Age: 20.0
Sex: F
Vaccine: HPV4
Symptoms: Neuralgia, Pain, Pain in extremity, Peripheral swelling, Rash
Clinical narrative: angioedema/foot swelling; Neck pain/finger pain/fatigue/Joint pain/Fibromyalgia/chronic pain/trouble focusing; small bumps on her thighs which gradually worsened and progressed into full body hives and welts which lasted for two months. The hives continued past the two months intermittently on different areas of her body.; slurred speech; experienced difficulty getting out of bed and standing was painful.; nerve pain.; including but not limited to autonomic, autoimmune, and neurological injuries and resulting; This initial spontaneous report was received from a lawyer and the consumer regarding a case in litigation and refers to an adult female patient of unknown age. The patient's medical history, concurrent conditions and concomitant medications were not reported.   On unspecified date, when the patient was 20 years old, the patient was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) (strength, dose, lot #, expiry date, anatomical location and route of administration were not provided) administered for for preventing cervival cancer. On unspecified date, the patient was vaccinated with the second and thrid doses of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). It was confirmed that a physician recommended that patient receive the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, which was touted as a safe and effective vaccine.  On an unknown date, following her injection, the patient  experienced neck pain, finger pain, fatigue, joint pain, chronic pain, trouble focusing (fibromyalgia), small bumps on her thighs which gradually worsened and progressed into full body hives and welts which lasted for two months. The hives continued past the two months intermittently on different areas of her body (urticaria), foot swelling as a symptom of angioedema, slurred speech (dysarthria), difficulty getting out of bed and standing was painful (dysstasia), and nerve pain (neuralgia).  As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the patient had been unable to engage in activities that a normal young person would enjoy. After receiving the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, patient had been unable to enjoy hobbies such as rock climbing and photography.   Patient contends that her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological injuries, including but not limited to to autonomic, autoimmune, and neurological injuries (autoimmune disorder) and resulting sequalae that patient sustained as a result of receiving the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine.  The patient has suffered and continued to suffer severe and permanent physical injuries, and associated symptomatology and has suffered severe and permanent emotional injuries, including pain and suffering, therefore the outcome of all the events was considered as not recovered.  The causality between quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) and all the aforementioned events was reported as related and were also considered as disability events.  The primary reporter considered all adverse events as medically significant. Upon internal review, angioedema and autoimmune disorder were determined to be medically significant event.