Sex: M
Vaccine: COVID19, COVID19, COVID19, COVID19, COVID19
Symptoms: Confusional state, Delirium, Gravitational oedema, Henoch-Schonlein purpura
Clinical narrative: DELIRIOUS; HENOCH-SCHONLEIN PURPURA; DEPENDENT EDEMA; FELT VERY CONFUSED; This spontaneous report received from a patient concerned a 63 year old, white male. The patient's height, and weight were not reported. The patient had no medical history. The patient had no known drug or non-drug allergies and had no drug abuse or illicit use. He was non-alcohol user, and non-smoker. The patient received Covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 1816022 and expiry date: unknown) dose was not reported, 1 total, administered on right arm on 25-AUG-2021 for prophylactic vaccination. No concomitant medications were reported.  On 27-AUG-2021, after 2 days of vaccination, the patient experienced little itchiness on legs and irritation on legs, feet and ankles. He felt very confused and it was not making sense. He had red bright dots dime size all over his legs. His ankles and top of his feet were swollen and hurt so bad that he was not able to walk even for distance of two feet. He felt like a stick man. He developed fever, delusions and sweaty. A few days later, his blood clot like things started to go away then they came back, flourescent bright color all over his legs. His feet hurt so bad, he felt like he gained weight and his leg swollen. He felt like he wanted to get his feet cut off because of the pain. He went to clinic (visited to physician office). The doctor said they looked like blood clots on his legs. The doctor sent him to the emergency room (ER) but he did not go. He waited because he wanted a second opinion so he went to an urgent care. On 06-SEP-2021, the doctor described his condition and he was diagnosed with dependent edema, henoch-schonlein purpura. He received treatment with several medications that included hydrochlorothiazide, buspirone and escitalopram. A day after the spots went away but other symptoms took days for recovery. He felt like his esophagus was swollen, he had difficulty swallowing, his burning and itchy feeling went away. His feet were the last thing to heal. He could not push his foot forward and currently he could. The action taken with Covid-19 vaccine ad26.cov2.s was not applicable. The patient was recovering from henoch-schonlein purpura, and dependent edema, and the outcome of felt very confused and delirious was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: This spontaneous report received from a consumer concerned a 63-year-old Caucasian male who experienced Henoch-Schonlein purpura, dependent edema, and delirium 2 days after vaccination. The patient had no previous illnesses. Concomitant medications were not reported. Two days after vaccination, the patient experienced itchiness and irritation on the legs, ankles, and feet and developed dime size red dots all over his legs. He also experienced painful swelling of ankles and feet, fever and delirium. A physician diagnosed the patient with Henoch-Schonlein purpura and dependent edema.  Treatment includes hydrochlorothiazide, buspirone and escitalopram. At the time of this report, the patient was recovering from Henoch-Schonlein purpura and dependent edema. Information regarding concomitant medications and other potential etiologies was insufficient, and the occurrence of the events could represent the background incidence of such events in the general population. Considering the temporal relationship, the event is assessed to have an indeterminate relationship with vaccination.