felt like she had to go to the bathroom really bad; diarrhea/explosive diarrhea; vomiting/throwing up; abdominal pain/stomach pains; nausea; This is a spontaneous report from a contactable consumer (patient) via Medical Information Team. A 56-year-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Lot Number: EW0150; Expiration Date: Jul2021), via an unspecified route of administration in left on 22Jun2021 at 10:30 (at the age of 56 years old) as single for COVID-19 immunisation. Medical history included she had been seeing a gastroenterologist. She lost 145 lbs. in the last 4 years and she had problems with her digestive system since she had her gall bladder removed. Anything that she ate, after she ate it, it came out quickly as a bowel movement. She had gastrointestinal problems before but not recently, not lately. It was been well over a year and a half since she had problems with her GI system. She also had some other different surgeries as well as her tailbone was removed last year. She was in an abusive relationship for 15 years and her tailbone was broken, the bone was off to the side, her tailbone removed due to fracture from abusive relationship. She reported anesthesia made her sick. She had some back problems, and she was going through worker's compensation for a broken leg, but that had nothing to do with the COVID 19 vaccine. She did not take any prescription medications. She reported anesthesia made her sick. The doctor usually put a patch behind her ear before surgery. She got nauseous with anesthesia. There were no concomitant medications. Historical vaccine included first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Lot number: ER8729), via an unspecified route of administration in left on 01Jun2021 (at the age of 56 years old) as 0.3mL for COVID-19 immunisation and experienced no reaction. The patient did not receive any other vaccination within four weeks prior to the first administration date of the suspect vaccine. She and her partner both received the second COVID 19 vaccine together at about 22Jun2021 at 10:30AM. They were both observed for 15 minutes after the vaccine and everything was fine. She reported on the way home she felt as if she needed to use the restroom very badly. Once she got home, she had explosive diarrhea and vomiting. She ran into the house and it came out of every orifice. She was reporting abdominal pain, nausea, diarrhea, and stomach pains. She had a history of gastrointestinal disorders since her gallbladder has been removed and as soon as she ate then she immediately needed to use the restroom. She confirmed that she had been doing well with not having to utilize the restroom as much for a year and half. Her partner was fine and not had any side effects. She was asking if this was a normal reaction. She went to get her COVID 19 vaccine with an empty stomach. She stated she thought the vaccine might make her sick if she had eaten prior to getting it. The patient reports her partner took the same vaccine and only she experienced the stomach pains on the way home. She felt like she had to go to the bathroom really bad and when she did it was explosive diarrhea and throwing up. She is asking if there is anything that is like what she is experiencing. She and her partner had the COVID 19 vaccine at the same time and her partner had not any adverse effects. Event did not require a visit to: emergency room or physician office. No relevant tests were performed. The outcome of events was not recovered.  No follow-up attempts were possible. No further information was expected.