Age: 28.0
Sex: M
Vaccine: TYP
Symptoms: Product administration error, Product storage error
Clinical narrative: The patient left Vivotif in the car with an ice pack for 4 hours, the icepack partially melted, maximum temperature was 50 degrees of Fahrenheit or 45 degrees of Celsius and the patient started immunization and is in the third dose; The patient left Vivotif in the car with an ice pack for 4 hours, the icepack partially melted, maximum temperature was 50 degrees of Fahrenheit or 45 degrees of Celsius and the patient started immunization and is in the third dose; Case reference number US-BN-2023-010710 is a spontaneous case report initially received from a physician via Communication (reference number: USBAV23-2124) on 19-Dec-2023 and concerns a *28-year-old male patient*.  *The patient had no relevant medical history and was not taking any concomitant medications.*  On *15-Dec-2023*, the patient took the first dose of Vivotif (*batch number: 3003830, expiration date: 28-Feb-2024*) *at a dose of one dosage form, orally for typhoid fever*.  On *17-Dec-2023, two days after the first dose of Vivotif*, the patient took the second dose of Vivotif (*batch number: 3003830, expiration date: 28-Feb-2024*) *at a dose of one dosage form, orally*.  On *19-Dec-2023, four days after the first dose of Vivotif*, the patient took the third dose of Vivotif (batch number: 3003830, *expiration date: 28-Feb-2024*) *at a dose of one dosage form, orally*. As reported, the patient left Vivotif in the car with an ice pack for four hours and the ice pack partially melted. It was also reported that it was the wintertime, so the outside temperature was not hot, the maximum temperature of Vivotif was 50-degree Fahrenheit and *or 45 degrees of Celsius* (explicitly coded as 'product storage error' and 'product administration error').   *At the time of follow up report, the patient did not experience any adverse events during or after vaccination with Vivotif*.  All follow-up information is blended into the case narrative above, with the latest information presented between asterisks (*).  Follow-up information received from a physician on 29-Dec-2023: New information included patient demographic details (initials, age, gender, date of birth), confirmation that the patient had no relevant medical history and was not taking any concomitant medications, dosing details of the first, second and third dose of Vivotif, more information regarding temperature excursion and confirmation that the patient did not experience any adverse events during or after vaccination with Vivotif.; Reporter's Comments: A 28-year-old male patient left Vivotif in the car with an ice pack for four hours and the ice pack partially melted. It was also reported that it was the wintertime, so the outside temperature was not hot and the maximum temperature of Vivotif was 50-degree Fahrenheit, after which the patient took that third dose of Vivotif, which is considered as product storage error and product administration error. The patient did not experience any adverse event due to Vivotif vaccine. Product storage error and product administration error are considered as listed per company convention. The patient had no relevant medical history and was not taking any concomitant medications. Product storage error and product administration error have been considered as not related to the suspect vaccine, but to a human factor. This case is considered as non-serious.; Sender's Comments: A 28-year-old male patient left Vivotif in the car with an ice pack for four hours and the ice pack partially melted. It was also reported that it was the wintertime, so the outside temperature was not hot and the maximum temperature of Vivotif was 50-degree Fahrenheit, after which the patient took that third dose of Vivotif, which is considered as product storage error and product administration error. The patient did not experience any adverse event due to Vivotif vaccine. Product storage error and product administration error are considered as listed per company convention. The patient had no relevant medical history and was not taking any concomitant medications. Product storage error and product administration error have been considered as not related to the suspect vaccine, but to a human factor. This case is considered as non-serious.