This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (Arthritis), INTERVERTEBRAL DISC PROTRUSION (Bulging disks), SACRAL PAIN (SI joint pain/Lower back pain) and MYALGIA (Muscle pain in the lower back and left hip) in a 63-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 028L20A) for COVID-19 vaccination. Patient had no allergy and no Covid test was done. On 28-Aug-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced ARTHRITIS (Arthritis), INTERVERTEBRAL DISC PROTRUSION (Bulging disks), SACRAL PAIN (SI joint pain/Lower back pain) and MYALGIA (Muscle pain in the lower back and left hip). The patient was treated with PREDNISONE at an unspecified dose and frequency. At the time of the report, ARTHRITIS (Arthritis), INTERVERTEBRAL DISC PROTRUSION (Bulging disks), SACRAL PAIN (SI joint pain/Lower back pain) and MYALGIA (Muscle pain in the lower back and left hip) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Angiogram: not reported Not reported. On an unknown date, X-ray: bulging disks bulging disks. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. No concomitant medications were reported. It was reported that patient had 1st booster dose: 03-Nov-2021, intramuscular injection, Lot : 005C21A Expiration: Unknown and 2nd booster dose: 12-May-2022, intramuscular injection, Lot: 057M21A Expiration: 13Aug2022. Treatment was reported as left joint injection that has dye and cortisone in it, did an MRA. Company Comment: This spontaneous case concerns a 63-year-old, female patient with no medical history reported who experienced the unexpected, non-serious adverse event of special interest of Arthritis which occurred on unspecified interval after administration of the first dose of mRNA-1273 vaccine. The event was reported along with other non-serious events of muscle pain in the lower back and left hip. Patient initially presented with low back pain five months after vaccination. She consulted a physician and was intermittently treated with steroid injections in the sacroiliac joint. Further work up revealed bulging disks on unspecified vertebral region on x-ray. The anatomic location of arthritis was not reported in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report. This case was linked to MOD-2022-568052 (Patient Link). Sender's Comments: This spontaneous case concerns a 63-year-old, female patient with no medical history reported who experienced the unexpected, non-serious adverse event of special interest of Arthritis which occurred on unspecified interval after administration of the first dose of mRNA-1273 vaccine. The event was reported along with other non-serious events of muscle pain in the lower back and left hip. Patient initially presented with low back pain five months after vaccination. She consulted a physician and was intermittently treated with steroid injections in the sacroiliac joint. Further work up revealed bulging disks on unspecified vertebral region on x-ray. The anatomic location of arthritis was not reported in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.