Fatigued; Headache; Nausea; Feeling tired, lethargic; I don't feel well, I was just felt worn out after the shower; Allergy; I started having lot of joint issue; This is a spontaneous report from a contactable consumer (patient). This 70-year-old female consumer (patient) reported for herself that she received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection), dose 2 via an unspecified route of administration, administered in left arm on 15Mar2021 (Lot Number: EN6204, expiration date not provided) as dose 2, single for COVID-19 immunization. The patient was 70-year-old at the time of vaccination. Medical history included hypertension, ongoing anxiety, interstitial cystitis, ongoing reflux, polymyalgia rheumatica and one kidney and then i have quarter of another kidney that functions. Historical Vaccine included BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, at 70-years), dose 1, single on unspecified date (Batch/Lot Number: not reported) as dose 1, single for COVID-19 immunization. Concomitant medications included amlodipine at 2.5 mg taken for anxiety, start and stop date were not reported; omeprazole taken at once a day for reflux, start and stop date were not reported; calcium carbonate, colecalciferol (CALTRATE 600 + D) taken for bones, start and stop date were not reported; prednisone at 3 mg, once a day per day taken for an unspecified indication, start and stop date were not reported; ascorbic acid, betacarotene, biotin, calcium carbonate, calcium pantothenate, calcium phosphate dihydrate, chromic chloride, colecalciferol, copper sulfate, cyanocobalamin, dl-alpha tocopheryl acetate, ferrous fumarate, folic acid, lycopene, magnesium oxide heavy, manganese sulfate monohydrate, nicotinamide, phytomenadione, potassium iodide, pyridoxine hydrochloride, retinol acetate, riboflavin, sodium selenate, thiamine mononitrate, xantofyl, zinc oxide (CENTRUM FOR WOMEN) taken for an unspecified indication, start and stop date were not reported. The patient received her 2nd Pfizer vaccine dose on 15Mar2021. "Late in the evening I got fatigued and headache, nausea. I feel pretty bad today." The patient also took 4 mg prednisone po daily for medical condition. "Is it ok to take the prednisone that have taken for a long time?" The patient asked if it was ok to take acetaminophen for pain following the vaccine. The patient had the 2nd Pfizer dose on 15Mar2021, and she was having some fatigue, headache and nausea. The patient stated "Yes, I didn't have any of that when I first got home from having the vaccine, the 2nd shot. I was going well and later that evening I just started feeling tired, lethargic and a little nausea where it then, I really don't feel. I haven't thrown up, but I feel when I eat. I don't feel well. I took a shower an hour ago and I was just felt worn out after the shower and I am a person that, I work a lot. I do have a little bit of allergy, but I know that's all-normal pretty typical side effect." The patient had Polymyalgia rheumatica and wanted to know should I take the vaccine. The patient added "I started having lot of joint issue and I went to my doctor to see the rheumatologist." The patient stated, "I do a Nasal spray (further details unknown)." stated, "I had a physical and everything was great. I have not taken anything.". The outcome of the events was unknown.   Information on lot/batch number was available. Additional information has been requested.  Follow-up (01Jul2021): Follow-up attempts completed. No further information expected.