Pt. went  to pharmacy on 6/22/21 to receive the second dose of Pfizer-BioNTech vaccine, lot number EW0177.  The day after the vaccine was administered, her lower arm was swollen, red and her elbow felt hot to the touch.  It was too painful to fully extend her arm.  There was a white streak across the reddish purple elbow area where it appeared as though there was an infection growing.  She went  to her normal doctors office, she saw his nurse practitioner who took an x-ray and gave her two intravenous injections of antibiotic (unknown type).  One in each buttock and prescribed an oral antibiotic: Cephalexin 500 mg., and Ibuprofen 800 mg. From that day forward she was unable to move the arm at all and the medication did not bring the swelling or the infection down.  She was very tired and her arm did not lessen in pain as the days passed.    On June 29, 2021 she was in her bedroom and her older daughter was in her room and believed her mother was resting.  At approximately 7:20 p.m., pts. husband returned from work and came into the master bedroom turning on the television.  As he did so he made joke expecting pt. to laugh or comment, when she made no response he looked over at her and saw that she was laying on the love seat at an awkward angle.  He moved to her side and saw her eyes were open but unseeing and saw that her dental prosthetic was partially pushed out of place.  He removed and called EMS immediately, not detecting any obvious signs of life.  Her daughter came into the room and immediately started CPR.  Paramedics arrived in under 2 minutes and moved pt. to the living room where they could intubate a breathing pathway and carried on with attempts to revive her heart muscle for approximately 25 minutes before Paramedic called time of death at 8:02 p.m.   Paramedics departed and the Police arrived staying  until the Mortuary attendants came to the home at about midnight to accept pt. body for transport to its facility.      The Family is seeking an autopsy and the coroner is claiming one is not necessary.  The family believes it is absolutely necessary to ascertain whether or not the second dose caused her death as it seems is likely and whether she should have been advised of her heighten risk level. Regardless of COVID 19 Emergency measures, an autopsy is necessary and the family is determined to ensure that it is conducted.   Pt. has had a history of the following: Adult onset Asthma, allergic reactions in skin rashes that were significant. Hypothrodism (Graves Disease) which proved to be difficult to find the right meds to bring it under control; prone to incidents of Atrial fibrillation which have escalated as she has aged; she has been treated for emergency visits for Tachycardia; she frequently has developed respiratory issues as a result of the asthma which often landed her  in  the emergency and days in the hospital on oxygen.  She often experienced shortness of breath and chest pain and last year underwent emergency appendicitis.  Her last episode of atrial fibrillation which landed in the hospital was 12/29/16.  She has been on anticoagulants for many years.    Since COVID 19 she may not have been able to afford her Eliquis prescription however which she did not disclose to any of her family members that she was struggling in this wasy.   She is likely not to have been taking her Hypothyrodism (Graves) medication either since these medications have not been recovered since her death.