Age: 17.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Joint swelling, Metabolic function test, Peripheral swelling, Red blood cell sedimentation rate, Urticaria
Clinical narrative: they are welts and her eyes are swollen shut; her knuckles are swollen; she couldn't walk the other day her toes were swollen; she couldn't walk the other day her toes were swollen/her feet are swollen; incredibly uncomfortable; Hives; This is a spontaneous report from a contactable nurse (patient's mother). A 17-year-old female patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; Batch/Lot Number: Unknown), via an unspecified route of administration, administered in left arm on 11Apr2021 as single dose for COVID-19 immunization. The patient's medical history included autoimmune, gallbladder removed on 30Apr2021, allergy to penicillin and cephalosporin. The patient's concomitant medications included desvenlafaxine succinate (PRISTIQ) and lamotrigine (LAMICTAL). Vaccination facility type was school/student health clinic. Vaccine was not administered at military facility. The patient had no other vaccinations within four weeks prior to the first administration date of the suspect vaccine. On 15Apr2021 (4 days after vaccination), she developed hives so she has had hives ever since then and she was on hefty doses of antihistamines. She was on Allegra 180mg twice a day and Pepcid 20mg twice a day. She was heading into week 7 or 8 with lots of doctor visits and medications and no real answers. The patient's mother reported that they were welts and her eyes were swollen shut on an unspecified date. Her feet were swollen, her knuckles were swollen and she couldn't walk the other day her toes were swollen. The patient's mother reported that she was incredibly uncomfortable. The patient's mother stated that the hives started 15Apr2021 and she would say to her it was medically significant as they have lasted so long and she doesn't have the allergic reaction with wheezing or anaphylaxis. There were there every single day and it takes until late at night to dissipate at night and flares back up in the morning. It was not as inflamed and itchy by the end of the day and she guessed it's from the Allegra and Pepcid she takes at night but she wakes up covered. The patient underwent lab tests and procedures which included bloodwork: low IGA, CBC: unknown, CMP: unknown, sed rate: unknown, all on an unspecified date. Therapeutic measures were taken as a result of hives and they are welts and her eyes are swollen shut. The outcome of the event hives was not recovered, and the outcome of the other events were unknown.  Information on the lot/batch number has been requested.; Sender's Comments: A possible contributory effect of suspect BNT162B2 on reported hives cannot be excluded.  The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.