Sensitive skin; General pain; My skin hurts; At first my alopecia started to get better, but then it stopped; Pain in her bladder area that started a couple weeks ago.; Pain in her lower back that started a couple weeks ago.; when I woke up this morning, I felt worse; Lack of covid antibodies following Moderna 2 dose series vaccination. States when I woke up this morning, I felt worse. Xeljanz xr is not working as well as it did at first.; my hands are in trouble and in pain; Headache; This spontaneous case was reported by a patient and describes the occurrence of SENSITIVE SKIN (Sensitive skin), PAIN (General pain), PAIN OF SKIN (My skin hurts), ALOPECIA (At first my alopecia started to get better, but then it stopped) and BLADDER PAIN (Pain in her bladder area that started a couple weeks ago.) in an adult female patient who received mRNA-1273 (Spikevax) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product TOFACITINIB CITRATE (XELJANZ XR) for an unknown indication.    No Medical History information was reported.   On an unknown date, the patient received second dose of mRNA-1273 (Spikevax) (unknown route) 1 dosage form On an unknown date, received first dose of mRNA-1273 (Spikevax) (unknown route) dosage was changed to 1 dosage form. and TOFACITINIB CITRATE (XELJANZ XR) (Oral) 11 milligram once a day. On an unknown date, the patient experienced SENSITIVE SKIN (Sensitive skin), PAIN (General pain), PAIN OF SKIN (My skin hurts), ALOPECIA (At first my alopecia started to get better, but then it stopped), BLADDER PAIN (Pain in her bladder area that started a couple weeks ago.), BACK PAIN (Pain in her lower back that started a couple weeks ago.), FEELING ABNORMAL (when I woke up this morning, I felt worse), DRUG INTERACTION (Lack of covid antibodies following Moderna 2 dose series vaccination. States when I woke up this morning, I felt worse. Xeljanz xr is not working as well as it did at first.), PAIN IN EXTREMITY (my hands are in trouble and in pain) and HEADACHE (Headache). At the time of the report, SENSITIVE SKIN (Sensitive skin), PAIN (General pain), PAIN OF SKIN (My skin hurts), ALOPECIA (At first my alopecia started to get better, but then it stopped), BLADDER PAIN (Pain in her bladder area that started a couple weeks ago.), BACK PAIN (Pain in her lower back that started a couple weeks ago.), PAIN IN EXTREMITY (my hands are in trouble and in pain) and HEADACHE (Headache) had not resolved and FEELING ABNORMAL (when I woke up this morning, I felt worse) and DRUG INTERACTION (Lack of covid antibodies following Moderna 2 dose series vaccination. States when I woke up this morning, I felt worse. Xeljanz xr is not working as well as it did at first.) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, SARS-CoV-2 antibody test: Lack of COVID antibodies following Moderna 2 dose series vaccination.     For mRNA-1273 (Spikevax) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were reported.  Reported that XELJANZ XR first shipped on 02-JUN-2021 (Xeljanz XR) Action taken: No action taken.  No treatment medications were reported.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.