Has been having anxiety and palpitations; Has been having anxiety and palpitations; One arm was having tingling and numbing to the feet, arms and hands; One arm was having tingling and numbing to the feet, arms and hands; one arm was having tingling and numbing to the feet, arms and hands/Got worse and worse after the second shot; vitamin D was low; This is a spontaneous report received from a contactable consumer (patient). A 67-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Right on 18Mar2021 (Lot Number: EN6204) as 0.3 mL, single for Covid-19 immunisation. Vaccination facility type was Hospital. Prior vaccinations within 4 weeks was No. Patient took the first dose in Arm Left on 25Feb2021 (Lot Number: EN6200) for Covid-19 immunization. A couple of hours after the first dose, had a rash and hives on one side of the face, the same side of the body as the shot. Went away the next day. Between the first and second dose, like a week after, one arm was having tingling and numbing to the feet, arms and hands. Rash and bumpy hives in left side of face and to neck, which was in same side of body as shot which was in the left arm. Started 6 hours after the first shot. Was a bumpy rash but no itching. Looked at her face and could feel the bumps. Went away the next day and really subsided. Could feel a little bit but not bumpy. Lasted a few hours over night. Treatment included put some Benadryl cream on it. Medical history included chronic back pain, said they had questioned structural heart disease but that it was only high heart rate. Concomitant medications included metoprolol (METOPROLOL XL SANDOZ) taken for blood pressure abnormal from an unspecified start date and ongoing; estradiol taken for hormone therapy from an unspecified start date and ongoing, and took routine daily medications. Between the first and second dose, one arm was having tingling and numbing to the feet, arms and hands. Got worse and worse after the second shot. Went to primary doctor 2 times, who said that it was her immune system reacting to the Covid vaccine. It has been almost four weeks, will be four weeks this Thursday after the second shot. Is getting worried. Read up something saying that people may have multisystem inflammatory system response. Read this in the Covid-19 information from Pfizer. Confirmed that caller is referring to the Covid-19 vaccine. As she is talking now, her left arm and feet are tingling. Has doctor appointment tomorrow to rule out anything in the spine. Has a history of back pain. Back pain never causes tingling like this, only pain and is not usually in her arm. Even talking now, forearm is tingling and the feet. As a nurse, she is thinking it could be all kinds of diseases. She thought to herself does she have MS or ALS, but the Doctor tested everything and all tests were negative, there is nothing that supports any sort of muscular problem. Decided to call Pfizer to see if anyone else has tingling. Wants to let people know that this might happen. All of this happened after the vaccine. Saw primary doctor 09Apr2021, has another appointment tomorrow behind her back. Has to rule everything out, so she may need an MRI. Has chronic back pain, it hurts, but usually no tingling. This has gone on many years with no tingling. It is in her hand and forearm. Read today for the first time that it may be multisystem inflammatory syndrome. Has been seen in the office two times for the numbing and tingling. They tested her for Lupus and everything was normal. Just her vitamin D was low. Patient did not have rash after second dose of the vaccine. Patient saw the doctor on 22Mar2021, 4 days after the second shot, for the numbness and tingling. The tingling had gone down from a 10 to a 6 or 7. Primary doctor said to hang in there. Has been having anxiety and palpitations. These symptoms occurred a week after the shot. She never thought about the shot. Patient received nothing for treatment of numbness and tingling. Was told to take Aleve, but nothing major. Has not been taking anything. Tomorrow at 2:00pm, has appointment with spine doctor to see what he thinks. Has never had tingling before with the back pain and no tingling in the arms. The adverse events require a visit to physician's office. Went Friday 09Apr2021 to doctor about numbness and tingling and was told she was due for her second dose of the pneumococcal vaccine. Stated that it wouldn't interfere with what was going on. The outcome of event "one arm was having tingling" was recovering, the outcome of other events was unknown. The case was reported as non-serious.  No follow-up attempts are needed. No further information is expected.