Sex: F
Vaccine: COVID19
Symptoms: Peripheral swelling, Pyrexia, Red blood cell abnormality, Red blood cell count
Clinical narrative: she almost died; destroyed her hemoglobin/hemoglobin was 6 (normal level 14); little fever; very bad flare-up; shortness of breath; legs and feet got swollen; immature red blood cells; This is a spontaneous report received from a Consumer or other non HCP. Other Case identifier(s): LRN5071002.  A 58-year-old female patient received BNT162b2 (BNT162B2), in Apr2021 as dose 2, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history included: "Rheumatoid arthritis" (ongoing). Concomitant medication(s) included: PREDNISONE. Past drug history included: Leflunomide. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, Lot number: Unknown), for COVID-19 immunization. The following information was reported: NEAR DEATH EXPERIENCE (medically significant), outcome "unknown", described as "she almost died"; HAEMOGLOBIN DECREASED (non-serious), outcome "unknown", described as "destroyed her hemoglobin/hemoglobin was 6 (normal level 14)"; PYREXIA (non-serious), outcome "unknown", described as "little fever"; ARTHRITIS (non-serious), outcome "unknown", described as "very bad flare-up"; DYSPNOEA (non-serious), outcome "unknown", described as "shortness of breath"; PERIPHERAL SWELLING (non-serious), outcome "unknown", described as "legs and feet got swollen"; RED BLOOD CELL ABNORMALITY (non-serious), outcome "unknown", described as "immature red blood cells". The event "destroyed her hemoglobin/hemoglobin was 6 (normal level 14)" required emergency room visit. The patient underwent the following laboratory tests and procedures: Haemoglobin: destroyed; 6, notes: hemoglobin was 6 (normal level 14); Red blood cell count: immature. Therapeutic measures were taken as a result of near death experience.  Clinical course: It was reported that the patients medical history was not reported. On unknown date, it was reported that patient experienced: The patient reported that in Apr2021, before she was on Actemra, she received her second COVID vaccine (Pfizer vaccine), and it screwed up her immune system very badly-actually it destroyed her hemoglobin. The patient stated that she didn't have much reaction to her first COVID vaccine, but with the second one she had a little fever, had a little reaction, and 2 weeks after she developed a very bad flare-up. She further described the flare-up as she "could barely hold her" (patient did not finish that her biggest complaint is her hands and feet but this time it was joints all over her body. A few months after that, she developed shortness of breath and her legs and feet got swollen. Her husband took her to the emergency room and her hemoglobin was 6 (normal level 14). She almost died-they told her that they couldn't save her and gave her a blood transfusion. She has not had any COVID boosters. She stated that for her blood test, she has immature red blood cells and has had pretty bad blood work since then. It a so provoked a big flare-up, which is why her HCP told her to start Actemra in the first place. She couldn't get her rheumatoid arthritis under control after that second COVID vaccine in Apr2021; she had previously been on leflunomide and prednisone 5mg. After the COVID vaccine, she had to increase prednisone to 40mg and it still didn't help her. She stated that starting Actemra has helped, and she started to feel much better. The outcome of the reported event(s) was Unknown.  Batch/lot number is not provided, and it cannot be obtained.