Nausea; severe lower back pain; fever of 102; tiredness; tingling in the fingers of both hands; numbness in the fingers of both hands; shaking uncontrollably; nightsweats; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PYREXIA (fever of 102), FATIGUE (tiredness), PARAESTHESIA (tingling in the fingers of both hands), HYPOAESTHESIA (numbness in the fingers of both hands), TREMOR (shaking uncontrollably), BACK PAIN (severe lower back pain), NIGHT SWEATS (nightsweats) and NAUSEA (Nausea) in a 27-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 048A21A and 012A21A) for COVID-19 vaccination.     No Medical history reported.  Concomitant products included ZOLPIDEM TARTRATE (AMBIEN), CLONAZEPAM and COLECALCIFEROL (VITAMIN D [COLECALCIFEROL]) for an unknown indication.   On 03-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 03-Mar-2021, the patient experienced NIGHT SWEATS (nightsweats) (seriousness criterion hospitalization). On 31-Mar-2021, the patient experienced PYREXIA (fever of 102) (seriousness criterion hospitalization), FATIGUE (tiredness) (seriousness criterion hospitalization), PARAESTHESIA (tingling in the fingers of both hands) (seriousness criterion hospitalization), HYPOAESTHESIA (numbness in the fingers of both hands) (seriousness criterion hospitalization) and TREMOR (shaking uncontrollably) (seriousness criterion hospitalization). On 01-Apr-2021, the patient experienced BACK PAIN (severe lower back pain) (seriousness criterion hospitalization) and NAUSEA (Nausea) (seriousness criterion hospitalization). The patient was hospitalized from 01-Apr-2021 to 02-Apr-2021 due to BACK PAIN, FATIGUE, HYPOAESTHESIA, NIGHT SWEATS, PARAESTHESIA, PYREXIA and TREMOR. On 02-Apr-2021, PYREXIA (fever of 102), FATIGUE (tiredness), PARAESTHESIA (tingling in the fingers of both hands), HYPOAESTHESIA (numbness in the fingers of both hands) and TREMOR (shaking uncontrollably) had resolved. At the time of the report, BACK PAIN (severe lower back pain) and NIGHT SWEATS (nightsweats) had resolved and NAUSEA (Nausea) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Body temperature: 102 f (High) 102 F.         She treated herself with acetaminophen and Ibuprofen. She went to the emergency room 01 Apr 2021, she was treated with IV fluids, anti-nausea medication. She received blood work twice and a chest x ray but results was not provided. She was discharged on 02 Apr 2021.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   This case was linked to MOD-2021-138823 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.