Sex: F
Vaccine: COVID19, COVID19, PPV, VARZOS
Symptoms: Vaccination site pain, Vaccination site swelling
Clinical narrative: She was knocked out for a long time; With high blood pressure medication, she can't take a decongestant because it raises blood pressure; With high blood pressure medication, she can't take a decongestant because it raises blood pressure; The second shingles shot that they gave her, the one that is 60-70 days apart was God-awful; She didn't have feel good/really didn't feel good; Her arm was sore; With the third pneumococcal shot, she did have trouble with it. Her arm swelled up; she felt lousy/ that was the only one she felt God-awful with; This spontaneous report has been received from a consumer referring to herself a female patient, who currently was 80-years-old.  The patient's concurrent conditions included macular degeneration and postmenopausal osteoporosis. Her patient's concomitant therapies, and historical conditions were not reported.  On unknown date, the patient started therapy with lisinopril (manufacturer unknown) 10 milligrams (mg) once daily in the morning orally (she took it slowly when she got up and got out of bed) for blood pressure high (lot number and expiry date were not provided). On an unspecified date in 2020, the patient was vaccinated with the third dose of pneumococcal vaccine, polyvalent (23-valent) (manufacturer unknown), and on an unspecified date she was vaccinated with the second dose of zoster vaccine live (manufacturer unknown); both as prophylaxis (dose, route of administration, vaccination scheme frequency, anatomical location, lot number and expiry date were not provided. She received all the vaccines at a facility (unspecified).  On an unknown date in 2020, the patient reported that her arm swelled up (vaccination site swelling), and she felt lousy (feeling abnormal). That was the only vaccine she felt "really god-awful" with, after vaccination with the third dose of pneumococcal vaccine, polyvalent (23-valent) (manufacturer unknown). On an unspecified date, it was stated that with high blood pressure medication, the patient could not take a decongestant because it raised her blood pressure (blood pressure increased) (drug interaction). Also, after she received the second dose of zoster vaccine live (manufacturer unknown), she reported that she was "god-awful" (feeling abnormal), her arm was sore (vaccination site pain), she did not feel good (malaise), and she was knocked out for a long time (loss of consciousness); nevertheless, she was functioning (conflicting information as it was also reported she did not have a physical reaction).The outcome for all the events was unknown.  The action taken regarding lisinopril (manufacturer unknown) with loss of consciousness, blood pressure increased ,feeling abnormal, malaise, vaccination site swelling, vaccination site pain and drug interaction was not reported.  The causal relationship between all the events, pneumococcal vaccine, polyvalent (23-valent) (manufacturer unknown) and zoster vaccine live (manufacturer unknown), and the causal relationship between the events loss of consciousness, feeling abnormal, malaise, vaccination site swelling, vaccination site pain, and lisinopril (manufacturer unknown) were not provided. The causal relationship with blood pressure increased, drug interaction and lisinopril (manufacturer unknown) was considered as related. Upon internal review, the event loss of consciousness was determined to be medically significant.