Sex: U
Vaccine: VARZOS
Symptoms: Sensitive skin
Clinical narrative: rash to my right chest / to my back as well / right side of trunk, front and back; intermittent burning pain to my trunk (on my chest); skin sensitivity.; intermittent burning pain to my trunk/pain is not severe or persistent enough; shivering, chills; low grade temp; This case was reported by a consumer and described the occurrence of shivering in a 60-year-old patient who received Herpes zoster (Shingrix) (batch number 2A3Z9, expiry date 14th October 2022) for prophylaxis.   On 12th January 2021, the patient received the 1st dose of Shingrix. On 12th January 2021, less than a day after receiving Shingrix, the patient experienced shivering and slight temperature. On 13th January 2021, the patient experienced chest burning pain of, sensitive skin and pain. On 18th January 2021, the patient experienced rash. The patient was treated with antivirals nos (Antiviral (Drug Name Unknown)) and gabapentin. On an unknown date, the outcome of the shivering and slight temperature were unknown and the outcome of the chest burning pain of, sensitive skin, pain and rash were not recovered/not resolved.   It was unknown if the reporter considered the shivering, slight temperature, chest burning pain of, sensitive skin, pain and rash to be related to Shingrix.  Additional details were provided as follows: The patient had reported the case for herself/himself and was close to 60 years old. The age at vaccination was not reported, howere it could be 59 or 60 years. The patient received Shingrix vaccine at the recommendation of his/her primary care provider for the first time on or about 12th January 2021 from a pharmacist. The reporter mentioned that, as per the PDF and according to the pharmacist, the Shingrix vaccine does not contain live virus and therefore could not trigger an infection nor would make him/her infectious to his/her 2 year old grandson whom he/she babysit 5 days a week. The patient experienced most of the side effects that the information PDF indicated primarily shivering, chills and low grade temperature with the exception of nausea. The patient experienced intermittent burning pain to his/her trunk (on chest) as well as skin sensitivity. The patient developed a rash to his/her right chest and on the day of reporting morning and developed a rash on back as well (rash was primarily on right side of trunk, front and back). The reporter mentioned that the pain was not severe or persistent enough for pain medication, however patient had to call his/her provider for antiviral medication (started on the day of reporting) and back up pain medication (gabapentin) to have on hand in the event the pain does become severe. The patient wanted to ask GSK infectious disease department if vaccine target the dormant varicella virus at the nerve root and if so, could the vaccine have irritated the nerve root somehow and this cause pain. If there was no live virus, what would have caused the eruption of the rash and could the vaccine have triggered an autoimmune response and was this what he/she experienced now. The reported batch number was 2A379, which does not exist in sales datasheet, hence updated as 2A3Z9 from sales datasheet. The consent to follow-up was requested.