Vaccine exposure before pregnancy; Have the sensation in feet, in head, in back, in buttock area, consistently in leg, occasionally in  arm; It was very painful; Tingly feeling became back very strongly: In both legs, inside of mouth, in neck, in whole body; Face felt like I was breaking out in a rash; Felt like I was coming with hives; This spontaneous prospective pregnancy case was reported by a consumer and describes the occurrence of PARAESTHESIA (Tingly feeling became back very strongly: In both legs, inside of mouth, in neck, in whole body), MATERNAL EXPOSURE BEFORE PREGNANCY (Vaccine exposure before pregnancy), URTICARIA (Felt like I was coming with hives), FEELING ABNORMAL (Have the sensation in feet, in head, in back, in buttock area, consistently in leg, occasionally in  arm) and RASH (Face felt like I was breaking out in a rash) in a 31-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 016C21A and 003B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Previously administered products included for Product used for unknown indication: TDAP and FLU vaccine. Past adverse reactions to the above products included No adverse event with FLU vaccine and TDAP. Concomitant products included MACROGOL 3350 (MIRALAX) from an unknown date to June 2021 and MINERALS NOS, VITAMINS NOS (PRENATAL VITAMINS [MINERALS NOS;VITAMINS NOS]) for an unknown indication.   On 26-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 23-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. The patient's last menstrual period was on an unknown date and the estimated date of delivery was 10-May-2022. On 25-Apr-2021, the patient experienced PARAESTHESIA (Tingly feeling became back very strongly: In both legs, inside of mouth, in neck, in whole body) and RASH (Face felt like I was breaking out in a rash). 25-Apr-2021, the patient experienced URTICARIA (Felt like I was coming with hives). On an unknown date, the patient experienced MATERNAL EXPOSURE BEFORE PREGNANCY (Vaccine exposure before pregnancy), FEELING ABNORMAL (Have the sensation in feet, in head, in back, in buttock area, consistently in leg, occasionally in  arm) and MYALGIA (It was very painful). The patient was treated with PARACETAMOL (TYLENOL) for Adverse event, at an unspecified dose and frequency and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency. At the time of the report, PARAESTHESIA (Tingly feeling became back very strongly: In both legs, inside of mouth, in neck, in whole body), URTICARIA (Felt like I was coming with hives), FEELING ABNORMAL (Have the sensation in feet, in head, in back, in buttock area, consistently in leg, occasionally in  arm) and RASH (Face felt like I was breaking out in a rash) had not resolved, MATERNAL EXPOSURE BEFORE PREGNANCY (Vaccine exposure before pregnancy) had resolved and MYALGIA (It was very painful) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: normal (normal) Diabetes, thyroids, nutrients deficiency, markers of inflammation. All results came back normal.. On an unknown date, Electromyogram: normal (normal) received an EMG test, to test nerve conduction in patient's legs, and there was no issue..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant product used included Miralax which was stopped in mid June.  Treatment medication included Tylenol for a day and did not notice any change. So did not continue. Then took Benadryl but her symptoms became worse. When she had caffeine, it also seemed to worsen symptoms. So stopped caffeine and alcohol.  After 2 days of second dose, the tingly feeling became back very strongly: In both legs, inside of mouth, in neck, in whole body. It was very painful. Face felt like she was breaking out in a rash, but there was nothing visible and felt like was coming with hives, but there was nothing to see. That lasted for a day or two. But the symptoms were continuing. She had it in feet, in head, in back, in buttock area. Every day feels a little bit different, but it never completely goes away. It was consistently in leg, occasionally in arm. It had not resolved at all.  This case concerns a 31-year-old, female patient with no relevant medical history, who experienced the unexpected events of vaccine exposure before pregnancy, paresthesia, hives, feeling abnormal and expected events of rash and myalgia. Events paresthesia and rash occurred approximately 2 days after the second dose of Spikevax.  The events rash and myalgia are consistent with the current understanding of the mechanism of action of the vaccine. The benefit-risk relationship of Spikevax in not affected by this report.   This case was linked to MOD-2021-272239 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 15-Sep-2021: Follow up received, contains updated information on patient demographics, medical history, lab data, outcome of the event paresthesia updated from unknown to not recovered and added new event: Maternal exposure after vaccination.; Sender's Comments: This case concerns a 31-year-old, female patient with no relevant medical history, who experienced the unexpected events of vaccine exposure before pregnancy, paresthesia, hives, feeling abnormal and expected events of rash and myalgia. Events paresthesia and rash occurred approximately 2 days after the second dose of Spikevax.  The events rash and myalgia are consistent with the current understanding of the mechanism of action of the vaccine. The benefit-risk relationship of Spikevax in not affected by this report.