Stage 4 advanced laryngeal cancer/ completely ravaged and this cancer was really hurting patient/as the tumor has spread to nearby lymph nodes/ had a few health problems; you can imagine my anguish and dismay; This spontaneous case was reported by a patient and describes the occurrence of LARYNGEAL CANCER STAGE IV (Stage 4 advanced laryngeal cancer/ completely ravaged and this cancer was really hurting patient/as the tumor has spread to nearby lymph nodes/ had a few health problems) in a  patient of an unknown age and gender who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On an unknown date, the patient received dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 1 dosage form. On an unknown date, the patient experienced LARYNGEAL CANCER STAGE IV (Stage 4 advanced laryngeal cancer/ completely ravaged and this cancer was really hurting patient/as the tumor has spread to nearby lymph nodes/ had a few health problems) (seriousness criterion medically significant) and ANXIETY (you can imagine my anguish and dismay). At the time of the report, LARYNGEAL CANCER STAGE IV (Stage 4 advanced laryngeal cancer/ completely ravaged and this cancer was really hurting patient/as the tumor has spread to nearby lymph nodes/ had a few health problems) and ANXIETY (you can imagine my anguish and dismay) outcome was unknown.            Concomitant and treatment medications were not reported.  The veredict fell like a wave that swept away everything in its path, you can imagine my anguish and dismay at this terrible news and the dark future that suddenly opens before me. I am completely ravaged, and this cancer was really hurting me.  The patient currently visiting a Specialist (Surgeon-Oncologist) for more detailed examinations before surgery. The doctor was honest informed patient that this type of cancer was difficult. Patient keeping this sad news confidential while waiting for the end of samples of (Biopsy) (MRI) Bone Scintigraphy, Chest Scan, Ultrasound, Hepatic, TNM classification, PET-CT and information about surgery, chemotherapy, and radiation therapy before talking about it to anyone.  Company Comment: This is a spontaneous case concerning a patient of an unknown age and gender with no reported medical history, who experienced the serious (due to medically significant) unexpected, event of Laryngeal cancer stage IV, which occurred on an unknown date in the context of a dose of mRNA-1273.222 (Original/Omicron BA.4/BA.5) vaccine. It was reported that tumor had spread to nearby lymph nodes. The patient was currently visiting a Specialist (Surgeon-Oncologist) for more detailed examinations before surgery. The doctor was honest informed patient that this type of cancer was difficult. Patient was waiting for the end of samples of (Biopsy) (MRI) Bone Scintigraphy, Chest Scan, Ultrasound, Hepatic, TNM classification, PET-CT and information about surgery, chemotherapy, and radiation therapy before talking about it to anyone; patient was anguish. No further information was disclosed. The benefit-risk relationship of mRNA-1273.222 (Original/Omicron BA.4/BA.5) vaccine is not affected by this report.