heart attack on 16Dec2022; 2 blocked arteries; Diffuse B-Cell Lymphoma in Nov2022; Diffuse B-Cell Lymphoma in Nov2022; This is a spontaneous report received from a contactable reporter (Consumer or other non HCP). The reporter is the patient.  A 56-year-old female patient (not pregnant) received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 06Oct2022 as dose 4 (booster), single (Lot number: GJ6742) at the age of 56 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "B-Cell Lymphoma" (unspecified if ongoing); "Never smoked" (unspecified if ongoing). Concomitant medications included: ACCURETIC; TRINTELLIX; ADDERALL. Vaccination history included: BNT162b2 (dose number: 3, lot number: FC3180, in Right arm), administration date: 29Aug2021, when the patient was 55-year-old, for COVID-19 Immunization; BNT162b2 (dose number: 2, lot number: EN6203, in Left leg), administration date: 17Mar2021, when the patient was 54-year-old, for COVID-19 Immunization; BNT162b2 (dose number: 1, lot number: EN6203, in Left leg), administration date: 25Feb2021, when the patient was 54-year-old, for COVID-19 Immunization. The following information was reported: B-CELL LYMPHOMA (hospitalization, medically significant, life threatening), DISEASE RECURRENCE (hospitalization, medically significant, life threatening) all with onset Nov2022, outcome "recovered with sequelae" (Dec2022) and all described as "Diffuse B-Cell Lymphoma in Nov2022"; ARTERIAL OCCLUSIVE DISEASE (hospitalization, medically significant, life threatening) with onset 16Dec2022, outcome "recovered with sequelae" (Dec2022), described as "2 blocked arteries"; MYOCARDIAL INFARCTION (hospitalization, medically significant, life threatening) with onset 16Dec2022, outcome "recovered with sequelae" (Dec2022), described as "heart attack on 16Dec2022". The patient was hospitalized for b-cell lymphoma, disease recurrence, myocardial infarction, arterial occlusive disease (start date: 2022, discharge date: 2022, hospitalization duration: 3 days). The events "diffuse b-cell lymphoma in nov2022", "heart attack on 16dec2022" and "2 blocked arteries" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: SARS-CoV-2 test: (unspecified date) Negative; Scan: (2015) no calcifications were present at that time. Therapeutic measures were taken as a result of b-cell lymphoma, disease recurrence, myocardial infarction, arterial occlusive disease. Clinical course: The patient did not receive other vaccine in four weeks. The patient reported, "Diagnosed with Diffuse B-Cell Lymphoma in Nov2022. Then I had a heart attack on 16Dec2022. No previous history of heart disease. In 2015, had full body scan and no calcifications were present at that time. No problems with cholesterol, never smoked, blood pressure under control. Cardiologist cannot explain why this happened and in such a short time, I had 2 blocked arteries. I had two stents put in." Adverse event start date was on 16Dec2022 (as reported). Adverse event treatment included catheterization and stents, medication. The patient had no COVID prior vaccination and was tested for COVID post vaccination via nasal swab with negative result. The patient had no known allergies.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201393472 same patient/vaccine, different dose/event;US-PFIZER INC-202201393473 same patient/vaccine, different dose/event;