Disability; Infected my nervous system; still sick; can't do daily exercise; my condition gotten worse; i am not well; I am getting is my hair keep pulling string and on my face; legs feel like they are wrapped around something; did not get the second dose/received the first dose of the Moderna COVID-19 vaccine on 17Mar2021; high blood pressure/high blood pressure; Stiff neck and arm/stiff neck; Hard to concentrate; muscle pain like a string being pulled; Body drains after exercise/when exercising their body feels drained; Crawling all over body/feeling that something is crawling all over their body; Tingling/poking feeling under the arms/poking feeling in their head; Popping of skin/popping feeling of the skin; Sensation of skin numbness/skin numbness; Body drains after exercise and cant do daily exercise anymore/ when exercising their body feels drained/ Felt weak; Hard time breathing/still having a hard time breathing/pressure on her breathing/shortness of breath; Chest pain; Feeling of electricity on their feet when the car is running; Feels like an alien is traveling through her body/When she first got the shot, she felt this thing that ran across her chest/feeling like something is flying all over; Anxiety/Her nervous system is affected. It feels like she is losing oxygen in her head and then it "locks up"/anxiety; Sweating; Cold/started to get warm; Popping feeling/pressing on her muscle of her arms and chest; Pressure on her muscles; This spontaneous case was reported by a consumer and describes the occurrence of DISABILITY (Disability) and NEUROLOGICAL INFECTION (Infected my nervous system) in a 54-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 001B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Penicillin allergy (Took a sister medication of it before, but then broke out into a rash later.), Anxiety and Blood pressure high. Concomitant products included HYDROCHLOROTHIAZIDE, LORAZEPAM and DULOXETINE for an unknown indication.    On 17-Mar-2021 at 10:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In March 2021, the patient experienced CHEST DISCOMFORT (Popping feeling/pressing on her muscle of her arms and chest), MUSCLE STRAIN (Pressure on her muscles), HYPERHIDROSIS (Sweating) and FEELING OF BODY TEMPERATURE CHANGE (Cold/started to get warm). On 20-Mar-2021, the patient experienced DYSPNOEA (Hard time breathing/still having a hard time breathing/pressure on her breathing/shortness of breath), CHEST PAIN (Chest pain), HYPERTENSION (high blood pressure/high blood pressure), MUSCULOSKELETAL STIFFNESS (Stiff neck and arm/stiff neck), ELECTRIC SHOCK SENSATION (Feeling of electricity on their feet when the car is running), FEELING ABNORMAL (Feels like an alien is traveling through her body/When she first got the shot, she felt this thing that ran across her chest/feeling like something is flying all over), ANXIETY (Anxiety/Her nervous system is affected. It feels like she is losing oxygen in her head and then it "locks up"/anxiety), PARAESTHESIA (Tingling/poking feeling under the arms/poking feeling in their head), SKIN EXFOLIATION (Popping of skin/popping feeling of the skin), HYPOAESTHESIA (Sensation of skin numbness/skin numbness), ASTHENIA (Body drains after exercise and cant do daily exercise anymore/ when exercising their body feels drained/ Felt weak), FORMICATION (Crawling all over body/feeling that something is crawling all over their body), DISTURBANCE IN ATTENTION (Hard to concentrate), MYALGIA (muscle pain like a string being pulled) and FATIGUE (Body drains after exercise/when exercising their body feels drained). On an unknown date, the patient experienced DISABILITY (Disability) (seriousness criterion medically significant), NEUROLOGICAL INFECTION (Infected my nervous system) (seriousness criterion medically significant), ILLNESS (still sick), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (can't do daily exercise), CONDITION AGGRAVATED (my condition gotten worse), MALAISE (i am not well), HAIR DISORDER (I am getting is my hair keep pulling string and on my face), LIMB DISCOMFORT (legs feel like they are wrapped around something) and PRODUCT DOSE OMISSION ISSUE (did not get the second dose/received the first dose of the Moderna COVID-19 vaccine on 17Mar2021). The patient was treated with DULOXETINE ongoing since an unknown date at an unspecified dose and frequency; LORAZEPAM ongoing since an unknown date at an unspecified dose and frequency; IBUPROFEN (ADVIL [IBUPROFEN]) at an unspecified dose and frequency; ALBUTEROL [SALBUTAMOL] from 17-Mar-2021 to 18-Mar-2021 for Asthma, at a dose of UNK, prn and CICLESONIDE (ALVESCO) at a dose of UNK, prn. At the time of the report, DISABILITY (Disability), NEUROLOGICAL INFECTION (Infected my nervous system), CHEST PAIN (Chest pain), HYPERTENSION (high blood pressure/high blood pressure), MUSCULOSKELETAL STIFFNESS (Stiff neck and arm/stiff neck), ELECTRIC SHOCK SENSATION (Feeling of electricity on their feet when the car is running), ASTHENIA (Body drains after exercise and cant do daily exercise anymore/ when exercising their body feels drained/ Felt weak), ILLNESS (still sick), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (can't do daily exercise), CONDITION AGGRAVATED (my condition gotten worse), MALAISE (i am not well), FORMICATION (Crawling all over body/feeling that something is crawling all over their body), HAIR DISORDER (I am getting is my hair keep pulling string and on my face), DISTURBANCE IN ATTENTION (Hard to concentrate), MYALGIA (muscle pain like a string being pulled), FATIGUE (Body drains after exercise/when exercising their body feels drained), LIMB DISCOMFORT (legs feel like they are wrapped around something) and PRODUCT DOSE OMISSION ISSUE (did not get the second dose/received the first dose of the Moderna COVID-19 vaccine on 17Mar2021) outcome was unknown and DYSPNOEA (Hard time breathing/still having a hard time breathing/pressure on her breathing/shortness of breath), CHEST DISCOMFORT (Popping feeling/pressing on her muscle of her arms and chest), MUSCLE STRAIN (Pressure on her muscles), FEELING ABNORMAL (Feels like an alien is traveling through her body/When she first got the shot, she felt this thing that ran across her chest/feeling like something is flying all over), ANXIETY (Anxiety/Her nervous system is affected. It feels like she is losing oxygen in her head and then it "locks up"/anxiety), HYPERHIDROSIS (Sweating), FEELING OF BODY TEMPERATURE CHANGE (Cold/started to get warm), PARAESTHESIA (Tingling/poking feeling under the arms/poking feeling in their head), SKIN EXFOLIATION (Popping of skin/popping feeling of the skin) and HYPOAESTHESIA (Sensation of skin numbness/skin numbness) had not resolved.        mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Most recent FOLLOW-UP information incorporated above includes: On 02-Aug-2021: Follow-up received. AE Start date and treatment drug updated, concomitant medications added. On 02-Aug-2021: Upon internal review on 16-SEP-2022 non significant corrections performed to update case received from field.; Sender's Comments: Based on reporter's causality (and any other explanation worth adding) the event is assessed as unlikely related to mRNA-1273.