pain in her arm just like a stiffness; pain in her arm just like a stiffness; Arm arthritis at the 2 shots site; hair loss; fatigue; Diagnosed Autoimmune Diseases; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program. The reporter is the patient.  A 66-year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 15Feb2021 12:00 (Lot number: EN6201) at the age of 66 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "symptoms of autoimmune disease" (unspecified if ongoing), notes: some symptoms of autoimmune disease not aggressive in the  past; "Rhematoid arthiritis" (unspecified if ongoing); "hair loss for many years" (ongoing), notes: issues with hair loss for many years; "osteoarthritis" (unspecified if ongoing); "prediabetic" (unspecified if ongoing); "meniscal plaque" (unspecified if ongoing); "some minor arrhythmias" (unspecified if ongoing); "a little bit of fatigue" (unspecified if ongoing), notes: a little bit of fatigue in the past. Family history included: "Husband has Parkinson's disease" (unspecified if ongoing), notes: Husband has Parkinson's disease. No history of all previous immunization with the Pfizer vaccine considered as suspect. No additional Administered Vaccines. No prior Vaccinations (within 4 weeks). No events following prior vaccinations. There were no concomitant medications. The following information was reported: AUTOIMMUNE DISORDER (medically significant) with onset 2021, outcome "unknown", described as "Diagnosed Autoimmune Diseases"; PAIN IN EXTREMITY (non-serious), MUSCULOSKELETAL STIFFNESS (non-serious) all with onset 15Feb2021 16:00, outcome "recovering" and all described as "pain in her arm just like a stiffness"; ARTHRITIS (non-serious) with onset 2021, outcome "unknown", described as "Arm arthritis at the 2 shots site"; ALOPECIA (non-serious) with onset 2021, outcome "unknown", described as "hair loss"; FATIGUE (non-serious) with onset 2021, outcome "unknown", described as "fatigue". No event required a visit to Emergency Room, but event required a visit to Physician Office. The patient underwent the following laboratory tests and procedures: blood test: (unspecified date) negative, notes: Osteoarthiritis blood work; rheumatoid factor positive: (unspecified date) normal, notes: before vaccination; (25Apr2021) positive, notes: Blood work for R factor rheumatoid arthritis. Additional Context: Patient had the first dose of the vaccine on 15Feb2021 and second dose 08Mar2021 and she thinks she might have had in the past some symptoms of autoimmune disease but were not aggressive. The only thing patient can remember was a little bit of fatigue and issues with her hair falling in the past. She had side effects from the 2 vaccines: diagnosed Autoimmune Diseases, Arm arthritis at the 2 shots site, hair loss, fatigue! After those two vaccines her body started acting up on her. Pain in arm like stiffness started at 4pm the day she got the vaccine and the left arm muscle has not healed since. When she lifted her arm it was uncomfortable and it has been more than 2 months and still the area of muscle was still stiff whereas the right one was smooth and flexible. She was not sure how a little needle can hurt the muscle. After the first dose of the vaccine she had mostly pain in her arm just like a stiffness not numbness. She also felt tired. Tiredness started after the first dose of the vaccine. Hair was falling started changing like where it was disintegrating and getting brittle and dry: she has had ongoing hair loss for many years but this was different it was like her hair turned into hay and it is so dry it breaks and it is horrible. When she went to the rheumatologist she was told that this was sometimes a symptom of Sjogren's and Lupus but she was never diagnosed with those until she got her results on 25Apr2021 from the lab. Patient stated interestingly the opposite the blood work she got was normal for the R factor rheumatoid arthritis and the others had been normal for 15 years and the blood work to see if osteoarthritis was always negative but now it was positive.