Age: 56.0
Sex: F
Vaccine: HEP
Symptoms: Colonoscopy abnormal, Colorectal adenoma, Polypectomy
Clinical narrative: Colorectal adenoma/Tubolovillous adenoma polyp of colon; This non-serious case was reported by a nurse via other manufacturer and described the occurrence of colonic tubulovillous adenoma in a female patient who received Hepatitis B vaccine for prophylaxis.   The patient's past medical history included macular degeneration (Bilateral eyes in 2007), rotator cuff repair (in 2003 and 2005, not ongoing), visual impairment, degenerative joint disease (in 1996), appendectomy (in1959, not ongoing), lipoma (in 1990), hepatitis a (Hepatitis A experienced on 1980), ventral hernia repair (in 1981, not ongoing), knee replacement, cesarean section (3 times, not ongoing), knee replacement (in 1980 and 2003, not ongoing), joint replacement (in 1980 and 2003, not ongoing), tubal ligation (in 1980, not ongoing), anesthetic complication, pure hypercholesterolemia, carpal tunnel syndrome (Bilateral), tonsillectomy & adenoidectomy (not ongoing), carpal tunnel release (in 1988, not ongoing), knee arthroplasty (in 1980 and 2003, not ongoing), joint replacement (interphalangeal, in 2004, not ongoing), uterine dilation and curettage (in 1994, not ongoing), wheezing, shortness of breath, insomnia, phlebitis, ex-smoker (Average 1 pack/day (40.0 ttl pk-yrs),years since quitting: 8.6, Cigarette pack/day: 5), joint range of motion decreased, respiratory distress and female sterilization (in 1980). Concurrent medical conditions included type ii diabetes mellitus (without long-term current use Of insulin (HOC)), hypertension, obstructive sleep apnea (in 1995, not interested in using CPAP, uses mouth guard), pain, constipation, contact lens wearer, chronic pain (Plan followup pain specialist, upcoming injections SI joint on right, right shoulder), hyperlipidemia, shoulder pain (chronic pain in shoulder joint), osteoporosis, osteoarthritis (in 1996), seasonal allergy and environmental allergy. Concomitant products included Hepatitis b vaccine, Diphtheria vaccine toxoid, Pertussis vaccine acellular, Tetanus vaccine toxoid (Tdap), denosumab (Prolia), diphenhydramine hydrochloride (Benadryl), flaxseed oil, lisinopril dihydrate (Lisinopril), magnesium oxide, melatonin, paracetamol, tramadol hydrochloride (Ultram), duloxetine hcl, naproxen sodium (Aleve) and paracetamol (Tylenol Extra Strength).   On 14-DEC-2009, the patient received the 2nd dose of Hepatitis B vaccine. On an unknown date, an unknown time after receiving Hepatitis B vaccine, the patient experienced colonic tubulovillous adenoma (Verbatim: Colorectal adenoma/Tubolovillous adenoma polyp of colon). The outcome of the colonic tubulovillous adenoma was not reported.   It was unknown if the reporter considered the colonic tubulovillous adenoma to be related to Hepatitis B vaccine.     It was unknown if the company considered the colonic tubulovillous adenoma to be related to Hepatitis B vaccine.   Additional Information: GSK Receipt Date: 30-OCT-2024 The nurse reported that a patient received 2nd dose of Hepatitis B vaccine and experienced colorectal adenoma and tubolovillous adenoma polyp of colon in 2010. The patient received 1st dose of Hepatitis B vaccine on 13-NOV-2009 and a dose of Tdap vaccine on 09-NOV-2009 as concomitant. The colonoscopy performed and it was flexible with respect of removal of tumors, polyps or other lesions.