chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 4.0
Sex: F
Vaccine: DTAP, HEP, IPV
Symptoms: Abdominal pain upper, Injection site mass, Pyrexia, Vomiting
Clinical narrative: On 07/07/2001 the patient awoke complaining of a stomach ache, vomited one time, and had an oral temperature of 105F. The patient was treated with Tylenol and was able to tolerate liquids and small amounts of solid food. The fever never dropped below 100F. The patient did go outside to play at 6:30pm and experienced vomiting again. The patient slept through the night with no further vomiting. On 07/08/2001 the patient had developed a sore lump at the injection site. Treatment with Tylenol continued. A physician visit was not required.
Age: 4.0
Sex: M
Vaccine: DTAP, HEP, IPV, MMR
Symptoms: Erythema, Oedema, Pain, Pyrexia, Shoulder pain
Clinical narrative: On 07/14/2001 the patient developed erythema. The patient awoke on 07/15/2001 with edema and severe pain in the right upper arm and shoulder. The patient was seen in the ER and treated with Ceclor. The patient had a low grade fever 07/15/2001 through 07/17/2001.
Age: 1.08
Sex: F
Vaccine: DTAP, HBHEPB, IPV, MMR, VARCEL
Symptoms: Urticaria
Clinical narrative: Within 5 minutes post-vax, the patient developed 2 hives on her upper right arm. One 15mm hive measured adjacent to the Varicella vaccine site and one 10mm hive measured adjacent to the MMR vaccine site. The patient was treated with Benadryl and advised to report this to her pediatrician.
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR
Symptoms: Arthralgia, Asthenia, Dyspnoea, Joint stiffness, Pyrexia
Clinical narrative: Post-vax the patient developed joint pain on 06/25/2001. The patient was seen in the ER and discharged home. On 06/27/2001 the patient was febrile, vomiting, had joint stiffness with pain, weakness and difficulty breathing. The patient is returning to the ER today.
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR
Symptoms: Vomiting
Clinical narrative: Post-vax the patient developed joint pain on 06/25/2001. The patient was seen in the ER and discharged home. On 06/27/2001 the patient was febrile, vomiting, had joint stiffness with pain, weakness and difficulty breathing. The patient is returning to the ER today.
Age: 13.0
Sex: F
Vaccine: JEV
Symptoms: Dysphagia, Dyspnoea, Injection site pain, Injection site warmth, Pharyngeal oedema
Clinical narrative: The patient reported approximately 36 hours post-vax tightness in her throat, difficulty breathing and swallowing. The patient denied fever, hives, rash, dizziness, nausea, or sensory changes. The patient went to an urgent care center where she was found to be alert and oriented, right upper arm area with warmth, tenderness at the injection site, tonsils mildly enlarged with erythema, nose clear, neck supple, no adenopathy, and no cardiac or respiratory abnormalities. Patients gait was normal, BP 120/72, HR 64, R 16, T 99.3. The patient was treated with Prednisone and Benadryl.
Age: 13.0
Sex: F
Vaccine: JEV
Symptoms: Pyrexia, Throat tightness
Clinical narrative: The patient reported approximately 36 hours post-vax tightness in her throat, difficulty breathing and swallowing. The patient denied fever, hives, rash, dizziness, nausea, or sensory changes. The patient went to an urgent care center where she was found to be alert and oriented, right upper arm area with warmth, tenderness at the injection site, tonsils mildly enlarged with erythema, nose clear, neck supple, no adenopathy, and no cardiac or respiratory abnormalities. Patients gait was normal, BP 120/72, HR 64, R 16, T 99.3. The patient was treated with Prednisone and Benadryl.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site hypersensitivity, Injection site induration, Injection site warmth, Lymphadenopathy
Clinical narrative: The patient experienced redness, warmth, induration, and itchiness in a 7-8 cm diameter area at the injection site with associated axillary adenopathy.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Pruritus
Clinical narrative: The patient experienced redness, warmth, induration, and itchiness in a 7-8 cm diameter area at the injection site with associated axillary adenopathy.
Age: 86.0
Sex: F
Vaccine: PPV
Symptoms: Injection site erythema, Injection site pain
Clinical narrative: Post-vax the patient experienced localized erythema and tenderson.
Age: 5.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site erythema, Rash papular, Urticaria
Clinical narrative: The patient developed papular urticaria approximately 24 hours post-vax. This was a waxing and waning generalized rash. No respiratory, upper airway, or edema complications. The patient had an erythematous localized reaction at the MMR site. Patient was seen in the clinic and treated with Benadryl.
Age: 13.0
Sex: F
Vaccine: HEP
Symptoms: Syncope
Clinical narrative: The patient experienced a syncopal episode approximately 10 minutes post-vax. The patient hit her head on the door and wall, and about 5 seconds later the patient came to and stated she's fine. The patient was reevaluated with a normal ultrasound and neurological exam.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anorexia, Antinuclear antibody, Bleeding time prolonged, Blood lactate dehydrogenase increased, Brain oedema
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Disseminated intravascular coagulation, Haemolytic anaemia, Hypoxia, Laboratory test abnormal, Leukocytosis
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Pyrexia, Somnolence, Stupor, Subarachnoid haemorrhage, Thrombocythaemia
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Urinary tract infection, White blood cell disorder
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Brain oedema, Coombs positive haemolytic anaemia, Disseminated intravascular coagulation
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Enzyme abnormality, Haemolysis, Hypoxia, Leukocytosis, Pyrexia
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Somnolence, Stupor, Subarachnoid haemorrhage, Thrombocythaemia
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Blood lactate dehydrogenase increased, Brain oedema, Disseminated intravascular coagulation
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Haemolysis, Haemolytic anaemia, Leukocytosis, Pyrexia, Somnolence
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Stupor, Subarachnoid haemorrhage, Thrombocytopenia, Urinary tract infection, Urine analysis abnormal
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Brain oedema, Disseminated intravascular coagulation, Haemolysis
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Leukocytosis, Pyrexia, Somnolence, Stupor, Subarachnoid haemorrhage
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Urinary tract infection
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.3
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Irritability, Otitis media
Clinical narrative: Four days after the vaccinations given at 4 months of age, the pt presented with a low-grade fever, lethargy and decreased oral intake. The results of a urine leukocyte esterase test were positive. She was treated with Rocephin, 250mg IM, Bactrim, 3/4 tsp po every 12 hours and acetaminophen for a possible UTI. The results of the urine culture were negative. Three days later, the pt was admitted to the hospital with severe anemia. At the time of admission, the pt was unresponsive, ventilator dependent and showed evidence of disseminated intravascular coagulation. A warm auto antibody (panagglutinin), optimally reactive at 37C and without demonstrable specificity, was identified in both the serum and the red cell eluate. She was treated with 2 units of RBC's, 1 unit of platelets, 2 units of cryoprecipitate and 2 units of fresh frozen plasma. She was also treated with IV immune globulin, ampicillin 700mg IV X 1 dose then 350mg IV every 12 hours X 2-4 doses and Solu-Medrol 350mg IV every 6 hours X 8 doses after a loading dose. Severe hemolysis continued and the infant died 41 hours after admission. The autopsy demonstrated cerebral edema and diffuse subarachnoid hemorrhage but was otherwise non contributory. The author felt that, after excluding other causes, the development of warm AIHA in this pt suggests a causal relationship to the 2nd diphtheria toxoid (+) Haemophilus B conjugate vaccine + pertussis vaccine (+) tetanus toxoid (Tetramune) vaccination. F/U, the serious criteria of life-threatening has been removed. This is a corrected report, as amended.
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anorexia, Antinuclear antibody, Bleeding time prolonged, Blood lactate dehydrogenase increased, Brain oedema
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Disseminated intravascular coagulation, Haemolytic anaemia, Hypoxia, Laboratory test abnormal, Leukocytosis
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Pyrexia, Somnolence, Stupor, Subarachnoid haemorrhage, Thrombocythaemia
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Urinary tract infection, White blood cell disorder
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Brain oedema, Coombs positive haemolytic anaemia, Disseminated intravascular coagulation
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Enzyme abnormality, Haemolysis, Hypoxia, Leukocytosis, Pyrexia
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Somnolence, Stupor, Subarachnoid haemorrhage, Thrombocythaemia
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Blood lactate dehydrogenase increased, Brain oedema, Disseminated intravascular coagulation
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Haemolysis, Haemolytic anaemia, Leukocytosis, Pyrexia, Somnolence
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Stupor, Subarachnoid haemorrhage, Thrombocytopenia, Urinary tract infection, Urine analysis abnormal
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Anaemia, Anorexia, Brain oedema, Disseminated intravascular coagulation, Haemolysis
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Leukocytosis, Pyrexia, Somnolence, Stupor, Subarachnoid haemorrhage
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Urinary tract infection
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 0.08
Sex: F
Vaccine: DTPHIB, HIBV, OPV, DTPHIB, OPV, DTPHIB, HEP, OPV, DTPHIB, HIBV, OPV, HEP
Symptoms: Irritability, Otitis media
Clinical narrative: Between 5 and 6 wks of age, pt was admitted to the hospital for increased irritability and to rule out possible sepsis or meningitis. She was treated with a combination of ampicillin and Claforan. She recvd a loading dose and two subsequent doses of Claforan before it was discontinued the following day. Ampicillin was continued for 7 more days. The pt was discharged after 2 days with a diagnosis of possible otitis media. She was well at discharge. On follow-up, it was noted that the pt was the product of a unremarkable 40 week pregnancy and delivery and that her blood type was O, RH negative. The author of this article also reported that the pt had a reaction following vaccination with haemophilus b conjugate at four months of age. Follow-up information was received from one of the authors indicating that he did not feel the hep B vaccine "produced an adverse event in this patient."
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL, MMR, VARCEL
Symptoms: Ear disorder, Eyelid oedema, Rash, Rash macular, Respiratory rate increased
Clinical narrative: Child developed rash, grunting respiration at 44/min and swollen eye lids. Treated with Epi/diphenhydramine/O2.
Age: 1.0
Sex: M
Vaccine: MMR, VARCEL, MMR, VARCEL
Symptoms: Eyelid oedema, Grunting, Rash
Clinical narrative: Child developed rash, grunting respiration at 44/min and swollen eye lids. Treated with Epi/diphenhydramine/O2.
Age: 0.3
Sex: M
Vaccine: DTAP, HBHEPB, IPV, PNC
Symptoms: Coma
Clinical narrative: Pt found unresponsive by baby sitter on 7/17/01. He was taken to ER and pronounced DOA. Unknown reason for death at this time.  COD as per autopsy report-- undeterminable
Sex: F
Vaccine: VARCEL
Symptoms: Abortion spontaneous
Clinical narrative: Information has been received from a health professional concerning a female who was vaccinated with varicella virus vaccine live. At the time of vaccination, lab evaluation had revealed a negative pregnancy test. Approx. 2 weeks, post vax, the pt told the physician she was pregnant. Approx. 4-6 weeks later, the pt had a miscarriage. Medical attention was sought. No further information is available.