Age: 74.0
Sex: M
Vaccine: COVID19
Symptoms: Intracardiac thrombus, Myocardial infarction, Pulmonary thrombosis, SARS-CoV-2 test, Thrombosis
Clinical narrative: Minor heart attack; blood clots in his lung, leg and heart; blood clots in his lung, leg and heart; blood clots in his lung, leg and heart; This spontaneous case was reported by a consumer and describes the occurrence of MYOCARDIAL INFARCTION (Minor heart attack), PULMONARY THROMBOSIS (blood clots in his lung, leg and heart), THROMBOSIS (blood clots in his lung, leg and heart) and INTRACARDIAC THROMBUS (blood clots in his lung, leg and heart) in a 74-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 026A21A and 031M20A) for COVID-19 vaccination.     Concomitant products included LEVOTHYROXINE.   On 13-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 13-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In April 2021, the patient experienced MYOCARDIAL INFARCTION (Minor heart attack) (seriousness criteria hospitalization and medically significant), PULMONARY THROMBOSIS (blood clots in his lung, leg and heart) (seriousness criteria medically significant and life threatening), THROMBOSIS (blood clots in his lung, leg and heart) (seriousness criteria medically significant and life threatening) and INTRACARDIAC THROMBUS (blood clots in his lung, leg and heart) (seriousness criteria medically significant and life threatening). The patient was hospitalized from sometime in April 2021 to sometime in April 2021 due to MYOCARDIAL INFARCTION. The patient was treated with APIXABAN (ELIQUIS) at a dose of 5 mg; CLOPIDOGREL BISULFATE at a dose of 75 mg and AMIODARONE at a dose of 100 mg. In April 2021, MYOCARDIAL INFARCTION (Minor heart attack) had resolved. At the time of the report, PULMONARY THROMBOSIS (blood clots in his lung, leg and heart), THROMBOSIS (blood clots in his lung, leg and heart) and INTRACARDIAC THROMBUS (blood clots in his lung, leg and heart) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, SARS-CoV-2 test: negative (Negative) Negative.         The patient presented to the hospital and was admitted to the Intensive Care Unit (ICU) for a 7 day hospital admission sometime in April 2021 where he was diagnosed and treated for the reported events.  Follow-up blood tests and a sonogram of the patient's leg was performed the week of 06-Jun-2021 through 12-Jun-2021 and a heart sonogram was scheduled on 16-Jun-2021. He was to speak with the doctor about the results on 18-Jun-2021.  This case concerns a 74-year-old male hospitalized with serious unexpected events of myocardial infarction, pulmonary thrombosis, thrombosis, and intracardiac thrombus. Event onset with unknown latency after second dose mRNA-1273. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.; Sender's Comments: This case concerns a 74-year-old male hospitalized with serious unexpected events of myocardial infarction, pulmonary thrombosis, thrombosis, and intracardiac thrombus. Event onset with unknown latency after second dose mRNA-1273. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.