Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Feeling drunk, Hormone level abnormal, Hyperaldosteronism, Investigation, Limb discomfort
Clinical narrative: Her hormone is wreaking havoc; heart failure; It was at 30% through an MRI stress test; Hyperaldosteronism; Also refers to it as Conns syndrome; Chills; Legs felt heavy on the second one/legs felt like lead; Arm hurt really bad; enlarged left ventricle; felt loopy like she had a couple drinks; refraction ejection rate is low; very sore from vomiting; the muscles are sore; very sore from vomiting; This is a spontaneous report from a contactable consumer (patient). A 60-years-old female patient received BNT162b2 (Pfizer BioNTech Covid-19 mRNA Vaccine, Solution for injection, Batch/Lot number: ER8732, Expiration date and NDC number was unknown) via an unspecified route of administration, administered in left arm on 05Apr2021 as dose 2, single (at the age of 59-years-old) for COVID-19 immunisation. Medical history included diagnosed with a latex allergy (not sure if it was the latex or the topper of the vaccine because it was rubber), back in 1991 or 1992, had vaccination for Hepatitis, had reaction in the thigh with itchiness, redness, and bumps, had cancer and right lower lobectomy (puts her at higher medical state in order to catch COVID). Patient was not on the heart medicine at the time of the first two COVID-19 Vaccines. Patient had no additional vaccines administered on same date of the Pfizer suspect. Patient had no prior vaccinations (within 4 weeks). Patient had no family medical history relevant to adverse event. The patient's concomitant medications were not reported. Historical vaccine included patient received BNT162b2 (Pfizer BioNTech Covid-19 mRNA Vaccine, Solution for injection, Batch/Lot number: EN6207, Expiration date and NDC number was unknown) via an unspecified route of administration, administered in left arm on 15Mar2021 as dose 1, single (at the age of 59-years-old) for COVID-19 immunisation and experienced chills and arm hurt. On an unspecified date of 2021, patient had very general, more like chills, patient felt loopy like she had a couple drinks, did not last long, legs felt heavy on the second one/legs felt like lead, very sore from vomiting, underneath, the muscles are sore. Patient talked to other people; they were feeling the same thing. On an unspecified date of 2021, patient had arm hurt really bad. On an unspecified date of 2021, patient found out she had an overproduction in her adrenal gland. On an unspecified date 2021, patient was diagnosed with hyperaldosteronism, also referred to it as Conns syndrome, patient stated had been going on for a while. On an unspecified date of 2021 (after first two shots), patient hormone was wreaking havoc. On Aug2021, patient had an enlarged left ventricle, thinks it was from the Conns Syndrome/ hyperaldosteronism. On an unspecified date of 2021, patient refraction ejection rate was low. They were trying to make it better and was considered heart failure. It was at 30% through an MRI stress test and was on medication now. Patient in the last month started a new medicine. Patient was on heart medicine from last visit. Patient does not know if that had anything to do with it. Patient was not having heart pain or palpitations, blood pressure was not increasing. On an unspecified date of 2021, patient shrunk, provides 5 feet 2.5 inches, because of the stupid hormone thing. Patient stated that did not find this out until Aug2021. Patient was on metoprolol extended release 24 hour (Ingenus Pharmac) at a dose of 25mg once daily with N25 imprinted on it and on Entresto (NDC: 0078-0529-20, Batch/Lot number: LK2134, Expiration date: Apr2024, Novartis), violet white oval tablet with NVR on front and LZ on back at a dose of 24mg-26mg tablet, 1 tablet by mouth twice a day. On Oct2021, ten days ago, patient started on spironolactone at a dose of 25 mg (Amnel Pharmce) round shaped tablet with AN511 imprinted on it for block production of the aldosterone hormone (small dose, one half a tablet every day). Patient had the two COVID-19 Vaccines, then started her heart medicine four weeks ago. Patient had no emergency Room and physician office visit for the events. Patient had bloodwork done because of this hormone, keeps checking with her heart medication and to make sure she was not dehydrated. Patient testing came back normal. The outcome of felt loopy like she had a couple drinks was recovered on an unspecified date of 2021 and unknown for rest of the events.  Follow-up attempts are completed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101495427 same patient/drug, different dose/event