Whole arm was numb; Instant weird sensation; A tingling/Pins and needles from her arm, up her neck to her face, like having Novocain; Injection site soreness; This is a spontaneous report from a contactable consumer (patient). A 45-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, Lot Number: EW0181), dose 1 via an unspecified route of administration, administered in Arm Left on 02Jul2021 at 17:30 (at the age of 45-year-old) as single dose for covid-19 immunisation. Patient history included hormone therapy, oral contraception and overactive thyroid, patient stated that her thyroid was killed off with radioactive iodine, which she clarifies was done because it was overactive and they could not get it under control, so they went that way. She said it was probably 9 years ago when she had that done. she had blood work done for her thyroid, like her TSH level, but that was two months ago. No further details provided about her blood work results. The patient had covid-19 in Nov2020. Concomitant medications included levothyroxine sodium (UNITHROID, NDC: 60846080701)) taken for hormones, start and stop date were not reported and Ethinylestradiol, norgestimate (ORTHO TRI-CYCLEN, NDC: 68462056529, LOT: 20200624 and Expiration date: Sep2022, Manufacturer: Glenmark Pharmaceuticals taken as birth control pill, start and stop date were not reported. The patient had no other vaccines the day she got her Pfizer COVID-19 vaccine, or recently before getting it. On 02Jul2021, within 30 seconds of getting the shot, the patient experienced instant weird sensation, a tingling/pins, and needles from her arm, up her neck to her face, like having Novocain and whole arm was numb and also experienced injection site soreness. The clinical course of the events as follows: first dose of the Pfizer Covid-19 Vaccine on 02Jul2021. She experienced an instant weird sensation, within 30 seconds of getting the shot, a tingling from her arm, up her neck to her face, like having Novocain. The whole arm was numb, and it lasted for 3 hours and went away. The patient reported that her daughter got her vaccine on the same day, since she got it at the same time, the same vaccine from Pfizer, and did not have the reaction. she had an instant weird sensation, and she was alright now but she called the CDC, the Department of Health, and her primary care provider and none of them answered her question. she mentioned that she had pins and needles like when your arm is asleep, like when you sleep on it and this went up her arm to her neck and face. She said that it was like getting Novocain, it was tingly which lasted about 3 hours and then it went away. She reported she got the vaccine late in the day, so it was about time to go to bed. She stated during the early evening and had injection site soreness, so she thought she would go to bed and ignore the sensation, and in the morning, it was gone. She said she did no treatment for the events and tried to occupy herself and let it go away. Relevant tests were none. No Investigation assessment was provided. She wanted to know since it could have been allergic reaction or a reaction get worse with the second one, and she wanted the second dose, but knows the second dose reactions could be worse reactions sometimes, and someone said they could have hit a nerve when they injected her. The outcome of the events was resolved on an unspecified date in Jul2021   Follow up (02Aug2021): Follow-up attempts have been completed and no further information is expected.