severe limp nodes, swelling/had 3 lymph nodes, and an other  that can't be seen; his arm got sore; HE THINKS THE SHOT WAS GIVING TO HIGH, AT THE PLACE OF INJECTION AND ALL AROUND AREA; on May2022 he got cancer in the throat.; This spontaneous case was reported by a patient and describes the occurrence of THROAT CANCER (on May2022 he got cancer in the throat.) in a 66-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 049L21A and 066F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Food allergy, Dairy intolerance, Food allergy and Food allergy.   On 22-Dec-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 02-May-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In May 2022, the patient experienced THROAT CANCER (on May2022 he got cancer in the throat.) (seriousness criterion medically significant). On an unknown date, the patient experienced LYMPHADENOPATHY (severe limp nodes, swelling/had 3 lymph nodes, and an other  that can't be seen), PAIN IN EXTREMITY (his arm got sore) and PRODUCT ADMINISTERED AT INAPPROPRIATE SITE (HE THINKS THE SHOT WAS GIVING TO HIGH, AT THE PLACE OF INJECTION AND ALL AROUND AREA). At the time of the report, THROAT CANCER (on May2022 he got cancer in the throat.), LYMPHADENOPATHY (severe limp nodes, swelling/had 3 lymph nodes, and an other  that can't be seen) and PAIN IN EXTREMITY (his arm got sore) had not resolved and PRODUCT ADMINISTERED AT INAPPROPRIATE SITE (HE THINKS THE SHOT WAS GIVING TO HIGH, AT THE PLACE OF INJECTION AND ALL AROUND AREA) outcome was unknown.            No concomitant medication was reported.  It was reported that symptoms had progressively worsened.  Patient reported that lymph nodes were going to look cancerous and could be a false positive;  they had not found any cancer cells in.  No treatment medication was reported;  it was mentioned that he was getting ready for chemotherapy and radiation.  Company Comment: This spontaneous case reported by a patient concerns a 66-year-old male patient, with no relevant medical history, who experienced unexpected, serious (medically significant) event throat cancer, on the same month as vaccination with a fourth dose of mRNA-1273.  He also reported severe lymph node swelling that were going to look cancerous but could be a false positive as cancer cells have not been found in them.  Further clinical course of the throat cancer, diagnostic evaluation, and concomitant medications were not reported.  No treatment reported; it was mentioned that he was getting ready for chemotherapy and radiation.  The benefit risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2021-186718, MOD-2021-186664 (Patient Link).; Sender's Comments: This spontaneous case reported by a patient concerns a 66-year-old male patient, with no relevant medical history, who experienced unexpected, serious (medically significant) event throat cancer, on the same month as vaccination with a fourth dose of mRNA-1273.  He also reported severe lymph node swelling that were going to look cancerous but could be a false positive as cancer cells have not been found in them.  Further clinical course of the throat cancer, diagnostic evaluation, and concomitant medications were not reported.  No treatment reported; it was mentioned that he was getting ready for chemotherapy and radiation.  The benefit risk relationship of mRNA-1273 is not affected by this report.