flare-ups where my eyes get completely puffy; underneath my eyes there's splotches of red patches; flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks; Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 48-year-old female patient received BNT162b2 (BNT162B2), as dose 4 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "I am allergic to Penicillin" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, Lot Number unknown), when the patient was 48 years old, for Covid-19 immunization, reaction(s): "Flare-ups where my eyes get completely puffy"; Bnt162b2 (DOSE 1, SINGLE,  Lot Number unknown), when the patient was 48 years old, for Covid-19 immunization, reaction(s): "Underneath my eyes there's splotches of red patches", "Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks"; Bnt162b2 (DOSE 2, SINGLE,  Lot Number unknown), when the patient was 48 years old, for Covid-19 immunization, reaction(s): "Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks", "Underneath my eyes there's splotches of red patches", "Flare-ups where my eyes get completely puffy", "Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks"; Bnt162b2 (DOSE 3 (BOOSTER), SINGLE,  Lot Number unknown), when the patient was 48 years old, for Covid-19 immunization, reaction(s): "Underneath my eyes there's splotches of red patches", "Flare-ups where my eyes get completely puffy", "Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks". The following information was reported: PERIORBITAL SWELLING (non-serious), outcome "unknown", described as "flare-ups where my eyes get completely puffy"; OCULAR HYPERAEMIA (non-serious), outcome "unknown", described as "underneath my eyes there's splotches of red patches"; SWELLING FACE (non-serious), outcome "unknown", described as "flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks"; EYE SWELLING (non-serious), outcome "unknown", described as "Flare up where my entire face just completely swelled up specifically my eyes and underneath my cheeks". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: It was reported that the patient last Pfizer shot in Dec2021, and the past couple of months had been just getting those off-and-on what she thought were allergic reactions. But they were stupid flare-ups where her eyes got completely puffy, and even underneath her eyes there was splotches of red patches, so seemingly looked like an allergic reactions. She worked on the computer all day, so not being able to see because of these puffy eyes was not good. It was reported that she received all three Pfizer vaccines (Confirmed as Covid 19 vaccine), the two of the boosters the last time she got the shot was December for the past couple of the months she had experienced just somewhat flare up where her entire face just completely swelled up specifically her eyes and underneath her cheeks. She got allergy tested, was literally not allergic to anything. She had a Rheumatologist check out for lupus, that was not the answer. She was allergic to Penicillin.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.