Age: 65.0
Sex: F
Vaccine: COVID19
Symptoms: Knee arthroplasty, Liver function test
Clinical narrative: she got diverticulitis and went to the ER/ patient was in hospital for diverticulitis flare up; they kept me overnight and found cirrhosis of the liver; States they had to keep her because potassium started falling and magnesium started falling so they had to get those up and then let her go home; States they had to keep her because potassium started falling and magnesium started falling so they had to get those up and then let her go home; knee replacement surgery; flare up in Jun2021; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 65-year-old female patient received BNT162b2 (BNT162B2), on 23Mar2021 as dose 2, single (Lot number: EN6203) at the age of 65 years for covid-19 immunisation. The patient's relevant medical history included: "Diverticulitis" (unspecified if ongoing), notes: Diverticulitis diagnosed three years before the event; "knee issues" (unspecified if ongoing), notes: had knee issues prior to vaccines. There were no concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Lot: EN6201), administration date: 03Mar2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "didn't feel good", "States she thinks she got the first shot in her right arm because she remembered it made her arm hurt", "Sore". The following information was reported: KNEE ARTHROPLASTY (medically significant) with onset 02Jun2021, outcome "unknown", described as "knee replacement surgery"; ARTHRITIS (non-serious) with onset Jun2021, outcome "unknown", described as "flare up in Jun2021"; HEPATIC CIRRHOSIS (hospitalization, medically significant) with onset Jun2022, outcome "not recovered", described as "they kept me overnight and found cirrhosis of the liver"; DIVERTICULITIS (hospitalization, medically significant, life threatening), outcome "unknown", described as "she got diverticulitis and went to the ER/ patient was in hospital for diverticulitis flare up"; BLOOD POTASSIUM DECREASED (non-serious), BLOOD MAGNESIUM DECREASED (non-serious), outcome "unknown" and all described as "States they had to keep her because potassium started falling and magnesium started falling so they had to get those up and then let her go home". The patient was hospitalized for diverticulitis, hepatic cirrhosis (start date: Jun2021, discharge date: Jul2021). The patient underwent the following laboratory tests and procedures: Blood glucose: (unspecified date) 145, notes: blood glucose was 145; Blood magnesium: (unspecified date) falling; Blood potassium: (unspecified date) falling; Computerised tomogram abdomen: (Jun2021) Unknown result, notes: CT scan, abdomen/pelvis with contrast was in Jun2021, showed cirrhosis; Computerised tomogram pelvis: (Jun2021) Unknown result, notes: CT scan, abdomen/pelvis with contrast was in Jun2021, showed cirrhosis; Liver function test: (Jun2021) fine.  Clinical course: She states that she had her knee operated on 02Jun2022 and several days later she got diverticulitis and went to the ER. She states that she had symptoms and "they kept me overnight and found cirrhosis of the liver. She was asking "does the Pfizer Covid19 vaccine have any correlation with cirrhosis of the liver? She states she was just sitting here thinking this morning, doesn't drink very much at all, last time she had a drink was three weeks ago this Thursday, states that all of a sudden, she showed up with cirrhosis of the liver when she went in to get diverticulitis scans. Did not realize it was life threatening. Never had any issues with her liver until after she got the Pfizer Covid vaccines. She states she had a liver test way back in 96 and was tested after her friend died of hepatitis C and since she took care of her, she got tested because they were in close contact, but she was fine. Was diagnosed with cirrhosis in Jun2021. Did not think that it was a big deal because the doctors acted like it wasn't. States she originally went in for diverticulitis flare and they did a CT with contrast, and it showed the cirrhosis. Doctor ordered all the blood work and told her it looked fine. It scared her because her hairdresser's daughter died of cirrhosis. Had surgery 02Jun2021 for a right knee replacement, had knee issues prior to vaccines, went home from surgery and started having gastrointestinal symptoms went into the hospital on 16 Jun2021 with a full-blown diverticulitis flare up and got sent home, went back into the hospital at the end of the week and they admitted her and that was when they did the CT scan with contrast and found the cirrhosis of the liver. States they had to keep her because potassium started falling and magnesium started falling so, they had to get those up and then let her go home. Exact Dates of hospitalization unknown, states from end of Jun2021, around 28Jun2021 to the beginning of Jul2021. She clarifies that the cirrhosis of the liver diagnosed in Jun2021 was after she received the first two Covid vaccines, and clarifies she was diagnosed with diverticulitis about 3 years prior to the vaccines, however she had a flare up in Jun2021after she had knee replacement surgery on 02Jun2021, states the knee issues were also diagnosed prior to any Covid vaccines. Also noticed that after she got the shot, she could close her eyes and look around and it looked like things were crawling around, like little bugs like looking in a microscope, exact dates unknown.