cellulitis came back/worsening of the symptoms, cellulitis is now hot, with a swollen bump in the middle of it; This spontaneous case was reported by a consumer and describes the occurrence of CELLULITIS (cellulitis came back/worsening of the symptoms, cellulitis is now hot, with a swollen bump in the middle of it) in a 62-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included COVID-19 (She was not hospitalized because of COVID) on 11-Aug-2021, Cellulitis (cellulitis in her leg constantly for 7 to 9 years), Accident, Headache, Sinus disorder, Throat discomfort, Speech loss, Hematological infection (kept coming back for the past 20 years) in 2002, Fever, Pneumonia and Sickness. Previously administered products included for Pneumonia: pneumonia shot. Past adverse reactions to the above products included No adverse event with pneumonia shot. Concurrent medical conditions included Drug allergy (Morphine allergy), Allergy to NSAIDs (NSAIDs allergy), Thyroid function abnormal and Blood pressure abnormal.   On 09-Aug-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 06-Sep-2020, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced CELLULITIS (cellulitis came back/worsening of the symptoms, cellulitis is now hot, with a swollen bump in the middle of it) (seriousness criterion medically significant). The patient was treated with AMOXICILLIN for Cellulitis, at a dose of for a couple of weeks. At the time of the report, CELLULITIS (cellulitis came back/worsening of the symptoms, cellulitis is now hot, with a swollen bump in the middle of it) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 11-Aug-2021, SARS-CoV-2 test: positive (Positive) Positive.         Concomitant products included thyroid medicine and blood pressure medicine. She was not hospitalized because of COVID, but she seek medical care she went to a walking clinic as she got pneumonia but it did not go below 90.  Patient stated that her cellulitis was an effect of the blood disease she had since 20 years ago but the Moderna COVID19 vaccine was making it go away, within 2 weeks of receiving the Moderna shot it was gone which lasted 2 years. Patient had been getting cellulitis in her leg constantly for 7 to 9 years and because of this she had marks in her leg. When the patient got the Moderna shot the cellulitis went away and the cellulitis had stayed away until about 1 month ago that started coming back. Patient stated that she used many antibiotics to treat her condition but nothing help but the Moderna shot and that the Moderna COVID19 vaccine was the only thing that cleared up her cellulitis. The patient did not experienced a similar event in the past.  Company comment: This spontaneous case concerns a 62-year-old, female patient with, relevant past medical history of Cellulitis (cellulitis in her leg constantly for 7 to 9 years), who experienced the unexpected serious event of Cellulitis (seriousness criteria medically significant) which occurred unspecified day after the third dose of mRNA-1273. Patient's relevant past medical history of Cellulitis (cellulitis in her leg constantly for 7 to 9 years) remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.    This case was linked to MOD-2022-556381 (Patient Link).; Sender's Comments: This spontaneous case concerns a 62-year-old, female patient with, relevant past medical history of Cellulitis (cellulitis in her leg constantly for 7 to 9 years), who experienced the unexpected serious event of Cellulitis (seriousness criteria medically significant) which occurred unspecified day after the third dose of mRNA-1273. Patient's relevant past medical history of Cellulitis (cellulitis in her leg constantly for 7 to 9 years) remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.