Age: 66.0
Sex: F
Vaccine: COVID19
Symptoms: Hypoacusis, Inflammation, Inflammatory marker increased, Joint lock, Joint swelling
Clinical narrative: my legs felt paralyzed; Then my right knee swelled up so big it was like I had suffered an injury.; my knee was so bad I couldn't walk; severe inflammation in my shoulder/doctor told me there was nothing wrong with my knee, except extreme inflammation; my body was a target of swelling with no beginning and no pattern of where it would pop up next; shortness of breath; Then the worst symptoms were just a general filling of being unwell; different places in my bones I'd feel pain that would come and go in random places; The nerves in my teeth were "shocking" inside each tooth, especially my front teeth; sleeping was almost impossible due to the pain; I developed a large cyst on the upper part of my spine which continues to affect me.; it felt like an electric storm was in my body/ I experience a firestorm, electrical impulses, going out in my body. They are far less frequent and not nearly as intense, but they continue to happen when I get tired or stressed.; My hearing was affected on and off; My eyesight was affected on and off; my left side was hurting and locking/It would take me three or four hours to "unfreeze" my arms after sleeping at night/I could not even type; couldn't hold a teaspoon in my hand; arm on my left side was hurting and locking; my neck locked up and I couldn't turn my head/ arm on my left side was locking; my body was a target of pain / the pain that had been mostly on one side of my body moved to the other side; It was like hot spots. Like a fire had been started and it would radiate for a while and then it would just be gone; dizziness; muscle pain/muscles also felt like they were ripping; This spontaneous case was reported by a consumer and describes the occurrence of DIPLEGIA (my legs felt paralyzed), JOINT SWELLING (Then my right knee swelled up so big it was like I had suffered an injury.) and GAIT INABILITY (my knee was so bad I couldn't walk) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Ovarian cancer (treated with chemotherapy) in 2015 and Shoulder pain.    In March 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced DIPLEGIA (my legs felt paralyzed) (seriousness criterion medically significant), JOINT SWELLING (Then my right knee swelled up so big it was like I had suffered an injury.) (seriousness criterion medically significant), GAIT INABILITY (my knee was so bad I couldn't walk) (seriousness criterion medically significant), INFLAMMATION (severe inflammation in my shoulder/doctor told me there was nothing wrong with my knee, except extreme inflammation), SWELLING (my body was a target of swelling with no beginning and no pattern of where it would pop up next), DYSPNOEA (shortness of breath), MALAISE (Then the worst symptoms were just a general filling of being unwell), BONE PAIN (different places in my bones I'd feel pain that would come and go in random places), TOOTH DISORDER (The nerves in my teeth were "shocking" inside each tooth, especially my front teeth), SLEEP DISORDER (sleeping was almost impossible due to the pain), CYST (I developed a large cyst on the upper part of my spine which continues to affect me.), FEELING ABNORMAL (it felt like an electric storm was in my body/ I experience a firestorm, electrical impulses, going out in my body. They are far less frequent and not nearly as intense, but they continue to happen when I get tired or stressed.), AUDITORY DISORDER (My hearing was affected on and off), VISUAL IMPAIRMENT (My eyesight was affected on and off), MOBILITY DECREASED (my left side was hurting and locking/It would take me three or four hours to "unfreeze" my arms after sleeping at night/I could not even type), MOTOR DYSFUNCTION (couldn't hold a teaspoon in my hand), PAIN IN EXTREMITY (arm on my left side was hurting and locking), JOINT LOCK (my neck locked up and I couldn't turn my head/ arm on my left side was locking), PAIN (my body was a target of pain / the pain that had been mostly on one side of my body moved to the other side), FEELING HOT (It was like hot spots. Like a fire had been started and it would radiate for a while and then it would just be gone), DIZZINESS (dizziness) and MYALGIA (muscle pain/muscles also felt like they were ripping). The patient was treated with PREDNISONE for Inflammation, at an unspecified dose and frequency. At the time of the report, DIPLEGIA (my legs felt paralyzed), JOINT SWELLING (Then my right knee swelled up so big it was like I had suffered an injury.), GAIT INABILITY (my knee was so bad I couldn't walk), BONE PAIN (different places in my bones I'd feel pain that would come and go in random places), TOOTH DISORDER (The nerves in my teeth were "shocking" inside each tooth, especially my front teeth), SLEEP DISORDER (sleeping was almost impossible due to the pain), CYST (I developed a large cyst on the upper part of my spine which continues to affect me.), FEELING ABNORMAL (it felt like an electric storm was in my body/ I experience a firestorm, electrical impulses, going out in my body. They are far less frequent and not nearly as intense, but they continue to happen when I get tired or stressed.), AUDITORY DISORDER (My hearing was affected on and off), VISUAL IMPAIRMENT (My eyesight was affected on and off), MOBILITY DECREASED (my left side was hurting and locking/It would take me three or four hours to "unfreeze" my arms after sleeping at night/I could not even type), MOTOR DYSFUNCTION (couldn't hold a teaspoon in my hand), PAIN IN EXTREMITY (arm on my left side was hurting and locking), JOINT LOCK (my neck locked up and I couldn't turn my head/ arm on my left side was locking), PAIN (my body was a target of pain / the pain that had been mostly on one side of my body moved to the other side) and FEELING HOT (It was like hot spots. Like a fire had been started and it would radiate for a while and then it would just be gone) outcome was unknown and INFLAMMATION (severe inflammation in my shoulder/doctor told me there was nothing wrong with my knee, except extreme inflammation), SWELLING (my body was a target of swelling with no beginning and no pattern of where it would pop up next), DYSPNOEA (shortness of breath), MALAISE (Then the worst symptoms were just a general filling of being unwell), DIZZINESS (dizziness) and MYALGIA (muscle pain/muscles also felt like they were ripping) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood test: Inconclusive. On an unknown date, Inflammatory marker increased: Inconclusive.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Patient went to the ER three different times thinking she was dying and was raised being conservative with respect to vaccinations, so  didn'tto vaccinations, so didn't even want to tell her family that she had received the shot. Doctor scheduled for surgery and took her into surgery and within 20 minutes I was out of surgery and back in recovery. When she woke up, the doctor told her there was nothing wrong with her knee, except extreme inflammation, and he had not seen anything like that ever.  Patient adverse reaction has been going on now for over two years. In several ER visits they looked for blood clots in lungs and heart. One ER visit was especially interesting early on as a rheumatologist happened to be in the ER and so he had them check for inflammation and he said my markers were high. Patient had went through chemo for ovarian cancer and lived through that horrific experience, but this experience was far far worse.  It is unknown if the patient experienced any additional symptoms/events.   This case was linked to US-MODERNATX, INC.-MOD-2023-727508, US-MODERNATX, INC.-MOD-2023-727515 (E2B Linked Report).  Company Comment: This is a spontaneous case regarding a 66-year-old female patient with medical history of ovarian cancer and shoulder pain, who experienced unexpected and medically significant events of diplegia, knee swelling and gait inability - among other non serious events - after receiving first dose of mRNA-1273 vaccine. Patient stated that she was vaccinated in late March, and the symptoms began just a few days after. It began with severe inflammation in her shoulder and within two or three days the arm on the left side was hurting and locking, almost freezing in place. Within about 10 days her neck locked up and she couldn't turn her head. Then her right knee swelled up, and additionally she experienced bone pain, nerves in her teeth were "shocking" inside each tooth, general body pain, a large cyst on the upper part of the spine, electrical impulses going out in her body (like an electric storm), and some days her legs felt paralyzed. Patient went to the ER three different times thinking she was dying. After two months she went to see an orthopedic surgeon as her knee was so bad she couldn't walk; doctor said she had a torn meniscus and performed surgery after which doctor told her there was nothing wrong with her knee, except extreme inflammation, and he had not seen anything like that ever. Patient developed dizziness and shortness of breath that comes and goes; in several ER visits doctors looked for blood clots in lungs and heart. Rheumatologist said that inflammation markers were high. After about 11 months the severity of the bone and muscle pain and the paralysis that would come and go, began to ease up. Then the worst symptoms were just a general filling of being unwell, unstable, dizzy, with major flareups about every 2 to 3 weeks. Patient was treated with prednisone, and that was the only thing that would unlock her neck or allow her to use the keyboard, because she could not even type. She stated that symptoms were less frequent and not nearly as intense, but they continue to happen when she get tired or stressed. Patient didn't have a diagnosis but regarding the sore shoulder, her doctor said that sometimes when you get a shot, a virus will intensify a situation that already exists. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. Medical history of ovarian cancer and shoulder pain remain confounding factors. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case regarding a 66-year-old female patient with medical history of ovarian cancer and shoulder pain, who experienced unexpected and medically significant events of diplegia, knee swelling and gait inability - among other non serious events - after receiving first dose of mRNA-1273 vaccine. Patient stated that she was vaccinated in late March, and the symptoms began just a few days after. It began with severe inflammation in her shoulder and within two or three days the arm on the left side was hurting and locking, almost freezing in place. Within about 10 days her neck locked up and she couldn't turn her head. Then her right knee swelled up, and additionally she experienced bone pain, nerves in her teeth were "shocking" inside each tooth, general body pain, a large cyst on the upper part of the spine, electrical impulses going out in her body (like an electric storm), and some days her legs felt paralyzed. Patient went to the ER three different times thinking she was dying. After two months she went to see an orthopedic surgeon as her knee was so bad she couldn't walk; doctor said she had a torn meniscus and performed surgery after which doctor told her there was nothing wrong with her knee, except extreme inflammation, and he had not seen anything like that ever. Patient developed dizziness and shortness of breath that comes and goes; in several ER visits doctors looked for blood clots in lungs and heart. Rheumatologist said that inflammation markers were high. After about 11 months the severity of the bone and muscle pain and the paralysis that would come and go, began to ease up. Then the worst symptoms were just a general filling of being unwell, unstable, dizzy, with major flareups about every 2 to 3 weeks. Patient was treated with prednisone, and that was the only thing that would unlock her neck or allow her to use the keyboard, because she could not even type. She stated that symptoms were less frequent and not nearly as intense, but they continue to happen when she get tired or stressed. Patient didn't have a diagnosis but regarding the sore shoulder, her doctor said that sometimes when you get a shot, a virus will intensify a situation that already exists. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. Medical history of ovarian cancer and shoulder pain remain confounding factors. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report. US-MODERNATX, INC.-MOD-2023-727508:Reporter Son's Case US-MODERNATX, INC.-MOD-2023-727515:Cluster case for people