Depression; Body weakness; Dizziness; Falling; Could hardly walk; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID.  A 66-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 26Oct2022 as dose 5 (booster), single (Lot number: GJ3275) at the age of 66 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "Thyroid issues" (unspecified if ongoing), notes: Thyroid issues; "Defibrillator/pacemaker insertion" (unspecified if ongoing); "Muscular dystrophy" (unspecified if ongoing); "Parkinson's" (unspecified if ongoing), notes: Parkinson's. Concomitant medication(s) included: ALPRAZOLAM; CLONAZEPAM. Vaccination history included: BNT162b2 (First Dose: Lot EN6199), administration date: 05Mar2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Falling several times", "Dizziness", "Weakness"; BNT162b2 (Second Dose: Lot ER8733), administration date: 26Mar2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Falling several times", "Dizziness", "Weakness"; BNT162b2 (Third Dose: Lot is either 33030BD or 33030DD.), administration date: 03Dec2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Falling several times", "Dizziness", "Weakness"; BNT162b2 (Fourth Dose: Lot is either FM7553 or FM7533), administration date: 25May2022, when the patient was 66-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "Her body is weak in the leg, arms, hands to the point she can barely walk", "Dizziness"; BNT162b2 (Fourth Dose: Lot is either FM7553 or FM7533), administration date: 25May2022, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Her body is weak in the leg, arms, hands to the point she can barely walk", "Falling several times", "Weakness". The following information was reported: ASTHENIA (non-serious) with onset 2022, outcome "not recovered", described as "Body weakness"; GAIT DISTURBANCE (non-serious) with onset 2022, outcome "not recovered", described as "Could hardly walk"; DEPRESSION (non-serious) with onset 2022, outcome "not recovered"; DIZZINESS (non-serious) with onset 2022, outcome "not recovered"; FALL (non-serious) with onset 2022, outcome "not recovered", described as "Falling". Relevant laboratory tests and procedures are available in the appropriate section.  Additional Information: Daughter which is the caregiver for her mom wanted to know if the onset of depression, body weakness, dizziness and falling were related to the vaccine. Reporter then stated being interested in knowing if there was anything to do to reverse the side effects and how long the vaccine stays in the system. Ever since patient has gotten it (the vaccines) or actually every time she has gotten each dose, she experiences severe depression, her body is weak in the leg, arms, hands to the point she can barely walk and was falling several times. She also experiences dizziness each time, between the dizziness and weakness she has fallen a few times because of it. Reporter was wondering if there was anything she can do to reverse the side effects or help. Reporter states that her mom has had 5 doses of the covid vaccine and all of them are Pfizer. Fifth Dose Bivalent Vaccine was on 26Oct2022 Lot was either GJ3275 or 6J3275. She received it in the Upper Arm she does not know if it was the right or left arm. The reporter clarified that only the Fifth dose was the Pfizer Covid Bivalent Vaccine. The Fifth dose was the worst for her as of side effects. Doses One to Four were the Monovalent Covid Vaccine. Reporter also clarified that each time with each dose, with the last dose being the worst, but each time her mom would experience Depression, Body weakness, and dizziness. During the call, caller's mom said she thought she had muscular dystrophy or something like that. The dizziness was on and off, it was not constant. The side effects happen with each vaccination, however the start of the side effects typically started a few days after getting the vaccine and gets worse. Investigation: She recently had a brain scan clarifying it was actually a CT scan of the brain, back and neck. She also had labs done since she is suppose to be having her hip replaced next Friday. The CT scans results had nothing, when it came back, besides showing that she has some deterioration in the hips. For the labs, she recalls is was Blood work and they did a bacterial swab, she cant remember what bacteria she was positive for but she had an infection, The CT scans and lab work was back in Sep2022 she is guessing since the doctor appointment was in early Oct2022. The patient had no allergies. Reporter states that her mom asked the doctor if she had muscular dystrophy, the doctor ruled that out, the doctor also said Parkinson's is ruled out, He ruled out all of that and said its not what it is, they don't know what it was, but just noticed it comes on every time she gets the covid vaccines. Furthermore, it was reported that Since patient started the vaccine, she overcome with depression, dizziness, and severe weakness in her arms and legs. She have fallen many times due to the weakness and dizziness. She received her last dose of the Pfizer vaccine on Wednesday 26Oct. The next day her depression was out of control and she could hardly walk. She came to realize it was the vaccine causing her problems.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201296552 Same patient, different dose and event.;US-PFIZER INC-202201296553 Same patient, different dose and event.;US-PFIZER INC-202201296554 Same patient, different dose and event.;US-PFIZER INC-202201296551 Same patient, different dose and event.;