Sex: F
Vaccine: HPV4
Symptoms: Postural orthostatic tachycardia syndrome, Tremor, Upper respiratory tract infection
Clinical narrative: ended up with CDIFF; flu like symptoms; She got mono due to low immune system; She was diagnosed with POTS; Now has chronic nerve damage; a really bad tremor to her right hand; feeling bad kinda like after a flu shot; fatigued; cold; Upper respiratory infection; Pneumonia; This spontaneous report has been received from a consumer referring to her daughter, a female patient of unknown age. The patient's medical history included postural orthostatic tachycardia syndrome. Information regarding the patient's drug reactions or allergies, concurrent conditions and concomitant medications was not provided.    On an unspecified date in 2007, the patient was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) (strength, dose, route, frequency, anatomical location, lot # and expiration date were not provided) for prophylaxis.  It was reported that after the first shot, on an unknown date, the patient had some adverse reactions, feeling bad like after a flu shot (feeling abnormal), fatigued. The patient had cold, then upper respiratory infection and then pneumonia.  On an unknown date, the patient was vaccinated with the second and third dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) (strength, dose, route, frequency, anatomical location, lot # and expiration date were not provided) for prophylaxis.  By the time the patient got the third dose she had to see the doctor 14 times in 1 year due to colds, pneumonia, and flu like symptoms. It was mentioned that because of the administration of antibiotics, the patient ended up with CDIFF (clostridium difficile colitis) putting her in emergency room.   On an unknown date, the patient developed "mono" due to low immune system (infectious mononucleosis). On an unknown date, the patient had blood work done one day and she called home crying and saying she could not breathe, her  heart was pounding out of chest, so she was sent to ER, then, in March 2020, the patient was diagnosed with POTS (postural orthostatic tachycardia syndrome) and was sent to a cardiologist. It was also reported that the patient used to be vivacious and now has chronic nerve damage (nerve injury), a really bad tremor to her right hand (tremor), and flare ups all the time. The reporter also asked if there was any type of compensation that can be given at this point, because her daughter was 25 now and she can not hold down a job, "she spends a lot of time too tired to do anything and this is going to be the way it is for the rest other life. I am frustrated and hurt that I did not do more research and did not know that this might happen". At the reporting time, the outcome of pneumonia, tremor, nerve injury, postural orthostatic tachycardia syndrome, infectious mononucleosis, influenza like illness, upper respiratory tract infection, nasopharyngitis, fatigue, feeling abnormal and clostridium difficile colitis was reported as not resolved.  Upon internal review, pneumonia and clostridium difficile colitis were determined to be medically significant.