GAGS TRYING TO EAT; LEFT SHOULDER FEELING LIKE IT WAS BEING STABBED; TINGLING IN ARMS AND HAND; HANDS STARTED TO GO NUMB; BURNING SENSATION IN BACK BETWEEN SHOULDER BLADES THAT GOT REALLY BAD THAT SHOT DOWN TO FINGERS; LOSS OF ABILITY TO WALK/COULD NOT WALK (COLLAPSED); MUSCLE SPASM; CANNOT REALLY MOVE OR DO MUCH; LOSING APPETITE DUE TO POUNDING HEART/LOSE TO EAT; LOSING SLEEP DUE TO POUNDING HEART/ LOSE SLEEP; ANXIETY; HIGH INTENSE HEART PALPITATIONS/HEART RACING; ELEVATED HEART RATE; WAKE UP; This spontaneous report received from a patient concerned a 24 year old female. The patient's height and weight were not reported. The patient's past medical history included previous history of thyroid and covid-19 (on an unspecified date in NOV-2020) and concurrent conditions included history of anxiety and shoulder pain that started (about 3 months after covid-19 and had been on and off) and other pre-existing medical conditions included she had a family history of thyroid and heart conditions. The patient was previously treated with levothyroxine sodium for previous history of thyroid.  The patient received covid-19 vaccine ad26.cov2.s (Dose series in number 1) (suspension for injection, route of administration was not reported, batch number: unknown and expiry: unknown) dose was not reported, 1 total administered on 15-OCT-2021 to left arm for prophylactic vaccination. The batch number was not reported and has been requested. No concomitant medications were reported at the time of reporting.  On an unspecified date patient underwent laboratory test included: Blood test with result no thyroid, heart rate with result 150 {beats} per minute (min) and cardiology said not abnormal (normal) and 170 {beats} per min so on 10-DEC-2021, he was going to order another heart monitor for a longer time. She experienced left shoulder feeling like it was being stabbed and gags trying to eat. She was surviving on soft foods. On an unspecified date in NOV-2021, she experienced wake up. On 09-NOV-2021, she experienced elevated heart rate, high intense heart palpitations started at night and lasted for 24 hours. Called ambulance and was told may be was anxiety. She had heart palpitations ongoing during day and the night.  On 10-NOV-2021, she experienced losing appetite and losing sleep. Her symptoms were causing her to loose sleep and eat. On 20-NOV-2021 she visited the emergency room (ER) because they got real bad and underwent laboratory test included: Blood test, Computerised tomogram (CT) scan and Electrocardiogram (EKG) with result no heart abnormalities. Then they sent her home. But her heart racing persisted. On 23-NOV-2021, she saw a cardiologist and they put a portable EKG on her and told her to wear it for 24 to 48 hours and laboratory data included: EKG with result as not reported.  On an unspecified date she experienced cannot really move or do much.  On 07-DEC-2021, treatment medications included: Lexapro (escitalopram oxalate) for unknown indication. On 11-DEC-2021 (Saturday), she was in hospital again due to burning sensation in back between shoulder blades that got really bad that shot down to fingers, hands started to go numb, tingling in arms and hand. She then got driven to ER and experienced loss of ability to walk/could not walk (collapsed). So she waited for a room. Then the doctor checked back and said she had a muscle spasm but she feels like that was not correct. On an unspecified date additional treatment medications included: Tylenol (paracetamol) left shoulder feeling like it is being stabbed. She had visited physician office. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from loss of ability to walk/could not walk (collapsed) on 12-DEC-2021, was recovering from hands started to go numb, had not recovered from high intense heart palpitations/heart racing, elevated heart rate, losing appetite due to pounding heart/lose to eat, losing sleep due to pounding heart/ lose sleep, burning sensation in back between shoulder blades that got really bad that shot down to fingers, tingling in arms and hand, left shoulder feeling like it was being stabbed, and gags trying to eat, and the outcome of anxiety, muscle spasm, cannot really move or do much and wake up was not reported. This report was serious (Other Medically Important Condition). This case, from the same reporter is linked to 20211230564.; Sender's Comments: V0: 20211233831-COVID-19 VACCINE AD26.COV2.S-Loss of ability to walk/could not walk (collapsed), High intense heart palpitations/heart racing, Elevated heart rate. These events are considered unassessable. The events have a compatible/suggestive temporal relationship, are unlabeled, and have unknown scientific plausibility. There is no information on any other factors potentially associated with the events.