Age: 51.0
Sex: F
Vaccine: COVID19, UNK
Symptoms: Carpal tunnel syndrome, Inappropriate schedule of product administration, Neck pain, Nephrolithiasis, Pain in extremity
Clinical narrative: Drug effect decreased/ Did not feel like humira was working after getting Covid-19 vaccine; neck pain; Carpal tunnel syndrome; pain in hand; Rash aggravated/ More breakout than normally in legs and arms; Patient received first dose of Moderna on 10-Aug-2021, second dose on 15-Sep-2021 and third booster dose on 15-Jan-2022; Kidney stones; This spontaneous case was reported by a consumer and describes the occurrence of NEPHROLITHIASIS (Kidney stones), THERAPEUTIC PRODUCT EFFECT DECREASED (Drug effect decreased/ Did not feel like humira was working after getting Covid-19 vaccine), NECK PAIN (neck pain), CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome) and PAIN IN EXTREMITY (pain in hand) in a 49-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) solution for injection for Plaque psoriasis.    Patient had no known allergies.  Concurrent medical conditions included Plaque psoriasis.   On 10-Aug-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 15-Sep-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 15-Jan-2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) citrate free. On 15-Mar-2020, the patient experienced NEPHROLITHIASIS (Kidney stones). On 15-Sep-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient received first dose of Moderna on 10-Aug-2021, second dose on 15-Sep-2021 and third booster dose on 15-Jan-2022). On an unknown date, the patient experienced THERAPEUTIC PRODUCT EFFECT DECREASED (Drug effect decreased/ Did not feel like humira was working after getting Covid-19 vaccine), NECK PAIN (neck pain), CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome), PAIN IN EXTREMITY (pain in hand) and RASH (Rash aggravated/ More breakout than normally in legs and arms). At the time of the report, NEPHROLITHIASIS (Kidney stones), CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome) and INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient received first dose of Moderna on 10-Aug-2021, second dose on 15-Sep-2021 and third booster dose on 15-Jan-2022) outcome was unknown and THERAPEUTIC PRODUCT EFFECT DECREASED (Drug effect decreased/ Did not feel like Humira was working after getting Covid-19 vaccine), NECK PAIN (neck pain), PAIN IN EXTREMITY (pain in hand) and RASH (Rash aggravated/ More breakout than normally in legs and arms) had not resolved. Concomitant product use was not provided by the reporter.  It was unknown if patient was enrolled in a COVID-19 Vaccine Trial.  Causality for HUMIRA (ADALIMUMAB): The reporter's causality for the events of Kidney stones, Drug effect decreased/ Did not feel like Humira was working after getting Covid-19 vaccine, neck pain, Carpal tunnel syndrome, pain in hand and Rash aggravated/ More breakout than normally in legs and arms was not reported.  No treatment information reported.