Age: 61.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Asthenia, B-cell small lymphocytic lymphoma, Biopsy lymph gland abnormal, Chest discomfort, Chronic lymphocytic leukaemia
Clinical narrative: Diagnosed with non-Hodgkin's lymphoma; Night sweats; Unexplained weight loss; Excruciating pain in left arm from lymph node; Fatigue; This spontaneous case was reported by a consumer and describes the occurrence of NON-HODGKIN'S LYMPHOMA (Diagnosed with non-Hodgkin's lymphoma) in a 61-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 014C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 04-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 07-Jun-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 10-Jun-2021, the patient experienced NIGHT SWEATS (Night sweats), WEIGHT DECREASED (Unexplained weight loss), LYMPH NODE PAIN (Excruciating pain in left arm from lymph node) and FATIGUE (Fatigue). On 07-Sep-2021, the patient experienced NON-HODGKIN'S LYMPHOMA (Diagnosed with non-Hodgkin's lymphoma) (seriousness criterion medically significant). At the time of the report, NON-HODGKIN'S LYMPHOMA (Diagnosed with non-Hodgkin's lymphoma), NIGHT SWEATS (Night sweats), WEIGHT DECREASED (Unexplained weight loss), LYMPH NODE PAIN (Excruciating pain in left arm from lymph node) and FATIGUE (Fatigue) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 15-Jun-2021, White blood cell count: 32000 (abnormal) White blood cells: 32000.         No concomitant medication were reported.  No treatment information was reported.  Company comment- This case concerns a  61-year-old, male patient with no relevant medical history, who experienced the unexpected events of Non Hodgkin's lymphoma, night sweats, weight decreased and lymph node pain and expected event of Fatigue. The events of night sweats, weight decreased, fatigue and lymph node pain occurred approximately three days after the second dose of Moderna COVID-19 Vaccine, while diagnosis of Non Hodgkin's lymphoma was made three months after second dose. The benefit-risk relationship of Moderna COVID-19 Vaccine in not affected by this report.   This case was linked to MOD-2021-245684 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 07-Sep-2021: Followed up received on 7-SEP-2021 that contains updated event as Non-Hodgkin's lymphoma. Case upgraded to serious.; Sender's Comments: This case concerns a  61-year-old, male patient with no relevant medical history, who experienced the unexpected events of Non Hodgkin's lymphoma, night sweats, weight decreased and lymph node pain and expected event of Fatigue. The events of night sweats, weight decreased, fatigue and lymph node pain occurred approximately three days after the second dose of Moderna COVID-19 Vaccine, while diagnosis of Non Hodgkin's lymphoma was made three months after second dose. The benefit-risk relationship of Moderna COVID-19 Vaccine in not affected by this report.