vegetative state; hallucinating; got very sick; stopped doing house chores,  she wouldn't get out of bed, can't sit up on her own; forgot to pay her bills, memory started lapsing.; completely bed ridden; can't speak; can't swallow, fed through a PEG tub; feels like pins and needles through her body, like she is being electrocuted through electrical shock; complete personality change; cognitive; behavioral; confused; agitated; apathetic; extremely fatigued; speech was slurred; cannot sleep, has not slept since september, does not have the physical ability to fall asleep or stay asleep. She cannot sleep for more than 5-10 minutes at a time; right eye was blurry; This spontaneous case was reported by a consumer and describes the occurrence of APALLIC SYNDROME (vegetative state) and HALLUCINATION (hallucinating) in a 64-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. Unknown) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included CEVIMELINE HYDROCHLORIDE (EVOXAC) for Saliva decreased, SERTRALINE HYDROCHLORIDE (ZOLOFT), ALPRAZOLAM (XANAX) and ZOLPIDEM TARTRATE (AMBIEN) for an unknown indication.   On 30-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 28-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In July 2021, the patient experienced VISION BLURRED (right eye was blurry). In September 2021, the patient experienced DYSARTHRIA (speech was slurred) and INSOMNIA (cannot sleep, has not slept since september, does not have the physical ability to fall asleep or stay asleep. She cannot sleep for more than 5-10 minutes at a time). On an unknown date, the patient experienced APALLIC SYNDROME (vegetative state) (seriousness criterion medically significant), HALLUCINATION (hallucinating) (seriousness criterion medically significant), ILLNESS (got very sick), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (stopped doing house chores,  she wouldn't get out of bed, can't sit up on her own), MEMORY IMPAIRMENT (forgot to pay her bills, memory started lapsing.), BEDRIDDEN (completely bed ridden), SPEECH DISORDER (can't speak), DYSPHAGIA (can't swallow, fed through a PEG tub), PARAESTHESIA (feels like pins and needles through her body, like she is being electrocuted through electrical shock), PERSONALITY CHANGE (complete personality change), COGNITIVE DISORDER (cognitive), ABNORMAL BEHAVIOUR (behavioral), CONFUSIONAL STATE (confused), AGITATION (agitated), APATHY (apathetic) and FATIGUE (extremely fatigued). The patient was treated with CLONAZEPAM (KLONOPIN) at an unspecified dose and frequency; TRAZODONE at an unspecified dose and frequency; VITAMIN B COMPLEX at an unspecified dose and frequency; APIXABAN (ELIQUIS) for Clot blood, at an unspecified dose and frequency and Bed rest for Dysphagia. At the time of the report, APALLIC SYNDROME (vegetative state), HALLUCINATION (hallucinating), ILLNESS (got very sick), VISION BLURRED (right eye was blurry), DYSARTHRIA (speech was slurred), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (stopped doing house chores,  she wouldn't get out of bed, can't sit up on her own), MEMORY IMPAIRMENT (forgot to pay her bills, memory started lapsing.), BEDRIDDEN (completely bed ridden), SPEECH DISORDER (can't speak), DYSPHAGIA (can't swallow, fed through a PEG tub), PARAESTHESIA (feels like pins and needles through her body, like she is being electrocuted through electrical shock), INSOMNIA (cannot sleep, has not slept since september, does not have the physical ability to fall asleep or stay asleep. She cannot sleep for more than 5-10 minutes at a time), PERSONALITY CHANGE (complete personality change), COGNITIVE DISORDER (cognitive), ABNORMAL BEHAVIOUR (behavioral), CONFUSIONAL STATE (confused), AGITATION (agitated), APATHY (apathetic) and FATIGUE (extremely fatigued) outcome was unknown.            No medical history was reported.  Patient went from being completely healthy to being in a vegetative state. She got very sick before the booster came out. In July her right eye was blurry, but she did not think anything of it. As of holiday weekend everything took a drastic turn.  She was polar like a complete 180 of a person.  Company comment: This case concerns a 64-year-old female patient with unknown medical history who experienced serious unexpected APALLIC SYNDROME and HALLUCINATION among numerous non-serious events described above. The events occurred after the second dose of mRNA-1273 in an unknown temporal relationship. It was reported that the patient concomitantly used SERTRALINE, ALPRAZOLAM and ZOLPIDEM but indications are unknown. The reporter did not provide causality assessment. Concomitant use of above mentioned drugs remains confounding. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This case concerns a 64-year-old female patient with unknown medical history who experienced serious unexpected APALLIC SYNDROME and HALLUCINATION among numerous non-serious events described above. The events occurred after the second dose of mRNA-1273 in an unknown temporal relationship. It was reported that the patient concomitantly used SERTRALINE, ALPRAZOLAM and ZOLPIDEM but indications are unknown. The reporter did not provide causality assessment. Concomitant use of above mentioned drugs remains confounding. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.