Age: 38.0
Sex: F
Vaccine: COVID19
Symptoms: Computerised tomogram thorax normal, Decreased appetite, Diarrhoea, Fibrin D dimer increased, Flushing
Clinical narrative: Moderna shot #2: About 6-8 hours in, I got the expected serious joint aches, chills, headache, and fever (101F). This lasted for about 2 days, managed well by alternating Motrin and Tylenol. A mild rash occurred a few days after shot #2.   Thought I was done since most of my colleagues bounced back after 2-3 days. Then 48 hours in, I developed a racing heart (HR in the 110-120s), sweating palms/soles, tingling/numbness in the feet/arms, warm flushes over my chest, nausea, and a few loose stools. No position or relaxation method would resolve these symptoms. All I could do was lie down perfectly still with an ice pack on my forehead and hope this was short-lived and would pass. I could not sleep. I had no appetite. Over the 8 days this has been occurring, I lost 3 pounds.  I could not find any literature of anyone else having any cardiac/dysautonomia symptoms. It scared me. I have no prior cardiac history and no history of anxiety. I went to the ER. Labwork showed an elevated D-dimer (luckily the CT scan showed NO blood clots), elevated WBC/neutrophils, and low potassium. Thyroid labs (which I had tested a few days later) were normal. The ER assumed the abnormal labs were due to the immune response to the vaccine and referred me to a cardiologist.   I did a virtual visit with the cardiologist the next day. He suggested a heart monitor and scheduling an echo. The heart monitor was mailed to me. I started wearing it on 2/4/21 (3 days ago). I am supposed to wear it for 7 days and then mail it back. My echo is scheduled for 3/4/21. Again, I have had no previous cardiac history. I am an active, healthy 38 y/o F.   These symptoms (racing heart (HR in the 110-120s), sweating palms/soles, tingling/numbness in the feet/arms, warm flushes over my chest, nausea, and a few loose stools) have continued to last for another 8 days and are debilitating. I have not been able to work.   On day 7 of these symptoms, I called my PCP?s emergency line. They suggested calling the cardiologist to see if they would consider prescribing a beta blocker for symptomatic relief. I called the cardiologist last night. They prescribed Metoprolol. I haven?t taken it yet. It?s officially day 8. I thought I was in the clear and had not had symptoms since last night, but then just now another episode of these cardiac/dysautonomia symptoms have occurred but less intense than previously.   At this point, I have had had 10 days of symptoms post Moderna vaccine #2 but 8 of those days are specifally the cardiac/dysautonomia symptoms. Although a little better, these symptoms have NOT resolved and continue.  I realize I am probably an outlier in terms of how I have reacted to this vaccine. I would love a call back to know if other people have had a similar experience, so I can understand if this is ?normal.? I understand 7% of patients in the Moderna vaccine trial had ?symptoms? lasting longer than 7 days. Were they symptoms similar to mine? Will this go away completely? Any help is appreciated.   Of note, I did develop a nice rash below my injection site on Moderna shot #1. Does that mean I?m more ?reactogenic? and would potentially have a harder time with shot #2? Does size matter in how you will react? Moderna is 100 mcg (instead of Pfizer?s 30 mcg) I am petite (5?2? and am now 106 lbs since I?ve lost weight).