Jaw was excessively swollen/noticed a lump on the right side of the jaw/i had hard lumps on my jaw,swollen face and neck; Couldn't able to open the jaw for 2 days/limited jaw movement; Jaw was painful; Sweats; Feeling hot; No Appetite; Swollen neck; Chills; Fever of little above 104F; Body aches; Fatigue; Headache; This spontaneous case was reported by a consumer and describes the occurrence of SWELLING FACE (Jaw was excessively swollen/noticed a lump on the right side of the jaw/i had hard lumps on my jaw,swollen face and neck), TRISMUS (Couldn't able to open the jaw for 2 days/limited jaw movement), PAIN IN JAW (Jaw was painful), HYPERHIDROSIS (Sweats) and FEELING HOT (Feeling hot) in a 54-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 041B21A and 045A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history information was reported.  Concomitant products included QUINAPRIL from 02-Jan-2001 to an unknown date for Blood pressure, CENTRUM SILVER +50 from 01-Jan-2015 to an unknown date, ASCORBIC ACID, ROSA CANINA FRUIT (VITAMIN C & ROSEHIP) from 01-Jan-2018 to an unknown date and CLOZAPINE for an unknown indication.   On 22-Mar-2021 at 5:40 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Apr-2021 at 5:40 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 20-Apr-2021, the patient experienced SWELLING FACE (Jaw was excessively swollen/noticed a lump on the right side of the jaw/i had hard lumps on my jaw,swollen face and neck), TRISMUS (Couldn't able to open the jaw for 2 days/limited jaw movement), PAIN IN JAW (Jaw was painful), PYREXIA (Fever of little above 104F) and HEADACHE (Headache). 20-Apr-2021, the patient experienced HYPERHIDROSIS (Sweats), FEELING HOT (Feeling hot), DECREASED APPETITE (No Appetite), SWELLING (Swollen neck), CHILLS (Chills), MYALGIA (Body aches) and FATIGUE (Fatigue). The patient was treated with ACETAMINOPHEN for Pain, at an unspecified dose and frequency; AMOXICILLIN for Symptomatic treatment, at a dose of 500 mg; CLINDAMYCIN ongoing since an unknown date for Symptomatic treatment, at a dose of 300 mg and SULFAMETHOXAZOLE, TRIMETHOPRIM (SULFAMETHOXAZOLE AND TRIMETHOPRIM) for Symptomatic treatment, at a dose of 850/160 milligram. On 21-Jun-2021, SWELLING FACE (Jaw was excessively swollen/noticed a lump on the right side of the jaw/i had hard lumps on my jaw,swollen face and neck), TRISMUS (Couldn't able to open the jaw for 2 days/limited jaw movement), PAIN IN JAW (Jaw was painful), HYPERHIDROSIS (Sweats), FEELING HOT (Feeling hot), SWELLING (Swollen neck), CHILLS (Chills), PYREXIA (Fever of little above 104F), MYALGIA (Body aches), FATIGUE (Fatigue) and HEADACHE (Headache) had resolved with sequelae. At the time of the report, DECREASED APPETITE (No Appetite) had resolved with sequelae.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 20-Apr-2021, Body temperature: 104.5 (High) 104.5. On 21-Apr-2021, Body temperature: 100 (High) 100. On 04-May-2021, Computerised tomogram: inconclusive (Inconclusive) Patient went to near by ER and underwent CAT scan with and without contrast..         Patient went to ENT specialist on10MAY2021 as he was not getting better & was prescribed Sulfamethoxazole-Trimethoprim 850/160 mg for the jaw pain. Patient was on antibiotic for 5 weeks. He went to ENT multiple times, had CT scan , went to Dentist& Endodontist for imaging. Patient still had lump on jaw, much smaller & slowly dissipating at the time of reporting.   This case was linked to MOD-2021-177119 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 23-Jun-2021: Additional information received: Updated patient details and events information.