Brain effects; Laziness; No motivation, no comprehension that I should get up and do something; Feel something strange at my eyes; Fatigue; Affecting my speech; This spontaneous case was received on 07-Nov-2023 from other non-healthcare professional (consumer) via Regulatory Authority (reference number: SEQW23-04077) and concerned an 83-year-old  female patient.   The patient's concurrent conditions included astigmatism, Crohn's disease, chronic obstructive pulmonary disease (COPD), asthma, Cryptococcus infection, pancreas problems (treated with Creon (pancreatin) and Loperamide with no good result, now stomach and pancreas won't work together), gastrointestinal reflux, incurvated spine and scoliosis, scalp infection, sensitivity to Benadryl (diphenhydramine hydrochloride) and oregano, lactose intolerance, and patient can't eat too much garlic, as reported '15 years ago someone in restaurant put way too much of it in a dish'. The patient historical condition included teeth pain, seizures (in the 90s), and unconsciousness after the surgery for three days. The patient's historical procedures included surgery to remove part of the intestine, and surgery for Chron's disease. The patient's historical vaccines included two doses of the Pfizer-BioNtech Covid-19 vaccine (tozinameran) after which the patient experienced having no memory of going back home, the patient thinks it damaged her brain functions, and an unspecified COVID-19 vaccine after which the patient experienced worsening of Chron disease and arthritis (hand and knuckles pain). The patient's concomitant medications were not reported.  On 24-Oct-2023, the patient was vaccinated with Fluad Quadrivalent (influenza vaccine inact sag 4v; dose: 0.5 ml, route of administration and anatomical location: not reported) for active immunization against influenza disease. The batch number was not reported.  On 27-Oct-2023, reported as '3 days after', three days after receiving Fluad Quadrivalent, the patient had brain effects, and experienced fatigue, laziness, no motivation, and comprehension that she should get up and do something. The patient also started to feel something strange in her eyes.  On an unspecified date in 2023, the patient felt like it was affecting her speech.   On 04-Nov-2023, reported as last Sunday, about 9 days after the shot, the patient started to get better but was still experiencing some fatigue. The patient reported that she felt like it was also affecting her speech, but it was also better now.  At the time of the initial reporting, the patient was recovering from all events.   The reporter assessed all events as related to Fluad Quadrivalent. The patient reported she has an adverse reaction on vaccine.   The event of 'Brain disorder NOS' was considered to be medically significant by a Physician within Regulatory Authority.  Company comment: An 83-year-old patient with medical history of astigmatism, Crohn's disease, chronic obstructive pulmonary disease, was vaccinated with Fluad Quadrivalent. On 27-Oct-2023, three days after receiving Fluad Quadrivalent, the patient had brain effects (as reported), and experienced fatigue, laziness, no motivation, and comprehension that she should get up and do something. On an unspecified date in 2023, the patient felt like it was affecting her speech. On 04-Nov-2023, the patient started to get better but was still experiencing some fatigue, and started to feel something strange in her eyes. Due to insufficient information provided about diagnostic findings and alternative aetiology, causal role of the suspect vaccine is unassessable for all events.; Reporter's Comments: The patient reported she has an adverse reaction on vaccine.; Sender's Comments: An 83-year-old patient with medical history of astigmatism, Crohn's disease, chronic obstructive pulmonary disease, was vaccinated with Fluad Quadrivalent. On 27-Oct-2023, three days after receiving Fluad Quadrivalent, the patient had brain effects (as reported), and experienced fatigue, laziness, no motivation, and comprehension that she should get up and do something. On an unspecified date in 2023, the patient felt like it was affecting her speech. On 04-Nov-2023, the patient started to get better but was still experiencing some fatigue, and started to feel something strange in her eyes. Due to insufficient information provided about diagnostic findings and alternative aetiology, causal role of the suspect vaccine is unassessable for all events.