sligthly elevated cholesterol; itchy and painful toes that turned purple; itchy and painful toes that turned purple; itchy and painful toes that turned purple/one toe on right foot turned purple; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 73-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 06Oct2022 as dose 4 (booster), single (Lot number: GH9703) at the age of 73 , in left arm for covid-19 immunisation. The patient's relevant medical history included: "Bradycardia" (unspecified if ongoing), notes: bardycardia is slow heart rate; "occasional palpitations" (unspecified if ongoing); "Little murmur" (unspecified if ongoing), notes: 30 years ago she was diagnosed with a little murmur; "mitral valve prolapse with regurgitation" (unspecified if ongoing), notes: 30 years ago diagnosed with mitral valve prolapse with regurgitation; "mitral valve prolapse with regurgitation" (unspecified if ongoing), notes: 30 years ago diagnosed with mitral valve prolapse with regurgitation; "COVID", start date: Apr2022 (unspecified if ongoing), notes: she got Covid in Apr2022. Concomitant medication(s) included: ASPIRIN 81. Vaccination history included: moderna (Dose 1; Manufacturer: Moderna LOT: 039KZOA or 039K2OA), administration date: 07Feb2021, when the patient was 72-year-old, for COVID-19 immunization; moderna (Dose 2, Manufacturer: Moderna LOT: 00ZA21A or 002A21A), administration date: 07Mar2021, when the patient was 72-year-old, for COVID-19 immunization; BNT162b2 (1st boosterDOSE 3 (BOOSTER), SINGLE; LOT: H13527, not sure about the first 2, but can clearly see 3527), administration date: 04Nov2021, when the patient was 72-year-old, for COVID-19 immunization, reaction(s): "she got Covid in Apr2022". The following information was reported: PRURITUS (non-serious), PAIN IN EXTREMITY (non-serious) all with onset 13Oct2022, outcome "recovering" and all described as "itchy and painful toes that turned purple"; BLUE TOE SYNDROME (non-serious) with onset 13Oct2022, outcome "recovering", described as "itchy and painful toes that turned purple/one toe on right foot turned purple"; BLOOD CHOLESTEROL INCREASED (non-serious), outcome "unknown", described as "slightly elevated cholesterol". The events "itchy and painful toes that turned purple", "itchy and painful toes that turned purple/one toe on right foot turned purple" and "slightly elevated cholesterol" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: The patient reported that she had 2nd booster and exactly one week later she wound up with a very itchy and painful toe. Patient didn't see it, she felt it. All her shots were given in upper left arm. She had purple toe' exactly a week after booster and the images look in online very much like what patient had. It's still not completely gone., weeks later. It was the evening of 13Oct2022, was when patient first noticed. It was one toe on right foot that then turned purple. It was still slightly discolored and more sensitive than other toes. That night when she took her sock off, her toe was changing color. It was itchy and hurt if she touched it or from the pressure of the shoe. Wearing her shoe was annoying. Patient could manage, but it hurt. Then the itching went away, but it still hurts. It still hurts now. Patient can feel it as she was talking. When she looked up toe online something that came up frequently was Covid toe. She went to see her doctor. At first doctor thought she had broken it or banged it and wanted to have x-ray. Then the doctor also saw the information and said to see what happens. Caller has photographed her toe everyday. Patient saw that this might have been an adverse event and felt it was her responsibility to report. With fears of what could happen this was minor, but it was definitely obvious that it was exactly one week after the booster to the day. Her doctor was concerned it was a blood clot and then relaxed about it and then said to see what happens. It had improved. After first booster on 04Nov2021, she got Covid in Apr2022. It was very mild case of Covid and she took Paxlovid. Then she had immunity and wanted to wait a while to get 2nd booster. Vaccination Facility Type reported as Pharmacy. Patient had no prior Vaccinations (within 4 weeks). Patient was thinking of getting flu vaccine but hasn't. Patient's doctor drew blood at that time. Patient had slightly elevated cholesterol. They want total to be 200 and patient had 210, but everything else was normal. Nothing came up with blood test to relate to her toe.