Loss of Appetite and Taste; Loss of Appetite and Taste; Weight Loss of approximately 20-22 pounds; pancreatitis; pancreatic carcinoma; issues were related to her spine; Small Fiber Neuropathy/ class C fibers; Pain/ most intense pain ever felt in her left upper back; extends downward primarily on her left side; Stomach Pain; Blurred Vision/ not focusing as well; eyes feeling tired; by 11 AM she begins to experience different, unspecified symptoms; This case was reported by a consumer via call center representative and described the occurrence of pancreatitis in a 70-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included cataract (might had prior to vaccination).   On 4th January 2019, the patient received the 1st dose of Shingrix (intramuscular). On 8th January 2019, 4 days after receiving Shingrix, the patient experienced pancreatitis (serious criteria hospitalization and GSK medically significant), pancreatic carcinoma (serious criteria hospitalization and GSK medically significant), spinal disorder (serious criteria hospitalization), small fiber neuropathy (serious criteria hospitalization), upper back pain (serious criteria hospitalization), pain of lower extremities (serious criteria hospitalization), stomach pain (serious criteria hospitalization), blurred vision (serious criteria hospitalization) and tired eyes (serious criteria hospitalization). On an unknown date, the patient experienced appetite lost (serious criteria hospitalization), taste loss (serious criteria hospitalization), weight loss (serious criteria hospitalization) and adverse reaction. Shingrix was discontinued. On an unknown date, the outcome of the pancreatitis, pancreatic carcinoma, spinal disorder and adverse reaction were unknown and the outcome of the small fiber neuropathy, upper back pain, pain of lower extremities, stomach pain, blurred vision and tired eyes were not recovered/not resolved and the outcome of the appetite lost, taste loss and weight loss were recovering/resolving.   It was unknown if the reporter considered the pancreatitis, pancreatic carcinoma, spinal disorder, small fiber neuropathy, upper back pain, pain of lower extremities, stomach pain, blurred vision, tired eyes, appetite lost, taste loss, weight loss and adverse reaction to be related to Shingrix.  Additional details were provided as follows: The reporter was patient's husband and he was a medical doctor for dermatology. The patient received Shingrix in her left deltoid. On 8th January 2019, she developed a number of symptoms, some of which precede to the day of reporting.  The patient described her pain as most intense pain ever felt in her left upper back that sometimes extended downward primarily on the left side that was somewhat variable as far as occurrence or re-occurrence.  The patient had been hospitalized twice and diagnosed with small fiber neuropathy and class C fibers that persisted till the day of reporting.  After extensive evaluations, different doctors of different practices thought, the patient might had pancreatitis or pancreatic carcinoma, and there were also questions whether issues were related to her spine.  Due to stomach pain, the patient's gall bladder was removed but that was ineffective as far as stomach pain management.  She also had blurred vision and she described it as starting from the top, eyes feeling tired and not focusing as well.  The patient was seen by an optometrist and would be evaluated for cataracts. The reporter stated, she might have had cataracts prior to vaccination.  The patient had loss of appetite, weight loss of approximately 20 to 22 pounds and a loss in her taste which was slowly becoming a little better.  The patient's typical day starts as being in fair shape in mornings but by 11 AM, she begins to experience different, unspecified symptoms. She then typically went in bed by 8 PM and that she sleeps well and wakes up in good shape every day. The reporter did not want to consent to follow-up to his wife's healthcare professional without her permission.