Age: 63.0
Sex: F
Vaccine: COVID19
Symptoms: Increased need for sleep, Investigation, Magnetic resonance imaging, Sleep apnoea syndrome
Clinical narrative: Her heart rate would go up and down from 160 to 140; Bronchospasms; Sleep apnea; She could do things for 15 minutes and then would have to take a nap; Brain fog started with COVID and became worse after she got the COVID vaccines; Brain fog started with COVID and became worse after she got the COVID vaccines; This is a spontaneous report received from contactable reporter (Nurse). The reporter is the patient.  A 65-year-old female patient received bnt162b2 (BNT162B2), on 20Jan2021 as dose 1, single (Lot number: EL3248) at the age of 63 years, in arm for COVID-19 immunisation. The patient's relevant medical history included: "High blood pressure" (ongoing), notes: diagnosed a long time ago; "Low thyroid" (ongoing), notes: diagnosed about ten years ago; "Asthma" (unspecified if ongoing), notes: in her 20s; "COVID-19", start date: 03Nov2020 (unspecified if ongoing); "Brain fog" (ongoing). The patient took concomitant medications. The following information was reported:  The patient had the vaccine early on since she is a nurse. She had not got over the COVID infection she had (clarified to have occurred prior to COVID vaccines) since at that time they were not saying not to take the vaccine while sick, CDC was recommending now to not be sick with COVID before getting a COVID-19 vaccine. She has been sick for almost three years post-COVID. At the time of COVID infection, she had a high fever, she was bedridden and could not even get up to go to the bathroom, she did go to the bathroom but it was hard to get up, she has seen so many doctors. The patient reported that she really has bad brain fog. It started with COVID and became worse after she got the COVID vaccines and reports she became bedridden after the vaccines. When asked to clarify which dose she became bedridden after, states it got worse with each dose of the COVID vaccine. She was followed up by pulmonary, cardiology, sleep apnea since she would quit breathing, she cannot even think and she was put on hormones from gynecology hoping that it would help reset. Pulmonary doctor put her on steroid inhaler, rescue inhaler, and nebulizer. She was still experiencing brain fog and it was better. She also reported that she could do things for 15 minutes and then would have to take a nap. The patient mentioned that she had been on the same medications for a long time. The patient reported that cardiology changed her blood pressure medication and heart medication for a short period of time since her heart rate would go up and down from 160 to 140. Pulmonary did a lot of testing and diagnosed her with bronchospasms since she would wake up in the middle of the night not being able to breathe. Thinks most of the testing was hard to get due to the COVID pandemic. She thinks that the MRI of her heart and pulmonary testing were done in Mar2021. Therapeutic measures were taken as a result of sleep apnoea syndrome. The outcome of event "brain fog started with COVID and became worse after she got the COVID vaccines" was recovering while the outcome of the remaining events was unknown.; Sender's Comments: Based on the given information and temporal association , the possible contributory role of the suspect for the event heart rate irregular , bronchospasm , Sleep apnea syndrome and increased need to sleep cannot be completely excluded. The impact of this report on the benefit-risk profile of the Pfizer product and on the conduct of the study is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.,Linked Report(s) : US-PFIZER INC-202300312736 same patient, vaccine and event; different dose;US-PFIZER INC-202300312735 same patient, vaccine and event; different dose;