Facial swelling; Eye swelling; Aches and pains; Left ankle was swollen; This is spontaneous report from a contactable consumer (patient mother). A 47-year-old female patient had received age received BNT162b2 (PFIZER BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Lot number- UNKNOWN) via an unspecified route of administration in arm left on 03Feb2021 as dose 2, single for COVID-19 immunization (at an age of 47 years); botulinum toxin type a (BOTOX), via an unspecified route of administration from 15Feb2021 (Batch/Lot number was not reported) to 15Feb2021, at unspecified dose for an unspecified indication. Medical history included, drug hypersensitivity (sensitive to drugs), from an unknown date and unknown if ongoing. The patient's concomitant medications were not reported. The patient had previously took BNT162b2 (PFIZER BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Lot number- UNKNOWN) via an unspecified route of administration on Jan2021 as dose number 1, single for COVID-19 immunization and had no problem with dose 1 and also took flu shot greater than 4 weeks prior to the Pfizer Vaccine. It was reported that reporter has been to so many HCPs right now including an internist and allergist and does not wish to provide this information at this time. States she would like information on this, and everything seems to say the Botox is only fillers, and the reported event is not the Botox and there have been so many HCPs and she would like more information on this or if this has been reported by others; states her daughter cannot be the only person in the world to experience this. States the patient first went back to the HCP that gave her the Botox injection and the symptom of facial swelling and also reported came out right away 2 days after she had the Botox injection and the HCP said it was not the Botox causing this and she went back to the HCP three times and he put the patient on Prednisone and the Prednisone did not really help the swelling and the facial swelling has been going on since Feb2021. States the facial swelling is better and now the patient has been on Prednisone and then went off of it and she thought the patient may have had side effects from the Prednisone itself because the patient is sensitive to drugs and then went on the Prednisone another time and off of the Prednisone and then did go on the Prednisone full time from the dermatologist in (withheld) and the Prednisone did not seem to help the patient that much. States the patient was then put on Doxycycline low dosage for a month and felt that her symptoms could be bacteria because Botox is a poison and could have bacteria and the patient is having pains all over going to different places in her body; states the pain is not really muscle weakness and she went to the HCP about that too. States she has more aches and pains in her wrists that hurt, and her legs hurt and there are weird sharp pains all over; states the pain got better quite a bit then she just had a bad day on last Friday which was a very bad day and she was very weak and was practically limping when she came home from work; states the patient saw the HCP on Saturday and was also getting her period too which could be a factor. Caller states she has no lot numbers, expiry dates, NDC numbers, or dosages for the Botox, Prednisone, or the Doxycycline to provide. States the patient got the 2nd dose of the Pfizer Vaccine on 03Feb2021 and the Botox shot was administered on 15Feb2021 so it was not even two weeks, and the caller thought the HCP should not have given the Botox to the patient and it was the first time the patient got the Botox injection into her face, forehead and the side of her eye which the caller feels the patient did not need. States the patient had swelling of her face within the first week after the Botox there was a big bump in the center of the patient's forehead and the HCP thought this was very unusual. States the patient's eyes started swelling big underneath her eyes and they told her that is going to go away; the dermatologist looked carefully and her whole face was swollen and noticed when her leg hurt her it looked like her ankle was swollen which was the left ankle and the Pfizer Vaccine 2nd dose was administered into her left arm. States the patient had no problem with the 1st dose of the Pfizer Vaccine and the 2nd one she went to work the next day and came home achy and stuff and then was ok and thinks she started getting the little weird pains just before the Botox injection which was maybe 10 days after; despite further attempts at clarification, the information is captured as stated by the caller. States the Doxycycline the patient took was 50mg and started it two days ago yesterday and after that finished a week or 6 days of Prednisone pack where you take Prednisone 6 pills the first day. States the Prednisone she was on for a couple of days and was getting worse pains in her leg and the caller's dog had problems with Prednisone, so the caller thought it maybe the Prednisone and the HCP said to stop the Prednisone. States another HCP gave the patient Prednisone also and told her to stop it at that time; states the last HCP gave her more Prednisone and the patient did finish that whole pack and the Prednisone did not seem to help the swelling. States the patient did have a flu shot quite a bit before the Pfizer Vaccine and she does not know the dates or lot number for the flu shot but it was greater than 4 weeks prior to the Pfizer Vaccine. States the swelling at this point has gone down and she still has the terrible aches as of this last Friday and the aches are probably as bad as they were at the beginning. On 17Feb2021 the patient had experienced swelling face, eye swelling, aches and pains, also her left ankle was swollen. Patient underwent lab test and procedures which had included blood test and diagnosed with normal values. On 17 feb2021 the patient underwent lab test and procedures which included WBC and diagnosed with 13. Therapeutic measures were taken with the AE and treatment were given with Prednisone and doxycycline. The clinical outcome of the events were not recovered and outcome of the event her left ankle was swollen was not recovered  Information on the lot/batch number has been requested