Age: 67.0
Sex: F
Vaccine: COVID19
Symptoms: Antibody test, Antibody test abnormal, Extra dose administered, Inappropriate schedule of product administration
Clinical narrative: her antibody level was checked again and this time it had decreased to 236/ another booster shot of Moderna, after which her antibody level was 74; Patient's antibody levels have decreased despite getting multiple booster shots; receive another booster shot of Moderna; This spontaneous case was reported by a physician and describes the occurrence of ANTIBODY TEST ABNORMAL (her antibody level was checked again and this time it had decreased to 236/ another booster shot of Moderna, after which her antibody level was 74), INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient's antibody levels have decreased despite getting multiple booster shots) and EXTRA DOSE ADMINISTERED (receive another booster shot of Moderna) in a 67-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     No Medical history reported.    On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced ANTIBODY TEST ABNORMAL (her antibody level was checked again and this time it had decreased to 236/ another booster shot of Moderna, after which her antibody level was 74), INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient's antibody levels have decreased despite getting multiple booster shots) and EXTRA DOSE ADMINISTERED (receive another booster shot of Moderna). At the time of the report, ANTIBODY TEST ABNORMAL (her antibody level was checked again and this time it had decreased to 236/ another booster shot of Moderna, after which her antibody level was 74) had not resolved and INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (Patient's antibody levels have decreased despite getting multiple booster shots) and EXTRA DOSE ADMINISTERED (receive another booster shot of Moderna) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Antibody test: 236 (Low) decreased to 236, 74 (Low) level was 74, 392 392 and 61 (Low) 61.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   The physician reported that the patient has received the primary series of the Moderna COVID-19 vaccine and after 8 months receiving the 2nd dose, her antibody level was measured which came out to 392. The patient received the booster dose after 3 month from 2nd dose. The patient then decided to receive a Pfizer COVID-19 booster after which her antibody level fell down to 61. The physician is shocked and does not understand what is going on with this patient. He is not sure if there is some sort of immune tolerance that this patient has developed and that is causing a steady decline in antibody levels no matter the number of boosters the patient is getting No concomitant medication reported. No treatment medication details reported.