Age: 64.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Arthritis, Condition aggravated, Joint swelling, Pain in extremity
Clinical narrative: This spontaneous case was reported by a patient and describes the occurrence of CONDITION AGGRAVATED (Had this since April 2021, only it got worst), PERIPHERAL SWELLING (Swelling in fingers), ARTHRITIS (Had swelling & pain in fingers, like arthritis/ swelling & pain in  joints, like arthritis), JOINT SWELLING (Swelling in  joints) and PAIN IN EXTREMITY (Had Pain in fingers) in a 64-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 012H21B, 021B21A and 030A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. Allergies to medications, food and other products were unknown. It was unknown if patient had ever COVID positive test or diagnosed with it. It was unknown history relating to mentioned adverse event and both Acute and Chronic illnesses at the time of vaccination. Other vaccines given within 1 month prior to Moderna COVID-19 vaccine was unknown. On 03-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 04-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 31-Mar-2021, the patient experienced PERIPHERAL SWELLING (Swelling in fingers), ARTHRITIS (Had swelling & pain in fingers, like arthritis/ swelling & pain in  joints, like arthritis), JOINT SWELLING (Swelling in  joints), PAIN IN EXTREMITY (Had Pain in fingers) and ARTHRALGIA (Pain in  joint). On 17-Aug-2022, the patient experienced CONDITION AGGRAVATED (Had this since April 2021, only it got worst). At the time of the report, CONDITION AGGRAVATED (Had this since April 2021, only it got worst), PERIPHERAL SWELLING (Swelling in fingers), ARTHRITIS (Had swelling & pain in fingers, like arthritis/ swelling & pain in  joints, like arthritis), JOINT SWELLING (Swelling in  joints), PAIN IN EXTREMITY (Had Pain in fingers) and ARTHRALGIA (Pain in  joint) had not resolved. No concomitant product use was provided. The patient had no complaints after first dose. The patient had also experienced swelling & pain in fingers, like arthritis, swelling & pain in joints, like arthritis after 1st booster on 04-Dec-2021. The adverse event did not cause patient to seek medical care. The patient had experienced a similar event in the past.  The symptoms had worsened. No treatment medication was provided. Company comment: This is a spontaneous case concerning a 64-year-old, female patient with no reported medical history. The patient experienced the unexpected non-serious event of arthritis (had swelling & pain in fingers, like arthritis/ swelling & pain in  joints, like arthritis), the unexpected non-serious events of swelling in fingers, joint swelling, pain in fingers, arthralgia, and condition aggravated (had this since April 2021, only it got worst). It was reported that the patient received first dose of mRNA-1273 vaccine with no adverse event. The patient received second dose of mRNA-1273 vaccine 28 days after the first dose. It was reported that the patient experienced "swelling and pain in fingers, like arthritis" and "swelling and pain in joints, like arthritis" on the same day with the first dose of mRNA-1273 vaccine administration. The events were reported as not resolved. The patient received first booster dose approximately 248 days after the second dose. It was reported that the patient experienced the exact same symptoms of "swelling and pain in fingers, like arthritis" and "swelling and pain in joints, like arthritis" on the same day with the first booster dose of mRNA-1273 vaccine administration. Approximately 256 days after the first booster dose of mRNA-1273 vaccine administration, the patient experienced condition aggravated (had this since April 2021, only it got worst). It was reported that the patient did not sought consult. No further clinical information was available for medical review. The events were reported as not resolved. The patient's age and gender remain confounders for all the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report. Sender's Comments: This is a spontaneous case concerning a 64-year-old, female patient with no reported medical history. The patient experienced the unexpected non-serious event of arthritis (had swelling & pain in fingers, like arthritis/ swelling & pain in  joints, like arthritis), the unexpected non-serious events of swelling in fingers, joint swelling, pain in fingers, arthralgia, and condition aggravated (had this since April 2021, only it got worst). It was reported that the patient received first dose of mRNA-1273 vaccine with no adverse event. The patient received second dose of mRNA-1273 vaccine 28 days after the first dose. It was reported that the patient experienced "swelling and pain in fingers, like arthritis" and "swelling and pain in joints, like arthritis" on the same day with the first dose of mRNA-1273 vaccine administration. The events were reported as not resolved. The patient received first booster dose approximately 248 days after the second dose. It was reported that the patient experienced the exact same symptoms of "swelling and pain in fingers, like arthritis" and "swelling and pain in joints, like arthritis" on the same day with the first booster dose of mRNA-1273 vaccine administration. Approximately 256 days after the first booster dose of mRNA-1273 vaccine administration, the patient experienced condition aggravated (had this since April 2021, only it got worst). It was reported that the patient did not sought consult. No further clinical information was available for medical review. The events were reported as not resolved. The patient's age and gender remain confounders for all the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.