Scratchy throat; Minor rash all over the body (light colored); Fatigue; Swollen glands; Fever of 100.4 F°; Like getting a cold; Hard to breathe like when you go for a run: that you have trouble breathing but are still getting air/Heavy breathing; Swollen face; This spontaneous case was reported by an other health care professional and describes the occurrence of NASOPHARYNGITIS (Like getting a cold), DYSPNOEA (Hard to breathe like when you go for a run: that you have trouble breathing but are still getting air/Heavy breathing), SWELLING FACE (Swollen face), OROPHARYNGEAL PAIN (Scratchy throat) and RASH (Minor rash all over the body (light colored)) in a 64-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 046A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Supraventricular tachycardia, Flu (three weeks before the first dose she experienced a different kind of flu), Labored breathing, Headache, Nauseated, Ear ringing, Head cold, Glands swollen, Throat sore, Cardiac therapeutic procedure in January 1993 and Splenectomy on 24-Jul-1994. Concurrent medical conditions included Tachycardia, Immunocompromised ((Spleen removed)) since 24-Jul-1994, Hypersensitivity, Latex allergy (Lifelong : GLOVES will in few minutes turn my hands orange and cause breathing problems, TAPE causes rash.) since 20-Feb-1957, Sulfonamide allergy (10 yrs old : 104 fever, rash, delirious, monitored by Doctor.), Fish allergy (Allergic to Anchovies : causes Severe Rash), Lactose intolerance (Allergic to lactose causes bloating, cramps, diarrhea.) and Drug allergy (Allergic to Sulfa : Was 55+ yrs old, 2ND TIME TOOK SULFA : 103 fever, FULL-BODY RASH, need EMERG.ROOM IV's for 6+ hrs.). Concomitant products included DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) and NAPROXEN SODIUM (ALEVE) for an unknown indication.    On 20-Mar-2021 at 3:30 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 20-Mar-2021, the patient experienced NASOPHARYNGITIS (Like getting a cold), DYSPNOEA (Hard to breathe like when you go for a run: that you have trouble breathing but are still getting air/Heavy breathing), SWELLING FACE (Swollen face), RASH (Minor rash all over the body (light colored)), FATIGUE (Fatigue), LYMPHADENOPATHY (Swollen glands) and PYREXIA (Fever of 100.4 F°). On an unknown date, the patient experienced OROPHARYNGEAL PAIN (Scratchy throat). On 25-Apr-2021, DYSPNOEA (Hard to breathe like when you go for a run: that you have trouble breathing but are still getting air/Heavy breathing) had resolved. At the time of the report, NASOPHARYNGITIS (Like getting a cold), SWELLING FACE (Swollen face), OROPHARYNGEAL PAIN (Scratchy throat), RASH (Minor rash all over the body (light colored)), FATIGUE (Fatigue), LYMPHADENOPATHY (Swollen glands) and PYREXIA (Fever of 100.4 F°) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 20-Mar-2021, Body temperature: 100.4 f° (High) 100.4 F°.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered DYSPNOEA (Hard to breathe like when you go for a run: that you have trouble breathing but are still getting air/Heavy breathing) to be possibly related. No further causality assessments were provided for NASOPHARYNGITIS (Like getting a cold), SWELLING FACE (Swollen face), OROPHARYNGEAL PAIN (Scratchy throat), RASH (Minor rash all over the body (light colored)), FATIGUE (Fatigue), LYMPHADENOPATHY (Swollen glands) and PYREXIA (Fever of 100.4 F°).    No concomitant medications were provided by the reporter. No Treatment information was reported.   This case was linked to MOD-2021-211666 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 28-Sep-2021: Follow up received and contains Relevant medical history updated. Anatomical location  updated in product tab, Event outcomes, reporter's causality updated in event assessment.