chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 75.0
Sex: F
Vaccine: PPV
Symptoms: Erythema, Feeling hot, Pain, Rash erythematous, Urticaria
Clinical narrative: Arm pain with warm, red, sl raised c/w large hive at visit covers 10x20cm area.
Age: 1.0
Sex: F
Vaccine: IPV, MMR, VARCEL
Symptoms: Cough, Pyrexia, Viral infection
Clinical narrative: Chickenpox on head and all over body, low grade fever; coughing.
Age: 42.0
Sex: F
Vaccine: TD
Symptoms: Cellulitis, Injection site reaction
Clinical narrative: Cellulitis at injection site. Pt developed cellulitis at illegible injection site of TD (Diphtheria + Tetanus Toxoid Adult). Treatment: Erythromycin 500 mg PO Q 8 hours for 7 days (allergic to penicillin, cephalosporins, and carbapenem). No further information available.
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Erythema, Feeling hot
Clinical narrative: redness, warm to touch, area right arm
Sex: U
Vaccine: HBHEPB, VARCEL
Symptoms: Feeling hot, Injection site mass, Swelling, Tenderness
Clinical narrative: Swelling, lump, warm and tender to touch, legs, upper thigh, site of injection left thigh.
Age: 1.33
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC, VARCEL
Symptoms: Injection site erythema, Injection site oedema
Clinical narrative: Redness and swelling at all injection sites right and left leg.
Age: 4.0
Sex: F
Vaccine: IPV, MMR
Symptoms: Erythema, Feeling hot, Swelling, Tenderness
Clinical narrative: Shots given, Friday July16, right thigh red, swollen and tender to touch and warm. Shots on the yr, was no reaction.
Age: 3.0
Sex: M
Vaccine: DTAP, VARCEL
Symptoms: Dermatitis bullous, Pruritus
Clinical narrative: Presented to clinic with rash (Bullous lesions) on trunk, legs, CBC done, started on antihistamines on 07/16/04-rash resolved on 7/20-Father phoned today 7/22 stated rash appearing and very itchy. CBC normal limits.
Age: 21.0
Sex: M
Vaccine: TTOX, TYP
Symptoms: Dermatitis bullous
Clinical narrative: Clear water like bumps on both left and right of my arms. Wiped them off and they popped.
Age: 49.0
Sex: M
Vaccine: HEPA
Symptoms: Erythema, Fatigue, Feeling hot, Flushing, Myalgia
Clinical narrative: On Thursday 07/22/04 pt's face was really flushed and red. He felt hot. On Friday 7/23/04 he felt his body hurting and ver tired after a high fever of 101-102. Every 4 hours he was given Tylenol. He mostly slept most of both dates.
Age: 49.0
Sex: M
Vaccine: HEPA
Symptoms: Pyrexia, Somnolence
Clinical narrative: On Thursday 07/22/04 pt's face was really flushed and red. He felt hot. On Friday 7/23/04 he felt his body hurting and ver tired after a high fever of 101-102. Every 4 hours he was given Tylenol. He mostly slept most of both dates.
Age: 1.0
Sex: M
Vaccine: HIBV, MMR, PNC
Symptoms: Erythema, Injection site induration
Clinical narrative: Within 5 minutes of MMR given, patient developed localized reaction 50x50mm redness and 25x25mm of induration.
Age: 0.54
Sex: M
Vaccine: DTAP, HIBV, PNC
Symptoms: Feeling hot, Injection site swelling
Clinical narrative: Swollen injection site 1-2 cm bump, warm to touch. Local reaction to Prevnar . Use warm compress.
Age: 0.3
Sex: M
Vaccine: DTAP, HIBV, IPV, PNC
Symptoms: Erythema, Skin nodule
Clinical narrative: Localized reaction observed 7/26/04 with 3x4cm well-demarcated nodule with central area of erythema on right thigh. No warmth or tenderness to palpation. No sign skin break down or neurosis. No systemic sxs: afebrile. Advised to monitor for adverse change.
Age: 38.0
Sex: F
Vaccine: TD
Symptoms: Lymphadenopathy, Pain, Paraesthesia
Clinical narrative: Client awoke @ 4am with right arm pain and right hand tingling and swollen nodes under her arm. She saw Dr on Monday 7/26/2004, her Dr told her to take Benadryl 50mg one today and one today and one tomorrow and Ibuprofen 600mg and Ibuprofen 600mg and she should tell better by 7/27/2004.
Age: 4.0
Sex: F
Vaccine: DTAP, HEPA, IPV, MMR
Symptoms: Erythema, Oedema, Pruritus
Clinical narrative: Mom called on 6/9/04. Child had taken a nap 6/8 soon after getting immunizations and woke up with left upper arm very swollen and red and itchy. No other sx. Mom has been treating child with Motrin and cold compresses, advised topical Benadryl for relief of itchiness. Advised mom to contact MD if Sx do not get better within 1 week. 07/22/04 T.C. to mom. Sx lasted only 1 week. Child ok now.
Age: 49.0
Sex: F
Vaccine: HEP
Symptoms: Hypoaesthesia, Muscle spasms, Muscular weakness, Pain, Paraesthesia
Clinical narrative: 5d after vaccination arm pain, muscle weakness generalized, numbness/tingling hands and feet, leg cramps up at noc. Bowel and bladder UA Blood lab drawn, Medrol dose pak.
Age: 33.0
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Erythema, Flushing, Injection site rash
Clinical narrative: Localized reaction both arms left arm varicella, right arm MMR. Both given SQ, localized red rash. Ice to left arm. Clarinex 5mg given PO also states feeling flushed.
Age: 1.5
Sex: F
Vaccine: HBHEPB, IPV, VARCEL
Symptoms: Drug ineffective, Viral infection
Clinical narrative: Attenuated chickenpox- 1st lesions appeared 7/28/2004
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Urticaria
Clinical narrative: Pt came in with hives all over face, arms, legs, torso at 1:35. Mother voiced child had received Immunizations at  12PM and broke out shortly afterwards.
Age: 6.0
Sex: F
Vaccine: DTAP, MMR
Symptoms: Erythema, Injection site mass, Oedema, Pain
Clinical narrative: Red and swollen 4 1/4" x 3 1/2" (redness) c/o pain, hard area to right thigh (received Dtap)
Age: 4.0
Sex: U
Vaccine: DTAP, IPV, MMR
Symptoms: Erythema, Oedema
Clinical narrative: Day 1 swelling and redness to elbow given Benadryl (no fever, no pain) Day 2 swelling and redness to wrist Day 6 swelling  receded Tx was Benadryl (right arm)
Age: 18.0
Sex: F
Vaccine: HEP, HEPA, TYP, YF
Symptoms: Myalgia, Nausea, Pyrexia
Clinical narrative: Fever 101, myalgias, neck supple, nausea lasted on and off 24+ hours treated with Tylenol.
Age: 33.0
Sex: M
Vaccine: HEP, VARCEL
Symptoms: Acne, Hyperhidrosis, Nail discolouration, Skin discolouration
Clinical narrative: Discoloration of fingernails, profuse sweating, outbreaks of pimples over entire body, black spots over entire body.
Age: 5.0
Sex: M
Vaccine: DTAP, HEPA, IPV, MMR
Symptoms: Erythema
Clinical narrative: 12x13cm area of Erythema, no fever, no vomiting, no fluctuance, no pain, right upper arm
Sex: F
Vaccine: HEPA, UNK
Symptoms: Asthenia, Hypoaesthesia
Clinical narrative: The pt has a history of multiple sclerosis and is taking Beta interferon. She was vaccinated with hepatitis A vaccine and given immune globulin for possible hepatitis A exposure in a child care center, three days later she developed left hand, leg and lower back numbness and left leg weakness.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Feeling hot, Rash erythematous, Tenderness, Urticaria
Clinical narrative: 7/30/04 hives developed 40-48 hrs after vaccine given. 4-5cm area raised and red on left arm and shoulder +tender +warm. Orapred 30mg=2 tsp given 4:45PM. Benadryl 1 1/2 tsp given (20mg)
Age: 20.0
Sex: M
Vaccine: ANTH, YF
Symptoms: Periorbital oedema, Urticaria
Clinical narrative: Pt had moderate to severe periorbital swelling and truncal urticarial rash approximately 3-4 hours after receiving yellow fever (1st shot) and Anthrax #3 both left arm
Age: 32.0
Sex: M
Vaccine: LYME
Symptoms: Arthralgia, Back pain, Hyperaesthesia, Laboratory test abnormal, Muscle spasms
Clinical narrative: Following the second Lymerix shot, I developed severe burning, hypersensitivity, muscular cramping, and joint pain in low-mid back, buttocks, pelvis/perineum, hips, legs, and feet.  These systems have persisted for 4 years at moderate to severe intensity.  This has impacted every aspect of my and my family's lives.  I have seen numerous specialists who have ruled out (through MRI, discogram, nerve conduction, and other tests) a primary neurologic cause.  I have received numerous blood tests.  The ELISA/western blot test for Lyme prior to the vaccine was negative.  However, recent DNA tests for Lyme were positive.  The Lyme specialist I am presently seeing, believes I may have had dormant Lyme prior to vaccination (based on similar problems I had from 1990-1992, which inexplicably went away)and that is was reactivated by the vaccine.
Age: 32.0
Sex: M
Vaccine: LYME
Symptoms: Skin burning sensation
Clinical narrative: Following the second Lymerix shot, I developed severe burning, hypersensitivity, muscular cramping, and joint pain in low-mid back, buttocks, pelvis/perineum, hips, legs, and feet.  These systems have persisted for 4 years at moderate to severe intensity.  This has impacted every aspect of my and my family's lives.  I have seen numerous specialists who have ruled out (through MRI, discogram, nerve conduction, and other tests) a primary neurologic cause.  I have received numerous blood tests.  The ELISA/western blot test for Lyme prior to the vaccine was negative.  However, recent DNA tests for Lyme were positive.  The Lyme specialist I am presently seeing, believes I may have had dormant Lyme prior to vaccination (based on similar problems I had from 1990-1992, which inexplicably went away)and that is was reactivated by the vaccine.
Age: 45.0
Sex: F
Vaccine: HEP
Symptoms: Chest pain, Pain
Clinical narrative: Pt. received initial hep vac on 5/26/04 without any adverse effects. Afterwards,contracted 5th Disease and had to postpone 2nd vaccination until 7/14/04. Felt able to take the 2nd vaccination then. Given in R arm. One to two hours later felt pain going down R arm, then up arm, then into R chest. Was sent by supervisor to ER and was seen. ER does not know what caused the event but have requested that our institution titer pt now and see if 3rd shot can be avoided.
Age: 29.0
Sex: F
Vaccine: SMALL
Symptoms: Blister, Erythema, Herpes zoster, Rash, Skin ulcer
Clinical narrative: Intial lesions appeared to be blisters, then progressed to a more dissiminated rash, urgent care doctor diagnosed as erythema, later diagnosed as shingles.
Age: 49.0
Sex: F
Vaccine: TD
Symptoms: Asthenia, Myalgia, Neck pain, Shoulder pain
Clinical narrative: Patient experienced muscle pain and general weakness in left arm along with neck and shoulder pain. Pain started June 1, 2004. Gradually progressed to where patient had difficulty driving and typing with left arm. Patient was prescribed Vioxx 25 mg. and Skelaxin 800 mg. on June 24, 2004.  Since there was no reduction in pain, patient started physical therapy on July 2, 2004. She responded positively to physical therapy and was discharged from therapy on July 30, 2004. She was advised to continue the PT exercises.
Age: 1.58
Sex: M
Vaccine: DTAP, IPV
Symptoms: Convulsion, Laboratory test abnormal, Pyrexia
Clinical narrative: Fever, clonic tonic seizure. Vaccine administered in the morning; symptoms occurred that evening.  Nurse follow up on 08/30/04 states: "Complete."
Age: 75.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Rash
Clinical narrative: Information has been received from a health professional concerning a 75 year old female who on 10/11/02 was vaccinated IM in the right deltoid with a dose of pneumococcal 23 polyvalent. Secondary suspect vaccinations on that same day included an IM dose in the left deltoid of influenza virus vaccine. On 10/12/02, the patient noticed a small rash on her abdomen. On 10/13/03, the sunburn-like rash extended from the back of the patient's neck to her buttocks and from both of her shoulders down to her wrists. The patient was subsequently hospitalized for three days. While hospitalized, the patient was treated with unspecified antibiotics and diphenhydramine HCl. Subsequently, the patient's ash resolved. The health professional also considered the rash to be an other important medical event (OMIC) No further information is available.
Age: 73.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Cellulitis, Injection site erythema, Injection site warmth, Pyrexia
Clinical narrative: Information has been received from a physician concerning a 73 year old female patient with no past medical history who on 10/20/02 at 2:21 PM was vaccinated with a second dose of pneumococcal vaccine 23 polyvalent (lot # 641027/1051L) (IM), in the right deltoid. Concomitant therapy that day included a second dose of influenza virus vaccine (FLUVIRIN) (IM) (lot # P35502KA), in the left deltoid. The patient at that time had also received two monthly injections of cyanobalamin (B12 injections) (previous injection was reported to be in September 2002). There was no illness at the time of vaccination. It was reported that it had been greater than five years since the first pneumococcal vaccine 23 polyvalent vaccine for the patient. On 10/20/02 the patient was feverish and her right arm was red. The patient reportedly had localized cellulitis/local redness and warmth at the right upper deltoid. The patient was treated with warm soaks, diphenhydramine HCl, cetirizine, meloxicam, and six days of cefditoren pivoxil. It was reported that the area cleared on 10/25/02. It was noted that the patient had no adverse symptoms following prior vaccinations. The physician reported that the patient recovered from the cellulitis. Additional information has been requested.
Age: 71.0
Sex: F
Vaccine: PPV
Symptoms: Erythema, Oedema, Pain, Petechiae
Clinical narrative: Information has been received from a RN concerning a 71 year old white female with allergies to aspirin (ASA), penicillin, meperidine HC1 (Demerol) and intravenous pyelogram dye who on 03Oct2002, at 09:00, was vaccinated IM in the right deltoid with the first dose of pneumococcal 23v polysaccharide vaccine (lot # 644104/0873M). There was no illness at the time of vaccination. The RN reported that on 03Oct03, at 20:10, the pt developed edema, pain, redness and petechiae (22cmx15cmx2cm). Medical attention was not sought. On 04Oct2003, the pt recovered from the edema, pain, redness and petechiae (22cmx15cmx2cm). Additional information has been requested.
Age: 65.0
Sex: F
Vaccine: PPV
Symptoms: Cellulitis, Injection site erythema, Injection site pain
Clinical narrative: Information has been received from a pharmacist concerning a 65 year old female with no known allergies and a known thyroid condition who on 10/10/03 was vaccinated with a second dose of pneumococcal 23v polysaccharide vaccine (lot # 647634/0863N). Concomitant medication included levothyroxine sodium. On 10/11/03 the patient's arm was red and sore and she developed cellulitis. The symptoms started in the right deltoid. On 10/12/03, the patient was treated as an outpatient with IV cefazolin sodium in an acute care clinic. A few days later on 10/14/03, the patient was hospitalized for three days. She was treated with IV clindamycin. The patient was discharged on oral cephalexin. As of 10/24/03, the patient was improving but was not completely recovered. It was reported that this was the patient's second dose after a five year interval. On 11/7/03, it was reported that the patient has since recovered. There was no product quality complaint involved. The pharmacist also reported additional patients who had similar experiences following exposure to pneumococcal 23v polysaccharide vaccine. Additional information has been requested.
Age: 42.0
Sex: F
Vaccine: FLUX, PPV
Symptoms: Injection site oedema, Pruritus
Clinical narrative: Information has been received from a LPN concerning a 42 year old female with a recent diagnosis of multiple sclerosis and a penicillin allergy and a past medical history of kidney stone (1985) who on approximately 28Oct03 was vaccinated with a second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy that day included influenza virus vaccine (unspecified) and interferon beta1a (Avonex). Subsequently the pt developed at the inj site on right deltoid, localized swelling of upper arm 10 cm x 15cm and mild itching. The pt was afebrile. The pt was treated with diphenhydramine HC1 (Benadryl) and cool compress. It was also reported that another pt had similar symptoms. Additional information has been requested.
Age: 57.0
Sex: F
Vaccine: FLUX, PPV
Symptoms: Asthenia, Dysphagia, Headache, Hypertension, Lymphadenopathy
Clinical narrative: Information from a physician assistant concerning a 57 year old white female with a concurrent condition of disabled who on 24Oct03 at 12:30PM was vaccinated IM in the left deltoid with a second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy on the same day included influenza virus vaccine (unspecified). An illness at the time of vaccination was a UTI. On 25Oct03 at approximately 22:00, (previously reported as over the weekend), the pt developed a fever of 101.7, muscle aches, elevated blood pressure, difficulty swallowing, pounding headache, generalized weakness, lymphadenopathy, vertigo and nausea. It was noted that the pt did not go to the ER and on 27Oct03, she presented to the physicians office. Diagnostic laboratory tests were a CBC and a BMP, results not reported. The treatment of choice was ibuprofen (Advil). The pt recovered on 29Oct03. Unspecified medical attention was sought. There was no product quality complaint involved. No further information is requested.
Age: 57.0
Sex: F
Vaccine: FLUX, PPV
Symptoms: Myalgia, Nausea, Pyrexia, Vertigo
Clinical narrative: Information from a physician assistant concerning a 57 year old white female with a concurrent condition of disabled who on 24Oct03 at 12:30PM was vaccinated IM in the left deltoid with a second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy on the same day included influenza virus vaccine (unspecified). An illness at the time of vaccination was a UTI. On 25Oct03 at approximately 22:00, (previously reported as over the weekend), the pt developed a fever of 101.7, muscle aches, elevated blood pressure, difficulty swallowing, pounding headache, generalized weakness, lymphadenopathy, vertigo and nausea. It was noted that the pt did not go to the ER and on 27Oct03, she presented to the physicians office. Diagnostic laboratory tests were a CBC and a BMP, results not reported. The treatment of choice was ibuprofen (Advil). The pt recovered on 29Oct03. Unspecified medical attention was sought. There was no product quality complaint involved. No further information is requested.
Age: 55.0
Sex: F
Vaccine: PPV
Symptoms: Erythema, Pain, Rash macular, Swelling, Urticaria
Clinical narrative: Information has been received from a licensed practical nurse concerning a 55 year old white female with a hx of migraines and no known drug allergies who on the afternoon of 28OCT2003 was vaccinated IM in the left deltoid with a first dose of dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy included Midrin, Zomig, and Toprol. There was no illness at the time of vaccination. It was noted that "two weeks prior" the patient had received a dose of influenza virus vaccine. Subsequently, the patient developed "blotchy welts of the entire upper arm" described as swelling, erythema, and marked soreness over the left upper arm with 3 separate 2 cm patches over the lateral surface of marked soreness over the left upper arm 3 separate 2 cm patches over the lateral surface of the arm and "pain of the entire arm to the neck." Medical attention was treated with Benadryl. There was no product quality complaint involved. It was also reported that another patient had similar symptoms. Additional information has been requested.
Age: 52.0
Sex: F
Vaccine: PPV
Symptoms: Dry skin, Feeling hot, Flushing
Clinical narrative: Information has been received from a RN and a 52 year old white female RN with an insect venom allergy and a history of pneumonia who on 04Nov03, at 11:30 was vaccinated IM in the left deltoid with the first dose of pneumococcal 23v polysaccharide vaccine. There was no concomitant therapy or illness at the time of vaccination. It was reported by the RN and the pt that, immediately after vaccination, at about 11:32, the pt experienced a hot, dry, flushing sensation from her neck to her head and to her ears and also experienced a tickle in her throat. Unspecified medical attention was sought, but no treatment or laboratory/diagnostic tests were required. The tickle in the pt's throat resolved after a few minutes and all of her other symptoms gradually subsided over 1 1/2 hours. On that same day, the pt was considered to be recovered. Additional information is not expected.
Age: 53.0
Sex: F
Vaccine: PPV, PPV
Symptoms: Bacterial infection, Disorientation, Drug ineffective, Hearing impaired, Herpes simplex
Clinical narrative: Information has been received from a physician concerning a 54 year old female with recurrent sinusitis, allergies to amoxicillin (+) clavulanate potassium, sulfamethoxazole (+) trimethoprim, cephalexin, ciprofloxacin hydrochloride, levofloxacin, clarithromycin, loracarbef, doxycycline, and famciclovir that cause documented hives and swelling, food allergies including pine nuts and sulfites and a history of a hysterectomy and BSO (1999) who on 10/18/94 and 2/20/04 was vaccinated with a first and second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy included cetirizine hydrochloride, 10mg once a day, atorvastatin calcium, 10mg once a day, and fluticasone propionate nasal spray frequently. The patient also carries an epinephrine injector. It was reported that the patient sees an allergist and, despite being followed by an ENT specialist, has recurrent sinusitis. On 4/14/04 the patient was hospitalized with disorientation. It was noted that she had received an injection of cefoxitin in the emergency room. She was diagnosed with pneumococcal bacteremia, and pneumococcal meningitis with obstructive hydrocephalus. The patient was admitted to the intensive care unit and treated with IV penicillin, vancomycin, and methylprednisolone sodium succinate. The patient developed an allergic reaction requiring readmission to the ICU and desensitization to penicillin starting with very low dosage and then gradually increasing. She had developed significant hearing loss especially in the left ear which occurred about he time of a severe outbreak of herpes simplex on the left side of her face. She had involvement of cranial nerves VI, VII, VIII, AND XII. On 5/22/04 she required readmission to the hospital when she again appeared disoriented but her cultures were negative. She responded to hydration, antihistamines, glucocorticoids, and famciclovir. A skin biopsy documented herpes simplex and eliminated varicella zoster. It was reported that although this patient did survive she had a well documented and severe illness despite receiving the pneumococcal vaccination 10 years before her illness and then again two months before her illness. The physician noted that he was not aware of the patient having cellular or humoral immunodeficiency. She had had HIV testing which was negative and had had normal globulin levels. It was reported that the reference lab for the hospital using AML found that her Pneumococcal organism was serotype group 19. It was also noted that the physician reported that he generally vaccinated with pneumococcal 23v polysaccharide vaccine at a younger age for those patients at risk because he feels it would be less likely one would see drug resistant pneumococcal infections in the community.Additional information has been requested.  Follow up on 09/09/04 states: "Follow up information received on 08/24/04 contained the following adverse experience: blister in the right dorsum of the right hand (05/04/04).  Additional information has been requested."
Age: 53.0
Sex: F
Vaccine: PPV, PPV
Symptoms: Hydrocephalus, Hypersensitivity, Meningitis
Clinical narrative: Information has been received from a physician concerning a 54 year old female with recurrent sinusitis, allergies to amoxicillin (+) clavulanate potassium, sulfamethoxazole (+) trimethoprim, cephalexin, ciprofloxacin hydrochloride, levofloxacin, clarithromycin, loracarbef, doxycycline, and famciclovir that cause documented hives and swelling, food allergies including pine nuts and sulfites and a history of a hysterectomy and BSO (1999) who on 10/18/94 and 2/20/04 was vaccinated with a first and second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy included cetirizine hydrochloride, 10mg once a day, atorvastatin calcium, 10mg once a day, and fluticasone propionate nasal spray frequently. The patient also carries an epinephrine injector. It was reported that the patient sees an allergist and, despite being followed by an ENT specialist, has recurrent sinusitis. On 4/14/04 the patient was hospitalized with disorientation. It was noted that she had received an injection of cefoxitin in the emergency room. She was diagnosed with pneumococcal bacteremia, and pneumococcal meningitis with obstructive hydrocephalus. The patient was admitted to the intensive care unit and treated with IV penicillin, vancomycin, and methylprednisolone sodium succinate. The patient developed an allergic reaction requiring readmission to the ICU and desensitization to penicillin starting with very low dosage and then gradually increasing. She had developed significant hearing loss especially in the left ear which occurred about he time of a severe outbreak of herpes simplex on the left side of her face. She had involvement of cranial nerves VI, VII, VIII, AND XII. On 5/22/04 she required readmission to the hospital when she again appeared disoriented but her cultures were negative. She responded to hydration, antihistamines, glucocorticoids, and famciclovir. A skin biopsy documented herpes simplex and eliminated varicella zoster. It was reported that although this patient did survive she had a well documented and severe illness despite receiving the pneumococcal vaccination 10 years before her illness and then again two months before her illness. The physician noted that he was not aware of the patient having cellular or humoral immunodeficiency. She had had HIV testing which was negative and had had normal globulin levels. It was reported that the reference lab for the hospital using AML found that her Pneumococcal organism was serotype group 19. It was also noted that the physician reported that he generally vaccinated with pneumococcal 23v polysaccharide vaccine at a younger age for those patients at risk because he feels it would be less likely one would see drug resistant pneumococcal infections in the community.Additional information has been requested.  Follow up on 09/09/04 states: "Follow up information received on 08/24/04 contained the following adverse experience: blister in the right dorsum of the right hand (05/04/04).  Additional information has been requested."
Age: 53.0
Sex: F
Vaccine: PPV, PPV
Symptoms: Bacterial infection, Blister, Disorientation, Drug ineffective, Herpes simplex
Clinical narrative: Information has been received from a physician concerning a 54 year old female with recurrent sinusitis, allergies to amoxicillin (+) clavulanate potassium, sulfamethoxazole (+) trimethoprim, cephalexin, ciprofloxacin hydrochloride, levofloxacin, clarithromycin, loracarbef, doxycycline, and famciclovir that cause documented hives and swelling, food allergies including pine nuts and sulfites and a history of a hysterectomy and BSO (1999) who on 10/18/94 and 2/20/04 was vaccinated with a first and second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy included cetirizine hydrochloride, 10mg once a day, atorvastatin calcium, 10mg once a day, and fluticasone propionate nasal spray frequently. The patient also carries an epinephrine injector. It was reported that the patient sees an allergist and, despite being followed by an ENT specialist, has recurrent sinusitis. On 4/14/04 the patient was hospitalized with disorientation. It was noted that she had received an injection of cefoxitin in the emergency room. She was diagnosed with pneumococcal bacteremia, and pneumococcal meningitis with obstructive hydrocephalus. The patient was admitted to the intensive care unit and treated with IV penicillin, vancomycin, and methylprednisolone sodium succinate. The patient developed an allergic reaction requiring readmission to the ICU and desensitization to penicillin starting with very low dosage and then gradually increasing. She had developed significant hearing loss especially in the left ear which occurred about he time of a severe outbreak of herpes simplex on the left side of her face. She had involvement of cranial nerves VI, VII, VIII, AND XII. On 5/22/04 she required readmission to the hospital when she again appeared disoriented but her cultures were negative. She responded to hydration, antihistamines, glucocorticoids, and famciclovir. A skin biopsy documented herpes simplex and eliminated varicella zoster. It was reported that although this patient did survive she had a well documented and severe illness despite receiving the pneumococcal vaccination 10 years before her illness and then again two months before her illness. The physician noted that he was not aware of the patient having cellular or humoral immunodeficiency. She had had HIV testing which was negative and had had normal globulin levels. It was reported that the reference lab for the hospital using AML found that her Pneumococcal organism was serotype group 19. It was also noted that the physician reported that he generally vaccinated with pneumococcal 23v polysaccharide vaccine at a younger age for those patients at risk because he feels it would be less likely one would see drug resistant pneumococcal infections in the community.Additional information has been requested.  Follow up on 09/09/04 states: "Follow up information received on 08/24/04 contained the following adverse experience: blister in the right dorsum of the right hand (05/04/04).  Additional information has been requested."
Age: 53.0
Sex: F
Vaccine: PPV, PPV
Symptoms: Hydrocephalus, Hypersensitivity, Hypoacusis, Laboratory test abnormal, Meningitis
Clinical narrative: Information has been received from a physician concerning a 54 year old female with recurrent sinusitis, allergies to amoxicillin (+) clavulanate potassium, sulfamethoxazole (+) trimethoprim, cephalexin, ciprofloxacin hydrochloride, levofloxacin, clarithromycin, loracarbef, doxycycline, and famciclovir that cause documented hives and swelling, food allergies including pine nuts and sulfites and a history of a hysterectomy and BSO (1999) who on 10/18/94 and 2/20/04 was vaccinated with a first and second dose of pneumococcal 23v polysaccharide vaccine. Concomitant therapy included cetirizine hydrochloride, 10mg once a day, atorvastatin calcium, 10mg once a day, and fluticasone propionate nasal spray frequently. The patient also carries an epinephrine injector. It was reported that the patient sees an allergist and, despite being followed by an ENT specialist, has recurrent sinusitis. On 4/14/04 the patient was hospitalized with disorientation. It was noted that she had received an injection of cefoxitin in the emergency room. She was diagnosed with pneumococcal bacteremia, and pneumococcal meningitis with obstructive hydrocephalus. The patient was admitted to the intensive care unit and treated with IV penicillin, vancomycin, and methylprednisolone sodium succinate. The patient developed an allergic reaction requiring readmission to the ICU and desensitization to penicillin starting with very low dosage and then gradually increasing. She had developed significant hearing loss especially in the left ear which occurred about he time of a severe outbreak of herpes simplex on the left side of her face. She had involvement of cranial nerves VI, VII, VIII, AND XII. On 5/22/04 she required readmission to the hospital when she again appeared disoriented but her cultures were negative. She responded to hydration, antihistamines, glucocorticoids, and famciclovir. A skin biopsy documented herpes simplex and eliminated varicella zoster. It was reported that although this patient did survive she had a well documented and severe illness despite receiving the pneumococcal vaccination 10 years before her illness and then again two months before her illness. The physician noted that he was not aware of the patient having cellular or humoral immunodeficiency. She had had HIV testing which was negative and had had normal globulin levels. It was reported that the reference lab for the hospital using AML found that her Pneumococcal organism was serotype group 19. It was also noted that the physician reported that he generally vaccinated with pneumococcal 23v polysaccharide vaccine at a younger age for those patients at risk because he feels it would be less likely one would see drug resistant pneumococcal infections in the community.Additional information has been requested.  Follow up on 09/09/04 states: "Follow up information received on 08/24/04 contained the following adverse experience: blister in the right dorsum of the right hand (05/04/04).  Additional information has been requested."
Age: 18.0
Sex: F
Vaccine: VARCEL
Symptoms: Abortion, Laboratory test abnormal, Medication error
Clinical narrative: Information has been received from a physician concerning an 18 year old female who was seen in the physician's office for a physical examination for college. While completing the physical examination forms, the physician saw that the patient had a history of never having the chicken pox and had never been vaccinated with varicella virus vaccine live. The patient was then vaccinated with a 0.5ml dose of varicella virus vaccine live (lot number unknown). The physician did not do a pregnancy test prior to the vaccination. Within 7-14 days of vaccination, the patient became pregnant. Unspecified medical attention was sought. There was no product quality complaint. Follow up information indicated that approximately 4-5 weeks after vaccination, the patient presented back to the physician's office due to a missed menses, and the physician conducted a pregnancy test which was positive. The patient decided to terminate the pregnancy due to social reasons. No further information is expected.
Age: 25.0
Sex: F
Vaccine: PPV
Symptoms: Cellulitis, Dizziness, Hypovolaemia, Injection site erythema, Injection site pain
Clinical narrative: Status post splenectomy after MVA at age 12. Received 2 doses of Pneumovax; last one about 5 years ago. Received vaccine left deltoid on 7/19/04. Complained of felling dizzy and redness/soreness at site. Seen 7/21/04 with 2cm erythema then 7/22/04 with 6cm erythema and increased WBC 29.5. Blood cultures times 2 negative. Given Rocephin IV.  Nurse follow up on 08/05/04 states: "(L) shoulder cellulitis; Septicemia; fever; decreased volume; leukocytosis."
Age: 25.0
Sex: F
Vaccine: PPV
Symptoms: Leukocytosis, Pyrexia, Sepsis, White blood cell count increased
Clinical narrative: Status post splenectomy after MVA at age 12. Received 2 doses of Pneumovax; last one about 5 years ago. Received vaccine left deltoid on 7/19/04. Complained of felling dizzy and redness/soreness at site. Seen 7/21/04 with 2cm erythema then 7/22/04 with 6cm erythema and increased WBC 29.5. Blood cultures times 2 negative. Given Rocephin IV.  Nurse follow up on 08/05/04 states: "(L) shoulder cellulitis; Septicemia; fever; decreased volume; leukocytosis."
Age: 31.0
Sex: M
Vaccine: ANTH, SMALL
Symptoms: Influenza like illness, Injection site erythema, Oedema
Clinical narrative: Approximately 10 days after vaccine right arm (bicep) area around injection was red. Experienced flu like symptoms the following day red area was even larger approx 5 inches radiating more towards the collar bone. Seen in the ICC for possible smallpox vaccinations reaction. Treated with Keflex and sent home. Two days later (25Jul04) followed up with ICC and followed up with Surgeon today. The redness had decreased some but is still noticeable where the swelling and redness was and where it was going.