Age: 22.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Myocarditis, Pericarditis, Product dose omission issue
Clinical narrative: told her not to get the 2nd dose; chest pain in heart; shortness of breath; extreme fatigue; Myocarditis; staying in bed the whole time; inflammation; she wasn't feeling better; pericarditis; started feeling weak; This spontaneous case was reported by a consumer and describes the occurrence of ANGINA PECTORIS (chest pain in heart), DYSPNOEA (shortness of breath), ASTHENIA (started feeling weak), FATIGUE (extreme fatigue), PERICARDITIS (pericarditis) and MYOCARDITIS (Myocarditis) in a 22-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 (Patient had Covid 19 over the summer and her symptoms began on 1st week of July with a positive Covid test on July-2021) in July 2021. Previously administered products included for Fever: Advil and Tylenol.    On 07-Sep-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 08-Sep-2021, the patient experienced ANGINA PECTORIS (chest pain in heart) (seriousness criteria disability and medically significant), DYSPNOEA (shortness of breath) (seriousness criterion disability), FATIGUE (extreme fatigue) (seriousness criterion disability) and MYOCARDITIS (Myocarditis) (seriousness criteria disability and medically significant). In September 2021, the patient experienced ASTHENIA (started feeling weak) (seriousness criterion disability), PERICARDITIS (pericarditis) (seriousness criteria disability and medically significant), BEDRIDDEN (staying in bed the whole time), INFLAMMATION (inflammation) and MALAISE (she wasn't feeling better). The patient was treated with COLCHICINE for Inflammation, at a dose of .6 milligram twice a day. At the time of the report, ANGINA PECTORIS (chest pain in heart), DYSPNOEA (shortness of breath), ASTHENIA (started feeling weak), FATIGUE (extreme fatigue), PERICARDITIS (pericarditis), MYOCARDITIS (Myocarditis), BEDRIDDEN (staying in bed the whole time), INFLAMMATION (inflammation) and MALAISE (she wasn't feeling better) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Chest X-ray: abnormal (abnormal) myocarditis and pericarditis. On an unknown date, Echocardiogram: abnormal (abnormal) diagnosed with pericarditiss. On an unknown date, Electrocardiogram: abnormal (abnormal) diagnosed with myocarditis.  Also diagnosed pericarditis as well after looking at the same echocardiogram by 2nd cardiologist..     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication was reported.  It was reported that on 08-Sep-2021, 18 to 20 hours after the 1st dose, patient started having chest pain in her heart, shortness of breath, extreme fatigue. She went to urgent care on 08-Sep-2021, the doctor diagnosed her with myocarditis and prescribed steroids. About a week and half after the symptoms began, she wasn't feeling better even after staying in bed the whole time, started feeling weak and went to see the 1st cardiologist who diagnosed her with pericarditis after doing an echocardiogram and EKG. Three days later she went to a 2nd cardiologist to get a 2nd opinion. He diagnosed pericarditis as well after looking at the same echocardiogram and prescribed treatment to alleviate the inflammation. The 2nd cardiologist also did 2 blood tests to check for damage and blood clotting. The 2nd cardiologist also told her not to get the 2nd dose and that it would take about 6 months for the inflammation to go away.   Most recent FOLLOW-UP information incorporated above includes: On 30-Sep-2021: Follow up received and included no newinformation; Sender's Comments: This case concerns a 22 year-old female patient with reported history of covid-19, who experienced the unexpected serious events of dyspnoea and angina pectoris, and the expected but serious events of pericarditis and myocarditis. The event occurred 2 days after the first dose of mRNA-1273 vaccine for all the reported events, whit the exception of pericarditis, which occurred a week and a half after vaccination. The rechallenge was unknown for all the events, since they are not recovered/not resolved, and no information about second dose is provided. The medical history of Covid-19 infection remains as a confounder and a risk factor for the events of myocarditis and pericarditis. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.