Age: 53.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Arthralgia, Deep vein thrombosis, Gait disturbance, Mobility decreased, Myalgia
Clinical narrative: Blood clots in right leg below knee; he passed out from pain; pain in his right knee; he couldn't bend his knee at all; knee was swollen; couldn't walk/limping around; his knee more stiff; This is a spontaneous report from a contactable consumer (patient). A 53-year-old male patient received the first dose of BNT162B2 (Pfizer-BioNTech COVID-19 vaccine, lot number: EN6206), via an unspecified route of administration, administered in the right arm on 21Mar2021 at 10:00 as a single dose for COVID-19 immunization.  Medical history included ongoing Factor V Leiden heterozygous, allergies to mushrooms from an unknown date and unknown if ongoing and a torn meniscus in his right knee and he had surgery 3 to 4 years ago. The patient's concomitant medications were not reported. The patient previously took Cephalexin and Percocet and experienced allergies. The patient did not have COVID prior to vaccination and has not been tested post vaccination. On 22Mar2021 at night around 2:30AM, the patient woke up and started walking to the bathroom and he passed out from pain. He had pain in his right knee. He thought he had torn his knee again. He had surgery 3 or 4 years ago for a torn meniscus in his right knee and he thought he had torn his meniscus again. He passed out, his wife found him and he went back to bed. In the morning, his knee was still very very sore, he couldn't bend his knee at all. He took an Advil between 6:30AM and 8:00AM. He hadn't taken any medications prior to the COVID-19 vaccine. His knee was swollen but the pain was manageable. He couldn't walk, he was on crutches for about 24 hours then the swelling started coming down and he put a brace on his knee. He could then walk without the crutches but it was still painful. The next day he had pain in the back of his knee. He thought the pain was caused because he had put the brace on and had been using the crutches. Like he had made his knee more stiff from not using it. He was limping around and the pain was bearable. At that point, the pain was maybe a 4 on a scale of 1-10 where his pain had been a 9 on a scale of 1-10. He took another Advil and he realized the pain in the back of his knee wasn't going away. He went to see his family doctor and his doctor was able to get him in that same day for an ultrasound. The ultrasound showed 2 blood clots behind his right knee. The patient had blood clots in right leg below knee. The week of the report, he got an appointment with a hematologist. The hematologist reviewed his case and the doctor isn't 100% sure the blood clots were from the Pfizer COVID-19 vaccine but the doctor isn't ruling it out either because it happened within 24 hours of receiving his first COVID-19 dose. He hadn't done anything strenuous before getting the COVID-19 vaccine, nothing that he thinks would have caused the blood clots. He would like to add, what he thinks is relevant, is that he is positive for Factor V. He reports he has one copy and Factor V only impacts about 3% of the population. The hematologist thought that he might be prone to developing blood clots. The hematologist reports that he has had patients who have had the COVID-19 virus who have developed blood clots. Maybe it's possible that the COVID-19 antibodies were trying to build up his immune system to COVID-19 and it created something similar to having the COVID-19 virus. If he is predisposed to blood clots then the COVID-19 vaccine may have precipitated the blood clots. His second COVID-19 vaccine is scheduled for Sunday, 11Apr2021. He had talked to both his family doctor and his hematologist and they both thought he should be ok in getting the second COVID-19 vaccine. He was prescribed blood thinners. If the second COVID-19 vaccine caused more blood clots the blood thinners would help him. He was asking if there is any additional information or guidance on receiving the second COVID-19 vaccine after his reaction. The pharmacist told him that the COVID-19 vaccine trials were all done in the left arm. He received his vaccine in his right arm and his right knee was affected. If he gets the second COVID-19 vaccine he's getting it in his left arm. He was prescribed Eliquis 5mg take one tablet twice daily. The outcome of the event blood clots in right leg below knee was recovering while the outcome of the other events was unknown.