more positive than any of the other tests looked / experiencing a rebound since I have not had a mask off in front of another person; This spontaneous case was reported by a consumer and describes the occurrence of COVID-19 (more positive than any of the other tests looked / experiencing a rebound since I have not had a mask off in front of another person) in a 30-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. Co-suspect product included non-company product NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment. Concurrent medical conditions included Drug allergy. Concomitant products included DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, PARACETAMOL, PSEUDOEPHEDRINE HYDROCHLORIDE (DAYQUIL) for an unknown indication.   On 03-Nov-2021 at 10:00 AM, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 14-May-2022, the patient started NIRMATRELVIR, RITONAVIR (PAXLOVID) (unknown route) at an unspecified dose. In May 2022, the patient experienced COVID-19 (more positive than any of the other tests looked / experiencing a rebound since I have not had a mask off in front of another person). At the time of the report, COVID-19 (more positive than any of the other tests looked / experiencing a rebound since I have not had a mask off in front of another person) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 20-May-2022, SARS-CoV-2 test: negative (Negative) negative. tested negative 2 days after the last dose (Friday) and on Saturday as well.. On 21-May-2022, SARS-CoV-2 test: negative (Negative) negative. tested negative 2 days after the last dose (Friday) and on Saturday as well..         Patient took paxlovid from Saturday 5/14/22 through Wednesday 5/18/22. Her symptoms never felt that bad to begin with and didn't seem to change much while on paxlovid. She tested negative two days after the last dose (Friday) and on Saturday as well.   On Sunday patient felt a little tickle in her throat and tested again. It was far more positive than any of the other tests looked. She didn't feel much worse, but was experiencing a rebound of COVID-19 since she had not had a mask off in front of another person since the 14th. She was not sure about the symptoms when to get recover. The device Date was : 23May2022  Company comment: This spontaneous case concerns a 30-year-old, female patient with no reported medical history who experienced the unexpected, non-serious adverse event of special interest of COVID-19, which occurred approximately 6 months after receiving the third dose of mRNA-1273 vaccine. Patient contracted  COVID-19 and was prescribed with Nirmatrelvir, Ritonavir (Paxlovid) at unknown dose and frequency. She took the medication for 4 days. Two days after completing the Paxlovid regimen she tested negative on two consecutive occasions (05/20/22 and 05/21/22). Subsequently the following day the patient felt a tickle in her throat and decided to test again, this time she tested positive for COVID-19. Further details on other diagnostic or laboratory test done were not provided in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a 30-year-old, female patient with no reported medical history who experienced the unexpected, non-serious adverse event of special interest of COVID-19, which occurred approximately 6 months after receiving the third dose of mRNA-1273 vaccine. Patient contracted  COVID-19 and was prescribed with Nirmatrelvir, Ritonavir (Paxlovid) at unknown dose and frequency. She took the medication for 4 days. Two days after completing the Paxlovid regimen she tested negative on two consecutive occasions (05/20/22 and 05/21/22). Subsequently the following day the patient felt a tickle in her throat and decided to test again, this time she tested positive for COVID-19. Further details on other diagnostic or laboratory test done were not provided in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.