She had the first Pfizer COVID vaccine on 02Feb2021 and her mouth swelled up terribly; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 74 year-old female patient received bnt162b2 (BNT162B2), administration date 02Feb2021 (Lot number: EL8982, Expiration Date: May2021) at the age of 74 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Bad reaction to iodine contrast dye" (unspecified if ongoing), notes: went into respiratory arrest numerous times; "Allergic to like gobs of medications" (unspecified if ongoing); "Allergic to different antibiotics" (unspecified if ongoing); "She cannot have sulfa drugs" (unspecified if ongoing), notes: She couldn't even administer Mucamist to her patients because of the sulfa in it. There are certain antibiotics she cannot take.; "Allergic to certain foods" (unspecified if ongoing); "She can't take penicillin" (unspecified if ongoing); "Allergic to the preservative in the flu vaccine" (unspecified if ongoing); "COVID", start date: 25Apr2020 (unspecified if ongoing); "She has had problems in the past with allergies" (unspecified if ongoing), notes: She has had problems in the past with allergies where she has ended up on ventilators. There were no concomitant medications. The following information was reported: MOUTH SWELLING (non-serious) with onset 2021, outcome "unknown", described as "She had the first Pfizer COVID vaccine on 2 Feb 2021 and her mouth swelled up terribly".  Additional information: She had the first Pfizer COVID vaccine on 02Feb2021 and her mouth swelled up terribly. She took a Benadryl before. No UPC/lot/expiration provided. She pretty much knew she had a lot of allergies to drugs so they told her to get it done at the hospital. Within 15 minutes, she opened her mouth, and the doctor said the roof of her mouth was swelled. She was 75 now. She has had problems in the past with allergies where she has ended up on ventilators. She had a bad reaction to iodine contrast dye, the old version. She went into respiratory arrest numerous times every time when they tried to give it to her. She doesn't have the NDC/lot/expiration. She was allergic to like gobs of medications. She doesn't have any NDC/lot/expiration for any of the medications. That was years ago. She was allergic to different antibiotics. She even saw a top specialist at the Clinic for her allergies. She said she knows what medications to stay away from. She cannot have sulfa drugs. She couldn't even administer mucamist to her patients because of the sulfa in it. There are certain antibiotics she cannot take. She can't take penicillin. Overall, in general, she knows what she can and can't take. She was allergic to certain foods. She was allergic to the preservative in the flu vaccine. She had a problem at the hospital one time. She had a severe reaction when she was working. The new one doesn't have preservative in it so she can get that. Her doctor was nutty, and was insisting she get the booster shot. She has read that if the patient has a reaction to the COVID vaccine to not get it anymore. Her first dose of the COVID vaccine was on 1Feb2021, with lot number EL8982, and expiration May2021. The problem was she has more education than her doctor does. Her doctor wants her to get the booster. She had COVID 25Apr2020. She has recovered completely from all allergic reactions. She was still tired all the time since she had COVID virus. She sleeps a lot. She was also still more achy than normal. She was a very active female. She doesn't look her age at all. She does yoga and goes to the gym daily. She was still active. Caller declined to get over to medical information.   No follow-up attempts are possible. No further information is expected.