A/G Ratio 2.3; autoimmune hepatitis; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 65-year-old male patient received BNT162b2 (BNT162B2), on 12May2021 as dose 1, single (Lot number: EW0177) at the age of 64 years, in arm for covid-19 immunization. The patient's relevant medical history included: "Right knee" (unspecified if ongoing), notes: surgery, Feb2020; "Left knee" (unspecified if ongoing), notes: surgery, Jul2020; "Haglund's deformity (Achilles heel)" (unspecified if ongoing), notes: surgery, Apr2018. The patient's concomitant medications were not reported. The following information was reported: AUTOIMMUNE HEPATITIS (medically significant),on Jul2021, outcome "not recovered",AE required visit to Physician office; LABORATORY TEST ABNORMAL (non-serious), outcome "not recovered", described as "A/G Ratio 2.3". The patient underwent the following laboratory tests and procedures: Alanine aminotransferase increased: (unspecified date) 180 IU/l, notes: High; (28May2021) 18 IU/l; Albumin globulin ratio: (unspecified date) 2.2; (28May2021) 2.3; Antibody test: (22Jan2022) 44, notes: High; Antinuclear antibody: (22Jan2022) Negative; Aspartate aminotransferase increased: (unspecified date) 134 IU/l, notes: High; (28May2021) 23 IU/l; Basophil count: (28May2021) 0 %; (03Jan2022) 1 %; Blood albumin: (unspecified date) 4.4 g/dl; (28May2021) 4.1 g/dl; Blood alkaline phosphatase: (unspecified date) 105 IU/l; (28May2021) 83 IU/l; Blood bilirubin: (unspecified date) 0.8 mg/dl; (28May2021) 0.6 mg/dl; Blood calcium: (unspecified date) 9.6 mg/dl; (28May2021) 9.3 mg/dl; Blood chloride: (28May2021) 104 mmol/L; (03Jan2022) 104 mmol/L; Blood creatinine: (28May2021) 0.94 mg/dl; (03Jan2022) 0.94 mg/dl; Blood glucose: (28May2021) 97 mg/dl; (03Jan2022) 90 mg/dl; Blood iron: (22Jan2022) 119 ug/dL; Blood lactate dehydrogenase: (unspecified date) 214 IU/l; Blood magnesium: (unspecified date) 2.0 mg/dl; Blood parathyroid hormone: (unspecified date) 21 pg/mL, notes: Reference Interval: 15-65; Blood phosphorus decreased: (unspecified date) 2.7 mg/dl, notes: Low; Blood potassium: (28May2021) 4.7 mmol/L; (03Jan2022) 5.1 mmol/L; Blood sodium: (28May2021) 141 mmol/L; (03Jan2022) 142 mmol/L; Blood test: (30Dec2021) Unknown Results, notes: AST- 134; (30Dec2021) Unknown Results, notes: ALT- 180; Blood thyroid stimulating hormone: (unspecified date) 1.960 uiU/mL; (28May2021) 2.33 uiU/mL; Blood urea: (28May2021) 13 mg/dl; (03Jan2022) 12 mg/dl; Blood urea nitrogen/creatinine ratio: (28May2021) 13; (03Jan2022) 14; Calcium ionized: (unspecified date) 5.0 mg/dl; Carbon dioxide: (28May2021) 24 mmol/L; (03Jan2022) 24 mmol/L; Ceruloplasmin: (22Jan2022) 22.1 mg/dl; C-reactive protein: (unspecified date mg/l; () 221Dec2020) 3 mg/l; EGFR status assay: (28May2021) 98 mL/min/1.73; (03Jan2022) 99 mL/min/1.73; (28May2021) 85 mL/min/1.73; (03Jan2022) 85 mL/min/1.73; Eosinophil count: (28May2021) 3 %; (03Jan2022) 3 %; Globulin: (unspecified date) 2.0 g/dl; (28May2021) 1.8 g/dl; Hematocrit: (28May2021) 38.7 %; (03Jan2022) 46.3 %; Hemoglobin: (28May2021) 13.4 g/dl; (03Jan2022) 15.7 g/dl; Hepatitis A antibody: (22Jan2022) Negative; Hepatitis B core antibody negative: (22Jan2022) Negative; Hepatitis B surface antigen: (22Jan2022) Negative; Hepatitis C antibody: (22Jan2022) <0.1 s/co ratio; Immature granulocyte count: (28May2021) 0 %; (03Jan2022) 0 %; Iron binding capacity total: (22Jan2022) 343 ug/dL; Iron binding capacity unsaturated: (22Jan2022) 224 ug/dL; liver panel test: (20Jan2022) Unknown Results, notes: Actin antibody (smooth muscle)-44; Lymphocyte count: (28May2021) 20 %; (03Jan2022) 24 %; Mean cell hemoglobin: (28May2021) 31.1 pg; (03Jan2022) 31.5 pg; Mean cell hemoglobin concentration: (28May2021) 34.6 g/dl; (03Jan2022) 33.9 g/dl; Mean cell volume: (28May2021) 91 fL; (03Jan2022) 92 fL; Monocyte count: (28May2021) 8 %; (03Jan2022) 8 %; Neutrophil count: (28May2021) 65 %; (03Jan2022) 68 %; Platelet count: (28May2021) 200  x10E3/uL; (03Jan2022) 182 x10E3/uL; Protein total: (unspecified date) 6.4 g/dl; (28May2021) 5.9 g/dl; Red blood cell count: (28May2021) 4.26 x10E6/uL; (03Jan2022) 5.05 x10E6/uL; Red blood cell sedimentation rate: (unspecified date) 7 mm/hr; (21Dec2020) 29 mm/hr; Red cell distribution width: (28May2021) 14.5 %; (03Jan2022) 14.9 %; Thyroxine: (unspecified date) 1.17 ng/dL; (21Dec2020) 0.94 ng/dL; Transferrin saturation: (22Jan2022) 35 %; White blood cell count: (28May2021) 5.8 x10E3/uL; (03Jan2022) 5.1 x10E3/uL. Therapeutic measures were taken as a result of autoimmune hepatitis, laboratory test abnormal.