huge blood clot covering both lungs against her heart; had pain on her side and belching; fibroids (colon); feet swollen tremendously; ankle swollen tremendously; Constipation; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 76-year-old female patient received BNT162b2 (BNT162B2), on 30Nov2021 as dose 3 (booster), single (Lot number: FH8030) at the age of 76 years, in left arm for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: BNT162b2 (Second Covid vaccine was on 03Mar2021 with a lot number of EN6203), administration date: 03Mar2021, when the patient was 75-year-old, for COVID-19 immunization; BNT162b2 (Dose 1), administration date: 15Feb2021, when the patient was 75-year-old, for COVID-19 immunization. The following information was reported: CONSTIPATION (non-serious) with onset Dec2021, outcome "recovered" (Dec2021); JOINT SWELLING (non-serious) with onset Dec2021, outcome "recovered" (Dec2021), described as "ankle swollen tremendously"; PERIPHERAL SWELLING (non-serious) with onset Dec2021, outcome "recovered" (Dec2021), described as "feet swollen tremendously"; GASTRIC POLYPS (medically significant) with onset Dec2021, outcome "recovered" (Dec2021), described as "fibroids (colon)"; PULMONARY EMBOLISM (hospitalization, medically significant, life threatening) with onset 20Jan2022, outcome "recovered" (20Jan2022), described as "huge blood clot covering both lungs against her heart"; EPIGASTRIC DISCOMFORT (non-serious), outcome "unknown", described as "had pain on her side and belching". Caller stated that she had gotten the booster on 30Nov2021. About 1.5 weeks after that her feet and ankles swollen tremendously. Called her cardiologist and was told to take a diuretic once a day for week. Swelling went down. Did not call her cardiologist and he did not call her. Two weeks after that she had constipation. Had herself checked. Had fibroids which were removed and were not cancerous. Flew to (state withheld) 1.5 weeks later and had pain on her side and belching so she took Gas-X but it did not help. Went to a walk in clinic and was tested for Covid and there was none. Was tested for pneumonia and there was none. Tested for Covid and pneumonia on 20Jan2022. Had a CAT scan on 20Jan2022 and there was a huge blood clot on her lungs. Was sent to the hospital by ambulance immediately. Called her family because they were unsure if she would make it. Used on 20Jan2022 which was two catheters from the groin to the blood clot which broke it up. Was put on blood thinners and today is on still on blood thinners. Unsure if this is related to but thinks so. Is for the first booster after the first two vaccines. Later clarified that it was for the Covid vaccine. Wanted to know do they now tell you how much the dosage is since the question was asked.  Later clarified fibroids were on her colon. Later clarified that the huge blood clot was covering both lungs against her heart. All vaccines were Pfizer. Feet and ankles swollen tremendously: Resolved week after taking diuretic. Constipation: Resolved at the end of Dec2021. Took over the counter enemas and things to relieve gas and whatever doctor suggested over the counter. Fibroids (colon). Had six taken out from her colon that were tested and were negative in Dec2021. The events "huge blood clot covering both lungs against her heart", "fibroids (colon)", "feet swollen tremendously", "ankle swollen tremendously", "constipation" and "had pain on her side and belching" required physician office visit. The patient underwent the following laboratory tests and procedures: Computerized tomogram: (20Jan2022) there was a huge blood clot on her lungs; Pneumonia: (20Jan2022) there was none; SARS-CoV-2 test: (20Jan2022) there was none; Uterine leiomyoma: (Dec2021) Negative, notes: Had six taken out from her colon that were tested and were negative in Dec2021. Therapeutic measures were taken as a result of pulmonary embolism, gastric polyps, peripheral swelling, joint swelling, constipation, epigastric discomfort. Follow-up (26Sep2022): Follow-up attempts are completed. No further information is expected.