swelling of the lower lip all puffed up; Pain; chills; low grade temp; muscle pain; joint pains; tiredness; The only thing that was little bit up was creatinine; She is not getting relaxed; Aches all over her body, she had body aches all over; She is not well at all; She has been very, very sick; This is a spontaneous report from a contactable consumer (patient's husband) via Medical Information Team. A 73-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation : Solution for injection, Batch/Lot number: Not reported) via an unspecified route of administration, on 16Apr2021 (at the age of 73 year old) as DOSE 2, SINGLE for Covid-19 immunization. Patient medical history include hypertension and cholesterol. Concomitant medication include clonidine (CLONIDINE) 0.1mg, labetalol (LABETALOL) 100 mg, spironolactone (SPIRONOLACTONE) 25 mg for Blood pressure, rosuvastatin (ROSUVASTATIN) 10mg for Cholesterol , acetyl salicyclic acid (ECOTRIN) 325mg for Blood thinning, benazepril (BENAZEPRIL) 10mg and nifedipine (NIFEDIPINE). Historical vaccine includes bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection, Batch/Lot number: Not reported) via an unspecified route of administration, on 25Mar2021 (at the age of 73 year old) as DOSE 1, SINGLE for COVID-19 immunization. The patient experienced swelling of the lower lip all puffed up, pain, chills, low grade temp, muscle pain, joint pains, tiredness, the only thing that was little bit up was creatinine, she is not getting relaxed, aches all over her body, she had body aches all over, she is not well at all, she has been very, very sick on an unspecified date. She began to have side effects on the 19th of 2021 and was subsequently seen in the Emergency room and her Primary care doctor. she took the second dose, tomorrow make it three weeks since she took it but she has been very sick for the past she has fever, aches all over her body and she is laid up with it and yesterday her lips became swollen and all puffed up she had body aches all over and it's not going away, they went to the emergency room last week memorial. Her current symptoms include Pain, chills, low grade temp, muscle pain, joint pains, tiredness, and swelling of the lower lip. Laboratory tests carried out includes red cell distribution, lymphocytes, the only thing that was little bit up was creatinine, she was at 1.37 with the creatinine, it was 90 something (Further not clarified hence not captured) test and she was negative for that, they did a chest x ray, blood work and urine, they did everything, and they send it to her primary care physician on Monday and he ordered some more test. Everything was negative. But she has to go back and see him again on Monday coming again, but she was not getting relaxed, she's still puffed up and this happened for two weeks. she was not well at all. Treatment received for the events includes Tylenol. she has been taking for 3 weeks and antibiotics. Tomorrow makes it three weeks since she had this adverse condition. The patient underwent lab tests and procedures which included blood creatinine: Increased, chest x-ray: unknown, lymphocyte count: unknown, red cell distribution width normal: unknown, sars-cov-2 test was negative on an unknown date. The outcome for all events was unknown.   No follow up attempts are needed, No further information is expected.