left breast tenderness; first dose of Pfizer vaccine on 08Oct2021/ second dose on 01Dec2021; heart constrictions; cannot sleep at night; The patient had heart issue and felt pain in chest; Heart issue; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 55-year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 01Dec2021 (Lot number: 301358M) at the age of 55 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "cholesterol was high" (unspecified if ongoing), notes: she was completely healthy before the shot but her cholesterol was high; "pre-diabetic" (unspecified if ongoing), notes: she was pre-diabetic. The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, Time: 12:00 pm, Anatomical location: Left arm, Lot number: EVV0185), administration date: 08Oct2021, for COVID-19 Immunization, reaction(s): "left breast tenderness/tenderness in her breast". The following information was reported: ANGINA PECTORIS (medically significant) with onset Dec2021, outcome "not recovered", described as "The patient had heart issue and felt pain in chest"; CARDIAC DISORDER (non-serious) with onset Dec2021, outcome "not recovered", described as "Heart issue"; BREAST TENDERNESS (non-serious) with onset 01Dec2021, outcome "not recovered", described as "left breast tenderness"; CHEST DISCOMFORT (non-serious) with onset Dec2021, outcome "not recovered", described as "heart constrictions"; INSOMNIA (non-serious) with onset Dec2021, outcome "not recovered", described as "cannot sleep at night"; INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (non-serious) with onset 01Dec2021, outcome "unknown", described as "first dose of Pfizer vaccine on 08Oct2021/ second dose on 01Dec2021". The events "the patient had heart issue and felt pain in chest", "heart issue", "left breast tenderness", "heart constrictions" and "cannot sleep at night" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: blood pressure measurement: (Dec2021) normal; electrocardiogram: (Dec2021) everything was fine. The facility type vaccine was hospital. The report was not related to a study or programme. The patient reported that she received the second dose on 01Dec2021 where she experienced chest pain. The patient clarified that after receiving the 1st dose everything was fine, but after receiving the second dose she had left breast tenderness almost immediately after receiving the second dose and had chest pain almost a week after receiving the second dose. The patient stated she went to see her doctor a week after where they did an electrocardiogram (EKG) where everything was fine and took her blood pressure was normal but she still had chest pain. The patient stated that she had a doctor appointment at 1:30 and did not know if she needed to go on a beta blocker. The patient stated her doctor recommended she saw a cardiologist but everyone was booked through Jan2022 and she could only start to book an appointment as of 18Jan2022. The patient stated she had a visual appointment with a Doctor today (as reported) but it was not a cardiologist. The patient reported that she thought that pain would go away and it has not and it had been three weeks. The patient reported that the other women only had breast tenderness and she had heart constrictions and could not sleep at night. The patient had breast tenderness one week after 1st shot of vaccine. Two month later, the patient still had tenderness that was uncomfortable, many others who the patient talked had this pain. More importantly, the patient had heart issue for 4 weeks after the 2nd dose. The patient felt pain in chest that was severe. There were nights when the patient felt like she was going to die in her sleep. The paitent reported she had to see cardiologist.  No follow-up attempts are needed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101877385 Same patient, different dose and event;US-PFIZER INC-202101878670 Same reporter, different patients and event;US-PFIZER INC-202101878634 Same reporter, different patients and event;US-PFIZER INC-202101878669 Same reporter, different patients and event;US-PFIZER INC-202200292853 Same reporter, different patients and event;US-PFIZER INC-202200292873 Same reporter, different patients and event