Sex: F
Vaccine: CHOL, HEP, HEPA, TYP
Symptoms: Syncope, Vomiting
Clinical narrative: TOOK AN APPLE JUICE AFTER TAKING VAXCHORA; FAINTED; VOMITED; This spontaneous case report was received from an other healthcare professional (PVX2018-3387) on 07-Dec-2018. The report describes a 20-year-old adult female consumer who fainted and vomited following the intake of Vaxchora (company suspect) (lot no: 7000009 and expiry date: 28-Feb-2019). The consumer also "took an apple juice after taking Vaxchora". The consumer also took Hepatitis A vaccine, Hepatitis B vaccine, and Typhim, (non-company suspect) for immunization.   It was reported that the consumer received several vaccines on 07-Dec-2018 (Hepatitis A, Hepatitis B, Typhim, and Vaxchora). Vaxchora was the last vaccine to be taken. She fainted about 45 minutes after the first vaccine was taken, or about 30 minutes after Vaxchora was taken. As treatment, the nurse gave her water and apple juice and she also shared that, about an hour after administration of Vaxchora, consumer had vomited. Furthermore, the nurse stated that the consumer had vasovagal response in the past with blood draws, but not with vaccines.  The action taken with Vaxchora, Hepatitis A vaccine, Hepatitis B vaccine, and Typhim with respect to the events fainted and vomited was unknown, while with respect to the event "took an apple juice after taking Vaxchora" was not applicable.  The clinical outcome of the events fainted and vomited was resolved, while with respect to the event "took an apple juice after taking Vaxchora" was unknown.  Company's Comment: In this case, it was reported that a 20-year-old female consumer fainted and vomited following the intake of Vaxchora, Hepatitis A vaccine, Hepatitis B vaccine, and Typhim vaccines. There seems to be temporal association between the intake of Vaxchora vaccine and the events. However, fainting episodes/ syncope are common adverse event after the intake of Hepatitis B vaccine, and Typhim vaccines. Also, fainting episodes could cause abdominal distress and can lead to nausea and vomiting as seen in this case. Hence, the causality of the events syncope and vomiting is assessed unlikely with Vaxchora vaccine. The causality of the event " took an apple juice after taking Vaxchora" was considered as not applicable.  On 13NOV2020 an internal review identified an error in the patient age unit. The case was reopened, corrected, and requires resubmission for this reason.; Sender's Comments: Company's Comment: In this case, it was reported that a 20-year-old female consumer fainted and vomited following the intake of Vaxchora, Hepatitis A vaccine, Hepatitis B vaccine, and Typhim vaccines. There seems to be temporal association between the intake of Vaxchora vaccine and the events. However, fainting episodes/ syncope are common adverse event after the intake of Hepatitis B vaccine, and Typhim vaccines. Also, fainting episodes could cause abdominal distress and can lead to nausea and vomiting as seen in this case. Hence, the causality of the events syncope and vomiting is assessed unlikely with Vaxchora vaccine. The causality of the event " took an apple juice after taking Vaxchora" was considered as not applicable.