sunburn type of reaction; Dyspnoea; Erythema; Immediate post-injection reaction; Palpitations; Rash papular; Rash pruritic; Asthenia; Cardiac discomfort; Hypoaesthesia; rash across chest; Chills; dizzy; flushed; tightness in the chest; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of DIZZINESS (dizzy), FLUSHING (flushed), CHEST DISCOMFORT (tightness in the chest), RASH ERYTHEMATOUS (sunburn type of reaction) and DYSPNOEA (Dyspnoea) in a 43-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included MS (On infusion.) and Drug allergy (Allergic to Solumedrol Ceclor.). Concomitant products included NATALIZUMAB (TYSABRI) and TIZANIDINE for an unknown indication.   On 27-Feb-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 27-Feb-2021, the patient experienced DIZZINESS (dizzy), FLUSHING (flushed), CHEST DISCOMFORT (tightness in the chest), DYSPNOEA (Dyspnoea), ERYTHEMA (Erythema), IMMEDIATE POST-INJECTION REACTION (Immediate post-injection reaction), PALPITATIONS (Palpitations), RASH PAPULAR (Rash papular), RASH PRURITIC (Rash pruritic), ASTHENIA (Asthenia), CARDIAC DISCOMFORT (Cardiac discomfort), HYPOAESTHESIA (Hypoaesthesia), RASH (rash across chest) and CHILLS (Chills). On an unknown date, the patient experienced RASH ERYTHEMATOUS (sunburn type of reaction). At the time of the report, DIZZINESS (dizzy), FLUSHING (flushed), CHEST DISCOMFORT (tightness in the chest), DYSPNOEA (Dyspnoea), ERYTHEMA (Erythema), IMMEDIATE POST-INJECTION REACTION (Immediate post-injection reaction), PALPITATIONS (Palpitations), RASH PAPULAR (Rash papular), RASH PRURITIC (Rash pruritic), ASTHENIA (Asthenia), CARDIAC DISCOMFORT (Cardiac discomfort), HYPOAESTHESIA (Hypoaesthesia) and CHILLS (Chills) had not resolved and RASH ERYTHEMATOUS (sunburn type of reaction) and RASH (rash across chest) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 27-Feb-2021, Blood cannabinoids: unknown (Inconclusive) unknown. On 27-Feb-2021, Clostridium test: unknown (Inconclusive) Unknown. On 27-Feb-2021, Computerised tomogram: unknown (Inconclusive) Unknown. On 27-Feb-2021, Fibrin D dimer: normal (normal) normal. On 27-Feb-2021, Heart rate: 150 (High) HR 150. On 27-Feb-2021, Human chorionic gonadotropin: unknown (Inconclusive) Unknown. On 27-Feb-2021, Metabolic function test: unknown (Inconclusive) Unknown. On 27-Feb-2021, Thyroxine: unknown (Inconclusive) Unknown. On 27-Feb-2021, Troponin I: unknown (Inconclusive) Unknown. On 03-Mar-2021, Blood pressure measurement: 220/100 (High) BP 220/100. On 03-Mar-2021, Full blood count: unknown (Inconclusive) CBSC with automated diff Metabolic panel, basic Samples being held t4, free troponin-1 TSH 3rd generation. On 04-Mar-2021, Heart rate: 135 (High) 135 resting. On 11-Mar-2021, Angiogram: unknown (Inconclusive) CTA CHEST for PE DXR. On 11-Mar-2021, Chest X-ray: unknown (Inconclusive) Unknown. On 11-Mar-2021, Electrocardiogram: unknown (Inconclusive) EKG 12 Lead Lactale. On 11-Mar-2021, Heart rate: 155 (High) 155 and remained. On 11-Mar-2021, SARS-CoV-2 test: negative (Negative) COVID Negative. On 11-Mar-2021, Urine analysis: unknown (Inconclusive) Unknown.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Treatment included 100 mg IV Benadryl, 25 mg Pepcid, hydroxyzine and steroid taper   Most recent FOLLOW-UP information incorporated above includes: On 03-Mar-2021: Added medical history, lab data and  newevents.