Age: 60.0
Sex: M
Vaccine: COVID19
Symptoms: Condition aggravated, Loss of personal independence in daily activities, Pemphigus
Clinical narrative: Pemphigus vulgari; "I have a real bad issue life long issue"; Blister is eating up skin and is getting worse started with 2 bumps and is now covering whole forehead face and chest; This spontaneous case was reported by a consumer and describes the occurrence of PEMPHIGUS (Pemphigus vulgari) in a 60-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 036E21A and 027A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 08-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 05-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PEMPHIGUS (Pemphigus vulgari) (seriousness criterion medically significant), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES ("I have a real bad issue life long issue") and CONDITION AGGRAVATED (Blister is eating up skin and is getting worse started with 2 bumps and is now covering whole forehead face and chest). At the time of the report, PEMPHIGUS (Pemphigus vulgari), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES ("I have a real bad issue life long issue") and CONDITION AGGRAVATED (Blister is eating up skin and is getting worse started with 2 bumps and is now covering whole forehead face and chest) outcome was unknown.            Patient had received both doses of the Moderna COVID 19 vaccine  and was diagnosed with pemphigus vulgari. It took months to diagnosed him, he had to go to a dermatologist and an infectious disease doctor to get diagnosed. No concomitant medication information provided. No treatment medication information provided.  Company Comment: This case concerns a 60-year-old, male patient with no relevant medical history, who experienced the unexpected event of Pemphigus Vulgaris. The event occurred on an unknown number of days after the second dose of Moderna COVID-19 Vaccine. The event was considered related to the product per the reporter's assessment. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 13-Sep-2021: Follow-up received on 13 Sep 2021 contains updated information on reporter details, vaccine information and new event:  Activities of daily living impaired. On 13-Sep-2021: Follow-up received on 13 Sep 2021 contains no new information. On 15-Sep-2021: Follow-up was received on 15 September 2021 and events were added.; Sender's Comments: This case concerns a 60-year-old, male patient with no relevant medical history, who experienced the unexpected event of Pemphigus Vulgaris. The event occurred on an unknown number of days after the second dose of Moderna COVID-19 Vaccine. The event was considered related to the product per the reporter's assessment. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.