second dose in Aug2021; She had a mini stroke; she was going to developed gangrene; her speech was slurred; His mother couldn't walk; had to be spoon fed many times/She had to be help to be fed, change clothes, and walk to the toilet; Her toe swelled up; She had infection of toe and toenail. It turned bluish red.; One leg got larger than the other as far as muscle mass/One leg shrank; Then she couldn't use her hands anymore because she was so weak/Her hands almost became nonfunctional; fatigue; body aching; was sleeping all the time; The initial case was missing the following minimum criteria: no adverse event. Upon receipt of follow-up information on 12Oct2021, this case now contains all required information to be considered valid.  This is a spontaneous report received from a contactable consumer. This consumer reported for 89-year-old female patient (reporter's mother) received bnt162b2 (BNT162B2) via unspecified route of administration in right arm, in Aug2021 at DOSE 2, SINGLE for COVID-19 immunisation at the age of 88 years old. Medical history included Diabetes, diagnosed over 40 to 45 years ago. High blood pressure, diagnosed about 20 years ago. Glaucoma, diagnosed about 20 years ago, Cholesterol, diagnosed about 15 to 20 years ago. Heart condition, Her heart was not very strong. He is not sure if she is on medication or not. All her issues are interrelated. Thyroid cancer, she is a cancer survivor. She had thyroid cancer probably 20 years ago. It was the most treatable cancer. Stage 3 Colorectal Cancer, had it 10 to 15 years ago. It was in remission. Concomitant medication included insulin porcine (INSULIN). Before when she was a diabetic they gave her Metformin tablets. In the last 10 to 15 years they switched from tablets to insulin shots. She was on Metformin a long time ago.  The patient previously received first dose of bnt162b2 on 10Jun2021 for COVID-19 immunisation and experienced that site with soreness was minimal. She received second dose of vaccine in the mid or end of Aug2021. She had a mini stroke after that.  The mini stroke was a few days or a week or so after the second dose. No one knew she had the stroke. She lives with his sister and she took the little signs for granted. It was when the reporter spoke to his mother and her speech was slurred that he said something. His mother couldn't walk and had to be spoon fed many times. His sister thought she had the wrong dentures in. When she went to the diabetic check they found it. She had other side effects. Her toe swelled up. The reporter thought she was going to developed gangrene. Maybe it was her right leg. She had infection of toe and toenail. It turned bluish red. It went away but took a while. One leg got larger than the other as far as muscle mass. One leg shrank. That was after the Pfizer shot. That is when he told his sister that something was not right. That is when the doctor did CT scan and discovered mini stroke. The reporter clarified Right after second shot, 2 days after shot, that is when she couldn't walk and one leg became smaller than the other. Then she couldn't use her hands anymore because she was so weak. Her hands almost became non-functional. She had to be help to be fed, change clothes, and walk to the toilet. That was after the second shot. Then she developed the toe infection that was scary looking. It took a long time to go away because she is diabetic. That is why he was nervous about gangrene. She couldn't walk or use her hands a few days or a week at most after the second shot. Nobody knew when the stroke came. It is possible the stroke also effected her ability to use her hands and walk. That is why he felt that the stroke came from the vaccine because it effects her hands, legs, and speech. No one had linked them together. He asked the nurse there about his mother's condition. The first thing the nurse asked was if his mom had a stroke. The doctor said she had a mini stroke and is now on a medication, Apo-Clopidogrel 75mg. That is when he decided to research the stroke. He found the link between the vaccine and stroke and Pfizer and J&J. After second shot she was fatigue, had body aching, and was sleeping all the time. His mother has always been very active. she enjoys gardening. Before the vaccine shot she gardened a lot and exercised and plays with her cat. She has not be able to do those things. Essentially she is bed ridden. Events did not require a visit to Emergency Room or Physician Office. The outcome of events was unknown.   The lot number for the vaccine BNT162B2, was not provided and will be requested during follow up.