Vaccines exacerbated her Fatigue syndrome/Vaccines caused her to relapse/Patient was exhausted; Vaccines exacerbated her Fibromyalgia/Vaccines caused her to relapse/Muscle pain; Stomach was upset for weeks; Eyes were blurry; Patient was immobilized/Patient couldn't do anything; This spontaneous case was reported by a consumer and describes the occurrence of IMMOBILE (Patient was immobilized/Patient couldn't do anything) in a 77-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Shellfish allergy, Drug allergy (Sensitive to medication), Chronic fatigue syndrome (Fatigue syndrome) and Fibromyalgia.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced IMMOBILE (Patient was immobilized/Patient couldn't do anything) (seriousness criterion medically significant), CHRONIC FATIGUE SYNDROME (Vaccines exacerbated her Fatigue syndrome/Vaccines caused her to relapse/Patient was exhausted), FIBROMYALGIA (Vaccines exacerbated her Fibromyalgia/Vaccines caused her to relapse/Muscle pain), ABDOMINAL DISCOMFORT (Stomach was upset for weeks) and VISION BLURRED (Eyes were blurry). At the time of the report, IMMOBILE (Patient was immobilized/Patient couldn't do anything), ABDOMINAL DISCOMFORT (Stomach was upset for weeks) and VISION BLURRED (Eyes were blurry) had resolved and CHRONIC FATIGUE SYNDROME (Vaccines exacerbated her Fatigue syndrome/Vaccines caused her to relapse/Patient was exhausted) and FIBROMYALGIA (Vaccines exacerbated her Fibromyalgia/Vaccines caused her to relapse/Muscle pain) outcome was unknown.            Patient was asking if the 2nd booster is half dose, she mentioned she had side effects from the full doses of the moderna COVID-19 vaccines that lasted 3 months and that with the 1st booster (half dose) the side effects only lasted 3 weeks.  Patient had Fatigue syndrome and fibromyalgia before the vaccines, but the vaccines exacerbated the conditions, caused her to relapse.  No concomitant medications reported. No treatment details provided.  Company Comment :This spontaneous case concerns a 77-year-old female patient with medical history of Chronic fatigue syndrome and Fibromyalgia, which experienced the serious (due to medically significant), unexpected event of immobile and other non-serious events, which occurred on an unknown date after the 2nd dose of the mRNA-1273 vaccine. She reported that the vaccines exacerbated the fatigue syndrome and fibromyalgia she had. She was immobilized, had muscle pain, stomach was upset for weeks, her eyes were blurry, she was exhausted. The symptoms lasted for 3 months. The mentioned medical history remains a confounder for the events of immobile, chronic fatigue syndrome, fibromyalgia. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-528393.   Most recent FOLLOW-UP information incorporated above includes: On 30-Mar-2022: Snapshot appended and included no new information.; Sender's Comments: This spontaneous case concerns a 77-year-old female patient with medical history of Chronic fatigue syndrome and Fibromyalgia, which experienced the serious (due to medically significant), unexpected event of immobile and other non-serious events, which occurred on an unknown date after the 2nd dose of the mRNA-1273 vaccine. She reported that the vaccines exacerbated the fatigue syndrome and fibromyalgia she had. She was immobilized, had muscle pain, stomach was upset for weeks, her eyes were blurry, she was exhausted. The symptoms lasted for 3 months. The mentioned medical history remains a confounder for the events of immobile, chronic fatigue syndrome, fibromyalgia. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.