Blood clot/[heart] that's where the clot was; started kind of mild/it got worse after the second dose/mild chest pain; This spontaneous case was reported by a consumer and describes the occurrence of THROMBOSIS (Blood clot/[heart] that's where the clot was) in a 67-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 022C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 06-May-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In May 2021, the patient experienced CHEST PAIN (started kind of mild/it got worse after the second dose/mild chest pain). On an unknown date, the patient experienced THROMBOSIS (Blood clot/[heart] that's where the clot was) (seriousness criterion medically significant). The patient was treated with ASPIRIN [ACETYLSALICYLIC ACID] for Adverse event, at a dose of 1 dosage form; TICAGRELOR (BRILINTA) for Adverse event, at a dose of 1 dosage form and Surgery for Thrombosis. At the time of the report, THROMBOSIS (Blood clot/[heart] that's where the clot was) and CHEST PAIN (started kind of mild/it got worse after the second dose/mild chest pain) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant product was not provided by the reporter The patient states her chest pain started kind of mild and got worse after the second dose. She thought it was muscular, even up till June. In July, it got worse and the patient felt sharp pain and touched her heart, and that's where the clot was. Patient got for a digital stress test and went to the hospital on 15-Jul-2021. Patient had a blood clot, and had a surgery with the clot dissolved and a stent placed in. Sometime in August, she had sharp pain. Patient went back to  doctor on 11-Oct-2021 and another test done on 25-Oct-2021, but they didn't see anything. Patient stated that  pain has continued, but it's just been mild. Patient had experienced, after they removed the clot, it stayed sore. Patient was feeling Scared to move, sharp pain and he was lying in bed  Company comment- This case concerns a 67-year-old, female patient with no medical history, reported, who experienced the unexpected events of chest pain and thrombosis. The events occurred approximately 3 months after the second dose of mRNA-1273. The patient had a chest pain which started kind of mild but then became sharp and the patient touched her heart where the clot was. Patient had a blood clot, and had a surgery with the clot dissolved and a stent placed in. After surgery patient again experienced chest pain which continued as mild. The rechallenge was not applicable as events occurred following second dose and no further dosing was planned based on information available. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2021-385956 (Patient Link).; Sender's Comments: This case concerns a 67-year-old, female patient with no medical history, reported, who experienced the unexpected events of chest pain and thrombosis. The events occurred approximately 3 months after the second dose of mRNA-1273. The patient had a chest pain which started kind of mild but then became sharp and the patient touched her heart where the clot was. Patient had a blood clot, and had a surgery with the clot dissolved and a stent placed in. After surgery patient again experienced chest pain which continued as mild. The rechallenge was not applicable as events occurred following second dose and no further dosing was planned based on information available. The benefit-risk relationship of mRNA-1273 is not affected by this report.