Age: 74.0
Sex: M
Vaccine: VARZOS, VARZOS
Symptoms: Extra dose administered, Pruritus, Rash, Scar
Clinical narrative: rash /a new one comes in clusters /  areas: shoulder, back, chest, stomach, one arm, neck, right lower leg and knee; itching; rash : "It jumps around to different locations 3 to 4 days it gets better and leaves a scar / areas: shoulder, back, chest, stomach, one arm, neck, right lower leg and knee; 1st injection on September 24th, 2nd injection on October 6th,; the 3rd injection on 3rd  November 2020; This case was reported by a consumer via call center representative and described the occurrence of rash in a 74-year-old male patient who received Herpes zoster (Shingrix) (batch number Z4359, expiry date 19th September 2021) and (batch number 2E4SZ, expiry date 26th November 2021) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis and Herpes zoster (Shingrix) for prophylaxis.   Concurrent medical conditions included diabetes, cardiovascular disease, unspecified (Blood Pressure) and macular degeneration (received injection in his right eye). Concomitant products included ascorbic acid (Vitamin C), vitamin d, magnesium hydrogen aspartate dihydrate (Magnesium), insulin glargine (Lantus), atorvastatin calcium (Lipitor), omeprazole (Prilosec (Omeprazole)), famotidine (Pepcid (Famotidine)), insulin aspart (Novolog), metformin, metoprolol, thyroid medication {nos} (Thyroid Medication), sacubitril + valsartan (Entresto) and acetylsalicylic acid (Aspirin).   On 24th September 2020, the patient received the 1st dose of Shingrix. On an unknown date, the dose was an unknown dose. On 6th October 2020, the patient received the 2nd dose of Shingrix. On 3rd November 2020, the patient received the 3rd dose of Shingrix. On an unknown date, less than a week after receiving Shingrix and not applicable after receiving Shingrix and Shingrix, the patient experienced rash, pruritus, scar, drug dose administration interval too short and extra dose administered. The patient was treated with camphor, menthol (Sarna Lotion), hydroxyzine hydrochloride (Hydroxyzine Hcl), benadryl (nos) (Benadryl), cyproheptadine and triamcinolone (Triamcinolone Cream). On an unknown date, the outcome of the rash was not recovered/not resolved and the outcome of the pruritus, scar, drug dose administration interval too short and extra dose administered were unknown.   It was unknown if the reporter considered the rash, pruritus and scar to be related to Shingrix.  Additional details were reported as follows: Healthcare professional care ordered patient to discontinue his Vitamins D and C, Magnesium, Lipitor, Prilosec (Omeprazole) and Pepcid (Famotidine) medications for 2 weeks and was told to continue all his diabetic medications (Novolog, Lantus, Metformin), his Blood Pressure and Cardiovascular medications (Metoprolol Aspirin, Entresto) and his Thyroid medication. Patient stated that he gets an injection in his right eye for his Macular degeneration. On 24th September 2020, the patient received 1st dose of Shingrix and experienced itching and rash. Patient stated that about rash that it jumps around to different locations 3 to 4 days it gets better and leaves a scar then a new one comes in clusters and patient described that it had affected the shoulder, back, chest, stomach, one arm, neck, right lower leg and knee. Patient reported the it had been 1.5 months and for 1 or 2 days he was fine and then more rash clusters come out again. Reporter stated that it was unbearable and a frustrated anguish. Patient was prescribed medications for itching and rash with Sarna Lotion, Benadryl, Triamcinolone 0.1 percent cream, Hydroxyzine HCl 25 mg, Cyproheptadine 4 mg. On 6th October 2020, the patient received 2nd dose of shingrix, which was sooner than the recommended interval, which led to shortening of vaccination schedule. On 3rd November 2020, the patient received 3rd dose of shingrix, which let to extra dose administered. The reporter consented to follow up.