Age: 25.0
Sex: F
Vaccine: HPV4
Symptoms: Ovarian remnant syndrome, Pain, Pelvic floor dysfunction, Pelvic pain, Premature menopause
Clinical narrative: endometriosis/gynecologic injuries (pain prior to and during menstruation, periods became much heavier and were prolonged); Pseudo cerebri/pseudotumor cerebri; Autonomic injuries; She had excess fluid on her brain; fibromyalgia/neurological injuries (whole body pain); Ovarian remnant syndrome/gynecologic Injuries (severe pelvic pain); Premature menopause; Pelvic floor syndrome; numbness in the left side of her face; Autoimmune injuries; Information has been received from a lawyer, regarding a case in litigation and concerning an adult female patient (pt) of an unknown age. No information concerning the pt's medical history, concurrent conditions or concomitant medications was provided. On an unknown date, at the age of 25 years old, as recommended by the physician, the pt received her first dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported) for preventing cervical cancer. On an unknown date, at the age of 26 years old, the pt received her second dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported). On an unknown days, following her quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccinations, the pt began experiencing excruciating pain prior to and during menstruation. Up to this point, her periods had been completely normal. The pain was debilitating and never stopped. Pt's periods became much heavier and were prolonged. She was diagnosed with endometriosis via laparoscopic surgery. She thereafter had to undergo a partial hysterectomy and later had a second hysterectomy to remove her remaining reproductive organs. Pt also experienced numbness in the left side of her face and went to the emergency room (ER) where she was told she had excess fluid on her brain. She was diagnosed with pseudo cerebri. On an unknown date, reported as thereafter, she experienced whole body pain to the point she was unable to lift her arms and suffered severe pelvic pain. She was diagnosed with fibromyalgia and ovarian remnant syndrome. She experienced and at the time of the report continued to experience premature menopause. As the months progressed, so did the pt's injuries. She was seen by multiple physicians and specialists for her complaints. The pt did not know and had no reason to know that her symptoms were caused by the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, as no information to the contrary was given to her by her medical providers. It was not until early 2023 that pt began to suspect that quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) could be the cause of her symptoms and injuries. As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, pt has been unable to engage in activities that a normal young person would enjoy. She continued to experience pain, which made it difficult to stand for long periods of time, which is a necessity for her job, and her symptoms interfere with her ability to engage in activities with her teenage daughter. She also continued to experience the symptoms of premature menopause. On unknown dates, based upon her chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt was diagnosed with various medical conditions, including but not limited to endometriosis, fibromyalgia, pseudotumor cerebri, ovarian remnant syndrome and pelvic floor syndrome. As a result of receiving quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, pt sustained serious and debilitating injuries, including but not limited to autonomic, autoimmune, and neurological injuries and resulting sequalae. The pt contended that her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune and gynecologic injuries, including but not limited to endometriosis, fibromyalgia, pseudotumor cerebri, ovarian remnant syndrome and pelvic floor syndrome, as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which were alleged herein and all of which were caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. The pt had suffered and at the time of report continued to suffer severe and permanent physical injuries, and associated symptomatology and had suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her autoimmune disease and other injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the pt suffered and at the time of report continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of the events was considered to be not recovered. The reporter considered the events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL).  The events were considered to be disabling.  Upon internal review, the events of endometriosis (due to medically significant treatment of hysterectomy), pseudotumor cerebri, autonomic injuries, and autoimmune injuries were determined to be medically significant.