Age: 41.0
Sex: F
Vaccine: COVID19
Symptoms: Chest pain, Dyspnoea, Hyperhidrosis, Pyrexia, Seizure
Clinical narrative: constant seizures which lasted for 1.5 hours; chest pain; trouble breathing; body was very hot and sweaty due to fever; body was very hot and sweaty due to fever; This spontaneous case was reported by a consumer and describes the occurrence of SEIZURE (constant seizures which lasted for 1.5 hours) in a 41-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 007B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Asthma.    In September 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In September 2021, the patient experienced SEIZURE (constant seizures which lasted for 1.5 hours) (seriousness criterion medically significant), CHEST PAIN (chest pain), DYSPNOEA (trouble breathing), HYPERHIDROSIS (body was very hot and sweaty due to fever) and PYREXIA (body was very hot and sweaty due to fever). The patient was treated with OXYGEN for Adverse event, at an unspecified dose and frequency. In September 2021, SEIZURE (constant seizures which lasted for 1.5 hours) had resolved. At the time of the report, CHEST PAIN (chest pain), DYSPNOEA (trouble breathing), HYPERHIDROSIS (body was very hot and sweaty due to fever) and PYREXIA (body was very hot and sweaty due to fever) outcome was unknown.            Treatment medications were not reported. Concomitant medications were not reported. The reporter stated that the patient received the 2nd dose of Moderna vaccine last week and had immediate reaction. Within a minute following vaccination and patient developed constant seizures which lasted for 1.5 hours and chest pain, trouble in breathing and patient body was very hot and sweaty due to fever and they put icepack all over patient body. Patient was seen by 3 doctors and nurses at the clinic, but patient refused to go to Emergency room for further monitoring. Patient was on oxygen and monitored patient vitals, Patient contacted her HCP and was told could not be seen until 14 days because she was shedding or has COVID-19 and patient uses nebulizer and inhaler PRN for asthma.  This case concerns a 41-year-old female patient with concurrent medical condition of asthma, who experienced unexpected events of seizure, chest pain and dyspnoea. It was reported that the events occurred within a minute following the second dose of mRNA-1273. The rechallenge was unknown since no information about the first dose was disclosed. Concurrent medical conditions of asthma remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This case concerns a 41-year-old female patient with concurrent medical condition of asthma, who experienced unexpected events of seizure, chest pain and dyspnoea. It was reported that the events occurred within a minute following the second dose of mRNA-1273. The rechallenge was unknown since no information about the first dose was disclosed. Concurrent medical conditions of asthma remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.