woke up extremely swollen/swelling is not just in her face, it's her whole body, arms are all filled up; had bands of lactic acid on her thighs/retaining more water, she is getting bumps on her thigh; gained weight; bumps on her thigh; oxygen doesn't seem to be circulating, so she is having trouble climbing stairs; can hardly walk/difficulty walking; having a lot of pain; This is a spontaneous report from a contactable consumer (patient). A 72-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), on 02Mar2021 (at the age of 72-years-old) as dose 2, single, via an unspecified route of administration for COVID-19 immunisation; botulinum toxin type a (BOTOX, Batch/Lot number was not reported), via an unspecified route of administration from an unspecified date to an unspecified date, at an unspecified dose for an unspecified indication. The patient's medical history was not reported. The patient's concomitant medication included an experimental medication. The patient experienced woke up extremely swollen/swelling is not just in her face, it's her whole body, arms are all filled up, had bands of lactic acid on her thighs/retaining more water, she is getting bumps on her thigh, gained weight, bumps on her thigh, oxygen doesn't seem to be circulating, so she is having trouble climbing stairs, can hardly walk and having a lot of pain on 2021. The clinical course was as follows: The patient got her second dose on 02Mar2021. Seventeen (17) days later, she had a Botox injection. Three (3) days after that, she woke up extremely swollen, and has gained weight. Also had bands of lactic acid on her thighs that she is being treated for that. Asking, has anyone else had this or is there any remedy. The doctor told her there are other people that have reported similar. Also reported water retention from knees up in her legs. Adds that chiropractor said several people have had the same problem. Her dermatologist said 2 weeks ago that 2 people have had issues with water retention after Botox and Covid vaccine. He said one patient had second dose in Jan and it is still going on 7 months later.  He had no idea how long it would last. Mentions that chiropractors use natural medicine, and they didnt know what could be done with that (water retention). They know it is a reaction, and that it looks like she is retaining a lot of water. She was asked by HCP if she got her second dose, and when she started retaining water, then said they have several patients like that. Also asked her internal medicine doctor who gave her same treatment as a hospitalized Covid patients zinc, vitamin C, and lots of vitamins, like Centrum silver with magnesium, also taking B complex aside from that. They told her that her body is reacting the way it would with Covid, like her immune system has overreacted with Botox she was given after injection. Asking whether we have heard of patients with similar situations and how long it will last. Later adds that swelling is not just in her face, it's her whole body, arms are all filled up. States that she is 72, and it doesn't look bad because she has no wrinkles on her body (laughs). Now that she is retaining more water, she is getting bumps on her thigh, even took pictures. Said she has bumps, but unable to determine if she said, thighs, hands, or head. Has never had cellulitis, on her legs up to her knees. Also states that oxygen doesn't seem to be circulating, so she is having trouble climbing stairs. Her thighs and arms were puffed up. She usually weighs herself every day. She had gained weight. That was in March. Now she has gained so much weight. She had to change sizes in her underwear and clothes. She is four foot ten inches and weighing 156 or 157 pounds. She went to different doctors that said they have had other patients that had similar reactions. Her chiropractor had several patients that had water retention after second dose and having that injection for the muscles to not contract and so on in the face. She saw the dermatologist 2 weeks ago and he has two patients with the same thing. She asked the dermatologist when it goes away. He doesn't know when it will go away. He said that one patient got the condition starting in January and it was in July and he still had it. The other patient hasn't returned to the office. How does she get the excess water out of the body? The doctors recommended exercising and she exercises a lot. She does aerobics and hiking. They recommended sleeping more and she does that. They recommended therapy and she tried that. They recommended drinking more than 8 glasses because the body will not keep the water and will release the water. That has not worked. Does the company have any idea of what she can do? Is there a remedy? She saw this doctor that is specialist in beauty treatment and surgeries. She looked at caller's thighs and said it was not fat it was water. She doesn't have fat. She is very muscular. It is not fat, it is water. That is not the whole problem. There is treatment where they treat the lymphatic system. She was sent to a therapist and was told that she had these bands that don't let the water go out. They seem to be bands of lactic acid. She said lactic acid is from protein from meats. She quit eating meats and has very little protein in case that is the problem. This week she checked her again. This is getting worse and now she is getting bumps on her thighs. The water doesn't go beyond her knees. From the knees down to her feet there is no water retention. The water retention is from the knees up. She is getting bumps on her thighs. The bumps are lactic acid, but it has been deposited there. They gave her treatment and the water went out. She can hardly walk due to water retention. She is not getting oxygen or air to her body. She is having difficulty walking and having a lot of pain. After treatment, she was able to walk all weekend and was fine. Last night she noticed one of the legs is getting bumps again. She is really worried if she can't walk and keeps getting the bumps. The treatments are very expensive. The insurance doesn't cover them. The treatments are painful with breaking up the lactic acid bands. She just wanted to know if there are complaints like this before and is there any remedy? As time has gone on, she seems to get more water and more water. Actresses use them to fill up wrinkles. That is not what she used. It is a dangerous bacterium, but it is only a small amount. It makes the muscles in the face and person looks younger. She can't think of what the injection is called. She has gone to extremes to lose the water and not be crippled, and it is not working. The doctors have told her there are other patients with similar circumstances. The doctors said they don't know and that she may have to wait and see if it wears off by itself. The vaccine is supposed to make the immune system react. Apparently, it seems like it is overreacting to this bacterium that is normally used, and nothing happens. She states it is Botox. Botox is the name of the injection. The main doctor treats her. They are treating her for cirrhosis not related to hepatitis and not related to drinking. She is taking an experimental medication and she is the first one in Her Area. She started the experimental medication in Dec2020 and is supposed to end it in Nov2021. She did not get placebo because she is improving. The other patients who had the same experience as she aren't on this treatment, but it may not have anything to do with it. She wanted to bring it up. She visits her ENT weekly. She asked him if he had other patients that had this happen and he said no. Her ENT had prescribed the vitamins and Lipoflavonoide originally. He said she was fine now with her original complaint but to continue drinking them as long as she wanted. In Her Area, people that got COVID19 were given all these vitamins to bring up their immune system. She doesn't know if that would be good or not. She is wondering if after the second dosage of the vaccine her immune system is reacting to the Botox which is a bacterium because the vaccine is supposed to bring up the immune system and react. The dermatologist said she would just have to wait until some time has passed by. She knows her son had problems with the second dose, and he didn't have Botox. She can't continue to gain water. Therapeutic measures were taken as a result of woke up extremely swollen/swelling is not just in her face, it's her whole body, arms are all filled up, had bands of lactic acid on her thighs/retaining more water, she is getting bumps on her thigh, gained weight, bumps on her thigh and can hardly walk. The outcome of the events was unknown.