Age: 39.0
Sex: F
Vaccine: COVID19, COVID19, COVID19, COVID19, COVID19, COVID19
Symptoms: Antinuclear antibody, Antinuclear antibody positive, Autonomic nervous system imbalance, Blood pressure increased, Burning sensation
Clinical narrative: Neuropathy of the tongue, legs, hands etc; Lymphocytic colitis; My face started flushing and burning all the time; Tachycardia; Elevated blood pressure; Dizziness; After the second shot these episodes starred happening frequently along with diarrhea; My face started flushing and burning all the time; I was diagnosed with Dysautonomia/POTS; I was diagnosed with Dysautonomia/POTS; Small fiber neuropathy; now I have profound fatigue; Proximal muscle weakness; Testing positive for ANA and dsDNA; Testing positive for ANA and dsDNA; Became so ill; possible allergic reaction or mast cell activation syndrome; Ipossible allergic reaction or mast cell activation syndrome; This is a spontaneous report from a contactable physician reported for herself. A 39-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Left on an unspecified date (Batch/Lot Number: EL3302) as 2nd dose, single (at the age of 39-year-old) for COVID-19 immunisation. Medical history included Remote history of SVT (supraventricular tachycardia) from an unknown date and Tuberculin skin tests. Concomitant medications included vitamin B complex; vitamin D [vitamin D nos]; minerals nos, vitamins nos (PRENATAL VITAMINS), all taken for an unspecified indication within 2 weeks of vaccination.  The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. Prior to vaccination, the patient was not diagnosed with COVID-19. The patient was not pregnant at time of vaccination. The patient previously received the first dose of bnt162b2 (Lot number: EK9231) in Arm Left on 26Dec2020 at the age of 39-year-old for COVID-19 immunisation and experienced immediately flushed, tachycardia, elevated blood pressure, and dizziness. The patient reported immediately after each shot she got flushed, tachycardia, elevated blood pressure, and dizziness. After the second shot these episodes starred happening frequently along with diarrhea, neuropathy of the tongue, legs, hands etc. Her face started flushing and burning all the time. She became so ill she couldn't work for 6 weeks. The patient was diagnosed with Dysautonomia/POTS (Postural orthostatic tachycardia syndrome), lymphocytic colitis, and small fiber neuropathy. The patient took 17 days of steroids for possible allergic reaction or mast cell activation syndrome. She spoke with Dr who believed she had an autoimmune reaction to the vaccine causing inflammatory Dysautonomia and was enrolled in their trial. She had to take more time off work because now she had profound fatigue and proximal muscle weakness. The patient was testing positive for ANA (Antinuclear antibody) and dsDNA (Double stranded DNA antibody) but her rheumatologist did not think she had lupus. He and her neurologist felt that had have a vaccine induced autoimmune inflammatory disorder and that IVIG was the best treatment. Since the vaccination, the patient has been tested for COVID-19. The patient underwent lab tests and procedures which included ANA: positive on unknown date, dsDNA: positive on unknown date, PCR Nasal Swab: negative   on 26Mar2021, Tuberculin skin tests: unknown results on unknown date.  The patient received Prednisone as treatment for the adverse events. The adverse events result in Doctor or other healthcare professional office/clinic visit, Emergency room/department or urgent care and Disability or permanent damage. The outcome of events was not recovered.; Sender's Comments: The events were most likely intercurrent conditions and unlikely related to suspect product bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration, administered in Arm Left on an unspecified date (Batch/Lot Number: EL3302). This case will be reassessed upon receipt of follow-up information.