Itching/Noticed this upon on shoulders and then was moving, later on the upper arms (left and right), Now it (itching) is on forearms, Some of it (itching, little bit of spread) around the right knee; Little bit of redness; Bumps/Noticed this on shoulders, then was moving, later on the upper arms (left and right), Now it (bumps) is on forearms, Some of it (bumps, little bit of spread) around the right knee; Blotchiness where the bumps are along with itching; This spontaneous case was reported by a patient and describes the occurrence of PRURITUS (Itching/Noticed this upon on shoulders and then was moving, later on the upper arms (left and right), Now it (itching) is on forearms, Some of it (itching, little bit of spread) around the right knee), ERYTHEMA (Little bit of redness), URTICARIA (Bumps/Noticed this on shoulders, then was moving, later on the upper arms (left and right), Now it (bumps) is on forearms, Some of it (bumps, little bit of spread) around the right knee) and RASH MACULAR (Blotchiness where the bumps are along with itching) in a 74-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 054A22A) for COVID-19 vaccination.     The patient does not have any allergies. The patient did not have a COVID positive test or a diagnosis.  Previously administered products included for Drug use for unknown indication: Johnson & Johnson vaccine (had received 2 doses of the Johnson & Johnson vaccine.). Past adverse reactions to the above products included No adverse event with Johnson & Johnson vaccine. Concomitant products included IBUPROFEN and OMEPRAZOLE (PRILOSEC [OMEPRAZOLE]) for an unknown indication.    On 26-May-2022, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .25 milliliter. In May 2022, the patient experienced PRURITUS (Itching/Noticed this upon on shoulders and then was moving, later on the upper arms (left and right), Now it (itching) is on forearms, Some of it (itching, little bit of spread) around the right knee), ERYTHEMA (Little bit of redness), URTICARIA (Bumps/Noticed this on shoulders, then was moving, later on the upper arms (left and right), Now it (bumps) is on forearms, Some of it (bumps, little bit of spread) around the right knee) and RASH MACULAR (Blotchiness where the bumps are along with itching). At the time of the report, PRURITUS (Itching/Noticed this upon on shoulders and then was moving, later on the upper arms (left and right), Now it (itching) is on forearms, Some of it (itching, little bit of spread) around the right knee) and URTICARIA (Bumps/Noticed this on shoulders, then was moving, later on the upper arms (left and right), Now it (bumps) is on forearms, Some of it (bumps, little bit of spread) around the right knee) had not resolved and ERYTHEMA (Little bit of redness) and RASH MACULAR (Blotchiness where the bumps are along with itching) outcome was unknown.            The patient received Moderna vaccine booster dose on 26-May-2022. The patient reported blotchiness where the bumps were along with itching. It was also reported that this was noticed upon on shoulders and then was moving and was later on the upper arms (left and right) but now it (bumps, itching) was on forearms, some of it (bumps, itching, little bit of spread) around the right knee. Patient wanted to know if these were side effects of the vaccine and how long these side effects would last. No treatment was received.