lost power on arms and legs and ended up in hospital; he went to pick something up, couldn't get up off floor; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A male patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), in Sep2022 as dose 5 (booster), single (Batch/Lot number: unknown) for covid-19 immunization. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (In Mar2021, got the Pfizer CN6206., DOSE 1, SINGLE), administration date: Mar2021, for COVID-19 Immunization, reaction(s): "no problem"; Bnt162b2 (A couple of weeks later, got the second vaccine and had no problems what so ever, no reactions, DOSE 2, SINGLE), administration date: Mar2021, for COVID-19 Immunization, reaction(s): "no problem"; Bnt162b2 (DOSE 3 (BOOSTER), SINGLE), administration date: Sep2021, for COVID-19 Immunization, reaction(s): "lost power on arms and legs and ended up"; Bnt162b2 (DOSE 4 (BOOSTER), SINGLE), administration date: Apr2022, for COVID-19 Immunization, reaction(s): "lost power on arms and legs and ended up". The following information was reported: MONOPLEGIA (hospitalization, medically significant), outcome "unknown", described as "lost power on arms and legs and ended up in hospital"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (hospitalization), outcome "unknown", described as "he went to pick something up, couldn't get up off floor".  Clinical course: The patient mentioned he received the first two COVID-19 Vaccine doses on Mar2021and was everything was fine, he had no problem. Then, on Sep2021 he received the booster and 24 hours later he lost power on arms and legs and wound up on the floor ended up in hospital after 911 call and then he had to take some therapy. On Apr2022, he got another booster and again got the same reaction 24 hours later. On Sep2022, he took another booster and the same thing happened. Does not have exact dates but, Sep2022 this year, had another booster and had the same reaction, lost all power in arms and legs and went on the floor. Couldn't get up and had to call (withheld) and wound up in the hospital and then wound up in rehab. Was the same thing that happened the first time. Here's the thing, obviously, there was no way he was going to get another booster. Got the booster shot and was fine. 24 hours later, when he went to pick something up, couldn't get up off floor and lost all power in arms and legs. Another couple of times, went to hospital and ended up in rehab. When he went to hospital, was kept there several days and then put in rehab to get stronger. The patient referred to his HCP, he mentioned that in one of the visits, he was told the booster reacts with immunological system and that his doctor said things that didn't made sense, and that he was actually medical misdiagnosed, which is common to happen to him.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201325029 same reporter/patient/event, different drug dose;