moody; increased swollen joint; worsening joint pain; worsening depression; stenosis of back; hair loss after covid vaccine; This spontaneous case was reported by a consumer and describes the occurrence of SPINAL STENOSIS (stenosis of back), ALOPECIA (hair loss after covid vaccine), DEPRESSION (worsening depression), MOOD ALTERED (moody) and JOINT SWELLING (increased swollen joint) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect products included non-company products UPADACITINIB (RINVOQ) for Rheumatoid arthritis and PREDNISONE for Rheumatoid arthritis.    The patient's past medical history included Depression (felt like it was worse). Previously administered products included for Drug use for unknown indication: METHOTREXATE. Past adverse reactions to the above products included No adverse event with METHOTREXATE.   In 1973, the patient PREDNISONE (unknown route) dosage was changed to 5. In November 2020, the patient started UPADACITINIB (RINVOQ) (Oral) 15 milligram. On 30-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient started PREDNISONE (unknown route) 2.5. On an unknown date, PREDNISONE (unknown route) dosage was changed to 5 and PREDNISONE (unknown route) dosage was changed to 10 milligram. In February 2021, the patient experienced DEPRESSION (worsening depression). In March 2021, the patient experienced JOINT SWELLING (increased swollen joint) and ARTHRALGIA (worsening joint pain). In 2021, the patient experienced SPINAL STENOSIS (stenosis of back) and ALOPECIA (hair loss after covid vaccine). On an unknown date, the patient experienced MOOD ALTERED (moody). The patient was treated with CODEINE PHOSPHATE, PARACETAMOL (TYLENOL WITH CODEINE) at an unspecified dose and frequency and ALPRAZOLAM (XANAX) at an unspecified dose and frequency. At the time of the report, SPINAL STENOSIS (stenosis of back), ALOPECIA (hair loss after covid vaccine), DEPRESSION (worsening depression) and MOOD ALTERED (moody) had not resolved and JOINT SWELLING (increased swollen joint) and ARTHRALGIA (worsening joint pain) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Pain assessment: joint pain on a scale of eight out of 10. On an unknown date, Weight: Gain.         Concomitant medication was not reported.   The patient had been taking Prednisone for her Rheumatoid Arthritis on and off since she was 19. She tried dropping the dosage from 5 to 2.5 after starting Rinvoq but had to go back to 5 because she could not get out of bed when it was 2.5. There was improvement in her Rheumatoid Arthritis but that she was still having pain in her foot and elbow. She had some difficulty remembering since starting Rinvoq in February 2021. She reported a new back pain, physician was aware, since starting Rinvoq and tried tapering Prednisone 10 mg but had noticed definitely more pain. She did not take Methotrexate as it did not work for her but she was on Steroids but had been weaning herself off. She had stenosis of the back and her back had been bothering her. She reported joint pain in Mar 2021 an increase in bothersome symptoms such as new swollen joints or worsening joint pain. She took some Xanax for depression because it got so bad, she could not take it. She noticed it worsening about 3-4 months ago in Jun 2021. She wanted to know how long it took for Rinvoq to work as she did not feel any better and in fact felt like crap since she was weaning off steroids. She said her back and feet hurt. She had to take Alieve or Tylenol 3 to help with pain. She gained weight on Steroids which made back pain worse. Steroids was considered as a co-suspect. After receiving the covid vaccine, she had noticed hair loss. As of 20 Oct 2021, it seemed to be worsening. On unknown dates, the patient experienced lack of effect /steroids took for rinvoq to work as did not feel any better/felt like crap weaning off steroids and moody. It was unknown if patient was enrolled in a COVID-19 Vaccine Trial.           This case was identified as part of a retrospective clean-up activity received in the Moderna were missed to be booked-in.