weakened immune system; Pityriasis rubra pilaris; In Apr, the places of my face were getting bigger; In Apr, the places of my face were getting redder; Skin began drying; Skin began flaking; Rash/ The places began to spread across my face forehead, cheeks, then to chest; My body displayed eczema or psoriasis; My body displayed eczema or psoriasis; contact dermatitis/The places began to spread across my face forehead, cheeks, then to chest; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A patient (no qualifiers provided) received bnt162b2 (BNT162B2), administered in arm, administration date 24Mar2021 15:00 (Lot number: EP6955) at the age of 70 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "rheumatoid arthritis", start date: 2014 (unspecified if ongoing), notes: diagnosed with moderate rheumatoid arthritis. There were no concomitant medications. Past drug history included: Humira, notes: In 2016/2017 I started using Humira instead of methotrexate. Vaccination history included: Bnt162b2 (Dose 1, Time: 15:00, Anatomical site of injection: arm, Batch/lot number: EN6205), administration date: 03Mar2021, for Covid-19 Immunization. The following information was reported: SWELLING FACE (non-serious) with onset Apr2021, outcome "unknown", described as "In Apr, the places of my face were getting bigger"; ERYTHEMA (non-serious) with onset Apr2021, outcome "unknown", described as "In Apr, the places of my face were getting redder"; DRY SKIN (non-serious) with onset 2021, outcome "unknown", described as "Skin began drying"; SKIN EXFOLIATION (non-serious) with onset 2021, outcome "unknown", described as "Skin began flaking"; RASH (non-serious) with onset 2021, outcome "unknown", described as "Rash/ The places began to spread across my face forehead, cheeks, then to chest"; ECZEMA (non-serious), PSORIASIS (non-serious) all with onset 2021, outcome "unknown" and all described as "My body displayed eczema or psoriasis"; DERMATITIS CONTACT (non-serious) with onset 2021, outcome "unknown", described as "contact dermatitis/The places began to spread across my face forehead, cheeks, then to chest"; PITYRIASIS RUBRA PILARIS (non-serious) with onset Jan2022, outcome "unknown", described as "Pityriasis rubra pilaris"; IMMUNE SYSTEM DISORDER (non-serious), outcome "unknown", described as "weakened immune system". The events "in apr, the places of my face were getting bigger", "in apr, the places of my face were getting redder", "skin began drying", "skin began flaking", "rash/ the places began to spread across my face forehead, cheeks, then to chest", "my body displayed eczema or psoriasis", "my body displayed eczema or psoriasis", "contact dermatitis/the places began to spread across my face forehead, cheeks, then to chest", "pityriasis rubra pilaris" and "weakened immune system" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of swelling face, erythema, dry skin, skin exfoliation, rash, eczema, psoriasis, dermatitis contact, pityriasis rubra pilaris, immune system disorder.  Additional information: Prior vaccination (within 4 weeks) was reported as none. Relevant test taken was none. Specific relevant test for thromboembolic events with thrombocytopenia was none. In 2014 patient was diagnosed with moderate rheumatoid arthritis. In 2016/2017 patient started using Humira instead of methotrexate. In Feb2021 patient developed several places of my face that patient made appointment with dermatologist on 09Mar2021. Prior to that 03Mar2021 patient got first vaccine shot. The dept prescribed a ointment, on 24Sep2021. Patient received second shot. In April the places of patient's face were getting bigger, redder. Back to dermatologist. More creams and ointments. Biopsies showed contact dermatitis. The places began to spread across patient's face forehead, cheeks, then to chest. Skin began drying and flaking. Patient's body displayed eczema or psoriasis. Prednisone was prescribed during Apr and May. It helped but just exploded once off the medicines. Did patch test to find a allergy to soap preservative. Eliminated the chemical. The rash continued all year with 3 prednisone treatments Dec2021 the last use of prednisone. Jan2022 patient's Doctor finally determined using prednisone. Patient had a psoriasis called Pityriasis rubra pilaris and acitretin it is helping patient believe that immune system tried to work against the vaccine drainage mate. Patient had weakened immune system. Patient used medications that suppress the immune system (e.g., high-dose of corticosteroids, cyclosporine, methotrexate, azathioprine, and biologic therapies like rituximab and etanercept). Patient received third dose (Batch number: EW0171) on 17Aug2021 at 11:30, administered in arm.  Follow-up attempts are completed. No further information is expected.