marks on her legs and arms are all peeling; legs bruised; legs swollen; swollen lymph nodes; chills; a fever 102; loss of bowel control for two weeks; flu like symptoms; constant migraine; blisters back of neck down the spinal cord; leg lesions(approximately the size of a 50 cent pieces that resemble cigar burns); was in a lot of pain; lost all the skin on the palms of hands, except for right hand (not so many blisters on her fingers); This spontaneous case was reported by a consumer and describes the occurrence of ANAL INCONTINENCE (loss of bowel control for two weeks), INFLUENZA LIKE ILLNESS (flu like symptoms), MIGRAINE (constant migraine), BLISTER (blisters back of neck down the spinal cord) and GRANULOMA ANNULARE (leg lesions(approximately the size of a 50 cent pieces that resemble cigar burns)) in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 023M20A and 098A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Autoimmune disorder (Patient has autoimmune disease (not specified).).   On 12-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 12-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 2 dosage form. On 13-Mar-2021, the patient experienced ANAL INCONTINENCE (loss of bowel control for two weeks), INFLUENZA LIKE ILLNESS (flu like symptoms), MIGRAINE (constant migraine), BLISTER (blisters back of neck down the spinal cord), GRANULOMA ANNULARE (leg lesions(approximately the size of a 50 cent pieces that resemble cigar burns)), PAIN (was in a lot of pain), SKIN EXFOLIATION (lost all the skin on the palms of hands, except for right hand (not so many blisters on her fingers)), CONTUSION (legs bruised), PERIPHERAL SWELLING (legs swollen), LYMPHADENOPATHY (swollen lymph nodes), CHILLS (chills) and PYREXIA (a fever 102). On 29-Mar-2021, the patient experienced SKIN EXFOLIATION (marks on her legs and arms are all peeling). The patient was treated with CELECOXIB (CELEBREX) for Pain, at a dose of UNK dosage form and CLOBETASOL PROPIONATE (CLOBETASOL [CLOBETASOL PROPIONATE]) at a dose of UNK dosage form. On 20-Mar-2021, MIGRAINE (constant migraine) had resolved. On 27-Mar-2021, ANAL INCONTINENCE (loss of bowel control for two weeks), BLISTER (blisters back of neck down the spinal cord), GRANULOMA ANNULARE (leg lesions(approximately the size of a 50 cent pieces that resemble cigar burns)), PAIN (was in a lot of pain), CONTUSION (legs bruised), PERIPHERAL SWELLING (legs swollen), LYMPHADENOPATHY (swollen lymph nodes), CHILLS (chills) and PYREXIA (a fever 102) had resolved. On 29-Mar-2021, INFLUENZA LIKE ILLNESS (flu like symptoms) had resolved, SKIN EXFOLIATION (lost all the skin on the palms of hands, except for right hand (not so many blisters on her fingers)) was resolving. At the time of the report, SKIN EXFOLIATION (marks on her legs and arms are all peeling) outcome was unknown.            Action taken with mRNA-1273 in response to the event was not applicable   This case was linked to US-MODERNATX, INC.-MOD-2021-060986 (E2B Linked Report).; Sender's Comments:  US-MODERNATX, INC.-MOD-2021-060986:Dose1