chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 14.0
Sex: F
Vaccine: HPV4
Symptoms: Ovarian cyst, Pain, Pancreatitis, Pneumonia, Ultrasound scan abnormal
Clinical narrative: nose bleeds, headaches sudden onset after first shot continued after second and third shot third shot 6/9/08 fatigue, end of July received meningits vaccine sept started pain, cyst on ovaries,then nausea,vomiting,pancreatitis,gastrointestinal disorders,dizziness,pnenmonia,lactating,hypersensitivity,8 weeks in hospital still sick  1/27/09 Link with 338052.  2/2/09 Received hospital & clinic medical records for 9/18-12/10/2008. FINAL DX: Pancreatitis Records reveal patient seen in ER 9/18 for RLQ flank/abdominal pain with nausea, fever & cough x 2 days.  Improved w/meds & d/c to home.  Returned w/severe pain.   Hospital admit 9/20-9/22/2008.  FINAL DX: right flank pain, resolving; pneumonia, resolving.  Records reveal RLQ flank/abdominal pain improved.  d/c to home on continued oral antibiotics for pneumonia & w/GYN f/u.  OB/GYN records of  10/7 & 10/8 & Operative report of 9/24/2008. FINAL DX: RLQ pain w/bilateral ovarian cysts Patient had laparoscopic aspiration of ovarian cysts as same day surgery.  Had continued post op RLQ abdominal pain.  US was WNL.  referred to PCP for additional GI w/u.  Returned to ER 10/23/2008 W/persistent RLQ pain.  Labs all WNL & d/c to home.  Returned to ER 12/10/2008 w/nausea, vomiting, dry heaves x 1 day, diarrhea x 2 weeks.  Had recently been d/c from higher level of care w/dx pancreatitis & was on TPN.  Found to have ileus.  Tx w/meds & d/c to home.  2/17/09 Received hospital medical records of 11/21-12/3/2008. FINAL DX:allodynia w/abdominal wall pain improving; hyperlipasemia, etiology uncertain; galactorrhea & hyperprolactinemia secondary to Lexapro; marked disability in association w/chronic pain; intermittent, frequent belching/retching related to disability & chronic pain. Records reveal patient experienced RLQ pain.  Had been transferred from outlying hospital where she had been admitted 10/15/08 & extensive medical record review of that hospitalization included.  Endocrine, pain mgt, psych consult done & meds adjusted.  Tx w/TPN.  Improved & d/c to home w/continued TPN, pain meds, PT, psych counseling & serial labs.
Age: 14.0
Sex: F
Vaccine: HPV4
Symptoms: Vomiting, X-ray abnormal
Clinical narrative: nose bleeds, headaches sudden onset after first shot continued after second and third shot third shot 6/9/08 fatigue, end of July received meningits vaccine sept started pain, cyst on ovaries,then nausea,vomiting,pancreatitis,gastrointestinal disorders,dizziness,pnenmonia,lactating,hypersensitivity,8 weeks in hospital still sick  1/27/09 Link with 338052.  2/2/09 Received hospital & clinic medical records for 9/18-12/10/2008. FINAL DX: Pancreatitis Records reveal patient seen in ER 9/18 for RLQ flank/abdominal pain with nausea, fever & cough x 2 days.  Improved w/meds & d/c to home.  Returned w/severe pain.   Hospital admit 9/20-9/22/2008.  FINAL DX: right flank pain, resolving; pneumonia, resolving.  Records reveal RLQ flank/abdominal pain improved.  d/c to home on continued oral antibiotics for pneumonia & w/GYN f/u.  OB/GYN records of  10/7 & 10/8 & Operative report of 9/24/2008. FINAL DX: RLQ pain w/bilateral ovarian cysts Patient had laparoscopic aspiration of ovarian cysts as same day surgery.  Had continued post op RLQ abdominal pain.  US was WNL.  referred to PCP for additional GI w/u.  Returned to ER 10/23/2008 W/persistent RLQ pain.  Labs all WNL & d/c to home.  Returned to ER 12/10/2008 w/nausea, vomiting, dry heaves x 1 day, diarrhea x 2 weeks.  Had recently been d/c from higher level of care w/dx pancreatitis & was on TPN.  Found to have ileus.  Tx w/meds & d/c to home.  2/17/09 Received hospital medical records of 11/21-12/3/2008. FINAL DX:allodynia w/abdominal wall pain improving; hyperlipasemia, etiology uncertain; galactorrhea & hyperprolactinemia secondary to Lexapro; marked disability in association w/chronic pain; intermittent, frequent belching/retching related to disability & chronic pain. Records reveal patient experienced RLQ pain.  Had been transferred from outlying hospital where she had been admitted 10/15/08 & extensive medical record review of that hospitalization included.  Endocrine, pain mgt, psych consult done & meds adjusted.  Tx w/TPN.  Improved & d/c to home w/continued TPN, pain meds, PT, psych counseling & serial labs.
Age: 23.0
Sex: F
Vaccine: HPV4
Symptoms: Cellulitis, Computerised tomogram normal, Fasciitis, Injection site erythema, Injection site pain
Clinical narrative: Patient received vaccine and initially had soreness at the injection site for about 2 weeks. On 11/29 she noticed redness and warmth in addition to pain in the area. This initally improved without any treatment. Symptoms began to worsen again (redness, pain, warmth in the deltoid area of the arm) and she was seen at an urgent care facility on 12/9 and was given Keflex 250mg TID. Symptoms continued to worsen. She presented to the Emergency Department on 12/13/08 and was given a 1 gram dose of Vancomycin IV and was ultimately discharged home on Keflex 500mg QID and Bactrim DS - 1 tab BID. Patient reports initial improvement after the antibiotic change but then symptoms again worsened and she returned to the ED on 12/16/08 and was admitted to the hospital for IV antibiotics with worsening erythema and pain. She is currently on vancomycin IV and Clindamycin IV was added today because symptoms are not significantly improving. There is no abcess associated with the cellululitis. Patient is still in the hospital- anticipated discharge date unknown. 2/2/09-records received for DOS 12/16-12/19/08 DC DX:Myositis/fascitis.Presented to ER with 6 week history of LUE cellulitis at which time received 3rd gardasil  injection in left arm. After injection noticed army sore 1 week later with red ring around injeciton site and treated with oral antibiotics. LUE pain worsing and redness spreading, decreased ROM, fever feeeling lethergic/fatigued. Presented with chills decreased oral intake.
Age: 23.0
Sex: F
Vaccine: HPV4
Symptoms: Injection site warmth, Laboratory test normal, Myositis, Nuclear magnetic resonance imaging abnormal, White blood cell count increased
Clinical narrative: Patient received vaccine and initially had soreness at the injection site for about 2 weeks. On 11/29 she noticed redness and warmth in addition to pain in the area. This initally improved without any treatment. Symptoms began to worsen again (redness, pain, warmth in the deltoid area of the arm) and she was seen at an urgent care facility on 12/9 and was given Keflex 250mg TID. Symptoms continued to worsen. She presented to the Emergency Department on 12/13/08 and was given a 1 gram dose of Vancomycin IV and was ultimately discharged home on Keflex 500mg QID and Bactrim DS - 1 tab BID. Patient reports initial improvement after the antibiotic change but then symptoms again worsened and she returned to the ED on 12/16/08 and was admitted to the hospital for IV antibiotics with worsening erythema and pain. She is currently on vancomycin IV and Clindamycin IV was added today because symptoms are not significantly improving. There is no abcess associated with the cellululitis. Patient is still in the hospital- anticipated discharge date unknown. 2/2/09-records received for DOS 12/16-12/19/08 DC DX:Myositis/fascitis.Presented to ER with 6 week history of LUE cellulitis at which time received 3rd gardasil  injection in left arm. After injection noticed army sore 1 week later with red ring around injeciton site and treated with oral antibiotics. LUE pain worsing and redness spreading, decreased ROM, fever feeeling lethergic/fatigued. Presented with chills decreased oral intake.
Age: 21.0
Sex: M
Vaccine: FLU3, HEPA, TDAP, YF
Symptoms: Dyspnoea, Pruritus, Urticaria
Clinical narrative: Patient's father called 2 hours after patient received Hepatitis A, Tdap (Adacel), Influenza, and Yellow Fever stating patient was experiencing itchiness, hives and difficulty breathing. Patient was instructed that if available, to take Benadryl and to go immediately to the Emergency Room. On follow up phone call 12/17/2008, patient stated that the onset of symptoms was 45 minutes after receiving vaccines. Patient stated that when he left the hospital around 3 pm on 12/16/2008, that he felt perfectly normal and that he continues to feel healthy. Patient stated he received IV fluids, he thinks Benadyrl and Epinephrine. The ER gave him prescriptions for Prednisone and Diphenhydramine hydrochloride.
Age: 15.0
Sex: F
Vaccine: VARCEL
Symptoms: Erythema, Swelling
Clinical narrative: red and swollen, treatment cipro
Age: 80.0
Sex: M
Vaccine: FLU3
Symptoms: Herpes virus infection
Clinical narrative: Patient experienced a herpes outbreak after flu shot. Patient took acyclovir and "felt better". ACYCLOVIR 800MG TAB TAKE ONE-HALF TABLET BY MOUTH THREE TIMES A DAY FOR 10 DAYS.
Age: 76.0
Sex: F
Vaccine: FLU3
Symptoms: Abasia, Asthenia, Blood product transfusion, Gait disturbance, Guillain-Barre syndrome
Clinical narrative: This case was reported by a consumer and described the occurrence of Guillain-Barre in a 76-year-old female subject who was vaccinated with FLULAVAL (GlaxoSmithKline). A physician or other healthcare professional has not verified this report. Concurrent medical conditions included gas and high cholesterol. Concurrent medications included PREVACID and LIPITOR. On 12 November 2008, the subject received unspecified dose of FLULAVAL (intramuscular, unknown). On 26 November 2008, 14 days after vaccination with FLULAVAL, the subject experienced feeling weak, could not walk. On 01 December 2008, the subject was diagnosed with Guillain-Barre. At an unknown time after vaccination with FLULAVAL the subject had numbness (hands and legs) and was nonresponsive. The subject was hospitalised. The subject was treated with normal immunoglobulin (IVIG). The daughter of a female subject reported that her mother received an immunization of FLULAVAL on 12 November 2008. On 28 November 2008, the subject reported feeling weak, and had difficulty walking. During the period of 26 November 2008 to 01 December 2008, the subject's symptoms had become worse. On 01 December 2008, the subject was hospitalized. A diagnosis of Guillain Barre syndrome was made. The subject received IVIG and is still unresponsive. At the time of the report, the subject remained hospitalized. At the time of reporting the events were unresolved.  2/2/09 Received hospital medical records of 12/1-1/20/2009. FINAL DX: Guillain Barre syndrome s/p IVIG & plasmapheresis; left shoulder rotator cuff tear. Records reveal patient experienced ascending LE weakness & paralysis & RUQ abdominal pain x 4-5 days.  Had similar symptoms 14 yrs prior that responded to outpatient steroids.  Neuro consult done.  Tx steroids initially then, w/IVIG w/minimal improvement then plasmapheresis x 2.5 weeks.  Initially HTN tx w/meds & diuresis.  Became hypotensive w/plasmapheresis, antiHTN meds d/c. Developed thrombocytopenis due to DVT prophylaxis & meds changed.   Developed low grade fever & ID consult done.  Tx w/IV antibiotics for possible early cellulitis.  Tx w/PT/OT & transferred to inpatient rehab & continued to be followed by neuro.   Improved & d/c to home w/continued PMR & Neuro f/u.
Age: 76.0
Sex: F
Vaccine: FLU3
Symptoms: Hypoaesthesia, Unresponsive to stimuli
Clinical narrative: This case was reported by a consumer and described the occurrence of Guillain-Barre in a 76-year-old female subject who was vaccinated with FLULAVAL (GlaxoSmithKline). A physician or other healthcare professional has not verified this report. Concurrent medical conditions included gas and high cholesterol. Concurrent medications included PREVACID and LIPITOR. On 12 November 2008, the subject received unspecified dose of FLULAVAL (intramuscular, unknown). On 26 November 2008, 14 days after vaccination with FLULAVAL, the subject experienced feeling weak, could not walk. On 01 December 2008, the subject was diagnosed with Guillain-Barre. At an unknown time after vaccination with FLULAVAL the subject had numbness (hands and legs) and was nonresponsive. The subject was hospitalised. The subject was treated with normal immunoglobulin (IVIG). The daughter of a female subject reported that her mother received an immunization of FLULAVAL on 12 November 2008. On 28 November 2008, the subject reported feeling weak, and had difficulty walking. During the period of 26 November 2008 to 01 December 2008, the subject's symptoms had become worse. On 01 December 2008, the subject was hospitalized. A diagnosis of Guillain Barre syndrome was made. The subject received IVIG and is still unresponsive. At the time of the report, the subject remained hospitalized. At the time of reporting the events were unresolved.  2/2/09 Received hospital medical records of 12/1-1/20/2009. FINAL DX: Guillain Barre syndrome s/p IVIG & plasmapheresis; left shoulder rotator cuff tear. Records reveal patient experienced ascending LE weakness & paralysis & RUQ abdominal pain x 4-5 days.  Had similar symptoms 14 yrs prior that responded to outpatient steroids.  Neuro consult done.  Tx steroids initially then, w/IVIG w/minimal improvement then plasmapheresis x 2.5 weeks.  Initially HTN tx w/meds & diuresis.  Became hypotensive w/plasmapheresis, antiHTN meds d/c. Developed thrombocytopenis due to DVT prophylaxis & meds changed.   Developed low grade fever & ID consult done.  Tx w/IV antibiotics for possible early cellulitis.  Tx w/PT/OT & transferred to inpatient rehab & continued to be followed by neuro.   Improved & d/c to home w/continued PMR & Neuro f/u.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Haematoma, Injection site erythema, Injection site pruritus, Injection site reaction, Injection site swelling
Clinical narrative: Subject reported on 12/11/08 what sounds to be a hematoma.  He described red, itchy, swollen, hot, localized reaction at injection site.  Her physician recommended BENADRYL.  1 recommended pt also take IBUPROFEN and apply ice.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site warmth
Clinical narrative: Subject reported on 12/11/08 what sounds to be a hematoma.  He described red, itchy, swollen, hot, localized reaction at injection site.  Her physician recommended BENADRYL.  1 recommended pt also take IBUPROFEN and apply ice.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Dizziness, Dyspnoea, Fatigue, Headache, Heart rate increased
Clinical narrative: 63 year old female received ZOSTAVAX 12/11/08 - reports slight headache about 4 hrs after increasedfatigue 12-24 hrs later dizzy, rapid heartbeat, shortness of breath, lightheaded about 24-36 hrs later. (L) arm swollen, localized rash, itchy (injection site)  (redness, painful) improving.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site pain, Injection site pruritus, Oedema peripheral, Rash
Clinical narrative: 63 year old female received ZOSTAVAX 12/11/08 - reports slight headache about 4 hrs after increasedfatigue 12-24 hrs later dizzy, rapid heartbeat, shortness of breath, lightheaded about 24-36 hrs later. (L) arm swollen, localized rash, itchy (injection site)  (redness, painful) improving.
Age: 1.0
Sex: M
Vaccine: FLU3, HEPA, PNC, VARCEL
Symptoms: Injection site rash
Clinical narrative: Rash at injection site s/p 9d.
Age: 51.0
Sex: F
Vaccine: FLU3, TDAP
Symptoms: Erythema, Pain, Swelling
Clinical narrative: 1) Swelling and erythema 4 cm x 3 cm of left deltoid. Pain after 5 days. Ibuprofen and ice.
Age: 46.0
Sex: F
Vaccine: TDAP
Symptoms: Cellulitis, Dermatitis allergic, Erythema, Oedema peripheral, Pain
Clinical narrative: (L) deltoid is swelling, red and itching. Allergic dermatitis vs cellulitis. (1) MEDROL dose, pain. (2) KEFLEX 500 mg.
Age: 46.0
Sex: F
Vaccine: TDAP
Symptoms: Pruritus
Clinical narrative: (L) deltoid is swelling, red and itching. Allergic dermatitis vs cellulitis. (1) MEDROL dose, pain. (2) KEFLEX 500 mg.
Age: 12.0
Sex: F
Vaccine: FLU3, HPV4, TDAP, VARCEL
Symptoms: Dizziness, Hyperhidrosis, Nausea, Pallor
Clinical narrative: Pt. had dizziness and nausea after vaccination. Had pallor and diaphoresis. Vital stable. CNS exam. WNL. Referred to ER for eval.
Age: 0.6
Sex: F
Vaccine: DTAP, FLU3, HIBV, IPV, PNC
Symptoms: Injection site erythema, Irritability, Pyrexia
Clinical narrative: redness in bilateral thigh, fever, very irritable, cranky. The next morning after being given vaccine.
Age: 7.0
Sex: M
Vaccine: FLU3
Symptoms: Pruritus, Urticaria
Clinical narrative: Started with itching, then hives on arms, legs and abdomen. Given BENADRYL.
Age: 54.0
Sex: M
Vaccine: FLU3
Symptoms: Injection site erythema, Rash erythematous, Rash pruritic, Skin plaque
Clinical narrative: Erythematous plague at injection site. Disseminated erythematous Pruritic plague (20 over trunk, upper arms). Persisted for weeks. Patient self treated with hydrocortisone 1% topical.
Age: 16.0
Sex: M
Vaccine: FLUN3
Symptoms: Urticaria
Clinical narrative: Patient administered FLUMIST vaccine 11/14/2008 via nasal route. Only vaccine given. Developed Urticaria about 3 hours later.
Sex: U
Vaccine: TDAP, VARCEL
Symptoms: Herpes zoster, Rash
Clinical narrative: Shingles rash on face and ear 10 days after vaccine. Treated initially with ABx and then with ZOVIRAX with improvement.
Age: 11.0
Sex: F
Vaccine: MNQ, TDAP
Symptoms: Grand mal convulsion, Syncope
Clinical narrative: Syncope, seizure tonic clonic type lasting about 1 minute, came to administered 02.
Age: 3.0
Sex: M
Vaccine: DTAP, FLU3, HEPA
Symptoms: Injection site erythema, Injection site pain
Clinical narrative: 7" x 6" of  erythematous, some pain, Right thigh
Age: 1.0
Sex: F
Vaccine: HBHEPB, MMRV
Symptoms: Ataxia, Nystagmus, Postictal state
Clinical narrative: Information has been received from a physician concerning a 12 month old female with iron deficiency anaemia who on 22-AUG-2007, at 14:10, was vaccinated, into the right leg, with a fourth dose of hepatitis B virus vaccine rHBsAg (yeast) (+) Hib conj vaccine (OMPC) (lot #00160"). Concomitant vaccination on 22-AUG-2007 included a first dose of MMR varicella vaccine, for the treatment of prophylaxis (MSD) (lot #655847/1386F) into the left leg. On 26-AUG-2007 the patient experienced horizontal nystagmus and was ataxic. The patient was evaluated in the emergency room 3 hours post-ictal. Subsequently, the patient recovered. It was reported that the patient had an appointment scheduled with neurology. Additional information is not expected.
Age: 26.0
Sex: F
Vaccine: FLU3, TDAP, FLU3, TDAP
Symptoms: Cough, Ocular hyperaemia
Clinical narrative: Pt. called health unit to report eyes red, cough/stopped, approximately starting one hour after vaccines administered. Instructed to report to E.R. for evaluation.
Age: 26.0
Sex: F
Vaccine: FLU3, TDAP, FLU3, TDAP
Symptoms: Cough, Ocular hyperaemia, Respiratory tract congestion
Clinical narrative: Pt. called health unit to report eyes red, cough/stopped, approximately starting one hour after vaccines administered. Instructed to report to E.R. for evaluation.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Antibody test negative, Ascites, Biopsy kidney abnormal, Bronchoscopy, Chromaturia
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Cytomegalovirus antibody negative, Diffuse alveolar damage, Dyspnoea, Generalised oedema, Glomerulonephropathy
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Histology, Nephrotic syndrome, Oedema, Pleural effusion, Purpura
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Respiratory distress, Rheumatoid factor positive, Streptococcal identification test negative, Syphilis test negative, Virus culture
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Arthralgia, Biopsy bronchus abnormal, Biopsy kidney abnormal, Bronchoalveolar lavage abnormal, Bronchoscopy
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Chest X-ray normal, Computerised tomogram thorax abnormal, Cough, Diffuse alveolar damage, Glomerulonephritis rapidly progressive
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Haemoptysis, Henoch-Schonlein purpura, Inflammation, Macrophages increased, Oedema peripheral
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Pain, Pitting oedema, Pleural effusion, Proteinuria, Pulmonary alveolar haemorrhage
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Rash erythematous, Renal failure acute, Respiratory distress
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Acute respiratory distress syndrome, Arthralgia, Biopsy kidney abnormal, Biopsy lung, Bronchial haemorrhage
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Bronchoalveolar lavage abnormal, Bronchoscopy, Chest X-ray normal, Computerised tomogram abnormal, Cough
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Diffuse alveolar damage, Glomerulonephritis rapidly progressive, Haemoptysis, Henoch-Schonlein purpura, Inflammation
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.
Age: 26.0
Sex: M
Vaccine: HEP, HEP, HEP
Symptoms: Laboratory test abnormal, Lung infiltration, Macrophages increased, Oedema peripheral, Pain
Clinical narrative: This case was reported in a literature article and described the occurrence of Henoch-Schonlein purpura in a 26-year-old male subject who was vaccinated with HEPATITIS B vaccine (manufacturer unspecified). On an unspecified date, the subject received unspecified dose of HEPATITIS B vaccine (unknown route and injection site), lot number not provided. One week after vaccination with HEPATITIS B vaccine, the subject experienced arthralgias, bilateral lower extremity edema and a painful erythematous rash. The physical examination revealed normal vital signs and a comfortable appearing subject. He had multiple healing erythematous papules on the lower extremities and moderate pitting edema of the feet and ankles. Initial laboratory studies were remarkable for acute renal failure and nephrotic range proteinuria. The subject was hospitalised. At admission, the chest X-ray was normal. On the second day of admission, the patient developed acute respiratory distress with cough and hemoptysis. At that time, computed tomography (CT) of the chest demonstrated bilateral patchy infiltrates and pleural effusions. Bronchoscopy was performed and serial bronchoalveolar lavages returned increasingly bloody aliquors and numerous hemosiderin-laden macrophages. Transbronchial biopsy demonstrated gross hemorrhage, destruction of the alveolar architecture and acute and chronic inflammation. These studies, combined with the patient's clinical course and chest CT, confirmed a diagnosis of diffuse alveolar hemorrhage (DAH). A subsequent renal biopsy revealed diffuse crescentic glomerulonephritis and mesangial immunoglobulin A (IGA) deposition, establishing a diagnosis of Henoch-Schonlein purpura (HSP). The subject was treated with cyclophosphamide and corticosteroid. After treatment with corticosteroids and cyclophosphamide, the DAH resolved and the glomerulonephritis stabilized. At the time of reporting the outcome of the events was unspecified. The author considered the events were possibly related to vaccination with HEPATITIS B vaccine.