May be a side effects too with Bosulif mixed with Covid-19; he took the Pfizer Covid vaccine, the two shot, he got no antibodies; May be a side effects too with Bosulif mixed with Covid-19; he took the Pfizer Covid vaccine, the two shot, he got no antibodies; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program.  A 78 year-old male patient received bnt162b2 (BNT162B2), intramuscular, administered in arm left, administration date 09Apr2021 (Lot number: ER8729) at the age of 78 years as dose 2, single for covid-19 immunisation; bosutinib (BOSULIF) (ongoing) (Batch/Lot number: unknown) at unk, 1x/day. Relevant medical history included: "CML Leukemia", start date: 14Jul2001 (ongoing), notes: Verbatim: CML Leukemia; "Heart issues" (unspecified if ongoing), notes: Verbatim: Heart issues; "Blood pressure" (ongoing), notes: Verbatim: Blood pressure; "Cholesterol" (unspecified if ongoing); "Heart attack", start date: 19Jul2019 (unspecified if ongoing); "Heart stents", start date: 15Jan2021 (ongoing), notes: 2 stents and angiop; "Macular degeneration", start date: 2016 (ongoing), notes: Started in left eye, both eyes now; "Anemia" (ongoing). Concomitant medication(s) included: AMLODIPINE taken for blood pressure measurement (ongoing); CLONIDINE taken for blood pressure abnormal (ongoing); IRBESARTAN taken for blood pressure abnormal (ongoing); CLOPIDOGREL; ASPIRIN; ATORVASTATIN taken for blood cholesterol; IRON taken for anaemia (ongoing). Vaccination history included: Bnt162b2 (Dose: 1st, LOT# (first shot): EP6955, Anatomical site of injection: Left arm), administration date: 19Mar2021, when the patient was 78 years old, for Covid-19 immunization. The following information was reported: DRUG INTERACTION (non-serious), VACCINE INDUCED ANTIBODY ABSENT (non-serious), outcome "unknown" and all described as "May be a side effects too with Bosulif mixed with Covid-19; he took the Pfizer Covid vaccine, the two shot, he got no antibodies". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Patient's wife reported in regards to may be a side effects to the Bosulif medication mixed with Covid-19. She has little bit more information, they ran the antibody test for the patient that has leukemia and he was taking Bosulif. She said something about antibody is not coming back or something like that. She does has more information in, some concern regarding. On paraphrasing the concern: Reporter stated that, she wanted to report fact that when her husband took the Pfizer Covid vaccine, the two shot, he got no antibodies, reporter just wanted Pfizer to know that, so patient had to get another shot or series of shot. Reporter stated, when requested to probe further as yes sure, it will help because that way may be they can develop a protocol or something to tell people to take or have leukemia that might not work for them. Reporter didn't expect them to call me back. There wasn't any side effects, it's just that 16Aug2021 test was done and he had no antibodies for Covid. Reporter stated, He took it from where he got the vaccine. The patient takes Bosulif from Pfizer and he takes different medication for blood pressure. He had lab work done on yesterday, September 16, His oncologist ran blood work to check his PCR levels for leukemia. Reporter stated, No for treatment, the Doctor, that was their primary doctor on August 16 and he said let me see with oncologist confirm that it's ok if he get the another shot. That's all they did yesterday. The oncologist Doctor said go ahead and get another shot to avoid getting back the Covid. Prior vaccination (within 4 weeks): None. The patient had Heart attack on 19Jul2019 at 10:00 PM with Hospitalization/ prolongation of hosp. for 6 days. AE required visit to Emergency room and recovered with sequelae on 15Jan2021. Treatment was provided and new medication Blood thinners, cholesterol med were started. The patient had Stents, heart on 15Jan2021, hospitalized for 2 days and recovered. Treatment: initiation of new medication/ other treatment/ procedure was done. Pfizer has been excellent to us through Pfizer together. The doctor was concerned that no antibodies had been created and suggested it might be due to CML or Bosulif. This was reported only for information, since both medication are developed by Pfizer. The patient took a 3rd vaccination on 17Sep2021 and will definitely continue the Bosulif.   No follow-up attempts are possible. No further information is expected.