Having difficulty breathing; wheezing, took 40mg of prednisone and still wheezing went to doctor and had to get steroid shot to breath and taking nebulizers; Not diabetic and blood sugar keeps dropping into 40s; Have asthma so have emergency steroids on hand; Inappropriate dose of Vaccine administered; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 43-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 20Jul2022 at 14:15 as dose 5 (booster), single (Batch/Lot number: unknown) at the age of 43 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Common variable Immune deficiency" (unspecified if ongoing); "Natural Killer Cell Deficiency" (unspecified if ongoing); "Asthma" (unspecified if ongoing); "Hyper Ige syndrome" (unspecified if ongoing); "Migraines" (unspecified if ongoing); "Seizures" (unspecified if ongoing). Concomitant medication(s) included: VIMPAT; ATENOLOL; EFFEXOR XL; TOPAMAX. Past drug history included: Compazine, reaction(s): "Known allergies: Compazine"; Codeine, reaction(s): "Known allergies: Codeine"; Amoxicillin for Known allergies: Amoxicillin; Imodium, reaction(s): "Known allergies: Imodium"; Cipro, reaction(s): "Known allergies: Cipro". Vaccination history included: Covid-19 vaccine (Primary immunization series completed but manufacture unknown.), for COVID-19 Immunization; Covid-19 vaccine (DOSE 3 (BOOSTER), SINGLE), for COVID-19 Immunization; Covid-19 vaccine (DOSE 4 (BOOSTER), SINGLE), for COVID-19 Immunization. The following information was reported: INCORRECT DOSE ADMINISTERED (non-serious) with onset 20Jul2022, outcome "unknown", described as "Inappropriate dose of Vaccine administered"; ASTHMA (life threatening) with onset 21Jul2022 at 08:00, outcome "recovering", described as "Have asthma so have emergency steroids on hand"; DYSPNOEA (life threatening) with onset 21Jul2022 at 08:00, outcome "recovering", described as "Having difficulty breathing"; BLOOD GLUCOSE DECREASED (life threatening) with onset 21Jul2022 at 08:00, outcome "recovering", described as "Not diabetic and blood sugar keeps dropping into 40s"; WHEEZING (life threatening) with onset 21Jul2022 at 08:00, outcome "recovering", described as "wheezing, took 40mg of prednisone and still wheezing went to doctor and had to get steroid shot to breath and taking nebulizers". The events "having difficulty breathing", "wheezing, took 40mg of prednisone and still wheezing went to doctor and had to get steroid shot to breath and taking nebulizers", "not diabetic and blood sugar keeps dropping into 40s" and "have asthma so have emergency steroids on hand" required physician office visit. The patient underwent the following laboratory tests and procedures: Blood glucose: dropping into 40s, notes: Not diabetic and blood sugar keeps dropping into 40s. Therapeutic measures were taken as a result of dyspnoea, wheezing, blood glucose decreased, asthma.  Clinical course: The patient took 40mg of prednisone and still wheezing went to doctor and had to get steroid shot to breath and taking nebulizers. Also, not diabetic and blood sugar keeps dropping into 40s and taking hours to get it up. Have taking hours to get it up. Have asthma so have emergency steroids on hand. No other vaccine administered in four weeks. No covid Prior vaccination. If covid tested post vaccination: No  The information on the batch/lot number for [BNT162B2] has been requested and will be submitted if and when received.