neck pain; weakness; mucous membranes are moist; goiter; skin is warm; Malaise; fatigue; chills; Sub-acute thryroiditis; fevers to 102; This spontaneous case was reported by a physician and describes the occurrence of THYROIDITIS SUBACUTE (Sub-acute thryroiditis), NECK PAIN (neck pain), ASTHENIA (weakness), MUCOSAL DISORDER (mucous membranes are moist) and GOITRE (goiter) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Cervical spondylosis in 2018, Chest pain in November 2019, Shortness of breath in November 2019, Surgery (C-Section), Surgery (bunionectomy) and Paresthesia. Previously administered products included for an unreported indication: BCG. Family history included Breast cancer (The Patient's mother had breast cancer) and Ovarian cancer (The patients sister had ovarian cancer and she is deceased.). Concurrent medical conditions included Nephrolithiasis (The patient passed kidney stones twice approximately 10 years ago) since 2011, Migraine and Postmenopausal symptoms (For over a year).   On 28-Dec-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Jan-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 27-Jan-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced PYREXIA (fevers to 102). On 28-Jan-2021, the patient experienced THYROIDITIS SUBACUTE (Sub-acute thryroiditis). On an unknown date, the patient experienced NECK PAIN (neck pain), ASTHENIA (weakness), MUCOSAL DISORDER (mucous membranes are moist), GOITRE (goiter), SKIN WARM (skin is warm), MALAISE (Malaise), FATIGUE (fatigue) and CHILLS (chills). The patient was treated with PREDNISONE for Thyroiditis, at a dose of 20 milligram once a day. On 20-May-2021, THYROIDITIS SUBACUTE (Sub-acute thryroiditis) and PYREXIA (fevers to 102) had resolved. At the time of the report, NECK PAIN (neck pain), ASTHENIA (weakness), MUCOSAL DISORDER (mucous membranes are moist), GOITRE (goiter), SKIN WARM (skin is warm), MALAISE (Malaise), FATIGUE (fatigue) and CHILLS (chills) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In May 2018, Body temperature:. In May 2018, Magnetic resonance imaging: 1.1 centimeter soft tissue lesion (abnormal) 1.1 centimeter soft tissue lesion in the left posterior nasopharynx. In May 2018, Tuberculin test:. In 2018, Magnetic resonance imaging: cervical spondylosis (abnormal) Cervical Spondylosis most significant at C5-6 with sever right sided neural foraminal narrowing. On 20-Feb-2021, C-reactive protein: 2.1 (normal) CRP 2.1 normal. On 20-Feb-2021, Red blood cell sedimentation rate: 43 (High) ESR 43 high. On 03-Mar-2021, Anti-thyroid antibody: less than 28 (normal) Thyroid peroxidase antibody less than 28 normal. On 03-Mar-2021, Blood thyroid stimulating hormone: 0.011 (Low) TSH 0.011 low. On 04-Mar-2021, Ultrasound thyroid: thyroiditis (abnormal) thyroid ultrasound was consistent with thyroiditis. On an unknown date, Body temperature: 102 (High) 102. On an unknown date, Tuberculin test: negative (Inconclusive) Negative with a minimal erythematous..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No concomitant medications were reported.  The patient had two COVID-swab test after her second dose.   In 2014 the patient underwent MRI examination of cervical spine and repeated the examination in 2018 which showed cervical spondylosis significant at C5-6.   Most recent FOLLOW-UP information incorporated above includes: On 27-Jul-2021: Patient's ethnicity, race, historical condition, family history, lab data, drug dosage regimen, treatment information, event outcome and events were added