severe chest pain; difficultly breathing; chest tightness; sinus pain/pressure; brain fog; low grade fever; This case was received via an unknown source (no reference has been entered for a health authority or license partner) on 15-Mar-2021 and was forwarded to Moderna on 17-Mar-2021.    This spontaneous case was reported by a consumer and describes the occurrence of CHEST PAIN (severe chest pain), DYSPNOEA (difficultly breathing), CHEST DISCOMFORT (chest tightness), SINUS PAIN (sinus pain/pressure) and FEELING ABNORMAL (brain fog) in a 27-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 007M20A and 001A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Depression in 2010 and Anxiety in 2005. Concurrent medical conditions included Food allergy (crab, scallops, squid.) and Allergy (grass, pollen, pet dander and anaphylactic reaction to some kind of fish at age of 2 years.). Concomitant products included VENLAFAXINE from 15-Apr-2016 to an unknown date for Depression.   On 06-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 06-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Mar-2021, the patient experienced PYREXIA (low grade fever). On 21-Mar-2021, the patient experienced FEELING ABNORMAL (brain fog). On an unknown date, the patient experienced CHEST PAIN (severe chest pain), DYSPNOEA (difficultly breathing), CHEST DISCOMFORT (chest tightness) and SINUS PAIN (sinus pain/pressure). The patient was treated with FLUTICASONE PROPIONATE, SALMETEROL XINAFOATE (WIXELA INHUB) for Dyspnea, at an unspecified dose and frequency; FORMOTEROL FUMARATE, MOMETASONE FUROATE (DULERA) for Dyspnea, at a dose of 2 UNK; ACETYLCYSTEINE (NAC [ACETYLCYSTEINE]) at an unspecified dose and frequency; RESVERATROL at an unspecified dose and frequency and MELATONIN at an unspecified dose and frequency. At the time of the report, CHEST PAIN (severe chest pain), CHEST DISCOMFORT (chest tightness) and SINUS PAIN (sinus pain/pressure) outcome was unknown and DYSPNOEA (difficultly breathing), FEELING ABNORMAL (brain fog) and PYREXIA (low grade fever) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 05-Jan-2021, Polymerase chain reaction: (Positive) positive for COVID-19..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   other treatment medications was vitamin c, coQ-10, probiotics, vitamin D, omega fish oil, turmeric, iron, sea moss gel, calcium, magnesium ,zinc, skullcap tincture, apple cider vinegar, ginger. ozone therapy, acupressure during anxiety episodes, IV therapy, infrared sauna.   Most recent FOLLOW-UP information incorporated above includes: On 07-Jun-2021: follow-up received on 7 June 2021.concomitant medications was updated.laboratory tests was updated.vaccine facility details updated.medical history details updated.second dose details updated.treatment details updated.