multiple immunosuppressed issues; dry, choking cough which has gotten worse; soreness all over which is increasingly getting worse; shortness of breath worsening for the past month; Pulmonary Embolism; multiple blood clots in both lungs; severe muscles issues - soreness all over which is increasingly getting worse; This spontaneous case was reported by a consumer and describes the occurrence of PULMONARY EMBOLISM (Pulmonary Embolism), IMMUNOSUPPRESSION (multiple immunosuppressed issues), THROMBOSIS (multiple blood clots in both lungs), MUSCLE DISCOMFORT (severe muscles issues - soreness all over which is increasingly getting worse), DYSPNOEA (shortness of breath worsening for the past month), COUGH (dry, choking cough which has gotten worse) and MYALGIA (soreness all over which is increasingly getting worse) in a 73-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Cardiac disorder NOS.   On 20-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 09-Apr-2021, the patient experienced PULMONARY EMBOLISM (Pulmonary Embolism) (seriousness criteria hospitalization and medically significant) and THROMBOSIS (multiple blood clots in both lungs) (seriousness criteria hospitalization and medically significant). In April 2021, the patient experienced MUSCLE DISCOMFORT (severe muscles issues - soreness all over which is increasingly getting worse) (seriousness criterion hospitalization). On an unknown date, the patient experienced IMMUNOSUPPRESSION (multiple immunosuppressed issues) (seriousness criteria hospitalization and medically significant), DYSPNOEA (shortness of breath worsening for the past month) (seriousness criterion hospitalization), COUGH (dry, choking cough which has gotten worse) (seriousness criterion hospitalization) and MYALGIA (soreness all over which is increasingly getting worse) (seriousness criterion hospitalization). The patient was hospitalized from 09-Apr-2021 to 13-Apr-2021 due to DYSPNOEA, PULMONARY EMBOLISM and THROMBOSIS, and then for 5 days until 13-Apr-2021 due to MUSCLE DISCOMFORT. On 13-Apr-2021, THROMBOSIS (multiple blood clots in both lungs) had resolved. At the time of the report, PULMONARY EMBOLISM (Pulmonary Embolism), IMMUNOSUPPRESSION (multiple immunosuppressed issues), MUSCLE DISCOMFORT (severe muscles issues - soreness all over which is increasingly getting worse), DYSPNOEA (shortness of breath worsening for the past month), COUGH (dry, choking cough which has gotten worse) and MYALGIA (soreness all over which is increasingly getting worse) outcome was unknown.            No concomitant medication information was mentioned by reporter  No treatment medication information was mentioned by reporter  Company Comment:Based on medical history of cardiovascular disease, and the time frame between the vaccine administration and the occurrence of  the events are assessed as unlikely related to mRNA-1273. Patient's advance age may also be a contributor.; Sender's Comments: Based on medical history of cardiovascular disease, and the time frame between the vaccine administration and the occurrence of  the events are assessed as unlikely related to mRNA-1273. Patient's advance age may also be a contributor.