tingling to the feet, arms and hands; numbing to the feet, arms and hands; vitamin D was low; anxiety; palpitations; bumpy hives in left side of face, the same side of the body as the shot; rash and bumpy hives in left side of face; This is a spontaneous report from a contactable nurse (patient). A 67-year-old female patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot Number: EN6200), via an unspecified route of administration, administered in arm left on 25Feb2021 (at the age of 67-years-old) at 0.3 mL, single for COVID-19 immunisation. Medical history included chronic back pain and hysterectomy from an unknown date and unknown if ongoing. Concomitant medications included metoprolol (METOPROLOL XL SANDOZ) taken for blood pressure abnormal; estradiol taken for an unspecified indication, both start and stop dates were not reported. Clinical course was as follows: The reporter was worried sick and wanted to confirm that what she has had is what other people are having. Had the Pfizer first dose on 25Feb2021 and second dose on 18Mar2021, 21 days after. A couple of hours after the first dose, had a rash and hives on one side of the face, the same side of the body as the shot. Went away the next day. Between the first and second dose, one arm was having tingling and numbing to the feet, arms and hands. Got worse and worse after the second shot. Went to primary doctor 2 times, who said that it is her immune system reacting to the Covid vaccine. It has been almost four weeks, will be four weeks this Thursday after the second shot. Is getting worried. Read up something saying that people may have multisystem inflammatory system response. Read this in the Covid 19 information from Pfizer. Confirmed that caller is referring to the Covid 19 vaccine. As she is talking now, her left arm and feet are tingling. Has doctor appointment tomorrow to rule out anything in the spine. Has a history of back pain. Back pain never causes tingling like this, only pain and is not usually in her arm. Even talking now, forearm is tingling and the feet. As a nurse, she is thinking it could be all kinds of diseases. She thought to herself does she have MS or ALS, but the doctor tested everything, and all tests were negative, there is nothing that supports any sort of muscular problem. Decided to call Pfizer to see if anyone else has tingling. Saw primary doctor 09Apr2021, has another appointment tomorrow behind her back. Has to rule everything out, so she may need an MRI. Has chronic back pain, it hurts, but usually no tingling. This has gone on many years with no tingling. It is in her hand and forearm. Read today for the first time that it may be multisystem inflammatory syndrome. Has been seen in the office two times for the numbing and tingling. They tested her for Lupus, and everything was normal. Just her vitamin D was low. Event details was as follows: Numbing and tingling: Started right after first shot, 25Feb2021, like a week after. Rash and bumpy hives in left side of face: and to neck, was in same side of body as shot which was in the left arm. Started 6 hours after the first shot. Was a bumpy rash but no itching. Looked at her face and could feel the bumps. Went away the next day and really subsided. Could feel a little bit but not bumpy. Lasted a few hours over night. Treatment: Put some diphenhydramine (BENADRYL) cream on it. Did not have rash after second dose of the vaccine. Numbing and tingling: After the second shot on 18Mar2021, saw the doctor, on 22Mar2021, 4 days after the second shot, for the numbness and tingling. The tingling had gone down from a 10 to a 6 or 7. Has been having anxiety and palpitations. These symptoms occurred a week after the shot. She never thought about the shot. Treatment: nothing for numbness and tingling. Was told to take naproxen sodium (ALEVE), but nothing major. Has not been taking anything. Tomorrow at 2:00pm, has appointment with spine doctor to see what he thinks. Has never had tingling before with the back pain and no tingling in the arms, why in the arms. The outcome of the events bumpy hives in left side of face, the same side of the body as the shot and rash and bumpy hives in left side of face was recovered on 26Feb2021, while of the rest was unknown.