I had hives in multiple places.; I has some mild itching on my hands and feet.; I received a Pfizer second booster (Clarified as Covid19 vaccine) on Thursday evening at 6 pm eastern time; I received a Pfizer second booster (Clarified as Covid19 vaccine) on Thursday evening at 6 pm; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 52-year-old female patient received BNT162b2 (BNT162B2), on 02Jun2022 at 18:00 as dose 4 (booster), single (Lot number: FM9992) at the age of 52 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "I had a root canal (further clarifications unknown) on the Tuesday", start date: 31May2022 (unspecified if ongoing), notes: This morning, I finished Augmentin antibiotic. I had a root canal on the Tuesday, 31May.; "I had a root canal (further clarifications unknown) on the Tuesday" (unspecified if ongoing). Concomitant medication(s) included: AUGMENTIN [AMOXICILLIN;CLAVULANATE POTASSIUM] taken for endodontic procedure, stop date: 06Jun2022. Vaccination history included: BNT162b2 (Prior Vaccination: Consumer stated, "My previous vaccination, my first booster was done on 21Jan2022. I have the LOT# if you need that, FK9729.), administration date: 21Jan2022, when the patient was 52-year-old, for Covid-19 immunization; Covid-19 vaccine (Primary immunisation complete, 1st and 2nd dose, Manufacturer: unknown), for Covid-19 immunization. The following information was reported: OFF LABEL USE (non-serious), IMMUNISATION (non-serious) all with onset 02Jun2022 at 18:00, outcome "unknown" and all described as "I received a Pfizer second booster (Clarified as Covid19 vaccine) on Thursday evening at 6 pm"; PRURITUS (non-serious) with onset 03Jun2022, outcome "recovering", described as "I has some mild itching on my hands and feet."; URTICARIA (non-serious) with onset 04Jun2022 at 18:00, outcome "unknown", described as "I had hives in multiple places.". The events "i has some mild itching on my hands and feet." and "i had hives in multiple places." required physician office visit. Therapeutic measures were taken as a result of pruritus, urticaria.  Additional information : The paient stated, "I received a Pfizer second booster (Clarified as Covid19 vaccine) on Thursday evening at 6 pm. On Friday morning, I has some mild itching on my hands and feet, Claritin (intent treatment) took care of it but then on Saturday morning I woke up and I had hives in multiple places. I had to contact a doctor who perfectly called in and prescribed me a steroid (Treatment) and others medication (Intent: Treatment) to tried to change the itching and the hives and I thought I should report this to you." The consumer stated, "I don't have the expiration date. That's all I have and No, the only other information I have that is the professional clinic site. I don't have any other information on it." The patient not had clinic site number For treatment patient stated, "They gave me Prednisone for the steroid". She was taking Zyrtec. They also had her taking Pepcid and using topical Cortizone 10." For other medications: Patient finished Augmentin antibiotic this morning. She had a root canal (further clarifications unknown) on the Tuesday, 31May. The patient stated regarding her previous vaccination, her first booster was done on 21Jan2022. She had the Lot no. FK9729. The patient still had some itchiness on her hand's today and yes, it was improved with the steroids.  No statement needed. FU will be conducted.