lost a lot of weight; visit ER 6weeks ago due a sever abdominal pain, could hardly walk; diagnosis was fibromyalgia; I am so exhausted and all most past walking and doing for myself. Work is being almost to much to handle but I am my only support.; joint pain/severe life altering joint pain; headaches; muscle pain/I am in severe life altering muscle pain; severe pain/I am in constant pain; hardly can walk; has limited motion or arm and shoulder; Anxiety and depression is so much worst at this time; having troubles to sleep; This spontaneous case was reported by a consumer and describes the occurrence of PAIN (severe pain/I am in constant pain), GAIT DISTURBANCE (hardly can walk), MUSCULOSKELETAL DISCOMFORT (has limited motion or arm and shoulder), CONDITION AGGRAVATED (Anxiety and depression is so much worst at this time) and INSOMNIA (having troubles to sleep) in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013A21A and 025D2049) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Anxiety and Depression. Concomitant products included CLONAZEPAM, SERTRALINE and COLECALCIFEROL (VITAMINE D) for an unknown indication.   On 30-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 27-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In February 2021, the patient experienced PAIN (severe pain/I am in constant pain), GAIT DISTURBANCE (hardly can walk), MUSCULOSKELETAL DISCOMFORT (has limited motion or arm and shoulder), CONDITION AGGRAVATED (Anxiety and depression is so much worst at this time), INSOMNIA (having troubles to sleep), ARTHRALGIA (joint pain/severe life altering joint pain), HEADACHE (headaches) and MYALGIA (muscle pain/I am in severe life altering muscle pain). On an unknown date, the patient experienced WEIGHT DECREASED (lost a lot of weight), ABDOMINAL PAIN (visit ER 6weeks ago due a sever abdominal pain, could hardly walk), FIBROMYALGIA (diagnosis was fibromyalgia) and FATIGUE (I am so exhausted and all most past walking and doing for myself. Work is being almost to much to handle but I am my only support.). At the time of the report, PAIN (severe pain/I am in constant pain), FIBROMYALGIA (diagnosis was fibromyalgia), ARTHRALGIA (joint pain/severe life altering joint pain) and MYALGIA (muscle pain/I am in severe life altering muscle pain) had not resolved and GAIT DISTURBANCE (hardly can walk), MUSCULOSKELETAL DISCOMFORT (has limited motion or arm and shoulder), CONDITION AGGRAVATED (Anxiety and depression is so much worst at this time), INSOMNIA (having troubles to sleep), WEIGHT DECREASED (lost a lot of weight), ABDOMINAL PAIN (visit ER 6weeks ago due a sever abdominal pain, could hardly walk), HEADACHE (headaches) and FATIGUE (I am so exhausted and all most past walking and doing for myself. Work is being almost to much to handle but I am my only support.) outcome was unknown.            patient had performed some physical therapy and visited a chiropractor patient had preformed several test and lab work but not getting any relief patient had a CT scan. undetermined abdominal and pelvic pain, indicated to visit a gastroenterologist Patient mention that specialist have indicated tests to eliminate suspicion that the pain and weight loss could be due a stomach cancer. Main care doctor didn't recommend patient to have the booster shot. Doctor says it is just Fibromyalgia however she was not diagnosed with this prior to 2nd shot.  concomitant product included Effexor XR 150Mg 1xday Morning   treatment medication included steroid shot  This case concerns a 59-year-old female patient with no relevant medical history, who experienced the unexpected event and Adverse Event of Special Interest, Fibromyalgia. The event occurred on an unknown date after receiving the second dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the second dose was disclosed. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 13-Nov-2021: Significant follow up - new event exhaustion added. outcome of the events (pain, myalgia, fibromyalgia  and arthralgia) updated to not resolved.; Sender's Comments: This case concerns a 59-year-old female patient with no relevant medical history, who experienced the unexpected event and Adverse Event of Special Interest, Fibromyalgia. The event occurred on an unknown date after receiving the second dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the second dose was disclosed. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.