Sex: F
Vaccine: HPV4, HPV9
Symptoms: Weight decreased
Clinical narrative: She was found to have contracted HPV; Losing 1 to 2 pounds in the last several years; She is sad, confused and shocked; She is sad, confused and shocked; She is sad, confused and shocked; Cervical Cancer stage 0 / PAP smear-irregularities; I got HPV 18 despite getting the GARDAIL and GARDASIL9 / The vaccine she received did not protect her from contracting the strain of HPV.; Diagnosed with HPV 18; Received 1 dose of GARDASIL and then received the "Improved version of GARDASIL" which was GARDASIL9; This spontaneous report was received from an approximately 18-year-old non-pregnant female patient regarding herself.  The patient was not sexually active, no information was provided regarding the patient's medical history, drug reactions, allergies or concomitant medications.  On an unknown date, when the patient was a child, the patient was vaccinated with Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported).  On an unspecified date in 2012,  reported as  2012 or 2013, she was starting school , the patient was vaccinated with HPV rL1 6 11 16 18 31 33 45 52 58 VLP vaccine (yeast) (GARDASIL 9) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported). The vaccine was administered by her mother that was a Obstetrician and Gynecologyst.   Since an unknown date, reported as "in the last several years", the patient had been losing 1 to 2 pounds (weight decreased).   On an unknown date, reported as about couple years ago, irregularities were found on her papanicolaou (PAP) smear and she was found to have contracted human papilloma virus (HPV) (HPV infection) exact strain unknown at the time.  On an unspecified date in 2020, the patient her PAP came back with irregularities again. On 03-SEP-2020, she had a loop electrosurgical excision procedure (LEEP) and was diagnosed with HPV 18. On 20-OCT-2020, she received colposcopy of cervix and diagnosed with stage 0 cervical cancer (cervix carcinoma stage 0). On 29-JAN-2021, the pre-cancerous cells were removed.   The patient stated that the vaccines that she received did not protect her from contracting the strain of HPV she should have been protected from, she got HPV 18 despite getting the vaccines (vaccination failure). Since an unknown date, the patient was sad (depressed mood), confused (confusional state) and shocked (also reported as disturbed) (feeling abnormal) because she somehow managed to get the HPV strain despite getting the vaccine.  The outcome of the events weight decreased, depressed mood, confusional state and feeling abnormal was reported as not resolved and for the remaining events was not reported. The causal relationship between the event vaccination failure and vaccination with quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) and HPV rL1 6 11 16 18 31 33 45 52 58 VLP vaccine (yeast) (GARDASIL 9) was assessed as related but for the remaining events the causal relationship was unknown.  Upon internal review, the event cervix carcinoma stage 0 was considered to be medically significant.