Age: 80.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Arthritis, Fall, Urticaria, Vaccination site erythema
Clinical narrative: she has arthritis in the knee and pain in the knee; Patient also fell and her knee was hurt last month, pain in the Knee; Patient also fell and her knee was hurt last month; same arm of the injection is hot and feels like it burns; same arm of the injection  itch but she don't want to scratch the zone.; same arm of the injection is a little swollen; redness on same arm of the injection; She has red welts same size of an egg, and they hurt; This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (she has arthritis in the knee and pain in the knee), FALL (Patient also fell and her knee was hurt last month), VACCINATION SITE WARMTH (same arm of the injection is hot and feels like it burns), VACCINATION SITE PRURITUS (same arm of the injection  itch but she don't want to scratch the zone.) and VACCINATION SITE SWELLING (same arm of the injection is a little swollen) in an 80-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 06SF21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Canker sores oral (Patient used to have canker sores in her mouth and took Riboflavin to treat it) and Oral lichen planus (in mouth) in 2016. Previously administered products included for Autoimmune disorder: cortisone muscular injection (cortisone muscular injection) in 2016, prednisone injection (prednisone injection was received inside her mouth) in 2016 and prednisone pills (prednisone pills); for Product used for unknown indication: SHINGRIX (vaccine caused an autoimmune disease in 2016 Oral lichen planus in her mouth which can not be cured.) in 2016. Past adverse reactions to the above products included Autoimmune deficiency syndrome with SHINGRIX; and No adverse event with cortisone muscular injection, prednisone injection and prednisone pills. Concurrent medical conditions included Diabetes, Thyroid disorder, Blood pressure fluctuation, Arrhythmia, Cholesterol, Gastritis, Urinary infection, Cardiovascular disorder and Knee arthritis. Concomitant products included PROPRANOLOL for Arrhythmia prophylaxis, LISINOPRIL for Blood pressure management, MONASCUS PURPUREUS (RED RICE YEAST) for Cardiovascular event prophylaxis, METFORMIN for Diabetes prophylaxis, OMEPRAZOLE for Gastritis prophylaxis, OMEGA-3 FATTY ACIDS, EZETIMIBE (ZETIA) and RIBOFLAVIN for Prophylaxis, CHLORTALIDONE (HIPREX [CHLORTALIDONE]) for Prophylaxis urinary tract infection, LEVOTHYROXINE for Thyroid therapy.   On 11-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 08-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 17-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 17-Nov-2021, the patient experienced VACCINATION SITE WARMTH (same arm of the injection is hot and feels like it burns), VACCINATION SITE PRURITUS (same arm of the injection  itch but she don't want to scratch the zone.), VACCINATION SITE SWELLING (same arm of the injection is a little swollen), VACCINATION SITE ERYTHEMA (redness on same arm of the injection) and URTICARIA (She has red welts same size of an egg, and they hurt). In April 2022, the patient experienced FALL (Patient also fell and her knee was hurt last month). On an unknown date, the patient experienced ARTHRITIS (she has arthritis in the knee and pain in the knee) and ARTHRALGIA (Patient also fell and her knee was hurt last month, pain in the Knee). The patient was treated with IBUPROFEN for Prophylaxis, at an unspecified dose and frequency. At the time of the report, ARTHRITIS (she has arthritis in the knee and pain in the knee), FALL (Patient also fell and her knee was hurt last month), VACCINATION SITE WARMTH (same arm of the injection is hot and feels like it burns), VACCINATION SITE PRURITUS (same arm of the injection  itch but she don't want to scratch the zone.), VACCINATION SITE SWELLING (same arm of the injection is a little swollen), VACCINATION SITE ERYTHEMA (redness on same arm of the injection), URTICARIA (She has red welts same size of an egg, and they hurt) and ARTHRALGIA (Patient also fell and her knee was hurt last month, pain in the Knee) outcome was unknown.            Concomitant medications Omega 3 vazopa and Zetia used for cholesterol.  Patient could not take statin. She was not allowed to take coffee chocolate anything spicy since 2016 to 2022 and she was isolated in her house to not get COVID.  She used to have canker sores in her mouth and took Riboflavin to treat it which made it went away in the past.  She complained about her doctor not prescribing prednisone. Patient also took Allergy medication.  Treatment medication also included Prosenogel. She also fell and her knee was hurt last month, and she has arthritis in the knee and pain in the knee and was taking Ibuprofen for that. Company comment: This Spontaneous case concerns an 80-year-old female patient with relevant Concurrent medical conditions of Knee arthritis, who experienced the unexpected nonserious AESI event of Arthritis which occurred on unspecified day after the fourth dose of mRNA-1273 vaccine. Patient's relevant Concurrent medical conditions of Knee arthritis remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2021-349728, MOD-2022-565215.   Most recent FOLLOW-UP information incorporated above includes: On 11-May-2022: Follow up received included medical history, suspect product details, concomitant drug, treatment medication, event fall and arthralgia, arthritis added and I-narrative updated. On 11-May-2022: Follow-up received contains no new information.; Sender's Comments: This Spontaneous case concerns an 80-year-old female patient with relevant Concurrent medical conditions of Knee arthritis, who experienced the unexpected nonserious AESI event of Arthritis which occurred on unspecified day after the fourth dose of mRNA-1273 vaccine. Patient's relevant Concurrent medical conditions of Knee arthritis remains a confounder. The benefit-risk relationship of mRNA-1273 is not affected by this report.