Age: 48.0
Sex: F
Vaccine: COVID19
Symptoms: Hot flush, Insomnia, Menstrual disorder, Menstruation irregular, Myalgia
Clinical narrative: distractive and extremely uncomfortable at work, disruptive; fully awaikning at night; Hot flush; cold sore; muscle soreness/ body aches; fatigue; hot flashes and changes in cycle; hot flashes and changes in cycle; Rising heat sensation in upper body, chest, arm, shoulder, face; patient had regular period in june but then she did not have her period in July and still no period as of now in August; cold sweats; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of HOT FLUSH (hot flashes and changes in cycle), MENSTRUAL DISORDER (hot flashes and changes in cycle), ORAL HERPES (cold sore), COLD SWEAT (cold sweats) and DISTRACTIBILITY (distractive and extremely uncomfortable at work, disruptive) in a 48-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 021C21A and 021C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Vitamin D deficiency since 2019 and Cold sores (Last one more than 6 months ago). Concomitant products included VITAMIN D NOS for Vitamin D deficiency.   On 06-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 02-Jun-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 02-Jun-2021, the patient experienced HOT FLUSH (hot flashes and changes in cycle), MENSTRUAL DISORDER (hot flashes and changes in cycle), FEELING HOT (Rising heat sensation in upper body, chest, arm, shoulder, face) and MENSTRUATION IRREGULAR (patient had regular period in june but then she did not have her period in July and still no period as of now in August). On 03-Jun-2021, the patient experienced MYALGIA (muscle soreness/ body aches) and FATIGUE (fatigue). In June 2021, the patient experienced COLD SWEAT (cold sweats). On 16-Jun-2021, the patient experienced ORAL HERPES (cold sore). In July 2021, the patient experienced HOT FLUSH (Hot flush). On an unknown date, the patient experienced DISTRACTIBILITY (distractive and extremely uncomfortable at work, disruptive) and INSOMNIA (fully awaikning at night). On 05-Jun-2021, MYALGIA (muscle soreness/ body aches) and FATIGUE (fatigue) had resolved. On 24-Jun-2021, ORAL HERPES (cold sore) had resolved. At the time of the report, HOT FLUSH (hot flashes and changes in cycle) had resolved, MENSTRUAL DISORDER (hot flashes and changes in cycle), COLD SWEAT (cold sweats), FEELING HOT (Rising heat sensation in upper body, chest, arm, shoulder, face), MENSTRUATION IRREGULAR (patient had regular period in june but then she did not have her period in July and still no period as of now in August) and HOT FLUSH (Hot flush) had not resolved and DISTRACTIBILITY (distractive and extremely uncomfortable at work, disruptive) and INSOMNIA (fully awaikning at night) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In November 2020, Blood test: normal (normal) Normal general health, including thyroid functions.         It was reported that patient had a cold sore for a couple of days after second dose of the vaccine. Patient experienced hot flashes almost hourly after about 3 weeks after second dose. It was reported that patient had sudden heat in face and upper body for about a minute and then cold sweats afterwards, about 10 times a day around the clock. She reported that her normal period was in June and then didn't have it since (25 days late according to calendar).  No treatment medication was reported.   Most recent FOLLOW-UP information incorporated above includes: On 13-Aug-2021: significant follow up appended, added patient medical history, concomitant medication, and event details. On 14-Aug-2021: Follow-up received on 14-AUG-2021, included no new information.