Age: 37.0
Sex: F
Vaccine: RAB, RAB, RAB, UNK
Symptoms: Inappropriate schedule of product administration, Insomnia, Malaise, Myoclonus, Tinnitus
Clinical narrative: 1st dose on day 0 and the 2nd dose on day 7 since they missed day 3. since getting the 2nd dose; experienced hallucinations; very sick; chest pains, firework feeling in their chest- like a heart attack; chest pains, firework feeling in their chest- like a heart attack; jump at sleep /could not sleep/insomnia; lost 20 pounds; tremors in hands; anxiety; really bad ringing in my ears that persisted has been since the injection/tinnitus; could not eat; Initial information received on 08-Jul-2025 regarding an unsolicited valid serious case received from a consumer/non-hcp (health care professional).  This case involves a 37 years old female patient who received 1st dose of Rabies vaccine inact (chick embryo) (Rabavert) on day 0 and 2nd dose of rabies (HDC) vaccine [Imovax rabies] on day 7 since they missed day 3 and had very sick, hallucinations, chest pains, firework feeling in their chest- like a heart attack, chest pains, jump at sleep/could not sleep/insomnia, lost 20 pounds, tremors in hands, anxiety, really bad ringing in my ears that persisted has been since the injection/tinnitus and could not eat.  The patient's past medical history included Illness anxiety disorder. The patient's past medical treatment(s), vaccination(s) and family history were not provided.  On an unknown date in March 2025, the patient received an unknown dose (dose 1) of suspect Rabies vaccine inact (chick embryo) on day 0 (unknown formulation) not produced by Sanofi Pasteur for prophylactic vaccination (Immunisation) and received an unknown dose (dose 2) of suspect rabies (HDC) vaccine (formulation: Powder and solvent for suspension for injection) for rabies (Rabies immunization) on day 7 both (lot number, strength and expiry date not reported) via unknown route in unknown administration site since they missed day 3 (routine immunisation schedule not administered) (unknown latency).  On an unknown date in 2025, the patient developed very sick (illness), hallucination, chest pains, firework feeling in their chest like a heart attack (chest pain) (palpitations), jump at sleep /could not sleep/insomnia (insomnia), lost 20 pounds (weight decreased), tremors in hands (tremor), anxiety, really bad ringing in my ears that persisted has been since the injection/tinnitus (tinnitus), could not eat (Feeding disorder) (unknown latency).  Relevant laboratory test results included: Weight decreased - On an unknown date in 2025:  [lost 20 pounds].  Reportedly, They had a bat in their kitchen and their doctor recommended that they get vaccination just in case. Patient stated that they got their vaccination around 11-Mar-2025. Since getting the 2nd dose, which they think was IMOVAX, they have been very sick and have been in and out of hospital. They said that it was hard to say if some of the side effects that they were experiencing could be due to the other medications they were put on due to the side effects they were experiencing. But the really bad ringing in my ears that persisted has been since the injection. The first 2 months were bad, they could not eat or sleep and experiencing tremors. They mention that they have never been vaccinated before and they have always been kind of hypochondriac. So that may be where the anxiety is from and may be it was their body being unused with vaccination.  Action taken was not applicable.  It was not reported if the patient received a corrective treatment for the events (illness, hallucination, chest pain, palpitations, insomnia, weight decreased, tremor, anxiety, tinnitus and eating disorder).  At time of reporting, the outcome was Unknown for the events (illness, eating disorder, weight decreased, chest pain and palpitations) and was not recovered/ not resolved for rest other events.  Seriousness criteria: The event (hallucination) was assessed as medically significant.   This suspected adverse reaction report is submitted and classified as a medication error solely and exclusively to ensure the marketing authorization holder's compliance with the requirements set out in the Directive 2001/83/EC and Module VI of the Good Pharmacovigilance Practices. The classification as a medical error is in no way intended, nor should it be interpreted or construed as an allegation or claim made by the marketing authorization holder that any third party has contributed to or is to be held liable for the occurrence of this medication error.; Sender's Comments: Sanofi company comment dated 15-Jul-2025: This case involves a 37 years old female patient who received 1st dose of Rabies vaccine inact (chick embryo) (Rabavert) on day 0 and 2nd dose of rabies (HDC) vaccine [Imovax rabies] on day 7 since they missed day 3 and had very sick, hallucinations, chest pains, firework feeling in their chest- like a heart attack, chest pains, jump at sleep/could not sleep/insomnia, lost 20 pounds, tremors in hands, anxiety, really bad ringing in my ears that persisted has been since the injection/tinnitus and could not eat. The time to onset was compatible with the role of vaccine. The clinical course of the event was not provided. Patient's past medical history of anxiety disorder cannot be ignored either. Furthermore, information regarding condition at the time of vaccination, lab data excluding other predisposing etiologies would be needed for complete assessment of the case. Based upon the reported information, the role of the suspect vaccine cannot be assessed