Age: 52.0
Sex: F
Vaccine: COVID19
Symptoms: Formication, Paraesthesia, Pruritus, Rash, Urticaria
Clinical narrative: Felt itchy on my wrists/ Itching has gotten worse/ itched terribly; Little bumps began to appear/  noticed more and more bumps/hives just lighting up my torso area; Feels like she is crawling out of her skin.; Breaking out with a rash/the rash started on my neck and went down to my upper thighs; It felt as if needles were trying to poke from my insides out; This spontaneous case was reported by a consumer and describes the occurrence of PRURITUS (Felt itchy on my wrists/ Itching has gotten worse/ itched terribly), FORMICATION (Feels like she is crawling out of her skin.), URTICARIA (Little bumps began to appear/  noticed more and more bumps/hives just lighting up my torso area), PARAESTHESIA (It felt as if needles were trying to poke from my insides out) and RASH (Breaking out with a rash/the rash started on my neck and went down to my upper thighs) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 036B21A and 027A21A) for COVID-19 vaccination.     Concurrent medical conditions included Penicillin allergy. Concomitant products included ESTRADIOL (ESTROGEN), PROGESTERONE and ROSUVASTATIN for an unknown indication.   On 07-Mar-2021 at 11:15 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 04-Apr-2021 at 11:30 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 11-Apr-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced RASH (Breaking out with a rash/the rash started on my neck and went down to my upper thighs). On 12-Apr-2021, the patient experienced FORMICATION (Feels like she is crawling out of her skin.). On 14-Apr-2021 at 8:00 AM, the patient experienced PRURITUS (Felt itchy on my wrists/ Itching has gotten worse/ itched terribly). 14-Apr-2021 at 8:00 AM, the patient experienced URTICARIA (Little bumps began to appear/  noticed more and more bumps/hives just lighting up my torso area). In April 2021, the patient experienced PARAESTHESIA (It felt as if needles were trying to poke from my insides out). The patient was treated with FAMOTIDINE (PEPCID [FAMOTIDINE]) for Adverse event, at an unspecified dose and frequency; DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency; CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency and MONTELUKAST SODIUM (SINGULAIR) for Adverse event, at an unspecified dose and frequency. At the time of the report, PRURITUS (Felt itchy on my wrists/ Itching has gotten worse/ itched terribly), FORMICATION (Feels like she is crawling out of her skin.), URTICARIA (Little bumps began to appear/  noticed more and more bumps/hives just lighting up my torso area) and PARAESTHESIA (It felt as if needles were trying to poke from my insides out) was resolving and RASH (Breaking out with a rash/the rash started on my neck and went down to my upper thighs) had resolved. Not Provided          The patient reported that the events began the same way (as with first dose). She felt itchy on wrists and little bumps began to appear. This time, the itching was more severe.  She noticed more and more bumps/hives just lighting up her torso area. The rash started on neck and went down to upper thighs. She started diphenhydramine immediately and was taking them every 2 hours at the itching was far more intense than the first time. The patient visited an urgent care. She was prescribed Montelukast, cetirizine, famotidine and advised that she could continue diphenhydramine as needed. She was given a prescription for a steroid, however was told not to fill it until two weeks was up after the vaccine. She had no relief by the next morning and visited her primary care physician. Later, she called CVS and was told to use cold compresses and not to take any over the counter medication. At that point, she felt that if she could have ripped all of her skin off, she would have. It felt as if needles were trying to poke from  insides out and itched terribly. She did not follow their advice and continued with the meds. Finally, she contacted a friend who was a physician, and he said to immediately fill the steroid prescription. She did that and about 5-6 days later she felt a lot better and the rash had faded.   This case was linked to MOD-2021-074802 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 04-May-2021: Additional information included patient demographic details, medical history, concomitant medications, new events along with event description and treatment details.