most intense beating of Grover's / It's really really bad case of Grover's disease/Scratching to point where I am bleeding; Can't sleep and relax; Grover's condition aggravated; This spontaneous case was reported by a consumer and describes the occurrence of TRANSIENT ACANTHOLYTIC DERMATOSIS (most intense beating of Grover's / It's really really bad case of Grover's disease/Scratching to point where I am bleeding), INSOMNIA (Can't sleep and relax) and CONDITION AGGRAVATED (Grover's condition aggravated) in a 70-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 048L21A) for COVID-19 vaccination.     The patient's past medical history included Tinnitus (drug induced), Pneumonia (he was overdosed with antibiotics and had Pneumonia 5 times in last 10 years), Drug overdose (Antibiotics), Drug overdose (Pharmaceutical product) and Prostate surgery. Concurrent medical conditions included Gout, Blood pressure high, Immunocompromised and Grover's disease. Concomitant products included LOSARTAN and AMLODIPINE for Blood pressure high, FEBUXOSTAT (ULORIC) for Gout, MORNIFLUMATE (FLOMAX [MORNIFLUMATE]) for Prostate surgery.    On 12-Apr-2022, the patient received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced TRANSIENT ACANTHOLYTIC DERMATOSIS (most intense beating of Grover's / It's really really bad case of Grover's disease/Scratching to point where I am bleeding), INSOMNIA (Can't sleep and relax) and CONDITION AGGRAVATED (Grover's condition aggravated). At the time of the report, TRANSIENT ACANTHOLYTIC DERMATOSIS (most intense beating of Grover's / It's really really bad case of Grover's disease/Scratching to point where I am bleeding), INSOMNIA (Can't sleep and relax) and CONDITION AGGRAVATED (Grover's condition aggravated) outcome was unknown.            Patient was diagnosed with Grover's diseases few years ago. And also after the booster shot, for 5-6 days he has had the most intense beating of Grover's. Symptoms were mentioned as whole body was itching and hurting. All over the body, head, armpit, chest, arms, crotch, hands, legs, and feet.  No treatment medications reported.  Company Comment: This spontaneous case concerns a 70-year-old male immunocompromised patient, with relevant medical history of Grover's disease, who experienced the unexpected events of Transient acantholytic dermatosis, Condition aggravated and Insomnia. The events occurred on an unknown date after receiving the fourth dose of mRNA-1273 Vaccine. Symptoms were mentioned as whole body was itching and hurting. No treatment medications reported. The outcome of the events was reported as unknown. The patient's medical history of being immunocompromised and having Grover's disease, remain as confounders for the occurrence of the events. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   This case was linked to MOD-2022-550528 (Patient Link).; Sender's Comments: This spontaneous case concerns a 70-year-old male immunocompromised patient, with relevant medical history of Grover's disease, who experienced the unexpected events of Transient acantholytic dermatosis, Condition aggravated and Insomnia. The events occurred on an unknown date after receiving the fourth dose of mRNA-1273 Vaccine. Symptoms were mentioned as whole body was itching and hurting. No treatment medications reported. The outcome of the events was reported as unknown. The patient's medical history of being immunocompromised and having Grover's disease, remain as confounders for the occurrence of the events. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.