Sex: M
Vaccine: VARZOS
Symptoms: Disorientation, Fatigue, Feeling of body temperature change, Influenza like illness, Nausea
Clinical narrative: pimple on the vein line; pimples like blisters on his right upper arm; scars; swelling along the vein line; is still sluggish; not as active as he was prior to the second shot; shingles rash; flu-like symptoms; feeling hot and cold; could not get warm; weakness / lack of energy; feeling shaky; night sweats; disoriented; nausea; extreme tiredness; This case was reported by a consumer via call center representative and described the occurrence of vesicular rash in a 74-year-old male patient who received Herpes zoster (Shingrix) (batch number 5H42H, expiry date 19th March 2022) for prophylaxis.   Previously administered products included Shingrix (1st dose received on 26th September 2019 with batch number 3D57E and expiry date 22th November 2021.).   On 11th December 2019, the patient received the 2nd dose of Shingrix (intramuscular). On 13th December 2019, 2 days after receiving Shingrix and an unknown time after starting Valacyclovir, the patient experienced influenza-like symptoms, feeling hot and cold, anhidrosis, weakness, shaky feelings, night sweat, disorientation, nausea and tiredness. On 16th December 2019, the patient experienced vesicular rash. On 13th January 2020, the patient experienced swelling. In January 2020, the patient experienced sluggishness and underactive. On an unknown date, the patient experienced pimples, blister and scar. The patient was treated with valaciclovir hydrochloride (Valacyclovir). On an unknown date, the outcome of the vesicular rash was resolved with sequelae and the outcome of the influenza-like symptoms, feeling hot and cold, anhidrosis, weakness, shaky feelings, night sweat, disorientation and nausea were recovered/resolved and the outcome of the tiredness was not recovered/not resolved and the outcome of the swelling, pimples, sluggishness, underactive, blister and scar were unknown.   It was unknown if the reporter considered the vesicular rash, influenza-like symptoms, feeling hot and cold, anhidrosis, weakness, shaky feelings, night sweat, disorientation, nausea, tiredness, swelling, pimples, sluggishness, underactive, blister and scar to be related to Shingrix.  Additional case details were reported as follows: The patient developed a straight-line rash of 5 pimples like blisters on his right upper arm between his elbow & shoulder.  The rash subsided, but he had scars where the blisters were.  He was still feeling weak and tired at the time of reporting. On 13th January 2020, three days before date of reporting he broke out again with a rash, which he described as large rash that appears like shingles, and there is swelling along the vein line.  On 15th January 2020 he had another pimple on the vein line.  He saw his family doctor on 14th January, that couldn't determine if it was shingles or not.  He was going to a dermatologist on 16th January 2020 and he will call back if it was shingles.  The patient noted that he wasn't still himself since getting the 2nd dose.  The patient was still sluggish and not as active as he was prior to the 2nd dose. On 19 December 2019, he had an appointment with his physician assistant and was prescribed Valacyclovir 1 G three times per day for 7 days.  The reporter consented to follow up.