tiredness; headache; muscle pain; chills; fever; nausea; decreased appetite; could not eat anything; I really did not feel well at all; Body aches; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 70 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in arm left, administration date 01Nov2021 (Lot number: FF2589) at the age of 70 years as dose 3 (booster), single for covid-19 immunisation; influenza vaccine inact split 3v (FLUZONE HIGH DOSE), administered in arm left, administration date 11Oct2021 (Batch/Lot number: unknown) as high dose quad 2021-22. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose: 1, Date / Time, Date (dd-Mmm-yyyy): 06Apr2021, Time(24hr): 08:00am, Site and Route of injection, Anatomical Site of injection: Left Arm, Route of administration: Intramuscular, Batch/Lot number: EP7533), administration date: 06Apr2021, when the patient was 70 years old, for COVID-19 Immunization; Bnt162b2 (Dose: 2, Date / Time, Date (dd-Mmm-yyyy): 27Apr2021, Time(24hr): 11:10am, Site and Route of injection, Anatomical Site of injection: Left Arm, Route of administration: Intramuscular, Batch/Lot number: EW0171), administration date: 27Apr2021, when the patient was 70 years old, for COVID-19 Immunization. The following information was reported: FATIGUE (non-serious) with onset 01Nov2021, outcome "unknown", described as "tiredness"; HEADACHE (non-serious) with onset 01Nov2021, outcome "unknown", described as "headache"; MYALGIA (non-serious) with onset 01Nov2021, outcome "unknown", described as "muscle pain"; CHILLS (non-serious) with onset 01Nov2021, outcome "unknown", described as "chills"; PYREXIA (non-serious) with onset 01Nov2021, outcome "recovering", described as "fever"; NAUSEA (non-serious) with onset 01Nov2021, outcome "unknown", described as "nausea"; DECREASED APPETITE (non-serious) with onset 01Nov2021, outcome "unknown", described as "decreased appetite"; EATING DISORDER (non-serious) with onset Nov2021, outcome "unknown", described as "could not eat anything"; MALAISE (non-serious) with onset Nov2021, outcome "unknown", described as "I really did not feel well at all"; PAIN (non-serious) with onset Nov2021, outcome "unknown", described as "Body aches". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of pyrexia, pain.  Additional information: Approximately twelve hours after receiving the booster shot for Pfizer in the Monday morning and by late Monday night (at 2:00 am) experienced tiredness headache muscle pain chills fever (101 degree), nausea and decreased appetite. Felt fine right after the shot but then about 12 hours later, started experiencing a number of symptoms, had a fever, headache, muscle pain, chills, nausea. could not eat anything. Patient really did not feel well at all and I did not have any reaction with the first two shots. So was a little surprised and really did not feel well at all and did not have any reaction with the first two shots, so was a little surprised but was really was down for the count there for about all night and into the morning into Tuesday morning. Patient took some Advil and that helped with the body ache and fever, Ibuprofen tablets, 200mg and took 2 tablets and then about 12 hours later, took 2 more tablets that helped out to made feel little better No follow-up attempts are possible. No further information is expected.