Sex: F
Vaccine: TYP
Symptoms: Anaphylactic reaction, Asthenia, Diarrhoea, Dyspnoea, Ear swelling
Clinical narrative: SHE HAD NO ENERGY; DID NOT FEEL WELL; SLIGHT HEADACHE; LOOSE STOOLS; ANAPHYLACTIC REACTION / SHORTNESS OF BREATH/ SWOLLEN TONGUE, THROAT AND BODY AND SHE WAS RED ALL OVER / SHE WAS DISCOLORED/ INCREASED HEART RATE FROM 50 TO HIGH 70; KNEES WERE LOCKED WHEN SHE TRIED TO GO DOWN THE STAIRS; This spontaneous case report (PVX2019-2793) was received from a consumer on 12-Nov-2019. It described a female consumer who "had anaphylactic reaction (including symptoms shortness of breath, swollen tongue, throat and body and she was red all over, she was discoloured)" (PT: Anaphylactic reaction), "she had no energy" (PT: Asthenia), "did not feel well" (PT: Malaise),  "slight headache" (PT: Headache), "loose stools " (PT: Diarrhoea), and "her knee were locked when she tried to go down the stairs" (PT: Joint lock) while being on  Vivotif for an unknown indication.  Case report: The consumer took first dose of Vivotif on 28-Oct-2019. On next day on 29-Oct-2019, she was unable to get out of bed, had red spots on her face and also felt terrible and her knees were locked when she tried to go down the stairs. On 30-Oct-2019, she had anaphylactic reaction with associated symptoms of shortness of breath, swollen tongue, throat and body, also she became red all over the body, and she was discoloured, for which she took Benadryl (diphenhydramine) in the night as a treatment. On the same day, she went to her Primary Care Clinic where they took her Vivotif back. At the time of reporting, she had elevated heart rate from 50s to 70s, had no energy, slight headache, loose motion and did not feel well.  Her concomitant medications included regular blood pressure medication.  Action taken with Vivotif with respect to reported events was vaccine discontinued.  The clinical outcome of event "her knee were locked when she tried to go down the stairs" was unknown, while the outcome of all of the other events was not resolved.  Company's Comment: In this case it was reported that a female consumer had anaphylactic reaction with associated symptoms of shortness of breath, swollen tongue, throat and body, also she became red all over the body following administration of Vivotif. Also, "she had no energy", "did not feel well", had "slight headache", "loose stools ", and "her knees were locked when she tried to go down the stairs". The events have been reported with reasonable time relation to time of vaccine. Also, the casual role of vaccine cannot be ruled out. Hence, the causality has been assessed as possible for all the events.; Sender's Comments: Company's Comment: In this case it was reported that a female consumer had anaphylactic reaction with associated symptoms of shortness of breath, swollen tongue, throat and body, also she became red all over the body following administration of Vivotif. Also, "she had no energy", "did not feel well", had "slight headache", "loose stools ", and "her knees were locked when she tried to go down the stairs". The events have been reported with reasonable time relation to time of vaccine. Also, the casual role of vaccine cannot be ruled out. Hence, the causality has been assessed as possible for all the events.