Age: 75.0
Sex: M
Vaccine: COVID19
Symptoms: Constipation, Diarrhoea, Feeling abnormal, Flatulence
Clinical narrative: developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.; developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas/unexpected and very sudden loose bowel movements/intermittent diarrhea; Caller states He felt "Like crap" the following day after the vaccine; developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.; This spontaneous case was reported by a patient and describes the occurrence of CONSTIPATION (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.), FLATULENCE (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.), FEELING ABNORMAL (Caller states He felt "Like crap" the following day after the vaccine) and DIARRHOEA (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas/unexpected and very sudden loose bowel movements/intermittent diarrhea) in a 75-year-old male patient who received mRNA-1273.815 (SPIKEVAX 2023-2024) for COVID-19 prophylaxis.     Previously administered products included for COVID-19 prophylaxis: MODERNA COVID-19 VACCINE (dose 1), MODERNA COVID-19 VACCINE (dose 4), MODERNA COVID-19 VACCINE (dose 3) and MODERNA COVID-19 VACCINE (dose 2). Past adverse reactions to the above products included No adverse event with MODERNA COVID-19 VACCINE, MODERNA COVID-19 VACCINE, MODERNA COVID-19 VACCINE and MODERNA COVID-19 VACCINE.    On 12-Feb-2024, the patient received fifth dose of mRNA-1273.815 (SPIKEVAX 2023-2024) (unknown route) 1 dosage form. On 13-Feb-2024,  after starting mRNA-1273.815 (SPIKEVAX 2023-2024), the patient experienced FEELING ABNORMAL (Caller states He felt "Like crap" the following day after the vaccine). On 15-Feb-2024, the patient experienced FLATULENCE (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.) and DIARRHOEA (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas/unexpected and very sudden loose bowel movements/intermittent diarrhea). In February 2024, the patient experienced CONSTIPATION (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.). On 14-Feb-2024, FEELING ABNORMAL (Caller states He felt "Like crap" the following day after the vaccine) had resolved. At the time of the report, CONSTIPATION (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.), FLATULENCE (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas.) and DIARRHOEA (developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas/unexpected and very sudden loose bowel movements/intermittent diarrhea) had not resolved.        For mRNA-1273.815 (SPIKEVAX 2023-2024) (Unknown), the reporter did not provide any causality assessments.   The patient did not receive any other vaccines in the 4 weeks prior to COVID-19 vaccine. No concomitant medication was reported. The patient received Spikevax on 12FEB2024 and has since developed chronic constipation with occasional bouts of unexpected diarrhea with associated bloating and "large amount of gas." This condition did not begin until after the vaccination. The patient felt "Like crap" the following day after the vaccine, then felt totally normal on day 2 after vaccine. On day 3 after the vaccine, the patient started having unexpected and very sudden loose bowel movements. The bouts were so sudden that he had to change his underwear several times throughout the day. After a few days of intermittent diarrhea, constipation began and has persisted with intermittent bouts of anal leakage/sudden diarrhea. The patient had seen a gastroenterologist who took urine, blood and stool samples as well as an X-ray, results not available at the time of this call. No treatment medication was reported.