nausea; vomit; fever; chills; weakness; This is a spontaneous report received from a contactable reporter(s) (Other HCP) from medical information team, Program ID. The reporter is the patient.  A 69-year-old female patient received BNT162b2 (BNT162B2), on 14Apr2022 as dose 4 (booster), single (Lot number: FJ4991) at the age of 69 years, in left deltoid for covid-19 immunisation. The patient's relevant medical history included: "Addison's disease" (ongoing). The patient took concomitant medications. Vaccination history included: BNT162b2 (Dose 1 of the Covid Vaccine: Administered to the caller on 21Jan2021; Lot Number: EL1284), administration date: 21Jan2021, when the patient was 68-year-old, for Covid-19 immunization; BNT162b2 (Dose 2 of the Covid Vaccine: Administered to the caller on 11Feb2021; Lot Number: EN5318), administration date: 11Feb2021, when the patient was 68-year-old, for Covid-19 immunization; BNT162b2 (Dose 3 (Booster) of the Covid Vaccine: Administered to the caller on 11Oct2021; Lot Number: 30155DA.), administration date: 11Oct2021, when the patient was 68-year-old, for Covid-19 immunization; Flu vaccines (Caller states that she gets Flu vaccines yearly and gets fatigue for one day. Dates, Lot Numbers, Expiry Dates for Flu Vaccines was unknown.), for Immunization, reaction(s): "gets fatigue for one day". The following information was reported: CHILLS (non-serious) with onset 15Apr2022, outcome "recovered" (15Apr2022); PYREXIA (non-serious) with onset 15Apr2022, outcome "recovered" (15Apr2022), described as "fever"; NAUSEA (non-serious) with onset 15Apr2022, outcome "recovered" (15Apr2022); VOMITING (non-serious) with onset 15Apr2022, outcome "recovered" (15Apr2022), described as "vomit"; ASTHENIA (non-serious) with onset 15Apr2022, outcome "recovered" (15Apr2022), described as "weakness". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: It was reported that the patient had no investigations relevant tests. The patient did not have any prior vaccinations within four weeks prior to the first administration date of the suspect vaccine. Caller stated that she got Flu vaccines yearly and got fatigue for one day. Dates, NDC, Lot Numbers, Expiry Dates for Flu Vaccines was unknown by the caller. The patient did not administer additional vaccines on same date of the Pfizer suspect. The patient reported that she had her last covid booster on 14Apr2022, about 12 hours after the vaccine, she had nausea, vomiting, fever, chills, and weakness. Time the vaccination was given was reported as around 1000. Caller stated that all of these symptoms began in the early morning on 15Apr2022 and lasted for around 8-10 hours. She was scheduled to have another booster on 21Oct2022. Stated that she was going to be getting her fifth shot, third booster vaccine this Friday. Her question was, was it safe for her to have another booster. The caller was wondering if with this new variant vaccine has anyone reported these same side effects. When prompted for specific seriousness criteria related to all of her symptoms the caller replied with no. Caller stated that she did have Addison's disease and was diagnosed with this condition about 27 years ago when she was about 42 years old and was on unspecified steroid medications. Stated that anything that dehydrates her, like vomiting, she usually has to go to the Emergency Room. States that she did not have to go to the Emergency Room or physician office with these above-mentioned events that started on 15Apr2022. Caller denied any other medications, labs, testing, or treatments relevant to these events.