hypermobile Ehlers Danlos Syndrome; Skin over all of body also felt sensitive/stinging as if after a sunburn; Skin over all of body also felt sensitive/stinging as if after a sunburn; body aches amplified; fatigue; Had a fever of 100 F 12 hours post injection of 3rd booster shot; Also had significant to severe joint; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 26 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), intramuscular, administered in arm right, administration date 06Oct2021 07:30 (Lot number: FF8841) at the age of 26 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Hypermobile Ehlers Danlos syndrome" (unspecified if ongoing); "anxiety" (unspecified if ongoing); "migraines with aura" (unspecified if ongoing); "ParaGard IUD" (unspecified if ongoing). Concomitant medication(s) included: PROGESTERONE; ALLEGRA; ADVIL [IBUPROFEN]; ALEVE. Past drug history included: Augmentin, reaction(s): "Known allergy-Slight possible allergy/reaction to Augmentin". Vaccination history included: Bnt162b2 ([{prev dose product=COVID 19, prev dose brand=Pfizer BioTech, prev dose brand unknown=False, prev dose lot number=EN5318, prev dose lot unknown=False, prev dose administrator route=Intramuscular, prev dose administration date=16Feb2021 , prev dose number=2, prev dose vaccine location=Right arm}), administration date: 16Feb2021, when the patient was 26 years old, for Covid-19 immunization; Bnt162b2 ({prev dose product=COVID 19, prev dose brand=Pfizer BioTech, prev dose brand_unknown=False, prev dose lot number=EN5318, prev dose lot unknown=False, prev dose administrator route=Intramuscular, prev dose administration date=25Jan 2021, prev dose number=1, prev dose vaccine location=Right arm}]), administration date: 25Jan2021, when the patient was 26 years old, for Covid-19 immunization; Flu shot (other vaccine 4weeks details, other vaccine 4weeks product=Flu shot at Pfizer flu shot clinic, other vaccine 4weeks vaccine date: 29Sep2021, other vaccine 4weeks dose number=1, other vaccine 4weeks vaccine location=Right Arm), administration date: 29Sep2021, when the patient was 26 years old, for immunisation. The following information was reported: EHLERS-DANLOS SYNDROME (non-serious) with onset 06Oct2021 19:00, outcome "recovering", described as "hypermobile Ehlers Danlos Syndrome"; SENSITIVE SKIN (non-serious), PAIN OF SKIN (non-serious) all with onset 06Oct2021 19:00, outcome "recovering" and all described as "Skin over all of body also felt sensitive/stinging as if after a sunburn"; PAIN (non-serious) with onset 06Oct2021 19:00, outcome "recovering", described as "body aches amplified"; FATIGUE (non-serious) with onset 06Oct2021 19:00, outcome "recovering", described as "fatigue"; PYREXIA (non-serious) with onset 06Oct2021 19:00, outcome "recovering", described as "Had a fever of 100 F 12 hours post injection of 3rd booster shot"; ARTHRALGIA (non-serious) with onset 06Oct2021 19:00, outcome "recovering", described as "Also had significant to severe joint". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of ehlers-danlos syndrome, sensitive skin, pain of skin, pain, fatigue, pyrexia, arthralgia.  Additional information: Had a fever of 100 F 12 hours post injection of 3rd booster shot following taking Advil in an attempt to reduce body aches and arm soreness post shot. Also had significant to severe joint and body aches amplified due to hypermobile Ehlers Danlos Syndrome. Skin over all of body also felt sensitive/stinging as if after a sunburn from about 12 hours post injection through the following morning. The next day also experienced more body aches and fatigue but fever had reduced to 98 F. Back to relatively normal feeling and no fever second day post injection. Patient did not experience Covid prior vaccination and did not test Covid post vaccination.  No follow-up attempts are possible. No further information is expected.