Vaccine made it worse/irritation in my stomach, acid reflux; Nausea/she felt like she had to throw up; Headache; She experienced pain at the injection site, swelling; She experienced pain at the injection site, swelling; acid reflux; Irritable bowel syndrome; Bloating; This is a spontaneous report from a contactable consumer,  A 65-years-old female patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Lot Number: EL8982), via an unspecified route of administration, administered in left arm on 22Jan2021 (at the age of 65-years-old) as a single dose for covid-19 immunization. Medical history included depression, osteoarthritis, constipation, gastrooesophageal reflux disease, arthralgia (She was already experiencing joint pain prior to the vaccine). Concomitant medication(s) included linaclotide taken for constipation; famotidine taken for gastrooesophageal reflux disease. She clarifies that her First Dose was on 22Jan2021, she experienced pain at the injection site, swelling, and it was no problem the swelling went down quick, and the pain went away, she experienced this Friday 22Jan2021, Saturday 23Jan2021 and Sunday 24Jan2021. Her headache actually started right after the injection on Friday 22Jan2021, the headaches are on and off and she experienced her last one Monday or Tuesday. On Monday 25Jan2021 and Tuesday 26Jan2021 she experienced the stomach irritation acid reflux. She clarified that she did not actually throw up, she just felt like she had to throw up, she wasn't feeling well, she had a few headaches, and joint pain. The joint pain was also on and off, how when she will talk to the other person, she will add that the joint pain, she does have osteoarthritis and so she doesn't know if the joint pain is from the vaccine or from osteoarthritis, that why she wants to ask if she can get the cortisone injection, she confirms that she was already experiencing joint pain prior to the vaccine. Height: She has dropped like 2 inches, She was 5 feet 7.5 inches, the bone density scan says she is shorter. She clarifies that she already had acid reflux and is on a medication for that, the vaccine just made it worse, it made her irritation in the stomach worse, it made the acid reflux worse and so the acid reflux medication is not working, now she feels like throwing up, the vaccine made the acid reflux medication stop working. The name of her acid reflux medication- Famotidine, she has no lot or expiry to provide as the product was not physically with her. She had irritable bowl syndrome, but it's not feeling well. It's getting better except the joint pain. The acid reflux was bothering. She felt like my medication wasn't working as well. No breathing problems. Breathing was very good. Some bloating but the medication feels like it's not working. The patient getting an injection of cortisone for knee pain on Tuesday. Any information or should I postpone. When queried investigation she states that she was taking depression medication. The outcome of the headache; vaccine made it worse/irritation in my stomach, acid reflux; nausea/she felt like she had to throw up and she experienced pain at the injection site, swelling was recovered; for bloating was unknown and while that of the irritable bowel syndrome was recovering at the time of report.  Follow-up attempts are completed. No further information is expected.