Age: 70.0
Sex: F
Vaccine: COVID19
Symptoms: Accidental underdose, Bone pain, Chills, Hyperhidrosis, Vaccination site inflammation
Clinical narrative: I received 50mcg booster rather than 100mcg 3rd full dose, i am immunocompromised; Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm; This spontaneous case was reported by a nurse and describes the occurrence of HYPERHIDROSIS (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), BONE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE WARMTH (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE INFLAMMATION (experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm) and VACCINATION SITE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm) in a 70-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Waldenstrom's macroglobulinaemia (This diagnosis occurred prior to receiving the vaccine however it renders her immunocompromised) and Immunocompromised. Concomitant products included BENDAMUSTINE, RITUXIMAB, BUPRENORPHINE HYDROCHLORIDE (BELBUCA), LISINOPRIL, OXYCODONE and SODIUM BICARBONATE for an unknown indication.   In March 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In April 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 10-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 50 mcg. On 10-Dec-2021, the patient experienced ACCIDENTAL UNDERDOSE (I received 50mcg booster rather than 100mcg 3rd full dose, i am immunocompromised). In December 2021, the patient experienced HYPERHIDROSIS (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), BONE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE WARMTH (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE INFLAMMATION (experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm) and CHILLS (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm). On 10-Dec-2021, ACCIDENTAL UNDERDOSE (I received 50mcg booster rather than 100mcg 3rd full dose, i am immunocompromised) had resolved. At the time of the report, HYPERHIDROSIS (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), BONE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE WARMTH (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE INFLAMMATION (experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm), VACCINATION SITE PAIN (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm) and CHILLS (Experiencing chills, sweating, bone pain, inflammation at the site of injection with soreness which felt warm) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No treatment information was provided  The patient stated that the symptoms are ongoing.