septic shock; Cardiogenic Shock; This literature-study case was reported in a literature article and describes the occurrence of SEPTIC SHOCK (septic shock) and CARDIOGENIC SHOCK (Cardiogenic Shock) in a 75-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.      Concurrent medical conditions included Hypertension, Congestive heart failure, Coronary artery disease, Chronic obstructive lung disease and Type 2 diabetes mellitus.   On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to at an unspecified dose. On an unknown date, the patient experienced SEPTIC SHOCK (septic shock) (seriousness criteria death, hospitalization and medically significant) and CARDIOGENIC SHOCK (Cardiogenic Shock) (seriousness criteria death, hospitalization and medically significant). The reported cause of death was Septic shock and Cardiogenic shock. It is unknown if an autopsy was performed. Possible      The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) and mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown Route) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered SEPTIC SHOCK (septic shock) and CARDIOGENIC SHOCK (Cardiogenic Shock) to be possibly related.    Concomitant product and treatment medication use was not provided by the reporter.  Company Comment: This case concerns a 75-year-old female patient, with medical history of Hypertension, Congestive heart failure, Coronary artery disease, Chronic obstructive lung disease and Type 2 diabetes mellitus, who experienced the unexpected, serious fatal events of SEPTIC SHOCK and CARDIOGENIC SHOCK. The events occurred during the 10 following days after the administration a dose of Moderna COVID-19 Vaccine. The reported cause of death was SEPTIC SHOCK and CARDIOGENIC SHOCK. The rechallenge was not applicable. Patient´s medical history of Hypertension, Congestive heart failure, Coronary artery disease, Chronic obstructive lung disease and Type 2 diabetes mellitus, remain as confounders. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.   This case was linked to MOD-2021-371501, MOD-2021-371538, MOD-2021-371539, MOD-2021-371540, MOD-2021-371541, MOD-2021-371542, MOD-2021-371543 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 03-Nov-2021: Follow up received by safety 03-Nov-2021 included an Email received from a regulatory authority and  contains significant information. Added correspondence contact in general tab, medical relevant history in patient tab.; Sender's Comments: This case concerns a 75-year-old female patient, with medical history of Hypertension, Congestive heart failure, Coronary artery disease, Chronic obstructive lung disease and Type 2 diabetes mellitus, who experienced the unexpected, serious fatal events of SEPTIC SHOCK and CARDIOGENIC SHOCK. The events occurred during the 10 following days after the administration a dose of Moderna COVID-19 Vaccine. The reported cause of death was SEPTIC SHOCK and CARDIOGENIC SHOCK. The rechallenge was not applicable. Patient´s medical history of Hypertension, Congestive heart failure, Coronary artery disease, Chronic obstructive lung disease and Type 2 diabetes mellitus, remain as confounders. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.; Reported Cause(s) of Death: Septic Shock; Cardiogenic Shock