My heart rate shot up to 150 bpm after 5 minutes; elevated my blood pressure; most severe heart burn; rash; numbness; tingling; anxiety and am very short tempered; irritable; heartrate stayed elevated; very short tempered; body temperature: 104 fahrenheit; This is a spontaneous report from a contactable consumer (patient). A 49-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot number was not reported) via an unspecified route of administration on an unspecified date as dose 1, single for COVID-19 immunisation. Medical history included Lupus and Sjogren's from an unknown date and unknown if ongoing. The patient's concomitant medications were not reported. The patient previously took pneumococcal vaccine and experienced fever, tetanus vaccine and experienced fever, benlysta, methotrexate. Patient had bad reaction after getting the 1st dose of the COVID vaccine. Two weeks later, patient still having issues. Had a reaction within 5 minutes of getting it. Patient heart rate shot up to 150 bpm after 5 minutes, which elevated patient blood pressure and patient had the most severe heart burn. Patient also had the rash and numbness and tingling and took a Benadryl. Patient had the normal reactions that continued going on for a week until it subsided. Patient noticed as he progressed going into the 2nd week, Patient developed anxiety and very short tempered, mean, and irritable. she never had any of that before. There was another drug that she took for lipids and the reaction is verily similar. she is due for 2nd dose next weekend. The only reason they made them stay was because her blood pressure and heartrate stayed elevated. She has never had a reaction to a drug or anything like this but she is sensitive to vaccines. She got the pneumonia vaccine shot and had a 104 degree fever for a week, was sick for a week but that went away. She had to get tetanus vaccine shot and had the same reaction as she did with the pneumonia vaccine. She already called manufacturer for Benlysta which is an IV lupus drug which years ago she had to get off of because of the reaction. A week into it the accelerated heart rate, elevated blood pressure, all that went away, she was good to go. What hasn't gone away, unknown it was a mixture, if it messes with hormones, but it was doing the same as the Benlysta: she has been mean, short tempered, irritable and had anxiety and those was not common with her at all. She asked manufacturer for Benlysta and wanted to see if Pfizer will email her the ingredients in the Pfizer COVID-19 Vaccine so that when she goes to see the doctor she can prepare and see if there are any similarities of the Pfizer COVID-19 Vaccine to Benlysta that is making this happen. From last week the doctor said she knows with taking Methotrexate if she only sticks with the one dose of the Pfizer COVID-19 Vaccine that instead of like the 80% protection she is going to fall down to like 70% protected from COVID-19; and if she got the second dose of Pfizer COVID-19 Vaccine instead of the like 95% protected she will be like in the mid to high 80s which she prefers over getting COVID-19. The patient underwent lab tests and procedures which included body temperature: 104 fahrenheit on an unspecified date, heart rate: 150 on an unspecified date. Therapeutic measures were taken as a result of rash, numbness, tingling. Outcome of all the events were unknown.  No follow-up attempts are possible; information about lot/batch number cannot be obtained.