fever; High BP; headache; This is a spontaneous report from a non-contactable consumer (patient). This 64-year-old female patient received her first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot number: ER7030) via an unspecified route of administration on 24Mar2021 17:00 on Arm Left as single dose for COVID-19 immunisation. The patient medical history was not reported. Concomitant medication included lisinopril dihydrate (LISINOPRIL). On 24Mar2021 02:00, after receiving her first shot, that 1st night, she had a little bit of headache, and then she was fine, and high blood pressure (BP)/ blood pressure went up. On 25Mar2021, the second day, she had fever. Her fever was 101.2 degrees Fahrenheit and lasted a few hours. She ended up going to the doctor and they walked her to the Emergency Room and was treated. She had additional heart tests scheduled with a cardiologist. She had Covid-19 in Nov2020 which showed sars-cov-2 test positive and had antibodies present when drawn during BP episode and they were 214/101. She had an antibody test with her doctor. She has the results from the antibody test. She asked if there was a certain antibody number that would say she did not need the second dose. She enquired if she should wait to get her second vaccine dose and if it was needed to repeat both doses. She went to town for a new blood pressure cuff because with her old cuff, her blood pressure was going over 200. Her husband suggested there could be something wrong. She checked it the next morning, 25Mar2021, and it was still high. She called and went to the doctor. The doctor did an EKG and then walked her to the Emergency Department where she had a blood pressure of 214/101. Now, she has to go have a stress tests and heart tests scheduled for next week, the 29th. Her blood pressure was better the next day after being seen in the ER, clarified as 26Mar2021. She was prescribed Lisinopril 5mg, by mouth, once a day for her blood pressure in the ER and started taking from 25Mar2021. She is continuing to take this medication. She has to go to an appointment and has to continue monitoring her blood pressure. Her blood pressure is still up. She clarifies it is not as high as it was, but her blood pressure being high is still continuing. She is scheduled for her appointment for a NUC medical test, which has to do with her heart. There is a stress test with part of it which is scheduled for next Thursday. Then, once she is done with the first part, they schedule the second part where they will take pictures of her heart. The event blood pressure went up required a visit to Emergency Room and Physician Office. Outcome of blood pressure went up was not recovered. The patient was recovered from headache on 24Mar2021, and recovered from fever on 25Mar2021. The caller is scheduled for her second dose of the Covid-19 shot today at 14;00 central time. She had been trying to get a hold of someone. Of course, she is concerned about getting her second shot, if she should or not? She is concerned with getting the second dose after what happened the first time. The consumer considered the events as non-serious.   No follow-up attempts are needed; information about lot/batch number cannot be obtained.  Follow-up (21Apr2021): New information from a contactable consumer included: patient age, event information, lab data, lot#/location/time of BNT162B2. The case was upgraded to serious.   No follow-up attempts are needed. No further information is expected.