Age: 82.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Extra dose administered, Hypoaesthesia, Musculoskeletal pain, Paraesthesia
Clinical narrative: Patient received third dose of Shingrix; Tingling from her left arm all the way down to the left thumb; her thumb was numb; pain was feeling somewhere in the scapula; changes in blood pressure; now it is down to something; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of tingling of extremity in a 82-year-old female patient who received Herpes zoster (Shingrix) (batch number EB4E4, expiry date 26-SEP-2025) for prophylaxis.   The patient's past medical history included dizziness and change in blood pressure. Previously administered products included Shingrix with an associated reaction of no adverse event (on 27 January 2021 received 1st dose) and Shingrix with an associated reaction of no adverse event (on 16 June 2021 received 2nd dose).   On 02-OCT-2023, the patient received the 3rd dose of Shingrix. On 02-OCT-2023, an unknown time after receiving Shingrix, the patient experienced extra dose administered (Verbatim: Patient received third dose of Shingrix). In OCT-2023, the patient experienced tingling of extremity (Verbatim: Tingling from her left arm all the way down to the left thumb), numbness in fingers (Verbatim: her thumb was numb), scapula pain (Verbatim: pain was feeling somewhere in the scapula), change in blood pressure (Verbatim: changes in blood pressure) and feeling down (Verbatim: now it is down to something). The outcome of the tingling of extremity, numbness in fingers and scapula pain were not resolved and the outcome of the change in blood pressure and extra dose administered were unknown and the outcome of the feeling down was not reported.   The reporter considered the tingling of extremity and scapula pain to be related to Shingrix. It was unknown if the reporter considered the numbness in fingers, change in blood pressure and feeling down to be related to Shingrix.     The company considered the tingling of extremity and scapula pain to be related to Shingrix. It was unknown if the company considered the numbness in fingers, change in blood pressure and feeling down to be related to Shingrix.   Additional Information: GSK Receipt date: 10-JUN-2024 A Pharmacist reported that a patient had some side effects 1 week after getting a third dose of Shingrix (received without recalling having the second dose) which led to extra dose administered. Side effects started the very first week that patient received the third dose, it was causing tingling from her left arm all the way down to the left thumb, and her thumb was numb, she went to the doctor and they referred her for physical therapy (no medication given), then tingling and pain she was feeling somewhere in the scapula that was a result from the same vaccine it all cleared up, but same symptoms recurred and began again last week and are still ongoing, so she called to her prior pharmacy and they notified to her that she already received 2 doses of shingles vaccine before the third one.  Patient was prepared to go to the doctor one more time to see what next steps to take to treat symptoms.  Patient also mentioned that she felt dizziness but it was before the third dose, and now it was down to something that she could not remember the definition that the doctor mentioned (but it was not vertigo), related maybe to changes in blood pressure, that affects for example when she wake up from bed, she needs to sit down before she can move.  Reporter did not know if the 2 prior vaccines were also Shingrix, but they assumed it was Shingrix because there was no other shingles vaccine in the market as of now.