Age: 45.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Headache, Hypertension, Insomnia, Laboratory test, Malaise
Clinical narrative: blood pressure was too high; numbness; tingling in my face; After a while I started just not feeling well especially when I went to work; hives; blistered; pain; hair loss; My right arm started swelling up so I went to the doctor; This is a spontaneous report received from a contactable reporter(s) (Other HCP). The reporter is the patient.  A 45 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in deltoid right, administration date 21Oct2021 (Lot number: 320308D) at the age of 45 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "Lupus" (ongoing); "kidney cancer" (ongoing); "Partial surgery (R) Nephrectomy", start date: 2019 (unspecified if ongoing); "HTN" (ongoing); "GERD" (ongoing); "Constip." (ongoing); "Stool softener" (ongoing). Concomitant medication(s) included: HCTZ taken for hypertension (ongoing); K-LOR taken for hypertension (ongoing); PROTONIX [OMEPRAZOLE] taken for gastrooesophageal reflux disease (ongoing); COLACE taken for constipation, faeces hard (ongoing). Vaccination history included: Bnt162b2 (Dose: 1st, Anatomical site of injection: R Deltoid, Route of administration: Intramuscular, Batch/lot number: FF2589), administration date: 23Sep2021, when the patient was 45 years old, for Covid-19 Immunization, reaction(s): "light headache", "felt like I was gonna collapse", "I was very shaky". The following information was reported: HYPERTENSION (non-serious), outcome "recovered with sequelae", described as "blood pressure was too high"; HYPOAESTHESIA (non-serious), outcome "recovered with sequelae", described as "numbness"; PARAESTHESIA (non-serious), outcome "recovered with sequelae", described as "tingling in my face"; MALAISE (non-serious), outcome "recovered with sequelae", described as "After a while I started just not feeling well especially when I went to work"; URTICARIA (non-serious), outcome "recovered with sequelae", described as "hives"; BLISTER (non-serious), outcome "recovered with sequelae", described as "blistered"; PAIN (non-serious), outcome "recovered with sequelae", described as "pain"; ALOPECIA (non-serious), outcome "recovered with sequelae", described as "hair loss"; PERIPHERAL SWELLING (non-serious), outcome "recovered with sequelae", described as "My right arm started swelling up so I went to the doctor". The events "blood pressure was too high", "numbness", "tingling in my face", "after a while i started just not feeling well especially when i went to work", "hives", "blistered", "pain", "hair loss" and "my right arm started swelling up so i went to the doctor" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of hypertension, hypoaesthesia, paraesthesia, malaise, urticaria, blister, pain, alopecia, peripheral swelling.   Additional information: Patient didn't had prior vaccination within 4 weeks. After 1st dose of covid-19 Pfizer vaccine I was light headache so I reported this when I went for my 2nd dose. So I was told to take Tylenol and drink plenty of fluids. 1 and 1/2 hour after leaving the pharmacy I felt like I was gonna collapse so I ran home and took some Benadryl. I was very shaky. I've tried to bed as, I was off from work. I kept taking the Benadryl and going to sleep because I wouldn't have that feeling of my body being overwhelmed. I had a routine visit with one of my doctors but she kept telling my blood pressure was too high and gave me blood pressure medications. I tried telling her my body was overeating to the vaccine but she said I was just complaining. I tried the blood pressure medications but started having numbness and tingling in my face. So I discontinued the medications and continue taking Benadryl. After a while I started just not feeling well especially when I went to work, I started with hives, blistered and pain and increased hair loss. My right arm started swelling up so I went to the doctor. The swelling disappeared then returned about 3-4 days later. I went to urgent care where I got steroids and to continue antihistamine until seen by Rheumatologist. I returned home for PCP for follow up visit - (name withheld) RN. Autopsy information: NA  No follow-up attempts are possible. No further information is expected. Sender's Comments: Based on the available information, there is a reasonable possibility of a causal relationship between the suspect vaccine BNT162B2 (COMIRNATY) and reported events which cannot be fully assessed/excluded. The case will be reassessed if additional information becomes available. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.