Age: 14.0
Sex: F
Vaccine: HPV4
Symptoms: Fatigue, Headache, Hot flush, Impaired work ability, Loss of personal independence in daily activities
Clinical narrative: Postural Orthostatic Tachycardia Syndrome/autonomic injuries/blacked out and would often feel racing/headaches, fatigue, dizziness, faintness to the point of feeling like she was going to pass out, heart palpitations, hot flashes, brain fog, SOB; circadian rhythm sleep disorder; tunnel vision; Neurological injuries/Tingling sensation; autoimmune injuries; Information has been received regarding a case in litigation from a lawyer concerning an adult female patient (pt). The pt medical history, concurrent conditions, concomitant medications and previous drug reactions, or allergies were not reported. On an unknown date, at 14 years old, the pt was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (dose, strength, vaccination scheme, route of administration, anatomical location, lot number and expiration date were not provided). Then, on an unspecified date, at 15 years old, she was vaccinated with the second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (dose, strength, vaccination scheme, route of administration, anatomical location, lot number and expiration date were not provided), both doses were administered under the with the pt's mother consent, as preventing cervical cancer. On an unspecified date, after the first vaccination with the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)), the pt blacked out and would often feel her heart racing. Thereafter, on an unspecified date, after the second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), she developed headaches, fatigue, tingling sensations, dizziness, faintness to the point of feeling like she was going to pass out, heart palpitations, hot flashes, brain fog, tunnel vision, and shortness of breath (SOB). As the months progressed, so did her symptoms, as on unspecified dates, she was seen by multiple physicians and specialist for her complains which included a postural orthostatic tachycardia syndrome ("POTS") diagnosed by her neurologist. Likewise, the pt sustained serious autoimmune, autonomic, and neurological injuries as a result. Due to her post- quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, she had been unable to engage in activities that a normal young person would enjoy, as her symptoms made it difficult for her to attend school regularly, play in the orchestras, perform in musicals, work a job, or volunteer at church. Also, she had to withdraw from college for a period of time because she was unable to attend classes due to her condition. Based upon her chronic and severe post- quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt had been diagnosed with various medical conditions, including but not limited to POTS, circadian rhythm sleep disorder and daytime fatigue.  As a proximate result of company's wrongful acts and omissions and its negligent and fraudulent testing, labeling, manufacturing, marketing and promotion of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), the pt had suffered and continued to suffer severe and permanent physical injuries, and associated symptomology and had suffered severe and permanent physical injuries, including pain and suffering, she also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) induced injuries, the pt had suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity. At the time of reporting, the pt had not recovered from the events. The reporter considered all the aforementioned events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL).  All the events were considered disabling by the reporter.  Upon internal review, the event autoimmune disorder and tunnel vision were determined to be medically significant.