Sex: M
Vaccine: VARZOS
Symptoms: Herpes zoster, Loss of personal independence in daily activities, Pain, Post herpetic neuralgia, Skin ulcer
Clinical narrative: very large sores over a large area from the belly bottom to the backbone on the left side / about 10 inches high from my waist up; pain; can't get dressed or drive; got  both Shingrix vaccines "like 3 years ago." / Shingles on June 2020/ suspected Vaccination failure; PHN that has last for 9 months; "really bad" case of Shingles; This case was reported by a consumer via call center representative and described the occurrence of suspected vaccination failure in a 76-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Shingles vaccine (received 10 years before the date of reporting).   On an unknown date, the patient received the 1st dose of Shingrix and the 2nd dose of Shingrix. In June 2020, more than 2 years after receiving Shingrix and Shingrix, the patient experienced vaccination failure (serious criteria GSK medically significant), shingles and post herpetic neuralgia. On an unknown date, the patient experienced skin ulcer, pain and activities of daily living impaired. The patient was treated with opioids {nos} (Opioids). On an unknown date, the outcome of the vaccination failure, skin ulcer, pain and activities of daily living impaired were unknown and the outcome of the shingles was recovered/resolved and the outcome of the post herpetic neuralgia was not recovered/not resolved.   It was unknown if the reporter considered the vaccination failure, shingles and post herpetic neuralgia to be related to Shingrix and Shingrix. It was unknown if the reporter considered the skin ulcer, pain and activities of daily living impaired to be related to Shingrix.  Additional details were reported as follows: This case was reported by patient himself. The age at vaccination was not reported. The patient received both Shingrix vaccines like 3 years before the date of reporting. The patient received the first dose in the right arm and the second dose in the left arm. The patient did not provide the dates when he got vaccinated but states that he got the second dose around 2 months plus the first dose, in the proper spam of time. The patient experienced a really bad case of Shingles on June 2020 that lasted about a month. The patient also reports having very large sores over a large area from the belly bottom to the backbone on the left side, and about 10 inches high from his waist up.  The patient stated that he has PHN that has last for 9 months. The patient was taking opioids for pain, but they don't really help. He could not get dressed or drive. The patient states he was receiving signals to the nerves and a Spinal peripheral stimulator for the PHN. Patient states that PHN was worse than Shingles. Patient states he has not recovered from PHN. This case was considered to be a suspected vaccination failure case, as the details regarding laboratory confirmation for shingles was unknown. All information was not available. Dates of vaccines and lots and expiration dates were not available during the call but reporter states that this information could be obtained. The reporter consented to follow up.