Sex: U
Vaccine: VARZOS
Symptoms: Joint swelling, Myalgia, Nausea, Swelling face, Weight increased
Clinical narrative: Face is puffy/Face swelling; inflammation in body; Scale shows a few pounds increase; Allergic reaction; Gout; Face inflammation; Dizziness; extreme joint pain, Knee and knuckle, Arthritic response/left ankle and right knuckles are swollen and painful; muscle pain; pounding headache; nausea; brain fog; chills; Areas were swelling, primarily knees, knuckles; Could hardly walk; This case was reported by a consumer and described the occurrence of dizziness in a patient who received Herpes zoster (Shingrix) for prophylaxis.   On 10th October 2022 16:00, the patient received the 1st dose of Shingrix. In October 2022, 18 hrs 30 min after receiving Shingrix, the patient experienced dizziness, joint pain, muscle pain, headache, nausea, foggy feeling in head, chills, swelling of knees, walking difficulty, weight gain, allergic reaction, gout and skin inflammation. On 31st October 2022, the patient experienced facial puffiness and inflammation. The patient was treated with fexofenadine hydrochloride (Allegra) and ibuprofen. On an unknown date, the outcome of the dizziness, joint pain, muscle pain, headache, nausea, foggy feeling in head, chills, swelling of knees, walking difficulty, facial puffiness, weight gain, allergic reaction, gout, skin inflammation and inflammation were recovering/resolving.   It was unknown if the reporter considered the dizziness, joint pain, muscle pain, headache, nausea, foggy feeling in head, chills, swelling of knees, walking difficulty, facial puffiness, weight gain, allergic reaction, gout, skin inflammation and inflammation to be related to Shingrix.     Additional Information: GSK Receipt Date: 31-OCT-2022 Reporter's comment: The case was self reported by the patient. The patient received first dose of Shingrix on Monday and Tuesday around 10 hours 30 minutes in am, the patient experienced dizziness, extreme joint and muscle pain, pounding headache, nausea, brain fog and chills. The patient had to take the afternoon off from work. Those symptoms began subsiding approximately 10 hours later. The patient woke up the next day with just joint pain, but nothing severe. By Friday, the patient was still experiencing joint pain and some areas were swelling, primarily his/her knees. Over that weekend, the joint pain increased as did the swelling. Right knee was by far the worst. That had continued to present day. Last Thursday, 17 days after vaccination, his/her knees were both so swollen he/she could hardly walk. Over this past weekend, the bulk of that swelling subsided dramatically. On the day of reporting, his/her left ankle and right knuckles were swollen and painful. Even his/her face was puffy and the scale showed a few pound increase which was in line with inflammation and the swelling he/she was experienced. The patient reported that the vaccine obviously caused immense inflammation in his/her body. The inflammation was triggering some sort of response in his/her body that was alarming. The patient never had anything like this before, and his/her doctor said it was almost like it has triggered an allergic reaction, gout and or an arthritic response. The patient taken allergy medicine (Allegra) at bedtime and Ibuprofen multiple times per day which assisted in minimizing symptoms, but not completely cured. The patient wanted to reach out for GlaxoSmithKline at this juncture.  The patient was quite worried with what it was done to his/her body this far. The patient obviously wondering if and when these symptoms might disappear, and asked how he/she should proceed with second dose after mid December. Additional Supportive Information: In order to capture precise time to onset, partial onset date captured.