ultrasound; Lymph node bumps at the left side of the neck; This case was initially received via an unknown source (no reference has been entered for a health authority or license partner) on 08-Mar-2021. The most recent information was received on 18-May-2021 and was forwarded to Moderna on 19-May-2021.    This spontaneous case was reported by a consumer and describes the occurrence of ULTRASOUND SCAN ABNORMAL (ultrasound) and LYMPHADENOPATHY (Lymph node bumps at the left side of the neck) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 042L20A) for COVID-19 vaccination.     Concurrent medical conditions included Muscle spasm, Emphysema, Hypertension, Anxiety, Diabetes mellitus, Incontinence, Acid reflux (esophageal), Depression, COPD, Thyroid disorder NOS, Liver disorder (autoimmune liver disease), Allergy, Sleep apnea and Pain. Concomitant products included OMEPRAZOLE (PROTONIX [OMEPRAZOLE]) for Acid reflux (esophageal), MOMETASONE FUROATE (FLONASE [MOMETASONE FUROATE]) and CETIRIZINE HYDROCHLORIDE (ZYRTEC ALLERGY) for Allergy, ESCITALOPRAM OXALATE (LEXAPRO) and HYDROXYZINE for Anxiety, MONTELUKAST SODIUM (SINGULAIR) for Breathing difficult, FLUTICASONE (BRISOVENT DISKUS) for COPD and Emphysema, ATORVASTATIN CALCIUM (LIPITOR) for Cholesterol, BUPROPION HYDROCHLORIDE (WELLBUTRIN) for Depression, METFORMIN for Diabetes mellitus, ALBUTEROL [SALBUTAMOL] for Emphysema, LOSARTAN and AMLODIPINE BESILATE (NORVASC) for Hypertension, OXYBUTYNIN for Incontinence, URSODIOL for Liver disorder, BACLOFEN for Muscle spasm, IBUPROFEN and PARACETAMOL (TYLENOL) for Pain, MELATONIN for Sleep difficult, MULTI VIT, CALCIUM CARBONATE, COLECALCIFEROL, VITAMIN K NOS (CITRACAL [CALCIUM CARBONATE;COLECALCIFEROL;VITAMIN K NOS]), BIOTIN and VITAMIN D3 for Supplementation therapy, LEVOTHYROXINE for Thyroid disorder NOS, ACETYLSALICYLIC ACID (ASPIRIN 81) for an unknown indication.   On 09-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 09-Feb-2021, the patient experienced LYMPHADENOPATHY (Lymph node bumps at the left side of the neck). On 05-Mar-2021, the patient experienced ULTRASOUND SCAN ABNORMAL (ultrasound). At the time of the report, ULTRASOUND SCAN ABNORMAL (ultrasound) and LYMPHADENOPATHY (Lymph node bumps at the left side of the neck) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 05-Mar-2021, Ultrasound scan: lymph node bumps swollen lymph nodes..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No treatment was provided.   Most recent FOLLOW-UP information incorporated above includes: On 16-Apr-2021: Permission to F/U with physician.second dose was added.secondary reporter details was updated. On 18-May-2021: Non-significant follow-up appended to AER: update info about PCP.; Reporter's Comments: Very limited information regarding this event/s has been provided at this time.  Further information has been requested.