Age: 71.0
Sex: F
Vaccine: COVID19
Symptoms: Appendicitis, Blood pressure measurement, Blood test, Computerised tomogram, White blood cell count
Clinical narrative: Acute appendicitis; This spontaneous case was reported by a consumer and describes the occurrence of APPENDICITIS (Acute appendicitis) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 039D211A, 011A21A and 010M20A) for COVID-19 vaccination.     The patient's past medical history included Thyroid disorder.   On 16-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 16-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 23-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 11-Nov-2021, the patient experienced APPENDICITIS (Acute appendicitis) (seriousness criteria hospitalization and medically significant). The patient was hospitalized from 11-Nov-2021 to 12-Nov-2021 due to APPENDICITIS. The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) at an unspecified dose and frequency and Surgery (Appendectomy on 11-NOV-2021) for Appendicitis. At the time of the report, APPENDICITIS (Acute appendicitis) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 11-Nov-2021, Blood pressure measurement: elevated (High) Elevated. On 11-Nov-2021, Blood test: abnormal (abnormal) abnormal. On 11-Nov-2021, Computerised tomogram: abnormal (abnormal) Appendix was inflamed.. On 11-Nov-2021, White blood cell count: high (High) 30,000. On an unknown date, Blood test: normal (normal) normal.         Company comment: This is a spontaneous case concerning a 71-year-old female patient with no reported medical history, who experienced the serious unexpected event acute appendicitis that lead to hospitalization and surgery: appendicectomy. The event occurred approximately 17 days after the third dose of mRNA-1273.  The benefit-risk relationship of mRNA-1273 is not affected by this report.  Concomitant medication include thyroid replacement medication for her mal function thyroid. Symptoms: started on 09Nov2021. She had gastrointestinal pain on the abdominal area, nauseated, could not keep anything down, was throwing up, sick, tired and weak. 10Nov2021 pain worsened and she called her doctor. She was informed to monitor for a while. On 11Nov2021 she was admitted to the emergency department. Her test for white cells were 30 000 (normal upper limit:10 000). Blood pressure was elevated. When the doctor saw her blood, they suspected heart failure. Blood values were abnormal. CT Scan showed that the appendix was inflamed. On the same day at 11Nov2021, patient had surgery in the afternoon. She spend one night in the hospital and was discharged on the 12Nov2021.; Sender's Comments: Company comment: This is a spontaneous case concerning a 71-year-old female patient with no reported medical history, who experienced the serious unexpected event acute appendicitis that lead to hospitalization and surgery: appendicectomy. The event occurred approximately 17 days after the third dose of mRNA-1273.  The benefit-risk relationship of mRNA-1273 is not affected by this report.