Acute sinusitis; felt this hoarse/ two damaged throat; Vocal cord are fine but you have so much fluid around them is why you cannot speak; my hair still isn't grown big, it is getting really bad, just falling out; my hair still isn't grown big, it is getting really bad, just falling out; Very painful; blood pressure went high; My heart rate went up so bad; hyperthyroidism; I wondered losing my weight; lost my voice/ cannot talk/ did not have a voice; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 36-year-old female patient received BNT162b2 (BNT162B2), in Sep2021 as dose 2, single (Batch/Lot number: unknown) at the age of 36 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "I do not drink any alcohol never have" (unspecified if ongoing); "I never smoked or anything" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: BNT162b2 (Dose 1, single), administration date: 13Aug2021, when the patient was 36-year-old, for COVID-19 Immunization, reaction(s): "After getting vaccinated I kept having more frequent bowel movement; I would eat something or as soon as it with hit the bottom of my  stomach, I have to go to use the bathroom". The patient drink lots of water, do not drink any alcohol never have, never smoked or anything and was very healthy. The following information was reported: APHONIA (non-serious) with onset Sep2021, outcome "recovered" (May2022), described as "lost my voice/ cannot talk/ did not have a voice"; WEIGHT DECREASED (non-serious) with onset Oct2021, outcome "unknown", described as "I wondered losing my weight"; HYPERTHYROIDISM (medically significant) with onset 22May2022, outcome "unknown"; ACUTE SINUSITIS (non-serious), outcome "unknown"; DYSPHONIA (non-serious), outcome "unknown", described as "felt this hoarse/ two damaged throat"; VOCAL CORD DISORDER (non-serious), outcome "unknown", described as "Vocal cord are fine but you have so much fluid around them is why you cannot speak"; HAIR GROWTH ABNORMAL (non-serious), ALOPECIA (non-serious), outcome "unknown" and all described as "my hair still isn't grown big, it is getting really bad, just falling out"; PAIN (non-serious), outcome "unknown", described as "Very painful"; HYPERTENSION (non-serious), outcome "unknown", described as "blood pressure went high"; HEART RATE INCREASED (non-serious), outcome "unknown", described as "My heart rate went up so bad". The events "hyperthyroidism", "acute sinusitis", "felt this hoarse/ two damaged throat" and "my hair still isn't grown big, it is getting really bad, just falling out" required physician office visit. The event "my heart rate went up so bad" required emergency room visit. The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (unspecified date) blood pressure went high, notes: after getting vaccine my blood pressure went high; Blood test: (Sep2021) something seemed off, notes: may be like with my hormones or something; Heart rate: (unspecified date) My heart rate went up so bad; I am actually died; Test/ lab work: (unspecified date) she tests me it was not losing all of this is, notes: hyper side effect and I found it out because on 23May; (Nov2021) did not have diabetes; (Jul2023) Unknown results; Thyroid function test: (unspecified date) My thyroid level was so low that it was undetectable, notes: My thyroid level was so low that it was undetectable; asymptomatic all of that is hyperthyroidism; Ultrasound scan: (unspecified date) Unknown results. Therapeutic measures were taken as a result of hyperthyroidism, acute sinusitis, dysphonia, hair growth abnormal, alopecia, hypertension including Atenolol take 25 mg, takes one tablet by mouth every day and Methimazole 10 mg tablet one tablet by mouth twice a day.   Clinical course: the patient got the second dose in Sep2021 and start happening but the covid number was so high she did not really wait, patient had a physical schedule to with primary care manager in Sep2021 and so what she said is that she was concerned about her hormone that she said something seemed off and she thought that patient may have diabetes but she is not going to give her the test for those three months and will see if she have diabetes so patient did these 3 tests in Nov it was determined that she did not have diabetes but she believe that was onset of the reaction from the second vaccine because right after that she lost my voice for 7 whole months and imagine trying to call service members. Finally like she was going to go to a doctor. It was like Feb2022 and she was just going to go because it was kind of because covid numbers were so high she was just trying to get it okay she have to go because obviously something is wrong. Okay. In Oct 2021 in there she wondered losing weight, I mean cord for 7 whole months like literally and so she was like okay she do not know what this is but her body feels okay, she just cannot talk, then finally in Feb2022. She try not to go to the doctor during the winter because she did not wanted to get COVID but now she need to go to COVID because it is something going on with her sinus or something is not right, so she went to Withheld and they diagnosed me with Acute sinusitis and they gave her a Z-Pak. took the Z-Pak, they said they referred me to an ENT specialist because she felt this hoarse that she did not have a voice even then and went to ENT specialist they checked the two damaged throat because they through nose and throat, they wanted to see what is going on with vocal cord because she still could not talk and he said vocal cord are fine but have so much fluid around them that is why she cannot speak, meanwhile it went to her hair came out, she have not yet feel, not grown till day, it is only an inch long when it used to be like shoulder or whatever and she have to go through the dermatologist, she had to get scalp injection (Name could not be specified hence, captured as Unspecified medication) for like 6 month they do not numb your scalp, they because eventually if you get it straight it but that was very painful so, that also was expected to get done and again her hair still isn't grown big, it is getting really bad, just falling out and the dermatologist said she saw she had lose it because of the way she has grown my hair and it just came on her hand though she tests her it was not losing all of this is hyper side effect and patient found it out because on 23May. Patient went to patient for once again but on 22May2022 she was at church and the lady said did you met her, this is her and I said no why she said it is rolling because it is checked out, she said okay well I will go tomorrow so, on Monday 23May2022 she went to patient first and was told that her thyroid level or TSH (Thyroid stimulating hormone) or whatever it was so low that it was undetectable, so they had put her on medication, she had to take Methimazole (Treatment), twice a day and then so, she said I am just going to give you the COVID test too just for the safer because I was at low, if I have been hoarse for 7 months what the doctor said no, she said you are actually asymptomatic he was like okay, all of that is hyperthyroidism, none of this is happening after she got vaccinated she never had high blood pressure in her life even she was pregnant and gave to birth, she never had gestational diabetes anything even about in 2017, so all of a sudden after getting vaccine her blood pressure went high, she lost her voice and it eventually came back but it took forever so any way, going back to May2022 so, she guess her tested positive for COVID went by 27May by end of that week she found herself in the back of an ambulance, on the way to the ER (Emergency Room) because her heart rate went up so bad that she thought she was actually died.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300289436 same patient/drug, different dose/event;