on either side by the pelvic bone- its like a pressure more than a pain; Every single time she goes to the bathroom there is blood on her butt.; severe blood pouring out of her rectum; nausea/queasiness in stomach; severe pain in jaw and temples; burned like heck; severe pain in jaw and temples; head pain; inflammation; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 56 year-old female patient received bnt162b2 (COMIRNATY), administered in arm left (top of her left arm), administration date 14Dec2021 16:00 (Lot number: FD7218) at the age of 56 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "caller had covid before getting the vaccine" (unspecified if ongoing), notes: she would get the temperature with covid in the evening and at night; "had a rash with the virus" (unspecified if ongoing); "rash with the virus and it was itchy" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Polio (A few years ago the caller got the booster dose for Polio because her titers were low), for Immunization. The following information was reported: HAEMORRHAGE (medically significant) with onset 17Dec2021, outcome "not recovered", described as "Every single time she goes to the bathroom there is blood on her butt."; RECTAL HAEMORRHAGE (medically significant) with onset 17Dec2021, outcome "not recovered", described as "severe blood pouring out of her rectum"; PAIN IN JAW (non-serious), HEADACHE (non-serious) all with onset 14Dec2021, outcome "recovering" and all described as "severe pain in jaw and temples"; THERMAL BURN (non-serious) with onset 14Dec2021, outcome "unknown", described as "burned like heck"; BONE PAIN (non-serious) with onset 09Jan2022, outcome "not recovered", described as "on either side by the pelvic bone- its like a pressure more than a pain"; INFLAMMATION (non-serious) with onset Dec2021, outcome "unknown", described as "inflammation"; HEADACHE (non-serious) with onset 14Dec2021, outcome "unknown", described as "head pain"; NAUSEA (non-serious) with onset 15Dec2021, outcome "unknown", described as "nausea/queasiness in stomach". The events "every single time she goes to the bathroom there is blood on her butt.", "severe blood pouring out of her rectum", "severe pain in jaw and temples", "burned like heck", "on either side by the pelvic bone- its like a pressure more than a pain", "inflammation", "severe pain in jaw and temples" and "nausea/queasiness in stomach" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: colonoscopy: (04Jan2022) rectal bleeding partial with diffuse inflammation; investigation: (unspecified date) she had antibodies; sars-cov-2 test: (unspecified date) negative; weight: (unspecified date) 125 kg, notes: 125 kg.  Clinical Course: Patient symptoms included severe pain in jaw and temples, nausea and queasiness in stomach, severe blood pouring out of her rectum. She has an upcoming appointment with the doctor on Monday where they will do tests. She adds that when she got the initial injection it ''burned like heck''. severe jaw and head pain started hours after. She had a colonoscopy done, where after the results her doctor asked her more questions about the vaccine so she has a feeling it might be related. Patient would like something in writing from Pfizer to share with her HCP on delaying her 2nd dose of the Pfizer covid vaccine due to her reaction to the 1st dose still being under medical investigation. Got the shot on 14Dec2021. That same day a couple of hours later, the patient started to get severe pain in her jaw and temples of her head. The patient was not surprised by this because she knew this was one thing she heard happens. The next day, the patient had that plus nausea and queasiness in her stomach that went on for the day after as well. Then on 17Dec2021, the patient had severe blood pouring out of her rectum and lasted 1-2 minutes, it felt like a lifetime. Since then, the patient has been getting the same symptoms. The jaw and temple pain was not constant but the patient gets it throughout the day The queasiness was more frequent and the rectal bleeding was 1-4 times a day. Every single time she goes to the bathroom there was blood on her butt. A gastroenterologist and did a colonoscopy and wouldn't even consider this was from the vaccine. After the doctor did the colonoscopy she started to question the patient about the vaccine. The doctor has no idea what the bleeding was inflammation but doesn't understand it. Patient was not getting pain, which started yesterday, on either side by the pelvic bone- its like a pressure more than a pain. Patient can put her finger on the two spots where she feels it. Patient has a CAT scan with contrast for next week because she doesn't know what to do. The doctor was trying to figure it out. Patient pain in her jaw and temples was the same level but not a constant thing, it hits more during the afternoon and night. The patient had covid before getting the vaccine and she would get the temperature with covid in the evening and at night. Patient was getting this pain at the same time and its much worse at night. 2 days ago the pain in the patient jaw and temples started to back off. Patient goes to the bathroom there was blood there when she touches it with toilet paper. Patient bowel movements have not changed and they're normal.