Itching in eyes had gone on for 9 months now/started in the right eye and then moved to left/now in both eyes/intense itching; Patient also experienced tearing, redness, and swelling of both eyes; Patient also experienced tearing, redness, and swelling of both eyes; Patient also experienced tearing, redness, and swelling of both eyes; It had caused dermatitis in her eyelids, where she was experiencing flaking.; This spontaneous case was reported by a patient and describes the occurrence of EYE PRURITUS (Itching in eyes had gone on for 9 months now/started in the right eye and then moved to left/now in both eyes/intense itching), LACRIMATION INCREASED (Patient also experienced tearing, redness, and swelling of both eyes), OCULAR HYPERAEMIA (Patient also experienced tearing, redness, and swelling of both eyes), EYE SWELLING (Patient also experienced tearing, redness, and swelling of both eyes) and BLEPHARITIS (It had caused dermatitis in her eyelids, where she was experiencing flaking.) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 012M21B, 014M20A and 012M20A) for COVID-19 vaccination.     Patient never had COVID positive test or diagnosis.  Previously administered products included for Product used for unknown indication: Flu (Flu) on 05-Oct-2021, Shingles (Shingles) on 05-Oct-2021, Pneumonia shot (Pneumonia shot and Patient experienced some conjunctivitis like symptoms after a pneumonia shot and symptoms only lasted for a few days at that time.) on 19-Oct-2021. Past adverse reactions to the above products included Conjunctivitis with Pneumonia shot; and No adverse event with Flu and Shingles. Concurrent medical conditions included Penicillin allergy, Atopic dermatitis and Asthma. Concomitant products included MONTELUKAST, SALBUTAMOL SULFATE (ALBUTEROL SULFATE) and FLUTICASONE PROPIONATE (FLOVENT) for Asthma, FLUOCINONIDE for Atopic dermatitis, ESTROGENS CONJUGATED (PREMARIN), MULTIVITAMIN [VITAMINS NOS], COLECALCIFEROL (VITAMIN D3), MAGNESIUM, GLUCOSAMINE, METHYLSULFONYLMETHANE (GLUCOSAMINE MSM), LACTOBACILLUS ACIDOPHILUS (PROBIOTIC ACIDOPHILUS [LACTOBACILLUS ACIDOPHILUS]), DOCUSATE SODIUM, CRANBERRY [VACCINIUM MACROCARPON] and FLUTICASONE PROPIONATE (FLONASE [FLUTICASONE PROPIONATE]) for an unknown indication.   On 05-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) .5 milliliter. On 05-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .5 milliliter. On 29-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .25 milliliter. On an unknown date, the patient experienced EYE PRURITUS (Itching in eyes had gone on for 9 months now/started in the right eye and then moved to left/now in both eyes/intense itching), LACRIMATION INCREASED (Patient also experienced tearing, redness, and swelling of both eyes), OCULAR HYPERAEMIA (Patient also experienced tearing, redness, and swelling of both eyes), EYE SWELLING (Patient also experienced tearing, redness, and swelling of both eyes) and BLEPHARITIS (It had caused dermatitis in her eyelids, where she was experiencing flaking.). The patient was treated with PREDNISONE (oral) at an unspecified dose and frequency. At the time of the report, EYE PRURITUS (Itching in eyes had gone on for 9 months now/started in the right eye and then moved to left/now in both eyes/intense itching), LACRIMATION INCREASED (Patient also experienced tearing, redness, and swelling of both eyes), OCULAR HYPERAEMIA (Patient also experienced tearing, redness, and swelling of both eyes), EYE SWELLING (Patient also experienced tearing, redness, and swelling of both eyes) and BLEPHARITIS (It had caused dermatitis in her eyelids, where she was experiencing flaking.) had not resolved.            Concomitant medications reported also included Calcium citrate with magnesium and zinc, and Areds2 for eyes.  Patient received booster dose on 29-Nov-2021. Patient was experiencing eye issues after the Moderna booster and had been having issues for months. It was reported that symptoms were worsened but stable now. Patient visited Primary care physician who prescribed oral prednisone to her. The prednisone provided some relief, but when she tapered off of it, the symptoms came right back.. Patient had also seen an Allergist and an Optometrist for her symptoms and there had been no resolve to her issues yet.  It was reported that patient did not had any issues with her vision.Her doctor mentioned to her that this may be due to the vaccine.  Treatment medication also included ice packs, 4-5 different lubricant eye drops, and allergy medications.