Age: 34.0
Sex: M
Vaccine: COVID19
Symptoms: Paraesthesia, Rhinorrhoea, Tension headache, Weight decreased
Clinical narrative: tightness in head; Tightness in his head was so bad, and tingling sensations/ Tightness feeling is like a helmet; numbness; tingling; a loss of appetite; lost weight; Woke up and felt like hell, felt horrible all over again; nausea; fatigue/tired/Felt overwhelmed; flushing in face; temperature felt hot; burning sensation in face and forehead; nose was leaking; This is a spontaneous report received from contactable reporter(s) (Consumer or other non-HCP) from medical information team. The reporter is the patient. Other Case identifier(s): NVSC2021US233682 (Novartis), US-PFIZER INC-202101732289 (PFIZER).  A 34-year-old male patient received bnt162b2 (BNT162B2), administered in arm left, administration date 15Sep2021 20:30 (Batch/Lot number: unknown) at the age of 34 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Multiple sclerosis", start date: 2000 (ongoing), notes: 2000. Concomitant medication(s) included: GILENYA taken for multiple sclerosis, start date: 2008 (ongoing). The following information was reported: TENSION HEADACHE (non-serious), outcome "unknown", described as "tightness in head"; FEELING ABNORMAL (non-serious) with onset 19Sep2021, outcome "not recovered", described as "Tightness in his head was so bad, and tingling sensations/ Tightness feeling is like a helmet"; FATIGUE (non-serious) with onset 16Sep2021, outcome "recovered" (16Sep2021), described as "fatigue/tired/Felt overwhelmed"; NAUSEA (non-serious) with onset 17Sep2021, outcome "recovered" (17Sep2021), described as "nausea"; HYPOAESTHESIA (non-serious) with onset 19Sep2021, outcome "unknown", described as "numbness"; PARAESTHESIA (non-serious) with onset 19Sep2021, outcome "not recovered", described as "tingling"; DECREASED APPETITE (non-serious) with onset 19Sep2021, outcome "not recovered", described as "a loss of appetite"; WEIGHT DECREASED (non-serious) with onset 19Sep2021, outcome "not recovered", described as "lost weight"; RHINORRHOEA (non-serious) with onset 2021, outcome "unknown", described as "nose was leaking"; FEELING ABNORMAL (non-serious) with onset 19Sep2021, outcome "unknown", described as "Woke up and felt like hell, felt horrible all over again"; FLUSHING (non-serious) with onset 2021, outcome "not recovered", described as "flushing in face"; FEELING HOT (non-serious) with onset 2021, outcome "not recovered", described as "temperature felt hot"; BURNING SENSATION (non-serious) with onset 2021, outcome "not recovered", described as "burning sensation in face and forehead". The event "tightness in head" was evaluated at the physician office visit. The events "tightness in his head was so bad, and tingling sensations/ tightness feeling is like a helmet", "fatigue/tired/felt overwhelmed", "nausea", "numbness", "tingling", "a loss of appetite", "lost weight" and "nose was leaking" were evaluated at the physician office visit and emergency room visit. Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Patient stated that since he had the COVID vaccine he had been experiencing a tightness in his head, MS symptoms have worsened, had headaches and was tired. He is reporting symptoms of having tightness in head like wearing helmet. He noted that this is not a headache. He had consulted his neurologist and had an MRI scan where they found there was no difference with the MRI scan, he had earlier this year. take that vaccine difference back side of my face comes and goes but mostly there. He is asking if there has been any reports or information on side effects for people with Multiple Sclerosis. Caller states he is wondering if there is any insight on the situation he has been having for the past month or so.  States that he took his first dose of the vaccine on 15 Sep 2021.  At that time, he talked to the people at the pharmacy, and they said the most common thing was having fatigue the next day after the vaccine. he takes Gilenya for relapsing/remitting MS.  Says that he started it on a clinical trial in 2008 and continued taking it since then; states it was FDA approved in 2010. Reported that lot no was either FD8448 or F08448 or FO8448. he was not admitted into the hospital when he went to the emergency room.  He was given the option to be observed overnight, but he declined.  States they gave him some saline to hydrate him and then he went home. He is calling back because he received 1st dose on 15Sep2021, and ever since then, he started experiencing flushing in face, and his temperature felt hot.  It is hard to wear mask and hats because he has a burning sensation in face and forehead.  It has not gone away.  He would like to mention he is an MS patient.  Everything is negative.  So that with him going to office visits and getting his temperature taken, he confirmed that he is not having a temperature. States that this past Friday his doctor also did blood work, but those results haven't been received by the doctor yet. States he had taken a cooler shower and when he got out, he Felt so overwhelmed he went to the emergency room, they gave him saline to hydrate him.  States they did blood work at that time and talked to a MS specialist.  They told him his blood work was normal and okay. Caller states that about 2 Sunday's ago he was feeling bad enough that he went to the emergency room. Caller states that his doctor prescribed him to get the Covid Vaccine in February but that he was hesitant due to being immunocompromised with MS.  States he works from home and rarely leaves the house, except for maybe a couple times on the weekends. Caller states that he took Sudafed for about 7 days in a row to see if maybe it was allergies and Sudafed would help.  States that for 2 days in a row his nose was leaking, and he thought it was working and he felt kind of better.  At that time, he thought it was just allergies.  He was told that his MRI shows it is not allergies. Caller says that the tightness feeling is persistent, it comes and goes.  States that it is treacherous.  He will wake up every day feeling like he is okay; then he will suddenly get this feeling in his head and know that it is still there. Caller states that he would say his nausea and fatigue only lasted for the 2 days that they began on.  Fatigue on 16Sep2021 and nausea on 17Sep2021. Caller states that with MS if you strain your body, you will get a numb feeling.  States he doesn't know if it was his MS or stress on his body, it felt like head pressure. The numbness came back the next morning when he got up. Caller states that his neurologist didn't have concerns and suggested an MRI.  Caller states that the MRI was on 01Oct2021, and the results were no different than the MRI he had earlier this year.  Follow-up attempts completed. No further information is expected