lethargic; vomiting; diarrhea; chills with no fever; digestion issues; hands and feet were bitter cold and would not warm up; abdominal swelling and pain; abdominal swelling and pain; muscle pain; joint pain; the muscles on the side of her throat and tongue were starting to swell; had a rash on her elbow joints, thighs, buttocks, neck, lower back, and backside of thighs; itching; The muscle and joint pain started when tongue and neck were swelling; The muscle and joint pain started when tongue and neck were swelling; feeling unwell; Her left arm started swelling and was extremely sore; Her left arm started swelling and was extremely sore; injection site was really sore and really really tender/left arm started swelling; injection site was really sore and really really tender.; This is a spontaneous report from a contactable female consumer (patient). A 52-year-old female consumer received first dose of bnt162b2 (Pfizer-BioNTech COVID-19 Vaccine, solution for injection, Batch/lot number ER8730, Expiry date: unknown), via an intramuscular route in the left arm on 29Mar2021 around 09:10 to 09:15 (age at vaccination: 52-year-old), as a single dose for covid-19 immunization. Medical history included respiratory illness, in 2014 genetic / chromosomal abnormalities, endocrine abnormalities (including diabetes) and obesity, Diverticulosis diagnosed in 2014 and acid reflux or GERD Patient. Family medical history included diagnosed allergies and compromised immune status. Parents both had sore arm after receiving the COVID vaccine. Her mom received the Pfizer COVID vaccine, and her dad received the Moderna COVID vaccine. Separate report completed for them. Concomitant medication included Omeprazole 20mg once in the morning and once in the evening since 2014 for acid reflux or GERD Patient. Prior to vaccination, patient was not diagnosed with COVID-19. After first dose of vaccine, patient was really fine afterwards. On 29Mar2021 at 18:00, her injection site was really sore and really really tender, left arm started swelling and was extremely sore. Her muscles on side of throat and tongue started to swell at 18:30 and had a rash on her elbow joints, thighs, buttocks, neck, lower back, and backside of thighs, itching and was feeling unwell at 18:30 which got worsened. Rash was on both sides and also on her neck and collar area. She took a shower and hoped it helped, but it did not at the time, but now it is improved. She had pretty much all except headache and fever. She also had muscle and joint pain at 20:00. The muscle and joint pain started when tongue and neck were swelling at 18:30. On 30Mar2021, in the middle of the night, she had digestion issues at 03:30 like vomiting and diarrhea at 15:30 was an hour to hour and abdominal swelling and pain woke her out of sleep at 02:00. She has not vomited since 08:00. The diarrhea has turned into loose stools now. Her hands and feet were bitter cold and would not warm up since 02: 00, all over body chill/ chills with no fever at 14:00 and was really lethargic at 18:00. The constant coldness was making her crazy. No Emergency Room or physician's office visit required. She is asking if she would be experiencing these by her 2nd dose so that she can inform her employer. She is working and out in the public so she thought she should get it. She takes daily vitamins. She would like to know if she should expect same reaction after second dose. She is hoping that her antibodies will be built up by then and she won't have that kind of reaction. The clinical outcome of injection site was really sore and really really tender/ left arm started swelling, muscle pain, joint pain, digestion issues, lethargic was unknown; muscles of throat and tongue started to swell, her hands and feet were bitter cold and would not warm up, left arm started swelling and was extremely sore, tongue and neck were swelling, feeling unwell was not recovered and rash, itching, abdominal swelling and pain, vomiting, diarrhea was recovering/resolving.  No follow-up attempts are possible. No further information is expected.