Knee joint pain,shoulder joint pain/ arm joint pain/ got all joint pain/shoulder joint pain; Reactive arthritis; Condition progressively got worse; numbness of his hands/ his sleep hands; pinched nerve; Herniated disc; Shoulders froze up; his hand is twice the size; Fingers could not bend; all joints are swollen (arms, elbows, knees, shoulder), he is all swollen up; I could barely move; Could not lift arm; usual side effects of injections; muscle pain; Fingers tingling; This spontaneous case was reported by a consumer and describes the occurrence of ARTHRALGIA (Knee joint pain,shoulder joint pain/ arm joint pain/ got all joint pain/shoulder joint pain) and ARTHRITIS REACTIVE (Reactive arthritis) in a 60-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 0021B21A and 010A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history provided by the reporter.    On 12-Mar-2021 at 2:30 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 13-Apr-2021 at 1:50 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 01-May-2021, the patient experienced ARTHRALGIA (Knee joint pain,shoulder joint pain/ arm joint pain/ got all joint pain/shoulder joint pain) (seriousness criterion hospitalization) and PARAESTHESIA (Fingers tingling). On an unknown date, the patient experienced ARTHRITIS REACTIVE (Reactive arthritis) (seriousness criterion medically significant), CONDITION AGGRAVATED (Condition progressively got worse), HYPOAESTHESIA (numbness of his hands/ his sleep hands), NERVE COMPRESSION (pinched nerve), INTERVERTEBRAL DISC PROTRUSION (Herniated disc), PERIARTHRITIS (Shoulders froze up), PERIPHERAL SWELLING (his hand is twice the size), MUSCULOSKELETAL STIFFNESS (Fingers could not bend), JOINT SWELLING (all joints are swollen (arms, elbows, knees, shoulder), he is all swollen up), HYPOKINESIA (I could barely move), LIMB DISCOMFORT (Could not lift arm), INJECTION RELATED REACTION (usual side effects of injections) and MYALGIA (muscle pain). The patient was hospitalized from 03-Jul-2021 to 03-Jul-2021 due to ARTHRALGIA. The patient was treated with GABAPENTIN for Numbness in hand, at an unspecified dose and frequency. At the time of the report, ARTHRALGIA (Knee joint pain,shoulder joint pain/ arm joint pain/ got all joint pain/shoulder joint pain), CONDITION AGGRAVATED (Condition progressively got worse), HYPOAESTHESIA (numbness of his hands/ his sleep hands), INTERVERTEBRAL DISC PROTRUSION (Herniated disc), PERIARTHRITIS (Shoulders froze up), PERIPHERAL SWELLING (his hand is twice the size), JOINT SWELLING (all joints are swollen (arms, elbows, knees, shoulder), he is all swollen up), HYPOKINESIA (I could barely move), PARAESTHESIA (Fingers tingling), LIMB DISCOMFORT (Could not lift arm) and MYALGIA (muscle pain) had not resolved and ARTHRITIS REACTIVE (Reactive arthritis), NERVE COMPRESSION (pinched nerve), MUSCULOSKELETAL STIFFNESS (Fingers could not bend) and INJECTION RELATED REACTION (usual side effects of injections) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Blood test: normal (normal) Normal Blood Tests. In 2021, Inflammatory marker test: increased (High) increased Inflammatory marker. In 2021, Weight: lost 40 pounds (Low) lost 40 pounds of body and muscle mass.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Many doctor's were consulted. The details of visits were not specified. On 22-06-2021: X-ray  with unknown result. On 25-06-2021: CT Scan with unknown result. On 30-06-2021: MRI. The patient did not take any concomitant medications. In first week of May the patient started feeling achy, joint pain, shoulder pain, swelling thigh knee and hip painful. Each of progressively got worse. Hands continued to be numb and finger tingling not able to bend. Knee swollen and not able to bend  and pain most of the time on right side than moved to left side and than both side.  No concomitant medication was reported. 11 Aug 2021 EMG test was done with unknown result   Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.   Most recent FOLLOW-UP information incorporated above includes: On 04-Aug-2021: Upon follow-up receipt : Event details (Nerve compression, Intervertebral disc protrusion, Periarthritis, Musculoskeletal stiffness, Hypokinesia, Paraesthesia), Hospitalization details, case seriousness was updated.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.