Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond; Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond; Still feels a little under the weather; Weak; Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond; Very tired; For the first 2 days, she was feeling lethargic and not wanting to eat or drink.; For the first 2 days, she was feeling lethargic and not wanting to eat or drink; For the first 2 days, she was feeling lethargic and not wanting to eat or drink; This spontaneous case was reported by a consumer and describes the occurrence of BLINDNESS TRANSIENT (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond), UNRESPONSIVE TO STIMULI (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond) and LETHARGY (For the first 2 days, she was feeling lethargic and not wanting to eat or drink.) in a 50-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 041B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Blood pressure high. Concomitant products included METOPROLOL, HYDRALAZINE, PRAZOSIN and ISOSORBIDE for an unknown indication.    On 14-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In August 2021, the patient experienced LETHARGY (For the first 2 days, she was feeling lethargic and not wanting to eat or drink.) (seriousness criterion medically significant), DECREASED APPETITE (For the first 2 days, she was feeling lethargic and not wanting to eat or drink), THIRST DECREASED (For the first 2 days, she was feeling lethargic and not wanting to eat or drink) and FATIGUE (Very tired). On 16-Aug-2021, the patient experienced BLINDNESS TRANSIENT (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond) (seriousness criteria hospitalization and medically significant), UNRESPONSIVE TO STIMULI (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond) (seriousness criteria hospitalization and medically significant) and DIZZINESS (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond). On an unknown date, the patient experienced ILLNESS (Still feels a little under the weather) and ASTHENIA (Weak). The patient was hospitalized on 16-Aug-2021 due to BLINDNESS TRANSIENT and UNRESPONSIVE TO STIMULI. At the time of the report, BLINDNESS TRANSIENT (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond), UNRESPONSIVE TO STIMULI (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond), DECREASED APPETITE (For the first 2 days, she was feeling lethargic and not wanting to eat or drink), THIRST DECREASED (For the first 2 days, she was feeling lethargic and not wanting to eat or drink), DIZZINESS (Blood pressure tanked so badly that she went blind and dizzy and she was not able to respond), ILLNESS (Still feels a little under the weather) and FATIGUE (Very tired) was resolving and LETHARGY (For the first 2 days, she was feeling lethargic and not wanting to eat or drink.) and ASTHENIA (Weak) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 16-Aug-2021, Blood pressure diastolic: 40 (Low) 40. On 16-Aug-2021, Blood pressure measurement: abnormal (abnormal) blood pressure tanked so badly.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       No additional treatment medication was provided.  On 14-Aug-2021, patient received first dose of Moderna COVID-19 vaccine in the left, non-dominant arm. For the first 2 days, she was feeling lethargic and not wanting to eat or drink and was very tired.  By 16-Aug-2021, the patient's blood pressure tanked so badly that she went blind and was dizzy and was not able to respond. Her husband called an ambulance, and patient was taken to emergency room and the diastolic blood pressure was 40.  The patient received fluids in ER, however they were not able to raise blood pressure hence patient was in the hospital for 2 days and 1 night.   Patient was tested for everything and everything else was ruled out and they concluded that this episode was from the vaccine.   Patient suffers from high blood pressure usually and no one warned about the problem the vaccine could have with blood pressure. Patient was home from the hospital and still feels a little under the weather, however overall feeling a little better and was still lethargic and weak.  Company Comment:  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  Further information is  expected.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  Further information is  expected.