Patient had Covid infection twice; This spontaneous case was reported by a nurse and describes the occurrence of COVID-19 (Patient had Covid infection twice) in a 27-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     No Medical History information was reported.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced COVID-19 (Patient had Covid infection twice). At the time of the report, COVID-19 (Patient had Covid infection twice) outcome was unknown. Not Provided      For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were reported. Reporter stated that patient was not immunocompromised, patient had Covid infection twice. Patient did not receive monoclonal antibody therapy and received his primary Covid vaccine series by Moderna greater than 6 months ago. Patient had Covid infection twice, the first time was mild and second infection was on 22 September 21 and was pretty significant causing him to be down and out for 10 days. Patient had fever for 2-3 days. No treatment medications were reported. This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company comment  This is a spontaneous case reported by a nurse, concerning a 27 year old male patient, with no medical history reported, who experienced the unexpected, non serious AESI event of COVID 19, unknown days after  receiving the 2 dose of mRNA-1273 Vaccine in the covid 19 vaccination series. Patient previously received the 1 dose of Moderna vaccine on an unknown date. Reporter stated that patient was not immunocompromised, Patient did not receive monoclonal antibody therapy and received his primary Covid vaccine series by Moderna greater than 6 months ago. Patient had Covid infection twice, the first time it was mild and second infection was quite significant causing him to be down for 10 days. Patient had fever for 2-3 days. Details of risk factors, co morbidities, clinical course, concomitant medications and treatment details were not reported. The outcome of covid 19 was unknown. Ongoing Covid 19 pandemia could be considered as confounder to the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case reported by a nurse, concerning a 27 year old male patient, with no medical history reported, who experienced the unexpected, non serious AESI event of COVID 19, unknown days after  receiving the 2 dose of mRNA-1273 Vaccine in the covid 19 vaccination series. Patient previously received the 1 dose of Moderna vaccine on an unknown date. Reporter stated that patient was not immunocompromised, Patient did not receive monoclonal antibody therapy and received his primary Covid vaccine series by Moderna greater than 6 months ago. Patient had Covid infection twice, the first time it was mild and second infection was quite significant causing him to be down for 10 days. Patient had fever for 2-3 days. Details of risk factors, co morbidities, clinical course, concomitant medications and treatment details were not reported. The outcome of covid 19 was unknown. Ongoing Covid 19 pandemia could be considered as confounder to the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.