Diagnosed with small Pericardial Effusion/1 week later diagnosed with large  Pericardial Effusion; 1 week later diagnosed with Pleural Effusion; Feeling sick; Feeling tiredness; Coughing blood; This spontaneous case was reported by a consumer and describes the occurrence of PERICARDIAL EFFUSION (Diagnosed with small Pericardial Effusion/1 week later diagnosed with large  Pericardial Effusion), HAEMOPTYSIS (Coughing blood), PLEURAL EFFUSION (1 week later diagnosed with Pleural Effusion), MALAISE (Feeling sick) and FATIGUE (Feeling tiredness) in a 29-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 037B21A) for COVID-19 vaccination.     No Medical History information was reported.    On 17-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 04-Jul-2021, the patient experienced HAEMOPTYSIS (Coughing blood) (seriousness criterion hospitalization). On an unknown date, the patient experienced PERICARDIAL EFFUSION (Diagnosed with small Pericardial Effusion/1 week later diagnosed with large  Pericardial Effusion) (seriousness criteria hospitalization and medically significant), PLEURAL EFFUSION (1 week later diagnosed with Pleural Effusion) (seriousness criterion hospitalization), MALAISE (Feeling sick) (seriousness criterion hospitalization) and FATIGUE (Feeling tiredness) (seriousness criterion hospitalization). The patient was treated with AZITHROMYCIN (ZITHROMAX) for Adverse event, at an unspecified dose and frequency; LEVOFLOXACIN (LEVAQUIN) for Adverse event, at an unspecified dose and frequency and IVERMECTIN for Adverse event, at an unspecified dose and frequency. At the time of the report, PERICARDIAL EFFUSION (Diagnosed with small Pericardial Effusion/1 week later diagnosed with large  Pericardial Effusion), PLEURAL EFFUSION (1 week later diagnosed with Pleural Effusion), MALAISE (Feeling sick) and FATIGUE (Feeling tiredness) outcome was unknown and HAEMOPTYSIS (Coughing blood) had not resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       Concomitant medication was not reported.  Treatment medication also include Zithromax, Levaquin, Ivermectin, and methozine.  Patient had difficulty in breathing due to her allergies. She was diagnosed with small Pericardial Effusion and was discharge. Then 1 week later she was re-admitted into hospital with Pericardial Effusion but this time it was large in size and also diagnosed with Pleural Effusion(fluid around the lungs).  Company Comment: This is a 29-year-old female patient who experienced hemoptysis, pleural effusion, and pericardial effusion among others after 1st dose of mRNA-1273. Very limited information regarding this event has been provided at this time. Details including date of vaccination of 2nd dose, diagnosis/discharge summary is required for further assessment.; Sender's Comments: This is a 29-year-old female patient who experienced hemoptysis, pleural effusion, and pericardial effusion among others after 1st dose of mRNA-1273. Very limited information regarding this event has been provided at this time. Details including date of vaccination of 2nd dose, diagnosis/discharge summary is required for further assessment.