a big angry red/site of the vaccination (upper right dominant arm) started to turn very red; inflammation in the area of the injection site down to the elbow; Site of the vaccination (upper right dominant arm) started to turn very red and itchy in big area of the arm; Swelling in the area of the injection site down to the elbow; Discomfort; Tenderness; This spontaneous case was reported by a health care professional and describes the occurrence of DISCOMFORT (Discomfort), TENDERNESS (Tenderness), VACCINATION SITE INFLAMMATION (inflammation in the area of the injection site down to the elbow), VACCINATION SITE PRURITUS (Site of the vaccination (upper right dominant arm) started to turn very red and itchy in big area of the arm) and VACCINATION SITE SWELLING (Swelling in the area of the injection site down to the elbow) in an 85-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 035C21A, 016M20A and 012L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hypertension.   On 14-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 11-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Oct-2021, the patient experienced DISCOMFORT (Discomfort) and TENDERNESS (Tenderness). On 30-Oct-2021, the patient experienced VACCINATION SITE INFLAMMATION (inflammation in the area of the injection site down to the elbow), VACCINATION SITE PRURITUS (Site of the vaccination (upper right dominant arm) started to turn very red and itchy in big area of the arm) and VACCINATION SITE SWELLING (Swelling in the area of the injection site down to the elbow). On 31-Oct-2021, the patient experienced VACCINATION SITE ERYTHEMA (a big angry red/site of the vaccination (upper right dominant arm) started to turn very red). The patient was treated with TRIAMCINOLONE from 01-Nov-2021 to 04-Nov-2021 for Redness, at an unspecified dose and frequency. At the time of the report, DISCOMFORT (Discomfort), TENDERNESS (Tenderness), VACCINATION SITE INFLAMMATION (inflammation in the area of the injection site down to the elbow), VACCINATION SITE PRURITUS (Site of the vaccination (upper right dominant arm) started to turn very red and itchy in big area of the arm) and VACCINATION SITE SWELLING (Swelling in the area of the injection site down to the elbow) outcome was unknown and VACCINATION SITE ERYTHEMA (a big angry red/site of the vaccination (upper right dominant arm) started to turn very red) was resolving.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No Concomitant medications were reported.  At the time of reactions patient was not able to speak to her dermatologist, but she had triamcinolone 1 percentage cream from a previous arm problem and applied. Then she saw a dermatologist, and they told her to continue using the cream.   This case was linked to MOD-2021-015455, MOD-2021-093396 (Patient Link).