3-4 hours after [first dose], heart immediately started contracting  and pulsating like someone was wrapping a bag and squeezing her heart really really hard/heart couldn't beat fully/ beating very very quickly,significant heart issues; shooting pain up in my chest into my throat down her body and it almost paralytic and really painful/ chest pain/pain in my chest every once in a while; a lot of heaviness in chest a lot of tension/like someone was sitting on chest/ At some point it felt like her chest was ripping open in between feeling super constrictive; shooting pain up in my chest into my throat down her body and it almost paralytic and really painful.; This spontaneous case was reported by a consumer and describes the occurrence of PALPITATIONS (3-4 hours after [first dose], heart immediately started contracting  and pulsating like someone was wrapping a bag and squeezing her heart really really hard/heart couldn't beat fully/ beating very very quickly,significant heart issues), CHEST PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful/ chest pain/pain in my chest every once in a while), CHEST DISCOMFORT (a lot of heaviness in chest a lot of tension/like someone was sitting on chest/ At some point it felt like her chest was ripping open in between feeling super constrictive) and PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful.) in a 27-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 030H21B) for COVID-19 vaccination.   The patient's past medical history included COVID-19 in April 2021. Concurrent medical conditions included Food allergy (corn allergy), Milk allergy (casein sensitivity), Pollen allergy, Food allergy (crab allergy), Milk allergy, Gluten sensitivity (possible gluten sensitivity), Allergy to antibiotic (a bunch of different antibiotics including amoxicillin.) and Drug allergy (vaccinations allergy).  On 01-Dec-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Dec-2021, the patient experienced PALPITATIONS (3-4 hours after [first dose], heart immediately started contracting  and pulsating like someone was wrapping a bag and squeezing her heart really really hard/heart couldn't beat fully/ beating very very quickly,significant heart issues) (seriousness criterion medically significant), CHEST PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful/ chest pain/pain in my chest every once in a while) (seriousness criterion medically significant), CHEST DISCOMFORT (a lot of heaviness in chest a lot of tension/like someone was sitting on chest/ At some point it felt like her chest was ripping open in between feeling super constrictive) (seriousness criterion medically significant) and PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful.) (seriousness criterion medically significant). At the time of the report, PALPITATIONS (3-4 hours after [first dose], heart immediately started contracting  and pulsating like someone was wrapping a bag and squeezing her heart really really hard/heart couldn't beat fully/ beating very very quickly,significant heart issues), CHEST PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful/ chest pain/pain in my chest every once in a while), CHEST DISCOMFORT (a lot of heaviness in chest a lot of tension/like someone was sitting on chest/ At some point it felt like her chest was ripping open in between feeling super constrictive) and PAIN (shooting pain up in my chest into my throat down her body and it almost paralytic and really painful.) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In April 2021, SARS-CoV-2 test: positive (Positive) Positive. On an unknown date, Electrocardiogram: normal (normal) Normal.  It was unknown what other vaccines were given within 1 month prior to Moderna COVID-19 vaccine. The patient always had problems with vaccinations, she would have more side effects than the average person with the flu shot. The patient had the Moderna vaccinations several months ago. She had serious side effects, was put in the hospital for a time. She was in and out of the emergency room a number of times, having heart palpitations and other things. She was able to make doctor appointments once she got insurance. They could not figure out what was wrong with her. The patient got really sick ever since she got the vaccination. Most of the problems were with her heart. They did not know what to do anymore. 3-4 hours after the first vaccine, her heart immediately started contracting and pulsating, like someone was wrapping a bag and squeezing her heart really hard. It was like her heart could not beat fully, but it was beating very quickly. Then it got to the point it would send a shooting pain up her chest into her throat and down her body and it was almost paralytic and really painful. She had a lot of heaviness in her chest, and a lot of tension. At some point it felt like her chest was ripping open in between feeling super constrictive. That lasted for about 24-48 hours with reoccurring symptoms that lasted. She went to the emergency room every week because she was having significant heart issues after that. Her EKGs came back normal. It was reported that heart problems were still ongoing.  Company Comment: This spontaneous case concerns a 27-year-old, female patient with no reported relevant medical history, who experienced the unexpected, serious (medically significant) events of Palpitations, Chest pain with Chest discomfort and Pain described as debilitating pain spreading from the chest down to the throat and rest of the body. The events started within 3-4 hours after receiving the first dose of mRNA-1273 which continued to persist for 12-48 hours and became intermittent thereafter. The events prompted multiple consults in the emergency department. The exact diagnosis and medical intervention administered were not provided in the case, although the EKGs were reported normal. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-577936 (Patient Link).; Sender's Comments: This spontaneous case concerns a 27-year-old, female patient with no reported relevant medical history, who experienced the unexpected, serious (medically significant) events of Palpitations, Chest pain with Chest discomfort and Pain described as debilitating pain spreading from the chest down to the throat and rest of the body. The events started within 3-4 hours after receiving the first dose of mRNA-1273 which continued to persist for 12-48 hours and became intermittent thereafter. The events prompted multiple consults in the emergency department. The exact diagnosis and medical intervention administered were not provided in the case, although the EKGs were reported normal. The benefit-risk relationship of mRNA-1273 is not affected by this report.