Age: 81.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: External ear pain, Feeling hot, Grief reaction, Hordeolum, Injection site pain
Clinical narrative: severe pain at the injection site; a sty in her eye; got a blister on her face; she got one on her upper lip; pain that goes up her neck to her earlobe down her arm to her elbow(occured 5 times) and now is feeling pain down her ribcage; feeling hot like a sunburn; broken out; anxiety; grief; she began to itch; became red; This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 81-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included COVID 19 Vaccine (received 1st shot of Covid vaccine on 29th March 2021) and Covid 19 vaccine (received 2nd dose of Covid vaccine on 26th April 2021).   On 8th June 2021 09:00, the patient received the 1st dose of Shingrix (intramuscular). On 8th June 2021, 2 hrs after receiving Shingrix and an unknown time after starting Hydroxyzine, the patient experienced pruritus and erythema. On an unknown date, the patient experienced injection site pain, stye, blister, lip blister, generalized aching, feeling hot, skin breakout, anxiety and grief reaction. The patient was treated with hydroxyzine hydrochloride (Hydroxyzine), steroid shot (nos), naproxen (Aleve), fexofenadine hydrochloride (Allegra), famotidine, ophthalmologicals (nos) (Eye Medication), penicillin, dermatologicals nos (Salve (Nos)) and non-drug therapy (Warm Compress). On an unknown date, the outcome of the injection site pain, lip blister, generalized aching, pruritus, erythema, feeling hot, skin breakout, anxiety and grief reaction were unknown and the outcome of the stye and blister were recovered/resolved.   It was unknown if the reporter considered the injection site pain, stye, blister, lip blister, generalized aching, pruritus, erythema, feeling hot, skin breakout, anxiety and grief reaction to be related to Shingrix.  Additional details were provided as follows: The case was reported by patient herself. The patient had received vaccine through mail order shipment and placed it in refrigerator. The patient took the vaccine with ice packs to her doctor for administration. The patient received Shingrix vaccine on right arm and two hours after she began to itch and became red 3 times that day (described by the patient as like a lobster, beet red, like a sunburn). The patient received treatment at the urgent care for a bad reaction which included a steroid injection. The patient had no fever at appointment but reported feeling hot like a sunburn. The patient broke out 56 time and breakout covers her from scalp to feet. It had been now 11 days since she had a full breakout (all over her body) but still had a breakout on her cheeks and chin area that lasted for 2 hours on September 5th. Patient also reported severe pain at the injection site (right arm) that goes up her neck to her earlobe, down her arm to her elbow (occurred 5 times) and now is feeling pain down her ribcage. The patient took Aleve for this pain. Patient had seen multiple doctors, including an allergist and has been prescribed a variety of medications for this reaction including hydroxyzine, Allegra, and famotidine. The patient recently got blister on her face which resolved, then she got one on her upper lip. The patient also reported a sty in her eye which recovered with eye medication, salve, and penicillin, then started developing a sty in her left eye which was treated with warm compresses. Patient asked to reimbursed for her medical expenses (due to the anxiety and grief she has experienced from dealing with adverse effects of Shingrix). Patient was unable to provide lot/expiration of Shingrix and was not asked for email. The reporter consented to follow up.