sleeps all night and when he wakes up he does not feel refreshed/feels like he was a walking zombie; numbness from his elbows down to his hands/numbness from his knees down to his feet; felt fatigue/chronic fatigue; This spontaneous case was reported by a consumer and describes the occurrence of FEELING ABNORMAL (sleeps all night and when he wakes up he does not feel refreshed/feels like he was a walking zombie), HYPOAESTHESIA (numbness from his elbows down to his hands/numbness from his knees down to his feet) and FATIGUE (felt fatigue/chronic fatigue) in a 52-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 014F21A, 030B21A and 036A21A) for COVID-19 vaccination.     The patient's past medical history included Sickness (felt sick for a week) from February 2020 to 2020. Previously administered products included for Product used for unknown indication: Flu vaccine in September 2021. Past adverse reactions to the above products included No adverse event with Flu vaccine. Concurrent medical conditions included Penicillin allergy.   On 07-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 04-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 26-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Nov-2021, the patient experienced HYPOAESTHESIA (numbness from his elbows down to his hands/numbness from his knees down to his feet) (seriousness criterion medically significant) and FATIGUE (felt fatigue/chronic fatigue) (seriousness criterion medically significant). On an unknown date, the patient experienced FEELING ABNORMAL (sleeps all night and when he wakes up he does not feel refreshed/feels like he was a walking zombie) (seriousness criterion medically significant). The patient was treated with BUPROPION at an unspecified dose and frequency; ESCITALOPRAM OXALATE (LEXAPRO) for Fatigue, at an unspecified dose and frequency and GABAPENTIN ongoing since an unknown date for Numbness, at an unspecified dose and frequency. At the time of the report, FEELING ABNORMAL (sleeps all night and when he wakes up he does not feel refreshed/feels like he was a walking zombie) outcome was unknown and HYPOAESTHESIA (numbness from his elbows down to his hands/numbness from his knees down to his feet) and FATIGUE (felt fatigue/chronic fatigue) was resolving.            Concomitant medications were not reported. Patient did not have any diagnosis of Covid-19 pre or post vaccination. but actually felt sick for a week in Feb2020 after a trip to a place where Covid-19 was pretty high but he did not get tested.  The patient had seen a number of health care providers like a neurologist and psychiatrist among them. MRI and blood works were fine. He was on corporate disability from 15Nov2021-15Feb2022. The numbness gets amplified when things were quiet, it comes to the forefront. The doctors were saying this might be chronic fatigue. He sleeps all night and when he wakes up he does not feel refreshed. He takes 2 naps a day and there were times, he feels like he was a walking zombie. The numbness and fatigue were better now but they were still there.   Company comment: This Spontaneous case concerns a 52-year-old, male patient, with no relevant medical history, who experienced the unexpected, serious (Medically significant) events of fatigue, hypoaesthesia and feeling abnormal, approximately 7 days after the administration of the third dose of mRNA-1273 vaccine. Patient felt fatigue and he had numbness from his elbows down to his hands and knees down to his feet, consulted a neurologist and psychiatrist, performed a non-specified magnetic resonance image and blood works that were reported as fine. He was on corporate disability for approximately 3 months. Doctors told him that it could be chronic fatigue.  He was prescribed by a psychiatrist with Bupropion but it gave him headache so he stopped it after 5 days. He was also prescribed with Lexapro for the fatigue by the physician assistant but that gave him headache and dry mouth so he also stopped it. He is currently taking Gabapentin for the numbness. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-551583 (Patient Link).; Sender's Comments: This Spontaneous case concerns a 52-year-old, male patient, with no relevant medical history, who experienced the unexpected, serious (Medically significant) events of fatigue, hypoaesthesia and feeling abnormal, approximately 7 days after the administration of the third dose of mRNA-1273 vaccine. Patient felt fatigue and he had numbness from his elbows down to his hands and knees down to his feet, consulted a neurologist and psychiatrist, performed a non-specified magnetic resonance image and blood works that were reported as fine. He was on corporate disability for approximately 3 months. Doctors told him that it could be chronic fatigue.  He was prescribed by a psychiatrist with Bupropion but it gave him headache so he stopped it after 5 days. He was also prescribed with Lexapro for the fatigue by the physician assistant but that gave him headache and dry mouth so he also stopped it. He is currently taking Gabapentin for the numbness. The benefit-risk relationship of mRNA-1273 is not affected by this report.