anaphylactic reaction; both of the palms were crazy itchy and red/ face was red; both of the palms were crazy itchy and red; throat got kind of constricted; Sore throat; Fever; uvula was larger and red; uvula was larger and red; really tired; This is a spontaneous report from a contactable Other health care professional. A 75-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Lot number: EL9265, Expiration date: 31May2021, NDC number: Unknown), intramuscularly in left upper arm on 29Jan2021 09:20 AM at single dose for preventative/ COVID-19 immunisation in hospital. The patient's medical history included thyroid from an unspecified date in Aug2020 and ongoing, ongoing high blood pressure (diagnosed about a year to a year and a half ago), ongoing osteoporosis (diagnosed over 10 years ago). Patient had history of allergies to Codeine and non steroidal anti inflammatory (NSAIDS). The patient was not taking any medication prior to the event being reported. Patient did not receive any recent vaccines for any other conditions prior to the event being reported. Patient did not receive any recent vaccines for SARS-CoV2 other than Pfizer-BioNTech COVID-19 Vaccine prior to the event . Patient did not received any other vaccines around the time of Pfizer-BioNTech COVID-19 Vaccine. There was no multiorgan involvement. Concomitant medications included ongoing amlodipine besylate (Formulation: Tablet, Strength: 2.5 mg) at 2.5 mg, once a day for blood pressure, ongoing levothyroxine sodium (Formulation: Tablet, Strength: 50 ug), orally at 50 ug, once a day (50mcg tablet once a day at night) for thyroid, ongoing calcitonin/ salmon via nasal at once a day (one squirt in each nostril once a day, alternating nostrils) (states it was a spray and she reads 200 unit/act sprAPOT) for osteoporosis. She would be checked on 18Feb2020 to see if her medication needs to be changed. Prior vaccinations (within 4 weeks) was none. Adverse events following prior vaccinations was none. Additional vaccines administered on same date of the Pfizer suspect was none. She got the first dose of the Pfizer vaccine last Friday. She got a whole bunch of paperwork and it said if there was a possible side effect to report it. Reports something really weird happened on Tuesday. At first it seemed like it had to be a side effect because she didn't do anything abnormal or out of her routine. She was eating breakfast and both palms of her hands started itching like crazy, it was a crazy itch on 02Feb2021. Her palms were all red which may have been from her rubbing them to try and get rid of the itch on 02Feb2021, this went away the same day. Her throat got kind of constricted on 02Feb2021 and by the next morning it was better. She could breath and swallow, but it felt really thick. She looked in the mirror, and the thing that hangs down, she clarifies her uvula was larger and very red on 02Feb2021. Her face was also red. She sat it out and took her vitals. She was tired but it did not stop her, she still did a two-mile walk. States she was fine enough to do that. Her throat was sore on 02Feb2021 all day and into the night, her sore throat on 02Feb2021 was the longest lasting side effect, it recovered the next day. Her fever was 99.5 on 02Feb2021 and states her temperature was usually 97 or 96. Her pulse ox was 96. Her pulse was 70. Her blood pressure was 138/76, which was not abnormal for her first thing in the morning. She felt abnormally really tired on an unspecified date in Feb2021. She took Tylenol. She was fine with everything by Wednesday. The following day it was all done and over with. Patient experienced itchy,Red palms,sore throat,swollen uvula,too urinating,welling instill less than 24 hours.4 days later the patient had anaphylactic reaction. Patient did not required medical intervention. Patient was not seen in emergency department. She was not hospitalized. She was not admitted to an intensive care unit. Patient was given Benadryl. Her and her husband went to get the vaccine together. He did not have anything like this. She was thankful to Pfizer for making the vaccine. She just experienced a little blip in her day, she was not complaining. Weight: 128-130 pounds. The adverse events did not require a visit to emergency room and physician office. Relevant tests was none. Investigation assessment was none. The outcome of the event really tired was unknown, recovered on an unspecified date in Feb2021 for the events uvula was larger and red, fever, recovered on 03Feb2021 for the events sore throat, throat got kind of constricted and recovered on 02Feb2021 for the other events. The patient was recovered from anaplylactic reactions. The Pfizer product had a causal effect to the adverse event  Follow-up 02Mar2021: Significant information received and updated. This is a follow-up spontaneous report from a contactable Other HCP. This Other HCP reported in response to HCP letter sent. Updated reporter in case and in narrative. Upgraded case to serious by adding anaphylactic reaction as an event. Added patient medical history. Added outcome and updated narrative.