constipation; Lost appetite; Arthritic pain in thumbs, knees; Yawning; Mentally drained; Excruciating pain in vagina; Arthritic pain in back; This spontaneous case was reported by a consumer and describes the occurrence of CONSTIPATION (constipation), YAWNING (Yawning), MENTAL FATIGUE (Mentally drained), VULVOVAGINAL PAIN (Excruciating pain in vagina) and DECREASED APPETITE (Lost appetite) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 030120A and 025J20-2A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Knee osteoarthritis (Left knee), Thumb osteoarthritis (Left thumb) and Back arthritis.   On 08-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 03-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 04-Feb-2021, the patient experienced YAWNING (Yawning), MENTAL FATIGUE (Mentally drained), VULVOVAGINAL PAIN (Excruciating pain in vagina) and ARTHRALGIA (Arthritic pain in thumbs, knees). On 12-Feb-2021, the patient experienced CONSTIPATION (constipation) and DECREASED APPETITE (Lost appetite). In February 2021, the patient experienced ARTHRALGIA (Arthritic pain in back). At the time of the report, CONSTIPATION (constipation), YAWNING (Yawning), MENTAL FATIGUE (Mentally drained), VULVOVAGINAL PAIN (Excruciating pain in vagina) and DECREASED APPETITE (Lost appetite) outcome was unknown and ARTHRALGIA (Arthritic pain in back) and ARTHRALGIA (Arthritic pain in thumbs, knees) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 18-Feb-2021, Abdominal X-ray: (normal) Nonobstructive bowel gas pattern. Normal heart size. Lungs grossly clear with minimal infiltrate left base not excluded. Constipation.. On 18-Feb-2021, Alanine aminotransferase (7-40): 31 normal. On 18-Feb-2021, Aspartate aminotransferase (8-42): 24 normal. On 18-Feb-2021, Basophil count (0.0-0.2): 0.0 normal and 0 (normal) Normal range not provided. On 18-Feb-2021, Blood albumin (3.4-4.7): 3.6 normal. On 18-Feb-2021, Blood alkaline phosphatase (39-139): 105 normal. On 18-Feb-2021, Blood bilirubin (0.1-1.2): 0.3 normal. On 18-Feb-2021, Blood calcium (8.5-10.7): 9.5 normal. On 18-Feb-2021, Blood chloride (96-112): 104 normal. On 18-Feb-2021, Blood creatinine (0.57-1.11): 0.75 normal. On 18-Feb-2021, Blood potassium (3.5-5.0): 4.3 normal. On 18-Feb-2021, Blood sodium (135-146): 142 normal. On 18-Feb-2021, Blood test (70-110): 105 normal. On 18-Feb-2021, Blood thyroid stimulating hormone (0.35-5.00): 3.85 normal. On 18-Feb-2021, Blood urea (5-25): 11 normal. On 18-Feb-2021, Carbon dioxide (21-32): 27 normal. On 18-Feb-2021, Eosinophil count (0.0-0.8): 0.1 normal and 2 (normal) Normal range not provided. On 18-Feb-2021, Glomerular filtration rate: 84 normal. On 18-Feb-2021, Haematocrit (34.5-42.8): 38.8 normal. On 18-Feb-2021, Haemoglobin (11.9-15.0): 12.7 normal. On 18-Feb-2021, Lymphocyte count (0.8-5.0): 1.6 normal and 23 (normal) Normal range not provided. On 18-Feb-2021, Mean cell haemoglobin concentration (31.7-35.5): 32.7 normal. On 18-Feb-2021, Mean cell volume (80.0-100.0): 95.4 normal. On 18-Feb-2021, Mean platelet volume (6.1-9.6): 7.1 normal. On 18-Feb-2021, Monocyte count (0.2-1.4): 0.5 normal and 8 (normal) Normal range not provided. On 18-Feb-2021, Neutrophil count (1.8-9.2): 4.7 normal and 67 (normal) Normal range not provided. On 18-Feb-2021, Nucleated red cells (0-2): 0/100 normal. On 18-Feb-2021, Platelet count (150-440): 422 normal. On 18-Feb-2021, Protein albumin ratio (6.2-8.2): 7.9 normal. On 18-Feb-2021, Red blood cell count (3.71-5.19): 4.06 normal. On 18-Feb-2021, Red cell distribution width (10.6-14.5): 11.6 normal. On 18-Feb-2021, White blood cell count (4.6-12.4): 7.0 normal.         Concomitant medications were not provided. Treatment medications included Steroid shot.   This case was linked to MOD-2021-065835 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 21-Apr-2021: Follow up received on 21-APR-202 and it contains No New Information On 29-Jun-2021: Follow-up received on 29/6/21, contains no new information.