her crows feet has returned/ her forehead creases are back; Botox has completely diminished; Botox has completely diminished; This is a spontaneous report from a contactable consumer, the patient. This consumer reported via telephonic response.  A 45-year-old non-pregnant female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 m-RNA VACCINE, formulation: solution for injection, lot number was not reported, age at vaccination: 45-year-old), dose 2 via an unspecified route of administration on 30Apr2021 as dose 2, single for covid-19 immunisation, botulinum toxin type a (BOTOX), via an unspecified route of administration on 15Mar2021 (Batch/Lot number was not reported) and ongoing, at 50 units total (30 units in the forehead and 10 units in each eye) for fine lines in forehead and crows feet. Medical history included ongoing hypothyroidism. Concomitant medication included levothyroxine sodium (SYNTHROID) for hypothyroidism and start and stop date were not reported (she had been taking it for 6 years with Botox). The patient previously received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 m-RNA VACCINE, formulation: solution for injection lot number was not reported), via an unspecified route of administration on an unknown date as dose 1, single for covid-19 immunisation and botox on an unknown date for unknown indication and experienced no adverse event. The patient was not pregnant at the time of vaccination and was not nursing/breastfeeding. On an unknown date in May2021, the patient's crows feet has returned/ her forehead creases are back and botox has completely diminished. The patient reported that she received her botox on 15Mar2021 and then got her second Pfizer shot on 30Apr2021 and her Botox has completely diminished. The patient did not have the lot no and expiration date for the Botox Cosmetic. The patient stated she noticed in the last few days her forehead creases were back and her crows feet has returned. The patient stated these events started a week after she got her second Pfizer Covid vaccine. The patient stated when she got Botox Cosmetic it usually lasted for 5 months. The patient stated she had used Botox Cosmetic in the past with no adverse events and she stated she did not get any adverse events from the vaccine. The patient stated she did not want to go back and get another Botox Cosmetic injection based on the timing (her last injection was 15Mar2021) and but she did want to plan in case they give her a booster. She wanted to know if this was what other people were talking so the patient was transferred to an agent at Medical Information to answer her inquiry on Botox and the Pfizer Covid vaccine. The patient provided her HCP's information and granted permission to follow up with the HCP. Have never had issues with Botox. The patient's relevant laboratory tests were none. The patient was not hospitalized or was hospitalization prolonged as a result of the AE. The severity of events were unknown or not reported. The outcome of the event was not recovered. The action taken in response to the events for botulinum toxin type a was Unknown.  No follow-up attempts are needed; information about lot/batch number cannot be obtained.