I have with traumatic brain injury; she was not feeling well; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A female patient received BNT162b2 (BNT162B2), on 03Mar2021 as dose 2, single (Lot number: EN5318) for covid-19 immunisation. The patient's relevant medical history included: "chronic health issues" (unspecified if ongoing), notes: she had a lot of chronic health issues(History). The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (DOSE 1, SINGLE , Product name- Pfizer COVID-19 vaccine , Batch/lot number: EN5318), administration date: 10Feb2021, for Covid-19 immunization. The following information was reported: CRANIOCEREBRAL INJURY (medically significant), outcome "unknown", described as "I have with traumatic brain injury"; MALAISE (non-serious), outcome "unknown", described as "she was not feeling well".  Clinical information: Call was transferred from Pfizer. Transferring agent stated, She was calling about the Pfizer COVID-19 vaccine so she said that she got her first two doses. For the first dose and the second dose of vaccine last year that was Mar2021. She did not received another vaccination for booster or a first booster. Because she was not feeling well at that time and she have a lot of chronic health issues(History). So she said right now she can handle this next variant of vaccine. But she wants to know if she can still get it, since it is been a year or she got her first two doses of the vaccine. She also mentioned that she survive hospitals and medical facilities and her last time, she did not mean very isolated in her life style. When paraphrased the details Consumer stated, Okay yes, and she had with traumatic brain injury, have to speak little slower for her. Because she had trouble with speed and accent. Consumer stated, No, what she wanted to speak to somebody regarding, she had doses in Feb and Mar of 2021 last year. She had the first and second dose of Pfizer she had never had a booster neither one and so I am behind on my vaccination but amazingly she was not was in a lot of high traffic areas and hospitals and medical facilities etc. and she never want had any COVID response at this point in time her question to you is do she need to pursue the booster or should wait to see if the vaccination comes out for the latest strain and what value is the booster going to be provide for me. Consumer was informed about the Pfizer drug safety role as well as Pfizer medical Information Department. In response to that Consumer further stated, No she was not against vaccination she was truly into them. But she was so busy during this other medic problem. she did not give a chance to get it done and may be the question in order is after all this time if riding all these environment and in the currently if the living facility that had a COVID restriction going on well she was not down and she was still did not get exposed and like how did go through all this with no booster and what did the booster going to do for me. What my immune system has been already done for me.   No follow-up attempts are possible. No further information is expected.