Tooth reinfected between the two doses; Fever and chills; Fever and chills; This is a spontaneous report received from a contactable consumer (Patient).  A 79-year-old female patient of an unspecified age received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; formulation solution for injection; Lot number: ER2613), via an unspecified route of administration on 18Mar2021 (at the age of 78-year-old), as single for Covid-19 immunization. Medical history included thyroid cancer from 1979 to an unknown date, osteoporosis, back surgery, car accident prior to the pandemic, broken wrist and nerve damage, head and neck cancer, stroke, Brain tumor (inactive), vestibular issues, corneal transplants (two), tooth infection/ like slow infection from 2018 to an unknown date; she was visually disabled; her root canal that got infected and her thyroid was removed surgically, both from 2018 to an unknown date. The previously took bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE; formulation solution for injection; Lot number: EN6202), via an unspecified route of administration in Arm left on 25Feb2021 (at the age of 78-year-old), as single for Covid-19 immunization and Shingrex vaccine with horrible reaction. The patient's concomitant medication included levothyroxine (LEVOTHYROXINE) taken for thyroid hormone replacement therapy and zoledronic acid (RECLAST) infusion one time in a year, taken for osteoporosis. On an unspecified date, after the second dose the patient experienced tooth reinfected between the two doses, fever, and chills. She stated that she went to a site where vaccines were being administered by nurses and mentioned that she was diagnosed with cancer there in 1979. When she got the first dose of the vaccine, she had to fill out a health history form, had to talk to a nurse about it, then she got a shot while at the second time around it was different because the nurses leaned in the back window to talk to her and gave her the shot, and she did not have to fill out a form during second shot. The nurses told her that her vaccine would only be 40% effective because of her cancer history as her PSH scores showed that she had a weakened immune system. she was a thyroid cancer patient survivor as her thyroid was removed surgically and was on hormone replacements for that, prior to the vaccines. They also tested her TSH scores. She has not had chemo but a month before the pandemic the doctor started doing labs to track her PSH levels and was going to change her thyroid hormone doses. She took a thyroid hormone replacement, levothyroxine. She stated sometimes if the dose was wrong, got heart palpitations. She stated she used to be on 112 mcg and now was on 75 mcg. She was hoping that doctor knew about endocrinology and had figured out why her hormone replacement was not as effective as it should be. They checked her labs but had not called and said that she had a better immune system. They kept pushing her procedures further and further without diagnosing her. They tested her for covid antibodies, but she tested negative. She had stoke, brain tumour that was inactive, vestibular issues, two corneal transplants, and she was blind. Additionally, she had a horrible reaction to the Shingrex vaccine in the past and mentioned that she got vaccines for everything as she was trying to live to be 90 years old. she was also on Reclast infusion one time a year for osteoporosis and wanted to know if that could affect the vaccine, she was recovering from back surgery, was in a car accident prior to the pandemic, she typically would get shots in her weaker arm as she had a broken wrist and nerve damage, prior to the vaccines; she was visually disabled, since before vaccines; she was a head and neck cancer, and stroke, prior to vaccines. She had a root canal that got infected in 2018 and it was like a slow infection, started prior to the vaccine which was reinfected between the two doses, had fever and chills. She thought it was a reaction to the second dose then realized it was the infection in her mouth. Hence, she saw her dentist. The outcome of the events was unknown.  No follow-up attempts are needed. No further information is expected.