Seizures similar to partial grand mal and grand mal seizures; Full COVID-19 symptoms; High fever; Difficulty breathing/ Shortness of breath; Cough; Chills; Extreme head pain; Extreme body aches; Brain fog; Inability to follow conversation or form sentences; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 29-year-old female patient (not pregnant) received BNT162B2 (BNT162B2), administered in arm left, administration date 26Oct2021 18:45 (Lot number: 320308D) at the age of 29 years as dose 1, single for COVID-19 immunization. Relevant medical history included: "COVID-19", start date: Feb2020 (unspecified if ongoing). The patient's concomitant medications were not reported. The patient did not receive any other vaccines within 4 weeks prior to the COVID-19 vaccine. The following information was reported: GENERALISED TONIC-CLONIC SEIZURE (disability, medically significant, life threatening) with onset 27Oct2021, outcome "recovering", described as "Seizures similar to partial grand mal and grand mal seizures"; SUSPECTED COVID-19 (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Full COVID-19 symptoms"; PYREXIA (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "High fever"; DYSPNOEA (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Difficulty breathing/ Shortness of breath"; COUGH (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Cough"; CHILLS (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Chills"; HEADACHE (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Extreme head pain"; PAIN (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Extreme body aches"; FEELING ABNORMAL (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Brain fog"; COMMUNICATION DISORDER (disability, life threatening) with onset 27Oct2021, outcome "recovering", described as "Inability to follow conversation or form sentences". The events "seizures similar to partial grand mal and grand mal seizures", "full covid-19 symptoms", "high fever", "difficulty breathing/ shortness of breath", "cough", "chills", "extreme head pain", "extreme body aches", "brain fog" and "inability to follow conversation or form sentences" were evaluated at the physician office visit and emergency room visit. Therapeutic measures were taken as a result of generalised tonic-clonic seizure, suspected covid-19, pyrexia, dyspnoea, cough, chills, headache, pain, feeling abnormal, communication disorder. Clinical course: Adverse reactions occurred to first shot. Seizures similar to partial grand mal and grand mal seizures, and also full COVID-19 symptoms including high fever, difficulty breathing, cough, chills, extreme head pain, extreme body aches, shortness of breath, brain fog, inability to follow conversation or form sentences. Already had COVID-19 in Feb2020, with antibodies in T-cells, prior to vaccination. Seizures continued multiple times a day for nearly 3 weeks, then decreased. The patient received the second dose in the right arm on 18Nov2021 18:30 (lot number: 3302680).  No follow-up attempts are possible. No further information is expected.