severe chills; shaking uncontrollably; nausea/extremely nauseous; malaise; fatigue; She has a lot of difficulties; couldn't eat or drink for 2 days; several chronic, illnesses; This is a spontaneous report from a contactable Physician (parent). This Physician reported for a 23-year-old female patient that:  A 23-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; formulation: Solution for injection, Lot number and Expiry date was not reported), dose 1 via an unspecified route of administration on an unspecified date as DOSE 1, SINGLE for covid-19 immunisation. Medical history included autoimmune disorder, inflammation, pancreatitis, colitis, underweight, lyme disease, from an unknown date and unknown if ongoing. Concomitant medications included ibuprofen (ADVIL [IBUPROFEN]) taken for an unspecified indication, start and stop date were not reported; hydroxychloroquine sulfate (PLAQUENIL [HYDROXYCHLOROQUINE SULFATE]) taken for autoimmune disorder, start and stop date were not reported; paracetamol (TYLENOL) taken for an unspecified indication, start and stop date were not reported; ondansetron hydrochloride (ZOFRAN [ONDANSETRON HYDROCHLORIDE]) taken for an unspecified indication, start and stop date were not reported. Asking that what is the risk for the second, on the trial with 12-15 years old. is the dosage the same, will the dosage be different, she is so thin, its all relevant, asking what causes the shaking response, DSU response: Everyone said that they had the chills and shaking. sometimes the shaking would start 8 hours later. Asking should she get the second shot; 3 weeks is this Sunday; she weighs 83 to 84 pounds; body type is like a 16-year-old. She is just gotten out of inflammatory problem from a response of treatment for lime disease, just had pancreatitis, colitis, that she recovered from. All prior to vaccination. on Immunosuppressant medications. Plaquenil. The second shot is going to trigger some inflammatory response, that are not already in motion with her body, her body just started attacking her. Asked her doctor, friends that are doctors, they don't know what to do. She takes Advil, Tylenol and Zofran. Asking will the dosage be different; she is so thin. It's all relevant. Response: Several people have had wave of chill and a shake started after the second shot and lasted 10 minutes. Didn't report, because this was part of what could occur. One of the nurses, had that administered the vaccine said she also had the chills, had a mild allergic response, with cheeks were beat red, ears were red, and aware of them. : Second dose of Pfizer covid vaccine- took Benadryl before the vaccine, doctor told to do that. Had fatigue after first and second shot. I was sitting in waiting area, within 15 minutes, I was shaking, but very mild, my daughter was bouncing in her seat, it was profuse, it lasted with her a half an hour. Meeting with immunologist on Wednesday for daughter. : The talk around here, is that you will get the shakes after the vaccine, her nurse that gave her shot had the chills 6 hours later. My nephew got it 8 hours later. Asking How long does the first dose lasts for, the message isn't out there to report all side effects, that information isn't clear, thought it was an expected minimal response and didn't think it should be reported. It would be best to let everyone know that you would like all side effects reported for collection of safety data. She was 23-year-old; she weighs 83 pounds and has autoimmune problems; she received her first Pfizer shot. On an unspecified date she had severe chills, shaking uncontrollably, nausea, went to ER shaking stopped after half an hour, extremely nauseous, they gave her Zofran, went home and was extremely nauseous, couldn't eat or drink for 2 days. She didn't really take her medications, end of 2nd night, she took Zofran, and she could eat after that, 3rd day started recovering, and she slept, and had malaise, fatigue, nausea. She has a lot of difficulties, No one has had that on the first shot, she's had such a strong response on the first shot. She has several chronic, illnesses, she stands in a spot on her own, it is unique situation. The patient underwent lab tests and procedures which included weight: 83 to 84 lbs on an unspecified date. The patient visits emergency room for the events severe chills, shaking uncontrollably, nausea. Treatment received for the events. Outcome of the event shaking uncontrollably was recovered on an unspecified date in 2021 and rest of the events was recovering.   No follow-up attempts are possible; information about lot/batch number cannot be obtained.