chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 32.0
Sex: M
Vaccine: FLU3
Symptoms: Nerve injury, Paraesthesia
Clinical narrative: 12/17/2005 1st signs of nerve damage, 12/19/05 Dr visit no diagnosis, 12/21/05 Dr visit referred to neurologist, 12/22/05 Neurologist diagnosed GBS, 12/23/05 EMG Spinal Tap confirmed Guillain Barre Syndrome, 01/24/06 partially recovered. Information from medical records includes paresthesis, decreased reflexes, ataxia. msv
Age: 1.3
Sex: M
Vaccine: DTAP
Symptoms: Abnormal behaviour, Agitation, Anger, Anxiety, Crying
Clinical narrative: Child already showing symptoms after 11/15/2002 vaccines. After #4 DTaP on 2/25/2003 Child worsened. He became irritable, excitability, outbursts of temper, shyness, avoidance, anxiety, tensions, depression in all areas, no focus or contact at all, uncontrollable crying and fidgeting and hyperactive and biting and pinching.
Age: 1.3
Sex: M
Vaccine: DTAP
Symptoms: Depression, Emotional disorder, Excitability, Irritability, Psychomotor hyperactivity
Clinical narrative: Child already showing symptoms after 11/15/2002 vaccines. After #4 DTaP on 2/25/2003 Child worsened. He became irritable, excitability, outbursts of temper, shyness, avoidance, anxiety, tensions, depression in all areas, no focus or contact at all, uncontrollable crying and fidgeting and hyperactive and biting and pinching.
Age: 1.3
Sex: M
Vaccine: DTAP
Symptoms: Social avoidant behaviour, Staring, Tension
Clinical narrative: Child already showing symptoms after 11/15/2002 vaccines. After #4 DTaP on 2/25/2003 Child worsened. He became irritable, excitability, outbursts of temper, shyness, avoidance, anxiety, tensions, depression in all areas, no focus or contact at all, uncontrollable crying and fidgeting and hyperactive and biting and pinching.
Age: 57.0
Sex: F
Vaccine: FLU3
Symptoms: Panniculitis, Skin necrosis, Toxic epidermal necrolysis
Clinical narrative: Flu shot caused a local panniculitis that lasted more than 1 year and required surgical excision of inflamed necrotic fat to finally cure.
Age: 28.0
Sex: U
Vaccine: ANTH, HEP, HEPA, ANTH, HEP, HEPA
Symptoms: Arthralgia, Depression, Dermatitis, Dry skin, Erythema
Clinical narrative: Description: Service member complained of pain (3/10) in right hip 24 hours after receiving anthrax #4, Hep A #2 and Hep B#3 injections and dry, itchy rash with peeling of skin on left index, right ring fingers and right thumb within 2-3 weeks of immunizations.  Also reports local pain at site (8-9/10) and redness for first 3 days post shots, new onset arthralgias (left shoulder, left knee), change in keloid size on anterior chest, blurred vision, tinnitus, sleep problems and depression. Symptom: joint pain isolated start: 9/3/2004 Comment: Moderate pain right hip that caused limping; Symptom: Erythema Start: 9/3/2004 End: 9/6/2004 Comment: Left arm; Symptom: Pain Start:9/3/2004 End: 9/6/2004 Comment: At site; Symptom: Dermatitis, focal Start:9/16/2004 Comment: itchy, peeling rash left index finger and right thumb.
Age: 28.0
Sex: U
Vaccine: ANTH, HEP, HEPA, ANTH, HEP, HEPA
Symptoms: Gait disturbance, Injection site pain, Insomnia, Joint effusion, Keloid scar
Clinical narrative: Description: Service member complained of pain (3/10) in right hip 24 hours after receiving anthrax #4, Hep A #2 and Hep B#3 injections and dry, itchy rash with peeling of skin on left index, right ring fingers and right thumb within 2-3 weeks of immunizations.  Also reports local pain at site (8-9/10) and redness for first 3 days post shots, new onset arthralgias (left shoulder, left knee), change in keloid size on anterior chest, blurred vision, tinnitus, sleep problems and depression. Symptom: joint pain isolated start: 9/3/2004 Comment: Moderate pain right hip that caused limping; Symptom: Erythema Start: 9/3/2004 End: 9/6/2004 Comment: Left arm; Symptom: Pain Start:9/3/2004 End: 9/6/2004 Comment: At site; Symptom: Dermatitis, focal Start:9/16/2004 Comment: itchy, peeling rash left index finger and right thumb.
Age: 28.0
Sex: U
Vaccine: ANTH, HEP, HEPA, ANTH, HEP, HEPA
Symptoms: Pruritus, Rash, Tinnitus, Vision blurred
Clinical narrative: Description: Service member complained of pain (3/10) in right hip 24 hours after receiving anthrax #4, Hep A #2 and Hep B#3 injections and dry, itchy rash with peeling of skin on left index, right ring fingers and right thumb within 2-3 weeks of immunizations.  Also reports local pain at site (8-9/10) and redness for first 3 days post shots, new onset arthralgias (left shoulder, left knee), change in keloid size on anterior chest, blurred vision, tinnitus, sleep problems and depression. Symptom: joint pain isolated start: 9/3/2004 Comment: Moderate pain right hip that caused limping; Symptom: Erythema Start: 9/3/2004 End: 9/6/2004 Comment: Left arm; Symptom: Pain Start:9/3/2004 End: 9/6/2004 Comment: At site; Symptom: Dermatitis, focal Start:9/16/2004 Comment: itchy, peeling rash left index finger and right thumb.
Age: 28.0
Sex: U
Vaccine: ANTH, HEP, HEPA, ANTH, HEP, HEPA
Symptoms: Arthralgia, Discomfort, Nail disorder, Rash
Clinical narrative: Description: Service member complained of pain (3/10) in right hip 24 hours after receiving anthrax #4, Hep A #2 and Hep B#3 injections and dry, itchy rash with peeling of skin on left index, right ring fingers and right thumb within 2-3 weeks of immunizations.  Also reports local pain at site (8-9/10) and redness for first 3 days post shots, new onset arthralgias (left shoulder, left knee), change in keloid size on anterior chest, blurred vision, tinnitus, sleep problems and depression. Symptom: joint pain isolated start: 9/3/2004 Comment: Moderate pain right hip that caused limping; Symptom: Erythema Start: 9/3/2004 End: 9/6/2004 Comment: Left arm; Symptom: Pain Start:9/3/2004 End: 9/6/2004 Comment: At site; Symptom: Dermatitis, focal Start:9/16/2004 Comment: itchy, peeling rash left index finger and right thumb.
Age: 33.0
Sex: M
Vaccine: ANTH
Symptoms: Amnesia, Arthralgia, Diarrhoea, Dizziness, Fatigue
Clinical narrative: bSymptom: Dizziness Comment: +/- accompanied pt. nausea, memory loss (short term), fever-intermittent fevers as high as 103, fatigue>60days, Lymphadenopathy, anterior cervical chain-intermittent swelling of nodes in neck, under the arms, groin, etc; sometimes tender, Pain-sharp localized stabbing pain, shooting: intermittent in arms,legs, neck, etc., Abdominal Pain-intermittent, also c/o bloating and diarrhea, fasciculation, Joint pain, multiple joints, muscle pain, cognitive deficiency, tremors, diarrhea, intermittent-see clinical summary for details.
Age: 33.0
Sex: M
Vaccine: ANTH
Symptoms: Laboratory test abnormal, Lymphadenopathy, Nausea, Pain, Pyrexia
Clinical narrative: bSymptom: Dizziness Comment: +/- accompanied pt. nausea, memory loss (short term), fever-intermittent fevers as high as 103, fatigue>60days, Lymphadenopathy, anterior cervical chain-intermittent swelling of nodes in neck, under the arms, groin, etc; sometimes tender, Pain-sharp localized stabbing pain, shooting: intermittent in arms,legs, neck, etc., Abdominal Pain-intermittent, also c/o bloating and diarrhea, fasciculation, Joint pain, multiple joints, muscle pain, cognitive deficiency, tremors, diarrhea, intermittent-see clinical summary for details.
Age: 33.0
Sex: M
Vaccine: ANTH
Symptoms: Swelling, Tenderness, Tremor
Clinical narrative: bSymptom: Dizziness Comment: +/- accompanied pt. nausea, memory loss (short term), fever-intermittent fevers as high as 103, fatigue>60days, Lymphadenopathy, anterior cervical chain-intermittent swelling of nodes in neck, under the arms, groin, etc; sometimes tender, Pain-sharp localized stabbing pain, shooting: intermittent in arms,legs, neck, etc., Abdominal Pain-intermittent, also c/o bloating and diarrhea, fasciculation, Joint pain, multiple joints, muscle pain, cognitive deficiency, tremors, diarrhea, intermittent-see clinical summary for details.
Age: 68.0
Sex: F
Vaccine: PPV
Symptoms: Feeling hot, Injection site erythema, Injection site swelling, Urticaria
Clinical narrative: Reaction at Pneumovax injection site.  Raised redness at injection site: 1-2 inch circumference from site of injection right arm (deltoid).  Warm to touch
Age: 19.0
Sex: M
Vaccine: MEN
Symptoms: Muscular weakness
Clinical narrative: Patient receive meningococcal vaccine on 8/10/5. In late September or early October the patient developed weakness in the left hand and had trouble playing the clarinet and piano.  The patient was referred for physical therapy.  Symptoms resolved after approximately 30 days and physical therapy.
Age: 72.0
Sex: F
Vaccine: PPV
Symptoms: Erythema, Feeling hot, Pain, Swelling
Clinical narrative: Pt. complained of 12-24 hrs after receiving Pneumovax patient complained of swelling, redness, warmth from deltoid to elbow.  And ached also. Resolved 72 hr after shot.
Age: 73.0
Sex: M
Vaccine: PPV
Symptoms: Rash
Clinical narrative: Diffuse rash on upper chest and back.
Age: 67.0
Sex: M
Vaccine: PPV
Symptoms: Injection site erythema, Pain
Clinical narrative: Patient experienced pain and redness at injection site as well as fever.
Age: 0.02
Sex: M
Vaccine: HEP
Symptoms: Irritability, Sleep phase rhythm disturbance, Somnolence
Clinical narrative: Parents describe child as excessively sleepy after receiving Hepatitis B vaccine.  Woke for feeding, but slept other times, unlike usual behavior.  Cranky 12/29-12/30.  Normal behavior thereafter.
Age: 55.0
Sex: M
Vaccine: TD
Symptoms: Blood glucose increased
Clinical narrative: Abnormally high blood sugar reading after evening meal. States no change in diet, activity normal reading of 130 or less.  1-11/06- Morning reading 102 (which is his normal range).
Age: 1.01
Sex: F
Vaccine: MMR, VARCEL
Symptoms: Injection site erythema, Skin ulcer
Clinical narrative: Immediate redness/urticarial lesion at site of Varicella vaccine.  Resolved with cold compress and dose of antihistamine.
Age: 0.64
Sex: M
Vaccine: MMRV
Symptoms: Erythema, Oedema
Clinical narrative: Within 2 minutes of vaccine, edema and erythema of left thigh, then flushing/erythema of both legs and arms.  Benadryl 1 tsp given.
Age: 39.0
Sex: M
Vaccine: UNK
Symptoms: Abdominal pain, Arthralgia, Back pain, Balance disorder, Diarrhoea
Clinical narrative: Abdominal pain, allergies, balance problems, diarrhea, digestive problems, hear ringing in ears, pain back, pain knees and hips, rashes on face, skin with rash, pain stomach, pain ear, and for last sleep too much sleeping.
Age: 39.0
Sex: M
Vaccine: UNK
Symptoms: Dyspepsia, Hypersensitivity, Rash, Skin reaction, Sleep disorder
Clinical narrative: Abdominal pain, allergies, balance problems, diarrhea, digestive problems, hear ringing in ears, pain back, pain knees and hips, rashes on face, skin with rash, pain stomach, pain ear, and for last sleep too much sleeping.
Age: 39.0
Sex: M
Vaccine: UNK
Symptoms: Tinnitus
Clinical narrative: Abdominal pain, allergies, balance problems, diarrhea, digestive problems, hear ringing in ears, pain back, pain knees and hips, rashes on face, skin with rash, pain stomach, pain ear, and for last sleep too much sleeping.
Age: 1.02
Sex: F
Vaccine: PNC, VARCEL
Symptoms: Injection site erythema, Injection site vesicles
Clinical narrative: 1 AND 1/2 CM OF ERYTHEMA AT SHOT SITE WITH 2 VESICLES. ONE VESICLE CRUSTED.
Age: 58.0
Sex: M
Vaccine: FLU3
Symptoms: Balance disorder, Blood test normal, Gait disturbance, Hypoaesthesia, Lumbar puncture normal
Clinical narrative: Symptoms began next day-initially aching and stiffness in neck and shoulders.  Following day began feeling weakness and unsteadiness in legs, and tingling and numbness in hands.  Worsened over 3-4 week period.  12/7/05 app't with internist.  He set up spinal MRI, blood tests, and appointment with neurologist.  1/2/06 app't with neurologist.  Diagnosis post vaccinial transverse myelitis.  He set up brain MRI and lumbar puncture procedure, as well as a 12 day program of interveinous and oral steroids. Information from medical records state abnormal gait.msv Follow-up: Transverse myelitis. No improvement.
Age: 58.0
Sex: M
Vaccine: FLU3
Symptoms: Muscular weakness, Musculoskeletal stiffness, Myelitis transverse, Nuclear magnetic resonance imaging brain normal, Nuclear magnetic resonance imaging spinal cord abnormal
Clinical narrative: Symptoms began next day-initially aching and stiffness in neck and shoulders.  Following day began feeling weakness and unsteadiness in legs, and tingling and numbness in hands.  Worsened over 3-4 week period.  12/7/05 app't with internist.  He set up spinal MRI, blood tests, and appointment with neurologist.  1/2/06 app't with neurologist.  Diagnosis post vaccinial transverse myelitis.  He set up brain MRI and lumbar puncture procedure, as well as a 12 day program of interveinous and oral steroids. Information from medical records state abnormal gait.msv Follow-up: Transverse myelitis. No improvement.
Age: 58.0
Sex: M
Vaccine: FLU3
Symptoms: Pain, Paraesthesia
Clinical narrative: Symptoms began next day-initially aching and stiffness in neck and shoulders.  Following day began feeling weakness and unsteadiness in legs, and tingling and numbness in hands.  Worsened over 3-4 week period.  12/7/05 app't with internist.  He set up spinal MRI, blood tests, and appointment with neurologist.  1/2/06 app't with neurologist.  Diagnosis post vaccinial transverse myelitis.  He set up brain MRI and lumbar puncture procedure, as well as a 12 day program of interveinous and oral steroids. Information from medical records state abnormal gait.msv Follow-up: Transverse myelitis. No improvement.
Age: 0.34
Sex: F
Vaccine: HBHEPB, IPV, PNC
Symptoms: Injection site erythema, Pyrexia
Clinical narrative: Post vaccination fever of 102.2 deg F, erythema at rt leg injection site.
Age: 30.0
Sex: F
Vaccine: HEP
Symptoms: Multiple sclerosis, Myelitis transverse, Pain, Rash, Urticaria
Clinical narrative: 1 week after Hep B vaccine I developed a hive like rash on my lower extremities and trunk for which I returned to occupational health.  This rash went away.  I was well until February 2003 when I developed burning pain in my legs and trunk and was subsequently diagnosed with transverse myelitis and multiple sclerosis.  I wasn't aware of the possible link between this illness and the hepatitis B vaccine until doing some research yesterday. Fatigue, numbness of hands, neck pain, dizzy spells, sexual dysfunction
Age: 39.0
Sex: M
Vaccine: PPV
Symptoms: Chills, Injection site erythema, Joint range of motion decreased, Pain, Pyrexia
Clinical narrative: fever, chills, fainting spell, severe body aches, redness of arm that injection was given-from shoulder to elbow, severe arm pain-limited movement in arm. Still having low grade fever and arm pain and redness.
Age: 39.0
Sex: M
Vaccine: PPV
Symptoms: Syncope
Clinical narrative: fever, chills, fainting spell, severe body aches, redness of arm that injection was given-from shoulder to elbow, severe arm pain-limited movement in arm. Still having low grade fever and arm pain and redness.
Age: 1.27
Sex: F
Vaccine: DTAP, PNC
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: L thigh with red, slightly swollen area 5cm x 8cm surrounding injection site.  Symptoms started at night no fever.  Treated with Keflex, follow up in 2 weeks.
Age: 4.0
Sex: M
Vaccine: PNC
Symptoms: Injection site erythema, Swelling, Urticaria
Clinical narrative: 11-15-05 Arm with large reddened area at injection site; 11-17-05 Total body urticaria and swelling, temp 102.  Given Benadryl, cold compresses; 11-23-05 Mom took to Dr. and he said give Benadryl.; 11-30-05 Saw Dr at Head Start.  Continue Benadryl and decrease baths; 12-14-05 Dr at Head Start gave Cortisone Topical and lotion.
Age: 1.0
Sex: M
Vaccine: MMR
Symptoms: Vaccination complication, Viral infection
Clinical narrative: Breakthrough Varicella-large outbreak >100 lesions despite vaccination.  Sibling with same, also vaccinated.
Age: 1.25
Sex: F
Vaccine: DTPHIB
Symptoms: Skin ulcer, Vaccination complication, Viral infection
Clinical narrative: Breakthrough varicella-large outbreak- 50 lesions despite vaccination. Sibling also outbreak and vaccinated.
Age: 11.0
Sex: F
Vaccine: TDAP
Symptoms: Injection site erythema, Injection site oedema
Clinical narrative: Erythema and swelling 6 1/2 inches x 6 inches. Right deltoid.
Age: 0.22
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC
Symptoms: Application site oedema, Crying, Erythema, Irritability
Clinical narrative: Erythema and edema at administration site extending up anterior thigh to groin and down to foot of both lower extremities.  No fever.  Patient crying and fussy.
Age: 23.0
Sex: F
Vaccine: PPV
Symptoms: Activated partial thromboplastin time prolonged, Anorexia, Antinuclear antibody positive, Bacterial infection, Candidiasis
Clinical narrative: It was reported in a published article, title as stated above and presented at the 2005 annual meeting of the American college of allergy, asthma and immunology, Nov 3-9 2005 concerning a 23 year old female with chronic mucocutaneous candidiasis who began to suffer from persistent thrush, failure to thrive, recurrent otitis media (staph aureus) and pneumonia (staph aureus and pseudomonas aeruginosa) since 6 weeks of age, who was vaccinated with PNEUMOVAX 23 vaccine (manufacturer unknown), (dose, duration and indication not reported). At age 4, she was noted to have poor antibody response to pneumococcal polysaccharide antigen, but normal to diphtheria and tetanus. Pneumonia episodes decreased with intravenous immunoglobulin IVIG at age 6. At 11 years of age, she developed persistent times capitis and severe Coombs positive hemolytic anemia. Four months later, she was noted to be very fatigued, slightly jaundiced and chest x ray showed pleural pericardial effusions. At 12 years of age, she developed severe Candida esophagitis and ulcerations. She had 2 times PBMN stem cell transplantation from HLA identical brother at 17 years of age without any reconstitution. At age 17 years she had depressed chemotactic response to FMLP low IgA, IgG2, and C4 levels. Low T cell (CD3+560 /ul, CD4+310/ul, CD8+170/ul,) and NK cell CD 16+56+:30/ul) counts were found at age 18. Candida albicans was isolated several times in KOH preparations and cultures from skin, mouth tongue in addition to her severe Candida esophagitis. At 18 years of age, she was diagnosed to have systemic lupus erythematous SLE on the basis of Coombs + hemolytic anemia, double stranded, deoxyribonucleic acid analysis (dsDNA) (1:20) serum antinuclear antibodies test ANA positivity (1:320) serositis (pericardial) and prolonged activated partial thromboplastin time PPT with positive anticardiolipin antibodies besides clinical findings. At age 23, she was admitted to the hospital due to Coombs + hemolytic anemia second time and died due to multiple organ failure. The authors state that chronic mucocutaneous candidiasis CMC is a heterogeneous group of diseases characterized by persistent yeast infection usually with Candida albicans and described for the first time, a patient with CMC that was diagnosed with SLE, with clinical as well as lab findings. Additional information is not expected. A copy of the published article is attached as further documentation of the patients experience.
Age: 23.0
Sex: F
Vaccine: PPV
Symptoms: Coombs indirect test positive, Coombs positive haemolytic anaemia, Drug ineffective, Fatigue, Fungal infection
Clinical narrative: It was reported in a published article, title as stated above and presented at the 2005 annual meeting of the American college of allergy, asthma and immunology, Nov 3-9 2005 concerning a 23 year old female with chronic mucocutaneous candidiasis who began to suffer from persistent thrush, failure to thrive, recurrent otitis media (staph aureus) and pneumonia (staph aureus and pseudomonas aeruginosa) since 6 weeks of age, who was vaccinated with PNEUMOVAX 23 vaccine (manufacturer unknown), (dose, duration and indication not reported). At age 4, she was noted to have poor antibody response to pneumococcal polysaccharide antigen, but normal to diphtheria and tetanus. Pneumonia episodes decreased with intravenous immunoglobulin IVIG at age 6. At 11 years of age, she developed persistent times capitis and severe Coombs positive hemolytic anemia. Four months later, she was noted to be very fatigued, slightly jaundiced and chest x ray showed pleural pericardial effusions. At 12 years of age, she developed severe Candida esophagitis and ulcerations. She had 2 times PBMN stem cell transplantation from HLA identical brother at 17 years of age without any reconstitution. At age 17 years she had depressed chemotactic response to FMLP low IgA, IgG2, and C4 levels. Low T cell (CD3+560 /ul, CD4+310/ul, CD8+170/ul,) and NK cell CD 16+56+:30/ul) counts were found at age 18. Candida albicans was isolated several times in KOH preparations and cultures from skin, mouth tongue in addition to her severe Candida esophagitis. At 18 years of age, she was diagnosed to have systemic lupus erythematous SLE on the basis of Coombs + hemolytic anemia, double stranded, deoxyribonucleic acid analysis (dsDNA) (1:20) serum antinuclear antibodies test ANA positivity (1:320) serositis (pericardial) and prolonged activated partial thromboplastin time PPT with positive anticardiolipin antibodies besides clinical findings. At age 23, she was admitted to the hospital due to Coombs + hemolytic anemia second time and died due to multiple organ failure. The authors state that chronic mucocutaneous candidiasis CMC is a heterogeneous group of diseases characterized by persistent yeast infection usually with Candida albicans and described for the first time, a patient with CMC that was diagnosed with SLE, with clinical as well as lab findings. Additional information is not expected. A copy of the published article is attached as further documentation of the patients experience.
Age: 23.0
Sex: F
Vaccine: PPV
Symptoms: Immunoglobulins decreased, Jaundice, Laboratory test abnormal, Multi-organ failure, Oesophageal ulcer
Clinical narrative: It was reported in a published article, title as stated above and presented at the 2005 annual meeting of the American college of allergy, asthma and immunology, Nov 3-9 2005 concerning a 23 year old female with chronic mucocutaneous candidiasis who began to suffer from persistent thrush, failure to thrive, recurrent otitis media (staph aureus) and pneumonia (staph aureus and pseudomonas aeruginosa) since 6 weeks of age, who was vaccinated with PNEUMOVAX 23 vaccine (manufacturer unknown), (dose, duration and indication not reported). At age 4, she was noted to have poor antibody response to pneumococcal polysaccharide antigen, but normal to diphtheria and tetanus. Pneumonia episodes decreased with intravenous immunoglobulin IVIG at age 6. At 11 years of age, she developed persistent times capitis and severe Coombs positive hemolytic anemia. Four months later, she was noted to be very fatigued, slightly jaundiced and chest x ray showed pleural pericardial effusions. At 12 years of age, she developed severe Candida esophagitis and ulcerations. She had 2 times PBMN stem cell transplantation from HLA identical brother at 17 years of age without any reconstitution. At age 17 years she had depressed chemotactic response to FMLP low IgA, IgG2, and C4 levels. Low T cell (CD3+560 /ul, CD4+310/ul, CD8+170/ul,) and NK cell CD 16+56+:30/ul) counts were found at age 18. Candida albicans was isolated several times in KOH preparations and cultures from skin, mouth tongue in addition to her severe Candida esophagitis. At 18 years of age, she was diagnosed to have systemic lupus erythematous SLE on the basis of Coombs + hemolytic anemia, double stranded, deoxyribonucleic acid analysis (dsDNA) (1:20) serum antinuclear antibodies test ANA positivity (1:320) serositis (pericardial) and prolonged activated partial thromboplastin time PPT with positive anticardiolipin antibodies besides clinical findings. At age 23, she was admitted to the hospital due to Coombs + hemolytic anemia second time and died due to multiple organ failure. The authors state that chronic mucocutaneous candidiasis CMC is a heterogeneous group of diseases characterized by persistent yeast infection usually with Candida albicans and described for the first time, a patient with CMC that was diagnosed with SLE, with clinical as well as lab findings. Additional information is not expected. A copy of the published article is attached as further documentation of the patients experience.
Age: 23.0
Sex: F
Vaccine: PPV
Symptoms: Oesophagitis, Otitis media, Pericardial effusion, Pleural effusion, Pneumonia
Clinical narrative: It was reported in a published article, title as stated above and presented at the 2005 annual meeting of the American college of allergy, asthma and immunology, Nov 3-9 2005 concerning a 23 year old female with chronic mucocutaneous candidiasis who began to suffer from persistent thrush, failure to thrive, recurrent otitis media (staph aureus) and pneumonia (staph aureus and pseudomonas aeruginosa) since 6 weeks of age, who was vaccinated with PNEUMOVAX 23 vaccine (manufacturer unknown), (dose, duration and indication not reported). At age 4, she was noted to have poor antibody response to pneumococcal polysaccharide antigen, but normal to diphtheria and tetanus. Pneumonia episodes decreased with intravenous immunoglobulin IVIG at age 6. At 11 years of age, she developed persistent times capitis and severe Coombs positive hemolytic anemia. Four months later, she was noted to be very fatigued, slightly jaundiced and chest x ray showed pleural pericardial effusions. At 12 years of age, she developed severe Candida esophagitis and ulcerations. She had 2 times PBMN stem cell transplantation from HLA identical brother at 17 years of age without any reconstitution. At age 17 years she had depressed chemotactic response to FMLP low IgA, IgG2, and C4 levels. Low T cell (CD3+560 /ul, CD4+310/ul, CD8+170/ul,) and NK cell CD 16+56+:30/ul) counts were found at age 18. Candida albicans was isolated several times in KOH preparations and cultures from skin, mouth tongue in addition to her severe Candida esophagitis. At 18 years of age, she was diagnosed to have systemic lupus erythematous SLE on the basis of Coombs + hemolytic anemia, double stranded, deoxyribonucleic acid analysis (dsDNA) (1:20) serum antinuclear antibodies test ANA positivity (1:320) serositis (pericardial) and prolonged activated partial thromboplastin time PPT with positive anticardiolipin antibodies besides clinical findings. At age 23, she was admitted to the hospital due to Coombs + hemolytic anemia second time and died due to multiple organ failure. The authors state that chronic mucocutaneous candidiasis CMC is a heterogeneous group of diseases characterized by persistent yeast infection usually with Candida albicans and described for the first time, a patient with CMC that was diagnosed with SLE, with clinical as well as lab findings. Additional information is not expected. A copy of the published article is attached as further documentation of the patients experience.
Age: 23.0
Sex: F
Vaccine: PPV
Symptoms: Systemic lupus erythematosus
Clinical narrative: It was reported in a published article, title as stated above and presented at the 2005 annual meeting of the American college of allergy, asthma and immunology, Nov 3-9 2005 concerning a 23 year old female with chronic mucocutaneous candidiasis who began to suffer from persistent thrush, failure to thrive, recurrent otitis media (staph aureus) and pneumonia (staph aureus and pseudomonas aeruginosa) since 6 weeks of age, who was vaccinated with PNEUMOVAX 23 vaccine (manufacturer unknown), (dose, duration and indication not reported). At age 4, she was noted to have poor antibody response to pneumococcal polysaccharide antigen, but normal to diphtheria and tetanus. Pneumonia episodes decreased with intravenous immunoglobulin IVIG at age 6. At 11 years of age, she developed persistent times capitis and severe Coombs positive hemolytic anemia. Four months later, she was noted to be very fatigued, slightly jaundiced and chest x ray showed pleural pericardial effusions. At 12 years of age, she developed severe Candida esophagitis and ulcerations. She had 2 times PBMN stem cell transplantation from HLA identical brother at 17 years of age without any reconstitution. At age 17 years she had depressed chemotactic response to FMLP low IgA, IgG2, and C4 levels. Low T cell (CD3+560 /ul, CD4+310/ul, CD8+170/ul,) and NK cell CD 16+56+:30/ul) counts were found at age 18. Candida albicans was isolated several times in KOH preparations and cultures from skin, mouth tongue in addition to her severe Candida esophagitis. At 18 years of age, she was diagnosed to have systemic lupus erythematous SLE on the basis of Coombs + hemolytic anemia, double stranded, deoxyribonucleic acid analysis (dsDNA) (1:20) serum antinuclear antibodies test ANA positivity (1:320) serositis (pericardial) and prolonged activated partial thromboplastin time PPT with positive anticardiolipin antibodies besides clinical findings. At age 23, she was admitted to the hospital due to Coombs + hemolytic anemia second time and died due to multiple organ failure. The authors state that chronic mucocutaneous candidiasis CMC is a heterogeneous group of diseases characterized by persistent yeast infection usually with Candida albicans and described for the first time, a patient with CMC that was diagnosed with SLE, with clinical as well as lab findings. Additional information is not expected. A copy of the published article is attached as further documentation of the patients experience.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Chest discomfort, Dyspnoea, Face oedema, Periorbital oedema
Clinical narrative: Client reports constricting feeling in chest, cough becoming productive, difficulty breathing and those symptoms lasted through PM. Client went to bed. Awoke next morning with face/eyes swollen - these symptoms lasted through next day. Entire event lasted approximately 24 hours. Client did not seek any treatment.
Age: 4.0
Sex: F
Vaccine: FLU3
Symptoms: Depressed level of consciousness, Lethargy, Vomiting
Clinical narrative: Within 1-2 hours of vaccine, pt became lethargic and difficult to arouse. Vomited once.
Age: 0.96
Sex: M
Vaccine: FLU3
Symptoms: Injection site abscess
Clinical narrative: PC from PGM states infant with big knot in leg. Saw PMD - referred to surgeon. Had I and D of abscess per PGM 1/2 inch wide 1 inch in depth that is patched daily and placed on 10 days of antibiotics. To follow-up with surgeon. 1/05/2006 C and S done. See MD notes (attached). Abscess left thigh - I & D on 12/28/2005. Culture Staph A, susceptible to Bactrim.
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site erythema, Injection site oedema, Injection site warmth
Clinical narrative: Right arm became red, swollen, warm on 11/28/2006. Area of erythema at office visit = 3 inches circular with mild swelling (date of visit 1/30/2006). Full ROM, no fevers. According to mom, much improved with topical hydrocortisone cream over last 24 hours.
Age: 0.18
Sex: M
Vaccine: DTAP, HIBV, IPV, PNC
Symptoms: Diarrhoea, Pyrexia
Clinical narrative: Fever 103.9 - diarrhea today. Pt has had recurrent diarrhea illness.
Age: 5.0
Sex: F
Vaccine: DTAP, FLU3, MMR
Symptoms: Rash, Urticaria
Clinical narrative: Child had 6 cm. rash on right deltoid area and hives on trunk of body.
Age: 17.0
Sex: M
Vaccine: MNQ
Symptoms: Chills, Dizziness, Pyrexia
Clinical narrative: Fever, chills, dizziness.
Age: 10.0
Sex: M
Vaccine: HEP
Symptoms: Injection site erythema, Injection site inflammation, Injection site warmth, Pyrexia
Clinical narrative: Local inflammation at injection site, which was the left deltoid, accompanied by a temperature of 99.2 for a duration of approximately 1 hour. Redness at site lasted for six days. At maximum size it was approximately 4inches in size. Returned to school health center on 2/1/06 with c/o non itching, lacy rash to right arm which was hot to the touch.
Age: 0.2
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC
Symptoms: Crying
Clinical narrative: Mom states after 2 month shots were given on 12/8/05 baby cried for 3 hours straight.
Sex: M
Vaccine: FLU3
Symptoms: Hypoaesthesia
Clinical narrative: Pt reported numbness down arm from site of flu injection. This occurred 3 weeks following administration of immunization.
Age: 7.0
Sex: M
Vaccine: VARCEL
Symptoms: Febrile convulsion
Clinical narrative: Child received Varivax on 01/30/06 and experienced a febrile seizure on 1/31/06. Child was admitted to the hospital.
Age: 51.0
Sex: F
Vaccine: SMALL
Symptoms: Infection transmission via personal contact, Rash
Clinical narrative: AFTER VACCINIA OF HUSBAND PRE-DEPLOYMENT, PATIENT DEVELOPED IDENTICAL RASH ON THE DELTOID ARE CORRESPONDING TO THAT WHICH WOULD BE IN CONTACT WITH HUSBAND (VACCINEE) IN BED. VERY LIKELY SECONDARY VACCINATION BY CONTAGION. PATIENT WAS VACCINATED IN CHILDHOOD ROUTINELY.
Age: 4.0
Sex: M
Vaccine: DTAP, HEP, IPV, MMR
Symptoms: Injection site erythema, Injection site induration, Injection site swelling, Injection site warmth
Clinical narrative: Approximately 40mm in diameter hard tissue, redness, swelling and warmth to touch, non-painful per 4 year old child to left deltoid area, developing approximately 24 hours after immunization administered. Recommended apply cold compress, monitor temperature, assess for signs and symptoms of infection/abcess and administer tylenol for pain if needed. Currently no fever. If fever or other signs and symptoms of infection develop encouraged parent to see MD or take child to urgent care if after hours. Mom verbalizes understanding and repeats at least 3 signs and symptoms of infection.
Age: 35.0
Sex: M
Vaccine: HEP, SMALL, TYP
Symptoms: Injection site erythema
Clinical narrative: THE PATIENT DEVELOPED DIFFUSE ERYTHEMA OVER LEFT DELTOID AREA (VACCINATION SITE) AND SCATTERED PUSTULES on neck, torso, arms. Afebrile. No peripheral lymphadenopathy. Otherwise no generalized symptoms.
Age: 1.5
Sex: F
Vaccine: DTAP, IPV
Symptoms: Convulsion, Laboratory test abnormal, Pyrexia
Clinical narrative: Onset of seizures 8 1/2 hr after vaccinations. Two seizures at home two seizures in ER. Treated with acyclovir until HSV PCR came back and was negative. Treated with ceftriaxone for 98 hrs. Pt had fever upon arrival to ER of 101.8. Seizures were described as tonic clonic and lasting 20 - 30 seconds. 4/20/06 Received medical records from hospital which revealed patient had fever & tonic clonic sz's witness in ER in addition to 2 sz at home.  Patient's father had cold sore & patient had vesicular rash on chin & herpes encephalitis was suspected however, septic w/u & all c/s were neg.  Dx: complex febrile seizure/ss
Age: 1.5
Sex: M
Vaccine: MMR, UNK, VARCEL
Symptoms: Rash papular, Skin ulcer, Viral infection
Clinical narrative: Several papular lesions on body, 1-2 appear vesicular.  Diagnosis: Varicella  Treatment: Symptomatic
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, PNC
Symptoms: Cough, Erythema, Rash, Urticaria, Wheezing
Clinical narrative: Patient given DTAP #5, IPV#4, PCV#4 at approx 2:50 pm.  Pt was back in clinic with new onset cough and urticarial rash on face, torso, scalp, neck, both ears were bright red.  On exam had near O2 Sat 98% but bibasilar fine wheezing.  He was given IM BENADRYL, 25mg & srepinehrine 1:10du/ml.  Responded within minute.  Rash and wheeze cough were gone-discharged 1 minute later with by mouth BENADRYL.
Sex: U
Vaccine: DT
Symptoms: Asthenia, Fatigue, Joint range of motion decreased, Pain, Pyrexia
Clinical narrative: After get DT patient felt weak, fatigue, fever, body ache, L arm pain, limited motion of arm due to vaccines.  No cough, no rhinorrhea, no vomit/diarrhea, no redness at site, no rash, no shortness of breath.
Age: 4.0
Sex: M
Vaccine: DTAP, HEPA, IPV, MMR
Symptoms: Pain, Swelling
Clinical narrative: Swelling of the left thigh, pain with ambulation.  No fever, fatigue or other systemic symptoms.  Swelling decreased the following day.  On examination 2 days after administration, thigh circumference 29.5 cm vs 28 cm on right, ambulating well, no indication of infection.
Age: 0.35
Sex: F
Vaccine: DTAPHEPBIP, PNC
Symptoms: Erythema
Clinical narrative: Redness on face.
Age: 42.0
Sex: F
Vaccine: RAB
Symptoms: Asthenia, Dizziness, Fatigue, Myalgia, Rash
Clinical narrative: Weakness, fatigue, dizziness, myalgia, rash.
Age: 1.4
Sex: M
Vaccine: DTAP, HEPA, HIBV
Symptoms: Rash papular, Urticaria
Clinical narrative: Papules at site of immunization and hives generalized the following day.
Age: 31.0
Sex: M
Vaccine: HEPAB
Symptoms: Erythema, Pruritus, Skin burning sensation, Swelling
Clinical narrative: Received multiple immunizations during basic training in early March 2005. Immunization records show patient received Twinrix on 9 March 2005, but he specifically recalls receiving a separate shot about 2 weeks after that 3/22/05 and was told it was both Hep A and Hep B.  About 24 hours after receiving that vaccine (am of 3/23/05) he experienced a generalized burning sensation that he describes as 'on fire from the inside out'.  The sensation increased with touch; for example, the weight of his BDUs against no hives or individual lesions were noted; if he scratched, especially on his arms and back, the skin became red and swollen.  He did not experience pharyngeal or glossal edema, hoarseness, dyspnea, bronchospasms, angioedema, or other systemic symptoms.  He sought evaluation the following day (3/24/05) and was prescribed  Calamine lotion, Atarax and something for scabies.  He did not use the Ellmite, but the Atarax and calamine seemed to help.  He had also been prescribed an antihistamine for hay fever previously and took that daily until October 2005. When he ran out, while on leave, he began to experience pruritus; he then took OTC CTM which helped.  More recently he was changed to Claritin 10 mg a day and that controls the itching. Prior to symptom onset, he denies a history of animal or insect bite, trauma, infections, fever, malaise, joint pain, or close contacts with similar symptoms.  In 1999, patient broke out in hives and at the time it was attributed to exposure to mold; however when he moved away from the mold, he continued to experience urticaria.  He later was evaluated by a Dermatologist and was told he had chronic urticaria; he was started on 3 medications to asymptomatic; after he stopped them, he did not have a reoccurrence.  He has +Dermatographism.  His PMH/PSH included hernia repair, cat scratch fever (diagnosed per biopsy of lymph node in August 2005), fracture of his right leg, with surgical repair, and hay fever.  No know drug allergies.  Symptom: Paresthesia Comment: 'on fire from inside out'; generalized burning-type sensation increased with touch like BDUs against the skin. Symptom: Pruritus Comment: itching sensation, but no lesions; skin became red and swollen after scratching, especially on back and arms.
Age: 68.0
Sex: F
Vaccine: FLU3
Symptoms: Erythema, Eye disorder, Eye swelling, Face oedema, Ocular hyperaemia
Clinical narrative: Initial report received from the patient on 1/24/2006. The 68 year old female patient with a medical history of glaucoma, had received an injection of Fluzone SV 2005-2006 USP, lot number not reported, in the left deltoid on 11/01/2005. One day later, her face swelled up and she developed red blotches on her face. Her eyes were red and swollen. She also developed a sore between her eyes, which became painful and itchy. She was seen by her eye specialist two to three weeks later and was treated with Benadryl and steroids. The patient reported that she now has a deep scar between her eyes and cannot wear glasses because of her puffed eyes. She has not recovered from these events.
Age: 68.0
Sex: F
Vaccine: FLU3
Symptoms: Pain, Pruritus, Rash macular
Clinical narrative: Initial report received from the patient on 1/24/2006. The 68 year old female patient with a medical history of glaucoma, had received an injection of Fluzone SV 2005-2006 USP, lot number not reported, in the left deltoid on 11/01/2005. One day later, her face swelled up and she developed red blotches on her face. Her eyes were red and swollen. She also developed a sore between her eyes, which became painful and itchy. She was seen by her eye specialist two to three weeks later and was treated with Benadryl and steroids. The patient reported that she now has a deep scar between her eyes and cannot wear glasses because of her puffed eyes. She has not recovered from these events.
Age: 18.0
Sex: F
Vaccine: HEP
Symptoms: Asthenia, Back pain, Chest pain, Dizziness, Dyspnoea
Clinical narrative: Patient received IM hepatitis B vaccine on 10/27/2005. Hives developed 27th worse on 28th, 29th and 30th. Came to ER on 10/29/2005 and received IV meds back on 10/30/2005 with worsening of symptoms. Face, lips swollen hives over entire body scattered and complaint of shortness of breath. 2/6/06 ER medical records received from hospital which stated patient experienced urticaria, swelling of lips/throat, SOB. Dx erthema multiforme & allergic reaction.  PMH: allergy to PCN./ss
Age: 18.0
Sex: F
Vaccine: HEP
Symptoms: Face oedema, Hypersensitivity, Nervousness, Rash, Urticaria
Clinical narrative: Patient received IM hepatitis B vaccine on 10/27/2005. Hives developed 27th worse on 28th, 29th and 30th. Came to ER on 10/29/2005 and received IV meds back on 10/30/2005 with worsening of symptoms. Face, lips swollen hives over entire body scattered and complaint of shortness of breath. 2/6/06 ER medical records received from hospital which stated patient experienced urticaria, swelling of lips/throat, SOB. Dx erthema multiforme & allergic reaction.  PMH: allergy to PCN./ss
Age: 54.0
Sex: F
Vaccine: FLUX
Symptoms: Eye discharge, Eye inflammation, Eye irritation
Clinical narrative: Eyes became itchy 1 1/2-2 hours after flu shot.  During night yellow discharge from eyes and puffy lids. Eyelashes were stuck together. This lasted for about 24 hours.
Age: 55.0
Sex: M
Vaccine: UNK
Symptoms: Asthenia, Back pain, Fatigue, Gastrooesophageal reflux disease
Clinical narrative: Acid reflux - (Omeprazole);Pain lower back (Naproxen & Flexeril);Medicine adm by VA Fatigue;Energy loss
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Cellulitis, Erythema, Feeling hot
Clinical narrative: R deltoid 2" diameter area of erythema and warmth =cellulitis.  Keflex 250mg four times a day x 10 days.
Age: 13.0
Sex: M
Vaccine: HEP, HEPA
Symptoms: Pain, Sensation of heaviness, Skin discolouration, Swelling
Clinical narrative: Parent took child to phyisican with noting left arm swollen and "purple looking".  Child complained of left arm "pain, heavy feeling."  Per mom Dr. sent child home to put warm water on it, no meds given and mom says Dr. said not to get HAV shot again.
Age: 1.01
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Laboratory test abnormal, Neutropenia, Pyrexia
Clinical narrative: Fevers 6+ days, to 103 degrees.  Neutropenia, severe (A.N.C. -89)
Age: 1.03
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Erythema, Injection site induration, Swelling, Urticaria
Clinical narrative: Hard, red swelling, with whitish blue center. Hive all over body. 6 hours after injection. TX: Tylenol PRN; Benadryl PRN
Age: 1.3
Sex: M
Vaccine: DTAP, HEP, HIBV, PNC
Symptoms: Difficulty in walking, Pain, Swelling
Clinical narrative: Pt received vaccines on 2/2/06, later in the day his right leg became swollen and painful, refused to walk or move the leg.  Child taken to emergency room, given tylenol with codeine.  Returned to our office 2/3/06, fever of 104.0 axillary reported by mother of child earlier in the morning , swelling and pain is decreasing.  CBC within normal limits.
Age: 1.34
Sex: M
Vaccine: IPV, MMR, VARCEL
Symptoms: Irritability, Rash
Clinical narrative: One day after receiving immunizations, mother called to report generalized rash and fussiness.
Age: 22.0
Sex: F
Vaccine: HEP
Symptoms: Dizziness, Erythema, Pain
Clinical narrative: 1/30/06, 11:45AM: HepB administered into right deltoid. At 4pm on 1/30/06 experienced redness, pain, dizziness and lightheaded feeling.    2/2/06:  Vaccinating nurse made follow-up call to patient.  Patient expressed that arm was much improved, with only minimal soreness.  Patient did not seek private MD consult as recommended by vaccinating RN.
Age: 49.0
Sex: F
Vaccine: FLU3, HEPA, PPV
Symptoms: Injection site warmth, Pain, Swelling
Clinical narrative: R arm pain and swelling post flu and pnemovax injections warm to touch. Sx noted after 24 hrs of injections- local reaction.
Age: 71.0
Sex: F
Vaccine: HEPA, YF
Symptoms: Anxiety, Dry mouth, Throat tightness, Tongue disorder
Clinical narrative: Approximately 40 minutes after receiving Yellow Fever vaccine and Hepatitis A vaccine, at 12:10 PM, client returned to clinic and complained of thickening tongue and excessively dry mouth.  Client refused Benadryl, stating, "It makes me too drowny.  I don't want that." BP 120/76, P88, R 20.  Physician notified at about 12:15.  After speaking with client, 911 was called, at about 12:18, and physician also alerted the ER doctor that client would be arriving via ambulance. No stridor, no shortness of breath and no gasping noted, though client became increasingly anxious and reported her throat felt a little tight.  O2 @ 2L via nasal cannula started. EMT's arrived at approximately 12:27 and took over care of the client at approximately 12:35.
Age: 1.1
Sex: F
Vaccine: DTAP, HIBV, MMR, PNC, VARCEL
Symptoms: Erythema, Rash
Clinical narrative: Parent called clinic to report child had several small raised red "bumps" on left leg, remembered nurse told him could be side effect of varicella vaccine but calling to be sure. Asked how long bumps take to go away and should any precautions be taken.
Age: 20.0
Sex: F
Vaccine: MNQ
Symptoms: Headache, Lymphadenopathy, Pharyngolaryngeal pain, Pyrexia, Tremor
Clinical narrative: The day after the vaccine, symptoms were headache, sore throat, high fever, trembling and vomiting, very swollen lymph nodes.  Treated with a steroid, epinephrine, vicodin, an antibiotic, and benadryl and 4 hours on an IV.
Age: 20.0
Sex: F
Vaccine: MNQ
Symptoms: Vomiting
Clinical narrative: The day after the vaccine, symptoms were headache, sore throat, high fever, trembling and vomiting, very swollen lymph nodes.  Treated with a steroid, epinephrine, vicodin, an antibiotic, and benadryl and 4 hours on an IV.
Age: 43.0
Sex: F
Vaccine: FLU3
Symptoms: Abasia, Amnesia, Balance disorder, Blood creatine phosphokinase increased, Chest X-ray abnormal
Clinical narrative: 10/19 begin to feel bad, 10/21 high fever will not come down even with Tylenol or Advil,  10/24 ER chest X ray diagnosed with pneumonia, 10/25 Dr appt to check medication, 10/29 noticed weakness in legs beginning in morning balance problems and weakness worsen, 10/30, ambulance to ER, 11/02 spinal tap clear symptoms paralysis, foot drop, muscle spasms, inflamed nerve endings in legs and feet, 11/04 transferred to another hospital, 11/04 extremely high protein level in blood due to deterioration of muscles. Start on baclofen to stop spasms, 11/09 protein level back to normal, 11/11 transferred to rehab Unit cannot walk at all, 11/14-22 physical therapy 4 times a day for 45 minutes. Learn to walk again, balance problems, diagnosed with Post infectious myositis, released 11/22 on going therapy to improve function. 11/25 begin outpatient therapy 3 times a week on going due to peroneal nerve damage in feet. I have peroneal neuropathy- foot drop due to flu vacine. Swelling of feet and ankles, pain in feet, decreased movement, no feeling in toes ore feet. Still go to physicial therapy to regain strength and flexability. Constatn muscle spasms in feet. Nerve damage from ankles down. 3/31/2010 Follow up: No feeling in feet and legs due to damage to peroneal nerve. Loss of movement in ankles/swelling in feet neurological problems-short term memory loss, difficulty in concentration and difficulty finding words and thoughts.