blood pressure systolically reached 170/Blood pressure shot up; blood pressure systolically reached 170/Blood pressure shot up; Felt like someone was choking her; Felt like her jaw was swelling/felt like her jaw was "getting large"; Extreme weakness; Couldn't stand; This is a spontaneous report from a contactable consumer via Medical information team. An 86-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE), dose 1 via an unspecified route of administration, administered in Arm Left on 25Mar2021 16:30 (Batch/Lot number was not reported) as SINGLE DOSE for COVID-19 immunization. Medical history included ongoing multiple sclerosis , ongoing hypertension, ongoing diabetes mellitus, myocardial infarction from an unknown date and unknown if ongoing stent placed and spasms; and from an unknown date and unknown if ongoing. The patient previously had flu shot and feel a little bit sick, it hit her lot harder with the flu shot. Concomitant medication includes, unspecified, diabetic and hypertensive medication and medication for spasms. On 25Mar2021, 45 minutes to an hour after the patient's first dose, the patient felt like someone was choking her and felt like her jaw was "getting large" without physically getting large. The patient was not able to get out of her wheelchair, even though she was normally able to do so on her own, and her blood pressure systolically reached 170. Her mother was given "excess water" and was given her hypertensive medication "a little early" which caused her pressure to come down quickly. Based on this reaction that her mother had, caller would like to know if it was safe for the patient to receive her second dose of the vaccine. They stayed about 15 min at the drive thru to make sure there was no reaction. It was about a 30-minute drive home with traffic. It happened within the hour, right when she got in the house. The patient had a reaction to the first dose, and the caller wanted to know if it was safe for her to get the second. Within the first hour the patient felt like someone was choking her, she felt like her jaw was swelling, she felt extreme weakness and could not stand, and her blood pressure shot up. It shot up to 170, but she did not know the diastolic. The patient felt like she was choking so she was doused with water to push anything through in case that would help. Within a couple of hours, the patient started to feel better. They gave her excess fluids and gave her blood pressure medication a little bit earlier and everything came back down. She was frightened when this first occurred. The feeling of choking and the feeling of jaw swelling got better and went away within a few hours. The patient had multiple sclerosis so weakness is always an issue and mobility is always an issue. She knew her tolerance and what she could do. That day they had taken her in a wheelchair from the car to the house and she could not get out of the wheelchair, which was not normal for her. This happened within an hour of the shot. The weakness lingered the longest. That side effect did linger. It took a couple of days. She was using a Hugo again to get herself around the house and believes this extreme weakness has gone away. She was exercising on a stepper when the caller was talking to her. Caller did not believe there had been any lasting effects. Blood pressure shot up: Started within an hour of the vaccine. She had been hypertensive for quite some time historically. Her medication had been keeping it under control. They administered her dose early that day and it brought it down, it did not linger. The patient had been housebound since the pandemic started. The outcome of the event blood pressure shot up was recovering, while the outcome of the event couldn't stand was unknown; and the outcome of the rest of the events was recovered on 25Mar2021.  Information on lot/batch number has been requested.