changes in skin color/darkening and lightening of skin next to private parts, back, arms; thickening of skin; peeling of skin; skin has started to become leathery and heavy; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 74 year-old male patient received bnt162b2 (BNT162B2), administration date 30Aug2021 (Lot number: EW0179) as dose 3 (booster), single for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose 1, Single, Lot number- EN6208), administration date: 19Mar2021, for COVID-19 immunization; Bnt162b2 (Dose 2, Single, Lot number- EP7533), administration date: 08Apr2021, for COVID-19 immunization. The following information was reported: SKIN DISCOLOURATION (non-serious) with onset 2021, outcome "not recovered", described as "changes in skin color/darkening and lightening of skin next to private parts, back, arms"; SKIN HYPERTROPHY (non-serious) with onset 2021, outcome "not recovered", described as "thickening of skin"; SKIN EXFOLIATION (non-serious) with onset 2021, outcome "not recovered", described as "peeling of skin"; SKIN DISORDER (non-serious) with onset 2021, outcome "not recovered", described as "skin has started to become leathery and heavy". The events "changes in skin color/darkening and lightening of skin next to private parts, back, arms", "thickening of skin", "peeling of skin" and "skin has started to become leathery and heavy" were evaluated at the physician office visit. Therapeutic measures were taken as a result of skin discolouration, skin hypertrophy, skin exfoliation, skin disorder. Additional information: Patient and his wife received the booster dose from COVID-19 vaccine. They noticed changes in skin color, thickening of skin, peeling of skin, darkening and lightening of skin next to private parts, back, arms. He was 74 and his wife was 68 years old. Their son who received the Moderna vaccine did not have any symptoms. Patient had went to a doctor and a dermatologist and received no solution. He wanted to know if these were normal side effects. He wanted to know if different DNA types present different side effects. He had skin peeling and his doctor said there is nothing wrong with the vaccine. His son was a doctor and said he needed a special cream, but patient doctor does not know anything about it and he does not understand how one doctor knows and his does not. He said there are a lot of people that make complaints about it.  He wants to know how far did Pfizer go to research this. He said it happened to him and his wife. His skin was peeling very badly, especially in his private parts, around it and in the middle.  His skin is different color, and is dark and light.  It is like leather and not smooth like it used to be and discolored dark and light.  Next to private, it peels. He wanted to know if there has been any research about skin peeling. He did not have any specific people to report for that had the same problem. When probed for the product name, he stated that he took the third shot booster in Apr2021, since then his skin had started to become leathery and heavy. His skin was becoming thick and it's changing in color, like getting darker, it's also starting to peel, but part of it is light. The worst thing is that it's starting to peel, it's becoming in which the skin is just coming out next to the private parts and next to the penis. He used a heavy loofah to get rid of it, but it was just coming again and again, it was very bad. He confirmed he was calling about the Pfizer Covid Vaccine. He was again probed for his vaccine dates, he states that it did not happen from the first or second dose, it happened after the booster. He confirmed his booster was not in Apr2021 after looking at the covid vaccine card. As per patient the skin itself was not smooth like it used it be it was rough, it was coarse. It was 2 different color one dark and one light. The patches were light. The most bad part he peel next to the private and on the private. The private was light but the skin next to is black. He peel quarter to half an inch pieces. It was a lot every time he went to the bathroom. He washed it with very heavy D3. It was very hard; was day the same problem. Cortisone cream did not help. Now his skin started to peel, the skin coming out next to the private and on the private itself. It was full of dead skin, the color was dark. He was light tan, the peeled skin was dark/black.   No follow-up attempts are possible. No further information is expected.  Follow-Up (24Jan2022): Follow-up attempts are completed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200114126 same reporter/product/event, different patient.