WORSENING AND PROGRESSED ANEMIA; INCREASED BP; ERRATIC HEART BEAT; WORSENING AND PROGRESSED IRREGULAR APPETITES; WORSENING AND PROGRESSED INSOMNIA; WORSENING AND PROGRESSED NIGHT SWEATS; CAN HARDLY WALK WITHOUT EXERTING EFFORT; WORSENING AND PROGRESSED CHEST TIGHTNESS; WORSENING AND PROGRESSED BACK PAIN; WORSENING AND PROGRESSED BELLY/STOMACH SWOLLEN; IRRITABLE; WORSENING AND PROGRESSED LEFT LEG FEELS BRUISED; WORSENING AND PROGRESSED BOWEL MOVEMENT; WORSENING AND PROGRESSED LOW URINE; CAN'T BREATHE; BRUISING FEELING AT INJECTION SITE; SWOLLEN AREA BETWEEN LEFT-SIDE OF NECK AND LEFT COLLAR BONE; This spontaneous report received from a patient concerned a 75 year old female. The patient's height, and weight were not reported. The patient's concurrent conditions included cigarette smoker, non-alcohol user, anemia, high blood pressure, erratic heart beat, irregular appetite, insomnia, night sweats, can hardly walk without exerting effort, chest tightness, shortness of breathe, back hurts bad, belly/stomach swollen, irritable, left leg feels bruised, low urine, and bowel movement, and other pre-existing medical conditions included the patient had no known drug or non-drug allergies. The patient did not have drug abuse or illicit drug usage. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: Unknown) dose was not reported, administered on 28-MAR-2021 11:10 for prophylactic vaccination. The batch number was not reported and has been requested. Concomitant medications included acetylsalicylic acid for drug used for unknown indication, ascorbic acid/ergocalciferol/folic acid/nicotinamide/panthenol/retinol/riboflavin/thiamine hydrochloride for drug used for unknown indication, clopidogrel bisulfate for drug used for unknown indication, lisinopril for drug used for unknown indication, and metoprolol for drug used for unknown indication. On 01-APR-2021, the subject experienced bruising feeling at injection site. On 01-APR-2021, the subject experienced swollen area between left-side of neck and left collar bone. On JUN-2021, the subject experienced can't breathe. On 01-JUN-2021, the subject experienced worsening and progressed anemia. On 01-JUN-2021, the subject experienced increased bp. On 01-JUN-2021, the subject experienced erratic heart beat. On 01-JUN-2021, the subject experienced worsening and progressed irregular appetites. On 01-JUN-2021, the subject experienced worsening and progressed insomnia. On 01-JUN-2021, the subject experienced worsening and progressed night sweats. On 01-JUN-2021, the subject experienced can hardly walk without exerting effort. On 01-JUN-2021, the subject experienced worsening and progressed chest tightness. On 01-JUN-2021, the subject experienced worsening and progressed back pain. On 01-JUN-2021, the subject experienced worsening and progressed belly/stomach swollen. On 01-JUN-2021, the subject experienced irritable. On 01-JUN-2021, the subject experienced worsening and progressed left leg feels bruised. On 01-JUN-2021, the subject experienced worsening and progressed bowel movement. On 01-JUN-2021, the subject experienced worsening and progressed low urine. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from bruising feeling at injection site, swollen area between left-side of neck and left collar bone, worsening and progressed anemia, increased bp, erratic heart beat, worsening and progressed irregular appetites, worsening and progressed insomnia, worsening and progressed night sweats, can hardly walk without exerting effort, worsening and progressed chest tightness, worsening and progressed back pain, worsening and progressed belly/stomach swollen, irritable, worsening and progressed left leg feels bruised, worsening and progressed bowel movement, worsening and progressed low urine, and can't breathe. This report was non-serious.