Age: 75.0
Sex: U
Vaccine: COVID19
Symptoms: Chronic obstructive pulmonary disease
Clinical narrative: severe COPD exacerbation; severe COPD exacerbation; severe COPD exacerbation; oxygen 24/7; This spontaneous case was reported by a consumer and describes the occurrence of OXYGEN THERAPY (oxygen 24/7), the first episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation), the second episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation) and the third episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation) in a 75-year-old patient of an unknown gender who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Respiratory syncytial virus infection (Patient had RSV February 2019 at 75 years old, with COPD, and CHF which almost killed the patient.) in February 2019 and Congestive heart failure (Patient had RSV February 2019 at 75 years old, with COPD, and CHF which almost killed Patient.) in February 2019. Concurrent medical conditions included COPD (Patient had RSV February 2019 at 75 years old, with COPD, and CHF which almost killed patient.) since February 2019.   On 01-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 10-Apr-2021, the patient experienced the first episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation). On 21-Apr-2021, the patient experienced the second episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation). On 28-Apr-2021, the patient experienced the third episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation). In 2021, the patient experienced OXYGEN THERAPY (oxygen 24/7). The patient was treated with OXYGEN for COPD exacerbation, at an unspecified dose and frequency. At the time of the report, OXYGEN THERAPY (oxygen 24/7) and the last episode of CHRONIC OBSTRUCTIVE PULMONARY DISEASE (severe COPD exacerbation) outcome was unknown.            No concomitant medications provided. No treatment information provided. On 10-APR-2021, 21-APR-2021, and 28-APR-2021, the patient had severe COPD exacerbation. At the time of this report. the patient had oxygen 24/7 and patient blames the vaccines.  Company comment: This case concerns a 75 year-old male patient with history of COPD, who experienced the unexpected non-serious events of COPD exacerbation (x3) and Oxygen therapy. The events occurred within a month of the second dose of mRNA-1273 vaccine. The underlying history of COPD likely contributed to the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This case concerns a 75 year-old male patient with history of COPD, who experienced the unexpected non-serious events of COPD exacerbation (x3) and Oxygen therapy. The events occurred within a month of the second dose of mRNA-1273 vaccine. The underlying history of COPD likely contributed to the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.