Age: 47.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Skin discolouration
Clinical narrative: She was still experiencing sharp pain; Lost taste buds; Felt Weird; Dog scratched in the right arm and showed up on left arm; left toe was broken; Dark red mark (no uplifted) on left  arm; Extremely tired; Pain in right toe/left toe was broken and had pain in her right toe; Wrist pain/ Patient  had wrist pain from old injury on one  of her hands and now she felt it in the Other wrist; REVACCINATION DIFFERENT COVID-19 VACCINE; Interchange of vaccine products; This spontaneous case was reported by a consumer and describes the occurrence of PAIN (She was still experiencing sharp pain), AGEUSIA (Lost taste buds), FEELING ABNORMAL (Felt Weird), ANIMAL SCRATCH (Dog scratched in the right arm and showed up on left arm) and FOOT FRACTURE (left toe was broken) in a 47-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) for COVID-19 prophylaxis.    Patient never had allergic reaction before in her life.  The patient's past medical history included Injury, Pain (Old injuries) and Wrist pain (Old injuries). Previously administered products included for COVID-19 prophylaxis: JANSSEN COVID-19 VACCINE (Dose 1, Reaction start date:26-Aug-2021) on 01-Apr-2021, JANSSEN COVID-19 VACCINE (Dose 1, Reaction start date:26-Aug-2021) on 01-Apr-2021, JANSSEN COVID-19 VACCINE (Dose 1, Reaction start date:26-Aug-2021) on 01-Apr-2021, JANSSEN COVID-19 VACCINE (Dose 1, Reaction start date was post dose 1) on 01-Apr-2021, JANSSEN COVID-19 VACCINE (Dose 1, Reaction start date:26-Aug-2021) on 01-Apr-2021, JANSSEN COVID-19 VACCINE (Dose 1 and Reaction start date:26-Aug-2021) on 01-Apr-2021; for Drug use for unknown indication: benadryl in August 2021. Past adverse reactions to the above products included Bee sting with JANSSEN COVID-19 VACCINE; Diarrhea with JANSSEN COVID-19 VACCINE; Extremities burning sensation of with JANSSEN COVID-19 VACCINE; No adverse event with benadryl; Sensation of pressure with JANSSEN COVID-19 VACCINE; Sleep disorder with JANSSEN COVID-19 VACCINE; and Swelling of hands with JANSSEN COVID-19 VACCINE. Concurrent medical conditions included Brace user (wrist brace), Seafood allergy, Abstains from alcohol and Cigarette smoker (smoke once in a blue moon).   On 25-Oct-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient received third dose of TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) (unknown route) 1 dosage form. On 25-Oct-2021, the patient experienced COVID-19 IMMUNISATION (REVACCINATION DIFFERENT COVID-19 VACCINE) and INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine products). On an unknown date, the patient experienced PAIN (She was still experiencing sharp pain), AGEUSIA (Lost taste buds), FEELING ABNORMAL (Felt Weird), ANIMAL SCRATCH (Dog scratched in the right arm and showed up on left arm), FOOT FRACTURE (left toe was broken), SKIN DISCOLOURATION (Dark red mark (no uplifted) on left  arm), FATIGUE (Extremely tired), PAIN IN EXTREMITY (Pain in right toe/left toe was broken and had pain in her right toe) and ARTHRALGIA (Wrist pain/ Patient  had wrist pain from old injury on one  of her hands and now she felt it in the Other wrist). At the time of the report, PAIN (She was still experiencing sharp pain) had not resolved and AGEUSIA (Lost taste buds), FEELING ABNORMAL (Felt Weird), ANIMAL SCRATCH (Dog scratched in the right arm and showed up on left arm), FOOT FRACTURE (left toe was broken), SKIN DISCOLOURATION (Dark red mark (no uplifted) on left  arm), FATIGUE (Extremely tired), PAIN IN EXTREMITY (Pain in right toe/left toe was broken and had pain in her right toe), ARTHRALGIA (Wrist pain/ Patient  had wrist pain from old injury on one  of her hands and now she felt it in the Other wrist), COVID-19 IMMUNISATION (REVACCINATION DIFFERENT COVID-19 VACCINE) and INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine products) outcome was unknown.            Concomitant product use was not provided by the reporter. Patient stated that having mirror images of old injuries coming back on the opposite side of her body (dose number in Series 2) and injuries showing on other side of the body as mirror image for injuries that patient had in the past. The patient consulted with physician, but it was told that they cannot do anything about it. It was reported that patient lost taste buds was which was weird, and it felt by patient after 2nd vaccination. The reporter causality for the events of pain, ageusia, fatigue, feeling abnormal, contusion, skin discoloration, pain in extremity, arthralgia and foot fracture with respect to Janssen Covid-19 vaccine was reported as possible. Treatment information was not provided. Company comment This spontaneous case concerns a 47-year-old female patient, with no relevant medical history reported, who experienced the unexpected, non-serious, AESI of ageusia and received the second dose of mRNA-1273. The event onset date was not provided, thus, exact latency between vaccination and onset of the event could not be assessed. The patient had received previously Janssen COVID-19 vaccine and on an unknown date, Pfizer COVID-19 vaccine. Interchange of vaccine products and Revaccination Different COVID-19 Vaccine were considered as additional events. It was reported that after the second dose, the patient was experiencing sharp pain, lost taste buds. The patient consulted with physician but was told that they cannot do anything about it. The non-serious events of foot fracture, animal scratch (in the context of a dog's scratch), pain in extremity (in the context of left toe broken) and arthralgia (in the context of an old injury) were assessed as not related to the vaccine due to the lack of biological plausibility. No further clinical information was provided for review. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.