arm was swollen; arm was red; arm was itchy; This case was reported by a other health professional via other manufacturer and described the occurrence of swelling arm in a 69-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included hepatitis c (had hepatitis C about 13 to 14 years ago) and spinal fusion (Family History) (her mom had a back fusion years ago, probably before they even screened blood products). Previously administered products included covid-19 (received 1st dose on 8th February 2021). Concurrent medical conditions included eye disorder (she has a type of eye blindness, so she doesn't use computers.), memory disturbance (has some memory problems) and blood pressure. Concomitant products included COVID-19 VACCINE.   On an unknown date, the patient received Shingrix. On an unknown date, less than a year after receiving Shingrix and an unknown time after receiving COVID-19 VACCINE, the patient experienced swelling arm, erythema of extremities and itchy upper limbs. The patient was treated with ondansetron (Zofran), interferon, peginterferon alfa-2b + ribavirin (Pegatron) and alprazolam (Xanax). On an unknown date, the outcome of the swelling arm and erythema of extremities were unknown and the outcome of the itchy upper limbs was recovered/resolved.   It was unknown if the reporter considered the swelling arm, erythema of extremities and itchy upper limbs to be related to Shingrix.  Additional details provided were as follows: The case was reported by patient herself. The age at vaccination was not reported. The patient had historical condition of Hepatitis C about 13 to 14 years ago. The patient had current condition type of eye blindness, so she did not use computers and eye blindness occurred prior to receiving the vaccines. The patient reported that her arm was swollen, red and itchy after getting the Shingrix vaccine.  The patient stated that was a couple years ago and she did not had the Lot/NDC/Expiry to provide. The patient found that the card that was filled out when she got the Shingrix vaccine and her husband provided the dates written on the card that was received on 19th December 2021. They came back on 09th December 2020 and also had the date of 19th April 2021, but unknown what was this date. All dates verified with patient and her husband. The patient stated that she did not understand the dates because she thought she got the vaccine a couple years ago and she did get both doses from a drug store.  The patient stated that she would provide a picture of the card if requested. On 30th September 2021 around 9:30 to 10 am, patient received booster of Pfizer Covid 19 vaccine in left arm with lot number FC3184 and within a few hours she became violently ill.  She thought it would only last a few days, but it never left her.  She was currently 70 years old, but she was 69 years old when she had the booster.  Some of the side effects that she had were diarrhea and severe stomach cramps.  She had never felt that sick before.  The diarrhea and stomach cramps have subsided, but it took weeks.  Now, she felt like the vaccine had infiltrated her nervous system and she was so shaky and nervous, and felt like she could not exist in the world. The patient had been to 2 physician and one of them told her to go to the Emergency room (ER). While she was in the ER they tested all her major organs, and did bloodwork, and on paper she looked okay, everything came back fine, but she was very weak, had no strength. The patient stated that some days she could get up, get dressed, and do a few things, but when she did not that it completely wiped her out, then she had to lay down and she could not get back up the rest of the day.  The patient did not like to take medication, but she did not take blood pressure medication so she would take medication if she had too. The patient's physician gave her some medication because she felt like she was going to explode with anxiousness.  The physician gave her 0.5mg Xanax and she took it twice a day, and even with that the anxiousness was still unbearable, the shaking and anxious feeling.  It did not help for just a little while, but it did not last.  The product was in a brown pharmacy bottle, no Lot/NDC/Expiry was provided. The patient did not want any magic pills because she knew nothing would make this all just disappear, she just wanted Pfizer to be aware that this was happening. The patient reported that the diarrhea started within a few hours after getting the shot and lasted 3 to 4 days, but may had been a little longer because it was so bad that she had to get a medication for diarrhea from her physician. The patient's physician prescribed her a medication she thought was called Zofran, but then that made her constipated so she had to stop taking it.  The patient did not had the Zofran bottle with her to provide the Lot/NDC/Expiry.  The patient stated that she got the injection between 9:30 to 10am, and most all symptoms occurred that same evening.  The stomach cramps started the same day that she got the vaccine, but she was having some memory problems so she did not knew how long the stomach cramps lasted.  The patient stated that the stomach cramps were almost unbearable and she would rather had been in labor and been giving birth with no epidural.  They were not like regular stomach cramps. The patient did not had stomach cramps anymore.  The patient did not remember when the shaky and nervousness started.  The patient did remember her arm itched like crazy from the injection site on her left arm all the way down to her elbow for weeks; started the same day as the injection.  She felt so ill, worse than she would have felt if she had the flu.  The patient stated that she could not even find the words to describe how awful she felt, and she had such extreme weakness.  She lost her appetite for a long time.  The patient stated that she could not stand the thought of having to eat, but she knew that she had to eat or she would just get sicker, so she forced herself to had small bites of food, and that lasted for over a month and it started the day she got the shot.  The patient never had this problem before. Prior to getting the booster shot, she was very active and walked fast and was just an extremely active person before all this, and since the vaccine she did not even recognize herself. The patient wished someone would just tell her, maybe they did not want this to get out because it would deter people from getting the vaccine. The patient stated that she was still pro vaccine, but if someone could just tell her when it would wear off or if she was going to had to deal with this for the rest of her life, because the not knowing was making this more difficult.  The patient was smart enough to knew that this was all new, and maybe people just did not knew, but she was just frustrated.  The patient stated that she was calling because she just wanted it to be documented in case it happened to anyone else.  The patient stated that she knew several people that had reactions, but they had only lasted several days.  No further details was provided. The patient reported that when she went to the ER they tested all her major organs, heart, kidneys, liver, and did bloodwork and on paper she looked okay and everything came back fine. She was never a drug user and she used to be a phlebotomist and a dental assistant back before anyone used gloves, but it was an unsolved mystery as to how she got the hepatitis C. She was taking Interferon and Pegatron combination injections, and she was supposed to take 24 injections, but she only made it to 16 because she became so ill from the medication that her priest gave her the last sacraments.  The patient's liver test was done and all the time and the Hepatitis C had never come back, but her mom died with Hepatitis C. The patient stated that her mom had a back fusion years ago, probably before they even screened blood products.  The patient stated that now one of her biggest fears was taking any medications because of the effects on her liver.  The patient's physician wanted to gave her something for anxiety that started with a C because it would have lasted in her body for 12 hours, but it flagged in the system that it could be bad for her liver, so he had to give her the Xanax instead.  The patient stated that she was not upset with anyone, this was no one's fault, she just had reactions, or maybe it's just her DNA.  The patient did not knew who could advise her on whether she should take vaccines for Covid again. The patient thought she would had done better taking her chances with the Covid instead of getting the vaccine.  The patient stated that she remembered something else and about a year ago, during her regular mammogram, they found a cluster of calcifications in her left breast.  They did a biopsy and made another appointment to have it rechecked; that appointment was 2 to 3 weeks ago. She told herself to just go and get it done with, but didn't tell them how she was feeling when she got there.  It was through stated that when they did the compression on her breast, she almost passed out.  They gave her ice for the back of her neck because they could see that she was weak, and when she tried to stand back up her legs were like jelly.  The patient stated that when she did not had to think about it, but her legs were not listening to her brain because of the shakiness.  They brought her out to her husband, but her legs still did not feel right and it was an odd feeling. The patient stated that it was almost her sister's birthday, so she wanted to go into the store. She told her husband to drop her off at the door and to go park the car.  The patient stated that as soon as she walked into the store she hit the floor.  Her husband had to go back to get the car and they just went home. The patient stated that before she left she asked the nurse what could have caused her to almost pass out and make her legs feel like that and the nurse asked if she had any kind of nerve damage.  The patient stated that and she told the nurse no, not that she knew of, but that really freaked her out, that her legs were not listening to her body.  The reporter consented to follow-up.