progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; headache; new onset paresthesia in my legs while standing at work/paresthesia in my lower extremities from my buttocks to my feet; progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; This is a spontaneous report received from contactable reporter(s) (Nurse). The reporter is the patient.  A 67-year-old male patient received BNT162b2 (BNT162B2), on 21Nov2021 as dose 3 (booster), single (Lot number: FE3594) at the age of 65 years for covid-19 immunisation. The patient's relevant medical history included: "Hypertension" (unspecified if ongoing); "Diabetes" (unspecified if ongoing); "High Cholesterol" (unspecified if ongoing); "Gout" (unspecified if ongoing); "if covid prior vaccination: Yes" (unspecified if ongoing), notes: if covid prior vaccination: Yes. Concomitant medication(s) included: AMLODIPINE;OLMESARTAN; JANUMET; CRESTOR; PROPANOLOL [PROPRANOLOL]. Past drug history included: Aspirin, reaction(s): "known allergies: Aspirin Intolerance", notes: known allergies: Aspirin Intolerance. Vaccination history included: BNT162b2 (DOSE 1, SINGLE; Lot number: EN6207, Administrator route: Intramuscular; Location of injection: Arm Left), administration date: 06Apr2021, when the patient was 64-year-old, for COVID-19 Immunization; BNT162b2 (DOSE 2, SINGLE; Lot number: EW01050, Administrator route: Intramuscular; Location of injection: Arm Left), administration date: 27Apr2021, when the patient was 64-year-old, for COVID-19 Immunization, reaction(s): "Headache", "new onset paresthesia in my legs while standing at work", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.", "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.". The following information was reported: ASTHENIA (non-serious), FATIGUE (non-serious), MUSCLE SPASMS (non-serious), PAIN (non-serious), CONDITION AGGRAVATED (non-serious), outcome "not recovered" and all described as "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet."; HEADACHE (non-serious), outcome "not recovered"; PARAESTHESIA (non-serious), outcome "not recovered", described as "new onset paresthesia in my legs while standing at work/paresthesia in my lower extremities from my buttocks to my feet". The events "progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.", "headache" and "new onset paresthesia in my legs while standing at work/paresthesia in my lower extremities from my buttocks to my feet" required physician office visit. Therapeutic measures were not taken as a result of asthenia, fatigue, muscle spasms, pain, headache, paraesthesia, condition aggravated.  Additional information: The following day after the 2nd dose, I suddenly developed a very severe headache and new onset paresthesia in my legs while standing at work, so bad that I had to call for assistance for support back to a chair. The symptoms resolved after a few minutes but that was the beginning of progressively worsening weakness/fatigue, cramps, deep pain, and paresthesia in my lower extremities from my buttocks to my feet.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300286687 Same patient/drug/AE, different dose.;