Patient stated, yesterday afternoon she noticed a rash on both forearms. Red, itching, warm, red, not so much bumpy just red.; Feeling a little itchy on parts of body; Scalp itching; caller developed a red rash on her bilateral forearms & scalp started itching; Little fatigued; Thumb tingling and warm; Thumb tingling and warm; Patient stated, yesterday afternoon she noticed a rash on both forearms. Red, itching, warm, red, not so much bumpy just red.; Normally wakes up at 04:00 now wakes up at 07:00; This is a spontaneous report from a contactable consumer (patient). A female patient of an unspecified age received BNT162b2 (PFIZER BIONTECH COVID-19 mRNA VACCINE, Solution for injection, Lot number- unknown) via an unspecified route of administration on 16Mar2021 as 1st dose, single for COVID-19 immunization. Medical history included had a mastectomy this past December also stated had 4 lymph nodes removed. Stated she had always been sensitive to chemicals but seems like she is more so now since mastectomy. Previously took epinephrine, steroids they increase her blood pressure really bad. Concomitant medications included omeprazole at 40 mg from 11Mar2021 and at 20 mg from 13Mar2021 to an unspecified stop date for acid reflux and H Pylori, famotidine (PEPCID AC) from 17Mar2021 to 18Mar2021. On 18Mar2021 (Thursday), afternoon she noticed a red rash on her bilateral forearms & scalp started itching, red, itching, warm, not so much bumpy just red, scalp itching, feeling a little itchy on parts of body, Thumb tingling and warm, Little fatigued. After about 30 minutes scalp was itching and then stopped and she looked at both forearms. After about 30 minutes subsided and she was still feeling itchy and took one teaspoon of Benadryl. Has not had anymore rash pop up, is feeling a little itchy on parts of the body. They cannot use Epinephrine at the dentist. Is scheduled to have second dose on 06Apr2021 and is really worried now. This past Saturday her doctor called in Omeprazole 40mg for acid reflux and HPylori. She took it on 11Mar2021 and was itching. She did not initially connect it with the Omeprazole, thought it was from salsa although she has eaten salsa before. Pharmacist recommended her to do a process of elimination. On 13Mar2021 she went and got over the counter Omeprazole 20mg and about an hour later broke out in a rash, big welts, stronger reaction than before. Then she was afraid coming up on the Tuesday because she was scheduled for her COVID 19 Vaccine. She went ahead to got the vaccine at the clinic. She added after the vaccination her left thumb felt a little tingly, it was fleeting it would go and come. She was also warm during her hour. She does not do anything with her right arm after her mastectomy. The sensation in thumb was very fleeting. After sitting for an hour she left and was a little fatigued, not like most people. Most people say there were knocked off their feet. Stated her son-in-law was knocked off his feet after his. Mentions also that he is an essential worker who had Covid back in July. Stated that her daughter said she felt like she had taken a lot of Benadryl after her vaccine, was just sleepy. Caller states that for herself and her sister it feels like it brought them down to normal people level. Stated they were way up there anyways. Caller mentioned she normally wakes up at 0400 and now wakes up at 0700 since the shot. Rash was primary concern. Doesn't know if it is from the Omeprazole. Stated pharmacist doesn't think it would still be from the Omeprazole at this time. Caller stated she doesn't know, doesn't know the half-life of Omeprazole. Mentioned that she took Pepcid after shot, on Wednesday and Thursday. States could there be something in the Pepcid that she's allergic too; something like that is in the Omeprazole. Mentioned has taken Pepcid tablets before. However, not by itself. She has taken it along with Benadryl. Said she had an appointment later today and needs to get some stuff done. Mentioned that she was wondering if she was more sensitive to chemicals now than before since they took out 4 lymph nodes with her mastectomy. Stated this effects her lymphatic system. Does not remember being this sensitive before. Still questioning if she should take her second vaccine. Mentions should she go and see and allergist. States they had told her previously they couldn't test for chemicals, but maybe now they could. Further information requested. The outcome of the event feeling a little itchy on parts of body was not recovered, outcome of the event scalp itching was recovered on an unspecified in Mar2021 and outcome of the other events was unknown.  Information about Batch/lot number requested.