Patient was hospitalized because of Meningitis after getting the first booster; Symptoms of meningitis have worsened; This spontaneous case was reported by a patient and describes the occurrence of MENINGITIS (Patient was hospitalized because of Meningitis after getting the first booster) and CONDITION AGGRAVATED (Symptoms of meningitis have worsened) in a 62-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 048F21A, 002A2 and 007M20A) for COVID-19 prophylaxis.     Concurrent medical conditions included Penicillin allergy and Meningitis (She had the condition for 15 years.) since 2007.   On 27-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Nov-2021, the patient experienced MENINGITIS (Patient was hospitalized because of Meningitis after getting the first booster) (seriousness criteria hospitalization and medically significant) and CONDITION AGGRAVATED (Symptoms of meningitis have worsened) (seriousness criterion hospitalization). At the time of the report, MENINGITIS (Patient was hospitalized because of Meningitis after getting the first booster) and CONDITION AGGRAVATED (Symptoms of meningitis have worsened) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant and treatment medications were reported.   Patient was never tested positive for Covid. Patient mentioned that meningitis has worsenend since she got the Moderna vaccine. No other vaccine was given to the patient prior to getting the Moderna vaccine. Patient was hospitalized because of meningitis after getting the first booster in last November 2021. Patient didnt experienced a similar event in the past. Symptoms of meningitis have worsened.  Company Comment: This spontaneous case concerns a 62-years-old female patient, with medical history of Meningitis (she had the condition for 15 years, since 2007)  who experienced the unexpected seriousness criteria hospitalization and medically significant AESI of meningitis and the seriousness criteria medically significant  event of condition aggravated  the same day after  3rd. dose of  mRNA-1273 vaccine. At the time of the report, the event had not resolved. The medical history of meningitis is a confounder for the events. The benefit-risk relationship of mrna-1273 is not affected by this report. Events seriousness was assessed based on medical judgement.   This case was linked to MOD-2022-644015 (Patient Link).; Sender's Comments: Company Comment: This spontaneous case concerns a 62-years-old female patient, with medical history of Meningitis (she had the condition for 15 years, since 2007)  who experienced the unexpected seriousness criteria hospitalization and medically significant AESI of meningitis and the seriousness criteria hospitalization event of condition aggravated  the same day after  3rd. dose of  mRNA-1273 vaccine. At the time of the report, the event had not resolved. The medical history of meningitis is a confounder for the events. The benefit-risk relationship of mrna-1273 is not affected by this report. Events seriousness was assessed based on medical judgement.