her blood level was 3.2 March 3rd, she was in the ICU; This is a spontaneous report from a contactable consumer (Patient's mother). A 38-year-old female patient received first dose of BNT162B2 (BNT162B2) via an unspecified route of administration, administered in Arm Right on 26Feb2021 (Batch/Lot Number: EN6205; Expiration Date: 30Jun2021) as 1ST DOSE, SINGLE for covid-19 immunization. Medical history included sickle cell disease from an unknown date, bone marrow transplant from 1993, stroke from an unknown date (when she was two and a half years old), paralysis (paralyzed on her left side by a stroke when she was two and a half years old), seizure and blood transfusion both from unknown dates. Concomitant medications included lamotrigine (LAMICTAL ODT) and pregabalin (LYRICA) both taken for seizure, start and stop dates were not reported. The patient experienced her blood level was 3.2 march 3rd, she was in the icu on 03Mar2021 and was hospitalized from 03Mar2021 to 13Mar2021.  She says her daughter was admitted to the hospital during February and was discharged February 19th, and that day she got a blood transfusion, they gave her 3 units of blood for a sickle cell complication. Reporter says her daughter got the first dose of the Pfizer COVID-19 vaccine February 26th, and was supposed to get her second dose in March, but she she went back to the hospital because she had a bad crisis, her blood level was 3.2 March 3rd, she was in the ICU. She wants recommendation about getting her 2nd dose. Reporter stated, We don't feel comfortable that she doesn't have the 2nd dose. We just want to have the 2nd dose and be safe. She received her Pfizer covid vaccine on 26Feb2021 expiry 30Jun2021. Patient had a bone borrow transplant at age of 10; she's received so many blood transfusions, she has so many antibodies. She had a bone marrow transplant in 1993 when she was 10 years old, that was 28 years ago. Patient's age clarified to 38, and caller says her daughter is not a baby, they would like to know what should they do, should they go ahead and have her get the second dose of the Pfizer COVID-19 vaccine. Reporter says her daughter is paralyzed on one side from a stroke she had when she was a kid. Clarifies that her daughter had been discharged from the hospital before she got the vaccine, she was discharged February 19th, then got her first dose February 26th. She says on March 3rd her daughter was back in the hospital in the ICU for four days, then was in the hospital from March 3rd to the 13th. She says she received 3 more blood transfusions or 3 units of blood. She says because of that, she has not done her second dose. Reporter says her daughter takes Lamictal on a regular basis, and Lyrica, she has been taking it more than 20 years for seizures, but her seizures stopped and went away completely, so the medication is controlling it, it is not often she has them, she takes those two meds for seizures. She says something about her daughter taking Psyllium seeds, no further details provided about this. She says her daughter gets the flu shot every year and does ok. No further details provided about unspecified flu shots. Reporter added her daughter has sickle cell, sometimes she sees her doctor every 3 months and when her blood level is low she gets transfusions, and when it doesn't get caught that it is getting low she ends up in the hospital and they do transfusions anyway. She says in the beginning she did a bone marrow transplant when she was 10 years old, and then later her left side was paralyzed when she was two and a half. She says her daughter lives a very normal life until her blood is low, which happens a lot of times when she has her period, then that one goes out, and then she goes back to herself, with her sickle cell. The patient underwent lab tests and procedures which included blood count: 3.2 on 03Mar2021. Outcome of the event was unknown.   Follow up attempts are completed. No further information is expected.