Age: 42.0
Sex: M
Vaccine: COVID19, COVID19
Symptoms: Arthralgia, Burning sensation, Central nervous system inflammation, Mobility decreased, Pain in extremity
Clinical narrative: Central nervous system inflammation; Burning sensation; Mobility decreased; Pain in extremity; The joints in my hands particularly my right index finger, ring finger and thumb felt incredibly painful; This case was received via  FDA VAERS (Reference number: 1198418) on 08-Jun-2021 and was forwarded to Moderna on 08-Jun-2021.    This regulatory authority case was reported by a health care professional and describes the occurrence of CENTRAL NERVOUS SYSTEM INFLAMMATION (Central nervous system inflammation) in a 42-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 012L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Lyme's disease. Concurrent medical conditions included Lyme's disease.    On 14-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 14-Jan-2021, the patient experienced CENTRAL NERVOUS SYSTEM INFLAMMATION (Central nervous system inflammation) (seriousness criterion medically significant), BURNING SENSATION (Burning sensation), MOBILITY DECREASED (Mobility decreased) and PAIN IN EXTREMITY (Pain in extremity). 14-Jan-2021, the patient experienced ARTHRALGIA (The joints in my hands particularly my right index finger, ring finger and thumb felt incredibly painful). At the time of the report, CENTRAL NERVOUS SYSTEM INFLAMMATION (Central nervous system inflammation), BURNING SENSATION (Burning sensation), MOBILITY DECREASED (Mobility decreased) and PAIN IN EXTREMITY (Pain in extremity) had resolved and ARTHRALGIA (The joints in my hands particularly my right index finger, ring finger and thumb felt incredibly painful) was resolving.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   On 14 Jan 2021, at about 8:00pm, the patient had experienced nerve inflammation. He had pain in his right arm, it was a fiery electrical pain that radiated from his right shoulder down to his right hand. The joints in his hands particularly his right index finger, ring finger and thumb felt incredibly painful. He could not pick up or grasp anything. It felt like he had intense rheumatoid arthritis and his symptoms lasted about 5-6 days before they started to go away. No Treatment medication was provided.  Based on the current available information and temporal association between the use of the product and the events, a causal relationship cannot be excluded.  Event terms, onset dates and outcomes captured per SD Authority reporting. Event of arthralgia added with outcome of resolving.  Events seriousness IME list.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the events, a causal relationship cannot be excluded.  Event terms, onset dates and outcomes captured per SD Authority reporting. Event of arthralgia added with outcome of resolving.  Events seriousness IME list