perfuse sweating; First dose: felt a little icky and tired; elevated blood pressure; heart palpitations; First dose: felt a little icky and tired; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 55 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 13Apr2021 (Lot number: ER8729) at the age of 55 years as dose 1, single for covid-19 immunisation. Family history included: "Low thyroid" (unspecified if ongoing), notes: Her mother have low thyroid . Concomitant medication(s) included: ALLEGRA-D [FEXOFENADINE;PSEUDOEPHEDRINE HYDROCHLORIDE]; TYLENOL EXTRA taken for pain (ongoing). The following information was reported: FATIGUE (non-serious) with onset Apr2021, outcome "unknown", BLOOD PRESSURE INCREASED (non-serious) with onset 20Apr2021, outcome "not recovered" and all described as "elevated blood pressure"; PALPITATIONS (non-serious) with onset 20Apr2021, outcome "not recovered", described as "heart palpitations"; HYPERHIDROSIS (non-serious), outcome "not recovered", described as "perfuse sweating"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "First dose: felt a little icky and tired". The events "first dose: felt a little icky and tired", "elevated blood pressure", "heart palpitations", "perfuse sweating" and "first dose: felt a little icky and tired" were evaluated at the emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of fatigue, blood pressure increased, palpitations, hyperhidrosis, feeling abnormal.  Additional information: Time the vaccination was given between 08:00 and 09:00. No prior Vaccinations within 4 weeks. She received the first dose on 12Apr2021 and went back for the second dose of the vaccine on 04May2021. Her mother does have low thyroid. Not too long after receiving the first dose, she clarifies she did not have any immediate side effects she felt a little icky and tired for 24 hours but did not have anything noticeable. However, not long after that, she began to have nonstop, sort of fluctuating, but elevated blood pressure and heart palpitations. She began to develop something that felt like she was in a panic state or "fight or flight" state 24 hours a day. It was waking her up in the middle of the night. She felt like she was waking up violently. In the morning, she was waking up violently. She was constantly now having very elevated blood pressure and a lot of heart pounding. She has never had anxiety before but she now feels like she was living in a 24-hour-a-day state of really, really high level anxiety. Last Friday, after she took a shower, she was feeling like she was going to die. She does not know how else to explain it. She does have a blood pressure cuff and she decided to take her blood pressure. Her blood pressure was 209/100 and her heart rate was 125. Her blood pressure has been hovering around the 160s and 170's for the top number. She explains she and her doctors cannot get her to calm down. She called her doctor and she was sent to the Emergency Room. Some of the heart palpitation stuff and other things is coming in waves, it was not like its constant. But the blood pressure being elevated is constant. Also, when she has these waves, she also has perfuse sweating. The waves last for about 5 minutes and the perfuse sweating takes a long time to stop. Her body was wet and she was instantly drenched. She was post-menopausal for like 2 years, it was not like hot flashes or anything weird showing up at the same time. All of this seems like it has developed since she got the vaccine. It looks like some things were thrown off in the blood tests and stuff that were done in the ER. It was even showing that her thyroid was low and they immediately put her on synthroid thyroid medication which made her a little nervous. She was not sure that what was showing up was something that was systemic with her or if this was something effecting what was systemic with her or if she having some reaction. She was a little terrified right now to have her heart rate and blood pressure be up so much all the time. The level it was on Friday (209/100) scared her to death. She was not feeling normal and feels like she was dying all day long. Friday was the highest her blood pressure has ever been. When she tried to use blood pressure cuff, her arm turned dark red, went numb and tingly, and she had tons of pain. She thought her arm was going to explode. She has never had that happen. She thinks the blood pressure was so high that the cuff caused that to happen. This made her think her blood pressure was close to heart attack level. Her blood pressure was 209/100 and her heart rate was 125. Her arm had never done that before. Several things were showing up weird in her blood tests. One of the things that showed up was that her thyroid was slightly low. She clarifies the TSH level was elevated, which meant hypothy-roidism (thyroid is low). She was immediately put on Synthroid even though she was telling the doctors she was not so sure if what was happening to her was systemic and that it may be some-thing that is exacerbated by or caused by the vaccine. She had to call into an endocrinologist be-cause wanted her to see the endocrinologist immediately. In the hospital, her heart rate was okay while she was there, this kind of goes in waves. A wave of her heartbeat going really, really hard and really, really fast. However, on the regular, like all of the time, for example, like right now as she is speaking with the call handler, she has been shaking and she can tell her blood pressure is elevated. She has taken her blood pressure twice this morning and it was in the 180s over 90s range and then in the 160/80's range. Constantly, she feels like her heart was racing around and her blood pressure was racing all day long. It feels like what an anxiety attack would feel like. It was like she just can't get her body to calm down. Patient usually takes the Allegra-D regularly but when she started having these heart palpitations and high blood pressure, she stopped taking the Allegra-D 12HR because of the Sudafed. She thought it was probably not a good idea. It hasn't changed or alleviated any of the symptoms, but she did stop taking the Allegra-D 12 Hour at that point. She clarifies she has been taking this medication for a really long time and hadn't had any problems but thought if her blood pressure was up and her heart was racing, she should remove the Sudafed from the situation. She does kind of take Tylenol regularly for daily pain. She clarifies she takes it as needed, but if she does take it in a full day, she takes 4 doses of 2 tablets a day, every 5 hours which is the recommendation on the bottle. She clarifies they are 500mg tablets, and she will take 2 tablets every 5 hours as needed; 1000mg at time.   No follow-up attempts are possible. No further information is expected.