hand were swollen; oozing liquid; abdominal pain; could not walk; entire body was painful; felt horrible; legs were numb; serious headaches; chilly; very tired; fever of 103 degree Fahrenheit; vomiting; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PERIPHERAL SWELLING (hand were swollen), DISCHARGE (oozing liquid), ABDOMINAL PAIN (abdominal pain), GAIT INABILITY (could not walk), PAIN (entire body was painful), FEELING ABNORMAL (felt horrible), HYPOAESTHESIA (legs were numb), HEADACHE (serious headaches), CHILLS (chilly), FATIGUE (very tired), PYREXIA (fever of 103 degree Fahrenheit) and VOMITING (vomiting) in a 33-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 044B21A) for COVID-19 vaccination.     No Medical History information was reported.   On 30-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Apr-2021, the patient experienced PERIPHERAL SWELLING (hand were swollen) (seriousness criterion hospitalization), DISCHARGE (oozing liquid) (seriousness criterion hospitalization), ABDOMINAL PAIN (abdominal pain) (seriousness criterion hospitalization), GAIT INABILITY (could not walk) (seriousness criterion hospitalization), PAIN (entire body was painful) (seriousness criterion hospitalization), FEELING ABNORMAL (felt horrible) (seriousness criterion hospitalization), HYPOAESTHESIA (legs were numb) (seriousness criterion hospitalization), HEADACHE (serious headaches) (seriousness criterion hospitalization), CHILLS (chilly) (seriousness criterion hospitalization), FATIGUE (very tired) (seriousness criterion hospitalization), PYREXIA (fever of 103 degree Fahrenheit) (seriousness criterion hospitalization) and VOMITING (vomiting) (seriousness criterion hospitalization). The patient was hospitalized for 2 days due to ABDOMINAL PAIN, CHILLS, DISCHARGE, FATIGUE, FEELING ABNORMAL, GAIT INABILITY, HEADACHE, HYPOAESTHESIA, PAIN, PERIPHERAL SWELLING, PYREXIA and VOMITING. At the time of the report, PERIPHERAL SWELLING (hand were swollen), DISCHARGE (oozing liquid), ABDOMINAL PAIN (abdominal pain), GAIT INABILITY (could not walk), PAIN (entire body was painful), FEELING ABNORMAL (felt horrible), HYPOAESTHESIA (legs were numb), HEADACHE (serious headaches), CHILLS (chilly), FATIGUE (very tired), PYREXIA (fever of 103 degree Fahrenheit) and VOMITING (vomiting) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 30-Apr-2021, Body temperature: high 103 degrees.         No relevant concomitant medications were reported  Patient treated with antibiotics and refers having had a reaction to them.   Action taken with mRNA-1273 in response to the event was not applicable.  Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Patient referred having a reaction to the antibiotics which could be a confounder for prolonging her stay in the hospital.   This case was linked to MOD-2021-127756 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Patient referred having a reaction to the antibiotics which could be a confounder for prolonging her stay in the hospital.