breast cancer/ two giant tumors in her left breast; really bad flare up of her Psoriasis; feeling like have the flu; nervous wreck; anxious; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 67 year-old female patient received bnt162b2 (COMIRNATY), administration date 09Mar2021 (Lot number: EN6205) at the age of 66 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Psoriasis" (ongoing), notes: diagnosed at age 16; "Flu" (unspecified if ongoing); "frozen shoulder" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Comirnaty (Dose: 1st, Lot Number: EL9269), administration date: 16Feb2021, when the patient was 66 years old, for Covid-19 immunization.The following information was reported: BREAST CANCER FEMALE (medically significant) with onset 03Apr2021, outcome "not recovered", described as "breast cancer/ two giant tumors in her left breast"; PSORIASIS (non-serious) with onset Mar2021, outcome "not recovered", described as "really bad flare up of her Psoriasis"; INFLUENZA LIKE ILLNESS (non-serious) with onset 2021, outcome "not recovered", described as "feeling like have the flu"; NERVOUSNESS (non-serious) with onset 2021, outcome "not recovered", described as "nervous wreck"; ANXIETY (non-serious) with onset 2021, outcome "not recovered", described as "anxious". The patient underwent the following laboratory tests and procedures: mammogram: (2021) unknown results. Clinical course: After 2nd dose of the Pfizer COVID vaccine back in Mar2021, 2 weeks later (as reported) her psoriasis went nuts and it has never calmed down. She has never had an outbreak like that before and she had it since she was 16 years old and she was now 67 years old. Psoriasis was a pain in the ass and, she would say, it was a moderate case. Now she has big patches everywhere and didn't know if at some point if it will settle down. She didn't want the booster but her dermatologist talked her into it because the dermatologist said that if the caller were to get COVID then her psoriasis flare would be much worse. The patient was a nervous wreck already because 2 weeks after she had the 2nd Pfizer COVID vaccine she was diagnosed with breast cancer. She got the two shots done and then she got breast cancer, which was there already but unfortunately the mammogram didn't pick it up, and she has had psoriasis everywhere then they said to get the booster and there was no end and then she will have to tell her story over again. She just wanted to know if she is okay and if it is normal with this skin reaction. She didn't want to go to the emergency room with whelps but that's how anxious she was, she was freaking out. Patient had second shot, then 2 weeks later she had noticed that her psoriasis was developing in placed that she never had it on before. It was starting out as large patches but she didn't think too much of it after a while because a few weeks later she was diagnosed with breast cancer so the psoriasis took a back seat. Then she thought about how close the psoriasis outbreak was to her vaccine and how things didn't settle. She knew what to do when she has an outbreak and it didn't help. She then realized that there had to be a connection between the vaccine and the explosion of her psoriasis because it began literally 2 weeks after her 2nd dose. She has done research about a lot of things in the last few months and she was some information about some things that people were reporting, not relating to psoriasis per say. When she talked to the National Psoriasis Foundation they said if even she was reporting her flare they still recommend to get the vaccine. In her research she saw information about people would have other things from the vaccine. Breast Cancer- That was diagnosed on 03Apr2021 but there was no way that is connected to the vaccine because it was huge, it was two giant tumors in her left breast. If it wasn't for her frozen shoulder and going to physical therapy she never would have caught it. She had a diagnostic mammogram when they had found it and she already knew that she had breast cancer but by the look of it. When one lay on the bed and there was a tumor sticking straight up one knew it's cancer. Some people that it was a reaction but it was on the other side of her body and it was as hard as a rock and it was standing straight up. When they did the mammogram they couldn't see it and it was not related (as reported).   Follow-up attempts are completed. No further information is expected.