Sex: F
Vaccine: FLUX
Symptoms: Asthenia, Confusional state, Haemodialysis, Illness, Mental status changes
Clinical narrative: patient itched all the time; Patient was sick; Extreme mental status change; Confusion (severty 10); Weakness (severity 9 or 10); Nause (severity 5 or 6); This case was reported by a other health professional via other manufacturer and described the occurrence of mental status changes in a 86-year-old female patient who received Flu unspecified (Influenza vaccine) for prophylaxis.   Concurrent medical conditions included chronic kidney disease, hypertension, pruritus, parathyroid disorder, anxiety and blood disorder. Concomitant products included apixaban (Eliquis), hydroxyzine, labetalol, sevelamer carbonate (Renvela), cinacalcet hydrochloride (Sensipar) and alprazolam (Xanax).   On an unknown date, the patient received Influenza vaccine. On 5th October 2020, unknown after receiving Influenza vaccine, the patient experienced nausea. On 5th October 2022, the patient experienced mental status changes (serious criteria hospitalization), confusion (serious criteria hospitalization) and weakness (serious criteria hospitalization). On 6th October 2022, the patient experienced sickness. In 2022, the patient experienced pruritus. The patient was treated with hemodialysis dialysate solution. On an unknown date, the outcome of the mental status changes, confusion, weakness and nausea were recovered/resolved and the outcome of the sickness and pruritus were unknown.   It was unknown if the reporter considered the mental status changes, confusion, weakness, nausea, sickness and pruritus to be related to Influenza vaccine.     Additional Information:  add full form of date and rest things  exmple 26th September 2022  Additional Information: GSK receipt date: 09-DEC-2022 Reporters comment: The nurse reported that the patient received the influenza vaccine and korsuva and experienced mental status changes, asthenia, confusional state, and nausea. The patient stated that she did not experienced before The patient was not on medications for sleep, for pain, herbal products, to relax other than Xanax, for heart, to clear the mind or think more clearly, or to calm the nerves other than Xanax ' The patient d not used tobacco, nicotine, alcohol, or recreational drugs. There was no past surgeries. On 26th SEP 2022, in the morning between 8:30 am and 9 am post-hemodialysis treatment, the 105-pound patient initiated intravenous (IV) Korsuva 0.5 mL (lot number AP1692B; expiration date OCT 2023), three times a week for itching from chronic kidney disease(CKD). On 05th OCT 2022, the patient experienced extreme mental status change (reported as requiring hospitalization), nausea (severity 5 or6), weakness (severity 9 or 10), and confusion and had a flu shot. When nausea was observed, it was associated with Korsuva use. The patient was really weak and was helped to a chair. As per the reporter, the patient was vibrant" and could jump rope, so this was a drastic change. The patient was totally confused (severity10). The patient said that Korsuva did help her itching (severity 10); it was reported that the patient itched all the time and saw dermatologist. On 06th OCT 2022, the patient was confused and sick. The patient's daughter took her to the hospital and the patient was admitted. On 09th OCT 2022, the patient was discharged from the hospital. It was reported that the patient is back to herself. She was dialyzed for three days to get Korsuva out of her system. On 05th OCT 2022, around 8:30 am-9 am post-hemodialysis treatment, the patient had the last dose of Korsuva, and it was not restarted In OCT 2022, the events of extreme mental status change, weakness, confusion, and nausea resolved. No further information was provided. The nausea as related to Korsuva. The reporter was not sure if the events of extreme mental status change, weakness, confusion were related to Korsuva or the influenza vaccine. Additional Supportive information: The patient received co-suspect drug as Korsuva which was not get auto coded hence retain in narrative. In Oct 2022 the events of extreme mental status change, weakness, confusion, and nausea resolved