Age: 73.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Bone pain, Complications of transplant surgery, Headache, Myalgia
Clinical narrative: sepsis; complications during knee replacement; aching all over her legs aching in the middle,whole legs aching; bones pain; aching in the joints, aching in the ankles,aching in the elbows and hip, the joints kill her, her artificial knee it's aching as well; aching all over,the muscles kill her; headaches off and on; This spontaneous case was reported by a consumer and describes the occurrence of SEPSIS (sepsis) and COMPLICATIONS OF TRANSPLANT SURGERY (complications during knee replacement) in a 74-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 027L20A and 039K20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was reported.  The patient's past medical history included Knee replacement in March 2021. Concomitant products included ATENOLOL, LISINOPRIL, METFORMIN, MONTELUKAST SODIUM (SINGULAIR), ALPRAZOLAM (XANAX), ACETYLSALICYLIC ACID (BABY ASPIRIN), DULOXETINE and VITAMIN D NOS for an unknown indication.   On 25-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 22-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced SEPSIS (sepsis) (seriousness criterion medically significant), COMPLICATIONS OF TRANSPLANT SURGERY (complications during knee replacement) (seriousness criterion medically significant), PAIN IN EXTREMITY (aching all over her legs aching in the middle,whole legs aching), BONE PAIN (bones pain), ARTHRALGIA (aching in the joints, aching in the ankles,aching in the elbows and hip, the joints kill her, her artificial knee it's aching as well), MYALGIA (aching all over,the muscles kill her) and HEADACHE (headaches off and on). The patient was treated with PARACETAMOL (TYLENOL) for Ache and Headache, at an unspecified dose and frequency. At the time of the report, SEPSIS (sepsis), COMPLICATIONS OF TRANSPLANT SURGERY (complications during knee replacement), PAIN IN EXTREMITY (aching all over her legs aching in the middle,whole legs aching), BONE PAIN (bones pain), ARTHRALGIA (aching in the joints, aching in the ankles,aching in the elbows and hip, the joints kill her, her artificial knee it's aching as well), MYALGIA (aching all over,the muscles kill her) and HEADACHE (headaches off and on) outcome was unknown.            Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  Case may be confounded by recent knee surgery. Further information is expected.   This case was linked to MOD-2021-276513 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.  Case may be confounded by recent knee surgery. Further information is expected.