lymph nodes in left jaw began to swell; lymph nodes in left armpit and most recently, left inner thigh began to swell; left inner thigh began to swell; Lymph nodes inflame more during PMS; it also affects left breast; Right armpit lymph nodes are becoming agitated from a few days ago; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 36 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm right, administration date 27Jul2021 14:00 (Lot number: EW0168) at the age of 35 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Depression" (unspecified if ongoing); "possible PMDD" (unspecified if ongoing); "Neck injury" (unspecified if ongoing); "Known allergies: Sulfa drugs (IV)" (unspecified if ongoing); "Known allergies: Onions" (unspecified if ongoing); "Known allergies: Cinnamon" (unspecified if ongoing). Concomitant medication(s) included: ASPIRIN [ACETYLSALICYLIC ACID]; VITAMIN C [ASCORBIC ACID]; CALCIUM. Vaccination history included: Bnt162b2 (Dose Number: 1, Batch/Lot No: EW0180, Location of injection: Arm Left, Vaccine Administration Time: 02:00 PM), administration date: 22Jun2021, when the patient was 35 years old, for COVID-19 immunization, reaction(s): "pressure in head (especially behind eye balls)", "First vaccination gave dull pain", "During this time, pressure formed and released in several places such as legs and arms.", "During this time, pressure formed and released in several places such as legs and arms.". The following information was reported: LYMPHADENOPATHY (non-serious) with onset 2021, outcome "not recovered", described as "lymph nodes in left jaw began to swell"; LYMPHADENOPATHY (non-serious) with onset 2021, outcome "not recovered", described as "lymph nodes in left armpit and most recently, left inner thigh began to swell"; PERIPHERAL SWELLING (non-serious) with onset 2021, outcome "not recovered", described as "left inner thigh began to swell"; LYMPHADENITIS (non-serious) with onset 2021, outcome "not recovered", described as "Lymph nodes inflame more during PMS"; BREAST DISCOMFORT (non-serious) with onset 2021, outcome "not recovered", described as "it also affects left breast"; LYMPH NODE PAIN (non-serious) with onset 2021, outcome "not recovered", described as "Right armpit lymph nodes are becoming agitated from a few days ago". The events "lymph nodes in left jaw began to swell", "lymph nodes in left armpit and most recently, left inner thigh began to swell", "left inner thigh began to swell", "lymph nodes inflame more during pms", "it also affects left breast" and "right armpit lymph nodes are becoming agitated from a few days ago" were evaluated at the physician office visit and emergency room visit. Therapeutic measures were taken as a result of lymphadenopathy, lymphadenopathy, peripheral swelling, lymphadenitis, breast discomfort, lymph node pain.  Additional information: Patient had not received other vaccines within 4 weeks prior to the COVID vaccine. Patient had received other medications the patient received within 2 weeks of vaccination was Aspirin, Vitamin C, Calcium, Multi Vitamin. Patient had not diagnosed with COVID-19 prior to vaccination. Patient not been tested for COVID-19 since the vaccination. First vaccination gave dull pain, pressure in head (especially behind eyeballs). This pressure eventually receded over approx 3 weeks. During this time, pressure formed and released in several places such as legs and arms. After second vaccination, lymph nodes in left jaw began to swell. Weeks after, lymph nodes in left armpit, and most recently, left inner thigh began to swell. Lymph nodes inflame more during PMS, monthly cycle, where it also affects left breast. Right armpit lymph nodes are becoming agitated from a few days ago.  Follow-up attempts are completed. No further information is expected.