Age: 68.0
Sex: F
Vaccine: COVID19-2
Symptoms: Arthralgia, Arthritis, Inflammation, Joint swelling, Pain in extremity
Clinical narrative: over the next few months i had severe inflammation in both hands and then other joints on my rt side became swollen and inflamed; over the next few months i had severe inflammation in both hands; a few days later my rt wrist became swollen and painful; i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand; i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand; This spontaneous case was reported by a patient and describes the occurrence of ARTHRITIS (over the next few months i had severe inflammation in both hands and then other joints on my rt side became swollen and inflamed), INFLAMMATION (over the next few months i had severe inflammation in both hands), JOINT SWELLING (a few days later my rt wrist became swollen and painful), PAIN IN EXTREMITY (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand) and ARTHRALGIA (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand) in a 68-year-old female patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. AS7147B) for COVID-19 prophylaxis.     No Medical History information was reported.    On 23-Sep-2022, the patient received dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Intramuscular use) 1 dosage form. In September 2022, the patient experienced PAIN IN EXTREMITY (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand). On 24-Sep-2022,  after starting mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)), the patient experienced ARTHRALGIA (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand). On an unknown date, the patient experienced ARTHRITIS (over the next few months i had severe inflammation in both hands and then other joints on my rt side became swollen and inflamed), INFLAMMATION (over the next few months i had severe inflammation in both hands) and JOINT SWELLING (a few days later my rt wrist became swollen and painful). On 25-Sep-2022, ARTHRALGIA (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand) had resolved. At the time of the report, ARTHRITIS (over the next few months i had severe inflammation in both hands and then other joints on my rt side became swollen and inflamed), INFLAMMATION (over the next few months i had severe inflammation in both hands), JOINT SWELLING (a few days later my rt wrist became swollen and painful) and PAIN IN EXTREMITY (i had severe pain the following day in most of my joints this resolved in two days but lingered in my rt hand) had not resolved.        For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Intramuscular use), the reporter did not provide any causality assessments.   No concomitant medications were reported.  It was reported that patient had severe pain the following day in most of her joints this resolved in two days but lingered in her right hand. A few days later her right wrist became swollen and painful. over the next few months, she had severe inflammation in both hands and then other joints on her right side became swollen and inflamed.   Reported that her PC did not believe that it was caused by the vaccine. Patient was not able to see a rheumatologist until April 2023. By then the inflammation was rampant. Patient know the vaccine caused this and she was fine before she had the vaccine and after the vaccine this all began. Patient was still in pain from this at the time of reporting.  No treatment medications were reported.  Company comment:  This spontaneous case concerns a 68  year  old female patient, with no medical history reported, who received a dose of Moderna Bivalent (Original and Omicron BA.4/BA.5) COVID -19 Vaccine (Elasomeran, Davesomeran) and experienced the unexpected, non  serious AESI arthritis. Latency cannot be properly assessed since exact onset date was not provided. The report stated that the patient experienced pain in most of her joints the day after vaccination, which was recovered except in her right hand. A few days later her right wrist was swollen and painful. The following months she had inflammation in both hands and other joints. She consulted a rheumatologist; however, no further clinical information was provided. The outcome of the event was not recovered. The benefit-risk relationship of Moderna Bivalent (Original and Omicron BA.4/BA.5) COVID -19 Vaccine is not affected by this report.