chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 40.0
Sex: F
Vaccine: COVID19, COVID19, COVID19, COVID19, COVID19
Symptoms: Heart rate increased, Hypertension, Hypoaesthesia, Limb discomfort, Lip swelling
Clinical narrative: 15 minutes after receiving the vaccine, she experienced numbness in her lips (felt 'swollen'). She sat 15 minutes and felt it spread. She talked to the medic, it was still present 30 minutes later. She was noted to have high blood pressure (maybe systolic BP 160-180 mm Hg with elevated HR, does not recall specifics). She was sent to the ED. The numbness over that period spread to the arm and down both legs. She had loss of dexterity in hands (could not peal the aluminum top off an orange juice cup). Mild proximal arm weakness. She was not able to walk. She was numb all over but the right was more affected. She was seen in ED that day 09MAR and later admitted. Later that night had some throat closing/gasping for air sensation. She was monitored clinically, worked with physical and occupational therapy. We chose not to perform a diagnostic LP and just monitored clinically. Work-up detailed below. Discharged hospital on 12MAR.  She gradually recovered over several weeks. She was even able to get second dose in series on 3/30/2021 (Pfizer-BioNTech Covid-19 vaccine, lot #: ER 8133, exp 7/2021). She was almost 100% about 3 weeks later. She had a similar return of the numbness and it was in her throat as well, but was immediately controlled by taking diphenhydramine OTC. She was 100% back to normal at our follow-up on 4/27/2021.
Age: 40.0
Sex: F
Vaccine: COVID19, COVID19, COVID19, COVID19, COVID19
Symptoms: Magnetic resonance imaging head, SARS-CoV-2 test, Serum ferritin, Serum ferritin decreased, Throat tightness
Clinical narrative: 15 minutes after receiving the vaccine, she experienced numbness in her lips (felt 'swollen'). She sat 15 minutes and felt it spread. She talked to the medic, it was still present 30 minutes later. She was noted to have high blood pressure (maybe systolic BP 160-180 mm Hg with elevated HR, does not recall specifics). She was sent to the ED. The numbness over that period spread to the arm and down both legs. She had loss of dexterity in hands (could not peal the aluminum top off an orange juice cup). Mild proximal arm weakness. She was not able to walk. She was numb all over but the right was more affected. She was seen in ED that day 09MAR and later admitted. Later that night had some throat closing/gasping for air sensation. She was monitored clinically, worked with physical and occupational therapy. We chose not to perform a diagnostic LP and just monitored clinically. Work-up detailed below. Discharged hospital on 12MAR.  She gradually recovered over several weeks. She was even able to get second dose in series on 3/30/2021 (Pfizer-BioNTech Covid-19 vaccine, lot #: ER 8133, exp 7/2021). She was almost 100% about 3 weeks later. She had a similar return of the numbness and it was in her throat as well, but was immediately controlled by taking diphenhydramine OTC. She was 100% back to normal at our follow-up on 4/27/2021.
Age: 31.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Computerised tomogram normal, Electrocardiogram normal, Hypoaesthesia, Laboratory test normal, Magnetic resonance imaging normal
Clinical narrative: Numbness in lower extremities
Age: 31.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Menstruation irregular, Pain, Paraesthesia, Vaginal haemorrhage
Clinical narrative: Numbness in lower extremities
Age: 31.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Hypoaesthesia
Clinical narrative: Numbness in lower extremities
Age: 56.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Death, Endotracheal intubation
Clinical narrative: Per patient's last progress note on 1/13/2021 with her medical provider was seen and treated for asthma.  Notified of death by Coroner.
Age: 56.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Death
Clinical narrative: Per patient's last progress note on 1/13/2021 with her medical provider was seen and treated for asthma.  Notified of death by Coroner.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Computerised tomogram, Electrocardiogram, Facial pain, Nausea, Neck pain
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Toothache
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Blood cholesterol, Blood pressure increased, Blood pressure measurement, Cerebrovascular accident, Facial pain
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Myocardial infarction, Nausea, Neck pain, Pain in jaw, Toothache
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Blood pressure measurement, Cerebrovascular accident, Feeling abnormal, Hypertension, Myocardial infarction
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Sex: U
Vaccine: COVID19, COVID19, COVID19
Symptoms: Nausea, Neck pain, Pain in jaw, Toothache
Clinical narrative: Entire left side of my face and left side of my neck felt like they were being jack-hammered; Entire left side of my face and left side of my neck felt like they were being jack-hammered/I have pain in my jaw and neck; Teeth on left side started to hurt/Top and bottom; Heart attack; Stroke; extremely nauseated; Normal BP of 110/65 was 204/110; I have pain in my jaw and neck; This is a spontaneous report from a contactable consumer (patient). A patient of unspecified age and gender received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Batch/Lot number was not reported), via an unspecified route of administration on 15Feb2021 as single dose for COVID-19 immunization. Medical history and concomitant medications were not reported. The patient previously received the first dose of BNT162B2 on 28Jan2021 for COVID-19 immunization. In the evening of Wednesday, 17Feb2021, it was reported that the patient's teeth on left side started to hurt. Top and bottom. At 2:00 am, Thursday, 18Feb2021, the patient called an ambulance because the entire left side of his/her face and left side of neck felt like they were being jack-hammered. The patient was extremely nauseated. His/her normal blood pressure (BP) of 110/65 was 204/110. The paramedic thought he/she was having a heart attack. Cholesterol is at 129. The patient went to the emergency room (ER) on Friday, 19Feb2021, because a doctor thought he/she was having a stroke. He/she finally went to a primary care doctor the next week, who believed the patient had a very strong antibody response so that he/she has a high level of protection. The patient reported that it took a month to get the side effects under control. Even on 11Apr2021, the patient has pain in jaw and neck that comes and goes throughout the day. The patient reported that if he/she had known that he/she would have such side effects, he/she would not have taken it. The doctor told the patient that when it is time for a booster, he wanted the patient to have a different vaccine. The outcome of the events was unknown.
Age: 59.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Asthenia, Bell's palsy, Sensory loss
Clinical narrative: GBS
Age: 59.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Blood immunoglobulin G increased, Cytomegalovirus test positive, Guillain-Barre syndrome
Clinical narrative: GBS
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Agonal respiration, Angiogram pulmonary abnormal, Areflexia, Blood lactic acid increased, Cardiac arrest
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Complication associated with device, Corneal reflex decreased, Cyanosis, Death, Device malfunction
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Disseminated intravascular coagulation, Dyspnoea, Fatigue, Intensive care, Loss of consciousness
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Lung assist device therapy, Malaise, Metabolic acidosis, Mobility decreased, Presyncope
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Pulmonary embolism, Pulseless electrical activity, Pupillary reflex impaired, Pyrexia, Respiratory acidosis
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Resuscitation, Therapy cessation, Thrombectomy, Unresponsive to stimuli, Vena cava thrombosis
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Cardiac arrest, Death, Dizziness, Dyspnoea, Hypotension
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Pulmonary embolism, SARS-CoV-2 test negative, Syncope
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Agonal respiration, Alanine aminotransferase increased, Anaemia, Anion gap, Areflexia
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Aspartate aminotransferase increased, Blood chloride normal, Blood creatinine increased, Blood gases abnormal, Blood potassium normal
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Blood sodium decreased, Blood urea normal, Brain natriuretic peptide increased, Carbon dioxide decreased, Cardiac arrest
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Chest X-ray abnormal, Coagulopathy, Continuous haemodiafiltration, Death, Dizziness
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Dyspnoea, Dyspnoea exertional, Endotracheal intubation, Full blood count, Haematocrit decreased
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.
Age: 45.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Haematoma, Haemoglobin decreased, Lactic acidosis, Livedo reticularis, Lower gastrointestinal haemorrhage
Clinical narrative: 46 year old female, presented with syncope and SOB with exertion associated with dizziness. She developed agonal breathing and PEA arrest. She was intubated and ACLS protocol was initiated. Lucas device was placed. Cath lab was contacted as well as surgical critical care attending. Decision was made to place patient on ECMO and she was transferred to the cath lab for further management. While in the cath lab, she was placed on VA ECMO via right femoral vessels. She was found to have a large saddle PE and occlusive Right PA pulmonary embolism and large clot burden in the left PA.  She underwent flow retriever with improvement in clot burden. She has significant OGT output with bloody output as well as evidence of lower GI bleed. She had a large hematoma in the left groin. She was started on epi 0.2, levo 0.3 and vaso 0.04. Vasopressin was increased to 0.08. She was resuscitated with blood products given profound anemia and coagulopathy. Her pressor requirement decreased slightly. Her neurologic exam was questionable with no movement to noxious stimuli. Her pupils were weakly reactive. She did not have a gag or cough reflex. She was breathing over the ventilator. Over the course of the next few hours, she continued to have significant pressor requirements and evidence of ongoing blood loss through her GI tract and Left  groin. She had a significant lactic acidosis that did not improve. CVVHD was initiated. Suddenly, her VA ECMO flows decreased significantly and venous pressures were high. The ECMO circuit was clamped and the venous cannula was interrogated. There was no flow from the venous cannula despite repositioning. She had evidence of mottling in her right lower extremity to her abdomen concerning for clot through the IVC. Given the suspected clot burden and lack of neurologic activity, further resuscitation was deemed futile. Family was contacted and patient was made CMO.  She subsequently expired 3/21 at 0455.