nerve neuropathy; lymphoma getting worse; Premature atrial contraction had gotten worse; Premature atrial contraction had gotten worse/ lymphoma getting worse; his arthritis is flaring up and "acting up".; pain; This is a spontaneous report from a consumer (patient) via regulatory authority. A 56-years-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration, administered in arm left on 14Apr2021 15:00 (Lot Number: ER8731) as dose 2, single at the age of 56-years-old for covid-19 immunization. Medical history included ongoing rheumatoid arthritis, ongoing lupus, ongoing lupus anticoagulant, this leaves him immunocompromised, ongoing premature atrial contraction, ongoing lymphoma. Patient said that he was included on the high risk priority for the vaccine. He has lupus, rheumatoid arthritis and other things going on. Concomitant medication included hydroxychloroquine sulfate (HYDROXYCHLOROQUINE ACTAVIS) ongoing for lupus. The patient received first dose of bnt162b2 (Lot: EM9810) on 16Mar2021 around 1pm in the left arm for covid-19 immunization. Prior vaccinations (within 4 weeks): none. AEs following prior vaccinations: none. After getting the second shot of the vaccine, his arthritis was flaring up and "acting up". The pain is "very bad" and that his doctor was telling him it went back to the vaccine. He also stated that the last month was "brutal" since he can barely get up from his chair and his bed and that he was not allowed to take Ibuprofen and most of rheumatoid arthritis medications. The patient explained that for the for past 2 months he has been feeling crappy and there are days when he cannot walk related to the arthritis. He mentioned that he had a lymphoma stage 4 before and it has gotten worse as well after the second dose. The patient clarified that his lymphoma has been inflamed. He also stated that he had premature atrial contraction (PAC), this has flared up too. Premature atrial contraction had gotten worse and confirmed that he was experiencing symptoms of chest pain, shortness of breath, and a pounding heart. The patient notes that with his PAC, he noticed his heart was palpating and racing more. Since having chemo he had side effects after that but this was 3 years ago and he had nothing since then until now. The doctor did not know if this is related to getting the vaccine. Patient felt like maybe he shouldn't have gotten the vaccines. He was taking tramadol for pain but he did not want to be on pain killers and did not want to go back on taking hydrocodone. Patient also reiterated that before getting the shot he was okay and now he was moving "backwards". He also added that nerve neuropathy is what he got out of it. Patient also said his hydroxychloroquine and tramadol are not working anymore since getting the vaccine and wants to know for potential interaction. All the events were noticed in Jun2021. For arthritis, this was noticed about a month afterward but he didn't know until Jun2021 what was really going on. He went to his rheumatologist and they did a sedimentation rate that showed his inflammatory marks were like they were when doing chemo. They hadn't been that level for 3 years, since he was on chemo. She also noticed the lymphoma in his right arm was swollen. This was the same time, in Jun2021. The patient reported he had rheumatoid arthritis and the doctor think it is a flare up of that. He reported joint pain, when he sits it is hard to get up. Patient confirmed this is the arthritis mentioned above, it is all the same event. The patient stated he thought he was getting sick again, that his cancer was back or something was going on. The oncologist did note that his lymph node were going down. It was confirmed this statement is related to the above mentioned events already covered in the report. AEs require a visit to: physician office (Patient also stated he saw his doctor's regularly). Relevant test included: Sedimentation rate: 24 on Jun2021; 22 on 02Jul2021. Outcome of the event lymphoma getting worse, premature atrial contraction had gotten worse, arthritis is flaring up was not recovered, of other events was unknown.