Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF"; Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF"; He was diagnosed with an advanced prostate cancer on September2021; This spontaneous case was reported by a consumer and describes the occurrence of PROSTATE CANCER (He was diagnosed with an advanced prostate cancer on September2021), ENTERITIS (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") and CLOSTRIDIUM DIFFICILE INFECTION (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Immunocompromised.   In April 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In April 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In September 2021, the patient experienced PROSTATE CANCER (He was diagnosed with an advanced prostate cancer on September2021) (seriousness criterion medically significant). On an unknown date, the patient experienced ENTERITIS (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") (seriousness criterion hospitalization prolonged) and CLOSTRIDIUM DIFFICILE INFECTION (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") (seriousness criteria hospitalization prolonged and medically significant). The patient was hospitalized from 18-Oct-2021 to 18-Nov-2021 due to CLOSTRIDIUM DIFFICILE INFECTION and ENTERITIS. At the time of the report, PROSTATE CANCER (He was diagnosed with an advanced prostate cancer on September2021), ENTERITIS (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") and CLOSTRIDIUM DIFFICILE INFECTION (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered PROSTATE CANCER (He was diagnosed with an advanced prostate cancer on September2021) and CLOSTRIDIUM DIFFICILE INFECTION (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF") to be not related. No further causality assessment was provided for ENTERITIS (Caller mentioned that from 18October2021 until 18November2021, the patient was hospitalized for a month  he had a reaction to something that gave him enteritis and "CDIF").    No Concomitant informations were reported.  No Treatment informations were reported  Patient is Immunocompromised, Patient has not started chemotherapy yet.  Company comment included This is a spontaneous case concerning a male patient of unknown age, with no reported medical history, who experienced the serious (due to hospitalization) unexpected, according, events of Clostridium difficile infection and enteritis and the serious (due to important medical condition) unexpected, according CCDS, event of Prostate cancer. The event Prostate cancer occurred approximately 5 months after the second dose of mRNA-1273 vaccine, exact date of vaccination and event is not provided. The events of Clostridium difficile infection and enteritis occurred on an unknown date after the second dose of mRNA-1273 vaccine. The rechallenge was not applicable due to the nature of the event Prostate cancer and for the events Clostridium difficile infection and enteritis the rechallenge was not applicable since the events outcome was unknown. The events of Clostridium difficile infection and enteritis were considered unrelated to the vaccine per the reporter's assessment. The patient was hospitalized for a month, the outcome of the events and treatments received were not provided. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.  Caller stated that (enteritis and CDIF) this is not related to the vaccine.   This case was linked to MOD-2021-403802 (Patient Link).; Sender's Comments: This is a spontaneous case concerning a male patient of unknown age, with no reported medical history, who experienced the serious (due to hospitalization) unexpected, according, events of Clostridium difficile infection and enteritis and the serious (due to important medical condition) unexpected, according, event of Prostate cancer. The event Prostate cancer occurred approximately 5 months after the second dose of mRNA-1273 vaccine, exact date of vaccination and event is not provided. The events of Clostridium difficile infection and enteritis occurred on an unknown date after the second dose of mRNA-1273 vaccine. The rechallenge was not applicable due to the nature of the event Prostate cancer and for the events Clostridium difficile infection and enteritis the rechallenge was not applicable since the events outcome was unknown. The events of Clostridium difficile infection and enteritis were considered unrelated to the vaccine per the reporter's assessment. The patient was hospitalized for a month, the outcome of the events and treatments received were not provided. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.