Age: 44.0
Sex: F
Vaccine: HPV4
Symptoms: Pain in extremity, Paraesthesia, Polyneuropathy, Reflex test, Relapsing-remitting multiple sclerosis
Clinical narrative: polyneuropathy/autonomic inj/neuropathy on the the right half of her body from her chest to her toes/tingling on her right side/tingling sensation in her right foot/sweating profusely/left arm pain/cold sensitivity on the right lower half of her body; subject also got hot and cold; After receiving the second Gardasil vaccine, subject fainted almost immediately; RRMS/autoimmune/neurological/autonomic injuries and resulting sequalae/cold sensitivity/brain fog/fatigue; extreme mood swings; Information has been received from a lawyer, regarding a case in litigation and concerning a female patient (pt) of an unknown age. No information concerning the pt's medical history, concurrent conditions or concomitant medications was provided.  The pt's health care provider recommended the pt to receive the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, which was touted as a safe and effective vaccine for preventing cervical cancer. In light of the pt's doctor's recommendations, she consented to being injected with quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL). Before the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, the pt had no health issues. She lived a healthy life, embracing opportunities including traveling, running, working out, leadership roles in and out of school, and handling daily chores and work. On 08-APR-2021, when the patient was 44 years old, she received his first dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported) for preventing cervical cancer. On 17-MAY-2021, the pt received his second dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported) for preventing cervical cancer. After receiving the second vaccine, the pt fainted almost immediately. She also got hot and cold and sweated profusely. On an unspecified date in 2021, within four weeks of receiving the second vaccine, the pt began to experience cold sensitivity, tingling on her right side, left arm pain, brain fog, extreme mood swings, fatigue, and general discomfort on the right side of her body including neuropathy on the right half of her body from her chest to her toes. On an unspecified date in May 2021, the pt was diagnosed with polyneuropathy and was referred to a neurologist. She underwent more than a dozen blood tests, half-a-dozen reflex tests and appointments, an EMG, MRIs with and without contrast for brain, cervical spine, thoracic spine, and lumbar spine. She received a lumbar puncture. She had an exam and other ophthalmological tests completed to look for signs of optic neuritis by an ophthalmologist. The pt received a three-day Solu-Medrol infusion in the summer of 2021. It was initially determined by one doctor and confirmed by a second opinion from another doctor that the pt had multiple sclerosis. On 08-JUL-2021, she was officially diagnosed with relapsing-remitting multiple sclerosis (RRMS) by the first doctor. As of February 2024, the pt was taking vumerity, multiple vitamins and supplements, and metformin. She experiences daily neuropathy and cold sensitivity on the right lower half of her body, and tingling sensation in her right foot. She experienced pronounced fatigue on a near daily basis. Her brain fog has become more pronounced over the past three years has impacted her teaching career and her ability to continue in some leadership positions outside of school. The reporter noted serious and debilitating injuries, including but not limited to autonomic, autoimmune, and neurological injuries and resulting sequalae (also reported as serious autoimmune and neurological injuries/ dysfunctions) that the pt sustained as a result of receiving the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine. The pt's injuries from the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccinations were ongoing, and she would suffer from RRMS for the rest of her life. She would require routine blood work, MRIs, and multiple doctor appointments each year. The pt contended that her quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune and neurological injuries, including but not limited to RRMS, brain fog, neuropathy, and fatigue as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which are alleged herein and all of which were caused by quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) induced autoimmune and neurological disorder. The pt had suffered and at the time of report continued to suffer severe and permanent physical injuries and associated symptomatology and had suffered severe and permanent emotional injuries, including pain and suffering. She also has a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her autoimmune disease, neurological disease and other injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the has suffered at the time of report continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of the events of RRMS, polyneuropathy, syncope, feeling of body temperature change and mood swings was considered to be not recovered.  The lawyer considered the events of RRMS, polyneuropathy, syncope, feeling of body temperature change and mood swings to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL).  Upon internal review, the events of RRMS, polyneuropathy and syncope was determined to be medically significant.  The events of RRMS, polyneuropathy, syncope, feeling of body temperature change and mood swings were considered to be disabling.