The valve in heart wasn't pumping to sustain oxygen level; Oxygen level dropped; left arm swollen up; breathing like crazy; couldn't walk across street; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  An 89-year-old male patient received BNT162b2 (BNT162B2), on 24Mar2021 as dose 2, single (Lot number: EN6204) at the age of 89 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Stroke" (unspecified if ongoing), notes: Stroke occurred back in the 80's.; "Heart attack" (unspecified if ongoing), notes: Heart attack occurred back in the 80's. There were no concomitant medications. Vaccination history included: BNT162b2 (Dose 1, Lot# EN6199, Route of administration: left shoulder, Dose: Assumes Adult dose was received.), administration date: 03Mar2021, when the patient was 89-year-old, for COVID-19 immunization. The following information was reported: CARDIAC VALVE DISEASE (hospitalization), outcome "not recovered", described as "The valve in heart wasn't pumping to sustain oxygen level"; OXYGEN SATURATION DECREASED (hospitalization), outcome "not recovered", described as "Oxygen level dropped"; PERIPHERAL SWELLING (non-serious), outcome "not recovered", described as "left arm swollen up"; RESPIRATION ABNORMAL (non-serious), outcome "unknown", described as "breathing like crazy"; GAIT DISTURBANCE (non-serious), outcome "unknown", described as "couldn't walk across street". The patient was hospitalized for cardiac valve disease, oxygen saturation decreased (start date: 02Jul2022, discharge date: 07Jul2022, hospitalization duration: 5 day(s)). The event "left arm swollen up" required physician office visit. The patient underwent the following laboratory tests and procedures: Oxygen saturation: Dropped; Ultrasound scan: found no blood clots. Patient was having some problems after receiving two doses Pfizer Covid Vaccine a year ago in Mar2021. Since received two doses Pfizer Covid Vaccine, left arm was swollen up. Patient has gone to doctor. The valve in heart wasn't pumping to sustain oxygen level: Has had problems with heart. Patient couldn't walk anymore. Before got Pfizer Covid Vaccine, use to walk a mile and quarter and mile and half with no problem at all. Now, patient couldn't walk across street. Patient lives in modular home and not that big, just to walk from front room to kitchen, 25 feet and do dishes and come back was breathing like crazy. Having so many problems. Patient was sent to hospital when oxygen level dropped just walking from doctor's parking lot to office, which was maybe 40 feet. Oxygen level dropped and spent five days in hospital on oxygen. Left arm swollen up happened a couple of months after receiving second dose Pfizer Covid Vaccine. It has been there ever since and was persisting. Patient went to doctor (name withheld) and a cancer doctor. Both doctors wanted to have ultrasound. Patient went to get ultrasound to see if blood clot. Found no blood clots whatsoever. Doctors don't understand why patient's arm was swollen up. The valve in heart wasn't pumping to sustain oxygen level: Asked when this began occurring and caller replies, had a heart attack a long time ago. But right now, if does anything walking or anything the valve in heart isn't pumping to sustain oxygen level. Before was dancing two and three times a week ,old time rock and the polka with no problems. Problems with heart not pumping to sustain oxygen level were persisting.