Age: 66.0
Sex: F
Vaccine: COVID19
Symptoms: Red blood cell abnormality, Red blood cell count, Red blood cell count decreased, Reticulocyte count
Clinical narrative: immature red blood cells that are produced in the bone marrow; the number dropped/the red blood count dropped; This spontaneous case was reported by a patient and describes the occurrence of RED BLOOD CELL ABNORMALITY (immature red blood cells that are produced in the bone marrow) and RED BLOOD CELL COUNT DECREASED (the number dropped/the red blood count dropped) in a 66-year-old female patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis.     The patient's past medical history included COVID-19. Previously administered products included for Product used for unknown indication: Pfizer COVID-19 Vaccine in 2022. Past adverse reactions to the above products included COVID-19 with Pfizer COVID-19 Vaccine. Concurrent medical conditions included Anemia.    On 03-Oct-2024, the patient received dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (unknown route) .5 milliliter. On 12-Oct-2024, the patient experienced RED BLOOD CELL ABNORMALITY (immature red blood cells that are produced in the bone marrow) and RED BLOOD CELL COUNT DECREASED (the number dropped/the red blood count dropped). At the time of the report, RED BLOOD CELL ABNORMALITY (immature red blood cells that are produced in the bone marrow) and RED BLOOD CELL COUNT DECREASED (the number dropped/the red blood count dropped) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In July 2024, Red blood cell count: Normal. In July 2024, Reticulocyte count: Normal. On 12-Oct-2024, Red blood cell count: three months later, the red blood count dropped.     For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Unknown), the reporter did not provide any causality assessments.   It was reported that patient did not receive any other vaccines in the 4 weeks prior to COVID-19 vaccine. The concomitant medication was not reported by reporter. It was reported that patient did see a hematologist every couple of months. She just saw him this morning and she had blood work done every couple of months. She never had chemotherapy or anything like that. It was also reported that she does not had cancer. She got the vaccine on 03rd October Thursday, and on Friday, 11th October patient had her blood test done and she saw, and the doctor saw that the bone marrow, the number of the immature red blood cells that are produced in the bone marrow, the number dropped, it dropped significantly (lab results were received on 12-Oct-2024). She said no, she had been run down. She had not been sick, but she did get the COVID vaccine. He said the vaccine could affect the blood counts and the bone marrow. Patient saw her hematologist back in like the first week of July and the numbers, the red blood count, the reticulocyte count, which was the number of immature baby red blood cells that were created or produced in the bone marrow. All that was normal. They were on the normal range. Now, three months later, the red blood count dropped. Patient chose Moderna over Pfizer because two years ago, she got the Pfizer booster whatever the bivalent or whatever, whatever it was. And two weeks later, she got COVID. The treatment medication was not reported by reporter.