Developed a rash on my torso, thighs, and chest; Fever; Headache; My joints became swollen in my knees, ankles, and hands; This is a spontaneous report from a contactable consumer (patient). A 45-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: ER8 729, Expiry date not reported), via an unspecified route of administration, administered in arm left on 01Apr2021 11:30 (age at vaccination was 45 years) as second dose, single for COVID-19 immunization. Medical history was not reported. Concomitant medication included spironolactone taken for an unspecified indication, start and stop date were not reported. Historical vaccine included bnt162b2 (Lot number: EN6208, Expiry date not reported) on 11Mar2021 13:45 at the left arm first dose, single for COVID-19 immunization. The patient was not pregnant at the time of vaccination. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient was vaccinated at a clinic. The patient was not diagnosed with COVID-19 prior to vaccination. Since the vaccination, the patient has been tested for COVID-19. The patient experienced developed a rash on torso, thighs, and chest on 21Apr2021 08:00 with outcome of recovering, fever on 21Apr2021 08:00 with outcome of recovering, headache on 21Apr2021 08:00 with outcome of recovering, and joints became swollen in my knees, ankles, and hands on 21Apr2021 08:00 with outcome of recovering. The patient underwent lab tests and procedures which included sars-cov-2 test: negative on 23Apr2021, sars-cov-2 test: negative on 25Apr2021, sars-cov-2 test: negative on 23Apr2021, and sars-cov-2 test: negative on 25Apr2021, blood test: normal on an unspecified date, and urine test: normal on an unspecified date. Therapeutic measures were taken as a result of the events that included antibiotics, Toradol, Butalb-Acetamin-Caff. The adverse events resulted in doctor or other healthcare professional office/clinic visit and emergency room/department or urgent care. The event rash was reported as serious, medically significant, while for the other events was reported as non-serious.  Narrative case summary and further information: Case Narrative: 3 weeks after the 2nd shot, I experienced a fever and headache. On day 3 from the onset of the fever, I developed a rash on my torso, thighs, and chest and my joints became swollen in my knees, ankles, and hands. My doctor told me to rest and get a COVID test. The test was negative. On the 5th day after the onset of the fever, I went to the ER as the joint pain and headache were getting worse and the rash was still not gone. The ER gave me another COVID test and a strep test, both came back negative. The ER took blood and urine samples and gave me an IV. All of the test results from blood and urine back as normal. They sent me home with antibiotics and Torodal. The next day, my headache was very severe. I went to the doctor who prescribed another headache medicine, Butalb-Acetamin-Caff, which worked to relieve the headache. The rest of that week, I rested and started to get better. After feeling better for a few days, the rash returned as is managed with Benadryl and prescribed ointment.  Follow attempts are needed. Further information is expected.