Age: 60.0
Sex: F
Vaccine: COVID19
Symptoms: Colour vision tests, Magnetic resonance imaging, Ophthalmological examination, Optic ischaemic neuropathy
Clinical narrative: she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy; This spontaneous case was reported by a consumer and describes the occurrence of OPTIC ISCHAEMIC NEUROPATHY (she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concomitant products included CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) and VITAMINS NOS for an unknown indication.    On 15-Dec-2021, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced OPTIC ISCHAEMIC NEUROPATHY (she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy) (seriousness criterion medically significant). At the time of the report, OPTIC ISCHAEMIC NEUROPATHY (she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 27-Dec-2021, Magnetic resonance imaging: normal (normal) She was sent for Stat MRI which came back ok. On an unknown date, Colour vision tests: abnormal (abnormal) Part of the diagnosis was conducted with a color test book that she had to pick out a number in the colors. At this time she says her vision in her left eye looks like a grey slash in the middle of her eye. On an unknown date, Ophthalmological examination: low (Low) She does not have complete vision loss. Her right eye is 20/20, left eye is 20/30.         On 23-Dec-2021, she had flashing in her eyes and an optic migraine, on 25-Dec-2021, she was having a block in her field of vision in her left eye. She says she would cover her right eye with her hand, and she could not see the left side of her face. On 27-Dec-2021, she went to her ophthalmologist and was told she had swelling behind her optic nerve and was sent for a stat MRI. The MRI came back ok, and she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy that there was no treatment or cure for because of the damage to the nerve. She was told she could have possibly improved in vision, but it was unknown. She does not have complete vision loss. Her right eye was 20/20, left eye is 20/30. Part of the diagnosis was conducted with a color test book that she had to pick out a number in the colors. At this time, her vision in her left eye looks like a grey slash in the middle of her eye. She took over the counter Zyrtec and vitamins. She consents for safety to contact.  company comment:This case concerns a  60-year-old female patient with unknown medical history, who experienced serious unexpected OPTIC ISCHAEMIC NEUROPATHY following administration of mRNA-1273. It was reported that the initial symptoms occurred eight day after the third dose of mRNA-1273; the patient developed optic migraine and  flashing in her eyes. On the following days she developed  block in her field of vision/she would cover her right eye with her hand and she could not see the left side of her face, swelling behind her optic nerve; she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy. Diagnostic results included: inconclusive MRI and ophthalmic examination: right eye 20/20, left eye 20/30, and Colour vision tests: abnormal. Treatment details and outcome was unknown. The rechallenge was not applicable as no additional dosing will be given. The reporter did not provide causality assessment. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This case concerns a  60-year-old female patient with unknown medical history, who experienced serious unexpected OPTIC ISCHAEMIC NEUROPATHY following administration of mRNA-1273. It was reported that the initial symptoms occurred eight day after the third dose of mRNA-1273; the patient developed optic migraine and  flashing in her eyes. On the following days she developed  block in her field of vision/she would cover her right eye with her hand and she could not see the left side of her face, swelling behind her optic nerve; she went to see a specialist that diagnosed her with non arteric ischemic optic neuropathy. Diagnostic results included: inconclusive MRI and ophthalmic examination: right eye 20/20, left eye 20/30, and Colour vision tests: abnormal. Treatment details and outcome was unknown. The rechallenge was not applicable as no additional dosing will be given. The reporter did not provide causality assessment. The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.