Age: 60.0
Sex: M
Vaccine: COVID19
Symptoms: Cerebrovascular accident, Rash, Skin fissures, Speech disorder, Urticaria
Clinical narrative: had a stroke/it almost killed me/ I couldn't remember anybody's name at work/ he says that he is stuttering because the stroke has made him talk like this/ His thinking has become slow in/my brain doesn't work the same anymore/He says that it has; received a call from my brother and I couldn't speak on the phone/it affected my speech/still affecting my speech/There was nothing but mumbling coming out of his mouth; it also gave me the hives; rashes were all over his body from head to toe/my armpits, crack in my rear end, my crotch, all over my legs, back, stomach, chest, face; my body was cracking; This spontaneous case was reported by a patient and describes the occurrence of CEREBROVASCULAR ACCIDENT (had a stroke/it almost killed me/ I couldn't remember anybody's name at work/ he says that he is stuttering because the stroke has made him talk like this/ His thinking has become slow in/my brain doesn't work the same anymore/He says that it has aff), SPEECH DISORDER (received a call from my brother and I couldn't speak on the phone/it affected my speech/still affecting my speech/There was nothing but mumbling coming out of his mouth), URTICARIA (it also gave me the hives), RASH (rashes were all over his body from head to toe/my armpits, crack in my rear end, my crotch, all over my legs, back, stomach, chest, face) and SKIN FISSURES (my body was cracking) in a 60-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 046A21A and 025L20A) for COVID-19 prophylaxis.     No Medical History information was reported.   On 18-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) .5 milliliter. On 17-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .5 milliliter. On 19-Mar-2021, the patient experienced CEREBROVASCULAR ACCIDENT (had a stroke/it almost killed me/ I couldn't remember anybody's name at work/ he says that he is stuttering because the stroke has made him talk like this/ His thinking has become slow in/my brain doesn't work the same anymore/He says that it has aff) (seriousness criteria hospitalization and medically significant), SPEECH DISORDER (received a call from my brother and I couldn't speak on the phone/it affected my speech/still affecting my speech/There was nothing but mumbling coming out of his mouth) (seriousness criterion hospitalization), URTICARIA (it also gave me the hives) (seriousness criterion hospitalization), RASH (rashes were all over his body from head to toe/my armpits, crack in my rear end, my crotch, all over my legs, back, stomach, chest, face) (seriousness criterion hospitalization) and SKIN FISSURES (my body was cracking) (seriousness criterion hospitalization). The patient was treated with BETAMETHASONE DIPROPIONATE (BETAMETHASONE DIPROPIONATE AUGMENTED) in March 2021 for Hives, at an unspecified dose and frequency; HYDROCORTISONE (topical) in March 2021 for Hives, at a dose of 2.5%; TRIAMCINOLONE ACETONIDE (topical) in March 2021 for Hives, at a dose of 0.5%; HYDROCORTISONE (topical) in March 2021 for Hives, at a dose of 2.5% and PARAFFIN (VASELINE [PARAFFIN]) (topical) in March 2021 for Hives, at an unspecified dose and frequency. In July 2021, URTICARIA (it also gave me the hives), RASH (rashes were all over his body from head to toe/my armpits, crack in my rear end, my crotch, all over my legs, back, stomach, chest, face) and SKIN FISSURES (my body was cracking) had resolved. At the time of the report, CEREBROVASCULAR ACCIDENT (had a stroke/it almost killed me/ I couldn't remember anybody's name at work/ he says that he is stuttering because the stroke has made him talk like this/ His thinking has become slow in/my brain doesn't work the same anymore/He says that it has aff) had not resolved and SPEECH DISORDER (received a call from my brother and I couldn't speak on the phone/it affected my speech/still affecting my speech/There was nothing but mumbling coming out of his mouth) had resolved.            Concomitant product use was not provided by the reporter.  After second dose of vaccine, patient couldn't say anything. Patient's brother called 911 after which an ambulance arrived at caller's home later the ambulance took patient to a hospital, where patient was hospitalized for about 4-5 days. patient was confirmed to had stroke. patient was told that he had oodles/a bunch of mini strokes. It almost killed him. The stroke did not affect patients walking ability or affect his arms or face. a couple days after receiving the 2nd dose of the Moderna vaccine, patient started experiencing hives. The rashes were all over patients body from head to toe, in armpits, in patients crack in the rear end,crotch area, all over legs, back, stomach, chest, and face. patient says that it was everywhere except hands and bottom of the feet. It may have also been in between his toes. patient said that the way he felt with the hives was like murder. Patient's body was cracking and he had cracks everywhere. It became difficult for him to move. His wife had to apply Vaseline all over his body.  Company comment: This spontaneous case concerns a 60-year-old, male patient with no medical history reported, who experienced the unexpected, serious (Hospitalization, medically significant) AESI event of cerebrovascular accident (had a stroke/it almost killed me) 2 days after receiving the 2 dose of mRNA-1273 Vaccine in the covid 19 vaccination series, with symptoms of Memory Impairment and Mumbling the next day, followed by Dysphemia, Bradyphenia and Gait Disturbance the following day. He also experienced the other serious (Hospitalization) events of Urticaria, rash and Skin fissures 2 days after the vaccination and was hospitalized and was told that he had a bunch of mini strokes. The stroke did not affect patients walking ability or affect his arms or face. the rashes were all over patient's body except hands and bottom of the feet. patient's body was cracking and he had cracks everywhere. the patient was treated with betamethasone dipropionate, hydrocortisone (topical) 2.5%; triamcinolone acetonide (topical) 0.5%; hydrocortisone (topical) 2.5% and paraffin (vaseline [paraffin]) (topical) in march 2021 for hives. The events had resolved. Details of risk factors, labs, diagnostic tests, comorbidities were not provided. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed per medical judgement.   This case was linked to MOD-2021-018248 (Patient Link).; Sender's Comments: This spontaneous case concerns a 60-year-old, male patient with no medical history reported, who experienced the unexpected, serious (Hospitalization, medically significant) AESI event of cerebrovascular accident (had a stroke/it almost killed me) 2 days after receiving the 2 dose of mRNA-1273 Vaccine in the covid 19 vaccination series, with symptoms of Memory Impairment and Mumbling the next day, followed by Dysphemia, Bradyphenia and Gait Disturbance the following day. He also experienced the other serious (Hospitalization) events of Urticaria, rash and Skin fissures 2 days after the vaccination and was hospitalized and was told that he had a bunch of mini strokes. The stroke did not affect patients walking ability or affect his arms or face. the rashes were all over patient's body except hands and bottom of the feet. patient's body was cracking and he had cracks everywhere. the patient was treated with betamethasone dipropionate, hydrocortisone (topical) 2.5%; triamcinolone acetonide (topical) 0.5%; hydrocortisone (topical) 2.5% and paraffin (vaseline [paraffin]) (topical) in march 2021 for hives. The events had resolved. Details of risk factors, labs, diagnostic tests, comorbidities were not provided. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed per medical judgement.