chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 82.0
Sex: M
Vaccine: COVID19
Symptoms: SARS-CoV-2 test positive, Septic shock
Clinical narrative: Moderna COVID-19 Vaccine EUA: COVID-19 case resulting in Hospitalization / Death. Patient received Moderna Vaccines on 1/25/2021, and 8/22/2021. Presented to ED on 12/31/2021 with complaints of shortness of breath, cough, and positive COVID test on 12/29/2021. Admitted 12/31/2022 for acute hypoxemic respiratory failure 2/2 Covid-19, intubated in the emergency department and transferred to the ICU. Patient was started on remdesivir and dexamethasone. On 1/10/2022 patient became progressively hypotensive and acidotic, developed septic shock. Expired 1/11/2022.
Age: 26.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, Vaccine breakthrough infection
Clinical narrative: Breakthrough COVID
Age: 34.0
Sex: M
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: Patient vaccinated for COVID-19 tested positive for COVID-19
Age: 43.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19
Clinical narrative: Hospitalization with covid after being fully vaccinated
Age: 83.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: COVID-19, Vaccine breakthrough infection
Clinical narrative: Fully vaccinated, not boosted.   COVID infection breakthrough with inpatient hospital stay
Age: 9.0
Sex: M
Vaccine: COVID19
Symptoms: COVID-19, Infection
Clinical narrative: Breakthrough COVID
Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Antineutrophil cytoplasmic antibody, Antinuclear antibody, Arthralgia, Blood aldosterone, Blood creatine phosphokinase
Clinical narrative: numbness and tingling of hands and fingers last 12 months now. nightly for 10 months and still 5/7 nights.  also, pain in the right shoulder developed about 2 months after the vaccination and progressed to a neuritis.  Symptoms consistent with small fiber neuropathy and brachial plexus neuritis
Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Blood iron, Blood magnesium, C-reactive protein, Full blood count, Hypoaesthesia
Clinical narrative: numbness and tingling of hands and fingers last 12 months now. nightly for 10 months and still 5/7 nights.  also, pain in the right shoulder developed about 2 months after the vaccination and progressed to a neuritis.  Symptoms consistent with small fiber neuropathy and brachial plexus neuritis
Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Laboratory test, Magnetic resonance imaging head, Magnetic resonance imaging neck, Nerve conduction studies, Neuralgic amyotrophy
Clinical narrative: numbness and tingling of hands and fingers last 12 months now. nightly for 10 months and still 5/7 nights.  also, pain in the right shoulder developed about 2 months after the vaccination and progressed to a neuritis.  Symptoms consistent with small fiber neuropathy and brachial plexus neuritis
Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Neuritis, Rheumatoid factor, SARS-CoV-2 antibody test, Serum ferritin, Small fibre neuropathy
Clinical narrative: numbness and tingling of hands and fingers last 12 months now. nightly for 10 months and still 5/7 nights.  also, pain in the right shoulder developed about 2 months after the vaccination and progressed to a neuritis.  Symptoms consistent with small fiber neuropathy and brachial plexus neuritis
Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Thyroxine, Vitamin B12
Clinical narrative: numbness and tingling of hands and fingers last 12 months now. nightly for 10 months and still 5/7 nights.  also, pain in the right shoulder developed about 2 months after the vaccination and progressed to a neuritis.  Symptoms consistent with small fiber neuropathy and brachial plexus neuritis
Age: 22.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: Patient vaccinated for COVID-19 tested positive for COVID-19.
Age: 28.0
Sex: M
Vaccine: COVID19
Symptoms: Expired product administered
Clinical narrative: Vaccine expired on 1/2/22 but still given
Age: 55.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19
Clinical narrative: hospitalization with covid after being fully vaccinated
Age: 76.0
Sex: M
Vaccine: COVID19
Symptoms: Asthenia, Chest pain, Dyspnoea, Laboratory test, Sluggishness
Clinical narrative: Chest pains and difficulty breathing. It became worse and he became extremely weak and sluggish. By Jan 1st wife took him to the ER. On the next day he under went surgery.
Age: 76.0
Sex: M
Vaccine: COVID19
Symptoms: Surgery
Clinical narrative: Chest pains and difficulty breathing. It became worse and he became extremely weak and sluggish. By Jan 1st wife took him to the ER. On the next day he under went surgery.
Age: 26.0
Sex: F
Vaccine: COVID19
Symptoms: Abdominal pain, Blood test, Computerised tomogram, Heart rate increased, Hypoaesthesia
Clinical narrative: Severe abdominal pain (lasting 7 days, hospitalized every month since October), low blood pressure (80/74),high heart rate (162), Admitted to ICU on last visit to hospital (1/22) Numbness in left leg and foot. Unofficially diagnosed with Porphyria.
Age: 26.0
Sex: F
Vaccine: COVID19
Symptoms: Hypotension, Intensive care, Porphyria, Ultrasound scan, Urine analysis
Clinical narrative: Severe abdominal pain (lasting 7 days, hospitalized every month since October), low blood pressure (80/74),high heart rate (162), Admitted to ICU on last visit to hospital (1/22) Numbness in left leg and foot. Unofficially diagnosed with Porphyria.
Age: 12.0
Sex: M
Vaccine: COVID19
Symptoms: Incorrect dose administered, No adverse event
Clinical narrative: Nurse administered Pfizer's 5-11 year of age COVID-19 vaccine to client that was 12yrs of age.  Client was monitored for 15 mins post vaccination. No acute signs and symptoms of distress noted. Client was discharged from clinic in the care of parent.
Age: 44.0
Sex: F
Vaccine: COVID19
Symptoms: Breast mass, Breast pain, Breast swelling, Mammogram abnormal, Skin warm
Clinical narrative: Breast soreness, lump, pain, swelling, warmth on right side. Began shortly after vaccine. No pain or problems prior to injection in the right arm. Symptoms have increased and remain constant. Screening Mammogram: no breast cancer detected, very dense breast tissue. During mammogram, told nurse about right breast concerns. Dr. appointment 12/15/2021: treated for mastitis with two Rx's: steroid and antibiotic. Symptoms remained. Diagnostic mammogram and ultra sound ordered and appointment scheduled for 01/26/2022.
Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: Patient vaccinated for COVID-19 tested positive for COVID-19.
Age: 55.0
Sex: F
Vaccine: COVID19
Symptoms: Headache, Joint stiffness, Musculoskeletal stiffness
Clinical narrative: headache, stiff muscles, joints ,  eyes,
Age: 39.0
Sex: M
Vaccine: COVID19
Symptoms: Pharyngeal oedema, Pharyngeal swelling
Clinical narrative: patient receive mrna vaccination.  shortly after developed posterior pharyngeal swelling and edema.  treated with epinephrine and solumedrol and resolved.
Age: 39.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Skin lesion, Urticaria
Clinical narrative: No problems with Mod doses 1 and 2. Received booster on 21 Dec 21. No problems initially. Then on 05 Jan broke out in hives all over body. No angioedema. No resp or GI problems. No evidence of IgE mediated event. 2 weeks later lesions persist. No identifiable triggers. No prior hx. Seen in ED on 13 Jan, given steroids x 3 days and Benadryl. No relief  Symptoms: URTICARIA, UNSPECIFIED.
Age: 39.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Pruritus, Rash, Urticaria
Clinical narrative: No problems with Mod doses 1 and 2. Received booster on 21 Dec 21. No problems initially. Then on 05 Jan broke out in hives all over body. No angioedema. No resp or GI problems. No evidence of IgE mediated event. 2 weeks later lesions persist. No identifiable triggers. No prior hx. Seen in ED on 13 Jan, given steroids x 3 days and Benadryl. No relief  Symptoms: URTICARIA, UNSPECIFIED.
Age: 21.0
Sex: M
Vaccine: VARZOS
Symptoms: Wrong product administered
Clinical narrative: Pt needed second dose of varicella given and dose of Shingrix was given in error
Age: 62.0
Sex: M
Vaccine: COVID19
Symptoms: Cerebrovascular accident
Clinical narrative: I had a stroke.
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Antinuclear antibody negative, Blood beta-D-glucan negative, Blood triglycerides increased, Bronchiectasis, COVID-19
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Carbon dioxide increased, Catheter placement, Chest X-ray abnormal, Chest tube insertion, Chlamydia test negative
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Cough, Cryptococcus test, Death, Endotracheal intubation, Fungal test positive
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Immunoglobulin therapy, Immunoglobulins decreased, Intensive care, Lung consolidation, Lung opacity
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Lymphadenopathy mediastinal, Mechanical ventilation, Mycoplasma test negative, Oxygen saturation decreased, Pleural effusion
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Pneumonia, Pneumonia fungal, Pneumothorax, Positive airway pressure therapy, Pyrexia
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Respiratory failure, Rheumatoid factor negative, SARS-CoV-2 test positive, Subcutaneous emphysema, Syncope
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 66.0
Sex: M
Vaccine: FLUA4
Symptoms: Thrombocytopenia, Urinary tract infection fungal
Clinical narrative: 66 yo vaccinated man with medical history notable for stage IV mantle cell lymphoma (in remission), melanoma, CKD, COVID-19, and BPH who was admitted on 12/10/21 for syncope and hypoxemic respiratory failure c/f infectious vs infl process.   Patient initially underwent induction therapy with rituximab, bendamustine, Ara-C in 8/2021 for bone marrow transplant (in anticipation of relapse), but tested positive for COVID in 8/2021. Received Regeneron at the time. Admitted 11/29-12/3 for community-acquired pneumonia and COVID pneumonia, treated with antibiotics, steroids, remdesivir. Patient present cough, fever 103.3, hypoxia. Patient initial CTA showed RLL. Started on Vanc/cefepime/doxy. Extensive pulm workup neg including beta-glucan, mycoplasma, chlamydia, crypto, cocci. Patient was retreated with remdesivir on 12/11. Second course of regeneron on 12/13. Patient weaned to 4L NC at one point, but started to have progressive worsening once the Vanc/cefepime were stopped. Patient placed back on HFNC on 12/23 and was restarted on vanc/mero/vori (+fungi in lungs/urine). Admitted to ICU on 12/27 for iNO. CXR showed worsening pneumonia R>L. CTPA on 12/27 neg for PE but with worsening consolidations and GGOs as well as bronchiectasis and small b/l pleural effusions seen. Also shown to have mediastinal adenopathy. Started on Solumedrol and Bactrim for PJP PPx. Bactrim was later transitioned to atovaquone due to thrombocytopenia and intrinsic AKI after G6PD was ruled out. Patient was between CPAP and HFNC.  Immunology consulted as Ig panel low and started on IVIG (12/28-1/1). S/p vanc course (12/22-29), meropenem (12/22-29), and voriconazole (12/23-29). ANCA, ANA, nuclear Ab panel, RF, anti-CCP, anti-GBM neg. Confirmed to be persistently COVID+ based on mRNA strand test. Patient intubated on 12/31. He was initially sedated with propofol (but developed elevated triglycerides so this was switched to dilaudid), precedex, and fentanyl (discontinued due to facility shortage). Required phenylephrine for blood pressure support. CXR showed L pneumothorax and a pigtail tube was placed. Patient desatted to 80s% on 1/1 with worsening pneumothorax on CXR so a surgical chest tube was also placed in the left lung. Both pigtail and chest tube had air leaks. Daily CXR initially showed slight improvement of pneumothorax, but subsequent CXR showed worsening pneumothorax. Patient developed subcutaneous emphysema in his neck bilaterally on 1/5. Patient also had elevated CO2, but ventilation settings were unable to be increased significantly given pneumothorax. Discussed patient's illness with family daily and family decided to change code status to DNR with no escalation of care on 1/6. After the patient's wife and children were able to visit patient, his ventilation settings were changed to room air (FiO2 21%) and phenylephrine was stopped. Patient was pronounced death at 2132 1/8/22. Family notified. As this was covid-related, death was reported to coroner
Age: 85.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: hospitalization with covid after being fully vaccinated
Age: 43.0
Sex: F
Vaccine: COVID19
Symptoms: Erythema, Influenza like illness, Mass, Pain in extremity, Pruritus
Clinical narrative: When I got the shot my arm was very pin and it hurt very bad, a few hours later my arm was red and had a lump the size of a quarter, it was swelling constantly everyday.  I also had flu like symptoms for about a day or two but they went away, I went to urgent care and they gave me an antiobiotic to take every day for seven days.  My arm was still hot and red for a few day but now it is almost back to normal, the swelling has gone down and the itchy and other things have gone away as well.
Age: 43.0
Sex: F
Vaccine: COVID19
Symptoms: Skin warm, Swelling
Clinical narrative: When I got the shot my arm was very pin and it hurt very bad, a few hours later my arm was red and had a lump the size of a quarter, it was swelling constantly everyday.  I also had flu like symptoms for about a day or two but they went away, I went to urgent care and they gave me an antiobiotic to take every day for seven days.  My arm was still hot and red for a few day but now it is almost back to normal, the swelling has gone down and the itchy and other things have gone away as well.
Age: 63.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: COVID-19, Vaccine breakthrough infection
Clinical narrative: Fully vaccinated, and boosted 1/14/22.  COVID infection breakthrough with inpatient hospital stay.
Age: 15.0
Sex: F
Vaccine: COVID19
Symptoms: Product administered to patient of inappropriate age
Clinical narrative: Pt was given a booster dose of Moderna instead of Pfizer for her age.
Age: 52.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: Patient vaccinated for COVID-19 tested positive for COVID-19.
Age: 67.0
Sex: U
Vaccine: COVID19, COVID19
Symptoms: Asymptomatic COVID-19, Coordination abnormal, Hemiparesis, SARS-CoV-2 test positive
Clinical narrative: Patient is a 68 y.o. female with a past medical history of IFG that presented to the ED this evening due to left sided weakness and decreased coordination.  Was also found incidentally to be COVID-19 positive on admission, patient asymptomatic and hemodynamically stable.
Age: 32.0
Sex: M
Vaccine: COVID19
Symptoms: Urticaria
Clinical narrative: Urticaria, reoccurring in spontaneous parts of the body. Taking over the counter antihistamine
Age: 4.0
Sex: F
Vaccine: MMRV
Symptoms: Extra dose administered
Clinical narrative: Per administering nurse, vaccines ordered were Varicella, MMR, Hep A, and Kinrix. Administering nurse gave Varicella, MMRV, Hep A, and Kinrix. Patient received 2 doses of Varicella.
Age: 44.0
Sex: F
Vaccine: COVID19
Symptoms: Dyspepsia, Rash
Clinical narrative: Full body migrating rash that is persistent.  Treatable using steroid cream and over the counter antihistamines, but symptoms persist Unexplained heartburn for 2 months.  Treatable using over the counter heartburn medication, probiotics, and temporary diet changes
Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Headache, Hypoacusis, Hypoaesthesia, Paraesthesia, Respiratory tract congestion
Clinical narrative: Started with slight ringing in my right ear. Became more congested. Had headache. After about a week I noticed tingling sensation on the right side of my face which since has become numbness now. Also had muffled hearing in my right ear. To date I have about 30 percent hearing and it hasn't improved. Very concerned I'll lose all hearing in it. Went to dr was prescribed z pack to clear it up. Didn't work.
Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Tinnitus
Clinical narrative: Started with slight ringing in my right ear. Became more congested. Had headache. After about a week I noticed tingling sensation on the right side of my face which since has become numbness now. Also had muffled hearing in my right ear. To date I have about 30 percent hearing and it hasn't improved. Very concerned I'll lose all hearing in it. Went to dr was prescribed z pack to clear it up. Didn't work.
Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Inappropriate schedule of product administration
Clinical narrative: Patient received booster vaccine on 1/18/22 (1 month too soon).  2nd dose was given on 9/14/21.
Age: 88.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Asymptomatic COVID-19, Vaccine breakthrough infection
Clinical narrative: fully vaccinated, not boosted.  Asymptomatic COVID breakthrough infection with inpatient hospital stay.
Age: 21.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: COVID-19, Infection
Clinical narrative: Breakthrough COVID 19 case.
Age: 46.0
Sex: F
Vaccine: COVID19
Symptoms: Expired product administered
Clinical narrative: Vaccine expired on 1/2/22 but still given
Age: 78.0
Sex: M
Vaccine: COVID19
Symptoms: COVID-19, Death
Clinical narrative: Patient died at medical center from Covid 19. Dose 1 given 2/25/2021 Lot #EN6198 Pfizer
Age: 68.0
Sex: M
Vaccine: COVID19
Symptoms: Alanine aminotransferase increased, Aphasia, Aspartate aminotransferase increased, Blood alkaline phosphatase increased, Confusional state
Clinical narrative: Severely elevated LFT?s ALT 1,221, AST 677, Alk Phos 244 and acute onset confusion, aphasia.
Age: 68.0
Sex: M
Vaccine: COVID19
Symptoms: Liver function test increased
Clinical narrative: Severely elevated LFT?s ALT 1,221, AST 677, Alk Phos 244 and acute onset confusion, aphasia.
Age: 16.0
Sex: M
Vaccine: COVID19
Symptoms: No adverse event, Product administered to patient of inappropriate age
Clinical narrative: Moderna was given to a patient who was not of age to receive that vaccine.  Due to the patient's age, he should have received a Pfizer vaccine.  There were no known adverse effects at the time the vaccine was given or during observation following the vaccination.
Age: 69.0
Sex: F
Vaccine: COVID19
Symptoms: Abdominal pain lower, Blood test, Coeliac disease, Colonoscopy, Computerised tomogram
Clinical narrative: Constant explosive diarrhea, pain in lower abdominal pain. Dr script for dicyclomine - nothing changed. Dr ordered that I remove dairy from my diet. I did nothing changed. Still not eating or drinking dairy products.
Age: 69.0
Sex: F
Vaccine: COVID19
Symptoms: Culture stool, Culture urine, Diarrhoea, Differential white blood cell count, Salmonellosis
Clinical narrative: Constant explosive diarrhea, pain in lower abdominal pain. Dr script for dicyclomine - nothing changed. Dr ordered that I remove dairy from my diet. I did nothing changed. Still not eating or drinking dairy products.
Age: 74.0
Sex: M
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: hospitalization with covid after being fully vaccinated with a booster
Age: 29.0
Sex: F
Vaccine: COVID19
Symptoms: Erythema, Pruritus, Urticaria
Clinical narrative: Itchy red hives all over my body
Age: 11.0
Sex: M
Vaccine: COVID19
Symptoms: Incorrect dose administered
Clinical narrative: Client and guardian lied and reported to clinic that their birthdate was in 2008 and that they were 12 years old. It has been found out later that Client was 11 at the time of vaccination.
Age: 58.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test positive
Clinical narrative: Patient fully vaccinated (Moderna x2) and admitted to Facility with positive COVID
Age: 51.0
Sex: F
Vaccine: COVID19
Symptoms: Pruritus, Rash, Rash erythematous, Rash papular
Clinical narrative: Red, raised rash (similar to hives) on right arm (vaccinated arm) and abdomen (middle, above bellybutton but below chest) appeared day after vaccination. Noticed Itching on vaccine day. Rash on arm continued to increase in size for 3-4 days. Rash on abdomen was spots about quarter-size and did not change in size. Rash was not warm to the touch and did not cause pain. Patient took Benadryl and prednisone (10mg) from previous Rx for two days. Rash has receded at time of this reporting but persisted for about 5 days total. The patient called her dermatologist and no additional instructions were given from dermatologist.
Age: 34.0
Sex: M
Vaccine: COVID19
Symptoms: Peripheral swelling, Rash, Rash erythematous, Rash pruritic
Clinical narrative: Swelling of left forefingers, itchy red rash on back of hand. Took oral benedryl on onset of symptoms. Symptoms resolving
Age: 89.0
Sex: F
Vaccine: COVID19
Symptoms: Acute respiratory failure, Atelectasis, COVID-19, COVID-19 pneumonia, Chest X-ray abnormal
Clinical narrative: Patient is fully vaccinated.  Hospitalized on 12/8/2021 for 5 days and tested + for COVID 12/8.  90-year-old female patient presented to the ED yesterday for urinary frequency. Acute Hypoxic Respiratory Failure, COVID 19 Viral Pneumonia. The patient states that she does not have any shortness of breath, cough, chest pain, nausea, vomiting, or diarrhea, though she is on 3 L of nasal cannula when assessed.  The patient states that she does not really know why she is here, though she does have a history of recurrent UTIs as well as overactive bladder with no other past medical history on file. CXR Bibasilar infiltrate or atelectasis. Treatment:  oxygen, steroids, antimicrobial, remdesivir. Discharged.
Age: 89.0
Sex: F
Vaccine: COVID19
Symptoms: Lung infiltration, Pollakiuria, SARS-CoV-2 test positive
Clinical narrative: Patient is fully vaccinated.  Hospitalized on 12/8/2021 for 5 days and tested + for COVID 12/8.  90-year-old female patient presented to the ED yesterday for urinary frequency. Acute Hypoxic Respiratory Failure, COVID 19 Viral Pneumonia. The patient states that she does not have any shortness of breath, cough, chest pain, nausea, vomiting, or diarrhea, though she is on 3 L of nasal cannula when assessed.  The patient states that she does not really know why she is here, though she does have a history of recurrent UTIs as well as overactive bladder with no other past medical history on file. CXR Bibasilar infiltrate or atelectasis. Treatment:  oxygen, steroids, antimicrobial, remdesivir. Discharged.
Age: 38.0
Sex: M
Vaccine: COVID19
Symptoms: Expired product administered
Clinical narrative: Vaccine expired on 1/2/22 but still given
Age: 41.0
Sex: F
Vaccine: COVID19
Symptoms: Amenorrhoea, Dysmenorrhoea, Heavy menstrual bleeding, Insomnia, Menstrual disorder
Clinical narrative: Insomnia (severe) lasting several weeks. Doctor prescribed sleeping and allergy meds to alleviate symptoms. Insomnia alleviated with meds within three-four weeks and without meds within eight-ten weeks.  Menstrual changes. Period arrived immediately after second shot and was not due. Period was very heavy and unusually painful. Did not have period after that for another two cycles( months.) Both incidents are out of the ordinary for me as period is usually on time and not heavy. Menstrual timing resolved itself within four-five cycles however heaviness and painfulness of periods is still an issue I did not have before this vaccine.
Age: 60.0
Sex: M
Vaccine: COVID19
Symptoms: Electrocardiogram, Electrocardiogram ambulatory, Fatigue, Palpitations
Clinical narrative: After a period of about 30 hours of feeling completely knocked out and in bed, with no fever, sore throat or muscular aches, just felt very tired, I started feeling my heart pounding very strongly while in bed or horizontal position. The feeling persisted, though I feel it is subsiding. Notwithstanding, I did go to my cardiologist and had an EKG holter installed and measures taken, I handed that holter today.
Age: 12.0
Sex: F
Vaccine: COVID19
Symptoms: Abdominal pain, COVID-19, Chills, Diarrhoea, Flushing
Clinical narrative: After second Covid vaccination patient developed catamenial anaphylaxis to Prostaglandins during menses, starting the month after vaccine.  Had a reaction (moderate) in Oct with body flushing, abdominal cramping, diarrhea. Period started 4 hours later.  November worse reaction with facial swelling/body flushing, abdominal cramping, rigors, vomiting and diarrhea.  Period started within a few hours.  December was associated with abdominal cramping and diarrhea only. Period started a few hours later.  Patient had Covid 12/25/21, mild case. January 2022 reaction was anaphylactic with facial/lip swelling, hives, rigors, abdominal cramping, nausea, vomiting and diarrhea, full body flushing.  Periods started a few hours later.  Required Benadryl 50 mg, Pepcid 40 mg, Prednisone 40 mg, Phenergan 12.5 mg and Zyrtec 10 mg (in addition to her regular dose).  4 hours later symptoms subsided.  This event is likely to continuing to occur monthly at her menses
Age: 12.0
Sex: F
Vaccine: COVID19
Symptoms: Lip swelling, Swelling face, Urticaria, Vomiting
Clinical narrative: After second Covid vaccination patient developed catamenial anaphylaxis to Prostaglandins during menses, starting the month after vaccine.  Had a reaction (moderate) in Oct with body flushing, abdominal cramping, diarrhea. Period started 4 hours later.  November worse reaction with facial swelling/body flushing, abdominal cramping, rigors, vomiting and diarrhea.  Period started within a few hours.  December was associated with abdominal cramping and diarrhea only. Period started a few hours later.  Patient had Covid 12/25/21, mild case. January 2022 reaction was anaphylactic with facial/lip swelling, hives, rigors, abdominal cramping, nausea, vomiting and diarrhea, full body flushing.  Periods started a few hours later.  Required Benadryl 50 mg, Pepcid 40 mg, Prednisone 40 mg, Phenergan 12.5 mg and Zyrtec 10 mg (in addition to her regular dose).  4 hours later symptoms subsided.  This event is likely to continuing to occur monthly at her menses
Age: 52.0
Sex: F
Vaccine: COVID19
Symptoms: Blood test normal, Cardiac stress test, Chest X-ray normal, Echocardiogram, Electrocardiogram ambulatory abnormal
Clinical narrative: I started having heart palpitations about a week after receiving the booster shot. I'm not sure of the exact date and time but there were several episodes the week of December 13, 2021. I called my primary care doctor on December 20, 2021 and the office told me to go to the Emergency Room which I did. They did an EKG, chest x-ray and blood work which was all normal. I saw a cardiologist on December 22, 2021. He did another EKG, and ordered a stress test, an echo-cardiogram, and an external mobile cardiovascular telemetry unit which showed supraventricular tachycardia (SVTs) and Premature Atrial Contractions (PACs)
Age: 52.0
Sex: F
Vaccine: COVID19
Symptoms: Electrocardiogram normal, Palpitations, Supraventricular extrasystoles, Supraventricular tachycardia
Clinical narrative: I started having heart palpitations about a week after receiving the booster shot. I'm not sure of the exact date and time but there were several episodes the week of December 13, 2021. I called my primary care doctor on December 20, 2021 and the office told me to go to the Emergency Room which I did. They did an EKG, chest x-ray and blood work which was all normal. I saw a cardiologist on December 22, 2021. He did another EKG, and ordered a stress test, an echo-cardiogram, and an external mobile cardiovascular telemetry unit which showed supraventricular tachycardia (SVTs) and Premature Atrial Contractions (PACs)
Age: 67.0
Sex: M
Vaccine: COVID19
Symptoms: Tinnitus
Clinical narrative: Tinnitus in both ears.
Age: 32.0
Sex: F
Vaccine: COVID19
Symptoms: Chest pain, Dyspnoea, Electrocardiogram, Heart rate increased
Clinical narrative: Shortness of breath, rapid heart rate, chest pain