Age: 51.0
Sex: F
Vaccine: VARZOS
Symptoms: Pustule, Sinusitis
Clinical narrative: missed a menstrual cycle and now is spotting this month; Nasal infection with white pustules; Nasal infection with white pustules; menstruation problems; increased heart rate; low blood sugar; numbness and redness to the left arm, left hand, and right hand/numbness in left little finger and ring finger; redness to the left arm, left hand, and right hand.; This non-serious case was reported by a consumer via call center representative and described the occurrence of numbness of upper extremities in a 51-year-old female patient who received Herpes zoster (Shingrix) (batch number FH79Y) for prophylaxis.   On 04-MAR-2024, the patient received the 1st dose of Shingrix (left deltoid) .5 ml. On 05-MAR-2024, 1 days after receiving Shingrix, the patient experienced numbness of upper extremities (Verbatim: numbness and redness to the left arm, left hand, and right hand/numbness in left little finger and ring finger) and erythema of extremities (Verbatim: redness to the left arm, left hand, and right hand.). On an unknown date, the patient experienced irregular menstruation (Verbatim: missed a menstrual cycle and now is spotting this month), pustule (Verbatim: Nasal infection with white pustules), nose infection nos (Verbatim: Nasal infection with white pustules), menstrual disorder (Verbatim: menstruation problems), heart rate increased (Verbatim: increased heart rate) and blood sugar decreased (Verbatim: low blood sugar). The patient was treated with zinc oxide and mupirocin. The outcome of the numbness of upper extremities was not resolved and the outcome of the erythema of extremities was resolved (duration 6 weeks) and the outcome of the irregular menstruation was unknown and the outcome of the pustule, nose infection nos, heart rate increased and blood sugar decreased were resolved and the outcome of the menstrual disorder was not reported.   It was unknown if the reporter considered the numbness of upper extremities, erythema of extremities, irregular menstruation, pustule, nose infection nos, menstrual disorder, heart rate increased and blood sugar decreased to be related to Shingrix.     It was unknown if the company considered the numbness of upper extremities, erythema of extremities, irregular menstruation, pustule, nose infection nos, menstrual disorder, heart rate increased and blood sugar decreased to be related to Shingrix.   Additional Information: GSK Receipt date: 06-MAY-2024 or 07-MAY-2024 The patient reported that 1 day after receiving her first dose of vaccine she had numbness and redness to the left arm, left hand, and right hand.  All resolved in approximately 6 weeks except numbness in left little finger and ring finger, numbness in left little finger and left ring finger are not resolved.  The patient treated the redness with zinc oxide and reported that after receiving dose one of vaccine she missed a menstrual cycle and now was spotting this month, also reported getting a nasal infection with white pustules after receiving the vaccine, it was unknown when infection started but infection has resolved.  The reporter interested in learning about what side effects she could have with her second dose of Shingrix which was due as a two-month time month dose today.  Her first shot caused a lot of issues, numbness and redness in her left hand and left arm, menstruation problem.  She had also reported experiencing an increased heart rate and low blood sugar a few days following the vaccination, these had resolved. The reporter wanted to know whether she should get the second shot on the day of reporting.