Age: 76.0
Sex: M
Vaccine: VARZOS
Symptoms: Blister, Body temperature increased, Herpes zoster, Pain, Post herpetic neuralgia
Clinical narrative: Information has been received from a physician assistant concerning a male with hypertension, osteoarthritis and no drug allergies whose wife in December 2008 was vaccinated SQ with a 0.65 ml dose of ZOSTAVAX (Merck).  Concomitant therapy included PRILOSEC, DIOVAN, TIMOPTIC, vitamin D (unspecified), omega-3 vitamin and vitamin B complex.  On 02-FEB-2009 the male patient developed shingles.  He was seen in the office with blisters and post herpetic neuralgia pain on the right groin, right thigh and low back on the right side.  The area affected was dermatome L1.  The female who received the vaccine was not experiencing any symptoms or problems.  Follow-up information was received from the physician assistant concerning the 76 year old male with a history of chickenpox during childhood whose 74 year old wife on 29-DEC-2008 was vaccinated with a 0.5 ml dose of ZOSTAVAX (Merck) (lot #:  663198/1419X) into the right deltoid.  It was reported that the patient and his wife lived together.  On 09-Feb-2009, the male patient developed shingles.  He developed vesicular rash with extensive lesions on the right hip, groin and low back.  The area affected was dermatome L2.  The patient had grade 9 pain.  The maximum temperature was 99.  At the time of this report, the patient was recovered.  The patient was enrolled in a program to identify if VZV is present and if it is present to identify if it is associated with the wild-type (WT) VZV strain or with the OKA/Merck vaccine VZV strain.  Additional information has been requested. This is in follow-up to report (s) previously submitted on 3/27/2009.  Information has been received from a physician assistant concerning a male with hypertension, osteoarthritis and no drug allergies whose wife in December 2008 was vaccinated SQ with a 0.65 ml dose of ZOSTAVAX (Merck).  Concomitant therapy included PRILOSEC, DIOVAN, TIMOPTIC, vitamin D (unspecified), omega 3 vitamin) and vitamin B complex.  On 02-FEB-2009 the male patient developed shingles.  He was seen in the office with blisters and post herpetic neuralgia pain on the right groin, right thigh and low back on the right side.  The area affected was dermatome L1.  The female who received the vaccine was not experiencing any symptoms or problems.  Follow-up information was received from the physician assistant concerning the 76 year old male with a history of chickenpox during childhood whose 74 year old wife on 29-DEC-2008 was vaccinated with a 0.5 ml dose of ZOSTAVAX (Merck) (lot #: 663198/1419X) into the right deltoid.  It was reported that the patient and his wife lived together.  On 09-FEB-2009, the male patient developed shingles.  He developed vesicular rash with extensive lesions on the right hip, groin and low back.  The area affected was dermatome L2.  The patient had grade 9 pain.  The maximum temperature was 99.  At the time of this report, the patient was recovered.  Follow up information reported that the physician assistant was unable to provide further adverse event information.  No further information is available.