chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 12.0
Sex: F
Vaccine: HEP
Symptoms: Vomiting
Clinical narrative: The pt developed a rash and tightness in chest 1 hour post vax. Taken to ER the following day. The pt continued to complain of tightness in chest, dizziness, back ache, nausea with sporadic vomiting. Seen in ER 2 times.
Age: 50.0
Sex: M
Vaccine: TD, VARCEL
Symptoms: Hypersensitivity, Injection site swelling, Pyrexia
Clinical narrative: Pt had a large amount of swelling at the injection site and had a high temperature for 7 days. Reported by patient.
Age: 9.0
Sex: F
Vaccine: DT, HEP, HEPA, IPV, MMR
Symptoms: Erythema, Oedema
Clinical narrative: Pt had redness and swelling about 2" in area. Treated with cool packs.
Age: 1.25
Sex: M
Vaccine: DTAP, HIBV, IPV
Symptoms: Urticaria
Clinical narrative: Pt developed a urticarial rash.
Age: 1.38
Sex: F
Vaccine: DTAP, HIBV, IPV, MMR, VARCEL
Symptoms: Rash
Clinical narrative: Pt had a fine light rash on chest, arms and feet.
Age: 1.4
Sex: F
Vaccine: DTAP, HIBV, IPV
Symptoms: Urticaria
Clinical narrative: Pt went to ER on the night of the vaccination with urticaria (over total body). Treated and responded to Benadryl.
Age: 1.25
Sex: M
Vaccine: DTAP, HEP, HIBV
Symptoms: Febrile convulsion, Shock
Clinical narrative: Mom states that child went into shock and fever and had a seizure less than 24 hours, post vax. This was not the 1st seizure the child has had. Called ER and was told they did not feel it was a reaction to the vaccines, that it was probably just another febrile seizure.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Injection site erythema, Pruritus, Urticaria
Clinical narrative: At 10:30 pt had localized reaction at varicella injection site, within 1 minute of injection. Child complained of itching and had a 1cm papule/hive with itching and redness observed. Hive increased to 1.5cm with no other reactions noted. Ice was applied, 25mg Diphenhydramine HCL, Benadryl PO given. After 45 minutes, hives decreased to less than 1/2cm and no other reaction noted.
Age: 2.0
Sex: F
Vaccine: DTAP, HIBV, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Urticaria
Clinical narrative: Pt had a localized reaction to varicella, observed within 5 minutes, post vax, with redness and 1/2cm papule/hive at injection site, no itching and no other reaction observed. Diphenhydramine HCL/Benadryl (dye-free). Child was observed for 45 minutes and released. No other reactions noted, redness and hives decreased in size.
Age: 9.0
Sex: F
Vaccine: HEP, VARCEL
Symptoms: Injection site erythema, Pruritus, Urticaria
Clinical narrative: At 10:40, pt had a localized reaction at the varicella injection site. Pt complained of 4cm papule/hive and redness with itching, no other reaction observed. Ice was applied and 2 tsp of Diphenhydramine HCL/Benadryl PO was given. Child was observed for 45 minutes. Papule decreased from 2cm to lest than 1/2cm with no apparent reactions or distress.
Age: 34.0
Sex: F
Vaccine: HEP, MMR, TD
Symptoms: Dizziness, Dyspnoea, Injection site erythema, Injection site induration, Injection site swelling
Clinical narrative: Within 15 minutes, post vax, pt reported feeling light-headed and began to have SOB. She then noticed her right arm was red, swollen and hot to touch. She described her arm swelling as being about as big as an orange in diameter and approx. 1 1/2" induration. She states there was a small white circle at actual injection site. Pt took Benadryl and rested lying down for 15-20 minutes and then felt fine. Swelling and redness went away on 8/27/00.
Age: 34.0
Sex: F
Vaccine: HEP, MMR, TD
Symptoms: Injection site warmth
Clinical narrative: Within 15 minutes, post vax, pt reported feeling light-headed and began to have SOB. She then noticed her right arm was red, swollen and hot to touch. She described her arm swelling as being about as big as an orange in diameter and approx. 1 1/2" induration. She states there was a small white circle at actual injection site. Pt took Benadryl and rested lying down for 15-20 minutes and then felt fine. Swelling and redness went away on 8/27/00.
Age: 1.06
Sex: M
Vaccine: DTAP, HIBV, MMR, VARCEL
Symptoms: Pyrexia, Rash
Clinical narrative: Pt had a fever and rash. Mother returned to clinic with sibling and patient at a later date. Patient had recovered.
Age: 1.25
Sex: F
Vaccine: DTAP
Symptoms: Injection site erythema, Injection site induration, Injection site warmth
Clinical narrative: Pt had erythema, induration and warmth at injection site. No pain. No fever (99.1F) Pt was treated with Keflex since extensive and very warm.
Age: 42.0
Sex: F
Vaccine: TD
Symptoms: Fatigue, Pyrexia, Rash macular
Clinical narrative: On 9/1/00, complained of fatigue, chills and temperature of 100.7F. Took Tylenol at 20:15. Temperature was 100.3F. On 9/2/00, complained of red "blotches from head to toe" through 9/13/00 PM. All symptoms resolved on 9/3/00 PM.
Age: 0.3
Sex: F
Vaccine: DTAP, HIBV, IPV
Symptoms: Rash
Clinical narrative: One day, post vax, pt developed a rash on her face and legs of little, fine bumps. The rash on her face began to disappear after 1 week.
Age: 0.25
Sex: F
Vaccine: DTAP, HBHEPB, IPV
Symptoms: Pyrexia
Clinical narrative: Mother states child ran a 102.6F temperature throughout the evening and night. Mom took child to ER and was told the DTAP was the cause of the temperature. The next day she took child to pediatrician, who says the temperature was not from the shot. Temperature broke the next day.
Age: 3.0
Sex: F
Vaccine: DTAP, HIBV, VARCEL
Symptoms: Pruritus, Pyrexia, Rash papular
Clinical narrative: Macular/papular/vesicular lesions began on 9/5/00 in the evening with a temperature of 101.5F by mom's report. Lesions observed by RN, noted on face, arms, legs and perineal area in access of 100 lesions. Child itching. On 9/6/00, telephone call to mom; no change in appearance of lesions, afebrile, no pustules or itching.
Age: 4.0
Sex: F
Vaccine: VARCEL
Symptoms: Blister, Pruritus
Clinical narrative: Vesicles erupted on 9/14/00 on face, back and stomach followed course of disease and more erupting for 4 days, originally. Now crusted. No fever. Itchy. Treated with oatmeal baths and Benadryl at home until all are crusted.
Age: 44.0
Sex: M
Vaccine: LYME
Symptoms: Fatigue, Pain in extremity
Clinical narrative: In 2/99 and in 3/99, the pt received his first and second dose of Lymerix. One month subsequent to the second dose, in 4/99, he developed chronic foot pain with fatigue, which was considered by the reporter to be severely debilitating. A Rheumatology consultation (results not known) and labs (results not known) were obtained. The pt was treated with NSAID's and prednisone.  This case is considered serious as the pt's symptoms are considered to be permanently disabling.   As of 9/21/00, the reporter has difficulty controlling the pt's symptoms. Per follow-up dated 1/17/01, information received from the vaccine provider indicated that the events are ongoing and the pt remains disabled.
Age: 12.0
Sex: F
Vaccine: LYME
Symptoms: Arthralgia, Fatigue, Headache, Joint swelling, Laboratory test abnormal
Clinical narrative: Report 2000027467-1 describes swelling of the knees and achy joints in a 12 year old female who received two injections of Lyme vaccine during a clinical trial protocol 030, center 016, pt id 3163. This report was received by the pt's attorney and has been confirmed by the study investigative site.   According to the mother, she was contacted by the investigator site to have her two children participate in the SKB pediatric study because "one of her children had Lyme disease previously and the other did not." the pt was a participant in clinical trial protocol 022 and was a placebo cross-over subject in clinical trial 030. She received doses of Lyme vaccine on 4/17/00 and 5/15/00. According to the attorney, the pt experienced "some swelling and headaches that lasted a while" after the first injection. According to the study investigator site, the pt "reported mild to moderate symptoms on her diary card." Per the attorney, the pt's mother questioned the investigative site as to whether or not the symptoms were related and whether or not her daughter should get the second shot. Per the mother "the doctor's told her that there was not problem and told her that it was perfectly okay for the children to go forward with he second shot." Since the second shot, her daughter has had "serious problems." The pt is extremely fatigued, sleeping ten hours a day and taking three to four hour naps daily. She has had swelling in her knees and aches and pains throughout her body. According to the investigative site, they received the pt's second safety postcard on 7/10/00 where it was reported that the pt had been experiencing tiredness, achy joints (knees) and headaches all continuing form 6/11/00. At the mother's request, the pt has since tested HLA-DR4 positive on 8/29/00. At the time of this report, the events are ongoing and the pt has been referred to a rheumatologist.
Age: 12.0
Sex: F
Vaccine: LYME
Symptoms: Pain, Somnolence
Clinical narrative: Report 2000027467-1 describes swelling of the knees and achy joints in a 12 year old female who received two injections of Lyme vaccine during a clinical trial protocol 030, center 016, pt id 3163. This report was received by the pt's attorney and has been confirmed by the study investigative site.   According to the mother, she was contacted by the investigator site to have her two children participate in the SKB pediatric study because "one of her children had Lyme disease previously and the other did not." the pt was a participant in clinical trial protocol 022 and was a placebo cross-over subject in clinical trial 030. She received doses of Lyme vaccine on 4/17/00 and 5/15/00. According to the attorney, the pt experienced "some swelling and headaches that lasted a while" after the first injection. According to the study investigator site, the pt "reported mild to moderate symptoms on her diary card." Per the attorney, the pt's mother questioned the investigative site as to whether or not the symptoms were related and whether or not her daughter should get the second shot. Per the mother "the doctor's told her that there was not problem and told her that it was perfectly okay for the children to go forward with he second shot." Since the second shot, her daughter has had "serious problems." The pt is extremely fatigued, sleeping ten hours a day and taking three to four hour naps daily. She has had swelling in her knees and aches and pains throughout her body. According to the investigative site, they received the pt's second safety postcard on 7/10/00 where it was reported that the pt had been experiencing tiredness, achy joints (knees) and headaches all continuing form 6/11/00. At the mother's request, the pt has since tested HLA-DR4 positive on 8/29/00. At the time of this report, the events are ongoing and the pt has been referred to a rheumatologist.
Age: 0.2
Sex: F
Vaccine: DTAP, HBHEPB, IPV
Symptoms: Cough, Cyanosis, Dyspnoea, Infection
Clinical narrative: On 9/7/00, the pt experienced coughing, could not breath. The pt went to the ER on 9/10/00 with coughing and blueness. The pt was admitted with a positive test for pertussis.
Age: 53.0
Sex: M
Vaccine: LYME
Symptoms: Antinuclear antibody positive, Arthralgia, Clumsiness, Laboratory test abnormal, Somatoform disorder
Clinical narrative: As of the time of this report this pt has had a six month history of psychomotor retardation, clumsiness, lack of coordination, joint pain, migratory arthralgias.
Age: 3.0
Sex: F
Vaccine: PNC
Symptoms: Urticaria
Clinical narrative: Urticaria onset occurred 12 hours post vax. Prescribed antihistamine and cortisone for 5 days.
Age: 1.3
Sex: F
Vaccine: DTAP, HIBV, MMR, PNC
Symptoms: Injection site hypersensitivity
Clinical narrative: Erythema around injection site 15 minutes post administration. No hives/induration/serum opsonic activity. Benadryl elixir 12.5 mg given.
Age: 1.0
Sex: M
Vaccine: PNC, VARCEL
Symptoms: Coordination abnormal
Clinical narrative: Three days post varicella vax, this pt developed ataxia that lasted seven days.
Age: 0.3
Sex: F
Vaccine: DTAP, HIBV, IPV, PNC
Symptoms: Agitation, Injection site hypersensitivity, Injection site oedema, Injection site pain
Clinical narrative: This pt experienced right thigh red and swollen and tender. Onset began within a few hours of Hib and Prevnar (right thigh). Very fussy, crying infant.
Age: 0.75
Sex: F
Vaccine: PNC
Symptoms: Urticaria
Clinical narrative: Hives all over leg in which vax was given. Resolved spontaneously over some hours.
Age: 0.78
Sex: M
Vaccine: PNC, PNC
Symptoms: Urticaria
Clinical narrative: Urticaria 24 hours post administration of Prevnar. Began Benadryl 1/2 teaspoon every four ours as needed.
Age: 2.0
Sex: M
Vaccine: DTAP, HIBV, MMR, PNC
Symptoms: Pyrexia
Clinical narrative: One and one half days post vax, this pt developed 105 degree temperature. Mother treated with Tylenol and Motrin to control temperature.
Age: 1.08
Sex: U
Vaccine: DTAP, HIBV, IPV, MMR, PNC, VARCEL
Symptoms: Convulsion, Drooling, Eye disorder, Vomiting
Clinical narrative: This child experienced a seizure on Friday at 1:00 AM, seizing for approximately one hour, drooling, eyes deviated to the right. Seizure preceded by vomiting. No fever.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Rash papular
Clinical narrative: 2cm elongated erythematous papular lesion on left thigh, non-painful at injection site. Sister with same response, occurred 15 days, post vax. No systemic symptoms although pox lesion also noted on face and arm, several days later.
Age: 12.0
Sex: M
Vaccine: HEP
Symptoms: Pyrexia, Vomiting
Clinical narrative: 6 hours post vax, the pt experienced vomiting, which lasted into the evening. He spiked a fever of 101.0. Mom called the pediatrician to report illness.
Age: 1.25
Sex: F
Vaccine: DTAP, HIBV, IPV
Symptoms: Injection site erythema, Injection site induration
Clinical narrative: Rt thigh area red and indurated with 3-4cm area affected, within 24 hour, post vax.
Age: 0.5
Sex: F
Vaccine: DTAP, HEP, HIBV
Symptoms: Erythema, Injection site erythema, Injection site induration, Irritability
Clinical narrative: Fussy, post vax, that afternoon. No fever. Mom call on 8/17/00 and said that area was a little red. Seen in office on 8/17/00 and right thigh  had a 3cm X 3 1/2cm erythematous area with very mild injection site induration.
Age: 11.0
Sex: M
Vaccine: HEP
Symptoms: Hyperhidrosis, Hypotension, Pallor
Clinical narrative: At 10:00, client became pale, diaphoretic, decreased BP. Used ammonia inhalant. He remained conscious; reclined. Parent notified and gave food and fluids at 10:50 and discharged to home. Transported via parent. Per parents, client has a history of fainting with needles.
Age: 2.0
Sex: M
Vaccine: DTAP
Symptoms: Injection site swelling
Clinical narrative: Swelling on entire right leg from above knee to top of thigh, first noted on 8/29/00. Mother gave ibuprofen and applied ice. Swelling still present on 8/30/00. Pt referred to doctor for evaluation.
Age: 10.0
Sex: F
Vaccine: HEP
Symptoms: Unevaluable event
Clinical narrative: At 13:10, client reportedly fell out of desk seat onto floor. No physical injury noted. BP was stable. Observed for 30 minutes. Discharged to home accompanied by mother. She was advised to seek medical care if needed.
Age: 11.0
Sex: M
Vaccine: HEP
Symptoms: Erythema, Injection site erythema
Clinical narrative: Pt received Hep-B to left arm at school. Noticed redness to injection site, within 30 minutes and also redness to face and a reddened area to chest. No elevated hives, no respiratory difficulties. BP and pulse stable, declined Benadryl by father and discharged with father, 30 minutes later. Called pt at home on 8/29/00 and grandmother stated "pt was not seen by doctor, he is doing fine and no complaints.
Age: 2.0
Sex: M
Vaccine: DT, HIBV, VARCEL
Symptoms: Dyspnoea, Heart rate increased
Clinical narrative: Six hours post vax, the pt developed heart racing, difficulty breathing. Taken to ER and treated with Triaminic and Motrin.
Age: 18.0
Sex: F
Vaccine: HEP
Symptoms: Dizziness, Fatigue, Nausea
Clinical narrative: Phone contact from pt's mom at 16:45 on 9/15/00. She verbalized that pt received Hep-B at 10:30 on 9/14/00 and around 20:30 that night, she said pt called her at work complaining of dizziness, nausea and fatigue. She advised her to go to bed and rest. She said the pt said she fell asleep around midnight. Mom said pt only complained of fatigue the next day and denies any further problems.
Age: 1.5
Sex: M
Vaccine: DTAP, HIBV, IPV, MMR, VARCEL
Symptoms: Erythema, Oedema peripheral, Rash
Clinical narrative: When mother put child in bathtub this AM (6:28), she noted puffiness of hand and feet and redness of feet. There was a rash on legs and arms.
Age: 4.0
Sex: M
Vaccine: DTAP, HBHEPB, IPV, MMR
Symptoms: Injection site erythema, Injection site inflammation, Injection site warmth, Urticaria
Clinical narrative: Pt's left upper arm was warm, inflamed, red and welt-like around entire circumference.
Age: 1.25
Sex: F
Vaccine: DTAP, HIBV, MMR
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: Within 5-10 minutes, post vax, pt developed raised area (pencil eraser sized), redness and warmth at site of MMR. Pt's physician was called and received orders to give Epinephrine if redness got larger than 1/2 dollar size. This was the case and Epinephrine was given SC in left thigh. No further reaction was noted for approx. 15-20 minutes following Epinephrine (Monarch/02709/SC/LL/0 previously). Phoned daycare the following day, 8/15/00, and personnel stated she was doing well and symptoms better.
Age: 33.0
Sex: F
Vaccine: MMR
Symptoms: Pain
Clinical narrative: Client state almost immediately experienced left hip pain, no swelling. She sought medical attention on 09/11 and was placed on Darvocet. On 9/12 she conveyed to the medical personnel that this medication was not helping. She was then placed on 600 mg Ibuprofen. Dosage was increased to 800 mg on 09/15. She states only minimal soreness remains as of 09/18.
Age: 49.0
Sex: F
Vaccine: TD
Symptoms: Chills, Cough, Dizziness, Lethargy, Lymphadenopathy
Clinical narrative: Within one hour post vax, this pt reports feeling dizzy, lethargic, developed fever 5 hours later, chills swollen glands in neck, stiffness of neck, aches, body pains, cough, mucous lasting 2 weeks. Reports continues to have stiffness in neck almost one month post vax. No treatment per client.
Age: 49.0
Sex: F
Vaccine: TD
Symptoms: Musculoskeletal stiffness, Nasal congestion, Pain, Pyrexia
Clinical narrative: Within one hour post vax, this pt reports feeling dizzy, lethargic, developed fever 5 hours later, chills swollen glands in neck, stiffness of neck, aches, body pains, cough, mucous lasting 2 weeks. Reports continues to have stiffness in neck almost one month post vax. No treatment per client.
Age: 3.0
Sex: F
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: Pyrexia, Rash
Clinical narrative: Two weeks post vax, "fever and flat rash on body that comes and goes." Fever lasted 243 hours. Rash continued for 3 days. No other symptoms.
Age: 12.0
Sex: M
Vaccine: HEP, MMR, TD
Symptoms: Erythema, Eyelid oedema, Pruritus
Clinical narrative: Caller reports that client's face turned red, eyelids swollen, itching of face and arms. Began approximately 15 hours post vax. No fever. Was given antihistamine by a physician who was a neighbor with effect.
Age: 12.0
Sex: M
Vaccine: HEP
Symptoms: Dry throat, Influenza like illness, Malaise, Myalgia, Pyrexia
Clinical narrative: Twenty-four hours post vax, this pt developed fever of 100 F. No local reaction. Flu-like symptoms have continued and progressed - malaise, scratchy throat, myalgia.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Cellulitis, Erythema, Pyrexia, Skin nodule
Clinical narrative: Redness and induration of the left forearm. Temperature. Cellulitis.
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site hypersensitivity, Injection site oedema, Injection site pain, Pyrexia
Clinical narrative: Reported by parent swelling and redness with fever of greater than 103 same day as the shot Redness over two thirds of upper arm. Some pain.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Redness and swelling over right deltoid area. Slight pain localized to deltoid area. Treat with warm compresses and observe for progression.
Age: 1.0
Sex: M
Vaccine: DTAP, HBHEPB, IPV, MMR
Symptoms: Pyrexia, Rash
Clinical narrative: Pt back in clinic day after IZ with rash over body; most prominent around MMR injection site. Fever of 101.4F. Medical impression: mild vaccine associated rash and fever. Called and spoke with grandmother on 9/20/00 AM and she reports child is afebrile and eating and acting fine but still with rash over body.
Age: 2.0
Sex: M
Vaccine: DTAP, HIBV
Symptoms: Dyskinesia, Eye movement disorder, Febrile convulsion, Opisthotonus, Upper respiratory tract infection
Clinical narrative: On 8/19/00 at 01:00, mom was sleeping with child when he awakened her with jerky movements of all extremities, head thrown back and eyes rolled back, lasting 5 minutes. EMS arrived and transported to ER. Temperature was 103.3F. Another episode of jerky movements when arrived at hospital, lasting 2-3 seconds. He was dx'd with febrile seizure and URI.
Age: 74.0
Sex: F
Vaccine: FLU3
Symptoms: Swelling face, Urticaria
Clinical narrative: Swelling of lips, hives on breast and within 36 hours, generalized hives. On 9/21/00, pt came in with above symptoms. Treated with Solu-Medrol and Benadryl.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Erythema multiforme
Clinical narrative: The pt experienced erythema multiforme - minor which began 6 days post vax.
Age: 1.9
Sex: M
Vaccine: DTAP, IPV, VARCEL
Symptoms: Injection site erythema, Injection site induration, Injection site swelling, Pyrexia
Clinical narrative: Swelling at site of injection, redness the size of a 50 cents piece, hard lump underneath and fever. Treated with Tylenol and Benadryl.
Age: 2.0
Sex: F
Vaccine: DTAP, HIBV, IPV, MMR
Symptoms: Chest X-ray abnormal, Convulsion, Pyrexia
Clinical narrative: Fever associated, generalized tonic/clonic seizure. Seen at ER and put on Zithromax due to mildly abnormal chest X-ray. No recurrence.
Age: 1.0
Sex: F
Vaccine: VARCEL
Symptoms: Muscular weakness, Paralysis
Clinical narrative: Varivax on 3/6/00. On 3/9/00 had brief episode of leg weakness. On 3/15 seen with leg weakness. Neurologist exam on 3/16/00; dx: periodic paralysis, resolved spontaneously.
Age: 1.25
Sex: M
Vaccine: DTAP, MMR
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: Pt's arm was red, hot and swollen.
Age: 27.0
Sex: F
Vaccine: HEP
Symptoms: Feeling cold, Headache, Injection site pain, Lethargy
Clinical narrative: Immediate pain at injection site followed in 2 hours by, chilly feeling, headaches and lethargy. She took 1 dose of Tylenol. Complete recovery within 12 hours. No rash or wheals.
Age: 8.0
Sex: M
Vaccine: DTAP, OPV, VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: Had varicella injection on 5/6/97. Broke out with chickenpox on 9/17/00. Came to office on 9/18/00 and was dx'd with chickenpox. Presently has chickenpox.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: Fatigue, Injection site induration, Injection site pain, Injection site swelling, Irritability
Clinical narrative: Pt with severe swelling and tenderness of right thigh with 6cm X 6cm swollen, indurated area in right thigh. Pt very fussy X 3 hours with onset about 3 hours, post vax. Increased tiredness for 2 days.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: Injection site induration, Irritability
Clinical narrative: Moderate fussiness X 2 hours with onset 4 hours, post vax. Pt checked about 5 hours, post vax, and without increase of temperature and looked well. On recheck, 1 day, post vax, pt was smiling and alert with 3, 1/2cm indurated areas at vaccine sites.
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Rash papular, Rash pustular
Clinical narrative: The pt received the Varivax vaccine #1 and MMR #1 on 8/24/00. The pt developed papulo-pustular lesions (21) on the arms, trunk and legs on 9/15/00. He had no fever.
Age: 1.0
Sex: M
Vaccine: DTAP, HIBV, IPV, MMR
Symptoms: Erythema, Pruritus, Rash macular
Clinical narrative: On 9/20/00 at 10:45, mom called and stated that shots given yesterday and last night she noticed bumps on face but thought they were mosquito bites. This morning same size but child began scratching. Now bumps on face are large, red and about a quarter size. Child scratching and near eyes. Denied fever or bumps anywhere else. Told to go to ER of closest hospital now with shot card. Mom states she will go to ER and let doctor know child received shots yesterday and will bring shot card with her.
Age: 29.0
Sex: F
Vaccine: HEP
Symptoms: Lymphadenopathy
Clinical narrative: Noted enlarged lymph node about right clavicle on anterior chest wall of a few days duration following hep vaccine #2 and again after hep vaccine #3.
Age: 17.0
Sex: M
Vaccine: MMR
Symptoms: Hypersensitivity, Pruritus, Rash, Urticaria
Clinical narrative: On 5/26/00, broke out in a rash and itched all over. Rash and itching got worse. Mom took pt to the ER on 5/28/00 and doctor prescribed prednisone dose pack for 6 days and Benadryl, which he took. Pt stopped taking Ceclor on 5/26/00. Pt no better on 5/30/00, so mom took him to MD. MD there thought rash, itching and hives were related to Ceclor allergy. Symptoms still present on 05/30/00.
Age: 33.0
Sex: M
Vaccine: TD
Symptoms: Headache, Injection site erythema, Injection site pain, Pain, Pyrexia
Clinical narrative: Pt called to report that on 9/14/00, he had a temperature of 101.5F, body aches, worst headache ever, sore arm and redness at injection site. All resolved except sore arm, he stated on 9/15/00.
Age: 2.0
Sex: M
Vaccine: DTAP, HIBV, IPV, VARCEL
Symptoms: Injection site erythema, Injection site induration
Clinical narrative: 1 day, post vax, left thigh developed 13cm induration with 6cm X 7 1/2cm erythema around vaccine site. Non-tender; no fever. Treated with supportive care.
Age: 3.9
Sex: M
Vaccine: DTAP, OPV
Symptoms: Abnormal behaviour, Autism, Dementia
Clinical narrative: Then 3 year old with PDD, mom feels that she noted a regression in behavior for 6 weeks after immunization.
Age: 3.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Asthenia, Bradycardia, Coma, Cyanosis, Dysphonia
Clinical narrative: Per mom, pt fainted and hit his head on the floor about 2 minutes, post vax. I picked him up and looked at his head and face, at that point I saw that his eyes were rolling back in his head and his lips were turning blue. We layed him on the bed and there was no response from him to my voice. The nurse then asked me what to do? What I wanted to do about patient? The nurse then left the room to get an ammonia stick, to wave under patient's nose. We got no response from him. While she was gone, I continued to talk to him and try to get him to respond. I listened to his chest and his heartbeat was slowing and his lips were still blue. The nurse then left again and went to get another nurse. The both came back. The ammonia was still not working. Patient finally said "mommy" in a very hoarse voice. I then ask for some water for patient to drink. I felt patient and he was burning up. I removed his shirt. When the nurse returned, I had patient take a drink. At that time, I saw that patient's tongue was enlarged and discolored. We put some cold wet paper towels on his head and had him drink some more water. After getting the water down him and the wet paper towels on him, he started to cool down. Patient then started to come around. Patient weighs 27 lbs and his blood pressure was 90/60, when the nurses took it at about 9:20. This all started at about 9:02 and it took about 25 minutes, to revive him to where we could leave. He still acted weak for about 2-3 hours. On another note, I feel as if the nurses at the facility, did not really know what they were doing. My doctor said that this was a severe allergic reaction to the shots and the nurses have said that it was only normal behavior to the shots and that all children do this.
Age: 3.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Eye movement disorder, Feeling hot, Hypersensitivity, Hypotension, Syncope
Clinical narrative: Per mom, pt fainted and hit his head on the floor about 2 minutes, post vax. I picked him up and looked at his head and face, at that point I saw that his eyes were rolling back in his head and his lips were turning blue. We layed him on the bed and there was no response from him to my voice. The nurse then asked me what to do? What I wanted to do about patient? The nurse then left the room to get an ammonia stick, to wave under patient's nose. We got no response from him. While she was gone, I continued to talk to him and try to get him to respond. I listened to his chest and his heartbeat was slowing and his lips were still blue. The nurse then left again and went to get another nurse. The both came back. The ammonia was still not working. Patient finally said "mommy" in a very hoarse voice. I then ask for some water for patient to drink. I felt patient and he was burning up. I removed his shirt. When the nurse returned, I had patient take a drink. At that time, I saw that patient's tongue was enlarged and discolored. We put some cold wet paper towels on his head and had him drink some more water. After getting the water down him and the wet paper towels on him, he started to cool down. Patient then started to come around. Patient weighs 27 lbs and his blood pressure was 90/60, when the nurses took it at about 9:20. This all started at about 9:02 and it took about 25 minutes, to revive him to where we could leave. He still acted weak for about 2-3 hours. On another note, I feel as if the nurses at the facility, did not really know what they were doing. My doctor said that this was a severe allergic reaction to the shots and the nurses have said that it was only normal behavior to the shots and that all children do this.
Age: 3.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Tongue discolouration, Tongue oedema
Clinical narrative: Per mom, pt fainted and hit his head on the floor about 2 minutes, post vax. I picked him up and looked at his head and face, at that point I saw that his eyes were rolling back in his head and his lips were turning blue. We layed him on the bed and there was no response from him to my voice. The nurse then asked me what to do? What I wanted to do about patient? The nurse then left the room to get an ammonia stick, to wave under patient's nose. We got no response from him. While she was gone, I continued to talk to him and try to get him to respond. I listened to his chest and his heartbeat was slowing and his lips were still blue. The nurse then left again and went to get another nurse. The both came back. The ammonia was still not working. Patient finally said "mommy" in a very hoarse voice. I then ask for some water for patient to drink. I felt patient and he was burning up. I removed his shirt. When the nurse returned, I had patient take a drink. At that time, I saw that patient's tongue was enlarged and discolored. We put some cold wet paper towels on his head and had him drink some more water. After getting the water down him and the wet paper towels on him, he started to cool down. Patient then started to come around. Patient weighs 27 lbs and his blood pressure was 90/60, when the nurses took it at about 9:20. This all started at about 9:02 and it took about 25 minutes, to revive him to where we could leave. He still acted weak for about 2-3 hours. On another note, I feel as if the nurses at the facility, did not really know what they were doing. My doctor said that this was a severe allergic reaction to the shots and the nurses have said that it was only normal behavior to the shots and that all children do this.
Age: 3.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Hypotension, Syncope
Clinical narrative: Per mom, pt fainted and hit his head on the floor about 2 minutes, post vax. I picked him up and looked at his head and face, at that point I saw that his eyes were rolling back in his head and his lips were turning blue. We layed him on the bed and there was no response from him to my voice. The nurse then asked me what to do? What I wanted to do about patient? The nurse then left the room to get an ammonia stick, to wave under patient's nose. We got no response from him. While she was gone, I continued to talk to him and try to get him to respond. I listened to his chest and his heartbeat was slowing and his lips were still blue. The nurse then left again and went to get another nurse. The both came back. The ammonia was still not working. Patient finally said "mommy" in a very hoarse voice. I then ask for some water for patient to drink. I felt patient and he was burning up. I removed his shirt. When the nurse returned, I had patient take a drink. At that time, I saw that patient's tongue was enlarged and discolored. We put some cold wet paper towels on his head and had him drink some more water. After getting the water down him and the wet paper towels on him, he started to cool down. Patient then started to come around. Patient weighs 27 lbs and his blood pressure was 90/60, when the nurses took it at about 9:20. This all started at about 9:02 and it took about 25 minutes, to revive him to where we could leave. He still acted weak for about 2-3 hours. On another note, I feel as if the nurses at the facility, did not really know what they were doing. My doctor said that this was a severe allergic reaction to the shots and the nurses have said that it was only normal behavior to the shots and that all children do this.
Age: 3.0
Sex: F
Vaccine: HEPA, TYP
Symptoms: Swelling face, Tongue oedema, Urticaria
Clinical narrative: Pt presented with hives on face, stomach, arms and legs about 5 minutes, post vax. Swelling of lips and tongue were also present. Pt was given epinephrine and Benadryl.
Age: 13.0
Sex: F
Vaccine: TD
Symptoms: Blood pressure increased, Hypersensitivity, Injection site swelling, Pruritus, Tachycardia
Clinical narrative: Youth given TD on 9/15/00 and 7 minutes, post vax, she complained of itching at site. Site is erythematous about 10cm completely around and is slightly raised. No respiratory symptoms. BP 150/80; HR 92; Resp 18. Youth was given Benadryl IM in right deltoid. At 10:00 BP 124/70; HR 80; Resp 18. Youth states the itching has decreased and erythema is resolving.
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Arthralgia, Arthritis, Carpal tunnel syndrome, Hepatic enzyme abnormal, Joint swelling
Clinical narrative: 1st dose of Hep-B was on 5/26/00. 2nd dose of Hep-B was on 6/26/00 and within a few days, developed nausea, slight fever, then knee pain and swelling, tingling and pain and numbness of both hands. Severe joint pain. Was dx'd with acute arthritis, Reynaud's syndrome and carpal tunnel (severe).
Age: 40.0
Sex: F
Vaccine: HEP
Symptoms: Nausea, Paraesthesia, Pyrexia, Raynaud's phenomenon
Clinical narrative: 1st dose of Hep-B was on 5/26/00. 2nd dose of Hep-B was on 6/26/00 and within a few days, developed nausea, slight fever, then knee pain and swelling, tingling and pain and numbness of both hands. Severe joint pain. Was dx'd with acute arthritis, Reynaud's syndrome and carpal tunnel (severe).
Age: 1.75
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Rash
Clinical narrative: Several (30-50) lesions on upper body.
Age: 0.5
Sex: F
Vaccine: DTAP, HIBV, IPV
Symptoms: Injection site erythema
Clinical narrative: Approx. 10 minutes, post vax, pt developed large, reddened area which covered 1/2 the surface of her thigh.
Age: 43.0
Sex: F
Vaccine: RUB
Symptoms: Oedema peripheral
Clinical narrative: On 8/3/00 pt phoned with a complaint of swelling at ankles, knees and wrists. Pt saw PMD on 8/8/00 and at that time, swelling was resolving. Condition continued to improve and eventually resolved.
Age: 1.5
Sex: F
Vaccine: DTAP, HIBV, MMR
Symptoms: Injection site erythema
Clinical narrative: Pt's mom states that she didn't notice any redness until the evening of the day after she received vaccine. She had large, reddened, local reaction on her thigh.
Age: 0.2
Sex: M
Vaccine: DTAP, HIBV, IPV
Symptoms: Cold sweat, Crying, Cyanosis, Listless, Pallor
Clinical narrative: Crying, listless, pale and dusky around the mouth, skin cold and clammy and was drowsy. He was given warm bath then took bottle 30 minutes later. Acted like himself like himself, 2 hours later.
Age: 0.2
Sex: M
Vaccine: DTAP, HIBV, IPV
Symptoms: Somnolence
Clinical narrative: Crying, listless, pale and dusky around the mouth, skin cold and clammy and was drowsy. He was given warm bath then took bottle 30 minutes later. Acted like himself like himself, 2 hours later.
Age: 57.0
Sex: F
Vaccine: IPV, TD, YF
Symptoms: Pruritus, Rash
Clinical narrative: 4 days, post vax, pt developed rash on legs, very itchy.
Age: 4.0
Sex: F
Vaccine: VARCEL
Symptoms: Cerebral infarction, Hemiplegia
Clinical narrative: Information has been received from a published article titled Postlicensure Safety Surveillance for Varicella Vaccine concerning a female pt who two weeks post vax, developed hemiparesis with evidence from MRI of cerebral infarctions in the putamen and internal capsule. Her apparent cerebrovascular accident assumes particular importance after recent description of a significant association between natural chickenpox and subsequent ischemic strokes in children. It was noted that this report was received after preparation of this article. Upon medical review, it was determined that the pt's hemiparesis was an other medical event. No further information is available.
Age: 55.0
Sex: U
Vaccine: LYME, LYME, LYME, LYME
Symptoms: Arthralgia, Joint swelling, Vasodilation procedure
Clinical narrative: Within two days post vax, the pt had scalded feeling to hands, hands became swollen and painful; difficult to move fingers. Given anti-inflammatories by physician. Pt also had foot pain, headache, and nausea.
Age: 55.0
Sex: U
Vaccine: LYME, LYME, LYME, LYME
Symptoms: Headache, Hypokinesia, Infection, Nausea, Oedema peripheral
Clinical narrative: Within two days post vax, the pt had scalded feeling to hands, hands became swollen and painful; difficult to move fingers. Given anti-inflammatories by physician. Pt also had foot pain, headache, and nausea.
Age: 55.0
Sex: U
Vaccine: LYME, LYME, LYME, LYME
Symptoms: Pain
Clinical narrative: Within two days post vax, the pt had scalded feeling to hands, hands became swollen and painful; difficult to move fingers. Given anti-inflammatories by physician. Pt also had foot pain, headache, and nausea.
Age: 55.0
Sex: U
Vaccine: LYME, LYME, LYME, LYME
Symptoms: Headache, Hypokinesia, Laboratory test abnormal, Nausea, Oedema peripheral
Clinical narrative: Within two days post vax, the pt had scalded feeling to hands, hands became swollen and painful; difficult to move fingers. Given anti-inflammatories by physician. Pt also had foot pain, headache, and nausea.
Age: 55.0
Sex: U
Vaccine: LYME, LYME, LYME, LYME
Symptoms: Pain, Skin burning sensation
Clinical narrative: Within two days post vax, the pt had scalded feeling to hands, hands became swollen and painful; difficult to move fingers. Given anti-inflammatories by physician. Pt also had foot pain, headache, and nausea.
Age: 4.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Asthenia, Bradycardia, Coma, Cyanosis, Dysphonia
Clinical narrative: Child fainted, post vax. Easily aroused.
Age: 4.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Eye movement disorder, Feeling hot, Hypersensitivity, Hypotension, Syncope
Clinical narrative: Child fainted, post vax. Easily aroused.
Age: 4.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Tongue discolouration, Tongue oedema
Clinical narrative: Child fainted, post vax. Easily aroused.
Age: 4.0
Sex: M
Vaccine: HEPA, MMR, VARCEL, HEPA, MMR, VARCEL
Symptoms: Hypotension, Syncope
Clinical narrative: Child fainted, post vax. Easily aroused.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Alanine aminotransferase increased, Alkalosis, Blood albumin decreased, Blood amylase increased, Blood bilirubin increased
Clinical narrative: This pt received first two doses of hepatitis B vax in 1988. On 02/18/00, she received the third. Within the same month, she experienced an increase in her liver function tests and was then dxed with Epstein-Barr virus. Follow-up information indicated that approximately 20 days post vax, on 03/10, she developed nausea, vomiting, elevated liver enzymes, lymphadenopathy in her neck, and urticaria on her body. The pt was initially seen in the physician's office and later in the week, 03/10, she presented to the ER and was admitted to the hospital. Labs were conducted. The physician noted on her admission that there was a possibility that she had a sub-clinical hepatic reaction to the vax. At the time of hospitalization, the etiology was unclear. Gallbladder ultrasound, CT abdomen scan were all within nml limits. The biliary tree was not dilated. The gallbladder appears to be very small, however, contracted and contained small ill defined opacities which may represent biliary sludge of tiny gallbladder calculi. The spleen was mildly enlarged and show homogeneous attenuation. The pancreas, adrenal glands and kidneys are within nml limits. There is no evidence of free fluid in the pelvic cavity. The impression was top normal size liver, mild splenomegaly, small contracted gallbladder, probably secondary to cholecystitis. There are small faint opacities with the lumen of the gallbladder calculi. The remainder of the CT scan was unremarkable. According to the physician, this pt was febrile to 103.1 F in the past, but currently afebrile. Other vitals were unremarkable. Ear, nose and throat assessment showed slight icterus. Significant lymphadenopathy in the anterior cervical chains were noted in the neck exam. Heart, lungs, abdomen, and neurologic exam nml. Extremities had no edema but showed urticaria on face, neck, trunk and arms. The impression was elevated liver enzymes with lymphadenopathy and urticaria, the differential of this condition is long, however the physician believed the possibility of two concurrent conditions was likely. He reported mononucleosis with concurrent chemical dermatitis; subclinical hepatitis from clinical agent causing contact dermatitis or subclinical hepatitis from Hepatitis B vax, possible common bile duct obstruction, concurrent dermatitis. The plan was hydration and observation. The pt was discharged on 03/11. She was observed and 3rd set of liver enzymes was significantly improved but bilirubin was essentially unchanged. She feels well, is eating, somewhat nauseated, but not vomiting. She was discharged to bed rest and was restart Medrol Dosepak and follow up with physician on 03/13.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Gallbladder disorder, Haematocrit decreased, Haemoglobin decreased, Hepatic enzyme abnormal, Hepatic function abnormal
Clinical narrative: This pt received first two doses of hepatitis B vax in 1988. On 02/18/00, she received the third. Within the same month, she experienced an increase in her liver function tests and was then dxed with Epstein-Barr virus. Follow-up information indicated that approximately 20 days post vax, on 03/10, she developed nausea, vomiting, elevated liver enzymes, lymphadenopathy in her neck, and urticaria on her body. The pt was initially seen in the physician's office and later in the week, 03/10, she presented to the ER and was admitted to the hospital. Labs were conducted. The physician noted on her admission that there was a possibility that she had a sub-clinical hepatic reaction to the vax. At the time of hospitalization, the etiology was unclear. Gallbladder ultrasound, CT abdomen scan were all within nml limits. The biliary tree was not dilated. The gallbladder appears to be very small, however, contracted and contained small ill defined opacities which may represent biliary sludge of tiny gallbladder calculi. The spleen was mildly enlarged and show homogeneous attenuation. The pancreas, adrenal glands and kidneys are within nml limits. There is no evidence of free fluid in the pelvic cavity. The impression was top normal size liver, mild splenomegaly, small contracted gallbladder, probably secondary to cholecystitis. There are small faint opacities with the lumen of the gallbladder calculi. The remainder of the CT scan was unremarkable. According to the physician, this pt was febrile to 103.1 F in the past, but currently afebrile. Other vitals were unremarkable. Ear, nose and throat assessment showed slight icterus. Significant lymphadenopathy in the anterior cervical chains were noted in the neck exam. Heart, lungs, abdomen, and neurologic exam nml. Extremities had no edema but showed urticaria on face, neck, trunk and arms. The impression was elevated liver enzymes with lymphadenopathy and urticaria, the differential of this condition is long, however the physician believed the possibility of two concurrent conditions was likely. He reported mononucleosis with concurrent chemical dermatitis; subclinical hepatitis from clinical agent causing contact dermatitis or subclinical hepatitis from Hepatitis B vax, possible common bile duct obstruction, concurrent dermatitis. The plan was hydration and observation. The pt was discharged on 03/11. She was observed and 3rd set of liver enzymes was significantly improved but bilirubin was essentially unchanged. She feels well, is eating, somewhat nauseated, but not vomiting. She was discharged to bed rest and was restart Medrol Dosepak and follow up with physician on 03/13.
Age: 37.0
Sex: F
Vaccine: HEP
Symptoms: Infection, Jaundice, Laboratory test abnormal, Lymphadenopathy, Lymphopenia
Clinical narrative: This pt received first two doses of hepatitis B vax in 1988. On 02/18/00, she received the third. Within the same month, she experienced an increase in her liver function tests and was then dxed with Epstein-Barr virus. Follow-up information indicated that approximately 20 days post vax, on 03/10, she developed nausea, vomiting, elevated liver enzymes, lymphadenopathy in her neck, and urticaria on her body. The pt was initially seen in the physician's office and later in the week, 03/10, she presented to the ER and was admitted to the hospital. Labs were conducted. The physician noted on her admission that there was a possibility that she had a sub-clinical hepatic reaction to the vax. At the time of hospitalization, the etiology was unclear. Gallbladder ultrasound, CT abdomen scan were all within nml limits. The biliary tree was not dilated. The gallbladder appears to be very small, however, contracted and contained small ill defined opacities which may represent biliary sludge of tiny gallbladder calculi. The spleen was mildly enlarged and show homogeneous attenuation. The pancreas, adrenal glands and kidneys are within nml limits. There is no evidence of free fluid in the pelvic cavity. The impression was top normal size liver, mild splenomegaly, small contracted gallbladder, probably secondary to cholecystitis. There are small faint opacities with the lumen of the gallbladder calculi. The remainder of the CT scan was unremarkable. According to the physician, this pt was febrile to 103.1 F in the past, but currently afebrile. Other vitals were unremarkable. Ear, nose and throat assessment showed slight icterus. Significant lymphadenopathy in the anterior cervical chains were noted in the neck exam. Heart, lungs, abdomen, and neurologic exam nml. Extremities had no edema but showed urticaria on face, neck, trunk and arms. The impression was elevated liver enzymes with lymphadenopathy and urticaria, the differential of this condition is long, however the physician believed the possibility of two concurrent conditions was likely. He reported mononucleosis with concurrent chemical dermatitis; subclinical hepatitis from clinical agent causing contact dermatitis or subclinical hepatitis from Hepatitis B vax, possible common bile duct obstruction, concurrent dermatitis. The plan was hydration and observation. The pt was discharged on 03/11. She was observed and 3rd set of liver enzymes was significantly improved but bilirubin was essentially unchanged. She feels well, is eating, somewhat nauseated, but not vomiting. She was discharged to bed rest and was restart Medrol Dosepak and follow up with physician on 03/13.