needed a spoon to eat my lunch/can't function to eat; difficulty using dominant hand to write checks/Symptoms Not relieved by hand warmers, nor Aleve.; side effects in dominant hand of the arm that she received the vaccine.; swelling and numbness on 3 fingers of dominant hand/the thumb, pointer and middle fingers are swollen,; numbness  on 2nd and third section of the 3 fingers/swelling and numbness on 3 fingers of dominant hand/numbness in tips/Dropping things because of the numbness/Numb fingers for 5 days; This spontaneous case was reported by a patient and describes the occurrence of VACCINATION SITE REACTION (side effects in dominant hand of the arm that she received the vaccine.), PERIPHERAL SWELLING (swelling and numbness on 3 fingers of dominant hand/the thumb, pointer and middle fingers are swollen,), HYPOAESTHESIA (numbness  on 2nd and third section of the 3 fingers/swelling and numbness on 3 fingers of dominant hand/numbness in tips/Dropping things because of the numbness/Numb fingers for 5 days), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (needed a spoon to eat my lunch/can't function to eat) and MUSCULAR WEAKNESS (difficulty using dominant hand to write checks/Symptoms Not relieved by hand warmers, nor Aleve.) in an 83-year-old female patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. AS7148B) for COVID-19 vaccination.     Concurrent medical conditions included Penicillin allergy and Sulfonamide allergy.    On 28-Sep-2022, the patient received fifth dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Intramuscular) 1 dosage form. On 13-Oct-2022, the patient experienced VACCINATION SITE REACTION (side effects in dominant hand of the arm that she received the vaccine.), PERIPHERAL SWELLING (swelling and numbness on 3 fingers of dominant hand/the thumb, pointer and middle fingers are swollen,) and HYPOAESTHESIA (numbness  on 2nd and third section of the 3 fingers/swelling and numbness on 3 fingers of dominant hand/numbness in tips/Dropping things because of the numbness/Numb fingers for 5 days). On 16-Oct-2022, the patient experienced LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (needed a spoon to eat my lunch/can't function to eat). 16-Oct-2022, the patient experienced MUSCULAR WEAKNESS (difficulty using dominant hand to write checks/Symptoms Not relieved by hand warmers, nor Aleve.). The patient was treated with NAPROXEN SODIUM (ALEVE) at an unspecified dose and frequency. At the time of the report, VACCINATION SITE REACTION (side effects in dominant hand of the arm that she received the vaccine.), PERIPHERAL SWELLING (swelling and numbness on 3 fingers of dominant hand/the thumb, pointer and middle fingers are swollen,), HYPOAESTHESIA (numbness  on 2nd and third section of the 3 fingers/swelling and numbness on 3 fingers of dominant hand/numbness in tips/Dropping things because of the numbness/Numb fingers for 5 days), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (needed a spoon to eat my lunch/can't function to eat) and MUSCULAR WEAKNESS (difficulty using dominant hand to write checks/Symptoms Not relieved by hand warmers, nor Aleve.) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, SARS-CoV-2 test: (Negative) Negative.         No Medical history relating to mentioned AE and both acute and chronic illnesses at the time of vaccination.  No other vaccines given within 1 month prior to Moderna COVID-19 vaccine. No concomitant drug was reported. On 11-Jan-2021, Patient received dose 1 with Lot number 012L20A and expiration date was reported as 06-Jul-2021. On 11-Feb-2021, Patient received dose 2 with Lot number 012M20A and expiration date was reported as 20-Jul-2021. On 31-Oct-2021, Patient received first booster with Lot number 012F21A and expiration date was not reported. On 01-Apr-2022, patient received second booster with Lot number 033C21-2A  and expiration date was not reported. Symptoms not relieved by hand warmers, nor Aleve.