Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Atrial fibrillation, Catheterisation cardiac, Computerised tomogram, Echocardiogram, Electrocardiogram
Clinical narrative: Started with arrhythmias and then; the arrhythmia became defined; it was atrial fibrillation; I developed another arrhythmia which is Premature Ventricular Contractions PVC; neurological issues; I am only partially functional as far as physically; I am exhausted; This is a spontaneous report received from a Nurse.  A 75-year-old female patient received BNT162b2 (BNT162B2), as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose 1, lot number unknown), for COVID-19 immunization; Bnt162b2 (Dose 2, lot number unknown), for COVID-19 immunization. The following information was reported: ATRIAL FIBRILLATION (hospitalization) with onset 2021, outcome "unknown", described as "Started with arrhythmias and then; the arrhythmia became defined; it was atrial fibrillation"; VENTRICULAR EXTRASYSTOLES (non-serious), outcome "unknown", described as "I developed another arrhythmia which is Premature Ventricular Contractions PVC"; NERVOUS SYSTEM DISORDER (non-serious), outcome "unknown", described as "neurological issues"; MALAISE (non-serious), outcome "unknown", described as "I am only partially functional as far as physically"; FATIGUE (non-serious), outcome "unknown", described as "I am exhausted". The events "started with arrhythmias and then; the arrhythmia became defined; it was atrial fibrillation" required emergency room visit. The patient underwent the following laboratory tests and procedures: Catheterisation cardiac: Unknown Results; Computerised tomogram: Unknown Results; Echocardiogram: Unknown Results; Electrocardiogram: Unknown Results. Therapeutic measures were taken as a result of atrial fibrillation. Clinical courses: The patient has had all her vaccines. She has the initial two with a Pfizer and booster with the Pfizer and not long after she got her booster (Pfizer COVID-19 Vaccine). The patient started with arrhythmias and then, the arrhythmia became defined, it was atrial fibrillation. She was hospitalized several times (also reported as 4 times or 5 times). They tried a variety of ways of converting it back in the normal finest rhythm. After two hospitalizations could not get it controlled and so the patient round up getting a pacemaker and defibrillator and then, she developed another arrhythmia which is Premature Ventricular Contractions PVC and after that she developed neurological issues and her life has dissolved into an absolute nightmare and she has had multiple hospitalizations. The patient believes that it has to do with the vaccines that she had and she will tell that the day she was admitted the first time with atrial fib and they did a chemical drip and they did. They tried to cardiovert her, electrically that, nothing worked. She had Diltiazem (Further manufacturer name was not available), but the same day the same time going into the emergency room at the same hospital. She has lived with atrial fib for the past three years and it had been a nightmare. her life has dissolved into a nightmare. The patient need oxygen 24/7. She has a pacemaker, a defibrillator. She was only partially functional as far as physically, she was exhausted and then she started to get angry. So, that is why she was calling now. The patient is 78 years old now, it started 3 years ago. She was not quite 75 and she was in good health and working (reporter was not sure). The patient had tons of lab work. Tons of EKG, Echo cardiogram, CT scans, a heart catheterization, a left heart catheterization, a right heart catheterization. She spent the night in the ICU with Diltiazem drip in the ICU and in the coronary care, intermediate unit. She has had plenty of medical care and it just keep getting worse. She has had two hospitalizations at #. The reporter believe it is related to the COVID vaccines that she had.   The information on the batch/lot number for BNT162b2 will be requested and submitted if and when received.; Sender's Comments: Although it is difficult to establish temporal association between the reported event ATRIAL FIBRILLATION and suspect drug based on the limited information provided in the case, the causal association between the Reported event and the suspect drug cannot be excluded  as there is no concrete evidence available to eliminate the causal association The impact of this report on the benefit/risk profile of the Pfizer drug is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees, and Investigators, as appropriate.