Age: 27.0
Sex: M
Vaccine: FLUX
Symptoms: Nasopharyngitis, Nausea, Pericardial rub, Pericarditis, Red blood cell sedimentation rate increased
Clinical narrative: Myopericarditis; Chest pain; Diaphoresis; Nausea; Emesis; Elevated troponin level; Mild cold symptoms; Pericardial rub; ST elevations; PR depressions; Elevated erythrocyte sedimentation rate; Elevated c-reactive protein (CRP); This literature case was received on 02-Apr-2024 from other healthcare professional, and concerned a 27-year-old male patient.   The aim of this conference abstarct was to describe a case of myopericarditis in a young, previously healthy individual following influenza vaccination.  The patient's medical history and concomitant medications were not reported. The patient denied any history of chest pain in the past and endorsed an active lifestyle (previously healthy individual).  On an unspecified date, the patient was vaccinated with influenza vaccine (brand not specified; dose, anatomical location, route of administration and indication: not reported). The batch number was not reported.   On an unspecified date, a few days after receiving influenza vaccine, the patient experienced mild cold symptoms.   On an unspecified date, the patient presented to the emergency room with chest pain accompanied by diaphoresis, nausea, and emesis. In the emergency department, the patient was found to have an elevated troponin level. The patient was loaded with aspirin, started on a heparin drip, and transferred to the authors' facility for possible catheterization for suspected non-ST-elevation myocardial infarction.   On an unspecified date, an exam revealed a pericardial rub. Electrocardiogram was suspicious for pericarditis with diffuse ST elevations and PR depressions. Labs showed elevated erythrocyte sedimentation rate and C-Reactive Protein (CRP).   On an unspecified date, given the patient's young age, no family history of early cardiac disease, and high suspicion for pericarditis, the patient was started on colchicine and high dose aspirin.  On an unspecified date, the patient underwent a cardiac magnetic resonance imaging which revealed findings consistent with myocarditis.   At the time of the initial reporting, the patient was recovering from the event of myopericarditis. As reported, the patient's symptoms improved over the following two days with a decrease in CRP.  The reporter assessed the event of myopericarditis as possibly related to influenza vaccine.   In conclusion, this case highlights a rare but serious possible complication of influenza vaccination. While there are reports of pericarditis and myocarditis after influenza vaccination, the true incidence is not well documented. While influenza vaccination is generally considered safe, it is important to consider vaccination history young patients presenting with chest pain to provide timely diagnosis and proper management.; Reporter's Comments: Listedness: Unlisted. Causality: Considering close proximity of onset of first symptoms, and taking into account the laboratory findings provided causal role of the suspect vaccine could not be ruled out. Additionally applied treatment with subsequent improvement speaks in support of an autoimmune rather then infective aetiology. With the curently available information causality for the event myopericarditis is assessed as possibly related.