Headache / She has a little dull headache; Fuzzy; Slightly chillier; Cold; She got so nervous / She is scared that it didn't work; Felt pain at the injection site. It is painful when she touches her arm / felt a twinge at the injection site; This is a spontaneous report from a Pfizer-sponsored program Support and received from a contactable consumer or other non-health care professional (patient). A 63-years-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot Number: Unknown), via an unspecified route of administration on 15Feb2021 12:00 as dose 2, single for COVID-19 immunisation and received ibuprofen (MOTRIN [IBUPROFEN]), via an unspecified route of administration from an unspecified date (Batch/Lot number: Unknown) to an unspecified date, at 400 mg, 1x/day (takes two of the 200mg over the counter Motrin every morning) for arthritis. Medical history included, thyroid, racing heart (medication for thyroid, and fast heart rate (Toprol), arthritis from an unknown date and unknown if ongoing. Concomitant medications included metoprolol succinate (TOPROL) taken for palpitations, start and stop date were not reported. The patient previously took first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, Batch/Lot Number: Unknown) via an unknown route of administration on 25Jan2021 as dose 1, single for COVID-19 immunisation and experienced arm was a little sore. The patient received 1st dose of covid vaccine 3 weeks ago. Had 2nd of vaccine dose yesterday. With 1st dose arm was a little sore and with 2nd dose facility told caller she might had more soreness. Came home got email from friend saying not take Tylenol or Advil. No one told her this information prior to getting vaccine. Said she takes 2 Motrin every morning for Arthritis and now was freaking out that vaccine won't be good. She was trying to stay calm. It was nothing bad about Pfizer. She was proud to say she will be 64 on her birthday. Her birthday was on Friday. She got so nervous. She was calling because she was so excited that she was done. This time she got it at 12:00 in the afternoon and at 9:00 PM, On 15Feb2021 she felt pain at the injection site. It was painful when she touches her arm. She has a little dull headache. She is scared that it didn't work. After second dose caller said around 9 pm she experienced: injection discomfort/pain- definitely more severe than 1st dose, but tolerable. If I go above my boobs, over my head, or touch it, I feel it. No different than a tetanus shot. Caller also experienced slightest dull Headache, over my forehead and over my eyes. Feels a little fuzzy, feels a little off, slightly chillier than i usually feel, a bit cold. Caller said, injection site pain was like tetanus shot, tetanus shots feel worse than a flu shot. Caller said the vaccination provider told her that side effects could be a little worse after the 2nd dose and was told by the nurse to take Tylenol or Motrin if you had side effects. Caller said, she petrified that my vaccine did not work, because she took her daily Motrin before the vaccine. Caller asked, the fact that my arm was hurting, that was a good sign. I know people got side effects, and that mean your body was working with the vaccine. Caller was also discussing husbands experience with both dose of vaccine. Husband, was 65 year old male. The following experience information given by caller/wife. after the 1st dose, he had arm pain very quickly/right away. I think the administrator you know how you got the injection and then you get pain to the elbow. I think they hit a nerve. Caller said her husband came out from getting the 1st dose and said, my arm, it was killing me right after his dose. After 2nd dose normal injection site pain. Only when you go midway up and back and touching of injection site. Arm pain on the same level. The outcome of the events was reported as unknown.  Description of complaint: On 25Jan2021 she had first dose. The nurse said she may feel nothing, but if she needed it caller could take Tylenol or Motrin. With the first shot she did not feel anything. She got it at 12:00 PM. At 2AM she felt a twinge at the injection site and she was so happy. Yesterday when she got it the nurse said you may not feel anything or you may need Motrin or Tylenol. The nurse said that caller may feel more than after the first one like a headache or muscle aches. A friend said not to take any analgesic because it completely eradicates the vaccine. She takes two of the 200 mg over the counter Motrin every morning. Before she got the vaccines they asked if she had any other vaccines and if she had COVID testing. No one ever asked if she took two Motrin. When she got this text she flipped out. Does that mean the vaccines did not work. She was scared that it did not work. They scared her and they made her feel that because she took the Motrin before the shot it won't work. Her husband started researching it and it said to continue mediations prescribed though it could effect the glands. She was scared that it didn't work. She does not understand why she did not read anything that said not to take Motrin. That was so confusing. She could had just not taken it. She was very upset. Caller clarified her question. Does Motrin effect the efficacy of the COVID vaccine. Caller declined to proceed with report. Caller asked, How long does it take for 2nd dose to protect me. it was 2 weeks or we do not know how long we are protected. Caller said, so if I went for antibody test in 2 weeks. should it come back, I believe everyone should do it (antibody testing). Caller asked, if there was not way of knowing if she truly protected or if Motrin did any harm. Do you think they would ask me to get the vaccine again and tell me not the take the Motrin before doses.  Information on the lot/batch number has been requested.  Follow-up (11May2021): Follow-up attempts completed. No further information expected.