Arm is swollen/ Size of grapefruit/ Three quarters away on arm, that big/ Initially it was like a grapefruit, now it is like an orange/ A patch quite big, 2 inches in circumference each way; Developed blisters at the injection site/ Already been 3 days and it kept spreading/ Almost like a surgical burn; 2 inches in circumference each way, of blisters that are quite painful/ Very painful/ Blisters that are quite painful; Almost like a fever blister/ The heat is tremendous; Hardened spot that was very painful and hot, it was just getting bigger and bigger; Extremely hot to the touch/ Hardened spot that was very painful and hot/ The heat is tremendous; Hardened spot that was very painful and hot, it was just getting bigger and bigger; This spontaneous case was reported by a consumer and describes the occurrence of PERIPHERAL SWELLING (Arm is swollen/ Size of grapefruit/ Three quarters away on arm, that big/ Initially it was like a grapefruit, now it is like an orange/ A patch quite big, 2 inches in circumference each way), VACCINATION SITE VESICLES (Developed blisters at the injection site/ Already been 3 days and it kept spreading/ Almost like a surgical burn), PAIN (2 inches in circumference each way, of blisters that are quite painful/ Very painful/ Blisters that are quite painful), ORAL HERPES (Almost like a fever blister/ The heat is tremendous) and VACCINATION SITE INDURATION (Hardened spot that was very painful and hot, it was just getting bigger and bigger) in a 63-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 017E21A, 013A21A and 030L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hypertension and Overweight. Concomitant products included SULFAMETHOXAZOLE;TRIMETHOPRIM for Adverse event, LISINOPRIL for Blood pressure high.   On 01-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PERIPHERAL SWELLING (Arm is swollen/ Size of grapefruit/ Three quarters away on arm, that big/ Initially it was like a grapefruit, now it is like an orange/ A patch quite big, 2 inches in circumference each way), VACCINATION SITE VESICLES (Developed blisters at the injection site/ Already been 3 days and it kept spreading/ Almost like a surgical burn), PAIN (2 inches in circumference each way, of blisters that are quite painful/ Very painful/ Blisters that are quite painful), ORAL HERPES (Almost like a fever blister/ The heat is tremendous), VACCINATION SITE INDURATION (Hardened spot that was very painful and hot, it was just getting bigger and bigger), FEELING HOT (Extremely hot to the touch/ Hardened spot that was very painful and hot/ The heat is tremendous) and VACCINATION SITE PAIN (Hardened spot that was very painful and hot, it was just getting bigger and bigger). The patient was treated with PARACETAMOL (TYLENOL) for Adverse event, at an unspecified dose and frequency. At the time of the report, PERIPHERAL SWELLING (Arm is swollen/ Size of grapefruit/ Three quarters away on arm, that big/ Initially it was like a grapefruit, now it is like an orange/ A patch quite big, 2 inches in circumference each way), VACCINATION SITE VESICLES (Developed blisters at the injection site/ Already been 3 days and it kept spreading/ Almost like a surgical burn), PAIN (2 inches in circumference each way, of blisters that are quite painful/ Very painful/ Blisters that are quite painful), ORAL HERPES (Almost like a fever blister/ The heat is tremendous), VACCINATION SITE INDURATION (Hardened spot that was very painful and hot, it was just getting bigger and bigger), FEELING HOT (Extremely hot to the touch/ Hardened spot that was very painful and hot/ The heat is tremendous) and VACCINATION SITE PAIN (Hardened spot that was very painful and hot, it was just getting bigger and bigger) had not resolved.            No concomitant medication was reported by patient.  The patient had not experienced any side effect after the first dose.  The patient was putting ice on arm where the blisters were formed and was taking Tylenol.   On an unknown date, the patient went to urgent clinic because it had already been three days and it kept spreading. The patient was given an antibiotic called Sulfameth/Trimethoprin 800/160MG and was asked to watch it if it gets bigger.   This case was linked to MOD-2021-294186 (Patient Link).