Age: 29.0
Sex: F
Vaccine: COVID19
Symptoms: Muscle spasms, Premature separation of placenta
Clinical narrative: Which continued throughout my pregnancy and I then had a placental abruption preterm; I received vaccine during my first trimester of 2nd pregnancy. I had awful cramping that started after my 2nd dose.; This is a spontaneous report received from a contactable reporter(s) (Nurse). The reporter is the patient.  A 29-year-old female patient (pregnant) received BNT162b2 (BNT162B2), on 23Sep2021 as dose 2, single (Lot number: FF2687) at the age of 29 years, in left arm for covid-19 immunisation. The patient's relevant medical history was not reported. The patient was 3 weeks pregnant at the event onset. Concomitant medication(s) included: PRENATAL VITAMINS [ASCORBIC ACID;BETACAROTENE;CALCIUM SULFATE;COLECALCIFEROL;CYANOCOBALAMIN;FERROUS FUMARATE;FOLIC ACID;NICOTINAMIDE;PYRIDOXINE HYDROCHLORIDE;RETINOL ACETATE;RIBOFLAVIN;THIAMINE MONONITRATE;TOCOPHERYL ACETATE;ZINC OXIDE]. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Batch/Lot No: FC3182, Location of injection: Leg Left), administration date: 26Aug2021, when the patient was 29-year-old, for COVID-19 immunization. The following information was reported: MUSCLE SPASMS (life threatening) with onset 01Oct2021, outcome "recovered with sequelae", described as "I received vaccine during my first trimester of 2nd pregnancy. I had awful cramping that started after my 2nd dose."; PREMATURE SEPARATION OF PLACENTA (medically significant, life threatening) with onset 01Oct2021, outcome "recovered with sequelae", described as "Which continued throughout my pregnancy and I then had a placental abruption preterm". The events "which continued throughout my pregnancy and i then had a placental abruption preterm" and "i received vaccine during my first trimester of 2nd pregnancy. i had awful cramping that started after my 2nd dose." required physician office visit and emergency room visit. Therapeutic measures were taken as a result of premature separation of placenta, muscle spasms.  Clinical course: She had no issues with her pregnancy or delivery for her first child. Emergent C Section did for patient. She received vaccine during my first trimester of 2nd pregnancy. I had awful cramping that started after my 2nd dose. Which continued throughout my pregnancy, and I then had a placental abruption preterm. The AE resulted in other healthcare professional office/clinic visit, Emergency room/department or urgent care, life threatening illness (immediate risk of death from the event).  Follow-up attempts are completed. No further information is expected.; Sender's Comments: Based on the available information in the case, an association between the reported events MUSCLE SPASMS & PREMATURE SEPARATION OF PLACENTA  and The suspected drug cannot be ruled out.  The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.