rash/rash that traveled over whole body; hives spread all over her body; Covid arm after the second dose; could be an allergic reaction to the vaccine or her immune system not doing well with the vaccine; really itchy; big yellow like blisters on her thighs; exfoliating/skin was flaking off; immune system not doing well with the vaccine; This is a spontaneous report received from contactable reporter (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 66 year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), administration date 01Aug2021 (Batch/Lot number: unknown) at the age of 66 years as dose 2, single for COVID-19 immunisation. Relevant medical history included: "Hashimoto's disease" (ongoing), notes: she has had this since she was about 25 years old. Concomitant medication included: SYNTHROID taken for autoimmune thyroiditis (ongoing). Past drug history included: Codeine, reactions: "spins"; Codeine, reaction(s): "vomiting"; Propofol, reaction(s): "super runny nose". Vaccination history included: Bnt162b2 (first dose; Lot Number: EW0181), administration date: 09Jul2021, when the patient was 66 years old, for Covid-19 immunization, reactions: "COVID arm", "hives ", "itchiness". The following information was reported: RASH (non-serious) with onset Aug2021, outcome "recovered" (2021), described as "rash/rash that traveled over whole body"; URTICARIA (non-serious) with onset Aug2021, outcome "recovered" (2021), described as "hives spread all over her body"; LIMB DISCOMFORT (non-serious) with onset Aug2021, outcome "unknown", described as "Covid arm after the second dose"; HYPERSENSITIVITY (non-serious) with onset Aug2021, outcome "unknown", described as "could be an allergic reaction to the vaccine or her immune system not doing well with the vaccine"; PRURITUS (non-serious) with onset Aug2021, outcome "recovering", described as "really itchy"; BLISTER (non-serious) with onset Aug2021, outcome "recovering", described as "big yellow like blisters on her thighs"; SKIN EXFOLIATION (non-serious) with onset Aug2021, outcome "unknown", described as "exfoliating/skin was flaking off"; IMMUNE SYSTEM DISORDER (non-serious), with onset Aug2021, outcome "unknown", described as "immune system not doing well with the vaccine". The events "rash/rash that traveled over whole body", "hives spread all over her body", "covid arm after the second dose", "could be an allergic reaction to the vaccine or her immune system not doing well with the vaccine", "really itchy", "big yellow like blisters on her thighs", "exfoliating/skin was flaking off" and "immune system not doing well with the vaccine" were evaluated at the physician office visit. Therapeutic measures were taken as a result of urticaria.   Additional information: The patient what she thought was hives spread all over her body and lasted for 2 months. She stated that her doctor does not want her to receive a booster dose but her family wanted her to receive one. She would like to know any information regarding someone having that reaction and then receiving the booster dose. Her doctor said that the reaction she had after the second dose was not considered hives because if they were hives it would only last two days. She states that the reaction started in her left arm and spots were different than other. She had big yellow like blisters on her thighs and it also went down her spine, butt crack and ankles. She asked if a rash all over the body is considered a severe allergic reaction since she did not experience anaphylactic shock. She stated that her doctor sent her to an allergist and the allergist said they don't know what was going on and because they do not know all the ingredients in the vaccine. She would like to know if their is any special ingredients in the vaccine and if she can have the list of the ingredients in the vaccine. He told her they could be an allergic reaction to the vaccine or her immune system not doing well with the vaccine. She also had COVID arm after the second dose on an unspecified date in Aug2021. She stated that also after the second dose she broke out into hives, or what she thought were hives.  She said that over a period of weeks or a month they spread all over her body, to her ankles, down her spine, to her butt and stated they were really itchy. The patient stated that these hives lasted for 2 months. She didn't take anything for them because she is sensitive to medications and that all she used was Calamine Plus lotion. The second dose the caller wasn't as tired but the hives on the arm started traveling. They were hives that went from the base of the caller's neck, to her butt crack, on her legs and arms and that stayed for 2 months. Then the caller got blisters on her legs. The patient's doctors said this reaction was too bad to get the booster dose. They all concurred that she should not get another dose. Her dermatologist and allergist said she cannot have the booster. It is not that she did not require it. She wanted to get it. The blisters are not in all of them, just the ones on her thigh. She also wanted to add the allergists said she was exfoliating and her skin was flaking off on an unspecified date in Aug2021.    The lot number for bnt162b2 was not provided and will be requested during follow up.