Sex: F
Vaccine: UNK
Symptoms: Neurological symptom, Neuropathy peripheral, Pain, Pruritus, SARS-CoV-2 antibody test negative
Clinical narrative: weakness; tremors; couldn't tap the phone with her right hand; melted into chair; Shooting pain; numbness; pruritus; fell; had GBS; lymphedama; Acute onset neurological; neuropathy / couldn't raise her head or arms / slumpimg; slurring / couldn't talk; This case was reported by a other health professional via call center representative and described the occurrence of guillain barre syndrome in a female patient who received Flu Seasonal QIV Quebec (FluLaval Quadrivalent 2016-2017 season) for prophylaxis.   On an unknown date, the patient received FluLaval Quadrivalent 2016-2017 season. On 13th January 2020, more than 2 years after receiving FluLaval Quadrivalent 2016-2017 season, the patient experienced neuropathy (serious criteria GSK medically significant). On an unknown date, the patient experienced guillain barre syndrome (serious criteria GSK medically significant), lymphedema, neurological symptom, slurred speech, weakness, tremor, mobility decreased, feeling hot, shooting pain, numbness, pruritus and fall. On an unknown date, the outcome of the guillain barre syndrome, lymphedema, neurological symptom and weakness were not recovered/not resolved and the outcome of the neuropathy, tremor, mobility decreased, feeling hot, shooting pain, numbness, pruritus and fall were unknown and the outcome of the slurred speech was recovered/resolved.   It was unknown if the reporter considered the guillain barre syndrome, neuropathy, lymphedema, neurological symptom, slurred speech, weakness, tremor, mobility decreased, feeling hot, shooting pain, numbness, pruritus and fall to be related to FluLaval Quadrivalent 2016-2017 season.  Additional information was provided as follows: The age at vaccination was not reported. The patient lkely had GBS(guillain barre syndrome) reaction to Flulaval 2016-2017 which was acute and complicated. The patient experienced acute onset neurological and lymphedama 16 hrs post vaccination. It took 5 months for symtoms to resolve. 4th-5th January 2020, the patient experienced acute onset similar symptoms which were ongoing. The patient had a suspect exposure to Covid 19 in December 21, 2019. The symptoms began 13 days later including peripheral neuropathy all 4 limbs, severe lyphedema requiring bilateral carpal tunnel surgeries. The patient had persistent shooting pains, numbness, intense pruritus and other. In mid May 2020, the patient tested for Covid AG and AB, result was negative, unknown which manufacturer made tests. The patient stated that she suspected shouldn't get Flulaval Quad again. The patient wanted to know What was the position on She getting Covid vaccine considering severity of adverse run to Flulaval in 2016. The patient would see immunologist day after reporting 3pm MST. The patient stated that she did not want to be one of those patients who stupidly got another rabies vaccine then went on to develop an autoimmune disease. She at time of reporting hd an autoimmune disease from the flu vaccine. With regard to her experience following Flulaval, she stated she was sitting there and felt like she melted into chair. She couldn't talk. She was slurring.  The patient couldn't raise her head or arms. She fell out of bed. The neuropathy went on for a while. The symptom of slurring pretty well resolved within 48 hours. The weakness still persisted occasionally. She experienced tremors. This time around she did not have tremors but the neuropathy was ridiculous. The patient finally saw a neurologist. She first talked to them in Jan 2017 and finally saw him 2 to 3 weeks before reporting. She did not know. She said it was idiopathic. She had to retire as a result and has had no paycheck since 2019. Her take was that she visited a large aquarium 4 days before Christmas in 2019.  13 to14 days later she experienced virtually that same symptoms as she had 16 hours post flu vaccine, however that time it was much more, maybe another 25 to 30 percent neurologic, the slurring and slumping. The patient couldn't tap the phone with her right hand to call her internist. She had to use her left hand. And tremors persisted. She had to quit doing surgeries. Fast forward symptoms kind of resolved in terms of fine motor things and no tremors. She had to get injections in her thumbs 6x because of the lymphedema. The reporter was not sure if it was due to exposure to the virus (COVID) or vaccine.  The physicians she had been seeing have been contradicting each other. The reporter consented to follow up.