had pain in the upper left arm,woke up in so much pain under the arm at the same side as the shot,had pain in the upper left armas 8 out 10 on a pain scalenow the pain is 3 out of 10 under the arm,pain under the arm came back; described it as burning hot marble underneath the skin.; woke up in the middle of night in most excruciating pain; was feverish,fever on Saturday,101 degrees Fahrenheit; bad headache,head was hurting so bad; This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (had pain in the upper left arm,woke up in so much pain under the arm at the same side as the shot,had pain in the upper left armas 8 out 10 on a pain scalenow the pain is 3 out of 10 under the arm,pain under the arm came back), BURNING SENSATION (described it as burning hot marble underneath the skin.), PAIN (woke up in the middle of night in most excruciating pain), PYREXIA (was feverish,fever on Saturday,101 degrees Fahrenheit) and HEADACHE (bad headache,head was hurting so bad) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014F21A, 024M20A and 029A21A) for COVID-19 vaccination.     No medical history was provided by the reporter.  Concomitant products included LISINOPRIL DIHYDRATE (LISINOPRIL [LISINOPRIL DIHYDRATE]) and METOPROLOL TARTRATE (METOPROLOL [METOPROLOL TARTRATE]) for an unknown indication.   On 09-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 10-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 10-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 11-Dec-2021, the patient experienced PAIN IN EXTREMITY (had pain in the upper left arm,woke up in so much pain under the arm at the same side as the shot,had pain in the upper left armas 8 out 10 on a pain scalenow the pain is 3 out of 10 under the arm,pain under the arm came back), BURNING SENSATION (described it as burning hot marble underneath the skin.), PAIN (woke up in the middle of night in most excruciating pain), PYREXIA (was feverish,fever on Saturday,101 degrees Fahrenheit) and HEADACHE (bad headache,head was hurting so bad). The patient was treated with IBUPROFEN (ADVIL [IBUPROFEN]) for Adverse event, at a dose of 3 doses. On 11-Dec-2021, HEADACHE (bad headache,head was hurting so bad) had resolved. At the time of the report, PAIN IN EXTREMITY (had pain in the upper left arm,woke up in so much pain under the arm at the same side as the shot,had pain in the upper left armas 8 out 10 on a pain scalenow the pain is 3 out of 10 under the arm,pain under the arm came back) had not resolved and BURNING SENSATION (described it as burning hot marble underneath the skin.), PAIN (woke up in the middle of night in most excruciating pain) and PYREXIA (was feverish,fever on Saturday,101 degrees Fahrenheit) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 11-Dec-2021, Body temperature: 101 (High) fever of 101 degrees Fahrenheit.         The patient reported that after her most recent dose, woke up in the middle of night in most excruciating pain, was feverish, had such a bad headache, and pain in the upper left arm. The patient woke up in so much pain under the arm at the same side as the shot and described the pain as 8 out 10 on a pain scale. The patient stated that her head was hurting so bad and now the pain is 3 out of 10 under the arm. The patient was having fever on Saturday, 11-Dec-2021 and it was 101 degrees Fahrenheit and went steadily down that day. After a dose of Advil, the headache and pain under the arm subsided but 12 hours after taking the Advil, the pain under the arm came back but not the headache. The patient stated that she can point to where the pain is and described it as burning hot marble underneath the skin.