Age: 53.0
Sex: M
Vaccine: VARZOS
Symptoms: Arthralgia, Chills, Dry skin, Feeling hot, Generalised oedema
Clinical narrative: feeling of warmth all over body; Shaking all over; joint pain; Fingers dry and cracked; Fingers dry; swelling of legs; swelling of knees; Body got bigger swelling all over; Fever; itching skin; chills, every 2-3 weeks; Couldn't sleep; This non-serious case was reported by a consumer via call center representative and described the occurrence of fever in a 53-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   On 28-SEP-2022, the patient received Shingrix (intramuscular). On 28-SEP-2022, less than a day after receiving Shingrix, the patient experienced fever (Verbatim: Fever), itchy skin (Verbatim: itching skin), chills (Verbatim: chills, every 2-3 weeks) and insomnia (Verbatim: Couldn't sleep). In OCT-2022, the patient experienced generalized swelling (Verbatim: Body got bigger swelling all over), swelling of legs (Verbatim: swelling of legs) and swelling of knees (Verbatim: swelling of knees). In DEC-2022, the patient experienced chapped skin (Verbatim: Fingers dry and cracked) and dry skin (Verbatim: Fingers dry). In FEB-2023, the patient experienced joint pain (Verbatim: joint pain). On an unknown date, the patient experienced tremor (Verbatim: Shaking all over) and feeling of warmth (Verbatim: feeling of warmth all over body). The patient was treated with steroids nos (Steroid Pack (Nos)) and steroids nos (Steroid Shot (Nos)). The outcome of the fever and insomnia were resolved and the outcome of the itchy skin, chills, tremor, joint pain, chapped skin and dry skin were not resolved and the outcome of the generalized swelling, swelling of legs and swelling of knees were resolving and the outcome of the feeling of warmth was unknown.   It was unknown if the reporter considered the fever, itchy skin, chills, insomnia, generalized swelling, tremor, joint pain, feeling of warmth, chapped skin, dry skin, swelling of legs and swelling of knees to be related to Shingrix.     It was unknown if the company considered the fever, itchy skin, chills, insomnia, generalized swelling, tremor, joint pain, feeling of warmth, chapped skin, dry skin, swelling of legs and swelling of knees to be related to Shingrix.   Additional Information: GSK Receipt Date: 11-APR-2023 The case was self reported by the patient. The patient was calling to ask about treatment for his multiple adverse events. The patient received a dose of Shingrix and the same evening of the vaccination, he began having fever, itching skin, chills and could not sleep. The patient reported that his body was getting bigger and bigger (swelling) all over, and now it was localized to his knees, bilaterally and it seems to be improving, but was still present. The patient still got chills every 2 to 3 weeks, with shaking all over. The patient fingers were very dry and stated that if he did not apply lotion every 2 hours then they would crack. The patient also experienced feeling of warmth all over body. The patient had experienced joint pain since February 2023. The patient was seeing a Rheumatologist, who told him these were adverse side effects to Shingrix.  The patient had a Steroid pack and a Steroid shot, neither of which were helpful. Provided Medical Information telephone number to give to his physicians. The reporter consented to follow up.