Age: 14.0
Sex: F
Vaccine: COVID19
Symptoms: Drug ineffective, Headache, Investigation, Magnetic resonance imaging, Nasal congestion
Clinical narrative: Her daughter had both Pfizer COVID shots, and she still got COVID bad .; Her daughter had both Pfizer COVID shots, and she still got COVID bad .; 104.5 fever; body aches; nausea; headaches; sore throat; coughing; congestion; wheezing; chest pain; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from product quality group. The reporter is the parent.  A 14 year-old female patient received bnt162b2 (BNT162B2), administration date 09Jun2021 (Lot number: EW0177) at the age of 14 years as dose 2 (tris), single and administration date 18May2021 (Lot number: EW0185) as dose 1 (tris), single for covid-19 immunisation. Relevant medical history included: "stress fracture" (unspecified if ongoing); "pneumonia" (unspecified if ongoing), notes: Her daughter has had pneumonia before in the past.; "asthma" (unspecified if ongoing), notes: She does have a history of asthma. Concomitant medication(s) included: DESVENLAFAXINE SUCCINATE; PROZAC. The following information was reported: DRUG INEFFECTIVE (medically significant), SUSPECTED COVID-19 (medically significant), outcome "unknown" and all described as "Her daughter had both Pfizer COVID shots, and she still got COVID bad ."; PYREXIA (non-serious), outcome "unknown", described as "104.5 fever"; PAIN (non-serious), outcome "unknown", described as "body aches"; NAUSEA (non-serious), outcome "unknown", described as "nausea"; HEADACHE (non-serious), outcome "unknown", described as "headaches"; OROPHARYNGEAL PAIN (non-serious), outcome "unknown", described as "sore throat"; COUGH (non-serious), outcome "unknown", described as "coughing"; NASAL CONGESTION (non-serious), outcome "unknown", described as "congestion"; WHEEZING (non-serious), outcome "unknown", described as "wheezing"; CHEST PAIN (non-serious), outcome "unknown", described as "chest pain". The patient underwent the following laboratory tests and procedures: blood glucose: between 69-70 ., notes: She has also been experiencing low sugar in the mornings between 69-70 ; blood test: fine; body temperature: 104.5; investigation: unknown results; magnetic resonance imaging: unknown results; sars-cov-2 test: negative; weight: lost 6, notes: Her daughter had also lost weight in the last week. in the last 2 weeks her daughter has lost 6 lbs because of no appetite. Her daughter just doesn't want to eat. Therapeutic measures were taken as a result of cough, nasal congestion, wheezing, chest pain.  Additional Information: The mother is on the line reporting a side effect for her daughter who started generic Pristiq, Desvenlafaxine. Her daughter was previously put in a boot on her right foot, and she had 90% range of motion. Recently, they took the boot off, and she only has 30% range of motion. They are noticing the same thing in the left foot as well. The caller confirmed the details provided by the transferring agent. Her daughter had been on the lower dose of 25mg a month before, but they upped it the beginning of this month to 50mg. She noticed her daughter couldn't walk flat on her foot. She was walking tip toed. Her daughter had no range of motion. The therapist couldn't push her daughter's foot past 30% range of motion. At first they thought maybe it was a side effect of COVID. Then, she read that generic Pristiq, Desvenlafaxine could cause Rigidity. So then, they began to believe it was the medicine instead. Her daughter had COVID two weeks ago. Her daughter was having trouble bending her toes. Her daughter was walking on the ball of her foot. She was walking on the ball of her left foot. So her mom made an appointment for her left foot. Separate from her follow up from her right foot that was in a boot due to a stress fracture. Her daughter had also lost weight in the last week. in the last 2 weeks her daughter has lost 6 lbs because of no appetite. Her daughter just doesn't want to eat. She has also been experiencing low sugar in the mornings between 69-70. Her daughter's doctor referred her to a Pediatric Neurologist. The increased her daughter's generic Pristiq, Desvenlafaxine dose because they saw no change in behavior at 25mg. The Psychiatrist upped the medication. The doctor waited until her daughter was done with COVID to start the higher dose of generic Pristiq, Desvenlafaxine. Her daughter started the 50mg on 25Dec2021. The 50mg generic Pristiq has Lot: 2105075. There is a prescription label covering the rest. The 25mg generic Pristiq, Desvenlafaxine , has lot 2105005629. The information is bigger on that bottle. It says Generic brand of Pfizer Pristiq. Desvenlafaxine Succinate ER-24 is what the prescription says. The previous dose was not working. They did a genetic test, and Pristiq was only one of 4 medications that would be compatible with her. Her daughter tried Prozac and other medications she can't remember with no results. She got rid of the bottles. She was always worried she may give her daughter something she shouldn't have received so she always disposes of old medications. She doesn't have any NDC/lot/expirations. Her daughter is still taking the Desvenlafaxine as of today, but this will be her last dose. The mom wants to see if the side effects improve. It seems it has only gotten worse for her so the mom decided to stop it. She had blood work done which was fine. She has a MRI on Monday, and a nerve test on Monday. She does have a history of asthma. Her daughter had both Pfizer COVID shots, and she still got COVID bad. The mom wondered if she had it for a little while. She kept having negative tests. Her daughter had 104.5 fever, body aches, nausea , headaches, and a sore throat. Her first COVID dose had lot number EW0185, and was given on 18May2021, it was the Pfizer COVID pediatric dose. Her second dose had lot number EW0177, and was given on 9Jun2021, and it was the Pfizer COVID pediatric dose. Her daughter has had pneumonia before in the past.  Her daughter is experiencing coughing, congestion, and wheezing. She is also experiencing chest pain so they put her on Albuterol. Her daughter tested negative for COVID on Monday.