started to have hives all over her body, extra over in chest and stomach area; It was so kind of itching this morning; Had little pain in side and they had been run for kidney; whole body ache  mostly like her joints specially in her hips an her knee; she was groggy  almost like entire day , sinus thing was going on; she was groggy  almost like entire day , sinus thing was going on; her lymph node on her left arm was very swollen like for three days and before it finally went away; This is a spontaneous report from a contactable consumer (patient). This case is for 2nd dose. This case is split from AER# 2021552445 (BNT162B2, 1st dose). A 23-year-old female patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) (Lot Number: EW0167), at the age of 23-year-old, via an unspecified route of administration, administered in Arm Left on 09May2021 at single dose for COVID-19 immunisation. Medical history included dormant asthma when she was kid. The patient received unspecified concomitant medications for birth control. The patient previously received the first dose of BNT162B2 (Lot number: EW0169), at the age of 23-year-old, via an unspecified route of administration, administered in Arm Left, on 18Apr2021 for COVID-19 immunization. The patient reported that she had been having some vaccine reaction she believed, but she went to the doctor today and they believed it to an environmental reaction but, she got the vaccine on Sunday, the evening before around 11 pm, she started to have hives all over her body, extra over in chest and stomach area and then she called registered doctor provider. They told me to take antihistamine so, took two diphenhydramine hydrochloride (BENADRYL) and the last night around 11 o' clock it came back  still like around 24 hours and she took couple of more diphenhydramine hydrochloride (BENADRYL) and it was so kind of itching this morning, she took one more, but she was concern she went to the doctor, they said she reported these kind of symptoms. She had like reaction before (further clarification unknown) but this probably the most severe but she didn't believe that was an environmental was just the correlation between she getting the vaccine. Today when she went to the doctor, she had little pain in side and they had been run for kidney but like she didn't know that's the most recent one but she had other lab test in the past. She couldn't possible giving. It was reported that the diphenhydramine hydrochloride (BENADRYL) had made the hives go away but they usually like came back later in the night (further clarification unknown). The patient also received cetirizine hydrochloride (ZYRTEC) for the events. Consumer added, "they have since gone away but she had more symptoms day after when she received the vaccine. The day after woke up with whole body ache mostly like her joints specially in her hips an her knee and she was groggy almost like entire day , sinus thing was going on and her lymph node on her left arm was very swollen like for three days and before it finally went away." Event onset date was May2021. Treatment received for the events. The events resulted in Physician Office Visit. The outcome of the event hives was unknown, of the event swollen lymph nodes was recovered in May2021, of other remain events was recovering.