Age: 70.0
Sex: F
Vaccine: COVID19
Symptoms: Ejection fraction, Electrocardiogram, Hyperhidrosis, Magnetic resonance imaging, Myocarditis
Clinical narrative: Acute myocarditis; severe chest pain; shortness of breath; diaphoresis; This literature-study case was reported in a literature article and describes the occurrence of MYOCARDITIS (Acute myocarditis), CHEST PAIN (severe chest pain), DYSPNOEA (shortness of breath) and HYPERHIDROSIS (diaphoresis) in a 70-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.   LITERATURE REFERENCE:  Patients with acute myocarditis following mRNA COVID-19 vaccination.    Concurrent medical conditions included Hypertension, Hypercholesterolemia and Smoker.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced MYOCARDITIS (Acute myocarditis) (seriousness criteria hospitalization prolonged and medically significant), CHEST PAIN (severe chest pain) (seriousness criterion hospitalization prolonged), DYSPNOEA (shortness of breath) (seriousness criterion hospitalization prolonged) and HYPERHIDROSIS (diaphoresis) (seriousness criterion hospitalization prolonged). The patient was hospitalized from sometime in 2021 to sometime in 2021 due to CHEST PAIN, DYSPNOEA, HYPERHIDROSIS and MYOCARDITIS. At the time of the report, MYOCARDITIS (Acute myocarditis), CHEST PAIN (severe chest pain), DYSPNOEA (shortness of breath) and HYPERHIDROSIS (diaphoresis) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Angiogram: normal (normal) normal coronaries, no atherosclerosis. In 2021, Brain natriuretic peptide: abnormal (abnormal) 5194 pg/ml. In 2021, Chest X-ray: normal (normal) normal, No acute pulmonary disease. In 2021, Ejection fraction: abnormal (abnormal) 40 %. In 2021, Electrocardiogram: abnormal (abnormal) anterolateral ST elevation. In 2021, Magnetic resonance imaging: abnormal (abnormal) LGE- present, location- multiple, Myocardial pattern-patchy & diffuse, pericardial enhancement No. Native T1 & T2 in region of LGE abnormal, native T1 & T2 in region without LGE normal. In 2021, Pericardial effusion: small (Low) small. In 2021, Pericardial mass: normal (normal) normal. In 2021, SARS-CoV-2 test: negative (Negative) negative. In 2021, Troponin: abnormal (abnormal) Tn 1:2.34. In 2021, White blood cell count: abnormal (abnormal) 16,700 µL.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered MYOCARDITIS (Acute myocarditis), CHEST PAIN (severe chest pain), DYSPNOEA (shortness of breath) and HYPERHIDROSIS (diaphoresis) to be possibly related.    CRP, ESR, COVID-19 testing, respiratory virus PCR, chest CT was NP (Not performed). Regional wall motion abnormality was present. Concomitant medication not provided. Treatment medication not provided. No prior COVID-19 infection. Additional article received on 08-jul-2021 by safety contains new article with new information.  Very limited information regarding these events has been provided at this time. The events may probably be related to the patient's comorbidities, additional information required.   This case was linked to MOD-2021-249578 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 05-Jul-2021: Report type updated to Literature Study On 07-Jul-2021: Full text article added. Contains new information and new article; Sender's Comments: Very limited information regarding these events has been provided at this time. The events may probably be related to the patient's comorbidities, additional information required.