Age: 12.0
Sex: F
Vaccine: HPV4
Symptoms: Syncope
Clinical narrative: POTS; Complex Regional Pain Syndrome (CRPS); Sustained Serious Autoimmune injuries; Gastrointestinal issues/ food intolerance; Mast Cell Activation Syndrome ("MCAS"); Information was received from a lawyer, regarding a case in litigation and refers to a 12-years-old female patient (pt). The pt's concurrent conditions, concomitant medications and medical history  were not provided.  On an unknown date (at the age of 12-years-old), the pt was vaccinated with the first and only dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) (exact dose, route of administration, anatomical location, lot # and expiration date were not provided) administered for prophylaxis (also reported as "touted as a safe and effective vaccine for preventing cervical cancer"), with the pt's physician recommendation and the pt's mother consented.  On unspecified dates, the pt experienced serious autoimmune and neurological injuries as a result of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL). On other unknown dates, within a few weeks after receiving the vaccine, the patient developed stomach pains, diarrhea, and body pains. As the months progressed, so did pt's injuries. She was seen by multiple physicians and specialists for her complaints which included: extreme body pain to the point where she could no longer walk, insomnia, nausea, fatigue, brain fog, erratic heartbeats, food intolerances, gastrointestinal issues, headaches, numbness in her arms and legs, neck pain, legs turning purple after prolonged standing, light and sound sensitivity, and syncope. As a result of her symptoms, the pt has been unable to engage in activities that a normal young person would enjoy. Prior to quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL), she was an active teenager who enjoyed playing sports and participating in extracurricular activities at school. Since receiving the vaccine, the patient has had difficulty attending school and had to enroll in community college instead of a full-time university. She has also had to apply for disability.  Based upon her chronic and severe post-quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, pt has been diagnosed with various medical conditions, including but not limited to, Postural orthostatic tachycardia syndrome (POTS), Complex Regional Pain Syndrome (CRPS), joint pain, chronic migraine, neck pain, orthostatic intolerance, decreased level of consciousness, and Mast Cell Activation Syndrome ("MCAS"). It was also confirmed that the pt suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of the events was considered to be not recovered.  The reporter considered all the aforementioned events to be related to quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL).   Upon internal review, the events of mast cell activation syndrome and autoimmune disorder were determined to be medically significant. The reporter considered all events to be disabling.