Severe nerve pain running up from injection site from Left Deltoid up the back of left should up the neck extending to the base of my head.  Pain so severe I was unable to lift or hold my head up.; Pain so severe unable to lift or hold my head up; Unable to lift or hold my head up; Unable to lift or hold my head up; Shoulder pain; Burning in cervical area; Itching in cervical area; Red spot; Life has been made a living hell; This serious case was reported by a consumer and described the occurrence of nerve pain in a 65-year-old female patient who received Herpes zoster (Shingrix) (batch number G3T43, expiry date 01-JUL-2024) for prophylaxis.   Concurrent medical conditions included hypertension and gastroesophageal reflux disease. Concomitant products included losartan and omeprazole.   On 02-MAY-2023, the patient received the 1st dose of Shingrix (left deltoid) .5 ml. On 02-MAY-2023, less than a day after receiving Shingrix, the patient experienced nerve pain (Verbatim: Severe nerve pain running up from injection site from Left Deltoid up the back of left should up the neck extending to the base of my head.  Pain so severe I was unable to lift or hold my head up.) (serious criteria clinically significant/intervention required), pain (Verbatim: Pain so severe unable to lift or hold my head up) (serious criteria clinically significant/intervention required), muscle weakness (Verbatim: Unable to lift or hold my head up) (serious criteria clinically significant/intervention required) and mobility decreased (Verbatim: Unable to lift or hold my head up) (serious criteria clinically significant/intervention required). In MAY-2023, the patient experienced shoulder pain (Verbatim: Shoulder pain), burning sensation (Verbatim: Burning in cervical area), pruritus (Verbatim: Itching in cervical area), localized erythema (Verbatim: Red spot) and impaired quality of life (Verbatim: Life has been made a living hell). The patient was treated with prednisone, gabapentin and methylprednisolone (Medrol Pak). The outcome of the nerve pain, pain, muscle weakness, mobility decreased and shoulder pain were resolving and the outcome of the burning sensation and pruritus were not resolved and the outcome of the localized erythema and impaired quality of life were not reported.   It was unknown if the reporter considered the nerve pain, pain, muscle weakness, mobility decreased, shoulder pain, burning sensation, pruritus, localized erythema and impaired quality of life to be related to Shingrix.     It was unknown if the company considered the nerve pain, pain, muscle weakness, mobility decreased, shoulder pain, burning sensation, pruritus, localized erythema and impaired quality of life to be related to Shingrix.   Additional Information: GSK Receipt Date: 27-MAY-2023 This case reported by patient for himself The reporter reported that after receiving Shingrix vaccine she had severe nerve pain running up from injection site from left deltoid up the back of left should up the neck extending to the base of head. The reporter reported that pain was so severe that she was unable to lift or hold her head up. The reporter reported that symptoms did improve after treatment of Prednisone Medrol Pak and Gabapentin 300 mg she was able to lift and hold her head up. The reporter reported that the shoulder pain had improved but there was continuous deep nerve pain, which was constantly burning and itching in cervical area, intensity varies stress brings an increase of pain with red spot but no rash. The reporter reported that symptoms appear more like ZSH (zoster sine herpete). The reporter had never experienced any of these symptoms prior to her first injection of Shingrix her physician had advised her not to take the 2nd dose. Reporter went to urgent care twice and sent to the emergency room, her life had been made a living hell after this injection. The reporter did not consent to follow up.