Age: 50.0
Sex: M
Vaccine: COVID19
Symptoms: Blood cholesterol, Blood cholesterol increased, Dizziness, Ear discomfort, Fall
Clinical narrative: Forgetfulness; Cholesterol high/CHOLESTEROL WAS BORDERLINE HIGH; Fall/fallen twice due to legs felt tingly; vertigo; Cold; Ear discomfort/felt like high altitude sickness in ear; Fall/fallen twice due to legs felt tingly; Dizziness/dizziness after sitting when stands caused falls; Paresthesia lower limb/fallen twice due to legs felt tingly; Tiredness; Headaches; Sluggishness; This spontaneous case was reported by a consumer and describes the occurrence of SLUGGISHNESS (Sluggishness), MEMORY IMPAIRMENT (Forgetfulness), BLOOD CHOLESTEROL INCREASED (Cholesterol high/CHOLESTEROL WAS BORDERLINE HIGH), the first episode of FALL (Fall/fallen twice due to legs felt tingly) and VERTIGO (vertigo) in a 50-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect products included non-company products UPADACITINIB (RINVOQ) for Rheumatoid arthritis and HYDROXYCHLOROQUINE for an unknown indication.    Concurrent medical conditions included Renal disease (for the past 15 years.) since 2006.   On 01-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Jun-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient started UPADACITINIB (RINVOQ) (Oral) at an unspecified dose On an unknown date, UPADACITINIB (RINVOQ) (Oral) dosage was changed to at an unspecified dose and UPADACITINIB (RINVOQ) (Oral) dosage was changed to at an unspecified dose. and HYDROXYCHLOROQUINE (unknown route) at an unspecified dose. In March 2021, the patient experienced SLUGGISHNESS (Sluggishness), FATIGUE (Tiredness) and HEADACHE (Headaches). On an unknown date, the patient experienced MEMORY IMPAIRMENT (Forgetfulness), BLOOD CHOLESTEROL INCREASED (Cholesterol high/CHOLESTEROL WAS BORDERLINE HIGH), the first episode of FALL (Fall/fallen twice due to legs felt tingly), VERTIGO (vertigo), NASOPHARYNGITIS (Cold), EAR DISCOMFORT (Ear discomfort/felt like high altitude sickness in ear), the second episode of FALL (Fall/fallen twice due to legs felt tingly), DIZZINESS (Dizziness/dizziness after sitting when stands caused falls) and PARAESTHESIA (Paresthesia lower limb/fallen twice due to legs felt tingly). At the time of the report, SLUGGISHNESS (Sluggishness), BLOOD CHOLESTEROL INCREASED (Cholesterol high/CHOLESTEROL WAS BORDERLINE HIGH), the last episode of FALL (Fall/fallen twice due to legs felt tingly), DIZZINESS (Dizziness/dizziness after sitting when stands caused falls), FATIGUE (Tiredness) and HEADACHE (Headaches) had not resolved, MEMORY IMPAIRMENT (Forgetfulness) outcome was unknown, VERTIGO (vertigo), NASOPHARYNGITIS (Cold) and EAR DISCOMFORT (Ear discomfort/felt like high altitude sickness in ear) was resolving and PARAESTHESIA (Paresthesia lower limb/fallen twice due to legs felt tingly) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood cholesterol: BORDERLINE HIGH.         Concomitant product use was not provided by the reporter. The patient had a rare form of kidney disease (although could not recall what it's called) for the past 15 years. He felt tired, sluggish for about a month and wondered if it was due to taking the covid vaccinations. He started getting headaches after the first covid vaccination. Patient also said he was forgetful about taking his RINVOQ. He took cholesterol medication as his cholesterol was borderline high. He was fallen twice due his legs felt tingly. He took Hydroxychloroquine but when it gave him vertigo (dizziness), he was only taking the medication at night. He thought it was the RINVOQ making him dizzy because when he stopped taking RINVOQ for two weeks because of having a cold, the dizziness stopped. Patient also said it felt as if he had high altitude sickness in his right ear. When he sits for a while he felt dizzy when he stands it caused him to fall several times. He took Hydrochloraquine (Patient assumes it's to help with his RA) and that his physician said this medication could cause the symptoms of vertigo, meaning it could possibly be the cause of the dizziness.  It was unknown if patient was enrolled in a COVID-19 Vaccine Trial. Treatment information was not provided.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in   Most recent FOLLOW-UP information incorporated above includes: On 08-Oct-2021: Significant live follow up appended events added and narrative updated