Age: 43.0
Sex: F
Vaccine: COVID19
Symptoms: Pain, Pain in extremity, Paraesthesia
Clinical narrative: neuropathy; lower back pain that spread to her legs; lower back pain that spread to her legs/spread to her hands and it had spread to her feet; tingling; burning sensation and numbness mainly in her legs/back, hands, feet and in her shoulders this sensations come and go; burning sensation and numbness mainly in her legs; severe pain/sometimes spread to her shoulders; severe pain/It was her full body; This is a spontaneous report from a contactable consumer. This consumer reported for 43-year-old female patient (sister) received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE) in the arm on 10Mar2021 (lot: EN6205) at single dose for COVID-19 immunisation. Medical history included Juvenile rheumatoid arthritis, diagnosed 20 years ago (2001) and she was in remission. Previously she had a bilateral hip replacement but that was 20 years ago (2001), there had been nothing new since then.  Concomitant medications were not reported. The patient previously received first dose of BNT162B2 on 09Feb2021 (Lot Number: EC3247) for COVID-19 immunisation.  On 12Mar2021, patient started experiencing adverse reaction, lower back pain that spread to her legs, mainly in the quarter area (deep leg pain). They have been to ER twice. She's also experiencing tingling, burning sensation and numbness mainly in her legs but also in her back, hands, feet and in her shoulders, this sensations come and go. Patient was in severe pain, it was at 9/10, and it was in her lower back and her quads area, it sometimes spread to her shoulders and hands and it had spread to her feet on both sides for all of these. It was her full body. It's been already three weeks after the vaccine and the doctors told her that this was caused by the vaccine and they're not sure how to treat her. In the emergency room the other day had given her codeine, which didn't work, and she didn't like the way she felt when she took that so she didn't take it anymore,  and they had also given her morphine (it was an injection given at the hospital through an IV drip) and she was still in pain under the morphine, which didn't work.  At first, they had prescribed patient hydrocodone and it didn't help her at all. She is now on one more new medication. Patient was on prednisone 60 mg, and she started this medication on 30Mar2021, and they wouldn't say it was helping her too much and that was a pretty big steroid dose. They gave patient prednisone 20 mg on 29Mar2021, and that didn't help at all and she ended up back in the emergency room so they hyped up her prednisone dosage to 60 mg on 30Mar2021 and was still taking this medication. Patient was using the lidocaine patches 5% (NDC: 0591352511, Lot Number: 1396641, and expiry: Jun2022), and reported that it was not helping with her specific issue and she was wanting to explain that, it is not that they didn't work, it was just not specifically helping patient for the current pain that she was having.  Additional treatment included methylprednisone (NDC: 68382-916-34, Lot Number: M008443, Expiry: Jul2022): this was the original dose of the type of prednisone that patient was on. It was 4 mg per pill by mouth and that didn't work. It was in a manufacturer pack. Patient only took it one day because it wasn't helping and then when they went back to the emergency room they gave her the 10 mg per pill instead of the 4 mg per pill taper package. Tramadol: from 23Mar2021 and she was still taking this medication, at 50 mg, one tablet by mouth three times daily as needed. She was taking this for the same reason as above, to try and figure out what will reduce the pain. The providers wanted to see if this is muscular pain, or whatever it is, this is used to try and reduce it. Cyclobenzaprine: from15Mar2021 and she was still taking this medication, at 5 mg, one tablet by mouth three times daily for the pain. Gabapentin: On 15Mar2021 patient was originally taking 300 mg put then she was hiked up to taking 600 mg by the neurologist starting on 30Mar2021. She had been taking 600 mg three times a day by mouth since 30Mar2021 and she was still taking that dosage. Amitriptyline: from 15Mar2021 and she was still taking this medication, at 25 mg once a day by mouth.  As of follow up information on 19Apr2021, the consumer reported that patient had formally been diagnosed with COVID vaccine induced neuropathy on unspecified date. Patient had been to the emergency room 4 times and hospitalized once. The patient went to the emergency room for the 4th time on 08Apr2021 and was admitted that night at midnight, hospitalized from 09Apr2021 to 12Apr2021. The patient is now on the medication as follows: Hydromorphone- 2mg tablets, one tablet every 4 hours as needed; Morphine extended release- 15 mg one tablet 3 times daily; Dexamethasone- 2mg tablets tapered down; Pregabalin- 300 mg 3 times daily; Cefradine (VELODYNE)- 10mg once daily. The patient's providers had been changing the patient's medication a lot. Now the patient is on hydromorphone hydrochloride (DILAUDID) and morphine and nothing is happening.  The outcome of tingling, burning sensation and numbness was not recovered, outcome of other events was unknown.