Patient reports his EENT diagnosed him with autoimmune condition called rare relapsing polychondritis.; nose swollen insanely; nose cartilage was broken; nose cartilage gets inflamed; fever; chills; This spontaneous case was reported by a consumer and describes the occurrence of POLYCHONDRITIS (Patient reports his EENT diagnosed him with autoimmune condition called rare relapsing polychondritis.) in a 27-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 0211321A and 009C21A)) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Relapsing polychondritis since 29-Apr-2021.   On 30-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 27-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 28-Apr-2021, the patient experienced PYREXIA (fever) and CHILLS (chills). On 29-Apr-2021, the patient experienced SWELLING (nose swollen insanely), CARTILAGE INJURY (nose cartilage was broken) and NASAL INFLAMMATION (nose cartilage gets inflamed). On an unknown date, the patient experienced POLYCHONDRITIS (Patient reports his EENT diagnosed him with autoimmune condition called rare relapsing polychondritis.) (seriousness criterion medically significant). The patient was treated with METHOTREXATE ongoing since an unknown date for Relapsing polychondritis, at an unspecified dose and frequency and PREDNISONE ongoing since an unknown date for Relapsing polychondritis, at an unspecified dose and frequency. At the time of the report, POLYCHONDRITIS (Patient reports his EENT diagnosed him with autoimmune condition called rare relapsing polychondritis.), PYREXIA (fever), CHILLS (chills), SWELLING (nose swollen insanely), CARTILAGE INJURY (nose cartilage was broken) and NASAL INFLAMMATION (nose cartilage gets inflamed) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication was mentioned.  Company Comment: This case concerns a 27-year-old male patient with relevant medical history of relapsing polychondritis, who experienced the unexpected serious event of Polychondritis and non-serious events of swelling, Nasal inflammation and Cartilage injury and pyrexia.The events occurred unknown days after the second dose of Spikevax. The rechallenge is not applicable since the event occurred after the second dose and no details were provided about the first dose. The benefit-risk relationship of Spikevax is not affected by this report.; Sender's Comments: This case concerns a 27-year-old male patient with relevant medical history of relapsing polychondritis, who experienced the unexpected serious event of Polychondritis and non-serious events of swelling, Nasal inflammation and Cartilage injury and pyrexia.The events occurred unknown days after the second dose of Spikevax. The rechallenge is not applicable since the event occurred after the second dose and no details were provided about the first dose. The benefit-risk relationship of Spikevax is not affected by this report.