Age: 88.0
Sex: M
Vaccine: COVID19
Symptoms: Epistaxis, Heart rate, Heart rate decreased, Palpitations, Respiratory failure
Clinical narrative: sometimes his lungs are not able to get enough oxygen; Rapid heart beats during the nights/heart stopped for a moment and then it started with fast heart beats; Pulse became lower, from 50 to 40; Nose bleeding; This spontaneous case was reported by a consumer and describes the occurrence of RESPIRATORY FAILURE (sometimes his lungs are not able to get enough oxygen) in an 88-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 010A21A, 032L20A and 065F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Aortic valve replacement. Previously administered products included for Product used for unknown indication: Penicillin (Had a health issue and went to the hospital, where doctors administered 9 shots of penicillin for 9 days in a row, got poisoned and and stayed at the hospital for 6 weeks) in 1954. Past adverse reactions to the above products included Drug poisoning with Penicillin. Concurrent medical conditions included Penicillin allergy (Allergy to penicillin), Borderline diabetes (Start Date: 3 or 4 years ago) and Blood pressure high (Start Date: 6 or 7 years ago). Concomitant products included LISINOPRIL for Blood pressure high, METFORMIN for Borderline diabetes, ROSUVASTATIN for Cholesterol, AMLODIPINE and ASPIRIN [ACETYLSALICYLIC ACID] for an unknown indication.   On 03-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 03-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 14-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 10-Mar-2021, the patient experienced PALPITATIONS (Rapid heart beats during the nights/heart stopped for a moment and then it started with fast heart beats), HEART RATE DECREASED (Pulse became lower, from 50 to 40) and EPISTAXIS (Nose bleeding). On an unknown date, the patient experienced RESPIRATORY FAILURE (sometimes his lungs are not able to get enough oxygen) (seriousness criterion medically significant). On 13-Mar-2021, EPISTAXIS (Nose bleeding) had resolved. At the time of the report, RESPIRATORY FAILURE (sometimes his lungs are not able to get enough oxygen), PALPITATIONS (Rapid heart beats during the nights/heart stopped for a moment and then it started with fast heart beats) and HEART RATE DECREASED (Pulse became lower, from 50 to 40) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Heart rate: 50 to 40 (Low) Pulse was low.         It was reported that after getting first dose, patient did not experienced any symptoms. After the second dose of vaccine patient started to experience rapid heartbeats during the nights, sometimes worse than others, and his pulse became lower, from 50 to 40. Patient's cardiologist monitored him for 2 weeks but could not find anything wrong, and explained to patient it could be due to sleep apnea, because sometimes his lungs are not able to get enough oxygen, then patient tried a sleep apnea mask, but it did not help to stop symptoms.   Doctor suggested a pacemaker but patient decided not to do it as patient thought there might be a possibility it may not work. Around the same time, patient had nose bleedings for 4 days, doctors changed his medication for high blood pressure, but it did not work. So the  patient visited a doctor who cauterized it, and then bleeding stopped.   Patient did not experienced new symptoms with booster dose.  Patient has no history of Myocarditis/pericarditis. Patient has never diagnosed or tested positive for COVID.  This is a spontaneous case concerning an 88-year-old male patient with a medical history of aortic valve replacement, penicillin allergy and blood pressure high, who experienced the unexpected events of respiratory failure, palpitations, heart rate decreased and epistaxis. The events palpitations, heart rate decreased and epistaxis occurred approximately 1 week  after the second dose of mRNA  1273 vaccine, while respiratory failure experienced on an unknown date. Respiratory failure is a medically significant event and at the time of report the event had not resolved. The reporter's assessment was not provided. The benefit-risk relationship of the vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning an 88-year-old male patient with a medical history of aortic valve replacement, penicillin allergy and blood pressure high, who experienced the unexpected events of respiratory failure, palpitations, heart rate decreased and epistaxis. The events palpitations, heart rate decreased and epistaxis occurred approximately 1 week  after the second dose of mRNA  1273 vaccine, while respiratory failure experienced on an unknown date. Respiratory failure is a medically significant event and at the time of report the event had not resolved. The reporter's assessment was not provided. The benefit-risk relationship of the vaccine is not affected by this report.