Age: 1.0
Sex: M
Vaccine: MMR
Symptoms: Aphasia, Blood test abnormal, Body temperature increased, Brain injury, Eye colour change
Clinical narrative: the HCP conducted "blood tests against the new born blood tests and found that it was quite different"; the consumer was "very lethargic"; "lost his speech until seven years old"; MRI done and the results showed "some brain damage"; the consumers "eye color changed from bright blue to gray"; temperature of 104 F for three days; had the exact side effects that are listed at all intervals of two, four, and six weeks; This spontaneous report was received from the patient's mother, referring to a 1-year-old male patient. It was reported that the patient had drug reaction or allergies to Augmentin. The patient did not have other pertinent medical history or concomitant medications.  On 28-NOV-2005, the patient was vaccinated with his first dose of measles, mumps, and rubella (wistar ra 27-3) virus vaccine, live (human serum albumin (HSA)) (M-M-R II) at a dose of 0.5 milliliter (mL), by injection route in the left thigh as prophylaxis recommended by the doctor (exact route of administration and vaccination scheme frequency were not reported; lot number 0378R has been verified to be a valid lot number for measles, mumps, and rubella (wistar ra 27-3) virus vaccine, live (M-M-R II), expiration date reported and but upon internal validation established as 24-MAR-2007).  On an unknown date in 2005, the patient had the exact side effects that are listed at all intervals of two, four, and six weeks (vaccination complication) and ending with a temperature of 104 degrees Fahrenheit (F) for three days (pyrexia). The patient was treated with Tylenol and Ibuprofen.  On unknown date in February 2006 (reported as "at 18 months of age"), the patient eye color changed from bright blue to gray (eye colour change).  On an unknown date in 2007 (reported as "at three years old"), the patient had an magnetic resonance imaging (MRI) done and the results showed "some brain damage" (brain injury).   On an unknown date, the healthcare professional (HCP) conducted "blood tests against the new born blood tests and found that it was quite different" (blood test abnormal). After the initial event the reporter stated that the patient was "very lethargic" (lethargy) and "lost his speech until seven years old" (aphasia) only gaining it back after extensive speech therapy.  It was reported that the patient sought medical attention.   Under the recommendation from the HCP, the patient did not get the second shot. The outcome of the events brain injury, eye colour change, lethargy and blood test abnormal were not reported. The outcome of the events vaccination complication, pyrexia and aphasia was reported as resolved. The causal relationship between the event vaccination complication was considered to be related to Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (HSA) (M-M-R II). The causal relationship between the event brain injury, eye colour change, lethargy, blood test abnormal, pyrexia and aphasia and Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (HSA) (M-M-R II).   Upon internal review, the event brain injury was considered to be medically significant.