Age: 41.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Heavy menstrual bleeding, Menstruation irregular, Ultrasound scan vagina
Clinical narrative: Menorrhagia; I had a 5-day-long period that started on 6Mar, 2 days after my second dose. Then another 10-day long period started on 19Mar.; This is a spontaneous report from a contactable consumer, the patient. A 41-year-old non-pregnant female patient received second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, lot number: EN6205) via unspecified route of administration in the left arm on 04Mar2021 at 15:30 (at the age of 41-years-old) as a single dose for COVID-19 immunisation. Medical history included infertility. Concomitant medications included ascorbic acid, pyridoxine hydrochloride, biotin, folic acid, cholecalciferol, cyanocobalamin, riboflavin, Phyto menadione, nicotinamide, calcium pantothenate, ferrous fumarate, calcium carbonate, thiamine mononitrate, magnesium oxide, zinc oxide, beta-carotene, potassium iodide, dl-alpha tocopheryl acetate (NATURE MADE MULTI PRENATAL), folic acid (MANUFACTURER UNKNOWN), vitamin B (MANUFACTURER UNKNOWN), vitamin D (MANUFACTURER UNKNOWN) and ubidecarenone (COQ10). The patient had no known allergies to medications, food or other products. The patient previously received first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, lot number: EM9809) via unspecified route of administration in the left arm on 11Feb2021 at 15:30 (at the age of 41-years-old) as a single dose for COVID-19 immunisation. Prior to the vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient had not been tested for COVID-19. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. On 19Mar2021, at 08:00 the patient experienced menorrhagia and had a 5-day-long period that started on 06Mar2021, 2 days after my second dose. Then another 10-day long period started on 19Mar2021 and period lasted for 10 days was heavy and bright red. It was reported that she had a 5-day-long period that started on 06Mar2021, 2 days after my second dose. Then another 10-day long period started on 19Mar2021 meaning the menstrual cycle starting 19Mar2021 was 13 days long. Patient was consulting a reproductive endocrinologist for infertility and he mentioned that a few of his patients had also seen irregular cycles after the second dose and hence she reported it. According to the patient, irregular menstrual cycle might not be big deal for many women. She was pursuing infertility treatment at age of 41 years, and did not have time to mess up her menstrual cycles.  On 20Mar21, the patient underwent transvaginal ultrasound and doctor notes that her cervix looked normal and uterine lining was shedding like periods, yet her holes in her ovary where eggs ovulated in last cycle had the fluid that was seen during luteal phase. In other words, it sounds like part of her system is in the follicular phase and part of her system is in the luteal phase. The events resulted in a visit to the doctors or other healthcare professional office/clinic visit. The patient did not receive any treatment for the reported event. The clinical outcome of events menorrhagia and irregular menstrual cycle was recovered on 29Mar2021.    No follow-up attempts are needed. No further information is expected.