Age: 79.0
Sex: F
Vaccine: FLU4, UNK
Symptoms: Computerised tomogram, Diarrhoea, Gastrointestinal tube insertion, Ileus, Intestinal obstruction
Clinical narrative: Ileus vs obstruction; Ileus vs obstruction; Never developed normal bowel movement; Passing gas; Liquid stools; This spontaneous case retrieved on 08-Nov-2021 from Vaccine Adverse Event Reporting System (VAERS) (reference number: 1807844-1), reported by other healthcare professional and concerned a 79-year-old, female patient.  The patient's concurrent conditions included allergy to milk, lumbar spinal stenosis, gastroesophageal reflux disease (GERD) and right upper quadrant pain (after riding her all-terrain vehicle (ATV) for 10 miles the day before). The patient's historical condition included heme-positive stools. The patient missed colonoscopy at multiple centers due to pandemic issues. The patient's concomitant medications included carboxymethylcellulose 0.5 percent drops and 1 percent gel for eyes, ketotifen fumarate 0.25 percent for eyes, ophtalmic ointment for eyes (mineral oil 20 percent, petroleum jelly 80 percent) and meloxicam, all used for unreported indications.  On 11-Oct-2021, the patient was vaccinated Fluad Quadrivalent (influenza vaccine, inactivated influenza virus surface antigen (subunit), egg-derived, mf59; route of administration: intramuscular, anatomical location: left arm; dose and indication: not reported). The batch number reported was 312845.  On 13-Oct-2021, two days after receiving Fluad Quadrivalent, the patient was admitted with profound ileus vs obstruction.  On an unknown date in Oct-2021, the patient had nasogastric (NG) suction, for one day. The patient underwent computed tomography (CT), small bowel follow through and multiple 3-way abdominal studies, that showed ileus vs obstruction. Small bowel follow through, also showed the contrast getting all the way to the colon but she was very slow to advance in her diet. The patient's white blood cell count (WBC) was never elevated and she required some supplemental potassium. It was reported that the patient never developed normal bowel movement but had liquid stools and was passing gas at the time.  On 21-Oct-2021, the patient left hospital, against medical advice.  The outcome of all events was unknown.   The reproter did not provide causality assessment.  All events were assessed as serious due to seriousness criteria of hospitalisation. Additionally the event of 'ileus' was considered to be medically significant by a Physician. Company Comment: A 79-year-old, female patient was vaccinated with Fluad Quadrivalent. Two days following vaccination, the patient was hospitalised due to profound ileus vs obstruction. The patient underwent computed tomography (CT), small bowel follow through and multiple 3-way abdominal studies, that showed ileus vs obstruction. It was reported that the patient never developed normal bowel movement but had liquid stools and was passing gas at the time. The patient's white blood cell count (WBC) was never elevated and she required some supplemental potassium. The patient's historical condition included heme-positive stools and her concurrent condition included right upper quadrant pain. The patient missed colonoscopy at multiple centres due to pandemic issues. Based on all information provided, and considering biological implausibility, causality for all events is assessed as not related.; Sender's Comments: A 79-year-old, female patient was vaccinated with Fluad Quadrivalent. Two days following vaccination, the patient was hospitalised due to profound ileus vs obstruction. The patient underwent computed tomography (CT), small bowel follow through and multiple 3-way abdominal studies, that showed ileus vs obstruction. It was reported that the patient never developed normal bowel movement but had liquid stools and was passing gas at the time. The patient's white blood cell count (WBC) was never elevated and she required some supplemental potassium. The patient's historical condition included heme-positive stools and her concurrent condition included right upper quadrant pain. The patient missed colonoscopy at multiple centres due to pandemic issues. Based on all information provided, and considering biological implausibility, causality for all events is assessed as not related.