Neurological disease; She did not know if she was losing immunity to the vaccine; This is a spontaneous report from a contactable nurse. This 78-year-old female nurse (patient) reported for herself that:  A female patient of an unspecified age received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot Number: EL9267), via an unspecified route of administration on 17Feb2021 as DOSE 1, SINGLE, received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot Number: EN6199), via an unspecified route of administration on 10Mar2021 as DOSE 2, SINGLE for covid-19 immunisation. Medical history included pacemaker, chronic inflammatory demyelinating polyradiculoneuropathy She had the IVIg when she was diagnosed about 11 years ago , plasmapheresis She has been having plasmapheresis treatments for about 5 - 6 years now. Patient had no concomitant medications.  The patient previously took IVIg for chronic inflammatory demyelinating polyradiculoneuropathy and experienced pulmonary embolism, during the first 4-5 years she had IvIg but had the pulmonary embolism and so she was switched to plasmapheresis. On an unspecified date, the patient experienced neurological disease, she did not know if she was losing immunity to the vaccine.  She got plasmapheresis every 2 weeks for a neurological disease, she asks does the plasmapheresis pull out the antibodies that are developed from the vaccine. When she gets the treatment they pull out the plasma with the antibodies and give her human albumin, she do not know if she was losing immunity to the vaccine in this process. She was having trouble finding out. Caller confirms she called about the Pfizer Covid Vaccine, she is actually one of those people that qualifies for a booster and is eligible. She asked the pharmacist but he do not know anything. Her last plasmapheresis was about 2 weeks ago, and she was due tomorrow for her next one. Caller confirmed she got plasmapheresis every 2 weeks on a Tuesday. She just had regular lab work. It was a long time ago when diagnosing when she had unusual lab work results, but everything came negative. It was a hard time, she had a Nerve biopsy for chronic inflammatory demyelinated polyneuropathy and it showed destruction of the myelin Sheath and the axon. She got plasmapheresis every 2 weeks for a neurological disease, she asked does the plasmapheresis pull out the antibodies that are developed from the vaccine. When she got the treatment they pull out the plasma with the antibodies and give her human albumin, she didn't know if she was losing immunity to the vaccine in this process. She is having trouble finding out. Caller confirmed she called about the Pfizer Covid Vaccine. The patient underwent lab tests and procedures which included nerve biopsy: destruction of the myelin sheath and the axon on unspecified date, lab work: unusual on unspecified date, It was a long time ago when diagnosing when she had unusual lab work results, laboratory test: negative on 16Aug2021 everything came negative. The clinical outcome of events were unknown.   Follow-Up (27Aug2021): Follow-up attempts are completed. No further information is expected.