Age: 68.0
Sex: M
Vaccine: VARZOS
Symptoms: Pain, Pain in extremity, Pruritus, Pyrexia, Vaccine positive rechallenge
Clinical narrative: This case was reported by a consumer via call center representative and described the occurrence of influenza-like symptoms in a 68-year-old male patient who received SHINGRIX for prophylaxis. The patient's past medical history included chickenpox. Previously administered products included SHINGRIX with an associated reaction of influenza like illness (also experienced fever, chills, body aches, pain at injection site and headache (refer the case for 1st dose_US2018GSK128833)). On 18th June 2018, the patient received the 2nd dose of SHINGRIX (intramuscular) .5 ml. In June 2018, 5 days after receiving SHINGRIX, the patient experienced ear pain, neck pain, shoulder blade pain, itchy scalp and pain in fingers. On 18th June 2018, the patient experienced influenza-like symptoms, injected limb mobility decreased, fever, chills, general body pain and headache. On 5th July 2018, the patient experienced shingles. On an unknown date, the patient experienced burning sensation. The patient was treated with VALTREX and gabapentin. Rechallenge with SHINGRIX was positive. On an unknown date, the outcome of the influenza-like symptoms, injected limb mobility decreased, fever, chills, headache, ear pain, neck pain and shoulder blade pain were recovered/resolved and the outcome of the general body pain and pain in fingers were recovering/resolving and the outcome of the itchy scalp and burning sensation were not recovered/not resolved and the outcome of the shingles was unknown. It was unknown if the reporter considered the influenza-like symptoms, injected limb mobility decreased, fever, chills, general body pain, headache, ear pain, neck pain, shoulder blade pain, itchy scalp, pain in fingers, shingles and burning sensation to be related to SHINGRIX. Additional details were provided as follows: In the morning, at 10:15 am, the patient received 2nd dose of SHINGRIX on left deltoid. By 7:00 pm, that evening, the patient experienced more intense flu like symptoms, could barely move his left arm, experienced fever, chills, body aches and headache. He also complained of aching in his fingers. These symptoms were lasted 48 hours and had 5 days of feeling normal without any issues. After 5 days of vaccination, the caller reported that the patient started pain behind his right ear, radiating down the right side of his neck, his right clavicle and pinging out to his right shoulder blade. This lasted for 3 to 4 days. The patient reported every day following these initial symptoms occurring and the symptoms worsened. On 5th July 2018, the patient went to his physician for evaluation and was to physician diagnosed he had shingles. The caller reported that he never had shingles before receiving the vaccine and began treatment of VALTREX and gabapentin for the next 3 days and the pain became more frequent and intense. By Monday morning, the patient developed burning along the right side of his face, right eye, right side of lip and scalp itchiness. The patient saw his physician on Monday morning for re-evaluation and was started on a course or oral prednisone and continues the oral Gabapentin. This is 1 of 2 cases reported by the same reporter for the same patient.