Age: 51.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Malaise
Clinical narrative: Pain is in the right shoulder; Diagnosed with Arthritis; Diagnosed with Inflammation in the right ankle; Could not walk; This spontaneous case was reported by a patient and describes the occurrence of INFLAMMATION (Diagnosed with Inflammation in the right ankle), GAIT INABILITY (Could not walk), ARTHRITIS (Diagnosed with Arthritis) and ARTHRALGIA (Pain is in the right shoulder) in a 51-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 048L21A, 053F21A, 031421A and 012M20A) for COVID-19 vaccination.     The patient's past medical history included Injury (He had injuries on the left side of the body).   On 13-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 13-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 09-Jul-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 23-Jul-2022, the patient experienced INFLAMMATION (Diagnosed with Inflammation in the right ankle) and GAIT INABILITY (Could not walk). On 30-Jul-2022, the patient experienced ARTHRITIS (Diagnosed with Arthritis). On an unknown date, the patient experienced ARTHRALGIA (Pain is in the right shoulder). The patient was treated with IBUPROFEN for Inflammation, at an unspecified dose and frequency and DICLOFENAC (VOLTAREN [DICLOFENAC]) for Pain, at an unspecified dose and frequency. At the time of the report, INFLAMMATION (Diagnosed with Inflammation in the right ankle) and GAIT INABILITY (Could not walk) outcome was unknown and ARTHRITIS (Diagnosed with Arthritis) and ARTHRALGIA (Pain is in the right shoulder) had not resolved.            No concomitant medications reported.  On 08-Aug-2021, patient received first booster and on 09-Jul-2022, patient received second booster.  It was reported that 2 weeks after the 2nd Monovalent booster (4th shot), patient developed pain in the right ankle. Felt like patient sprained the right ankle. The patient visited a medical doctor and was diagnosed with Inflammation. Pain moved to the right Knee and could not walk. patient went back to MD and was diagnosed with Arthritis. If patient stoped taking Voltaren, the pain came back. The pain was in the right shoulder as well. Patient never had Arthritis before vaccination. Patient had injuries on the left side of the body but the Arthritis was attacking the healthy joints, only on the right side of  the body.  Company Comment: This is a spontaneous case concerning a 51-year-old male patient with no relevant medical history, who experienced the unexpected, non-serious adverse event of special interest of Arthritis. 14 days after receiving the fourth dose of mRNA-1273 vaccine, the patient developed pain in the right ankle and was diagnosed with inflammation and prescribed Ibuprofen. 21 days after receiving the fourth dose of mRNA-1273 vaccine, the pain moved to the right knee and could not walk. The patient went back to the doctor and was diagnosed with Arthritis. The pain is relieved by taking the prescribed Diclofenac. Relevant diagnostic tests was not provided in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-677265 (Patient Link).; Sender's Comments: This is a spontaneous case concerning a 51-year-old male patient with no relevant medical history, who experienced the unexpected, non-serious adverse event of special interest of Arthritis. 14 days after receiving the fourth dose of mRNA-1273 vaccine, the patient developed pain in the right ankle and was diagnosed with inflammation and prescribed Ibuprofen. 21 days after receiving the fourth dose of mRNA-1273 vaccine, the pain moved to the right knee and could not walk. The patient went back to the doctor and was diagnosed with Arthritis. The pain is relieved by taking the prescribed Diclofenac. Relevant diagnostic tests was not provided in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.