Multiple necrotic black lesions on both sides of Vulva  days after 2nd primary shot/Doctor stated it may be Cancer on vulva  after 2nd primary dose; Vaginal Discomfort 2 days after 2nd primary shot/Worst Vaginal Discomfort 3 days after 2nd primary shot; Felt bad again 1  day after 2nd primary shot; Vaginal hurt down there 1  day after 2nd primary shot; Developed aches 10 Hours after 2nd primary shot; Similar to Flu symptoms 10 Hours after 2nd primary shot; Fever 10 Hours after 2nd primary shot; Fatigue 10 Hours after 2nd primary shot; This spontaneous case was reported by a nurse and describes the occurrence of PAIN (Developed aches 10 Hours after 2nd primary shot), INFLUENZA LIKE ILLNESS (Similar to Flu symptoms 10 Hours after 2nd primary shot), FEELING ABNORMAL (Felt bad again 1  day after 2nd primary shot), VULVOVAGINAL PAIN (Vaginal hurt down there 1  day after 2nd primary shot) and VULVOVAGINAL DISCOMFORT (Vaginal Discomfort 2 days after 2nd primary shot/Worst Vaginal Discomfort 3 days after 2nd primary shot) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 030L20A and 025J20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 23-Dec-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 20-Jan-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 20-Jan-2021, the patient experienced PAIN (Developed aches 10 Hours after 2nd primary shot), INFLUENZA LIKE ILLNESS (Similar to Flu symptoms 10 Hours after 2nd primary shot), PYREXIA (Fever 10 Hours after 2nd primary shot) and FATIGUE (Fatigue 10 Hours after 2nd primary shot). On 21-Jan-2021, the patient experienced FEELING ABNORMAL (Felt bad again 1  day after 2nd primary shot) and VULVOVAGINAL PAIN (Vaginal hurt down there 1  day after 2nd primary shot). On 22-Jan-2021, the patient experienced VULVOVAGINAL DISCOMFORT (Vaginal Discomfort 2 days after 2nd primary shot/Worst Vaginal Discomfort 3 days after 2nd primary shot). On 23-Jan-2021, the patient experienced VULVAL DISORDER (Multiple necrotic black lesions on both sides of Vulva  days after 2nd primary shot/Doctor stated it may be Cancer on vulva  after 2nd primary dose). The patient was treated with IBUPROFEN at an unspecified dose and frequency. At the time of the report, PAIN (Developed aches 10 Hours after 2nd primary shot), INFLUENZA LIKE ILLNESS (Similar to Flu symptoms 10 Hours after 2nd primary shot), FEELING ABNORMAL (Felt bad again 1  day after 2nd primary shot), VULVOVAGINAL PAIN (Vaginal hurt down there 1  day after 2nd primary shot), VULVOVAGINAL DISCOMFORT (Vaginal Discomfort 2 days after 2nd primary shot/Worst Vaginal Discomfort 3 days after 2nd primary shot), VULVAL DISORDER (Multiple necrotic black lesions on both sides of Vulva  days after 2nd primary shot/Doctor stated it may be Cancer on vulva  after 2nd primary dose), PYREXIA (Fever 10 Hours after 2nd primary shot) and FATIGUE (Fatigue 10 Hours after 2nd primary shot) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication was reported.  Patient consulted to doctor, Doctor stated it may be Cancer. Doctor did STD panels and gave 2 weeks of Steroids and cold packs and warm packs. Autoimmune test panels done. All tests were within normal limits.   This case was linked to MOD-2022-654969, MOD-2022-654973 (Patient Link).