neurological issues/symptoms not sleeping; neurological issues/symptoms not sleeping; day was ok just some tender arm, but within 36-48 hours of booster dose nurse told her she has covid arm in her Left arm, swelling like a tennis ball; her feet/hands were twitching; body was on fire, burning, felt like pins and needles coming out from her upper and lower extremities; body was on fire, burning, felt like pins and needles coming out from her upper and lower extremities; menstrual cycle  changed with second dose but it got worse after the booster; her menstrual cycle was abnormal which meant a longer, heavier and earlier cycle; her menstrual cycle was abnormal which meant a longer, heavier and earlier cycle; her menstrual cycle was abnormal which meant a longer, heavier and earlier cycle; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 44-year-old female patient received BNT162b2 (BNT162B2), on 04May2022 as dose 3 (booster), single (Batch/Lot number: unknown) at the age of 44 years for covid-19 immunization. The patient's relevant medical history included: "menstrual cycle changed" (unspecified if ongoing), notes: menstrual cycle changed with second dose, but it got worse after the booster its early and heavy (like when she was in her 20s). The patient took concomitant medications. Vaccination history included: Bnt162b2 (Dose: 1, Lot number: ER8732), for Covid-19 immunization; Bnt162b2 (Dose: 2), for Covid-19 Immunization, reaction(s): "menstrual cycle was abnormal which meant a longer, heavier and earlier cycle", "the second dose she had typical side effects, flu like symptoms for 5-6 days, changes in the menstrual cycle,"; Bnt162b2 (Dose: 2), for Covid-19 immunization, reaction(s): "the second dose she had typical side effects, flu like symptoms for 5-6 days, changes in the menstrual cycle,", "menstrual cycle was abnormal which meant a longer, heavier and earlier cycle". The following information was reported: NERVOUS SYSTEM DISORDER (non-serious), INSOMNIA (non-serious), outcome "unknown" and all described as "neurological issues/symptoms not sleeping"; PERIPHERAL SWELLING (non-serious), outcome "unknown", described as "day was ok just some tender arm, but within 36-48 hours of booster dose nurse told her she has covid arm in her Left arm, swelling like a tennis ball"; MUSCLE TWITCHING (non-serious), outcome "unknown", described as "her feet/hands were twitching"; PARAESTHESIA (non-serious), BURNING SENSATION (non-serious), outcome "unknown" and all described as "body was on fire, burning, felt like pins and needles coming out from her upper and lower extremities"; CONDITION AGGRAVATED (non-serious), outcome "unknown", described as "menstrual cycle changed with second dose but it got worse after the booster"; MENSTRUAL DISORDER (non-serious), OLIGOMENORRHOEA (non-serious), POLYMENORRHOEA (non-serious), outcome "unknown" and all described as "her menstrual cycle was abnormal which meant a longer, heavier and earlier cycle". Therapeutic measures were taken as a result of nervous system disorder, insomnia, peripheral swelling, muscle twitching, paraesthesia, burning sensation, condition aggravated, menstrual disorder, oligomenorrhoea, polymenorrhoea.  Additional information: Stated that the flu like symptoms and menstrual changes started after the second dose. Stated that in the first 24 hours that the injection site was tender and that in 36 hours that she had Covid arm and the more pronounced swelling extending outward and within few hours that she got the neuro stuff from her knees to feet and elbows to arms. Clarified that her left arm was tender and she had Covid arm and swelling to her left arm. Stated that she was told to put a circle around it and monitor and that it was width of a bicep. Stated that she did take antihistamines and Tylenol. Stated that her menstrual cycle was abnormal which meant a longer, heavier and earlier cycle that she noticed after the second dose and with the booster. Stated that with the pill that she had predictability and controlled all that she knew flow and predictable. No further details wished to be provided. Stated that she is in a lot of discomfort and that her menstrual cycle is hard to manage. Stated that her menstrual cycle is atypical. Stated that after the booster that it was modulating her menstrual cycle and that she had called to see if there was any correlation. Wanted to know if they are doing research that may have been reported in the clinical trials about menstrual symptoms. Stated that she did see before deciding to call in empirical journals that menopausal women had bleeding after the booster. Stated that she is not menopausal but considers her symptoms significant. Stated that she had the booster on 04May and experienced bleeding a few days after that. Stated that she called the CDC and local public health department since the reaction was worst this time. Wanted to know where to point her with the booster this year or next year as to whether or not to receive it. Wanted to know if they are developing the vaccine and if it is the same vaccine rollout or tweaks or changes based upon how patient's responded if she did Pfizer again this year or 6 months from now. Wanted to know if the company was transitioning the vaccine or if it would be the same vaccine. Caller rambling on despite attempts to redirect. Unable to clarify information. Wanted to know if the lot number helps pinpoint batches of the drug.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200695996 similar report from same reporter