The next morning I attempted to log into work. I experienced brain fog where I could not recall basic words to form sentences, I was unable to write an email due to the numbness with my fingers, the brain fog; I experienced brainfog where I could not recall basic words to form sentences; I could not recall the names of coworkers with whom I communicate daily, to add to the receive the email; I was unable to write an email due to the numbness with my fingers, the brainfog, and blurriness in my eyes; I was unable to write an email due to the numbness with my fingers, the brainfog, and blurriness in my eyes; 5-10 min into the drive, my entire left arm went numb, through my wrist and fingers.  By the time I got home (about a 15 min drive) two fingers on my right hand hand went numb, my right thigh was numb. Then my cheeks and lips were numb.; Lips were numb; This is a spontaneous report received from contactable reporter (Consumer or other non-HCP). The reporter is the patient.   A 49-year-old female patient (not pregnant) received BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE), administered in left arm, administration date 23Nov2021 at 18:30 (Lot number: FG3527) at the age of 49 years as dose 2, single for COVID-19 immunisation. Relevant medical history included: "Single functional kidney" (unspecified if ongoing), notes: One functioning kidney. There were no concomitant medications. Vaccination history included: BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, DOSE 1, SINGLE, Lot Number: FG3527, Anatomical location: Left arm, Administration time: 18:30, Route of administration: unspecified), administration date: 02Nov2021, when the patient was 49 years old, for COVID-19 immunisation.  The following information was reported: HYPOAESTHESIA (non-serious) with onset 23Nov2021 at 18:45, outcome "recovered with sequelae" (unknown date in Nov2021), described as "5-10 min into the drive, my entire left arm went numb, through my wrist and fingers. By the time I got home (about a 15 min drive) two fingers on my right hand hand went numb, my right thigh was numb. Then my cheeks and lips were numb"; HYPOAESTHESIA ORAL (non-serious), with onset 23Nov2021, outcome "recovered with sequelae" (unknown date in Nov2021), and all described as "Lips were numb"; FEELING ABNORMAL (non-serious), APHASIA (non-serious), DYSGRAPHIA (non-serious), VISION BLURRED (non-serious), all with onset 24Nov2021, outcome "recovered with sequelae" (an unknown date in Nov2021), and all described as "The next morning the patient attempted to log into work. She experienced brain fog where she could not recall basic words to form sentences, she was unable to write an email due to the numbness with her fingers, the brain fog, and blurriness in her eyes. The patient could not recall the names of coworkers with whom she communicated daily, to add to the receive the email". Therapeutic measures were not taken as a result of hypoaesthesia, hypoaesthesia oral, feeling abnormal, aphasia, dysgraphia and vision blurred.  Additional Information: The patient had no known allergies. The patient did not receive any other vaccines within four weeks prior to COVID vaccine. Prior to vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient had not been tested for COVID-19. The patient waited for 15 min after the 2nd dose, to determine dizziness. The events did not result in doctor or other healthcare professional office/clinic visit, and emergency room/department or urgent care.