pain; elevated blood pressure; elevated heart rate; tears are coming; severe chest pressure; becoming numb; shortness of breath; chest pain; head went down; beet-red chest discoloration; severe nausea; tingling in fingers; headache; don't feel good; flushed firm; This is a spontaneous report received from a contactable reporter(s) (Other HCP) from medical information team.  A 44 year-old female patient received bnt162b2 (BNT162B2) (Lot number: FK9729, Expiration Date: 21Jun2022) as dose 2 (booster), 0.3 ml single for covid-19 immunisation. Relevant medical history included: "diabetes" (unspecified if ongoing); "fibroid disorder" (unspecified if ongoing), notes: fibroid disorder; "back injury" (unspecified if ongoing); "latex" (unspecified if ongoing), notes: Allergic to latex; "Interchange of vaccine products" (unspecified if ongoing). The patient's concomitant medications were not reported. Past drug history included: Codeine, reaction(s): "Allergic to codeine", notes: Allergic to codeine. Vaccination history included: Janssen covid-19 vaccine (had a reaction "almost intubated but cannot be verified" 9Apr2021 (Lot 1808978).), administration date: 09Apr2021, when the patient was 44 years old, for COVID-19 Immunization, reaction(s): "shortness of breath". The following information was reported: PAIN (non-serious), outcome "unknown", described as "pain"; BLOOD PRESSURE INCREASED (non-serious), outcome "unknown", described as "elevated blood pressure"; HEART RATE INCREASED (non-serious), outcome "unknown", described as "elevated heart rate"; LACRIMATION INCREASED (non-serious), outcome "unknown", described as "tears are coming"; CHEST DISCOMFORT (non-serious), outcome "unknown", described as "severe chest pressure"; HYPOAESTHESIA (non-serious), outcome "unknown", described as "becoming numb"; DYSPNOEA (non-serious), outcome "unknown", described as "shortness of breath"; CHEST PAIN (non-serious), outcome "unknown", described as "chest pain"; HEAD DISCOMFORT (non-serious), outcome "unknown", described as "head went down"; SKIN DISCOLOURATION (non-serious), outcome "unknown", described as "beet-red chest discoloration"; NAUSEA (non-serious), outcome "unknown", described as "severe nausea"; PARAESTHESIA (non-serious), outcome "unknown", described as "tingling in fingers"; HEADACHE (non-serious), outcome "unknown", described as "headache"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "don't feel good"; FLUSHING (non-serious), outcome "unknown", described as "flushed firm". The events "pain", "elevated blood pressure", "elevated heart rate", "tears are coming", "severe chest pressure", "becoming numb", "shortness of breath", "chest pain", "head went down", "beet-red chest discoloration", "severe nausea", "tingling in fingers", "headache", "don't feel good" and "flushed firm" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: it was reported 11:50 AM Pulse 112, Manual Blood pressure 176/102, Respiration Rate 16, Oximeter reading O2 Saturation 100%, lungs clear, 0 wheezing. 11:55AM (every 5 min) - chest pain 7/10, headache, nausea, Pulse 103, Blood pressure 145/102, Respiration Rate 16, initiated emergency number call at that time, placed Patient on O2 2L per nasal canula, arrived in (name) life support unit - transferred to (name) medical. Nurse stated it was almost at the 15 minute mark, when she started having reaction. It was like Oh, nauseous, don't feel good. By the time she got the blood pressure 'cup' on her, heads down, tears are coming, feeling nauseous, hard to talk because of the nausea. Then she started complaining about the chest pressure, elevated blood pressure, elevated heart rate. You know the finger tingling and becoming numb from you know 'hyper thin lady'. She became extremely 'flushed firm' chest up even the medic said that does not looks like a normal cover (Not clarified). So 'that's why hospital she went'.   Follow-up attempts are completed. No further information is expected.