Sex: U
Vaccine: HPV4
Symptoms: Marital problem, Muscle twitching, Myocardial infarction, Nightmare, Orthopox virus infection
Clinical narrative: two instances where I spent several days in a hospital fighting for my life; weakened immune system/CD4 count go down significantly; sepsis; fever, shivering uncontrollably; sharp pains all over; body went into shock; spine was twitching; could not walk; developed orthopox which gave 13 diseases in one, with total count of 24 diseases at one time; develop orthopox which gave 13 diseases in one with a total count of 24 at one time; lung cancer / cancer; lymphoma; lymphadenopathy; splenomegaly; cancer; upper respiratory tract infection with MRSA/staph; upper respiratory tract infection with MRSA/Staph; anthrax; pneumonia; renal failure; nodules in lung; POTS / fainting when stand; brain fog; memory loss; felt depressed, crying a lot more, tremendous change in life enjoyment, challenging to rise from bed on certain days, the burden and difficulties of aquiring coffee and tending to personal hygene intensified/lethargic/sadness; Quarrelsomeness extremely changed; alcohol consumption went up high; change in anxiety level: highly/ apprehensive about the prospect of death; tremendous amounts of stress/ gathering documents keeps me stressed out to the max; nightmares; suspended off medications because it stopped working; enlarged heart; my HIV status has been a victim of a lot of this / making infection stronger/ weakened immune system; heart attack; liver failure; vaccine failure; Information has been received from a 33-year-old patient (pt) of unknown gender regarding case in litigation. The pt's concurrent conditions included human immunodeficiency virus (HIV) infection. The pt's medical history and concomitant medications were not reported. On 16-AUG-2022, the pt underwent orthopoxvirus DNA, ql polymerase chain reaction (PCR) test which showed low positive (also reported as detected, out of range).  On 12-MAY-2023 at around 9:00, the pt was vaccinated with the second dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot# and expiry date were not provided), for prophylaxis.  On the same date (reported as that evening), the pt traveled and while on the train "the pt's life went to bad and back". The pt's body went into shock, spine was twitching with sharp pains all over. The pt ran a fever with uncontrollable shivering once the train approached the next station. The pt could not walk and EMS took the pt to the ER from there. The pt spent the next 5 days in intensive unit care (ICU) "clinging to life", with the resident physician telling each night "I do not expect to see you tomorrow when I arrive to work". The pt was given pain medications around the clock (morphine) and had CD4 count went down so significantly to where it was decided to put the pt down as well with shot in the back of arm. The pt was diagnosed with cancer, "Staph" and sepsis. As the pt was out of state, the vaccine record could not be seen to attribute the failure. The pt also developed orthopox which gave 13 diseases in one, with a total count of 24 at one time. As a result, the pt experienced the following injuries: vaccine failure, sepsis (described above), renal failure, lung cancer, lymphoma, lymphadenopathy, pneumonia, splenomegaly, upper respiratory tract infection methicillin-resistant Staphylococcus aureus (MRSA), anthrax, nodules in lung, enlarged heart and heart attack. Due to "this entire circumstance", the pt's life was completely upended. The pt was confronted with health issues that would have never encountered if this "unfortunate incident" had not occurred. A heart attack, postural orthostatic tachycardia syndrome (POTS), a decline in quality of life, even fainting when stand, and the two instances where the pt spent several days in the hospital fighting for life. The pt lost job, the pt's marriage crumbled, the pt was evicted, and at that time the pt was how the harm experienced is or is not linked to the discrimination and/ or retaliation experienced at issue in complaint. The pt was asked if felt depressed and answered that ever since this incident occurred, it has become progressively challenging to rise from bed on certain days. The burden and difficulties of acquiring coffee and tending to personal hygiene have intensified. Answering the question if the depressed feeling was short or long-term, the pt stated it was a blend of both factors. This disease could be held responsible for both, the brain fog and memory loss. The pt's quality of life significantly declined. The pt stated that did not feel depressed prior to vaccination with quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL). At that time, the pt was apprehensive about the prospect of death which was significantly impacting daily routines. The pt experienced nightmares. The pt's reaction toward work changed. It was harder to find trust in employer, always lethargic and lacking the personal drive to get the job done. The pt allowed to auto place at fault of situations as they occurred. The pt was also crying a lot more. The pt experienced damage to professional and/or personal reputation, a change in the level of emotional distress. The amount of alcohol consumption went up so high that the pt started to suffer from liver failure. There was also an extreme change in the pt's quarrelsomeness. The pt admitted that developing relationships was rather difficult recently. The pt also experienced a change in the stress level. Even at that time, the buildup of this case, gathering documents kept the pt stressed out to the max. The pt noticed a high change in the anxiety level. Spiritual coping was a help for the pt who was still a little uncertain about opening up and talking about this with anyone. The pt experienced a tremendous change in enjoyment of life. The pt's attitude toward others also changed. It caused the pt to think cautiously about every encounter with someone. The pt HIV status was "the victim of a lot of this". Tremendous amounts of stress caused the pt's immune system to weaken thus making infection stronger. The pt was even suspended off the medication (medication name was not provided) because it stopped working. The pt's consequential damages referred to the pt's marriage and loss of career. The outcome of all events was unknown.  The reporter considered all events to be related to quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL).  Upon internal review, sepsis, shock, renal failure, lung cancer, lymphoma, pneumonia, anthrax, liver failure, HIV disease progression and heart attack were determined to be medically significant.  The reporter considered sepsis; shock; spine twitching; could not walk; developed orthopox which gave 13 diseases in one, with total count of 24 diseases at one time; lung cancer; lymphoma; upper respiratory tract infection MRSA; hospitalization and weakened immune system to be life-threatening.  All available medical records will be provided upon request.