Patient got Charley horse on left calf.; Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose; Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose; Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose; Patient started feeling week and fatigue in the evening after receiving 2nd dose; Patient started feeling week and fatigue in the evening after receiving 2nd dose; Patient feels discomfort more on lower extremities as of now; This spontaneous case was reported by a consumer and describes the occurrence of ASTHENIA (Patient started feeling week and fatigue in the evening after receiving 2nd dose), FATIGUE (Patient started feeling week and fatigue in the evening after receiving 2nd dose), HEADACHE (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose), ARTHRALGIA (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose) and BACK PAIN (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose) in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013A21A and 012M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included METOPROLOL and COLECALCIFEROL (VIT D [COLECALCIFEROL]) for an unknown indication.   On 01-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage form. On 01-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 ml. On 05-Mar-1903, the patient experienced LIMB DISCOMFORT (Patient feels discomfort more on lower extremities as of now). On 01-Mar-2021, the patient experienced ASTHENIA (Patient started feeling week and fatigue in the evening after receiving 2nd dose) and FATIGUE (Patient started feeling week and fatigue in the evening after receiving 2nd dose). On 02-Mar-2021, the patient experienced HEADACHE (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose), ARTHRALGIA (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose) and BACK PAIN (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose). On 04-Mar-2021, the patient experienced PAIN IN EXTREMITY (Patient got Charley horse on left calf.). The patient was treated with PARACETAMOL (TYLENOL) for Adverse event, at a dose of UNK dosage form. At the time of the report, ASTHENIA (Patient started feeling week and fatigue in the evening after receiving 2nd dose), FATIGUE (Patient started feeling week and fatigue in the evening after receiving 2nd dose), HEADACHE (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose), ARTHRALGIA (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose), BACK PAIN (Patient started headache and severe joint pain(hips and back) next day after receiving 2nd dose), PAIN IN EXTREMITY (Patient got Charley horse on left calf.) and LIMB DISCOMFORT (Patient feels discomfort more on lower extremities as of now) outcome was unknown.            Other concomitant medication included Vitamin B, not otherwise specified.   This case was linked to MOD-2021-036757 (Patient Link).