Age: 50.0
Sex: F
Vaccine: COVID19
Symptoms: Peripheral swelling, Pyrexia, Skin warm, Tenderness
Clinical narrative: 3/15/21: Within a few hours of the vaccine, I felt fatigued, followed by chills, severe body aches, fever, and dehydration (in that order). Improved by Day 5. 4/5/21:  Lump on left thigh appeared. Raised up, hard, red, and warm.  Went to  Clinic  ER immediately. Ultrasound of area and blood work showed no obvious abnormalities. Symptoms were diagnosed as "insect bite". Lump became painful several hours later. Antibiotics, Benadryl, and Corticortisone prescribed for 10 days. Took medication as instructed. Improvement by Day 7. Lump shrunk but did not completely resolve. Swelling and pain gone.  Completed medication on 4/15/21. 4/22/21:  Lump returned on left thigh, quickly turning into a large, solid mass. Red, warm, more swollen than the first time, and more tender to the touch and painful.  4/23/21:  Went to Walk-In Clinic , Nurse Practitioner ordered MRI and more blood work. 4/25/21:  Lump appeared on right thigh, same characteristics as the left thigh, also quickly turning into a large mass. Very painful. Hip size increased from 40 to 42 inches within a few days from the swelling.  Unable to wear underwear due to how excruciatingly painful the area(s) were.  Painful to sit, painful to stand up, painful to remain standing. Sharp shooting pains. Legs would feel as though they would give in if I stayed standing up too long. 4/28/21: Returned to Walk-In Clinic due to unbearable pain and nightly fevers. Antibiotics were prescribed on this visit, and a referral to a general surgeon and a Hematologist were made by the Nurse Practitioner who tended to me, . 5/3/21:  Went to see Orthopedic Surgeon Dr. . He reviewed the MRI with me and showed me the areas where fluid was all over in the area affected (thigh). Referred me to Dr. , Rheumatologist. 5/4/21:  Dr.  examined both thighs and determined a biopsy under general anesthesia was needed in order to do deep tissue removal. He also ordered more blood work.  5/4/21:  Initiated surgery preparations: Lab work, COVID testing, EKG, Chest X-Ray, Visit with General Practitioner to be cleared for the surgical procedure, Visit with surgery department.  5/6/21:  Surgical biopsy under general anesthesia performed. 5/13/21: Visit with Dr.  to remove surgical gauze, and examine the area.  5/14/21:  Visit with Dr.  for pathology / biopsy results.  I was informed that inflammation levels in my body were at 45%, where they should normally be at 8%.  Pathology concluded that an external cause was to blame for the inflammation, further stating that it was a foreign substance consistent with silicone injected in the area.  It is noted that I have no silicone implants in any part of my lower body. Nor have I had any silicone injected in my thighs. 5/17/21:  While using a pair of scissors and exercising normal pressure to cut a paper tag from new clothing, the area below my right thumb suddenly became swollen, purplish, and extremely tender. After two hours of no improvement, went to  Health where they took an X-ray and determined it was a Sprain.  I did not exercise any force to justify a sprain in that region. I was prescribed cortisone for 6 days. 5/20/21:  Follow up visit with Dr. , Rheumatologist, for second opinion on pathology results. Dr.  ordered blood work done in-office, as well as ordered additional blood work to be done at the lab.  Results pending. After also examining all of my blood work done up until that point, she deduced that the issue with my hand was also likely caused by inflammation in my body,  and whatever is causing the swelling in my thighs. The area of the hand turned black and blue the likes of severe trauma, yet there was no blunt force to the area. At the time of this reporting, I continue on blood thinner and anti-inflammatory medication for another 10 days to complete the 30 days post surgery. Additional blood work has been ordered to measure the inflammation levels and proceed accordingly.  Currently I feel throbbing in my legs mostly at night when I lie down. Prior to the Johnson & Johnson COVID-19 Vaccine, I had no medical issues. My only visits were routine control visits annually. I do not drink or smoke; and exercise regularly (until this happened).