Age: 78.0
Sex: M
Vaccine: FLUX
Symptoms: Computerised tomogram head normal, Echocardiogram normal, Low density lipoprotein normal, Magnetic resonance imaging head normal, Transient ischaemic attack
Clinical narrative: Transient ischemic attack; Initial information was received on 15-Dec-2023 regarding an unsolicited valid serious courtesy case received from a other health professional.  This case involves a 78 years old male patient (17.8 cm and 70.1 kg) who experienced transient ischemic attack after receiving influenza vaccine (quadrivalent).  The patient's past medical history included Aortic aneurysm from 2000 to 2012, Urinary tract infection from 30-SEP-2023 to 05-OCT-2023 and Abstains from alcohol. The patient's past medical treatment(s), vaccination(s) and family history were not provided. At the time of the event, the patient had ongoing Coronary artery disease in 2000, Chronic obstructive pulmonary disease in 2013 with grade 1, Blood cholesterol increased in 2013 with grade 1, Hypothyroidism in 2021 with grade 1, Glaucoma in 2022 with grade 1, Prostatomegaly in 2022 with grade 1, benign prostatic hpyperplasia and Hyperlipidaemia.  Concomitant medications included salbutamol sulfate (albuterol]) for chronic obstructive pulmonary disease; phytosterols nos (cholestoff original) for blood cholesterol increased; tamsulosin for benign prostatic hyperplasia; latanoprost for glaucoma; aspirin [acetylsalicylic acid], atorvastatin calcium (atorvastin) for blood cholesterol increased; and levothyroxine for hypothyroidism.  On 26-Oct-2023, the patient received a 0.5 ml dose of suspect influenza vaccine (quadrivalent) produced by unknown manufacturer (Solution for injection)  (lot number, expiry date, strength: unknown) via intramuscular route in unknown administration site for prophylactic vaccination (Immunization).  On 03-Nov-2023 the patient had transient ischemic attack (transient ischaemic attack) 8 days following the administration of influenza vaccine (quadrivalent).  Relevant laboratory test results included: Blood pressure measurement - On 26-Oct-2023:  [83/53 pre dose 122/79 post dose] Computerised tomogram - On 03-Nov-2023:  [No signs of CVA] Echocardiogram - On 26-Oct-2023:  [normal] Heart rate - On 26-Oct-2023:  [59 beats/min- pre dose 58 beats/min- post dose] Low density lipoprotein - On an unknown date:  [In the 50 s] Magnetic resonance imaging - On 03-Nov-2023:  [No signs of CVA] Physical examination - On 26-Oct-2023:  [Normal] Respiratory rate - On 26-Oct-2023:  [16-pre dose 16-post dose]  Action taken: not applicable.  It was not reported if the patient received a corrective treatment for the event.  At time of reporting, the outcome was Recovered / Resolved on 06-Nov-2023 for the event.  Seriousness Criteria: Medically significant and Hospitalization (3 days) for event transient ischemic attack.; Sender's Comments: Sanofi Company Comment dated 19-Dec-2023: This case involves a 78 years old male patient (17.8 cm and 70.1 kg) who experienced transient ischemic attack after receiving influenza vaccine (quadrivalent). The patient's past medical history included Aortic aneurysm, Urinary tract infection, Coronary artery disease, Chronic obstructive pulmonary disease, Blood cholesterol increased, Hypothyroidism, Glaucoma, Prostatomegaly, benign prostatic hpyperplasia and Hyperlipidaemia. Further information on allergy history, family history excluding alternative etiologies for the reported event are needed to fully assess this case. Based upon the limited reported information, the role of the individual suspect vaccine cannot be assessed.