Haven't felt good for weeks; Eyes have red circles around them; It hurts to much to rub eyes; Eyes started itching badly; Rashes appeared on neck, chest, back, leg,bad rashes; Very itchy, itching terribly bad; Lotion burns; Head hurts; Ill overnight; This non-serious case was reported by a consumer and described the occurrence of unwell in a 59-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Flu unspecified (Flu vaccine) for prophylaxis, PNEUMOCOCCAL VACCINE (PNEUMONIA VACCINE) for prophylaxis and COVID-19 VACCINE for prophylaxis.   Concurrent medical conditions included basal cell carcinoma (basil skin cancer). Concomitant products included gabapentin, oxycodone + paracetamol (Acetaminophen + Oxycodone), fluoxetine, tizanidine and tolterodine. Family history included shingles (patient's mother, extremely bad, had 5year ago) and acquired immunodeficiency syndrome (patient's brother).   On 15-FEB-2023, the patient received Shingrix, Flu vaccine, PNEUMONIA VACCINE and COVID-19 VACCINE. On 15-FEB-2023, less than a day after receiving Shingrix and Flu vaccine, the patient experienced unwell (Verbatim: Ill overnight). On 21-FEB-2023, the patient experienced eye pruritus (Verbatim: Eyes started itching badly), generalized rash (Verbatim: Rashes appeared on neck, chest, back, leg,bad rashes), pruritus (Verbatim: Very itchy, itching terribly bad), burning sensation (Verbatim: Lotion burns) and headache (Verbatim: Head hurts). On an unknown date, the patient experienced feeling bad (Verbatim: Haven't felt good for weeks), erythema (Verbatim: Eyes have red circles around them) and pain (Verbatim: It hurts to much to rub eyes). The outcome of the unwell, feeling bad, erythema and pain were not reported and the outcome of the eye pruritus, generalized rash, pruritus, burning sensation and headache were not recovered/not resolved.   It was unknown if the reporter considered the unwell, eye pruritus, generalized rash, pruritus, burning sensation, headache, feeling bad, erythema and pain to be related to Shingrix and Flu vaccine.     It was unknown if the company considered the unwell, eye pruritus, generalized rash, pruritus, burning sensation, headache, feeling bad, erythema and pain to be related to Shingrix and Flu vaccine.   Additional Information: GSK Receipt Date: 19-MAR-2023  The Patient is the reporter. The patient dates for had injection with 3 others (vaccine : COVID, Flu, Pneumonia) and was ill overnight. 6 days later, patient's eyes started itching badly, then rashes appeared on neck, chest, back, leg, very itchy, lotion burns, head hurts. Patient stated that he/she  see dermatologist in 3 days due to unrelated basil skin cancer and seeing these bad rashes occur and not knowing what they were. Mother of patient had Shingles 5 years ago and it was extremely bad for her. Mother insists it is Shingles but the pharmacist says it cannot be. Patient is itching terribly bad and haven't felt good for weeks. Patient's eyes have red circles around them and it hurts to much to rub them anymore. Patient is continuously putting drops in them.  Patient states that he/she don't know if it's shingles and if it's catchy.  Patient's brother has AIDS and has never had chicken pox. Patient had already hugged him last week so he/she is nervous.  The symptoms were not treated.  Patient provided his/her details and consented to followup. This report was submitted via the online direct entry reporting system. 6 day after receiving Shingrix and Flu vaccine the patient experienced eye pruritus, generalized rash, pruritus, burning sensation and headache.  It was unknown if the reporter considered the unwell, eye pruritus, generalized rash, pruritus, burning sensation, headache, feeling bad, erythema and pain to be related to PNEUMOCOCCAL VACCINE (PNEUMONIA VACCINE) and COVID-19 VACCINE.