Age: 16.0
Sex: F
Vaccine: TYP, YF
Symptoms: Asthenia, Blood potassium normal, Blood sodium normal, Cerebral atrophy, Computerised tomogram head abnormal
Clinical narrative: headache; weakness; injection site reaction (Such as pain); injection site reaction (such as tenderness); Injection site reaction (Such as redness); Injection site reaction (Such as swelling); muscle pains; Initial information was received on 20-Jul-2023 regarding an unsolicited valid Legal non-serious case received from a lawyer.  This case involves a 16 years old female patient who experienced headache, weakness, injection site reaction (such as pain), injection site reaction (such as tenderness), injection site reaction (such as redness), injection site reaction (such as swelling) and muscle pains after receiving yellow fever vaccine [YF-VAX] and typhoid VI polysaccharide vaccine [Typhim VI].  The patient's past medical history included Encephalitis on 29-APR-2020 and Magnetic resonance imaging head abnormal on 29-APR-2020. The patient's past vaccination(s) included SARS-COV-2 VACCINE on 27-AUG-2003, HPV VACCINE on 27-FEB-2014, HEPATITIS B VACCINE, HAEMOPHILUS INFLUENZA TYPE B VACCINE, MMR, POLIO VACCINE, VARICELLA VACCINE, HEPATITIS A VACCINE, MENINGOCOCCAL CONJUGATE, ROTAVIRUS VACCINE and DTAP on 12-APR-2024. The patient's family history included Anxiety/Depression with older sister and Depression with older sister. The patient's past medical treatment(s) was not provided. At the time of the event, the patient had ongoing Multiple sclerosis on 20-APR-2021, Steroid therapy on 29-APR-2020, Bipolar disorder on 28-MAR-2020, Mania on 28-MAR-2020 and Kluver-Bucy syndrome on 31-OCT-2022.  Concomitant medications included GABAPENTIN, QUETIAPINE, SERTRALINE and CHOLECALCIFEROL.  On 18-Feb-2020, the patient received an unknown dose of suspect yellow fever vaccine (Solution for injection) (lot R3L28TV) and 0.5 ml dose of suspect typhoid VI polysaccharide vaccine (Solution for injection) (lot, expiry date, strength, was unknown) via unknown route in unknown administration site for prophylactic vaccination (Immunisation).  On an unknown date the patient had headache, weakness (asthenia), injection site reaction (such as pain) (vaccination site pain), injection site reaction (such as tenderness) (vaccination site pain), injection site reaction (such as redness) (vaccination site erythema), injection site reaction (such as swelling) (vaccination site swelling) and muscle pains (myalgia) (unknown latency) following the administration of yellow fever vaccine and Typhoid VI polysaccharide vaccine.  Relevant laboratory test results included: Blood potassium (3.5 - 5.5 mmol/L) - On 16-Jan-2023: 3.6 mmol/L Blood pressure measurement - On 16-Jan-2023: 100/54 Blood sodium (133 - 145 mmol/L) - On 16-Jan-2023: 137 mmol/L Body temperature - On 16-Jan-2023: 36.3 Cel Computerised tomogram - On 16-Jan-2023:  [Subtle poorly defined scattered areas of white matter low attenuation bilaterally which have progressed. Mild interval volume loss of the brain since March 27, 2021. Nonspecific white matter changes such as demyelinating disease, vasculitis, postinfectious or inflammatory process or remote trauma are additional differential considerations. MRI without and with contrast may be helpful for further evaluation as clinically warranted. Paranasal sinus disease.] Heart rate - On 16-Jan-2023: 77 Oxygen saturation - On 16-Jan-2023: 99% Respiratory rate - On 16-Jan-2023: 18  Action taken: not applicable.  It is unknown if the patient experienced any additional symptoms/events.  It was not reported if the patient received a corrective treatment for the events.  At time of reporting, the outcome was Unknown for the events.