Hard time breathing; At night is up coughing; Fatigue/ tired and stayed in bed all day; Chills; Low grade fever; Something cuts off in her chest and neck area; This is a spontaneous report from a contactable consumer (patient, self-reporting). A 51-years-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Solution for injection, Lot number: EW0169 and expiration date: Aug2021), via an unspecified route of administration in arm left on 29Apr2021 at 12:30 (at the age of 51-years-old) as dose 2, single for COVID-19 immunisation. Medical history included that she had bipolar for at least 20 years, and she has been in remission for the last 6, She has had the peripheral neuropathy for 15 or 20 years at least, She had surgery, a right knee replacement, and she got the first dose before she went in for surgery in the hospital on 09Apr2021. In the hospital they gave her 2 different antibiotics. She doesn't know if that has anything to do with it or not. She had the antibiotics on 09Apr2021 when she had her knee replaced. She doesn't know the antibiotics they gave her. She verifies her knee replacement was on 09Apr2021. Her dad had cancer and her moms dad had diabetes. That, scoliosis, and stroke are all that runs in her family. Patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Solution for injection, Lot number: ER8727 and expiration date: Jul2021), via an unspecified route of administration in arm left on 25Mar2021 at 08:30 as dose 1, single for COVID-19 immunisation. Patient did not receive any other vaccine on the same day of Pfizer vaccine. The patient's concomitant medications were not reported. The patient on the night she got the second dose of the vaccine she went straight to bed. She had chills and everything and went to bed. The first night a bunch of her symptoms went away but the others remained. She had chills on 29Apr2021. She also had a low grade fever on 29Apr2021 that went away the next day 30Apr2021. The chills went away the next day on 30Apr2021. Sometimes she was cold and sometimes she was hot. She was in menopause so she can't say if she has recovered or if these are due to it. She was tired and stayed in bed. She has recovered completely from the low grade fever. She stated something cuts off in her chest and neck area. On 01May2021, she has had a hard time breathing the first or second day after the shot and at night she was up coughing. What happens when she lays down she loses her breath. She spent the first 2 days in bed. She coughs and then can't breathe at all. She has fatigue as well and she was in bed for 2 days because of the fatigue and stuff. She has an appointment with her physician next week. She wanted to report this anyway in case. She doesn't know the number for her physician's address, but it is on University Drive. She does not have an email available for her physician. All of these symptoms were still going on now. Her trouble breathing was mostly at night and can happen a couple times during the day when she lies down. She doesn't sleep laying down all the way, she was up a little bit. It starts with a cough and then she was not able to breathe. It is like something catches her breath. The first dose was in an old police building and where she got the second dose used to be a call centre in a big building. The adverse event did not require to visit Emergency Room or Physician Office. No prior Vaccinations (within 4 weeks). Patient was not hospitalized. No AE following prior vaccinations. On 30Apr2021, outcome of the events chills and low grade fever was recovered. The outcome of the events something cuts off in her chest and neck area was unknown while the outcome of hard time breathing, fatigue and at night is up coughing was not recovered.  No follow-up attempts are needed. No further information is expected.