Accelarated heart; Palpitations; Feels like inflamation on left side next to the chest; Feels general malaise; Under the armpit is swollen; Fatigue; Chills; This case was received via an unknown source (no reference has been entered for a health authority or license partner) on 16-Nov-2021 and was forwarded to Moderna on 17-Nov-2021. This spontaneous case was reported by a consumer and describes the occurrence of HEART RATE INCREASED (Accelarated heart), PALPITATIONS (Palpitations), INFLAMMATION (Feels like inflamation on left side next to the chest), MALAISE (Feels general malaise) and LYMPHADENOPATHY (Under the armpit is swollen) in a 40-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. DB5F21A and D17F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported.On 18-Oct-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 15-Nov-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 15-Nov-2021, the patient experienced LYMPHADENOPATHY (Under the armpit is swollen), FATIGUE (Fatigue) and CHILLS (Chills). On 16-Nov-2021, the patient experienced HEART RATE INCREASED (Accelarated heart), PALPITATIONS (Palpitations), INFLAMMATION (Feels like inflamation on left side next to the chest) and MALAISE (Feels general malaise). The patient was treated with IBUPROFEN (ADVIL [IBUPROFEN]) for Adverse event, at a dose of 1 dosage form. At the time of the report, HEART RATE INCREASED (Accelarated heart), PALPITATIONS (Palpitations), INFLAMMATION (Feels like inflamation on left side next to the chest), MALAISE (Feels general malaise), LYMPHADENOPATHY (Under the armpit is swollen), FATIGUE (Fatigue) and CHILLS (Chills) had not resolved. No Concomitant product use was reported.The patient received their second dose of the Moderna vaccine and now had fatigue, chills and under the armpit was swollen. The patient stated that they felt chills. On 16-Nov-2021, they felt palpitations and accelerated heart. They also felt like inflammation on left side next to the chest and felt general malaise.This case concerns a 40-year-old female patient with no relevant medical history, who experienced the unexpected events of Heart Rate Increased, Palpitations, Inflammations, Malaise, and expected events of Lymphadenopathy, Fatigue and Chills. The events occurred 1-2 days after receiving the second dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the second dose was disclosed. The events of Lymphadenopathy, Fatigue and Chills are consistent with the current understanding of the mechanism of action of the vaccine. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. This case was linked to MOD-2021-390015 (Patient Link). Sender's Comments: This case concerns a 40-year-old female patient with no relevant medical history, who experienced the unexpected events of Heart Rate Increased, Palpitations, Inflammations, Malaise, and expected events of Lymphadenopathy, Fatigue and Chills. The events occurred 1-2 days after receiving the second dose of mRNA-1273 Vaccine. The rechallenge was not applicable since only information about the second dose was disclosed. The events of Lymphadenopathy, Fatigue and Chills are consistent with the current understanding of the mechanism of action of the vaccine. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.