hot sensation through the veins/hot sensation going through/like menopause-related hot flashes; sudden round of diarrhea; burning sensation/like burning up; Little achy/aching; low grade fever; chills; nausea; sore arm; This spontaneous case was reported by a consumer and describes the occurrence of FEELING HOT (hot sensation through the veins/hot sensation going through/like menopause-related hot flashes), DIARRHOEA (sudden round of diarrhea), BURNING SENSATION (burning sensation/like burning up), PAIN (Little achy/aching) and PYREXIA (low grade fever) in a 47-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 069F21A, 013M20A and 013M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Pain. Concomitant products included FLUTICASONE PROPIONATE (FLONASE [FLUTICASONE PROPIONATE]), ESCITALOPRAM OXALATE (LEXAPRO), IBUPROFEN, PARACETAMOL (TYLENOL [PARACETAMOL]) and ACETYLSALICYLIC ACID (ASPIRINE) for an unknown indication.   On 02-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-Nov-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced PAIN IN EXTREMITY (sore arm). On 13-Nov-2021, the patient experienced FEELING HOT (hot sensation through the veins/hot sensation going through/like menopause-related hot flashes), DIARRHOEA (sudden round of diarrhea), BURNING SENSATION (burning sensation/like burning up), PAIN (Little achy/aching), PYREXIA (low grade fever), CHILLS (chills) and NAUSEA (nausea). The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) on 13-Nov-2021 for Ache, at an unspecified dose and frequency. At the time of the report, FEELING HOT (hot sensation through the veins/hot sensation going through/like menopause-related hot flashes), DIARRHOEA (sudden round of diarrhea), BURNING SENSATION (burning sensation/like burning up), PAIN (Little achy/aching), PYREXIA (low grade fever), CHILLS (chills) and NAUSEA (nausea) had not resolved and PAIN IN EXTREMITY (sore arm) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 13-Nov-2021, Body temperature: 99.6 f (High) 99.6 F.         After the booster dose she had a sore arm, and the next day on 13-Nov-2021 (Saturday morning), she was a little achy, took Tylenol, but since then she keeps getting these waves (ongoing) nausea, chills, hot sensation through the veins, aching, and a sudden round of diarrhea, low grade fever (99.6°F). It goes away and then one hour later everything starts all over again. She was taking Tylenol, ibuprofen, iced-cold water and ensure drinks and eating crackers. The patient describes a burning sensation, like menopause related hot flashes (for what she has heard others those hot flashes feel like), it was a hot sensation going through, like burning up. They last 3-4 minutes and then they repeat about every hour.  She forgot the concomitant medication Flonase sometimes and had regular pain so she takes a combination of pain killers. She was dosage sensitive.   This case was linked to MOD-2021-390060, MOD-2021-390090 (Patient Link).