Age: 75.0
Sex: F
Vaccine: RSV, FLUX, PNC20, RVX, UNK
Symptoms: Chest pain, Dyspnoea, Hypersensitivity, Oropharyngeal pain, Swelling face
Clinical narrative: chest pain; trouble breathing; allergic reaction; throat hurts; face swelled up from her eyes to her throat; This spontaneous case was reported by a patient and describes the occurrence of SWELLING FACE (face swelled up from her eyes to her throat), CHEST PAIN (chest pain), DYSPNOEA (trouble breathing), HYPERSENSITIVITY (allergic reaction) and OROPHARYNGEAL PAIN (throat hurts) in a 75-year-old female patient who received mRNA-1273.815 (SPIKEVAX 2023-2024 PFS) (batch no. 210F23A) for COVID-19 prophylaxis.    Co-suspect products included non-company products PNEUMOCOCCAL VACCINE CONJ 20V (CRM197) (PREVNAR 20) for an unknown indication, INFLUENZA VACCINE for an unknown indication and RSV VACCINE for an unknown indication.    Previously administered products included for COVID-19 prophylaxis: Pfizer (Dose 1) on 09-Feb-2021, Pfizer (Dose 2) on 02-Mar-2021, Pfizer (Dose 3, she received the monoclonal antibody IV therapy.) on 18-Aug-2021, Pfizer (Dose 4 and GJ3274) on 12-Nov-2022; for Product used for unknown indication: Prevnar 20, Influenza and RSV. Past adverse reactions to the above products included COVID-19 with Pfizer; and No adverse event with Influenza, Pfizer, Pfizer, Pfizer, Prevnar 20 and RSV. Concurrent medical conditions included Drug allergy, Drug allergy, Drug allergy, Allergy, Drug allergy, Drug allergy, Drug allergy and Drug allergy (She had bronchospasms and chest pains from it.).   On 25-Oct-2023, the patient received fifth dose of mRNA-1273.815 (SPIKEVAX 2023-2024 PFS) (Intramuscular use) 1 dosage form and dose of INFLUENZA VACCINE (unknown route) 1 dosage form. On 26-Oct-2023, the patient received dose of PNEUMOCOCCAL VACCINE CONJ 20V (CRM197) (PREVNAR 20) (unknown route) 1 dosage form and dose of RSV VACCINE (unknown route) 1 dosage form. In October 2023, the patient experienced SWELLING FACE (face swelled up from her eyes to her throat), DYSPNOEA (trouble breathing), HYPERSENSITIVITY (allergic reaction) and OROPHARYNGEAL PAIN (throat hurts). On 31-Oct-2023, the patient experienced CHEST PAIN (chest pain). The patient was treated with ADRENALINE [EPINEPHRINE] on 31-Oct-2023 at an unspecified dose and frequency and METHYLPREDNISOLONE SODIUM SUCCINATE (SOLUMEDROL) at an unspecified dose and frequency. At the time of the report, SWELLING FACE (face swelled up from her eyes to her throat), CHEST PAIN (chest pain) and HYPERSENSITIVITY (allergic reaction) had not resolved and DYSPNOEA (trouble breathing) and OROPHARYNGEAL PAIN (throat hurts) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Heart rate: 82. On an unknown date, Oxygenation index: was 75 but it came back up to 98..     For mRNA-1273.815 (SPIKEVAX 2023-2024 PFS) (Intramuscular use), the reporter did not provide any causality assessments.   Patient received Spikevax on 25OCT2023 and then she also received the influenza vaccine at the same time. On 26 OCT 2023 she received the RSV and Prevnar 20 vaccinations. On 31 Oct 2023, she went to the emergency room because her face swelled up from her eyes to her throat. She had trouble breathing. She had an allergic reaction to it. The emergency room doctor walked in and stated, "that is impressive swelling". She had some chest pain in the emergency room where they gave her adrenaline. Solumedrol was given to her for at home care.   She is unsure if it is a combination of all of these vaccinations or the gentamicin in the RSV vaccination. She got the RSV vaccination at Sam's club so she let the pharmacist know that she was allergic to it but they gave it to her anyways. Today her face is still swollen, it hurts and her throat hurts, her pulse was 82. She took her inhaler and is on at home oxygen at 6 liters. Her oxygen level was 75 but it cam back up to 98.