fainting episodes; POTS/pulse would go from 90-200; This spontaneous case was reported by a physician and describes the occurrence of SYNCOPE (fainting episodes) in an adult patient of an unknown gender who received mRNA-1273 (Spikevax) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On an unknown date, the patient received dose of mRNA-1273 (Spikevax) (unknown route) 1 dosage form. On an unknown date, the patient experienced SYNCOPE (fainting episodes) (seriousness criterion medically significant) and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS/pulse would go from 90-200). At the time of the report, SYNCOPE (fainting episodes) outcome was unknown and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS/pulse would go from 90-200) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Heart rate: 90-200 (High) 90-200.     The action taken with mRNA-1273 (Spikevax) (Unknown) was unknown.   For mRNA-1273 (Spikevax) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications was reported.  Reporter said they developed POTS and she treated them with IV fluids and have not fully recovered. She was not specific as to who but stated in general that their pulse would go from 90-200 and had fainting episodes at varying times.  Company Comment : This spontaneous case reported by a physician concerns an adult patient of unknown age and gender, with no medical history reported, who experienced the unexpected serious (medically significant) event of syncope and the unexpected, non serious adverse events of special interest, Postural Orthostatic Tachycardia syndrome (POTS), that occurred on an unknown date after receiving a dose of mRNA-1273 Vaccine on an unknown date. No concomitant medications was reported. Postural Orthostatic Tachycardia syndrome was treated with IV fluids and the physician reported that that the patient's pulse would go from 90-200 and had fainting episodes at varying times. Outcome of syncope was unknown and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) had not resolved. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   This case was linked to MOD-2022-531875 (Patient Link).; Sender's Comments: This spontaneous case reported by a physician concerns an adult patient of unknown age and gender, with no medical history reported, who experienced the unexpected serious (medically significant) event of syncope and the unexpected, non serious adverse events of special interest, Postural Orthostatic Tachycardia syndrome (POTS), that occurred on an unknown date after receiving a dose of mRNA-1273 Vaccine on an unknown date. No concomitant medications was reported. Postural Orthostatic Tachycardia syndrome was treated with IV fluids and the physician reported that that the patient's pulse would go from 90-200 and had fainting episodes at varying times. Outcome of syncope was unknown and POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) had not resolved. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.