Sex: F
Vaccine: TYP
Symptoms: Feeling abnormal, Gait inability, Headache, Heart rate abnormal, Heart rate irregular
Clinical narrative: CHEST PAIN; HER HEART WAS DOING A WEIRD BEAT/ HEARTBEAT WAS ABNORMAL; THE BEATING OF THE HEART FELT OFF; CRAMPING IS SO SEVERE THAT SHE CANNOT WALK; IT IS HARD TO BREATHE/ WHEN SHE INHALES IT MAKES THE PAIN MORE SEVERE; CHILLS; DIZZINESS; NAUSEA; FEVER; HEADACHE; CRAMPING IN THE LIVER AREA AND CHEST PAIN; FELT REALLY ODD; This spontaneous case report (PVX2019-1629) was received from a consumer on 24-Jun-2019. It described a 32-year-old female consumer who reported that she felt really odd  (feeling abnormal), had fever (pyrexia), chills, nausea, dizziness, headache, chest pain, cramping in the liver area and chest pain (abdominal pain), cramping was so severe that she could not walk (gait disturbance), her heart was doing a weird beat/heartbeat was abnormal (heart rate irregular), the beating of the heart felt off (palpitations), and it was hard to breathe/when she inhaled it made the pain more severe(dyspnoea), after the administration of Vivotif capsule for an unknown indication.  Case report: The consumer took Vivotif doses on 17-Jun-2019, 19-Jun-2019, 21-Jun-2019, and 23-Jun-2019, respectively. She reported that the day before the third and the fourth dose, she felt odd. After taking the third dose, she had fever (101.4 degree Fahrenheit), chills, nausea, dizziness, and headache. She stated that she had chest pain and her heart was doing a weird beat as the beating of the heart felt off and her heartbeat was abnormal. She had a severe cramping in the liver area as she felt pain when she walked. She stated that it was hard to breathe. When she inhaled, it made the pain more severe.   The consumer's medical history included Celiac's disease.  She was not on any concomitant and treatment medication.   No action was taken with Vivotif with respect to the events.  The consumer had not resolved from the events chest pain, heart rate irregular, palpitations, abdominal pain, gait disturbance, and dyspnoea while the clinical outcome of the events feeling abnormal, pyrexia, chills, nausea, dizziness, and headache was unknown .  Company's Comment: In this case, it was reported that a female consumer felt really odd, had fever, chills, nausea, dizziness, headache, chest pain, cramping in the liver area and chest pain, cramping was so severe that she could not walk , her heart was doing a weird beat/ heartbeat was abnormal, the beating of the heart felt off, and it was hard to breathe/when she inhaled it made the pain more severe, after the administration of Vivotif. There seems to be a temporal association between the intake of the vaccine and the events. Hence, the causality of the events with Vivotif is assessed as possible.; Sender's Comments: Company's Comment: In this case, it was reported that a female consumer felt really odd, had fever, chills, nausea, dizziness, headache, chest pain, cramping in the liver area and chest pain, cramping was so severe that she could not walk , her heart was doing a weird beat/heartbeat was abnormal, the beating of the heart felt off, and it was hard to breathe/when she inhaled it made the pain more severe, after the administration of Vivotif. There seems to be a temporal association between the intake of the vaccine and the events. Hence, the causality of the events with Vivotif is assessed as possible.