Extremely fatigued; Muscle pain in his quadriceps and muscles; Brain fog; Cough; Pain in his knees, arm, ankle, and joints; Pain in his knees, arm, ankle, and joints/arm tenderness; were just at the injection site /arm tenderness; This is a spontaneous report from a contactable consumer or other non hcp (Patient's wife). A 45-years-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Batch/Lot Number: Not Provided), dose 2 via an unspecified route of administration on 29Mar2021 (at the age of 45-years-old) as DOSE 2, SINGLE for covid-19 immunisation; adalimumab (HUMIRA), via an unspecified route of administration from an unspecified date (Batch/Lot Number: Not Provided) to an unspecified date, for psoriatic arthropathy. The patient's medical history included psoriatic arthropathy (Psoriatic arthritis). The patient's concomitant medications were not reported. The patient previously received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Batch/Lot Number: Not Provided), dose 1 via an unspecified route of administration on an unspecified date (at the age of 45-years-old) as DOSE 1, SINGLE for covid-19 immunisation. Caller calls on behalf of her husband. He had side effects after having the second shot of the Covid Vaccine 1 month ago on an unspecified date in 2021. Caller mentioned that for the last 7 days he experienced pain in his quads, a cough, fatigue, pain in his knees, arm, ankle, and joints, extreme fatigue, and brain fog. Her husband was also taking Humira for psoriatic arthritis. He was 45 years old with no underlying conditions. The caller mentioned that they got the second dose on 29Mar2021, and she and her husband experienced tiredness for 3 days and arm tenderness. Caller asks if there could be side effects a month after the vaccine. Caller comes on the line. She says that her symptoms were normal. Hers were just at the injection site and fatigue. She was more concerned about her husband. She had a hard time understanding the agent. She will just tell it again. She and her husband are 45 years old. They were both in good condition and healthier than most. Her husband has psoriatic arthritis and takes Humira. The arthritis was not always that bad. He doesn't take Humira at the regular dose. He takes it every 6 weeks, and it usually was supposed to be taken every 2 weeks. That was some background information on him. They had normal side effects after the second dose which were fine. They were good and everything was back to normal for 3 to 4 weeks. Now for the past 7 days he was extremely fatigued, has muscle pain in his quadriceps and muscles, and has brain fog. She was trying to figure out what was going on. She suggested that he get a Covid test. He had no breathing trouble and no fevers; it was just in his body. They were waiting for the results for the Covid test. She can't imagine it would be positive, but she hopes it was just to get to the bottom of this. She was wondering if his symptoms, when she reads about the symptoms that is kind of what he's having, but it's weird he was having them a month later. She was worried because she was online while she was talking, and it says Humira is an immune suppressant. That was how it works. Hopefully it doesn't conflict with the vaccine. She doesn't know how to really help him. What she was reading says taking something like Humira and the vaccine might not work. She would like to jump over to Medical Information now. She is slightly panicked and just wants to talk to them. Caller confirmed that her husband was extremely fatigued, had muscle pain in his quadriceps and muscles, and had brain fog and then wished to be transferred to Medical Information. Unable to confirm additional events with caller. While reporting an AE, caller mentioned that her husband got tested for Covid after receiving the Covid vaccine because they are concerned, he may have Covid. The outcome of the events was unknown.   No follow-up attempts are needed; information about lot/batch number cannot be obtained.