Age: 24.0
Sex: M
Vaccine: COVID19, COVID19, COVID19
Symptoms: Hypobarism, Hypovolaemia, Injection site pain, Laboratory test, Magnetic resonance imaging heart
Clinical narrative: Adrenal Insufficiency; Hypovolemia; racing heart; Pre-load insufficiency/decreased ventricular preload; CIRS; ME-CFS; ME-CFS; POT/ Postural orthostatic tachycardia syndrome; Long COVID; 25% deficient in blood volume; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 24-year-old male patient received BNT162b2 (BNT162B2), on 18Dec2021 as dose 3 (booster), single (Lot number: FD7218) at the age of 24 years for covid-19 immunisation. The patient's relevant medical history included: "Asthma" (unspecified if ongoing); "pelvic floor dysfunction" (unspecified if ongoing); "Known allergies: Dairy" (unspecified if ongoing); "Known allergies: eggs" (unspecified if ongoing); "Known allergies: nuts" (unspecified if ongoing). Concomitant medication(s) included: DULERA; GAVILYTE C. Vaccination history included: BNT162b2 (Dose 1, Single, lot number: ER8737), administration date: 02Apr2021, for COVID-19 immunisation; BNT162b2 (Dose 2, Single, lot number: EN6207), administration date: 21Apr2021, for COVID-19 immunisation. The following information was reported: VOLUME BLOOD DECREASED (disability) with onset 09Feb2022, outcome "not recovered", described as "25% deficient in blood volume"; ADRENAL INSUFFICIENCY (disability, medically significant) with onset 09Feb2022, outcome "not recovered"; CHRONIC INFLAMMATORY RESPONSE SYNDROME (disability, medically significant) with onset 09Feb2022, outcome "not recovered", described as "CIRS"; HYPOVOLAEMIA (disability) with onset 09Feb2022, outcome "not recovered", described as "Hypovolemia"; POST-ACUTE COVID-19 SYNDROME (disability) with onset 09Feb2022, outcome "not recovered", described as "Long COVID"; POST VIRAL FATIGUE SYNDROME (disability), CHRONIC FATIGUE SYNDROME (disability) all with onset 09Feb2022, outcome "not recovered" and all described as "ME-CFS"; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (disability) with onset 09Feb2022, outcome "not recovered", described as "POT/ Postural orthostatic tachycardia syndrome"; DECREASED VENTRICULAR PRELOAD (disability) with onset 09Feb2022, outcome "not recovered", described as "Pre-load insufficiency/decreased ventricular preload"; PALPITATIONS (disability) with onset 09Feb2022, outcome "not recovered", described as "racing heart". The events "adrenal insufficiency", "hypovolemia", "racing heart", "pre-load insufficiency/decreased ventricular preload", "cirs", "me-cfs", "pot/ postural orthostatic tachycardia syndrome", "long covid" and "25% deficient in blood volume" required emergency room visit. The patient underwent the following laboratory tests and procedures: Volume blood: (09Feb2022) 25 %, notes: deficient. Therapeutic measures were not taken as a result of adrenal insufficiency, palpitations, chronic inflammatory response syndrome, post viral fatigue syndrome, chronic fatigue syndrome, postural orthostatic tachycardia syndrome, post-acute covid-19 syndrome. Therapeutic measures were taken as a result of hypovolaemia, decreased ventricular preload, volume blood decreased. Clinical course: No other vaccine in four weeks. Adverse event: First event was not until 09Feb2022. He had a racing heart while weight lifting and went to ER. However, though he was a healthy, young college graduate at the time, his health had deteriorated to the point that he was in a wheelchair and taking 3-4 liters of IV fluids a day. His diagnoses had included: Hypovolemia (25% deficient in blood volume) Pre-load insufficiency Adrenal Insufficiency POT ME-CFS CIRS Long COVID Likely vaccine injury. Patient dis not receive any other vaccines within 4 weeks prior to the COVID vaccine. Adverse event resulted in: Emergency room/department or urgent care.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300238302 Same patient/product, different dose/events (LOE);