Age: 34.0
Sex: F
Vaccine: COVID19
Symptoms: Stiff tongue, Tongue pruritus, Urticaria
Clinical narrative: whole body burns and then the hives appear; Numb fingers; still has the rash; Hives in the shape of straight lines /  hives spread to her buttocks and arms / Big spot on forehead/Still have hives; Trouble breathing; Burning sensation under skin; Haven't been able to sleep; Haven't been able to work; Swollen eye; Itchy tongue; Itchy ears; stiff tongue; foot was swollen/Swollen right foot; This spontaneous case was reported by a consumer and describes the occurrence of URTICARIA (Hives in the shape of straight lines /  hives spread to her buttocks and arms / Big spot on forehead/Still have hives), DYSPNOEA (Trouble breathing), SKIN BURNING SENSATION (Burning sensation under skin), INSOMNIA (Haven't been able to sleep) and IMPAIRED WORK ABILITY (Haven't been able to work) in a 34-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 032S21A, 036A21A and 030M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Immunocompromised and HIV infection. Concomitant products included LORATADINE for Allergy NOS, OMEPRAZOLE for Gastritis, ABACAVIR SULFATE, DOLUTEGRAVIR SODIUM, LAMIVUDINE (TRIUMEQ) for HIV disease, CETIRIZINE for Itching, MINERALS NOS, VITAMINS NOS (CENTRUM A TO ZINC) and FISH OIL for an unknown indication.   On 08-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 08-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 07-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 18-Dec-2021, the patient experienced URTICARIA (Hives in the shape of straight lines /  hives spread to her buttocks and arms / Big spot on forehead/Still have hives), DYSPNOEA (Trouble breathing), SKIN BURNING SENSATION (Burning sensation under skin), INSOMNIA (Haven't been able to sleep), IMPAIRED WORK ABILITY (Haven't been able to work), EYE SWELLING (Swollen eye), TONGUE PRURITUS (Itchy tongue), EAR PRURITUS (Itchy ears), STIFF TONGUE (stiff tongue), PERIPHERAL SWELLING (foot was swollen/Swollen right foot), HYPOAESTHESIA (Numb fingers) and RASH (still has the rash). On an unknown date, the patient experienced BURNING SENSATION (whole body burns and then the hives appear). The patient was treated with PREDNISONE for No adverse reaction, at a dose of 1 dosage form; DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for No adverse reaction, at a dose of 1 dosage form and CETIRIZINE for No adverse reaction, at a dose of 1 dosage form. At the time of the report, URTICARIA (Hives in the shape of straight lines /  hives spread to her buttocks and arms / Big spot on forehead/Still have hives) had not resolved and DYSPNOEA (Trouble breathing), SKIN BURNING SENSATION (Burning sensation under skin), INSOMNIA (Haven't been able to sleep), IMPAIRED WORK ABILITY (Haven't been able to work), EYE SWELLING (Swollen eye), TONGUE PRURITUS (Itchy tongue), EAR PRURITUS (Itchy ears), STIFF TONGUE (stiff tongue), PERIPHERAL SWELLING (foot was swollen/Swollen right foot), BURNING SENSATION (whole body burns and then the hives appear), HYPOAESTHESIA (Numb fingers) and RASH (still has the rash) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Patient was received booster dose but she don't knowfor sure if she received a 100 mcg 3rd primary dose or a 50 mcg booster dose. Patient was stated that the hives were looks like as if someone had beaten me with a whip. Patient was stated  that she only feels relief when she is outdoors in the cold air and that indoors she feels as if she was on the stove   This case was linked to MOD-2022-438834, MOD-2022-446991 (Patient Link).