This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient. A 56-year-old female patient received BNT162b2 (BNT162B2), on 05Apr2021 as dose 1, single (Lot number: EW0160) at the age of 55 years, in left arm for Covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: AUTOIMMUNE DISORDER (medically significant), outcome "unknown", described as "its autoimmune and if you do not remove it from bottom it is going to eat through your bone"; TOOTHACHE (non-serious), LOOSE TOOTH (non-serious), outcome "unknown" and all described as "I woke up and two of my teeth; extremely painful and they are loose; I could wiggle almost and they will fall out"; MALOCCLUSION (non-serious), outcome "unknown", described as "I have a over bite"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "I was freaked out"; HUNGER (non-serious), outcome "unknown", described as "I can not eat in public so I am always hungry"; TOOTH EXTRACTION (non-serious), outcome "unknown", described as "front teeth are so far gone that we are going to pull that"; CRYING (non-serious), outcome "unknown"; FATIGUE (non-serious), outcome "unknown", described as "I have had the Covid shot I have been completely drained and I don't feel the same"; TOOTH RESORPTION (non-serious), outcome "unknown", described as "told me that its called a reabsorption and its a autoimmune reaction"; FEAR (non-serious), outcome "unknown", described as "afraid"; GINGIVAL GRAFT (non-serious), outcome "unknown", described as "they are able to recovered the other tooth by doing a gum graft lift". The events "its autoimmune and if you do not remove it from bottom it is going to eat through your bone", "I woke up and two of my teeth; extremely painful and they are loose; I could wiggle almost and they will fall out", "front teeth are so far gone that we are going to pull that", "told me that its called a reabsorption and its a autoimmune reaction" and "they are able to recovered the other tooth by doing a gum graft lift" required physician office visit. The patient underwent the following laboratory tests and procedures: Blood test: (unspecified date) Unknown result, notes: No, I have a blood work done every year and I have done last week; (Apr2022) Unknown result, notes: No, I have a blood work done every year and I have done last week; Scan: (unspecified date) Unknown result, notes: I have like 306 scan probably 8 10 times like it took one month. Therapeutic measures were taken as a result of autoimmune disorder, toothache, loose tooth, tooth extraction, tooth resorption, gingival graft. The patient stated she was having reaction after the Covid Pfizer shot then a couple of days woke up in morning and had two of her teeth, teeth number 9 and 11 are extremely painful and they are loose like a little kid like as if they would fall out of my head like and she could wiggle almost and they will fall out. She knew regarding a dent, and they told that its called a reabsorption and its a autoimmune reaction and they do not know what it is caused from and they asked if he had any trauma to mouth. She had a over bite, those 2 teeth do not touch any of my teeth. just do not touch anything, no clots in mouth nothing like that no problems with them before and so they sent to Dr. They said it is autoimmune this is not a bacterial thing it is nothing like that, its autoimmune and if do not remove it from bottom it is going to eat through your bone. And they say your front teeth are so far gone that we are going to pull that which she had done that is why have not called you because she was so upset about this all thing it made her cry. It happened within very short time after my first vaccine, she was so afraid cannot recall in details, she was freaked out went to see 4 specialist, they all said, to get a new front tooth and they are able to recovered the other tooth by doing a gum graft lift and pull it out and take all the like treated with medication probably 'Demerol', She don't know but doing it all see relived but whatever in the teeth, don't know what they did but they clean it out they said it is auto immune related it is not viral no bacterial or whatever, they called back and said, he had like 306 scan probably 8 10 times like it took one month, almost and finally broke out and have them pull tooth, front tooth, front upper tooth number 9 and went to 4 specialist, so they have bone graft pulled her front tooth do the bone graft and still have no front tooth and follow the routine and she was in sales and you can hear my speech and it was like cannot eat in public, just got back from sales meeting and cannot eat in public so always hungry. Blood work done every year and have done last week. Now since have had the Covid shot had been completely drained and don't feel the same. Patient has been taking because of bone graft in mouth and because of bone have been taking Calcium. When confirmed that Calcium is taken as a treatment of the side effect, Patient stated, "Not 'post side effects for after they pulled front tooth and they did a bone graft in front tooth hole and they said calcium would help that bone adhere to bone. But not doing it as much as she don't always remember every day".