Extreme shortness of breath; His immune system had a bad reaction to the vaccine; hypoxemic respiratory failure; Pulmonary vasculitis; He had some blood clots; Inflammation and damage to his blood vessels in his lungs was due to cytokine that were out of control and just fill his lungs with blood cells; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP).  A 76 year-old male patient received bnt162b2 (BNT162B2), administration date 24Oct2021 (Lot number: 320308) at the age of 76 years as dose 2, single for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose 1), administration date: Oct2021, when the patient was 76 years old, for COVID-19 Immunization. The following information was reported: RESPIRATORY FAILURE (death, medically significant) with onset 2021, outcome "fatal", described as "hypoxemic respiratory failure"; PULMONARY VASCULITIS (death, medically significant) with onset 2021, outcome "fatal", described as "Pulmonary vasculitis"; THROMBOSIS (medically significant) with onset 2021, outcome "unknown", described as "He had some blood clots"; CYTOKINE STORM (medically significant) with onset 2021, outcome "unknown", described as "Inflammation and damage to his blood vessels in his lungs was due to cytokine that were out of control and just fill his lungs with blood cells"; DYSPNOEA (non-serious) with onset Nov2021, outcome "unknown", described as "Extreme shortness of breath"; IMMUNE SYSTEM DISORDER (non-serious) with onset 2021, outcome "unknown", described as "His immune system had a bad reaction to the vaccine". The event "extreme shortness of breath" was evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: investigation: (22Dec2021) unknown result. The patient date of death was 28Dec2021. The reported cause of death was respiratory failure, pulmonary vasculitis. It was not reported if an autopsy was performed. Clinical Course: Well reporter just wanted to report what she believed was a potential side effect from the vaccine, her husband received his second dose of the vaccine in 24Oct2021, About a week and a half after that he started experiencing extreme shortness of breath we went to the doctor he died on 28Dec2021 of this year and the cause of death was listed as hypoxemic respiratory failure and pulmonary Vasculitis and she believed that his immune system had a bad reaction to the vaccine and the inflammation and  damage to his blood vessels in his lungs was due to cytokine that were out of control and just fill his lungs with blood cells and he had some blood clots so I just wanted to report that." Treatment : Reporter stated, "Well he went to the hospital (further details of hospitalization were unknown) and they were trying to figure out what was going on but nobody ever did they came up with an immune response at one point." Prior vaccination before four week : Reporter stated, "Well he got the first shot and then three week later he got the second shot." When probe when the patient went to hospital: Reporter stated, "He went twice, went early in December and then they were, they were going to do a test and he went in 22Dec2021 for that test so that, he passed away on 28Dec2021 (further details of hospitalization were unknown)." When probe if anything else to help with : Reporter stated, "No that is it she just wanted to make sure somebody knew about it."  No follow-up attempts are possible. No further information is expected.; Reported Cause(s) of Death: hypoxemic respiratory failure; pulmonary vasculitis