Age: 42.0
Sex: M
Vaccine: COVID19
Symptoms: Body temperature abnormal, Chills, Impaired healing, Joint swelling, Musculoskeletal disorder
Clinical narrative: Swelling in right wrist; Swelling in right pinky finger; Anytime when got a bug bite or tick bite it was slow to heal; Anytime when got a bug bite or tick bite it was slow to heal; Itching on hands and the bottom of feet/only thing had was a hamburger; Feet and palms started itching; Pain in right wrist; Flared again in joints after second injection of COVID vaccine; Temperature was 102 with chills after second COVID vaccine; Lost the use of his right hand and fingers on his left hand; Temperature was 102 with chills after second COVID vaccine; This spontaneous case was reported by a consumer and describes the occurrence of ARTHROPATHY (Flared again in joints after second injection of COVID vaccine), JOINT SWELLING (Swelling in right wrist), PERIPHERAL SWELLING (Swelling in right pinky finger), BODY TEMPERATURE ABNORMAL (Temperature was 102 with chills after second COVID vaccine) and ARTHROPOD BITE (Anytime when got a bug bite or tick bite it was slow to heal) in a 42-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) for Psoriatic arthritis and Plaque psoriasis.    The patient's past medical history included COVID-19 (Hospitalized for five days, Humira and stopped) on 09-Jul-2021 and Psoriasis flare-up (Psoriasis came back when patient decided to stop the treatment.). Concomitant products included CYCLOBENZAPRINE HCL, CALCITRIOL, TRAMADOL HCL, CLOBETASOL PROPIONATE, NAPROXEN and MULTIVITAMIN [VITAMINS NOS] for an unknown indication.   In 2012, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) 40 milligram every two weeks. On 22-Oct-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Nov-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 13-Dec-2021, ADALIMUMAB (HUMIRA) (Subcutaneous) dosage was changed to 40 milligram every two weeks. In November 2021, the patient experienced ARTHROPATHY (Flared again in joints after second injection of COVID vaccine), BODY TEMPERATURE ABNORMAL (Temperature was 102 with chills after second COVID vaccine), MUSCULOSKELETAL DISORDER (Lost the use of his right hand and fingers on his left hand) and CHILLS (Temperature was 102 with chills after second COVID vaccine). In December 2021, the patient experienced PRURITUS (Feet and palms started itching) and ARTHRALGIA (Pain in right wrist). On 17-Dec-2021, the patient experienced ADVERSE FOOD REACTION (Itching on hands and the bottom of feet/only thing had was a hamburger). On an unknown date, the patient experienced JOINT SWELLING (Swelling in right wrist), PERIPHERAL SWELLING (Swelling in right pinky finger), ARTHROPOD BITE (Anytime when got a bug bite or tick bite it was slow to heal) and IMPAIRED HEALING (Anytime when got a bug bite or tick bite it was slow to heal). The patient was treated with GABAPENTIN at an unspecified dose and frequency. At the time of the report, ARTHROPATHY (Flared again in joints after second injection of COVID vaccine), PRURITUS (Feet and palms started itching) and ADVERSE FOOD REACTION (Itching on hands and the bottom of feet/only thing had was a hamburger) had resolved, JOINT SWELLING (Swelling in right wrist) and PERIPHERAL SWELLING (Swelling in right pinky finger) had not resolved, BODY TEMPERATURE ABNORMAL (Temperature was 102 with chills after second COVID vaccine), ARTHROPOD BITE (Anytime when got a bug bite or tick bite it was slow to heal), IMPAIRED HEALING (Anytime when got a bug bite or tick bite it was slow to heal) and CHILLS (Temperature was 102 with chills after second COVID vaccine) outcome was unknown and MUSCULOSKELETAL DISORDER (Lost the use of his right hand and fingers on his left hand) and ARTHRALGIA (Pain in right wrist) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In November 2021, Body temperature: 102, unit not reported. In December 2021, Pain assessment: 4 out of 10. On an unknown date, Pain assessment: 10 out of 10.         The co-suspect Humira concentration was reported as 40 MG/0.4 ML and formulation was reported as solution for injection in pre-filled pen. On 17-Dec-2021, patient had a hamburger and started itching on his hands and bottom of feet. Patient went to sleep by taking Benadryl and Gabapentin and it went away. On 27-Dec-2021, he took Humira injection and did not had that reaction so, patient was unsure if it was Humira. Since, patient had restarted Humira his pain from ten out of ten had gone to four out of ten however, still had pain in his wrist but it was better and also regained the function of right hand and some fingers on left hand.  It was unknown if patient was enrolled n a COVID-19 Vaccine Trial.  The patient was treated with Benadryl.  The reporter causality for the events Temperature was 102 with chills after second COVID vaccine, lost the use of right hand and fingers on left hand, pain in wrist, itching on hands and the bottom of feet/only thing had was a Hamburger, anytime when got a bug bite or tick bite it was slow to heal with co-suspect Humira was not provided. The reporter causality for the events feet and palms started itching, swelling in right wrist, flared again in joints after second injection of COVID vaccine and swelling in right pinky finger with co-suspect Humira was no reasonable possibility.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.   This case was linked to MOD-2022-623582 (Patient Link).