Age: 1.0
Sex: U
Vaccine: MMR, VARCEL
Symptoms: Rash, Rash morbilliform, Rhinorrhoea
Clinical narrative: Information has been received from a physician concerning an approximately 12 month old patient who on approximately 1/17/03 was vaccinated with a dose of MMR (second generation) (lot # not reported). Concomitant therapy included varicella virus vaccine live. On approximately 1/26/03 the patient developed a rash and runny nose. A few days later, the patient developed conjunctivitis, dry mucus membranes, lethargy, and it was noted that the rash was expanding. The patient was admitted to the hospital and the patient is suspected to have the measles. As of 1/31/03 the patient remains hospitalized. Additional information has been requested.  Reported on 04/04/2003: "On 01/15/2003 the patient was vaccinated with a dose of measles virus vaccine live (+) mumps virus vaccine live (+) rubella virus vaccine live (second generation)(Lot # 643497/0770M).  Additional therapy also included vaccination on 01/15/2003 with a dose of varicella virus vaccine live (Lot #643121/0548M).  On follow up it was reported by the nurse that the patient was seen in the office on 01/19/2003 with cold-like symptoms, nasal congestion, poor food intake and vimiting.  On 01/22/2003 the cold-like symptoms had moved into the child's chest.  Initial report by the physician had also noted a runny nose.  The nurse reported that on 01/25/2003 the child was seen in the physician's office for a rash and an upper respiratory infection.  Initial information reported by the physician had noted that on aproxinately 02/29/2003 that the child had developed a rash that was expanding, dry mucus membranes, lethargy, conjunctivitis and the child was admitted to the hospital and was suspected to have the measles.  Follow up information reported by the nurse indicated that on 01/28/2003 the child developed lethargy and was seen by "infectious disease" at the hospital.  The child was admitted to the on hospital on 01/28/2003 and was diagnosed with viral encephalitis.  The nurse reported that she did not think that the child was treated with any specific medication and she reported that treatment might possibly have been intravenous fluids and observation.  On 02/02/2003 the child was discharged from the hospital.  The nurse reported that on 02/08/2003 the child's mother called the physician office and reported that the rash was better but not completely gone, as a pinpoint rash was still present.  The mother also reported that her daughter's lethargy was better, but that she was not back to normal yet.  the nurse also reported that on 02/18/2003 the child was seen in the physician's office with a cough, clear runny nose and poor appetite.  Upon examination an inspiratory stridor with crying was noted.  A questionable diagnosis of early croup was noted.  The nurse reported that the child was stil recovering from the viral encephalitis.  Additional information has been requested.  On follow up, the nurse reported that the patient's sibling had an adverse event of otitis media following vaccination with measles virus vaccine live (+) mumps virus vaccine live (+) rubella virus vaccine live (second generation) and varicella virus vaccine live (WAES# 0303USA02028).