Sex: U
Vaccine: TYP
Symptoms: Abdominal pain, Arthralgia, Diarrhoea, Influenza like illness, Joint stiffness
Clinical narrative: FEELING LIKE FLU; DIARRHOEA; ABDOMINAL PAIN; JOINT STIFFNESS; JOINT SWELLING; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES; PAIN; PAIN IN JOINT; This spontaneous case report was extracted through VAERS database (782509-1) on 15-Feb-19. The case was reported by a consumer via health authority. The report described a 50-year-old consumer who had abdominal pain, pain in joint, diarrhoea, feeling like flu, joint stiffness, joint swelling, pain, and loss of personal independence in daily activities following the intake of oral Vivotif (one dose every other day) (lot number: 3003214) for a vacation.  The patient had a history of GERD (Gastroesophageal reflux disease).  The consumer's concomitant medications included Gas X (simethicone), supplements included calcium and Ocuvite (lactose monohydrate, gelatin, crospovidone, magnesium stearate, titanium dioxide, and silicon dioxide).  It was reported that the consumer took the first dose of Vivotif on 10-Aug-2018. On 17-Aug-2018, the consumer developed abdominal pain followed by diarrhea. The consumer finished the treatment as prescribed. However, the following week, the consumer experienced terrible aching, swelling and stiff pain in hand's joints, which the consumer had never experienced before. By 16-Sep-2018, before the vacation began, the aching had spread all over the body joints which giving a feeling of flu but it was not a flu. The consumer contacted to doctor because while walking the consumer experience extreme pain. The consumer was not able to run or do weight lifting. The consumer took Advil to manage the ache/ pain and stiffness. Then the consumer stopped the Advil since it did not alleviate the pain/ ache and the stiffness. The consumer was not able to do physical activities. The consumer had to move very slowly and it ached a lot while walking up and down the stairs or whenever joint movements were required, even putting clothes on and off. The consumer had this problem throughout the day. The consumer was a non-smoker, not pregnant, and did not consume alcohol or drugs.  The action taken with Vivotif with respect to the events abdominal pain, pain in joint, diarrhoea, feeling like flu, joint stiffness, joint swelling, pain, and loss of personal independence in daily activities was not applicable.  The clinical outcome of the events abdominal pain, pain in joint, diarrhoea, feeling like flu, joint stiffness, joint swelling, pain, and loss of personal independence in daily activities was unknown.  Company's Comment: In this case, it was reported that the consumer had abdominal pain, pain in joint, diarrhoea, feeling like flu, joint stiffness, joint swelling, pain, and loss of personal independence in daily activities after intake of Vivotif. There seems to be a temporal association between the intake of the vaccine and the events. Hence, the causality of the events with Vivotif is assessed as possible. . However, there is limited information regarding dietary history, medical history and course of events in this consumer precludes the further assessment of the case.; Sender's Comments: Company's Comment: In this case, it was reported that the consumer had abdominal pain, pain in joint, diarrhoea, feeling like flu, joint stiffness, joint swelling, pain, and loss of personal independence in daily activities after intake of Vivotif. There seems to be a temporal association between the intake of the vaccine and the events. Hence, the causality of the events with Vivotif is assessed as possible. . However, there is limited information regarding dietary history, medical history and course of events in this consumer precludes the further assessment of the case.