hair has gradually become curly/her hair has been straight; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program. The reporter is the patient.  A 85 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in arm, administration date 09Mar2021 (Lot number: EN6206) at the age of 84 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Miscarriage", start date: 1959 (unspecified if ongoing); "Vaginal delivery" (unspecified if ongoing), notes: Birth of five children vaginal deliveries - 1960, 1961, 1963, 1969, 1970 -Normal Vaginal deliveries, Birth of sixth child 1972 - normal vaginal delivery; "Cholecystectomy", start date: 1990 (unspecified if ongoing); "Hysterectomy", start date: 1993 (unspecified if ongoing); "Cataract removal, bilateral", start date: 2012 (unspecified if ongoing); "Emergency incarcerated umbilical hernia repair", start date: 2016 (unspecified if ongoing); "Insertion of pacemaker", start date: Jan2018 (unspecified if ongoing); "Pnuemonia/congestive heart failure", start date: Oct2020 (unspecified if ongoing); "Vein stripping, Left leg", start date: 1971 (unspecified if ongoing); "T & A", start date: 1941 (unspecified if ongoing); "D&C - conization", start date: 1959 (unspecified if ongoing); "Pneumonia/congestive heart failure", start date: Oct2020 (unspecified if ongoing); "macular degeneration" (unspecified if ongoing), notes: Before vaccine. Concomitant medication(s) included: LEVOTHYROXINE taken for thyroid disorder (ongoing); CARVEDILOL taken for blood pressure abnormal (ongoing); LISINOPRIL taken for blood pressure abnormal (ongoing); FUROSEMIDE (ongoing); POTASSIUM (ongoing); ISOSORBIDE MONONITRATE (ongoing); SIMVASTATIN taken for blood cholesterol abnormal (ongoing); ALPRAZOLAM (ongoing); ASPIRIN LOW (ongoing); VITAMIN D [COLECALCIFEROL]. Vaccination history included: Bnt162b2 (Dose: 1, Administration Date: 16Feb2021, Anatomical site of Injection: arm, Route of administration: Intramuscular, Batch/Lot number: EN6201), administration date: 16Feb2021, when the patient was 84 years old, for Covid-19 immunization. The following information was reported: HAIR TEXTURE ABNORMAL (non-serious) with onset Mar2021, outcome "unknown", described as "hair has gradually become curly/her hair has been straight". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: The patient received I-CAPS vitamin (multivitamin for her eyes). The patient gave birth of five children vaginal deliveries in 1960, 1961, 1963, 1969, 1970 (normal vaginal deliveries). Birth of sixth child 1972 normal vaginal delivery. It was reported that, the patient's hair had gradually got curly. She can't tell for sure if it began after the first or second dose. It has been very gradual. It has continued to increase in its weight. No prior vaccinations received (within 4 week). No concomitant drugs taken within two weeks before the event onset. No other diagnostic and confirmatory test results done. No specific relevant test done for thromboembolic events with thrombocytopenia. The patient reported that she could not think of anything that could have caused this other than the COVID injections. She had not visited a beauty salon in months. She did not use a curling iron or a blow dryer. She had been taking several medications, but they were all things that she had taken for quite a while, and she had started no new medications.  No follow-up attempts are possible. No further information is expected.