Age: 43.0
Sex: F
Vaccine: COVID19
Symptoms: Lhermitte's sign, Nerve conduction studies, Nerve injury
Clinical narrative: Nerve damage; Lhemitte's sign symptom/Nerve zingers down trunk and into leg and arm,tilt my head forward, left side but occassionally down both legs; This spontaneous case was reported by a consumer and describes the occurrence of NERVE INJURY (Nerve damage) and LHERMITTE'S SIGN (Lhemitte's sign symptom/Nerve zingers down trunk and into leg and arm,tilt my head forward, left side but occassionally down both legs) in a 43-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 002C21A and 016B21A) for COVID-19 vaccination.     Concurrent medical conditions included Carpal tunnel syndrome since 27-Apr-2021.   On 07-Apr-2021 at 1:30 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 05-May-2021 at 4:15 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 03-Jun-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced LHERMITTE'S SIGN (Lhemitte's sign symptom/Nerve zingers down trunk and into leg and arm,tilt my head forward, left side but occassionally down both legs). On an unknown date, the patient experienced NERVE INJURY (Nerve damage). The patient was treated with PREDNISONE from 28-Jun-2021 to 08-Jul-2021 for Adverse event, at a dose of 1 dosage form; IBUPROFEN (IBUPAR [IBUPROFEN]) for Adverse event, at a dose of 1 dosage form; PARACETAMOL (ACETAMINOFEN) for Adverse event, at a dose of 1 dosage form; MULTIVITAMINS [VITAMINS NOS] for Adverse event, at a dose of 1 dosage form; VITAMIN B12 NOS for Adverse event, at an unspecified dose and frequency; BIOTIN for Adverse event, at an unspecified dose and frequency; Manual therapy (therapeutic massage, hot and cold compresses, acupuncture) for Nerve injury and Manual therapy (Accupunture, hot and cold compresses, therapeutic massage) for Lhermitte's sign. At the time of the report, NERVE INJURY (Nerve damage) outcome was unknown and LHERMITTE'S SIGN (Lhemitte's sign symptom/Nerve zingers down trunk and into leg and arm,tilt my head forward, left side but occassionally down both legs) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 14-Jun-2021, Nerve conduction studies: normal (normal) Normal, no carpel tunnel noted.         No concomitant medications were provided.  An MRI  was conducted on 7-jul-2021, but the results were not reported.   The patient reported receiving therapeutic massage on 13-may-2021  and 01-jul-2021 with no improvement. The patient received acupuncture on 20-may-2021 and 17-jun-2021 with no improvement. The patient also had chiropractor visits on 05-may-2021, 07-may-2021, 10-may-2021, 13-may-2021, 17-may-2021, 20-may-2021, 24-may-2021, 28-may-2021, 03-jun-2021, 07-jun-2021, and 10-jun-2021.   This case was linked to MOD-2021-251617 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 08-Jul-2021: Completed ADR Form appended; Patient demographic details, race and  ethnicity were updated. Lab test and treatment medication were added, new events were added.