Age: 11.0
Sex: F
Vaccine: HPV4
Symptoms: Headache, Heart rate increased, Impaired work ability, Insomnia, Loss of personal independence in daily activities
Clinical narrative: conversion disorder with seizures/uncontrollable seizures resulting in multiple hosp./ tiredness/weakness/severe headache/extreme pain/neurological injuries; Sydenham's chorea/tics/autoimmune injuries/; rapid heart rate/elevated heart rate; elevated blood pressure; weight loss; loss of appetite; urinary incontinence; insomnia; autonomic injuries; Information has been received from a lawyer regarding a case in litigation and refers to a female patient (pt) whose exact age/age group at the time of events could not be established unequivocally but who was an adult at the time of report. The pt's concurrent conditions, medical history and concomitant therapies were not provided. Before receiving quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), the pt was healthy, happy, and energetic. She enjoyed school, being on the school drumline, and was preparing for program once in high school as her desire was to continue upon completion of high school. On 17-MAR-2016, when the patient was 11 years old, she was vaccinated with the first dose (two doses in total) of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (dose, lot #, expiration date, route of administration and anatomical location were not provided for any of administered doses) for prophylaxis (reported as "touted as a safe and effective vaccine for preventing cervical cancer"), as recommended by the pt's physician and consented by the pt's mother. On unknown dates, the patient experienced serious autoimmune, autonomic, and neurological injuries as a result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections. As the months progressed, so did the patient's injuries. She was seen by multiple physicians and specialists for her complaints of severe headaches, elevated heart rate and blood pressure, tics, tiredness, weakness, weight loss, loss of appetite, urinary incontinence, insomnia, and extreme pain. She began to experience uncontrollable seizures multiple times per day resulting in multiple hospitalizations. As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, she  was unable to engage in activities that a normal young person would enjoy. Due to frequent seizures, tics, and a rapid heart rate, she missed a significant amount of school and could no longer attend school in person and switched to homeschooling, which proved to be challenging. Despite these difficulties, she persevered and successfully earned her high school diploma. The patient was unable to sustain gainful employment due to her debilitating medical conditions. Based upon her chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, she was diagnosed with various medical conditions, including but not limited to, conversion disorder with seizures, and Sydenham's chorea. As a proximate result of the suspect vaccination, the patient suffered and continued to suffer severe and permanent physical injuries, and associated symptomology and suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) - induced injuries, she suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity and she would continue to incur these losses and expenses in the future. The outcome of the events was considered to be not recovered/not resolved. The reporter considered all the events to be related to human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL).  Upon internal review, the events of Sydenham's chorea and autonomic injuries were determined to be medically significant. The reporter considered all events to be disabling.