Age: 37.0
Sex: F
Vaccine: COVID19
Symptoms: Urticaria
Clinical narrative: Hives; The initial safety information received was reporting only non-serious adverse drug reaction. Upon receipt of follow-up information on 20Aug2021, this case now contains serious adverse reaction. Information processed together.  This is a spontaneous report from a contactable consumer (the patient). A 37-year-old female patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, Lot Number: EW0164), intramuscular, administered in the left arm on 02Jun2021 09:00 as dose 2, single (age at vaccination 37-years-old) for COVID-19 immunization. The patient's medical history included COVID-19 prior to vaccination. The patient was not pregnant at the time of vaccination. The patient had no known allergies. Concomitant medications included: norethisterone (NORLYDA), loratadine, famotidine (PEPCID AC) all taken for an unspecified indication, start and stop date were not reported. The patient previously received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, Lot Number: EW0164), intramuscular, administered in the left arm on 12May2021 08:45 as dose 1, single (age at vaccination 37-years-old) for COVID-19 immunization. The patient had poison ivy on 29May2021 until 06Jun2021. The patient did not receive any other vaccines within four weeks prior to the vaccination. The patient had a very bad case of poison ivy when she received her second vaccine dose. The patient stated that on the Sunday, after her vaccine, on 06Jun2021 04:00, she woke up with hives all over her torso. By Monday, they were from the soles of her feet to the top of her head. They were very itchy and red. She ended up getting a steroid injection and steroid taper pack Monday. That definitely helped, but she ended up having to take another taper pack a week later. They knocked them out but then they came back another week later. They were still lingering over a month later. On 20Aug2021, the patient reported she had no side effects from her second dose until 5 days (as reported) after the dose. She woke up Sunday morning (06Jun2021 04:00) with her torso covered in hives. She had never had hives before, and they were very itchy. She had a bad case of poison ivy where she got the second dose, so she thought her immune system may have been over stimulated. The next day, the hives were from the bottom of her feet to the top of her head. She went to the urgent care, and they gave her a steroid injection plus taper pack. That helped, but 1 week after the steroids were done, she still had hives between her fingers and toes. She took another taper pack. Then they mostly went away. Then another week later, she went swimming and the "clame" in the pool must have aggravated her skin, and she got hives again. She has been taking loratadine and famotidine in double dose for the past 5 weeks. Two weeks into that regimen, the hives went away. Treatment was also reported as 2 courses of steroids plus high dosage antihistamine. The patient reported hives as an important medical event. The clinical outcome hives was recovered with sequelae on 30Jul2021. Since the vaccination, the patient had not been tested for COVID-19.