lost complete feeling in on the right side of her face, including her ear and inside of mouth; Shingles; woke up in the middle of the night; Numbness; severe headaches; creepy crawly feeling under her skin on the top right side of her head; This is a spontaneous report from a contactable consumer (patient). A 45-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Left Upper on 02May2021 (Lot Number: EW0182) as 2ND DOSE, SINGLE for covid-19 immunisation; apremilast (OTEZLA), oral from an unspecified date (Lot Number: F2671A; Expiration Date: May2023), at 30 mg 2x/day for psoriatic arthropathy; prednisone, oral from an unspecified date (Batch/Lot number was not reported), at 7 mg, 1x/day for psoriatic arthropathy. Vaccination Facility Type: Pharmacy/Drug Store. Vaccine Administered at Military Facility: No. Medical history included allergy alert test negative, immunology test, respiratory distress, cytogenetic abnormality, endocrine test abnormal, diabetes mellitus, obesity, psoriatic arthropathy. Had no other vaccines the same day and no problems with vaccines in the past. The patient previously received the first dose of bnt162b2 (lot number EN6205) on 04Apr2021 at left upper arm for covid-19 immunisation without adverse event. The patient's concomitant medications were not reported. The patient was seen at the emergency room last Thursday and was diagnosed and began treatment for shingles (on 20May2021). She had lost complete feeling in on the right side of her face, including her ear and inside of mouth. It really started on the 8th or 9th of May with a severe headache that she ignored for about a week. The headaches were debilitating and she didn't got to the emergency room until she lost feeling. Before the lost feeling she had the creepy crawly feeling under her skin on the top right side of her head (from May2021) and then had the headaches that were so severe they woke her up from dead out of her sleep. Wednesday, 19May2021 she woke up in the middle of the night from the debilitating pain from the headaches out of her sleep. Then she went to the emergency room the 20th since at that point she lost complete feeling. She is being treated with medication, a broad spectrum antiviral, which is no fun, but it's working. Although it's not completely gone, it is better than it was, in terms of the numbness (from May2021). Was given generic Valtrex, valacyclovir hcl 1 gram to take three times daily. Mentions she had to stop her other medicines for to her underlying condition, Psoriatic arthritis, a rheumatoid condition, which is why she is reporting this. She has had this for 23 years. She had to stop the Otezla and Prednisone she takes concurrently when she got the vaccine. Told she can't take theses with the antivirals, so she is screwed right now. Was supposed to start on Xeljanz, but was told not to until after she got the vaccine, but then after the Covid shots she got the shingles then they told her not to start the Xeljanz until after the shingles. Later mentions she takes other medication for psoriatic arthritis and the doctor did do testing to rule out other issues and check her kidney functions since she is on an antiviral, more labs, a CT scan with contrast to rule out acute stroke. Her kidneys are fine and there were no issues in the veins or arteries of her brain. The events require a visit to Emergency Room. The outcome of Facial paralysis, Shingles and Numbness was not recovered. The outcome of others was unknown.