Little bit of fever; A little bit of a chill; Throat ache; Arm soreness; Heart burn; not feeling well; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 48-year-old female patient received bnt162b2 omi xbb.1.5 (COMIRNATY (2023-2024 FORMULA)), on 30Sep2023 at 15:30 as dose 1, single (Lot number: HH7595) at the age of 48 years, in arm for covid-19 immunisation. The patient's relevant medical history included: "AFib" (unspecified if ongoing); "Asthma" (unspecified if ongoing); "heartburn" (not ongoing). Concomitant medication(s) included: DILTIAZEM taken for atrial fibrillation; ALVESCO taken for asthma. Past drug history included: Pepcid for heart burn, notes: because of heart burn sometimes, but patient hasn't had it in years until today. Vaccination history included: Bnt162b2 (Dose 1), for COVID-19 immunization; Bnt162b2 (Dose 2), for COVID-19 immunization, reaction(s): "I've only had reactions after the second one which is normal"; Bnt162b2 (Dose 3), for COVID-19 immunization; Bnt162b2;bnt162b2 omi ba.4-5 (Dose 4), for COVID-19 immunization. The following information was reported: MALAISE (non-serious) with onset 2023, outcome "unknown", described as "not feeling well"; DYSPEPSIA (non-serious) with onset 30Sep2023, outcome "not recovered", described as "Heart burn"; CHILLS (non-serious) with onset 01Oct2023, outcome "unknown", described as "A little bit of a chill"; PAIN IN EXTREMITY (non-serious) with onset 01Oct2023, outcome "unknown", described as "Arm soreness"; PYREXIA (non-serious) with onset 01Oct2023, outcome "unknown", described as "Little bit of fever"; OROPHARYNGEAL PAIN (non-serious) with onset 01Oct2023, outcome "unknown", described as "Throat ache". Therapeutic measures were taken as a result of dyspepsia. Additional information: Consumer called to report a side effect. She just spoke to a friend and colleague of hers who has the same side effect, heart burn after this last COVID vaccine, Comirnaty. On Saturday afternoon at 3:30, patient got the vaccine. She has had all her vaccines through Pfizer and only had reactions after the second one which was normal. All the other ones, she's been fine, perfect, not a problem. This is her5th vaccine. Got the vaccine at 3:30, and around in the evening, started getting a little bit of heart burn and thought to take Pepcid, not a problem and then the next morning she had the usual side effects, a little bit of fever, a little bit of a chill, throat aches, the arm soreness but what was really bad was the heart burn. It was a really bad heart burn and then she went to have another one of Pepcid. Maybe it was something she ate or something but she didn't eat anything. She had the ordinary, kept to a very plan diet to begin with. She couldn't even go to school because she teach, couldn't go to a school on Monday and then yesterday and was working at home, also feeling worse because she was scrunched in, been sitting. Patient called her doctor's office, her health plan and they told her to switch to Prilosec instead to see if that helps with the heart burn and they don't, they don't think its a side effect or anything. No one believed that it would be a side effect of the vaccine but this morning when patient was talking to her friend, they had a colleague that had the exact same side effect as patient did after the vaccine. Patient also mentioned she was not feeling well and has to find a way to get back to work while standing up.