Sex: M
Vaccine: HIBV
Symptoms: Autism, Drug toxicity, Encephalopathy, Neurodevelopmental disorder, Psychomotor hyperactivity
Clinical narrative: This case was considered medically important for the events of autism, ADHD disorder and encephalopathy (OMIC). Medical records regarding Hib vaccine were received from an attorney regarding a male pt who received a dose on an unspecified date and experienced childhood autism, toxic encephalopathy, ADHD and mercury poisoning. The pts concurrent illnesses included testicular hyperfunction, precocious puberty and amino acid metabolism disorder (Sulphur bearing), Pt had fetal exposure to RH D immune globulin Human. Indication for Hib was immunisation. Product was administered on an unspecified date. Dose regimen was 1 dose 1 time per day. Additional suspect vaccines included Pertussis vaccine and Unspecified vaccines. Concomitant medications were not reported. On an unspecified date, the pt received a dose of Hib vaccine. ON 7/27/1998, at the age of 30 months, the child was evaluated by a physician and noted to have developmental difficulties. The child preferred solitary as opposed to interactive play, had restricted interests, and had been delayed in language acquisition from both a receptive as well as expressive standpoint. On the same day, the pt was diagnosed with child hood autism. Treatment included cod liver oil and B6 and B complex vitamins. Within three days of receiving Vit A therapy through cod liver oil, the child responded better to verbal cues and had an increase in vocalization. Additional treatment included taurine, bethanechol, acidophilus, calcium, magnesium, manganese, zinc, EPADHA, nystatin, evening primrose, calcium butyrate, glutathion, and milk thistle. The child was placed on a gluten free and casein free diet. On 9/22/00, the pt was seen by another physician and was noted to have improved focus, attention, interaction and outward expression. On the same day, the pt was diagnosed with mercury poisoning. Treatment included Chelation. On 12/2/01, lead urine was 24 ug/g creatinine, while urine mercury was 3.7 ug/g creatinine. On an unspecified date, the pt developed ADHD. Treatment included Clonidine and Tenex. In 2002, stool analysis showed it was high above the 68th percentile in antimony, arsenic, bismuth, lead and nickel, thallium and uranium excretion, while mercury was slightly below th e68th percentile. On 4/22/02, the child was seen by the physician, who noted that a double defect in the G Protein adjacent to an L type calcium channel leaving it in an open position was the probable etiology of the autism. Additional treatment included Nimotop. On 10/1/05, the child was evaluated by another physician, who noted that the pts neurodevelopmental disorder was an apparent result of toxic encephalopathy, which was caused and begun by fetal mercury exposure from RH D immune globulin human and exacerbated by mercury poisoning by therapeutic use of pertussis and unspecified vaccines. The physician also reported that child had biochemical markers, including low cysteine, low sulphate, low glutathion and high testosterone, that indicated a heightened sensitivity to mercury. It was unknown if the pt recovered from the events. No additional information was available at the time of this report.