From initial information received on 4/14/04 from another manufacturer, regarding an adverse event occurring in the USA: Information has been received regarding a case in litigation concerning a minor male child who during his first two years of life was subjected to very high doses of mercury contained through his infant injections. On 6/22/98 he was vaccinated with a first dose of hepatitis B virus vaccine. Subsequently, two months later, on 8/4/98, a second dose of hepatitis B virus vaccine (lot # 6254398/0112H) was administered IM in the right thigh, and on 5/24/99 a third dose (lot # 629354-1739H) was administered in the left leg. Other vaccines containing the mercury-based preservative thimerosal that he received during his first two years of life included the following: diphtheria toxoid (+) pertussis acellular vaccine (+) tetanus toxoid; a first dose (lot # 0939790) in the left leg at age 8 weeks, on 8/29/98, a second dose (lot # 0962260) in the right leg at age four months on 11/9/98; a third dose in the right at age 7 months, on 1/28/99, and a 0.5cc fourth dose (lot # PMUM56FA) in the right thigh at 18 months of age, on 12/29/99; HIB conjugate vaccine, a first dose (lot # 0960510) in the right leg at age eight weeks on 8/28/98, a second dose (lot # 0988200) in the left leg at age four months on 11/9/98, a third dose in the left thigh at age seven months on 1/28/99, and a fourth dose of HIB conjugate vaccine (lot # 628809/1453H) in the right arm on 7/23/99l and in May 2000 at age 23 months he was administered 0.5cc of pneumococcal 4 6B 9V 14 18C 19F 23F conjugate vaccine (lot # 471208) in the left leg. The alleged result is that the minor child was poisoned by the cumulative doses of mercury in thimerosal, and now suffers, and in the future will continue to suffer from the neurological effects of mercury poisoning, including extreme physical pain, emotional distress, mental anguish, humiliation and deformity all as a result of a cumulative exposure to mercury in thimerosal-adulterated infant injections that were administered to him during the first two years of his life. The patient's vaccination records also noted that the patient had received the following vaccinations: a first dose of poliovirus vaccine inactivated SC in the left leg on 8/4/98, a second dose of poliovirus vaccine inactivated SC in the left leg on 11/9/98, and a third dose of poliovirus vaccine inactivated at age 18 months, on 12/29/99; a dose of varicella virus vaccine live in the left arm on 7/23/99, and a dose of MMR on 9/27/99. Additional information has been received from medical records regarding a case in litigation concerning a minor male child. The medical record, an authorization and informed consents form for Hepatitis B immunization, was signed by the minor male patient's family on 6/21/98. The consent form confirms that the minor male received his first dose of hepatitis B virus vaccine on 6/22/98. Upon internal review, poisoned by the cumulative doses of mercury in thimerosal, suffers from neurological effects of mercury poisoning, extreme physical pain, emotional distress, mental anguish, humiliation and deformity were considered to be other important medical events (OMIC). No further information is available. The patient reportedly did not recover from this event. From additional information received on 11/3/04 from another manufacturer, it was reported, Additional follow up information indicated that he had not suffered a side effect of allergic reaction to any medication, other than the vaccines containing thimerosal. He has been diagnosed with several food sensitivities. His parents indicated that he became very irritable and lethargic and developed a fever after receiving several of the vaccinations. They cannot recall the specific vaccines that caused the reaction. He has been diagnosed with and treated for Pervasive Developmental Disorder/Autism Spectrum Disorder. His neurological condition and impairments are associated with the administration of his vaccines in that the thimerosal containing vaccines were substantial factors in causing these injuries and conditions. He has undergone Autism related blood testing, urinalysis and hair testing which has demonstrated the presence of heavy metals and necessitating chelation therapy. He has never received a transfusion of the whole blood, plasma, blood products or any other fluids (including but not limited to immunoglobulin or gammaglobulin treatments). He lost the ability to use facial expressions and smile, maintain eye contact and use words at approximately 16 months. At the time of the report, the patient could say hundreds of words to label items, repeat phrases of jargon, and get attention. However, he is still incapable of using language to have a conversation or reciprocal communications with an adult or peer. His parents recall that the first signs or symptoms of his neurodevelopmental delay occurred when he demonstrated uneven physical and verbal skills at about 13 months. At that time, he preferred to be alone, demonstrating difficulty in expressing his needs and in interacting with others. As a result of the injuries, his family was required to completely change their family's lifestyle to provide him with round-the-clock intensive behavior programming through the use of one-on-one assistants trained by certified behavior consultants. He has made steady and slow progress with these treatments, but still suffers from autism. It is possible that he was exposed to mercury of other substances (other than thimerosal) containing mercury, but his parents are not aware of any specific date or extent of exposure. His mother did not breast feed him. She was never exposed to any caustic or toxic substances, x-rays or communicable diseases from the date one year prior to his birth until the date of birth. Nor was she involved in any accident of any kind, incluidng falls, impacts with any objects or other types of bodily injury, from the date one year prior to his birth. She is unaware of having any dental fillings with mercury. Genetic testing or counseling chromosome analysis has not ever been recommended or conducted on the patient or any member of his family. Neither the patient or any member of his family has ever been diagnosed with any psychological disorder. Neither the patient or any member of his family has ever had any immune dysregulation. In or about 2001, a physician recommended against vaccinations due to the high levels of toxic metals in the vaccines. Also, in the same time frame, it was felt that the patient's autism was caused by high levels of toxic metals. Potential contributing factors include other exposure to mercury beyond that contained in the vaccines, exposure to aluminum in vaccines, exposure to antibiotics, and the child's genetic or other form of susceptibility to toxic insult. Upon internal review, poisoned by the cumulative doses of mercury in thimerosal, suffers from neurological effects of mercury poisoning, extreme physical pain, emotional distress, mental anguish, humiliation and deformity. Pervasive Developmental Disorder/Autism Spectrum, and neurodevelopmental delay were considered to be other important medical events (OMIC). It was noted that the patient's cousin was diagnosed with autism after following the same vaccination schedule (WAES0410USA04441). No further information is anticipated, this case is considered closed.