lupus flare up; lupus flare up; being tired and stuff/fatigue; This is a spontaneous report from a contactable consumer (patient). A 73-year-old female patient received dose 2 of BNT162B2 (Pfizer-BIONTECH COVID-19 Vaccine), via an unspecified route of administration, administered in the left shoulder on 01Mar2021 at 10:15 (at 73-years-old [also reported as 74-yeasr-old]; Batch/Lot number was not reported) single, for COVID-19 immunization. Medical history included autoimmune deficient (had this for a long time), diabetes/diabetic from 1991 and ongoing (additional Information for Other Conditions: Type 2), ongoing psoriasis (had it for years), kidney disease, and lupus. The patient's concomitant medications were not reported. The patient did not have prior vaccinations (within 4 weeks) to the first administration date of the suspect vaccine. The only thing she ever had was a flu vaccine (had that for years and never had a reaction. The patient received the first dose of BNT162B2 on 08Feb2021 (Lot number: EM9809) between 09:00 - 10:00, in the left shoulder. The patient developed a rash three weeks after receiving her secnd dose of the Pfizer-BioNTech COVID-19 Vaccine. She stated that her rash was biopsied by a dermatologist and was diagnosed with lupus flare up on 08Jun2021. She has not been diagnosed with this ever since. She didn't know she had it because she never got a flare-up but she knew she was autoimmune deficient. According to her, nobody cared that she had autoimmune deficiency in the place where she got her vaccination. The doctor told her to get the vaccine so she can go back to work even though the doctor knew she had autoimmune deficiency, kidney disease, and diabetes. Her doctor was now not sure if she can get the booster shot. The patient asked why Pfizer did not include autoimmune deficient people in the clinical trials and yet there are many people with autoimmune deficiency in the world. Stated this was why people don't trust to get shots because nobody can tell them any information about these vaccines. Said that Pfizer can't help her and that they did it wrong, they should have known this information before they went out and vaccinated all these people. According to her, she was just a big thing to make a lot of money and stuff and they should have known this information before they went out and vaccinated all these people. The patient had gone through the CDC and a private physician. Nobody knew nothing so she went straight to the source. She got two vaccines from Pfizer. Other than the normal being tired and stuff, she was doing ok. Three weeks to the day after her second vaccine, she woke up with a rash on her arms and hands, which was in Mar2021. She had the final vaccine in Mar2021. The physician told her it was probably due to a lotion she was using and to just quit using that lotion. The rash went until May2021 and she still had it. She went to a dermatologist, who took a biopsy. The dermatologist thought that maybe it was in the psoriasis family. The biopsy came back as lupus and that she was in a bad flare up. According to her, she never had a flare up in her life, nor did she ever know she had lupus. Nothing had changed with her activities or medications. She did not add new medications. Stated that she "Can take it back to the vaccine and waking up three weeks after the vaccine". She was not saying the vaccine gave her lupus, she just thinks it gave her a flare-up. Fortunately, she knows now she that she has lupus. She still had the rash and looked like a leopard. It was not going away and she was very concerned. The patient waited since Mar2021 with the rash. She was waiting to see a rheumatologist to see how she would treat the lupus. She had no idea she had lupus. The dermatologist said she has had Lupus for a long time. The patient stated that she didn't have it with the first dose and the events started a day or two after the second vaccine. It was really hard to know because she didn't have fatigue with the first dose. She didn't even know if she had a vaccine with the first dose. Didn't know if the fatigue was because the vaccine set something autoimmune off. Initially stated that the rash on her arms and hands began three weeks after second dose. She then, stated that two weeks after, she woke up with the rash. Then clarified that the rash began at the beginning of the third week after the second dose. She still had the rash. Her doctor told her to get the vaccine. She was quarantining for a whole year until the vaccine came out. She couldn't go back to work until she got the vaccines. There was nothing out there about autoimmune deficiency and taking the shot. The doctor didn't have information on it, she just took it. The biopsy was taken on right arm from one of the lesions. Stated there was a lot of bad stuff put out on the internet and news about Pfizer and Moderna  and it was confusing to people. Thought that after she heard it, was she going to die down the road She can't get any of her family or children to get the vaccine because of the stuff they have heard. The patient also stated that no one in her family has lupus. Outcome of the event "lupus flare up" was not recovered, while for 'fatigue' was unknown.  Information regarding the batch/lot number has been requested.