Anxious / anxiousness; angry now, things are just really getting on her nerves / has anger; Blood pressure started going up; Headaches real bad; no patience / short patience; Really, really antsy; she is so sleepy; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 62 year-old female patient received bnt162b2 (BNT162B2), administered in arm right, administration date 19Feb2021 (Lot number: EN6201) at the age of 62 years as dose 1, single and administered in arm right, administration date 12Mar2021 (Lot number: EN6208) as dose 2, single for covid-19 immunisation. Relevant medical history included: "Anxiety", start date: 1998 (ongoing); "Depression" (ongoing), notes: probably before 1998.; "Esophageal varices" (unspecified if ongoing); "Anemic" (unspecified if ongoing); "Autoimmune" (unspecified if ongoing); "Liver Problems" (unspecified if ongoing), notes: Verbatim: Liver Problems; "Skin cancer" (unspecified if ongoing). Concomitant medication(s) included: ALPRAZOLAM. Past drug history included: Cipro, reaction(s): "bad reaction". The following information was reported: ANXIETY (non-serious) with onset 19Feb2021, outcome "not recovered", described as "Anxious / anxiousness"; ANGER (non-serious) with onset 19Feb2021, outcome "not recovered", described as "angry now, things are just really getting on her nerves / has anger"; BLOOD PRESSURE INCREASED (non-serious) with onset 19Feb2021, outcome "not recovered", described as "Blood pressure started going up"; HEADACHE (non-serious) with onset 19Feb2021, outcome "not recovered", described as "Headaches real bad"; IMPATIENCE (non-serious) with onset 19Feb2021, outcome "not recovered", described as "no patience / short patience"; RESTLESSNESS (non-serious) with onset 19Feb2021, outcome "not recovered", described as "Really, really antsy"; SOMNOLENCE (non-serious) with onset 19Feb2021, outcome "not recovered", described as "she is so sleepy". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of anxiety, anger, blood pressure increased, headache, impatience, restlessness, somnolence. Additional Information: Patient reported that she worked at the hospital for years back in 2000 and was on disability now. Her sister was a nurse. The patient's medical history (including any illness at time of vaccination), was also described as: No, nothing out of ordinary other than she was sick from the other thing that would cause alarm. She was trying to avoid dying from that. That's aggravating- just trying to stay alive. Patient had no family medical history relevant to adverse events. There were no relevant tests. Both doses of the vaccine were administered at around 9-9:15 AM. Patient has been taking Alprazolam (generic) for 23 years, and said because they help her; also stated that "its anything that gets her calmed down if she has to function and go somewhere.". It was reported that the patient was diagnosed with anxiety when she fell over at work and blood was pouring out of her head and she passed out at the hospital when leaving exit by the Emergency Room; the patient started spinning around and spun back in the doors and that's where they had to pick her up from. The patient had no history of all previous immunization with the Pfizer vaccine considered as suspect, no additional vaccines administered on same date of the Pfizer suspect and no prior vaccinations within 4 weeks. Clinical course of the events was as follows: After receiving the Pfizer Covid 19 Vaccine, the patient was real anxious or angry now, things were just really getting on her nerves, her blood pressure started going up, had headaches real bad, has anger and no patience and she was real, real antsy. The patient noticed these events on the same day of the first vaccine, Friday, 19Feb2021. She stated that they tried to relax that weekend. It was reported that the patient didn't worry too much about it on the second dose, but she still got the headaches and anxiousness and anger. Her blood pressure went up which she has to monitor daily because of other pre-existing conditions. The patient reported that she was a relatively pleasant person, not a mean person or angry person at all. She had short patience and it was out of character for her. The patient mentioned that she was so sleepy and she has been trying to do some things around the house. It was reported that all of these symptoms were still ongoing, especially the headaches and the anger. The patient stated that she does have anxiety and depression, which she already had that. It might of set something off, not to a point where she was screaming or yelling or anything like that. The patient also said that she doesn't want psychological problems worse than she already has.   No follow-up attempts are possible. No further information is expected.