irritation at covid Vaccination site; Fatigue; Chronic obstructive pulmonary disease; motor vehicle accident; Back pain; received 3rd dose covid-19 vaccine; received 3rd dose covid-19 vaccine; artery in one leg was pinched; cracked vertebrae; This is a solicited report from a program based on information received by Pfizer from AbbVie, (MFR Control No. 21K-163-4109576-00). A contactable 59-year male consumer (patient) reported for himself that:  Solicited report by a consumer of a 59 year old male with events of artery in one leg was pinched and non-serious irritation at covid vaccination site, cracked vertebrae, fatigue, chronic obstructive pulmonary disease, motor vehicle accident and back pain with Humira (adalimumab). there was no reported medical history. On unknown dates, the patient experienced irritation at covid vaccination site, fatigue and chronic obstructive pulmonary disease. In 2021, the patient experienced artery in one leg was pinched, cracked vertebrae and back pain. on 11May2021, the patient experienced motor vehicle accident. on unknown dates, irritation at covid vaccination site and fatigue resolved. Pfizer BioNTech covid-19 vaccine (tozinameran) was also considered suspect. On 11May2021, the patient had motor vehicle accident and an artery was pinched and had undergone surgery to place stent in that artery. he also had cracked vertebrae in the accident and had back pain. he had chronic obstructive pulmonary disease. he had irritation and fatigue after third dose of Pfizer vaccination. it was unknown if patient was enrolled in a covid-19 vaccine trial. on unknown date, patient received 1st dose covid-19 vaccine manufactured by Pfizer. on unknown date, patient received 2nd dose covid-19 vaccine manufactured by Pfizer. on unknown date, patient received 3rd dose covid-19 vaccine manufactured by Pfizer. Primary reporter did not have the lot number information, because the information was not accessible to the physician at his/her clinical setting.   Causality for Humira (adalimumab): The reporter's causality for the event(s) of artery in one leg was pinched, irritation at covid vaccination site, cracked vertebrae, fatigue and back pain with Humira (adalimumab) was no reasonable possibility. the reporter's causality for the event(s) of chronic obstructive pulmonary disease and motor vehicle accident was not provided. AbbVie's opinion is that there is no reasonable possibility that the events of artery in one leg was pinched, irritation at covid vaccination site, cracked vertebrae, fatigue, chronic obstructive pulmonary disease, motor vehicle accident and back pain are related to Humira (adalimumab).  The reporter's assessment of the causal relationship of the events with the suspect product was not provided at the time of this report. Since no determination has been received, the case is managed based on the company causality assessment  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Based on the information provided by the reporter, it appears unlikely that subject vaccine contributed to the events of artery in one leg was pinched and cracked vertebrae.