going down her thumb and her fingers are all crinkly; She flunked EKG with an L wave flattening; some redness on her palms and feet; some redness on her palms and feet; they are turning purple-ish; Palms swells up on the outside and is red under her thumb/outer pink area near palms looks all swollen; itch; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 64-year-old female patient received BNT162b2 (BNT162B2), on 17Feb2021 as dose 1, 0.3 ml single (Lot number: EL9266, Expiration Date: 31May2021), in right arm, on 10Mar2021 as dose 2, single (Lot number: EN6205, Expiration Date: 30Jun2021) and on 17Nov2021 as dose 3 (booster), single (Lot number: FF2589) at the age of 64 years for covid-19 immunisation. The patient's relevant medical history included: "Diabetic" (unspecified if ongoing), notes: Diabetic diagnosed years ago; "goiter removed/had a goiter and took out left part of thyroid and left the right part in", start date: 19Oct2019 (unspecified if ongoing); "triglycerides went higher than wanted" (ongoing). Concomitant medication(s) included: METFORMIN oral taken for diabetes mellitus; ROSUVASTIN oral taken for blood triglycerides increased (ongoing); ICOSAPENT ETHYL; LEVOTHYROXINE oral taken for thyroidectomy, start date: 2019. The following information was reported: HAND DEFORMITY (disability), outcome "not recovered", described as "going down her thumb and her fingers are all crinkly"; ELECTROCARDIOGRAM ABNORMAL (medically significant), outcome "not recovered", described as "She flunked EKG with an L wave flattening"; ERYTHEMA (non-serious), PALMAR ERYTHEMA (non-serious), outcome "not recovered" and all described as "some redness on her palms and feet"; SKIN DISCOLOURATION (non-serious), outcome "not recovered", described as "they are turning purple-ish"; PERIPHERAL SWELLING (non-serious), outcome "not recovered", described as "Palms swells up on the outside and is red under her thumb/outer pink area near palms looks all swollen"; PRURITUS (non-serious), outcome "not recovered", described as "itch". The events "palms swells up on the outside and is red under her thumb/outer pink area near palms looks all swollen" and "itch" required physician office visit. The patient underwent the following laboratory tests and procedures: Echocardiogram: but there was nothing there; Electrocardiogram: L wave flattening; had testing: Unknown Result, notes: had testing done and they do not know what it is. Therapeutic measures were taken as a result of erythema, palmar erythema, skin discolouration, peripheral swelling, hand deformity, pruritus.  Additional information: the patient reported that She noticed some redness on her palms and feet, and they are turning purple-ish. 'Has it been reported? Is it permanent or does it go away? She confirmed the previous information. "I hope it goes away. It started and went away for some time, but it came again. It's permanent on my hands and feet now". "I consulted with a rheumatologist, a cardiologist, and a dermatologist, but no one finds anything". She got COVID 19 vaccine and ever since then she has red palms, red feet that sometimes turn purplish color. She has been to all kinds of specialists and had testing done and they do not know what it is. She has been to a cardiologist, endocrinologist, all over the place and they all do not know what it is. Palms swells up on the outside and is red under her thumb. Hard for her since she is left handed and cannot fill out forms because she cannot hold a pen in her hand. She could not figure out what was going on and she went to her Primary. Adverse events started and would go away and then came back and then went away, and then permanently came back and will not go away. She knew adverse events occurred after the COVID vaccine, she did not know when it occurred or after which dose. She had been researching everything, something was wrong here. She did not like when she saw the inner sole part of her foot turn purple. It got worse and then lightened up a little bit, outer pink area near palms looked all swollen. When she pressed on it, looked like her palm was holding water, clarified it turned all white. Underneath her thumbs, going down her thumb and her fingers are all crinkly. She got referrals to go to specialist. She had tried eczema cream or autoimmune creams thinking it is autoimmune. She went to rheumatologist and there is nothing there. She flunked EKG with an L wave flattening, then she did an Echo but there was nothing there. She saw endocrinologist and diabetes specialist; she will go back to diabetes specialist next week to find out results. She is not getting the fourth vaccine. Is it going to be permanent? It's horrible looking and when she puts her shoes on they get tight, it's embarrassing. It will itch once in a while but other than that it is just there. There was no Prior Vaccinations (within 4 weeks) within four weeks prior to the first administration date of the suspect vaccine. AE(s) following prior vaccinations: not that she is aware of, she just had shingles shot that she was 10 years late on, got shingles shot on Monday.