Age: 89.0
Sex: F
Vaccine: COVID19
Symptoms: Accidental overdose, Asthenia, Fatigue, Feeding disorder, Headache
Clinical narrative: Limbs continue to feel like they are made of wet spaghetti; Heart rate started to bounce up and down; Couldn't eat anything; Muscle pains, everything on her body started to ache; Extreme fatigue, exhaustion; Headache; Wife was given a larger dose of the Moderna covid19 booster/a full dose instead of a half a dose; She is very weak; Slipped and broke her shoulder; This spontaneous case was reported by a consumer and describes the occurrence of ACCIDENTAL OVERDOSE (Wife was given a larger dose of the Moderna covid19 booster/a full dose instead of a half a dose), ASTHENIA (She is very weak), MUSCULAR WEAKNESS (Limbs continue to feel like they are made of wet spaghetti), UPPER LIMB FRACTURE (Slipped and broke her shoulder) and HEART RATE IRREGULAR (Heart rate started to bounce up and down) in an 89-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 012F21A, 011A21A and 030L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Shoulder operation (She slipped and broke her shoulder and arm on 18 APR 2021. She had a reverse shoulder operation and has been in physical therapy for the past 5-6 months.).   On 07-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 07-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 23-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. On 18-Apr-2021, the patient experienced UPPER LIMB FRACTURE (Slipped and broke her shoulder). In October 2021, the patient experienced ASTHENIA (She is very weak). On 23-Oct-2021, the patient experienced ACCIDENTAL OVERDOSE (Wife was given a larger dose of the Moderna covid19 booster/a full dose instead of a half a dose). On 24-Oct-2021, the patient experienced MUSCULAR WEAKNESS (Limbs continue to feel like they are made of wet spaghetti), HEART RATE IRREGULAR (Heart rate started to bounce up and down), FEEDING DISORDER (Couldn't eat anything), MYALGIA (Muscle pains, everything on her body started to ache), FATIGUE (Extreme fatigue, exhaustion) and HEADACHE (Headache). The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) ongoing since an unknown date for Adverse event, at a dose of 500 mg twice a day; GLUCOSE, POTASSIUM CHLORIDE, SODIUM CHLORIDE, SODIUM CITRATE (ORAL REHYDRATION SALTS III) ongoing since an unknown date for Dehydration, at an unspecified dose and frequency and Physical therapy for Upper limb fracture. On 23-Oct-2021, ACCIDENTAL OVERDOSE (Wife was given a larger dose of the Moderna covid19 booster/a full dose instead of a half a dose) had resolved. On 26-Oct-2021, HEADACHE (Headache) had resolved. At the time of the report, ASTHENIA (She is very weak), UPPER LIMB FRACTURE (Slipped and broke her shoulder), HEART RATE IRREGULAR (Heart rate started to bounce up and down), FEEDING DISORDER (Couldn't eat anything) and MYALGIA (Muscle pains, everything on her body started to ache) outcome was unknown and MUSCULAR WEAKNESS (Limbs continue to feel like they are made of wet spaghetti) and FATIGUE (Extreme fatigue, exhaustion) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Heart rate: 52-98 (normal) 52-98.most part it hung around the 80s and 90s but it would bounce up and down..         No concomitant medications were reported. Patient ad a treatment  for Reverse shoulder operation and Physical therapy.  Patient did not had fever and her O2 levels were fine.   Most recent FOLLOW-UP information incorporated above includes: On 30-Oct-2021: Significant follow up appended (Event updated) On 01-Nov-2021: Significant follow up appended: Product details, Patient details and Events updated On 03-Nov-2021: Non significant followup On 03-Nov-2021: FU received - non significant On 04-Nov-2021: Non signi follow-up received contains No New Information; Sender's Comments: This spontaenous case of accidental overdose concerns an 89-year-old female patient with no relevant medical history reported, who experienced non-serious unexpected event of special interest (AESI) muscular weakness and heart rate irregular. The events occurred 1 day ater the third dose of the Moderna COVID-19 Vaccine (mRNA-1273). Rechallenge was not applicable since the event occurred after the third dose so, no rechallenge was done and recurrence was not applicable.  The benefit-risk relationship of drug is not affected by this report.