she drank four glasses of water that day and four bubbly water cans that were 12 ounces each; any movement was painful; muscles in arms and legs began cramping/spasms and cramping; higher than normal blood sugar ranged between 200-300; able to sleep 20-30 mins at a time/wake up due to cold/shaking and body pain; her muscles and joints would not work; she could feel blood running through her body, it was pulsating and thought blood was going to burst through her head. She felt like her blood pressure was so high; a new pain in her legs that she would get hot spots,her legs would seize in a convulsive pain; felt like she was dying/feel blood rushing through body; stiffness then turned to pain that moving was excruciating all over even her wrist hurt, her elbow hurt to bend/body sore; felt like a truck hit her as she was exhausted/exhausted; major chill,shivering/shivering/shaking of limbs from being so cold; headache/pulsating and pounding in head/felt like top of head would explode off; very stiff,she felt like she was an 80-85 year old in how she was going down the steps because she was so stiff/body began to feel stiff; overwhelmingly cold feeling,shivering visibly/extremely cold; can feel her body like it is not wanting to continue to move,could hardly change from her street clothes to her pajamas/very difficult to get up and move around/could barely move legs to get out of vehicle; her muscles and joints would not work; This spontaneous case was reported by a consumer and describes the occurrence of MUSCULOSKELETAL STIFFNESS (very stiff,she felt like she was an 80-85 year old in how she was going down the steps because she was so stiff/body began to feel stiff), FEELING COLD (overwhelmingly cold feeling,shivering visibly/extremely cold), MOBILITY DECREASED (can feel her body like it is not wanting to continue to move,could hardly change from her street clothes to her pajamas/very difficult to get up and move around/could barely move legs to get out of vehicle), MUSCLE DISCOMFORT (her muscles and joints would not work) and HYPERTENSION (she could feel blood running through her body, it was pulsating and thought blood was going to burst through her head. She felt like her blood pressure was so high) in a 53-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 025c21a and 038c21a) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Type I diabetes mellitus since 09-May-1976, Cholesterol, Hypothyroidism and Drug allergy (codeine). Concomitant products included SIMVASTATIN for Cholesterol, LEVOTHYROXINE for Thyroid atrophy, INSULIN LISPRO (HUMALOG), INSULIN HUMAN, INSULIN HUMAN INJECTION, ISOPHANE (NOVOLIN 10R), INSULIN GLARGINE (LANTUS), MELOXICAM and ACETYLSALICYLIC ACID (ASPIRIN (E.C.)) for an unknown indication.   On 08-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 05-Jun-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 05-Jun-2021, the patient experienced MUSCULOSKELETAL STIFFNESS (very stiff,she felt like she was an 80-85 year old in how she was going down the steps because she was so stiff/body began to feel stiff), FEELING COLD (overwhelmingly cold feeling,shivering visibly/extremely cold), MOBILITY DECREASED (can feel her body like it is not wanting to continue to move,could hardly change from her street clothes to her pajamas/very difficult to get up and move around/could barely move legs to get out of vehicle), MUSCLE DISCOMFORT (her muscles and joints would not work), CHILLS (major chill,shivering/shivering/shaking of limbs from being so cold) and HEADACHE (headache/pulsating and pounding in head/felt like top of head would explode off). On 06-Jun-2021, the patient experienced HYPERTENSION (she could feel blood running through her body, it was pulsating and thought blood was going to burst through her head. She felt like her blood pressure was so high), PAIN IN EXTREMITY (a new pain in her legs that she would get hot spots,her legs would seize in a convulsive pain), FEELING ABNORMAL (felt like she was dying/feel blood rushing through body), MYALGIA (stiffness then turned to pain that moving was excruciating all over even her wrist hurt, her elbow hurt to bend/body sore) and FATIGUE (felt like a truck hit her as she was exhausted/exhausted). On an unknown date, the patient experienced THIRST (she drank four glasses of water that day and four bubbly water cans that were 12 ounces each), PAIN (any movement was painful), MUSCLE SPASMS (muscles in arms and legs began cramping/spasms and cramping), BLOOD GLUCOSE INCREASED (higher than normal blood sugar ranged between 200-300), SLEEP DISORDER (able to sleep 20-30 mins at a time/wake up due to cold/shaking and body pain) and ARTHRALGIA (her muscles and joints would not work). On 07-Jun-2021, MUSCULOSKELETAL STIFFNESS (very stiff,she felt like she was an 80-85 year old in how she was going down the steps because she was so stiff/body began to feel stiff), FEELING COLD (overwhelmingly cold feeling,shivering visibly/extremely cold), MOBILITY DECREASED (can feel her body like it is not wanting to continue to move,could hardly change from her street clothes to her pajamas/very difficult to get up and move around/could barely move legs to get out of vehicle), MUSCLE DISCOMFORT (her muscles and joints would not work), HYPERTENSION (she could feel blood running through her body, it was pulsating and thought blood was going to burst through her head. She felt like her blood pressure was so high), PAIN IN EXTREMITY (a new pain in her legs that she would get hot spots,her legs would seize in a convulsive pain), FEELING ABNORMAL (felt like she was dying/feel blood rushing through body), CHILLS (major chill,shivering/shivering/shaking of limbs from being so cold), HEADACHE (headache/pulsating and pounding in head/felt like top of head would explode off), MYALGIA (stiffness then turned to pain that moving was excruciating all over even her wrist hurt, her elbow hurt to bend/body sore) and FATIGUE (felt like a truck hit her as she was exhausted/exhausted) had resolved. At the time of the report, THIRST (she drank four glasses of water that day and four bubbly water cans that were 12 ounces each), PAIN (any movement was painful), MUSCLE SPASMS (muscles in arms and legs began cramping/spasms and cramping), BLOOD GLUCOSE INCREASED (higher than normal blood sugar ranged between 200-300), SLEEP DISORDER (able to sleep 20-30 mins at a time/wake up due to cold/shaking and body pain) and ARTHRALGIA (her muscles and joints would not work) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No treatment medication was provided by reporter.   Most recent FOLLOW-UP information incorporated above includes: On 19-Jul-2021: Significant follow up received contains patient demographic information, race and ethnic information, non serious events, allergy to codeine, concomitant drug.