really bad reaction / severe reaction; made my skin go crazy; half of my body was covered in welts; minor, then a moderate, and a severe rash for each  dose; This spontaneous case was reported by a patient and describes the occurrence of IMMUNISATION REACTION (really bad reaction / severe reaction), SKIN DISORDER (made my skin go crazy), URTICARIA (half of my body was covered in welts) and RASH (minor, then a moderate, and a severe rash for each  dose) in a 65-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 037A22B) for COVID-19 vaccination.     Previously administered products included for Drug use for unknown indication: J&J vaccine (Dose Number: 1st booster, Lot number: 212A21A and Dose: unknown) on 23-Oct-2021. Past adverse reactions to the above products included No adverse event with J&J vaccine. Concurrent medical conditions included Drug allergy (allergy to codein) and Prostate cancer (started coming back in 2000) since 1998. Concomitant products included RELUGOLIX (ORGOVYX), BICALUTAMIDE (CASODEX), DUTASTERIDE (AVODART) and BISOPROLOL for an unknown indication.   On 25-May-2022, the patient received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In May 2022, the patient experienced IMMUNISATION REACTION (really bad reaction / severe reaction), SKIN DISORDER (made my skin go crazy), URTICARIA (half of my body was covered in welts) and RASH (minor, then a moderate, and a severe rash for each  dose). The patient was treated with TRIAMCINOLONE at a dose of UNK, 0.1%; PREDNISONE at a dose of UNK, pills and CORTISONE at an unspecified dose and frequency. In 2022, IMMUNISATION REACTION (really bad reaction / severe reaction) and SKIN DISORDER (made my skin go crazy) had resolved. In September 2022, URTICARIA (half of my body was covered in welts) and RASH (minor, then a moderate, and a severe rash for each  dose) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In February 2022, SARS-CoV-2 test: (Positive) Positive.  Caller mentioned he got 2 primary and booster shots, but never had the Pfizer COVID-19 Vaccine. Caller got the Moderna, then the J & J and the Moderna again; reported having a rash for each 10-12 days after the shot. Caller said he got a minor, then a moderate, and a severe rash for each dose and was given a cortisone injection that lasted 5-6 weeks.  After the Moderna vaccine, the patient had a really bad reaction. Half of patients body was covered in welts. That lasted 4-5 weeks to go away, and the patient had to get a Cortisone shot.  It seemed to the patient that the reaction got worse and worse all three times. The patient was trying to keep boosted as the patient is a cancer patient, but he is fearful of getting Moderna vaccine. The patient was trying to figure out if the patient was allergic to some ingredient in the vaccine or mRNA technology. The patient reported that the steroid creams made his skin go crazy and did not really help him. The patient was strongly encouraged to speak with a healthcare provider. It was reported that patient had minor, moderate and sever rash for each dose.  The patient received Flu vaccine in Sep 2022. The patient visited dermatologist visit after booster dose. The patient never experienced similar event in the past before getting Moderna doses.  The patient was prescribed with a cream (triamcinolone ointment 0.1 percent) after the second dose. The patient was put on prednisone pills after the booster. When that did not work, he got a cortisone shot from the dermatologist office.   This case was linked to MOD-2022-648653, MOD-2021-339509.   Most recent FOLLOW-UP information incorporated above includes: On 22-Sep-2022: Live significant follow up : narrative and event updated