Age: 22.0
Sex: F
Vaccine: HPV4
Symptoms: Drug exposure during pregnancy, Herpes zoster, Ultrasound scan normal
Clinical narrative: Initial and follow up information has been received for the Pregnancy Registry for GARDASIL from a Registered Nurse (R.N.) concerning a 22 year old female patient who on 02-JUL-2007 was vaccinated with a first dose of GARDASIL lot #656050/0245U.  The nurse reported that patient received the injection during pregnancy.  No adverse reactions were reported.  Unspecified medical attention was sought by the patient.  In follow up information the doctor's office reported that patient had shingles approximately at 26 weeks of her pregnancy.  She had ultrasound x3 was done and they were reported as normal.  On 28-FEB-2008 she delivered a female normal baby 39 weeks from her last menstrual period.  The baby weighed 6 lb 8 oz and was 21 inches in length.  Her Apgar score was 8/9.  There was no congenital abnormalities reported.  Additional information is not expected. Pediatric medical records were received and reviewed concerning a female normal infant which reported the following: On 07-MAR-2008 the one week old infant weighted  9 7 pounds and 4 ounces. The physical exam and development were normal. On 17-MAR-2008 the infant weighted 7 pounds 12 ounces with clothes. Patient had stuffy nose, no fever and also white cuating of tongue which was diagnosed as thrush and URI. Heart and lung examinations were negative. Abdomen, nott. The infant was treated with saline nose drops and nystatin suspension 60 ml, 1 ml QD. On 08-APR-2008 the approximately 2 month old infant weighted 9 pounds 2 ounces with clothes. Her height was 22.5 inches. Infant is doing well except for thrush. Ear, nose, throat (ENT) examination showed tongue coated white. Heart and lung examinations were negative. Abdomen soft. Infant continued with nystatin suspension treatment. On 22-APR- 2008 lab and diagnostic test from the newborn screening lab report were within normal limits. The patient still had thrush. On 09-MAY-2008 the approximately 2 month old female infant was vaccinated with PEDIARIX, PREVNAR. The infant with age appropriate growth and development weighted: 12 pounds. Height: 24 inches, and (FOC): 41.4. Physical exam revealed positional plagiocephaly (infant was encourged to look towards left) and constipation. Reinforced safe sleep practices, supervised (tummy time) were recommended. Also 1 ounce of prune juice added to 1 or 2 bottles of formula per day was recommened. In June 2008, the approximately 3 month old infant with age appropriate growth and development weighted 15 pounds and 1 ounce. Height : 25.5 inches and FOC: 43.0. Physical exams were normal. Ocassional constipation was noted. Reinforced safe sleep practices supervised were recommended (tummy time). On 19-JUN-2008, mild eczema-like rash was noted on left cheek treated with EUCERIN. On 15-JUL-2008 the approximately 4 month and a half old infant was vaccinated with PEDIARIX, PREVNAR. Weight: 16 pounds. Height: 26.25 inches and FOC: 44.4. Physical and development exams were normal. As stated above, the infant experienced constipation, mild eczema-like rash on left cheek while on therapy with Hib conj vaccine (OXPC) (MSD) (WAES 089USA01524). No further information is available.