Sjogren's reaction worsening; Sjogren's reaction worsening; total dryness throughout the body; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 78-year-old female patient received BNT162b2 (BNT162B2), on 26Feb2021 as dose 1, single (Lot number: EN6202) at the age of 78 years for covid-19 immunisation. The patient's relevant medical history included: "Raynauds" (ongoing), notes: Raynauds; "Pulmonary hypertension" (ongoing), notes: Pulmonary hypertension. Diagnosed this fall was borderline for years and now over the borderline.; "Scleroderma" (ongoing), notes: At the same time she was diagnosed with Hashimoto's thyroiditis, probably 34 years ago; "Hashimoto's thyroiditis" (ongoing), notes: Hashimoto's thyroiditis. Diagnosed about 34 years ago; "Sjogren's" (ongoing), notes: Sjogren's Reaction Diagnosed between 20 and 30 years ago.; "environmentally allergic" (ongoing), notes: environmentally allergic Diagnosed about 34 years ago.; "High blood pressure" (unspecified if ongoing), notes: High blood pressure; "Rash" (unspecified if ongoing); "Dry mouth" (unspecified if ongoing); "Dry eyes" (unspecified if ongoing); "Probiotic" (unspecified if ongoing), notes: Probiotic; "Anemia" (unspecified if ongoing); "GERD from scleroderma" (unspecified if ongoing), notes: GERD from scleroderma; "Arrhythmia due to crest heart" (unspecified if ongoing), notes: Arrhythmia due to crest heart. Concomitant medication(s) included: SYNTHROID taken for autoimmune thyroiditis (ongoing); FLECAINIDE taken for arrhythmia, start date: 2018 (ongoing); OMEPRAZOLE taken for gastrooesophageal reflux disease (ongoing); LOSARTAN taken for hypertension (ongoing); RESTASIS taken for dry eye (ongoing); ASPIRIN (E.C.); MAGNESIUM GLYCINATE; D3; VITAMIN C [ASCORBIC ACID] taken for rash; RUTIN [RUTOSIDE] taken for rash; ALIGN taken for probiotic therapy. Vaccination history included: Shingles vaccine (severe reaction to a shingles vaccine prior to the COVID-19 vaccine), for Immunization, reaction(s): "severe reaction". The following information was reported: SJOGREN'S SYNDROME (medically significant), CONDITION AGGRAVATED (medically significant) all with onset Feb2021, outcome "not recovered" and all described as "Sjogren's reaction worsening"; DRY SKIN (non-serious) with onset Feb2021, outcome "unknown", described as "total dryness throughout the body".  Clinical course: Triamcinolone Acetonide cream: Dosage text: 0.1%, apply twice daily up to two weeks per month as needed. Synthroid: Taken for years. Thyroid was removed before receiving vaccines. Flecainide Probably 5 years ago, Omeprazole: Taken for decades, Losartan: A long time ago, probably 10 years. Restasis: Started: Probably 6 or 7 years ago Dosage text: twice a day 0.5%.  Align used as probiotics, Ocusoft lid scrub used Dry eyes, Biotene toothpaste used for Dry mouth, Biotene mouthwash used for Dry mouth. Had the COVID-19 Vaccine. Clarified that she had three Pfizer products, the first two and then another one. Each time she had a COVID-19 Vaccine she had a Sjogren's reaction and other symptoms that appeared at the same time which she hadn't had before. Was told by her immunologist and neurologist that the reactions are due to the COVID-19 Vaccines most likely. Patient Age: Happened right after she got the first shot 2 or 3 years ago. Clarified she got her first COVID-19 vaccine 26Feb2021. Sjogren's reaction worsening: Start Date: Within 24 hours after her first COVID-19 Vaccine she had total dryness throughout the body. Is now better but is still worse than it was before the COVID-19 vaccines. Now her mouth doesn't get enough moisture.Having a more difficult time with pills and food sticking in her mouth and trouble dislodging it. Raynaud's: Clarified she had Raynaud's before receiving the COVID-19 Vaccines. Had Raynaud's with her crest form scleroderma for 30 years but the COVID-19 vaccines made her conditions a lot worse. Her eyes were dryer and she was getting eye injections. Had to see and ophthalmologist. Most of it has resolved back to more of an eyedrop routine. Dryer eyes started after the COVID-19 Vaccine Booster and is ongoing but improved. clarified she was always on an eyedrop routine but then had the vision issues and infections after the vaccine booster but got it taken care of with steroid drops and has resolved at the moment. Did have a severe reaction to a shingles vaccine prior to the COVID-19 vaccine and was advised not to take a second shingles vaccine. Supposedly it was reported by her pharmacist already. Specific product name and manufacturer: Unknown. Had gotten the old shingles vaccine and was recommended to get the new one and then couldn't do the second dose. NDC/LOT/EXPIRY: Unknown.