Age: 73.0
Sex: F
Vaccine: COVID19
Symptoms: Tremor
Clinical narrative: Feel like there's a jolt & wake up to see that it's her lower extremities making the bed move/ For her hands & arms, she just hold them until they quit; She get this feeling in her head & can't remember what she was saying/ her clear thinking is what's really bothering her; She see what she was trying to say, but she can't speak it/ she try to tell people something & she can't get it out; Her mouth starts getting numb; She think it's messed up Her whole body/ she was scared; Her legs wouldn't walk/ needed help going to the bathroom; Her legs wouldn't move; Tremors in her hands, arms, & legs/ can't make them stop/ Right now her right arm & hand is shaking; Slurred speech; She stuttered; Her conditions are getting worse; This spontaneous case was reported by a consumer and describes the occurrence of GAIT INABILITY (Her legs wouldn't walk/ needed help going to the bathroom) and HYPOKINESIA (Her legs wouldn't move) in a 73-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 0271-121B, 016M20A and 011J20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 22-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 17-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 04-Jan-2021, the patient experienced CONDITION AGGRAVATED (Her conditions are getting worse). On 19-Dec-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced GAIT INABILITY (Her legs wouldn't walk/ needed help going to the bathroom) (seriousness criterion disability), HYPOKINESIA (Her legs wouldn't move) (seriousness criterion disability), TREMOR (Tremors in her hands, arms, & legs/ can't make them stop/ Right now her right arm & hand is shaking), DYSARTHRIA (Slurred speech) and DYSPHEMIA (She stuttered). On 04-Jan-2022, the patient experienced DYSKINESIA (Feel like there's a jolt & wake up to see that it's her lower extremities making the bed move/ For her hands & arms, she just hold them until they quit). 04-Jan-2022, the patient experienced MEMORY IMPAIRMENT (She get this feeling in her head & can't remember what she was saying/ her clear thinking is what's really bothering her), APHASIA (She see what she was trying to say, but she can't speak it/ she try to tell people something & she can't get it out), HYPOAESTHESIA ORAL (Her mouth starts getting numb) and FEELING ABNORMAL (She think it's messed up Her whole body/ she was scared). At the time of the report, GAIT INABILITY (Her legs wouldn't walk/ needed help going to the bathroom), HYPOKINESIA (Her legs wouldn't move), TREMOR (Tremors in her hands, arms, & legs/ can't make them stop/ Right now her right arm & hand is shaking), DYSARTHRIA (Slurred speech), DYSPHEMIA (She stuttered), DYSKINESIA (Feel like there's a jolt & wake up to see that it's her lower extremities making the bed move/ For her hands & arms, she just hold them until they quit), MEMORY IMPAIRMENT (She get this feeling in her head & can't remember what she was saying/ her clear thinking is what's really bothering her), APHASIA (She see what she was trying to say, but she can't speak it/ she try to tell people something & she can't get it out), HYPOAESTHESIA ORAL (Her mouth starts getting numb), FEELING ABNORMAL (She think it's messed up Her whole body/ she was scared) and CONDITION AGGRAVATED (Her conditions are getting worse) had not resolved.            No concomitant medications were provided.  No treatment medications were reported.  The patient is usually an active person. She take long hikes with her daughter, & she kayak. Company Comment:  This case concerns a 73-year-old, female patient with no relevant medical history, who experienced the unexpected serious events of Gait Inability, Hypokinesia, Tremor, Dysarthria, Dysphemia, Dyskinesia, Memory Impairment, Aphasia, Hypoesthesia, Feeling Abnormal, and Condition Agrravated. The events of gait inability, hypokinesia, tremor, dysarthria, and dysphemia occurred approximately 2 days after the third dose of mRNA-1273 (Moderna covid-19 vaccine); while dyskinesia, memory impairment, aphasia, hypoesthesia, feeling abnormal, and condition aggravated occurred 18 days after the third dose. The rechallenge was not applicable as events occurred after third dose. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.   This case was linked to MOD-2022-438710, MOD-2022-438711 (Patient Link).; Sender's Comments: This case concerns a 73-year-old, female patient with no relevant medical history, who experienced the unexpected serious events of Gait Inability, Hypokinesia, Tremor, Dysarthria, Dysphemia, Dyskinesia, Memory Impairment, Aphasia, Hypoesthesia, Feeling Abnormal, and Condition Agrravated. The events of gait inability, hypokinesia, tremor, dysarthria, and dysphemia occurred approximately 2 days after the third dose of mRNA-1273 (Moderna covid-19 vaccine); while dyskinesia, memory impairment, aphasia, hypoesthesia, feeling abnormal, and condition aggravated occurred 18 days after the third dose. The rechallenge was not applicable as events occurred after third dose. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.