Age: 76.0
Sex: M
Vaccine: VARZOS
Symptoms: Pain in extremity, Weight bearing difficulty, X-ray limb abnormal
Clinical narrative: This case was reported by a consumer via call center representative and described the occurrence of nasal stuffiness in a 76-year-old male patient who received SHINGRIX for prophylaxis. Previously administered products included ZOSTAVAX. On 30th November 2018, the patient received the 2nd dose of SHINGRIX. On 30th November 2018, immediately after receiving SHINGRIX, the patient experienced nasal stuffiness. On 1st December 2018, the patient experienced injection site pain and injected limb mobility decreased. On 2nd December 2018, the patient experienced muscle swelling and muscular back pain. On 9th December 2018, the patient experienced calcium deposits. In December 2018, the patient experienced shoulder pain, pain in arm and mobility decreased. On 26th December 2018, the patient experienced weight bearing difficulty, walking difficulty and knee pain. On 30th December 2018, the patient experienced muscle tightness. On an unknown date, the patient experienced difficulty sleeping. The patient was treated with sodium bicarbonate + sodium chloride (Neti Pot), nyquil (nos) (Nyquil), naproxen, tramadol, baclofen, prednisone, melatonin and bengay (nos) (Bengay). In December 2018, the outcome of the injection site pain, shoulder pain, pain in arm and mobility decreased were recovered/resolved. On an unknown date, the outcome of the nasal stuffiness, injected limb mobility decreased, weight bearing difficulty, walking difficulty, muscle tightness, difficulty sleeping, muscle swelling, muscular back pain, knee pain and calcium deposits were unknown. It was unknown if the reporter considered the nasal stuffiness, injection site pain, injected limb mobility decreased, weight bearing difficulty, walking difficulty, muscle tightness, difficulty sleeping, muscle swelling, muscular back pain, knee pain, shoulder pain, pain in arm, mobility decreased and calcium deposits to be related to SHINGRIX.  Additional details were provided as follows: The reporter was the patient's wife. The patient received the vaccine on left arm and immediately after receiving vaccine, the patient felt like his head was stuffy. The patient went home and used Netti pot and took Nyquil incase he was getting cold. The next day the patient's left shoulder was semi paralyzed, meaning the patient could not able to raise his arm. On 2nd December 2018, the patient went to urgent care and was prescribed Naproxyn and Tramadol for pain. On 2nd December 2018, 2 days after receiving SHINGRIX, the reporter reported that the patient's lower left back muscle was swollen and painful. The reporter reported that the pain was resolved. Few days later there was a pain in the patient's right shoulder and arm and he could not able to raise his arm. On 9th December 2018, the patient went back to the urgent care and X-rays were taken. The X-rays were negative except for calcium build up with age. The patient was given Naproxyn and Baclofen. The reporter reported that the area was resolved. On 26th December 2018, 26 days after receiving SHINGRIX, the pain went to the patient's left knee. The patient was not able to support his weight or walk. On 29th December 2018, the patient saw his internist. On 30th December 2018, 30 days after receiving SHINGRIX, the patient experienced chest tightness, which reporter noted was muscle. The reporter placed a phone call back to the internist, who prescribed Prednisone for the chest muscle tightness. The reporter reported that she had also used Bengay on the patient's chest muscles. The reporter also noted that the patient was not able to sleep for long periods, he would sleep for couple of hours, awaken and then was able to return to sleep for couple more hours. The patient had been taken Melatonin for this issue to help the last two nights.  The reporter noted the patient was out of work for quite a while and had finally returned.