VERY SEVERE UTI; FEELING OF JUST BEING FULL WHEN JUST  EATING LITTLE BIT( CAN'T EAT A FULL MEAL); ENLARGED SPLEEN; COULDN'T STAY AWAKE FOR MORE THAN 2  HOURS; VIRAL INFECTION; FEELING EXHAUSTED; HEART ATTACK; This spontaneous report received from a patient concerned a 70 years old female. The patient's height and weight were not reported. The patient's concurrent conditions included muscle relaxants and penicillin allergy and other pre-existing medical conditions included that she had always been a healthy person. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of administration was not reported, batch number: 1805025 and expiry: unknown) dose was not reported, dose number in series was 1, 01 total administered on 11-MAR-2021 to left arm for prophylactic vaccination. No concomitant medications were reported.  On 10-APR-2021, the patient got diagnosed with a Heart attack after she had severe Jaw pain and they did EKG (Electrocardiogram) decided that she needs stents placed. On 06-SEP-2021 (labor day) she went to the emergency room (ER) because she was feeling exhausted (end up taking a nap during the day) and couldn't stay awake for more than 2 hours. They said she had a viral infection. Laboratory data included: coronavirus disease (COVID-19) virus test with result negative (tested at emergency room). On 13-SEP-2021 (Monday) she went to ER again and they said that she still had the same viral infection (she doesn't know exactly the name of the viral infection). Laboratory data included: COVID-19 (Coronavirus disease) virus test with result negative (tested at emergency room) On 16-SEP-2021, she went to see her nurse practitioner who said she had a very severe urinary tract infection (UTI) and put her on an antibiotic (does not know the name of the antibiotic) and did blood test and saw some elevations in different things (blood counts) and sent her to a hematologist. On 24-SEP-2021, Laboratory data included: Computerised tomogram (CT) scan with result spleen was enlarged. On 30-SEP-2021 she saw hematologist for the first time. On 06-OCT-2021, Laboratory data included: Bone marrow biopsy with result negative. On 27-DEC-2021, Laboratory data included: COVID-19 virus test with result negative (tested at doctor's office). On an unspecified date, the patient experienced feeling of just being full when just eating little bit (can't eat a full meal), enlarged spleen (dose number in series was 1), Laboratory data (dates unspecified) included: CT scan with result normal. She had visited the physician's office. It was reported that, on 19-JAN-2021 (Wednesday) the patient had CT (computerized tomography) scan done with contrast on spleen. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from feeling exhausted, feeling of just being full when just eating little bit( can't eat a full meal), very severe UTI, and viral infection, and the outcome of heart attack, enlarged spleen, severe jaw pain and couldn't stay awake for more than 2 hours was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: 20220126598- COVID-19 VACCINE AD26.COV2.S- Heart attack. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).