Age: 92.0
Sex: M
Vaccine: COVID19
Symptoms: Laboratory test, Ligament sprain, Oedema peripheral, Peripheral swelling, Polymyalgia rheumatica
Clinical narrative: polymyositis rheumatica; sprained wrist; hand got swollen; wrist got swollen; This spontaneous case was reported by a consumer and describes the occurrence of POLYMYALGIA RHEUMATICA (polymyositis rheumatica) in a 92-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 14-Mar-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In 2021, the patient experienced POLYMYALGIA RHEUMATICA (polymyositis rheumatica) (seriousness criterion medically significant), LIGAMENT SPRAIN (sprained wrist), PERIPHERAL SWELLING (hand got swollen) and OEDEMA PERIPHERAL (wrist got swollen). The patient was treated with PREDNISONE for Adverse event, at an unspecified dose and frequency. At the time of the report, POLYMYALGIA RHEUMATICA (polymyositis rheumatica) and LIGAMENT SPRAIN (sprained wrist) outcome was unknown and PERIPHERAL SWELLING (hand got swollen) and OEDEMA PERIPHERAL (wrist got swollen) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Laboratory test: abnormal (abnormal) inflammatory markers resulted to be elevated.. In 2021, X-ray: no broken wrist (normal) No broken wrist.         The event happened 2 or 3 weeks after the second dose. Patient went to the rheumatologist, they did X-ray and he did not have a broken wrist; they did lab work and inflammatory markers resulted to be elevated. No concomitant medication were provided.  Company Comment: This case concerns a  92-year-old, male patient with no relevant medical history, who experienced the unexpected event of Polymyalgia Rheumatica. The event occurred approximately 2-3 weeks after the second dose of mRNA-1273 (Moderna Covid-19 vaccine). Patient bent over and sprained his wrist; hand and wrist got swollen afterwards. X-ray didn't revealed any broken wrist, but laboratory work revealed elevated inflammatory markers with a diagnosis of polymyalgia rheumatica. The rechallenge was unknown since no information about the first dose was disclosed. In this case, patient's advanced age remains a confounder. The benefit-risk relationship of mRNA-1273 (Moderna Covid-19 vaccine) is not affected by this report.; Sender's Comments: This case concerns a  92-year-old, male patient with no relevant medical history, who experienced the unexpected event of Polymyalgia Rheumatica. The event occurred approximately 2-3 weeks after the second dose of mRNA-1273 (Moderna Covid-19 vaccine). Patient bent over and sprained his wrist; hand and wrist got swollen afterwards. X-ray didn't revealed any broken wrist, but laboratory work revealed elevated inflammatory markers with a diagnosis of polymyalgia rheumatica. The rechallenge was unknown since no information about the first dose was disclosed. In this case, patient's advanced age remains a confounder. The benefit-risk relationship of mRNA-1273 (Moderna Covid-19 vaccine) is not affected by this report.