Age: 53.0
Sex: M
Vaccine: COVID19, COVID19, COVID19, COVID19
Symptoms: Blood cholesterol, Hypocholesterolaemia, Therapeutic response unexpected
Clinical narrative: Dropping of the cholesterol level / LDL Cholesterol had dropped gain from 192 to 173; Drowsiness; Sore arm; Bad Cholesterol went down / Good Cholesterol went up; This spontaneous case was reported by an other health care professional and describes the occurrence of LOW DENSITY LIPOPROTEIN DECREASED (Dropping of the cholesterol level / LDL Cholesterol had dropped gain from 192 to 173), SOMNOLENCE (Drowsiness), PAIN IN EXTREMITY (Sore arm) and THERAPEUTIC RESPONSE UNEXPECTED (Bad Cholesterol went down / Good Cholesterol went up) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 065F21A, 029L20A and 039K20A) for COVID-19 vaccination.     Patient reported zero prescriptions, no drugs, no smoking, no alcohol, just plenty of junk food.  The patient's past medical history included COVID-19 (Doctor's office/urgent care visit) from 15-Apr-2020 to 25-Apr-2020. Concurrent medical conditions included Allergy (Statins allergy) and High cholesterol (Drastic improvement after each COVID vaccine) since 15-Jan-2013.   On 23-Dec-2020 at 1:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 19-Jan-2021 at 1:00 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 15-Nov-2021 at 1:00 PM, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced LOW DENSITY LIPOPROTEIN DECREASED (Dropping of the cholesterol level / LDL Cholesterol had dropped gain from 192 to 173), SOMNOLENCE (Drowsiness), PAIN IN EXTREMITY (Sore arm) and THERAPEUTIC RESPONSE UNEXPECTED (Bad Cholesterol went down / Good Cholesterol went up). At the time of the report, LOW DENSITY LIPOPROTEIN DECREASED (Dropping of the cholesterol level / LDL Cholesterol had dropped gain from 192 to 173), SOMNOLENCE (Drowsiness), PAIN IN EXTREMITY (Sore arm) and THERAPEUTIC RESPONSE UNEXPECTED (Bad Cholesterol went down / Good Cholesterol went up) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 15-Apr-2020, SARS-CoV-2 test false negative: positve (Positive) Positve (Nose Swab). In July 2020, Low density lipoprotein: 140 LDL dropped from 175 to 140. In May 2021, Low density lipoprotein: 163 163. In September 2021, Low density lipoprotein: 192 192. In December 2021, Low density lipoprotein: 173 Dropped again from 192 to 173. On 12-Apr-2022, Low density lipoprotein: 176 176. On 22-Apr-2022, Low density lipoprotein: 144 10 days after the 2nd booster it dropped to 144. On an unknown date, Low density lipoprotein: 175 175.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication reported.  No treatment medication reported.   This case was linked to MOD-2022-564739, MOD-2022-564744, MOD-2022-564750 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 08-Jun-2022: Follow up received. Patient demographics and history updated, lab data added.