FACIAL PALSY; RIGHT EYE HAD BLURRY VISION; URINARY RETENTION; NUMBNESS IN FEET WHICH ADVANCED TO COLLAR BONE; TINGLING IN FEET WHICH ADVANCED TO COLLAR BONE; BILTERAL WEAKNESS/BILTERAL LEG WEAKNESS; WALK WITH SUPPORT; PAIN; TWO LESIONS ON THORACIC SPINE AND ON LUMBAR; STROKE SYMPTOMS; This spontaneous report was received from a patient of unspecified age, sex. The patient's height, and weight were not reported. The patient's concurrent conditions included: alcohol use and the patient was non-smoker. The patient had no infectious illnesses nor any recent vaccinations or hospitalizations 6 weeks prior to onset of the event. The patient did not suffer from common cold, flu, or infection with epsteinBarr, herpes simplex, herpes Zoster, adenovirus infection, cytomegalovirus, respiratory syncytial virus infection, coxsackievirus, diarrhea or bloody diarrhea and lyme disease. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of administration, dose, vaccination site, and batch number not reported), 1 total, administered on 02-JUN-2021 for prophylactic vaccination. The batch number was not reported and has been requested. No concomitant medications were reported. On 15-JUN-2021, the patient experienced numbness and tingling in feet and urinary retention. The bowel was normal. The symptoms were started abruptly. The patient had bilateral weakness. The same day patient was referred to the ER, where blood and urine samples were taken, and multiple magnetic resonance imaging (MRIs) and computerized tomography (CT) scans were done. The ER doctor came back and said it was multiple sclerosis (MS), and patient was admitted to the hospital. An infectious disease (ID) doctor and a neurologist were assigned. Within 24 hours numbness and tingling had advance from feet to collar bone. The ID doctor prescribed treatments with unspecified intravenous anti viral and anti bacterial medications. The neurologist ordered a lumbar puncture with dozens of tests of the cerebral spinal fluid and more MRIs. Within 48 hours after receiving the anti viral patient was able to walk with support for short distances. Another 36 hours later patient could walk unassisted. After 9 days in the hospital, patient was feeling better and was released on 25-JUN-2021 and within an hour of being released, patient started having stroke symptoms and was rushed back to the ER. Brain CT scan was done, and it was determined that it was not a stroke but it was belle's palsy and guillain barré syndrome. Symptoms and parts of the body affected were bilateral leg weakness and facial palsy. Patient was then released again for outpatient treatment. Patient immediately saw a neurologist who reviewed  medical records, gave a shot of unspecified steroids, ordered more MRIs of spine, and gave an initial diagnosis of multiple sclerosis. Once he reviewed the MRIs with and without contrast he detected two lesions on thoracic spine along with lesions on lumbar spine. He then gave a diagnosis of thoracic myopathy and prescribed a five day infusion of Solu-Medrol (methylprednisolone sodium succinate). The treatment did not work, and patient was referred to the University for more research and another diagnosis. After more than two months, the patient still had no relief from pain and symptoms. The patient had difficulty in chewing and right eye had blurred vision. The patient tested negative for HIV and covid-19. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from numbness in feet which advanced to collar bone, urinary retention, stroke symptoms, two lesions on thoracic spine and on lumbar, bilteral weakness/bilteral leg weakness, facial palsy, right eye had blurry vision, walk with support, pain, and tingling in feet which advanced to collar bone. This report was serious (Hospitalization Caused / Prolonged, and Other Medically Important Condition).; Sender's Comments: V0- 20210840901- covid-19 vaccine ad26.cov2.s - Urinary retention , Facial palsy, Right eye blurry vision, Walk with support, Pain, two lesions on thoracic spine along with lesions on lumbar spine This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s). 20210840901- covid-19 vaccine ad26.cov2.s - Bilateral weakness/Bilateral leg weakness, Numbness had advance from feet to collar bone, Tingling had advance from feet to collar bone-. This event(s) is labeled and is therefore considered potentially related.