Age: 6.0
Sex: F
Vaccine: IPV
Symptoms: Exposure via skin contact, Pyrexia, Seizure, Syringe issue
Clinical narrative: sustained a minute long seizure; temperature of 101.5 Fahrenheit; during the injection the liquid squirted out of the syringe where the needle was attached all over the patients arm and floor; during the injection the liquid squirted out of the syringe where the needle was attached all over the patients arm and floor; Initial information regarding an unsolicited valid serious case was received from other health care professional via Medical Information (Reference number- 00711792) and transmitted to Sanofi on 05-Aug-2021.  This case involves a six-year-old female patient who had sustained a minute long seizure (seizure), temperature of 101.5 Fahrenheit (pyrexia) after receiving IPV (VERO) [IPOL].  The patient's medical history, past medical treatment(s), vaccination(s) and family history were not provided.  Concomitant medications included VARICELLA ZOSTER VACCINE (VARICELLA VACCINE) received on 04-Aug-2021 for prophylactic vaccination.  On 04-Aug-2021, the patient received a dose three (0.5 mL) of suspect IPV (VERO) (lot T1D481M, expiry date: 25-Jul-2022) via an intramuscular route in the right deltoid for prophylactic vaccination.  It was also the case of exposure via skin contact and syringe leak (syringe issue) on 04-Aug-2021 (latency: same day).  The reporter stated that a dose of IPOL was given and during the injection the liquid squirted out of the syringe where the needle was attached all over the patient's arm and floor. The reporter then gave the patient a second injection of IPOL in the other arm. The reporter was reporting the event and wanting to know if the second shot given would cause a problem.  On 04-AUG-2021 the patient developed a serious event reported as sustained a minute long seizure (seizure) on the same day in the evening following the administration of IPV (VERO). This event was assessed as medically significant.  On 04-AUG-2021 the patient developed a non-serious event reported as temperature of 101.5 Fahrenheit (pyrexia) on the same day in the evening following the administration of IPV (VERO).  It was reported, the patient's mom took the patient to the ED (emergency department) that evening due to having a temperature of 101.5 Fahrenheit and the child sustained a minute long seizure.  Other relevant laboratory test were not reported.  It was not reported if the patient received a corrective treatment for the events.  At time of reporting, the patient was recovering from events.; Sender's Comments: This case concerns a six-year-old female patient who seizure and pyrexia after receiving IPOL. It was also the case of exposure via skin contact and needle issue. the patient's body temperature was 101.5 degree Fahrenheit. The time to onset is compatible with the role of the vaccine. Concomitant medications included VARICELLA ZOSTER VACCINE for prophylactic vaccination. Additional information regarding medical history, past medical treatment(s), vaccination(s), condition at the time of vaccination and other laboratory data excluding other predisposing etiologies would be needed for complete assessment of the case. Based upon the reported information, the role of vaccine cannot be assessed