lymph nodes were swollen/lymph nodes became very big; lymph nodes painful; use left arm to pick up her right arm when she is sleeping; breast swollen to twice the usual size; nipple felt painful; lymph nodes on the right arm to her breast was warm to touch; headache after booster shot/headache was on top of the head and feels like squeezing and releasing/headache on the right side; body ache after booster shot; This spontaneous case was reported by a consumer and describes the occurrence of PAIN (body ache after booster shot), BREAST SWELLING (breast swollen to twice the usual size), NIPPLE PAIN (nipple felt painful), FEELING HOT (lymph nodes on the right arm to her breast was warm to touch) and HEADACHE (headache after booster shot/headache was on top of the head and feels like squeezing and releasing/headache on the right side) in a 67-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 049C21A, 00GB21A and 036A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Blood pressure abnormal. Concomitant products included LOSARTAN for Blood pressure, COLECALCIFEROL (VITAMIN D3) for an unknown indication.   On 15-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 02-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Nov-2021, the patient experienced PAIN (body ache after booster shot) and HEADACHE (headache after booster shot/headache was on top of the head and feels like squeezing and releasing/headache on the right side). On 01-Dec-2021, the patient experienced BREAST SWELLING (breast swollen to twice the usual size), NIPPLE PAIN (nipple felt painful) and FEELING HOT (lymph nodes on the right arm to her breast was warm to touch). On an unknown date, the patient experienced LYMPHADENOPATHY (lymph nodes were swollen/lymph nodes became very big), LYMPH NODE PAIN (lymph nodes painful) and VACCINATION SITE PAIN (use left arm to pick up her right arm when she is sleeping). The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) at a dose of 500 mg and IBUPROFEN (MOTRIN [IBUPROFEN]) at a dose of 600 mg, (3 doses). At the time of the report, PAIN (body ache after booster shot), BREAST SWELLING (breast swollen to twice the usual size), NIPPLE PAIN (nipple felt painful), FEELING HOT (lymph nodes on the right arm to her breast was warm to touch), LYMPHADENOPATHY (lymph nodes were swollen/lymph nodes became very big), LYMPH NODE PAIN (lymph nodes painful) and VACCINATION SITE PAIN (use left arm to pick up her right arm when she is sleeping) outcome was unknown and HEADACHE (headache after booster shot/headache was on top of the head and feels like squeezing and releasing/headache on the right side) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Mammogram: normal (normal) Normal. On an unknown date, X-ray: no obvious change (normal) no obvious change.         Prior to the Moderna booster, she had received two doses of the Moderna Vaccine. Since the booster, she had headache, body aches but no fever. She noticed that under her right arm (injection site arm), the lymph nodes were swollen and became very big and painful. During shower, she noticed that her breast was swollen to twice its usual size. Her mammogram was done recently, and it was normal. Her nipple felt painful. Upon examination, the lymph nodes on the right arm all the way to her breast was warm to touch. Her headache was mainly on the right side. The medications that she took were not really working. The relief was only for a while. The headache was on top of the head and felt like squeezing and releasing. It relieved a little after medication but not too much. She mentioned that she didn't like to take too many medications. She had to use her left arm to pick up her right arm when she was sleeping. She decided to go ahead with the administration of the booster shot on the right arm, instead of the left arm, even after the prolonged pain that affected her right arm after the second dose. This was view of her duty to care for her family member. The primary doctor in third contact tab had done an X-ray for her and found no obvious change.   This case was linked to MOD-2021-403385 (Patient Link).