High blood pressure/Patient reported that his blood pressure the other day was 224/124; migraine; headache; Anxiety level is really high; This is a spontaneous report from a contactable consumer (patient). A 73-year-old male patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: solution for injection, Batch/Lot number was not reported), via an unspecified route of administration on 19Mar2021 (at the age of 73 year) as single dose for covid-19 immunisation. The patient medical history and concomitant medications were not reported. Caller wants to know if the use of Braftovi-Mektovi could cause high blood pressure, he has been taking the combination therapy for almost two years. Three nights ago, he had a "serious problem" with his blood pressure on 26Mar2021 and had to be sent to the emergency room, he cannot get in contact with his doctor because of the holidays. He is also reporting that 2 weeks ago he took the Pfizer Covid-19 vaccine manufactured by Pfizer and developed migraine and severe headache on 26Mar2021 for over a week, he is scheduled to receive the second dose of the vaccine on Friday. He is also having a scan next Wednesday. Patient is currently taking 4 different medications for his hypertension (5 pills per day). Caller mentioned that he might suspend his medication for the weekend until he sees his physician. Call was attempted to get transferred, but lines were too busy, caller was not able to hold on the line as he was not feeling very well, he accepted to get contacted back. Patient received the first dose of the vaccine two weeks ago and developed headaches and migraine, he is currently experiencing high blood pressure issues and is taking 5 different medications for that, he has also been taking Braftovi-Mektovi for 2 years. He is appointed to receive the second dose of the vaccine next Friday and wants to know if he should receive it. Patient reported that he has been experiencing really high blood pressure. Patient stated that he had to go to the emergency room the other night and may have to go again tonight. Patient reported that his blood pressure the other day was 224/124. Patient stated that he is on five different blood pressure medications. Patient stated that he took the Pfizer Covid vaccine two weeks ago and had migraines. Patient stated that his high blood pressure started around this time as well. Patient stated that his anxiety level is really high on Mar2021. I'm in a situation problem here now. I'm taking two Pfizer products here Braftovi and Mektovi (Intent: History) I don't know if you are familiar with these two. It's cancer chemotherapy, he has a diagnosis of Hypertension and takes blood pressure medication. Caller received his first Pfizer Covid 19 Vaccine on 19Mar2021. One week later he experienced elevated blood pressure & headache. Caller asking if he should take the second Pfizer Covid 19 Vaccine due to his experience with the first one. He plays with a band and will be traveling out of the country soon. He needs proof of receiving both vaccines. This case assessed as serious. The patient underwent lab tests and procedures which included blood pressure measurement: 224/124 on unspecified date. Patient visited to emergency room for the event High blood pressure. Therapeutic measures were taken as a result of the event High blood pressure. The outcome of the events was unknown.  No follow-up attempts are possible; information about lot/batch number cannot be obtained.