schizophrenia; Psychosis; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP), Program ID: (Unknown). The reporter is the parent.  A 27-year-old male patient received BNT162b2 (BNT162B2), on 16Mar2021 as dose 1, single (Lot number: EN6207) at the age of 27 years for covid-19 immunisation. The patient's relevant medical history included: "Peanut allergy" (unspecified if ongoing); "Anxiety" (unspecified if ongoing); "Nightmare" (unspecified if ongoing). The patient took concomitant medications.  The following information was reported: PSYCHOTIC DISORDER (medically significant) with onset 11Apr2021, outcome "unknown", described as "Psychosis"; SCHIZOPHRENIA (medically significant), outcome "unknown". The event "psychosis" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Blood test: Unknown results, notes: Her son had one MRI without contrast and blood work; Gene test: none of the medicines he was on have been good, notes: none of the medicines he was on have been good for him because he doesn't metabolize the medication effectively; Magnetic resonance imaging: Unknown results, notes: Her son had one MRI without contrast and blood work. Therapeutic measures were taken as a result of psychotic disorder.   Clinical course: Date of first psychosis was 11Apr2021. On 11Apr2021 he went to ER with symptoms of paranoia and psychosis. Antipsychotic Medication: he gets injection once a month. Caller has been pleading him to stay on it until they figure it out. Caller doesn't want to see him having psychosis. He did have a gene type test done. That test showed that none of the medicines he was on have been good for him because he doesn't metabolize the medication effectively so there are very few that are ok for him. What he is on now, the antipsychotic, he should be ok on it. The gene type test tells them that. That is why the ones he was on in the past weren't working for him. Caller clarified the medication her son was on in the past as Abilify and antidepressants. The doctor said she never saw someone that doesn't metabolize the medicine correctly. Her son did go for second opinion. Caller has been talking to people. The nurse at the acute care mentioned another girl about caller's son's age had the scenario after the COVID-19 vaccine. Someone else said the same thing. There are some cases, but caller doesn't know how many. Her son is not the first case this has happen to. Caller Doesn't know the girl patient. Caller wished she did know the girl so she could ask what that girl is doing to help her. Caller doesn't know how long her son can stay on the medicine and if he can get back to work. He went to # school and he worked in kitchen with knives. Caller doesn't know if he is capable of doing that. This is a problem. Caller has researched other cases online that this has happened to. What is Pfizer doing and what can be done now? It is very upsetting for her to talk about. Caller has problems talking with her jaw. Caller declined transfer. Caller clarified that she can't remember the name of the antipsychotic medication and doesn't have a LOT number to provide. Concomitant Medication: None. He didn't take medication, he only took vitamins previously. Investigations: he has been getting blood work and the new doctor wants to get an MRI with contrast. There are a lot of red flags that don't match. Her son is too old to have schizophrenia at 27 or 28 without having any other psychosis. The doctor wants to see what his brain looks like to see if it looks environmental. There are 3 ways to have psychosis. Her son had one MRI without contrast and blood work. Pfizer/BioNTech COVID-19 Vaccine Follow-up Questionnaire. Vaccination Facility Type: Convention Center. Her son got the vaccine because he was in food service. He wanted to keep customers safe. Vaccine Administered at Military Facility? No.  Prior Vaccinations (within 4 weeks): none. Family Medical History Relevant to Adverse Events (AEs): None, and that is why it raises a red flag. Specific Relevant Test: For Thromboembolic events with Thrombocytopenia: N/A. Emergency Room: Yes