she got Plaque Psoriasis, after getting the booster, she got that Plaque Psoriasis and it came very heavily. She have it all on her body and now on her head; after she received the booster, she have an over accelerated immune system; This is a spontaneous report received from a contactable reporter(s) (Nurse), The reporter is the patient.  A 56-year-old female patient received BNT162b2 (BNT162B2), as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "COPD" (unspecified if ongoing), notes: COPD. Concomitant medication(s) included: STIOLTO RESPIMAT taken for chronic obstructive pulmonary disease; FLU VACCINE VII; PNEUMOCOCCAL VACCINE. Vaccination history included: Bnt162b2 (Dose 1, Single), for Covid-19 immunization; Bnt162b2 (Dose 2, Single), for Covid-19 immunization, reaction(s): "she had a little spot on her leg and she said it was dry and flaky and its like itchy"; Bnt162b2, for Covid-19 immunization, reaction(s): "she had a little spot on her leg and she said it was dry and flaky and its like itchy", "after I took the second dose, the starter doses, I got one of those psoriasis spot on my leg". The following information was reported: PSORIASIS (non-serious), outcome "unknown", described as "she got Plaque Psoriasis, after getting the booster, she got that Plaque Psoriasis and it came very heavily. She have it all on her body and now on her head"; IMMUNE SYSTEM DISORDER (non-serious), outcome "unknown", described as "after she received the booster, she have an over accelerated immune system". Therapeutic measures were taken as a result of psoriasis, immune system disorder.  Additional Information: Submitted by Call Centre 1 Ref: W2022418413. Agreed that report is related to a study or programme. Confirmed that the patient was also the reporter. Specified Other Health Professional as licensed practical nurse. Reason for no lot number of COVID-19 Vaccine: Reporter stated that, She was not having it in front of her. She was handicapped and cannot look for it. She did not thought about having it in front of her, said sorry. Transferring agent stated, that was there a caller to transfer. She was a patient. She was calling about the Pfizer Covid-19 vaccine. She mentioned that she already talked to several different doctors and nurses and also nurses about her condition. She said that she had always been a healthy person and all of her life, she hardly ever had a cold or flu and she was 56-years-old and she was very active, very athletic through all her life. She also said that she had come down with COPD and she took general inhalers she didn't pay any attention. Also she mentioned that she had good immune system before receiving the vaccine. She just wanted to know had that ever happened or already had that kind of situation with her. Call was transferred. said that she did the booster, it really broke out and nobody in her family had psoriasis in the past. There was no reporting of it. It was really weird all of a sudden she got it and like I said, I know the vaccines are to help boost the immune system, so wondered if her immune system got overactive because of that and if so, she want to let everyone know that, she meant talking to doctors, she was also a nurse and have already discussed it with other nurses, all LPNs, RNs and head of nursing COs at hospitals and everything was possible but it was not guaranteed that what was going on but known it was just too coincidental. she just want to kind of let all know that this was one of the symptoms that she was currently going through because of it and was due for booster but afraid to get it because if her immune system was already overactive the way it was then and the severity of the Plaque Psoriasis had taken off since the last booster and everything, it could be going to create more. She don't know, like she said I do not know if anyone else there had called and let know but she thought she would and that was the reason She called that day. Reporter was informed about the role of Pfizer Drug Safety and also informed that Pfizer Medical Information was the right department to answer the question. Reporter was provided with the number of Pfizer Medical Information # and was requested to select option 3, timings as 8 AM to 9 PM Monday to Friday as per EST. Reporter stated, Okay great, She appreciated that and like said she was not looking to yell at anybody, was just trying to let people know what she was going through so they can either research it or to see if anybody, she was trying to give a heads up maybe its something that they know particular to the drug, this was the cause and effect of these type of drug, questioned that if understanding the request. Confirmed if she was a nurse: Reporter agreed that she was an LPN. Date of vaccine administration, Reporter stated, The last one, she was going to say it was probably, she think it was Mar (Mar2022) and she know she was due for the next one. she have been due for a month or two. she think she was supposed to have the next one in July or August, something like that. (further not clarified). Any prior vaccinations (within 4 weeks): Reporter stated, No, the others she had a few months prior to that. she had a flu shot and pneumonia shot prior to that. She was on oxygen. Lab tests: Reporter stated, In the last two weeks, denied that and said she had one around a month and a half ago. Treatment in response to adverse event: Reporter stated that the doctor gave her a topical ointment to try and rub on him to stop the itching. It was the Hydrocortisone cream but that was probably about it. She was taking vitamins, folic acid things like that and B12. LOT# (Hydrocortisone): 2DT0439 and Expiration date (Hydrocortisone): Mar2024. Causality: Reporter stated,that psoriasis, she do think so just because the way it came on and she never had issues before and didn't get it until she started getting the Covid shots. So it been almost, it is 22 then, so it had been well over a year and every time she get a booster or shot, she get it more and more quickly. It kind of heat it up and think makes her immune system get active. Reporter thanked for the help. she meant like she said, was just trying to let all know about the problem about her. she hope not,hope it is just her, the stuff she was going through but just wanted to make sure if not, the people, know what she meant, she was trying to help other people more or less. Reassurance: Reporter stated,No ma'am, thanked for listening and helping her out and appreciated.  The information on the batch/lot number for [BNT162B2] has been requested and will be submitted if and when received.