POTs; chronic fatigue syndrome; Depression; fibromyalgia pain; chest pain; weak limbs, stiffening of his muscles and fascia; chronic pain syndrome; air obstruction interfering with sleep; panic attacks; focus and memory problems; emotional and psychological changes; agoraphobia; cold hands and feet; loss of feeling in his hands and feet; dry eyes; The neurological deficits; weak limbs, stiffening of his muscles and fascia; Irlen Syndrome; Autoimmune Disease; Autonomic Dysfunction; muscle spasms; severe allergic reaction; Plaintiff can no longer eat like he used to as certain foods trigger severe and deadly reactions; This initial spontaneous report was received on from a lawyer regarding a case in litigation and refers to a 30-years-old male patient. The patient's concurrent conditions, medical history and concomitant medication were not provided.   On 03-JUL-2019, the patient was vaccinated with a first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL) (Lot #, expiration date, dose, route of administration and anatomical location of vaccine were not provided) both for preventing cervical cancer.  On 12-JUL-2019, nine days subsequent to the patient vaccination, the plaintiff was rushed to a nearby Urgent Care facility and injected with a steroid to stop the closing of his airways due to a severe allergic reaction. At the time, he also suffered swollen lips, throat closure, airway constriction, difficulty breathing, hives and profuse sweating. In July 2019, plaintiff was having severe allergic reactions to foods which he did not have issues eating before his first quadrivalent human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL) injection. For the next several months, Plaintiff suffered multiple severe reactions to foods. His primary care physician referred Plaintiff to an allergy specialist who concluded that Plaintiff would now need to always carry an Epinephrine pen in his pocket due to the severity of what was understood at the time to be sudden onset severe allergic reactions.  On 16-SEP-2019, with the second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL). After received the second dose, Plaintiff's complaints worsened. In addition to his severe allergic reactions, Plaintiff experienced increased anxiety and muscle spasms and required neurological consultation. The neurological deficits, allergic reactions, and spasms interfered with his ability to work.   Additionally, based upon her chronic and severe post-Gardasil symptoms, Plaintiff has been diagnosed with various medical conditions, including, but not limited to, autonomic dysfunction and has Resulted in Her Suffering from Severe, Debilitating, Disabling and Painful Chronic Injuries. At the reporting time, the outcome of the event was unknown. As the months progressed, so did Plaintiff's injuries. He was seen by multiple physicians and specialists for his complaints which now included: loss of feeling in his hands and feet, cold hands and feet, vision problems, focus and memory problems, severe allergies, anxiety, emotional and psychological changes, depression, agoraphobia, coordination issues, dry eyes, vertigo, headaches, balance problems, shortness of breath, airway closure, difficulty breathing, weak limbs, stiffening of his muscles and fascia, chronic pain syndrome, chronic fatigue syndrome, intense muscle spasms, inability to focus on day-to-day tasks, fibromyalgia pain, chest pain, air obstruction interfering with sleep, panic attacks, poor concentration, and intense pain in his legs and arms. As a result of his post-Gardasil symptoms, Plaintiff was unable to engage in normal activities that a normal young person would enjoy. Plaintiff has been unable to work since September 2019, he was recently diagnosed with Irlen Syndrome, and he was living with his parents for support. Plaintiff can no longer eat like he used to as certain foods trigger severe and deadly reactions. Plaintiff continued to suffer from the above described neurological, autonomic and autoimmune injuries. Based upon his chronic and severe post-Gardasil symptoms, Plaintiff had been diagnosed with various medical conditions, including but not limited to, Irlen Syndrome, chronic fatigue syndrome, severe allergies, depression, and anxiety. Plaintiff contends that his human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL) injection(s) caused him to develop serious and debilitating injuries, including but not limited to autonomic, neurological, heterogenous autoimmune disease, POTS, and dysautonomia, as well as a constellation of adverse symptoms, complications, injuries, and/or other adverse events, many of which are alleged herein and all of which were caused by human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL) or otherwise linked to his Gardasil-induced autoimmune disorder  The reporter considered the events of shingles to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. Vaccine (GARDASIL).  Upon internal review the event of Autoimmune Disease, food allergy and hypersensitivity were considered as medically significant.