Sex: M
Vaccine: COVID19
Symptoms: Antibody test, SARS-CoV-2 antibody test, Vaccination site pain
Clinical narrative: This is a spontaneous report from a contactable consumer (patient) via a Pfizer-sponsored program A 62-year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), via an unspecified route of administration in Feb2021 (Batch/Lot number was not reported) as 2nd dose, single for COVID-19 immunisation.  The patient's medical history and concomitant medications were not reported. The patient also received first dose of BNT162B2 in Feb2021 for COVID-19 immunisation and experienced little pain at the point of the injection (first vaccine was not given properly). The patient received two doses of the Pfizer COVID vaccine in Feb2021 and he had some doubt about the second vaccine experience whether he got a full dose unlike the first. His first experience he got the needle, he felt the pinch, and got the vaccine hit his muscle inside, it was hard to describe for the patient, but it was an interior sensation. He mentioned that he didn't had any of those sensations with the second dose and also, had a little pain at the point of the injection of the first one. So, the second one, it was so minimal. He went inside for 15 minutes and soon as he was ready to get up and leave and he tried to go back to the vaccine administration station to find the team who administered the vaccine to him, but they were no longer there. So, he told their supervisor that there was something wrong with his 2nd dose.  He couldn't find a new 'run break' or something.  The patient further stated, "So anyways I hoped it was nothing and I kind of took that for granted that I got something if not maybe wasn't a full dose or whatever".  Then two weeks ago, the patient decided to make a doctor's appointment to get the 'Anti' SARS CoV-2, Spike Protein Antibody Test and his number came back with its right above, it's little bit above the number for the person to have one dose of the vaccine and it's about 70% lower than the lowest immune response, the lowest number of antibody a person would have received with the two doses. 8 weeks later, he got a  test to test for the RBG binding site of the spike protein. He took the test twice: 1st reading: 194.5 units per ml; 2nd reading: 194.1 units per ml. He said the test somehow confirmed that he did not get a normal antibody response with the 2nd dose. He said the level of antibodies he had were just above the mean for a person who received just the 1st dose. He said the lowest antibody count for persons who have received both doses were 795 to 800 units per ml, and his falls below this. He also mentioned that only people who have chronic lymphocytic leukemia were the only ones who had less than 795-800 units per ml. With this, he wants to know if there is any way he can get a repeat of his 2nd dose, or if he can get a 3rd dose somewhere.  The patient mentioned that there were things about the second dose administration that made him think that he was under dosed. His antibody titer levels came in exactly just slightly above the number that is for person who had only one dose. Immunity is going to diminish as it is not that great, it is about a tenth as high on average as the immunity that should have come from the second shot. It should have been much more immunity with the second shot, and it doesn't look like he had a second shot. It doesn't look like he has got much serum. And there about he had looked at the studies of the distribution and not trying to make a claim about the immunity. The patient further stated, "What I am making the strong claim about the correlation between the number of antibody that they took up in this test and rather one got one or two doses and there is not a single person in the five studies, in the part of gigantic studies of 500 person, there is not a single person who's received two full doses who has an antibody title level that is as low as mine except for somebody with, there were two people with CL low that is the chronic Leukemia low, leukemia who has zero antibodies. So I look at this all and I believe that I somehow got a very substandard second dose and I spoke to number of doctors and I hope my doctors and doctors that are friend of mine that teach at different medical school, they all agree with the analysis but nobody knows how to go about getting an authorization for the third dose".  The patient mentioned that he tried his doctors and they don't have any idea because it's not something that's prescribed, it's the matter of CDC rules and he have called and written to the department of public health in agony and he got no information back as to how he can proceed.  The patient stated he must have had the substandard amount of the serum because he is not immunocompromised in anyway. He checked that out, had his doctor double checked, look at the CDC and he is not immunocompromised, so it is not even that he is at the low end of spectrum of those who had received the second dose. The patient was wondering if Pfizer have any recommendations as to how he should proceed. He had no doubt unfortunately that he had substandard, he must have had the substandard amount of the serum because he was not immunocompromised in anyway.  The patient mentioned that he had 100's of point below at every scale that was different. Outcome of the event was unknown.   Information about the lot/batch number has been requested.