Sex: F
Vaccine: COVID19
Symptoms: Dry eye, Eye pruritus, Increased bronchial secretion, Paraesthesia, Pruritus
Clinical narrative: Tickle in throat; Sensation of tightening in throat; Increased mucous production; body-wide intense itchiness; Paraesthesia; Hives began third day in flushes over arms, trunk, face, upper legs; Dry itchy eyes; Dry itchy eyes; This spontaneous case was reported by a consumer and describes the occurrence of THROAT IRRITATION (Tickle in throat), THROAT TIGHTNESS (Sensation of tightening in throat), INCREASED BRONCHIAL SECRETION (Increased mucous production), PRURITUS (body-wide intense itchiness) and PARAESTHESIA (Paraesthesia) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Paraesthesia (Paresthesia of entire right side of body and left hand forearm/ left foot/ left ear since 2010 w/o known cause which flares during some viral infections or intense heat/UV exposure.) since 2010. Concomitant products included CETIRIZINE for an unknown indication.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced THROAT IRRITATION (Tickle in throat), THROAT TIGHTNESS (Sensation of tightening in throat), INCREASED BRONCHIAL SECRETION (Increased mucous production), PRURITUS (body-wide intense itchiness), PARAESTHESIA (Paraesthesia), URTICARIA (Hives began third day in flushes over arms, trunk, face, upper legs), DRY EYE (Dry itchy eyes) and EYE PRURITUS (Dry itchy eyes). At the time of the report, THROAT IRRITATION (Tickle in throat), THROAT TIGHTNESS (Sensation of tightening in throat), INCREASED BRONCHIAL SECRETION (Increased mucous production), PRURITUS (body-wide intense itchiness), PARAESTHESIA (Paraesthesia) and URTICARIA (Hives began third day in flushes over arms, trunk, face, upper legs) outcome was unknown and DRY EYE (Dry itchy eyes) and EYE PRURITUS (Dry itchy eyes) had resolved.            The patient reported that since reaction was managed w/o epinephrine after first dose, it was decided to try second dose (several weeks late) with standby epinephrine and antihistamines (cetirizine) taken prior to vaccination. The reaction began approximately 20 min with tickle in throat, some sensation of tightening and increased mucous production, followed by body wide intense itchiness and paresthesia at approximately 35-40 minutes post vaccination. A second dose of cetirizine was taken at onset. Reportedly, scratchy throat/back mouth did not occur nor did tingling of lips or tongue.  The hives began third day in flushes over arms, trunk, face, upper legs. Dry itchy eyes lasted appx 4 days. As per the patient overall second dose reaction was less severe albeit that it was received quite late.   This case was linked to MOD-2021-004774 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 05-May-2021: Additional information received included no new information.