Age: 56.0
Sex: U
Vaccine: COVID19, COVID19
Symptoms: Visual impairment, X-ray
Clinical narrative: X ray (clavicle): cyst; increased and erratic heart rate and blood pressure; increased and erratic heart rate and blood pressure; increased and erratic heart rate and blood pressure; neuropathy; headaches; nausea; constipation; diarrhea; increased depression and anxiety; increased depression and anxiety; chest pain; inability to focus; fatigue; sleep difficulties; increased issues with arthritis; lightheaded; head pressure; increased tinnitus; cold and heat intolerance; muscle spasms; muscle twitches; dry eyes; lack of steadiness; brain fog; hair loss; vision disturbances; blurry vision; The initial case was missing the following minimum criteria: no adverse event. Upon receipt of follow-up information on 30Jan2024, this case now contains all required information to be considered valid.  This is a spontaneous report received from a Consumer or other non HCP, Program ID:.  A 56-year-old patient received BNT162b2 (COMIRNATY), on 17Jun2021 PM as dose 2, single (Lot number: EW0181) at the age of 56 years intramuscular, in left arm for covid-19 immunisation. The patient's relevant medical history included: "hypertension" (ongoing); "anxiety/depression", start date: 2020 (ongoing). The patient's family history included: "coronary artery disease" (unspecified if ongoing), notes: both parents; "heart attack" (unspecified if ongoing), notes: both parents; "diabetes type II" (unspecified if ongoing), notes: Mother. The patient's concomitant medications were not reported. Vaccination history included: comirnaty (Lot EW0202, Intramuscular, Left arm), administration date: 27May2021, for covid-19 immunization. The following information was reported: VISION BLURRED (non-serious) with onset Jun2021, outcome "not recovered", described as "blurry vision"; BRAIN FOG (non-serious) with onset Jun2021, outcome "not recovered"; CHEST PAIN (non-serious) with onset Jun2021, outcome "not recovered"; TEMPERATURE INTOLERANCE (non-serious) with onset Jun2021, outcome "not recovered", described as "cold and heat intolerance"; CONSTIPATION (non-serious) with onset Jun2021, outcome "not recovered"; DIARRHOEA (non-serious) with onset Jun2021, outcome "not recovered", described as "diarrhea"; DRY EYE (non-serious) with onset Jun2021, outcome "not recovered", described as "dry eyes"; FATIGUE (non-serious) with onset Jun2021, outcome "not recovered"; ALOPECIA (non-serious) with onset Jun2021, outcome "not recovered", described as "hair loss"; HEAD DISCOMFORT (non-serious) with onset Jun2021, outcome "not recovered", described as "head pressure"; HEADACHE (non-serious) with onset Jun2021, outcome "not recovered", described as "headaches"; DISTURBANCE IN ATTENTION (non-serious) with onset Jun2021, outcome "not recovered", described as "inability to focus"; HEART RATE INCREASED (medically significant), HEART RATE IRREGULAR (medically significant), BLOOD PRESSURE INCREASED (medically significant) all with onset Jun2021, outcome "not recovered" and all described as "increased and erratic heart rate and blood pressure"; DEPRESSION (non-serious), ANXIETY (non-serious) all with onset Jun2021, outcome "not recovered" and all described as "increased depression and anxiety"; ARTHRITIS (non-serious) with onset Jun2021, outcome "not recovered", described as "increased issues with arthritis"; TINNITUS (non-serious) with onset Jun2021, outcome "not recovered", described as "increased tinnitus"; BALANCE DISORDER (non-serious) with onset Jun2021, outcome "not recovered", described as "lack of steadiness"; DIZZINESS (non-serious) with onset Jun2021, outcome "not recovered", described as "lightheaded"; MUSCLE SPASMS (non-serious) with onset Jun2021, outcome "not recovered"; MUSCLE TWITCHING (non-serious) with onset Jun2021, outcome "not recovered", described as "muscle twitches"; NAUSEA (non-serious) with onset Jun2021, outcome "not recovered"; NEUROPATHY PERIPHERAL (medically significant) with onset Jun2021, outcome "not recovered", described as "neuropathy"; SLEEP DISORDER (non-serious) with onset Jun2021, outcome "not recovered", described as "sleep difficulties"; VISUAL IMPAIRMENT (non-serious) with onset Jun2021, outcome "not recovered", described as "vision disturbances"; BONE CYST (non-serious) with onset 19Jun2021, outcome "unknown", described as "X ray (clavicle): cyst". The events "increased and erratic heart rate and blood pressure" required emergency room visit. Clinical details: Symptoms developed within 24 hours of second injection. Patient had ongoing headache, nausea, constipation, diarrhea, increased depression and anxiety, episodes of increased and erratic heart rate and blood pressure, chest pian, inability to focus, fatigue, sleep difficulties, altered sense of smell since positive case, increased issues with arthritis, lightheaded, head pressure, increased tinnitus, cold and heat intolerance, muscle spasms and twitches, dry eyes, lack of steadiness, neuropathy, brain fog, hair loss, vision disturbances and blurry vision. Patient had 5 trips to emergency room between Jul2023 and Dec2023 (12Jul2023, 17Jul2023, 27Jul2023 and 10Dec2023) due to elevated and erratic heart rate and blood pressure. Cardiac catheterization was performed on 15Aug2023. The patient underwent the following laboratory tests and procedures: Blood test: (Oct2022) Unknown results; (2023) Unknown results; Bone densitometry: (Jan2022) Unknown results; Cardiac stress test: (Oct2022) Unknown results; Computerised tomogram: (29Nov2022) Unknown results; Computerised tomogram thorax: (Jul2023) Unknown results; Echocardiogram: (Oct2022) Unknown results; Magnetic resonance imaging: (30Jun2021) Unknown results; (06Nov2022) Unknown results; Ultrasound Doppler: (22Jun2021) Unknown results; X-ray: (2022) Unknown results, notes: reported date as 21-"ambiguous"-2022; (19Jun2021) cyst. Therapeutic measures were taken as a result of heart rate increased, heart rate irregular, blood pressure increased.; Sender's Comments: Linked Report(s) : US-PFIZER INC-PV202400014225 Same patient & drug / different event and dose.;