Age: 1.01
Sex: F
Vaccine: IPV, MMR, VARCEL
Symptoms: Speech disorder
Clinical narrative: Initial report received from another manf on 12Oct05. It was initially reported by a consumer and subsequently by a physician that a 12 month old female pt received the third dose of IPOL, lot number R0235, the first dose of MMR, lot number 1510J, first dose of varicella vaccine lot number 1684J and the first dose of Tuberculin PPD (manf and lot number not reported) on 07Mar00. The pt has no history of known drug reaction/allergies or medical history. She was born with a good Apgar and weighed 6lbs 4 ounces. Previously vaccinations the pt has received are Hep B vaccine, dose one 16Mar99, lot number 629628/1779H, dose two on 26Apr99, lot number 629631/0195J and dose three on 08Dec99, lot number 632215/0967J. Acel-Immune dose one on 26Apr99, lot number 462-312, dose two on 23Jun99, lot number462-355 and dose three on 09Sep99, lot number 464-302. Hibtiter dose one  on 26Apr99, lot number 423203A, dose two on 23Jun99 lot number 450103A and dose three on 09Sep99 lot number 460103A. Ipol dose one on 26Apr99 lot number P0167 and dose two on 23Jun99 lot number N0956. Post vaccination with hep B vaccine, MMR and Varicella vaccine the pt developed mercury poisoning and was diagnosed with autism. She was not able to talk, she would only repeat back what was said to her. The pt could not chew and was on baby food until five years of age. It was reported that the pt was on chelation therapy and was improving somewhat. Unspecified medical attention was sought. There was no product quality complaint involved. The pt was noted to have developmental delay at her 12 month visit (exact date not reported) She was referred for further evaluation. On 29Mar00 the pt had a developmental evaluation that indicated the pt had a three month delay with abnormal tone, delayed postural position and protective responses, and decreased strength and stability. The pt was rated using the Bayley scales of infant development. She had a raw mental scale of 76, chronological age of 66, rating of significantly delayed, and a developmental age of 9 months. She had a raw motor scale of 56, a chronological age of 60, a rating of significantly delays, and a developmental age of 9 months. The pt's behavior rating scales included: orientation/engagement was within normal limits with a raw of 45 and in the 51st percentile, emotional regulation was within normal limits with a raw score of 34 and in the 57th percentile, motor quality was non optimal with a raw score of 26 and in the 8th percentile, and her total raw score was within normal limits with a raw score of 115 and in the 35th percentile. Suggestions for the pt included activities to help facilitate developmental skills, referral to regional center for occupational and physical therapy intervention, a visit with the physician in three months, reschedule for Baily S after physician visit and a possible MRI after the next visit. The pt also received the following immunizations Trihibit dose one on 21Jun00 lot number U01480C, Prevnar dose one on 26Sep00 lot number 471-225 and dose two on 24Jan01 lot number 472051. The physician has indication that she had not seen the pt in a year or more. She stated in response to the pt's adverse events that she wasn't sure that was the case. This report has previously been submitted by the other company on 18Aug05 and 15Sep05.