During the week of 12/27/21 I then also developed left knee, ankle, and foot pains; I had severe tenderness and pain in my left hand, mostly in the palm of my hand/ sore in my palm/ I sometimes get jolts pains in my hand/ foot pains/ pain in my leg and foot increases throughout the work week; It was difficult to make a fist; Sometimes a slight tingling that radiates towards my elbow/ some tingling that felt similar to the sensations I get in my hand and forearm/ It sometimes feels like pins and needles on my foot and radiates towards my knee; Dose received: 3; This is a spontaneous report received from contactable reporter (Other healthcare professional). The reporter is the patient.  A 41-year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in left arm, administration date 15Dec2021 at 15:45 (Lot number: FD7218) at the age of 41 years as dose 3 (booster), single for COVID-19 immunisation. Relevant medical history included: "Chronic back pain" (unspecified if ongoing) and "Spider vein" (unspecified if ongoing), notes: Spider veins in both legs. There were no concomitant medications. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE; Lot Number: UNKNOWN; Anatomical Location: Left arm; Route of Administration: Unspecified; Administration time: 10:00), administration date: an unknown date in Dec2020, when the patient was 40 years old, for COVID-19 immunisation and Bnt162b2 (DOSE 2, SINGLE; Lot Number: UNKNOWN; Anatomical Location: Left arm; Route of Administration: Unspecified; Administration time: 10:00), administration date: an unknown date in Jan2021, when the patient was 40 years old, for COVID-19 immunisation. The following information was reported: IMMUNISATION (non-serious) with onset 15Dec2021 at 15:45, outcome "unknown", described as "Dose received: 3"; PAIN IN EXTREMITY (non-serious) with onset 16Dec2021 at 07:00, outcome "not recovered", described as "I had severe tenderness and pain in my left hand, mostly in the palm of my hand/ sore in my palm/ I sometimes get jolts pains in my hand/ foot pains/ pain in my leg and foot increases throughout the work week"; MUSCULOSKELETAL STIFFNESS (non-serious) with onset 16Dec2021 at 07:00, outcome "not recovered", described as "It was difficult to make a fist"; PARAESTHESIA (non-serious) with onset 16Dec2021 at 07:00, outcome "not recovered", described as "Sometimes a slight tingling that radiates towards my elbow/ some tingling that felt similar to the sensations I get in my hand and forearm/ It sometimes feels like pins and needles on my foot and radiates towards my knee"; ARTHRALGIA (non-serious) with onset 27Dec2021, outcome "not recovered", described as "During the week of 12/27/21 I then also developed left knee, ankle, and foot pains". The events "I had severe tenderness and pain in my left hand, mostly in the palm of my hand/ sore in my palm/ I sometimes get jolts pains in my hand/ foot pains/ pain in my leg and foot increases throughout the work week", "It was difficult to make a fist", "Sometimes a slight tingling that radiates towards my elbow/ some tingling that felt similar to the sensations I get in my hand and forearm/ It sometimes feels like pins and needles on my foot and radiates towards my knee" and "During the week of 12/27/21 I then also developed left knee, ankle, and foot pains" were evaluated at the physician office visit. Therapeutic measures were not taken as a result of pain in extremity, musculoskeletal stiffness, paraesthesia and arthralgia.  Additional information: The patient had no known allergies. Prior to vaccination, the patient was not diagnosed with COVID-19. The patient did not receive any other vaccines within four weeks prior to the COVID vaccine. Since the vaccination, the patient had not been tested for COVID-19. It was reported that after several days the tenderness decreased but it still felt sore in her palm to that day (at the time of this report). She stands at work almost all day long so the pain in her leg and foot increases throughout the work week.