Excruciating pain in leg/slightly sore arm/miniscule sore arm; Leg inflammation; She couldn't even sleep; Swelling in the right ankle; PTSD; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team,. The reporter is the patient.  A 70-year-old female patient received BNT162b2 (BNT162B2), on 04Oct2021 as dose 3 (booster), single (Lot number: 30145817) at the age of 68 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Hip pain" (unspecified if ongoing); "Hip surgery", start date: 15Mar2021 (not ongoing), notes: she had surgery, hip surgery, 15Mar2021, she was ready for them to chop her leg off; "Hip replacement" (not ongoing); "Plastic Surgery on her body" (not ongoing); "High cholesterol" (ongoing); "Pre diabetic" (ongoing); "High blood pressure" (ongoing); "Nerve pain" (ongoing); "Spinal stenosis" (ongoing); "Sleep" (ongoing); "Arthritis" (unspecified if ongoing). Concomitant medication(s) included: ROSUVASTATIN taken for blood cholesterol increased (ongoing); METFORMIN taken for glucose tolerance impaired (ongoing); LISINOPRIL taken for hypertension (ongoing); XANAX taken for sleep disorder (ongoing); GABAPENTIN taken for neuralgia, spinal stenosis (ongoing). Vaccination history included: BNT162b2 (Dose 1, Single, Batch/Lot Number: EN6201), administration date: 08Feb2021, for COVID-19 immunisation, reaction(s): "Slightly sore arm/excruciating pain in leg", "Excruciating pain in hip", "Leg inflammation", "She couldn't even sleep"; BNT162b2 (Dose 2, Single, Batch/Lot Number: EN6198), administration date: 01Mar2021, for COVID-19 immunisation, reaction(s): "Slightly sore arm/excruciating pain in leg", "Excruciating pain in hip/Within a few days of second dose, hip pain started", "Leg inflammation", "She couldn't even sleep", "PTSD"; Tetanus vaccine (was 19 then. Normally, does not get bad reactions.), for Immunisation, reaction(s): "Couldn't move Arm for a month", "Her arm hurt". The following information was reported: PAIN IN EXTREMITY (medically significant), outcome "unknown", described as "Excruciating pain in leg/slightly sore arm/miniscule sore arm"; INFLAMMATION (non-serious), outcome "unknown", described as "Leg inflammation"; INSOMNIA (non-serious), outcome "unknown", described as "She couldn't even sleep"; JOINT SWELLING (non-serious), outcome "unknown", described as "Swelling in the right ankle"; POST-TRAUMATIC STRESS DISORDER (non-serious), outcome "unknown", described as "PTSD". The events "excruciating pain in leg/slightly sore arm/miniscule sore arm", "leg inflammation", "she couldn't even sleep", "swelling in the right ankle" and "ptsd" required physician office visit. The patient underwent the following laboratory tests and procedures: Antibody test: Gone down to 800; Antinuclear antibody: Normal; Blood test: Good/fine; Magnetic resonance imaging: Everything was fine; Red blood cell sedimentation rate: Normal; X-ray: Everything was fine. Therapeutic measures were taken as a result of pain in extremity, inflammation, insomnia, joint swelling. Clinical Course: Got booster dose Oct2021. All ready had hip issues, since she had to get hip replacement. So, she all ready had some pain in that hip. By the time she had surgery, hip surgery, 15Mar2021, she was ready for them to chop her leg off. Thinks she had PTSD from it. When she got booster dose, Oct2021, 6 months post op, the same symptoms occurred again. With the booster dose, the pain didn't start until about 4 days after she got the booster.  Had MRI Scan and X-rays done and, everything was fine. No other symptoms other than when she got the vaccines. Clarified with caller, that she was reporting issues with excruciating pain in hip and leg, every time she got doses of Pfizer BioNTech Covid-19 vaccine. Finally put together what happened. Should had realized sooner. When she got the booster, had the same reaction and the light bulb went off. All of a sudden, looked at calendar when they were scheduling surgery. Was doing pretty good and hadn't had the surgery yet. Thought she would get over it, didn't want to have stroke. 10 days later, she got the vaccine and, within a week, was back in the office. Was begging them to move up the surgery, was all of a sudden in excruciating pain. Seemed a little puzzled by the severity at the time but, nobody really put it together. Should have realized because, it happened again, with the booster. It was 6 months, post operatively. The reason she called, was to see if she could maybe get the child dose. Clarified this was addressed with , prior to transfer. They told her it was not approved her to get the child dose. Clarified that caller was having the hip pain prior to having the vaccines. Slightly sore arm: Was either the next day, after each shot or later that day. It was not severe at all, was mild. When she had the booster, 6 months post operatively, by then, the severe pain from the hip was gone. She had the surgery, and had recovered. That time, it lasted an entire week. Had the shot on a Monday night, Friday night, she was not able to sleep because of the pain. Lasted an entire week. As weird as it came, it went. This was 6 months post operatively, that she had the third Pfizer vaccine. All she had was, like a miniscule sore arm for a few days. Friday, started having severe pain, it took a while to get over to the leg. It was just the right leg. Even had swelling in the right ankle. Hip surgeon said it was not coming from her hip. Pain was in entire right leg, down to the ankle. Treatment: Had Hydrocodone left over from surgery, that she took. The first time this happened, before the surgery, they gave her Tramadol, that did absolutely nothing. Just suffered the 6 weeks until she had the surgery. The third time, when she had the booster, she had Hydrocodone left over form surgery, that she took and it did nothing. Would doze off, maybe a half hour, and wake up from pain again and doze off for maybe a half hour. It was the worst pain she ever had and, she has had plastic surgery on her body, and lots of stuff. The surgeon gave her Tramadol, which she mentioned didn't work. Was taking it at bedtime, it didn't help. Funny because, she thought it was just her hip going bad. Other than moving her surgery up, really didn't go anywhere. Thought they probably wouldn't be able to do anything. Probably should have gone to the ER (Emergency Room). They were weird in ER (Emergency Room) in (state withheld), about giving anybody controlled substances for pain. She probably would have gotten addicted because that pain was just so unbearable. She didn't go, because she thought they would just give her Hydrocodone, which she did not want, or Oxycontin. Hoped it would go way. It did with third booster. It only lasted one week. Just wants to get another booster, feels so unprotected. Asking if Pfizer would know if they think that the Mrna, the spike protein that attacks, if there is something all ready inflamed in the body. Do the spike proteins go there? Is that what happened? Knows people that have MS (Multiple Sclerosis), got flare ups from the vaccine. If there is all ready something wrong in the body, this vaccine goes haywire. Caller declined to be transferred back to  to address these questions. Does not think they had any answers about that. Is just afraid to take the Mrna. Had taken vaccines her whole life, for everything. The only bad reaction she had was to a tetanus vaccine. Her arm hurt and couldn't move it for a month. She was 19 then. Normally, does not get bad reactions. Had tetanus shots since the, had the triple one. Has had 3 of those, over the past 50 years and, was fine. Does not normally have horrible reactions. Told her doctor, she had PTSD from this. It was so awful, was at the point where she wanted them to chop the whole damn leg off. They would have thought she was nuts if she went to the ER (Emergency Room). Caller states she doesn't know if Pfizer makes a non mRNA Covid vaccine. The caller was inquiring if she could get a booster shot for the COVID-19 vaccine, as she had some pains when she took the regular dose of vaccines. She had the same pains at the hip when she took the first and second doses. She would want to get the booster, but she is asking if she can get the booster for children. Caller stated it was the "worst pain of her life" She got the vaccine "right before getting a hip replacement and already had some pain obviously." She received the first dose in Feb2021 and the second dose three weeks later on 01Mar2021. She only had a slightly sore arm at first with each dose but within a few days of each dose the hip pain and leg inflammation started. The hip/leg pain didn't completely go way after the first dose. "It was so severe she couldn't sleep even with hydrocodone. By the time she had the surgery on 15Mar she was ready for them to chop her leg off." Caller stated she had PTSD from it. The entire leg was inflamed, and She had to go to bed with three ice packs on her leg." The booster dose was given 6 months post op in Oct2021. The same symptoms occurred again with the booster dose however the pain didn't start until about 4 days post booster injection. Gabapentin: Does not know if she was taking this prior to this all occurring with hip pain, she may have been. Is still taking, now, Lisinopril: Been taking 25 years, Metformin: Been taking like 15 years Has never been full diabetic, Rosuvastatin: Clarified that she takes Rosuvastatin, which is generic for Crestor Been taking years, cant even tell.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300079702 same patient, same product, different dose/events;