Age: 32.0
Sex: F
Vaccine: COVID19
Symptoms: Conversion disorder, Paralysis, Product dose omission issue, Pyrexia, Seizure
Clinical narrative: Paralyzed; had seizures; First patient started blacking out and loosing balance. Then patient could not walk  anymore and was diagnosed with functional neurological disorder. Patient could not walk anymore; fever which was really really high; did not receive second dose; This spontaneous case was reported by a consumer and describes the occurrence of PARALYSIS (Paralyzed), SEIZURE (had seizures) and CONVERSION DISORDER (First patient started blacking out and loosing balance. Then patient could not walk  anymore and was diagnosed with functional neurological disorder. Patient could not walk anymore) in a 32-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 041C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 26-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In 2021, the patient experienced PARALYSIS (Paralyzed) (seriousness criterion medically significant), SEIZURE (had seizures) (seriousness criterion medically significant), CONVERSION DISORDER (First patient started blacking out and loosing balance. Then patient could not walk  anymore and was diagnosed with functional neurological disorder. Patient could not walk anymore) (seriousness criterion medically significant), PYREXIA (fever which was really really high) and PRODUCT DOSE OMISSION ISSUE (did not receive second dose). The patient was treated with BUSPIRONE for Adverse event, at an unspecified dose and frequency and LORAZEPAM for Adverse event, at an unspecified dose and frequency. In 2021, PRODUCT DOSE OMISSION ISSUE (did not receive second dose) had resolved. At the time of the report, PARALYSIS (Paralyzed), SEIZURE (had seizures), CONVERSION DISORDER (First patient started blacking out and loosing balance. Then patient could not walk  anymore and was diagnosed with functional neurological disorder. Patient could not walk anymore) and PYREXIA (fever which was really really high) had not resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant drugs were not reported. The vaccine was administered on the nondominant left arm. Patient experienced symptoms in around a month following vaccination or might be less. The healthcare professionals (HCPs) could not find what was wrong with patient. Symptoms were getting worse and worse. Patient was given Buspirone and lorazepam. The hospital also gave patient another medicine but they did not mention to patient which. Curiously, symptoms got worse after giving patient this medication..  Company Comment: This case concerns a 32-year-old, female patient with no previous relevant medical history reported, who experienced the unexpected events of paralysis, seizure and conversion disorder. The events occurred on an unknown number of days after the first dose of mRNA-1273. The rechallenge was unknown since the events have not resolved. The benefit-risk relationship of mRNA-1273 is not affected by this report. Further information was requested.; Sender's Comments: This case concerns a 32-year-old, female patient with no previous relevant medical history reported, who experienced the unexpected events of paralysis, seizure and conversion disorder. The events occurred on an unknown number of days after the first dose of mRNA-1273. The rechallenge was unknown since the events have not resolved. The benefit-risk relationship of mRNA-1273 is not affected by this report. Further information was requested.