chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: QRS axis abnormal, Sinus bradycardia
Clinical narrative: Pt reported new onset, non-radiating, constant left-sided pressure-type chest pain accompanied by shortness of breath. Onset around 0600 pm 5/17/08 and got progressively worse during the day. Symptoms: Chest Pain, Dyspnea (shortness of breath).  6/20/08 Reviewed medical records including hospital records of 5/18-5/19/2008. FINAL DX: resolved noncardiac chest pain & tobacco abuse Records reveal patient experienced left precordial pain w/SOB.  Cardiology consult done.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: Cardiac stress test, Cardiac stress test normal, Chest discomfort, Chest pain, Electrocardiogram normal
Clinical narrative: Pt reported new onset, non-radiating, constant left-sided pressure-type chest pain accompanied by shortness of breath. Onset around 0600 pm 5/17/08 and got progressively worse during the day. Symptoms: Chest Pain, Dyspnea (shortness of breath).  6/20/08 Reviewed medical records including hospital records of 5/18-5/19/2008. FINAL DX: resolved noncardiac chest pain & tobacco abuse Records reveal patient experienced left precordial pain w/SOB.  Cardiology consult done.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: Laboratory test normal, Troponin
Clinical narrative: Pt reported new onset, non-radiating, constant left-sided pressure-type chest pain accompanied by shortness of breath. Onset around 0600 pm 5/17/08 and got progressively worse during the day. Symptoms: Chest Pain, Dyspnea (shortness of breath).  6/20/08 Reviewed medical records including hospital records of 5/18-5/19/2008. FINAL DX: resolved noncardiac chest pain & tobacco abuse Records reveal patient experienced left precordial pain w/SOB.  Cardiology consult done.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: Cardiac stress test normal, Chest X-ray normal, Chest discomfort, Dyspnoea, Electrocardiogram abnormal
Clinical narrative: Patient received Smallpox vaccine on 5/8/08, presented to FOB with CC chest pain/pressure on 5/17/08. He was then referred to ER where he was admitted for 2 days for observation and cardiology was obtained.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: QRS axis abnormal, Sinus bradycardia
Clinical narrative: Patient received Smallpox vaccine on 5/8/08, presented to FOB with CC chest pain/pressure on 5/17/08. He was then referred to ER where he was admitted for 2 days for observation and cardiology was obtained.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: Cardiac stress test, Cardiac stress test normal, Chest discomfort, Chest pain, Electrocardiogram normal
Clinical narrative: Patient received Smallpox vaccine on 5/8/08, presented to FOB with CC chest pain/pressure on 5/17/08. He was then referred to ER where he was admitted for 2 days for observation and cardiology was obtained.
Age: 27.0
Sex: M
Vaccine: ANTH, SMALL, SMALL
Symptoms: Laboratory test normal, Troponin
Clinical narrative: Patient received Smallpox vaccine on 5/8/08, presented to FOB with CC chest pain/pressure on 5/17/08. He was then referred to ER where he was admitted for 2 days for observation and cardiology was obtained.
Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Body temperature increased, Headache, Pain
Clinical narrative: Developed 99.0 temp, body aches, headache the day after ZOSTAVAX vaccine.  Sx lasted 3 days after vaccine.
Age: 76.0
Sex: M
Vaccine: TYP, YF
Symptoms: Headache, Nausea, Pyrexia, Vomiting
Clinical narrative: severe HA, fevers, nausea and vomiting
Age: 59.0
Sex: F
Vaccine: TYP, YF
Symptoms: Headache, Laboratory test normal, Nausea, Pyrexia, Vomiting
Clinical narrative: Febrile reaction with HA, nausea, vomiting.
Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Body temperature increased, Headache, Pain
Clinical narrative: Developed 99.0 temp, body aches, headache the day after ZOSTAVAX vaccine. Sx lasted 3 days after vaccine.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Asthenia, Chills, Fatigue, Myalgia, Nausea
Clinical narrative: Fever 103 for less than 24 hours. Muscle aches chills, nausea, weakness, fatigue, for 4 days.Did not seek medical attention. Fully recovered.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Pyrexia
Clinical narrative: Fever 103 for less than 24 hours. Muscle aches chills, nausea, weakness, fatigue, for 4 days.Did not seek medical attention. Fully recovered.
Age: 70.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site swelling, Mass, Rash, Swelling
Clinical narrative: patient reports less than 48 hours after vaccination a swollen lump and rash on left scalp area at hairline. The area did not itch or was painful. The actual arm that the vaccine was given in was left deltoid sc. That area was also red and swollen mildly.
Age: 11.0
Sex: M
Vaccine: TDAP
Symptoms: Autism, Condition aggravated, Headache, Pyrexia
Clinical narrative: Patient has regressive autism that began at 2years old.He received this vaccination and in 4 hours developed a fever to 104 and severe headache that lasted 12 hours.  I spoke with the Pediatrician's office and was told there was not much information as this was a new vaccine. I called the drug company(I am an MD A&I) who would not discuss this with me. Patient has had further significant regression over the last 2 and 1/2 years. 1/21/2010 Patient became progressively more dysfunctional in Neurological state both on a cognitive and motor level and verabal from this. This affect was profound and temporally related.
Age: 36.0
Sex: U
Vaccine: TDAP
Symptoms: Activities of daily living impaired, Contusion, Oedema peripheral, Pain in extremity
Clinical narrative: Three days after receiving shot, left elbow started swelling and a bruise appeared on same elbow. Could not move arm or hand. Had to bend arm in a 90 degree angle. Couldn't make a fist, everytime I tried to move a finger, I felt a sharp pain moving up to elbow. Lost use of left arm, needed help to get dressed and do other personal things. On Sunday June 8, left hand started swelling and pain was unbearable, went to work and manager sent me to hospital.
Age: 40.0
Sex: F
Vaccine: PPV
Symptoms: Blood culture, Computerised tomogram, Injected limb mobility decreased, X-ray
Clinical narrative: On 04/30/08, my primary care physician said I would benefit by getting the Pneumococcal Vaccine due to my Diabetes.  At that time I had no known allergies.  The evening I around the injection site was a nickle sized raised red bump.  The next morning it was the size of a fifty cent piece,red and warm to touch.  Bump was circled with pen to see if it would spread.  The morning after it had spread,became very painful,started to swell and arm could hardly be raised above my head.  Was taken to Emergency Room and was admitted with cellulitis of L-Arm.  I was hospitalized from 05/02/08 to 05/06/08. 7/1/08-records received for DOS 5/2-5/6/08-DC DX cellulitis left arm.presented with C/O swelling, redness induration and pain after receiving pneumonia vaccine on 4/30/08-PE:erythematous area indurated, warm, swollen tender to palpation.
Age: 8.0
Sex: M
Vaccine: FLU3, HEPA
Symptoms: Erythema, Eyelid oedema, Pruritus, Rash
Clinical narrative: Vaccines given on 3/18/08 with no problems.  Mother brought child back to the health dept on 3/19/08 because child awakened with itching & redness on face with swollen eye lids.  Rash on no other part of body.  Mother gave benadryl at home with no improvement.
Age: 4.0
Sex: F
Vaccine: DTAP, MMR, VARCEL
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: immunization reaction  ldt red hot swollen , 3 days, use ice pack and otc bendryl, rtc if pain or swelling persists
Age: 34.0
Sex: F
Vaccine: PPV, TDAP
Symptoms: Anorexia, Injection site discolouration, Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: PT WOKE UP THE NEXT NEXT DAY C/O BODY ACHES, INJECTION SITE WAS LARGE, RED, WARM TO TOUCH, AND BLACK.  PT ALSO C/O NAUSEA, LOSS OF APPETITE, WHOLE ARM WAS SWOLLEN.PT TOOK TYLENOL & MOTRIN.  SEEN AT ER MONDAY AM, REFERRED TO GENERAL SURGEON TO HAVE ARM DRAINED.
Age: 34.0
Sex: F
Vaccine: PPV, TDAP
Symptoms: Nausea, Oedema peripheral, Pain
Clinical narrative: PT WOKE UP THE NEXT NEXT DAY C/O BODY ACHES, INJECTION SITE WAS LARGE, RED, WARM TO TOUCH, AND BLACK.  PT ALSO C/O NAUSEA, LOSS OF APPETITE, WHOLE ARM WAS SWOLLEN.PT TOOK TYLENOL & MOTRIN.  SEEN AT ER MONDAY AM, REFERRED TO GENERAL SURGEON TO HAVE ARM DRAINED.
Age: 11.0
Sex: F
Vaccine: MNQ
Symptoms: Consciousness fluctuating, Dizziness, Heart rate normal
Clinical narrative: Department of Health mass immunization clinic at elementary and high school to provide meningococcal vaccine in a large group setting.  Patient received vaccination at 10:00 am was monitored in the same area for 20 minutes post vaccination.  Patient went back to class.  Teacher called school nurse up to room at 11:00 am. Stating child was light headed.  School nurse immediately call 911 and brought child back to immunization area in stretcher/chair.  VS: Pulse 68.  Patient semi in and out of conscious.  Ambulance arrive. Parent called by school nurse.  School nurse escorted child in ambulance and transported to hospital. Pt same day transfered to another Hospital. 6/24/08-records received for DOS 4/30/08-C/O pain in right upper arm after vaccine. Dizziness when standing up after vaccine. Some weakness in legs. While at school pushed by another student and had mild bump on head no LOC. PE:WNL, upper extremity (R) at injection site mild edema, tenderness. Neuro exam WNL. Assessment:probably reaction to injection now fine
Age: 14.0
Sex: F
Vaccine: HPV4, TDAP
Symptoms: Cellulitis
Clinical narrative: Pt developed small 4 cm cellulitis in left arm
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Convulsion, Syncope
Clinical narrative: patient was standing in hall and had seizure activity with syncoable episode
Age: 25.0
Sex: F
Vaccine: TD
Symptoms: Urticaria
Clinical narrative: Urticaria 14 hours after administration Td Adsorbed vaccine. Had Salmon and Almonds for dinner 2 hours before symptons began. Seen at ER Anthistamine and Dexametasone were administered with good results, sent home with oral Anthistamine and Prednisone.
Age: 23.0
Sex: M
Vaccine: ANTH
Symptoms: Skin lesion, Swelling
Clinical narrative: pt given anthrax vaccine 02 Jun 08 left deltoid SQ.  pt started experiencing an swelling and an outbreak of lesions on his lower face and neck on 05 Jun 08.  pt went to ER 08Jun08.  pt was Rx benadryl, cleocin, and bacitracin.  Pt was seen at Clinic 09 Jun 08.  Dr. referred pt to Allergy clinic.
Age: 14.0
Sex: F
Vaccine: DT, HPV4
Symptoms: Erythema, Injection site irritation, Injection site pain, Injection site swelling
Clinical narrative: Irritation, swelling, pain to injection site left deltoid area duration 2 days today slight erythema
Age: 1.08
Sex: M
Vaccine: MMR
Symptoms: Pyrexia, Rash
Clinical narrative: 13 month old with rash to face, trunk and fever.  Given Veadryl, Motrin, Tylenol
Age: 4.0
Sex: M
Vaccine: DTAP, HEPA, IPV, MMR, VARCEL
Symptoms: Rash pruritic
Clinical narrative: 06/06/2008 Developed, itcy rash on right leg and stomach.  Saw Physician, placed on antibotic, rash completely gone(per mom) 06/07/2008.  Patients mom denies other signs or symptoms.
Age: 0.44
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Abdominal mass, Abdominal pain, Barium double contrast, Dehydration, Fatigue
Clinical narrative: Patient was given vaccine on 6/5/08.  Mother and father brought in child to ED on 6/7/08 for concerns of 5 days of tactile fevers (reportedly before vaccine was given, unknown to MD), 2 days of emesis after feeds, abdominal pain, and one episode of bloody stool.  At ED, MD noted multiple bilious emesis, abdominal pain, bloody mass in rectum, and palpated a "sausage-shaped" RLQ mass; patient was also noted to look tired and dehydrated with decrease in urine output, but had no other symptoms.  Patient was found to have an ileocolic intussusception upon fluoroscopy and air contrast enema, and was reduced.  After over 24 hours of observation and on Flagyl and Rocephin, patient has not had recurrence of symptoms and is tolerating bottle formula, doing well.  It is unclear that patient's intussusception was due to Rotavirus vaccine administration, as patient was febrile prior to administration.  08/08/2008 MR received for DOD 6/7-9/2008 with D/C DX: Intussusception.  Pt seen in ER for fever and vomiting 1 day prior to vax admin.  Returned 6/7/08 twice with fever and vomiting and inability to maintain po intake. With 2nd visit new onset of bloody stool. Dx with gastroenteritis and again D/c home. Later requested to return to hospital with concern for Intussusception. Pt had continued to vomit multiple times now bilious and green. On PE a sausage shaped abd mass noted. Transfered to higher level of care. Upon arrival US confirmed IS, NG tube placed and pt given barium enema which was successful at reduction. did well post procedure and d/c home next day.
Age: 0.44
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Haematochezia, Intussusception, Rectal haemorrhage, Ultrasound abdomen abnormal, Urinary system X-ray
Clinical narrative: Patient was given vaccine on 6/5/08.  Mother and father brought in child to ED on 6/7/08 for concerns of 5 days of tactile fevers (reportedly before vaccine was given, unknown to MD), 2 days of emesis after feeds, abdominal pain, and one episode of bloody stool.  At ED, MD noted multiple bilious emesis, abdominal pain, bloody mass in rectum, and palpated a "sausage-shaped" RLQ mass; patient was also noted to look tired and dehydrated with decrease in urine output, but had no other symptoms.  Patient was found to have an ileocolic intussusception upon fluoroscopy and air contrast enema, and was reduced.  After over 24 hours of observation and on Flagyl and Rocephin, patient has not had recurrence of symptoms and is tolerating bottle formula, doing well.  It is unclear that patient's intussusception was due to Rotavirus vaccine administration, as patient was febrile prior to administration.  08/08/2008 MR received for DOD 6/7-9/2008 with D/C DX: Intussusception.  Pt seen in ER for fever and vomiting 1 day prior to vax admin.  Returned 6/7/08 twice with fever and vomiting and inability to maintain po intake. With 2nd visit new onset of bloody stool. Dx with gastroenteritis and again D/c home. Later requested to return to hospital with concern for Intussusception. Pt had continued to vomit multiple times now bilious and green. On PE a sausage shaped abd mass noted. Transfered to higher level of care. Upon arrival US confirmed IS, NG tube placed and pt given barium enema which was successful at reduction. did well post procedure and d/c home next day.
Age: 0.44
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Urine output decreased, Vomiting, X-ray abnormal
Clinical narrative: Patient was given vaccine on 6/5/08.  Mother and father brought in child to ED on 6/7/08 for concerns of 5 days of tactile fevers (reportedly before vaccine was given, unknown to MD), 2 days of emesis after feeds, abdominal pain, and one episode of bloody stool.  At ED, MD noted multiple bilious emesis, abdominal pain, bloody mass in rectum, and palpated a "sausage-shaped" RLQ mass; patient was also noted to look tired and dehydrated with decrease in urine output, but had no other symptoms.  Patient was found to have an ileocolic intussusception upon fluoroscopy and air contrast enema, and was reduced.  After over 24 hours of observation and on Flagyl and Rocephin, patient has not had recurrence of symptoms and is tolerating bottle formula, doing well.  It is unclear that patient's intussusception was due to Rotavirus vaccine administration, as patient was febrile prior to administration.  08/08/2008 MR received for DOD 6/7-9/2008 with D/C DX: Intussusception.  Pt seen in ER for fever and vomiting 1 day prior to vax admin.  Returned 6/7/08 twice with fever and vomiting and inability to maintain po intake. With 2nd visit new onset of bloody stool. Dx with gastroenteritis and again D/c home. Later requested to return to hospital with concern for Intussusception. Pt had continued to vomit multiple times now bilious and green. On PE a sausage shaped abd mass noted. Transfered to higher level of care. Upon arrival US confirmed IS, NG tube placed and pt given barium enema which was successful at reduction. did well post procedure and d/c home next day.
Sex: U
Vaccine: MMR, VARCEL
Symptoms: Injection site erythema, Urticaria
Clinical narrative: hives lasting one day with persistant erythema at site of VZV vaccine
Age: 17.0
Sex: M
Vaccine: HEPA
Symptoms: Urticaria
Clinical narrative: patient delevoped hives within 20 minutes of vaccine administration. went to pcp for follow up.pt also received immune globulin hep a at the same time.
Age: 72.0
Sex: M
Vaccine: FLU3
Symptoms: Pain, Pain in extremity, Paraesthesia, Syncope
Clinical narrative: According to the client, on 11/2/07 he received  flu vaccine IM.  11/4/07, hands began tingling.  After a few days, arms and legs were ached and on 11/13/07 he fainted.  He was taken to the local ER and was transferred to another hospital where he stayed for 5 weeks. He was then transferred to Rehab Unit and had therapy for 3 months. 6/30/08-records received for DOS 11/14-12/6/07-DC DX:Acute infective polyneuritis. Pneumonia due to Streptococcus, panic disorder with agoraphobia. Transferred to rehab. Presented with paresthesias in hands a few days after vaccination and 1 week later on 11/12/07-began having weakness in legs and subsequently fell and has been unable to walk. Arms weak. Neuro exam, general weakness, no fasciculations. HX of diarrhea several days prior to onset of symptoms. Treated with IVIG.  8/5/08-records received for DOS 12/6/07-01/08/08-DC DX: Guillain Barre syndrome with paralysis from neck down with improvement. Involvement of upper and lower extremities and swallowing early on, at time of discharge slight movement of upper extremities and lower extremities.
Age: 14.0
Sex: F
Vaccine: HPV4
Symptoms: Dizziness, Feeling cold
Clinical narrative: Patient reported her throat was 'cool" and her left arm felt cool, also.  She felt "light-headed" five minutes after vaccination.  Dr. assessed patinet lying down in exam room.  Dr. reported that patient spoke without difficulty, no swelling or edema, no wheezing.  VS - WNL.  Patient consented to lay down for 20 minutes, then sat in chair for 10 minutes, left with her mother without having any additional problems.
Age: 17.0
Sex: M
Vaccine: MNQ, TDAP, VARCEL
Symptoms: Fall, Syncope
Clinical narrative: PATIENT HAD NOT HAD ANYTHING TO EAT THAT MORNING AND WAS NERVOUS ABOUT THE SHOTS. HE RECIEVED HIS SHOTS AROUND 11:15 AM THAT MORNING OF TDAP, MCV4, VARICELLA AND A TB TEST. RIGHT AFTER RECIEVING HIS SHOTS HE GOT UP FROM THE CHAIR AND FOLLOWED HIS MOM TO THE CASHIER WINDOW AND FAINTED AND FELL BACK ON TO THE FLOOR HITTING THE BACK OF HIS HEAD. THERE WAS NO INJURY TO HIS HEAD.HE CAME TO RIGHT AWAY AND WE HAD HIM LAY THERE FOR ABOURT 5 MINUTES TILL HE FELT BETTER, THEN WE WALKED HIM BACK TO THE ROOM WHERE WE HAD HIM WAIT FOR ABOUT 20 MINUTES. HE SAID HE FELT FINE AND WAS READY TO LEAVE.DURING THE WAIT WE FED HIM SOME CRACKERS AND DR.PEPPER. PATIENT WAS BROUGHT BACK FOR A TB READING ON MONDAY 06/09/08 TWO DAYS LATER, ( THE INCIDENT HAPPENED ON 06/07/08 SATURDAY).MOM CLAIMS THAT HE WAS FINE FOR THE REST OF THAT SATURDAY 06/07/08 AND HAS HAD NO PROBLEMS.
Age: 16.0
Sex: U
Vaccine: TYP
Symptoms: Chills, Headache, Pyrexia, Vaccine positive rechallenge, Vomiting
Clinical narrative: Patient took one dose of oral typhoid and began to experience headaches and fever.  Two days later, when he took the second dose, he again had headaches and fever up to 101 degrees, with chills.  He vomited as well.
Age: 10.0
Sex: M
Vaccine: HEPA, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site swelling, Local reaction
Clinical narrative: DAY AFTER VZV WAS GIVEN TO PATIENT IN RT ARM SQ REDNESS,SWELLING AND PAIN NOTED AT SITE BY MOM ON DAY 2 POST VACCINE THE AREA OF REDNESS WAS SPREADING AND STILL PAINFUL. PATEINT WAS SEEN ON 6/6/08 VACCINE GIVEN ON 6/4/08. DIAGNOSED WITH LOCALIZED REACTION AT INJECTINON SITE BY NP. TREATMENT OF COOL COMPRESSES, TYLENOL PRN AND TO RETURN TO OFFICE FOR INCREASE IN REDNESS OF FURTHER CONCERNS.
Age: 26.0
Sex: M
Vaccine: ANTH
Symptoms: Rash
Clinical narrative: Pt states he exeperienced a rash on foot after receiving the anthrax vaccination.  This complaint is from an injection patient received a year ago. Patient was due for an anthrax booster 8 june 2008 and that is when he brought up concerns from prior injection.
Age: 21.0
Sex: M
Vaccine: SMALL
Symptoms: Blood creatine phosphokinase MB increased, Blood creatine phosphokinase increased, Blood pressure, Chest pain, Dyspnoea
Clinical narrative: 21 YO PATIENT PRESENTED WITH SEVERE MIDSTERNAL CHEST PAIN. SYMPTOMS STARTED THE PRIOR DAY. HE AWOKE AT 5AM WITH 10/10 PAIN AND SOME DYSPNEA. HE REOPORTED "FLU" SYMPTOMS 48 HOURS PRIOR TO HIS PRESENTATION. IN ADDITION HE WAS FEBRILE ON INITIAL PRESENTATION. HE PRESENTED TO MEDICAL AND WITH HTN BP 150/101. EKG REVEALED DIFFUSE ST-T CHANGES AND POSSIBLE OLD IWMI. CARDIAC MARKERS; TROPONIN AND CK-MB WERE POSITIVE. U/S REVEALED PRESERVED LV FXN NO WALL MOTION CHANGES. PT WAS TREATED FOR HTN AND POSSIBLE ISCHEMIC EVENT. NO LMWH WAS GIVEN AS MYOPERICARDITIS WAS HIGH ON DIFFERENTIAL. PT ADMITTED REMAINED STABLE HEMODYNAMICALLY IN ICU. MEDEVACED TO MC WHERE DX OF MYOPERICARDITIS WAS CONFIRMED. PT RECEIVED SMALLPOX VACCINATION 26MAY08.  7/15/08 Reviewed medical records of 6/5-6/6/2008. FINAL DX: NSTEMI; myopericarditis; HTN Records reveal patient experienced awakening w/substernal chest pain x 1 day.  Had fever, malaise, muscle aches s/p anthrax vaccination w/night sweats x 2 days. Transferred to higher level of care.
Age: 21.0
Sex: M
Vaccine: SMALL
Symptoms: Electrocardiogram ST segment elevation, Electrocardiogram abnormal, Hypertension, Influenza like illness, Myopericarditis
Clinical narrative: 21 YO PATIENT PRESENTED WITH SEVERE MIDSTERNAL CHEST PAIN. SYMPTOMS STARTED THE PRIOR DAY. HE AWOKE AT 5AM WITH 10/10 PAIN AND SOME DYSPNEA. HE REOPORTED "FLU" SYMPTOMS 48 HOURS PRIOR TO HIS PRESENTATION. IN ADDITION HE WAS FEBRILE ON INITIAL PRESENTATION. HE PRESENTED TO MEDICAL AND WITH HTN BP 150/101. EKG REVEALED DIFFUSE ST-T CHANGES AND POSSIBLE OLD IWMI. CARDIAC MARKERS; TROPONIN AND CK-MB WERE POSITIVE. U/S REVEALED PRESERVED LV FXN NO WALL MOTION CHANGES. PT WAS TREATED FOR HTN AND POSSIBLE ISCHEMIC EVENT. NO LMWH WAS GIVEN AS MYOPERICARDITIS WAS HIGH ON DIFFERENTIAL. PT ADMITTED REMAINED STABLE HEMODYNAMICALLY IN ICU. MEDEVACED TO MC WHERE DX OF MYOPERICARDITIS WAS CONFIRMED. PT RECEIVED SMALLPOX VACCINATION 26MAY08.  7/15/08 Reviewed medical records of 6/5-6/6/2008. FINAL DX: NSTEMI; myopericarditis; HTN Records reveal patient experienced awakening w/substernal chest pain x 1 day.  Had fever, malaise, muscle aches s/p anthrax vaccination w/night sweats x 2 days. Transferred to higher level of care.
Age: 21.0
Sex: M
Vaccine: SMALL
Symptoms: Pain, Pyrexia, Troponin increased
Clinical narrative: 21 YO PATIENT PRESENTED WITH SEVERE MIDSTERNAL CHEST PAIN. SYMPTOMS STARTED THE PRIOR DAY. HE AWOKE AT 5AM WITH 10/10 PAIN AND SOME DYSPNEA. HE REOPORTED "FLU" SYMPTOMS 48 HOURS PRIOR TO HIS PRESENTATION. IN ADDITION HE WAS FEBRILE ON INITIAL PRESENTATION. HE PRESENTED TO MEDICAL AND WITH HTN BP 150/101. EKG REVEALED DIFFUSE ST-T CHANGES AND POSSIBLE OLD IWMI. CARDIAC MARKERS; TROPONIN AND CK-MB WERE POSITIVE. U/S REVEALED PRESERVED LV FXN NO WALL MOTION CHANGES. PT WAS TREATED FOR HTN AND POSSIBLE ISCHEMIC EVENT. NO LMWH WAS GIVEN AS MYOPERICARDITIS WAS HIGH ON DIFFERENTIAL. PT ADMITTED REMAINED STABLE HEMODYNAMICALLY IN ICU. MEDEVACED TO MC WHERE DX OF MYOPERICARDITIS WAS CONFIRMED. PT RECEIVED SMALLPOX VACCINATION 26MAY08.  7/15/08 Reviewed medical records of 6/5-6/6/2008. FINAL DX: NSTEMI; myopericarditis; HTN Records reveal patient experienced awakening w/substernal chest pain x 1 day.  Had fever, malaise, muscle aches s/p anthrax vaccination w/night sweats x 2 days. Transferred to higher level of care.
Age: 16.0
Sex: F
Vaccine: MNQ, VARCEL
Symptoms: Chills, Headache, Malaise, Pyrexia
Clinical narrative: Mother called and reported chills, fever headache & malaise.
Age: 49.0
Sex: F
Vaccine: TDAP
Symptoms: Hypoaesthesia, Muscle spasms, Myalgia, Nausea, Pyrexia
Clinical narrative: Client reports a few hrs after receiving vaccine. She began with severe muscle aches, spasms, n&V, fever and numbness of the hands approx x 12 hrs.
Age: 49.0
Sex: F
Vaccine: TDAP
Symptoms: Vomiting
Clinical narrative: Client reports a few hrs after receiving vaccine. She began with severe muscle aches, spasms, n&V, fever and numbness of the hands approx x 12 hrs.
Age: 65.0
Sex: F
Vaccine: FLU3, VARZOS
Symptoms: Back pain, Chest pain, Injected limb mobility decreased, Pain in extremity
Clinical narrative: Few hours after vaccines, pt's (R) arm became very painful. Pain also wrapped around chest/back. Pt unable to move arm 2 degrees. Pain began to resolve in < 24 hrs and completely symptom free within one week.
Age: 84.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Lethargy, Oxygen saturation decreased, Tachycardia, Tremor
Clinical narrative: Acute onset tachycardia, lethargy tremulous.  Decreased O2 sat, sent to ER via 911.  8/5/08 Reviewed hospital medical records of 5/21/08. FINAL DX: allergic reaction & UTI Records reveal patient experienced shaking & chills, increased BP & pulse, SOB.  Had temp of 99 in ER, P 102, R 22, BP 188/91.  Tx w/IV antihistamine.  D/C to home on oral antibiotic.  8/15/08 Reviewed PCP med records of 5/21-5/28/08. FINAL DX: none provided Records reveal patient experienced tremors, tachycardia & HTN on 5/21 & was sent to ER.  On 5/27 reported episodes of lightheadedness, weakness, tachycardia & feeling faint daily since vaccination.  Referred for Holter monitor.
Age: 84.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Fatigue, Hypertension, Immediate post-injection reaction, Nausea, Tachycardia
Clinical narrative: Acute onset tachycardia, lethargy tremulous.  Decreased O2 sat, sent to ER via 911.  8/5/08 Reviewed hospital medical records of 5/21/08. FINAL DX: allergic reaction & UTI Records reveal patient experienced shaking & chills, increased BP & pulse, SOB.  Had temp of 99 in ER, P 102, R 22, BP 188/91.  Tx w/IV antihistamine.  D/C to home on oral antibiotic.  8/15/08 Reviewed PCP med records of 5/21-5/28/08. FINAL DX: none provided Records reveal patient experienced tremors, tachycardia & HTN on 5/21 & was sent to ER.  On 5/27 reported episodes of lightheadedness, weakness, tachycardia & feeling faint daily since vaccination.  Referred for Holter monitor.
Age: 84.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Tremor
Clinical narrative: Acute onset tachycardia, lethargy tremulous.  Decreased O2 sat, sent to ER via 911.  8/5/08 Reviewed hospital medical records of 5/21/08. FINAL DX: allergic reaction & UTI Records reveal patient experienced shaking & chills, increased BP & pulse, SOB.  Had temp of 99 in ER, P 102, R 22, BP 188/91.  Tx w/IV antihistamine.  D/C to home on oral antibiotic.  8/15/08 Reviewed PCP med records of 5/21-5/28/08. FINAL DX: none provided Records reveal patient experienced tremors, tachycardia & HTN on 5/21 & was sent to ER.  On 5/27 reported episodes of lightheadedness, weakness, tachycardia & feeling faint daily since vaccination.  Referred for Holter monitor.
Age: 65.0
Sex: F
Vaccine: TDAP
Symptoms: Erythema, Injection site erythema, Injection site pain, Injection site warmth, Skin warm
Clinical narrative: Tdap on May 14. Symptoms of redness of the injection site on 5/20/08. Also warmth and tenderness. Also another similar area on the neck on the same side as injection.
Age: 65.0
Sex: F
Vaccine: TDAP
Symptoms: Tenderness
Clinical narrative: Tdap on May 14. Symptoms of redness of the injection site on 5/20/08. Also warmth and tenderness. Also another similar area on the neck on the same side as injection.
Age: 63.0
Sex: F
Vaccine: TDAP
Symptoms: Cough, Wheezing
Clinical narrative: Deep cough with wheezing; violent coughing; fever; poss pneumonia; wheezing; difficulty breathing, hoarseness. I required antibiotics prescribed by my PCP (5-day course for Pertussis)
Age: 0.17
Sex: F
Vaccine: DTAP, HIBV, IPV, PNC, RV5
Symptoms: Crying, Screaming
Clinical narrative: Baby screamed/cried for three hours.
Age: 18.0
Sex: F
Vaccine: HPV4, MNQ
Symptoms: Pruritus, Rash
Clinical narrative: Pt reported to school health office 1:45 pm, 5/16/08, 3h after iz, with rash on (L) arm - HPV side. 3 areas on arm, 1 the size of a silver dollar, 2" below injection site. 2 smaller spots near elbow, each 1cm in size; Tx with itch relief; parent contacted. Observed for 40 min; sent home; f/u 5/19: no hives; patient reported they resolved after 4 hours.
Age: 28.0
Sex: F
Vaccine: TDAP
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Swelling, pain, and redness to vaccine site.  Started PM of 6-3-08.  KEFLEX and BENADRYL.
Age: 24.0
Sex: F
Vaccine: HEP, HEPA, IPV, MMR, TDAP, VARCEL
Symptoms: Ecchymosis, Oedema peripheral
Clinical narrative: Localized edema and ecchymosis (mild) over posterior aspect of right upper arm. Pt assessed 3 days following vaccine administration. Patient treated with NSAID and antiemetic, advised to follow up if symptoms worsen.
Age: 12.0
Sex: F
Vaccine: HPV4, MNQ
Symptoms: Blood pressure, Dizziness, Heart rate normal, Immediate post-injection reaction, Nausea
Clinical narrative: Child nauseated, lightheaded, dizzy immediately after injection.  Needed to lie down for 30 min.  Eventually recovered with no other effects.
Age: 12.0
Sex: F
Vaccine: HPV4, MNQ
Symptoms: Oxygen saturation decreased
Clinical narrative: Child nauseated, lightheaded, dizzy immediately after injection.  Needed to lie down for 30 min.  Eventually recovered with no other effects.
Age: 60.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema
Clinical narrative: 35mm reddened area LD arm SC noted no pain or hot to touch.
Age: 19.0
Sex: F
Vaccine: HPV4
Symptoms: Blood pressure, Cold sweat, Disturbance in attention, Dizziness, Feeling cold
Clinical narrative: 6-3-08 pt. received HPV #1, L delt. via biojector at 2:30 pm.  2:45 pm pt. became pale lightheaded & unable to concentrate.  Placed head between legs .  At 3 pm given juice, cool cloth to head & laid her back in chair.  Approx 3:15 diaphoretic, P 71, BP 120/76.  3:30 pm ambulated to bathroom became lightheaded again.  Laid back down cold clammy, diaphoretic, pale.  4 pm pt. states she felt better.  Color pink, skin warm to touch.
Age: 19.0
Sex: F
Vaccine: HPV4
Symptoms: Heart rate normal, Hyperhidrosis, Pallor
Clinical narrative: 6-3-08 pt. received HPV #1, L delt. via biojector at 2:30 pm.  2:45 pm pt. became pale lightheaded & unable to concentrate.  Placed head between legs .  At 3 pm given juice, cool cloth to head & laid her back in chair.  Approx 3:15 diaphoretic, P 71, BP 120/76.  3:30 pm ambulated to bathroom became lightheaded again.  Laid back down cold clammy, diaphoretic, pale.  4 pm pt. states she felt better.  Color pink, skin warm to touch.
Age: 23.0
Sex: F
Vaccine: YF
Symptoms: Erythema, Induration, Skin warm
Clinical narrative: Came in 7 days after administration of yellow fever vaccine, for evaluation of large (~3.5 cm) area of erythema, warmth, mild induration.  Was put on KEFLEX 500mg tid for possible cellulitis.
Age: 66.0
Sex: F
Vaccine: VARZOS
Symptoms: Blister
Clinical narrative: Tiny, blister like "pimple" 4" below injection site. Not itchy. No pain, swelling or itching at inj. site. Appeared 4 days after IZ. Feels well otherwise.
Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: C-reactive protein decreased, Polyarthritis, Rash, Red blood cell sedimentation rate increased, Serum sickness
Clinical narrative: Inflammatory arthritis, diffuse rash, probably serum sickness.
Age: 0.61
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Culture stool, Enteritis, Off label use
Clinical narrative: After off the label use of Rotavirus vaccine #1 on 4/14/08, patient developed acute enteritis for about 7-8 days - seen at ER (Rotavirus vaccine was not ordered by MD)
Age: 10.0
Sex: M
Vaccine: HEPA, TDAP
Symptoms: Erythema, Feeling hot, Local swelling, Pyrexia
Clinical narrative: Dark, red, warm, swollen area localized over left deltoid area.  Low grade fevers.  Visited ER, urgent care, and pediatrician for follow-up 4 times during week after onset of reaction.
Age: 0.3
Sex: F
Vaccine: DTP, HIBV, IPV, PNC, RV5
Symptoms: Dyspnoea, Irritability, Urticaria, Vomiting
Clinical narrative: Within 48 hours patient had hives, irritability, vomiting & difficulty breathing.  Was taken to ER.  Kept for observation & breathing challenges for 8 hrs.
Age: 21.0
Sex: F
Vaccine: HPV4
Symptoms: Computerised tomogram abnormal, Concussion, Head injury, Loss of consciousness, Skull fractured base
Clinical narrative: 3/10/08, patient was given her 2nd GARDASIL vaccine, initially tolerated well.  She was standing at the checkout area approximately 10 minutes after injection and passed out hitting her head on counter.  She had a concussion, was sent to ER.  While in ER CT scan which revealed 2 hair line fractures of occipital bone.
Age: 11.0
Sex: F
Vaccine: TDAP, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site pruritus, Injection site swelling, Nausea
Clinical narrative: Nausea, dry heaves, paleness, fever, swelling shoulder to elbow with redness and tenderness - seen 6-4-08 - swelling below elbow.  Benadryl - warm compresses - Prednisone. Follow-up Information 01-JUL-2008: Received steroids starting 6-4-08. Mother stated by the 2nd day of steroids was back to normal. However, on 6-13-08 mom called stating the site was itching again with long red streak that was not raised. Mom found out that child had not completed her steroid treatment and would finish it. Was to call if any further problems. As of 6-27-08 no further problems.
Age: 11.0
Sex: F
Vaccine: TDAP, VARCEL
Symptoms: Oedema peripheral, Pallor, Pyrexia, Retching
Clinical narrative: Nausea, dry heaves, paleness, fever, swelling shoulder to elbow with redness and tenderness - seen 6-4-08 - swelling below elbow.  Benadryl - warm compresses - Prednisone. Follow-up Information 01-JUL-2008: Received steroids starting 6-4-08. Mother stated by the 2nd day of steroids was back to normal. However, on 6-13-08 mom called stating the site was itching again with long red streak that was not raised. Mom found out that child had not completed her steroid treatment and would finish it. Was to call if any further problems. As of 6-27-08 no further problems.
Age: 28.0
Sex: F
Vaccine: HEPAB, MMR, TDAP, VARCEL
Symptoms: Drug exposure during pregnancy, Inappropriate schedule of drug administration, Pregnancy test positive
Clinical narrative: Client denying pregnancy at time of vaccination discovered she was pregnant 10 days later.  Client notified of the obstetrical risks placed on varicella in pregnancy registry.  Client has follow-up maternity appointment with the gynecologist.
Age: 16.0
Sex: M
Vaccine: HEPA, MNQ, TDAP
Symptoms: Asthenia, Dizziness, Syncope
Clinical narrative: Patient complained of dizziness, felt weak - was being assisted back to a room, went down to floor on his knees and fainted.  Laid patient on bed in room, was awake by this time.  Patient became coherent and oriented x 3.  Face was washed with wet towels and feet elevated.  Provider in room checking patient.  Patient states he had not ate this morning.
Age: 12.0
Sex: F
Vaccine: HPV4
Symptoms: Chest X-ray normal, Chills, Full blood count normal, Laboratory test normal, Pyrexia
Clinical narrative: Fever: 0100AM Chills: 0100AM - Temp 103.6 oral; Taken to ER at 0230. While in ER was given; Two bags of IV fluids. Motrin 400mg and Zofram 2mg
Age: 12.0
Sex: F
Vaccine: HPV4
Symptoms: Streptococcal identification test negative, Urine analysis normal
Clinical narrative: Fever: 0100AM Chills: 0100AM - Temp 103.6 oral; Taken to ER at 0230. While in ER was given; Two bags of IV fluids. Motrin 400mg and Zofram 2mg
Age: 13.0
Sex: F
Vaccine: HPV4
Symptoms: Abdominal pain, Body temperature increased, Fatigue, Headache, Hypersensitivity
Clinical narrative: 3rd GARDASIL injection given at 8:15.  Went home with baby sitter.  Felt fine.  Laid down @ 2:45 and woke up @ 3-3:15.  Complained of severe abdominal pain, pain in injection site and H/A.  Temperature 101 F.  Baby sitter gave 2 Tylenol.  Fever went down.  At 7:30 rash on face, temperature of 99.9.  Saw doctor.  Had sinus drainage.  Was given teaspoon Zantac and 2 Tylenol.  6/4/08, still has rash.  Feels tired.
Age: 13.0
Sex: F
Vaccine: HPV4
Symptoms: Injection site pain, Rash, Sinus congestion
Clinical narrative: 3rd GARDASIL injection given at 8:15.  Went home with baby sitter.  Felt fine.  Laid down @ 2:45 and woke up @ 3-3:15.  Complained of severe abdominal pain, pain in injection site and H/A.  Temperature 101 F.  Baby sitter gave 2 Tylenol.  Fever went down.  At 7:30 rash on face, temperature of 99.9.  Saw doctor.  Had sinus drainage.  Was given teaspoon Zantac and 2 Tylenol.  6/4/08, still has rash.  Feels tired.
Age: 39.0
Sex: F
Vaccine: TDAP
Symptoms: Immediate post-injection reaction, Pain in extremity
Clinical narrative: L deltoid pain immediately after vaccine & persisting for >2wk.  Required (per pt) urgent care visit.
Age: 13.0
Sex: M
Vaccine: TDAP
Symptoms: Dizziness, Fall, Gaze palsy, Loss of consciousness, Muscle rigidity
Clinical narrative: Pt rec'd Tdap injection at approx 4:50 pm and approx 5-10 minutes later he was standing, felt "light-headed" and then had LOC.  No head trauma as he was caught during fall.  While he had LOC -> his eyes were "rolled back" and he felt "rigid".  Pt awoke within a few seconds and was well-oriented, talking normally.  No loss of bowel/bladder.  VS normal after LOC.  Rested, drank juice and d/c home by 5:20 PM.
Age: 47.0
Sex: F
Vaccine: TDAP
Symptoms: Erythema, Oedema peripheral
Clinical narrative: Symptoms appeared yesterday on right shoulder/deltoid with redness and swelling.
Age: 18.0
Sex: F
Vaccine: HPV4, VARCEL
Symptoms: Amnesia, Loss of consciousness, Musculoskeletal stiffness, Urinary incontinence
Clinical narrative: The patient had just received her immunizations and PPD when she slumped over and lost consciousness.  Her body was stiff (particularly her arms) and she lost bladder.  She became alert after approximately 60 seconds and answered all questions appropriately but does have some amnesia surrounding the event.  We kept her in the office for an additional 30 minutes for monitoring.
Age: 0.6
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Diarrhoea, Vomiting
Clinical narrative: 4/26 mom called as vomiting/diarrhea on off since vaccinations.  Started on CULTURELLE 1/2 daily, PEDIALYTE x12 hrs advance slowly.  No fever and good urine output.
Age: 86.0
Sex: M
Vaccine: FLU3
Symptoms: Inappropriate schedule of drug administration
Clinical narrative: Pt had received a flu vaccine on 10/05/07 and was administered a flu vaccine on 12/19/07; pt was in clinic for TST.
Age: 77.0
Sex: F
Vaccine: PPV
Symptoms: Discomfort, Erythema, Oedema peripheral, Pruritus
Clinical narrative: See note enclosed; Patient gave verbal permission; She received a Pneumovax injection yesterday on her left deltoid. It later in the day developed some discomfort, and by this morning. There was redness and swelling. Through the day the redness and swelling has extended down the arm into axilla. There is also itching. There is no fever, chills, or sweats. She is generally pretty healthy, with an elevated cholesterol, history of Graves' disease and osteoporosis.
Age: 10.0
Sex: F
Vaccine: VARCEL
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: Erythema & swelling around injection site of varicella at L upper arm ~3-4 cm.
Age: 57.0
Sex: M
Vaccine: TD
Symptoms: Asthenia, Chills, Pain in extremity, Rash erythematous
Clinical narrative: Approx 12 hrs after Td, L arm pain, weakness, chills - continued to following day.  Fine erythematous rash 2 days after injection.
Age: 45.0
Sex: M
Vaccine: FLU3, PPV, TDAP
Symptoms: Inappropriate schedule of drug administration
Clinical narrative: None.  Given Tdap vaccine.  Not licensed for this age.
Age: 51.0
Sex: M
Vaccine: PPV, TDAP
Symptoms: Wrong drug administered
Clinical narrative: None - given vaccine (TDAP) not licensed for this age.
Age: 57.0
Sex: M
Vaccine: PPV, TDAP
Symptoms: Inappropriate schedule of drug administration
Clinical narrative: None.  Given vaccine (Tdap) not licensed for this age.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Inappropriate schedule of drug administration
Clinical narrative: None given vaccine not licensed for this age.
Age: 53.0
Sex: M
Vaccine: TDAP
Symptoms: Wrong drug administered
Clinical narrative: None give vaccine not licensed for this age.
Age: 44.0
Sex: F
Vaccine: FLU3, TDAP
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling, Oedema peripheral
Clinical narrative: Pt noticed swelling & itching in Lt arm around site of injection 1 day after receiving vaccine.  The swelling & redness have enlarged to include entire upper left arm at 3 days post vaccination.  Pt was referred to MD.
Age: 17.0
Sex: F
Vaccine: HPV4
Symptoms: Blood pressure decreased, Cold sweat, Dizziness, Heart rate decreased, Oxygen saturation decreased
Clinical narrative: Patient got clammy and dizzy with paleness at 1:32PM. At 1:33PM patient fainted. Blood pressure dropped to 80/41, O2 saturation dropped to 89%, Heart rate dropped to 51. Patient recovered after O2. Patient left office with stable vitals with mother at 2:20PM
Age: 17.0
Sex: F
Vaccine: HPV4
Symptoms: Pallor, Syncope
Clinical narrative: Patient got clammy and dizzy with paleness at 1:32PM. At 1:33PM patient fainted. Blood pressure dropped to 80/41, O2 saturation dropped to 89%, Heart rate dropped to 51. Patient recovered after O2. Patient left office with stable vitals with mother at 2:20PM
Age: 82.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site induration, Injection site mass
Clinical narrative: Redness & hard protruding bump at injection site.  Redness is going away per patient.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Swelling and pain/redness started 24 hr. after vaccine at site of injection 6/5/08.  6/6/08-AUGMENTIN/BENADRYL.
Age: 20.0
Sex: M
Vaccine: RAB
Symptoms: Gaze palsy, Snoring
Clinical narrative: After donation donor was in office and received IMOVAX Rabies vaccine 1ml right deltoid. After injection donor dropped chin down, eyes rolled backwards and made snoring noise. Donor responded to voice in 10 sec. Donor did not fall. Donor moved to bed. Office. Vital signs taken; VAERS and DAE-A filled out. H2O and snack given donor recovered in 17min. Left center.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: Patient received vaccines on 6/5/08 (IPV #4, DTaP #5, MMR #2, Varivax #2). Mother noted significant redness, swelling and heat to left inferior thigh the next morning. Patient was seen on 6/7/08 and prescribed antihistamines (oral) as symptomatic treatment.
Age: 1.5
Sex: M
Vaccine: DTAP, IPV
Symptoms: Abnormal behaviour, Aggression, Anorexia, Chills, Heart rate increased
Clinical narrative: 1) high fever -> 24 hours (reduced via TYLENOL + bath) 2) shivering 3) unusual behavior -> 48+ hours 4) fast heart beat -> 12+ hours 5) intense sweating -> 12+ hours 6) vomited (1x) 7) low food intake -> no appetite (48+ hours) 8) irritable -> 48+ hours 9) sleeplessness -> 48+ hours 10) temper tantrums -> unusual to my son 48+ hours 11) very fussy -> 48+ hours 12) developed chest cold 6/7-6/9/08.
Age: 1.5
Sex: M
Vaccine: DTAP, IPV
Symptoms: Hyperhidrosis, Insomnia, Irritability, Lower respiratory tract infection, Oral intake reduced
Clinical narrative: 1) high fever -> 24 hours (reduced via TYLENOL + bath) 2) shivering 3) unusual behavior -> 48+ hours 4) fast heart beat -> 12+ hours 5) intense sweating -> 12+ hours 6) vomited (1x) 7) low food intake -> no appetite (48+ hours) 8) irritable -> 48+ hours 9) sleeplessness -> 48+ hours 10) temper tantrums -> unusual to my son 48+ hours 11) very fussy -> 48+ hours 12) developed chest cold 6/7-6/9/08.
Age: 1.5
Sex: M
Vaccine: DTAP, IPV
Symptoms: Pyrexia, Vomiting
Clinical narrative: 1) high fever -> 24 hours (reduced via TYLENOL + bath) 2) shivering 3) unusual behavior -> 48+ hours 4) fast heart beat -> 12+ hours 5) intense sweating -> 12+ hours 6) vomited (1x) 7) low food intake -> no appetite (48+ hours) 8) irritable -> 48+ hours 9) sleeplessness -> 48+ hours 10) temper tantrums -> unusual to my son 48+ hours 11) very fussy -> 48+ hours 12) developed chest cold 6/7-6/9/08.
Age: 5.0
Sex: M
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site pruritus, Injection site warmth, Pyrexia
Clinical narrative: Patient has temperature and pain in left arm at vaccine site. Red and warm, itchy (scratch marks) to use Tylenol for pain and fever and ice pack to area
Age: 1.2
Sex: F
Vaccine: MMR
Symptoms: Erythema, Pyrexia
Clinical narrative: Fever from 6/1/08; Erythema
Age: 1.5
Sex: F
Vaccine: DTAP, MMR, VARCEL
Symptoms: Injection site erythema, Injection site warmth, Skin tightness
Clinical narrative: 6.5cm area of erythema right lateral thigh skin tight/warm to touch. No drainage/nontender; Treated with Omnicef 125mg/5ml 5ml po qd x10 days
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site cellulitis
Clinical narrative: Right anterolateral thigh 7.5cm local cellulitis at site of injection developed day after immunization mom sought treatment 2 days after immunization. Treatment with Keflex 500mg po qid x10 days
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Blood culture negative, Erythema, Skin plaque, Skin warm, Tenderness
Clinical narrative: Right thigh with 20cm erythematous plaque. Skin warm to touch with some tenderness. No drainage. Treated with Keflex 250mg/5ml po qid x10days; erythema had spread the next day, patient was referred to emergency department
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: White blood cell count normal
Clinical narrative: Right thigh with 20cm erythematous plaque. Skin warm to touch with some tenderness. No drainage. Treated with Keflex 250mg/5ml po qid x10days; erythema had spread the next day, patient was referred to emergency department
Age: 1.5
Sex: F
Vaccine: DTAP, HIBV, MMR
Symptoms: Injection site erythema, Injection site mass, Injection site pain, Injection site warmth
Clinical narrative: (R) thigh at DTaP injection site - 2 in diameter red round area with lump underneath. skin warm to touch/tender. Tx Cefzil 125mg/5ml, 5ml PO BID x 10 days.
Age: 1.6
Sex: F
Vaccine: DTAP, HIBV, IPV, MMR, VARCEL
Symptoms: Autism spectrum disorder, Communication disorder, Developmental delay, Encephalopathy, Irritability
Clinical narrative: This case was received on 26 May 2008 via a search of the scientific literature.  SERIOUSNESS CRITERIA: OTHER - MEDICALLY SIGNIFICANT.  A 19-month-old female patient received the following vaccines: IPV, DTaP, HIB, MMR, and varicella (date of vaccination, manufacturers, route, and site of administration not reported).  Medical history included frequent episodes of fever and otitis media, with bilateral polyethylene tube placement.  At the time of vaccination, the patient was reportedly interactive, playful, and communicative.  Two days after vaccination, she became lethargic, irritable, and febrile.  Ten days after vaccination, she developed a "rash consistent with vaccine-induced varicella".  Months later, she developed neurologic and psychological developmental delays and was diagnosed with encephalopathy caused by a mitochondrial enzyme deficit. Her signs included problems with language, communication, and behavior, noted to be features of autism spectrum disorder.  Outcome was not reported.  No additional information was provided.