Age: 65.0
Sex: M
Vaccine: VARZOS
Symptoms: Gait inability, Hypersensitivity, Immediate post-injection reaction, Lip swelling, Movement disorder
Clinical narrative: This case was reported by a consumer via call center representative and described the occurrence of vestibular neuronitis in a 65-year-old male patient who received SHINGRIX for prophylaxis. On 30th October 2018, the patient received the 1st dose of SHINGRIX. On 30th October 2018, immediately after receiving SHINGRIX, the patient experienced allergic reaction, ear pruritus and lip swelling. On 31st October 2018, the patient experienced vestibular neuronitis, spinning sensation and dizziness. On 1st November 2018, the patient experienced speech disorder, movement disorder and fall. On 18th January 2019, the patient experienced difficulty in standing and unable to walk. On an unknown date, the patient experienced feeling cold. The patient was treated with fexofenadine hydrochloride (Allegra). On an unknown date, the outcome of the vestibular neuronitis, dizziness and feeling cold were not recovered/not resolved and the outcome of the spinning sensation and allergic reaction were unknown and the outcome of the speech disorder, difficulty in standing, movement disorder, ear pruritus, lip swelling, unable to walk and fall were recovered/resolved. The reporter considered the vestibular neuronitis, spinning sensation, allergic reaction, dizziness, feeling cold, speech disorder, difficulty in standing, movement disorder, ear pruritus, lip swelling, unable to walk and fall to be related to SHINGRIX. Additional details were reported as follows: The patient stated that immediately after receiving SHINGRIX in the left arm, he experienced an allergic reaction that included itchy ears and swollen lips. The patient stated that he took some Allegra and that seemed to resolve the symptoms. The patient stated that the next day, on 31st October 2018, 1 day after vaccination, when he woke up, he was dizzy and later that day experienced the severe dizziness and was not able to drive. The patient stated that he took a nap and the next day, on 1st November 2018, 2 days after vaccination, he experienced the room spinning, trouble speaking, and could not move his arms. The patient stated that he collapsed and had to go to the emergency room. The patient was referred to an ear nose throat (ENT) who diagnosed him with vestibular neuritis and vertigo. The ENT doctor believed that the vestibular neuritis was caused by the SHINGRIX vaccine. The patient stated that his doctor advised him not to get the 2nd dose and referred the patient to a physical therapist. The patient stated that he was getting better and then on 18th January 2019, 80 days after vaccination, the dizziness started again and the vertigo was so bad that he could not walk or stand and was now back in physical therapy. Less than year after vaccination, the patient experienced feeling cold. The patient stated that he also feels cold all of the time and did not experience feeling cold before he received the SHINGRIX vaccine. The patient stated that he could only look at the computer for 10 to 15 minutes and then he would get dizzy. The reporter consented to follow up.