Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Arthralgia, Brain fog, Condition aggravated, Feeling abnormal, Headache
Clinical narrative: Memory problem; a swollen gland under her left armpit; Flu like symptoms; Headache; Nausea; Achy joints; Feeling badly; Postherpetic Neuralgia; felt like her brain was messed up and she could not remember how to get to a place; Pain; This non-serious case was reported by a consumer via call center representative and described the occurrence of post herpetic neuralgia in a 76-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included shingles (had a case of shingles a few years ago (no exact date provided) prior to receiving Shingrix) and post herpetic neuralgia (had post herpetic neuralgia (PHN) in her right eye at that time).   On 20-JUN-2023 15:00, the patient received the 1st dose of Shingrix (left arm). In JUN-2023, an unknown time after receiving Shingrix, the patient experienced memory disturbance (Verbatim: Memory problem), pain (Verbatim: Pain) and brain fog (Verbatim: felt like her brain was messed up and she could not remember how to get to a place). On 21-JUN-2023, the patient experienced post herpetic neuralgia (Verbatim: Postherpetic Neuralgia), axillary lymph nodes enlarged (Verbatim: a swollen gland under her left armpit), influenza-like symptoms (Verbatim: Flu like symptoms), headache (Verbatim: Headache), nausea (Verbatim: Nausea), joint pain (Verbatim: Achy joints) and feeling bad (Verbatim: Feeling badly). The patient was treated with paracetamol (Tylenol). In JUN-2023, the outcome of the memory disturbance was resolved.  On 21-JUN-2023, the outcome of the influenza-like symptoms, headache, nausea, joint pain and feeling bad were resolved. The outcome of the post herpetic neuralgia, axillary lymph nodes enlarged and pain were not resolved and the outcome of the brain fog was not reported.   It was unknown if the reporter considered the post herpetic neuralgia, memory disturbance, axillary lymph nodes enlarged, influenza-like symptoms, headache, nausea, joint pain, pain, feeling bad and brain fog to be related to Shingrix.     It was unknown if the company considered the post herpetic neuralgia, memory disturbance, axillary lymph nodes enlarged, influenza-like symptoms, headache, nausea, joint pain, pain, feeling bad and brain fog to be related to Shingrix.   Additional Information: GSK receipt date: 22-Jun-2023 The patient received a dose of Shingrix and reported that she woke up at 6 pm, feeling badly with flu like symptoms, achy joints, nausea and headache. The patient also reported that she woke up with a swollen gland under her left armpit and she still has soreness on the day of reporting.  These symptoms stopped that same day, after taking Tylenol, with the headache going away after she went to bed that evening. The patient also reported that on 21st June 2023, she felt like her brain was messed up and she could not remember how to get to a place she had been multiple times before, in the afternoon and into the evening, and it was frightening.  The patient reported that the post herpetic neuralgia returned, after receiving the first dose of Shingrix.  The patient reported that the post herpetic neuralgia was behind her right eye, and she felt pain when she closes her eye, and she was still having this problem on the day of reporting.