finger and toes went numb; heart racing; blood pressure shot up; This is a spontaneous report from a Pfizer-sponsored program COVAX US SUPPORT. This report received from a contactable consumer or other non hcp. This consumer reported for patient (daughter) that a 42-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Batch/Lot number: not reported), dose 1 via an unspecified route of administration on 11Mar2021 (Age at vaccination 42 years) as dose 1, single for covid-19 immunisation. Medical history included psoriasis, immune compromised and cardiomyopathy. Concomitant medication(s) included risankizumab rzaa (SKYRIZI [RISANKIZUMAB RZAA]) (She does not know the dose her daughter receives. She just knows it is 2 injections. On 11Mar2021, the patient experienced finger and toes went numb; heart racing and blood pressure shot up. The patient underwent lab tests and procedures which included blood pressure measurement: shot up on 11Mar2021, heart rate: racing on 11Mar2021. It was reported that reporter calling on behalf of her 42-year-old daughter who after receiving the 1st dose of the vaccine experienced "heart racing, blood pressure shot up, finger and toes went numb" would that be regarded as a severe reaction and is it a contraindication to second dose. Her daughter went to get the Pfizer COVID vaccine. She takes injections for psoriasis called Skyrizi so she was immune compromised. Caller also says when the patient was pregnant and had a daughter 15 years ago she had cardiomyopathy which was a heart condition caused by the pregnancy. When her daughter got the shot about 20 seconds after it, her heart started racing, her blood pressure shot up and her fingers and toes went numb. They got the paramedics, thank God they were at a place that had paramedics, they monitored her for while and her blood pressure came back down, the heart racing sort of was off and on a little bit but finally settled and they went home. Caller doesn't think her daughter should have the second shot because of that, the paramedic didn't say anything about that, they told her to call her family doctor, and they have not gotten back to her, she doesn't know if the family doctors don't know enough about it but she put in a second request for information with them and she still has not gotten an answer. Her daughter was supposed to get it 08Apr so they have a little time but she doesn't think her daughter should have it and she wanted to see if Pfizer has any opinions about that. She also wanted to know if that was considered an allergic reaction question, is it one of the severe allergic reactions, in the severe allergic reaction section it has heart racing but she didn't know if you had to have all of those for it to be considered severe allergic reaction. The date of her daughter's first dose was 11Mar2021. She has not had anymore issues with is since that day, it is recovered, so far she has not had any issues after that episode. She confirms it happened right after the dose so it was the same day as the first dose. The only thing she knows was her daughter got her Skyrizi shot a week or a week and a half before the vaccine but she was not sure if that was relevant. Her daughter caller her dermatologist to see if she should get the injection and they told her yes, the CDC was saying follow all your regular protocols. She was not sure about the spelling of the medication. She was guessing at how to say Skyrizi. She asks will they even answer her question or will they just say talk to your family doctor. She says it is weird no one seems to be able to give an answer, they do not say go head with the second one. No one will answer, it is like they don't want to say get it or don't get it because if something happens.". Caller wanted to know if her daughter should receive second dose of vaccine. Investigation Assessment: No. The clinical outcome of all events were recovered on 11Mar2021.  No follow-up attempts are possible; information about lot/batch number cannot be obtained.