Age: 66.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: COVID-19, Memory impairment
Clinical narrative: Memory was not the greatest; COVID-19; This spontaneous case was reported by a consumer and describes the occurrence of MEMORY IMPAIRMENT (Memory was not the greatest) and COVID-19 (COVID-19) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.    Co-suspect products included non-company products UPADACITINIB (RINVOQ) tablet for an unknown indication and TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) for COVID-19 vaccination.    No Medical History information was reported.   On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form, UPADACITINIB (RINVOQ) (Oral) 15 milligram once a day and second dose of TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) (Intramuscular) 1 dosage form. On an unknown date, received first dose of TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced MEMORY IMPAIRMENT (Memory was not the greatest) and COVID-19 (COVID-19). At the time of the report, MEMORY IMPAIRMENT (Memory was not the greatest) outcome was unknown and COVID-19 (COVID-19) had resolved.            No concomitant medications were reported.  It was reported that the patient had Covid and had been out of commission for a while.   It was also reported that the patient was sick and was one week behind, in need of RINVOQ also stated that their memory was not the greatest. The patient had received both Covid vaccines by Pfizer and one booster by Moderna.  It was unknown if she was enrolled in a COVID-19 Vaccine Trial.   The reporter's causality for the event of COVID-19 with RINVOQ (UPADACITINIB) was a reasonable possibility and the reporter's causality for the event of sick and memory was not the greatest was not provided.  The causality with respect to PFIZER BIONTECH COVID 19 VACCINE for the event was Possible.  No treatment medications were reported.  Company comment: This spontaneous case concerns a 66-year-old female patient, with no reported medical history who experienced the unexpected, non-serious adverse event of special interest COVID-19 which occurred on an unspecified date after receiving the third dose of mRNA1273. It should be noted that the patient received 2 doses of different COVID-19 Vaccine (Pfizer Biontech) prior to the latest dose of mRNA1273. It was reported that the patient had Covid and had been out of commission for a while. It was also reported that the patient was sick and was one week behind, in need of RINVOQ she also stated that their memory was not the greatest. The clinical course and treatment details were not provided. The patient's elderly age may be considered as a risk factor for COVID-19. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 66-year-old female patient, with no reported medical history who experienced the unexpected, non-serious adverse event of special interest COVID-19 which occurred on an unspecified date after receiving the third dose of mRNA1273. It should be noted that the patient received 2 doses of different COVID-19 Vaccine (Pfizer Biontech) prior to the latest dose of mRNA1273. It was reported that the patient had Covid and had been out of commission for a while. It was also reported that the patient was sick and was one week behind, in need of RINVOQ she also stated that their memory was not the greatest. The clinical course and treatment details were not provided. The patient's elderly age may be considered as a risk factor for COVID-19. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.