Sex: F
Vaccine: COVID19
Symptoms: Affect lability, Antinuclear antibody positive, Blood glucose, Blood glucose normal, Chest X-ray
Clinical narrative: VISUAL AND AUDITORY HALLUCINATIONS; HYPERACTIVITY; FLIGHT OF IDEAS; EMOTIONAL LABILITY; CIRCUMSTANTIAL SPEECH; TIME SEQUENCING; HYPERSENSITIVITY TO SMELLS; ALTERED MENTAL STATUS; HYPERSENSITIVITY TO SOUND; HYPERSENSITIVITY TO TASTE; HYPERSENSITIVITY TO VISUAL DISPLAYS; CHILLS; FEVER; FATIGUE; This spontaneous report received from a consumer concerned a female of unspecified age. The patient's weight, height, and medical history were not reported. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 1805022, expiry: UNKNOWN) dose was not reported, administered on 19-MAR-2021 approximately at 10:30 am for prophylactic vaccination. No concomitant medications were reported. On 19-MAR-2021, within 6 hours from vaccination, the patient developed fever, chills, fatigue, which she treated with rest and acetaminophen. At 24 hours post vaccine, on 20-MAR-2021, patient experienced  hyperactivity, flight of ideas, emotional lability, and visual and auditory hallucinations. At approximately 50 hours post vaccination, the symptoms worsened and patient was brought to the emergency room on 21-Mar-2021. Hospital Providers found lab work:  CBC (complete blood count), BGM (Blood glucose meter), metabolic panel, urine analysis, EKG (electrocardiogram), chest x-ray, CT (computerized tomography)of the head all to be within normal limits. Patient was admitted to the hospital for altered mental status. On 22-Mar-2021, providers ordered EEG (electroencephalogram )showing irregularity in the temporal lobe, MRI(Magnetic resonance imaging ) of the brain within normal limits, Lumbar puncture negative for bacteria, HSV, normal glucose/protein. ANA blood test positive. Due to persistent psychological symptoms and all medical tests coming back essentially normal, on the 4th day of her hospital stay, patient was admitted to the psychiatric unit for question delirium vs. late onset bipolar disorder. The environment on the psychiatric floor was worsening her symptoms ,and family and hospital providers agreed that she would do better in her home environment and she was discharged on 30-Mar-2021. The patient was hospitalized for 9 days. Initial symptoms greatly improved by 2-Apr-2021, but circumstantial speech (coded as circumstantiality), time sequencing (coded as temporal disorientation), hypersensitivity to smells, hypersensitivity to sounds, hypersensitivity to visual displays (coded as light sensitivity to eye), hypersensitivity to taste was persistent. The reporter was following up outpatient with psychiatry and was in pursuit of a primary care physician. Laboratory data included: Blood glucose (NR: not provided) within normal limits, CBC (NR: not provided) within normal limits, Chest X-ray (NR: not provided) within normal limits, Computerized tomogram head (NR: not provided) within normal limits, EKG (NR: not provided) within normal limits, Metabolic function test (NR: not provided) within normal limits, and Urine analysis (NR: not provided) within normal limits. On 22-MAR-2021, Laboratory data included: Antinuclear antibody positive (NR: not provided) positive, Blood glucose normal (NR: not provided) normal, EEG (NR: not provided) irregularity in the temporal lobe, Herpes simplex (NR: not provided) unknown, Lumbar puncture (NR: not provided) negative for bacteria, MRI brain (NR: not provided) within normal limits, and Protein NOS normal (NR: not provided) normal. Treatment medications (dates unspecified) included: paracetamol. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The outcome of the fever, chills, fatigue, hyperactivity, flight of ideas, emotional lability, visual and auditory hallucinations, circumstantial speech, time sequencing, hypersensitivity to smells, altered mental status, hypersensitivity to sound, hypersensitivity to visual displays and hypersensitivity to taste was not reported. This report was serious (Hospitalization Caused / Prolonged).; Sender's Comments: V0: 20210407369-covid-19 vaccine ad26.cov2.s-Visual and auditory hallucinations, Hyperactivity, flight of ideas, emotional lability, circumastantial speech, time sequencing, hypersensitivity to smell, altered mental status, hypersensitivity to sound, hypersensitivity to taste, hypersensitivity to visual display. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).