Age: 65.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site pain, Injection site pruritus, Injection site swelling, Pruritus
Clinical narrative: developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area; developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area; developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area; had itching at the injection site; had swelling at the injection site; had pain at the injection site; had a fist-sized area of redness at the injection site; itching; This non-serious case was reported by a consumer via call center representative and described the occurrence of injection site itching in a 65-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included knee replacement. Concurrent medical conditions included chronic pain and chronic kidney disease.   On 20-FEB-2024, the patient received the 1st dose of Shingrix (intramuscular, right deltoid). On 20-FEB-2024, less than a day after receiving Shingrix, the patient experienced injection site itching (Verbatim: had itching at the injection site), injection site swelling (Verbatim: had swelling at the injection site), injection site pain (Verbatim: had pain at the injection site), injection site erythema (Verbatim: had a fist-sized area of redness at the injection site) and pruritus (Verbatim: itching). On 23-FEB-2024, the patient experienced raised rash (Verbatim: developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area), rash urticaria-like (Verbatim: developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area) and itchy rash (Verbatim: developed an itchy rash (described as raised and welty) all over her right side on her hip, groin area, stomach and breast area). The patient was treated with acrivastine (Benadryl). The outcome of the injection site itching, injection site swelling, injection site pain and injection site erythema were resolved and the outcome of the pruritus was not resolved and the outcome of the raised rash, rash urticaria-like and itchy rash were resolving.   It was unknown if the reporter considered the injection site itching, injection site swelling, injection site pain, injection site erythema, pruritus, raised rash, rash urticaria-like and itchy rash to be related to Shingrix.     It was unknown if the company considered the injection site itching, injection site swelling, injection site pain, injection site erythema, pruritus, raised rash, rash urticaria-like and itchy rash to be related to Shingrix.   Additional Information: GSK Receipt Date: 13-MAR-2024 The patient was self-reported this case. The patient reported that she received Shingrix vaccine and soon after the vaccination she had pain, itching, swelling and a fist-sized area of redness at the injection. The reporter stated that about three days after the vaccination she developed itchy rash which was described as raised rash and welty rash, this rash spread all over her right side on her hip, groin area, stomach and breast area and about a week after rash spread to both of her elbows, thighs, and middle of back. The patient stated injection site reactions were resolved but she still had the rash which had decreased. The itchiness continued and she used Benadryl as treatment for itchiness. The reporter consented to follow up.