With both boosters he suffered skin infections that escalated into severe problems needing hospitalization; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID.  A 72-year-old male patient received BNT162b2 (BNT162B2), on 10Sep2022 as dose 4 (booster), single (Batch/Lot number: unknown) at the age of 72 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Autoimmune disease" (unspecified if ongoing); "Still's disease adult onset" (unspecified if ongoing), notes: Still's disease adult onset. The patient took concomitant medications. Vaccination history included: BNT162b2 (1st dose Pfizer COVID-19 Vaccine: Date Received: 05Mar2021., 1st and 2nd booster shots and ended up with a pretty severe skin infection), administration date: 05Mar2021, when the patient was 71-year-old, for COVID-19 immunization, reaction(s): "Skin infection"; BNT162b2 (2nd dose Pfizer COVID-19 Vaccine: Date Received: 26Mar2021., 1st and 2nd booster shots and ended up with a pretty severe skin infection), administration date: 26Mar2021, when the patient was 71-year-old, for COVID-19 Immunization, reaction(s): "Skin infection"; BNT162b2 (1st booster dose Pfizer COVID-19 Vaccine: Date Received: She is pretty sure his date was 04Sep2021.), administration date: 04Sep2021, when the patient was 72-year-old, for COVID-19 Immunization, reaction(s): "illness", "Skin infection"; Flu vaccines (one things talked about; doesn't have AE with flu vaccines and has, had those).   The following information was reported: SKIN INFECTION (hospitalization), outcome "unknown", described as "With both boosters he suffered skin infections that escalated into severe problems needing hospitalization".  Clinical information: Patient reported for her husband received the first two Covid shots and then boosters 04Sep2021 and 10Sep2022. He had skin infection. Patient had an autoimmune disease that makes him vulnerable to infection. Since injections a problem for him so reporter asked is there any alternate method to apply the booster. Reporter remember received her Polio vaccine on a sugar cube in the 1960s. Reporter subtype reported as caregiver. Patient had an autoimmune disease which makes him more susceptible to infections. He received the 1st and 2nd booster shots and ended up with a pretty severe skin infection and had to be hospitalized for treatment after injections. Reporter wanted to know if there was an altered way to receive the new Covid booster doses. With both boosters he suffered skin infections that escalated into severe problems needing hospitalization. Reporter reported that the Patient was not a doctor, but we dont believe it was the medicine itself and there had other injections which have caused him infection as well, was not just the booster. Reporter requests information for alternate dosage forms available for the Pfizer-BioNTech COVID-19 vaccine, Bivalent (Original and Omicron BA.4/BA.5) booster dose for 12 years of age and older and where she may find this information online. Second booster dose received on 10Sep22 (Saturday) was the bivalent booster. No alternate dosage forms were available they replied in response and booster dose for 12 years of age and older failed to find any information regarding alternate dosage forms available asides from injection. Please consult with your doctor or health care provider for further guidance. Reporter also requests information for alternate treatment options to protect patients from COVID-19 when they cannot tolerate the Pfizer-BioNTech COVID-19 vaccine booster dose for 12 years of age and older. Report was not related to a study or programme. Other product reported as yes. Reporter saying the booster doses that caused this event because her husband does suffer from those infections frequently. This booster dose was the Pfizer BioNTech COVID-19 Vaccine and previous booster dose was Pfizer as well. Agent was unable to confirm if Bivalent vaccine for most recent booster dose. Agent provided responses she had asked for and offered transfer to drug safety unit for report. She has to be off the phone at 3pm or in 20 minutes as she has another appointment. Infection occurred to patient after 24 hours of vaccine and hospital had to use intravenous antibiotics to take care of the infection. She is not certain if her husband recovered completely but did come home and then got very sick again and ended up in hospital for another 3 or 4 days. She doesn't know if medical personnel thought from first time was reason for his second hospitalization. Reporter had COVID and was not able to go to the hospital. They do not have her husband vaccination cards but she has her card and can tell dates as her and her husband received the first vaccines at the same time. Pfizer for all doses. On her card was hand written when she received the card but just noticed there has been stickers put over that so she is unable to see the dates. Her husband has an extensive list of medications and doesn't think she is at liberty to provide that information. Vaccine Administered at a Facility reported as no. No any emergency room visited. Patient currently in hospital with current infection. No any other vaccinations within four weeks prior to the first administration date of the suspect vaccine. For the stills disease has had a variety of drug therapies and at least one recall an skin infection with injection and possible with compromised immune system at least once. The patient situation has been going on for 10 years; worst drug ever took was advertised on tv a lot. Terrible for him but helps some people. No family medical history reported. Relevant Tests reported as None.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.