Bilateral pain in upper arms between bicep and humerus/Bilateral pain in fingers/Bilateral foot pain; Pain radiating to fingers; Arms turned red purple; Bulging veins in hands/arms; Pain/stiffness in all joints of fingers; Pain/stiffness in all joints of fingers; Feels like fingers are swollen; Fatigue; Flushing if touched or scratched; Randomly welt when scratched/pinched; numbness bilateral pinky/ring finger/ bilateral 4th/5th toes; Cold/numbness bilateral pinky/ring finger;  bilateral 4th/5th toes; Muscle twitches in lower extremities; Neuropathy (burning) toes/foot pads; Neuropathy (burning) toes/foot pads; Muscle stiffness/Bilateral Finger stiffness unable to flex fingers completely/bilateral foot stiffness; Muscle stiffness/soreness; Rash on L top knee 4 inches in diameter; bright red; Bilateral Muscle weakness in fingers; Developed Bilateral trigger finger in, pinky fingers; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from Regulatory Authority. The reporter is the patient.  A 53 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 23Apr2021 10:15 (Lot number: ER8725) at the age of 53 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Dysautonomia" (unspecified if ongoing); "pericarditis" (unspecified if ongoing); "pleural effusion pneumonia", start date: 2018 (unspecified if ongoing); "mononucleosis", start date: 1987 (unspecified if ongoing); "COVID" (unspecified if ongoing). There were no concomitant medications. Past drug history included: Known allergies: cipro, reaction(s): "known allergies: Cipro"; Known allergies: erythromycin, reaction(s): "known allergies: Erythromycin". The patient had not received any other vaccine in four weeks.   The following information was reported: PAIN IN EXTREMITY (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Bilateral pain in upper arms between bicep and humerus/Bilateral pain in fingers/Bilateral foot pain"; PAIN (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Pain radiating to fingers"; SKIN DISCOLOURATION (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Arms turned red purple"; VARICOSE VEIN (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Bulging veins in hands/arms"; ARTHRALGIA (disability), JOINT STIFFNESS (disability) all with onset 26Apr2021 21:00, outcome "not recovered" and all described as "Pain/stiffness in all joints of fingers"; PERIPHERAL SWELLING (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Feels like fingers are swollen"; FATIGUE (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Fatigue"; FLUSHING (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Flushing if touched or scratched"; URTICARIA (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Randomly welt when scratched/pinched"; HYPOAESTHESIA (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "numbness bilateral pinky/ring finger/ bilateral 4th/5th toes"; FEELING COLD (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Cold/numbness bilateral pinky/ring finger;  bilateral 4th/5th toes"; MUSCLE TWITCHING (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Muscle twitches in lower extremities"; NEUROPATHY PERIPHERAL (disability), BURNING SENSATION (disability) all with onset 26Apr2021 21:00, outcome "not recovered" and all described as "Neuropathy (burning) toes/foot pads"; MUSCULOSKELETAL STIFFNESS (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Muscle stiffness/Bilateral Finger stiffness unable to flex fingers completely/bilateral foot stiffness"; MYALGIA (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Muscle stiffness/soreness"; RASH ERYTHEMATOUS (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Rash on L top knee 4 inches in diameter; bright red"; MUSCULAR WEAKNESS (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Bilateral Muscle weakness in fingers"; TRIGGER FINGER (disability) with onset 26Apr2021 21:00, outcome "not recovered", described as "Developed Bilateral trigger finger in, pinky fingers". The events "bilateral pain in upper arms between bicep and humerus/bilateral pain in fingers/bilateral foot pain", "pain radiating to fingers", "arms turned red purple", "bulging veins in hands/arms", "pain/stiffness in all joints of fingers", "pain/stiffness in all joints of fingers", "feels like fingers are swollen", "fatigue", "flushing if touched or scratched", "randomly welt when scratched/pinched", "numbness bilateral pinky/ring finger/ bilateral 4th/5th toes", "cold/numbness bilateral pinky/ring finger;  bilateral 4th/5th toes", "muscle twitches in lower extremities", "neuropathy (burning) toes/foot pads", "neuropathy (burning) toes/foot pads", "muscle stiffness/bilateral finger stiffness unable to flex fingers completely/bilateral foot stiffness", "muscle stiffness/soreness", "rash on l top knee 4 inches in diameter; bright red", "bilateral muscle weakness in fingers" and "developed bilateral trigger finger in, pinky fingers" were evaluated at the physician office visit. It was unknown if therapeutic measures were taken as a result of pain in extremity, pain, skin discolouration, varicose vein, arthralgia, joint stiffness, peripheral swelling, fatigue, flushing, urticaria, hypoaesthesia, feeling cold, muscle twitching, neuropathy peripheral, burning sensation, musculoskeletal stiffness, myalgia, rash erythematous, muscular weakness, trigger finger. The patient reported pain/stiffness in all joints of fingers would come and go; and the rash on her knee was present for a couple days then returned for a couple of more days. She reported that 9-months post shot, she had the bilateral finger stiffness unable to flex fingers completely, bilateral muscle weakness in fingers, bilateral pain in fingers, fingers feels swollen, developed bilateral trigger finger in pinky fingers, bilateral foot pain/stiffness (foot pad). Since vaccination the patient had not been tested for COVID.