chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 79.0
Sex: M
Vaccine: PPV, TDAP
Symptoms: Pruritus, Pyrexia
Clinical narrative: Starting a few hours after pneumonia shot pt started having significant pain and swelling of entire (R) arm. Pt was unable to move arm and entire underside of arm filled with fluid such that skin was distended approx. 1 inch beyond normal. Pt also had fever, loss of appetite x 1 wk. As swelling subsided, pt's entire arm began itching. Pain unrelieved by pain reliever (unknown med name/dose).
Age: 27.0
Sex: F
Vaccine: UNK
Symptoms: Cellulitis, Erythema, Induration
Clinical narrative: Cellulitis - arm with 10 cm of surrounding erythema/central area 2.0 cm x 2.0 cm - increased induration.
Age: 46.0
Sex: F
Vaccine: TDAP
Symptoms: Arthralgia, Injection site erythema, Injection site pain, Injection site swelling, Myalgia
Clinical narrative: Evening of 11/9/2015, nausea, vomiting, muscle and joint aching. No N/V now but still with muscle and joint aching 11/12/2015. Area of (L) deltoid is pink in color, painful, swelling 11/12/15 still having muscle and joint aches and pains and swelling at site.
Age: 46.0
Sex: F
Vaccine: TDAP
Symptoms: Nausea, Vomiting
Clinical narrative: Evening of 11/9/2015, nausea, vomiting, muscle and joint aching. No N/V now but still with muscle and joint aching 11/12/2015. Area of (L) deltoid is pink in color, painful, swelling 11/12/15 still having muscle and joint aches and pains and swelling at site.
Age: 77.0
Sex: F
Vaccine: FLU3
Symptoms: Asthenia, Cough, Nasal congestion, Pain, Rhinorrhoea
Clinical narrative: Feeling of weakness, runny nose and over all achiness - also a slight cough; (Lasted over two weeks). Nasal congestion.
Age: 63.0
Sex: F
Vaccine: PNC13
Symptoms: Erythema, Myoclonus
Clinical narrative: Given PREVNAR 13 on 12/9/2014 and had a "grapefruit" sized area of redness that lasted x 3 days. Also had myoclonic jerks x 1 night. (Pt just reported to our office at a recent visit).
Age: 21.0
Sex: F
Vaccine: HEPAB
Symptoms: Dizziness
Clinical narrative: Dizziness, lightheadedness. Duration 20 min. Pt. sip water and lay flat resolved with no issue.
Age: 80.0
Sex: F
Vaccine: VARZOS
Symptoms: Ear discomfort, Fatigue, Feeling abnormal, Influenza like illness
Clinical narrative: Flu-like symptoms/ "Don't feel good", "ear feels clogged", "tired and wants to rest".
Age: 82.0
Sex: M
Vaccine: PNC13
Symptoms: Differential white blood cell count normal, Erythema, Full blood count normal, Rash erythematous, Rash pruritic
Clinical narrative: Patient developed redness, spreading gradually over the course of 6 days following injection. Symptoms began the evening of receiving and demonstrates a pruritic 10 cm x 20 cm red/erythematous rash.
Age: 47.0
Sex: M
Vaccine: FLU3
Symptoms: Bedridden, Cough, Fatigue, Headache, Hepatic enzyme increased
Clinical narrative: The morning after flu vaccination, he had fever, headache, and tiredness. He developed a dry cough by the 2nd day. All these symptoms continued and worsened until he was bedridden on the 4th day. On the 5th day, he went to urgent care because symptoms worst of any day and fever 104 degrees. His physician ordered labs and he was admitted to the hospital that evening. He had elevated liver enzymes, low WBC, and low platelets. They ran tests for 2 days with none of them positive.  He was released on the 3rd day with no answers.
Age: 47.0
Sex: M
Vaccine: FLU3
Symptoms: Platelet count decreased, Pyrexia, White blood cell count decreased
Clinical narrative: The morning after flu vaccination, he had fever, headache, and tiredness. He developed a dry cough by the 2nd day. All these symptoms continued and worsened until he was bedridden on the 4th day. On the 5th day, he went to urgent care because symptoms worst of any day and fever 104 degrees. His physician ordered labs and he was admitted to the hospital that evening. He had elevated liver enzymes, low WBC, and low platelets. They ran tests for 2 days with none of them positive.  He was released on the 3rd day with no answers.
Age: 72.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site erythema
Clinical narrative: Patient has redness on site of injection.
Age: 4.0
Sex: M
Vaccine: DTAP, HEPA, IPV, MMRV
Symptoms: Injection site erythema, Injection site oedema, Injection site pain
Clinical narrative: Erythema, edema and tender at injection site of DTaP- (L) upper arm. BENADRYL given x3 days.
Age: 67.0
Sex: F
Vaccine: PNC13
Symptoms: Injection site atrophy
Clinical narrative: Noticed one month after the injection was given that arm had indention and has gotten worse over the past months. Her personal trainer told her it was from injection. Per patient nothing initial after immunization.
Age: 65.0
Sex: F
Vaccine: PNC13, VARZOS
Symptoms: Injection site swelling, Pruritus, Swelling
Clinical narrative: Swelling and itching worsens at night 3 inch diameter slightly raised circle surrounding injection site.
Age: 73.0
Sex: F
Vaccine: FLU3, PNC13
Symptoms: Injection site erythema, Injection site hypersensitivity, Injection site swelling, Injection site warmth, Local reaction
Clinical narrative: Given: PREVNAR 13 11/5/15, localized allergic reaction (R) upper arm. Complaining of red, swelling and warmth (R) upper arm. Treated with diphenhydramine 25mg tablet. Use as needed.
Age: 31.0
Sex: F
Vaccine: HPV4
Symptoms: Anxiety, Palpitations, Skin papilloma
Clinical narrative: 03/16/15 Heart racing and anxiety starting about a week prior. Around 05/23/15 noticed warts on stomach; OBG and dermatologist diagnosed as (flat) warts (on 06/05/15). I have been treating them since then, yet they have persisted. They have spread to chest, neck, chin, arms, back, and genital area.
Age: 73.0
Sex: F
Vaccine: TDAP
Symptoms: Asthenia, Atrial fibrillation, Condition aggravated, Electrocardiogram abnormal, Fatigue
Clinical narrative: Had TDAP, had sensation like rushing warm water down arm. Soon after started feeling tired and weak, "felt like flu" about 1hr later, felt heart rate was - irregular (has hx of afib with pacemaker). Got home felt worse, called cardiologist. Seen in office next morning in afib by EKG. Per pacer-afib during night.
Age: 73.0
Sex: F
Vaccine: TDAP
Symptoms: Heart rate irregular, Influenza like illness
Clinical narrative: Had TDAP, had sensation like rushing warm water down arm. Soon after started feeling tired and weak, "felt like flu" about 1hr later, felt heart rate was - irregular (has hx of afib with pacemaker). Got home felt worse, called cardiologist. Seen in office next morning in afib by EKG. Per pacer-afib during night.
Age: 75.0
Sex: F
Vaccine: PNC13
Symptoms: Erythema, Pruritus, Skin warm
Clinical narrative: Red arm from shoulder to past elbow. No swelling, no tenderness, no loss of function. Arm is hot to the touch and patient is itching. Clindamycin QID x 5 days.
Age: 35.0
Sex: F
Vaccine: TDAP
Symptoms: Hypoaesthesia, Neurological examination normal, Pain, Paraesthesia
Clinical narrative: Pain, numbness and tingling in arm starting evening after Tdap vaccine, tingling in fingers persisting for 2 days and intermittently recurring.
Age: 77.0
Sex: F
Vaccine: PNC13
Symptoms: Headache, Nausea, Pain, Rash
Clinical narrative: Rash, headache, achy, nausea.
Age: 13.0
Sex: F
Vaccine: DTAPHEPBIP
Symptoms: Wrong drug administered
Clinical narrative: Gave DTAPHBIP (PEDIARIX) to 13 yr should have given Tdap, Hep B and IVP.
Age: 47.0
Sex: F
Vaccine: FLU4
Symptoms: Dizziness, Dyspnoea, Hyperhidrosis, Hypoaesthesia oral, Stridor
Clinical narrative: Pt was in the waiting room after receiving the flu shot IM in right deltoid.  Pt c/o feeling light headed and bad in general.  Pt sitting up in a chair, breathing and talking.  C/o lips feeling numb and states "Give me something for allergy".  No hives or swelling of the lips or face.  Stated she is allergic to cortisone.  Had assistant call Code Blue.  911 was called.  Medical staff responded including the NP, who assessed the patient.  Resp 22 and pulse 80.  Patient stated she was having trouble breathing and was diaphoretic.  Administered epinephrine 0.3 mg IM via EpiPen to right outer thigh.  Oxygen 4L/min was applied via nasal canula per NP.  VS:  120/70, p 100 r 40.  Pt remained responsive, eyes closed but able to answer questions.  Ox saturation was 98-100%.  Ambulance crew arrived.  Report given.  HP reported pt did have some stridor on exam.  When pt was asked if she had had a flu shot in the past, she responded yes.  Pt transported to the hospital via rescue squad.
Age: 67.0
Sex: M
Vaccine: FLU3, PNC13
Symptoms: Pain in extremity
Clinical narrative: Patient reports arm pain starting the day after the immunization and continuing until today (11/17/15). Patient thought it would get better, but it continued to get worse. Went to visit with his primary care doctor in October to follow up regarding reaction. Doctor is planning on performing an x-ray.
Age: 7.0
Sex: M
Vaccine: FLU3
Symptoms: Pyrexia, Urticaria
Clinical narrative: Had slight fever 11/11/2015, Hives on 11/13/2015.
Age: 38.0
Sex: F
Vaccine: TDAP
Symptoms: Injection site erythema, Vaccination site pain, Vaccination site swelling
Clinical narrative: Pain, redness and swelling greater than expected at vaccine site.
Age: 62.0
Sex: F
Vaccine: VARZOS
Symptoms: Dysphagia, Dyspnoea
Clinical narrative: Administered a Zostavax vaccine to a 62 year old female who has no contraindications to receive the singles vaccine.  She called me at 1:30 pm to tell me she had a "reaction" to the shot. She left here and went to a restaurant, bought an iced tea, got on the interstate and was unable to swallow her drink, she drove to her Dr. office.  She said they gave her Benadryl and they called 911, who observed her for a while and Dr. sent her home. I spoke with LPN who confirmed that the pt did there with c/o SOB. Blood pressure 200/110, 02 sat 98% and gave her 02 and 50mg. oral Benadryl.
Age: 26.0
Sex: M
Vaccine: JEV1
Symptoms: Rash erythematous
Clinical narrative: Just noticed small little red spots on his chest back and arms. Not itching.
Age: 61.0
Sex: F
Vaccine: FLUX
Symptoms: Chills, Myalgia, Nausea
Clinical narrative: Chills, muscle aches, nausea.
Age: 38.0
Sex: M
Vaccine: FLU4
Symptoms: Lymph node pain, Lymph node palpable, Lymphadenopathy
Clinical narrative: Left axillary lymph node enlargement with accompanied pain (injection was administered on the left side). Started with one enlarged lypmh node and progressed to 3 or 4 smaller ones along the same chain. No fevers, sweats or other symptoms noted.
Age: 4.0
Sex: F
Vaccine: DTAPIPV
Symptoms: Injection site erythema, Pain in extremity, Pyrexia, Skin warm
Clinical narrative: 11.17.15  1:30pm  CST  --  Hello, I am writing to report patient is experiencing reactions to the Vaccine administered yesterday, 11.16.15 at her 4yr Check-Up.  She was fine last night, playing, singing, happy, active, etc...   Before bed she began complaining of her leg being sore and hurting.  I know tenderness is a side effect of the vaccines being injected into the muscle.  Patient awoke earlier than usual this morning with a fever and the injection site redness, tenderness and a headache (she said).  She refused eating, but did take her fluids, and was uncomfortable and had a fever of 100.6 degrees.  Her entire body was very warm to the touch.  I gave her the recommended dosage of Tylenol (as discussed in her visit with you).  This did not seem to help.  When I checked her temperature again 2 hours later, she was down only to 99.8.  She's been laying covered up, on the couch all day so far - absolutely not like herself (usually she's going and going and going all day).  Finally, it seems the Tylenol is helping SOMEWHAT and I got her to eat some broth n noodles soup.  She is finally sitting up on the couch and wanting to play a little.  I will continue to monitor her as always.
Age: 65.0
Sex: M
Vaccine: FLUX
Symptoms: Headache, Pain, Sinus congestion, Throat irritation
Clinical narrative: Headache, Sinus congestion, body aches, scratchy throat.
Age: 69.0
Sex: F
Vaccine: PPV
Symptoms: Mobility decreased, Pain in extremity, Peripheral swelling, Rash
Clinical narrative: PATIENT SAYS HER ARM WAS SO SORE SHE WAS UNABLE TO MOVE IT. IT WAS SWOLLEN AND HAD A RASH FROM THE ELBOW TO THE SHOULDER.
Age: 43.0
Sex: F
Vaccine: FLU4
Symptoms: Hypersensitivity, Injection site erythema, Injection site hypoaesthesia, Injection site pain, Injection site pruritus
Clinical narrative: The upper arm started to become red and blotchy around the site of the injection, then the reaction started spreading.  She took Benadryl, the redness continued to spread, warm to touch and appears to have streaks, although she has been scratching at it, it is painful moreso than itches.  Temperature was 98.0, does not feel feverish. Dr diagnosed an allergic reaction. Persisted for one week with swelling and numbness. She was prescribed prednisone.
Age: 43.0
Sex: F
Vaccine: FLU4
Symptoms: Injection site reaction, Injection site streaking, Injection site swelling, Injection site warmth, Rash macular
Clinical narrative: The upper arm started to become red and blotchy around the site of the injection, then the reaction started spreading.  She took Benadryl, the redness continued to spread, warm to touch and appears to have streaks, although she has been scratching at it, it is painful moreso than itches.  Temperature was 98.0, does not feel feverish. Dr diagnosed an allergic reaction. Persisted for one week with swelling and numbness. She was prescribed prednisone.
Sex: U
Vaccine: VARZOS
Symptoms: Expired product administered, No adverse event
Clinical narrative: This spontaneous report as received from a healthcare student refers to a patient of unknown age. On 11-NOV-2015 the patient was vaccinated with expired ZOSTAVAX (lot # K010968, expiry date: 07-NOV-2015) (expired product administered). No adverse symptoms reported. ZOSTAVAX was supported with in-house post-expiry data. The outcome was unknown. No product quality complaint was involved. Additional information has been requested.
Age: 68.0
Sex: F
Vaccine: FLU3
Symptoms: Chills, Headache, Hyperhidrosis, Pyrexia
Clinical narrative: Pt was given HIGH DOSE FLUZONE 11/3/15. That same evening developed bad headache fever chills sweats x 12 hours.
Age: 50.0
Sex: F
Vaccine: FLU3
Symptoms: Haematoma, Injected limb mobility decreased, Injection site pain, Nuclear magnetic resonance imaging abnormal
Clinical narrative: Pt. reports that she received her yearly influenza vaccine on 10/28/15 during flu clinic and was fine until 1 week later when she developed severe right upper arm pain and had difficulty moving or lifting her arm. Pt. went to the orthopedist for evaluation and had MRI dine which showed a hematoma which the doctor thinks is r/+ the vaccine. Pt. treated anti-inflammatory medication (can't remember name) and has an appt. for repeat MRI with contrast scheduled on 11/7/15.
Age: 76.0
Sex: F
Vaccine: PNC13
Symptoms: Asthenia, Disturbance in attention, Facial paresis, Headache, Hypotonia
Clinical narrative: 11/17/15 Had hospital F/U O.V. today with PCP. Patient is a 76-year-old female who presented to the hospital on November 10, 2015 for generalized weakness. The patient is alert and oriented x3, however she does not recall the details of yesterday and she does not recall all the details leading up to her presentation to the hospital today. She is able to provide some meaningful history which is supplemented by her husband. Yesterday the patient was in her usual state of health. She went to a dentist appointment on a routine primary care visit appointment with Dr. On that appointment she was administered the pneumonia vaccine. She typically wakes up around 0700, however this morning she woke up at 0830. Her husband noted that she wasn't up during her usual time and was listening out for her, and he heard her weakly calling for him. He went to her bedside and she stated that she had an episode of urinary incontinence and also bit her tongue during the night and bled onto the pillow. Nothing like this has ever happened to her before. She denies any previous seizure. He noted that she was slow to answer, he also asked her to smile and noted that she had some overall facial weakness but did not note asymmetry. He also remarked that she had difficulty concentrating on his questions. She had generalized weakness and he noted her to be "limp". Baseline, she ambulates independently. She is typically very responsive and conversant. She does add that she was previously seen by a cardiologist for possible atrial fibrillation. She states that she had had very rare palpitations and around one year ago and was evaluated by a cardiologist. At that time she was evaluated with presumably an event recorder or loop recorder but states that no intervention ever came of her evaluation. She thinks that a blood pressure agent was suggested but opted to not take any new medications. She has never been on anticoagulation. She denies any personal history of hypertension, dyslipidemia, diabetes mellitus, MI/NSTEMI, CVA/TIA, thyroid disorders. She notes a residual headache since waking up that is "all over my head," without photophobia or vision change. She has chronic LUE shoulder pain for which she had a cortisone injection last week and has some baseline ROM limitations. She denies any chest pain, difficulty breathing, vaginal bleeding, hematuria, hemoptysis, hematochezia, melena, bright red blood per rectum, tingling or numbness. She is currently continent and asking for the bedpan.
Age: 76.0
Sex: F
Vaccine: PNC13
Symptoms: Slow response to stimuli, Tongue biting, Tongue haemorrhage, Urinary incontinence
Clinical narrative: 11/17/15 Had hospital F/U O.V. today with PCP. Patient is a 76-year-old female who presented to the hospital on November 10, 2015 for generalized weakness. The patient is alert and oriented x3, however she does not recall the details of yesterday and she does not recall all the details leading up to her presentation to the hospital today. She is able to provide some meaningful history which is supplemented by her husband. Yesterday the patient was in her usual state of health. She went to a dentist appointment on a routine primary care visit appointment with Dr. On that appointment she was administered the pneumonia vaccine. She typically wakes up around 0700, however this morning she woke up at 0830. Her husband noted that she wasn't up during her usual time and was listening out for her, and he heard her weakly calling for him. He went to her bedside and she stated that she had an episode of urinary incontinence and also bit her tongue during the night and bled onto the pillow. Nothing like this has ever happened to her before. She denies any previous seizure. He noted that she was slow to answer, he also asked her to smile and noted that she had some overall facial weakness but did not note asymmetry. He also remarked that she had difficulty concentrating on his questions. She had generalized weakness and he noted her to be "limp". Baseline, she ambulates independently. She is typically very responsive and conversant. She does add that she was previously seen by a cardiologist for possible atrial fibrillation. She states that she had had very rare palpitations and around one year ago and was evaluated by a cardiologist. At that time she was evaluated with presumably an event recorder or loop recorder but states that no intervention ever came of her evaluation. She thinks that a blood pressure agent was suggested but opted to not take any new medications. She has never been on anticoagulation. She denies any personal history of hypertension, dyslipidemia, diabetes mellitus, MI/NSTEMI, CVA/TIA, thyroid disorders. She notes a residual headache since waking up that is "all over my head," without photophobia or vision change. She has chronic LUE shoulder pain for which she had a cortisone injection last week and has some baseline ROM limitations. She denies any chest pain, difficulty breathing, vaginal bleeding, hematuria, hemoptysis, hematochezia, melena, bright red blood per rectum, tingling or numbness. She is currently continent and asking for the bedpan.
Age: 36.0
Sex: F
Vaccine: FLU4
Symptoms: Chest discomfort, Dyspnoea, Fall, Fatigue, Rash
Clinical narrative: Fatigue and buckling of knees/fall: 6 hours post shot thru next 5 days. Rash on chest, neck, face: 48 hours post shot thru 11/17-still mildly present. Swelling of face: noticed about 48 hrs post shot thru 11/12. Tightness in chest and shortness of breath: 6 to 48 hours post: Did not report until 11/17 but saw doctor who confirmed reaction to flu shot and advised reporting as soon as possible. Put on prednisone 10 days.
Age: 36.0
Sex: F
Vaccine: FLU4
Symptoms: Swelling face, Vaccination complication
Clinical narrative: Fatigue and buckling of knees/fall: 6 hours post shot thru next 5 days. Rash on chest, neck, face: 48 hours post shot thru 11/17-still mildly present. Swelling of face: noticed about 48 hrs post shot thru 11/12. Tightness in chest and shortness of breath: 6 to 48 hours post: Did not report until 11/17 but saw doctor who confirmed reaction to flu shot and advised reporting as soon as possible. Put on prednisone 10 days.
Age: 58.0
Sex: M
Vaccine: FLU4, PNC13
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: Swelling and redness at injection site of PREVNAR 13. Given on 11-12-2015.
Age: 84.0
Sex: F
Vaccine: PNC13
Symptoms: Cellulitis, Erythema
Clinical narrative: Reddened, cellulitis area received after getting PREVNAR 13 vaccine given on 11-10-15. Placed on 7 day ciprofloxacin therapy.
Age: 68.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Chills, Injection site erythema, Injection site swelling, Malaise, Pyrexia
Clinical narrative: Patient had chills, shakiness, and fever of 103 degrees F approximately 4 hours after vaccines. Redness/swollen injection site. Took ibuprofen 200mg every 4 hours. 3 days later still feels sick with temp of 99 degrees F and redness and swollen present.
Age: 68.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Tremor
Clinical narrative: Patient had chills, shakiness, and fever of 103 degrees F approximately 4 hours after vaccines. Redness/swollen injection site. Took ibuprofen 200mg every 4 hours. 3 days later still feels sick with temp of 99 degrees F and redness and swollen present.
Age: 76.0
Sex: M
Vaccine: FLU3
Symptoms: Paraesthesia
Clinical narrative: Tingling feeling from top of left arm a little way to fingers - sensation is lasting 24 hours per day.
Age: 0.77
Sex: F
Vaccine: FLU3
Symptoms: Rash, Rash erythematous, Urticaria, Vomiting
Clinical narrative: 11/9/15 - first ever flu vaccine given LVL. 11/10/15 - vomit x 1 , rash to left wrist, red bumps then spread to right arm, left foot, to back, no trouble breathing, no fever. 11/11/15 - saw doctor for vomiting, hives, doctor unsure if it was a reaction vs. viral illness. BENADRYL given in clinic.
Age: 40.0
Sex: F
Vaccine: FLU4
Symptoms: Rash erythematous
Clinical narrative: Employee presented to Infection Prevention Officer on 10/7/15 after receiving influenza vaccination the previous day (10/6). After vaccination, patient (who is an RN) noticed lacy, red, slightly raised rash on her bilateral posterior shoulder area near armpits. The area of injection was without any rash or inflammation. The rash is not itchy or painful. She did not use any new soap, deodorant, or eat any new foods. Unsure if this is reaction to influenza vaccination or not. Patient took BENADRYL last night before going to bed. Pharmacy supplied her with a dose of cetirizine 10 mg po to be taken at work.
Age: 29.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Blood test, Cardiac monitoring, Chest X-ray, Dizziness, Dyspnoea
Clinical narrative: Sore, itchy burning throat, chest caving in, SOB, losing oxygen, wheezing. Went to urgent care where they prescribed albuterol, Proair inhaler, 5 days of prednisone and cheratussin cough suppressant. Went home still unable to breath after a breathing treatment. Went to bed and woke up Thursday 11/12/2015 with paralysis and paresthesia. Went to the hospital. They did a chest x-ray, blood work and hooked me up to the cardiac monitor. Told me I was obviously having a severe allergic reaction to the Fluvirin injection and sent me home. 8 days later I am still experiencing muscle weakness, face numbness, tingly limbs, severe chest congestion, light headeness, dizziness, SOB, paresthesia and paralysis. Went to the neurologist today for them to tell me to wait it out and see if the symptoms progress into Guillain-Barré syndrome and that it is very possible that I have Miller Fisher Syndrome.
Age: 29.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Hypersensitivity, Hypoaesthesia, Muscular weakness, Oropharyngeal pain, Paraesthesia
Clinical narrative: Sore, itchy burning throat, chest caving in, SOB, losing oxygen, wheezing. Went to urgent care where they prescribed albuterol, Proair inhaler, 5 days of prednisone and cheratussin cough suppressant. Went home still unable to breath after a breathing treatment. Went to bed and woke up Thursday 11/12/2015 with paralysis and paresthesia. Went to the hospital. They did a chest x-ray, blood work and hooked me up to the cardiac monitor. Told me I was obviously having a severe allergic reaction to the Fluvirin injection and sent me home. 8 days later I am still experiencing muscle weakness, face numbness, tingly limbs, severe chest congestion, light headeness, dizziness, SOB, paresthesia and paralysis. Went to the neurologist today for them to tell me to wait it out and see if the symptoms progress into Guillain-Barré syndrome and that it is very possible that I have Miller Fisher Syndrome.
Age: 29.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Paralysis, Respiratory tract congestion, Throat irritation, Wheezing
Clinical narrative: Sore, itchy burning throat, chest caving in, SOB, losing oxygen, wheezing. Went to urgent care where they prescribed albuterol, Proair inhaler, 5 days of prednisone and cheratussin cough suppressant. Went home still unable to breath after a breathing treatment. Went to bed and woke up Thursday 11/12/2015 with paralysis and paresthesia. Went to the hospital. They did a chest x-ray, blood work and hooked me up to the cardiac monitor. Told me I was obviously having a severe allergic reaction to the Fluvirin injection and sent me home. 8 days later I am still experiencing muscle weakness, face numbness, tingly limbs, severe chest congestion, light headeness, dizziness, SOB, paresthesia and paralysis. Went to the neurologist today for them to tell me to wait it out and see if the symptoms progress into Guillain-Barré syndrome and that it is very possible that I have Miller Fisher Syndrome.
Age: 29.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Guillain-Barre syndrome
Clinical narrative: Sore, itchy burning throat, chest caving in, SOB, losing oxygen, wheezing. Went to urgent care where they prescribed albuterol, Proair inhaler, 5 days of prednisone and cheratussin cough suppressant. Went home still unable to breath after a breathing treatment. Went to bed and woke up Thursday 11/12/2015 with paralysis and paresthesia. Went to the hospital. They did a chest x-ray, blood work and hooked me up to the cardiac monitor. Told me I was obviously having a severe allergic reaction to the Fluvirin injection and sent me home. 8 days later I am still experiencing muscle weakness, face numbness, tingly limbs, severe chest congestion, light headeness, dizziness, SOB, paresthesia and paralysis. Went to the neurologist today for them to tell me to wait it out and see if the symptoms progress into Guillain-Barré syndrome and that it is very possible that I have Miller Fisher Syndrome.
Age: 69.0
Sex: F
Vaccine: PPV
Symptoms: Peripheral swelling, Rash, Rash erythematous, Skin tightness
Clinical narrative: LEFT ARM SWELLING AND TIGHTNESS, RED RASH ON INNER ARM LEFT ARM (VAC ADMINISTRATION ARM).
Age: 12.0
Sex: M
Vaccine: FLU4
Symptoms: Asthenia, Blood glucose, Dizziness, Electrocardiogram, Full blood count
Clinical narrative: Patient was seen in Urgent Care Center 11-6-15 for near syncope, dizziness, and weakness.  He had follow up with us on 11-11-15.  We did CBC, Glucose, and EKG dx was Syncope, Headaches.  He came back in on 11-12-15, we did another CBC and glucose and admitted him to Hospital.
Age: 12.0
Sex: M
Vaccine: FLU4
Symptoms: Headache, Presyncope
Clinical narrative: Patient was seen in Urgent Care Center 11-6-15 for near syncope, dizziness, and weakness.  He had follow up with us on 11-11-15.  We did CBC, Glucose, and EKG dx was Syncope, Headaches.  He came back in on 11-12-15, we did another CBC and glucose and admitted him to Hospital.
Age: 4.0
Sex: M
Vaccine: DTAP, FLU4, IPV, MMRV
Symptoms: Cyanosis, Pyrexia, Resuscitation, Seizure
Clinical narrative: Son had seizure that lasted about 3-4 minutes and turned blue, so teachers started CPR. Was taken in ambulance to hospital where it was discovered he had a fever of 102.5.
Age: 65.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Red and swollen left arm from injection site to elbow, very tender some pain.
Age: 67.0
Sex: F
Vaccine: FLU3, PNC13, TDAP
Symptoms: Injected limb mobility decreased, Injection site pain, Pain, Pain in extremity, Sleep disorder
Clinical narrative: Experiecing severe pain from shoulder down to fingers. Specifically in the left arm, but the right are is also affected. Patient had difficulty moving arms without pain and sleeping was also difficult. Right arm resolved by day 8, left arm no improvement after 2 weeks.
Age: 10.0
Sex: M
Vaccine: TYP
Symptoms: Rash erythematous, Rash generalised
Clinical narrative: First pill was administered on 11/9 followed by a second pill on 11/11.  That afternoon a rash developed on inner thighs that was "real red with dots".  Benadryl cream was applied.  On 11/12 the redness was gone, but the area had spread.  The 3rd dose was skipped on 11/13 and by the afternoon the rash had spread all over the body.  There were never respiratory issues.  Benadryl tablets were given and creams were applied as needed.  By 11/15 the redness was gone, but the rash was there and by 11/16 as signs and symptoms were resolved.
Age: 27.0
Sex: M
Vaccine: VARCEL
Symptoms: Asthenia, Headache, Peripheral swelling, Pyrexia
Clinical narrative: Swelling in arm, headache, weakness, low grade fever.
Age: 82.0
Sex: M
Vaccine: FLU3, PNC13
Symptoms: Pain in extremity
Clinical narrative: Patient said his arm was in a little pain after his vaccination.  He also received a Prevnar vaccination in the left arm at the same time, but did not have any pain in that arm.
Age: 64.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site rash
Clinical narrative: RAISED RASHES ON THE AREA/SITE OF INJECTION.
Age: 1.33
Sex: M
Vaccine: DTAP, HIBV, PNC13
Symptoms: Generalised erythema, Irritability, Rash erythematous, Rash generalised, Skin discolouration
Clinical narrative: Rash groin and axillae spread to lips and eyelids, red everywhere and fussy, called 911, taken to ED, given epinephrine, Benadryl, and decadron, he improved on 11/15/15 still a little red rash improving somewhat with Benadryl x3, residual blue spots on abdomen. On hydroxazine.
Age: 62.0
Sex: F
Vaccine: FLUX, VARZOS
Symptoms: Arthralgia, Lymphadenopathy, Oropharyngeal pain, Pyrexia
Clinical narrative: Fever. Swollen glands in neck. Sore throat. Joint pain.
Age: 26.0
Sex: F
Vaccine: FLU4
Symptoms: Rash
Clinical narrative: Patient states that after vaccine was administered, that evening a rash developed on her forearms. The rash continued to spread to her stomach and back over the course of the next two weeks. She sought medical treatment from a dermatologist who treated her with desoximetasome 0.05% ointment. After no resolution she visited another provider who has treated her with Cephalexin 500 mg and Ketoconazole 200 mg. The rash has not resolved.
Age: 68.0
Sex: F
Vaccine: FLU3
Symptoms: Dizziness, Pyrexia
Clinical narrative: Patient's husband called and said she was feeling dizziness so she went to sleep.  On 11/11/2015 patient's husband reported that she was feeling better but had fever.  He was convinced that she had the flu and he was advised that the patient needs to see a doctor for an actual flu diagnosis.
Age: 37.0
Sex: F
Vaccine: FLUX
Symptoms: Back pain, Injection site pain, Neuralgia, Pain, Pain in extremity
Clinical narrative: Dull, throbbing nerve pain shooting down arm of injection into wrist, up through shoulder and to back.
Age: 71.0
Sex: F
Vaccine: FLU3, PNC13
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling
Clinical narrative: Redness, mild swelling and itching in an area the size of 5 x 8 inches around the injection site. Lasting 1 week maybe longer. Applied warm packs to area.
Age: 50.0
Sex: F
Vaccine: FLU3
Symptoms: Drug administered at inappropriate site, Injection site pain, X-ray
Clinical narrative: The patient was given a flu shot right near shoulder joint which was above the deltoid muscle on left arm. Even after 3-4 weeks, patient came to the pharmacy complaining about shoulder pain.
Age: 60.0
Sex: M
Vaccine: VARZOS
Symptoms: Dysgeusia, Eating disorder symptom
Clinical narrative: Taste and texture of food is off. 4 days later there is no change.
Age: 3.0
Sex: M
Vaccine: MMR
Symptoms: Eczema, Inflammation, Rash
Clinical narrative: Eczema/rash noticed that morning, got worse over about 3/4 days, staying inflamed now. Same reaction to eating things that contain eggs.
Age: 55.0
Sex: M
Vaccine: FLU4
Symptoms: Arthralgia, Asthenia, Myalgia, Pyrexia
Clinical narrative: Fever 101 degrees F, muscle/joint aches, Advil to help alleviate aching, fever decreased to 9.8F next day, debilitating aches for 2 days.
Age: 1.1
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Autoimmune haemolytic anaemia, Autopsy, Biopsy skin abnormal, Blood test abnormal, Coombs direct test positive
Clinical narrative: Information has been received from the authors in a literature article concerning a patient with VARIVAX (Merck) (manufacturer unknown), M-M-R II and methylprednisolone (manufacturer unknown) therapy. At 13 months of age, a previous healthy girl with RAG2 deficiency presented acutely with fever, jaundice, cough, rhinorrhea, diarrhea and approximately 10 erythematous papules on her torso and extremities. Preliminary studies revealed direct Coombs positive anemia and leukocytosis with granulocytes predominating. Initial treatment measures included blood transfusions, intravenous immunoglobulin (MG) and high dose methylprednisolone (manufacturer unknown) (up to 80 mg/day), leading to transient resolution of hemolysis. In addition, she developed autoimmune thrombocytopenia (nadir 25,000 platelets/1/4.L). Three weeks after onset of illness, her rash evolved into discrete 3-mm eschars; however, very few, if any new skin lesions developed. Skin biopsy revealed intranuclear inclusion bodies typical of Herpesviridae and intravenous acyclovir was initiated. Despite antiviral therapy, which later included foscarnet, her clinical status deteriorated over subsequent weeks. Obtundation ensued, and the patient died due to complications of hepatic and renal failure, disseminated intravascular coagulation and recalcitrant autoimmune hemolytic anemia. Three weeks before onset of illness, the patient received her first VARIVAX (Merck) (manufacturer unknown) (dose and route unknown), MMR (manufacturer unknown) (dose and route unknown) and hepatitis A (manufacturer unknown). There was no obvious contraindication to the administration of live virus vaccination. She had previously received all vaccinations as per the Advisory Committee on Immunization Practices (ACIP) recommended schedule, including the rotavirus series, which were well tolerated. Prior to death, vaccine strain varicella zoster virus (VZV) was detected in her cerebrospinal fluid (723 copies/mL), skin (137,156 copies/mL) and esophagus by PCR assays and immunohistochemistry staining, respectively. Throat swabs, also obtained prior to death, detected mumps and rubella by PCR assays. Stool samples submitted for viral electron microscopy were negative, including assessment for rotavirus. Ophthalmic examination revealed corneal dendrites with typical features of VZV infection. Autopsy demonstrated VZV dissemination in the lungs and liver as well as profound lymphoid depletion of lymph nodes and thymic tissue. VZV, mumps and rubella isolated from the patient were confined as vaccine genotypes Oka, Jeryl-Lynn and RA 27/3, respectively. The reporter considered the events to be related to VARIVAX (Merck)(manufacturer unknown), MMR (manufacturer unknown), methylprednisolone (manufacturer unknown) and hepatitis A (manufacturer unknown). Upon internal review, renal failure, hepatic failure and disseminated intravascular coagulation were considered to be medically significant. Additional information has been requested.
Age: 1.1
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Coombs positive haemolytic anaemia, Cough, Death, Depressed level of consciousness, Diarrhoea
Clinical narrative: Information has been received from the authors in a literature article concerning a patient with VARIVAX (Merck) (manufacturer unknown), M-M-R II and methylprednisolone (manufacturer unknown) therapy. At 13 months of age, a previous healthy girl with RAG2 deficiency presented acutely with fever, jaundice, cough, rhinorrhea, diarrhea and approximately 10 erythematous papules on her torso and extremities. Preliminary studies revealed direct Coombs positive anemia and leukocytosis with granulocytes predominating. Initial treatment measures included blood transfusions, intravenous immunoglobulin (MG) and high dose methylprednisolone (manufacturer unknown) (up to 80 mg/day), leading to transient resolution of hemolysis. In addition, she developed autoimmune thrombocytopenia (nadir 25,000 platelets/1/4.L). Three weeks after onset of illness, her rash evolved into discrete 3-mm eschars; however, very few, if any new skin lesions developed. Skin biopsy revealed intranuclear inclusion bodies typical of Herpesviridae and intravenous acyclovir was initiated. Despite antiviral therapy, which later included foscarnet, her clinical status deteriorated over subsequent weeks. Obtundation ensued, and the patient died due to complications of hepatic and renal failure, disseminated intravascular coagulation and recalcitrant autoimmune hemolytic anemia. Three weeks before onset of illness, the patient received her first VARIVAX (Merck) (manufacturer unknown) (dose and route unknown), MMR (manufacturer unknown) (dose and route unknown) and hepatitis A (manufacturer unknown). There was no obvious contraindication to the administration of live virus vaccination. She had previously received all vaccinations as per the Advisory Committee on Immunization Practices (ACIP) recommended schedule, including the rotavirus series, which were well tolerated. Prior to death, vaccine strain varicella zoster virus (VZV) was detected in her cerebrospinal fluid (723 copies/mL), skin (137,156 copies/mL) and esophagus by PCR assays and immunohistochemistry staining, respectively. Throat swabs, also obtained prior to death, detected mumps and rubella by PCR assays. Stool samples submitted for viral electron microscopy were negative, including assessment for rotavirus. Ophthalmic examination revealed corneal dendrites with typical features of VZV infection. Autopsy demonstrated VZV dissemination in the lungs and liver as well as profound lymphoid depletion of lymph nodes and thymic tissue. VZV, mumps and rubella isolated from the patient were confined as vaccine genotypes Oka, Jeryl-Lynn and RA 27/3, respectively. The reporter considered the events to be related to VARIVAX (Merck)(manufacturer unknown), MMR (manufacturer unknown), methylprednisolone (manufacturer unknown) and hepatitis A (manufacturer unknown). Upon internal review, renal failure, hepatic failure and disseminated intravascular coagulation were considered to be medically significant. Additional information has been requested.
Age: 1.1
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Immune thrombocytopenic purpura, Immunoglobulin therapy, Immunohistochemistry, Jaundice, Leukocytosis
Clinical narrative: Information has been received from the authors in a literature article concerning a patient with VARIVAX (Merck) (manufacturer unknown), M-M-R II and methylprednisolone (manufacturer unknown) therapy. At 13 months of age, a previous healthy girl with RAG2 deficiency presented acutely with fever, jaundice, cough, rhinorrhea, diarrhea and approximately 10 erythematous papules on her torso and extremities. Preliminary studies revealed direct Coombs positive anemia and leukocytosis with granulocytes predominating. Initial treatment measures included blood transfusions, intravenous immunoglobulin (MG) and high dose methylprednisolone (manufacturer unknown) (up to 80 mg/day), leading to transient resolution of hemolysis. In addition, she developed autoimmune thrombocytopenia (nadir 25,000 platelets/1/4.L). Three weeks after onset of illness, her rash evolved into discrete 3-mm eschars; however, very few, if any new skin lesions developed. Skin biopsy revealed intranuclear inclusion bodies typical of Herpesviridae and intravenous acyclovir was initiated. Despite antiviral therapy, which later included foscarnet, her clinical status deteriorated over subsequent weeks. Obtundation ensued, and the patient died due to complications of hepatic and renal failure, disseminated intravascular coagulation and recalcitrant autoimmune hemolytic anemia. Three weeks before onset of illness, the patient received her first VARIVAX (Merck) (manufacturer unknown) (dose and route unknown), MMR (manufacturer unknown) (dose and route unknown) and hepatitis A (manufacturer unknown). There was no obvious contraindication to the administration of live virus vaccination. She had previously received all vaccinations as per the Advisory Committee on Immunization Practices (ACIP) recommended schedule, including the rotavirus series, which were well tolerated. Prior to death, vaccine strain varicella zoster virus (VZV) was detected in her cerebrospinal fluid (723 copies/mL), skin (137,156 copies/mL) and esophagus by PCR assays and immunohistochemistry staining, respectively. Throat swabs, also obtained prior to death, detected mumps and rubella by PCR assays. Stool samples submitted for viral electron microscopy were negative, including assessment for rotavirus. Ophthalmic examination revealed corneal dendrites with typical features of VZV infection. Autopsy demonstrated VZV dissemination in the lungs and liver as well as profound lymphoid depletion of lymph nodes and thymic tissue. VZV, mumps and rubella isolated from the patient were confined as vaccine genotypes Oka, Jeryl-Lynn and RA 27/3, respectively. The reporter considered the events to be related to VARIVAX (Merck)(manufacturer unknown), MMR (manufacturer unknown), methylprednisolone (manufacturer unknown) and hepatitis A (manufacturer unknown). Upon internal review, renal failure, hepatic failure and disseminated intravascular coagulation were considered to be medically significant. Additional information has been requested.
Age: 1.1
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Platelet count decreased, Polymerase chain reaction positive, Pyrexia, Rash, Rash papular
Clinical narrative: Information has been received from the authors in a literature article concerning a patient with VARIVAX (Merck) (manufacturer unknown), M-M-R II and methylprednisolone (manufacturer unknown) therapy. At 13 months of age, a previous healthy girl with RAG2 deficiency presented acutely with fever, jaundice, cough, rhinorrhea, diarrhea and approximately 10 erythematous papules on her torso and extremities. Preliminary studies revealed direct Coombs positive anemia and leukocytosis with granulocytes predominating. Initial treatment measures included blood transfusions, intravenous immunoglobulin (MG) and high dose methylprednisolone (manufacturer unknown) (up to 80 mg/day), leading to transient resolution of hemolysis. In addition, she developed autoimmune thrombocytopenia (nadir 25,000 platelets/1/4.L). Three weeks after onset of illness, her rash evolved into discrete 3-mm eschars; however, very few, if any new skin lesions developed. Skin biopsy revealed intranuclear inclusion bodies typical of Herpesviridae and intravenous acyclovir was initiated. Despite antiviral therapy, which later included foscarnet, her clinical status deteriorated over subsequent weeks. Obtundation ensued, and the patient died due to complications of hepatic and renal failure, disseminated intravascular coagulation and recalcitrant autoimmune hemolytic anemia. Three weeks before onset of illness, the patient received her first VARIVAX (Merck) (manufacturer unknown) (dose and route unknown), MMR (manufacturer unknown) (dose and route unknown) and hepatitis A (manufacturer unknown). There was no obvious contraindication to the administration of live virus vaccination. She had previously received all vaccinations as per the Advisory Committee on Immunization Practices (ACIP) recommended schedule, including the rotavirus series, which were well tolerated. Prior to death, vaccine strain varicella zoster virus (VZV) was detected in her cerebrospinal fluid (723 copies/mL), skin (137,156 copies/mL) and esophagus by PCR assays and immunohistochemistry staining, respectively. Throat swabs, also obtained prior to death, detected mumps and rubella by PCR assays. Stool samples submitted for viral electron microscopy were negative, including assessment for rotavirus. Ophthalmic examination revealed corneal dendrites with typical features of VZV infection. Autopsy demonstrated VZV dissemination in the lungs and liver as well as profound lymphoid depletion of lymph nodes and thymic tissue. VZV, mumps and rubella isolated from the patient were confined as vaccine genotypes Oka, Jeryl-Lynn and RA 27/3, respectively. The reporter considered the events to be related to VARIVAX (Merck)(manufacturer unknown), MMR (manufacturer unknown), methylprednisolone (manufacturer unknown) and hepatitis A (manufacturer unknown). Upon internal review, renal failure, hepatic failure and disseminated intravascular coagulation were considered to be medically significant. Additional information has been requested.