Broke out in hives; She felt itchy; Feel sick; Really, really bad headache; This is a spontaneous report from a contactable consumer or other non hcp (patient). A 32-years-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; formulation: Solution for injection, Batch/Lot Number: EW0179), via an unspecified route of administration, administered in Arm Left on 13May2021 (at the age of: 32-years-old) as dose 2, single for COVID-19 immunization. The patient medical history included fibromyalgia from 2019 and ongoing Officially diagnoses in 2019 but it took 10 years to get the diagnosis, Interstitial cystitis from 2019 and ongoing, pelvic floor dysfunction from 2016 and ongoing, IBS (irritable bowel syndrome), Gastritis or reflux, Mental health bipolar ADHD anxiety, Familial Chromosomal Duplication, Fibro and for night restless leg and twitching and stuff, Mood stabilizer and insomnia medication, Muscle relaxer and Gastritis. The patient concomitant medications included bupropion hydrochloride (WELLBUTRIN), as 150, Caller does not specify units, is a combo med for her nervous system, depression, anxiety, and aggression and irritation. She has been on for a couple of months. She develops weird side effects to medications, so ones that work they try to keep her on, pregabalin (LYRICA) taken for restless legs syndrome (Fibro and for night restless leg and twitching and stuff), as 50 mg, 1x/day (1 at night) she could not tolerate it during the day so she takes it at night; quetiapine fumarate (SEROQUEL) taken for insomnia (Mood stabilizer and insomnia medication) as 50-75 mg; chlorzoxazone (CHLORZOXAZONE) taken for muscle relaxant therapy, as 500, caller does not specify units; omeprazole (PRILOSEC) taken for gastritis, as 40, caller does not specify units She had surgery and it flared the gastritis and her surgery was prior to the vaccines; paracetamol (TYLENOL) states she does not take for her fibro, she takes for headaches and stuff like sinus pain or something, every once in a while as Extended release arthritis 625; xylometazoline hydrochloride (SUDAFED) she takes once in a while she will take Sudafed if she cannot breathe at night. She was bad with her CPAP, and she cannot stand the way it feels. The patient previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; formulation: Solution for injection, Batch/Lot Number: EW0162), via an unspecified route of administration on 20Apr2021 as dose 1, single for covid-19 immunization. Patient was not sure that this is going to be considered abnormal for her and that's why she asked her doctor if she had to report it. She broke out. She got the vaccine last Thursday and was very busy and distracted. On 14May2021, the patient experienced Broke out in hives, she felt itchy, Feel sick, and Really, really bad headache. Caller stated, she felt itchy but did not notice until Friday morning when she went into the shower that she was in hive. she had tons of diagnoses and had an immune reaction anyways. She tends to break into hives anyways when she started to get sick. she had triamcinolone cream that is why she used it, when she had contact reactions and she had not taken anything for the headache except for Tylenol on Friday. She was drinking more water. Patient stated that these are all her normal ones, and she cannot remember using anything else. The only other prescription stuff she had was triamcinolone and a face and scalp cream from the dermatologist. she had fibro and so the way the doctor said it was her nervous system was so wacky because of the fibro and the other systems her body was a warning system of immune reaction when she starts to get sick. she had a diagnosis from head to toe, they are all linked to fibro. It effects muscles and plantar fasciitis and nerve problems with her feet. If she starts to feel sick, but she was unsure, she was generally sick if she starts to break into hives. She eventually got triamcinolone cream continuously prescribed for these instances. she was confused because this only happened after the second vaccine. patient states that she only had a really, really bad headache and hives. The headache is starting to go away. The headache started as soon as she woke up on Friday morning. Her youngest son had a doctor's appointment and his GI doctor told her the headache was common and would go away and she had a bad headache. That was just her sons GI doctor that told her the headache was fine. The patient received treatment for all the events. The outcome of the events broke out in hives, She felt itchy was recovering; and events feel sick, headache was unknown.  No follow-up attempts completed. No further information expected.