Age: 65.0
Sex: F
Vaccine: COVID19
Symptoms: Biopsy skin, Blood gastrin, Blood test, Computerised tomogram intestine, Diarrhoea
Clinical narrative: A 2 year long explosive diarrhea episode with diarrhea after eating; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 66-year-old female patient received BNT162b2 (BNT162B2), on 01Nov2021 as dose 3 (booster), single (Lot number: FF2593) at the age of 65 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Hypothyroid" (unspecified if ongoing), notes: Hypothyroid; "Food skin test: Stringbeans/Greenbeans" (unspecified if ongoing), notes: Food skin test: Stringbeans/Greenbeans, RXN: +/- (Questionable response); "Food skin test: Histamine" (unspecified if ongoing), notes: Food skin test: Histamine, RXN: 2 (moderate allergic) - 3 (Highly allergic). Concomitant medication(s) included: NP THYROID oral taken for hypothyroidism (ongoing). Vaccination history included: BNT162b2 (DOSE 1, SINGLE , Anatomical site of injection: Right Arm, Batch/Lot number: EP7534, EXP:30Jul2021), administration date: 20Mar2021, when the patient was 64-year-old, for COVID-19 Immunization; BNT162b2 (DOSE 2, SINGLE , Anatomical site of injection: Right Arm, Batch/Lot number: EW0162, EXP:31Jul2021), administration date: 10Apr2021, when the patient was 64-year-old, for COVID-19 Immunization, reaction(s): "Diarrhea", "Granuloma annulare".  The following information was reported: DIARRHOEA (medically significant), outcome "unknown", described as "A 2 year long explosive diarrhea episode with diarrhea after eating". The patient underwent the following laboratory tests and procedures: Biopsy skin: (unspecified date) Unknown results; Blood gastrin (0-115): (03Feb2022) 27 pg/mL; Blood test: (unspecified date) nothing showed up; Computerised tomogram intestine: (unspecified date) CT enterograpgy look fine.; a volumetric pre- and post-contrast scan: (unspecified date) Unknown results; Somatostatin receptor scan: (03Feb2022) <21 pg/mL; Stool analysis: (unspecified date) nothing showed up on test; Urine analysis: (07Feb2022) 1.1 mg/l; Urine analysis (0.0-14.9): (07Feb2022) 3.0 mg/24h; Urine analysis: (unspecified date) Unknown results; Vasoactive intestinal polypeptide test (0.0-58.8): (03Feb2022) 28.0 pg/mL. Therapeutic measures were taken as a result of diarrhoea.   Clinical course: Clinical course: Within 4-5 days of receiving the second vaccine on 10Apr2021, patient began a 2 year long explosive diarrhea episode with diarrhea after eating from morning until 3 pm every day [only ate breakfast] which caused her to become homebound. Patient had stool tests, blood tests, treatment with antibiotics- nothing showed upon tests, treatment did not work. Clinical History was chronic diarrhea.  Vaccination Facility type was public health clinic. No Prior Vaccinations (within 4 weeks). No Specific Relevant test for Thromboembolic with Thrombocytopenia.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300091602 same patient/reporter, different vaccine dose;US-PFIZER INC-202300219761 same patient/reporter, different vaccine dose;