Age: 83.0
Sex: M
Vaccine: COVID19
Symptoms: Abdominal pain, Constipation, Decreased appetite, Gallbladder disorder, Intestinal ischaemia
Clinical narrative: Mesenteric ischemia; gallbladder healing; constipation; Abdominal pain; Nausea; no appetite; anything he eats he throws up and vomiting; in three months he has lost 50 lbs; This spontaneous case was reported by an other health care professional and describes the occurrence of INTESTINAL ISCHAEMIA (Mesenteric ischemia), GALLBLADDER DISORDER (gallbladder healing), CONSTIPATION (constipation), ABDOMINAL PAIN (Abdominal pain), NAUSEA (Nausea), DECREASED APPETITE (no appetite), VOMITING (anything he eats he throws up and vomiting) and WEIGHT DECREASED (in three months he has lost 50 lbs) in an 83-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Gallbladder removal.   In June 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In July 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced INTESTINAL ISCHAEMIA (Mesenteric ischemia) (seriousness criteria hospitalization and medically significant), GALLBLADDER DISORDER (gallbladder healing) (seriousness criterion hospitalization), CONSTIPATION (constipation) (seriousness criterion hospitalization), ABDOMINAL PAIN (Abdominal pain) (seriousness criterion hospitalization), NAUSEA (Nausea) (seriousness criterion hospitalization), DECREASED APPETITE (no appetite) (seriousness criterion hospitalization), VOMITING (anything he eats he throws up and vomiting) (seriousness criterion hospitalization) and WEIGHT DECREASED (in three months he has lost 50 lbs) (seriousness criterion hospitalization). The patient was hospitalized on 05-Aug-2021 due to ABDOMINAL PAIN, DECREASED APPETITE, GALLBLADDER DISORDER, INTESTINAL ISCHAEMIA, NAUSEA, VOMITING and WEIGHT DECREASED, and then on 11-Aug-2021 due to CONSTIPATION. The patient was treated with ASCORBIC ACID, ERGOCALCIFEROL, NICOTINAMIDE, RETINOL, RIBOFLAVIN, THIAMINE HYDROCHLORIDE (VITAMINS [ASCORBIC ACID;ERGOCALCIFEROL;NICOTINAMIDE;RETINOL;RIBOFLAVIN;THIAMINE HYDROCHLORIDE]) at an unspecified dose and frequency and ONDANSETRON (ZOFRAN [ONDANSETRON]) at an unspecified dose and frequency. At the time of the report, INTESTINAL ISCHAEMIA (Mesenteric ischemia), GALLBLADDER DISORDER (gallbladder healing), CONSTIPATION (constipation), ABDOMINAL PAIN (Abdominal pain), NAUSEA (Nausea), DECREASED APPETITE (no appetite), VOMITING (anything he eats he throws up and vomiting) and WEIGHT DECREASED (in three months he has lost 50 lbs) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medication was not provided Treatment medication included vitamins  company comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. More information has been requested.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. More information has been requested.