she had a huge knot in her arm and it has grown to 3 places in her left arm; had problems that night; I almost stop breathing; I had not been able to walk; without having to sit down and rest; I had not been able to walk; without having to sit down and rest; taken her feeling out of her left hand; When the pain gets so bad I wanna throw up; big knot that came up on my arm and it was really swollen, really sore; her grip has become weak; fatigue; big knot that came up on my arm and it was really swollen, really sore; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 57-year-old female patient received bnt162b2 (BNT162B2), via an unspecified route of administration, administered in arm left, administration date 29Jul2021 (Lot number: EW0179) at the age of 57 years as dose 1, single for covid-19 immunization. Relevant medical history included: "Asthma" (unspecified if ongoing). The patient took concomitant medication for asthma.  The following information was reported: NODULE (medically significant) with onset 29Jul2021, outcome "not recovered", described as "she had a huge knot in her arm and it has grown to 3 places in her left arm"; GRIP STRENGTH DECREASED (non-serious) with onset 2021, outcome "unknown", described as "her grip has become weak"; FATIGUE (non-serious) with onset 2021, outcome "unknown", described as "fatigue"; PAIN IN EXTREMITY (non-serious), PERIPHERAL SWELLING (non-serious) all with onset 2021, outcome "unknown" and all described as "big knot that came up on my arm and it was really swollen, really sore"; DYSPNOEA (non-serious) with onset 29Jul2021, outcome "recovered" (Oct2021), described as "had problems that night; I almost stop breathing"; GAIT INABILITY (non-serious) with onset Jul2021, outcome "recovered" (Oct2021), described as "I had not been able to walk; without having to sit down and rest"; VOMITING (non-serious) with onset 2021, outcome "unknown", described as "When the pain gets so bad I wanna throw up"; HYPOAESTHESIA (non-serious) with onset 2021, outcome "unknown", described as "taken her feeling out of her left hand". The event "she had a huge knot in her arm and it has grown to 3 places in her left arm" resulted in physician office visit. The patient underwent the following laboratory tests and procedures: magnetic resonance imaging (MRI): (2021) looks normal; x-ray (x-rays): (2021) looks normal. Therapeutic measures were taken as a result of nodule, pain in extremity, peripheral swelling. Additional information: After the patient received the Pfizer COVID-19 vaccine last 29Jul2021, the patient had a huge knot in her arm and it has grown to 3 places in her left arm, and it has also appeared in her left leg last week. It is also appearing in her right arm now. It has cut of her circulation in her hand and her grip has become weak. She said that she now has limited use in her left hand and arm. She also said that she has a high level of fatigue. She said that she basically had to rest while walking from her kitchen to her bedroom. She used to run 9 miles before. She also used to carry 15lbs now she can only carry a carton of milk. She wanted to know if those have been reported as adverse events for the vaccine and what to do to treat her adverse events. It was also reported that since the vaccination, there was a big knot that came up on her arm and it was really swollen, really sore. The patient had problems that night where she was 'later', where she almost stopped breathing and that went from 29Jul2021 until Oct2021 where I could not lift anything with my arm. On the patient's left side, she could not carry anything over a like a gallon of milk and she was carrying 50 pounds sac of dog food 3 days before the injection on her shoulder. She was walking 9 miles a week 'as unlike' and had not been able to walk to her bedroom and to the kitchen without having to sit down and rest and this was from Jul2021 until the end of Oct2021. Since that time, the patient's left arm has 3 huge knots in it now and they are growing almost 6-8 inches long and she should say that each one has taken her feeling out of her left hand where the more she uses her arm, the less she can hold, can grip, can grasp, and can lift her arm up. There is a place, that started at Christmas (25Dec2021) behind her left leg and this last week there is three places in her right arm that is starting to grow. So, the patient had X-rays and MRIs and they say that it looks normal. The patient is being scheduled for an EMG. The patient asks how to treat it because it is getting worse. The knots were growing all over her body. The patient has lost the use of her right arm now. Since Thursday of last week, the places started growing in her right arm and the patient believes that she was losing the feeling in it. The patient was losing stability to grasp and hold pencils or pen.  The patient is in fear now due to the events. The patient saw her doctors because of the knots in her arm and the doctors saw that there was a deformity in the patient's arm. The patient's doctors have no clue on what this was.   Follow-up attempts are completed. No further information is expected.