On all four injection sites I had knots underneath my skin; pain that radiates down my arm to my right thumb/ pain on occasion traveling down my arm into my right thumb; My right upper arm where two of the injections were given stay sore; carpal tunnel syndrome yet highly arthritic.; carpal tunnel syndrome yet highly arthritic.; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP), Program ID: (005570). The reporter is the patient.  A 66-year-old female patient received BNT162b2 (BNT162B2), on 04Jan2021 at 10:00 as dose 1, single (Lot number: EL0142) at the age of 66 years intramuscular, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Retinal vein occulusion", start date: 01Aug2018 (ongoing), notes: Pertinent details: eye lead injection every 4 to 6 weeks. The patient's family history included: "High blood pressure" (ongoing), notes: Onset date: 10 years ago, Pertinent details: metoprolol succinate 100 mg 1x a day; "Thyroid" (ongoing), notes: Onset date: 10 years ago, Pertinent details: Levothyroxine sodium 25 mcg; "Stroke" (unspecified if ongoing); "Alzheimers" (unspecified if ongoing), notes: Alzheimers; "Arthritis (RA)" (unspecified if ongoing), notes: Arthritis (RA); "eye disease" (unspecified if ongoing), notes: eye disease. Concomitant medication(s) included: METOPROLOL SUCCINATE taken for hypertension; LEVOTHYROXINE SODIUM taken for thyroid disorder. The following information was reported: VACCINATION SITE PAIN (non-serious) with onset Jan2021, outcome "not recovered", described as "My right upper arm where two of the injections were given stay sore"; VACCINATION SITE NODULE (non-serious) with onset Jan2021, outcome "unknown", described as "On all four injection sites I had knots underneath my skin"; CARPAL TUNNEL SYNDROME (non-serious), ARTHRALGIA (non-serious) all with onset Jan2021, outcome "unknown" and all described as "carpal tunnel syndrome yet highly arthritic."; PAIN IN EXTREMITY (non-serious) with onset Jan2021, outcome "not recovered", described as "pain that radiates down my arm to my right thumb/ pain on occasion traveling down my arm into my right thumb". Therapeutic measures were taken as a result of pain in extremity, vaccination site pain.  Additional information: The patient reported that first Pfizer injection was given on 04Jan2021 and still experience pain that radiated down, her arm to her right thumb. On all four injection sites she had knots underneath my skin. she have had a nerve conduction test for carpal tunnel syndrome yet highly arthritic. She have had 2 vaccines for COVID that were Pfizer on dates 04Jan2021 & 26Jan2021. Then two Pfizer boosters on 20Aug2021 & 01Oct2022. Her right upper arm where two of the injections were given stay sore along with pain on occasion traveling down her arm into her right thumb. That has been ongoing for quite awhile and she thought it was her side sleeping but bought a spinal alignment pillow and it still persisted. The pain was not severe but was there.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201304974 Same patient, different dose/ AE;US-PFIZER INC-202201304975 Same patient, different dose/ AE;US-PFIZER INC-202201304976 Same patient, different dose/ AE;US-PFIZER INC-202201304977 Same patient, different dose/ AE;