Pain in the legs below the knees; Veins wrapping; Swollen and bulging veins like Varicose veins; Muscle cramping; I have no energy; I do have a tiredness; Pain in the legs below the knees; This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (Pain in the legs below the knees), VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins), MUSCLE SPASMS (Muscle cramping) and ASTHENIA (I have no energy) in a 43-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014CQ1A and 037B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Penicillin allergy. Concomitant products included ESCITALOPRAM OXALATE (LEXAPRO) for Anxiolytic therapy, MULTIVITAMIN [VITAMINS NOS] for an unknown indication.   On 09-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 07-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PAIN IN EXTREMITY (Pain in the legs below the knees), VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins), MUSCLE SPASMS (Muscle cramping), ASTHENIA (I have no energy), FATIGUE (I do have a tiredness) and ARTHRALGIA (Pain in the legs below the knees). At the time of the report, PAIN IN EXTREMITY (Pain in the legs below the knees) and ARTHRALGIA (Pain in the legs below the knees) had resolved, VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins) and MUSCLE SPASMS (Muscle cramping) outcome was unknown and ASTHENIA (I have no energy) and FATIGUE (I do have a tiredness) had not resolved.            No treatment information was provided.   This case was linked to MOD-2021-163788 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 25-Jul-2021: Follow up information received included additional events, outcome of the events, demographic details, and medical history ('Tenderness' event removed from this case as it was experienced by the patient after first dose of the vaccine). This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (Pain in the legs below the knees), VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins), MUSCLE SPASMS (Muscle cramping) and ASTHENIA (I have no energy) in a 43-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014CQ1A and 037B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Penicillin allergy. Concomitant products included ESCITALOPRAM OXALATE (LEXAPRO) for Anxiolytic therapy, MULTIVITAMIN [VITAMINS NOS] for an unknown indication.   On 09-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 07-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PAIN IN EXTREMITY (Pain in the legs below the knees), VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins), MUSCLE SPASMS (Muscle cramping), ASTHENIA (I have no energy), FATIGUE (I do have a tiredness) and ARTHRALGIA (Pain in the legs below the knees). At the time of the report, PAIN IN EXTREMITY (Pain in the legs below the knees) and ARTHRALGIA (Pain in the legs below the knees) had resolved, VARICOSE VEIN OPERATION (Veins wrapping), VARICOSE VEIN (Swollen and bulging veins like Varicose veins) and MUSCLE SPASMS (Muscle cramping) outcome was unknown and ASTHENIA (I have no energy) and FATIGUE (I do have a tiredness) had not resolved.            No treatment information was provided.   This case was linked to MOD-2021-163788 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 25-Jul-2021: Follow up information received included additional events, outcome of the events, demographic details, and medical history ('Tenderness' event removed from this case as it was experienced by the patient after first dose of the vaccine).