Age: 79.0
Sex: F
Vaccine: COVID19
Symptoms: Chills, Fatigue, Inflammation, Macular degeneration, Pyrexia
Clinical narrative: She experienced macular degeneration; Her vision changed and decreased; She had an inflammatory reaction; From the first dose, she also reports chills, fever, and fatigue; From the first dose, she also reports chills, fever, and fatigue; From the first dose, she also reports chills, fever, and fatigue; This spontaneous case was reported by a nurse and describes the occurrence of MACULAR DEGENERATION (She experienced macular degeneration) in a 79-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 025B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 06-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In 2021, the patient experienced MACULAR DEGENERATION (She experienced macular degeneration) (seriousness criterion medically significant), VISUAL IMPAIRMENT (Her vision changed and decreased), INFLAMMATION (She had an inflammatory reaction), CHILLS (From the first dose, she also reports chills, fever, and fatigue), FATIGUE (From the first dose, she also reports chills, fever, and fatigue) and PYREXIA (From the first dose, she also reports chills, fever, and fatigue). At the time of the report, MACULAR DEGENERATION (She experienced macular degeneration), VISUAL IMPAIRMENT (Her vision changed and decreased), INFLAMMATION (She had an inflammatory reaction), CHILLS (From the first dose, she also reports chills, fever, and fatigue), FATIGUE (From the first dose, she also reports chills, fever, and fatigue) and PYREXIA (From the first dose, she also reports chills, fever, and fatigue) outcome was unknown.        mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) dosing remained unchanged.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medication included ACE inhibitor.  Treatment medication were not provided.  A retired nurse practitioner had called to report that after her Moderna COVID-19 vaccine, she experienced an inflammatory reaction, macular degeneration, her vision changed and decreased. She had an inflammatory reaction from the first dose.  Company Comment: This is a Spontaneous case concerning a 79-year-old female patient, with no medical history reported, who experienced the unexpected and serious event of Macular degeneration. Seriousness assessed due to medically significant event. It occurred on an unknown date after the first dose of mRNA-1273 vaccine. The benefit-risk relationship of mRNA- 1273 vaccine is not affected by this report.   This case was linked to MOD-2022-463239 (Patient Link).; Sender's Comments: This is a Spontaneous case concerning a 79-year-old female patient, with no medical history reported, who experienced the unexpected and serious event of Macular degeneration. Seriousness assessed due to medically significant event. It occurred on an unknown date after the first dose of mRNA-1273 vaccine. The benefit-risk relationship of mRNA- 1273 vaccine is not affected by this report.