When it happens, I feel heaviness behind my eyes; I get sweaty palms, here & there; When the intensity is worst, I get a spasm & erratic movement in my arms, feet, & hands.; erratic movement; I started yawning a lot, many times; I feel a loss of sensation in my lower bicep,when I'm using my arms is when I feel the sensation of warmness & loss of sensation; It felt like a panic attack; It triggers this fear that something bad is going to happen to me; He feels like he's withering away; My arm felt really warm; there was numbness in left arm; tingling in his arms - it starts in his left arm, tingling in his legs.; He started feeling extreme exhaustion/extreme tiredness; He felt a burning sensation in the left arm, it travels around my body, even to my legs,It then spreads to other body parts; the lymph nodes under his arm were in pain; chills; arm pain; He had a strong headache/Minor headache; This spontaneous case was reported by an other health care professional and describes the occurrence of FEELING ABNORMAL (He feels like he's withering away), PARAESTHESIA (tingling in his arms - it starts in his left arm, tingling in his legs.), SKIN WARM (My arm felt really warm), HYPOAESTHESIA (there was numbness in left arm), FEAR (It triggers this fear that something bad is going to happen to me), FATIGUE (He started feeling extreme exhaustion/extreme tiredness) and HEADACHE (He had a strong headache/Minor headache) in a 31-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014F21A, 001A21A and 028L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 25-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 22-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Nov-2021, the patient experienced HEADACHE (He had a strong headache/Minor headache) (seriousness criterion medically significant), PAIN IN EXTREMITY (arm pain), LYMPH NODE PAIN (the lymph nodes under his arm were in pain) and CHILLS (chills). On 09-Nov-2021, the patient experienced PARAESTHESIA (tingling in his arms - it starts in his left arm, tingling in his legs.) (seriousness criterion medically significant), FATIGUE (He started feeling extreme exhaustion/extreme tiredness) (seriousness criterion medically significant) and BURNING SENSATION (He felt a burning sensation in the left arm, it travels around my body, even to my legs,It then spreads to other body parts). On 14-Nov-2021, the patient experienced SKIN WARM (My arm felt really warm) (seriousness criterion medically significant) and HYPOAESTHESIA (there was numbness in left arm) (seriousness criterion medically significant). On 16-Nov-2021, the patient experienced FEELING ABNORMAL (He feels like he's withering away) (seriousness criterion medically significant) and FEAR (It triggers this fear that something bad is going to happen to me) (seriousness criterion medically significant). On 25-Nov-2021, the patient experienced PANIC ATTACK (It felt like a panic attack). On 29-Nov-2021, the patient experienced SENSORY LOSS (I feel a loss of sensation in my lower bicep,when I'm using my arms is when I feel the sensation of warmness & loss of sensation) and YAWNING (I started yawning a lot, many times). On 30-Nov-2021, the patient experienced MUSCLE SPASMS (When the intensity is worst, I get a spasm & erratic movement in my arms, feet, & hands.) and DYSKINESIA (erratic movement). On an unknown date, the patient experienced OCULAR DISCOMFORT (When it happens, I feel heaviness behind my eyes) and HYPERHIDROSIS (I get sweaty palms, here & there). The patient was treated with CANNABIS from 25-Nov-2021 to 30-Nov-2021 at an unspecified dose and frequency. At the time of the report, FEELING ABNORMAL (He feels like he's withering away), FEAR (It triggers this fear that something bad is going to happen to me), YAWNING (I started yawning a lot, many times) and PANIC ATTACK (It felt like a panic attack) outcome was unknown, PARAESTHESIA (tingling in his arms - it starts in his left arm, tingling in his legs.), SKIN WARM (My arm felt really warm), HYPOAESTHESIA (there was numbness in left arm), PAIN IN EXTREMITY (arm pain), BURNING SENSATION (He felt a burning sensation in the left arm, it travels around my body, even to my legs,It then spreads to other body parts), LYMPH NODE PAIN (the lymph nodes under his arm were in pain) and CHILLS (chills) was resolving and FATIGUE (He started feeling extreme exhaustion/extreme tiredness), HEADACHE (He had a strong headache/Minor headache), SENSORY LOSS (I feel a loss of sensation in my lower bicep,when I'm using my arms is when I feel the sensation of warmness & loss of sensation), MUSCLE SPASMS (When the intensity is worst, I get a spasm & erratic movement in my arms, feet, & hands.), DYSKINESIA (erratic movement), OCULAR DISCOMFORT (When it happens, I feel heaviness behind my eyes) and HYPERHIDROSIS (I get sweaty palms, here & there) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 14-Nov-2021, Blood pressure measurement: results not reported (Inconclusive) results not reported. On 14-Nov-2021, Heart rate: 125 beats/min (High) 125 beats/min. On 29-Nov-2021, Neurological examination: results not reported (Inconclusive) results not reported. On 29-Nov-2021, SARS-CoV-2 test: results not reported (Inconclusive) results not reported. On an unknown date, Blood test: results not reported (Inconclusive) results not reported. On an unknown date, Electrocardiogram: results not reported (Inconclusive) results not reported. On an unknown date, Heart rate: 50 (normal) normal heart rate is around 50.. On an unknown date, Neurological examination: results not reported (Inconclusive) results not reported.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medications were not provided by the reporter. Patient runs 2 miles/day. He's in good shape. Patient called 911 on 14 NOV 2021, took heart rate and BP, patient decided to stay home rather than going to the hospital. On 16Nov2021 Patient went to the emergency room due to extreme tiredness. On 29 Nov 2021, patient went to urgent care to get another opinion, They checked the tests results from the ER visit on 16 Nov 2021. The Urgent Care said that patient will  be receiving a call for an appointment with neurology. The Dr there feels it might have something to do with the booster shot.   Company comment: This is a spontaneous case concerning a 31-year-old male  patient with no medical history reported, who experienced serious events of feeling abnormal, paraesthesia, skin warm, Hypoasthesia, fear, fatigue and headache. The event headache occurred approximately 1 day after the third dose of mRNA-1273 vaccine. Events fatigue and paraesthesia occurred approximately 7 days after the third dose. Events skin warm and Hypoasthesia occurred approximately 12 days after the third dose. Events fear and feeling abnormal occurred approximately 14 days after the third dose. Patient went to the emergency room due to extreme tiredness and he stated that the Dr. there feels it might have something to do with the booster shot. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2021-403262, MOD-2021-403254 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 30-Nov-2021: Significant follow up received, case upgraded to serious, events, lab data, treatment medication and reporter and patient information updated.; Sender's Comments: This is a spontaneous case concerning a 31-year-old male  patient with no medical history reported, who experienced serious events of feeling abnormal, paraesthesia, skin warm, Hypoasthesia, fear, fatigue and headache. The event headache occurred approximately 1 day after the third dose of mRNA-1273 vaccine. Events fatigue and paraesthesia occurred approximately 7 days after the third dose. Events skin warm and Hypoasthesia occurred approximately 12 days after the third dose. Events fear and feeling abnormal occurred approximately 14 days after the third dose. Patient went to the emergency room due to extreme tiredness and he stated that the Dr. there feels it might have something to do with the booster shot. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.