Sex: F
Vaccine: FLUR3, VARZOS
Symptoms: Fall, Gait disturbance, Hemiparesis, Immediate post-injection reaction, Laboratory test abnormal
Clinical narrative: was confirmed to have nerve damage; she fell down on the floor /  she had fallen down 7 to 8 times / She would fall on her chair sometimes / A week ago she fell again; She went from running and cooking to being barely able to do any activities; started experiencing left side leg weakness; she is dragging her left leg a lot; experienced arm pain which lasted for about a month; This case was reported by a consumer via call center representative and described the occurrence of nerve damage in a 64-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included INFLUENZA VACCINE (FLUBLOK) for prophylaxis.   The patient's past medical history included breast cancer (had right side breast cancer in January of 2013), lymph node excision (went through chemotherapy and had 34 lymph nodes removed) and radiation therapy (had scarring in her throat). Previously administered products included Shingles vaccine (had the previous Shingles vaccine in 2016), Shingrix (first dose of Shingrix on 7th June 2018) and steroid (has also gotten steroid shot in 2015).   On 20th October 2018, the patient received the 2nd dose of Shingrix (intramuscular) .5 ml and FLUBLOK (intramuscular). In October 2018, immediately after receiving Shingrix, the patient experienced pain in arm. In November 2018, the patient experienced lower extremities weakness of and leg dragging. On 20th January 2019, the patient experienced fall and activities of daily living impaired. On an unknown date, the patient experienced nerve damage. The patient was treated with steroid shot (nos). On an unknown date, the outcome of the nerve damage, lower extremities weakness of, leg dragging, fall and activities of daily living impaired were unknown and the outcome of the pain in arm was recovered/resolved.   It was unknown if the reporter considered the nerve damage, pain in arm, lower extremities weakness of, leg dragging, fall and activities of daily living impaired to be related to Shingrix.  Additional details were provided as follows: The patient received Shingrix vaccine on 20th October 2018.  She also received Flublok vaccine on the same day.  Her pharmacist told her that she received the Flu vaccine on 10 October 2018 but she stated that she received them on the same date.  Right after getting the vaccine she experienced arm pain which lasted for about a month.  By November/December of 2018, she started experiencing left side leg weakness. Her daughter told her that she was dragging her left leg a lot.  She saw her orthopedic surgeon on Jan 15, 2019. She was given a steroid shot.  She fell down on the floor and was picked up by her husband.  From January 2019 till April 2019 she had fallen down 7 to 8 times. She would fall on her chair sometimes.  Her entire left side of body was weak, such as weakness in mouth, arm, and leg.  She went from running and cooking to being barely able to do any activities.  She cannot even pick up an onion. She thought she had a stroke so she went to Hospital, and it was confirmed that she did not have a stroke.  They were unable to determine what was happening to her. She was told to do MRI but since she did not have insurance she did not get an MRI done.  In May of 2019 she went to the hospital again and was confirmed to have nerve damage. She has been to 2-3 doctors and has been confirmed that she does not have a stroke. She went to new doctor in January of 2020 and was confirmed nerve damage in left leg after testing. The physician has referred her to a neurologist. A week ago she fell again.    No further details were provided.  It was unknown if the reporter considered the pain in arm, lower extremities weakness of, leg dragging, fall, nerve damage and activities of daily living impaired to be related to Shingrix.