Information has been received from a health professional concerning a 4 year old male with asthma nos and no known drug allergies who was vaccinated with MMR II (lot 642695/0490M) in his left thigh. Concomitant suspect therapy included diphtheria toxoid/pertussis vaccine/teta and poliovirus vaccine inactivated. It was reported that five minutes after the child received the MMR II he had a severe allergic reaction with redness, swelling and pain at the injection site, hives all over his body and he experienced difficulty breathing. The child was treated with Benadryl IM and orally and dexamethasone IM. The child was taken to the hospital where he was admitted one night for observation. Redness, swelling, and pain at injection site, hives all over body and difficulty breathing were considered to be immediately life-threatening. Additional info has been requested. Additional info has been received from a health professional and a physician. The health professional reported that the child developed a swollen, red leg at the site of the vaccination. She reported that the child developed extreme total body itching and that the child was hospitalzied for one day and treated with steroids. The health professional reported that the child had recovered and was now "well." It was also reported that the child had no illness at the time of vaccination. The physician reported that a few minutes after the child had his vaccinations he developed a reaction in his left leg where the vaccination was given. He reported that this swelled up and got quite red. The child then developed a diffuse body rash with diffuse itching and his face became quite red and his lips swellled slightly. The physician reported that the child never developed respiratory distress and his lung fields were completely clear. The physician reported  that the child was watched in the office for about 45 mintues. He reported that the child was treated with "25mgs IM" with a good response and given 4mgs of dexamethasone IM shortly before he left the office. THe physician also reported that the child has a history of lots of reactions to foods and tends to itch anytime he gets exposed to a new food and that he certainly has had an itching reaction to eggs. He reported that the child was sent home with a Xopenex nebulizer with insturctions to use if he experienced any wheezing. The child was also given Prelone 15mgs per teaspoon and was to be taken 5ml twice daily for the next 5 days. The physician stated, "there is little doubt that he has had an allergy reaction to the tiny amount of egg protein in the MMR." The physician reported that he would refer the child to an allergist. on 8/19/02 at 5:30pm the child presented to the ER with sudden onset of extreme allergy rash. It was reported that the child had an extreme itching rash, total body was shaking and had eye drainage with no fever. It was reported that the child was agitated and itching and upon physical exam ENT was all OK except for rhinitis. A complete blood count was drawn. The ER diagnosed the child with an allergic reaction to MMR II. The child was admitted to the hospital overnight, did well and was eating. On 8/20/02 the child's events were considered resolved and he was discharged from the hospital. No additional info is expected.