Age: 63.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Radiotherapy, SARS-CoV-2 test positive
Clinical narrative: Received Janssen vaccine on 4/2/21. Tested positive for COVID by PCR on 11/9/21 Previously COVID positive by PCR on 5/19/21, 8/6/21, 9/8/21, 10/14/21 Underlying cervical cancer Admitted to Hospital on 11/11/21-12/16/21, expired on 12/16/21 due to metastatic malignant neoplasm (cervical and squamous cell right lung). Per Hospital Dismissal summary: On 11/10/21, she presented to the emergency room with several days of weakness, myalgias, shortness of breath, and nausea as well as worsening leukocytosis in the setting of known COVID-19 infection.  A CT angio was obtained and negative for pulmonary embolism but showed an increasing right-sided pleural effusion with right upper lobe consolidation.  She was admitted to Hospital for further cares.   Her symptoms were felt to be mainly secondary to her underlying malignancy rather than COVID 19. Oncology was consulted and reviewed pathology and determined that her multiple lesions (lung, liver, adrenals, and lymphatics) were secondary to metastatic cervical CA. Pulmonary Medicine was consulted for pleural effusions. Patient's case was discussed at tumor board and plan was formulated to proceed with grid therapy on 12/8/2021 with the goal to complete a total of 6 fractions of palliative radiation by 12/13/2021.  Unfortunately, her treatment on 12/08/2021 was complicated by acute hemoptysis and oxygen desaturation prompting RRT.  She was stabilized and returned to hospital medicine floor without treatment. Medical Oncology determined that given patient's clinical status, the risks outweighed the benefits of further treatment and signed off. Radiation Oncology determined that patient was too unstable to receive any benefit from further radiation and also signed off.On 11/10/21, she presented to the emergency room with several days of weakness, myalgias, shortness of breath, and nausea as well as worsening leukocytosis in the setting of known COVID-19 infection.  A CT angio was obtained and negative for pulmonary embolism but showed an increasing right-sided pleural effusion with right upper lobe consolidation.  She was admitted to Hospital for further cares. Her symptoms were felt to be mainly secondary to her underlying malignancy rather than COVID 19. Oncology was consulted and reviewed pathology and determined that her multiple lesions (lung, liver, adrenals, and lymphatics) were secondary to metastatic cervical CA. Pulmonary Medicine was consulted for pleural effusions. Patient's case was discussed at tumor board and plan was formulated to proceed with grid therapy on 12/8/2021 with the goal to complete a total of 6 fractions of palliative radiation by 12/13/2021.  Unfortunately, her treatment on 12/08/2021 was complicated by acute hemoptysis and oxygen desaturation prompting RRT.  She was stabilized and returned to hospital medicine floor without treatment. Medical Oncology determined that given patient's clinical status, the risks outweighed the benefits of further treatment and signed off. Radiation Oncology determined that patient was too unstable to receive any benefit from further radiation and also signed off.  PREVIOUSLY REPORTED VAERS HOSPITALIZATION, reference #726390