Symptoms progressively got worse; right and left hand seemed to be drawing in and he could not grip anything; could not walk good, he had been crying; hurting near groin area; Hurting near hip area/Still hurting in in hip area; Patient is also hardly eating now; partial paralysis; This spontaneous case was reported by a consumer and describes the occurrence of CONDITION AGGRAVATED (Symptoms progressively got worse), GRIP STRENGTH DECREASED (right and left hand seemed to be drawing in and he could not grip anything), GAIT DISTURBANCE (could not walk good, he had been crying), GROIN PAIN (hurting near groin area), ARTHRALGIA (Hurting near hip area/Still hurting in in hip area), FEEDING DISORDER (Patient is also hardly eating now) and PARALYSIS (partial paralysis) in a 22-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Autism (non-verbal autistic).    On 03-Sep-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced CONDITION AGGRAVATED (Symptoms progressively got worse) (seriousness criteria hospitalization and disability), GRIP STRENGTH DECREASED (right and left hand seemed to be drawing in and he could not grip anything) (seriousness criteria hospitalization and disability), GAIT DISTURBANCE (could not walk good, he had been crying) (seriousness criterion hospitalization), GROIN PAIN (hurting near groin area) (seriousness criterion hospitalization), ARTHRALGIA (Hurting near hip area/Still hurting in in hip area) (seriousness criterion hospitalization), FEEDING DISORDER (Patient is also hardly eating now) (seriousness criterion hospitalization) and PARALYSIS (partial paralysis) (seriousness criteria disability and medically significant). The patient was hospitalized from 20-Sep-2021 to 21-Sep-2021 due to ARTHRALGIA, CONDITION AGGRAVATED, FEEDING DISORDER, GAIT DISTURBANCE, GRIP STRENGTH DECREASED and GROIN PAIN. At the time of the report, CONDITION AGGRAVATED (Symptoms progressively got worse), GRIP STRENGTH DECREASED (right and left hand seemed to be drawing in and he could not grip anything), GAIT DISTURBANCE (could not walk good, he had been crying), GROIN PAIN (hurting near groin area), ARTHRALGIA (Hurting near hip area/Still hurting in in hip area), FEEDING DISORDER (Patient is also hardly eating now) and PARALYSIS (partial paralysis) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Computerised tomogram: normal (normal) Normal. On an unknown date, Ultrasound scan: normal (normal) Normal ultrasound on both his legs.         Concomitant medications were not provided.   The patient's father had to get a wheelchair for him on 28-Sep-2021.   Treatment information was not provided.  Company comment: This case concerns a 22-year-old, female patient with no previous relevant medical history, who experienced the unexpected events of Condition aggravated, grip strength decreased, gait disturbance, groin pain, arthralgia, feeding disorder, and paralysis. The events occurred 17 days after the first dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was not applicable since only information about the first dose was disclosed. The benefit-risk relationship of mRNA-1273 (Moderna COVID-19 Vaccine) is not affected by this report.   This case was linked to MOD-2021-336017 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 30-Sep-2021: Follow up appended contains additional event partial paralysis.; Sender's Comments: This case concerns a 22-year-old, female patient with no previous relevant medical history, who experienced the unexpected events of Condition aggravated, grip strength decreased, gait disturbance, groin pain, arthralgia, feeding disorder, and paralysis. The events occurred 17 days after the first dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was not applicable since only information about the first dose was disclosed. The benefit-risk relationship of mRNA-1273 (Moderna COVID-19 Vaccine) is not affected by this report.