Swelling in wrist; little bump that was itchy; small bumps. About 4-5 hours later it worsened; Pain in her arm; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP), Program ID. The reporter is the patient.  A 69-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 24Oct2022 as dose 4 (booster), single (Lot number: GH9693) at the age of 69 years, in right arm for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: BNT162b2 (Dose: 01, Lot: 30135BA), administration date: 13Oct2021, when the patient was 68-year-old, for COVID-19 immunization, reaction(s): "Pain in her arm"; BNT162b2 (Dose: 02, Lot: FH8020), administration date: 03Nov2021, when the patient was 68-year-old, for COVID-19 immunization, reaction(s): "Pain in her arm"; BNT162b2 (Dose: 03, 1st booster, Lot: FU9899), administration date: 22Apr2022, when the patient was 69-year-old, for COVID-19 immunization, reaction(s): "Pain in her arm", "Swelling in wrist", "It got worse and itchy", "It swelled up like a blister almost . She bumped it and the blister broke so since it was exposed she kept a bandaid on it", "She still has a scar on her right wrist from last time". The following information was reported: PAIN IN EXTREMITY (non-serious) with onset Oct2022, outcome "unknown", described as "Pain in her arm"; JOINT SWELLING (non-serious) with onset 26Oct2022, outcome "not recovered", described as "Swelling in wrist"; RASH PRURITIC (non-serious) with onset 26Oct2022, outcome "unknown", described as "little bump that was itchy"; CONDITION AGGRAVATED (non-serious) with onset 26Oct2022, outcome "unknown", described as "small bumps. About 4-5 hours later it worsened". Therapeutic measures were not taken as a result of joint swelling, rash pruritic, condition aggravated, pain in extremity.  Additional information: It was reported that patient had swelling in wrist was reported as worsened started as a little bump that was itchy. It got worse and swells up again. It gets itchy and it gets worse and swells up again then, it weeps a liquid. patient stated that when this was occurred in Apr2022, she did not think it was related to the COVID vaccine because it happened 1.5 days later. She thought it was like a spider bite. It got worse and itchy. It lasted about 2 weeks that time. It was her right wrist last time, and she thinks she got the COVID vaccine in her left arm. It swelled up like a blister almost. She bumped it and the blister broke so since it was exposed, she kept a band aid on it. Since, it happened again this time she thought wait a minute this happened last time. It has happened in the opposite arm she received the vaccine in both times. She got her original vaccines back in 2021, and this didn't happen. It only happened with the boosters. She alternated arms for the boosters. She had pain in her arm after the boosters. She still has pain in her arm from this booster. Even with the original series, she had pain in her arm. Her wrist is in the weeping stage now. It was worsening. It started yesterday 26Oct2022 with small bumps. About 4-5 hours later it worsened. Her shot was in her right arm on Monday. The swelling is in her left wrist. She still has a scar on her right wrist from last time. There was no treatment given for this time, but last time bandaged and over the counter antibiotic creams was given.