chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 62.0
Sex: F
Vaccine: HEP
Symptoms: Abnormal faeces, Arthritis, Dizziness, Headache, Hepatic function abnormal
Clinical narrative: 27Sep89 pt vax 2nd hepta B; exp severe h/a, n/v, chilling, achiness, + low grade fever. 05Oct89 noted arthritis, pain, + stiffness w/ fatigue + cycles of h/a, nausea, chills, and/or too hot, weakness, lightheadedness, + rt upper quad pain.
Age: 62.0
Sex: F
Vaccine: HEP
Symptoms: Myasthenic syndrome, Pain, Pyrexia
Clinical narrative: 27Sep89 pt vax 2nd hepta B; exp severe h/a, n/v, chilling, achiness, + low grade fever. 05Oct89 noted arthritis, pain, + stiffness w/ fatigue + cycles of h/a, nausea, chills, and/or too hot, weakness, lightheadedness, + rt upper quad pain.
Age: 44.0
Sex: F
Vaccine: HEP
Symptoms: Convulsion, Nausea
Clinical narrative: 27Oct89 pt vax w/ hepta B; exp nausea. 06Nov89 had seizure for 15 minutes.
Age: 25.0
Sex: F
Vaccine: HEP
Symptoms: Injection site hypersensitivity, Injection site oedema, Pruritus
Clinical narrative: Pt vax w/ hepta B; devel redness, itching + swelling at inject site for 20 minutes.  MD felt that reaction not related to vax.
Age: 25.0
Sex: F
Vaccine: HEP
Symptoms: Cough, Face oedema, Pruritus, Rash, Vasodilatation
Clinical narrative: 13Nov89 pt vax 2nd hepta B; devel cough, face warm to touch. 14Nov89 pt exp warm feeling in face + itchy feeling in ears + throat, red blotches on face, neck + ears w/ facial flushing + slightly puffy appearance under eyes and lip. see worm
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Atrial fibrillation, Bradycardia, Cardiovascular disorder, Ventricular extrasystoles
Clinical narrative: 27OCT89 pt vax w/hepta B; 01NOV89 felt weak, tired, sick, & had PVC's assoc w/mitral valve prolapse.  Sx reoccurred after 2nd vax.  Tx w/cardiac meds for PVC's atrial fibrillation & bradycardia. See worm...
Age: 29.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Cystitis, Pyrexia, Sinusitis, Urinary tract infection
Clinical narrative: 30Oct89 pt vax w/ hepta B; 14Nov89 exp right flank + abdo pain tx unsucc. w/ heat + Motrin, devel cystitis + low grade fever.  CBC + urinalysis revealed urinary tract infection.  Urine culture was positive for yeast. Tx w/ Cipro. See worm..
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Oedema, Pain
Clinical narrative: 23OCT89 pt vax 2nd hepta B; devel local edema & swelling w/pain from shoulder to fingertips & marked swelling at inject site.  Right arm painful for 10 days.
Age: 21.0
Sex: F
Vaccine: HEP
Symptoms: Chills, Injection site oedema, Injection site pain, Vasodilatation
Clinical narrative: 14Nov89 pt vax w/ hepta B; devel chills, w/ pain + swelling in deltoid area of left arm which was warm to touch.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Arthritis
Clinical narrative: Pt vax w/ 2nd hepta B; One month later devel bilateral capsulitis.  Tx w/ anti-inflammatory therapy, possibly Voltaren.  MD felt that reaction was due to profession not vax.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Dyspnoea, Hypertonia, Nausea, Paraesthesia
Clinical narrative: 23OCT89 pt vax w/hepta B; devel numbness that shot down arm into fingertips, numbness & tightness in neck muscles & tingling in left cheek & right hand, shortness of breath.  Pt felt unwell for 3 days w/ nausea.
Age: 27.0
Sex: F
Vaccine: HEP
Symptoms: Face oedema, Pruritus, Rash
Clinical narrative: 03nov89 pt vax w/ hepta B; 10Nov89 pt awoke w/ swelling + itching of eyes + face, rash on arms + back.  Seen in ER + tx w/ Benadryl w/o relief of itching.  Tx w/ Periactin + pruritus resolved.  Rash resolved but skin remained sensitive.
Age: 43.0
Sex: M
Vaccine: HEP
Symptoms: Ageusia, Arthralgia, Aspartate aminotransferase increased, Asthenia, Hyperhidrosis
Clinical narrative: 07SEP89 pt vax w/hepta B; devel flu-like sx w/n/v, weakness, sweats & loss of taste.  21OCT89 vax 2nd hepta B & sx reoccurred.  01NOV89 devel elevated SGOT, arthralgia, & myalgia. Tx w/Compazine.
Age: 43.0
Sex: M
Vaccine: HEP
Symptoms: Influenza, Myalgia, Vomiting
Clinical narrative: 07SEP89 pt vax w/hepta B; devel flu-like sx w/n/v, weakness, sweats & loss of taste.  21OCT89 vax 2nd hepta B & sx reoccurred.  01NOV89 devel elevated SGOT, arthralgia, & myalgia. Tx w/Compazine.
Age: 49.0
Sex: F
Vaccine: HEP
Symptoms: Diarrhoea, Myasthenic syndrome, Somnolence
Clinical narrative: Pt recvd 2nd vax 28JUN89 & later exp diarrhea,lethargy & muscle weakness. Pt recovered spontaneously.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Rash
Clinical narrative: pt recvd 2nd dose of Hep B vax 06JUL89, & on 13JUL89 devel profuse pruritic rash on face & trunk p/ doing yard work. Tx w/ hydrocortisone & terfenadine.
Age: 32.0
Sex: M
Vaccine: HEP
Symptoms: Pruritus, Urticaria
Clinical narrative: Pt recvd 2nd vax of Hep B & later exp itching w/ hives under arms & down sides.Pt tx w/ meds & sx abated slightly,w/ recurrences of hives & itching.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Pain, Paraesthesia
Clinical narrative: pt recvd 2nd Hep B vax 29NOV89 & later exp pain radiating down arm to the wrist,& under the arm to shoulder & neck.By 04DEC89 pt had marked improvement w/ slight tingling in left hand. 22JAN90 pt. recovered.
Age: 25.0
Sex: F
Vaccine: HEP
Symptoms: Facial palsy
Clinical narrative: Pt recvd 1st dose of Hep B vax & later devel Bell's Palsy. Tx w/unspecified steroids.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Hypoglycaemia, Lymphadenopathy, Malaise, Nausea
Clinical narrative: W/in 12 hrs following vax pt developed n. 7Jan89 developed a T lasted approx 5 days. 8Jan89 developed enlarged & painful axillary lymph nodes. For next several mo exp lethargy & malaise. Exp episodes of hypoglycemia. 14Feb90 sxs persisted.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Pain, Pyrexia
Clinical narrative: W/in 12 hrs following vax pt developed n. 7Jan89 developed a T lasted approx 5 days. 8Jan89 developed enlarged & painful axillary lymph nodes. For next several mo exp lethargy & malaise. Exp episodes of hypoglycemia. 14Feb90 sxs persisted.
Age: 22.0
Sex: F
Vaccine: HEP
Symptoms: Dyspnoea, Pruritus
Clinical narrative: Pt recvd 1st dose of Hep B vax 01NOV89 & 02NOV89 devel generalized pruritus & mild shortness of breath w/o wheezing. Sx resolved spontaneously by next day.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Headache, Hypertension, Somnolence, Tachycardia
Clinical narrative: Pt recvd 3rd dose of Hep B vax 01DEC89 & devel tachycardia,elevated BP(130/70),tremors,h/a,weakness,sleepiness,& warm feeling @ inject site.Tx w/ astemizole(Hismanal).
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Tremor, Vasodilatation
Clinical narrative: Pt recvd 3rd dose of Hep B vax 01DEC89 & devel tachycardia,elevated BP(130/70),tremors,h/a,weakness,sleepiness,& warm feeling @ inject site.Tx w/ astemizole(Hismanal).
Age: 30.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Lymphadenopathy
Clinical narrative: Pt recvd 1st vax of Hep B vax 11APR89 & devel swelling & soreness of axillary nodes,which resolved p/ 1-2 days.On 07JUN89 pt recvd 2nd vax & devel swelling & soreness of axillary nodes w/ generalized weakness.Sx resolved p/ 2-3 days.
Age: 48.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Asthenia
Clinical narrative: Pt recvd 1st dose of Hep B vax 28NOV89 & exp fatigue & awakened in  morning w/ disseminated arthralgias. Pt recovered after 1 week.
Age: 50.0
Sex: F
Vaccine: HEP
Symptoms: Injection site hypersensitivity, Injection site pain, Nausea, Rash, Somnolence
Clinical narrative: Pt recvd 1st,2nd,& 3rd vax 16MAY89,28JUN89 & 07DEC89, resp. 08DEC89 pt exp soreness w/ redness & heat @ inject site & felt tired. pt exp nausea,vomiting & butterfly rash of purpuric spots on nose,cheeks w/ red patches under eyes
Age: 50.0
Sex: F
Vaccine: HEP
Symptoms: Vasodilatation, Vomiting
Clinical narrative: Pt recvd 1st,2nd,& 3rd vax 16MAY89,28JUN89 & 07DEC89, resp. 08DEC89 pt exp soreness w/ redness & heat @ inject site & felt tired. pt exp nausea,vomiting & butterfly rash of purpuric spots on nose,cheeks w/ red patches under eyes
Age: 50.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Laboratory test abnormal, Pain
Clinical narrative: Pt recvd 1st dose of Hep B vax 03OCT89 & later devel bilateral diffuse hand pain,which was worse @ night.P/ 2nd vax 16NOV89 joint pain worsened.Tx w/ ibuprofen & naproxen.
Age: 27.0
Sex: F
Vaccine: HEP
Symptoms: Headache
Clinical narrative: Pt recvd 1st dose of Hep B vax 01NOV89 & devel migraine h/a.Tx w/ unspecified Rx med.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Arrhythmia, Dizziness, Headache, Hypertension, Syncope
Clinical narrative: Pt recvd 1st dose of Hep B vax 14DEC89 & later exp flushing,lightheadedness,syncope(lasting 45 sec),cardiac dysrhythmia w/ inc BP(160/90).On 15DEC89 pt. complained of h/a.Pt. recvd 2nd vax & exp dizziness.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Vasodilatation
Clinical narrative: Pt recvd 1st dose of Hep B vax 14DEC89 & later exp flushing,lightheadedness,syncope(lasting 45 sec),cardiac dysrhythmia w/ inc BP(160/90).On 15DEC89 pt. complained of h/a.Pt. recvd 2nd vax & exp dizziness.
Age: 24.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Dizziness, Dyspnoea, Pain, Somnolence
Clinical narrative: Pt recvd 1st dose of Hep B vax 03NOV89 & 17NOV89 exp aching of wrists & fingers.04DEC89 recvd 2nd vax & exp dizziness,tiredness & breathlessness. Later pt exp pain in fingers & MD dx temp polyarthritis due to Hep B vax.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Malaise, Somnolence
Clinical narrative: Pt recvd 1st dose of Hep B vax 09NOV89 & later exp malaise & lethargy.24 hrs later sx resolved.Pt recvd 2nd vax 15DEC89 & felt tired & weak.
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Dizziness, Nausea, Vasodilatation
Clinical narrative: Pt recvd 1st dose of Hep B vax 28JUL89 & later exp facial flushing,dizziness,lightheadedness,nausea & fatigue.Sx remitted spontaneously.
Age: 36.0
Sex: M
Vaccine: HEP
Symptoms: Chills, Injection site hypersensitivity, Injection site oedema, Injection site pain, Malaise
Clinical narrative: Pt recvd 1st dose of Hep B vax 18FEB89 & devel fever,chills & malaise for 10 hrs.18JUL89 pt recvd 2nd vax & exp same reaction w/ soreness,redness & localized swelling @ inject site.
Age: 36.0
Sex: M
Vaccine: HEP
Symptoms: Pyrexia
Clinical narrative: Pt recvd 1st dose of Hep B vax 18FEB89 & devel fever,chills & malaise for 10 hrs.18JUL89 pt recvd 2nd vax & exp same reaction w/ soreness,redness & localized swelling @ inject site.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Oedema, Pyrexia, Rash, Vasodilatation
Clinical narrative: Pt recvd 2nd dose of vax 07DEC89 & devel erythema nodosum below left knee w/enlargement & erythema across front & back of left-lower extremity. Left leg was swollen & warm, rt leg had small erythematous patches, arthralgia & t of 100.8.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Asthenia, Chills, Hypoglycaemia, Nausea
Clinical narrative: Pt recvd 1st dose of Hep B vax 06DEC89 & exp nausea,weakness & lethargy.Pt. recvd 2nd vax 05JAN90 & devel chills,upper rt quadrant pain & nausea.05FEB90 devel rash on back w/ Pruritus.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Pruritus, Rash, Somnolence
Clinical narrative: Pt recvd 1st dose of Hep B vax 06DEC89 & exp nausea,weakness & lethargy.Pt. recvd 2nd vax 05JAN90 & devel chills,upper rt quadrant pain & nausea.05FEB90 devel rash on back w/ Pruritus.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Anorexia, Diarrhoea, Nausea
Clinical narrative: Pt recvd 1st dose of Hep B vax 06DEC89 & devel gastrointestinal cramping & diarrhea.Later pt exp nausea & loss of appetite that lasted approx. 3-4 days.
Age: 29.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Anorexia, Diarrhoea, Nausea
Clinical narrative: Pt recvd 1st dose of Hep B vax 06DEC89 & exp gastrointestinal cramps & diarrhea w/ nausea & loss of appetite. Tx w/ Rx meds. Recvd 2nd dose w/ no noted side effects.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Anorexia, Diarrhoea, Dizziness, Nausea
Clinical narrative: Pt recvd 1st dose of Hep B vax 06DEC89 & devel gastrointestinal cramps,diarrhea,nausea,dizziness & was unable to eat.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Alanine aminotransferase increased, Arthritis, Aspartate aminotransferase increased, Asthenia, Pyrexia
Clinical narrative: Pt recvd 1st dose of Hep B vax 13DEC89 &later devel a rash, arthritis, fever & fatigue.On 02JAN90 arthritis persisted & pt. tx w/ ibuprofen. F/U lab tests revealed inc SGOT & SGPT;
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Rash
Clinical narrative: Pt recvd 1st dose of Hep B vax 13DEC89 &later devel a rash, arthritis, fever & fatigue.On 02JAN90 arthritis persisted & pt. tx w/ ibuprofen. F/U lab tests revealed inc SGOT & SGPT;
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain, Pain, Tenosynovitis
Clinical narrative: Pt recvd 2nd dose of Hep B vax 14DEC88 & devel soreness in left shoulder.On 04JUN89 pt recvd 3rd dose of vax & condition worsened.On 21DEC89 pt dx w/ adhesive capsulitis & probable rotator cuff tendinitis w/ secondary shoulder stiffness.
Age: 22.0
Sex: F
Vaccine: HEP
Symptoms: Pruritus, Urticaria
Clinical narrative: Pt recvd 1st dose of Hep B vax 11AUG89 & 0n 20AUG89 devel pruritus w/ urticaria.On 11SEP89 pt recvd 2nd dose & later devel urticaria.Pt tx w/ DPH.
Age: 56.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Chills, Diarrhoea, Hypokinesia, Injection site hypersensitivity
Clinical narrative: Pt recvd series of 3 hep B vax on 0,1,6 mo schedule & later 16JAN91 exp inject site react w/inflammation, swelling, chills, inc pain, diarrhea, cramping, T-100 & aching shoulder w/decreased mobility.
Age: 56.0
Sex: F
Vaccine: HEP
Symptoms: Injection site oedema, Pyrexia, Vasodilatation
Clinical narrative: Pt recvd series of 3 hep B vax on 0,1,6 mo schedule & later 16JAN91 exp inject site react w/inflammation, swelling, chills, inc pain, diarrhea, cramping, T-100 & aching shoulder w/decreased mobility.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Hlth professional reported several problems from this lot number.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 2 pts showed "weakly positive not protected" 3 months p/ the last in a series of 3 vaccines.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 8 pts "did not reach protective titers". Plan to revaccinate.
Age: 26.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd series of 3 hep B vax on 0,1,6 months schedule & failed to respond to normal series of 3.Booster was given.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Ecchymosis, Oedema
Clinical narrative: Pt recvd 1st dose of hep B vax 18JAN91 & devel a "black & blue", swollen arm.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9,from total of 191 pts who completed series of 3 hep B vax & failed to achieve immunity.Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9 from total of 191 pts who completed series of 3 vax & failed to achieve immunity.Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9 from total of 191 pts who completed series of 3 hep B vax & failed to achieve immunity.Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9 from total of 191 pts who completed series of 3 hep B vax, failed to achieve immunity.Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1  of 9 from total from total of 191 who completed series of 3 Hep B vax and failed to achieve immunity. Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9 from total of 191 pts who completed series of 3 Hep B vax and did not achieve immunity.Pt did not seroconvert.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9,from total of 191 pts who completed series of 3 Hep B vax and failed to achieve immunity.Pt did not seroconvert.
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt 1 of 9 from total of 191 pts who completed series of 3 Hep B vax and failed to achieve immunity. Pt did not seroconvert.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Several pts recvd hep B vax w/ inadequate response.
Age: 33.0
Sex: M
Vaccine: HEP
Symptoms: Alanine aminotransferase increased, Hepatic function abnormal, Hepatitis
Clinical narrative: Pt recvd 1st vax of hep B 17NOV89 & exp elevated ALT/AST @ baseline.1st 2 mos of study,pt exp elevated ALT (121-150) & GGT 7FEB90.MD indicated relationship unrelated & review of case indicated chemical hep, B due to HBsAG carriage.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Several pts were weakly positive p/ recving series of 3 hep B vax.Pts seroconverted p/ recving booster vax.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt exp negative lab test p/ 3 dose series of hep B vax.Pt recvd addt'l hep B doses.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Malaise
Clinical narrative: Pt recvd 1st dose of hep B vax 22JAN91 & exp diffuse arthralgia & malaise.Tx w/ meds.MD feels events related to MMR vax & not Hep B vax.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 10 pts did not respond to a series of 3 hep B vax.
Age: 26.0
Sex: F
Vaccine: HEP
Symptoms: Ecchymosis, Injection site pain, Vasodilatation
Clinical narrative: Pt recvd 2nd dose of hep B vax 11JAN91 & exp pain,warmth & black & blue marks @ inject site.
Age: 38.0
Sex: F
Vaccine: HEP
Symptoms: Laboratory test abnormal
Clinical narrative: Pt recvd 2nd dose of hep B vax 10JAN91 & exp elevated ALT.
Age: 44.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain
Clinical narrative: Pt recvd 3rd hep B vac 22OCT90 & exp pain @ inject site which lasted 2 weeks.
Age: 23.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain
Clinical narrative: Pt recvd 1st hep B vax 16APR90 & exp ache & sore inject site.P/ 3rd vax,pt exp pain & aching arm.Tx w/ rubbing alcohol.
Age: 55.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain
Clinical narrative: Pt recvd 1st hep B vax 17APR90 & exp pain @ inject site that burned down to elbow & lasted 2-4 hours.
Age: 30.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain
Clinical narrative: Pt recvd 1st hep B vax 14JUN90 & 2nd 17JUL90; exp aching arm & burning w/ movement.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Injection site pain
Clinical narrative: Pt recvd 2nd hep B vax 06JUN90 & exp pain @ inject site. Tx w/ ADAP.
Sex: F
Vaccine: HEP
Symptoms: Aphasia, Nervousness
Clinical narrative: Pt recvd 1st hep B vax & exp nervousness & aphasia. Tx w/ DPH.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Confusional state, Diarrhoea, Dizziness, Injection site hypersensitivity, Nervousness
Clinical narrative: Pt recvd 1st hep B vax 11JAN91 & exp inject site warm to touch,swollen,red,burning sensation,stiff neck,swollen finger joints,nausea,diarrhea,lightheadedness,flu sx,T-101.4,nervousness & confusion.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Nuchal rigidity, Osteoarthritis, Pyrexia
Clinical narrative: Pt recvd 1st hep B vax 11JAN91 & exp inject site warm to touch,swollen,red,burning sensation,stiff neck,swollen finger joints,nausea,diarrhea,lightheadedness,flu sx,T-101.4,nervousness & confusion.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective, Hypercholesterolaemia
Clinical narrative: 4 pts recvd a series of 3 Hep B vax DEC89-JUL90 from same lot # & failed to attain protective antibody titers(non-response)
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Pruritus, Rash maculo-papular
Clinical narrative: Pt recvd 1st hep B vax 29JAN91 & exp erythematous papulosquamous plaques rash on entire body below neck.Rash itched in spots.
Age: 46.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 1st & 2nd hep B vax 21FEB90 & 14JUL90 & was not immune.Recvd 2 boosters 08OCT90 & 10JAN91 & was still not immune.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 2nd hep B vax 19OCT90.  20DEC90 titer results indicated that pt was not immune to hepatitis B.
Age: 53.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd 3rd hep B vax 13NOV90 & was determined to be not immune to hep B on 10JAN91.
Age: 54.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective, Headache, Hepatic function abnormal, Influenza, Myalgia
Clinical narrative: Pt recvd 2nd Hep B vax 14NOV90 & on 28NOV90 & exp fever,nausea,h/a,aching muscles,flu-like sx.Tx w/ ADAP & phenergan. Later, liver enzymes stabilized & returned to normal.
Age: 54.0
Sex: F
Vaccine: HEP
Symptoms: Nausea, Pyrexia
Clinical narrative: Pt recvd 2nd Hep B vax 14NOV90 & on 28NOV90 & exp fever,nausea,h/a,aching muscles,flu-like sx.Tx w/ ADAP & phenergan. Later, liver enzymes stabilized & returned to normal.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia
Clinical narrative: Pt recvd 2 hep B vax on SEP90 & OCT90 & exp arthritic pain for 3 days.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Asthenia, Drug ineffective, Hepatic function abnormal, Hepatitis
Clinical narrative: Pt recvd 3rd hep B vax & devel hepatitis p/3rd dose given 30APR90 w/Recombivax; Brand(s) used for 1st & 2nd doses unspecified; Hepatitis resolved 02MAY90;
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Infection, Leukocytosis, Pancreatitis
Clinical narrative: Pt recvd 3rd hep B vax & devel hepatitis p/3rd dose given 30APR90 w/Recombivax; Brand(s) used for 1st & 2nd doses unspecified; Hepatitis resolved 02MAY90;
Age: 54.0
Sex: F
Vaccine: HEP
Symptoms: Chills, Diarrhoea, Nausea, Pyrexia, Somnolence
Clinical narrative: Pt recvd 1st hep B vax 22JAN91 & exp fever,nausea,chills & oily looking diarrhea w/goldish streaks(Metallic looking)& lethargy.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Abdominal pain, Asthenia, Dizziness, Gastrointestinal disorder, Nausea
Clinical narrative: Pt recvd 2nd hep B vax & felt dizzy, n/v, & passed out;Later exp weakness,cramping,abdominal pain & inc bowel sounds.Tx w/ meds.Later, pt exp lightheadedness,dizziness & felt faint.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Syncope, Vomiting
Clinical narrative: Pt recvd 2nd hep B vax & felt dizzy, n/v, & passed out;Later exp weakness,cramping,abdominal pain & inc bowel sounds.Tx w/ meds.Later, pt exp lightheadedness,dizziness & felt faint.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 3 hep B vax 11APR90,10MAY90 & 11OCT90 & was negative for hep B virus antibody.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd series of 3 hep B vax & was a non-responder.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd 3rd  Hep B vax 15MAY90 &  had negative antibody serum.4th dose given 06DEC90 & on 03JAN91 was HBsAB positive.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pts did not show antibodies p/ 3 vaccines
Age: 36.0
Sex: M
Vaccine: HEP
Symptoms: Conjunctivitis
Clinical narrative: Pt recvd 1st hep B vax 23JAN91 & exp conjunctivitis of right eye.Tx w/ eye drops.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 11 out of 120 pts recvd Hep B vax & did not respond p/ 3rd dose. 1 pt recvd total of 5 doses & was non-responder.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 11 out of 120 pts recvd at least 3 hep B vax were non-responders.10 pts recvd 3 doses of Engerix-B.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Herpes simplex, Infection
Clinical narrative: Pt recvd 1st hep B vax 28JAN91 & later devel herpes simplex viral infection on nose.Tx w/ Zovirax ointment.
Age: 35.0
Sex: M
Vaccine: HEP
Symptoms: Lymphadenopathy
Clinical narrative: Pt recvd 3rd hep B vax JAN91 & later exp lymphadenopathy.
Age: 27.0
Sex: F
Vaccine: HEP
Symptoms: Hepatitis, Hepatitis B surface antigen
Clinical narrative: Pt recvd 2nd hep B vax 29MAY90.19NOV90 pt exposed to HBsAG via puncture wound & pt found to reactive to HBsAG, HBsAB, & HBcAB.Pt either hep B carrier or had chronic active hepatitis.
Sex: U
Vaccine: HEP
Symptoms: Hepatitis B surface antigen
Clinical narrative: On 19NOV90 7 pts tested positive on a hepatitis profile.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd 3 vaccines within 6 months & did not seroconvert p/ 3 doses. Booster vax given.
Age: 56.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt did not respond p/series of 3 inject of Hep B vax.  3rd vax given 12NOV90; Reported not immune to Hep B.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective, Malaise, Pain, Vasodilatation
Clinical narrative: Pt recvd 1st vax 13DEC90 & devel itching & rash @ inject site.Pt recvd 2nd vax 22JAN91 & exp tenderness @ inject site,pain in left arm & swelling of wrist & later exp pain in shoulder joint & malaise.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Herpes simplex
Clinical narrative: Pt recvd 1st dose of Hep B vax DEC90 & exp herpes simplex.Pt exp herpes simplex p/ 2nd vax.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Antinuclear antibody, Embolism, Neoplasm, Neuropathy, Optic neuritis
Clinical narrative: Pt recvd 3rd dose of Hep B vax & devel optic neuritis.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Optic neuritis retrobulbar, Vasculitis
Clinical narrative: Pt recvd 3rd dose of Hep B vax & devel optic neuritis.
Age: 32.0
Sex: F
Vaccine: HEP
Symptoms: Amnesia, Dizziness, Headache, Nausea, Palpitations
Clinical narrative: Pt recvd 1st dose of Hep B vax 01FEB91 & later exp lightheadedness,dizziness,nausea & tachycardia.
Age: 32.0
Sex: F
Vaccine: HEP
Symptoms: Tachycardia, Vertigo
Clinical narrative: Pt recvd 1st dose of Hep B vax 01FEB91 & later exp lightheadedness,dizziness,nausea & tachycardia.
Age: 43.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 3 vax of Hep B the 3rd of which was Engerix B & tested negative for anti hepatitis B surface antigen
Age: 48.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 4 of 5 Pt recvd 3 hep B vax, the 3rd of which was Engerix B, & tested negative for anti-hepatitis B surface antigen.
Age: 51.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recevd 3 vax, the 3rd of which was Engerix B and tested negative for anti-hepatitis B surface antigen.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt received vax series & post-vax screening failed to devel antibodies
Age: 20.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Influenza, Malaise, Pyrexia
Clinical narrative: Pt recvd 2nd vax 05JUL90 & exp T-102,felt bad,achy & weak.Pt. had viral infect lasted 5 days.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Diarrhoea, Influenza, Pyrexia
Clinical narrative: On 25JUL90 pt recvd vax & later exp diarrhea & T-102 w/ flu-like sx.
Age: 27.0
Sex: M
Vaccine: HEP
Symptoms: Arthropathy, Movement disorder, Pain
Clinical narrative: Pt recvd 2nd vax 11JUN90 in rt shoulder & exp pain & decreased range of motion.MD dx local tissue damage & joint problems.Tx w/ steroids.
Age: 24.0
Sex: F
Vaccine: HEP
Symptoms: Chills, Diarrhoea, Headache, Nausea, Pyrexia
Clinical narrative: Pt recvd 2nd vax & exp diarrhea,chills,h/a,nausea,rash,vomiting & T-102.
Age: 24.0
Sex: F
Vaccine: HEP
Symptoms: Rash, Vomiting
Clinical narrative: Pt recvd 2nd vax & exp diarrhea,chills,h/a,nausea,rash,vomiting & T-102.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 3 doses of hep B vax,recving 3rd vax 08AUG90 & tested negative for HBSAB.
Age: 26.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 3 doses of vax on 20SEP90 & 18OCT90 was determined to have no immunity to hepatitis B.
Age: 23.0
Sex: F
Vaccine: HEP
Symptoms: Oedema peripheral, Pyrexia
Clinical narrative: Pt recvd 1st dose of hep B vax 27JAN91 & devel T-100 & swollen hands.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective, Face oedema, Oedema peripheral
Clinical narrative: Pt recvd 3rd dose 06AUG90 & 1 month later tested negative for hepatitis B antibodies.
Age: 58.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Non-responder p/ 4 doses.
Age: 57.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd series of 3 hep B vax & failed to produce adequate AB titers;
Age: 63.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd. series of 3 vax & failed to respond to the vaccine.
Age: 53.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd series of 3 Hepta B vax.  P/3rd dose on 03May90; pt failed to produce adequate antibody titers.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax 3 hepta B;  3rd dose recv on 04Sep90.  Failed to produce adequate antibody titers.
Age: 59.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt vax w/ 3 hepta B; 3rd dose given on 02May90.  Pt failed to produce adequate antibody titers.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ 3 hepta B,  3rd dose given on 03May90.  Pt failed to produce adequate antibody titers.
Age: 60.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/3 dose hepta B given on 02May90.  Pt failed to produce adequate antibody titers.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ 3 hepta B; 3rd dose given on 02May90.  Pt failed to produce adequate antibody titers.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Headache, Myalgia, Neck pain, Vomiting
Clinical narrative: Pt vax w/ 2nd hepta B on 04Dec90; Later pt exp aching all over, h/a, neck ache. 9 hrs later pt exp vomiting.  Sx resolved w/in 24 hrs.  No 3rd dose given.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Dyspnoea, Rash
Clinical narrative: 17Dec90 pt vax w/ hepta B; exp rash on trunk & became worse.  24 hrs postvax exp shortness of breath.  Seen in ER. Tx w/ epinephrine & benadryl.
Age: 33.0
Sex: F
Vaccine: HEP
Symptoms: Infection, Pyrexia
Clinical narrative: pt vax w/ hepta B on 14Dec90; Later exp fever 102F for half day. MD dx as viral synd not related to vax;
Sex: F
Vaccine: HEP
Symptoms: Chills, Infection, Influenza, Injection site pain, Oedema
Clinical narrative: Pt vax w/ hepta B; exp local inject site muscle soreness, fever 103F.
Sex: F
Vaccine: HEP
Symptoms: Pain, Pyrexia, Rhinitis
Clinical narrative: Pt vax w/ hepta B; exp local inject site muscle soreness, fever 103F.
Age: 38.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 18May90 pt vax w/ 3rd hepta B & failed to produce immune response.
Age: 44.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Injection site mass, Injection site oedema, Injection site pain, Myalgia
Clinical narrative: 30May90 pt vax w/ hepta B; exp some soreness.  Pt vax 2nd dose on 29Jun90; exp slight swelling & knot the size of b-b shot.  04Dec90 recv 3rd vax; right arm was swollen & hot to touch.  Arm became very sore & tender.  See worm...
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Diarrhoea, Dyspepsia, Osteoarthritis
Clinical narrative: 05Nov90 pt vax w/ hepta B; exp transient joint pain. 14Dec90 vax w/ 2nd dose; devel severe joint pain in ankle, knees, hips, rt wrist, thumb.  Tx w/ Ansaid & Cytotec.    See worm...
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Chest pain
Clinical narrative: 05Dec90 pt vax w/ hepta B;  exp tightness in chest that lasted more than 36 hrs. Recovered w/in 36 hrs; no problems w/ 2nd dose.
Age: 26.0
Sex: M
Vaccine: HEP
Symptoms: Myasthenic syndrome
Clinical narrative: 04Feb90 pt vax w/ hepta B;  exp muscle weakness in both legs.  This was a 2nd dose in a series of 3 doses.
Age: 47.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt completed series 3 vax; 4 months later titer was drawn and found to have an inadequate response.  Booster dose given & testing still showed inadequate response.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Myalgia, Pain
Clinical narrative: 09Oct90 pt vax w/ hepta B; exp achiness in shoulder, arm.  Pain persisted in muscle of injected arm. Will not complete vax series.
Sex: M
Vaccine: HEP
Symptoms: Urticaria
Clinical narrative: Pt vax w/ hepta B; exp severe urticaria.  Tx w/ benadryl.  Consulted allergist.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Injection site hypersensitivity, Injection site oedema, Injection site pain, Vasodilatation
Clinical narrative: Pt vax w/ 2nd hep B; exp severe local reaction, swelling of arm. Arm was red, warm & painful. Lasted several days and resolved.  No bronchoconstriction observed.
Age: 53.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt vax w/series of 3 hep B; testing after 3rd dose indicated low titer of Anti-HBs detected.  Immune status questionable.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/series of 3 hep B; 3 months after last vax titer was neg.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 3 Pts each vax w/series of 3 hep B; all had titers of less than 10 p/last inject;
Age: 35.0
Sex: F
Vaccine: HEP
Symptoms: Dysgeusia, Headache, Visual disturbance
Clinical narrative: Pt vax w/ hepta B on 04Dec90; pt exp drawing sensation in right eye, h/a, tightness on scalp, soapy taste in mouth, spots in right eye.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Dizziness, Headache, Pain
Clinical narrative: 09Nov90 Pt vax w/ hepta B; felt high, later h/a, & exp sore arm.
Age: 21.0
Sex: F
Vaccine: HEP
Symptoms: Neck pain, Pain, Paraesthesia
Clinical narrative: Pt vax w/ hepta B; exp pain in arm for 3 months, arm felt numb, couldn't put arm up over head or pain would go through neck.  Tx w/ Advil & heat. Sx did not resolve.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd series of 3 hep B vax on 0-6 months schedule.Pt determined to be non-responder 15DEC90. Given booster dose & now has pos HBSAB;
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd series of 3 hep B vax on 0, 1, 6 months schedule.6 mos dose given 17APR90.Pt did not seroconvert.
Age: 68.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd series of 3 hep B vax on 0,1, 6 mo schedule.6 mo dose given 17APR90.Pt did not seroconvert.
Age: 53.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd 3rd dose hep B vax 08JUN90 & exp negative (anti HBS) 26JUL90 w/ addt'l doses given 03AUG90 & 05SEP90 w/ positive (anti HBS) 01NOV90.
Sex: U
Vaccine: HEP
Symptoms: Endocarditis
Clinical narrative: Pt vax w/ hepta B; exp possible endocarditis.  DX is unconfirmed.
Age: 24.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ 3 hepta B; pt did not respond.  Pt recd 3rd hepta B Nov90.  Booster dose given 07Jan91.
Age: 22.0
Sex: M
Vaccine: HEP
Symptoms: Alanine aminotransferase increased
Clinical narrative: Pt vax w/ hepta B on 18Oct89; 29Nov89 exp increase in ALT.  Listed as mild in severity.  18Apr90 recd last dose.  Investigator feels that reaction was unrelated to vax.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 9 out of 350 employees did not respond following 3 hepta B vax.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Amenorrhoea
Clinical narrative: 20Nov90 pt vax w/ hepta B; Dec90 devel amenorrhea for 2 months. Resumed menses Feb91.
Sex: F
Vaccine: HEP
Symptoms: Hepatic function abnormal
Clinical narrative: 27Sep90 pt vax w/ 2nd hepta B; exp elevated liver enzymes.  Pt is undergoing tests to ascertain cause of elevation.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt had borderline titer following series of 3 hepta B.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 50 out of 100 vax w/ hepta B did not devel antibody titers. RPH reported pts were non-converters after 3 vax.  20 out of 120 had titers tested.  6 - neg, 12 - pos, 2 - unaccounted for.
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 3 pts vax w/ hepta B and are having side effects p/ 1st dose.  Reporter indicated "as far as I know none of the reactions are severe."
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 37 out of 89 pts did not respond to 3 hepta B.  Unsure if pts recd all 3 vax yet.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Drug ineffective, Face oedema, Insomnia, Oedema
Clinical narrative: 27Dec90 pt vax w/ hepta B; 31Dec90 exp arthralgia & swelling of hands & face.  No tx.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Pain
Clinical narrative: 27Dec90 pt vax w/ hepta B; 31Dec90 exp arthralgia & swelling of hands & face.  No tx.
Sex: F
Vaccine: HEP
Symptoms: Headache
Clinical narrative: 2 pts vax w/ hepta B; devel h/a.  No tx given.  Resolved in both pts.
Sex: F
Vaccine: HEP, HEP
Symptoms: Arthralgia, Erythema nodosum
Clinical narrative: Aug90 pt vax w/ 2nd hepta B; devel severe arthralgia.  Tx w/ nsaid, solu-cortef, colchicine.  Skin biopsy indicated erythema nodosum.
Age: 28.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have either insuff. or neg antibody levels during post serology testing of anti-HBs.  (see also EBU910169 - EBU910177).
Age: 63.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have either insuff or neg antibody levels during testing for anti-HBs. (See also EBU910168 - EBU910170 - EBU910177)
Age: 32.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for anti HBs.  (see EBU910168 - EBU910169 - EBU910171 - EBU910177)
Age: 57.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Oct90 10 out of 59 pts were found to have either insuff or neg antibody levels during post serology testing for anti HBs.  (see EBU910168, EBU910170 - EBU910172 - EBU910177)
Age: 25.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during testing for anti- HBS.  (see EBU910168 - EBU910171 - EBU910173 - EBU910177)
Age: 38.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for antiHBs.  (see EBU910168 - EBU910172 - EBU910174 - EBU910177)
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for anti- HBs.  (see EBU910168 - EBU910173 - EBU910175 - EBU910177)
Age: 22.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for anti - HBs.  (see EBU910168 - EBU910174 - EBU910176 - EBU910177)
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In OCt90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for anti HBs.  (see EBU910168 - EBU910175 - EBU910177)
Age: 56.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: In Oct90 10 out of 59 pts were found to have insuff or neg antibody levels during post serology testing for anti HBs. (see EBU910168 - EBU910176)
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Reporter has had 3 cases of non-response following 3 doses of hepta B.
Age: 29.0
Sex: M
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt was a non responder after recv series of 3 hepta B;  given on 24May, 26Jun, 26Nov, 1990.
Sex: U
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 3 Pts vax w/ hepta B & exp events
Age: 60.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ 3 hepta B & did not respond. Given on 2Oct, 2Nov, 2Dec, 1990.
Age: 49.0
Sex: F
Vaccine: HEP
Symptoms: Blood alkaline phosphatase increased, Leukopenia, Oedema peripheral, Pain, Paraesthesia
Clinical narrative: 07Feb91 pt vax w/ hepta B; exp left arm paresthesia which rotated to right arm.  Pt recv CAT scan & MRI test.
Age: 49.0
Sex: F
Vaccine: HEP
Symptoms: Red blood cell sedimentation rate increased
Clinical narrative: 07Feb91 pt vax w/ hepta B; exp left arm paresthesia which rotated to right arm.  Pt recv CAT scan & MRI test.
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Bone pain, Chest pain, Coordination abnormal, Dysphagia
Clinical narrative: 16JAN91 pt vax w/ hepta B; exp trigeminal paresthesia left cheek roof of mouth. Recv CAT scan & MRI.
Sex: F
Vaccine: HEP
Symptoms: Paraesthesia, Speech disorder
Clinical narrative: 16JAN91 pt vax w/ hepta B; exp trigeminal paresthesia left cheek roof of mouth. Recv CAT scan & MRI.
Age: 26.0
Sex: F
Vaccine: HEP
Symptoms: Aspartate aminotransferase increased, Blood lactate dehydrogenase increased, Hepatic function abnormal
Clinical narrative: Pt vax w/ hepta B; exp elevated liver enzymes AST & elevated LDH p/ 2nd dose. Pt undergoing testing for hepatitis.
Age: 23.0
Sex: F
Vaccine: HEP
Symptoms: Mouth ulceration
Clinical narrative: 11Dec90 pt vax w/ hepta B; devel fever blister on mouth.  Went to clinic & was given tx.  Clinic felt that event was not related to vax.
Sex: M
Vaccine: HEP
Symptoms: Abdominal pain, Chills, Dizziness, Headache, Myalgia
Clinical narrative: 16FEB91 pt vax w/ hepta B; 17FEB exp fever & chills.  No tx.
Sex: M
Vaccine: HEP
Symptoms: Nausea, Pyrexia, Urinary tract infection
Clinical narrative: 16FEB91 pt vax w/ hepta B; 17FEB exp fever & chills.  No tx.
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Booster vax w/ hepta B given on 01Dec90; Feb91, titer results borderline.
Age: 85.0
Sex: M
Vaccine: HEP
Symptoms: Cardiac failure, Drug ineffective
Clinical narrative: Pt vax w/ 3 doses hepta B; did not respond. Outcome no sequelae.
Age: 50.0
Sex: M
Vaccine: HEP
Symptoms: Asthenia, Drug ineffective, Nausea
Clinical narrative: 11Oct90 pt vax w/ 3rd hepta B; testing on 25Jan91 indicated that vax did not take.
Age: 22.0
Sex: F
Vaccine: HEP
Symptoms: Angioneurotic oedema, Urticaria
Clinical narrative: Pt vax w/ 1st & 2nd hepta B on 09Oct90 & 09Nov90.  Exp events after 2nd dose.  Events resolved.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Angioneurotic oedema, Urticaria
Clinical narrative: 13Nov90 pt vax w/ 3rd hepta B; exp angioedema, urticaria, & hives on 01Jan91.  Events resolved.
Age: 44.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recv series 3 hepta B on 14Feb, 14Mar, 16Jul, 1990.  15Jan91 tests indicated no seroprotection.
Age: 38.0
Sex: F
Vaccine: HEP, HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ hepta B on 22May90, 13Jul90, 30Nov90.  06Feb91 tested neg for HBSAB.
Age: 39.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt vax w/ hepta B on 02Aug90, 05Sep90, 16Oct90.  Jan 1991 titers - zero.
Age: 34.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 3rd hep B vax recvd 13JUN90 & on 05SEP90 had a neg HBSAB titer. 2 addt'l doses of vax led to a pos HBSAB titer
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: 3rd hep B vax recvd 31AUG90 & on 26OCT90 had a neg HBSAB titer.1 addt'l dose given on 20NOV90.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Several pts did not convert p/ series of 3 hep B vax on 0,1,6 months schedule rather than 0,1,2,6 month schedule recommended for hemodialysis pts.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pts did not seroconvert p/ hep B vax.
Age: 46.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 3 hep B vax as follows:20DEC89,24JAN90,16JUL90.Test results 21AUG90 showed pt did not seroconvert.Addt'l dose given & test results again neg for HBSAB.
Age: 59.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax 19DEC89,23JAN90,02JUL90.Test results 14JUL90 were neg for HBSAB.Addt'l vax given & later test results pos for HBSAB.
Age: 51.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd hep B vax 20DEC89, 24JAN90, 02JUL90. Test results 07AUG90 were neg for HBSAB. Addt'l dose given & test results again were neg.
Age: 55.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd 1st 2 hep B vax w/Recombivax & 3rd dose 06MAR90 w/ Energix-B.Test results 11APR90 neg for HBSAB.Addt'l Energix-B dose given & test results again neg for HBSAB.
Age: 43.0
Sex: F
Vaccine: HEP
Symptoms: Dermatitis bullous, Drug ineffective
Clinical narrative: Pt recvd hep B vax on 19DEC89,19JAN90 & 02JUL90.Fever blisters occurred p/ 2nd vax.14AUG90 test results showed pt did not convert p/ vax.Addt'l dose given;results for HBSAB again neg.
Age: 57.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd hep B vax,1st 2 doses were Recombivax;3rd dose on 21MAR90 was Energix-B.04MAY90 test results were neg for HBSAB.Addt'l Engerix-B dose given;test results again neg for HBSAB.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax on 29NOV89,08JAN90 & 11JUN90.Test results neg for HBSAB.Addt'l dose given 18SEP90 & test results were weakly pos for HBSAB.
Age: 48.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd hep B vax on 22DEC89,29JAN90, & 02JUL90.07AUG90 test results were neg for HBSAB.Addt'l dose of vax given;test results again neg for HBSAB.
Age: 52.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax 19DEC89, 29JAN90, & 02JUL90.Test results 20SEP90 were neg for HBSAB.Addt'l dose given;later test results pos for HBSAB.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd hep B vax; 1st dose was Recombivax; 2nd & 3rd doses were Engerix-B on 18OCT89 & 21MAR90, resp. Test results 31MAY90 neg for HBSAB. Addt'l dose given; later test results again neg for HBSAB.
Age: 58.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax;1st 2 doses were Recombivax;3rd dose was Energix-B.Test results on 19JAN90 & 09AUG90 were weakly pos for HBSAB.Addt'l dose of Engerix-B given 13AUG90 & repeat test was pos for HBSAB.
Age: 41.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax;1st 2 doses were Recombivax;3rd dose 21MAR90 was Engerix-B.Test results 01MAY90 were neg for HBSAB.Addt'l dose of Engerix-B given 27MAY90;test results 12JUN90 were pos for HBSAB.
Age: 31.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt recvd series of 3 Recombivax; test results 30MAY89 neg. for HBSAB.4th dose of Recombivax given;test results 27JUN89 again neg.A 5th dose using Engerix-B given 24JUL90;test remained neg.
Age: 36.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt was a non-responder to a complete series of Engerix-B (3 doses); outcome of 2 addt'l doses of vax is unk.
Age: 46.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt was a non-responder to complete series of Engerix-B given on 26FEB90,29MAR90 & 29AUG90.Outcome of 2 addt'l doses unk.
Age: 42.0
Sex: F
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt was a nonresponder to complete series of Engerix-B given on DEC89, 15JAN90 & 27JUL90. Outcome of 2 addt'l doses unk.
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd hep B vax on 19JAN88,16FEB88 & 16AUG88.Blood work on 14AUG90 showed pt not immune to Hep B. 2nd series of vax started;pt expects to complete those in MAY91.
Age: 29.0
Sex: M
Vaccine: HEP
Symptoms: Headache
Clinical narrative: Pressure h/a top of head 1/2-1 hr p/ inject.Rx w/ advil.Advil given p/ next 2 inject & 2x did not reappear.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd Hep B vax on 25NOV87,23DEC87 & 24JAN88.Titers drawn 4 mo p/ 3rd dose showed no immunity.4th dose given & satisfactory titer achieved.
Age: 36.0
Sex: M
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: Pt recvd Hep B vax on 29SEP87,29OCT87 &29MAR88.Titers drawn p/ 3rd dose showed no immunity;4th dose given & satisfactory titer achieved.
Sex: U
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: 30 pts failed to devel HBSAG (?HBSAB) p/ series of 3 vax.The 1st dose was Recombivax;2nd dose was Recombivax or Engerix-B;3rd dose was Engerix-B.
Age: 38.0
Sex: F
Vaccine: HEP
Symptoms: Anxiety, Arthralgia, Influenza, Injection site reaction, Malaise
Clinical narrative: Pt recvd 2nd hep B vax on 04DEC90 & p/ inject devel flu-like sx,arthralgia,anxiety,nausea,malaise,blister @ inject site.
Age: 38.0
Sex: F
Vaccine: HEP
Symptoms: Nausea
Clinical narrative: Pt recvd 2nd hep B vax on 04DEC90 & p/ inject devel flu-like sx,arthralgia,anxiety,nausea,malaise,blister @ inject site.
Age: 38.0
Sex: M
Vaccine: HEP
Symptoms: Drug ineffective
Clinical narrative: Pt found to be a non-responder p/ 3 doses of vax.4th dose given 30JAN91.