sinus pressure; menstrual irregularities; experiencing all the premenstrual symptoms I described: pimples; experiencing all the premenstrual symptoms I described: irritable; just queasy nausea; experiencing all the premenstrual symptoms I described: felt bloated; experiencing all the premenstrual symptoms I described: premenstrual cramps; experiencing all the premenstrual symptoms I described: miserable; Lymph edema; premenstrual symptoms; teeth hurt; my teeth hurt, they are extremely sensitive to temperature (hot or cold); I feel chills, which I do not have a fever, but I feel like I have fever; cough; fatigued; fever; bullseye headache; This is a spontaneous report received from a contactable reporter(s) (Other HCP) from medical information team. The reporter is the patient.  A 52 year-old female patient received bnt162b2 (COMIRNATY), administration date 27Nov2021 (Lot number: FG3527) at the age of 52 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "COVID-19", start date: 01Dec2020, stop date: 01Dec2020, notes: I had COVID one year ago December first 2020. Concomitant medication(s) included: VITAMINS NOS. The following information was reported: TOOTHACHE (non-serious), outcome "unknown", described as "teeth hurt"; HYPERAESTHESIA TEETH (non-serious), outcome "unknown", described as "my teeth hurt, they are extremely sensitive to temperature (hot or cold)"; CHILLS (non-serious), outcome "unknown", described as "I feel chills, which I do not have a fever, but I feel like I have fever"; COUGH (non-serious), outcome "unknown", described as "cough"; FATIGUE (non-serious), outcome "unknown", described as "fatigued"; PYREXIA (non-serious), outcome "unknown", described as "fever"; HEADACHE (non-serious) with onset 27Nov2021, outcome "not recovered", described as "bullseye headache"; PARANASAL SINUS DISCOMFORT (non-serious), outcome "unknown", described as "sinus pressure"; MENSTRUATION IRREGULAR (non-serious), outcome "unknown", described as "menstrual irregularities"; ACNE (non-serious), outcome "unknown", described as "experiencing all the premenstrual symptoms I described: pimples"; IRRITABILITY (non-serious), outcome "unknown", described as "experiencing all the premenstrual symptoms I described: irritable"; NAUSEA (non-serious), outcome "unknown", described as "just queasy nausea"; ABDOMINAL DISTENSION (non-serious), outcome "unknown", described as "experiencing all the premenstrual symptoms I described: felt bloated"; PREMENSTRUAL PAIN (non-serious), outcome "unknown", described as "experiencing all the premenstrual symptoms I described: premenstrual cramps"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "experiencing all the premenstrual symptoms I described: miserable"; LYMPHOEDEMA (non-serious), outcome "unknown", described as "Lymph edema"; PREMENSTRUAL SYNDROME (non-serious), outcome "unknown", described as "premenstrual symptoms". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of toothache, hyperaesthesia teeth, chills, cough, fatigue, pyrexia, headache, paranasal sinus discomfort, menstruation irregular, acne, irritability, nausea, abdominal distension, premenstrual pain, feeling abnormal, lymphoedema, premenstrual syndrome.  Additional information: I am a premenopausal 52 year old woman. I'm very healthy: I'm active, I'm not a smoker, I don't drink alcohol and I exercise regularly. On 01Dec2020 I had COVID-19 infection that lasted from 6 to 7 weeks, within weeks I ended up getting a cycle again and I experienced 1 or 2 cycles, I had all the premenstrual symptoms: I broke out [pimples], I was irritable, I experienced nausea, felt bloated, experienced premenstrual cramps and overall I felt miserable. On 27NOV2021 I received my first dose on the Pfizer BioNTech COVID-19 vaccine adult formulation (purple cap) and since the I have not felt right since then: my teeth hurt, they are extremely sensitive to temperature (hot or cold). I even have tooth pain in a tooth that does not even have a root anymore I have not changed my paste or any other factors that may be causing this situation. I have chills, cough I feel fatigued, I had experienced fever as well. I've had a bullseye headache that has not gone away since then and sinus pressure since I got the vaccine. Some hours are worse than others. I have not had a menstrual cycle for over a year now (since my COVID-19 infection), but I'm experiencing all the premenstrual symptoms I described previously [when I had a COVID-19 infection] I consider my symptoms to be hormone related. I have not felt well since, I do not know how much of the adverse reaction, I have never reported any adverse reaction before for myself, first of all, so, 27Nov2021 I have had a headache, both eyes like right between my eyes, the bridge of my nose, seems basically the end of  the first day, it does not go away, nausea, not vomiting, just queasy nausea, every single day, at least multiple time of the day, I feel chills, which I do not have a fever, but I feel like I have fever, I have a cough, I am COVID negative, multiple negative COVID test, basically all of my COVID symptoms because I have had COVID, I had COVID one year ago 01Dec2020 (my COVID symptoms started so, I have got the cough, I have got the headache, I have got the fatigue, but the more important part of this, that I find no body is discussing and I am noticing for my self is that I have been, I guess pre-menopausal, because I have been without a cycle not quite a year yet but approaching a year and I am getting like hormonal symptoms). I am 52 years old so, I know my body very well, I am now breaking up with pimples, I got them on my chin, I have got them on my cheeks, I have got them on my throat and I have got them everywhere and I do not get pimples. Patient further stated, "I have got menstrual cramps and headache, I would describe it as the type of headache that I would get just prior to having a menstrual cycle so, whenever you would ask me right now I would say, I feel like I am about to get my period, those are the symptom that I have, with the addition of a cough. Prior to getting with vaccine, I was completely fine. There was nothing wrong with me. When I had COVID a year ago I was same thing without a cycle months and months no cycle no sign of cycle, within a month of getting COVID my cycle resumed and it resumes for about a short period of time and then stop. I find it really odd but after getting the first shot, I am starting to feel like I am going to start a cycle again. I mean it's just really weird and I am very 'into' my body just because I have just been that way. I have been for a lot of years so, I know what is not normal, how I have been feeling since I got the shot is not normal. Treatment taken: patient stated, Yes. So, I have been taking Advil alternating with Tylenol. Other Vaccine (Prior to 4 weeks of COVID Vaccine): patient stated no. Patient stated, "I got the vaccine on the left deltoid and I will also tell you to add lymph edema, pretty bad in the axle which one up offered to my left side and you know what, I am forgetting a couple of thing, teeth pain. So all of my teeth started hurting me, they were sensitive to hot and cold and I have the lymph edema, which I know was mentioned somewhere so, I do not know if that is an adverse effect but surely my teeth should not be hurting me.     No follow-up attempts are possible. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101771852 Same reporter/drug, different patients.;US-PFIZER INC-202101771853 Same reporter/drug, different patients.