face became red/arms became red all over/legs turned red up to below their knees/all their body joints including, fingers, ankles and elbows were dark red/face and ears turned red, starting in their forehead/arms turned red again, reaching the elbows; face became swollen; between the index fingers and their thumbs, became swollen; between the index fingers and their thumbs hurts/hurts to separate those fingers/buttocks and the back of their legs hurt; between the index fingers and their thumbsthey have a tingling sensation/right hand has the tingling sensation again; between the index fingers and their thumbs feels like cramping; area between those fingers is dark, with red parts and bluish parts/the index finger is dark in the knuckle section/buttocks,  had hot dark areas/soles of their feet were colored from pink to purple/bottom and top eyelids pur/cheeks and nose got purp; itchiness in their belly/itchiness in  their knees; knees were dark and swollen; the back of their head and neck felt weird like something was squeezing their head; face turned hot; bottom and top eyelids swelled up; felt like having sinusitis; buttocks and the back of their legs, till the knees, hurt and were hot; Head felt tight, feeling compression in their head/then the back of their head and neck felt weird like something was squeezing their head; knees, hurt; body aches; tired; This spontaneous case was reported by a consumer and describes the occurrence of ERYTHEMA (face became red/arms became red all over/legs turned red up to below their knees/all their body joints including, fingers, ankles and elbows were dark red/face and ears turned red, starting in their forehead/arms turned red again, reaching the elbows), SWELLING FACE (face became swollen), PERIPHERAL SWELLING (between the index fingers and their thumbs, became swollen), PAIN IN EXTREMITY (between the index fingers and their thumbs hurts/hurts to separate those fingers/buttocks and the back of their legs hurt) and PARAESTHESIA (between the index fingers and their thumbsthey have a tingling sensation/right hand has the tingling sensation again) in a 35-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 050F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Concomitant products included vitamin C, ZINC, omega 3 and Vitamin D3&K2 for an unknown indication.    On 26-Sep-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced ERYTHEMA (face became red/arms became red all over/legs turned red up to below their knees/all their body joints including, fingers, ankles and elbows were dark red/face and ears turned red, starting in their forehead/arms turned red again, reaching the elbows), SWELLING FACE (face became swollen), PERIPHERAL SWELLING (between the index fingers and their thumbs, became swollen), PAIN IN EXTREMITY (between the index fingers and their thumbs hurts/hurts to separate those fingers/buttocks and the back of their legs hurt), PARAESTHESIA (between the index fingers and their thumbsthey have a tingling sensation/right hand has the tingling sensation again), MUSCLE SPASMS (between the index fingers and their thumbs feels like cramping), SKIN DISCOLOURATION (area between those fingers is dark, with red parts and bluish parts/the index finger is dark in the knuckle section/buttocks,  had hot dark areas/soles of their feet were colored from pink to purple/bottom and top eyelids pur/cheeks and nose got purp), PRURITUS (itchiness in their belly/itchiness in  their knees), JOINT SWELLING (knees were dark and swollen), MUSCULOSKELETAL DISCOMFORT (the back of their head and neck felt weird like something was squeezing their head), FEELING HOT (face turned hot), SWELLING OF EYELID (bottom and top eyelids swelled up), FEELING ABNORMAL (felt like having sinusitis), MUSCULOSKELETAL PAIN (buttocks and the back of their legs, till the knees, hurt and were hot), HEAD DISCOMFORT (Head felt tight, feeling compression in their head/then the back of their head and neck felt weird like something was squeezing their head), ARTHRALGIA (knees, hurt), MYALGIA (body aches) and FATIGUE (tired). At the time of the report, ERYTHEMA (face became red/arms became red all over/legs turned red up to below their knees/all their body joints including, fingers, ankles and elbows were dark red/face and ears turned red, starting in their forehead/arms turned red again, reaching the elbows), SWELLING FACE (face became swollen), PERIPHERAL SWELLING (between the index fingers and their thumbs, became swollen), PAIN IN EXTREMITY (between the index fingers and their thumbs hurts/hurts to separate those fingers/buttocks and the back of their legs hurt), PARAESTHESIA (between the index fingers and their thumbsthey have a tingling sensation/right hand has the tingling sensation again), MUSCLE SPASMS (between the index fingers and their thumbs feels like cramping), SKIN DISCOLOURATION (area between those fingers is dark, with red parts and bluish parts/the index finger is dark in the knuckle section/buttocks,  had hot dark areas/soles of their feet were colored from pink to purple/bottom and top eyelids pur/cheeks and nose got purp), PRURITUS (itchiness in their belly/itchiness in  their knees), JOINT SWELLING (knees were dark and swollen), MUSCULOSKELETAL DISCOMFORT (the back of their head and neck felt weird like something was squeezing their head), FEELING HOT (face turned hot), SWELLING OF EYELID (bottom and top eyelids swelled up), FEELING ABNORMAL (felt like having sinusitis), MUSCULOSKELETAL PAIN (buttocks and the back of their legs, till the knees, hurt and were hot), HEAD DISCOMFORT (Head felt tight, feeling compression in their head/then the back of their head and neck felt weird like something was squeezing their head), ARTHRALGIA (knees, hurt), MYALGIA (body aches) and FATIGUE (tired) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   NO treatment medication was reported