Age: 84.0
Sex: M
Vaccine: COVID19
Symptoms: Inappropriate schedule of product administration, Muscular weakness, Neuropathy peripheral, Vaccination site dysaesthesia, Vaccination site movement impairment
Clinical narrative: 6 months interval between 1st and 2nd dose, and 5 months interval between 2nd and 3rd dose of Moderna vaccine; neuropathy in his arm/feet; Using his left arm to pick up his left arm; For several weeks the arm kept getting weaker; Nerves are rippling down from the spot he received the shot; This spontaneous case was reported by a consumer and describes the occurrence of NEUROPATHY PERIPHERAL (neuropathy in his arm/feet) in an 84-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 031H21A, 004M20A and 027620A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Prostate cancer, Lymphoma (lymphoma years ago), Chemotherapy (after chemo he had diabetes) and Surgery (surgery in his neck for his left arm (spinal stenosis surgery)). Concurrent medical conditions included Drug allergy (Allergic to Benadryl), Diabetic (after chemo he had diabetes) and Neuropathy (Neuropathy in his feet.).   On 06-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 21-Jul-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 08-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In February 2022, the patient experienced NEUROPATHY PERIPHERAL (neuropathy in his arm/feet) (seriousness criterion medically significant), VACCINATION SITE MOVEMENT IMPAIRMENT (Using his left arm to pick up his left arm), MUSCULAR WEAKNESS (For several weeks the arm kept getting weaker) and VACCINATION SITE DYSAESTHESIA (Nerves are rippling down from the spot he received the shot). On an unknown date, the patient experienced INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (6 months interval between 1st and 2nd dose, and 5 months interval between 2nd and 3rd dose of Moderna vaccine). At the time of the report, NEUROPATHY PERIPHERAL (neuropathy in his arm/feet), VACCINATION SITE MOVEMENT IMPAIRMENT (Using his left arm to pick up his left arm), MUSCULAR WEAKNESS (For several weeks the arm kept getting weaker) and VACCINATION SITE DYSAESTHESIA (Nerves are rippling down from the spot he received the shot) had not resolved and INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (6 months interval between 1st and 2nd dose, and 5 months interval between 2nd and 3rd dose of Moderna vaccine) outcome was unknown.            No concomitant medications were reported.  Patient received 3 doses of moderna COVID-19 vaccine and had some symptoms. After the third dose of vaccination in early part of February patient started to had symptoms. It was reported that by the end of February into the first part of March, patient had to use his left arm to pick up his left arm. Later the neurosurgeon confirmed that patient had neuropathy in his arm. It was reported that patient symptoms were worsened.  No treatment medications were reported.  Company Comment:  This is a spontaneous case concerning an 84-year-old male patient with relevant medical history of lymphoma, diabetes, neuropathy, post-procedural chemotherapy and spinal stenosis surgery, who experienced the unexpected serious (medically significant) event of Neuropathy peripheral (reported as neuropathy in his arm and feet), which occurred approximately 2 months after receiving the third dose of mRNA-1273 vaccine. Patient received 3 doses of mRNA-1273 vaccine with 6 months interval between 1st and 2nd dose, and 5 months interval between 2nd and 3rd dose (Inappropriate schedule of vaccine administered). No further details about the clinical course, diagnostic procedures and treatments were provided. At the time of report, the event was not yet resolved. The medical history of lymphoma, diabetes, neuropathy, post-procedural chemotherapy and spinal stenosis surgery remain as confounders for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-526951 (Patient Link).; Sender's Comments: This is a spontaneous case concerning an 84-year-old male patient with relevant medical history of lymphoma, diabetes, neuropathy, post-procedural chemotherapy and spinal stenosis surgery, who experienced the unexpected serious (medically significant) event of Neuropathy peripheral (reported as neuropathy in his arm and feet), which occurred approximately 2 months after receiving the third dose of mRNA-1273 vaccine. Patient received 3 doses of mRNA-1273 vaccine with 6 months interval between 1st and 2nd dose, and 5 months interval between 2nd and 3rd dose (Inappropriate schedule of vaccine administered). No further details about the clinical course, diagnostic procedures and treatments were provided. At the time of report, the event was not yet resolved. The medical history of lymphoma, diabetes, neuropathy, post-procedural chemotherapy and spinal stenosis surgery remain as confounders for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.