Sex: F
Vaccine: COVID19
Symptoms: Acute lymphocytic leukaemia, Biopsy bone marrow, Blood calcium, Laboratory test, Platelet count decreased
Clinical narrative: diagnosed with Acute Lymphoblastic Leukemia (ALL) in bone marrow; her platelets were almost at 0; UTI; This is a spontaneous report from a contactable consumer. A 66-year-old female patient (reporter's Mother in law) received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration on 26Apr2021 (Batch/Lot number was not reported) as DOSE 2, SINGLE for covid-19 immunisation. Medical history included parathyroid polyps, 5th cycle of chemotherapy, elevated calcium levels. The patient's concomitant medications were not reported. Her mother in law's first dose was in the middle Mar2021, maybe 15Mar2021, she was not sure. Caller reported her mother-in-law received the Pfizer covid vaccine (first dose in Mar2021, second dose 26Apr2021) and then a month after second shot, became diagnosed with Acute Lymphoblastic Leukemia (ALL) in bone marrow. Caller know the vaccine doesn't change genetic makeup, but reporter read about T-cells and that's what gets stimulated with the vaccine but there are T-cells in cancer. The reporter thought patient was having an autoimmune response, her platelets were almost at 0 at the hospital, she had a UTI at the same time and that was why we took her to the hospital. The reporter was thankful it happened that way because it got her to go to the hospital. She received platelets while she was there but she wasn't taking to them and they started to suspect something else so a few days after bone marrow biopsy, we found out she ALL. She also had parathyroid polyps in the past about a year ago. 2 weeks prior to the vaccine, she had perfect lab work you know at a normal follow up so we do have a baseline there. Caller stated the patient was in remission, they caught very early, but caller know it will be time for boosters to be discussed at some point. It's strange with the time line but patient had the second dose of the vaccine on 26Apr2021, a couple weeks prior to this she had perfect labs, the reason they were even monitoring her labs was because it was for her parathyroid in which there was a concern in which it had elevated calcium levels due to a polyps they found. A month after second shot, she all the sudden was diagnosed with ALL, leukemia in the bone marrow. Caller asked if there was something in the vaccine that could bring it to her attention or any reports of effecting the immune system or symptoms with white blood cells. If there was anything with the vaccine that lingers in the body, there was anything reported like that. Her mother in law at the moment was doing well, she was on a 5th cycle of chemotherapy, they want her to do 8 in total, but she had perfect bone marrow and lumbar test due to all the intensive treatment for ALL. The patient underwent lab tests and procedures which included biopsy bone marrow: abnormal, blood calcium: elevated calcium levels, laboratory test: perfect labs, platelet count decreased: abnormal (almost at 0). The outcome of events was unknown.   Information on the lot/batch number has been requested.