Sex: F
Vaccine: COVID19
Symptoms: Dyspnoea, Emotional distress, Loss of personal independence in daily activities, Malaise, Pain
Clinical narrative: Difficulty breathing; Acute cardiac arrest; not able to eat or drink on her own/ her daughter started spoon feeding/ Her daughter was giving her assistance in mobility for movement inside the house/ not able to follow verbal instructions given by daughter; Stomach hunger pain; Thirst; physical anguish; physical pain; physical deterioration; mental confusion; mental stress/mental suffering/mental deterioration/mental anguish; deliria; This spontaneous case was reported by an attorney and describes the occurrence of CARDIAC ARREST (Acute cardiac arrest) and DELIRIUM (deliria) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 07-Mar-2021 at 2:00 PM, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 08-Mar-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (not able to eat or drink on her own/ her daughter started spoon feeding/ Her daughter was giving her assistance in mobility for movement inside the house/ not able to follow verbal instructions given by daughter). In March 2021, the patient experienced DELIRIUM (deliria) (seriousness criterion medically significant), ABDOMINAL PAIN UPPER (Stomach hunger pain), THIRST (Thirst), ANXIETY (physical anguish), PAIN (physical pain), MALAISE (physical deterioration), CONFUSIONAL STATE (mental confusion) and EMOTIONAL DISTRESS (mental stress/mental suffering/mental deterioration/mental anguish). On 18-Mar-2021, the patient experienced CARDIAC ARREST (Acute cardiac arrest) (seriousness criteria death and medically significant) and DYSPNOEA (Difficulty breathing). The patient died on 18-Mar-2021. The reported cause of death was acute cardiac arrest. It is unknown if an autopsy was performed. At the time of death, DELIRIUM (deliria), DYSPNOEA (Difficulty breathing), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (not able to eat or drink on her own/ her daughter started spoon feeding/ Her daughter was giving her assistance in mobility for movement inside the house/ not able to follow verbal instructions given by daughter), ABDOMINAL PAIN UPPER (Stomach hunger pain), THIRST (Thirst), ANXIETY (physical anguish), PAIN (physical pain), MALAISE (physical deterioration), CONFUSIONAL STATE (mental confusion) and EMOTIONAL DISTRESS (mental stress/mental suffering/mental deterioration/mental anguish) outcome was unknown.            It was reported that between 1-Jan-2020 and 6-Mar-2021, the patient was enjoying her life as a healthy individual free from physical illness of any kind, her heart was healthy along with her healthy physical body. No concomitant medications were reported. On 8-Mar-2021, the patient stayed in bed until late afternoon, and she was not able to eat or drink on her own. From that day her daughter started spoon feeding. Her daughter was giving her assistance in mobility for movement inside the house along with additional assistance in dressing and undressing. From 8-Mar-2021, the patient was not able to follow verbal instructions given by daughter. On 18-Mar-2021, after 12 midnight, the patient began grasping for breath and had difficulty in breathing. The patient was taken to the emergency room via ambulance but passed away while being transported to the hospital at approximately around 2:45 pm. It was reported that acute cardiac arrest caused wrongful death of the patient. No treatment medications were reported.  Company Comment: This is a spontaneous case concerning a female patient with no reported medical history, who experienced the serious (due to medically significant and Fatal) unexpected event of Cardiac arrest and the serious (due to medically significant) unexpected event of Delirium, among other non-serious events. The event Cardiac arrest occurred approximately 11 days after a dose of mRNA-1273 vaccine (dose number was not reported) and the event Delirium, and other non-serious events occurred on an unknown date after vaccination. As reported, on 8-Mar-2021, the following day after vaccination, the patient stayed in bed until late afternoon, and she was not able to eat or drink on her own. From that day her daughter started spoon feeding, and giving her assistance in mobility inside the house along with additional assistance in dressing and undressing. In addition, the patient was not able to follow verbal instructions given by daughter. On 18-Mar-2021, after 12 midnight, the patient began grasping for breath and had difficulty in breathing. The patient was taken to the emergency room via ambulance but passed away while being transported to the hospital at approximately around 2:45 pm. It was reported that acute cardiac arrest caused wrongful death of the patient. Circumstances leading to death, supportive diagnostic procedures, treatment, and whether an autopsy was performed or not, were not provided. The outcome of the event was reported as fatal. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Reported Cause(s) of Death: Acute cardiac arrest