By Saturday, the red area was about 6-inches wide, itchy, and painful.; By Saturday, the red area was about 6-inches wide, itchy, and painful.; "I" also maintained a fever hovering around 100 all day; On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6- inches wide, itchy, and painful.; On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6-inches wide, itchy, and painful.; Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body became restless.; Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body becamerestless.; Primary immunisation: MODERNA; Booster: COMIRNATY; dose number=3; "I" was unable to sleep Thursday night.; This is a spontaneous report from a contactable reporter (consumer or other non-HCP). The reporter is the patient.   A 49-year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 13Jan2022 at 08:30 (Lot number: FD7218)at the age of 49 Year(s) as dose 3 (booster), single for COVID-19 immunisation. Relevant medical history included: "Breast cancer" start date: an unknown date in 2006 (unspecified if ongoing) and "Breast cancer" start date: an unknown date in 2012 (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Moderna covid-19 vaccine (DOSE 1, SINGLE; Lot Number: unknown; Route of administration: unspecified), for COVID-19 immunisation, reaction(s): "No adverse reaction" and Moderna covid-19 vaccine (DOSE 2, SINGLE; Lot Number: unknown; Route of administration: unspecified), for COVID-19 immunisation, reaction(s): "No adverse reaction".  The following information was reported: INTERCHANGE OF VACCINE PRODUCTS (non-serious) with onset 13Jan2022 at 08:30, outcome "unknown", described as "Primary immunisation: MODERNA; Booster: COMIRNATY"; IMMUNISATION (non-serious) with onset 13Jan2022 at 08:30, outcome "unknown", described as "dose number=3"; PAIN IN EXTREMITY (non-serious) with onset 13Jan2022 at 20:30, outcome "not recovered", described as "Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body became restless"; RESTLESSNESS (non-serious) with onset 13Jan2022 at 20:30, outcome "not recovered", described as "Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body became restless"; INSOMNIA (non-serious) with onset 13Jan2022, outcome "not recovered", described as ""I" was unable to sleep Thursday night"; VACCINATION SITE ERYTHEMA (non-serious) with onset 14Jan2022, outcome "not recovered", described as "On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6- inches wide, itchy, and painful"; VACCINATION SITE MASS (non-serious) with onset 14Jan2022, outcome "not recovered", described as "On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6-inches wide, itchy, and painful"; VACCINATION SITE PRURITUS (non-serious), VACCINATION SITE PAIN (non-serious), PYREXIA (non-serious) all with onset 15Jan2022, outcome "not recovered", and all described as "By Saturday, the red area was about 6-inches wide, itchy, and painful". The events "Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body became restless.", "Nothing happened for about 12 hours, but then "my" arm started throbbing and "my" whole body became restless.", ""I" was unable to sleep Thursday night.", "On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6- inches wide, itchy, and painful.", "On Friday "I" noticed there was a red bump like a bee sting at the injection site. By Saturday, the red area was about 6-inches wide, itchy, and painful.", "By Saturday, the red area was about 6-inches wide, itchy, and painful." and ""I" also maintained a fever hovering around 100 all day" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of pain in extremity, vaccination site erythema, vaccination site mass, vaccination site pruritus, vaccination site pain and pyrexia.  Additional Information:  The patient reported that "I had my booster on Thursday, 1/13. My vaccinations were both Moderna, and I did not have any adverse reactions". The patient had no known allergies. Prior to the vaccination, the patient was not diagnosed with COVID-19. The patient did not receive any other vaccines within four weeks prior to the COVID vaccine. The events pain in extremity, vaccination site erythema, vaccination site mass, vaccination site pruritus, vaccination site pain and pyrexia, the treatment included Aleve and patient was advised to add cold compresses, use calamine lotion. Since the vaccination, the patient had not been tested for COVID-19.