inflammation in mid section of back/4 body parts undergoing inflammation; hard to get out of bed; excruciating pain; her right foot inflamed; got a large bump on foot; Very sore to walk on; nose swollen up; pain behind eyes and into the head; when nose is swollen gets headaches; karate chopped the top of her shoulder; shoulder never healed; shoulder sore, painful; This spontaneous case was reported by a patient and describes the occurrence of MUSCULOSKELETAL DISCOMFORT (karate chopped the top of her shoulder), LIGAMENT SPRAIN (shoulder never healed), INFLAMMATION (inflammation in mid section of back/4 body parts undergoing inflammation), BEDRIDDEN (hard to get out of bed) and PAIN (excruciating pain) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 003A21A and 031L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 14-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 16-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 17-Mar-2021, the patient experienced MUSCULOSKELETAL DISCOMFORT (karate chopped the top of her shoulder), LIGAMENT SPRAIN (shoulder never healed) and ARTHRALGIA (shoulder sore, painful). On an unknown date, the patient experienced INFLAMMATION (inflammation in mid section of back/4 body parts undergoing inflammation), BEDRIDDEN (hard to get out of bed), PAIN (excruciating pain), OEDEMA PERIPHERAL (her right foot inflamed), LIMB DISCOMFORT (got a large bump on foot), PAIN IN EXTREMITY (Very sore to walk on), NASAL OEDEMA (nose swollen up), EYE PAIN (pain behind eyes and into the head) and HEADACHE (when nose is swollen gets headaches). The patient was treated with PREDNISONE at an unspecified dose and frequency. At the time of the report, MUSCULOSKELETAL DISCOMFORT (karate chopped the top of her shoulder), LIGAMENT SPRAIN (shoulder never healed), INFLAMMATION (inflammation in mid section of back/4 body parts undergoing inflammation), BEDRIDDEN (hard to get out of bed), PAIN (excruciating pain), OEDEMA PERIPHERAL (her right foot inflamed), LIMB DISCOMFORT (got a large bump on foot), PAIN IN EXTREMITY (Very sore to walk on), NASAL OEDEMA (nose swollen up), EYE PAIN (pain behind eyes and into the head), ARTHRALGIA (shoulder sore, painful) and HEADACHE (when nose is swollen gets headaches) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In April 2021, Blood test: results not reported Inconclusive. In April 2021, Magnetic resonance imaging: results not reported Inconclusive. In April 2021, X-ray: results not reported inconclusive.         No concomitant medication provided. In April patient has  went to various doctors who sent her to rheumatologist, who sent her to an ENT doctor, who sent her to a foot doctor. She has visited a neurologist, a chiropractor, acupuncturists, all these doctors, and has cost her a lot of money. Most of the doctors said these reactions were probably related to the vaccine, they can't explain how to treat it.