Booster; vaccine_location=Left leg; My leg developed a softball size welt; Discoloration; itching on my inner arms, upper chest and back that last about 10-20 minutes; Allergic reaction; Developing rashes (that look like little bubbles on my skin); itching about 2-3 days after I received the dose; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 45 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in leg left, administration date 01Dec2021 08:30 (Lot number: FT8762) at the age of 45 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Breast Cancer", start date: Nov2020 (unspecified if ongoing), notes: I had breast cancer in Nov2020 and radiation treatment 28Dec 2020 - 26Jan2021; "Known allergies: pineapple" (unspecified if ongoing), notes: Pineapple; "Known allergies: Sulfas" (unspecified if ongoing); "COVID-19" (unspecified if ongoing), notes: Prior to vaccination, was the patient diagnosed with COVID-19:Yes; "radiation treatment", start date: 28Dec2020, stop date: 26Jan2021, notes: radiation treatment 28Dec2020 - 26Jan2021. Concomitant medication(s) included: TAMOXIFEN; PROTONIX [OMEPRAZOLE]; MICARDIS; LEXAPRO. Past drug history included: Doxycycline, reaction(s): "Known allergies: Doxycicline". Vaccination history included: Bnt162b2 (Dose Number: 2, Batch/Lot No: EM9809, Location of injection: Arm Left, Vaccine Administration Time: 04:00 PM), administration date: 10Feb2021, when the patient was 44 years old, for COVID-19 immunization, reaction(s): "rashes", "allergic reaction", "Lymphedema", "itching on my inner arms, upper chest and back"; Bnt162b2 (Dose Number: 1, Batch/Lot No: EI9263, Location of injection: Arm Left, Vaccine Administration Time: 04:30 PM), administration date: 20Jan2021, when the patient was 44 years old, for COVID-19 immunization. The following information was reported: IMMUNISATION (non-serious) with onset 01Dec2021 08:30, outcome "unknown", described as "Booster"; PRODUCT ADMINISTERED AT INAPPROPRIATE SITE (non-serious) with onset 01Dec2021 08:30, outcome "unknown", described as "vaccine_location=Left leg"; URTICARIA (non-serious) with onset Dec2021, outcome "not recovered", described as "My leg developed a softball size welt"; SKIN DISCOLOURATION (non-serious) with onset Dec2021, outcome "not recovered", described as "Discoloration"; PRURITUS (non-serious) with onset Dec2021, outcome "recovered" (Dec2021), described as "itching on my inner arms, upper chest and back that last about 10-20 minutes"; HYPERSENSITIVITY (non-serious) with onset Dec2021, outcome "not recovered", described as "Allergic reaction"; RASH (non-serious) with onset Dec2021, outcome "not recovered", described as "Developing rashes (that look like little bubbles on my skin)"; PRURITUS (non-serious) with onset Dec2021, outcome "not recovered", described as "itching about 2-3 days after I received the dose". The events "my leg developed a softball size welt", "discoloration", "itching on my inner arms, upper chest and back that last about 10-20 minutes", "allergic reaction", "developing rashes (that look like little bubbles on my skin)" and "itching about 2-3 days after i received the dose" were evaluated at the physician office visit. Therapeutic measures were taken as a result of urticaria, skin discolouration, pruritus, hypersensitivity, rash, pruritus. No follow-up attempts are possible. No further information is expected.  Additional information : It was reported that patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient received Tamoxifen, Protonix, Micardis, Lexapro, vitamins within 2 weeks of vaccination. Patients leg developed a softball size welt, discoloration and itching about 2-3 days after received the dose. On day 5, patient went to the urgent care and they said that he had an allergic reaction to the site. In addition, on day 7, patient started developing rashes (that look like little bubbles on my skin) and itching on my inner arms, upper chest and back that last about 10-20 minutes. The same thing happened after second dose and lasted about 2 months. Patient spoke to dermatologist and internist in the spring and both were confused. Now that it has started again after the booster, patient believed that there is a corelation.Treatment received for the adverse event with Benadryl and Tylenol. Patient has not been patient been tested for COVID-19 since vaccination. No prolonged hospitalization.  Follow-up attempts are completed. No further information is expected..