Inflammation; Tingly just went to the palm of his hand but still had the tingling feeling; Nose, cheeks and face were swollen and left side of his nose has a raised bump on it; Feeling spread to his heart and chest and it just felt like he was scared; Left arm was hurting like he hit his funny bone all the way down to finger tips like electricity; Initial information regarding an unsolicited valid non-serious case was received from a pharmacist via consumer/non-health care professional via Medical Information (Reference number- 00786224) and transmitted to Sanofi on 27-Sep-2021.  This case involves an 84-year-old male patient who had left arm was hurting like he hit his funny bone all the way down to finger tips like electricity (pain in extremity), inflammation, feeling spread to his heart and chest and it just felt like he was scared (feeling abnormal), nose, cheeks and face were swollen and left side of his nose has a raised bump on it (swelling face) and tingly just went to the palm of his hand but still had the tingling feeling (paraesthesia) after receiving INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE [FLUZONE HIGH-DOSE QUADRIVALENT].  Medical history, medical treatment(s), vaccination(s), concomitant medication(s) and family history were not provided.   On 09-Sep-2021, the patient received a 0.7 ml dose of suspect INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE (batch number and expiry not reported) via unknown route in unknown administration site for prophylactic vaccination.  On 09-Sep-2021 (at: 8pm) the patient developed a non-serious left arm was hurting like he hit his funny bone all the way down to fingertips like electricity (pain in extremity) on the same day following the administration of INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE.  On 20-Sep-2021 the patient developed a non-serious feeling spread to his heart and chest and it just felt like he was scared (feeling abnormal) 11 days following the administration of INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE.  On 26-Sep-2021 the patient developed a non-serious nose, cheeks and face were swollen and left side of his nose has a raised bump on it (swelling face) 17 days following the administration of INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE.  On an unknown date the patient developed non-serious inflammation and tingly just went to the palm of his hand but still had the tingling feeling (paraesthesia) (unknown latency) following the administration of INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE.  It was reported "Caller stated that he got our vaccine FLUZONE high dose (HD) quadrivalent (QUAD) on 09Sep2021 and he has a terrible reaction to it. Caller would like to know what should he do to get better? Caller stated on 9/9/2021 he got the FLUZONE HD Quad vaccine around 12p-1p in his left arm. Caller stated that around 8pm that same day his left arm was hurting like he hit his funny bone all the way down to fingertips like electricity. On 9/12 he called doctor and they told him to come in and he put him on 2mg on Prednisone (Rayos) a delayed release tablet for inflammation. Then the next morning it moved to chest then face and to his heart then on 9/17 he was told to call the centers for disease control and prevention (CDC) and they to him to call vaccine adverse event reporting system (VAERS) on 9/18 and they called him on 9/20 and they took his statement and gave him a report number: 650473. They told him to keep his Doctor informed and that night the feeling spread to his heart and chest and it just felt like he was scared. That morning of 9/21 Emergency Room. They did a chest X-ray, Computed tomography (CAT) Scan of brain, and Cardiogram and blood work. All were negative. They told him to go home let it play out and take nothing. 9/23-9/24 they were slightly better conditions but the tingly just went to the palm of his hand but still had the tingling feeling but not as bad. Then on 9/25 went to consumer value store and got Manufacture information about the vaccine because he just does not know what to do to get better. Then on 9/26 his nose, cheeks and face are swollen and left side of his nose he has a raised bump on it, and this morning he took a Claritin D for the swelling."  Relevant laboratory test results included: On 21-Sep-2021,  Blood test (Negative),  Chest X-ray (Negative), Computerised tomogram head (Negative) and  Electrocardiogram (Negative).  The patient was treated with PREDNISONE (RAYOS) (2 mg) for Inflammation and LORATADINE, PSEUDOEPHEDRINE SULFATE (CLARITIN-D) for Swelling face.   It was not reported if the patient received any corrective treatment for other events.  At time of reporting, the event paraesthesia was not recovered while outcome of other events was unknown.  There will be no information available on the batch number for this case.