Age: 62.0
Sex: M
Vaccine: COVID19
Symptoms: Blindness, Chronic inflammatory demyelinating polyradiculoneuropathy
Clinical narrative: chronic inflammatory demyelinating polyneuropathy; He was loosing his eye sight/He was getting blind; This spontaneous case was reported by a patient and describes the occurrence of CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY (chronic inflammatory demyelinating polyneuropathy) and BLINDNESS (He was loosing his eye sight/He was getting blind) in a 62-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 031H21A, 015M20A and 030A21A) for COVID-19 prophylaxis.     Previously administered products included for Product used for unknown indication: Neurontin (He took it a lot time ago and but hasn't taken it in years.). Past adverse reactions to the above products included No adverse event with Neurontin. Concurrent medical conditions included Chronic inflammatory demyelinating polyneuropathy. Concomitant products included MORPHINE SULFATE and ALPRAZOLAM (XANAX) for an unknown indication.   On 15-Feb-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 15-Mar-2021, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 28-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY (chronic inflammatory demyelinating polyneuropathy) (seriousness criterion medically significant) and BLINDNESS (He was loosing his eye sight/He was getting blind) (seriousness criterion medically significant). The patient was treated with GABAPENTIN (NEURONTIN) at an unspecified dose and frequency. At the time of the report, CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY (chronic inflammatory demyelinating polyneuropathy) and BLINDNESS (He was loosing his eye sight/He was getting blind) outcome was unknown.            No concomitant medication was reported. It was reported that when he got the booster shot it started on the way home and has been doing it ever since, probably 3 months. It feels the patient was holding the end of a wire that has been stripped and plugged in wall. The patient went to the neurologist who has never seen anything like it. It feels from feet to head. The patient when hugged the wife and the wife can also feel it. Caller didn't know the date he got the booster. The doctor gave him some Neurontin for it and it does'nt work.  Neurontin: doesn't have the product on hand to provide NDC, lot, and expiry. It was filled not long ago. The patient took it a lot time ago, but hasn't taken it in years and just started taking it again. The patient it of strength: 300mg three times aday. The patient also took morphine sulfate 100mg and 1mg Xanax and that doesn't do it.  The patient was on those monthly because he has chronic inflammatory demyelinating polyneuropathy. Facility confirmed and Morphine Sulfate and Xanax are in pharmacy bottles. It was hard for the patient to get up because the patient s legs are bad. It was driving the patient out of the patient mind. The patient wants to blow head off. The patient was getting blind now and doesn't know what was happening. The patient was loosing the eye sight. It hasn't been very long ago that the patient's vision was pretty good.   This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company Comment:  This spontaneous case concerns a 62-year-old male patient with concurrent Chronic inflammatory demyelinating polyradiculoneuropathy, who experienced the unexpected, serious  (medically significant) adverse event of special interest Chronic inflammatory demyelinating polyradiculoneuropathy, and event of Blindness (reported as He was loosing his eye sight/He was getting blind) on unknown dates in the context of receiving a booster dose of mRNA-1273 vaccine.  Patient presented with symptoms described as feeling like he is holding the end of a wire that has been stripped and plugged in wall, and difficulty getting up.  Patient had been prescribed  Neurontin 300mg three times a day along with Morphine Sulfate and Xanax, all of which did not afford relief of symptoms.  Patient previously received a 2-dose primary series given 28 days apart, with the last dose administered 9 and a half months prior to current vaccine. The underlying Chronic inflammatory demyelinating polyradiculoneuropathy could be considered as contributing to the symptoms presented by the patient, thus remains a confounder . The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 62-year-old male patient with concurrent Chronic inflammatory demyelinating polyradiculoneuropathy, who experienced the unexpected, serious  (medically significant) adverse event of special interest Chronic inflammatory demyelinating polyradiculoneuropathy, and event of Blindness (reported as He was loosing his eye sight/He was getting blind) on unknown dates in the context of receiving a booster dose of mRNA-1273 vaccine.  Patient presented with symptoms described as feeling like he is holding the end of a wire that has been stripped and plugged in wall, and difficulty getting up.  Patient had been prescribed  Neurontin 300mg three times a day along with Morphine Sulfate and Xanax, all of which did not afford relief of symptoms.  Patient previously received a 2-dose primary series given 28 days apart, with the last dose administered 9 and a half months prior to current vaccine. The underlying Chronic inflammatory demyelinating polyradiculoneuropathy could be considered as contributing to the symptoms presented by the patient, thus remains a confounder . The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.