Age: 67.0
Sex: F
Vaccine: COVID19
Symptoms: Biopsy, Diffuse large B-cell lymphoma stage II
Clinical narrative: enlargement lymph node on the left side of my neck/ sever swelling to the left side of my neck/ left tonsil was extremely enlarged/ stage 2 diffuse large B-cell lymphoma; The initial case was missing the following minimum criteria: ICH-Unspecified AE. Upon receipt of follow-up information on 27Jun2023, this case now contains all required information to be considered valid.  This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 68-year-old female patient received BNT162b2 (BNT162B2), on 29Mar2022 as dose 4 (booster), single (Lot number: FJ6369) at the age of 67 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "obesity" (unspecified if ongoing); "never smoked" (unspecified if ongoing); "have not drunk alcohol since 1975", stop date: 1975; "never used illegal recreational drugs" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Lot number: EL1284), administration date: 23Dec2020, when the patient was 66-year-old, for COVID-19 immunization, reaction(s): "enlarged lymph node on the left side of my neck"; BNT162b2 (DOSE 2, SINGLE, Lot number: EK9231), administration date: 13Jan2021, when the patient was 66-year-old, for COVID-19 immunization, reaction(s): "enlarged lymph node on the left side of my neck"; BNT162b2 (DOSE 3 (BOOSTER), SINGLE, Lot number: 30145BA), administration date: 24Sep2021, when the patient was 67-year-old, for COVID-19 immunization, reaction(s): "enlarged lymph node on the left side of my neck". The following information was reported: DIFFUSE LARGE B-CELL LYMPHOMA STAGE II (hospitalization), outcome "not recovered", described as "enlargement lymph node on the left side of my neck/ sever swelling to the left side of my neck/ left tonsil was extremely enlarged/ stage 2 diffuse large B-cell lymphoma". The patient was hospitalized for diffuse large b-cell lymphoma stage ii (start date: Feb2023). The event "enlargement lymph node on the left side of my neck/ sever swelling to the left side of my neck/ left tonsil was extremely enlarged/ stage 2 diffuse large b-cell lymphoma" required physician office visit. The patient underwent the following laboratory tests and procedures: Biopsy: stage 2 diffuse large B-cell lymphoma. Therapeutic measures were taken as a result of diffuse large b-cell lymphoma stage II and included tonsillectomy and lymphadenectomy.  Clinical course: Other than obesity, the patient has been healthy. She has never smoked, has not drunk alcohol since 1975. She never used illegal recreational drugs. She would like to report a physical condition that may have resulted from the COVID vaccine. It started with an enlargement lymph node on the left side of her neck. Date Started: Dec2020 - Jan2021. She reported it to the CDC on 24Feb2021. It would reduce in size but never go away completely, enlarging each time she got another vaccine for COVID. She was hospitalized in Feb2023 with sever swelling to the left side of my neck. A tonsillectomy and lymphadenectomy & biopsies revealed stage 2 diffuse large B-cell lymphoma. Prior to biopsies were inconclusive - the ENT specialist wanted to definitive answer, plus the left tonsil was extremely enlarged. The surgery (Left lymphadenectomy and tonsillectomy) was not planned prior to taking the product.; Sender's Comments: Linked Report(s) : US-PFIZER INC-PV202300101142 Same patient and similar event, different vaccine doses.;