shortness of breath; chest pain; fatigued; after this vaccine she cannot play that well; This is a spontaneous report received from a contactable reporter(s) (Physician) from medical information team.  A 15-year-old female patient received BNT162b2 (BNT162B2), on 01Oct2021 as dose 2, 0.3 ml single (Lot number: 30135BA, Expiration Date: 30Nov2021) at the age of 13 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Knee Pain" (unspecified if ongoing), notes: Last time saw patient was Jun2021 when she went in from knee pain, from playing soccer.; "Broken arm" (unspecified if ongoing), notes: Did go to ER Nov, due to broken arm, year not provided.; "echo" (unspecified if ongoing), notes: Father has mitral valve problems, probably something to do with them doing echo for patient. The patient's family history included: "migraine headaches" (unspecified if ongoing), notes: Mom has migraine headaches, thyroid disease, allergies. "Thyroid disease" (unspecified if ongoing), notes: Mom has migraine headaches, thyroid disease, allergies. "allergies" (unspecified if ongoing), notes: Mom and Father have allergies.; "high cholesterol" (unspecified if ongoing), notes: Father has high cholesterol, "mitral valve problems" (unspecified if ongoing), notes: Father has mitral valve problems, probably something to do with them doing echo for patient. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, single, Lot: FF2588-BEL, 30mcg per 0.3ml dose, Anatomical Location: left arm), administration date: 10Sep2021, when the patient was 13-year-old, for COVID-19 IMMUNIZATION, reaction(s): "shortness of breath", "chest pain", "fatigued".  The following information was reported: DYSPNOEA (non-serious), outcome "not recovered", described as "shortness of breath"; CHEST PAIN (non-serious), outcome "not recovered"; FATIGUE (non-serious), outcome "not recovered", described as "fatigued"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious), outcome "unknown", described as "after this vaccine she cannot play that well". The events "shortness of breath", "chest pain" and "fatigued" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of dyspnoea, fatigue. Therapeutic measures were taken as a result of chest pain.  Additional information: She wanted to know if there is any suggestions if a patient is still experiencing shortness of breath, chest pain and being fatigued after getting 2 doses of the vaccine over a year and a half ago in 2021. She stated it happened shortly after the vaccine was administered. The first time was few days after the first dose and she complained of fatigue and shortness of breath and chest pain. They sent her for an echocardiogram and that was all normal and within 2 weeks she started to feel better and all of her symptoms resolved. Shortly after the second dose all of the symptoms came back and have never really gone away. She is very athletic, plays soccer year round and plays 95% of the game and never gets short of breath but now after this vaccine she cannot play that well or that long without having symptoms. They have seen so many specialists and still don't have any answers. They believe in the vaccine but they just want her back to normal. The physician asked if Pfizer has seen a lot of this and where can they go next as far as a specialist. It was stated that, this actually started in 2021. Patient was 13 years old at that time. 4 days later, called office, stating she was experiencing shortness of breath and was very fatigued. Assumed the fatigue and shortness of breath was from Covid but patient is an athlete and plays soccer yearly. Probably plays 95 percent of the games. This all was shortly after the Covid vaccine. They did some tests, echocardiogram, all were normal. Just gave her a little time get rest and not play sports. It did go away. Then, got booster 01Oct2021 (as reported), symptoms persisted. Basically, she was very tired, chest pain came back and shortness of breath along with it. Did pulmonary function test, saw the cardiologist, did EKG, stress test, all normal. Initially thought there was some vocal cord dysfunction, they did some Physical therapy exercises. All proven unhelpful, patient continued to have symptoms. Here they are a year and a half later. They still don't have any answers. She still gets very short of breath, and a little chest pain. Not quite sure who started her on it but, she saw a specialist who started her on Gabapentin for chest pain. Thought it was more muscular than anything. It had not been very helpful either. Mom is now calling caller, not quite sure who to get patient to go see. Not sure if it was the Covid vaccine but it was a coincidence that symptoms started after the Covid vaccine and got worst after the booster (as reported). Weight: At the time this started in 2021, she was 115 pounds. Height: In Dec2021, when patient came for wellness check, she was 62 inches. Thought this is the first time this is being reported with Pfizer. Does not think any of the specialists have reported it. When she came back, they thought they were not giving her booster but she felt good by the time she got the booster. Treatment: No, the only thing they did was an Echo test back in Sep2021, and just told her to rest. Clarified that when caller was previously referring to patient having booster dose, it was the patient's second dose of the Covid vaccine. Clarifying that patient has only had 2 doses Covid vaccine. Last time saw patient was Jun2021 when she went in from knee pain, from playing soccer. Nothing since then. Pulmonary function tests were normal, cardiology did stress test that was normal. Thinks when they did stress test, patient got shortness of breath but, her heart was fine. Vaccination Facility was Doctor's Office. No prior vaccination, this was the only one in 2021. Sender's Comments: Linked Report(s): US-PFIZER INC-202300148421 same patient/event, different dose.