crying; legs hurt; thyroid cancer; swelled her lungs and neck/lung inflammation; swelled her lungs and neck; complained of not being able to breathe; This is a spontaneous report from a contactable consumer. This consumer reported two doses for the same patient. This is the second dose. An 18-year-old female patient received the second dose of bnt162b2 (COMIRNATY) via an unspecified route of administration in Jul2021 (Lot number was not reported) as single dose for COVID-19 immunisation. Medical history included Covid 19 infection at age 17 in Jan or Feb2020 and recovered. The patient's concomitant medications were not reported. The patient previously received the first dose of bnt162b2 in May2021 at single dose for COVID-19 immunisation and experienced eyes burn. The caller stated she heard a report on public radio about super immune responders- people with a HX of Covid-19 infection who when they receive Covid-19 vaccine, they develop a super immune response (inflammation all over the body, breathing problems). Asking if we have any information on this or if we can refer her to any research programs that are studying super immune response. States she is calling on behalf of a family who has an 18 years old female child who developed covid 19 infection at age 17 in Jan or Feb2020. States covid 19 infection went right through the high school with many students developing covid 19. States this 18 years old patient recovered from covid 19 infection however when she had the Pfizer covid vaccine approximately one year later developed extreme reactions to the vaccine. States the patient developed mild reactions to the first shot but became very ill with the 2nd shot. States the 2nd shot swelled her lungs and neck; patient complained of not being able to breathe. Caller states this patient developed 'extensive issues'. States her heart was ok. She recovered with steroids. Upon transfer, the caller clarifies the patient's parents heard a segment on the Public Radio about super immune responders and the parents wanted to know if this is what happened to her daughter? The caller is an Occupational Therapist and has had extensive medical training. The caller states she does all kinds of research for families and she ran into this patient's family who asked the caller if she thought it was a super immune response. The caller explains she knows the patient and worked with the patient before so she told the patient's parents she would try and find out information and report what happened to her. The family is at a loss. The patient is better, but from what the family understood from listening to the radio, there is a study being done and there is a particular university looking for people who had a super immune response the patient's family didn't know if the patient should be in this program. The caller states she didn't know about it. The family has no idea what is going on. The caller believes the patient got her second shot in early Jul2021. The caller states she can't remember what the parents said, but she knows the pediatrician told the patient to wait however many weeks after the normal period of time before she got her second shot. The caller clarifies maybe the patient got the first shot in May, not Jun2021. She only knows the patient waited several weeks for her eyes not to burn before she got the second shot, so it would be better to put the date of the first dose as May2021. After the second shot, within 24 hours she was crying, she didn't know what was wrong. The patient said her legs hurt. The patient didn't really have a fever, but she was miserable so they started giving her Advil. This went on and on slowly and the caller guesses it started affecting her lungs and the patient started complaining of breathing problems. Her neck swelled up. The patient's pediatrician thought it was thyroid cancer and sent her for a thyroid ultrasound. The patient was just miserable. This started in the Summer so the patient was not in school. The patient was asked for a cardiac appointment and was sent for an echocardiogram. They were told the patient's heart was working correctly. She continued on Advil twice a day. The third doctor stated she really needed steroids. The patient was fine after the first dose of steroids, her lungs returned to normal. The patient experienced 60 days of miserableness. The patient was very active before the vaccine and now the patient is not as active. Her family doesn't understand what happened to her. The caller clarifies further the third doctor put her on steroids, like a tapered dose where she was taking 5, then, 4, 3, 2, 1. The first day, the patient thought she was fine. The patient is still not fully recovered. The caller ran into the patient's parents on Saturday. The caller adds she knows the family extensively and the parents explained they heard of the article on the radio and asked did the caller think their daughter is a super immune responder? She informed the family she would call Pfizer and see if she found something. The caller explains the previous agent informed the caller that it appears what she was describing was a hyperimmune response. The caller states no one treated the patient for about 60 days until the doctor put her on steroids, which seemed to stop the lung inflammation. The patient is not playing sports at the rate she was before this all happened. The caller wanted to find out where the studies for super immune responders heard on the radio were being done? The outcome of the events was not recovered.  The lot number for [bnt162b2], was not provided and will be requested during follow up