she is also immunocompromised; The caller noticed her leg was really wet and saw the callus had fallen off and since then its a big open wound, bright red, and definitely infected; she had red bumps all over her legs that progressed to itching and then scabbed over with a white fixed scab; she had red bumps all over her legs that progressed to itching and then scabbed over with a white fixed scab; she had red bumps all over her legs that progressed to itching and then scabbed over with a white fixed scab; with the white hard calluses but they are all oozing; her hair started falling out/has gotten worse since she has received the first dose of the vaccine.; The red spots got bigger and turned brown; The scabs have fallen off and it looks infected; the scab fell of and its dripping drainage. All of the spots are draining, even the ones with the callus on them; sick for about 5 days; experienced small red spots which turned into kind of like ulcers on her legs; This is a spontaneous report from a contactable consumer (patient). A 51-year-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot number: EP7534) via an unspecified route of administration, administered in Arm Right on 23Mar2021(age at the vaccination 51-year-old) as single dose for COVID-19 immunization. The patient condition was temporal arteries became blocked. The patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Batch/ lot EW0150 or EW0160) via an unspecified route of administration, administered on 14Apr2021 as signal for covid-19 immunisation. Medical history included polymyalgia rheumatica from Nov2019, giant cell arteritis from Nov2019 (Temporal arteries became blocked), uveitis (Diagnosed 8 months prior to Polymyalgia rheumatica and Giant cell arteritis). Concomitant medication(s) included prednisone (MANUFACTURER UNKNOWN); amlodipine besilate (MANUFACTURER UNKNOWN) dose of 5mg taken for blood pressure measurement; atorvastatin calcium (MANUFACTURER UNKNOWN) taken for blood cholesterol, (EFFEXOR)dose of 37.5mg, vitamin D for protect her bones from the steroids. The patient stated that on Feb 2021 having hair started falling out or 2 months before receiving the vaccine it was gotten worse since she has received the first dose of the vaccine. On 25Mar2021 had small red spots on her legs 2 days after the vaccine and she thought it was bed bugs, but she watched it and the next night she went to bed ad didn't wake up with any more spots. The red spots got bigger and turned brown and Within the first week after the vaccine experienced small red spots which turned into kind of like ulcers on her legs. After about a week the patient thought it was cancer, but the doctor said it wasn't. The spots started forming a big thick white callus on them. The patient brother thought it was psoriasis, the patches were very small and spread out all on the patient legs. The patient doctor said that the spots were not psoriasis. The patient was supposed to go to the dermatologist but didn't. on unknown date the spots remained all over her legs and were very itchy. The scabs have fallen off and it looks infected. The largest spot is about the size of a silver dollar and the scab fell of and its dripping drainage. she is also immunocompromised, and all of the spots are draining, even the ones with the callus on them. The patient doesn't think its pus because it's a clear fluid. The patient noticed her leg was really wet and saw the callus had fallen off and since then it's a big open wound, bright red, and definitely infected. The patient takes Actemoria which is a biologic for her autoimmune disorder. The patient was called her doctor and told them about this because she needs to stop her biologic and get on an antibiotic quickly. The spots happened after the first dose of the vaccine. The patient was sick for about 5 days and felt like she was on the worst boat ride of her life. The patient was fine after the second dose. The patient had not recovered from events was falling out/has gotten worse, he had red bumps all over her legs that progressed to itching and then scabbed over with a white fixed scab, small red spots which turned into kind of like ulcers on her legs, and outcome of the remaining events was unknown.    Information on Lot/Batch number was available. Additional information has been requested