sick; arm ached; massive headache; extremely tired; weak; the patient slept about 24-48 hours; migraine headache; This is a spontaneous report received from non-contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 59-year-old female patient received BNT162b2 (BNT162B2), on 01Jun2021 as dose 2, single (Batch/Lot number: unknown) at the age of 59 years for covid-19 immunisation. The patient's relevant medical history included: "car accident" (unspecified if ongoing); "Drug allergy" (unspecified if ongoing); "diabetes type II" (unspecified if ongoing); "hypothyroidism" (unspecified if ongoing); "hiatal hernia" (unspecified if ongoing); "depression" (unspecified if ongoing); "anxiety" (unspecified if ongoing); "tremors" (unspecified if ongoing); "penicillin allergy" (unspecified if ongoing); "GERD" (unspecified if ongoing); "hearing impairment" (unspecified if ongoing); "walker user" (unspecified if ongoing); "cane user" (unspecified if ongoing); "vitamin d low" (unspecified if ongoing); "pain in back" (unspecified if ongoing); "pain in neck" (unspecified if ongoing); "acid reflux" (unspecified if ongoing); "legs cramp" (unspecified if ongoing); "overactive bladder" (unspecified if ongoing); "inflammation" (unspecified if ongoing); "migraines" (unspecified if ongoing); "lost consciousness" (unspecified if ongoing); "does not sleep" (unspecified if ongoing); "body feels run down" (unspecified if ongoing); "Vasosin allergy" (unspecified if ongoing). Concomitant medication(s) included: PANTOPRAZOLE; BACLOFEN; PREGABALIN; BUSPIRONE; ROPINIROLE; METFORMIN; VITAMIN D3; VITAMIN B12 [CYANOCOBALAMIN]; VITAMIN C [ASCORBIC ACID]; LEVOTHYROXINE; OMEPRAZOLE; DIPHENHYDRAMINE; OXYBUTYNIN; AZELASTINE HYDROCHLORIDE; FLUTICASONE PROPIONATE; ALLOPURINOL; VITAMIN B COMPLEX; MALUS SPP.; APPLE CIDER VINEGAR; ACETAMINOPHEN. Past drug history included: Bextra, reaction(s): "bextra allergy"; Motrin, reaction(s): "bextra allergy". Vaccination history included: Bnt162b2 (Dose 1, Single), administration date: May2021, for Covid-19 immunization, reaction(s): "weak", "extremely tired", "massive headache", "Sick", "the arm ached". The following information was reported: PAIN IN EXTREMITY (non-serious) with onset Jun2021, outcome "recovered", described as "arm ached"; FATIGUE (non-serious) with onset Jun2021, outcome "recovered", described as "extremely tired"; HEADACHE (non-serious) with onset Jun2021, outcome "recovered", described as "massive headache"; MIGRAINE (non-serious) with onset Jun2021, outcome "recovered", described as "migraine headache"; ILLNESS (non-serious) with onset Jun2021, outcome "recovered", described as "sick"; HYPERSOMNIA (non-serious) with onset Jun2021, outcome "unknown", described as "the patient slept about 24-48 hours"; ASTHENIA (non-serious) with onset Jun2021, outcome "recovered", described as "weak". Therapeutic measures were taken as a result of illness, pain in extremity, headache, fatigue, asthenia, migraine. Additional information: The second dose was on 01Jun2021. After both injections, the patent became sick. Sick was further clarified as, the arm ached, had a massive headache; was extremely tired, and weak. After the second injection, the symptoms were more severe and lasted longer (lasted about 5 days). Tylenol or nothing else (not further clarified) would not help the headache. The headache felt like a migraine and regular headache combined. After the second injection, the patient slept about 24-48 hours. The patient was so weak, that it was difficulty getting out of the bed. The patient treated her symptoms with a sports drink that had electrolytes. The patient must wait 2-3 weeks after her 01Jun2021 injection (2nd Pfizer vaccine) before she receives her next Ocrevus infusion. Concomitant medication: curcuma longa (Turmeric).  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.