Skin reaction 12 days after booster; 12 days after booster she got hives which move around and they are uncomfortable; Itchy 12 days after booster/Anything touch skin, makes skin swell up, itch and sting; Sting 12 days after booster/Anything touch skin, makes skin swell up, itch and sting; Dermatographia 12 days after booster; Anything touch skin, makes skin swell up, itch and sting; This spontaneous case was reported by a consumer and describes the occurrence of SKIN REACTION (Skin reaction 12 days after booster), URTICARIA (12 days after booster she got hives which move around and they are uncomfortable), PRURITUS (Itchy 12 days after booster/Anything touch skin, makes skin swell up, itch and sting), PAIN OF SKIN (Sting 12 days after booster/Anything touch skin, makes skin swell up, itch and sting) and MECHANICAL URTICARIA (Dermatographia 12 days after booster) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 004F21A, 025B21A and 040A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Seasonal allergy.   On 07-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 02-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 31-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-Nov-2021, the patient experienced SKIN REACTION (Skin reaction 12 days after booster), URTICARIA (12 days after booster she got hives which move around and they are uncomfortable), PRURITUS (Itchy 12 days after booster/Anything touch skin, makes skin swell up, itch and sting), PAIN OF SKIN (Sting 12 days after booster/Anything touch skin, makes skin swell up, itch and sting), MECHANICAL URTICARIA (Dermatographia 12 days after booster) and SKIN SWELLING (Anything touch skin, makes skin swell up, itch and sting). The patient was treated with METHYLPREDNISOLONE for Adverse event, at a dose of 2 packs; DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency and CROMOGLICATE SODIUM (CROMOLYN [CROMOGLICATE SODIUM]) for Adverse event, at a dose of 200mg (10ml) to mix with water and drink 4 times a day. At the time of the report, SKIN REACTION (Skin reaction 12 days after booster), URTICARIA (12 days after booster she got hives which move around and they are uncomfortable), PRURITUS (Itchy 12 days after booster/Anything touch skin, makes skin swell up, itch and sting), PAIN OF SKIN (Sting 12 days after booster/Anything touch skin, makes skin swell up, itch and sting), MECHANICAL URTICARIA (Dermatographia 12 days after booster) and SKIN SWELLING (Anything touch skin, makes skin swell up, itch and sting) outcome was unknown.            The patients Doctor said it was dermatographia. Doctor gave one Methyl Prednisolone dose pack, and it did not help. Repeated the Steroid for 1 more pack, and there was no relief. Then suggested OTC antihistamine (Benadryl). Then she visited a second MD, whom stated it is caused by the booster. She gave Cromolyn liquid ampule 200mg (10ml) to mix with water and drink 4 times a day. It helped a little but not  No concomitant medications were reported.   This case was linked to MOD-2021-407507 (Patient Link).