Age: 75.0
Sex: F
Vaccine: VARZOS
Symptoms: Paraesthesia, Paraesthesia oral, SARS-CoV-2 test negative, Weight increased
Clinical narrative: [injection site] arm pain; severe headache; tiredness(fatigue); eye pain / experiencing shooting pains / pain is very sharp; she can't even open her eyes; food has a metallic taste; numbness in her face especially her lips and tongue / face feels cold but states she can't really feel it / face is numb; face feels cold but states; tongue feels like it is tingling; She is trying different types of food and is gaining weight due to trying to resolve the problem.; This case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 75-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Zostavax (prior vaccination with the live shingles). Concurrent medical conditions included drug intolerance.   On 20th December 2020, the patient received the 2nd dose of Shingrix. On an unknown date, less than 2 months after receiving Shingrix, the patient experienced injection site pain, headache, fatigue, eye pain, mobility decreased, taste metallic, numbness facial, feeling cold, tingling sensation and weight gain. On an unknown date, the outcome of the injection site pain was recovered/resolved and the outcome of the headache, fatigue, eye pain, taste metallic and numbness facial were not recovered/not resolved and the outcome of the mobility decreased, feeling cold, tingling sensation and weight gain were unknown.   The reporter considered the injection site pain, headache, fatigue, eye pain, mobility decreased, taste metallic, numbness facial, feeling cold, tingling sensation and weight gain to be related to Shingrix.  Additional details were reported as follows: The patient received Shingrix and did not had the paperwork in front of her thus she did not had the exact date of the shot or the lot number.  The patient did provide her pharmacy's phone number which should had that information on file and already reported some of these side effects to her pharmacist who encouraged her to call GSK.  The patient experienced injection site arm pain and unspecified other symptoms which resolved. The patient had fatigue and severe headache which had not fully resolved but are not as severe as they once were. The lingering side effects that was still experiencing 5 weeks. The patient had eye pain and experiencing shooting pains in her eyes that started after the Shingrix shot and was not every day but that the pain was very sharp and that sometime she cannot even open eyes because it was too painful to did so almost like something was in her eye but nothing is in her eye and never had eye pain prior before prior to getting the Shingrix shot. The patient had face events and was experiencing numbness in her face especially her lips and tongue and wants to feel her face again. The patient face feels cold but states she cannot really feel it anymore and face was numb and it was not that way before the Shingrix shot and tongue feels like it was tingling.  The patient would eat food to make the tingling go away but the food has a metallic taste and was trying different types of food and was gaining weight due to trying to resolve the problem and was not trying any brand new foods however.  The reporter thinks the facial events and eye pain are due to the Shingrix because and did not take any medications, did not had Covid, and has not changed her diet, the events started after the Shingix shot and never had them before the shot. The patient did not want to get Shingrix shot 2. The reporter consented to follow up. This case linked with US2021017036, US2021017037 and US2021AMR018312, reported by same reporter.; Sender's Comments:  US-GLAXOSMITHKLINE-US2021017036: US-GLAXOSMITHKLINE-US2021017037: US-GLAXOSMITHKLINE-US2021AMR018312: