booster; decreased appetite; nausea; tiredness; joints ache; don't feel well; fever of 100.7; vomiting; diarrhea; This is a spontaneous report from a contactable consumer. This 73-year-old female consumer (patient) reported. A 73-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, formulation: Solution for injection, Batch/Lot Number: 330268D), dose 3 via an unspecified route of administration, administered in Arm Right on 05Nov2021 (age at the time of vaccination was 73-year-old) as dose 3 (booster), single for COVID-19 immunization. Medical history included sjogren's syndrome from an unknown date and unknown if ongoing, pulmonary mass from an unknown date and unknown if ongoing (She explains she has had these nodules for about 3 years and they haven't grown any), blood cholesterol increased from an unknown date and unknown if ongoing, immunodeficiency from an unknown date and unknown if ongoing (She clarified she does have a compromised immune system). Family medical history relevant to adverse events was not provided. Concomitant medication(s) included evolocumab (REPATHA) taken at 140 mg [every 2 weeks] for blood cholesterol increased from 03Oct2021 and ongoing (The caller explained she started Repatha on 03Oct2021, her last injection she had was Sunday, 31Oct2021). Historical vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, formulation: Solution for injection, Lot number was not reported), dose 1 via an unspecified route of administration on 12Jan2021 as dose 1, single for COVID-19 immunization and experienced her arm was sore for a couple of days and she had a slight fever and that was it. Historical vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, formulation: Solution for injection, Lot number was not reported), dose 2 via an unspecified route of administration on 31May2021 as dose 2, single for COVID-19 immunization and experienced she was tired and sleepy for a couple of days and had soreness in her inner arm. The patient also administered pneumonia vaccine on an unspecified date in Mar2021 she confirmed she had no NDC, Lot or expiry date. That was all the information she could remember right then, but she had the paperwork for it somewhere.The patient did not receive any other vaccine prior to COVID-19 Vaccine prior to the first administration date of the suspect vaccine. The caller stated she was calling in regarded to the booster that she had on Friday. She clarified it was Pfizers, the one they asked her to take, and she had the two vaccines before. She clarified she was referring to the COVID-19 vaccine. The caller had booster shot on Friday, 05Nov2021. She explained she had side effects from all three vaccines, but usually the side effects were gone in three days. However, she still had tiredness, she does not feel well, she still had nausea and a decrease in appetite on 06Nov2021. She woke up Saturday morning, clarified as 06Nov2021, of a fever of 100.7, vomiting, and diarrhea, which that all went away. However, she still had the nausea and decrease in appetite.With the third dose (booster), she experienced fever, vomiting, diarrhea, had the tiredness feeling, and her joints ache. She confirmed she was still experiencing the tiredness, nausea, and decrease in appetite. She mentioned she has a lot going on, but at one time she was having problems with nausea, she does not remember what she had going on, but her gastroenterologist gave her some medication that she took off and on as needed. She had not had to take any in about 6 months when she just had a little nausea before. The caller stated the main reason she called was because she was just wondering if this was normal for the symptoms to last this long. The event did not result in doctor or other healthcare professional office/clinic visit. The patient underwent lab tests and procedures which included body temperature: 100.7 on 06Nov2021. Outcome of the events decreased appetite, nausea, tiredness, do not feel well was reported as not recovered and outcome of the events fever of 100.7, vomiting, diarrhea and joints ache was reported as Unknown at this time of the report.   Follow-up attempts are completed. No further information is expected.