Initial report received from a consumer, who is also the patient, on 24 March 2014. A 28-year-old female patient, with a history of seasonal allergies and "allergies to certain meds", received an intramuscular left deltoid injection of FLUZONE (lot UH716AD) on 28 September 2012. She had no illness at the time of vaccination. Within an hour of vaccination, the patient developed widespread hives, sneezing, watery eyes, and shortness of breath. She was on her way home from her physician's office when the symptoms began, and she stopped at an urgent care center where she was treated for the allergic reaction and released. Outcome was reported as recovered. Documents held by sender: None. Follow-up information received from a healthcare professional on 28-May-2014: According to the reporter, a VAERS report has already been completed by the physician who does not wish to complete another report. No more information on the case was received through this follow-up. Follow-up information was received on 18 June 2014 from a health care professional. The patient has a history of being allergic to AUGMENTIN, OMNICEF, Tdap and BACTRIM. Treatment for the allergic reaction was prescribed by the ED (emergency department). The patient has not received an influenza vaccine since 2012. No further information was provided at the time of the report. Outcome remained recovered. Follow-up information was received from a healthcare professional on 30 July 2014. The patient has known allergies of AUGMENTIN and OMNICEF. She has a history of chronic sinusitis and sinus surgery, date not reported. She consumes alcohol socially. The patient has a history of environmental, seasonal and perennial allergies mainly in the spring and fall. She currently takes the following medications: CLARITIN (13:25 KMW7), LESTRIN 21 1/20 (13:26 KMW7), FLONASE (13:26 KMW7) and BACTRIM DS: 1 tab by mouth twice a day (13:26 KMW7). She was at the doctor's office on 28 September 2012 with a diagnosis of sinus infection. The patient was given her flu shot at 11:30 on that day and also was prescribed BACTRIM DS. She took her first dose of BACTRIM DS at 12:00 and about 5 minutes later she started sneezing a lot and was wheezing. She denied throat/tongue/facial swelling. She denied asthma, but stated that she has allergies and when her allergies bother her she has problems with breathing/wheezing. When she got home she had a rash on her abdomen, elbows, thighs that resolved at an unspecified time. She did not take anything for symptoms. She also reported rhinorrhea, cough, wheezing and headache. The patient stated that she has received flu shots at least 10 times without problems and has been on BACTRIM DS 3 times without problems (previously reported an allergy to BACTRIM). She reported feeling better now, but was still tired and a "little wheezy". She denied a fever or problems with hives in the past except when she has an allergic reaction to OMNICEF and AUGMENTIN. The physician discussed that he could have an allergic reaction but it was questionable whether it was related to flu or BACTRIM DS. She was prescribed an inhaler (PROAIR), ZPAK ZITHROMAX and ZPAK and allergy medication, including CLARITIN which she had at home. The patient was diagnosed with allergic reaction and an additional event of allergic rhinitis. The patient outcome is recovered. Documents held by sender: Medical records.