After the first vaccine patient scalp started to itch significantly; Psoriasis symptoms seemed a little worse; This is a spontaneous report from a contactable consumer. A 53-years-old female non-pregnant patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Solution for injection, Lot Number: EW0161/Batch number was not reported), dose 1 intramuscular, administered in arm left on 16Apr2021 at 12:30 (at the age of 53-years-old) as dose 1, single for covid-19 immunisation at Pharmacy. Medical history included ongoing psoriasis Onset date (Childhood), hypothyroidism from 2005 and ongoing, antiphospholipid antibodies from an unspecified date in 2012 and ongoing, caesarean section from an unspecified date in 1997 to an unknown date, caesarean section from an unspecified date in 2001 to an unknown date, hysterectomy from an unspecified date in 2012 to an unknown date, hernia repair from an unspecified date in 2012 to an unknown date, covid-19 from an unspecified date in Dec2020 to an unknown date, psoriasis from an unknown date and unknown if ongoing, gastrooesophageal reflux disease from an unknown date and unknown if ongoing and anxiety from an unknown date and unknown if ongoing. Concomitant medication(s) included levothyroxine sodium (SYNTHROID) at a dose of 50 ug, daily taken for hypothyroidism from an unspecified start date and ongoing, rivaroxaban (XARELTO) at a dose of 10 mg, daily taken for antiphospholipid antibodies from an unspecified start date and ongoing, pantoprazole (PANTOPRAZOLE) at a dose of 20 mg, daily taken for gastrooesophageal reflux disease from an unspecified start date and ongoing, escitalopram (ESCITALOPRAM) at a dose of 10 mg, daily taken for anxiety from an unspecified start date and ongoing, calcium (CALCIUM) taken for an unspecified indication, start and stop date were not reported, vitamin b complex (SUPER B COMPLEX [VITAMIN B COMPLEX]) taken for an unspecified indication, start and stop date were not reported, fish oil (FISH OIL) taken for an unspecified indication, start and stop date were not reported, iron (IRON) taken for an unspecified indication, start and stop date were not reported, calcium citrate, magnesium citrate (MAG CITRATE) taken for an unspecified indication, start and stop date were not reported, multivitamin [vitamins nos] (MULTIVITAMIN [VITAMINS NOS]) taken for an unspecified indication, start and stop date were not reported and curcuma longa root (TURMERIC CURCUMIN) taken for an unspecified indication, start and stop date were not reported. The patient did not receive any other vaccines within four weeks prior to the vaccination. Prior to the vaccination, the patient was diagnosed with COVID-19. Since the vaccination, the patient had not been tested for COVID-19. The patient experienced psoriasis symptoms seemed a little worse on an unspecified date in Apr2021 and after the first vaccine patient scalp started to itch significantly on 17Apr2021. The clinical course was as follows: Patient has plaque psoriasis, after 1st dose she noticed that her psoriasis symptoms seemed a little worse. Her plaque psoriasis is only on her scalp. The patient underwent lab tests and procedures which included chest x-ray: normal (Resolved pneumonic), mammogram: normal on 17Mar2021, electrocardiogram ambulatory: normal on 25Mar2021 and echocardiogram: normal on an unspecified date in Mar2021. No treatment was given for the events. The dose number 2 was scheduled on 14May2021. The outcome of the events was not resolved.  Follow-up attempts are completed. No further information is expected.