Age: 27.0
Sex: F
Vaccine: FLU4
Symptoms: Chest discomfort, Chest pain, Dyspnoea, Migraine with aura
Clinical narrative: Shortness of breath upon exertion; Chest pain and tightness; Chest pain and tightness; Migraine with visual aura; This spontaneous case was received on 11-Oct-2020 from other non-health professional via Health Authority (reference number: SEQW20-03357) and concerned a 27-year-old, female patient.  The patient's past medical history included migraines. The patient's concomitant medications included buspirone, bupropion, Albuterol (salbutamol), and rizatriptan.  On 10-Oct-2020, the patient was vaccinated with Afluria Quadrivalent (influenza vaccine, dose: 0.5 ml, route of administration: intramuscular; anatomical location: deltoid) for influenza prophylaxis. The batch number reported was P100255594. This was the first influenza vaccine the patient received.  On the same day, two hours after receiving Afluria Quadrivalent, the patient experienced chest pain and tightness and shortness of breath upon exertion. In the evening the patient experienced migraine with visual aura. Physician advised the patient to use Albuterol inhaler and take Tylenol (paracetamol).  On an unknown date in Oct-2020, the patient recovered from the event of 'migraine with aura'.  At the time of initial reporting on 11-Oct-2020, the patient had not recovered from the events 'shortness of breath', 'chest pain' and 'chest tightness', as it was reported that the patient continued to experience symptoms.  The reporter did not provide a causality assessment.  The reporter assessed the events as non-serious.  Company comment: A 27-year-old, female patient, was administered Afluria Quadrivalent vaccine. On the same day, two hours after receiving vaccine, the patient experienced chest pain, chest discomfort and dyspnoea exertional. In the evening the patient experienced migraine with visual aura. The patient's past medical history included migraines. The patient's concomitant medications included buspirone, bupropion, Albuterol (salbutamol), and rizatriptan. Causality was highly confounded by concomitant medications. However, causal role of the suspect vaccine cannot be excluded due to plausible chronology and is assessed as unlikely related for chest pain, chest discomfort and dyspnoea exertional. (defaults to "related" in the safety database for reporting purposes) Causality is assessed as not related for migraine with visual aura.; Sender's Comments: A 27-year-old, female patient, was administered Afluria Quadrivalent vaccine. On the same day, two hours after receiving vaccine, the patient experienced chest pain, chest discomfort and dyspnoea exertional. In the evening the patient experienced migraine with visual aura. The patient's past medical history included migraines. The patient's concomitant medications included buspirone, bupropion, Albuterol (salbutamol), and rizatriptan. Causality was highly confounded by concomitant medications. However, causal role of the suspect vaccine cannot be excluded due to plausible chronology and is assessed as unlikely related for chest pain, chest discomfort and dyspnoea exertional. (defaults to "related" in the safety database for reporting purposes) Causality is assessed as not related for migraine with visual aura.