She got at 8 am on a Sunday. At 5pm that same day, she couldn't move/ She just was unable to get out of bed for 2 days; She just was unable to get out of bed for 2 days.; She wasn't eating; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP), Program ID. The reporter is the patient.  A 70-year-old female patient received BNT162b2 (BNT162B2), on 24Jan2022 as dose number unknown, (booster) single (Lot number: FJ5683) at the age of 69 years for covid-19 immunisation. The patient's relevant medical history included: "High blood pressure" (unspecified if ongoing); "Unreactive thyroid" (unspecified if ongoing); "Hot flashes" (unspecified if ongoing), notes: She had issues with hot flashes and had to go on hormone replacement; "Menopause" (unspecified if ongoing), notes: She had issues with hot flashes early and then when she started menopause they took her off everything and put her on Prempro.; "hormone replacement" (unspecified if ongoing), notes: She was put on a low dosage of birth control because of it which is hormone replacement.; "Sleep disorder" (unspecified if ongoing), notes: She is not able to sleep due to hot flashes. Concomitant medication(s) included: LOSARTAN taken for hypertension; FUROSEMIDE; LEVOTHYROXINE taken for thyroid disorder. Vaccination history included: BNT162b2 (She was fine after her first covid shot, First dose: 31Jan2021-EN5318), administration date: 31Jan2021, when the patient was 68-year-old, for COVID-19 immunization; BNT162b2 (Her second one three weeks later she got at 8 am on a Sunday. At 5pm that same day, she couldn't move., She had to lay down. She was so nauseous. , She was in bed for 3 days., She wasn't eating. She never vomited., Lot: EN6198), administration date: 21Feb2021, when the patient was 68-year-old, for COVID-19 immunization, reaction(s): "She got at 8 am on a Sunday. At 5pm that same day, she couldn't move", "She had to lay down. She was so nauseous", "She was in bed for 3 days", "She wasn't eating". The following information was reported: MOBILITY DECREASED (non-serious), outcome "unknown", described as "She got at 8 am on a Sunday. At 5pm that same day, she couldn't move/ She just was unable to get out of bed for 2 days"; BEDRIDDEN (non-serious), outcome "unknown", described as "She just was unable to get out of bed for 2 days."; DECREASED APPETITE (non-serious), outcome "unknown", described as "She wasn't eating".  Additional information: The patient stated that when she was young, she was on Pfizer's birth control, and she had issues with hot flashes and had to go on hormone replacement. She had issues with hot flashes early and then when she started menopause, they took her off everything and put her on Prempro. She had issues with hot flashes as she got older and then menopause. She was put on a low dosage of birth control because of it which was hormone replacement. She was not able to sleep due to hot flashes. She has always had corporate drug coverage, and they would cover all of her medications 100%. Her husband passed away, so she had to get insurance, and got another plan too. She was fine after her first covid shot. Her second one three weeks later she got at 8 am on a Sunday. At 5 pm that same day, she couldn't move. She had to lay down. She was so nauseous. She was in bed for 3 days. She wasn't eating. She never vomited. She then took a booster dose, and experienced the same thing, but did not have nausea. She just was unable to get out of bed for 2 days. Since the second shot to now, she has had 3 instances where she felt the same way. Like that overwhelming need to lay down. Once it happened when she was outside walking. The second, she was doing laundry and instead of folding laundry right there she threw it in basket and came to her apartment. The 3rd time, she was in her apartment doing something and had to lay down. She gets checked by her doctor twice a year, and nothing was going on. She would just get that same feeling suddenly. And then she was fine. She would now be one month without Prempro because of this. No investigation reported. She still planned to get another booster in Jan2023. She had to talk to her doctor. She never got flu symptoms from the vaccines.