Fever blisters in the lip; "I thought my head was going to blow up"; "Couldn't even walk a mile"; Diarrhea; Face were really swollen/swell up so bad; Hands were really swollen/swell up so bad; Spasms in the stomach; Back of my head neck were so sore; Itchy small rash; Upper part was so sore; Every joint hurt; Headache was so bad/really bad headache/ headache got worse in the back of my head; Fever was up and down all day/100° fever/slight fever; Bad chills; Exhaustion/ totally exhausted/ was very tired; Achy all over; Sore arm; This spontaneous case was reported by a consumer and describes the occurrence of SWELLING FACE (Face were really swollen/swell up so bad), PERIPHERAL SWELLING (Hands were really swollen/swell up so bad), ABDOMINAL PAIN UPPER (Spasms in the stomach), NECK PAIN (Back of my head neck were so sore) and PAIN IN EXTREMITY (Sore arm) in a 69-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 046B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 25-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 25-Apr-2021, the patient experienced PAIN IN EXTREMITY (Sore arm). On 26-Apr-2021, the patient experienced SWELLING FACE (Face were really swollen/swell up so bad), PERIPHERAL SWELLING (Hands were really swollen/swell up so bad), ABDOMINAL PAIN UPPER (Spasms in the stomach), NECK PAIN (Back of my head neck were so sore), DIARRHOEA (Diarrhea), RASH PRURITIC (Itchy small rash), PAIN (Upper part was so sore), ARTHRALGIA (Every joint hurt), HEADACHE (Headache was so bad/really bad headache/ headache got worse in the back of my head), PYREXIA (Fever was up and down all day/100° fever/slight fever), CHILLS (Bad chills), FATIGUE (Exhaustion/ totally exhausted/ was very tired) and MYALGIA (Achy all over). On 01-May-2021, the patient experienced GAIT DISTURBANCE ("Couldn't even walk a mile"), LIP BLISTER (Fever blisters in the lip) and FEELING ABNORMAL ("I thought my head was going to blow up"). The patient was treated with PARACETAMOL (TYLENOL) for Adverse event, at an unspecified dose and frequency. At the time of the report, SWELLING FACE (Face were really swollen/swell up so bad), PERIPHERAL SWELLING (Hands were really swollen/swell up so bad), ABDOMINAL PAIN UPPER (Spasms in the stomach), NECK PAIN (Back of my head neck were so sore), PAIN IN EXTREMITY (Sore arm), GAIT DISTURBANCE ("Couldn't even walk a mile"), DIARRHOEA (Diarrhea), LIP BLISTER (Fever blisters in the lip), FEELING ABNORMAL ("I thought my head was going to blow up"), RASH PRURITIC (Itchy small rash), PAIN (Upper part was so sore), ARTHRALGIA (Every joint hurt), HEADACHE (Headache was so bad/really bad headache/ headache got worse in the back of my head), PYREXIA (Fever was up and down all day/100° fever/slight fever), CHILLS (Bad chills), FATIGUE (Exhaustion/ totally exhausted/ was very tired) and MYALGIA (Achy all over) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 26-Apr-2021, Body temperature: 100 (High) 100°.   No relevant concomitant medications was reported.   This case was linked to MOD-2021-356638 (Patient Link).