Significant Chills; severe pain on left arm from hand to shoulder, up neck to left ear and around base of head, down across left shoulder blade on back to midline; but severe pain on left arm from hand to shoulder, up neck; but severe pain on left arm from hand to shoulder, up neck to left ear; pain around base of head; pain radiated on front of chest to midline/pain radiated on front of chest to midline; could not raise the arm for 2 days; pain in midline breastbones(sternum); However on the third dose...I had fever of 103 plus degrees for FOUR (4) DAYS; severe exhaustion; severe pain on left arm/ Pain at injection site; Off label use; booster; This is a spontaneous report from a contactable pharmacist (patient).   A 67-years-old non pregnant female patient received third dose of bnt162b2 (PFIZER-BIONTECH COVID-19 m-RNA VACCINE, formulation: solution for injection, lot number: FF2588), via intramuscular route, in arm left (left shoulder) on 07Sep2021 at 16:00 (age at vaccination 67 years) as dose 3 (booster), single for covid-19 immunisation. Medical history included 2 complete knee replacements on an unknown date in Oct2020 and on an unknown date Sept 2021 well after shot 3, mild hypothyroidism since an unknown date in 2019 and ongoing and took Synthroid (Levothyroxine) for that , ulcerative colitis from an unknown date in 2019 and ongoing and used Remicade glowks infusion , CA R+ Breast from an unknown date in 2002 to lumpectomy- no lymph no recurrence layers involvement 4x chemo + radiation, immunosuppressed due to Remicade use for UC, ongoing. The patient did not have Covid prior vaccination. There were no prior vaccinations (within 4 weeks). Concomitant medications included celecoxib (CELEBREX) 100mg as anti inflammatory from an unknown date in 2020 and ongoing via oral route; acetaminophen 500mg taken for pain from an unspecified start date and ongoing via oral route; levothyroxine sodium (SYNTHROID) taken for mild hypothyroid from an unknown date in 2020 and ongoing. The patient had Remicade Infusion on 08Jul2021. The patient previously took second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 m-RNA VACCINE, formulation: solution for injection, Lot: EL9269), via intramuscular route, in arm left on 19Feb2021 at 18:00 (age at vaccination 67 years) for covid-19 immunisation and experienced mild soreness and low grade fever for a few hours and via unspecified route, in arm left on 29Jan2021 at 18:00 (age at vaccination 67 years) as dose 1, single (lot number: EN5318) for covid-19 immunisation and experienced slight soreness. The patient previously had ciprofloxacin and experienced drug allergy. The patient had fever of 103 plus degrees on 07Sep2021 at 23:00 for four (4) days (total days with fever 7 days), then it began to fall gradually over next three days; severe exhaustion for 1 week on 07Sep2021 at 23:00; no redness, but severe pain on left arm from hand to shoulder, up neck to left ear and around base of head, down across left shoulder blade on back to midline, pain in midline breastbones(sternum)/ pain radiated on front of chest to midline; could not raise the arm for 2days on 07Sep2021 at 23:00. It was later reported that pain at injection site extended down to left hand, up to shoulder and neck to ear, wrapped around base of neck to midline, extended across shoulder blade in back and across chest from collar bones to midline breastbones(sternum) could not raise her arm (left) for 2 days. The patient had chill significant for 2 days on 08Sep2021 at 01:00. The patient underwent lab tests which included body temperature as 103 on 07Sep2021. The patient was not Covid tested post vaccination. Treatment was taken for event fever less than equal to 103 degree and chill significant with anti-pyretic around the clock, severe pain on left arm from hand to shoulder, up neck to left ear and around base of head, down across left shoulder blade on back to midline, pain radiated on front of chest to midline; could not raise the arm with OTC pain MEOS. No treatment was given for fatigue. The outcome of the events severe pain on left arm from hand to shoulder, up neck to left ear and around base of head, down across left shoulder blade on back to midline, severe exhaustion, severe pain on left arm/ Pain at injection site, pain in midline breastbones(sternum)/ pain radiated on front of chest to midline was recovered on 13Sep2021, could not raise the arm for 2days was recovered on an unspecified date in 2021, fever of 103 plus degrees was recovered on 12Sep2021, significant chills was recovered on 10Sep2021.  Follow-up attempts are completed. No further information is expected.