chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 0.18
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Crying, Screaming
Clinical narrative: Mom called at 2:45 pm stating child had his shots that morning and is screaming, has given 2 doses of Tylenol and is inconsolable.  He cried for 1-2 hrs.  We suggested Tylenol every 4 hrs and a warm bath.  Call if further complications or continues.
Age: 0.2
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Crying, Diet refusal, Pain, Screaming
Clinical narrative: Onset 3/14/08-per Mom had shots in office and "screaming and crying in pain; gave Tylenol. Crying and screaming to point won't eat. Decreased appetite now and can't calm him down."
Age: 14.0
Sex: F
Vaccine: HEP, HEPA, TDAP
Symptoms: Injection site haemorrhage, Petechiae
Clinical narrative: Petechiae or extremities/ arms/legs- also ecchymosis at site of vaccination.  5/15/2008 MR received for DOS 4/04-07/2008 with DX: ITP. Pt presented bruising which started at injection sites of vaccines.  Petechiae noted on lower extremities,  chest, back, and eyelids.  Tx with IVIG and WinRho.  Pt developed h/a, neck stiffness. Clinical S&S of aseptic meningitis-likely 2' to IVIG.
Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Burning sensation, Herpes zoster, Rash vesicular
Clinical narrative: Vesicular rash (L) arm and leg that burned and resembled zoster rash.
Age: 0.2
Sex: F
Vaccine: DTAP, HEP, HIBV, IPV, PNC, RV5
Symptoms: Crying, Injection site erythema, Injection site swelling, Irritability
Clinical narrative: (R) leg redness and swelling at vaccine site patient extremely fussy and non-consolable
Age: 20.0
Sex: F
Vaccine: HPV4
Symptoms: Urticaria
Clinical narrative: Urticaria occurring 24 hours after vaccine administration.  Treated with Benadryl.
Age: 5.0
Sex: F
Vaccine: DTAP, MMR
Symptoms: Erythema, Feeling hot, Pruritus, Swelling
Clinical narrative: Redness, swelling, itching, warm to the touch radiates out greater than 6 cm from injection site.
Age: 1.1
Sex: M
Vaccine: MMR, PNC, VARCEL
Symptoms: Urticaria, Viral skin infection
Clinical narrative: Viral exanthem and urticaria on face/trunk.  No fever.
Age: 3.0
Sex: F
Vaccine: HEPA
Symptoms: Heart rate decreased, Hypotension, Pallor
Clinical narrative: This 3-year-old child received HAVRIX today, has never had a problem with same before.  She apparently seemed to have a slow heart rate and a low blood pressure and seemed somewhat ashen afterwards.  She thereafter recovered with a normal pulse and blood pressure.  She was sent here because there was concern that they were not comfortable with what had happened.  Awake, alert, happy, interactive, running around the room without difficulty.  At this time, I do not believe there are further issues that need to be addressed.  The patient was discharged with advice on follow up with her regular physician.
Age: 2.0
Sex: M
Vaccine: DTAP, HEPA
Symptoms: Erythema, Feeling hot, Induration
Clinical narrative: Mom reports positive red area and felt warm on 4/1/08.  On 4/3/08 for separate issues follow-up mom requested check of leg.  Left leg with 8 cm area of erythema and 4.75 cm area of induration.  NT, no temperature.
Age: 3.0
Sex: F
Vaccine: DTAPHEPBIP, HEPA, PNC
Symptoms: Dyskinesia, Staring
Clinical narrative: Vaccines administered, patient began staring and jerking.  Patient came to quickly, vital signs were taken.  Patients' mom reports history of seizures - not related to vaccines, no medication taken.
Age: 8.0
Sex: M
Vaccine: VARCEL
Symptoms: Erythema, Injection site papule, Swelling
Clinical narrative: Baseball size, red, swollen bump at site of VARIVAX vaccine.  Parent called office to report these concerns on 3/27/08.  Appointment was made to see patient that day but "no-showed".  Message left to inquire of condition was not returned.
Age: 12.0
Sex: M
Vaccine: HEPA, VARCEL
Symptoms: Cellulitis
Clinical narrative: Patient diagnosed with cellulitis of left arm - presented Keflex 500mg by PO BID x 10 days and to flu in 2 weeks.
Age: 0.2
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Crying, Injection site erythema, Injection site pain, Injection site swelling, Irritability
Clinical narrative: Initial report received from a health care professional on 30 March 2007.  A 2 month old, female patient was fussy, crying, with redness, 10 cm diameter swelling and pain at the injection site on the left thigh after she received Act-HIB (lot number UF015AA which corresponds to sanofi pasteur SA lot# Z08140-2), intramuscularly in the left thigh; Prevnar (Wyeth, lot number B36258F) intramuscularly in the left thigh; Pediarix (GSK, lot number AC21B096CA) intramuscularly in the right thigh and Rotateq (Merck, lot number 0023U) orally, on 28 March 2007.  She was treated with oral (po) Benadryl and cold compresses.  On 29 March 2007, she was taken to the Emergency Room (ER) with a fever 103F.  Prior to the vaccinations, on 19 March, she had a runny nose, cough and congestion - taking an antihistamine Rx.  She had no illness at the time of the vaccinations.  It was reported that the patient recovered.
Age: 0.2
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Pyrexia
Clinical narrative: Initial report received from a health care professional on 30 March 2007.  A 2 month old, female patient was fussy, crying, with redness, 10 cm diameter swelling and pain at the injection site on the left thigh after she received Act-HIB (lot number UF015AA which corresponds to sanofi pasteur SA lot# Z08140-2), intramuscularly in the left thigh; Prevnar (Wyeth, lot number B36258F) intramuscularly in the left thigh; Pediarix (GSK, lot number AC21B096CA) intramuscularly in the right thigh and Rotateq (Merck, lot number 0023U) orally, on 28 March 2007.  She was treated with oral (po) Benadryl and cold compresses.  On 29 March 2007, she was taken to the Emergency Room (ER) with a fever 103F.  Prior to the vaccinations, on 19 March, she had a runny nose, cough and congestion - taking an antihistamine Rx.  She had no illness at the time of the vaccinations.  It was reported that the patient recovered.
Sex: U
Vaccine: HIBV
Symptoms: Anorexia
Clinical narrative: This case was received from a health professional on 20 June 2007.  Two infants with no reported medical history received ActHib (lot number UE957MB).  Following vaccination, they both developed anorexia; the events had not yet resolved.  This reporter also noted that two patients experienced bowel movements after each feeding following vaccination with ActHib; this information is captured in case number 2007-02264.  Additional information regarding a patient with decreased PO intake following vaccination with ActHib can be found in case number 2007-02275.
Age: 0.2
Sex: F
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: Skin disorder
Clinical narrative: Initial report received on 07 September 2007 from a consumer's parent.  A two month-old female patient, who had no concurrent illnesses, had received a dose of ActHIB; a dose of DTaP (Trade name and manufacturer name not reported); a dose of IPOL; and a dose of "Hep B" (Trade name and manufacturer name not reported) on an unspecified day in July 2005.  The lot numbers, routes and sites of administration were not reported for any of the vaccines.  Pre-existing medical conditions and use of other medications were not reported.  The parent reported the patient developed a "skin condition" after receiving the above-mentioned vaccines, which required a doctor visit (dates not provided).  The patient had received the vaccines at two months of age and is now two years old, and her skin condition persists.  Treatment and diagnostic testings were not provided.  The reporter would not provide the contact information for the responsible physician for follow-up.  At the time of this report, the patient had not recovered.
Age: 44.0
Sex: M
Vaccine: TD
Symptoms: Arthralgia, Aspartate aminotransferase normal, Blood cholesterol increased, Blood creatine phosphokinase normal, Blood glucose normal
Clinical narrative: Developed toe joint pain and swelling approximately 1 week following receipt of Td 11/2001; progressed over next several weeks to multiple joint involvement with subsequent diagnosis of RA in 2/2002; Symptoms: Joint pain, multiple joints Start: 11/15/2001 Comment: toes, feet, ankles, right knee, right shoulder  5/9/08 Linked w/236813.  Reviewed VHC medical reocrds. FINAL DX: rheumatoid arthritis Records reveal patient experienced pain & swelling of 5th toe left foot approx 1 week after received Td booster on 11/8/2001.  Vaccination records & rheumatology records included.  Experienced sporadic migratory joint pain w/swelling involving other toes, feet, ankles, right knee, right shoulder & fingers.  Seen by PCP 2/2002 who noted synovitis.  Labs at that time were WNL but PCP clinically suspected RA & referred to rheumatology.  Seen by rheum 3/2002.  Labs at that time were ANA (+), ESR elevated.  Dx w/RA & tx aggressively w/meds & surgery.
Age: 44.0
Sex: M
Vaccine: TD
Symptoms: Blood thyroid stimulating hormone abnormal, Blood thyroid stimulating hormone decreased, Blood uric acid normal, Borrelia burgdorferi serology negative, Full blood count normal
Clinical narrative: Developed toe joint pain and swelling approximately 1 week following receipt of Td 11/2001; progressed over next several weeks to multiple joint involvement with subsequent diagnosis of RA in 2/2002; Symptoms: Joint pain, multiple joints Start: 11/15/2001 Comment: toes, feet, ankles, right knee, right shoulder  5/9/08 Linked w/236813.  Reviewed VHC medical reocrds. FINAL DX: rheumatoid arthritis Records reveal patient experienced pain & swelling of 5th toe left foot approx 1 week after received Td booster on 11/8/2001.  Vaccination records & rheumatology records included.  Experienced sporadic migratory joint pain w/swelling involving other toes, feet, ankles, right knee, right shoulder & fingers.  Seen by PCP 2/2002 who noted synovitis.  Labs at that time were WNL but PCP clinically suspected RA & referred to rheumatology.  Seen by rheum 3/2002.  Labs at that time were ANA (+), ESR elevated.  Dx w/RA & tx aggressively w/meds & surgery.
Age: 44.0
Sex: M
Vaccine: TD
Symptoms: Glycosylated haemoglobin, HIV test negative, Haemoglobin decreased, Joint swelling, Laboratory test normal
Clinical narrative: Developed toe joint pain and swelling approximately 1 week following receipt of Td 11/2001; progressed over next several weeks to multiple joint involvement with subsequent diagnosis of RA in 2/2002; Symptoms: Joint pain, multiple joints Start: 11/15/2001 Comment: toes, feet, ankles, right knee, right shoulder  5/9/08 Linked w/236813.  Reviewed VHC medical reocrds. FINAL DX: rheumatoid arthritis Records reveal patient experienced pain & swelling of 5th toe left foot approx 1 week after received Td booster on 11/8/2001.  Vaccination records & rheumatology records included.  Experienced sporadic migratory joint pain w/swelling involving other toes, feet, ankles, right knee, right shoulder & fingers.  Seen by PCP 2/2002 who noted synovitis.  Labs at that time were WNL but PCP clinically suspected RA & referred to rheumatology.  Seen by rheum 3/2002.  Labs at that time were ANA (+), ESR elevated.  Dx w/RA & tx aggressively w/meds & surgery.
Age: 44.0
Sex: M
Vaccine: TD
Symptoms: Metabolic function test normal, Prostatic specific antigen increased, Prothrombin time normal, Red blood cell sedimentation rate increased, Rheumatoid arthritis
Clinical narrative: Developed toe joint pain and swelling approximately 1 week following receipt of Td 11/2001; progressed over next several weeks to multiple joint involvement with subsequent diagnosis of RA in 2/2002; Symptoms: Joint pain, multiple joints Start: 11/15/2001 Comment: toes, feet, ankles, right knee, right shoulder  5/9/08 Linked w/236813.  Reviewed VHC medical reocrds. FINAL DX: rheumatoid arthritis Records reveal patient experienced pain & swelling of 5th toe left foot approx 1 week after received Td booster on 11/8/2001.  Vaccination records & rheumatology records included.  Experienced sporadic migratory joint pain w/swelling involving other toes, feet, ankles, right knee, right shoulder & fingers.  Seen by PCP 2/2002 who noted synovitis.  Labs at that time were WNL but PCP clinically suspected RA & referred to rheumatology.  Seen by rheum 3/2002.  Labs at that time were ANA (+), ESR elevated.  Dx w/RA & tx aggressively w/meds & surgery.
Age: 44.0
Sex: M
Vaccine: TD
Symptoms: Rheumatoid factor negative, Syphilis test negative, Urine analysis normal, X-ray abnormal
Clinical narrative: Developed toe joint pain and swelling approximately 1 week following receipt of Td 11/2001; progressed over next several weeks to multiple joint involvement with subsequent diagnosis of RA in 2/2002; Symptoms: Joint pain, multiple joints Start: 11/15/2001 Comment: toes, feet, ankles, right knee, right shoulder  5/9/08 Linked w/236813.  Reviewed VHC medical reocrds. FINAL DX: rheumatoid arthritis Records reveal patient experienced pain & swelling of 5th toe left foot approx 1 week after received Td booster on 11/8/2001.  Vaccination records & rheumatology records included.  Experienced sporadic migratory joint pain w/swelling involving other toes, feet, ankles, right knee, right shoulder & fingers.  Seen by PCP 2/2002 who noted synovitis.  Labs at that time were WNL but PCP clinically suspected RA & referred to rheumatology.  Seen by rheum 3/2002.  Labs at that time were ANA (+), ESR elevated.  Dx w/RA & tx aggressively w/meds & surgery.
Age: 29.0
Sex: M
Vaccine: TYP
Symptoms: Cough, Headache, Myalgia, Pharyngolaryngeal pain, Pyrexia
Clinical narrative: Otherwise healthy 29y M developed severe generalized headache and fever to 104.8F lasting over 48h after third and fourth doses of oral typhoid vaccine by Vivotif Berna. However, also had cough, myalgias and sore throat during this time.
Age: 20.0
Sex: F
Vaccine: HPV4
Symptoms: Autoimmune disorder, Computerised tomogram abnormal, Demyelination, Hypoaesthesia, Inflammation
Clinical narrative: Initial and follow-up information has been received from a physician concerning a 20 year old female student with allergies to amoxicillin, nickel, silver, and gold, who, on 22-JAN-2008 was vaccinated in the left deltoid with her first dose of Gardasil (lot# 659657/1487U). There were no illnesses at the time of the vaccination. Subsequently the patient experienced neurological symptoms and numbness down her arm 2 weeks after receiving the vaccine. On 14-FEB-2008 the patient experienced a sudden onset of decreased vision in her right eye that persisted. The patient was referred to a neurologist. An magnetic resonance imaging (MRI) was performed and was consistent with demyelinating disease. A lumbar puncture was performed and was consistent with inflammation. A computed axial tomography scan (CT) showed white spots on her brain, indicative of an autoimmune reaction. The patient was diagnosed with acute central nervous system demyelinating type inflammatory disease, three weeks after her first dose of Gardasil (Lot# 659657/1487U). At the time of the report, the patient had not recovered. The physician considered the acute central nervous system demyelinating type inflammatory disease, and decreased vision in the right eye to be disabling. This is one of two reports from the same source. Additional information is not expected.   4/28/2008 Neuro eval of 4/21/2008 received. Pt reports onset of decreased vision in the R eye which worsened over the following few days. Some pain reported when looking to extreme right or left. Seen for ophth consult 3/25/08 with DX: Acute viral keratoconjunctivitis. Seen in F/U by Neuro 4/2/08 with c/o tingling in the R upper and lower extremities and gait disturbance affecting the R lower extremity. Improvement noted with medrol dose pack.  DX:  Demyelinating disease NOS, either due to recent Gardasil vax or MS
Age: 20.0
Sex: F
Vaccine: HPV4
Symptoms: Lumbar puncture abnormal, Neurological symptom, Nuclear magnetic resonance imaging brain abnormal, Visual acuity reduced
Clinical narrative: Initial and follow-up information has been received from a physician concerning a 20 year old female student with allergies to amoxicillin, nickel, silver, and gold, who, on 22-JAN-2008 was vaccinated in the left deltoid with her first dose of Gardasil (lot# 659657/1487U). There were no illnesses at the time of the vaccination. Subsequently the patient experienced neurological symptoms and numbness down her arm 2 weeks after receiving the vaccine. On 14-FEB-2008 the patient experienced a sudden onset of decreased vision in her right eye that persisted. The patient was referred to a neurologist. An magnetic resonance imaging (MRI) was performed and was consistent with demyelinating disease. A lumbar puncture was performed and was consistent with inflammation. A computed axial tomography scan (CT) showed white spots on her brain, indicative of an autoimmune reaction. The patient was diagnosed with acute central nervous system demyelinating type inflammatory disease, three weeks after her first dose of Gardasil (Lot# 659657/1487U). At the time of the report, the patient had not recovered. The physician considered the acute central nervous system demyelinating type inflammatory disease, and decreased vision in the right eye to be disabling. This is one of two reports from the same source. Additional information is not expected.   4/28/2008 Neuro eval of 4/21/2008 received. Pt reports onset of decreased vision in the R eye which worsened over the following few days. Some pain reported when looking to extreme right or left. Seen for ophth consult 3/25/08 with DX: Acute viral keratoconjunctivitis. Seen in F/U by Neuro 4/2/08 with c/o tingling in the R upper and lower extremities and gait disturbance affecting the R lower extremity. Improvement noted with medrol dose pack.  DX:  Demyelinating disease NOS, either due to recent Gardasil vax or MS
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP
Symptoms: Drug exposure during pregnancy, Influenza, Laboratory test, Ultrasound scan
Clinical narrative: Information has been received for the Merck Pregnancy Registry for GARDASIL from a 22 year old female consumer with no pertinent medical history or drug reactions/allergies who on 18-DEC-2007 was vaccinated with a first dose of GARDASIL injection. Concomitant therapy included diphtheria toxoid (+) pertussis acellular vaccine (unspecified) (+) tetanus toxoid. The consumer reported that she received the first dose of GARDASIL while she was pregnant. The consumers LMP was 13-NOV-2007. The caller was admitted to the hospital overnight for 1 day for the flu. Medical attention was sought. There was no side effects reported as a result of her getting the dose of GARDASIL. On an unspecified date the patient had a diagnostic laboratory test and an ultrasound performed. Results were not given. The estimated date of delivery is 19-AUG-2008. No additional information was given. Additional information has been requested.
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Chest X-ray normal, Convulsion, Cough, Diarrhoea, Irritability
Clinical narrative: Information has been received from a consumer concerning her 12 month old son with a history of wheezing who in March 2008, was placed on therapy with MMR II (dose, duration and indication not reported).  Concomitant therapy included VARIVAX.  On approximately 21-MAR-2008 the patient developed diarrhea and coughing.  On 23-MAR-2008 the patient experienced irritability, fever.  The patient was examined by a health care provider and was noted to have a red throat with white plaques and fluid behind his eardrums.  The patient was started on amoxicillin.  Later that evening, the patient experienced two twitching motions while feeding which progressed to a generalized seizure (lasting two minutes) with fever.  The patient was evaluated in an emergency department where he was noted to have slight rales in one area of his lungs on auscultation and a red throat with white plaques.  A rapid streptococcus test was negative.  Chest x-ray did not note pneumonia.  The patient improved with antipyretics and was discharged from the emergency department.  It was also noted that the family history was significant for a brother with a history of febrile seizures.  Upon internal review it was determined that febrile seizure was an other important medical event.  Additional information has been requested.
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Middle ear effusion, Muscle twitching, Pharyngeal erythema, Pyrexia, Rales
Clinical narrative: Information has been received from a consumer concerning her 12 month old son with a history of wheezing who in March 2008, was placed on therapy with MMR II (dose, duration and indication not reported).  Concomitant therapy included VARIVAX.  On approximately 21-MAR-2008 the patient developed diarrhea and coughing.  On 23-MAR-2008 the patient experienced irritability, fever.  The patient was examined by a health care provider and was noted to have a red throat with white plaques and fluid behind his eardrums.  The patient was started on amoxicillin.  Later that evening, the patient experienced two twitching motions while feeding which progressed to a generalized seizure (lasting two minutes) with fever.  The patient was evaluated in an emergency department where he was noted to have slight rales in one area of his lungs on auscultation and a red throat with white plaques.  A rapid streptococcus test was negative.  Chest x-ray did not note pneumonia.  The patient improved with antipyretics and was discharged from the emergency department.  It was also noted that the family history was significant for a brother with a history of febrile seizures.  Upon internal review it was determined that febrile seizure was an other important medical event.  Additional information has been requested.
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Streptococcal identification test, Streptococcal identification test negative, Throat lesion
Clinical narrative: Information has been received from a consumer concerning her 12 month old son with a history of wheezing who in March 2008, was placed on therapy with MMR II (dose, duration and indication not reported).  Concomitant therapy included VARIVAX.  On approximately 21-MAR-2008 the patient developed diarrhea and coughing.  On 23-MAR-2008 the patient experienced irritability, fever.  The patient was examined by a health care provider and was noted to have a red throat with white plaques and fluid behind his eardrums.  The patient was started on amoxicillin.  Later that evening, the patient experienced two twitching motions while feeding which progressed to a generalized seizure (lasting two minutes) with fever.  The patient was evaluated in an emergency department where he was noted to have slight rales in one area of his lungs on auscultation and a red throat with white plaques.  A rapid streptococcus test was negative.  Chest x-ray did not note pneumonia.  The patient improved with antipyretics and was discharged from the emergency department.  It was also noted that the family history was significant for a brother with a history of febrile seizures.  Upon internal review it was determined that febrile seizure was an other important medical event.  Additional information has been requested.
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Chest pain, Dyspnoea, Gait disturbance, Hemiparesis, Hypoaesthesia
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Oedema peripheral, Swelling face
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Cardiolipin antibody negative, Chest X-ray normal, Chest pain, Computerised tomogram normal, Depressed level of consciousness
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Echocardiogram, Electrocardiogram normal, Factor V Leiden mutation, Hemiparesis, Hypoaesthesia
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Inappropriate schedule of drug administration, Lipoprotein (a) increased, Nuclear magnetic resonance imaging brain normal, Polymerase chain reaction, Protein S normal
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Scan brain, Swelling face, Type I hypersensitivity, Ultrasound Doppler normal, Ultrasound scan normal
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Blood cholesterol increased, Chest pain, Dyspnoea, Hypoaesthesia, Laboratory test normal
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 15.0
Sex: F
Vaccine: HEPA, MNQ, TDAP, HEPA, MNQ, TDAP, HEPA, MNQ, TDAP
Symptoms: Muscular weakness, Swelling face
Clinical narrative: Shortness of breath, chest pain 1 hour after shots were given. 5 hours after shots right side of face swells right arm and hand swells. 9 hours after shots whole right side of body numb weak and swollen not able to walk with out help.  4/25/08 Reviewed hospital medical records of 3/28-4/2/2008. FINAL DX: Lower extremity weakness.  Neuro consult stated probable conversion disorder.  ID consult stated probable Type 1 hypersensitivity reaction. Records reveal patient experienced sudden onset chest pain & SOB.  Did not resolve w/NSAIDS.  Awoke from sleep w/swelling right side face, weakness & numbness or right side, ambulating w/limp, HA, heavy feeling pain, fatigue.  Exam revealed droopy eyes, right arm/leg weakness w/dininished sensation, weak right hand grip.  Neuro, ID & cardio consults done.  Improved & d/c to home w/continued PT. Follow-up: August 13, 2008-Conversation with patient's mother. Patient is doing somewhat better. Can now walk without cane. Still some numbness-more tingly-"like feeling trying to come back". Still in physical therapy three times per week. Nerve conduction studies-normal. Patient's primary care physician has now been changed. (Since patient has not been in our office since March 28, 2008, more recent information could probably be obtained from Dr. Mother states that an egg allergy was noted in patient at an outing in May, 2008. After eating spinach dip which contained egg, she developed shortness of breath, chest pain, and weakness, which resembled her reaction after the immunizations. A similar reaction occurred later when she ingested eggs again. She has not been offered eggs since then. Patient's working diagnosis as of the time she was last seen in our office is a "probable Type I Hypersensitivity Reaction secondary to an immunization."
Age: 21.0
Sex: F
Vaccine: HPV4
Symptoms: Dizziness, Nausea
Clinical narrative: c/o nausea and lightheadedness after injection given. Was fine after about 20 minutes.
Age: 54.0
Sex: F
Vaccine: PPV
Symptoms: Body temperature increased, Chills, Injection site erythema, Injection site induration, Injection site pain
Clinical narrative: Injection site Red, Hard, Warm Area, appeared approx two days after injecction. Pt also reports chills, temp of 99 po, pain at site.  Pt advised to place warm compress on site, gentle ROM, Tylenol for pain and to return to clinic if not improving.
Age: 54.0
Sex: F
Vaccine: PPV
Symptoms: Injection site warmth
Clinical narrative: Injection site Red, Hard, Warm Area, appeared approx two days after injecction. Pt also reports chills, temp of 99 po, pain at site.  Pt advised to place warm compress on site, gentle ROM, Tylenol for pain and to return to clinic if not improving.
Age: 56.0
Sex: M
Vaccine: RAB
Symptoms: Fatigue, Pain, Pallor
Clinical narrative: Approx 1 hr after 3rd human diploid cell rabies vaccine, became extremely fatigued with aches, chiefly in legs and low back.  2 hr after vaccine reported to our clinic.  Looked pale.  BP was 180/110.  Placed in bed to rest for 1 hr and symptoms seem to resolve, except BP remained elevated at 166/103.  To be followed.
Age: 49.0
Sex: M
Vaccine: DTAP
Symptoms: Chills, Dyskinesia, Pyrexia
Clinical narrative: Woke nite after admin of vaccine with arm pounding, and chills, subnormal fever. In am had chills, and fever 101.5.  No redness at site of inject.  Pt to push fluids and use Tylenol.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Anaphylactic reaction, Cough, Eyelid oedema, Lacrimal disorder, Lip swelling
Clinical narrative: Patient had an anaphylactic reaction after receving her 4 year old vaccines. She experienced lacrimation, coughing, hives, subcutaneous edema, mild stridor, lip and eye lid swelling. She required oral Benadryl and subcutaneous epinephrine and then was sent to the ER for further observation.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Oedema, Stridor, Urticaria
Clinical narrative: Patient had an anaphylactic reaction after receving her 4 year old vaccines. She experienced lacrimation, coughing, hives, subcutaneous edema, mild stridor, lip and eye lid swelling. She required oral Benadryl and subcutaneous epinephrine and then was sent to the ER for further observation.
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Patient was seen for her well child exam on 4/3/2008 at 9am.  She received her DTaP vaccine in her left deltoid.  The following morning on 4/4/08, she woke up and had erythema and swelling at this site, measuring 7 by 7 cm on my examination today.  The site was round, well-circumscribed, and mildly tender to palpation.  Her temperature in the office was 99.6F.  She was otherwise well appearing and discharged home from the office with symptomatic care for this immunization reaction (Tylenol or Motrin for discomfort, cool compresses, recheck next week if not resolving).
Age: 8.0
Sex: F
Vaccine: VARCEL
Symptoms: Erythema, Induration, Injection site erythema, Injection site swelling, Injection site vesicles
Clinical narrative: Day after vaccine given, pt noticed red, swollen area near injection site.  Phoned in for advise and told to ice, give Tylenol and call if rash worsens.  Was seen in clinic 2 days after receiving vaccine--had 11cm x 14cm indurated, red, swollen area to left upper outer arm.  There was also a cluster of vesicles 2cm x 3cm near injection site.
Age: 8.0
Sex: F
Vaccine: VARCEL
Symptoms: Oedema peripheral, Rash
Clinical narrative: Day after vaccine given, pt noticed red, swollen area near injection site.  Phoned in for advise and told to ice, give Tylenol and call if rash worsens.  Was seen in clinic 2 days after receiving vaccine--had 11cm x 14cm indurated, red, swollen area to left upper outer arm.  There was also a cluster of vesicles 2cm x 3cm near injection site.
Age: 13.0
Sex: F
Vaccine: HEPA, HPVX
Symptoms: Back pain, Vomiting
Clinical narrative: Patient received the third dose of HPV and her second dose of Hepatitis A yesterday, April 3, 2008, around 3:30 p.m.  She was feeling totally fine, no problems.  On Friday, April 4, 2008, I received a call from her school to pick her up due to vomiting and lower back pain. She left for school feeling fine and I received the call about one hour later-8:45a.m.
Age: 44.0
Sex: F
Vaccine: TDAP
Symptoms: Headache, Nausea, Pain, Pyrexia, Vomiting
Clinical narrative: High fever - 103 degrees, body aches, headache, nausea and vomiting within 24 hours of administration.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site inflammation, Injection site irritation, Injection site pruritus, Oedema peripheral
Clinical narrative: Pt. reported that injection site was red and inflamed by the time she got home (about 30 minutes) from clinic.  Next day site/surrounding area became more itchy and irritated.  by 2 days post inj. (Sat.) arm was red and swollen from shoulder to elbow.  It was itchy, not painful.  She had no systemic complaints.  No hives, no other symptoms of adverse reaction. Saw her own MD  on Day 4 (Monday.  Used Caladryl on site for comfort through days 1-3.  Stopped this on advice of MD on Day 4.  Called vaccine administrator on Day - still had reddened area she reported as about 6 inches in diameter around injection site.  Advised to seek further medical evaluation if condition did not continue to improve.  Reported signs of all local reaction had resolved in about 1 week.
Age: 0.3
Sex: M
Vaccine: RV5
Symptoms: Apnoea, Gaze palsy, Loss of consciousness
Clinical narrative: Rotavirus 2nd dose given. 20 min later, unconscious, stopped breathing, eyes rolling in back of head.  5/9/08 Reviewed hospital medical records of 1/14-1/16/2008. FINAL DX: cyanotic episode; sacral dimple; heart murmur. Records reveal patient experienced 3-4 min episode of decreased responsiveness w/pallor & circumoral cyanosis.  Returned to normal state w/n 15-20 min.  Stable throughout hospitalization w/o further episode of apnea.
Age: 79.0
Sex: F
Vaccine: VARZOS
Symptoms: Acute respiratory failure, Antinuclear antibody positive, Blood creatinine increased, Blood immunoglobulin A increased, Blood immunoglobulin G normal
Clinical narrative: Pt presented to PCP on 12/6/07 with 2d hx N/V and 1.5 wk hx gen. malaise. Chem 7 revealed ARF and pt admitted on 12/6/07. Pt hydrated and on 12/8/07 had rapid resp. decompensation requiring intubation. No renal biopsy obtained but final diagnosis rapidly progressing glomerular nephritis w/no response to steroids. 1/20/2010 Patient still requires dialysis-no appreciable improvement in GFR. Follow-up: Patient continues to have ERSD requiring hemodialysis 3x /wk. Pt still wishes not to provide identifying information. However, if any further cases are reported, please contact me and I will speak with the patient again.
Age: 79.0
Sex: F
Vaccine: VARZOS
Symptoms: Blood immunoglobulin M decreased, Blood urea increased, Complement factor C3 decreased, Complement factor C4 decreased, Dialysis
Clinical narrative: Pt presented to PCP on 12/6/07 with 2d hx N/V and 1.5 wk hx gen. malaise. Chem 7 revealed ARF and pt admitted on 12/6/07. Pt hydrated and on 12/8/07 had rapid resp. decompensation requiring intubation. No renal biopsy obtained but final diagnosis rapidly progressing glomerular nephritis w/no response to steroids. 1/20/2010 Patient still requires dialysis-no appreciable improvement in GFR. Follow-up: Patient continues to have ERSD requiring hemodialysis 3x /wk. Pt still wishes not to provide identifying information. However, if any further cases are reported, please contact me and I will speak with the patient again.
Age: 79.0
Sex: F
Vaccine: VARZOS
Symptoms: Endotracheal intubation, Glomerular filtration rate decreased, Glomerulonephritis, Haemodialysis, Malaise
Clinical narrative: Pt presented to PCP on 12/6/07 with 2d hx N/V and 1.5 wk hx gen. malaise. Chem 7 revealed ARF and pt admitted on 12/6/07. Pt hydrated and on 12/8/07 had rapid resp. decompensation requiring intubation. No renal biopsy obtained but final diagnosis rapidly progressing glomerular nephritis w/no response to steroids. 1/20/2010 Patient still requires dialysis-no appreciable improvement in GFR. Follow-up: Patient continues to have ERSD requiring hemodialysis 3x /wk. Pt still wishes not to provide identifying information. However, if any further cases are reported, please contact me and I will speak with the patient again.
Age: 79.0
Sex: F
Vaccine: VARZOS
Symptoms: Nausea, Renal failure acute, Renal failure chronic, Respiratory depression, Vomiting
Clinical narrative: Pt presented to PCP on 12/6/07 with 2d hx N/V and 1.5 wk hx gen. malaise. Chem 7 revealed ARF and pt admitted on 12/6/07. Pt hydrated and on 12/8/07 had rapid resp. decompensation requiring intubation. No renal biopsy obtained but final diagnosis rapidly progressing glomerular nephritis w/no response to steroids. 1/20/2010 Patient still requires dialysis-no appreciable improvement in GFR. Follow-up: Patient continues to have ERSD requiring hemodialysis 3x /wk. Pt still wishes not to provide identifying information. However, if any further cases are reported, please contact me and I will speak with the patient again.