My arm swelled up; I developed a very itchy rash; I developed a very itchy rash which was very painful; I was quite uncomfortable for about 4 days and I was resolved by six days; my right arm at injection site became inflammed; my right arm at injection site became painful; my right arm at injection side became red; my right arm at injection site became itchy; I was feeling fatigued; This spontaneous case was reported by a nurse and describes the occurrence of PERIPHERAL SWELLING (My arm swelled up), RASH PRURITIC (I developed a very itchy rash), PAIN (I developed a very itchy rash which was very painful), DISCOMFORT (I was quite uncomfortable for about 4 days and I was resolved by six days) and INJECTION SITE INFLAMMATION (my right arm at injection site became inflammed) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 027A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hypothyroidism and Drug allergy. Concomitant products included MAGNESIUM CITRATE, THYROID (THYTROPHIN PMG) from 03-Oct-2011 to an unknown date for Hypothyroidism, LEVOTHYROXINE and VITAMIN D NOS from 20-Mar-2021 to an unknown date for an unknown indication.    On 03-Mar-2021 at 8:10 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 15-Mar-2021, the patient experienced PERIPHERAL SWELLING (My arm swelled up). 15-Mar-2021, the patient experienced RASH PRURITIC (I developed a very itchy rash), PAIN (I developed a very itchy rash which was very painful), DISCOMFORT (I was quite uncomfortable for about 4 days and I was resolved by six days), INJECTION SITE INFLAMMATION (my right arm at injection site became inflammed), INJECTION SITE PAIN (my right arm at injection site became painful), INJECTION SITE ERYTHEMA (my right arm at injection side became red), INJECTION SITE PRURITUS (my right arm at injection site became itchy) and FATIGUE (I was feeling fatigued). On 16-Mar-2021, FATIGUE (I was feeling fatigued) had resolved. On 21-Mar-2021, PERIPHERAL SWELLING (My arm swelled up), RASH PRURITIC (I developed a very itchy rash), PAIN (I developed a very itchy rash which was very painful), DISCOMFORT (I was quite uncomfortable for about 4 days and I was resolved by six days), INJECTION SITE INFLAMMATION (my right arm at injection site became inflammed), INJECTION SITE PAIN (my right arm at injection site became painful), INJECTION SITE ERYTHEMA (my right arm at injection side became red) and INJECTION SITE PRURITUS (my right arm at injection site became itchy) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment interventions included a topical CBD essential oil, ointment, and an ice pack that was rotated with a warm pack and applied at the injection site.   This case was linked to MOD-2021-074017 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 09-Jul-2021: Follow-up received on 09-JUL-2021 and contains significant information updated patient demographics, past medical history, vaccine start date, route of administration, concomitant and treatment medications, updated events and event outcome