Heart rate increased; Red watery eyes; Hot flashes at night which were interfering with sleep; Nausea; Chills; Arm stiffness; Feeling blah for a day; Achy feeling; This spontaneous case was reported by an other health care professional and describes the occurrence of HEART RATE INCREASED (Heart rate increased), MUSCULOSKELETAL STIFFNESS (Arm stiffness), FEELING ABNORMAL (Feeling blah for a day), PAIN (Achy feeling) and LACRIMATION INCREASED (Red watery eyes) in a 53-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect products included non-company products MIFEPRISTONE (KORLYM) for Cushing's syndrome, SPIRONOLACTONE for an unknown indication and NIFEDIPINE for an unknown indication.    The patient's past medical history included Hysterectomy and Gallbladder removal. Concurrent medical conditions included Type 2 diabetes mellitus, Malignant hypertension, Obesity, Hypothyroidism, Cardiac septal hypertrophy, Hyperlipidemia, Adrenal adenoma (with both sides producing the same amount of cortisol (poor surgical candidate)), Depression, Anxiety, Facial hair increased, Hair loss, Cushing's syndrome and Constipation (since gall bladder removal years ago). Concomitant products included MINERALS NOS, VITAMINS NOS (CENTRUM A TO ZINC), HYDRALAZINE, LEVOTHYROXINE, METFORMIN, METOPROLOL, SENNOSIDE A+B (SENOKOT), HYDROCHLOROTHIAZIDE, VALSARTAN (VALSARTAN & HCTZ), ERGOCALCIFEROL (VIT D [ERGOCALCIFEROL]), ASA, CLONIDINE, CLONIDINE, ESTRADIOL and FUROSEMIDE for an unknown indication.   On 02-Feb-2021, the patient started MIFEPRISTONE (KORLYM) (Oral) 300 milligram once a day and SPIRONOLACTONE (unknown route) 100 milligram. On 23-Feb-2021, MIFEPRISTONE (KORLYM) (Oral) dosage was changed to 600 milligram once a day. On 25-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient started NIFEDIPINE (unknown route) 1 dosage form. On 25-Feb-2021, the patient experienced MUSCULOSKELETAL STIFFNESS (Arm stiffness), FEELING ABNORMAL (Feeling blah for a day), PAIN (Achy feeling) and CHILLS (Chills). On 21-Mar-2021, the patient experienced NAUSEA (Nausea). On an unknown date, the patient experienced HEART RATE INCREASED (Heart rate increased), LACRIMATION INCREASED (Red watery eyes) and HOT FLUSH (Hot flashes at night which were interfering with sleep). The patient was treated with LINACLOTIDE (LINZESS) at an unspecified dose and frequency; PARACETAMOL (TYLENOL) at an unspecified dose and frequency and NAPROXEN SODIUM (ALEVE) at an unspecified dose and frequency. At the time of the report, HEART RATE INCREASED (Heart rate increased), LACRIMATION INCREASED (Red watery eyes) and HOT FLUSH (Hot flashes at night which were interfering with sleep) had not resolved, MUSCULOSKELETAL STIFFNESS (Arm stiffness), PAIN (Achy feeling) and CHILLS (Chills) outcome was unknown and FEELING ABNORMAL (Feeling blah for a day) and NAUSEA (Nausea) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 15-Feb-2021, Blood pressure measurement: 108/69 (Inconclusive) 108/60 mm Hg. In March 2021, Blood pressure measurement: 153/92 (Inconclusive) 153/92 mm Hg, 152/83 (Inconclusive) 152/83 mm Hg and 160/90 (Inconclusive) 160/90 mm Hg. In March 2021, Heart rate: 69-75 (Inconclusive) 69-75 beats per minute. In March 2021, X-ray: abnormal (abnormal) Herniation at C5-C6. On an unknown date, Blood pressure measurement: 128/76 (Inconclusive) 18/76 mm Hg, 103/77 (Inconclusive) 103/77 mm Hg, 137/88 (Inconclusive) 137/88 mm Hg, 103/77 (Inconclusive) 103/77 mm Hg, 108/70 (Inconclusive) 108/70 mm Hg, 152/88 (Inconclusive) 152/88 mm Hg, 141/73 (Inconclusive) 141/73 mm Hg, 130/84 (Inconclusive) 130/84 mm Hg, 200/110 (Inconclusive) 200/110 mm Hg, 138/83 (Inconclusive) 138/83 mm Hg, 110/79 (Inconclusive) 110/79 mm Hg, 140/78 (Inconclusive) 140/78 mm Hg and 142/81 (Inconclusive) 142/81 mm Hg. On an unknown date, Heart rate: 80-90 (High) 80-90 beats per minute and 80-95 (High) 80-95 mm Hg for a week.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   The patient was treated with Claritin for red watery eyes on 28-FEB-2021 without relief. On 28-FEB-2021, blood potassium was measured whose result was not reported. On 10-MAR-2021, laboratory test everything including thyroid results were within normal limit.