A little asthma; Lymphedema; Bladder infection; Breathlessness, I was breathless when I walked & talked, or picked up something; This spontaneous case was reported by a consumer and describes the occurrence of DYSPNOEA (Breathlessness, I was breathless when I walked & talked, or picked up something) in an 81-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 007M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Bladder infection (Chronic, had some trouble with this some time ago, a year ago and it kind of resurfaced.) and Glaucoma. Concurrent medical conditions included Drug allergy (Some years ago she had a situation treating her glaucoma.), Type 2 diabetes mellitus (diabetic) and Heartbeats irregular (Since patient was 20 years old.). Concomitant products included METFORMIN for Type 2 diabetes mellitus, IRON and CALCIUM for an unknown indication.    On 20-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 22-Feb-2021, the patient experienced DYSPNOEA (Breathlessness, I was breathless when I walked & talked, or picked up something) (seriousness criterion medically significant). On 23-Feb-2021, the patient experienced CYSTITIS (Bladder infection). On an unknown date, the patient experienced ASTHMA (A little asthma) and LYMPHOEDEMA (Lymphedema). The patient was treated with ALPRAZOLAM ongoing since an unknown date for Bladder infection, at a dose of 25 mg once a day. At the time of the report, DYSPNOEA (Breathlessness, I was breathless when I walked & talked, or picked up something), CYSTITIS (Bladder infection), ASTHMA (A little asthma) and LYMPHOEDEMA (Lymphedema) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Oxygen saturation: 97-98 (normal) At about 97 & 98. On an unknown date, X-ray: normal (normal) Checked her lungs and did x-rays and they were ok..     mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) dosing remained unchanged.       Patient had been to primary Dr several times who did every test known and couldn't find anything wrong. The patient had good days and bad, it was erratic.  Company Comment: This case concerns an 81 year-old female wit ha medical history of Bladder infection, who experienced the unexpected events of Dyspnoea and Cystitis. The event of Dyspnoea occurred 2 days after the first dose of Moderna COVID-19 Vaccine, while the event of Cystitis occurred 3 days after the dose. The medical history of Bladder Infection remains a cofounder.The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.   This case was linked to MOD-2021-333553 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 27-Sep-2021: Follow-up contains information regarding case seriousness (case upgraded to serious), patient details (date of birth and age), and current condition.; Sender's Comments: This case concerns an 81 year-old female wit ha medical history of Bladder infection, who experienced the unexpected events of Dyspnoea and Cystitis. The event of Dyspnoea occurred 2 days after the first dose of Moderna COVID-19 Vaccine, while the event of Cystitis occurred 3 days after the dose. The medical history of Bladder Infection remains a cofounder.The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.