Worsening of eyelids and around the eye areas are very swollen and have a rash around them/ flare up of my dermatitis; flare up of my dermatitis; eyelids and around the eye areas are very swollen and have a rash around them; eyelids and around the eye areas are very swollen and have a rash around them; This is a spontaneous report from a contactable consumer (patient) via CEP 159558. A 31-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Batch/Lot number: EL9269, Expiration date: unknown), via an unspecified route of administration in arm left (left shoulder) on 11Mar2021 at 12:20 (at the age of 31-year-old) as a dose 1, single for COVID-19 immunization. The family medical history relevant to ae(s) were reported as none. The patient's medical history included ongoing contact dermatitis and skin allergies. The patient's concomitant medications were not reported. The history of all previous immunization with the Pfizer vaccine considered as suspect was reported as none. Additional vaccines administered on same date of the Pfizer suspect was reported as none. Prior vaccinations (within 4 weeks) were reported as none. The AE(s) following prior vaccinations was reported as none. Enquired, any interaction between oral steroids like prednisone and Pfizer-BioNTech COVID-19 Vaccine.  Stated that, should the patient not take a steroid at this time. It was reported that, the patient had received the first dose of the Pfizer-BioNTech COVID-19 Vaccine on 11Mar2021, last Thursday at 12:20 in the afternoon, second dose was scheduled for 12Apr2021. Stated that, the patient had a history of contact dermatitis and skin allergies. The caller stated that, she has unrelated skin issues, contact dermatitis and has had it her entire life and was currently having a big flare up right now. Stated that, she don't believe it was related to the vaccine. Stated that, she had a flare up of her dermatitis right now, that started about 3 days ago (morning on 15Mar2021). Stated that, the caller asked whether there was an interaction with prednisone or steroids. Stated that, generally in the past, the patient had taken a prednisone or some sort of steroid for these flare ups. Stated that, it started after her first dose but she had signs of it before. Stated that, she planned to discuss this further with her physician. Stated that, eyelids and around the eye areas are very swollen and have a rash around them on 15Mar2021. Stated that, treatment included was, she used an ointment that she typically uses for her hands. The reporter clarified that, her eyelids and around the eye areas are very swollen and had a rash around them was reported as worsened and her dermatitis was flared up on an unspecified date. Stated that, the patient had skin issues unrelated to the vaccine and may need to take prednisone and would like to know whether prednisone will effect the vaccine. Any unaddressed medical questions referred or forwarded to Medical Information was reported as no. The reporter seriousness for the events eyelids and around the eye areas are very swollen and have a rash around them was reported as unspecified. The AE(s) require a visit to the emergency room and physician office was reported as no, but she did contact her Dermatologist. The investigation assessment was reported as no. The outcome of the events for eyelids and around the eye areas are very swollen and have a rash around them was reported as not recovered while for the other events was unknown.  No follow-up attempts are possible. No further information is expected.