Sex: F
Vaccine: COVID19
Symptoms: Anxiety, Feeling abnormal, Heart rate, Palpitations, Tachycardia
Clinical narrative: feel my heart pound really fast/her heart felt like it was pounding out of her chest; feeling of severe doom or dread; felt very bizarre/felt like she was going to lose her breath/felt like she was going to hyperventilate; began to become very tachycardic; This is a spontaneous report from a contactable nurse (patient). A female patient of an unspecified age received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, Solution for injection, Lot Number: EW0130, expiry date not reported), via an unspecified route of administration on 01Apr2021 as a single dose for covid-19 immunisation. The patient's medical history and concomitant medications were not reported. Patient received the first dose of the Pfizer COVID-19 vaccine on 01Apr2021 and she would like to know if she should proceed with getting the second dose based on the nature of her reaction to the first dose. The patient stated, she received the vaccine and then 90 minutes later she began to feel her heart pound really fast and it started to feel like it was pounding out of her chest, accompanied by feeling of severe doom or dread. It felt very bizarre, felt like patient was going to die. She felt like she was going to lose her breath but she didn't. Her throat did not close up. She did not have a rash, and was not itchy anywhere. Patient took some Benadryl right away and it subsided. It lasted about a total 5 minutes, it felt like a very long 5 minutes. The anxiety was the worst she had every experienced. She had never experienced anything like that before. She would like some guidance regarding her second dose. She would like to know any information regarding the efficacy after one dose of the Pfizer COVID-19 vaccine. She also said she began to become very tachycardic on 01Apr2021 and felt extreme anxiety and it was the worst anxiety that came over her. She felt like she was going to die and might call it that and she did not really have trouble breathing but felt like she was going to hyperventilate. Therapeutic measures were taken as a result of the events "feel my heart pound really fast/her heart felt like it was pounding out of her chest" and "felt very bizarre/felt like she was going to lose her breath/felt like she was going to hyperventilate". The patient recovered on an unspecified date in Apr2021 from the events "feel my heart pound really fast/her heart felt like it was pounding out of her chest" and "felt very bizarre/felt like she was going to lose her breath/felt like she was going to hyperventilate". The outcome of the other events reported was unknown.; Sender's Comments: Considering the plausible drug-event temporal association, a contributory role of the suspect product bnt162b2 to the reported events cannot be excluded. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics committees and Investigators, as appropriate.