Sex: M
Vaccine: COVID19
Symptoms: Arthralgia, Arthritis, Discomfort, Gait disturbance, Insomnia
Clinical narrative: discomfort in his hips and legs/pain in hips and legs was increasing; x-ray of hips and found I had a lot of arthritis; couldn't sleep in his bed anymore; discomfort spread to shoulders, hands, mid back and neck; can't raise my arms above my shoulder. I can put a cup in the kitchen cabinet not at least a little bit of movement; I can't walk, or go out; can't raise my arms above my shoulder. I can put a cup in the kitchen cabinet not at least a little bit of movement; This is a spontaneous report received from a contactable reporter(s) (Physician) from medical information team. The reporter is the patient.  A 90-year-old male patient received BNT162b2 (BNT162B2), on 13May2022 as dose 4 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "Diabetic" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (1st dose), for COVID-19 immunization; Bnt162b2 (2d dose), for COVID-19 immunization; Covid-19 vaccine (1st booster dose, Manufacturer unknown), for COVID-19 immunization. The following information was reported: GAIT DISTURBANCE (non-serious) with onset May2022, outcome "unknown", described as "I can't walk, or go out"; MOVEMENT DISORDER (non-serious), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious) all with onset May2022, outcome "unknown" and all described as "can't raise my arms above my shoulder. I can put a cup in the kitchen cabinet not at least a little bit of movement"; INSOMNIA (non-serious) with onset May2022, outcome "unknown", described as "couldn't sleep in his bed anymore"; ARTHRALGIA (medically significant) with onset May2022, outcome "unknown", described as "discomfort in his hips and legs/pain in hips and legs was increasing"; DISCOMFORT (non-serious) with onset May2022, outcome "unknown", described as "discomfort spread to shoulders, hands, mid back and neck"; ARTHRITIS (medically significant) with onset May2022, outcome "unknown", described as "x-ray of hips and found I had a lot of arthritis". The events "discomfort in his hips and legs/pain in hips and legs was increasing", "x-ray of hips and found i had a lot of arthritis", "couldn't sleep in his bed anymore", "discomfort spread to shoulders, hands, mid back and neck", "can't raise my arms above my shoulder. i can put a cup in the kitchen cabinet not at least a little bit of movement" and "i can't walk, or go out" required physician office visit. The patient underwent the following laboratory tests and procedures: Weight decreased: lost 20 pounds, notes: he has lost 20 pounds in the last 12 months; X-ray of pelvis and hip: lot of arthritis, notes: x-ray of hips and found I had a lot of arthritis. Therapeutic measures were taken as a result of arthralgia, arthritis, insomnia, discomfort.  Clinical information: The patient had the first two doses of Pfizer covid vaccine , got first shot booster and on 13May, got his second booster. 10 days later started to experience discomfort in his hips and legs couldn't sleep in his bed anymore, discomfort spread to shoulders, hands, mid back and neck. Only thing he can relate it to is the Covid vaccine. Patient was Diabetic and could not wind up on steroids to reduce inflammation, not in abundance. Patient stated that it's the only thing new in life and never had anything like this, it's like a generalized flare, its everything in my body, spine, hips, and hands are starting getting this. The first week, started utilizing Motrin and Aleve like it was going out of style, plus sleeping in recliner chair couldn't get in bed, pain in hips and legs was increasing, so finally patient's wife, had some narcotics, oxycodone, due to her previous compression fracture in spine and back pain, so rheumatologist prescribed them and patient's wife gave a half of one, and it didn't do a damn thing, excurse language. Had to wait until Monday to get an appointment with a pain doctor, when went for the appointment, the doctor was on vacation and could only be seen by PA. Patient had seen another pain doctor and got an appointment, did an x-ray of hips and found had a lot of arthritis, for which was scheduled for injection that was for two weeks later. Patient was 2 weeks with no pain killers, no relief. The only thing had was Motrin and Aleve and in the meantime shoulders started giving problems and never had this before. Patient wound up getting a shot in the hip, but it diminished the pain for a few days and now here. The patient could not walk, or go out, can't raise arms above shoulder. Can put a cup in the kitchen cabinet not at least a little bit of movement. It was okay If sit like a mummy all day long, if I don't move, but a little movement...(inaudible). Patient stated that had lost 20 pounds in the last 12 months. He could not eat. The patient fortunately had another appointment to see a doctor, may only be able to offer a cortisone shot and there goes diabetes. He was doing fine up until the last shot. Up until May 13th until roughly the end of the month, wasn't doing bad, He didn't have immediate side effects, it seemed to be occurring a little by little after that, going and hitting all the joints and pain flare ups. Had never thought of the relation to the covid 19 vaccine before, until just recently. Patient stated that while practicing many years ago there was a dry cough with a new medicine, and he was inquiring with two cardiologists that never heard of it, it turned out it was a breakdown in the product of that blood pressure medication as it circulated through the lungs it became an irritant and it was pulled off the market. But the investigation came from the manufacturer. He used to be active, did all landscaping and lawn work until a year ago when wife thought that he was getting too old for that kind of work, then she started hiring someone else for that. In the past couple of months had been in such discomfort, had never experienced this in the life. It had been the worse several months of his life.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: As there is limited information in the case provided, the causal association between the event Arthralgia, arthritis  and the suspect drug cannot be excluded. The case will be reassessed once new information is available.  The impact of this report on the benefit/risk profile of the Pfizer drug is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees, and Investigators, as appropriate.