Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Pyrexia, Rash pruritic
Clinical narrative: burning pain/ burning rash; pain in her legs and feet; eye blister; She has insomnia due to the pain; rash where blisters are/ fluid filled blister on both leg, feet, scalp, eyes and genital area; Blister on genital; couldn't concentrate; dizzy; she felt achy/burning pain/pain; developed heart palpitations; nauseated; had no appetite; This non-serious case was reported by a consumer via call center representative and described the occurrence of nausea in a elderly female patient who received Herpes zoster (Shingrix) for prophylaxis.   On 19-AUG-2023, the patient received the 1st dose of Shingrix (intramuscular, unknown deltoid). On 20-AUG-2023, 1 days after receiving Shingrix, the patient experienced nausea (Verbatim: nauseated), appetite absent (Verbatim: had no appetite), concentration ability impaired (Verbatim: couldn't concentrate), dizziness (Verbatim: dizzy), pain (Verbatim: she felt achy/burning pain/pain) and palpitation (Verbatim: developed heart palpitations). On 21-AUG-2023, the patient experienced insomnia (Verbatim: She has insomnia due to the pain), blistery rash (Verbatim: rash where blisters are/ fluid filled blister on both leg, feet, scalp, eyes and genital area), genital blister (Verbatim: Blister on genital) and eye disorder (Verbatim: eye blister). On an unknown date, the patient experienced burning skin (Verbatim: burning pain/ burning rash) and pain of lower extremities (Verbatim: pain in her legs and feet).  The patient was treated with benadryl (nos) (Benadryl), medication unknown (Cream (Medication Unknown)) and paracetamol (Tylenol). The outcome of the nausea, appetite absent, dizziness, pain and palpitation were resolved (duration 3 days) and the outcome of the concentration ability impaired was resolved and the outcome of the insomnia, blistery rash, genital blister, burning skin and eye disorder were not resolved and the outcome of the pain of lower extremities was not reported.   It was unknown if the reporter considered the nausea, appetite absent, concentration ability impaired, dizziness, pain, palpitation, insomnia, blistery rash, genital blister, burning skin, pain of lower extremities and eye disorder to be related to Shingrix.     It was unknown if the company considered the nausea, appetite absent, concentration ability impaired, dizziness, pain, palpitation, insomnia, blistery rash, genital blister, burning skin, pain of lower extremities and eye disorder to be related to Shingrix.   Additional Information: GSK Receipt Date: 08-SEP-2023 The reporter was the patient.  She declined to provide her DOB (date of birth) but described herself as a senior citizen.  The patient received Shingrix dose.  The next day, she felt achy, dizzy, nauseated, had no appetite and developed heart palpitations.  All of these effects lasted about three days and they had resolved.  Two days after vaccination, on 21st August 2023, she developed large fluid-filled  blisters on both legs, feet, scalp, eyes and genital area.  She had burning pain and rash where the blisters were.  She had insomnia due to the pain.  Some of the blisters have healed but the burning rash still comes and goes.  On 1st September 2023 she went to a walk-in clinic.  The healthcare professional (nurse practitioner) said she had a one in a million reaction to the Shingrix vaccination.  She was given four unknown prescription creams for the rash. She treated the pain in her legs and feet with Tylenol and ice water baths.  She treated the insomnia with Benadryl.  Nothing else was reported. The Lot number was unknown. She declined to provide her mailing address as she was living in temporary housing.  The reporter consented to follow-up with her via email.