Age: 51.0
Sex: M
Vaccine: MMR, TDAP
Symptoms: Pain in extremity, Palpitations, Peripheral coldness, Peripheral swelling, Presyncope
Clinical narrative: Background: I took an Tdap vaccine in 2019, with no side effects. However, I experienced multiple serious side effects immediately after taking another Tdap (+ MMR) in 2021 into my left arm (both vaccines). Was very healthy prior to taking Tdap + MMR vaccines on 10/01/2021. After that date, I experienced: - chronic pain in the left chest area; physical therapy done; pain still present - chronic pain in left shoulder area; after many appointments diagnosed with left shoulder "tendinopathy" on 12/01/2022; physical therapy done which improved the function of the left shoulder/arm, however the pain is still present. - weakness of left arm+shoulder: still present but fixed 80% after physical therapy (functional improvement; however, pain still present) - tachycardia; no treatment; went away by itself in 2022 - chronic pain in the top-left-front area of skull/head/brain; no treatment; pain still ongoing - numbness of FACE (left side only; right side is okay); no treatment; symptom still ongoing - numbness of NECK (left side only; right side okay); no treatment; symptom still ongoing - brain fog; short-term memory failures; sensation of "tension" over the ocular system; constant migraine-like pain; no treatment done yet except one-time six-day course of Prednisone in 2021 which improved the condition for several weeks only; these neurological symptoms are still ongoing - tinnitus; no treatment; gone away in/around spring 2023 - swelling of both legs. Gone several months after vaccination. - inability to walk (i.e. use both legs). Left leg has mostly recovered (in ~2022), while right leg still suffers from the following issues: pain in thigh area; numbness of leg; pain in the heel area. - getting tired/fatigued quickly after any physical activity; newly developed INTOLERANCES to many types of foods and beverages (doctors said they are not "allergies" per se though) - orthostatic hypotension diagnosed/measured on 03/31/2023; no treatment so far; about to see a specialist for this condition - frequent FLARE-UPS of chronic pain, whereby the intensity of pain increases for several days over the baseline level. Occurs especially after ingesting various types of foods (note: I was able to consume any kind of food pre-vacc.), after any type of physical activity, and after experiencing stress - tremors (especially when waking up); no treatment; appears randomly & occasionally - muscle tissue "twitching" (especially in torso area); no treatment; appears randomly & occasionally - palpitations; no treatment; appears randomly & occasionally  Various diagnoses and medical opinions for all the symptoms listed above were given by medical professionals throughout 2021, 2022, and 2023, as follows (ordered from oldest to recent; most important ones only; please refer to my full medical history for a complete overview):  - 10/01/2021 I'm in "presyncopal state", but "it's not concerning" after receiving Tdap and MMR vaccines at UrgentCare - 10/02/2021 rapid worsening; beginning of anaphylactic-like reactions to common foods; for example, drinking a glass of carrot juice triggered shaking of whole body - 10/03/2021 swelling of both legs started - 10/03/2021 visit to emergency department  - 10/05/2021 onset of numbness, weakness, and coldness in legs and hands - 10/15/2021 office visit with Dr, general practitioner; all tests negative - 10/19/2021 onset of tachycardia, cramp-like pain in rear muscles (calves, back thighs) of both legs, dull headache, "stabbing" pain behind eyes, lack of coordination / disorientation / dizziness, mental "fog", feel as if I'll pass out, nausea - 10/25/2021 onset of tinnitus - 10/29/2021 mental confusion and lack of spatial awareness, fatigue, legs like lead - 10/30/2021 second visit to emergency department  - 11/14/2021 onset of acute, sharp pain in the left chest/heart area - 11/23/2021 third visit to emergency department  - 11/26/2021 office visit, Dr: "chest wall tenderness, tender and swelling lateral left pectoral area" - 12/12/2021 Emergency Department, for chest pain - 12/23/2021 office visit, Dr Cardiology, diagnosed with COSTOCHONDRITIS (chest pain). Note: dx later discarded due to long duration of pain - 01/25/2022 first day of physiotherapy (right leg) at Physiotherapy Associates; limited improvement in function observed, but no resolution of issues - 02/10/2022 sensory nerve conduction studies of lower extremities; came out negative while not ruling out "small fiber polyneuropathy" - 02/15/2022 office visit, Allergy And Asthma, MD: chest pain; "This is not allergic" - 09/12/2022 video visit with MD, Neurology. Assessment plan: "chronic RLE/L chest Pain since vaccine 10/2021. Appears to be post vaccine SE given negative rheum and neuro w/u". - 12/01/2022 orthopedic office visit with PA-C. Findings for my left shoulder: "1. Rotator cuff tendinopathy of the supraspinatus and subscapularis; no tear. 2. Mild joint capsule edema and mild ligament sprain of the acromioclavicular joint". Note: this is for my left shoulder only (right shoulder is normal). - 02/04/2023 emergency department, dizziness; tests negative - 03/21/2023 Dr Neurology, "orthostatic hypotension: possibly related to autonomic dysfunction, triggered by vaccinations." - 03/23/2023 tentatively diagnosed with CTS (central sensitization syndrome) by Dr at Clinic. - 04/17/2023 emergency Department, Emergency, for abdominal pain - 05/09/2023 staff at Neurology referred me to pain clinic - 10/20/2023 started another round of physiotherapy, both for the left shoulder/chest and right leg; physiotherapy ongoing as of time of writing (01/13/2024). Improvements of the function (but not pain levels) of my left shoulder observed; no improvements observed so far for my right leg (numbness, pain in thigh area, pain in heel area).