Blood Clots; Altered Speech; Body Is Stiff; Word Finding Difficulties; Left Eye Muscle Feels Gummy; Forgets What They Are Talking About; Nausea; periodic Stumbling/Left Leg Is Dragging; Unable To Draw A Clock For A Cognitive Exam; Afraid Of Being Alone; Lack Of Appetite; Depth Perception Issues; Headaches Everyday; This spontaneous case was reported by a consumer and describes the occurrence of THROMBOSIS (Blood Clots) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 039B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included WARFARIN for Clot blood, BUTALBITAL, CAFFEINE, PARACETAMOL (FIORICET), SUMATRIPTAN, CELECOXIB (CELEXA [CELECOXIB]), ETHINYLESTRADIOL, ETONOGESTREL (NUVARING) and BACLOFEN for an unknown indication.    On 20-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 20-Apr-2021, the patient experienced HEADACHE (Headaches Everyday). On 23-Apr-2021, the patient experienced ILLUSION (Depth Perception Issues), FEAR (Afraid Of Being Alone) and DECREASED APPETITE (Lack Of Appetite). On 30-Apr-2021, the patient experienced THROMBOSIS (Blood Clots) (seriousness criteria hospitalization and medically significant), GAIT DISTURBANCE (periodic Stumbling/Left Leg Is Dragging) and COGNITIVE DISORDER (Unable To Draw A Clock For A Cognitive Exam). On an unknown date, the patient experienced DYSARTHRIA (Altered Speech), MUSCULOSKELETAL STIFFNESS (Body Is Stiff), APHASIA (Word Finding Difficulties), ABNORMAL SENSATION IN EYE (Left Eye Muscle Feels Gummy), MEMORY IMPAIRMENT (Forgets What They Are Talking About) and NAUSEA (Nausea). The patient was hospitalized on 30-Apr-2021 due to THROMBOSIS. The patient was treated with ONDANSETRON ongoing since an unknown date for Nausea, at a dose of 1 UNK and HEPARIN for Clot blood, at an unspecified dose and frequency. At the time of the report, THROMBOSIS (Blood Clots), DYSARTHRIA (Altered Speech), MUSCULOSKELETAL STIFFNESS (Body Is Stiff), ILLUSION (Depth Perception Issues), GAIT DISTURBANCE (periodic Stumbling/Left Leg Is Dragging), APHASIA (Word Finding Difficulties), ABNORMAL SENSATION IN EYE (Left Eye Muscle Feels Gummy), FEAR (Afraid Of Being Alone), DECREASED APPETITE (Lack Of Appetite), MEMORY IMPAIRMENT (Forgets What They Are Talking About), COGNITIVE DISORDER (Unable To Draw A Clock For A Cognitive Exam), HEADACHE (Headaches Everyday) and NAUSEA (Nausea) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   The patient reports going to the emergency room on 25Apr2021 and was discharged with medication for the treatment of headaches. During the hospital stay, a MRV (Magnetic Resonance Venography) was conducted, however the results were not provided.  Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.   This case was linked to MOD-2021-211608 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.