low iron level/iron levels were very low; average male hemoglobin was supposed to be 13.5, and his dropped to 10.5 initially; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 65-year-old male patient received BNT162b2 (BNT162B2), on 20Sep2021 as dose 3 (booster), single (Lot number: FF8841) at the age of 64 years for covid-19 immunisation. The patient's relevant medical history was not reported. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Batch/Lot number: EL9261, NDC/EXP: not provided.), administration date: 31Jan2021, when the patient was 64-year-old, for COVID-19 immunization, reaction(s): "Iron low"; BNT162b2 (DOSE 2, SINGLE, Batch/Lot number: EN6200), administration date: 21Feb2021, when the patient was 64-year-old, for COVID-19 immunization, reaction(s): "Iron low". The following information was reported: BLOOD IRON DECREASED (medically significant), outcome "unknown", described as "low iron level/iron levels were very low"; HAEMOGLOBIN DECREASED (medically significant), outcome "unknown", described as "average male hemoglobin was supposed to be 13.5, and his dropped to 10.5 initially". The patient underwent the following laboratory tests and procedures: Blood iron: low/very low; Haemoglobin: 10.5, notes: dropped to 10.5 initially; Low, notes: It was so low. Therapeutic measures were taken as a result of blood iron decreased, haemoglobin decreased.  Clinical course: No other conditions and no other products. Investigations were yes. Reportedly, serious was no. Pfizer COVID 19 Vaccine, primary adult series confirmed with patient. Patient was asking if Pfizer had any information with correlation of low iron levels with the Pfizer COVID 19 Vaccine. The patient was not complaining, and he noted that this was more of an informational thing. Patient stated he had started correlating his low iron when he got his Pfizer vaccine, got the vaccine over 1 year ago. He noted that he has searched on google despite it not being reliable. He states that there was no medical correspondence or study that has been done regarding low iron after having had the Pfizer COVID 19 Vaccine. He stated hundreds of people saying the same thing that they were perfectly fine and healthy and 30-45 days after the Pfizer they were tired and iron levels were depleted and this was never the case before. The patient felt that this may be in Pfizers best interest to look at that and do a study. The patient stated this coming Thursday will be his 12th infusion of iron, plus taking OTC iron supplements three times a day. Stated 12 infusions when you have to go to an oncology lab, and they put an IV in you and sit there for an hour while they load you with iron was quite a bit and there were enough people in his mind that have the same issue, he would think Pfizer wants to look into it. His doctors are aware of what was going on and doctor has looked it up to and there was no correlation and no study. The patient was calling about Pfizer COVID-19 vaccine, the original one. He believed that there could be kind of a correlation with it after he had it well over a year ago now, within the last year or 11 months. He had been a normal 66-year-old, a normal healthy guy, normal with no issues. He went to a routine checkup and did not connect the two, went to a normal routine medical thing and they noticed his iron levels were very low. They have monitored those for a year, and they are still low enough that he takes over the counter iron supplements, and now he has also started getting iron infusions. His low iron levels corresponded to the time he started taking Pfizer COVID-19 vaccine, and he looked for medical information about this and did not find anything concrete, which he was not saying that this happened because of Pfizer COVID-19 vaccine, but he did a generic search of the internet and found 100s of 100s of anecdotal stories saying the same thing happened to them within 30-45 days of the vaccine, they have depleted iron and doctors can't find out why their iron was depleted, and happened after Pfizer vaccination so he wanted to follow up and let people know, if Pfizer wanted to do an analysis after vaccination. Once your iron is gone, it is gone, you will have to try to maintain it with over-the-counter supplements etcetera. He wanted to see if Pfizer would look into this, all you have to do is google Pfizer vaccine and iron to definitely see literally hundreds say the same things, healthy fine males and females who cant pinpoint why their iron was suddenly depleted. No further details provided about males or females stories he found in his google search. The adverse event low iron level, he stated that this this started about 30-40 days after his first vaccine in Mar2021, and when they first started noticing they did not correlate it with the vaccine. He did not know his iron level for that time. For treatment, they first started him on iron supplements over the counter, 36.5mg once a day. Now they have him on three times a day, after they had him on twice a day. He has been having low iron for a year, and his iron was so bad recently that he had to have infusions. He does not know the lab values for his low iron. The patient said the only other thing was that for the average male hemoglobin was supposed to be 13.5, and his dropped to 10.5 initially, so they were not overly worried, it was not good, but it was not bad. He wanted to see if there was a known correlation or if Pfizer was aware of it.