patient had to go to the bathroom so bad that she did not make it to the bathroom in time (peed in her pajamas); It just hurts so much all over, pain; Could hardly walk, didnt make it peed in her PJ; Was "so weak"; Muscle achiness, muscles were "killing" her; Stiff as a board, could hardly get out of bed; This non-serious case was reported by a consumer via call center representative and described the occurrence of walking difficulty in a 77-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included cardiac pain (went to Urgent Care on Friday 10-Mar-2023 for heart pain was prescribed muscle relaxer'). Concurrent medical conditions included eyeglasses wearer.   On 14-MAR-2023, the patient received the 1st dose of Shingrix (intramuscular, left arm). On 15-MAR-2023, 1 days after receiving Shingrix, the patient experienced walking difficulty (Verbatim: Could hardly walk, didnt make it, peed in her PJ), weakness (Verbatim: Was "so weak"), muscle pain (Verbatim: Muscle achiness, muscles were "killing" her) and pain (Verbatim: It just hurts so much all over, pain). In MAR-2023, the patient experienced stiffness (Verbatim: Stiff as a board, could hardly get out of bed). On 16-MAR-2023, the patient experienced activities of daily living impaired (Verbatim: patient had to go to the bathroom so bad that she did not make it to the bathroom in time (peed in her pajamas)). The outcome of the walking difficulty, muscle pain, stiffness and activities of daily living impaired were not recovered/not resolved and the outcome of the weakness was recovered/resolved and the outcome of the pain was recovering/resolving.   It was unknown if the reporter considered the walking difficulty, pain and activities of daily living impaired to be related to Shingrix. The reporter considered the weakness, muscle pain and stiffness to be related to Shingrix.     It was unknown if the company considered the walking difficulty, pain and activities of daily living impaired to be related to Shingrix. The company considered the weakness, muscle pain and stiffness to be related to Shingrix.   Additional Information: GSK receipt date: 16-Mar-2023 This case was self reported by the patient. The patient received Shingrix shot at a pharmacy.  The patient was unable to locate a lot number for the administered vaccine but did provide the contact information for the pharmacy who should have that data on file.  The patient reported that the next morning she got up but could hardly walk, so weak and her muscles were killing her.  On the day of reporting morning when the patient got up still had stiff as a board and could hardly get out of bed. The patient had to go to the bathroom so bad that she did not make it to the bathroom in time (peed in her pajamas).  The patient was calling GSK to see if the muscle achiness would resolve.  Later the patient reported that she was okay.  The patient sleep was all right but then I go to get out of bed and I feel like it just hurts so much all over then it subsides.  After it happened yesterday morning it subsided.  Now it was getting better, pain was not so bad, but I am really stiff in the morning. The reporter did not consent to follow up.  The patient recently moved and does not yet have a primary care physician. After 2 days, the patient experienced activities of daily living impaired. Less than a week, the patient experienced stiffness.