Age: 42.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Rhinorrhoea, Sick leave, Sinus disorder, Sinus operation, Sneezing
Clinical narrative: The Covid-19 Moderna vaccines that received caused my body to develop EGPA or Eosinophilic granulomatosis with polyangiitis to develop.   I received my first vaccine on 2/26/21 in my left arm and developed "Moderna arm" or a large chemical burn under my skin.  I ignored this system, as I read this was "normal".  I received by second vaccine on 3/26/21 in my right arm and again developed "Moderna arm" and flu like symptoms.   Three months after my second injection I developed severe asthma-like symptoms and rhinitis (the first stage  symptoms of EGPA).   My primary care physician, Dr., diagnosed it as asthma and rhinitis and prescribed allergy medication.  I was uncontrollably sneezing, wheezing, coughing,    and dealing with a runny nose.   The medication that Dr. initially prescribed me did not work in 8/21, so I returned to her and she prescribed Prednisone in 9/21 ( a medication known to put EGPA into remission).  This seemed to do the trick and it seemed like the symptoms were put into remission.  At the time, I did not know it was EGPA, I thought it was just asthma and rhinitis.   Therefore, not knowing the link between the Covid-19 Moderna vaccine and my symptoms, I then got the Covid-19 booster on 11/7/21 in my left arm.  I again got the "Moderna arm" and flu like symptoms.    Then on 2/26/22, I contracted Covid-19.  The virus was mild and I recovered in less than 10 days.   Roughly 3 months after contracting Covid-19 and 6 months after I received the Covid-19 booster, the EPGA returned and was uncontrollable.  Dr., my primary care physician, again prescribed Prednisone, but it did not have the same effect as the year prior.  She referred me to Dr., Allergist, and Dr., Pulmonologist in 8/22.   At this time, I started getting odd rashes on my body, like skin gradulomas (a symptom of EPGA). Dr. had me on Prednisone of the entire month of December 2022 because my asthma and rash symptoms were out of control.   I also went into the ER in December of 2022 with chest pain and a growing pericardial cyst was discovered on my heart.   Dr. did allergy testing and found no red-herring that explained my symptoms.  Dr. did a blood test and discovered that my eosinophil count was abnormally high (the second stage of EGPA) and he ordered a CT of my sinuses, only to discover that my sinuses were fully impacted (a sign confirming EGPA), my lungs were also being impacted.     In February of 2023, I was really sick because the esinophils had attacked my lungs.  My lung function was down and my oxygen saturation was 88% and was coughing up mucus plugs on the daily.   Dr. officially diagnosed me with EGPA in March of 2023.  He referred me to Dr. to have sinus surgery to assist in clearing out my sinuses.  He also worked with Dr. to put me on Xolair to help control my esinophil count.    At the end of July 2023, I went into the ER yet again with chest pain and they discovered that the pericardial cyst on my heart had doubled in size. They referred me to Dr., a cardiologist, to monitor my heart.  He referred me to Dr. to have the cyst removed and examined.   In August of 2023, Dr. performed sinus surgery to removed the debris in my impacted sinuses.    Because I had been on Prednisone of 8 months, I had major issues with Prednisone withdrawal.  I was in adrenal fatigue and became insulin dependent.  I was in the ER several times for health issues surrounding the Prednisone overuse and  withdrawal, including non-alcoholic fatty liver disease and a peptic ulcer.  I was put on medical leave from my career as a teacher.  In October of 2023, I had surgery to removed the perecardial cyst on my heart.  The cyst was benign.   Dr. then swiched my biologic from Xolair to Nucala in hopes that it would put the EPGA into remission.  We are still waiting to see if it will be successful.