severe allergic reactions; strep throat; joint pain; Pain; that's how foggy his brain is with what's going on his thinking is not straight from the pain; This is a spontaneous report from a contactable consumer (patient). A 59-year-old male patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/lot number: ER8727, Expiration Date: Jul2021) via an unspecified route of administration on 19Mar2021 at 14:30 (at 59-year-old) at single dose in upper left arm for COVID-19 immunization. Medical history included depression, anxiety, high blood pressure, high cholesterol, and high triglycerides. Concomitant medication(s) included hydrochlorothiazide/ lisinopril (LISINOPRIL/HCTZ) hypertension; citalopram; trazodone for sleep disorder; zolpidem for sleep disorder; simvastatin for blood cholesterol; alprazolam for anxiety (doctors said high dose which he needed to be stable, at least 7 years ago); and fenofibrate for blood triglycerides increased. No prior vaccinations within 4 weeks. E-transmitting possible duplicate AE as caller stated they already reported AE to previous agent. He had near all the side effects listed as well as severe allergic reactions listed. He hasn't been able to get out of the house since, felt like he had the flu. He has had the symptoms since; tiredness, headache, pain, terrible chills every day, joint pain, nausea, he was a hearty eater and he did not have a good appetite/ no appetite; he felt unwell, completely unwell, a sick feeling and it's pronounced; and particularly swollen lymph nodes, difficulty breathing at times, definite swelling of face and throat, dizziness and weakness. Caller provided these all started 2 weeks after he got the shot. Started on Saturday, 03Apr2021, and same thing happened everyday (going on). He called the weekend and after a couple weeks he called, the on call doctor and after his second call he was ordered to get to a medical facility/ urgent care facility (went to the doctor and it wasn't his regular doctor) in the weekend of 11Apr2021 and he has one nearby and they ran a test for COVID and it was negative, also tested for strep throat positive. He was given amoxycillin 30 tablets, 500mg tablets to be taken 3 times a day for 10 days for the strep throat, although he has not had any symptoms of strep throat which for him it is pronounced and painful, he can swallow, has no pain, no cough, nothing, he has nothing. His soreness and everything here was exactly what was in the manual was what he has going on and nothing else, no mucous, nothing like that. Confined to his house, has no energy to do anything chills and hot flashes. He has been taking ibuprofen 800mg tablets with food, 1 in the morning and 1 in the evening and got some relief from the chills and symptoms but not totally and it was waning in it's effectiveness after the first 3-4 days. All his symptoms were persisting and they had worsened after he started getting then for he guesses 4-5 days and then they kind of leveled as bad as they are now and haven't tailed off. He was ordered not to take the 2nd dose until he finishes all the amoxicillin and was told quite sternly not to get the 2nd dose until he finishes it. He has 12 pills left so next week sometime Tuesday or Wednesday and his concern was he finished that medicine and feels he would still have these side effects and doesn't know if he would build up immunity and maybe the 2nd shot won't be as bad. The nurse practitioner who worked with him at the urgent medical care place said the 2nd shot is a doozy and not to mix it with Amoxicillin as it might have a bad effect on the effectiveness of the strep throat. States he has had strep before and doesn't feel like that at all and nothing is wrong with his voice, throat or upper respiratory at all. He is supposed to get the 2nd shot tomorrow (16Apr2021), he was scheduled. He was afraid to do it as he hears it's worse than the 1st one and he is already relegated to his house and has to order in and not risk driving that's how foggy his brain was with what's going on his thinking is not straight from the pain. The outcomes of the events were unknown.