Age: 52.0
Sex: F
Vaccine: VARZOS
Symptoms: Antibody test, Chills, Feeling abnormal, Immediate post-injection reaction, Malaise
Clinical narrative: she felt horrible; immediately felt the worst pain in her left arm/ pain; immediately got sick/ got sicker and sicker throughout the day; sick with a low grade fever/ fever; had chills; had a rash that started on her left hand between her thumb and pointer finger, and then was on both hands, went up both arms, was on her torso, and her chest; rash looked like a chicken pox rash; Itchy/ itchy rash; This non-serious case was reported by a consumer via call center representative and described the occurrence of pain in arm in a 52-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Varicella vaccine (received 2 doses about 20 years ago on an unknown date). Additional patient notes included patient never had chicken pox.   On 03-NOV-2023, the patient received the 1st dose of Shingrix (left arm) .5 ml. On 03-NOV-2023, immediately after receiving Shingrix, the patient experienced pain in arm (Verbatim: immediately felt the worst pain in her left arm/ pain), sickness (Verbatim: immediately got sick/ got sicker and sicker throughout the day), low grade fever (Verbatim: sick with a low grade fever/ fever) and chills (Verbatim: had chills). On 05-NOV-2023, the patient experienced feels awful (Verbatim: she felt horrible). In NOV-2023, the patient experienced rash (Verbatim: had a rash that started on her left hand between her thumb and pointer finger, and then was on both hands, went up both arms, was on her torso, and her chest), varicella-like rash (Verbatim: rash looked like a chicken pox rash) and itchy rash (Verbatim: Itchy/ itchy rash). The patient was treated with paracetamol (Tylenol Extra Strength). The outcome of the pain in arm and itchy rash were resolving and the outcome of the sickness, low grade fever, chills and feels awful were resolved and the outcome of the rash and varicella-like rash were not resolved.   It was unknown if the reporter considered the pain in arm, sickness, low grade fever, chills, rash, varicella-like rash, itchy rash and feels awful to be related to Shingrix.     It was unknown if the company considered the pain in arm, sickness, low grade fever, chills, rash, varicella-like rash, itchy rash and feels awful to be related to Shingrix.   Additional Information: GSK receipt date: 13-NOV-2023 The patient self-reported this case. The patient reported that she received the 1st dose of Shingrix in her left arm in the morning and immediately felt the worst pain in her left arm and almost immediately got sick with a low-grade fever of maybe 100 Fahrenheit (patient did not take her temperature), had chills, and got sicker and sicker throughout the day. The patient reported that about 15 to 16 hours after the 1st dose of Shingrix, she had a rash that started on her left hand between her thumb and pointer finger, and then was on both hands, went up both arms, was on her torso, and her chest. The patient said the rash looked like a chicken pox rash, was itchy and was 3 dimensional. The patient reported the rash was all gone except one place on her hand today (on the day of reporting), and today that one place was dried up and looks like it would go away.  The patient reported she felt fine now (on the day of reporting). The patient reported that she never had chicken pox, and she received 2 doses of the Varicella vaccine (unknown product information) and wanted to report that her physician checked her titers and told her she was immune to chicken pox.  The patient reported that she took 2 Extra Strength Tylenol (no further product information) on Sunday, 5-NOV-2023, 2 days after because she felt horrible. Less than a day after received Shingrix, patient had chills. The event sickness, low grade fever, chills and feels awful were resolved in NOV-2023. The reporter consented to follow up.