2 days after her second Pfizer COVID-19 Vaccine shot, she had terrible nausea. She said the nausea was like morning sickness or being punched in the stomach; Stomach ache; She had terrible depression. She said she had a history of depression and took medication for the depression; She was having trouble expressing herself and speaking. She found it very difficult to find words during a conversation; her cognitive issues had gotten worse after the second Pfizer COVID-19 Vaccine dose; she was having trouble processing information since her second Pfizer COVID-19 Vaccine shot. She said things get jumbled easily; This is a spontaneous report from a contactable consumer (patient). This 57-year-old female consumer reported for herself that she received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot number: UNKNOWN) via an unspecified route of administration on 09Mar2021 (at the age of 57-year-old female) as single dose for COVID-19 immunisation. The patient medical history included depression for at least 30 years and breast prosthesis user. She said when she takes her medicine, Fluoxetine, she could not even tell she had depression. She had been on Fluoxetine for a decade. She had breast implants placed from about 31 years ago and wondered if her old breast implants triggered an immune response. She grasped at straws to try and figure out what was going on. On an unspecified date in 2021, with her first Pfizer COVID-19 Vaccine, she only had a little fatigue, clarifying the fatigue was very slight. Concomitant medications were not reported. The patient previously took she her first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Batch/Lot number: UNKNOWN) via an unspecified route of administration on an unspecified date in 2021. The patient reported that her doctor encouraged her to report adverse side effects that happened after the second Pfizer COVID-19 Vaccine shot. She said that she was okay on 10Mar2021. On 11Mar2021, two days after her second vaccine shot, she had terrible nausea and stomach ache. She clarified the nausea was like morning sickness or being punched in the stomach and that her nausea had nothing to do with her bowels. In Mar2021, she said maybe the next day, she had terrible depression. She clarified of having a history of depression and took medication for it. She said it had been about a month since the nausea and depression started and she felt she had just turned the corner on both of them. Reported she had not been feeling too depressed since 14Apr2021 (last Wednesday). In Mar2021, she started having cognitive issues, struggling with words and following instructions since Dec2020. She was having trouble expressing herself and speaking as well. She found it very difficult to find words during a conversation. She also had trouble processing information and things got jumbled easily. Her cognitive issues worsened. She had been to see so many doctors with her nausea and enquired if other people had complained about terrible nausea and depression after receiving the vaccine. She was advised to be transferred to Pfizer Medical Information for further assistance with her questions. She said she was a teacher and had not gone to school since 08Mar2021 because she was so depressed and sick to her stomach. Report was not related to a study or programme. No further details provided. The outcome of events stomach ache and having trouble expressing herself and speaking was unknown while rest of all events outcome was not recovered.  Information about lot/batch number was requested.