Erythema multiforme; A rash at the base of his left pinky finger on the side of the palm/rash extended to the fleshy part of the palm of the thumb/also had in his feet / the rash appeared in his right palm; Red spots in the trunk of his body; Difficult to walk; The skin was puffy and it almost looked as if there were blisters, with liquid inside.; Palms were itching/Itch; Palms were burning; Could not sleep for three weeks; Still a little achy/painful to walk; Still has flare ups sometimes; Red spot in the face; This spontaneous case was reported by a consumer and describes the occurrence of ERYTHEMA MULTIFORME (Erythema multiforme) in a 71-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 028A21A and 040A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Skin biopsy (superficial and deep perivascular interstitial dermatitis with eosinophil urticarial", could change due to the medication taken: steroids and antihistamines) on 06-Jul-2021. Concomitant products included LOSARTAN, ROSUVASTATIN CALCIUM (CRESTOR), EZETIMIBE (ZETIA), SITAGLIPTIN PHOSPHATE (SILO) and ALFUZOSIN for an unknown indication.   On 13-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 10-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced ERYTHEMA MULTIFORME (Erythema multiforme) (seriousness criterion medically significant), RASH (A rash at the base of his left pinky finger on the side of the palm/rash extended to the fleshy part of the palm of the thumb/also had in his feet / the rash appeared in his right palm), RASH PAPULAR (Red spots in the trunk of his body), GAIT DISTURBANCE (Difficult to walk), SKIN SWELLING (The skin was puffy and it almost looked as if there were blisters, with liquid inside.), PRURITUS (Palms were itching/Itch), FEELING HOT (Palms were burning), INSOMNIA (Could not sleep for three weeks), PAIN (Still a little achy/painful to walk), CONDITION AGGRAVATED (Still has flare ups sometimes) and RASH ERYTHEMATOUS (Red spot in the face). The patient was treated with CORTISONE at an unspecified dose and frequency and FEXOFENADINE HYDROCHLORIDE (ALLEGRA) at a dose of 180 mg once a day. At the time of the report, ERYTHEMA MULTIFORME (Erythema multiforme), RASH (A rash at the base of his left pinky finger on the side of the palm/rash extended to the fleshy part of the palm of the thumb/also had in his feet / the rash appeared in his right palm), RASH PAPULAR (Red spots in the trunk of his body), GAIT DISTURBANCE (Difficult to walk), SKIN SWELLING (The skin was puffy and it almost looked as if there were blisters, with liquid inside.), PRURITUS (Palms were itching/Itch), FEELING HOT (Palms were burning), INSOMNIA (Could not sleep for three weeks), PAIN (Still a little achy/painful to walk), CONDITION AGGRAVATED (Still has flare ups sometimes) and RASH ERYTHEMATOUS (Red spot in the face) outcome was unknown.            Treatment medication information were provided as cream, allergist-immunologist that prescribed an injectable steroid and some medications were reduced to half a dose (blood pressure and ADD). Concomitant medication information were provided by reporter that includes water pill, hydrochlorosiaside sulfa based drug.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However, the medical history/ occurrence of superficial and deep perivascular interstitial dermatitis with eosinophil urticarial could be a contributory factor.