symptoms and frequency increased/she woke up with worse symptoms; PVC (Premature Ventricular Contractions); shortness of breath; weakness; This spontaneous case was reported by a consumer and describes the occurrence of DYSPNOEA (shortness of breath), ASTHENIA (weakness), VENTRICULAR EXTRASYSTOLES (PVC (Premature Ventricular Contractions)) and CONDITION AGGRAVATED (symptoms and frequency increased/she woke up with worse symptoms) in a 68-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 939902) for COVID-19 vaccination.     No Medical History information was reported.    On 23-Aug-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 28-Aug-2021, the patient experienced DYSPNOEA (shortness of breath) (seriousness criterion hospitalization) and ASTHENIA (weakness) (seriousness criterion hospitalization). In September 2021, the patient experienced VENTRICULAR EXTRASYSTOLES (PVC (Premature Ventricular Contractions)) (seriousness criterion hospitalization). On 27-Sep-2021, the patient experienced CONDITION AGGRAVATED (symptoms and frequency increased/she woke up with worse symptoms) (seriousness criterion hospitalization). The patient was hospitalized for 1 day due to ASTHENIA, CONDITION AGGRAVATED, DYSPNOEA and VENTRICULAR EXTRASYSTOLES. At the time of the report, DYSPNOEA (shortness of breath), ASTHENIA (weakness), VENTRICULAR EXTRASYSTOLES (PVC (Premature Ventricular Contractions)) and CONDITION AGGRAVATED (symptoms and frequency increased/she woke up with worse symptoms) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 28-Aug-2021, Heart rate: irregular (Inconclusive) irregular.         On 02-Sep-2021 was her first emergency room visit. She went to the emergency room where they admitted her and kept her overnight. They sent her home the next day with beta blockers. Patient's husband was not sure about her concomitant medications either besides Pepcid.  This case concerns a 68-year-old female patient with no relevant medical history, who experienced the unexpected serious events of Dyspnoea,  Asthenia, and Ventricular extrasystoles. The events occurred approximately 6 days after receiving the third dose of Moderna COVID-19 Vaccine. The re-challenge was not applicable as the events occurred following the third dose of vaccine. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 27-Sep-2021: Follow up received contain patient demographic include date of birth, age, weight,  new event added , concomitant medication ,  drug information include batch number, case upgrade to serious .; Sender's Comments: This case concerns a 68-year-old female patient with no relevant medical history, who experienced the unexpected serious events of Dyspnoea,  Asthenia, and Ventricular extrasystoles. The events occurred approximately 6 days after receiving the third dose of Moderna COVID-19 Vaccine. The re-challenge was not applicable as the events occurred following the third dose of vaccine. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.