Sex: F
Vaccine: COVID19
Symptoms: Eye disorder, Fat tissue decreased, General physical condition abnormal, Lipoatrophy, Myocardial infarction
Clinical narrative: KINDA HAD A HEART ATTACH OR SOMETHING LIKE THAT; STENOSIS; SCREWED UP TENDONS; I HAVE SOME PHYSICAL PROBLEMS; I HAD A RASH ONCE IT WENT AWAY; MY EYES SUCK; LIPID ATROPHY; LOOSING FAT; This spontaneous report received from a patient concerned a female of unspecified age. The patient's height, and weight were not reported. The patient's concurrent conditions included: HIV. The patient received darunavir/cobicistat/emtricitabine/tenofovir alafenamide (film-coated tablet, oral, batch number: 22AG226 expiry: 31-AUG-2024) dose and frequency were not reported from 2018 for hiv. The patient received covid-19 vaccine ad26.cov2.s (dose series 1) (suspension for injection, intramuscular, batch number was not reported) dose, start therapy date were not reported for covid-19 prophylaxis. Non-company suspect drugs included: hyaluronic acid (form of admin, route of admin, and batch number were not reported) dose, frequency, and therapy dates were not reported for an unspecified indication. ; and hyaluronic acid (form of admin, route of admin, and batch number were not reported) dose, frequency, and therapy dates were not reported for an unspecified indication.  Batch number was not provided and have been requested. No concomitant medications were reported.  It was reported that inbound call from consumer who states that she takes symtuza for the treatment of hiv. She reported that she started taking it "around 2018" and that she has had hiv "from 1979 until now." Consumer stated that she was calling to find out if the product interacts with hyaluronic acid or restylane fillers and if it causes facial wasting. consumer reported that she has had hyaluronic acid or restylane fillers that, "dissipate a few weeks after they are put in." Caller said that she has "lipid atrophy" (dose in series 1), loosing fat (dose in series 1) in her "arms face and legs." Caller continued by talking about her health history and stated that the, "covid thing happened" but when asked did not clarify if she actually had covid. she stated, "she did the j and j first" as she was referring to covid vaccine. She also stated that she spent a lot of money on facial fillers because, "She wont leave the house looking like this." she also said, "the minute they put it in it disappeared." caller continued by saying, " she had some physical problems (dose series 1) " and that she use to be a body builder and she has "stenosis (dose series 1) and that screwed up tendons (dose series 1)." She went on to say, " she kinda had a heart attach or something like that (dose series 1)." "She have been on and off drugs since the 80's". Patient had a rash (dose series 1) once it went away." She went on to say that she got a treadmill, "so she can walk again...which she can't do now because she don't have the strength" she went on to say, "the doctor has me on growth hormone. She was finally gaining the weight back" when asked the caller if she could provide expiration date, lot, gtin, ndc and serial numbers she stated, "my eyes suck (dose series 1)." she did provide numbers that are in this form. She provided part of the ndc number, but stated that there was a label placed over it. when speaking about taking her medication she said, "they make me feel like crap" "they're horrible (dose series 1) " when asked about the dosage of her symtuza she stated, -"she adjusted the dose" "she have been been taking half of a pill a day and it works just fine." The action taken with covid-19 vaccine ad26.cov2.s was not applicable; action taken with darunavir/cobicistat/emtricitabine/tenofovir alafenamide, hyaluronic acid, and hyaluronic acid was not reported; and dose of darunavir/cobicistat/emtricitabine/tenofovir alafenamide was decreased. The patient recovered from i had a rash once it went away, and the outcome of stenosis, screwed up tendons, i have some physical problems, kinda had a heart attach or something like that, my eyes suck, lipid atrophy and loosing fat was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0;  Myocardial infarction; The event has an unknown/unclear temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event. Therefore, the WHO Causality is considered indeterminate. The company causality is considered unassessable.