wake up in the middle of the right with the pens and needles tingling sensation; becoming tired as the day progressed; herpes presented as cold; patchy with numbness in right hip & thigh; herpes on her right buttock; sensation of pens and needles tingling at the injection site; pens and needles tingling that eventually started to pass into entire right arm, and then moved to right leg; Initial information regarding an unsolicited valid non-serious was received from a Consumer/non-hcp (healthcare professional) via Medical Information (Refnerence number- 00495438).  This case involves a 61 years old female patient who experienced pens and needles tingling that eventually started to pass into entire right arm, and then moved to right leg (paraesthesia), wake up in the middle of the right with the pens and needles tingling sensation (middle insomnia), herpes presented as cold (nasopharyngitis), patchy with numbness in right hip & thigh (hypoaesthesia), herpes on her right buttock (herpes virus infection), becoming tired as the day progressed (fatigue) and sensation of pens and needles tingling at the injection site (vaccination site paraesthesia), while she received vaccine INFLUENZA QUADRIVALENT RECOMBINANT VACCINE [FLUBLOK QIV].  Medical history, past medical treatments, past vaccinations, concomitant medication and family history were not provided.  On 29-Jan-2021, the patient received a first dose of suspect INFLUENZA QUADRIVALENT RECOMBINANT VACCINE (lot number and expiration date were not reported) via unknown route in right arm for prophylactic vaccination.  On 29-Jan-2021, on same day patient started to experience the sensation of pens and needles tingling at the injection site (vaccination site paraesthesia). As the day progressed and throughout the rest of that day, she continued to have the pens and needles tingling that eventually started to pass into her entire right arm (paraesthesia). After about 2 weeks of these symptoms, the pens and needles tingling continued in her right arm and then moved to her right leg (paraesthesia). The right arm and leg symptoms continued, then. after a few hours, the sensation would go away and return, this continued from around 13-Feb-2021 into the following week. The sensation would return during the night as she would wake up in the middle of the right with the pens and needles tingling sensation (middle insomnia). She was able to get back to sleep, and when she would wake up for the next few days, the sensation would come & go, following the administration of vaccine.   On 18-Feb-2021, after 20 days patient experienced herpes on her right buttock (herpes virus infection), the herpes presented as cold (nasopharyngitis) and patchy with numbness in her right hip & thigh (hypoaesthesia). This continued through 21-Feb-2021, still with the on & off pens and needles tingling presence but was then running from her right hip to her toe and has continued since, following the administration of vaccine.  Patient continued with her normal days exercising with no real discomfort except for the off and on pens and needles tingling and was becoming tired as the day progressed (fatigue) on an unknown date after vaccination.  It was reported that the vaccine the vaccine was quick & painless. Patient never felt weakness or imbalance. Physician suggested that she has an MRI of her brain and did not think that these symptoms have come from taking the Flublok. she plans to see a local neurologist for a consult & MRI (Magnetic resonance imaging).  Relevant laboratory test results included: Patient's blood pressure and reflexes were good.  It was not reported if the patient received any corrective treatment or not.  The patient was recovered from all the events.  There will be no information on the batch number for this case.