Age: 58.0
Sex: F
Vaccine: FLUR4, VARZOS
Symptoms: Headache, Nausea, Pain, Paraesthesia
Clinical narrative: 9:30 am: Received 2 vaccines at Pharmacy, prescribed by the pharmacist: a) Shingrix Vial Kit, NDC 58160-0823011,  and b) Flublok Quad 2020-2021, NDC 49281-0729-10.  Pharmacist was very professional in his administration of both vaccines into left deltoid. I had no questions. I understood that there could be some side effects of both vaccines. He gave me the required literature.    3:45 pm I started feeling chills and aches. I checked the literature and noted that these symptoms are common.   4:30 pm Aches and chills increased. Temperature: 97.7.  5:00 pm Went to bed and noticed some unmistakable symptoms of genital herpes prodrome. My first diagnosis of Shingles occurred in 1990, with full blown fatigue symptoms and skin pain, a rash on left hip and overall nerve inflammation. I was diagnosed with genital herpes in 2003, with the onset of flu-like symptoms and a lesion, diagnosed by a healthcare provider. I was prescribed Valtrex in 2003, and have always kept a prescription of that, or Acyclovir, (switched to Acyclovir around 2014) on hand, at 400 ml, in case I felt symptoms onset of either Shingles or genital herpes. The tingling nerve sensation is unmistakable. I have not had a full outbreak of genital herpes since 2003, but perhaps 10 instances since then when I used the antiviral, with a 3 to 5 day course, 2xs per day, and symptoms resolved, never as severe as onset.  At 5:00 pm, I noted the suspected symptoms, and also felt familiar, uncomfortable symptoms of Shingles in the lower back and down the leg nerves.  I wondered if rest would cure the symptoms and chills, so I feel asleep under covers.   6:00  pm Awoke with a headache, slight dizziness, slight nausea, (all verified as common side effects of either vaccine)  and more frequent tingling of genital herpes. I consulted a few web sources and blogs to see if anyone else had experienced a triggering effect from vaccines. Indeed, there were experiential reports, as well as medical literature that does not show a reliable connection. One thing seemed true: the vaccines are strong, and in combination, perhaps both vaccines overwhelmed my immune system. The times in the past when I felt outbreaks came with some rather stressful event (a death, a car accident, traveling too much for work) or prolonged lack of sleep. I understand that the two viruses are different but that stress could trigger either.  I have been careful to minimize stress since learning about these triggers.   6:30 pm I decided to take an Acyclovir, hoping that it would not interfere with the Shinglex vaccine, assuming the molecular interaction would be different. I also ate a light dinner and drank water, despite mild nausea.   7:15 pm Temperature 100.5  7:30 pm Got back in bed to rest, and wrote this report.   8:45 pm The symptoms now are a consistent low level nerve tingling from lower back, down both legs, a slight throbbing sensation within vagina, general body aches, about a 2.5 on the pain scale; not painful but noticeably uncomfortable, and feeling the need to rest and stay warm. Chills have subsided, nausea has reduced to a minor stomach churning, (no vomiting), minor headache remains. I am warm, but not sweating. I have no respiratory symptoms.   This does not seem related to Covid without any respiratory symptoms. No sore throat, no trouble breathing at the present time. I have not had a Covid test but have been careful to wear 2 masks and gloves when going to the market, and have kept distance from people unknown to me. The two people have been within less than 6? proximity for short periods of time are both healthy and without symptoms.   9:00 pm Will take a second Acyclovir  400 ml, and 2 Acetominaphen, 500 ml, and attempt to sleep after filing this report.