Age: 69.0
Sex: M
Vaccine: COVID19
Symptoms: Biopsy lung, Dyspnoea, Pneumothorax
Clinical narrative: Pneumothorax; Difficulty breathing; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PNEUMOTHORAX (Pneumothorax) and DYSPNOEA (Difficulty breathing) in a 69-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Squamous cell carcinoma in June 2018, GERD, BPH since an unknown date, COPD since an unknown date, Hyperlipidemia, Nicotine addiction and Lobectomy (thyroid) in 2019. Concurrent medical conditions included Lung cancer stage IV since July 2019. Concomitant products included Pembrolizumab for Lung cancer stage IV, GABAPENTIN (NEURONTIN) from 01-Jan-2009 to an unknown date, ATORVASTATIN from 01-Dec-2015 to an unknown date, MEGESTROL from 01-Jan-2009 to an unknown date, TAMSULOSIN from 01-Jan-2009 to an unknown date, PANTOPRAZOLE from 01-Dec-2015 to an unknown date and TRAZODONE from 01-Jan-2020 to an unknown date for an unknown indication.   On 30-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 ml. On 28-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 ml. On 10-Jun-2021, the patient experienced PNEUMOTHORAX (Pneumothorax) (seriousness criteria hospitalization prolonged and medically significant) and DYSPNOEA (Difficulty breathing) (seriousness criterion hospitalization prolonged). The patient was hospitalized from 10-Jun-2021 to 17-Jun-2021 due to DYSPNOEA and PNEUMOTHORAX. The patient was treated with TIOTROPIUM BROMIDE MONOHYDRATE (SPIRIVA) ongoing from 17-Jun-2021 at an unspecified dose and frequency; SALBUTAMOL (ALBUTEROL HFA) ongoing from 17-Jun-2021 at an unspecified dose and frequency and Surgery (thoracoscopic surgery with wedge resection for right pneumothorax) for Pneumothorax. At the time of the report, PNEUMOTHORAX (Pneumothorax) and DYSPNOEA (Difficulty breathing) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 16-Jun-2021, Biopsy lung: unknown (abnormal) lung biopsy video assisted thoracoscopic surgery with wedge resection for right pneumothorax.         The patient has been on treatment for stage 4 lung cancer.  Post taking the vaccine, the patient experienced difficulty breathing and was hospitalized. Surgery was performed and later patient was discharged. Is recovering well and reporter believes this is related to the lung cancer.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However, the medical history of Squamous cell carcinoma, COPD and Nicotine addiction could be a contributory factor.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However, the medical history of Squamous cell carcinoma, COPD and Nicotine addiction could be a contributory factor.