Thought she was having a heart attack; anxiety; This is a spontaneous report from a contactable consumer (patient) from a Pfizer-sponsored program.  A 61-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot Number: EN6202), intramuscular, administered in left arm on 03Mar2021 at 14:30 (at the age of 61-year-old) as DOSE 1, SINGLE for covid-19 immunisation. The report is related to Study Programme. The patient medical history included stage 4 breast cancer (Diagnosed 15 years ago this August), stage 4 bladder cancer and was taking Chemo (She was off Chemo for a while before having the first dose of the Pfizer COVID Vaccine), rapid heartbeat, a little hair loss (when she was on Chemo), 33 years ago she had compromised immune status (doctors say it was ringworm and hookworm and then saw a dermatologist that said it was autoimmune disease), seasonal allergies (allergies to prescription drugs specifically antibiotics), she had an allergic reaction to Bactrim, anything that had Sulfa drugs in it (they make her itch incredibly bad), She had a little reaction to Penicillin (it makes it difficult to breathe, but she did not have swelling of throat), pain medication, they have not found one her body can tolerate, opioids make her itch (one they put her on, she did not have that bad of a reaction to). The Oxycodone 5mg is the name of the one she can take. She cannot take Hydrocodone. They gave her some strong ones with the first chemo. Brother and died had heart attack. Hers was caused by Stage 4 cancer and PICC line. She confirmed she did not have a heart attack. PICC Line caused damage to heart and when she had stage 4 breast cancer, it causes damage to your heart and that was when she started having trouble with the PICC line in 2020. They had to start her Chemo and she could not take her last 2 treatments. She took 80%. They figured she got enough Chemo. They gave her a child's dose because she weighs so little. She wears an ostomy bag since she does not have a bladder. She had to dehydrate before she went to get the vaccine. She did not get time to heal from major surgery before her doctor made her start with Chemo. They were trying to save her life. She was a Withheld girl and said she would have been ok with it. The patient's concomitant medications included Metoprolol ER Succinate 50 mg capsule. Once daily by mouth since 2020 for high heart rate. Patient did not receive any vaccine Prior within 4 prior vaccinations. Previously she took she took flu shot and did not have any. The patient experienced heart attack on 03Mar2021 at 18:00 and anxiety in Mar2021. She reported that when she had first dose, she thought she was having a heart attack. Even before having vaccine, she had a history of a rapid heartbeat and does take heart medication for that. She asked her brother, who also took his vaccine the next day, if he had any problems and he did not. He told her to take a Benadryl. It was so bad; she felt her heart would come out of her chest and made her go into anxiety. So that was when she took the Benadryl (25 mg), and she did feel better immediately. Within a little bit, it was gone. It lasted just a couple of hours, and then it stopped. It was reported that she saw cardiologist and pulmonary specialist and had to be put on oxygen but this was prior to the vaccine. She also had a PICC line placed prior to the vaccine and that also caused her heart issues. She was so scared of the COVID. Even if she got the vaccine, does not mean she will survive. She needs to cut her ostomy supplies and get in the shower and this was prior to getting the vaccine. She had anxiety when he came home from work, and she wipes everything down. She worried about it and had to let herself calm down instead of having anxiety. She has calmed down a lot. She said her doctor told her she could feel like she may have a little of a cold if she got it. The outcome of heart attack was recovering, and outcome of anxiety was unknown.