injection site is large 3-inch circle that is swollen and hot; injection site is large 3-inch circle that is swollen and hot; at home sick; flu-like symptoms; received Covid vaccine booster 03DEC21; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team.  A 51 year-old female patient received bnt162b2 (BNT162B2), administration date 03Dec2021 (Batch/Lot number: unknown) at the age of 50 years as dose 3 (booster), single for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: Bnt162b2 (Dose: 1, Product name: Pfizer COVID-19 vaccine, Batch/lot number: Unknown), administration date: Mar2021, for Covid-19 immunization; Bnt162b2 (Dose: 2, Product name: Pfizer COVID-19 vaccine, Batch/lot number: Unknown), administration date: 2021, for Covid-19 immunization. The following information was reported: IMMUNISATION (non-serious) with onset 03Dec2021, outcome "unknown", described as "received Covid vaccine booster 03DEC21"; INJECTION SITE SWELLING (non-serious), INJECTION SITE WARMTH (non-serious) all with onset 05Dec2021, outcome "not recovered" and all described as "injection site is large 3-inch circle that is swollen and hot"; INFLUENZA LIKE ILLNESS (non-serious) with onset 04Dec2021, outcome "not recovered", described as "flu-like symptoms"; ILLNESS (non-serious) with onset 05Dec2021, outcome "unknown", described as "at home sick".  Additional information: Reporter is unhappy that MI cannot give treatment recommendations for his wife, stating that he spent 30 minutes on the phone with DSU giving data and he was led to understand that he would be receiving treatment guidance from Medical Information and stated he is "very displeased" and "feels it is very misleading". Reporter said that his wife is sick and is having a reaction. The patient got her Pfizer COVID-19 booster shot Friday, and their question is she is having severe flu symptoms which they know is a common reaction of the shot, and their concern is at the injection site she has a fever, it is swollen, and has a large 3 inch red circle. He says he may not be able to provide all requested information because his wife is at home sick, and he is not at that location. Pfizer COVID-19 vaccine NDC/LOT/EXP unknown, caller doesn't have his wife's vaccine card to provide that information at this time. The patient started having basic symptoms Saturday evening, but the arm and all of the more major symptoms really started yesterday about one to two in the afternoon, and have continued to get worse. The patient didn't do any treatment because she didn't want to irritate it more. He said for the routine flu symptoms she has done whatever you do for flu, they are not really concerned about those. He said her first dose he thought was Mar this year, and he thought that dose was followed up with in Jun or something like that, he is not sure with original doses. He clarified that his question is, is this a reaction to the site since they have heard that you can get normal flu symptoms but hadn't heard of people getting this fever at the spot of injection.  The lot number for bnt162b2 was not provided and will be requested during follow up.