This spontaneous case was reported by a consumer and describes the occurrence of INFLUENZA LIKE ILLNESS (had flu-like symptoms with first two doses, flu-like syndrome), FEELING ABNORMAL (feeling terrible for over a week with each shot) and SKIN LESION (lesion on his left upper back has been present intermittently) in a 38-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 037B21A and 026A21A) for COVID-19 vaccination. The patient's past medical history included Smoker (0.5 packs day, Smokeless Tobacco Never Used. Patient quit 18 years ago). Family history included CVA (Paternal Grandfather), Type 2 diabetes mellitus, Crohn's (sister), Eczema (son), Peanut allergy (son) and Bipolar disorder (mother). Concurrent medical conditions included Hyperlipidemia (Improvement, under control with diet and medication) since 01-Sep-2002, Hypertension (Improvement, under control with diet and medication) since 01-Jan-2015, Post-traumatic stress disorder (Improvement, under control with psychotherapy and medication) since 01-Sep-2006, GERD (Improvement, under control with diet and medication) since 01-Jan-2006, Anxiety (Improvement, under control with psychotherapy and medication) since 01-Sep-2006, Alcohol use, Major depressive disorder and Bone pain since 06-Jan-2021. Concomitant products included OMEPRAZOLE from 01-Jan-2006 to an unknown date for GERD, ATORVASTATIN from 01-Jan-2015 to an unknown date for Hyperlipidemia, AMLODIPINE from 01-Jan-2015 to an unknown date for Hypertension, SERTRALINE from 01-Jun-2019 to an unknown date for Post-traumatic stress disorder, ALPRAZOLAM from 01-Jun-2019 to an unknown date for Post-traumatic stress disorder and Anxiety. On 19-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 16-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In May 2021, the patient experienced SKIN LESION (lesion on his left upper back has been present intermittently). In 2021, the patient experienced INFLUENZA LIKE ILLNESS (had flu-like symptoms with first two doses, flu-like syndrome) and FEELING ABNORMAL (feeling terrible for over a week with each shot). At the time of the report, INFLUENZA LIKE ILLNESS (had flu-like symptoms with first two doses, flu-like syndrome), FEELING ABNORMAL (feeling terrible for over a week with each shot) and SKIN LESION (lesion on his left upper back has been present intermittently) outcome was unknown. Not Provided. For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments. Patient had no known active allergies. Patient had denied any family history of angioedema and medication changes. Patient was alcohol user and had 1 standard drink 0.6 oz. pure alcohol Drinks 1-2 glasses every other week. Frequency 3.0 times per week. Types: Marijuana which helped with anxiety, per patient, and he preferred it to Xanax. Patient father was relatively healthy, only with diet controlled DM. No inflammatory arthropathy he was aware of in the family. Patient had deep bone pain in hands which was maximum of 3 out of 10 on pain scale but seemed like different kind of pain than the previously presented symptoms. It was also reported that patient was feeling terrible for over the week with each shot but did not recall any urticaria or anything else resembling the current episode. No treatment medication was provided by the reporter. This case was linked to MOD-2022-498332, MOD-2022-445640 (Patient Link).