Age: 50.0
Sex: F
Vaccine: COVID19
Symptoms: Computerised tomogram head, Gait disturbance, Intraocular pressure test, Investigation, Magnetic resonance imaging spinal
Clinical narrative: Left eye central vision loss; Back pain; Hip/Knees pain; Blurred vision; Limping R leg; This is a spontaneous report from a contactable nurse (patient).  A 50-year-old non-pregnant female patient received first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 VACCINE), intramuscularly administered in Deltoid Left on 21May2021 11:52, at 50-year-old, as single dose (Lot Number: EW0183) for covid-19 immunisation.  Medical history included eye surgeries stagBlue for over 12 years until after the COVID shot. Concomitant medication included influenza vaccine inact split 3v (FLUARIX) taken for an unspecified indication, via intramuscular in right deltoid, at 50-year-old, as single dose (Lot number: 59HN3) on 01Apr2021. The patient had not got covid prior vaccination and had not been tested covid post vaccination. No Known allergies. On 21May2021, the patient experienced blurred vision and limping right leg. On 22May2021(reported as "22May - 24May"), the patient had left eye central vision loss (medically significant and disability), back pain (disability), hip and knees pain(disability). The patient underwent lab tests and procedures which included angiogram: retinal surgeon did angiogram and confirmed revascularization on 2021; Fluorescent Angioscopy: left subretinal revascularization on 27Aug2021; CT (Computerised tomogram) Scan Head Brain: normal and No mass. No stroke on 28Jun2021; Eye pressure: 24 (patient's normal was 10-14) on 27Aug2021; Rheumatoid lab tests: normal on Jul2021; magnetic resonance imaging (MRI) spinal: bulges spondylosis, subcentimeter csf cyst and facet degeneration Disc bulge. Foramen narrowing on 12Sep2021; Hip and Knees X-rays: normal on 28Jun2021. The patient had an emergency room visit for events left eye central vision loss, back pain, hip and knees pain. Therapeutic measures were taken as a result of all events, included: Avastin 1.25mg Eye injection for left eye central vision loss; CT, MRI Physical medicines, ortho referral, oral medicines for pain. The outcome of events left eye central vision loss, Back pain, Hip and Knees pain and limping right leg were not recovered. The outcome of event blurred vision was unknown. The case was reported as serious due to medically significant and disability condition.  Follow-up attempts completed. No further information expected.; Sender's Comments: Based on the information currently available, a possible contributory role of the suspect vaccine BNT162B2 or comirnarty in triggering the onset of central tunnel vision , arthralgia and back pain cannot be excluded. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.,Linked Report(s) : US-PFIZER INC-202101252495 same patient/drug, different dose/AE