Age: 90.0
Sex: F
Vaccine: COVID19
Symptoms: Arthritis, Grip strength decreased, Joint stiffness, Pain in extremity, Paraesthesia
Clinical narrative: Has preexisting arthritis and her hands have tendency to curl up, feels tightness around ankles and toes will curl under at night(Original symptoms returned after booster); Says at night her hands and feet curl  legs get stiff at night/tightness around the ankel(Original symptoms returned after booster)/my legs, ankles and feet down to my toes would feel stiff; toes feel swollen but are not(Original symptoms returned after booster)/ big toes curled up -felt strange and swollen; toes felt "prickly"(Original symptoms returned after booster); between the toes felt "prickly" they hurt, hands ache(Original symptoms returned after booster); Hand swelling(Original symptoms returned after booster); My grasp is much less(Original symptoms returned after booster); This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (Has preexisting arthritis and her hands have tendency to curl up, feels tightness around ankles and toes will curl under at night(Original symptoms returned after booster)), JOINT STIFFNESS (Says at night her hands and feet curl  legs get stiff at night/tightness around the ankel(Original symptoms returned after booster)/my legs, ankles and feet down to my toes would feel stiff), SWELLING (toes feel swollen but are not(Original symptoms returned after booster)/ big toes curled up -felt strange and swollen), PARAESTHESIA (toes felt "prickly"(Original symptoms returned after booster)) and PAIN IN EXTREMITY (between the toes felt "prickly" they hurt, hands ache(Original symptoms returned after booster)) in a 90-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Atrial fibrillation (started years ago), Hypothyroidism (started years ago), Coagulation disorder and Arthritis (experienced for few fingers). Concomitant products included APIXABAN (ELIQUIS) for Coagulation disorder, LEVOTHYROXINE for Hypothyroidism.    On 29-Nov-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Dec-2021, the patient experienced ARTHRITIS (Has preexisting arthritis and her hands have tendency to curl up, feels tightness around ankles and toes will curl under at night(Original symptoms returned after booster)), JOINT STIFFNESS (Says at night her hands and feet curl  legs get stiff at night/tightness around the ankel(Original symptoms returned after booster)/my legs, ankles and feet down to my toes would feel stiff), SWELLING (toes feel swollen but are not(Original symptoms returned after booster)/ big toes curled up -felt strange and swollen), PARAESTHESIA (toes felt "prickly"(Original symptoms returned after booster)), PAIN IN EXTREMITY (between the toes felt "prickly" they hurt, hands ache(Original symptoms returned after booster)), PERIPHERAL SWELLING (Hand swelling(Original symptoms returned after booster)) and GRIP STRENGTH DECREASED (My grasp is much less(Original symptoms returned after booster)). At the time of the report, ARTHRITIS (Has preexisting arthritis and her hands have tendency to curl up, feels tightness around ankles and toes will curl under at night(Original symptoms returned after booster)), JOINT STIFFNESS (Says at night her hands and feet curl  legs get stiff at night/tightness around the ankel(Original symptoms returned after booster)/my legs, ankles and feet down to my toes would feel stiff), SWELLING (toes feel swollen but are not(Original symptoms returned after booster)/ big toes curled up -felt strange and swollen), PARAESTHESIA (toes felt "prickly"(Original symptoms returned after booster)), PAIN IN EXTREMITY (between the toes felt "prickly" they hurt, hands ache(Original symptoms returned after booster)), PERIPHERAL SWELLING (Hand swelling(Original symptoms returned after booster)) and GRIP STRENGTH DECREASED (My grasp is much less(Original symptoms returned after booster)) had not resolved.            The patient's concomitants included daily oral vitamins. At the time of vaccination initial problems had slowly abated but was still very uncomfortable. The two nights later from vaccination the patient again experienced all adverse events. The patient did not seek medical care.  Company comment: This case concerns a 90-year-old, female patient, with medical history of Arthritis, who experienced the non-serious, unexpected events of Arthritis (ADR), joint stiffness, swelling,  paresthesia, pain in extremity, peripheral swelling, and grip strength decreased. The events occurred  2 days after third dose of mRNA 1273 vaccine. The patient experienced the same effect after the second dose, which somewhat abated prior to the booster, but was still uncomfortable.  Then 2 nights after the booster, patient felt the symptoms but less forceful than the second shot, and 3 nights after the booster, the symptoms was same intensity as after the second shot. The patient's age and current illness of arthritis remain as confounders to the events. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.   This case was linked to MOD-2021-378765 (Patient Link).; Sender's Comments: This case concerns a 90-year-old, female patient, with medical history of Arthritis, who experienced the non-serious, unexpected events of Arthritis (ADR), joint stiffness, swelling,  paresthesia, pain in extremity, peripheral swelling, and grip strength decreased. The events occurred  2 days after third dose of mRNA 1273 vaccine. The patient experienced the same effect after the second dose, which somewhat abated prior to the booster, but was still uncomfortable.  Then 2 nights after the booster, patient felt the symptoms but less forceful than the second shot, and 3 nights after the booster, the symptoms was same intensity as after the second shot. The patient's age and current illness of arthritis remain as confounders to the events. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.