With 1st dose arm was a little sore/felt a twinge at the injection site; This is a spontaneous report from a Pfizer-sponsored program from a contactable consumer (patient). A 63-years-old female patient received first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection, Lot Number: Unknown), via an unspecified route on 25Jan2021 at 12:00 (at the age of 63-years) as dose 1, single for covid-19 immunisation. The patient medical history included Arthritis, racing heart, blood pressure, thyroid from an unknown date and unknown if ongoing. The patient concomitant medications included ibuprofen (MOTRIN) 400 mg, 1x/day for arthritis, metoprolol succinate (TOPROL) for racing heart from an unknown date and unknown if ongoing. The patient previously received tetanus shot and Flu shot experienced injection site pain. On unspecified date, the patient experienced with 1st dose arm was a little sore and felt a twinge at the injection site. She was trying to stayed calm. She was proud to said she had been 64 on her birthday. On 25Jan2021 she had first dosed. She was supposed to got her second dosed on 15Feb2021. She was so excited. The nurse said she may felt nothing, but if she needed it caller could took tylenol or MOTRIN. With the first shot she had not felt anything. She got it at 12:00pm. Her husband felt a lot. She thought they hit a nerve in his shoulder. She had kind of thin arms. At 2am she felt a twinge at the injection site and she was so happy. Yesterday when she got it the nurse said you may not felt anything or you may needed motrin or tylenol. The nurse said that caller may felt more than after the first one liked a headache or muscle aches. Everyone was emailing about getting the vaccine. A friend said not to took any analgesic because it completely eradicates the vaccine. Every morning caller took toprol for her racing heart, two blood pressure pills, and motrin for arthritis. She took two of the 200mg over the countered motrin. Before she got the vaccines they asked if she had any other vaccines and if she had covid testing. No one ever asked if she take two motrin. When she got this texted she flipped out. Did that mean the vaccines had not worked? she got so nervous. She was calling because she was so excited that she was done. This time she got it at 12:00 in the afternoon and at 9:00pm she felt pain at the injection site. It was painful when she touches her armed. She had a little dull headache. She was scared that it had not worked. They scared her and they made her felt that because she take the motrin before the shot it would not worked. She took the motrin at 9am with her thyroid and blood pressure medication. It was three hours before she got the shot. Her husband started researching it and it said to continued mediations prescribed though it could effect the glands. She was scared that it had not worked. She doesn't understand why she had not read anything that said not to took motrin. That was what was so confusing. She could had just not taken it. She was very upset. Patient also experienced "slightest dull Headache, over my forehead and over my eyes. Feels a little fuzzy, feels a little off, slightly chillier than i usually feel, a bit cold. Caller says, injection site pain is like tetanus shot, tetanus shots feel worse than a flu shot. Caller says the vaccination provider told her that side effects could be a little worse after the 2nd dose and was told by the nurse to take Tylenol or Motrin if you have side effects. Caller says, I'm petrified that my vaccine didn't work, because she took her daily Motrin before the vaccine. She takes medication for thyroid, and fast heart rate (Toprol), and 2 over the counter Motrin for arthritis. The outcome of the event was unknown.  Information about lot/batch number has been requested.  Follow-up (14May2021): Follow-up attempts completed. No further information expected.