This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 71-year-old female patient who received SHINGRIX for prophylaxis.  Concomitant products included hydrochlorothiazide. On 22nd May 2018, the patient received the 1st dose of SHINGRIX (intramuscular). On 22nd May 2018, less than a day after receiving SHINGRIX, the patient experienced injection site pain, injection site erythema and injection site warmth. On 30th May 2018, the patient experienced pain in joint involving hand and arthritis. The patient was treated with ibuprofen and camphor + levomenthol + melaleuca (nos) + methyl salicylate (Pain-A-Trate). On an unknown date, the outcome of the injection site pain, injection site erythema and injection site warmth were recovered/resolved and the outcome of the pain in joint involving hand was unchanged and the outcome of the arthritis was unknown. The reporter considered the injection site pain, injection site erythema, pain in joint involving hand, injection site warmth and arthritis to be related to SHINGRIX. Additional details were provided as follows: The reporter was reporting this case for herself. The vaccine was administered into her left upper arm. The patient did not know exact dosing details of this first dose in the series. In the evening of the day of vaccination, the patient experienced injection site pain, injection site erythema and injection site warmth. The pain at the injection site had been tender but not unbearable. The patient had noticed the pain at the injection site only if she rolled onto her arm at night. Then, sometime last week on Wednesday, 30th May 2018, (or possibly before Wednesday) 8 days after vaccination, the patient noticed both of her thumbs hurting. She was alarmed by this symptom which was unchanged till the time of reporting. She described the thumb pain as being thumb joint pain as though it might be arthritis though she has never had arthritis (further details were not specified). On Thursday, 31st May 2018, she became concerned when lifting a pot because of her thumbs hurting so much. She was concerned about her hands becoming weak while lifting because of her thumbs hurting so much, stating her hands were not actually weak but that lifting the pot felt unusual in that she had been holding the pot in a way trying not to make her thumbs hurt and so had been favoring her hands while lifting the pot. She had been having more thumb joint pain in the left thumb than the right. She took an over the coun ter (OTC) Ibuprofen at the night before reporting for the pain. A day before the date of reporting in the afternoon, she rubbed a product called Pain-A-Trate into her hurting thumb joint area. The patient had denied permission to contact their physician. She knew the street where the doctor's office was located but not further specified. She could only provide the name of one of her routine medicines during the call, as she did not have her list of medications handy during the call. The reporter would be contacted for further related questions. The reporter did not know, except it was not the doctor who administered the vaccine but another office staff member whose name or title she did not know. This case has been linked with US2018GSK101153 and US2018GSK101152 by the same reporter.