She had their like hives, it started out on her neck very red, very swollen and then it  started going to the left side of her face, and then it started to appear on her neck hives; This is not getting better now the injection site which is not bothered her until today, is started she get red, a little swollen and she itches everywhere, she is miserable; She had their like hives, it started out on her neck very red, very swollen and then it  started going to the left side of her face, and then it started to appear on her neck hives; She had their like hives, it started out on her neck very red, very swollen and then it  started going to the left side of her face, and then it started to appear on her neck hives; This is not getting better now the injection site which is not bothered her until today, is started she get red, a little swollen and she itches everywhere, she is miserable; This is not getting better now the injection site which is not bothered her until today, is started she get red, a little swollen and she itches everywhere, she is miserable; This is a spontaneous report from a contactable consumer. This consumer reported for a 80-year-old female patient that: An 80-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Left on 22Jul2021 (Batch/Lot Number: FA6780) (at the age of 80-years-old ) as single dose for covid-19 immunization. The patient had received the first dose of bnt162b2 on 01Jul2021. Medical history included hypertension and hypothyroidism from an unknown date and unknown if ongoing. Concomitant medication(s) included levothyroxine (LEVOTHYROXINE) 112 mcg take once by mouth every morning on empty stomach taken for thyroid disorder, start and stop date were not reported and lisinopril (LISINOPRIL)  10 mg taken for hypertension, start and stop date were not reported.  The consumer reported that the mother has had an allergic reaction or some sort of reaction to the second dose of Pfizer vaccine, she did not have one at all with the first dose, she had their like hives, it started out on her neck very red, very swollen and then it started going to the left side of her face, and then it started to appear on her neck hives, that's what we thought it was and then she went to her family doctor and he put her on around a steroids not topical oral, an antihistamine  and antibiotic. A week later, she wasn't feeling any better and in fact they were spreading so she went to the ER, would have been a week ago today and there she was hoping to get a cortisone shot and they do not gave cortisone shot in ER. She does got to dermatologist so, she called and get into him that this past two days and he is the one to tell that she is having a reaction to the COVID shot but ER put her on another round of steroids and cortisone cream and I can't remember the another one, dermatologist and he is the one that believe that, she had a reaction to the second shot because it was 5 days after second shot, that she started with on her neck, this is not getting better now the injection site which is not bothered her until today, is started she get red and a little swollen and she itches everywhere, she is miserable  and they don't know what to do next, because it doesn't seem anybody taking it seriously. Recently she was on her Prednisone 20 mg for steroids orally and this one is the second round 20 mg take one tablet by mouth for seven day, Friday. She also put on Hydroxyzine for itching at 25 mg one capsule by mouth 3 times a day as per needed for itching. Cetirizine, 10 mg one tablet by mouth every day. The consumer reported that none of the medicines that they have given her, the steroids, the antihistamine, the topical cream nothing is working. It's worse. The outcome of the events was not recovered.  Follow-up attempts are completed. No further information is expected.