Sex: M
Vaccine: VARZOS, VARZOS
Symptoms: Herpes zoster, Ophthalmic herpes zoster, Pain, Rash, Vaccination failure
Clinical narrative: Suspected vaccination failure; herpes virus was noted in the eye/ he had a spot on his left eye; developed shingles/states he also had it on his forehead, face; Pain/ "pain and all of thatand typical rash; spot on his left eye, and it was bothering him states he also had it on his forehead, face, and the eye was really involved; This serious case was reported by a other health professional via call center representative and described the occurrence of vaccination failure in a 92-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   On 29-MAR-2021, the patient received the 2nd dose of Shingrix. On 28-NOV-2020, the patient received the 1st dose of Shingrix. On an unknown date, an unknown time after receiving Shingrix and Shingrix, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant), herpes ophthalmic (Verbatim: herpes virus was noted in the eye/ he had a spot on his left eye) (serious criteria GSK medically significant), shingles (Verbatim: developed shingles/states he also had it on his forehead, face), pain (Verbatim: Pain/ "pain and all of thatand typical rash) and rash (Verbatim: spot on his left eye, and it was bothering him states he also had it on his forehead, face, and the eye was really involved). The outcome of the vaccination failure, herpes ophthalmic, shingles, pain and rash were resolved.   It was unknown if the reporter considered the vaccination failure, herpes ophthalmic, shingles, pain and rash to be related to Shingrix and Shingrix.     The company considered the vaccination failure and herpes ophthalmic to be unrelated to Shingrix and Shingrix. It was unknown if the company considered the shingles, pain and rash to be related to Shingrix and Shingrix.   Additional Information: GSK Receipt Date:17-OCT-2024 The physician assistant stated that a patient had both doses of Shingrix and developed shingles. She states that the patient came into the office on 17-SEP-2024 because he had a spot on his left eye, and it was bothering him. She states that he also had it on his forehead, face and the eye was really involved. She knew it was shingles, he had the typical symptoms pain and all of that and typical rash. The patient's optometrist saw him and herpes virus was noted in the eye as well.  Health care professional states the patient was treated for shingles and it has resolved, states it responded nicely. This case was considered as suspected vaccination failure since the details regarding laboratory confirmation of shingles were unknown at the time of reporting.; Sender's Comments: Vaccination failure is a listed event which, due to the following criteria (insufficient information provided about time to onset and laboratory confirmation of disease) is considered unrelated to GSK vaccine Shingrix(dose 1 and 2) .                     Herpes ophthalmic is an unlisted event which is considered unrelated to GSK vaccine Shingrix(dose 1 and 2).