"hemorrhaging out" from her rectum/this time was the worst; "hemorrhaging out" from her rectum/this time was the worst; received second bnt162b2 on 21Jan2021; This is a spontaneous report from a Pfizer- sponsored program via a contactable consumer. An 82-year-old female patient (reporter's mother) received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration on 21Jan2021 (Batch/Lot number was not reported) as 2ND DOSE, SINGLE for covid-19 immunisation. Medical history included rheumatic fever when she was 3 years old, open heart surgery for valve repair in Feb1982, open heart surgery for mitral valve replacement with artificial valve in 1993, type 2 diabetes started coming on by 2000 but it was not adequately addressed and treated until probably 2005, Heart failure maybe had it since at least 2000 and it got worse, sepsis from an infection, lymphedema from 2011 (that was treated with a black box antibiotic which ended up destroying the balance in her brain and then she was no longer able to drive, walk without a walker or assistance from someone, and that's when the heart really became more serious with the heart failure in 2011), high blood pressure. Height: Caller says her mother may have shrunk a little bit with age. Weight: 145 to 148 pounds. Caller says for her mother's medical conditions she had rheumatic fever at age 3 and she was hospitalized for almost 3 years in a trial when they didn't have a treatment. They finally put her in the Hospital for 6 months and gave her penicillin shots every week and she was told to have no physical activity until she was 18 years old and then they stopped the penicillin shots and they didn't anticipate that she would live long. So she has always had trauma from that to her heart. Concomitant medication included warfarin sodium (COUMADIN) from 1982 and ongoing for blood thinner. The patient previously received the first single dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE) on 07Jan2021 for covid-19 immunisation. Caller reported that while she has had hemorrhoids in her history and has unaddressed issues found in a colonoscopy, on 09May2021 in the morning her mother experienced "hemorrhaging out" from her rectum causing her to be admitted to the hospital. Reporting that she was just released on 17May2021. Caller vocalizes concern that, because her mother required blood transfusions during her hospitalization, the vaccine efficacy may have been affected and she asks if given her mothers situation, she should get an additional dose of the vaccine? During this call she mentioned that both of her parents received both doses of the vaccine and experienced none of the common side effects. Caller states that her mother was hemorrhaging blood and when she was at the hospital they immediately got her on blood. The caller is unsure if the blood was originally received in the ambulance or in the hospital. When she got to the hospital her hemoglobin was 8 and they did a blood transfusion and she got 2 bags of blood. Event Details: On 09May2021, her mother began hemorrhaging at that point and she had tried to go to the bathroom because she felt like she was going to leak more and when she had went to the bathroom, which is not a long distance maybe about 6 feet, at the entrance of the bathroom her mother described it as she couldn't hold it and blood poured out of her. This has been an ongoing issue that her mother has neglected to take care of by getting a colonoscopy for the past 4 years and she has been bleeding all this time but never to this extent. The caller didn't think that her father realizes how close she was to death. Caller confirmed that her mother has been bleeding since before the COVID vaccine but it was nowhere near as bad as this, this time was the worst. For the past month or so her Coumadin levels have been going up and down and her bloodwork was not coming back right away and her primary care provider, mentioned above, hasn't done much for this. For the caller and her mother it is very discouraging. If her mother saw the heart doctor then all of this probably could have been prevented and if the blood thinner was working correctly. They have dealt with all of that at Hospital but her mother puts things off, she is stubborn. The caller thinks that the lengthy hospital stay and being so close to death maybe scared her mother a bit. The only thought was that her mother's blood thinner hasn't been balanced correctly for the past month and that was something that was concerning but her doctor, wasn't taking it very seriously. Her mother has been on Coumadin for a long time and when they did see her and did the bloodwork it showed that her blood thinner was extremely too high and that would explain why this episode of bleeding was so much worse than the previous ones. The outcome of the events was unknown.   Information on the lot/batch number has been requested.