I took 1000 mg of Tylenol, one hour before my vaccination appointment time on 9/10/21. After this injection, I felt no pain - it was nothing like the first vaccine on 8/20/21.  I continued to alternate 600 mg of ibuprofen and 1000 mg of Tylenol every 4 hours until I went to bed around 10:30pm. When I went to bed that night there was mild soreness, which I expected, but otherwise I felt fine.  At 330 am on 9/11/21, my left arm woke me up throbbing.  There was a lump under my arm, and I was hurting at the injection site.  I also had a slight fever (100.6, axillary), so I took 1000 mg of Tylenol since it had been 6 hours without either. By mid-morning, there was more swelling under my L arm going towards my elbow, and by that afternoon it had started making its way across my chest.  I could not actively move my arm away from my body, and when I would use my right hand to assist with movement, my chest / arm would throb.  My resting heart rate was high (for me).  I became lightheaded and nauseated every time I got up (my chest/arm would throb, and it became difficult to get a full breath when walking) (HR into the 130's just walking to the bathroom).  My fever continued (100.6 to 102, axillary), even with alternating Tylenol / Advil every 4 hours.  By Saturday night, I stopped taking Advil because I started to notice that I felt worse after taking it, so I just took Tylenol every 6 hours.  Surprisingly, I slept well through the night on Saturday (only waking up to help reposition my left arm).  Sunday morning, there as more swelling than the day before, but I did not feel like I had a fever, so I only took 500 mg of Tylenol to help with the pain.  I took a shower and within minutes of drying off, I began with the "pin / needles / itchy" feeling in both legs and my left (full) arm (please see reaction to 1st vaccine in "additional information").  This time was more intense than ever before, I was in tears.  This event lasted about 40 minutes.  As the day went on the pain continued to get worse, I started to notice more of a red area around the injection site.  By that evening, my temperature was back to 101.2, axillary.  The throbbing chest/arm pain was so intense at one point that I considered going to the emergency room, which I was really trying to avoid.  I continued to elevate/ice and take Tylenol every 6 hours and ended up at the Urgent Care on 9/13/21.  After that appointment, I was started on 2000 mg of Vitamin C (3x day), 50-100 mg Zinc (1x day), and 325 mg Aspirin (x 2 yesterday, then x 1 for 7-10 days).  Today (9/14/21) if the first day since Friday that I do not feel like I am burning up from the inside out, although I am still taking Tylenol for the pain.  My arm is still swollen, but it seems to be receding from my chest area.  I am trying to more my arm more today to let the under arm "breath".  I feel like I may be getting a rash in the fold of my swelling pocket under my arm.  The redness around my injection site it still hard and very warm to the touch. It is beginning to itch today.  My endurance is still low, but I can say I feel "weak" with walking up our stairs than just walking 20 feet to the bathroom today, which is a plus.