Age: 60.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Heart rate, Pericardial drainage test, SARS-CoV-2 test, Vaccination failure
Clinical narrative: pericarditis; 4 heart attacks; When he would get up to go to the bathroom his blood pressure was in the 200's; shortness of breath; chest pain; high heart rate; pressure in collar bone to diaphragm and from one side of chest; couldn't sleep all that night; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 62-year-old male patient received BNT162b2 (BNT162B2), on 12Apr2021 as dose 2, single (Lot number: ER8731) at the age of 60 years for covid-19 immunisation. The patient's relevant medical history included: "blockage" (unspecified if ongoing), notes: He had four heart attacks that was triggered by a blockage that no one knew about. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Manufacture by- Pfizer, lot number: ER2613., NDC: unknown. , Expiry: unknown.), administration date: 18Mar2021, when the patient was 60-year-old, for COVID-19 Immunization. The following information was reported: MYOCARDIAL INFARCTION (hospitalization, medically significant) with onset Apr2021, outcome "unknown", described as "4 heart attacks"; HYPERTENSION (non-serious) with onset Apr2021, outcome "unknown", described as "When he would get up to go to the bathroom his blood pressure was in the 200's"; CHEST PAIN (non-serious) with onset Apr2021, outcome "unknown"; SLEEP DISORDER (non-serious) with onset Apr2021, outcome "unknown", described as "couldn't sleep all that night"; HEART RATE INCREASED (non-serious) with onset Apr2021, outcome "unknown", described as "high heart rate"; PERICARDITIS (hospitalization, medically significant) with onset Apr2021, outcome "unknown"; CHEST DISCOMFORT (non-serious) with onset Apr2021, outcome "unknown", described as "pressure in collar bone to diaphragm and from one side of chest"; DYSPNOEA (non-serious) with onset Apr2021, outcome "recovered" (Apr2021), described as "shortness of breath". The patient was hospitalized for myocardial infarction (start date: Apr2021, discharge date: Apr2021, hospitalization duration: 10 day(s)); for pericarditis (start date: Apr2021, discharge date: Apr2021). The events "4 heart attacks" and "pericarditis" required emergency room visit. The patient underwent the following laboratory tests and procedures: Angiogram: (Apr2021) three blockages, 2 at 90% and 1 at 99%.; Blood pressure measurement: (Apr2021) 200's; Cardiac function test: (08Apr2021) didn't do great or terrible either, notes: On 08Apr2021 he had full cardiac workup and a nuclear study and stress EKG. He didn't do great or terrible either; Electrocardiogram: (08Apr2021) didn't do great or terrible either, notes: On 08Apr2021 he had full cardiac workup and a nuclear study and stress EKG. He didn't do great or terrible either; Pericardial drainage test: (Sep2021) positive for pericarditis in Sep2021; SARS-CoV-2 test: (20Apr2022) Positive, notes: A rapid test at home gave positive result. Therapeutic measures were taken as a result of myocardial infarction, pericarditis.  Clinical information: It was reported that patient got his second dose of the Pfizer COVID 19 vaccine he had a sever adverse event and ended up in the hospital for 10 days with what I heard was 4 heart attacks, he would not confirm that number with me, but states he was told it was triggered by a blockage he already had that nobody knew about, and he also ended up with pericarditis. He just tested positive for COVID on Wednesday and when he called to get something for the symptoms, he was prescribed Paxlovid. Last night when going to bed he thought to double check the active mechanism of Paxlovid and to make sure it's not the same as the MRNA to make sure he doesn't have the same thing happen. He states he has already taken it for a day, and it does not feel like he is getting pericarditis but would like to know the mechanism of action in the Paxlovid. Caller originally called with a question about Paxlovid but mentioned an adverse event with the second Covid vaccine. When he got second dose of Pfizer Covid19 vaccine he ended up in the hospital for 10 days. He had four heart attacks that was triggered by a blockage that no one knew about. He had pericarditis as well. Now he has tested positive for COVID. He is 63 years old. Agent states that the call originated from somewhere else, but agent was unable to verify from what department. Attempted to confirm details provided by transfer agent with caller. Caller states that he filled out a report with Pfizer in May2021 or Jun2021. On 08Apr2021 he had full cardiac workup and a nuclear study and stress EKG. He didn't do great or terrible either. He had the Covid vaccine on 12Apr2021 and he couldn't sleep all that night. With the first vaccine he had no problems at all. With the second one he had big problems. He normally rides his bike on Tuesday and Thursday mornings. After the vaccine, the next morning was Tuesday. He thought if he was anxious, he would just ride it off. When he got off his bike, he only made it 3 or 4 blocks and had to get home because he didn't feel right. That day and the following day, he started taking his blood pressure. When he would get up to go to the bathroom his blood pressure was in the 200's. He couldn't figure it out. He had an attack of angina suddenly. It was unlike anything he had experienced before. He thought he should go to the hospital. He thought it was different than before. That was the first event. Caller clarified that he should have said cardiac event instead of heart attacks to the agent. The cardiologist did an angiogram and he had three blockages, 2 at 90% and 1 at 99%. He had no idea. He wasn't having problems before. He had stents placed and was sent home. He was walking with his wife down the street. He walked 2 or 3 house and was coming back and he had different symptom that he had never experienced. He had shortness of breath. He tested while he was having the feeling. He could breathe just fine in and out, but it felt like his body wasn't getting oxygen. He relaxed and let things resolve. He walked back. He sat down in his comfort chair, and it happened again. Called paramedic, but it had resolved by the time the paramedic got there. He called his doctor and his doctor said to go to ER. His doctor was in the ER working. Caller is calling those two events just one because it was not fully resolved. He got in the emergency room and had another event of being out of breath. They said to schedule another angiogram to see what was going on. They did that and it was 2 to 3 days later because of staffing problems. When they transferred him to go to cath lab, he had another completely different event. He had lots of chest pain, high heart rate, they even zapped him a couple of times and he was unresponsive. That was the fourth event. That started 2 to 3 days after the second dose of vaccine. It took a little more than a week to resolve before they let him go. Caller confirms this was all reported on initial report. While he was in the hospital, he kept telling the doctors and nurses that he had pressure in collar bone to diaphragm and from one side of chest to the other. Not a lot of pressure, but uncomfortable. Everyone thought it was because caller was an old guy and was being oversensitive. The cardiologist said caller was too old to get tested for pericarditis. Caller requested pericarditis test. Caller got a new cardiologist who tested him, and caller was positive for pericarditis in Sep2021. Caller tested positive for Covid on 20Apr2022. A rapid test at home gave positive result. Caller's son had the exact same symptoms that caller does now. Caller's son had COVID before caller and caller's son had a PCR test. Now caller's granddaughter also is positive for Covid. Pericarditis was almost completely resolved by December. Caller was taking Cultrazine for pericarditis and he was able to stop that medication. The Pericarditis finally resolved. Caller is not sure if he is pronouncing the medication name correctly and doesn't know how to spell it. Medication for pericarditis spelled as pronounced by caller. Caller doesn't have NDC, lot, and expiry to provide for Cultrazine. It was reported that patient had taken two doses of Paxlovid and didn't sleep last night. He has a hard time sleeping anyway. He felt anxious. He started thinking about and wanted to know if there was connection with how the two drugs in Paxlovid and mRNA work. Caller states, it sounds like they are different, and he should be ok. He wanted to know if there were similarities in how they get absorbed and how they function in the body. He is not a doctor and needed to understand it. Caller is convinced not to get a booster and he thought if Paxlovid worked like the booster for Covid vaccine maybe he shouldn't be on Paxlovid. Caller clarified that USMI was able to assist with his questions. It doesn't sound like Paxlovid is making spike proteins.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200620164 similar report from same reporter