her arm was just very hard today this morning and very sore; it feels hard at the injection site; the temperature of her injection arm is really cold; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID: (159558). The reporter is the patient.  An 80-year-old female patient received BNT162b2 (BNT162B2), on 22May2022 as dose 4 (booster), single (Lot number: FM0173) at the age of 80 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "stents in the heart" (unspecified if ongoing); "Fast heart rate" (unspecified if ongoing); "High cholesterol" (unspecified if ongoing), notes: High Cholesterol is under control with medication; "Allergy" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: flu shot, administration date: 21Oct2021, when the patient was 79-year-old, for Immunization; BNT162b2 (DOSE 1, LOT: EN6201, ANATOMICAL LOCATION: LEFT ARM), administration date: 12Feb2021, when the patient was 78-year-old, for Covid-19 Immunization; BNT162b2 (DOSE 2, LOT: EN6199, ANATOMICAL LOCATION: LEFT ARM), administration date: 06Mar2021, when the patient was 78-year-old, for Covid-19 Immunization; BNT162b2 (DOSE 3, LOT: 30155BA, ANATOMICAL LOCATION: LEFT ARM), administration date: 22Oct2021, when the patient was 79-year-old, for Covid-19 Immunization. The following information was reported: VACCINATION SITE COLDNESS (non-serious) with onset 22May2022, outcome "recovering", described as "the temperature of her injection arm is really cold"; VACCINATION SITE REACTION (non-serious) with onset 23May2022, outcome "not recovered", described as "it feels hard at the injection site"; PAIN IN EXTREMITY (non-serious), outcome "unknown", described as "her arm was just very hard today this morning and very sore". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Caller confirmed information provided by the transferring agent, stating that what she was experiencing was different than what she had experienced with her prior vaccines. Her first and second dose were the Pfizer covid vaccine, and then she got the booster, and then she had the flu shot. Yesterday afternoon she had the second booster, she got it because she was 80 years old with 2 stents in the heart as well as on Plavix. After getting the second booster yesterday, she was fine for the first hour, but then she noticed the arm got real cold, as if someone put ice on it, she said to herself that they have got to be kidding, maybe if she goes to bed the arm will get warm, however the arm got really hard not warm. This didnot bother her last night, but this morning it was still not red. Usually with her prior vaccines, around the injection site it gets red, even with the flu shot, and all vaccines, however this second booster her arm never turned red, it was still not red today, her arm was just very hard today this morning and very sore. It has got slightly warm today compared to yesterday. Caller confirms that the side effects she was experiencing are on the same arm that she received the second booster injection in. She asks if all this was normal, and why was her arm so cold. Caller states that she was just curious, this one was so much different than her other previous vaccines.  No follow-up attempts are possible. No further information is expected.