Age: 48.0
Sex: F
Vaccine: COVID19
Symptoms: Angina pectoris, Condition aggravated, Headache, Ophthalmic migraine, Oropharyngeal pain
Clinical narrative: Heart pain/worsened; headaches after my 2nd dose which would not respond to Tylenol or ibuprofen/non-stop headaches; my vision was weird zigzag moving lines that formed a circle like shape.; ocular migraine; Heart pain; sore throat; This spontaneous case was reported by a consumer and describes the occurrence of ANGINA PECTORIS (Heart pain) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 024C21A and 042B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Latex allergy, Allergy to antibiotic (sulfamethoxazole and trimethoprim), Nickel sensitivity, Irritable bowel syndrome, Arthritis and Migraine.   On 14-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 18-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 20-May-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced ANGINA PECTORIS (Heart pain) (seriousness criterion medically significant). 20-May-2021, the patient experienced OROPHARYNGEAL PAIN (sore throat). On 25-May-2021, the patient experienced OPHTHALMIC MIGRAINE (ocular migraine) and VISUAL IMPAIRMENT (my vision was weird zigzag moving lines that formed a circle like shape.). On an unknown date, the patient experienced CONDITION AGGRAVATED (Heart pain/worsened) and HEADACHE (headaches after my 2nd dose which would not respond to Tylenol or ibuprofen/non-stop headaches). The patient was treated with PARACETAMOL (TYLENOL) for Headache, at an unspecified dose and frequency and IBUPROFEN for Headache, at an unspecified dose and frequency. On 25-May-2021, OPHTHALMIC MIGRAINE (ocular migraine) had resolved. At the time of the report, ANGINA PECTORIS (Heart pain) had not resolved and CONDITION AGGRAVATED (Heart pain/worsened), OROPHARYNGEAL PAIN (sore throat), VISUAL IMPAIRMENT (my vision was weird zigzag moving lines that formed a circle like shape.) and HEADACHE (headaches after my 2nd dose which would not respond to Tylenol or ibuprofen/non-stop headaches) outcome was unknown.            Concomitant product use was not provided.  Patient reported she had a history of migraine but nothing like the events experienced.  She had consist headaches after her 2nd dose which would not respond to paracetamol or ibuprofen.  She emailed her physician but did not see in person.   Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   This case was linked to MOD-2021-208995 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 25-Jun-2021: Added allergies, medical history, vaccine information, and events; event outcomes updated.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.