Age: 63.0
Sex: M
Vaccine: COVID19
Symptoms: Adverse event, Ageusia, Arthralgia, Arthritis, Bedridden
Clinical narrative: arthritis; loss of taste; difficulty and focusing his brain/don't feel right; could not get warm; all joints swelled up; couldn't move/could not move right shoulder for a day; side effects/adverse reaction that lasted 10 weeks; diarrhea for 10 days/could not drink enough water; move your eyes and it hurts in the back of your head; continued temperature; every muscle of body hurts/muscle aches; knees were on fire/muscle and joint aches/everything hurts, joint, knees; in bed 2 weeks after each dose; This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (arthritis), AGEUSIA (loss of taste), FEELING ABNORMAL (difficulty and focusing his brain/don't feel right), FEELING COLD (could not get warm) and JOINT SWELLING (all joints swelled up) in a 63-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 018B21A and 024N20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 08-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 05-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In 2021, the patient experienced ARTHRITIS (arthritis), AGEUSIA (loss of taste), FEELING ABNORMAL (difficulty and focusing his brain/don't feel right), FEELING COLD (could not get warm), JOINT SWELLING (all joints swelled up), HYPOKINESIA (couldn't move/could not move right shoulder for a day), ADVERSE EVENT (side effects/adverse reaction that lasted 10 weeks), DIARRHOEA (diarrhea for 10 days/could not drink enough water), HEADACHE (move your eyes and it hurts in the back of your head), PYREXIA (continued temperature), MYALGIA (every muscle of body hurts/muscle aches) and ARTHRALGIA (knees were on fire/muscle and joint aches/everything hurts, joint, knees). On an unknown date, the patient experienced BEDRIDDEN (in bed 2 weeks after each dose). The patient was treated with CORTISONE for Knee pain, at an unspecified dose and frequency. At the time of the report, ARTHRITIS (arthritis), AGEUSIA (loss of taste), FEELING ABNORMAL (difficulty and focusing his brain/don't feel right), FEELING COLD (could not get warm), JOINT SWELLING (all joints swelled up), HYPOKINESIA (couldn't move/could not move right shoulder for a day), HEADACHE (move your eyes and it hurts in the back of your head), PYREXIA (continued temperature), MYALGIA (every muscle of body hurts/muscle aches) and ARTHRALGIA (knees were on fire/muscle and joint aches/everything hurts, joint, knees) outcome was unknown and BEDRIDDEN (in bed 2 weeks after each dose), ADVERSE EVENT (side effects/adverse reaction that lasted 10 weeks) and DIARRHOEA (diarrhea for 10 days/could not drink enough water) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Blood test: nothing was wrong (normal) Nothing was wrong. In 2021, SARS-CoV-2 antibody test: negative (Negative) Negative. On an unknown date, Body temperature: abnormal (abnormal) continued temperature. On an unknown date, Liver function test: nothing was wrong (normal) Nothing was wrong. On an unknown date, SARS-CoV-2 antibody test: negative (Negative) Negative.         No concomitant medications were reported.  It was reported that Patient had COVID-19 symptoms. Patient had been with rheumatologist and could not help. Patient used to be a healthy individual before getting the vaccine. Had a 100% energy and went to the gym. Then had to sleep in the middle of the day to recover energy. Company comment: This Spontaneous case concerns a 63-year-old, male patient, with no reported medical history, who experienced the unexpected, non-serious and AESI of Arthritis and Ageusia, among other non-serious events. The events occurred on an unknown date after receiving the first dose of mRNA-1273 vaccine and it was reported that symptoms persisted until second dose of mRNA-1273 vaccine and continued, exact interval cannot be assessed as events dates are not available. The patient reported he had all COVID symptoms, however, it was reported that he tested negative for COVID-19 twice. He was evaluated by a rheumatologist, who could not help and reported to have received two cortisone injections, into one knee to walk. The rechallenge was not applicable, as events started after receiving the first dose and were not recovered before receiving the second dose of vaccination. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-438752 (Patient Link).; Sender's Comments: This Spontaneous case concerns a 63-year-old, male patient, with no reported medical history, who experienced the unexpected, non-serious and AESI of Arthritis and Ageusia, among other non-serious events. The events occurred on an unknown date after receiving the first dose of mRNA-1273 vaccine and it was reported that symptoms persisted until second dose of mRNA-1273 vaccine and continued, exact interval cannot be assessed as events dates are not available. The patient reported he had all COVID symptoms, however, it was reported that he tested negative for COVID-19 twice. He was evaluated by a rheumatologist, who could not help and reported to have received two cortisone injections, into one knee to walk. The rechallenge was not applicable, as events started after receiving the first dose and were not recovered before receiving the second dose of vaccination. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.