Sex: F
Vaccine: RAB
Symptoms: Anxiety, Decreased appetite, Head discomfort, Headache
Clinical narrative: Worried; With first RabAvert dose had pressure headache in the head and stuff; With second RabAvert dose had pressure headache in the head and stuff; Have not had much of an appetite since the first dose of RabAvert; With first RabAvert dose had pressure headache in the head and stuff; With second RabAvert dose had pressure headache in the head and stuff; Case reference number US-BN-2023-001273 is a spontaneous case report initially received from a physician (reference number: USBAV23-0969) on 18-Jul-2023 and concerns a 54-year-old female patient.  The patient and no relevant medical history.  The patient's concomitant medication details were not provided.  On an unspecified date, the patient had an exposure (to be confirmed).  On 10-Jul-2023, unspecified amount of time after the exposure, the patient was vaccinated with the first dose of RabAvert (batch number: unknown), administered intramuscularly in an arm at an unknown dosage for post-exposure.  On 10-Jul-2023 also reported as the day after the first RabAvert dose (to be clarified), the patient had a pressure headache in the head and stuff (verbatim as reported) and had no appetite. As reported, the patient went to lie down.  On an unspecified date, the patient recovered from the event pressure headache in the head.  On 13-Jul-2023, unspecified amount of time after the exposure, the patient was vaccinated with the second dose of RabAvert (batch number: unknown), administered intramuscularly in an arm at an unknown dosage.  On an unspecified date, reported as the day after the first dose, the patient had a pressure headache in the head and stuff (verbatim as reported) and had no appetite. As reported, the patient went to lie down.  On an unspecified date, the patient recovered from the event pressure headache in the head.  On 17-Jul-2023, unspecified amount of time after the exposure, the patient was vaccinated with the third dose of RabAvert (batch number: unknown), administered intramuscularly in an arm at an unknown dosage at an emergency room (ER). As reported, the third RabAvert dose was done by the trainee at the ER, and the patient did not think the supervisor was watching the trainee well and the patient was worried if the trainee made a mistake, then the patient did not get full dose. As also reported, a nurse was acting like that was a hard vaccine to give (verbatim as reported).  On an unspecified date, reported as today, after the third RabAvert dose the day prior, the patient did not have a headache, but the patient did not have much of an appetite either. As reported, the patient really has not had much of an appetite since the first dose of RabAvert.  At the time of the initial report, event 'decreased appetite' was ongoing and outcome of the events 'worried', 'adverse event NOS' (after first RabAvert dose) and 'adverse event NOS' (after second RabAvert dose) was unknown.  The reporter did not provide seriousness or causality assessment for all reported events.  Additional information received on 19-Jul-2023 included local case ID.; Reporter's Comments: A 54-year-old female patient developed non-serious events of pressure headache in the head and stuff (verbatim as reported) and had no appetite on the day 1 after the patient was vaccinated with the first dose of RabAvert for post-exposure. Also, on the day 1 after the second dose of RabAvert, the patient developed non-serious events of pressure headache in the head and stuff (verbatim as reported) and had no appetite. Reportedly, the patient was vaccinated with the third dose of RabAvert, and it was done by the trainee at the ER, and the patient did not think the supervisor was watching the trainee well and the patient was worried if the trainee made a mistake. Anxiety and tension headache are unlisted for RabAvert according to the insert. Decreased appetite is listed per summary and unlisted per insert. Adverse event is considered as listed per company convention. The patient and no relevant medical history, and concomitant medication details were not provided. The event of decreased appetite was ongoing, and outcome of the events of worried, adverse event and adverse event was unknown. Considering implied temporal relationship and since the contributory role of the suspect vaccine cannot be excluded with certainty, the events have been considered as related to RabAvert. This case is considered as non-serious.; Sender's Comments: A 54-year-old female patient developed non-serious events of pressure headache in the head and stuff (verbatim as reported) and had no appetite on the day 1 after the patient was vaccinated with the first dose of RabAvert for post-exposure. Also, on the day 1 after the second dose of RabAvert, the patient developed non-serious events of pressure headache in the head and stuff (verbatim as reported) and had no appetite. Reportedly, the patient was vaccinated with the third dose of RabAvert, and it was done by the trainee at the ER, and the patient did not think the supervisor was watching the trainee well and the patient was worried if the trainee made a mistake. Anxiety and tension headache are unlisted for RabAvert according to the insert. Decreased appetite is listed per summary and unlisted per insert. Adverse event is considered as listed per company convention. The patient and no relevant medical history, and concomitant medication details were not provided. The event of decreased appetite was ongoing, and outcome of the events of worried, adverse event and adverse event was unknown. Considering implied temporal relationship and since the contributory role of the suspect vaccine cannot be excluded with certainty, the events have been considered as related to RabAvert. This case is considered as non-serious.