Age: 52.0
Sex: F
Vaccine: COVID19
Symptoms: Body mass index, COVID-19, Ecchymosis, Rash vesicular, SARS-CoV-2 test
Clinical narrative: COVID-19 infection; ecchymotic lesion in left thigh, left shoulder and left axilla; small spots on her chest, appearing vesicular; This literature-non-study case was reported in a literature article and describes the occurrence of COVID-19 (COVID-19 infection) in a 52-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.   Concurrent medical conditions included Hypertension.    In 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced COVID-19 (COVID-19 infection) (seriousness criterion hospitalization), ECCHYMOSIS (ecchymotic lesion in left thigh, left shoulder and left axilla) and RASH VESICULAR (small spots on her chest, appearing vesicular). The patient was hospitalized for 2 days due to COVID-19. At the time of the report, COVID-19 (COVID-19 infection), ECCHYMOSIS (ecchymotic lesion in left thigh, left shoulder and left axilla) and RASH VESICULAR (small spots on her chest, appearing vesicular) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Body mass index: 67 pound/inch Square. On an unknown date, SARS-CoV-2 test: (Positive) Positive.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered COVID-19 (COVID-19 infection), ECCHYMOSIS (ecchymotic lesion in left thigh, left shoulder and left axilla) and RASH VESICULAR (small spots on her chest, appearing vesicular) to be related.    No concomitant and treatment information were not provided.  Patient did not have any new medications.  Patient smoking status was reported as no.  Patient experienced COVID-19 related symptoms as Myalgia, fatigue, dizziness.  Patient did not take any birth control medications and patient did not had fever.  COVID-19 cutaneous symptoms described as Left leg bruise followed by skin coming off. Denied any trauma to the area. Looks like left shoulder prior to skin coming off. Pimple like spots on the chest. Another area of skin sloughing in left axilla that hadn't been noticed previously .  Patient did not have any medical history of cancer, skin disorder, myocardial infraction, renal failure, diabetes, cerebrovascular disease/transient ischemic attack, deep vein thrombosis, pulmonary embolism, immunocompromised, vasculitis, autoimmune disorder, immune modulating drugs.  Patient did not require oxygen supplementation but did require supportive care.    First appeared as a purple spot that then darkened, and bubbled at which point the top layer of skin came.  There was another lesion on the left shoulder that had the appearance of the first lesion before the skin sloughing.  No additional treatment was administered for the patient's skin lesions and ecchymotic lesion that had the appearance of the other two lesions in the first stage of their evolution on the left axilla.  Patient reported that there were small spots on chest and appearing vesicular that had arisen after the onset of COVID-19 symptoms.  Company comment: This literature non-study case concerns a 52-year-old female patient, with no relevant medical history, who experienced unexpected, serious (hospitalization) adverse event of special interest Covid19 along with other non-serious events, after receiving a first dose of mRNA-1273.  Since the date of Covid19 infection is unknown, the onset latency in relation to vaccination could not be determined.  She presented with symptoms of myalgia, fatigue, and dizziness.  She also had skin changes described as ecchymotic lesions in the left leg, left shoulder and left axilla, and small vesicular spots on the chest.  She did not have any medical history of prior skin disorders nor skin trauma before Covid19 infection.  The patient was hospitalized for 2 days.  She did not require oxygen supplementation but did require supportive care.  No additional treatment was administered for the patient's skin lesions.  Outcome was unknown.  The ongoing Covid19 pandemic could be contributory factor.  The benefit risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This literature non-study case concerns a 52-year-old female patient, with no relevant medical history, who experienced unexpected, serious (hospitalization) adverse event of special interest Covid19 along with other non-serious events, after receiving a first dose of mRNA-1273.  Since the date of Covid19 infection is unknown, the onset latency in relation to vaccination could not be determined.  She presented with symptoms of myalgia, fatigue, and dizziness.  She also had skin changes described as ecchymotic lesions in the left leg, left shoulder and left axilla, and small vesicular spots on the chest.  She did not have any medical history of prior skin disorders nor skin trauma before Covid19 infection.  The patient was hospitalized for 2 days.  She did not require oxygen supplementation but did require supportive care.  No additional treatment was administered for the patient's skin lesions.  Outcome was unknown.  The ongoing Covid19 pandemic could be contributory factor.  The benefit risk relationship of mRNA-1273 is not affected by this report.