Age: 65.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test
Clinical narrative: After 4 doses of Moderna vaccine got COVID; This spontaneous case was reported by a patient and describes the occurrence of COVID-19 (After 4 doses of Moderna vaccine got COVID) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     No Medical History information was reported.   On an unknown date, the patient received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form, second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form and first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced COVID-19 (After 4 doses of Moderna vaccine got COVID). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment, at an unspecified dose and frequency. At the time of the report, COVID-19 (After 4 doses of Moderna vaccine got COVID) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, SARS-CoV-2 test: (Positive) Positive, (Negative) negative, rapid test. 3 days in a row, (Negative) negative, rapid test. 3 days in a row, (Negative) negative, rapid test. 3 days in a row and (Positive) tested positive via rapid test..         Concomitant medication list was not provided. It was reported that the patient started Paxlovid immediately after positive test and took for 5 days. The patient tested negative 3 days in a row after completion of Paxlovid via rapid test. 5 days after the patient had completed Paxlovid the patient had sneezing, runny nose and tested positive via rapid test. The patient wanted to know if the Paxlovid dose should be 10 days. Event awareness date was given as 26-Jul-2022.  Company Comment: This spontaneous case concerns a 65-year-old female patient, with no reported medical history, who experienced unexpected, non-serious adverse event of special interest Covid19, after receiving 4 doses of mRNA-1273.  Onset latency could not be determined due to limited information on the dates of vaccination and the date of event onset.  Immediately after testing positive for Covid19, she took Nirmatrelvir/Ritonavir (Paxlovid) for 5 days with negative rapid test after completion.  However, around 5 days later she had sneezing, runny nose and tested positive again on rapid test.  The ongoing Covid19 pandemic could be a contributory factor.  The benefit risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a 65-year-old female patient, with no reported medical history, who experienced unexpected, non-serious adverse event of special interest Covid19, after receiving 4 doses of mRNA-1273.  Onset latency could not be determined due to limited information on the dates of vaccination and the date of event onset.  Immediately after testing positive for Covid19, she took Nirmatrelvir/Ritonavir (Paxlovid) for 5 days with negative rapid test after completion.  However, around 5 days later she had sneezing, runny nose and tested positive again on rapid test.  The ongoing Covid19 pandemic could be a contributory factor.  The benefit risk relationship of mRNA-1273 is not affected by this report.