Age: 82.0
Sex: F
Vaccine: FLU3
Symptoms: Cerebrovascular accident, Dysarthria, Joint range of motion decreased, Salivary hypersecretion
Clinical narrative: A report was received from a health care professional on 12/17/02 concerning a 82 year old female vaccinee who experienced slurred speech, increased saliva production, and was unable to lift her arm 20 minutes after receiving Fluvirin and required treatment in the ER on 11/18/02. The event was considered medically significant (OMIC). Concomitant medication reported included digoxin, thyroxine sodium, liothyronine sodium, doxepin hydrochloride, klonopin, zolpidem tartrate and trazodone hydrochloride. It was reported that the vaccinee had also received virus influenza (brand unspecified) on 11/1/02. The pt has a history of lung cancer, hypothyroidism, polyarthralgia, incomplete right bundle branch block and mild mitral valve regurgitation. On 11/15/02 the vaccinee experienced symptoms which the reporter felt were consistent with cerebral vascular accident (CVA). Symptoms reported included slurred speech, increrased soliva production and episodes whereby the vaccinee was unable to lift her arm. It was also reported that the vaccinee did not experience a rash, itching or throat tightening. The vaccinee was referred to a hospital ER on the 11/16/02 in order to rule out a CVA as per the reporter. It was reported that the vaccinee underwent a normal neurological examination in the ER of the hospital. It was reported that the vaccinee had recovered at the time of the report. The reporter has assesed the relationship of the vaccine to the event as unclassified.  Follow up on 01/29/2003: "A follow up report was received from a health care professional.  The vaccinee received a 0.25ml Fluvizin booster intramuscularly into the left deltoid.  Additional concomitant medication reported included vezopomil, nystatin, testostelone, progesterone, vitamin B12, and sortesline.  The vaccinee has a past medical history of lung caner which began in 1967, incomplete right bundle branch block, lone paroxysmal atrial fibrillation, chronic fatigue, fibromyalgia, immune deficiency, valve regurgitation, insomnia, depression and hypertension.  The vaccinee has an allergy to penicillin and "other medications".  The vaccinee also had mild tricuspid valve regurgatation (previously reported as mitral).  The vaccinee requested to receive a flu vaccine in a divided dose, 2 weeks apart.  The vaccinee initially received 0.25ml influenza virus (brand unspecified) on 10/31/2002 followed by a booster of 0.25ml flovirin on 11/15/2002. The vaccines was admitted to an emergency room with acute onset of slurred speech and a "thick tongue" approximately five minutes after vaccination.  The vaccinee denied any other acute complaints.  Upon physical examination the vaccinee had blood pressure of 126/61mm/Hg and a pulse of 81 beats/minutes.  The vaccinee was also reported to be anxious.  There were no cartid bruits and coronae examination indicated a regular rate and rhythm without any murmurs.  Neurological examination indicated all granial nerves through to MII were intact with the exeption of some very slight dysphasis.  The vaccinee's gait was within normal limits.  Fromberg test was reported as negative.  the vaccinee's electrocardiogram indicated normal sinus rhythem at 68 beats per minute with left atrial enlargement and an incomplete right bundle branch block.  This was reported as unchanged from a previous electrocardiogram taken on 03/19/2001, CBC, Coagulation, CPK and treponin I were all reported as normal.  Digoxin was reported to be in the therapeutic range.  The reporter assessed the speech difficulties to be of unclear etiology.  The reporter indicated that the vaccinee was instructed to continue her current medications no previously prescribed and to follow up with her PCP.  The vaccinee was discharged from hospital on 11/18/2002.  The reporter assessed the causal relationship of the event to fluvirin for saliva production, slurred speech, and inability to lift arm as possibly related, and impaired gait as unclassifiable.  The other event's causality were not reported."