she got a big hive on her body that started on her shoulders and popped up on different spots of her body; Some spots hurt more than others.  I got it on my tongue and woke up with my tongue swollen; left ankle was hurting her and swollen/left shoulder was hurting really bad; left ankle was hurting her and swollen/swelled up again on her left shoulder; her whole throat was swollen, itchy; knee like on her bone, it's really hard; she took some Benadryl, thought it was an allergic reaction to the shot; her bone was hurting, her whole left arm was hurting to the core of her bone; This is a spontaneous report from a contactable consumer (patient).  A 38-year-old female patient received bnt162b2 (BNT162B2), dose 2 via an unspecified route of administration, administered in Arm Left on 13May2021 10:30 (Batch/Lot Number: ER2613); dose 1 administered in Arm Left on 23Apr2021 (Batch/Lot Number: EW0172) as single dose for covid-19 immunisation at the age of 38-year-old.  Medical history included ongoing hypertension from the summer of 2019 but she didn't really start taking any medication for it until the summer of 2020. Concomitant medication included losartan taken for hypertension from 2020 and ongoing. About three days after the second dose (also reported on 16May2021), she got a big hive on her body that started on her shoulders and popped up on different spots of her body. It went away after a week and then came back.  She has had it for the last week and its coming up on different spots. It itches and it hurts. They were big bumps that are moving. They itch, their hot and they do hurt.  Some spots hurt more than others.  I got it on my tongue and woke up with my tongue swollen.  I got one on my face, neck, back, shoulders, arms. I would say this is severe but I'm still breathing.  Reporter stated she got the Pfizer vaccine and she got the first and second dose and about 3 days after she got the second dose, she got a big hive on her body. Reporter stated it started on her shoulders and kind of like spread, it popped up in different spots and stayed for about a week and then it went away so she wasn't worried. Reporter stated she took some Benadryl, thought it was an allergic reaction to the shot and then all of a sudden a month, almost 2 months now, came back and won't go away. Reporter stated she's had it about a week again, its been popping up in different spots since the shot, it's moved down her body and its really hard, it itches, it hurts in certain spots where it goes, then it moves and its not going away now. stated she knows its the shot because she's never been allergic to medicine in her life and never had a allergic reaction like this. Reporter stated she's assuming it went away. Reporter stated on her ankle, it had swollen up and she had a physical and the doctor checked her ankle and said it didn't look like anything was wrong, she didn't sprain it, she wasn't sure why it was hurting. Reporter stated they did an x-ray and everything was fine, it didn't show any problems with ligaments or bones. Reporter stated she doesn't know if it settled there for a while, her left ankle was hurting her and swollen, she doesn't know why it was swollen. Reporter stated she had that for about 2 weeks, actually it still comes and goes, but its gone right now, actually it was more than 2 weeks. Reporter stated these hives haven't been completely gone, they weren't as much. Reporter stated like right now its all over her body, all over her back, the back of her legs, its like right under the skin and it still gets in the muscle or something, the knee like on her bone, its hard in one spot. Reporter stated it just keeps moving spots in her body and its so weird because on her left ankle it was really sore and hurting her and then it went up to her left shoulder and her left shoulder was hurting her for a while but she didn't have a bump, and then all of a sudden the left shoulder was hurting her really bad, every night she couldn't sleep on it. Reporter stated all of a sudden she swelled up again on her left shoulder. Reporter stated it looks like there's a baseball in her shoulder. Reporter stated at first she thought it was a bug bite, but bug bites don't move. Reporter stated it started small, like a small bump and it got bigger and bigger and bigger at least 2 inches wide, like a deformed circle, not even a regular circle and it got really big on her shoulder, so big that it looked like there was a baseball in her shoulder. Reporter stated it was really red, really hard, really hot, super hard, and itchy and then it moved. Reporter stated this pain, its so weird, this pain on her left shoulder, she's a little worried about it and then she took some pain killers and so one night when all these bumps started coming back, her left shoulder it was hurting her so bad, her whole bone, her whole left arm was hurting to the core of her bone. Reporter stated her hands and palms got swollen and it hurt so bad she was crying. Reporter stated they were not home, so she didn't want to go to the doctors over there. Reporter stated she doesn't want to go to the doctor because she's scared they are going to keep her in a room for observation and not let her out because they don't know what the hell to do so that's the only reason she hasn't gone to the doctor. Reporter stated another night she woke up and her esophagus, or the little thing in the back of her throat, that thing was swollen, her whole throat was swollen and itchy and that went away in 24 hours. Reporter stated she keeps swelling up in different spots in her body and then it moves. Reporter stated her arm, its one spot in her arm, its really hard. Reporter stated when it got into her palms, it got really red looked like bruises then went away. Reporter stated now, it's all over her back now, all kinds of bumps, all over her back from one side to the other. Reporter stated this is really freaking her out. Reporter stated and right now its behind her knees, so it never really has gone away, it's just gone in different spots. Reporter stated it wasn't as bad, then all of a sudden, its all over her body so it never really went away. Reporter stated it's like everyday its getting worse. Reporter stated she's got bumps all over the back of her neck that's going up into her scalp now. Reporter stated if she saw them, she would think they were hives. Reporter stated all her symptoms began in May after she got the COVID shot and then after the COVID shot, they stayed for a little while then they spread through her body in a whole week then moved in all different parts of her  body, her inner thighs, ankle, right shoulder, then it kind of went away in her body, but she still felt pain on right shoulder on the inside and her left ankle was swollen then all of a sudden it popped up all over body again. Reporter stated it started happening in the last week and its crazy, its all over. Reporter stated she thought it was gone, but now that it came back, she knows that pain in her right shoulder was from it, she means her left shoulder. Reporter stated it doesn't pain her anymore but like she said her whole arm got swollen, her palms got swollen and it moved from that spot. Reporter stated and she knows she got the x-ray after she got the shot because she had a physical and the doctor wanted to update other shots, ones she gets as she gets older and the caller told the doctor that she's getting these bumps, its really weird, she's not sure where they are from, and so the doctor didn't give her any shots and told her she was having a reaction from the Pfizer. Reporter stated the doctor didn't say she knew what to do or anything. Reporter stated all the big bumps she's getting again had went away so she wasn't concerned anymore because she thought the reaction was already done but really it wasn't because that's why her left shoulder is hurting her and ankle is bothering her and she knows its from the shot because the bump on the ankle went away and she didn't even do anything to her ankle , she didn't twist it or anything and the same thing happened to her left shoulder. Reporter stated all the bumps are really freaking her out because they aren't going away, but now they are all over her body again. The patient underwent lab tests and procedures which included x-ray: didn't show any problems in May2021. The outcome of the events was unknown. The patient didn't visit Emergency Room or Physician Office.  Follow-up attempts are completed. No further information is expected.