Sex: F
Vaccine: COVID19
Symptoms: Drug ineffective, SARS-CoV-2 test, Suspected COVID-19
Clinical narrative: caller has completed 5 days of the Paxlovid treatment; caller has completed 5 days of the Paxlovid treatment; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 75-year-old female patient received BNT162b2 (BNT162B2), as dose 1, single (Batch/Lot number: unknown), as dose 2, single (Batch/Lot number: unknown), in right arm and as dose 3 (booster), single (Batch/Lot number: unknown), in right arm for covid-19 immunisation. The patient's relevant medical history included: "Blood pressure" (ongoing), notes: Blood pressure, began prior to taking Paxlovid. The patient's concomitant medications were not reported. Vaccination history included: Flu shot (Thinks she got a flu shot in Sep2021), administration date: Sep2021, for Immunization. The following information was reported: DRUG INEFFECTIVE (medically significant), SUSPECTED COVID-19 (medically significant), outcome "unknown" and all described as "caller has completed 5 days of the Paxlovid treatment". The patient underwent the following laboratory tests and procedures: SARS-CoV-2 test: negative, notes: 3 days after Paxlovid treatment. Therapeutic measures were taken as a result of suspected covid-19.  Clinical information: Stated the patient has completed 5 days of the Paxlovid treatment and still feels terrible and has a terrible sense of taste, experiencing diarrhea and now muscle aches; on day 3 tested negative for covid, however lost her appetite completely and reports she can't eat a lot and she was not eating; states she does not feel as good as she generally goes out and walks and this medication Paxlovid was slowing her down. Ptient verified the information provided by the transferring agent and states in going through it her sense of taste was altered and food did not taste that good. HCP information: Patient stated she has no further HCP information to provide; in looking on how to spell the HCP's name, caller states the HCP made sure she was ok and she talked to him twice prior to him prescribing the Paxlovid drug; stated she does not have any huge medical problems except blood pressure and that was the only medication she was taking before the Paxlovid which was her blood pressure medicine; stated she asked the HCP if it was ok to continue taking her blood pressure medication and she checks her blood pressure and it didn't appear that Paxlovid bothered her blood pressure and she was checking it and it was normal. Patient stated Pfizer has her pull out all her medical information and in looking for her doctor's name, states the doctor's name was on her medication and she is due a follow up; stated she needs her glasses to read the doctor's name from the prescription bottle for her blood pressure medication and states it was supposed to be on the bottle itself; clarifies she was reading her blood pressure medication bottle and it was a pharmacy bottle with the pharmacy label on it and she needs her glasses to read it but confirmed it was a pharmacy bottle with a pharmacy label on it. Patient stated she has no energy. States the terrible sense of taste began starting on day 1 of taking the Paxlovid which was on 01Jun2022 and all through the five days she took Paxlovid it was awful and the terrible taste was terrible and she knew she had to eat something and tried to eat something and tried to eat in the morning after she took the Paxlovid. Stated she had a little of the diarrhea and that started when she started taking Paxlovid and it was not that bad and was not ongoing and resolved she thinks on Day 5 of taking the Paxlovid when she stopped taking it on Sunday 05Jun2022. Stated she started taking Paxlovid on 01Jun2022 and the last day of taking it was on 05Jun2022; states she has muscle aches and thinks as she remembers she does have little twinges and does walk and what have you and would not have known she had covid unless she took a test as she was in a crowd of people and this was before Paxlovid regarding testing positive for covid; stated she sometimes has aches and pains and now feels everything and it was ongoing and thinks they look like they are worse. Stated for her lost appetite, she thinks it started the first day of taking Paxlovid and does not take a lot of medication and does not take Aspirin or Tylenol and this was ongoing and worse for appetite. Stated she was putting on her glasses so she can read the information to this agent from the Paxlovid package and agent did ask the caller if having to read with glasses began prior to taking Paxlovid and despite further attempts at clarification, caller stated when the doctor prescribed Paxlovid she went online to read it and wanted to know what she was putting in her body and discussed it and he thought the Paxlovid was best for her to take. Patient stated the Paxlovid can't be crushed up so they are tablets and they said this was one of the blister packs and was the morning blister and she had to take one blister or packet in the morning and it was Ritonavir tablets 100mg and took two of the Nirmatrelvir that was 150mg per tablet; states the indication for Paxlovid was that her doctor recommended it and she guesses based on her history that he chose that. Stated she did not have symptoms and what happened was her daughter is an elected official and they had an election party and at the end and she chose not to wear a mask and somebody was infected, clarified this occurred before taking Paxlovid and somebody was infected and she got a break through case; stated she had two of the Pfizer Covid shots and the Pfizer covid booster and thought she was in good shape. No additional vaccines administered on same date of the Pfizer suspect. Family medical history was none. Patient stated breakthrough case of covid and chose not to wear a mask and somebody was infected. No culture, serotyping was performed. Stated she does not take tylenol or aspirin. Patient clarified she has not gone to the emergency room, hospital or doctor's office. Patient stated she was fine as far as she knows and it trying to get through with the Paxlovid medication still in her body and it was probably working and she does not know how long it stays in the body and it would be interesting to know if after she takes the Paxlovid medication, how long it stays in and when does it excrete from the body; asks when this medication comes out of her system and it will probably be a while and knows the liver has to excrete all medications when she was taking it. Stated she did not have symptoms and what happened was they had an election party and at the end and she chose not to wear a mask, and somebody was infected, caller clarified this occurred before taking Paxlovid and somebody was infected and she got a break through case; Stated she had two of the Pfizer Covid shots and the Pfizer covid booster and thought she was in good shape.    The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.