lower right arm cramped and in pain; 5 digits in the right hand were numb; 2 digits from ulnar nerve worse than the others, they are stiff, have less feeling, and more numb; lower right arm cramped and in pain; This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (lower right arm cramped and in pain), HYPOAESTHESIA (5 digits in the right hand were numb), MUSCULOSKELETAL STIFFNESS (2 digits from ulnar nerve worse than the others, they are stiff, have less feeling, and more numb) and MUSCLE SPASMS (lower right arm cramped and in pain) in a 73-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 010M20A and 012L20A) for COVID-19 vaccination.     The patient's past medical history included Dialysis (patient is on dialysis because kidney function is not good.) since an unknown date. Concurrent medical conditions included Diabetes and Kidney disorder (kidney function is not good, this is the reason he took the booster shot). Concomitant products included INSULIN for Diabetes.   On 15-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 12-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In February 2021, the patient experienced PAIN IN EXTREMITY (lower right arm cramped and in pain), HYPOAESTHESIA (5 digits in the right hand were numb), MUSCULOSKELETAL STIFFNESS (2 digits from ulnar nerve worse than the others, they are stiff, have less feeling, and more numb) and MUSCLE SPASMS (lower right arm cramped and in pain). The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) for Adverse event, at a dose of 3 gram once a day. At the time of the report, PAIN IN EXTREMITY (lower right arm cramped and in pain), HYPOAESTHESIA (5 digits in the right hand were numb), MUSCULOSKELETAL STIFFNESS (2 digits from ulnar nerve worse than the others, they are stiff, have less feeling, and more numb) and MUSCLE SPASMS (lower right arm cramped and in pain) was resolving.            After the second dose, about 48-56 hours later, the patient woke up in the middle of the night and experienced the symptoms. The patient reported that with carpal tunnel syndrome, it effects the thumb, middle finger, and it has to do with the median nerve. It does not affect the ring finger or the ulnar nerve.He consulted a neurologist, an MRI and EMG did not show significant findings, however results were not provided.  Company comment: This case concerns a 73-year-old, male patient, with no relevant medical history, who experienced the non-serious, unexpected events of pain in extremity,  hypoesthesia, musculoskeletal stiffness and muscle spasms. The events occurred  approximately 2 days after second dose of mRNA 1273 vaccine. The patient felt pain in his lower right arm, cramps, with stiffness and numbness in his fingers. He consulted a neurologist, an MRI and EMG did not show significant findings, however results were not provided. The rechallenge is not applicable as events have not fully recovered. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.   This case was linked to MOD-2021-378345 (Patient Link).; Sender's Comments: This case concerns a 73-year-old, male patient, with no relevant medical history, who experienced the non-serious, unexpected events of pain in extremity,  hypoesthesia, musculoskeletal stiffness and muscle spasms. The events occurred  approximately 2 days after second dose of mRNA 1273 vaccine. The patient felt pain in his lower right arm, cramps, with stiffness and numbness in his fingers. He consulted a neurologist, an MRI and EMG did not show significant findings, however results were not provided. The rechallenge is not applicable as events have not fully recovered. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.