Sex: U
Vaccine: VARZOS
Symptoms: Injection site pain, Insomnia, Joint range of motion decreased, Loss of personal independence in daily activities, Neuralgia
Clinical narrative: Losing range of motion,making it hard to do my job; Nerve pain was horrible; I'm on lanican patches. Yo help sleep; making it hard to do my job; Shingrix / on dec 30 2020 / March 9 2021 / diagnosed with shingles / Suspected vaccination failure; Diagnosed with shingles / have had 3 shingle outbreaks; My right arm, where I got my injection starting to hurt / it throb; Hurt / It went up to my shoulder / achie should; This case was reported by a consumer and described the occurrence of suspected vaccination failure in a adult patient who received Herpes zoster (Shingrix) for prophylaxis.   On 30th December 2020, the patient received Shingrix. On 3rd January 2021, 4 days after receiving Shingrix, the patient experienced injection site pain and shoulder pain. On 9th March 2021, the patient experienced vaccination failure (serious criteria GSK medically significant) and shingles. On an unknown date, the patient experienced injected limb mobility decreased, nerve pain, difficulty sleeping and activities of daily living impaired. The patient was treated with steroids nos (Steroid (Not Specified)), oxycodone hydrochloride + paracetamol (Percocet) and pregabalin (Lyrica). On an unknown date, the outcome of the vaccination failure and activities of daily living impaired were unknown and the outcome of the shingles, injection site pain, shoulder pain, injected limb mobility decreased and nerve pain were not recovered/not resolved and the outcome of the difficulty sleeping was recovered/resolved.   It was unknown if the reporter considered the vaccination failure, shingles, injection site pain, shoulder pain, injected limb mobility decreased, nerve pain, difficulty sleeping and activities of daily living impaired to be related to Shingrix.  Additional details were provided as follows: The patient had reported the case for himself/herself. The age at vaccination was not reported. The age group was not reported but was captured as an adult as per vaccine indication.  The patient received vaccine on his/her right arm. The patient's right arm, where he/she got injection starting to hurt, the evening it throb and it went up to his/her shoulder. The patient was now losing range of motion,making it hard to do his/her job. On 9th March 2021, the patient went to the doctor and he/she was put on steroid pills to take for arm. At that time patient was diagnosed with shingles and the nerve pain was horrible. The patient was still dealing with his/her throwing arm and achie shoulder and he/she went and had a CT scan (computerized tomography). The patient also seen a pain doctor and he/she was on lanican patches, which helped sleep. The patient was on Percocet for pain and Lyrica for the nerve pain. In the past 6 weeks from the reporting date patient had 3 shingle outbreaks and he/she asked to help him/her. This case was considered as suspected vaccination failure since the details regarding completion of primary vaccination schedule was unknown at the time of reporting. The consent for follow-up was requested.