Received Pfizer-BioNTech COVID-19 Vaccine first dose in 2020/second dose of Pfizer-BioNTech COVID-19 Vaccine on 15Sep2022; Chest pain; left side of the face numbness happened only one time/Numbness happened one time; Numbness happened one time with tingling down her arm; Fatigue/Tired; Shortness of breath; Chest pounding; Chest discomfort; Very weak tired; She is not feeling normal at all/feeling like in a daze; upset/stress; Anxiety; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A female patient received BNT162b2 (BNT162B2), on 15Sep2022 as dose 2, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "Psoriasis" (unspecified if ongoing), notes: she had to take her medications mentioned psoriasis from head to toe. Concomitant medication(s) included: COSENTYX. Vaccination history included: Bnt162b2, for COVID-19 Immunization, reaction(s): "Chest pain". The following information was reported: ANXIETY (non-serious) with onset 2022, outcome "unknown"; CHEST DISCOMFORT (non-serious) with onset Sep2022, outcome "unknown"; CHEST PAIN (non-serious) with onset Sep2022, outcome "unknown"; PALPITATIONS (non-serious) with onset Sep2022, outcome "unknown", described as "Chest pounding"; FATIGUE (non-serious) with onset Sep2022, outcome "unknown", described as "Fatigue/Tired"; PARAESTHESIA (non-serious) with onset Sep2022, outcome "unknown", described as "Numbness happened one time with tingling down her arm"; INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (non-serious) with onset 15Sep2022, outcome "unknown", described as "Received Pfizer-BioNTech COVID-19 Vaccine first dose in 2020/second dose of Pfizer-BioNTech COVID-19 Vaccine on 15Sep2022"; FEELING ABNORMAL (non-serious) with onset Sep2022, outcome "unknown", described as "She is not feeling normal at all/feeling like in a daze"; DYSPNOEA (non-serious) with onset Sep2022, outcome "unknown", described as "Shortness of breath"; ASTHENIA (non-serious) with onset Sep2022, outcome "unknown", described as "Very weak tired"; HYPOAESTHESIA (non-serious) with onset Sep2022, outcome "unknown", described as "left side of the face numbness happened only one time/Numbness happened one time"; STRESS (non-serious) with onset Sep2022, outcome "unknown", described as "upset/stress". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Caller wanted to know if being on Cosentyx affects the effectiveness of the Pfizer-BioNTech COVID-19 Vaccine as caller taking Cosentyx monthly. Caller stated that she was forced to get a COVID shot she was a housekeeper. Later on caller stated that she received Pfizer-BioNTech COVID-19 Vaccine first dose in 2020 (reported chest pain once after first dose) and second dose of Pfizer-BioNTech COVID-19 Vaccine on 15Sep2022 caller stated that she is waking up at 2 AM with chest pain ,left side of the face numbness happened only one time numbness happened one time with tingling down her arm, fatigue, tired she is going to see a doctor, Reported shortness of breath , chest pounding when she wakes up she notices that her chest is pounding really hard and it is pain, discomfort, very weak tired feeling like in a daze, Mentioning that she had to take her medications mentioned psoriasis from head to toe, mentioned that her bloodwork came back normal but she is not feeling normal at all, especially in her chest, caller stated that she was very upset , hoping that her heart would be ok, caller stated that she was upset with everything and putting more stress on her heart.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.