Sex: M
Vaccine: COVID19
Symptoms: Arthropathy, Blood pressure increased, Blood pressure measurement, Cardiac disorder, Chills
Clinical narrative: HEART ABLATION; KNEE SURGERY; BLOOD PRESSURE INCREASE; PAIN/ SORE ARM; CHILLS; This is a spontaneous report received from a Consumer or other non HCP. Other Case identifier(s): US-BRISTOL-MYERS SQUIBB COMPANY-2023-178932.  This case was received via Pfizer Inc (Reference number: PV202300198878) on 07-Dec-2023. Information was received from a Consumer/other non health professional concerning a 7 Decade(s) old Male patient, enrolled in the post-marketing study A solicited program in which a patient received a product who received Suspect product APIXABAN for Product used for unknown indication, lot number: Unknown; Suspect product COVID-19 VACCINE for Product used for unknown indication, lot number: Unknown. On an unknown date, the patient had cardiac disorder (heart ablation), which met the following seriousness criteria: medical significance. Treatment included heart ablation. The outcome of the cardiac disorder was unknown. On an unknown date, the patient had arthropathy (knee surgery), which met the following seriousness criteria: medical significance. Treatment included knee surgery. The outcome of the arthropathy was unknown. On an unknown date, the patient had blood pressure increased (blood pressure increase), which was considered non-serious. It is unknown if treatment was provided. The outcome of the blood pressure increased was unknown. On an unknown date, the patient had pain in extremity (pain/ sore arm), which was considered non-serious. It is unknown if treatment was provided. The pain in extremity was resolving. On an unknown date, the patient had chills (chills), which was considered non-serious. It is unknown if treatment was provided. The outcome of the chills was unknown. Patient taking Eliquis experienced blood pressure increased, had recent heart ablation and knee surgery and experienced pain and chills from COVID vaccine. Patient just got a little bit of the chills and then patient went to bed that night, woke up the next morning and its pretty much gone and had a sore arm. The action taken with APIXABAN medication was unknown. The action taken with COVID-19 VACCINE medication was unknown. Medical history and concurrent conditions included cardiac ablation and knee operation. Concomitant medications were not reported. Relevant Laboratory & other Diagnostic Tests On an unknown date, BLOOD PRESSURE: increased. The reporter did not provide a causality assessment for events cardiac disorder, arthropathy, blood pressure increased, pain in extremity and chills to APIXABAN. The reporter did not provide a causality assessment for events cardiac disorder, arthropathy and blood pressure increased to COVID-19 VACCINE. The reporter considered events pain in extremity and chills related to COVID-19 VACCINE. Consent to contact consumer/other non health professional for follow-up information was denied. Tracking of Changes: 05-Dec-2023: Initial information was received.  Causality Assessment: Drug: ELIQUIS, Event: Blood pressure increased, Heart disorder, Knee arthropathy, Pain in arm, Chills; Per Reporter: No Information; Per Company: Not Related. Drug: COVID-19 VACCINE, Event: Blood pressure increased, Heart disorder, Knee arthropathy; Per Reporter: No Information, Per Company: Not Related. Event: Pain in arm, Chills, Per Reporter: Related, Per Company: Not Related.  Comment: This patient had cardiac disorder and arthropathy while on apixaban therapy. Co-suspect include Covid-19 vaccine. Based on the nature of the events, cardiac disorder (heart ablation) and arthropathy (knee surgery) are considered as not related due to absence of biological plausibility.  No follow-up attempts are possible. Batch/lot number is not provided, and it cannot be obtained.  Apixaban is under agreement.