Immobile; She needed physical therapy and rehab and it didn't help, she gets physical therapy and rehab in the nursing some, but the amount is limited she is getting worse; continues to get weak; forgot how to walk; lack of mobility; pain at the injection site; Fatigue; severe headaches; neurological symptoms; confused, can't keep thoughts in their heads; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP), Program ID.  A 70-year-old female patient (unknown if pregnant) received BNT162b2 (BNT162B2), on 24Apr2021 as dose 2, single (Lot number: ER8736) at the age of 68 years for covid-19 immunisation. The patient's relevant medical history included: "Lung cancer" (unspecified if ongoing), notes: Medical Conditions: Cancer: she has lung Cancer; "brain cancer" (unspecified if ongoing), notes: Medical Conditions: Cancer: she has brain cancer; "he was diagnosed" (unspecified if ongoing), notes: he was diagnosed around Apr2019; "Parkinson's" (unspecified if ongoing), notes: She saw an neurologist and that doctor said it was Parkinson's. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Dose #1: , Date: 31Mar2021 , Lot: ER8733, Expiry: unknown , NDC: unknown), administration date: 31Mar2021, when the patient was 68-year-old, for COVID-19 immunization, reaction(s): "pain at the injection site", "Fatigue", "severe headaches", "confused, can't keep thoughts in their heads", "lack of mobility", "forgot how to walk", "continues to get weak".  The following information was reported: IMMOBILE (medically significant), outcome "unknown"; CONDITION AGGRAVATED (medically significant), outcome "unknown", described as "She needed physical therapy and rehab and it didn't help, she gets physical therapy and rehab in the nursing some, but the amount is limited she is getting worse"; ASTHENIA (non-serious), outcome "not recovered", described as "continues to get weak"; GAIT INABILITY (non-serious), outcome "unknown", described as "forgot how to walk"; MOBILITY DECREASED (non-serious), outcome "unknown", described as "lack of mobility"; VACCINATION SITE PAIN (non-serious), outcome "unknown", described as "pain at the injection site"; FATIGUE (non-serious), outcome "unknown"; HEADACHE (non-serious), outcome "unknown", described as "severe headaches"; NEUROLOGICAL SYMPTOM (non-serious), outcome "unknown", described as "neurological symptoms"; CONFUSIONAL STATE (non-serious), outcome "unknown", described as "confused, can't keep thoughts in their heads". Therapeutic measures were taken as a result of immobile, gait inability, mobility decreased.  Clinical Course: Agent stated she had a caller on the line who was wanting to report possible side effects on his mother that have continued for 1.5 years. Also mentioned that his brother-in-law has identical symptoms as his mother as well as 4 other people in the area of (State name). Caller confirms above information and adds it was not just his mother but it was brought to his attention that his brother in law and 2 other friends have identical symptoms too. It was reported that patient was on Medicaid or Medicare through medical mutual now she was in a nursing home because of her severe mobility, and he could not help her. she was starting to get weak and progressively worse. Her HCP has changed a lot prior to Covid she was battling cancer and had all her treatments done before Covid started and was with a regular doctor and now she has one through the system at clinic. she sees a doctor in the nursing home. caller does not know when it started states she was getting weak and he thought it was from the cancer. now he has seen a couple of customers and friends who have identical symptoms. she went and got the shots when she was able to and she continues to decline. She couldn't walk and just continues to decline, she couldn't get out of bed. The cancer doctor started to yell at her and said they didn't give her anything to make her be like this. Attempted clarification if there was a booster dose, caller states not that he knows of unless she got a dose at the facility she lives at now that he was not aware of. Medical Conditions was reported as  Cancer. she has lung and brain cancer combined and got it a year prior. she was diagnosed around Apr2019. Her treatment started Sep2019 and was done in Dec2019.She saw an neurologist and that doctor said it was Parkinson's, caller states there was no bloodline of that anywhere. She has 5 older sisters and they don't have anything like that. She was the baby. Parkinson's was hereditary. Caller states he was blaming this all on the cancer and when he started hearing about other people how identical they are it is frightening. They have no relation at all and have the same symptoms.it was reported that patient could not remember if she was 68 or 69, she just turned 70.it.Vaccination Facility Type was reported as It was school at a mass injection area available for her age group. History of all previous immunization was reported as n/a. information about Additional Vaccines Administered on Same Date was reported as: patient usually gets the pneumonia and flu shots, but patient  didn't get them at that time. Patient did not have Prior Vaccinations (within 4 weeks). Patient did not have AE(s) following prior vaccinations: no AE did not results into Emergency Room and Physician Office. caller then adds that she had initial pain at the injection site like everyone else and the fatigue got real bad and turned into the gait and forgetting how to walk. Patient's Medical History was reported as no. Relevant Tests was reported as .no, blood work always looks good. Other Products was reported as No.  Follow-up attempts are completed. No further information is expected.