Age: 70.0
Sex: F
Vaccine: PNC15, PPV
Symptoms: Extrasystoles, Fear, Hepatic enzyme increased, Nervousness
Clinical narrative: Feeling scared and jumpy; Feeling scared and jumpy; This was how she felt when her heart used to skip beats / her heart was skipping every 10th beat; Redness and bumps around the injection site; She also felt heavy which was abnormal for her, since she was only 120 pounds; Redness and bumps around the injection site; tiny elevation of liver enzymes; This spontaneous report was received by an 86-year-old female consumer, referring to herself.  The patient's medical history was not reported. Her concurrent conditions included mitral valve prolapse (about 18 to 20 years ago), thyroid disorder, and blood pressure high. The caller said she used to have heart palpitations and heart rate irregularity, but her symptoms had been controlled. The patient also had drug allergies to the following historical drugs: alendronate sodium (FOSAMAX), irbesartan (AVAPRO), metronidazole, and lisinopril. Concomitant medications included levothyroxine sodium (SYNTHROID), amlodipine, clonidine, propranolol, atorvastatin calcium (LIPITOR), clopidogrel bisulfate (PLAVIX) and acetylsalicylic acid (ASPIRINA).   On an unspecified date in 2008 and 2016, the patient was vaccinated with 1 dose of pneumococcal 23v polysaccharide vaccine (PNEUMOVAX 23) injection, administered intramuscularly (IM) as Pneumococcal disease prevention (strength, anatomical location, lot #, and expiration date were not provided). On an unspecified date in February 2024 (reported as a month ago), a laboratory work showed tiny elevation of liver enzymes (Hepatic enzyme increased). On 06-MAR-2024, she received the third dose of pneumococcal 23v polysaccharide vaccine (PNEUMOVAX 23) (1 dose) or the first dose of pneumococcal 15v conj vaccine (crm197) (manufacturer unknown) injection (1 dose), administered IM as Pneumococcal disease prevention (strength, anatomical location, lot #, and expiration date were not provided).  On the evening of the same date (06-MAR-2024), she was lying in bed and was feeling scared and jumpy (Fear and Nervousness), she said this was how she felt when her heart used to skip beats; the caller said she checked her pulse and her heart was skipping every 10th beat (Heartbeats skipped), furthermore, she had redness and bumps around the injection site (Vaccination site erythema and Vaccination site mass) and she also felt heavy which was abnormal for her, since she was only 120 pounds (Discomfort). The caller said she had not informed her doctor of her symptoms, but she would see the doctor next week and would have an ultrasound scheduled. The caller did not provide any further information. No treatment was administered for the events. On 07-MAR-2024, the patient recovered from the the events, the outcome of the event Hepatic enzyme increased was not provided. .   The causal relationship between the events and pneumococcal 23v polysaccharide vaccine (PNEUMOVAX 23) or pneumococcal 15v conj vaccine (crm197) (manufacturer unknown) was not reported. The causality assessment between hepatic enzyme increased and pneumococcal 15v conj vaccine (crm197) (manufacturer unknown) was considered not related as it happened previous to this vaccination.