Provider suggested the patient not receive the second dose; Left hand being blown up and inflamed; Very painful to move the hands; Patient almost wasn't able to get their wedding ring off/right hand became swollen as well/hands very swollen/both hands were extremely swollen and kept swelling; hands looked like baseball mitts/ both hands were extremely swollen and kept swelling; Fever; Body aches; Feeling tired/tired; Not feeling great; Arm pain/arm pain came back; This spontaneous case was reported by a consumer and describes the occurrence of MALAISE (Not feeling great), PAIN IN EXTREMITY (Arm pain/arm pain came back), VACCINATION SITE INFLAMMATION (Left hand being blown up and inflamed), VACCINATION SITE MOVEMENT IMPAIRMENT (Very painful to move the hands) and PERIPHERAL SWELLING (Patient almost wasn't able to get their wedding ring off/right hand became swollen as well/hands very swollen/both hands were extremely swollen and kept swelling) in a 68-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 030L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included THYROID (ARMOUR THYROID) for an unknown indication.    On 16-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 16-Feb-2021, the patient experienced MALAISE (Not feeling great), PAIN IN EXTREMITY (Arm pain/arm pain came back), PYREXIA (Fever), MYALGIA (Body aches) and FATIGUE (Feeling tired/tired). On 25-Feb-2021, the patient experienced VACCINATION SITE INFLAMMATION (Left hand being blown up and inflamed), VACCINATION SITE MOVEMENT IMPAIRMENT (Very painful to move the hands), PERIPHERAL SWELLING (Patient almost wasn't able to get their wedding ring off/right hand became swollen as well/hands very swollen/both hands were extremely swollen and kept swelling) and PERIPHERAL SWELLING (hands looked like baseball mitts/ both hands were extremely swollen and kept swelling). On an unknown date, the patient experienced OFF LABEL USE (Provider suggested the patient not receive the second dose). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) at a dose of 1 dosage form. On 17-Feb-2021, PYREXIA (Fever) had resolved. On 20-Feb-2021, MALAISE (Not feeling great), MYALGIA (Body aches) and FATIGUE (Feeling tired/tired) had resolved. On 04-Mar-2021, VACCINATION SITE INFLAMMATION (Left hand being blown up and inflamed), VACCINATION SITE MOVEMENT IMPAIRMENT (Very painful to move the hands), PERIPHERAL SWELLING (Patient almost wasn't able to get their wedding ring off/right hand became swollen as well/hands very swollen/both hands were extremely swollen and kept swelling) and PERIPHERAL SWELLING (hands looked like baseball mitts/ both hands were extremely swollen and kept swelling) had resolved. At the time of the report, PAIN IN EXTREMITY (Arm pain/arm pain came back) and OFF LABEL USE (Provider suggested the patient not receive the second dose) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Most recent FOLLOW-UP information incorporated above includes: On 06-Aug-2021: Non significant follow-up received on 06-Aug-2021 On 03-Sep-2021: Report contains no new information.