Age: 29.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Headache, Hypertension, Injection site rash, Injection site urticaria, Nausea
Clinical narrative: BP of 176/126mmhg/persistent severe hypertension/continued severe elevation of BP of 178/130mmHg; intermittent chest pains; severe nausea; rash and hives on left side of arm where injection site was, as well as left side of face; rash and hives on left side of arm where injection site was, as well as left side of face; rash and hives on left side of arm where injection site was, as well as left side of face; rash and hives on left side of arm where injection site was, as well as left side of face; mild progressive headache; body aches; chills; fatigue; fever of 100 degree F; This is a spontaneous report from a contactable Other Health Professional (patient). A 29-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE) lot number: unknown, intramuscular in the left arm, first dose on 18Dec2020 12:30 at a single dose for immunisation. Medical history included ongoing gestational hypertension in 2016 that never recovered, with controlled hypertension, asthma/COPD, and seasonal/animal allergies. Concomitant medication included sertraline hydrochloride (ZOLOFT) and losartan. The patient is not pregnant. The patient previously took and had allergies to erythromycin and nitrous oxide. It was reported that within 20-30 minutes of receiving covid vaccine on 18Dec2020, the patient developed mild progressive headache, body aches, chills, fatigue, fever of 100 degree F. At approximately 8:00 p.m. same day of vaccination, she developed rash and hives on left side of arm where injection site was, as well as left side of her face. Immediately following this, she had intermittent chest pains in which she took a BENADRYL 25 mg with some relief. Next day (19Dec2020), progressive headache persisted to a severe headache, severe nausea, persistent chest pains and a BP of 176/126mmhg. Reported to a place for evaluation with persistent severe hypertension and severe headache treated by toradol, compazine, and Benadryl. She was released from the ER with improved blood pressures and reduced headache. The following day Sunday Dec2020, progressive and severe headache occurred with continued severe elevation of BP of 178/130mmHg. Current treatment of losartan 50 mg was increased to 100 mg to attempt control. She was then placed on chlorthalidone/amlodipine.  The events resulted in doctor or other healthcare professional office/clinic visit, Emergency room/department or urgent care. The outcome of the events mild progressive headache, body aches, chills, fatigue, fever of 100 degree F, rash and hives on left side of arm where injection site was, as well as left side of face, intermittent chest pains, severe nausea, and BP of 176/126mmhg/persistent severe hypertension/continued severe elevation of BP of 178/130mmHg was not recovered (reported as symptoms persist). The patient was not diagnosed with Covid 19 prior to vaccination and she had not been tested since vaccination.  Information on the lot/batch number has been requested.; Sender's Comments: Based on the compatible time association, the hypertension aggravated is possibly related to bnt162b2 administration. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees and Investigators, as appropriate.