My first period after receiving the 2nd dose, I had debilitating cramps and almost passed out from the pain; My first period after receiving the 2nd dose, I had debilitating cramps and almost passed out from the pain; The flow of blood was much heavier than usual; I have thrown up from the pain; 8 days of vertigo; normal cold sweat; body shakes; extreme fatigue; aching that was expected; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 28-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 06Jun2021 at 12:00 as dose 2, single (Lot number: EW0175) at the age of 28 years, in left arm for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Batch/Lot No: EW0170, Location of injection: Arm Left, Vaccine Administration Time:11:30 AM), administration date: 11May2021, when the patient was 28-year-old, for COVID-19 immunization. The following information was reported: VERTIGO (non-serious) with onset 2021, outcome "not recovered", described as "8 days of vertigo"; PAIN (non-serious) with onset 2021, outcome "not recovered", described as "aching that was expected"; TREMOR (non-serious) with onset 2021, outcome "not recovered", described as "body shakes"; FATIGUE (non-serious) with onset 2021, outcome "not recovered", described as "extreme fatigue"; COLD SWEAT (non-serious) with onset 2021, outcome "not recovered", described as "normal cold sweat"; NAUSEA (non-serious) with onset 23Jun2021 at 13:15, outcome "not recovered", described as "I have thrown up from the pain"; DYSMENORRHOEA (non-serious) with onset 23Jun2021 at 13:15, outcome "not recovered", PRESYNCOPE (non-serious) with onset 23Jun2021 at 13:15, outcome "not recovered" and all described as "My first period after receiving the 2nd dose, I had debilitating cramps and almost passed out from the pain"; HEAVY MENSTRUAL BLEEDING (non-serious) with onset 23Jun2021 at 13:15, outcome "not recovered", described as "The flow of blood was much heavier than usual". The events "my first period after receiving the 2nd dose, i had debilitating cramps and almost passed out from the pain", "the flow of blood was much heavier than usual", "i have thrown up from the pain", "8 days of vertigo", "normal cold sweat", "body shakes", "extreme fatigue" and "aching that was expected" required physician office visit. Therapeutic measures were not taken as a result of dysmenorrhoea, presyncope, heavy menstrual bleeding, nausea, vertigo, cold sweat, tremor, fatigue, pain.  Additional information: The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine or any other medications within 2 weeks of vaccination. Her first period after receiving the 2nd dose, she had debilitating cramps and almost passed out from the pain. The flow of blood was much heavier than usual. Every period since getting the 2nd dose has been this extreme level of cramping (she has thrown up from the pain) and heavy blood flow. For 12 years prior to the vaccine, she would barely have any symptoms during her menstrual cycle. She is 100% sure the change started 2 weeks after getting her 2nd dose. It also triggered about 8 days of vertigo. And the normal cold sweats, body shakes, extreme fatigue, and aching that was expected. She requested to research the effect of COVID-19 vaccine on menstrual cycle, she know that she was not alone.  No follow-up attempts are possible. No further information is expected.