Hemoglobin has dropped; This is a spontaneous report from a contactable consumer (patient's wife) via the Pfizer-sponsored program. An 84-years-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection), dose 2 via an unspecified route of administration, administered in arm left on 28May2021 (at the age of 84-years-old) (Batch/Lot Number: EW0172) as DOSE 2, SINGLE; and dose 1 via an unspecified route of administration, administered in arm left on 07May2021 (at the age of 84-years-old) (Batch/Lot Number: EW0172) as DOSE 1, SINGLE for COVID-19 immunisation. Medical history included cardiac congestive heart failure from Feb2020 and ongoing; quadruple bypass surgery 35 years ago, had low hemoglobin that was stabilized after receiving RETACRIT infusions, internal haemorrhage and anaemia. There were no concomitant medications. The patient previously took Retacrit Epoetin Alfa [epoetin alfa epbx] since Mar2021 for low hemoglobin, internal haemorrhage and anaemia. The patient had no prior vaccinations within 4 weeks prior covid-19 vaccine. It was reported that the vaccine doses were given on 07May2021 and 28May2021. It was mentioned that prior to vaccination the patient had low hemoglobin that had stabilized after receiving RETACRIT infusions. After vaccination, his hemoglobin has dropped and he needed RETACRIT infusions again. The reporter wanted to know if this happened to anyone else. The patient has had a problem with his hemoglobin levels ever since he got both COVID-19 Vaccine doses. The patient was getting infusions (RETACRIT) prior to the COVID-19 vaccine doses. It was mentioned that he did not have any infusions for 8 weeks prior to the COVID-19 vaccine doses. The patient's hemoglobin dropped after getting both COVID-19 vaccine doses in Jun2021. The reporter (patient's wife) asked if her husband's hemoglobin dropping was a side effect of the COVID-19 vaccine. Her husband received his first COVID-19 Vaccine dose on 07May2021 and his second COVID-19 vaccine dose on 28May2021. The reporter mentioned that she and her husband (patient) was originally not going to get the COVID-19 vaccine because they both react to so many things. Their doctor told them if they got the COVID-19 virus, they wouldn't survive, so she and her husband got the COVID-19 vaccine. It was clarified that the patient had been getting a clear liquid injected (called Retacrit Epoetin Alfa) into his arm every week since Mar2021. The patient was taking the Retacrit Epoetin Alfa for some internal bleeding, and anemia. After 8 weeks of taking the Retacrit Epoetin Alfa, her husband's hemoglobin was at a safe level. When her husband received both COVID-19 Vaccine doses, his hemoglobin dropped afterwards. Her husband had to go back to getting weekly Retacrit Epoetin Alfa shots. Therapeutic measures were taken as a result of hemoglobin has dropped wherein patient restarted weekly Retacrit Epoetin Alfa shots in Jun2021, providing treatment dates: 07Jun2021, 14Jun2021, 21Jun2021, 28Jun2021, and 12Jul2021. The patient's hemoglobin level was 11.8 when quit getting his Retacrit Epoetin Alfa shots (in Apr2021). His hemoglobin level then dropped to 10.5 in Jun2021. It was clarified that his recent hemoglobin levels were 10.7 on 14Jun2021 and 10.5 on 21Jun2021. The event resulted to physician office visit. The outcome of the "Hemoglobin has dropped" was not recovered.  Follow-up attempts are completed. No further information is expected.