Doctor's opinion was that it was gbs, Guillain barre syndrome; lost control of the left side of her body; her face was numb; Her coworkers and other people that talked to her said that her left eye was twitching a lot.; When she was walking her arm was like limping; started feeling bad on her left side; her body, and her face felt like she almost had a stroke; still has facial paralysis and still has not gained it/she has no feeling in the left side of her face; This spontaneous case was reported by a consumer and describes the occurrence of CEREBROVASCULAR ACCIDENT (her body, and her face felt like she almost had a stroke), FACIAL PARALYSIS (still has facial paralysis and still has not gained it/she has no feeling in the left side of her face), GUILLAIN-BARRE SYNDROME (Doctor's opinion was that it was gbs, Guillain barre syndrome) and HEMIPARESIS (lost control of the left side of her body) in a 43-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 088D214) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The medical history information was not provided by the reporter.  Concomitant products included FREMANEZUMAB (AJOVY [FREMANEZUMAB]) for Migraine, BACLOFEN for Muscle relaxation, PROMETHAZINE for Nausea and Migraine, AMLODIPINE and TRIAMTERENE.    On 25-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Aug-2021, the patient experienced CEREBROVASCULAR ACCIDENT (her body, and her face felt like she almost had a stroke) (seriousness criterion medically significant), FACIAL PARALYSIS (still has facial paralysis and still has not gained it/she has no feeling in the left side of her face) (seriousness criterion medically significant), HEMIPARESIS (lost control of the left side of her body) (seriousness criterion medically significant), HYPOAESTHESIA (her face was numb), MUSCLE TWITCHING (Her coworkers and other people that talked to her said that her left eye was twitching a lot.), GAIT DISTURBANCE (When she was walking her arm was like limping) and FEELING ABNORMAL (started feeling bad on her left side). On an unknown date, the patient experienced GUILLAIN-BARRE SYNDROME (Doctor's opinion was that it was gbs, Guillain barre syndrome) (seriousness criterion medically significant). At the time of the report, CEREBROVASCULAR ACCIDENT (her body, and her face felt like she almost had a stroke), FACIAL PARALYSIS (still has facial paralysis and still has not gained it/she has no feeling in the left side of her face), HYPOAESTHESIA (her face was numb) and MUSCLE TWITCHING (Her coworkers and other people that talked to her said that her left eye was twitching a lot.) had not resolved and GUILLAIN-BARRE SYNDROME (Doctor's opinion was that it was gbs, Guillain barre syndrome), HEMIPARESIS (lost control of the left side of her body), GAIT DISTURBANCE (When she was walking her arm was like limping) and FEELING ABNORMAL (started feeling bad on her left side) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Amlodipine and Triamterene is taking for Blood pressure. Patient did not receive any treatment.  This case concerns a 43-year-old, female patient with previous relevant medical history of hypertension and use of concomitant medication amlodipine, who experienced the unexpected events of cerebrovascular accident, facial paralysis, Guillain-Barre Syndrome and hemiparesis. The events occurred 1 days after the first dose of mRNA-1273. The rechallenge was unknown since the events have not resolved.  The medical history of hypertension and use of concomitant medication remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This case concerns a 43-year-old, female patient with previous relevant medical history of hypertension and use of concomitant medication amlodipine, who experienced the unexpected events of cerebrovascular accident, facial paralysis, Guillain-Barre Syndrome and hemiparesis. The events occurred 1 days after the first dose of mRNA-1273. The rechallenge was unknown since the events have not resolved.  The medical history of hypertension and use of concomitant medication remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.