patient had complaints of numbness and tingling in her right arm/numbness and tingling in both arms/and legs; patient had complaints of numbness and tingling in her right arm/numbness and tingling in both arms/and legs; This is a spontaneous report from a contactable nurse reported that a female patient of an unspecified age received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number was not reported), administered in arm left on an unspecified date then received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number was not reported) on 16Apr2021; both via an unspecified route of administration as a single dose for covid-19 immunisation. The vaccine was administered at the clinic. The patient's medical history and concomitant medications were not reported. The nurse reported that a patient received the 1st dose of the Pfizer covid vaccine approximately 21 days ago. It was given in her left arm. Within the 1st 15 minutes, the patient had complaints of numbness and tingling in her right arm. Her symptoms resolved by the next day. The patient has come back today for 2nd dose and has had an amplified response not just in 1 arm but in both arms within 15 minutes of observation. She did not report any other symptoms. Five minutes after, the patient said she had numbness and tingling in her legs. They kept her for about an hour eventually and she called someone to drive her home as a precaution. The nurse further reported that the patient who had numbness and tingling in the opposite arm from the arm that the first vaccine was administered in. The same patient came back for the second dose and felt numbness and tingling again. It has been said that the effects can be amplified on the second dose. This time, the numbness and tingling not only happened in one arm, but in both arms. Also had numbness and tingling in the legs. The patient did not experience any other side effects. No difficulty breathing, no swallowing issues, no dizziness or nausea, no vision changes, did not feel like she was going to pass out, and was not diaphoretic. Is a little concerning. Said she can find where she was spatially and can ambulate normally. Her concern was, is it going to increase, is it going to affect her breathing. The nurse asked the patient if she could drive home by herself and is she not going to be able to feel the pedals in the car. The nurse asked her to have someone to pick her up. This patient was in the 30 minute observation area caller thought because of something in the past, being allergic to, but not to any kind of vaccine. They just take extra precaution. Usually people were in there if they have like an allergy even to like antibiotics or sulfa drugs, things that weren't even included in the ingredient list for Pfizer but just to be extra cautious they put them in the 30 minute observation area. If they start to develop any symptoms they ask them if they could please stay an additional 15 minutes. If symptoms persist or get worse then they keep them longer. Onset date of the reported numbness and tingling in arm was the date she was administered first dose of Pfizer Covid-19 Vaccination, unknown other than approximately 21 days ago. She was in the 30 minute observation and the nurse wanted to say within probably the first 15 minutes she started having symptoms of the numbness and tingling. It was like when you sleep on your arm and it kind of falls asleep, that's how patient described it. The duration of the events lasted the first time, by the next morning, it had resolved. She woke up and she was fine. She was vaccinated probably early to mid-afternoon. The clinic only does vaccines until probably 4:30pm. After the second dose she received today, 16Apr2021 they kept the patient for about an hour. She was still in there when the nurse came out to make this call. The nurse has been checking in on her intermittently and they have 3 nurses in the observation area so they're aware of what's going on with her to keep an extra eye on her  in case she has any difficulty breathing, make sure she doesn't look like she's going to fall out of the chair. They were extra vigilant on observing her. Patient was still having the numbness and tingling, in the legs clarified she has been having numbness and tingling in all of the extremities. In the arms, it wasn't constant. It would come and go and radiated back and forth. Must be something was stimulating in the brain. The events were considered as serious - medically significant. The outcome of the events was recovered on an unspecified date.    Information about lot/batch number has been requested.; Sender's Comments: Based on the information currently available, a possible contributory role of the suspect drug in the reported serious events cannot be completely ruled out given the known suspect drug profile and/or implied temporal association. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including