THREE DIFFERENT AUTOIMMUNE DISEASES; FELT TERRIBLE AFTER SECOND MODERNA VACCINE; FEVER; BAD HEADACHE; This spontaneous case was reported by a consumer and describes the occurrence of AUTOIMMUNE DISORDER (THREE DIFFERENT AUTOIMMUNE DISEASES) in a  patient of an unknown age and gender who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product PANCREATIN (CREON) for Cystic fibrosis pancreatic.    Concurrent medical conditions included Immunocompromised (The patient did not have a spleen, already compromised immune system.).   On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form and first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. and PANCREATIN (CREON) (Oral) at an unspecified dose. On an unknown date, the patient experienced AUTOIMMUNE DISORDER (THREE DIFFERENT AUTOIMMUNE DISEASES) (seriousness criterion medically significant), FEELING ABNORMAL (FELT TERRIBLE AFTER SECOND MODERNA VACCINE), PYREXIA (FEVER) and HEADACHE (BAD HEADACHE). At the time of the report, AUTOIMMUNE DISORDER (THREE DIFFERENT AUTOIMMUNE DISEASES), PYREXIA (FEVER) and HEADACHE (BAD HEADACHE) outcome was unknown and FEELING ABNORMAL (FELT TERRIBLE AFTER SECOND MODERNA VACCINE) had resolved.            No concomitant product use was reported.  All doses of moderna vaccine including booster administered one in once.  No treatment information was provided.  The reporters causality with creon(pancreatin) for the events of three different autoimmune diseases, fever, felt terrible after second moderna vaccine and bad headache was not provided.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company comment: This is a spontaneous case reported by a consumer. An immunocompromised patient of an unknown age and gender in treatment with Pancreatin for Cystic fibrosis exocrine pancreatic insufficiency, received 3 doses of mRNA-1273 vaccine and experienced medically significant event of autoimmune disorder (reported as 3 different autoimmune diseases). Vaccination dates and onset date of the event were not provided, latency cannot be assessed. In addition, patient had fever, bad headache and felt terrible for a few days after the second dose of mRNA-1273 vaccine and the same thing happened after booster shot. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case reported by a consumer. An immunocompromised patient of an unknown age and gender in treatment with Pancreatin for Cystic fibrosis exocrine pancreatic insufficiency, received 3 doses of mRNA-1273 vaccine and experienced medically significant event of autoimmune disorder (reported as 3 different autoimmune diseases). Vaccination dates and onset date of the event were not provided, latency cannot be assessed. In addition, patient had fever, bad headache and felt terrible for a few days after the second dose of mRNA-1273 vaccine and the same thing happened after booster shot. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.