Bacterial infection; Shingles; she broke out in a rash; This is a spontaneous report from a contactable consumer (patient). An 80-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE), dose 1 via an unspecified route of administration, administered in Arm Left on 20Jan2021 12:00 (Batch/Lot Number: EL8982) as SINGLE DOSE for COVID-19 immunisation; adalimumab (HUMIRA), via an unspecified route of administration from Nov2020 (Batch/Lot number was not reported) and ongoing, at 40mg (0.4mi) self injection every two weeks/She gets it twice a month) for psoriatic arthritis. Medical history included hypertension, diabetes type II, low thyroid, high cholesterol, chickenpox and she had part of her thyroid removed and psoriatic arthritis from an unknown date and unknown if ongoing. Concomitant medications included pravastatin taken for blood cholesterol increased from an unspecified start date and ongoing; ezetimibe (ZETIA) taken for blood cholesterol from an unspecified start date and ongoing; dulaglutide (TRULICITY) taken for type 2 diabetes mellitus from an unspecified start date and ongoing; azilsartan kamedoxomil (EDARBI) taken for blood pressure from an unspecified start date and ongoing; doxazosin taken for blood pressure from an unspecified start date and ongoing; l-thyroxine [levothyroxine] (L-THYROXINE) taken for low thyroid from an unspecified start date and ongoing; metformin hydrochloride, sitagliptin phosphate monohydrate (JANUMET XR) taken for type 2 diabetes mellitus, start and stop date were not reported. The patient previously took enbrel for psoriasis and experienced psoriatic arthropathy, enbrel for psoriasis and experienced psoriasis, and a flu shot. The patient was an 80 years old with compromised health because she takes a biological medication. On 20Jan2021, she had her first dose of COVID19 vaccine. No sore arm and everything was fine. On 27Jan2021, she broke out in a rash on her right lower arm between the elbow and wrist. She thought it was an allergy. When she thought it was more than that she went to the doctor. Diagnosed on 29Jan2021 with shingles. She was immediately put on the protocol of Gabapentin and Valtrex, the antiviral.  It got worse. She gave it one more day and yesterday she went to the doctor. She has a bacterial infection on top of shingles. She is on the second day of antibiotic. Her question is her second Pfizer COVID19 shot is scheduled for 10Feb2021. Should she take it? Is it safe to do that? She also wanted to report it so it would be part of the database in case other people break out. She wasn't allowed to take the Shingles vaccines because the doctors did not want her to because of her compromised system. She has not had Shingles vaccine, but she did have chickenpox when she was younger. The rash is raging and like a flesh eating monster. It is bacterial and shingles. The patient was on gabapentin strength: 100mg. She took one a day for three days and now is up to three a day. The patient's glasses are giving her trouble. She is nearly useless with all this going on. She had to get her husband to read the pharmacy vial for her. The patient was on Valtrex taking generic called Valacyclovir. It is 1 gram tablet. Taking it three times a day. NDC, lot, and expiry: product in a pharmacy vial. The antibiotic she was put on was Doxycycline Hyclate 100mg twice a day.  NDC, lot, and expiry: product in pharmacy vial. The biological medication she takes is Humira. She gets it twice a month. It is given by self injection with 29 gauge. She has been on a biological for 10 years. Before Humira she was on Enbrel. When she was put on Enbrel she had psoriasis and psoriatic arthritis. Enbrel took care of psoriasis. She still has psoriatic arthritis. They are gong to switch her to a new medication. She thinks it is called Talk, but she is not sure. She is waiting on the insurance to approve it. She has not started that yet. She thinks Gabapentin is affecting her vision. On the COVID19 vaccination card the information that said Pfizer, lot number, and date were on a little sticker that was taped on the card. Caller had to get her husband to read it to her. For the healthcare professional it was initialed. The patient doesn't want to die of Shingles either. These shingles are bad. She took the COVID vaccine because her health is compromised. She has hypertension, diabetes type II, and Psoriatic Arthritis. They qualified her for conditions along with her age. She thinks she stays positive because she doesn't dwell on this all the time. She just does it. She hasn't taken Humira since the diagnosis of Shingles because she has always been told to stop the biologic if she has an infection. She has been holding the Humira. It was due this week, but she did not take it. The outcome of the event rash was not recovered. The outcome of the rest of the events was unknown. The action taken of adalimumab for the events was temporarily withdrawn on unspecified date.  Follow-up attempts are completed. No further information is expected.