Sex: F
Vaccine: COVID19, UNK
Symptoms: Ageusia, Nasal congestion, SARS-CoV-2 test
Clinical narrative: Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive; Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive; This spontaneous case was reported by a patient and describes the occurrence of NASAL CONGESTION (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive) and AGEUSIA (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive) in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 03B21A) for COVID-19 vaccination.    Co-suspect product included non-company product NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment.    The patient's past medical history included Ankle injury and Hip injury. Previously administered products included for Product used for unknown indication: Lidocaine and Pencillin. Past adverse reactions to the above products included Allergy with Lidocaine and Pencillin. Concurrent medical conditions included Asthma, Inflammation (due to ankle and hip injury) and Thyroid disorder. Concomitant products included LEVOTHYROXINE for Thyroid disorder.   On 01-Sep-2021 at 9:00 AM, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 03-May-2022, the patient started NIRMATRELVIR, RITONAVIR (PAXLOVID) (unknown route) at an unspecified dose. On 11-May-2022 at 4:00 AM, the patient experienced NASAL CONGESTION (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive) and AGEUSIA (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive). At the time of the report, NASAL CONGESTION (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive) and AGEUSIA (Post paxlovid: increase in nasal congestion and complete loss of taste!14 days out since first test, still testing positive) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 02-May-2022, SARS-CoV-2 test: positive (Positive) Positive. On an unknown date, SARS-CoV-2 test: positive (Positive) Positive.         It was reported that the patient was taking other medications/products within 2 weeks of starting COVID-19 treatment. The patient had previously received COVID-19 vaccine.  The device date was reported as 15-May-2022. Company comment: This spontaneous case concerns a 59-year-old, female patient with no relevant medical history, who experienced the unexpected, non-serious AESI of Ageusia. The event occurred 252 days after administration of second dose of mRNA-1273. On May 2, 2022, SARS-CoV-2 test was done which revealed a positive result. There was no information regarding the first dose. Details of concomitant medications, medical history, clinical course, treatment and outcome were not provided. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a 59-year-old, female patient with no relevant medical history, who experienced the unexpected, non-serious AESI of Ageusia. The event occurred 252 days after administration of second dose of mRNA-1273. On May 2, 2022, SARS-CoV-2 test was done which revealed a positive result. There was no information regarding the first dose. Details of concomitant medications, medical history, clinical course, treatment and outcome were not provided. The benefit-risk relationship of mRNA-1273 is not affected by this report.