Redness in the eyelids; Puffiness in the eyelids; Pain in my back; It was hard to do anything with my arms; Numbness in my hands/50% of numbness in my fingers of both hands/(numbness) was going to the whole finger/partial numbness only/the middle finger was the worst; Much more severe pain; similar symptoms to carpal tunnel/mild case of carpal tunnel on the left side/moderate case of carpal tunnel on the right side; Feel pressure in my neck, where the thyroid gland is; Pain went to my right knee, underneath the knee/pain in the right shoulder/pain is similar to rheumatoid arthritis; (Pain) went to my left calf on my leg/pain was also in both arms (in the triceps)/was not able to sleep on my right side/pain went to both thighs/pain in my hands; This spontaneous case was reported by a consumer and describes the occurrence of ERYTHEMA OF EYELID (Redness in the eyelids), PERIORBITAL SWELLING (Puffiness in the eyelids), BACK PAIN (Pain in my back), MOBILITY DECREASED (It was hard to do anything with my arms) and HYPOAESTHESIA (Numbness in my hands/50% of numbness in my fingers of both hands/(numbness) was going to the whole finger/partial numbness only/the middle finger was the worst) in a 61-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 002C21A and 026B21A.) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included LEVOTHYROXINE SODIUM (SYNTHROID) and CALCIUM CARBONATE, COLECALCIFEROL (VITAMIN D 2000) for an unknown indication.   On 01-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 29-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced ERYTHEMA OF EYELID (Redness in the eyelids), PERIORBITAL SWELLING (Puffiness in the eyelids), BACK PAIN (Pain in my back), MOBILITY DECREASED (It was hard to do anything with my arms), HYPOAESTHESIA (Numbness in my hands/50% of numbness in my fingers of both hands/(numbness) was going to the whole finger/partial numbness only/the middle finger was the worst), PAIN (Much more severe pain), CARPAL TUNNEL SYNDROME (similar symptoms to carpal tunnel/mild case of carpal tunnel on the left side/moderate case of carpal tunnel on the right side), MUSCLE TIGHTNESS (Feel pressure in my neck, where the thyroid gland is), ARTHRALGIA (Pain went to my right knee, underneath the knee/pain in the right shoulder/pain is similar to rheumatoid arthritis) and MYALGIA ((Pain) went to my left calf on my leg/pain was also in both arms (in the triceps)/was not able to sleep on my right side/pain went to both thighs/pain in my hands). The patient was treated with NAPROXEN at an unspecified dose and frequency; METHYLPREDNISOLONE on 18-Aug-2021 at an unspecified dose and frequency and DEXAMETHASONE SODIUM PHOSPHATE (CORTICOIDEX) at an unspecified dose and frequency. At the time of the report, ERYTHEMA OF EYELID (Redness in the eyelids), PERIORBITAL SWELLING (Puffiness in the eyelids), BACK PAIN (Pain in my back), MOBILITY DECREASED (It was hard to do anything with my arms), HYPOAESTHESIA (Numbness in my hands/50% of numbness in my fingers of both hands/(numbness) was going to the whole finger/partial numbness only/the middle finger was the worst), PAIN (Much more severe pain), CARPAL TUNNEL SYNDROME (similar symptoms to carpal tunnel/mild case of carpal tunnel on the left side/moderate case of carpal tunnel on the right side), MUSCLE TIGHTNESS (Feel pressure in my neck, where the thyroid gland is), ARTHRALGIA (Pain went to my right knee, underneath the knee/pain in the right shoulder/pain is similar to rheumatoid arthritis) and MYALGIA ((Pain) went to my left calf on my leg/pain was also in both arms (in the triceps)/was not able to sleep on my right side/pain went to both thighs/pain in my hands) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In July 2021, C-reactive protein (0-4): 17 (High) C reactive protein test at the beginning of July (it shows if there is any kind of inflammation).         Patient started to go to physical therapy (electrodes, and massage), patient was not feeling better with this therapy, so patient was prescribed with Methylprednisolone On 03Sep2021, patient had an EMG test. Neurologist checked her nerves, mild case on the left side of carpal tunnel, and moderate case on the right side of carpal tunnel. Treatment information included Pain killers, topical creams.