Age: 5.0
Sex: M
Vaccine: HEP, DTAP, IPV, MMR, HIBV, MMR
Symptoms: Pyrexia, Speech disorder, Speech disorder developmental, Staring
Clinical narrative: Initial report received from another manufacture on 9/27/06, report number WAES0502UDA01403. Information had been received by this reporter secondary to a case in litigation. Follow up information was received by the manufacturer from a health care professional via medical records, and the source was reported as confidential. A four year old male pt, with a history of anoxia at birth and a hospitalization at 20 months of age after he was found with nifedipine in his mouth, had received a fourth dose, reported oral administration (not recommended route of administration) of Ipol, lot number 0758F, a fifth dose, right arm injection of Tripedia lot number 7H81507, a second dose, right arm injection of MMR II lot number 617368/0041D on 5/13/1997, It was reported that, at an unspecified time, the pt had experienced toxic mercury exposure secondary to mercury emissions from power plants, the mercury in thimerisol laden products and via the food chain. Per the report, minor male suffered serious and permanent neurological damage with associated learning disabilities, disorders and impairments. Per medical records that had receptive and expressive language skills at the 18-23 month level. Articulation was also delayed. The pt was diagnosed with language delay and treated with therapy sessions over the course of 1999 with focus on phonological awareness skills, grapheme/sound relationships, articulation and word retrieval. He was again given language delay therapy in June and July of 2000. The pt was evaluated (date not reported) to determine cognitive strengths and weaknesses and to plan for his educational needs. The summary was that the pt had borderline intelligence whose speech and language delays had evolved to become deficits of social and written language as well as academic delays despite his mastery of isolated facts. It was noted that the pts educational disability existed on the autism continuum as a pervasive developmental disorder. The pt had a speech and language assessment on 5/8/01, 5/14/01 and 5/21/01. The impression was receptive language skills within the average range for his chronological age. He was able to comprehend small units of information well, but, when he was required to process more lengthy information, he was less successful. He had subtle attention issues particularly in group settings and weak memory skills. He demonstrated expressive delays in pragmatic language, oral formulation and expressive grammar. A mild articulation disorder was present. Psychological evaluation on 9/21/01 and 9/28/01 indicated that the pts performance showed overall variability but was not consistent with any particular intellectual cognitive disorder. There were signs of possible neurological involvement such as slow processing speed and occasional reports of staring into space and motor clumsiness, although an assessment of his gross motor skills identified no apparent problems which would have required the provision of remedial services in that area. It was noted that the pt manifested some of the features of autism, although he did not meet all the criteria for the disorder. The pt did meet all of the criteria for pervasive developmental disorder. The reporter considered this even to be an important medical event (OMIC). Pervasive developmental disorder was considered to be disabling. At the time of this report, the pt had not recovered.