Age: 54.0
Sex: F
Vaccine: COVID19
Symptoms: Multiple sclerosis relapse
Clinical narrative: Bad multiple sclerosis relapse; This spontaneous case was reported by a patient and describes the occurrence of MULTIPLE SCLEROSIS RELAPSE (Bad multiple sclerosis relapse) in a 54-year-old female patient who received mRNA-1273 (Spikevax) for COVID-19 prophylaxis.     Concurrent medical conditions included Multiple sclerosis.    In 2022, the patient received first dose of mRNA-1273 (Spikevax) (unknown route) 1 dosage form. On an unknown date, the patient experienced MULTIPLE SCLEROSIS RELAPSE (Bad multiple sclerosis relapse) (seriousness criterion medically significant). At the time of the report, MULTIPLE SCLEROSIS RELAPSE (Bad multiple sclerosis relapse) had resolved.        The action taken with mRNA-1273 (Spikevax) (Unknown) was unknown.       No concomitant medication reported.  It was reported that patient received first moderna shot about 2 months before reporting. The patient could not walk for 3 days, really bad vertigo, could not walk, additionally mentioned her legs would not support her, vertigo was horrid, the patient believed the Moderna put her in a bad multiple sclerosis relapse, lasted for 3-4 days and then resolved. GAIT INABILITY (Patient could not walk for 3 days/ my legs wouldn't support me) and VERTIGO (Had really bad vertigo/ Vertigo was horrid) were the possible symptoms of multiple sclerosis relapse.  No treatment medication reported.  Company comment This is a spontaneous case concerning a 54-year-old female patient with medical history of Multiple sclerosis, who experienced the serious, Medically Significant, unexpected AESI event of Multiple sclerosis relapse and received the first dose of mRNA-1273 and had recovered at the time of the last observation. Exact vaccination date and event onset date are unknown, thus, exact latency between vaccination and onset of the event could not be assessed. It was reported that he received the first dose, and the patient could not walk for three days, had a really bad vertigo and could not walk. This lasted three to four days and then resolved. The mentioned medical history could be a confounder for the event. No further clinical information was provided for review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning a 54-year-old female patient with medical history of Multiple sclerosis, who experienced the serious, Medically Significant, unexpected AESI event of Multiple sclerosis relapse and received the first dose of mRNA-1273 and had recovered at the time of the last observation. Exact vaccination date and event onset date are unknown, thus, exact latency between vaccination and onset of the event could not be assessed. It was reported that he received the first dose, and the patient could not walk for three days, had a really bad vertigo and could not walk. This lasted three to four days and then resolved. The mentioned medical history could be a confounder for the event. No further clinical information was provided for review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.