This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID: Unknown. The reporter is the parent. A 30-year-old female patient received BNT162b2 (BNT162B2), as dose 2, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, Batch/Lot number: unknown, ), for COVID-19 immunization, reaction(s): "She can barely walk", "she has not driven or worked in over 17 months", "intense pain", "eye sight has diminished". The following information was reported: BLINDNESS (disability, medically significant), outcome "unknown", described as "Losing vision/Her eye sight has diminished"; DISABILITY (disability), outcome "unknown", described as "Disabled after second shot/daughter is about 95% disabled"; PAIN (disability), outcome "unknown", described as "She is in intense pain, even on pain meds"; GAIT DISTURBANCE (disability), outcome "unknown", described as "She can barely walk"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (disability), outcome "unknown", described as "She has not driven or worked in over 17 months"; MUSCLE DISORDER (disability), outcome "unknown", described as "Muscle control lost". The events "losing vision/her eye sight has diminished", "disabled after second shot/daughter is about 95% disabled", "she is in intense pain, even on pain meds", "she can barely walk", "she has not driven or worked in over 17 months" and "muscle control lost" required emergency room visit. Therapeutic measures were taken as a result of pain. Clinical course: Father reported that her 30-year-old daughter is about 95% disabled. She is in intense pain, even on pain meds. She can barely walk and has seen dozens of specialists. None of the specialist have been helpful. This all started in Apr2020. This all started within hours of getting the 2 shot of the Pfizer vaccine. (2 shot protocol). She needs relief. Her eyesight has diminished and she has not driven or worked in over 17 months. You guys are the experts. What can be done to help her? What can you do to help her? The reason for no lot number: of Pfizer COVID-19 vaccine as caller was unwilling to complete the report. Caller has got a number on an email, which he received the email from Pfizer Medical Information department, where they were responding to his email from when he contacted them about the Pfizer COVID-19 vaccine. He says his question is for his daughter, and he had not reported anything to Pfizer at this point. Over the weekend he sent them the question because his daughter is disabled and she was perfectly healthy before her second shot a year and a half ago, then almost immediately after her second shot she began losing vision and muscle control. She has been in and out of the ER several times, she is in extreme pain all the time. He is desperate so he is reaching out to Pfizer who has immunity, which he didn't ask for anything, and he almost knows for a fact because he knows one other person in the same condition as his daughter, she is not the only one. His question is about his daughter being disabled after second shot, because he has got to believe since Pfizer put out that medication, that other people have contacted them with the same, and they might have information that if there are things that can be done to help and they have to be doing something for people. His daughter hasn't worked or drove in a year, she is 30 years old, she wasn't disabled until 18 months ago. Pfizer makes a wonderful drug for everything, and he sent the email out of frustration, no one can do anything. His daughter when she sleeps is great, but when she wakes up she is in excruciating pain. Caller mentioned that Pfizer must have had similar reports and that he hopes that Pfizer can do something to help. Caller later stated that her daughter has no future. Callback attempt #1 was provided on 12Sep2022 at 12:38 pm per attached guidance. Able to leave voicemail with phone number and case number. The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.