first and second dose, shingles/suspected vaccination failure; shingles; feels like someone has their fingers around neck, spasms/ Cramps; excruciating pain in left side of neck; left ear numb; Left shoulder pain; red rash from chin to shoulder; feels like someone has their fingers around neck, spasms/ Cramps; first dose in 2020, July 2021 received dose 2; left side of face feels strange, like someone was touching, left eye strange; shortly after that his Left eye felt strange; This case was reported by a consumer via call center representative and described the occurrence of vaccination failure in a 82-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   In July 2021, the patient received the 2nd dose of Shingrix. In 2020, the patient received the 1st dose of Shingrix. On 1st August 2021, less than a month after receiving Shingrix and less than 2 years after receiving Shingrix, the patient experienced paresthesia and abnormal sensation in eye. On an unknown date, the patient experienced vaccination failure (serious criteria GSK medically significant), shingles, feeling abnormal, neck pain, ear numbness, shoulder pain, red rash, cramp and drug dose administration interval too long. On an unknown date, the outcome of the vaccination failure, cramp and drug dose administration interval too long were unknown and the outcome of the shingles, paresthesia, abnormal sensation in eye, feeling abnormal, neck pain, ear numbness, shoulder pain and red rash were recovering/resolving.   It was unknown if the reporter considered the vaccination failure, shingles, paresthesia, abnormal sensation in eye, feeling abnormal, neck pain, ear numbness, shoulder pain, red rash and cramp to be related to Shingrix and Shingrix.     Additional Information: GSK Receipt Date: 04-Aug-2022 Reporters comments: The patient reports he received his first dose of Shingrix in 2020. (doesn't remember the exact date) In July 2021, the patient received dose 2 (after the 6 month mark) He states he ended up in the emergency room 5 times in the past year. He states on 1st August 21  reports his left side of face feels strange, like someone was touching him, but they weren't. then shortly after that his left eye felt strange. He went to eye doctor and no vision changes noted. A month later he had cramps and excruciating pain in left side of neck, left ear numb. Left shoulder pain scale was 3 and went up to 4 when touched. Finally, 2 months ago he had a red rash from under left side of chin to left shoulder. He was diagnosed with shingles. He states it feels like someone has their fingers around neck, maybe spasms. He reports he had visited to multiple specialist, had CT scans, MRI and has paid out of pocket. He states the symptoms are now subsiding from all of this. In June 2022, less than a year after receiving 2nd dose of Shingrix, the patient experienced red rash. In June 2022, less than a month after receiving 2nd dose of Shingrix, the patient experienced vaccination failure and shingles. On an unknown date, less than 2 years after receiving 1st dose of Shingrix, the patient experienced vaccination failure, shingles, paresthesia, abnormal sensation in eye, neck pain, ear numbness and shoulder pain. The reporter did not consent to follow-up. Additional Supportive Information: This case was considered as suspected vaccination failure as details regarding, laboratory test confirming shingles were unknown at the time of reporting. The patient received the received his first dose of Shingrix in 2020 and the 2nd dose in July 2021, which led to lengthening of the schedule, hence the event was captured as drug dose administration interval too long and linked with 2nd dose.