt a burning sensation on the back of his head) was resolving.        For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were provided. Patient stated he received 1st dose of Moderna COVID-19 Vaccine on 13-Jan-2021, 2nd dose on 10-Feb-2021, 1st booster on 5-Nov-2021 and bivalent booster on 14-Oct-2022. After 1st dose patient experienced fatigue and a little of brain fog and intermittent headaches that lasted until he got his 2nd booster 1 month later. After 2nd dose and 1st booster patient did not experience any symptoms. The next day after the 2nd booster caller only felt soreness at the injection site, but 2 weeks later he started feeling headaches and he took Ibuprofen during 2 or 3 days and when he got better then suspended the treatment, but headaches started again first mild and then more severe but it was like sharp pain during 45 seconds and then stopped, and then it started again after a while during the day during another 45 seconds approximately and so on, it was not incapacitating or not requiring medical attention. Also, he felt a burning sensation on the back of his head during less than a minute and then dissipated. Another symptom was brain fog, like when an elevator goes down quick, and then he opened his jaw to yawn and then it was gone. Patient stated these symptoms were still ongoing but very subtle, headache comes and goes but not as severe as at the onset. Patient was recovering still not completely recovered.