SHORTNESS OF BREATH; CHEST PAIN; SLEEP DOESN'T GET BETTER; BURNING BOTH LEGS; CHILLS ALL OVER; TINGLING ON BOTH  ARMS AND LEGS; NUMBNESS OF BOTH LEGS; MULTI MYALGIA RHEUMATICA; HAIR LOSS; BODY ACHE ALL OVER; HEADACHE; This spontaneous report received from a patient concerned a 57-year-old female. The patient's height, and weight were not reported. The patient's concurrent conditions included: high blood pressure (currently on medication), alcohol user, non-smoker, and pre-diabetes, and other pre-existing medical conditions included: The patient did not have any known drug allergies. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, intramuscular, batch number: 1802070 expiry: Unknown) frequency one total, dose was not reported, vaccinated on right arm on 13-MAR-2021 for prophylactic vaccination.(dose number in series 1) Concomitant medications included clobetasol. The Patient called after receiving Janssen vaccine on 13-MAR-2021, On an unspecified date in month of march She had chest pain and shortness of breath; She had to go to emergency room with chest pain and shortness of breath 2 more times. In ER checked for stroke and blood clots but "everything was fine" They did Computerized tomography Scan, and they did not find anything. "They sent her to see the doctor" "Before when she had headache and chills they said to see her neurologist, and they send to do tests, As per the patient she received therapy, but the pain did not go away. She felt little better than before but when she took the booster then the symptoms start again" "Finally they put the patient on medication" .The hair loss started in August, one day she woke up without hair on one side. She went to the dermatologist, and he ordered a biopsy and result not provided ,he gave me Clobetasol and changed the cream after one and half months he changes it to a different cream." The patient said the name of the new cream was Augmentin, but the company representative explained that is an oral antibiotic, so it is not clear what the name of the new cream is.  On 25-Nov-2021 she experienced multi myalgia rheumatica and called she called her primary doctor and asked him to prescribe high dose prednisone and her primary doctor says she had to take for the rest of her life. She had an appointment next month to see him again". She did not have cough and fever.( all events occurred in dose number in series 1) The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from shortness of breath, and chest pain on 03-JAN-2022, was recovering from headache, body ache all over, and hair loss, and had not recovered from tingling on both arms and legs, tingling on both hands, numbness of both legs, chills all over, burning both legs, and multi myalgia rheumatica. The patient received non company suspect Pfizer (BNT 162) (route of information was not reported batch number: FJ8757 expiry: Unknown) dose was not reported, vaccinated on left arm on 9-Dec-2021 for prophylactic vaccination (Dose number in series 2) After booster vaccination, she again experienced tingling on both arms and legs and both hands, her sleep doesn't get better" she did not sleep because of pain.  The action taken with Pfizer (BNT 162) was not applicable. The outcome of hair loss and sleep doesn't get better, tingling on both arms and legs, tingling on both hands  was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: 20220102657-covid-19 vaccine ad26.cov2.s-multi myalgia rheumatica. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).