Sore arm; Redness; Swelling; This is a spontaneous report received from a contactable reporter(s) (Nurse). The reporter is the patient.  A 73-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), in Dec2022 as dose 4 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "immunocompromised" (unspecified if ongoing); "chronic lymphocytic leukemia", start date: 2004 (unspecified if ongoing), notes: diagnosed in 2007. Concomitant medication(s) included: ACYCLOVIR [ACICLOVIR]; EVUSHELD. Vaccination history included: moderna (DOSE 1, SINGLE), administration date: 07Feb2021, for Covid-19 immunization; moderna (DOSE 2, SINGLE), administration date: 07Mar2021, for Covid-19 immunization; Moderna (DOSE 3 (BOOSTER), SINGLE), administration date: Oct2021, for Covid-19 immunization; Shingrix (DOSE 1, SINGLE), administration date: Dec2021, for Immunization; Shingrix (DOSE 2, SINGLE), administration date: Jun2022, for Immunization. The following information was reported: PAIN IN EXTREMITY (non-serious), outcome "unknown", described as "Sore arm"; ERYTHEMA (non-serious), outcome "unknown", described as "Redness"; SWELLING (non-serious), outcome "unknown". Additional information: She just had a little sore arm and some redness swelling after. She did not have any adverse reaction. Just the typical stuff. She is immunocompromised and has chronic lymphocytic leukemia (CLL). Her husband has cancer of the esophagus and gets chemo and radiation. They are both immunocompromised and don't make antibodies for vaccines because of compromised immune systems. At the cancer care center in (State name), they were giving patient's Evusheld. It was an injection given every 6 months; she believes to help immunocompromised patients make antibodies. She takes acyclovir twice a day, and she has been doing that twice a day for four years. Her specialist said to stay on the acyclovir a little while longer because it would not hurt anything. Had no fever, wasn't ill, didn't feel like she couldn't get out of bed, or anything like that after the Covid-19 vaccine. She had the Moderna Covid-19 vaccine on 07Feb2021. Got the second dose one month later on 07Mar2021 and in the summer of 2021 talked to the CDC and, they came out with an extra dose for the elderly or immune compromised, and she got that in October. A lot of people thought that was the first booster, but it wasn't. It was a half dose extra of the primary series. The most recent dose she got was the Pfizer Covid-19 vaccine in December. That one was the Pfizer vaccine for the new variants. She did okay. Went to a laboratory. She was in a study two years ago through the leukemia and oncology society. Doctors wanted to know how the CLL patients did because it took a long time for doctors to agree that the Shingrix vaccine was okay for the CLL population.  She was diagnosed with CLL in 2007, but doctors said she may have had the beginnings of it as far back as 2004. Surprised she went all the way to Jul2018 before she needed treatment for her CLL based on her biomarkers. Now, they have the non-live Shingrix vaccine, and she got the first one in Dec2021 and the second in Jun2022. So, she is actually all up to date on her vaccines. Had greater than 25k antibodies from the Pfizer omicron vaccine. She is really only calling to find out about any new Covid treatments for people like her who don't make antibodies.   The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 has been requested and will be submitted if and when received.