weakness in both arms and legs; fatigue; brain fog; memory challenges; The palm of his hand went completely numb; The ulna and medial nerves are inflamed; both hands they were inflamed; pins and needles in both arms and legs; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 58-year-old male patient received BNT162b2 (BNT162B2), on 22Nov2021 as dose 3 (booster), single (Batch/Lot number: unknown) at the age of 58 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "knee surgery" (unspecified if ongoing), notes: Patient(s) Medical History: knee surgery in 2018; "Meniere symptoms" (unspecified if ongoing), notes: Meniere symptoms in right ear and thought he had fluid build up. The patient's family history included: "Heart issue in family" (unspecified if ongoing), notes: Heart issue in family with his dad and brother. Concomitant medication(s) included: METOPROLOL [METOPROLOL SUCCINATE]; TRIAMTREN HYDROCHLOROTHIAZIDE taken for meniere's disease, stop date: Jun2022; OMEPRAZOLE; FAMOTIDINE, stop date: May2022; ZETIA. Vaccination history included: BNT162b2 (Dose 1, Single, LOT: EM9809, Anatomical Location: Arm), administration date: 08Mar2021, when the patient was 57-year-old, for COVID-19 immunization; Bnt162b2 (Dose 2, Single, LOT: EN6207, Anatomical Location: Arm), for COVID-19 immunization, reaction(s): "bursitis", "red knee", "infection", "right knee swelled up so bad"; Flu vaccine (Prior Vaccinations (within 4 weeks) If applicable: Back in October before he got the third shot he had his regular flu shot. He is not sure if it was 4 weeks, it might have been longer, but it was close., Vaccine Name: Flu Shot, Manufacturer: unknown, LOT: unknown, Date: he doesn't have specific date. , He could go to the pharmacy where he was given the flu shot. He hasn't researched that one), administration date: Oct2021, for immunization. The following information was reported: PARAESTHESIA (non-serious) with onset Nov2021, outcome "recovered" (Feb2022), described as "pins and needles in both arms and legs"; ASTHENIA (non-serious), outcome "unknown", described as "weakness in both arms and legs"; FATIGUE (non-serious), outcome "unknown"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "brain fog"; MEMORY IMPAIRMENT (non-serious), outcome "unknown", described as "memory challenges"; HYPOAESTHESIA (non-serious), outcome "unknown", described as "The palm of his hand went completely numb"; NEURITIS (non-serious), outcome "unknown", described as "The ulna and medial nerves are inflamed"; INFLAMMATION (non-serious), outcome "unknown", described as "both hands they were inflamed". The events "pins and needles in both arms and legs", "weakness in both arms and legs", "fatigue", "brain fog", "memory challenges", "the palm of his hand went completely numb", "the ulna and medial nerves are inflamed" and "both hands they were inflamed" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of paraesthesia, asthenia, fatigue, feeling abnormal, memory impairment, hypoaesthesia, neuritis, inflammation.  Additional Information: This has been going on since Nov2021 when he got third shot. Within a week or two of getting the third shot he got pins and needles in both arms and both legs. He has been trying to rule out everything else. He has seen so many doctor and cant figure out what is going on. It is still going on and driving him crazy. The pins and needles lasted into Feb and that has subsided. It has been so long that it is starting to blend together. Started to develop weakness in arms and legs that is bilateral. It is both arms and both legs. He is fatigued. He has seen cardiologist. He has always seen cardio. He had stress test.fine from cardiologist standpoint. He has seen neurologist. Did nerve conduction study and detected some oddness, but doesnt think he has MS or ALS. They were worried about the worst things and ruled that out. He has seen primary care. He is going to have upper and lower GI next week. They just dont know. The only thing he has is a date correlation. It was days between this starting and the third shot. This probably doesnt have anything to do with the vaccine. Caller doesnt want anyone else to experience this. It has been bad. For the pins and needles go to see chiropractor.The palm of his hand went completely numb.That kind of came on after the pins and needles. It has progressed to different things. When it was feeling weird he thought he might be putting too much alcohol sanitizer on his hands because that feels weird. Then he realized his hands were numb when he crushed the cups. The neurologist said 3 months later that he might have carpal tunnel. The medial is the thumb and bigger fingers. On both hands they were inflamed. That came on after pins and needles.Caller states he is currently dealing with the weakness in bilateral arms and legs and the fatigue. he was on several medications. The patient was Metoprolol probably started it 5 years ago. He stopped it as part of this regiment and the fatigue. The cardiologist said to stop Metoprolol thinking it might be the cause. He has been off since May or Jun2022. The patient also had triamtren hydrochlorothiazide for Meniere symptoms in right ear and thought he had fluid build up. That was back in the 90s and was prescribed by ENT. It was taken off of this medication during this process to see if it was a drug causing this.He had been on it 25 plus years when he stopped taking it. He stopped taking in later part of Jun2022.The cardiologist probably had him on Crestor at that time for cholesterol.They took him off and put him on Zetia. Caller stopped Zetia a week ago and they are going to put him on something else.There were two other prescriptions he was on at the time. He was on the prescription version of Pepcid and Prilosec. Caller clarified Prilosec as Omeprazole and Pepcid as Famotidine.The person he is seeing for upper GI said to stop Pepcid version, Famotidine, so he stopped that in May2022 timeframe. He should still be taking Prilosec version, Omeprazole, but stopped taking it 1 to 2 weeks ago. He took it in the morning and around 10AM he would get severe weakness. he has had blood work all the time. They draw blood from him. The only thing they detected one time was his B12 which if it gets low can cause pens and needles. He wasnt out of the range. If the range was 200-1200, his B12 would be at 325. He wasnt below. He had pins and needles, numbness, and for a period of time he had brain fog. He felt like he couldnt find the right word. His concentration was not where it should have been. That was another neurological challenge. That seems to be less now as well.It was brain fog and memory challenge. That has gotten has less.   The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.