swollen lymph nodes (lymphadenopathy)/swollen lymph nodes under her under arm/whole time in her neck; Discomfort pain; sharp stabbing pains in upper left quadrant/body aches; Abdominal pain; pain in her head, neck, and abdomen; vomiting; congestion; Upper respiratory symptoms; fatigue/Chronic fatigue; fever; chills; headache/headaches every day/most time its in front but it has also been in the back of her head, its throbbing and pounding pain/ On good day the patient's headache pain is 5/10/ bad day its 10/10; coughing; sore throat; body shake; lost 7 pounds; sedimentary rate is running high; white blood cell count is high; 2 Rash situations where she started running a fever and developed a rash, neck, and chest.; The patient's Fibrinogen was really low on the last test.; lower abdominal pain - achy/lower center of her abdomen which is more achey/doubled over laying in the floor; upper abdominal pain - tender to touch and sharp sometimes/upper left quadrant which is tender to touch and at times has stabbing pains there/doubled over laying in the floor; inflammation throughout her body; This is a spontaneous report from two contactable consumers (patient's parents). A 15-year-old female (reporter's daughter) patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm on 05Jun2021 (Lot Number: ER8734) at age of 15-year-old as DOSE 2, SINGLE for covid-19 immunisation.  There was no medical history. There were no concomitant medications. Historical vaccine included 1st dose of bnt162b2 (lot number: ER8731) on 15May2021 in arm at age of 15-year-old for covid-19 immunisation. After 1st dose, she experienced respiratory symptoms and went to the pediatrics office on 17May2021. Respiratory symptoms included sore throat, coughing, blood tinged mucus when she coughed. These symptoms lasted a few days then the patient was fine. On the evening of 05Jun2021 the night after she got her 2nd dose, she had fever, chills, body aches, headache, coughing, sore throat, fatigue that lasted longer than the 1st dose. Their daughter experienced chronic fatigue, she was wiped out and that's unusual for her this happened the month of June to July. On 23Aug2021, she had vomiting, headache, fatigue and body aches again. The side effects come and go since August, there's spike of fever every now and then. Their daughter also keeps having 2 kinds of abdominal pain, lower abdominal pain - achy, upper abdominal pain - tender to touch and sharp sometimes and was showing inflammation throughout her body. Caller also added that they've been to all kinds of tests for their daughter's discomfort pain, swollen lymph nodes (lymphadenopathy) but it's not going away, their daughter also went to ET on 2 separate occasions and was also hospitalized at one point for 3 days. The patient was in hospital for Abdominal pain: 27Oct2021 to 29Oct2021. Additionally, the patient was having all kinds of strange things happen. The patient has seen multiple doctors, been to urgent care, the emergency room and admitted to the hospital for three days. The patient has had every test done. The patient had lost 7 pounds. The patient was athletic but she was losing weight. The evening of 05Jun2021, the patient had fever, chills, body shake, headache, coughing, sore throat, and fatigue which all lasted longer than after the first dose. The patient was feeling fatigued pretty much all summer and the caller thought it was because the patient was working with her husband but now the caller was thinking its from the vaccine.   On 21Aug2021 when things started up again and hasn't gone away since. On 21Aug2021 the patient had a sore throat, congestion, and upper respiratory symptoms. The patient was tested for covid and strep as part of the rule out. The patient went to her pediatrician on 23Aug2021. 7 days later the patient wasn't improving and went back to the pediatrician because she was vomiting, had a headache, fatigue, and body aches going on. Since all of this started in August the caller doesn't know what symptoms will show up for the day in the patient. The patient has had fevers off and on, vomiting off and on. The patient has had swollen lymph nodes the whole time in her neck. The patient had a biopsy of the lymph nodes done. The doctors have ruled out a bunch of stuff but doesn't know what's going on with the patient but is thinking it s the vaccine. The patient also has swollen lymph nodes under her under arm and abdominal pain. The patient has had two different types of abdominal pain- one in the lower center of her abdomen which is more achey and then one in the upper left quadrant which is tender to touch and at times has stabbing pains there. The patient has headaches every day, most of the time its in the front but it has also been in the back of her head, its a throbbing and pounding pain. On a good day the patient's headache pain is 5/10 but on a bad day its 10/10. The caller has been tracking the patient's pain in her head, neck, and abdomen since 15Oct2021. Investigations: The patient has seen and ENT, rheumatologist, hematologist, infectious disease, and a neuro ophthalmologist. The patient has had CT scans- 2 of her neck and head and 2 of her abdomen. The second CT scan of the patient's abdomen was also and angio. The doctors were trying to rule out an abscess of the patient's tonsils. They did an MRI of the patient's head, neck, and brain to rule out tumors. They did an echo, EKG, ultrasound of the patient's abdomen, ultrasound of the patient's chest, a chest and neck x-ray. The patient has had blood work, every test. 80 tubes of blood has taken on the patient over the course of this time. The lab work showed that the patient's inflammation markers are elevated. The patient's C reactive protein was 2.1. The doctors are trying to figure out what is going on that doesn't fit into a category of anything particular. The patient's sedimentary rate is running high, her white blood cell count is high, CB19 cells are high, CD8T cells are high. Investigations: The patient's inflammatory markers have been elevated- platelets, C reactive proteins, sedimentary rate, RDW and everything that shows extreme inflammation has been elevated the whole time. The one phase the patient went through she had high white blood cell counts. None of the patient's labs have been sky high but they have been consistently elevated. The patient has had lymphadenopathy in her neck. The pain sensations in the patient's abdomen and lymph nodes, they haven't been able to pinpoint all of this. The doctor mentioned that they have seen a couple of patients with spleenitis but that was not seen on the patient's CT scans. The patient had 2 Rash situations where she started running a fever and developed a rash, neck, and chest. At first the caller thought it was a reaction to the Azithromycin antibiotic that she took. The patient only took one tablet and the doctor told her to stop taking them. The patient hadn't had a rash until today where she spiked a fever last couple of days. The rash was from the patient's neck and everywhere. The patient is not currently on any medications.  The immune mediated reaction is going on through the patient's body. The patient had a biopsy of the lymph nodes because they were afraid it was cancer. The biopsy showed CD4 and CD8 immunoglobulins had double negative receptors and the doctors were concerned about a particular HELPS but the patient was negative. Those markers are supposed to be about 10% and the patient's was at 6 % so they were checking that for awhile but it was negative. The patient's biopsy was negative for infection and cancer. Since this started, the patient has had a low grade but big immunological reaction. When all of this happened they were in and out of the pediatrician's office. The abdominal pain was bad and one night the patient was doubled over laying in the floor. The patient is tough and it takes a lot for her to get like this. The patient went to the emergency room that night, 30Sep2021, and stayed over night. The patient came home and they did more tests. The patient ended back in the emergency room again on 07Oct2021, and stayed 2 nights. This happened 6-8 weeks into this. Dr. (withheld) has been calling and speaking with the hematologist and running all of these tests. The patient's Fibrinogen was really low on the last test.  On 15Oct2021 the patient went into the emergency room during the day and was discharged and was back later that night because of the fever and abdominal pain. They were there over night that night and left after 7 am on 16Oct2021. On 19Oct2021 the patient had her lymph node biopsy. The patient was hospitalized 27Oct2021 until 29Oct2021 because of the sharp stabbing pains in upper left quadrant. Azithromycin- Lot and NDC unknown. Expiration date 15Oct2022. The patient only took one dose. The outcome of events sharp stabbing pains in upper left quadrant/body aches, swollen lymph nodes, Discomfort pain, fatigue, fever, chill, headache, coughing, sore throat, vomiting and neck pain   was not recovered. The outcome of rash was recovered. The outcome of other events was unknown.