Age: 57.0
Sex: F
Vaccine: COVID19
Symptoms: Injection site mass, Injection site pain, Mammogram, Pain assessment, Ultrasound scan
Clinical narrative: LUMP AT INJECTION SITE; LEFT SHOULDER PAIN AT INJECTION SITE; MARGINAL B CELL LYMPHOMA; This spontaneous report received from a patient concerned a 57 year old female of unspecified race and ethnic origin. The patient's height, and weight were not reported. No past medical history or concurrent conditions were reported. The patient received covid-19 vaccine ad26.cov2.s (dose number in series 1) (suspension for injection, route of admin not reported, batch number: 1855194, expiry: UNKNOWN) dose was not reported, 1 in total administered to left deltoid on 04-AUG-2021 for prophylactic vaccination. No concomitant medications were reported. Around early to mid August 2021, following vaccination with covid-19 vaccine ad26.cov2.s, the patient felt a pain in the right flank (towards the right hip). The patient visited a dermatologist around 10-Aug-2021 for the pain, who sent her for testing. On 19-Aug-2021, she received an ultrasound and showed 09 into 08 cm heterogenous mass just below the skin surface along the right flank. On 23-Sep-2021, Computed tomography (CT scan) of chest and abdomen was done for the initial complaint of the heterogenous mass on the right hip which had not shown that it was an unremarkable study. On 28-Sep-2021, patient also had a routine mammogram which came back fine. Around 15-Nov-2021, the patient also developed 2 masses on the right side flank (described as where a woman's bra strap would) and back side of the left shoulder. She described the masses as very dark in color, raised, and noticeable. The one the shoulder was smaller than a quarter and the 2 on the flank were larger than a quarter but felt bigger than it looked. Since the CT above was unremarkable, she made an appointment with her primary dermatologist to assess the right hip mass once more, but by this time she had developed the masses described above as being on the right flank and left shoulder so the dermatologist focused on those masses. She had a biopsy of the masses on the right flank and the left shoulder on 29-Nov-2021 by the primary dermatologist, which showed an atypical lymphoid infiltrate. The patient was diagnosed with marginal B-cell Lymphoma on 23-Dec-2021. On an unspecified date the patient had left shoulder pain at the injection site and a lump at the injection site that was still there, the pain was described as a 1/10 but noticeable (dose number in series 1). The patient also visited Cancer Centre on 18-JAN-2022 where she had another biopsy (of the right flank only) and blood work done. The biopsy results were pending, and the blood work came back normal with a couple of red flags. The action taken with covid-19 vaccine ad26.cov2.s was not reported. The patient had not recovered from marginal b cell lymphoma, left shoulder pain at injection site, and lump at injection site. This report was serious (Other Medically Important Condition). This case, involving the same patient is linked to 20220146890 (dose number in series 2).; Sender's Comments: V0: 20220145846- COVID-19 VACCINE AD26.COV2.S- MARGINAL B CELL LYMPHOMA. This event(s) is considered not related. The event(s) shows an incompatible temporal relationship.