severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching; chest pain radiating into neck; chest pain radiating into neck/ left side of neck swelling and aching; both armpits swelling and itching extreme/ left side of neck swelling and aching; inside of right elbow were itching, swelling and medium pain; inside of right elbow were itching, swelling and medium pain/ severe pain in both shoulders which radiated down to hips; both wrists were itching and both hands were swelling with severe pain; wrist itching/ both heels were itching/ inside of right elbow were itching, swelling and medium pain/ both armpits swelling and itching extreme; hand swelling/ toes were swollen; This is a spontaneous report from a contactable consumer, the patient. A 54-year-old male patient received the second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 Vaccine), via an unspecified route of administration, administered in left arm on 26Apr2021 08:45 (Batch/Lot Number: ER8736) (at the age of 54-years-old) as 2nd dose, single for COVID-19 immunization. Medical history was none. The patient had no known allergies. Concomitant medication included methylphenidate hydrochloride (RITALIN) 20mg ER. The patient previously received the first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 Vaccine), via an unspecified route of administration, administered in left arm on 29Mar2021 08:45 (Batch/Lot Number: EN6204) (at the age of 54-years-old) as 1st dose, single for COVID-19 immunization. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Prior to vaccination, the patient was not diagnosed with COVID. Since the vaccination, the patient had not been tested for COVID-19. On 27Apr2021 at 09:00 (day after injection) on the same arm, the patient experienced wrist itching and hand swelling (left). On the next evening on 28Apr2021, both wrists were itching and both hands were swelling with severe pain, lasted 3 hours then they went away completely. The next day on 29Apr2021 at 03:00, both heels were itching, toes were swollen mildly with almost no pain. The next day on 30Apr2021, inside of right elbow was itching, swelling and medium pain. The next day on 01May2021, there was nothing. The next day on 02May2021, both armpits swelling and itching extreme with severe pain in both shoulders which radiated down to hips after 1 hour started to go to emergency room (ER) but it all vanished completely. Sometimes the patient got a day break but otherwise, since 27Apr2021 this had happened to some part of his body (most commonly in hands) up to Friday 28May2021. The patient was put on second round of steroids and now antihistamines and he hadn't had any symptoms for 2 days. The severe itching and pain also occurred at other locations such tongue, inside of cheeks, throat, and chest pain radiating into neck, left side of neck swelling and aching. The patient had never had similar symptoms before. The events resulted in doctor or other healthcare professional office/clinic visit. The patient received treatment medications to lessen swelling and pain. The outcome of events was unknown.