Age: 66.0
Sex: F
Vaccine: COVID19
Symptoms: COVID-19, SARS-CoV-2 test
Clinical narrative: Got covid after getting three doses of Covid vaccine; This spontaneous case was reported by a patient and describes the occurrence of COVID-19 (Got covid after getting three doses of Covid vaccine) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 032F21A, 040B21A and 001A21A) for COVID-19 prophylaxis.    Co-suspect product included non-company product NIRMATRELVIR, RITONAVIR (PAXLOVID) for COVID-19 treatment.    Concomitant products included ATORVASTATIN CALCIUM (LIPITOR) for an unknown indication.   On 15-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 12-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .25 milliliter. On 12-Jul-2022, the patient started NIRMATRELVIR, RITONAVIR (PAXLOVID) (unknown route) at an unspecified dose. On 12-Jul-2022,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced COVID-19 (Got covid after getting three doses of Covid vaccine). At the time of the report, COVID-19 (Got covid after getting three doses of Covid vaccine) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 12-Jul-2022, SARS-CoV-2 test: (Positive) Positive. On 30-Jul-2022, SARS-CoV-2 test: (Positive) Positive.         Patient Ethnicity reported. No other conditions reported. Patient heard it was about 5 to 10 percent of people getting rebound Covid and patient one of those people. Patient was taking Paxlovid, and felt great, it works great. Patient was on Lipitor but patient did stop taking it during the Paxlovid treatment per her doctor's instruction. She was on 10mg one time a day by mouth. Patient received two initial doses and one booster of Moderna Vaccine.  No treatment medication provided.  Company comment  This Spontaneous case reported by patient concerns a 66 years old female patient, with no reported medical history, who experienced the unexpected, non-serious AESI of COVID-19 (Got covid after getting three doses of Covid vaccine) about 08 months after receiving the 3 dose of mRNA-1273 vaccine in the COVID-19 vaccination series. Patient previously received 2 primary doses of Moderna vaccine given at an interval of 28 days, with the last dose given about 6 months and 20 days prior to the 3 dose. It was reported that the patient was tested positive for SARS-CoV-2 test on 12-July-2022 and the patient was started Nirmatrelvir, Ritonavir (PAXLOVID). SARS-CoV-2 test was done on 30 Jul 2022 and she was tested positive again, after treatment with paxlovid. No other information is available in the report. Ongoing Covid 19 pandemia and use of Paxlovid are confounders. The outcome of the event was reported as not known. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This Spontaneous case reported by patient concerns a 66 years old female patient, with no reported medical history, who experienced the unexpected, non-serious AESI of COVID-19 (Got covid after getting three doses of Covid vaccine) about 08 months after receiving the 3 dose of mRNA-1273 vaccine in the COVID-19 vaccination series. Patient previously received 2 primary doses of Moderna vaccine given at an interval of 28 days, with the last dose given about 6 months and 20 days prior to the 3 dose. It was reported that the patient was tested positive for SARS-CoV-2 test on 12-July-2022 and the patient was started Nirmatrelvir, Ritonavir (PAXLOVID). SARS-CoV-2 test was done on 30 Jul 2022 and she was tested positive again, after treatment with paxlovid. No other information is available in the report. Ongoing Covid 19 pandemia and use of Paxlovid are confounders. The outcome of the event was reported as not known. The benefit-risk relationship of mRNA-1273 is not affected by this report.