Severe Pruritus/ local itching or pruritus; Red rash/ local redness and rash; Hives; Raised area develops; Has severely impacted my quality of life especially loss of quality sleep; Allergic reaction; Unavoidably scratching; Felt like poisen ivey but without raised expanding blisters; This spontaneous case was reported by an other health care professional and describes the occurrence of PRURITUS (Severe Pruritus/ local itching or pruritus), RASH ERYTHEMATOUS (Red rash/ local redness and rash), URTICARIA (Hives), SWELLING (Raised area develops) and INSOMNIA (Has severely impacted my quality of life especially loss of quality sleep) in a 73-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 040A21A and 016M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Type 2 diabetes mellitus since 1999, Asthma, Hay fever and Drug allergy (Anectine allergy- Stopped breathing during surgery) since 1985.   On 12-Feb-2021 at 2:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 21-Mar-2021 at 2:00 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 13-Mar-2021 at 8:00 AM, the patient experienced PRURITUS (Severe Pruritus/ local itching or pruritus), RASH ERYTHEMATOUS (Red rash/ local redness and rash), SWELLING (Raised area develops) and INSOMNIA (Has severely impacted my quality of life especially loss of quality sleep). 13-Mar-2021 at 8:00 AM, the patient experienced URTICARIA (Hives), ALLERGIC REACTION TO EXCIPIENT (Allergic reaction), SCRATCH (Unavoidably scratching) and VACCINATION COMPLICATION (Felt like poisen ivey but without raised expanding blisters). The patient was treated with PREDNISONE for Allergic reaction, at an unspecified dose and frequency. At the time of the report, PRURITUS (Severe Pruritus/ local itching or pruritus), RASH ERYTHEMATOUS (Red rash/ local redness and rash), URTICARIA (Hives), SWELLING (Raised area develops), INSOMNIA (Has severely impacted my quality of life especially loss of quality sleep), ALLERGIC REACTION TO EXCIPIENT (Allergic reaction), SCRATCH (Unavoidably scratching) and VACCINATION COMPLICATION (Felt like poisen ivey but without raised expanding blisters) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered PRURITUS (Severe Pruritus/ local itching or pruritus), RASH ERYTHEMATOUS (Red rash/ local redness and rash) and URTICARIA (Hives) to be possibly related. No further causality assessments were provided for SWELLING (Raised area develops), INSOMNIA (Has severely impacted my quality of life especially loss of quality sleep), ALLERGIC REACTION TO EXCIPIENT (Allergic reaction), SCRATCH (Unavoidably scratching) and VACCINATION COMPLICATION (Felt like poisen ivey but without raised expanding blisters).    No concomitant medication provided by the reporter. Treatment medications included antihistamines and steroids.  Dermatologist prescribed steroid injections that worked temporarily.  Itchy on the forearms then progressed to the neck and shoulders. The patient stated that the steroids prescribed were raising blood glucose. The itchy rash continued for five months with no end in sight.  The patient never experienced the more common redness or pain at injection site. No fever or other symptoms commonly reported.   Most recent FOLLOW-UP information incorporated above includes: On 16-Aug-2021: Reporters contact details, patients demographics, medical history, treatment medication added and event verbatim updated to include hives, local pruritus, local erythema and local rash.