This spontaneous case was reported by a patient and describes the occurrence of PAIN (Extreme pain/a lot of pain/everything hurts), SWELLING FACE (Whole face blew up), GRANULOMA ANNULARE (Granuloma annulare), VERTIGO (Vertigo) and COVID-19 (Got Covid after the booster) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. Concurrent medical conditions included Peanut allergy. On 06-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 13-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. In January 2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. In May 2022, the patient experienced VERTIGO (Vertigo) and COVID-19 (Got Covid after the booster). In 2022, the patient experienced PAIN (Extreme pain/a lot of pain/everything hurts), SWELLING FACE (Whole face blew up), GRANULOMA ANNULARE (Granuloma annulare), PAIN IN EXTREMITY (her leg hurt) and HEADACHE (Horrible headache). The patient was treated with BOTULINUM TOXIN TYPE A (BOTOX) at an unspecified dose and frequency. At the time of the report, PAIN (Extreme pain/a lot of pain/everything hurts), SWELLING FACE (Whole face blew up), GRANULOMA ANNULARE (Granuloma annulare), VERTIGO (Vertigo), COVID-19 (Got Covid after the booster), PAIN IN EXTREMITY (her leg hurt) and HEADACHE (Horrible headache) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In May 2022, SARS-CoV-2 test: (Positive) positive test in Mid month of May2022. It was reported that the patient was taking other medication (unspecified). It was reported that patient was assuming they were IM. It was reported that patient had vertigo with COVID. The patient was dealing with skin base condition which can develop from vaccine and take years to go away. Company comment: This spontaneous case concerns a 48-year-old female patient, with no medical history reported, who experienced the non-serious unexpected AESI COVID-19 approximately 4 months after receiving a booster dose of mRNA-1273 vaccine. First and second doses of mRNA-1273 vaccine were administered in an inappropriate schedule of vaccination (37 days interval). She had a COVID-19 test result positive. It was reported that after vaccine was given her whole face blew up and she was in extreme pain, had horrible headache, her leg hurt, and everything hurt. Two days after the vaccine she was diagnosed with granuloma annulare. She also got Covid. She stated now she is dealing with skin base condition which can develop from vaccine and take years to go away. The benefit risk relationship of mRNA-1273 vaccine is not affected by this report. This case was linked to MOD-2022-630480 (Patient Link). Sender's Comments: This spontaneous case concerns a 48-year-old female patient, with no medical history reported, who experienced the non-serious unexpected AESI COVID-19 approximately 4 months after receiving a booster dose of mRNA-1273 vaccine. First and second doses of mRNA-1273 vaccine were administered in an inappropriate schedule of vaccination (37 days interval). She had a COVID-19 test result positive. It was reported that after vaccine was given her whole face blew up and she was in extreme pain, had horrible headache, her leg hurt, and everything hurt. Two days after the vaccine she was diagnosed with granuloma annulare. She also got Covid. She stated now she is dealing with skin base condition which can develop from vaccine and take years to go away. The benefit risk relationship of mRNA-1273 vaccine is not affected by this report.