Took 20 minutes to get out of bed; Hands were completely white and the nail beds were completely white.; She pressed on it and got a linear line of pink but her arms felt cold as ice; Chest discomfort; Lather up in a sweat; Chest pain; Feverish; Had a headache like a nail driving up in her brain stem; Arm was sore as a boil; Face turned beet red then became pale; Arm swole up from the top of her shoulder to the bottom of her elbow and around across to deltoid muscle; Face turned beet red; Chills in the evening time; Runny nose; This spontaneous case was reported by a consumer and describes the occurrence of RHINORRHOEA (Runny nose), PERIPHERAL SWELLING (Arm swole up from the top of her shoulder to the bottom of her elbow and around across to deltoid muscle), ERYTHEMA (Face turned beet red), ASTHENIA (Took 20 minutes to get out of bed) and PALLOR (Face turned beet red then became pale) in a 69-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 058E21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Atypical angina (She has a history of atypical angina (20 years ago) with coronary vasospasm.) in 2001, Clot blood (She does have a history of blood clots with ischemic bowel.), Bowel ischemia and Norovirus infection in June 2021. Concomitant products included METOPROLOL for Heart rate abnormal.    On 11-Sep-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 11-Sep-2021, the patient experienced RHINORRHOEA (Runny nose) and CHILLS (Chills in the evening time). On 12-Sep-2021, the patient experienced PERIPHERAL SWELLING (Arm swole up from the top of her shoulder to the bottom of her elbow and around across to deltoid muscle) and PAIN IN EXTREMITY (Arm was sore as a boil). 12-Sep-2021, the patient experienced ERYTHEMA (Face turned beet red), PALLOR (Face turned beet red then became pale) and HEADACHE (Had a headache like a nail driving up in her brain stem). 12-Sep-2021, the patient experienced PYREXIA (Feverish). On 13-Sep-2021, the patient experienced ASTHENIA (Took 20 minutes to get out of bed), NAIL DISCOLOURATION (Hands were completely white and the nail beds were completely white.), PERIPHERAL COLDNESS (She pressed on it and got a linear line of pink but her arms felt cold as ice), CHEST DISCOMFORT (Chest discomfort) and HYPERHIDROSIS (Lather up in a sweat). 13-Sep-2021, the patient experienced CHEST PAIN (Chest pain). The patient was treated with IBUPROFEN (ADVIL [IBUPROFEN]) on 13-Sep-2021 for Adverse event, at an unspecified dose and frequency. At the time of the report, RHINORRHOEA (Runny nose), PERIPHERAL SWELLING (Arm swole up from the top of her shoulder to the bottom of her elbow and around across to deltoid muscle), ERYTHEMA (Face turned beet red), ASTHENIA (Took 20 minutes to get out of bed), PALLOR (Face turned beet red then became pale), NAIL DISCOLOURATION (Hands were completely white and the nail beds were completely white.), PERIPHERAL COLDNESS (She pressed on it and got a linear line of pink but her arms felt cold as ice), CHEST DISCOMFORT (Chest discomfort), HYPERHIDROSIS (Lather up in a sweat), PAIN IN EXTREMITY (Arm was sore as a boil), CHEST PAIN (Chest pain), PYREXIA (Feverish), HEADACHE (Had a headache like a nail driving up in her brain stem) and CHILLS (Chills in the evening time) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In June 2021, SARS-CoV-2 test negative: negative (Negative) Negative.         Patient heart rate sometimes goes up to 165, but was found to be 75 at the time of reporting.   This case was linked to MOD-2021-321068.