Age: 38.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Leukocytosis, Malaise, Myocarditis, Pyrexia, SARS-CoV-2 test
Clinical narrative: myocarditis; abdominal discomfort; fever; chills; malaise; fatigue; chest pain; This spontaneous case was reported by a physician (subsequently medically confirmed) and describes the occurrence of MYOCARDITIS (myocarditis), ABDOMINAL DISCOMFORT (abdominal discomfort), PYREXIA (fever), CHILLS (chills), MALAISE (malaise), FATIGUE (fatigue) and CHEST PAIN (chest pain) in a 38-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Glioblastoma multiforme (in remission) in 2018 and CVA in 2018. Concomitant products included TEMOZOLOMIDE (TEMODAR) for an unknown indication.    On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced MYOCARDITIS (myocarditis) (seriousness criterion hospitalization), ABDOMINAL DISCOMFORT (abdominal discomfort) (seriousness criterion hospitalization), PYREXIA (fever) (seriousness criterion hospitalization), CHILLS (chills) (seriousness criterion hospitalization), MALAISE (malaise) (seriousness criterion hospitalization), FATIGUE (fatigue) (seriousness criterion hospitalization) and CHEST PAIN (chest pain) (seriousness criterion hospitalization). At the time of the report, MYOCARDITIS (myocarditis), ABDOMINAL DISCOMFORT (abdominal discomfort), PYREXIA (fever), CHILLS (chills), MALAISE (malaise), FATIGUE (fatigue) and CHEST PAIN (chest pain) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Acute kidney injury: unknown (Inconclusive) unknown. In 2021, Angiogram: abnormal (abnormal) Bilateral lower lobe patchy and ground glass airspace opacities and mild degree of ground glass opacity within the peripheral right middle lobe.. In 2021, Echocardiogram: abnormal (abnormal) severe Hypokinesis of the mid to distal segments and apex, hypercontractile base--> estimated EF = 30% (Last known baseline 3/2019 EF 65%).. In 2021, Electrocardiogram: abnormal (abnormal) abnormal. In 2021, Fibrin D dimer: increased (High) increased. In 2021, Hyponatraemia: abnormal (abnormal) abnormal. In 2021, Leukocytosis: abnormal (abnormal) abnormal. In 2021, SARS-CoV-2 test: negative (Negative) negative. In 2021, Transaminases increased: abnormal (abnormal) abnormal. In 2021, Troponin: abnormal (abnormal) elevated troponin of 12.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment was unknown.  Continued to be hypotensive despite fluid and initiated on Levophed. Taken to cath lab with no evidence of coronary disease, LVEF down to 10% on LV gram, right heart catherization with evidence of elevated pulmonary capillary wedge pressure, patient was placed on Impella CP support.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However, Further information has been requested.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However, Further information has been requested.