itching due to hives and rash; hives and rash came back this morning about 10 minutes after waking up and is "all over body"; forearms, back of hands and wrists broke out in hives and rash/ hives and rash came back this morning about 10 minutes after waking up and is "all over body"; severe right shoulder pain; pain that radiated down right arm which was opposite side from where vaccine was administered; migraine; neck pain of both sides; This spontaneous case was reported by a consumer and describes the occurrence of PAIN IN EXTREMITY (pain that radiated down right arm which was opposite side from where vaccine was administered), MIGRAINE (migraine), NECK PAIN (neck pain of both sides), PRURITUS (itching due to hives and rash) and URTICARIA (hives and rash came back this morning about 10 minutes after waking up and is "all over body") in a 53-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 038A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Histamine intolerance.    On 24-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 24-Mar-2021, the patient experienced PAIN IN EXTREMITY (pain that radiated down right arm which was opposite side from where vaccine was administered), MIGRAINE (migraine), NECK PAIN (neck pain of both sides) and ARTHRALGIA (severe right shoulder pain). On 31-Mar-2021, the patient experienced PRURITUS (itching due to hives and rash), URTICARIA (hives and rash came back this morning about 10 minutes after waking up and is "all over body") and RASH (forearms, back of hands and wrists broke out in hives and rash/ hives and rash came back this morning about 10 minutes after waking up and is "all over body"). The patient was treated with PARACETAMOL (TYLENOL) at an unspecified dose and frequency and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) at an unspecified dose and frequency. On 25-Mar-2021, PAIN IN EXTREMITY (pain that radiated down right arm which was opposite side from where vaccine was administered), MIGRAINE (migraine), NECK PAIN (neck pain of both sides) and ARTHRALGIA (severe right shoulder pain) had resolved. At the time of the report, PRURITUS (itching due to hives and rash) outcome was unknown and URTICARIA (hives and rash came back this morning about 10 minutes after waking up and is "all over body") and RASH (forearms, back of hands and wrists broke out in hives and rash/ hives and rash came back this morning about 10 minutes after waking up and is "all over body") had not resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       Concomitant medication included allergy pills and occasional vitamins. On 31-Mar-2021 in the morning patient reported that forearms, back of hands and wrists broke out in hives and rash which was itchy. She took Benadryl which helped but stated the hives and rash returned in the evening. On 1-Apr-2021 morning, the hives and rash came back about 10 minutes after waking up and was all over body. She stated that there was hives and rash on thighs and belly which was itchy.