she is going to have cataracts removed; itching under the skin after receiving a second dose?; she has an allergic reaction; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  An 83-year-old female patient received BNT162b2 (BNT162B2), on 15Apr2021 as dose 2, single (Lot number: EN6205) at the age of 83 years for covid-19 immunisation. The patient's relevant medical history included: "low thyroid" (unspecified if ongoing); "anxiety" (unspecified if ongoing). Concomitant medication(s) included: LEVOTHYROXINE oral taken for hypothyroidism; CITALOPRAM taken for anxiety. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Batch/lot number: EN6205   , Dosage text: first dose injected into left arm below the shoulder), administration date: 25Mar2021, when the patient was 83-year-old, for Covid-19 immunization. The following information was reported: HYPERSENSITIVITY (non-serious) with onset Apr2021, outcome "unknown", described as "she has an allergic reaction"; CATARACT (medically significant), outcome "unknown", described as "she is going to have cataracts removed"; PRURITUS (non-serious), outcome "not recovered", described as "itching under the skin after receiving a second dose?". The events "itching under the skin after receiving a second dose?" and "she has an allergic reaction" required physician office visit. The patient underwent the following laboratory tests and procedures: Biopsy: Unknown results, notes: She says her allergist did a biopsy, which didnt help her either. Therapeutic measures were taken as a result of pruritus, hypersensitivity.  Clinical course: Patient said she had the Pfizer COVID-19 vaccine second shot in Apr2021 and she had an allergic reaction where her full body was itchy and skin where it was itchy was not raised skin, it was under the skin. She said she went to her dermatologist and got CORTISONE, which worked, but she cant take that forever. She said she also tried CERAVE cream, Calamine lotion and Cetirine HCl (clarified to Cetirizine HCl). She said she also been taking Fexofenadine also, which had been helping for over a year, but when she stopped what she was taking the itch comes right back. She says her allergist did a biopsy, which didn't help her either so she was trying to find out what can help this. Patient would also like to know if anyone else reported this. Patient reported treatment for events as follows: Cetirizine HCl 10mg: Patient said she took this for the itch, and it didn't make any difference. She said she took this twice a day by mouth. She said every time her doctor would give her tablets to take she would take it as prescribed, but it didn't get better or take care of the itch. Patient said she will see if she can find the pill box, since it was prescribed but she doesn't take that anymore for the itch. She said the label says common brand is Zyrtec. She says she cant see the NDC, and says the box is covered by pharmacy label. She says the pharmacy label says discard after 06 Oct 2022, and she doesn't see LOT on pharmacy label. Caller says that she is using a magnifying glass to read the label which she doesn't normally need it but next month she is going to have cataracts removed, so right now she was using a magnifying glass since the writing is so small on these things. Patient had clarified that she was reading from a pharmacy label previously.  Cerave Moisturizing Cream: Patient said this was like a lotion, she would put it on in the morning after she would wash up, her doctor said to keep her skin moist all times, she used it on her whole body.  Cortisone NDC/LOT/EXP: Unknown. Patient said that this was a pill and that she doesn't have that anymore, it did work. She said her doctor started her off on a low dose and then took her off it, and started prescribing her other things that didn't work, and then after she tried about three different things, he put her back on a higher dose of Cortisone for about a week and then after that the doctor said it was not really good to be on Cortisone for too long, so ever since then she tried other things, but the only thing that worked was antihistamine, Fexofenadine 180mg, which she takes twice a day by mouth.  Famotidine 20mg: Patient said that she took one tablet by mouth twice a day, and this did not work. She said this medication is in a box with a pharmacy label covering UPC/LOT/EXP, and provides discard after date from pharmacy label of 03Dec2022.  Diphenhydramine: Patient said she was taking one every night and ran out of that, and continued taking the Fexofenadine twice a day, which that was working so she thought why bother taking the other one. Patient was unable to locate the Diphenhydramine to provide further information for it, including NDC/UPC/LOT/EXP. Calamine: Patient said this was a lotion, just bought over the counter because she can use it for other itches and thought it might help, which it helped a little bit and took the intenseness away but not enough. No further details provided about Calamine lotion. Further, Patient said when she itches, if she scratched it then it would burn. Patient said none of it, but some things worked, she would take the medication and then finish it and then go back to having the itch again. AE Outcome: Patient said with the itching it is hard to say, since she was never off the medication, and it was always the same until she took the antihistamine, it was the same every time and would come back when she stopped the medication.