chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 45.0
Sex: U
Vaccine: FLU3
Symptoms: Injection site erythema, Injection site paraesthesia, Injection site swelling
Clinical narrative: Case number PHEH2016US022333 is an initial spontaneous report received from other healthcare professional on 31 Aug 2016. This report refers to 45 year old patient of unknown gender. Medical history and concomitant medications were not reported. The patient was vaccinated with FLUVIRIN (batch number: 1618401) at a dose of 0.5 ml intradermal on 29 Aug 2016. On the same day, after administration patient developed redness, tingling and swelling at injection site. The adverse event was ongoing, but slowly improving. The outcome of events was improving. The seriousness of the events was reported as non serious. The causality of events was not reported.
Sex: U
Vaccine: FLU3
Symptoms: Incorrect route of drug administration, No adverse event
Clinical narrative: Case number PHEH2015US026565, is an initial spontaneous report received from a pharmacist on 03 Dec 2015. This report refers to a patient of an unknown age and gender. Past medical history and concomitant medication were not reported. The patient was vaccinated with FLUVIRIN (batch number: not reported) subcutaneously instead of intramuscularly on an unknown date. No adverse event was reported following this administration error.
Sex: F
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026498, is an initial spontaneous report received from a pharmacist on 16 Dec 2015. This report refers to a female patient of an unknown age. Medical history was not reported. Concomitant medication was not reported. The patient vaccinated with prefilled syringe FLUVIRIN (batch number, expiry date: not reported) on an unknown date; that was out of temperature range at 53 Fahrenheit for 8 hours. No adverse event reported following this administration error (incorrect storage of drug).
Age: 43.0
Sex: F
Vaccine: FLU4
Symptoms: Immediate post-injection reaction, Insomnia, Musculoskeletal pain, Myalgia
Clinical narrative: At the time of the injection, the patient felt as though it was not right because her muscle instantly burned. A month later, her shoulder is aching and in severe pain. She cannot sleep at night and has never had any pain in her left shoulder in the past. She is considering seeking medical attention to address these concerns.
Sex: F
Vaccine: FLU3
Symptoms: Injected limb mobility decreased, Pain in extremity
Clinical narrative: Case number PHEH2015US025929, is an initial spontaneous report received from a healthcare professional on 09 Dec 2015. This report refers to a 60-years-old female patient. Past medical history and concomitant medication were not reported. The patient was vaccinated with FLUVIRIN (batch number: 15735P and expiry date: not reported) on an unknown date. The patient reported that she experienced soreness and trouble moving the arm that was injected on 07 Oct 2015. The outcome of the events was reported as complete recovery on 07 Oct 2015. The seriousness and causality of the events was not reported.
Age: 34.0
Sex: M
Vaccine: FLU3
Symptoms: Dizziness, Fatigue
Clinical narrative: Case number PHEH2015US023060, is an initial spontaneous report received from a pharmacist on 06 Nov 2015. This report refers to a 34 year old male patient. Past medical history and concomitant medications were not reported. The patient was vaccinated with FLUVIRIN (batch number: 1515001) on 29 Oct 2015. On the following day after vaccination on 30 Oct 2015 the patient experienced fatigue and dizziness and it was getting progressively worse at the time of this report. Outcome of the event was reported as condition unchanged. Event was reported as non serious and causality was not reported.
Age: 66.0
Sex: F
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026833, is a spontaneous report initially received from a nurse on 22 Dec 2015. This report refers to a 66-year-old female patient. Medical history was not reported. Concomitant medication was not reported. The patient was vaccinated with FLUVIRIN (batch number: 1514501, expiry date: May 2016) into right deltoid on 07 Oct 2015. It was reported that FLUVIRIN administered to the patient had a temperature excursion of 34 degrees. The reporter stated that she did not know why the refrigerator was out of temperature range for an unspecified amount of time overnight. She checked the temperature before she left for the day and when she arrived the next day and the temperature was fine. It was a new refrigerator and there have not been any problems since the temperature excursion. No adverse reaction was experienced by the patient following the maladministration. No further information was provided. Follow up information received from the nurse on 26 Jan 2016: Reporter comment updated.
Sex: U
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026446, is an initial spontaneous report received from a nurse on 08 Dec 2015. This report refers to a patient of an unknown age and an unknown gender. Medical history was not reported. Concomitant medication was not reported. The patient vaccinated with FLUVIRIN (batch/lot number: 1515701/ 1516601, expiry date: Jun 2016) on 08 Dec 2015 which was stored out of temperature range at 33 Fahrenheit for 6 days and 30 minutes. The reporter stated that their refrigerator thermometer had not been calibrated for 5 years. No adverse event was reported as following medication errors.
Age: 46.0
Sex: M
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US025825, is a spontaneous report initially received from a health care professional on 07 Dec 2015. This report refers to a 46 years old male patient. Medical history and concomitant medications were not reported. The patient tolerated vaccine in past. The patient was vaccinated with FLUVIRIN PFS (batch number: 158301) intramuscularly into left deltoid at a dose of 0.5 ml (prefilled) on 06 Dec 2015. It was reported FLUVIRIN was administered to patient after 5 hours of power outage of refrigerator and possible temperature excursion. No recorded temperatures were reported. No adverse event was reported. Follow up received from a health care professional on 29 Jan 2016: Updated Vaccine application site and dose and narrative updated accordingly.
Age: 63.0
Sex: M
Vaccine: FLU3
Symptoms: Pruritus, Urticaria
Clinical narrative: Case number PHEH2016US001765, is a combine initial spontaneous report received from a consumer (patient and patient's wife) on 20 Jan 2016. This report refers to a 63-year-old male patient. Medical history was not reported. Concomitant medication included irbesartan (manufacturer unknown), citalopram (manufacturer unknown), fenofibrate (manufacturer unknown), ranitidine (manufacturer unknown), allopurinol (manufacturer unknown) and atorvastatin (manufacturer unknown). The patient was vaccinated with FLUVIRIN (batch number: not reported) intramuscularly on 14 Jan 2016. On 14 Jan 2016 later that night, the patient woke up and told his wife that something was wrong, he had hives with no fever/hives and welts all over his torso, according to his wife the welts got bigger to the size of quarters and complained of itching. The patient was treated with O2 BENADRYL tablet. The outcome of the event hives was reported as complete recovery after few hours and for other event it was reported as condition improving (symptoms subsided). The seriousness and causality of the events was not reported.
Age: 31.0
Sex: F
Vaccine: FLU3
Symptoms: Incorrect product storage
Clinical narrative: Case number PHEH2015US026842, is an initial spontaneous report received from a nurse on 22 Dec 2015. This report refers to a 31 year old female patient. Medical history was not reported. Concomitant medication was not reported. The patient was vaccinated with FLUVIRIN (batch number: 1514501, expiry date: May 2016) into left deltoid on 19 Oct 2015. It was reported that before administration the FLUVIRIN had a temperature excursion of 34 degrees. The reporter stated that she did not know why the refrigerator was out of temperature range for an unspecified amount of time overnight. She checked the temperature before she left for the day and when she arrived the next day and the temperature was fine. It was a new refrigerator and there have not been any problems since the temperature excursion. No adverse reaction was experienced by the patient following the maladministration. No further information provided. Follow up information received from the nurse on 26 Jan 2016: Reporter's comment updated.
Age: 31.0
Sex: F
Vaccine: FLU3
Symptoms: Exposure during pregnancy, No adverse event, Wrong drug administered
Clinical narrative: Case PHEH2016US23135 is an initial spontaneous report received from pharmacist on 08 Sep 2016. This report refers to 31 year old pregnant female patient. Past medical history and concomitant medication was not reported. The patient was vaccinated with single dose of FLUVIRIN (batch number: 1618701) at a dose of 0.5 ml intramuscular on 07 Sep 2016. It was reported that, the patient who was 16 week pregnant received MDV vaccine instead of FLUVIRIN PFS. The patient was still onsite when she called and spoke with reporter and had demonstrated no adverse events. After administration the vaccine the pharmacist later realized that the ACIP (Advisory Committee on Immunization Practices) advised to use the preservative free and reporter wanted to see if safety data was available regarding FLUVIRIN and pregnancy. No adverse event was reported following this vaccine exposure during pregnancy.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site rash, Pruritus, Pyrexia
Clinical narrative: Case number PHEH2016US020175 is an initial spontaneous report received from pharmacist on 09 Aug 2016. This report refers to 52 year old female patient. Medical history and concomitant medication was not reported. The patient was vaccinated with FLUVIRIN (Expiry date: not reported, batch number: 1618701), intramuscularly at a dose of 0.5 ml into the left arm on 08 Aug 2016. On the same day, the patient had mild fever, localized rash in the left arm at injection site and itching that occurred about 15 to 20 minutes after injection. The outcome of events was reported as unknown. The seriousness of the event was not reported. Causality of events was reported as suspected.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Incorrect route of drug administration, Injection site erythema, Injection site pruritus, Vaccination site swelling
Clinical narrative: Case number PHEH2015US025341 is an initial spontaneous report received from a nurse on 02 Dec 2015. This report refers to a 52 year old female patient. Past medical history and concomitant medications were unknown. She was vaccinated with FLUVIRIN (batch number: 1516401) via intradermal route at a dose of 0.5 ml on 30 Nov 2015. She experienced redness, swelling and itching at the vaccination site on an unknown date. She was given lidocaine/hydrocortisone cream. The events outcome was unknown. The events were reported as non-serious. The causality of the events was not reported.
Age: 12.0
Sex: F
Vaccine: HPV9
Symptoms: Sinusitis
Clinical narrative: This spontaneous report was received from a Licensed Vocational Nurse, concerning her daughter, a 12 year old female patient. Aside from seasonal allergies, the patient had no other reactions or allergies. In August 2016, the patient was vaccinated with a first dose of GARDASIL 9 for prophylaxis (dose, route of administration, lot number and expiration date were not reported). Concomitant therapies included cetirizine hydrochloride (ZYRTEC). In late October 2016, the patient experienced a sinus infection (sinusitis). She received an antibiotic, azithromycin (Z-PAK), and recovered from the event after three days. The patient received the second dose of GARDASIL 9 (dose, route of administration, lot number and expiration date were not reported) on November 2016 and did not experience any further adverse events.   The reporter did not assess the relatedness between therapy with GARDASIL 9 and the sinus infection. No product quality complaint was involved. Additional information has been requested.
Sex: U
Vaccine: VARZOS
Symptoms: Expired product administered, No adverse event
Clinical narrative: This spontaneous report was received from a nurse referring to a patient of unknown age and gender. The patient's medical history, concurrent conditions and concomitant therapies were not reported. On 10-JAN-2017, the patient was vaccinated with an expired dose of ZOSTAVAX, with lot # L038926 and expiration date 06-JAN-2017 (dose and route of administration were not provided), for prophylaxis. No adverse events were reported. There was no a product quality complaint (PQC) involved. Additional information has been requested.
Sex: F
Vaccine: VARZOS
Symptoms: Cancer in remission, Leukaemia
Clinical narrative: This spontaneous report as received from a pharmacist refers to a currently 60 year old female patient. The patient's medical history or concurrent conditions were not reported. On an unspecified date in 2011, the patient was vaccinated with ZOSTAVAX (lot#/exp. date, dose and route of administration were not provided). Concomitant therapy included warfarin. On an unspecified date at some point in 2011, the patient was hospitalized related to Leukemia; however she was diagnosed on an unspecified date in 2013 with Leukemia. No treatment was given to the patient. It was reported that the patient recovered from Leukemia on an unspecified date. At the time of the report the patient was in remission from cancer. There was no significant disability or incapacity, nor the event was considered life threatening or overdose and no PQC was involved. Upon internal review the event Leukemia was considered to be Medically significant. The relatedness of the event with ZOSTAVAX was not provided. Additional information has been requested.
Sex: U
Vaccine: PNC13
Symptoms: Hypersensitivity, Urticaria
Clinical narrative: This is a spontaneous report based on information received by Pfizer from Merck, manufacturer control number 00318555. A contactable pharmacist reported for a patient of an unknown age, gender and race that received PREVNAR 13 for immunization at single dose on unknown date. On unknown date the patient experienced allergy reaction of hives. The outcome of the events was unknown. No follow up attempts possible. No further information expected.
Sex: F
Vaccine: PNC13, PNC13
Symptoms: Adverse reaction, Asthenia, Feeling abnormal
Clinical narrative: This is a spontaneous report from a contactable consumer who reported for herself, via Pfizer-Sponsored Program IBCC (Inbound Call Center for HCPs). A female patient of an unspecified age, received the second dose of PREVNAR 13, on an unspecified date at 0.5 ml single for immunisation.  The patient medical history and concomitant medications were not reported. The patient received two shots of pneumococcal 13-val conj vaccine within six months of period: the doses were administered by two different doctors and the patient thought she would not have to receive the second one. On an unspecified date the patient experienced really bad severe symptoms and reactions, she felt like she was getting weak and dying. The outcome of the events was unknown.
Sex: F
Vaccine: PNC13, PNC13
Symptoms: Asthenia, Cough, Decreased appetite, Dry skin, Listless
Clinical narrative: This is a spontaneous report from a contactable consumer who reported for herself, via Pfizer-Sponsored Program IBCC (Inbound Call Center for HCPs). A female patient of an unspecified age, received the second dose of PREVNAR 13, on an unspecified date at 0.5 ml single for immunisation.  The patient medical history and concomitant medications were not reported. The patient received two shots of pneumococcal 13-val conj vaccine within six months of period: the doses were administered by two different doctors and the patient thought she would not have to receive the second one. On an unspecified date the patient experienced really bad severe symptoms and reactions, she felt like she was getting weak and dying. The outcome of the events was unknown.
Sex: F
Vaccine: PNC13, PNC13
Symptoms: Malaise, Respiratory tract congestion, Weight decreased
Clinical narrative: This is a spontaneous report from a contactable consumer who reported for herself, via Pfizer-Sponsored Program IBCC (Inbound Call Center for HCPs). A female patient of an unspecified age, received the second dose of PREVNAR 13, on an unspecified date at 0.5 ml single for immunisation.  The patient medical history and concomitant medications were not reported. The patient received two shots of pneumococcal 13-val conj vaccine within six months of period: the doses were administered by two different doctors and the patient thought she would not have to receive the second one. On an unspecified date the patient experienced really bad severe symptoms and reactions, she felt like she was getting weak and dying. The outcome of the events was unknown.
Age: 66.0
Sex: M
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026837, is an initial spontaneous report received from a nurse on 22 Dec 2015. This report refers to a 66-year-old male patient. Medical history was not reported. Concomitant medication was not reported. The patient was vaccinated with FLUVIRIN (batch number: 1514501, expiry date: May 2016) into left deltoid on 07 Oct 2015. It was reported that FLUVIRIN administered to the patient had a temperature excursion of 34 degrees. The reporter stated that she did not know why the refrigerator was out of temperature range for an unspecified amount of time overnight. She checked the temperature before she left for the day and when she arrived the next day and the temperature was fine. It was a new refrigerator and there have not been any problems since the temperature excursion. No adverse reaction was experienced by the patient following the maladministration. No further information provided. Follow up information received from the nurse on 26 Jan 2016: Reporter's comment updated.
Age: 57.0
Sex: F
Vaccine: FLU3
Symptoms: Pain in extremity
Clinical narrative: Case number PHEH2016US012414 is an initial spontaneous case received from consumer on 16 May 2016. This report refers to a 57 year old female patient. Medical history and concomitant medication were not reported. The patient was vaccinated with FLUVIRIN (batch number: 1515001, expiry date: May 2016) on left arm on an unknown date. On an unspecified date, the patient was suffering from pain in the entire left arm since vaccination. It was unknown if customer want to pursue a claim for this incident. The outcome of event was not reported. The seriousness and causality of event were not reported. Follow up information received from consumer on 26 Jul 2016: Added physician details.
Age: 71.0
Sex: M
Vaccine: FLU3
Symptoms: Pain in extremity
Clinical narrative: Case number PHEH2016US008122, is an initial spontaneous report received from a health care professional via pharmacy on 01 Apr 2016. This report refers to a 71 years old male patient. Historical condition was not reported. Current conditions included asthma, aspirin allergy and epilepsy. Concomitant medication included KEPPRA. The patient received FLUVIRIN (lot number: 1516001, expiry date: 30 Jun 2016) at a dose of 0.5 ml intramuscularly into left arm on an unknown date. Since the vaccination the patient experienced pain in upper right arm. The outcome of the event was unknown. The seriousness and causality was not reported.
Age: 29.0
Sex: F
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026848, is a spontaneous report initially received from a nurse on 22 Dec 2015. This report refers to a 29 year old female patient. Past medical history and concomitant medication were not reported. The patient was vaccinated with FLUVIRIN (batch number: 1514501 and expiry date: May 2016) into right deltoid on 07 Oct 2015 which was stored out of recommended temperature range (temperature excursion at 34 degrees). The reporter stated that she did not known why the refrigerator was out of temperature range for an unspecified amount of time overnight. She checked the temperature before she left for the day and when she arrived the next day and the temperature was fine. It was a new refrigerator and there were not problems since the temperature excursion. No adverse event was reported following this medication errors. Follow up information received via nurse on 26 Jan 2016: Reporter's comments updated.
Age: 4.0
Sex: U
Vaccine: FLU3
Symptoms: Drug administered to patient of inappropriate age, No adverse event
Clinical narrative: Case number PHEH2015US025669 is an initial spontaneous report received from a health care professional on 30 Nov 2015. This report refers to a patient of age under 4 years old and unknown gender. Medical history and concomitant medication were not reported. The patient was vaccinated with FLUVIRIN (batch number: not reported) intramuscularly on an unknown date. No adverse event was reported following this medication error.
Sex: U
Vaccine: FLU3
Symptoms: Incorrect dose administered, No adverse event, Underdose
Clinical narrative: Case number PHEH2015US023047, is an initial spontaneous report from a health care professional received on 04 Nov 2015. This report refers to a patient of an unknown age and gender. Medical history and concomitant medications were not reported. The patient vaccinated with FLUVIRIN (batch number: 1515201) inadvertently at a dose of 0.05 ml intramuscular on 30 Oct 2015. No adverse event was reported following this maladministration.
Age: 61.0
Sex: F
Vaccine: FLU3
Symptoms: Incorrect product storage, No adverse event
Clinical narrative: Case number PHEH2015US026836 is a spontaneous report initially received from a nurse on 22 Dec 2015. This report refers to a 61-year-old female patient. Medical history was not reported. Concomitant medication was not reported. The patient was vaccinated with FLUVIRIN (batch number: 1514501, expiry date: May 2016) into left deltoid on 07 Oct 2015. It was reported that FLUVIRIN administered to the patient had a temperature excursion of 34 degrees. The reporter stated that she did not know why the refrigerator was out of temperature range for an unspecified amount of time overnight. She checked the temperature before she left for the day and when she arrived the next day and the temperature was fine. It was a new refrigerator and there have not been any problems since the temperature excursion. No adverse reaction was experienced by the patient following the maladministration. No further information provided. Follow up information received from the nurse on 26 Jan 2016: Reporter's comment updated.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Chills, Influenza A virus test positive, Influenza B virus test positive, Pain, Pyrexia
Clinical narrative: Case number PHEH2015US024500 is an initial spontaneous report received from a consumer on 20 Nov 2015. This report refers to a 62 year old female patient. Medical history and concomitant medications were not reported. The patient was vaccinated with FLUVIRIN (batch number: 157904) intramuscularly on 16 Nov 2015. It was reported that after five hours of vaccination the patient experienced chills, fever, aches and pain. She visited physician on 18 Nov 2015, where they confirmed positive for influenza A and B virus. The outcome of the events was reported as condition improving. The seriousness and causality of the events were unknown.
Age: 25.0
Sex: M
Vaccine: FLU3
Symptoms: No adverse event, Underdose
Clinical narrative: Case number PHEH2016US022697 is an initial spontaneous report received from a pharmacist on 06 Sep 2016. This report refers to 26 year old male patient. Past medical history and concomitant medications were not reported. The patient was vaccinated with single dose of FLUVIRIN (batch number: 1618901, expiry date: Apr 2017) at dose of 0.5 ml intramuscular on 03 Sep 2016. It was reported that, the patient received partial dose of FLUVIRIN. No adverse event was reported following this medication error.
Age: 37.0
Sex: F
Vaccine: FLU3
Symptoms: Exposure during pregnancy, No adverse event
Clinical narrative: Case number PHEH2016US005485 is an initial spontaneous report from the pharmacist received on 02 Mar 2016. This report refers to a 37 years old pregnant female patient. Patient's last menstrual date was not reported. It was reported that the patient who was expecting was vaccinated with FLUVIRIN (batch number: 15731P) on 02 Mar 2016. No adverse event was reported following vaccine exposure during pregnancy. Upon follow up reporter's new address was not found while searching on internet. Upon further follow up reporter's complete address was found while on internet search. Follow up report received on 14 Apr 2016: Added lost to follow up comment. Follow up report received on 19 Apr 2016: Updated reporters address and removed lost to follow up comment from narrative.
Sex: U
Vaccine: FLU3
Symptoms: Asthenia, Hot flush, Urticaria
Clinical narrative: Case number PHEH2016US004426, is an initial spontaneous report received from a consumer via Claims Management Services on 22 Feb 2016. This report refers to a patient of an unknown age and gender. Medical history and concomitant medications were not reported. The patient was vaccinated with FLUVIRIN (batch number: 1516601, expiry date: Jun 2016) on an unknown date. On an unknown date, the patient developed sustained ongoing reactions such as welts, hot flushes and weakness after the vaccine was administered. The patient was still under the care of physician. The outcome of the events was condition unchanged (sustained ongoing). The seriousness and causality of the events was not reported.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Adenovirus test, Allergy test, Ammonia normal, Anti-GAD antibody, Anti-NMDA antibody
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Bacterial test negative, Bartonella test negative, Blood culture negative, Blood immunoglobulin A normal, Blood immunoglobulin G normal
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Blood immunoglobulin M normal, Bordetella test negative, Borrelia test negative, Brain natriuretic peptide increased, CSF culture negative
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: CSF glucose normal, CSF protein decreased, CSF red blood cell count positive, CSF test normal, CSF white blood cell count negative
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Candida test positive, Clostridium test negative, Clostridium test positive, Continuous positive airway pressure, Corynebacterium test positive
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Crying, Culture urine negative, Cyanosis, Cytomegalovirus test negative, Diarrhoea
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Dyspnoea, Echocardiogram abnormal, Ejection fraction decreased, Ejection fraction normal, Electroencephalogram abnormal
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.
Age: 1.0
Sex: F
Vaccine: HEPA, MMR, VARCEL
Symptoms: Encephalitis viral, Endotracheal intubation, Enterovirus test negative, Epilepsy, Epstein-Barr virus test negative
Clinical narrative: 8/23/2016: 1 yo female received routine vaccines: MMR lot# M008588, VAR lot # M019643; and Hep A lot at Z5DM2. 8/29/2016 (day 6): that evening, child had mild fever of 100.8 with several episodes diarrhea, and fussy. Symptoms resolved with MOTRIN and calming. 8/30/2016: 2AM: hot sweaty Temp 100.8F given MOTRIN, fever gone 530am. Took flight and she slept a lot, felt warm, given dose MOTRIN around 11am. During ride to friends home, she was hot to touch, sleepy, lethargic but would awaken acting normal-laughing. About 3pm (out shopping) mom noted her head turn sideways, pupils dilated, body stiffened-was tense and she began to tremble/twitch-seizure. 911 contacted and child removed from car seat, skin was red about chest/torso-cooled with tepid water/remove clothing and within 5 minutes the trembling stopped. EMS arrived: child was sleepy and unresponsive (not awake). Mom said EMS advised temp 102.4F, her lips blue, eyes bloodshot, and child stopped breathing/gasping and required BVM support. 8/30/2016 (day 7) Arrival ER: seized with tonic/clonic movements - given Lorazepam 2mg. Appeared post ictal, agonal breathing after lorazepam = intubated. Temp 103F and HR 240, Given TYLENOL, Ceftriaxone and 40cc/kg IVF with HR 170 - admitted, extubated. Labs: mild transaminitis and hepatitis. 8/3/2016: after a bath, pale/cool lethargic, HR 220 vagal maneuvers ineffective, given multiple doses of adenosine 0.6 mg/kg total w/o resolution. 9/1/2016: cardiology evaluation; child now alert crying vigorously, good pulses with spontaneous resolution SVT, HR 200-150 x 1 hr then SVT again. Treated Adenosine, milrinone diagnosed myocarditis. While in the PICU - developed ITP. 9/2/2016: on HFNC and CPAP; troponin (9/3/16 peaked at 1.48) and BNP elevated. DX myocarditis; steroids x2 days; 9/3/2016: MRI suggests viral encephalitis. 9/4/2016: In PICU: jaw locked up, became tense and hemiparetic moving only right arm, re-intubated - resolved with phenobarbital MRI normal. 9/6/2016 Treated with IVIG and pulse steroids. 9/8/2016 no seizure x 1 week. Extubated. ? problem with vision and hearing after extubated. Child not recognizing parents; noted to no longer blink to threat, fix or follow with concern for loss of vision after extubated and became more aware of surroundings. Fine and gross motor deficits were noted by the hospital therapists with recommendations for ongoing OT and PT.