Sweating; Vaccination adverse reaction; Flaking skin; Viral infection; Leg pain; Chills; Psoriasis flare-up; Staphylococcal infection; This spontaneous case was reported by a consumer and describes the occurrence of PSORIASIS (Psoriasis flare-up), STAPHYLOCOCCAL INFECTION (Staphylococcal infection), HYPERHIDROSIS (Sweating), IMMUNISATION REACTION (Vaccination adverse reaction) and SKIN EXFOLIATION (Flaking skin) in a 49-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product RISANKIZUMAB RZAA (SKYRIZI [RISANKIZUMAB RZAA]) for Plaque psoriasis.    No Medical History information was reported.   On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form and third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. and RISANKIZUMAB RZAA (SKYRIZI [RISANKIZUMAB RZAA]) (Subcutaneous) 1 dosage form. On 16-Aug-2021, the patient experienced STAPHYLOCOCCAL INFECTION (Staphylococcal infection). On an unknown date, the patient experienced PSORIASIS (Psoriasis flare-up), HYPERHIDROSIS (Sweating), IMMUNISATION REACTION (Vaccination adverse reaction), SKIN EXFOLIATION (Flaking skin), VIRAL INFECTION (Viral infection), PAIN IN EXTREMITY (Leg pain) and CHILLS (Chills). At the time of the report, PSORIASIS (Psoriasis flare-up) and IMMUNISATION REACTION (Vaccination adverse reaction) had not resolved, STAPHYLOCOCCAL INFECTION (Staphylococcal infection) had resolved and HYPERHIDROSIS (Sweating), SKIN EXFOLIATION (Flaking skin), VIRAL INFECTION (Viral infection), PAIN IN EXTREMITY (Leg pain) and CHILLS (Chills) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       Concomitant Drugs Not Reported.  On unknown dates, the patient experienced psoriasis flare on leg, sweat, chills, felt reaction with Moderna booster vaccine, flakes, virus and leg switching and pain. on 16 aug 2021, the patient experienced staphylococcal infection. On an unknown date, staphylococcal infection resolved. Moderna covid-19 vaccine (Elasomeran) was also considered suspect.  The patient had psoriasis and it was continued. He never had psoriasis to improve since started. He had itchiness all over and in scalp. He saw flakes and forty-four hours flare on leg. He had staphylococcal infection and a virus that included sweat and chills for twenty-four hours. His leg was switching and pain. He felt reaction with vaccine. It was unknown if patient was enrolled in a COVID-19 Vaccine Trial.   The reporter's causality for the event(s) of psoriasis flare on leg, staphylococcal infection, sweat, chills, flakes, virus and leg switching and pain was not provided. The reporter's causality for the event(s) of felt reaction with moderna booster vaccine with SKYRIZI(RISANKIZUMAB) was a reasonable possibility.  Treatment Drugs Not Reported.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in   Reporter did not allow further contact