Age: 41.0
Sex: F
Vaccine: COVID19, COVID19, COVID19, COVID19
Symptoms: SARS-CoV-2 test negative, Sepsis, Splenomegaly, Surgery, Transfusion
Clinical narrative: Brief Medical Summary (January 2022 - June 2022):  Medical Diagnosis?: Epstein Barr Virus, Cholecystitis, Vitamin A Toxicity, Sepsis, Gallstones, Biliary Leak, Pleural Effusion, Hepatitis, Jaundice, Splenomegaly, Anemia, Unintended Weight Loss, Retroperitoneal Abscess, Pelvic Abscess.  I had 7 surgical procedures and 4 hospital admissions.  I lost a total of 25 lbs and had dropped to 87 lbs.  I?m currently only 42 years old, a gluten-free vegan, and had previously been in excellent health.  My Full Story:  In late January 2022, I was on a trip. I spiked a high fever and had violent chills, abdominal pain and headaches. Urgent care tested me for Covid and the flu, and I was negative. The doctor advised me to get lab work and have my gallbladder checked (I knew I had gallstones, but they had never bothered me).  I waited a couple more days until my flight back and flew home, not feeling well at all. The next day, my husband brought me to the ER. It turned out my gallbladder was very inflamed/infected (cholecystitis) and stones were blocking my bile duct. I had emergency gallbladder removal surgery that night. I was discharged the next day. However, after only a night at home, I spiked a fever, had gained 10 lbs since the surgery and returned to the ER. Then, after multiple tests, it was determined that I had a biliary leak and had an ERCP, followed by a biliary stent placement. Then after two more days, my liver numbers were very elevated, so a couple liver biopsies were performed on my inflamed liver (diagnosed with Hepatitis & Jaundice). I bled a lot during that procedure. My spleen was also inflamed (Splenomegaly).  On February 14th, the biopsy results confirmed that I had Epstein Barr Virus and Vitamin A toxicity (likely from a supplement I was taking). I was also very anemic from the blood loss and I needed several blood transfusions. I was moved to ICU.  Also at this time, doctors were concerned I might need a liver transplant. I was extremely ill and lethargic during this time. My family, friends are I were very concerned and didn?t know if I would make it.   After a few more days, my liver numbers slowly stabilized and I was no longer in immediate danger of needing a liver transplant. I was discharged on February 24th.   But this wasn?t over? on March 9th, I spiked a fever and had very low blood pressure so I went back to the ER. I was admitted again, diagnosed with Sepsis, pleural effusion and learned that I had an infected abscess. A JP drain was put in to my right retroperitoneal cavity to help drain fluid. On March 16th, a PICC line was put in and I was prescribed IV antibiotic infusions every 6 hours. I was discharged on March 21st.   In early April, I spiked another fever and had pain at the drain site. I went back to the ER and was admitted for the 4th time. The drain tube was replaced a few days later and the fluid was cultured again. It was determined that I also had a fungal infection that required more IV meds. I had surgeries on April 19th and again on the 21st to clean out some of the abscess fluid in the right retroperitoneal cavity and my drain was switched to a penrose drain. I was discharged on Apr 22nd. I was so frail and weak?I could barely walk and couldn?t even climb stairs.   I had multiple CT scans and learned that the abscess fluid wasn?t really going away in the left retroperitoneal cavity, nor the pelvis. I then decided to get a 2nd opinion.   On May 17th, I had a procedure at another hospital to put in two additional drains (JP drains in the left retroperitoneal cavity and pelvis). I had the drains in for several weeks, and the PICC line in for 100 days, but as of late June, I am finally drain PICC line, and antibiotic infusion free!  I am now back to 107 lbs and my labs have finally normalized after 6 months!  I never had mono and I'm not sure what triggered such an intense EBV response in my body.