Stress; Psoriasis; Allergy to vaccine; Fatigue extreme; REVACCINATION WITH DIFFERENT COVID-19 VACCINE; INTERCHANGE OF VACCINE PRODUCTS; Eczema flare up; Wearing off effect; Skin oozing; Blistery rash; Itchy rash; Dose 1 received on 11-APR-2021 and and dose 2 on 02-MAY-2021; This spontaneous case was reported by a consumer and describes the occurrence of ECZEMA (Eczema flare up), THERAPEUTIC RESPONSE SHORTENED (Wearing off effect), STRESS (Stress), SKIN WEEPING (Skin oozing) and PSORIASIS (Psoriasis) in a 62-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect products included non-company products TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) for COVID-19 vaccination and RISANKIZUMAB (SKYRIZI [RISANKIZUMAB]) for Plaque psoriasis.    Concurrent medical conditions included Plaque psoriasis (Moderate to severe chronic Plaque psoriasis).   On 11-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 02-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 28-Jan-2022, the patient received third dose of TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) (Intramuscular) 1 dosage form. On an unknown date, the patient started RISANKIZUMAB (SKYRIZI [RISANKIZUMAB]) (Subcutaneous) at an unspecified dose. On 02-May-2021, the patient experienced INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Dose 1 received on 11-APR-2021 and and dose 2 on 02-MAY-2021). In May 2022, the patient experienced ECZEMA (Eczema flare up) and THERAPEUTIC RESPONSE SHORTENED (Wearing off effect). In 2022, the patient experienced SKIN WEEPING (Skin oozing), RASH VESICULAR (Blistery rash) and RASH PRURITIC (Itchy rash). On an unknown date, the patient experienced STRESS (Stress), PSORIASIS (Psoriasis), ALLERGY TO VACCINE (Allergy to vaccine), FATIGUE (Fatigue extreme), COVID-19 IMMUNISATION (REVACCINATION WITH DIFFERENT COVID-19 VACCINE ) and INTERCHANGE OF VACCINE PRODUCTS (INTERCHANGE OF VACCINE PRODUCTS). In 2022, SKIN WEEPING (Skin oozing), RASH VESICULAR (Blistery rash) and RASH PRURITIC (Itchy rash) had resolved. At the time of the report, ECZEMA (Eczema flare up), THERAPEUTIC RESPONSE SHORTENED (Wearing off effect) and FATIGUE (Fatigue extreme) had not resolved, STRESS (Stress), PSORIASIS (Psoriasis), INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Dose 1 received on 11-APR-2021 and and dose 2 on 02-MAY-2021), COVID-19 IMMUNISATION (REVACCINATION WITH DIFFERENT COVID-19 VACCINE ) and INTERCHANGE OF VACCINE PRODUCTS (INTERCHANGE OF VACCINE PRODUCTS) outcome was unknown and ALLERGY TO VACCINE (Allergy to vaccine) had resolved.            No concomitant medications were provided. On unknown date in May 2022, the patient experienced Eczema flare up. Heat and stress really acts it up and started to wear off about a month before injection. The patient was injecting Skyrizi tonight. The patient was very stressed due to loss of family member. Cream was helped a little and trying to de-stress. Allergic reaction to 3rd Covid booster. The patient was broked out into a rash and not hives, more like blisters that gets from Psoriasis looking like had chicken pox. Tops of her feet, knees arms, mouth, ears. Physician tried everything and nothing helped. The patient was felt a little extra tired because she was really busy at work and did not sleep well last night. The patient saw health care professional and physician had mentioned to take time to relax and not push herself and to take probiotics. The patient was broked out into a  rash after the third Covid-19 booster. They were like blister that could squash and ooze and had an intense itch. The patient was advised not to take anymore boosters by health care professional.