Age: 81.0
Sex: F
Vaccine: COVID19
Symptoms: Joint stiffness, Musculoskeletal stiffness, Myalgia
Clinical narrative: blood pressure went up to 187 over 122; Sick; So stiff,neck is stiff, muscle stiff , bone stiff; Joints are stiff; Every joint in my body hurts; muscle pain; Headache; This spontaneous case was reported by a consumer and describes the occurrence of HYPERTENSION (blood pressure went up to 187 over 122) in an 81-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 015E21A, 001A21A and 026A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No medical history was provided by the reporter.  Concomitant products included ATENOLOL (TENORMIN) for an unknown indication.   On 26-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 17-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In November 2021, the patient experienced HYPERTENSION (blood pressure went up to 187 over 122) (seriousness criterion medically significant), ILLNESS (Sick), MUSCULOSKELETAL STIFFNESS (So stiff,neck is stiff, muscle stiff , bone stiff), JOINT STIFFNESS (Joints are stiff), ARTHRALGIA (Every joint in my body hurts), MYALGIA (muscle pain) and HEADACHE (Headache). The patient was treated with ATENOLOL for Hypertension, at a dose of 25 milligram. At the time of the report, HYPERTENSION (blood pressure went up to 187 over 122), ILLNESS (Sick), MUSCULOSKELETAL STIFFNESS (So stiff,neck is stiff, muscle stiff , bone stiff), JOINT STIFFNESS (Joints are stiff), ARTHRALGIA (Every joint in my body hurts), MYALGIA (muscle pain) and HEADACHE (Headache) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: 187/122 (High) high.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered HYPERTENSION (blood pressure went up to 187 over 122), ILLNESS (Sick), MUSCULOSKELETAL STIFFNESS (So stiff,neck is stiff, muscle stiff , bone stiff), JOINT STIFFNESS (Joints are stiff), ARTHRALGIA (Every joint in my body hurts), MYALGIA (muscle pain) and HEADACHE (Headache) to be possibly related.    Patient was using a heating pad.  Company Comment : This spontaneous case concerns an 81-year-old, female patient with no medical history reported, who experienced the unexpected, serious event of hypertension (BP 187/122) and other associated unexpected and expected, non-serious events. The events occurred on an unspecified date in Nov2021 following administration of the booster dose of the Moderna mRNA-1273. The patient took an extra dose of Atenolol 25 mg because of the high blood pressure. The outcomes of the events were unknown at the time of the report. The rechallenge was not applicable as no additional dosing will be given. The benefit-risk relationship of the Moderna mRNA-1273 is not affected by this report. Further information has been requested.   This case was linked to MOD-2021-069603 (Patient Link).; Sender's Comments: This spontaneous case concerns an 81-year-old, female patient with no medical history reported, who experienced the unexpected, serious event of hypertension (BP 187/122) and other associated unexpected and expected, non-serious events. The events occurred on an unspecified date in Nov2021 following administration of the booster dose of the Moderna mRNA-1273. The patient took an extra dose of Atenolol 25 mg because of the high blood pressure. The outcomes of the events were unknown at the time of the report. The rechallenge was not applicable as no additional dosing will be given. The benefit-risk relationship of the Moderna mRNA-1273 is not affected by this report. Further information has been requested.