Her numbers were climbing/reported them going down after her first vaccines; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 77-year-old female patient received BNT162b2 (BNT162B2), on 29Jan2021 as dose 1, single (Lot number: EL9264) at the age of 77 years for covid-19 immunisation. The patient's relevant medical history included: "Polio", start date: 1951 (unspecified if ongoing); "5 invasive heart procedures" (not ongoing), notes: 5 invasive heart procedures; "4 strokes" (unspecified if ongoing), notes: 4 strokes; "4 different kinds of cancer" (not ongoing), notes: 4 different kinds of cancer which are hopefully all gone now depending on the latest blood results.; "Knee replacements" (not ongoing); "Myeloma" (unspecified if ongoing); "Was totally paralyzed" (unspecified if ongoing), notes: She has no residual paralysis except for the little bit she didn't recover from in the 1950s.; "Was in iron lung" (not ongoing); "Had to be revived" (not ongoing); "Lost capability to breath" (unspecified if ongoing). There were no concomitant medications. The following information was reported: THERAPEUTIC RESPONSE UNEXPECTED (non-serious) with onset 2021, outcome "unknown", described as "Her numbers were climbing/reported them going down after her first vaccines". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Patient stated that about a year and a half ago, she had an hour long conversation with a nurse from Pfizer regarding if it was possible if they were doing any clinical trials that had to do with the COVID vaccine reducing or improving cancer blood number results. She was supposed to get a call back and she never got a call. She let it go, however, she just had 2 eye shocking results with her cancer blood that pretty much takes me into normal range. The only thing that she can figure out was that she had her final booster. She called in originally because there was some kind of decline. She was wanting to see if she can now talk to someone in the area of clinical trials or research to follow-up. The numbers were significant. And she just cannot believe they would be interested. She had the 3 shots, and then she had 1 booster, and then she had the 2nd booster. If it was true if this would have an affect. Told caller no information found on the Agency regarding cancer benefits after receiving the vaccine and told caller Pfizer takes these reports very seriously. Told caller we were required to document and report any events whether positive or negative and take it very seriously in capturing these events. Offered to warm-transfer to safety to further report event. Cancer blood levels had continued to improve. This report was not related to a study or programme. She was diagnosed with Myeloma and was just in the smoldering stage. She was not to the point of being treated. They had been monitoring her since 11Sep2020. Her numbers were climbing. She reported them going down after her first vaccines. The only other thing besides the vaccine was that she had made brown goat cheese butter. She ate herself silly with that stuff. So unless that was the reason the only other thing was the Pfizer vaccine. She did not know if Pfizer had studied the vaccine in cancer blood readings. When she first called in she was interested in convalescent therapy. She wanted to know if anyone had interest in her blood. She has been through a lot of critical health issues, but she was still her alive and kicking. She had an EMG test, and the neurologist said he was surprised she was still alive. She had no residual paralysis except for the little bit she did not recover from in the 1950s. Which was very minimal. She just hopes she can help others with her information.  No follow-up attempts are possible. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101689707 same reporter/patient/vaccine, different dose/event;US-PFIZER INC-202300102500 same reporter/patient/vaccine, different dose/event;US-PFIZER INC-202300103095 same reporter/patient/vaccine, different dose (4)/similar event;