Age: 30.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: SARS-CoV-2 test, Small fibre neuropathy, Stress, Sweat gland disorder, Tachycardia
Clinical narrative: MAST CELL ACTIVATION SYNDROME; POSTURAL ORTHOSTATIC  TACHYCARDIC SYNDROME; LIVEDO RETICULARIS; EPSTEIN-BARR REACTIVATION; SLEEPING 12 HOURS A DAY; IN PAIN ALL THE TIME; FOOD INTOLERANCE; RIGHT EAR TINNITUS; SMALL FIBRE NEUROPATHY; SWEAT GLAND DISORDER; TACHYCARDIA; VEIN DISORDER; VISUAL SNOW SYNDROME; HYPOAESTHESIA; PARESTHESIA; CYTOKINE TEST; MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA DECREASED; FATIGUE; TRIGEMINAL NEURALGIA; NEUROPATHY PERIPHERAL; TUNNEL VISION; COSTOCHONDRITIS; ANXIETY; BALANCE DISORDER; BLOOD PRESSURE FLUCTUATION; BURNING SENSATION; DEREALISATION; DISTURBANCE IN ATTENTION; EAR DISCOMFORT; ERYTHEMA; FEELING ABNORMAL; HEAD DISCOMFORT; INTERLEUKIN LEVEL INCREASED; MEMORY IMPAIRMENT; MENTAL FATIGUE; MUSCLE TWITCHING; NEURALGIA; OCCIPITAL NEURALGIA; OCULAR DISCOMFORT; PHOTOPHOBIA; PRURITUS; STRESS; This spontaneous report received from a health care professional by a Regulatory Authority, VAERS (Vaccine Adverse Event Reporting System) (VAERS ID 2396709) via parent concerned a 30 year old male of an unspecified race and ethnicity. The patient's height and weight were not reported. The patient's concurrent conditions included: penicillin allergy (Amoxicillin). The patient had no allergies and had no any illness at the time of vaccination. The patient had no medical history before vaccination. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, intramuscular, batch number: 1808982 and expiry: Unknown) dose was not reported, 1 total administered to the right arm on 30-JUL-2021 for an unspecified indication. Age at time of vaccination 30 years old. Concomitant medications included omeprazole. On 30-JUL-2021, the patient experienced full head pressure at top temples crown (head discomfort), exasperated by exercise prolonged periods of talking stress, imbalance when walking (balance disorder) accompanied by head pressure floaty feeling (feeling abnormal), brain fog, short-term memory (memory impairment) impaired focus (disturbance in attention). The patient also had mental, physical post exertional fatigue (mental fatigue) (fatigue). The patient also had ocular discomfort, paraesthesia (numbness/tingling) and felt abnormal. It was mentioned that the right side head crown nerve pain (neuralgia) diagnosed by neurologist as occipital trigeminal neuralgia (right upper). The right ear popping (ear discomfort) and blood pressure swings (blood pressure fluctuation) (120/70 greater than 160/100). The patient also experienced left pectoral muscle twitching (muscle twitching), had costochondritis after exercise anxiety, veins in both hands protrusion (vein disorder) and had arm, neck, leg muscle twitching. The patient had extremity pins needles (paraesthesia), full body itching (pruritus), had tachycardiac episodes (tachycardia) and experiencing derealization episodes (derealisation). The patient also had tunnel vision, light sensitivities (photophobia), visual snow eye pressure (visual snow syndrome). It was also mentioned that the patient had right leg numbness (hypoaesthesia), hand redness in both hands on palm sides (erythema), had hand burning (burning sensation) and neuropathy on both sides (neuropathy peripheral). On 06-DEC-2021, the patient experienced skin with significantly reduced sweat gland nerve (sweat gland disorder) and on 02-JUN-2022, fiber density consistent with small fiber neuropathy.  On 30-JUL-2021, Laboratory data included: Cytokine test Radiance cytokine panel elevated, IL-6, IL-10, Interleukin level increased, and Macrophage inflammatory protein-1 alpha decreased, blood pressure swings 120/70 greater than 160/100, chemokine test (CCL4) low, long haul index (laboratory test) 2.5. On an unspecified date patient experienced, dysautonomia a including blood pooling in extremities legs and hands, postural orthostatic tachycardic syndrome that causes large variances in blood pressure 120/70 lying down while 160/110 when stand up, adrenal dumps, livedo reticularis, right ear tinnitus, epstein-barr reactivation, post exertional malaise, histamine intolerance including mast cell activation syndrome, brain fog including derealization, food intolerance, right eye blurriness, right ear popping, in pain all the time, sleeping 12 hours a day, Negative nucleocapsid test (never had covid), 40 plus tests, punch biopsy, autonomic testing results were not reported, Abnormal test results, received upsetting, negative test results but did not want to go over that today.  Consumer also stated that he was disable when first talked about adverse event, vaccine have ruined his life and he needs help, he had not been working for 16 months. Consumer has had to move in back with parents due to disability; physical and economical. The patient lived in tremendous pain daily. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from anxiety, balance disorder, blood pressure fluctuation, burning sensation, costochondritis, cytokine test, derealisation, disturbance in attention, ear discomfort, erythema, fatigue, feeling abnormal, head discomfort, hypoaesthesia, interleukin level increased, macrophage inflammatory protein-1 alpha decreased, memory impairment, mental fatigue, muscle twitching, neuralgia, neuropathy peripheral, occipital neuralgia, ocular discomfort, paresthesia, photophobia, pruritus, small fibre neuropathy, stress, sweat gland disorder, tachycardia, trigeminal neuralgia, tunnel vision, vein disorder, and visual snow syndrome, and the outcome of postural orthostatic tachycardic syndrome, livedo reticularis, epstein-barr reactivation, mast cell activation syndrome, sleeping 12 hours a day, in pain all the time, right ear tinnitus and food intolerance was not reported. This report was serious (Other Medically Important Condition, and Disability Or Permanent Damage). This case is a duplicate of 20221134051. This case, from the same reporter is linked to 20221134487.  Following receipt of additional information from reporter (Parent) on 14-NOV-2021. It was determined that nullification and deletion was required for Manufacturer Report Number 20221134051 as it was duplicate of Manufacturer Case Number 20220829480. All relevant information regarding Manufacturer Report Number 20221134051 will be submitted under Manufacturer Case Number 20220829480, The following information was updated and incorporated into the case narrative: Additional reporter added as Parent, Patient details updated in person tab, Patient's date of birth added, Patient History Including Pre-Existing Medical Conditions updated, Additional events added (postural orthostatic tachycardic syndrome, food intolerance, livedo reticularis, right ear tinnitus, epstein-barr reactivation, sleeping 12 hours a day, mast cell activation syndrome, In pain all the time). Laboratory data added.; Sender's Comments: V1: This follow up adds information about 20221134051 as duplicate of this case, reporter details, pre-Existing Medical Conditions updated, additional events, laboratory details. MAC updated .  20220829480-mast cell activation syndrome. Follow-up received regarding Clinical Details. The event has an unknown/unclear temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event. Therefore, the WHO Causality is considered indeterminate. The company causality is considered unassessable.   20220829480-covid-19 vaccine ad26.cov2.s- Neuropathy peripheral, Small fibre neuropathy, Trigeminal neuralgia,  Anxiety, Balance disorder, Blood pressure fluctuation, Burning sensation, Costochondritis, Cytokine test, Derealisation, Disturbance in attention, Ear discomfort, Erythema,  Feeling abnormal, Head discomfort, Hypoaesthesia, Interleukin level increased, Macrophage inflammatory protein-1 alpha decreased, Memory impairment, Mental fatigue, Muscle twitching, Neuralgia,  Occipital neuralgia, Ocular discomfort, Paraesthesia, Photophobia, Pruritus, Stress, Sweat gland disorder, Tachycardia, Tunnel vision, Vein disorder, Visual snow syndrome. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s). Therefore, this event(s) is considered unassessable.  20220829480-covid-19 vaccine ad26.cov2.s-Fatigue. This event(s) is labeled and is therefore considered potentially related.