Sex: F
Vaccine: COVID19
Symptoms: Gastrointestinal disorder, Gluten sensitivity, Hypersensitivity, Oropharyngeal discomfort, Paraesthesia
Clinical narrative: she had a hive on her back; was extremely uncomfortable; you could hear that her voice is different; digestive issue; gluten allergy; allergic reaction; her eyes started to itch; she had uncomfortable diarrhea; but this time her eyes started to tingle; her throat felt strange; her stomach has not felt terrific/stomach started to feel unhappy before this occurrence/stomach problem; This is a spontaneous report from a contactable consumer (patient herself). A 74-year-old female patient received BNT162B2 (Pfizer-BioNTech COVID-19 mRNA vaccine), dose 1 via an unspecified route of administration on Mar2021 (Batch/Lot Number: EN6204) as 1ST DOSE, SINGLE DOSE for COVID-19 immunisation. Medical history included history of celiac, gluten intolerance and anaphylaxis previously. There were no concomitant medications. The patient previously took EPIPEN on unspecified dates. Patient was put in the category of persons who have had anaphylactic episodes and so she was kept for observation for 30 minutes following the vaccine. She is in the category of someone who has had multiple, clarified to having 3, anaphylactic episodes previously. So she was watched very carefully after her first COVID vaccine and she did not have a reaction. However, she also has celiac and a gluten intolerance. Since the COVID vaccine shot on Mar2021, her stomach started to feel unhappy, acting like she was eating incorrectly, her stomach has not felt terrific, that was the best way that she can say what she was experiencing. The past Sunday from the time of reporting on 14Mar2021, she may have eaten something that disagreed with her. She is extremely careful about what she eats and Sunday, 14Mar2021, she had a chicken breast and ate a normal dinner. At 15Mar2021 04:00 AM, she had uncomfortable diarrhea, but this time her eyes started to tingle, her eyes started to itch, her throat felt strange. She thought this was not good, she had digestive issues which she thought might be related to her gluten allergy. This is always what happens in the beginning of her severe allergic reactions. It always starts with diarrhea, her eyes tingle and then she gets a sensation in the upper part of her throat. She said it eventually led to what felt like the onset of an allergic reaction. Her doctor has approved a combination of over the counter medication so that she doesn't have to use her EpiPen and prednisone that she has had for years which stops the reaction and it has worked incredibly well. The over the counter combination is a combination of prednisone, diphenhydramine (BENADRYL) and cimetidine (TAGAMET). She got this combination one time in the emergency room previously through an IV and it works. She took the combination which helped but the diarrhea and the stomach problems continued so that night she put herself on a liquid broth diet and and Jell-o to give her colon a break (treated it with broth and Jell-o). Last night, 16Mar2021, she was tired of that so she made a plain omelet. Again, at 17Mar2021 04:00 am in the morning, the same thing happened. She woke up and had diarrhea and was extremely uncomfortable. Her eyes started to tingle. However, this time she is sure she had a hive on her back, the top of  her throat started to feel strange. So she took the combination mentioned above again but took 2 prednisone although she usually takes 1, which has stopped some of the side effects but her stomach is the same even though there is not much in there. For about 3 hours she had the constant discomfort of diarrhea. Right now she can tell that her back is itchy although she can't see it because she lives alone. She can tell that there is a difference in her throat, it is not swelling, but she doesn't know how to explain it. If you knew her then you could hear that her voice is different. She says that she was calling Pfizer before she calls her doctor, but she will call him after this. She wants the second dose of the COVID vaccine so badly but she doesn't know if this is associated with the COVID vaccine. More or less she is looking for a clearing house since she is in the category of an anaphylactic episode. She hasn't had anymore allergic reaction or reactions for a long time like what she had experienced on Sunday and at the day of report. She says that she doesn't want to get emotional about this. Her next dose is scheduled for 26Mar2021. She thinks that her kids will freak out if they think she can't have the second shot. It is important to make clear that she is not someone who is angling to not take the second shot, she really wants it. She wanted to know if what she has experienced has been reported after receiving the first COVID vaccine. She knows it is unusual that she takes that three medication combination and she doesn't advise others to take that. She had a reaction a few years ago and when her late husband took her to the emergency room she usually just uses her EpiPen but this was pretty advanced and her throat hadn't behaved properly. She was hooked to 3 different IVs and she asked what they were and she was told it was a steroid, something comparable to diphenhydramine (BENADRYL, Jan2022 and lot number: 1741027), and the cimetidine (TAGAMET, lot number: 202947 and expiry date: AUG2022) which acts as a catalyst. She says that this combination has been approved by her doctor so she takes it wherever she goes. She hasn't had to have a shot of her EpiPen or go to emergency room in a while. She doesn't tell anyone else to take that combination, believe her, but for her it works. She must say, she is still feeling uncomfortable. She has no idea when she can see the doctor so she thinks that she would prefer to be able to talk to the medical information people if that was okay. The outcome of the events was unknown.