Age: 74.0
Sex: F
Vaccine: COVID19, UNK
Symptoms: Arthralgia, Condition aggravated, Gait disturbance, Mobility decreased, Neurological symptom
Clinical narrative: diagnosed with tendinopathy/ excruciating pain in right knee/ swelling in right knee; elbow pain exacerbated after taking Covid booster; elbow pain exacerbated after taking Covid booster; Couldn't even walk, could not put any weight on it, had to use brace.; limited in mobility; Was affected neurologically somehow; This is a spontaneous report received from a Consumer or other non HCP.  A 74-year-old female patient received BNT162b2 omi xbb.1.5 (COMIRNATY (2023-2024 FORMULA)), on 07Nov2023 as dose 1, single (Batch/Lot number: unknown) at the age of 74 years, in left arm for covid-19 immunisation; ezetimibe (EZETIMIBE), since May2023) at 10 mg (10 mg (alternate cholesterol lowering drug)) for blood cholesterol increased. The patient's relevant medical history included: "elbow pain", start date: Jun2023 (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: flu vaccine (had flu shot about a week before the Covid booster, at doctor's office), administration date: 01Nov2023, when the patient was 74-year-old, for immunization; comirnaty (DOSE 1, Batch/Lot number: EN6201, Anatomical Site of injection: left arm), administration date: 08Feb2021, when the patient was 71-year-old, for COVID-19 immunization; comirnaty (DOSE 2, Batch/Lot number: EN6205, Anatomical Site of injection: left arm), administration date: 01Mar2021, when the patient was 71-year-old, for COVID-19 immunization; comirnaty (DOSE 3, Anatomical Site of injection: left arm), administration date: 05Oct2021, when the patient was 72-year-old, for COVID-19 immunization. The following information was reported: NEUROLOGICAL SYMPTOM (non-serious) with onset 2023, outcome "unknown", described as "Was affected neurologically somehow"; GAIT DISTURBANCE (non-serious) with onset Nov2023, outcome "unknown", described as "Couldn't even walk, could not put any weight on it, had to use brace."; ARTHRALGIA (non-serious), CONDITION AGGRAVATED (non-serious) all with onset Nov2023, outcome "unknown" and all described as "elbow pain exacerbated after taking Covid booster"; MOBILITY DECREASED (non-serious) with onset Nov2023, outcome "unknown", described as "limited in mobility"; TENDON DISORDER (non-serious) with onset 17Nov2023, outcome "unknown", described as "diagnosed with tendinopathy/ excruciating pain in right knee/ swelling in right knee". Relevant laboratory tests and procedures are available in the appropriate section. The action taken for ezetimibe was dosage permanently withdrawn. Therapeutic measures were taken as a result of tendon disorder, gait disturbance. Therapeutic measures were not taken as a result of arthralgia, condition aggravated.  Additional information: It was reported that the newest covid booster might have had adverse effect. Patient got it on 07Nov2023 then, like a week later, knees kind of felt funny, just like something was in them. Something felt loose, was just weird. Then, out of the blue, was like a knife went through her right knee. She hadn't sprained it or fallen or anything. Clarified this was the excruciating pain in right knee that started 17Nov2023. Has elbow pain on unspecified date in Nov2023, just those pervasive joints. Patient couldn't even walk, could not put any weight on it, had to use brace. It was also reported that patient was going a plane and had to use wheelchair. Got back, got x-ray after that, said she got tendinopathy. It is slowly resolving, got swelling in right knee. Patient also stated, "The left knee is so, so, elbow hurts." Patient reported that he stopped cholesterol medicine right away; that drug also might have had part to play. It was also reported that patient had flu shot about a week before the Covid booster. Thinks all of this pushed her over the edge. Was perfectly fine before that. Still experiencing limitation in right knee, there is swelling and today, had pain but, was walking without knee brace, sometimes, without cane. Clarified, it was tendinopathy, not tendonitis or tendinosis. That is what the x-ray showed. Still limited in mobility, if she doesn't think about where she is walking or putting a step down. Especially at night, feels more swelling, hard to turn over. Left knee is ok. Could tell something is going on there. As a treatment, patient was just taking Ibuprofen, Advil, rubbing on anti-inflammatory cream on knee. It was also clarified that the pain in right elbow started little bit in Jun2023, does not know. It seemed to exacerbate with this. Clarified, right elbow pain started Jun2023, prior to Pfizer Covid booster, exacerbated after taking Pfizer Covid booster. No treatment for elbow pain; thinks with getting older, tweaked it or something. Is there every day, thought as part of age. X-ray confirmed tendinopathy 28Nov2023. Clarified, previous Covid vaccines all Pfizer vaccines. Never had problems with those. Might have had a little down time with first one, nothing that wouldn't be deemed not usual. Clarified, 4th dose is last dose caller just had. Patient also reported that he was affected neurologically somehow, just wondering if there was any kind of muscle biopsy or test that exists that would be relevant to this.  The information on the batch/lot number for BNT162b2 omi xbb.1.5 will be requested and submitted if and when received.