Age: 48.0
Sex: M
Vaccine: DTAP, DTAP, HIBV, IPV, PNC, VARZOS
Symptoms: Herpes zoster, Off label use, Product administered to patient of inappropriate age, Product use in unapproved indication, Skin lesion
Clinical narrative: Shingles; active lesions.; is 48 years old but stated that he had a medical condition that warranted receiving Shingrix before age 50 therefore; is 48 years old but stated that he had a medical condition that warranted receiving Shingrix before age 50 therefore; if the patient was administered with Infanrix / inappropriate age at vaccine administration; This case was reported by a physician via call center representative and described the occurrence of shingles in a 48-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Hib (Hiberix) for prophylaxis, PNEUMOCOCCAL VACCINE (PREVNAR) for prophylaxis, DIPHTHERIA TOXOID + PERTUSSIS TOXOID + TETANUS TOXOID (DAPTACEL) for prophylaxis, POLIOMYELITIS VACCINE INACTIVATED (IPV VACCINE) for prophylaxis, DTPa (Infanrix) for prophylaxis and dtpa vaccine pre-filled syringe device (Infanrix Pre-Filled Syringe Device) injection syringe for prophylaxis.   On 15th December 2021, the patient received the 1st dose of Shingrix (intramuscular) 50 µg, Hiberix, PREVNAR, DAPTACEL, IPV VACCINE, Infanrix and Infanrix Pre-Filled Syringe Device. On 15th December 2021, unknown after receiving Shingrix and not applicable after receiving Hiberix, Infanrix and Infanrix Pre-Filled Syringe Device, the patient experienced off label use, drug use for unapproved indication and inappropriate age at vaccine administration. On 24th December 2021, the patient experienced shingles and skin lesion. On an unknown date, the outcome of the shingles and skin lesion were not recovered/not resolved and the outcome of the off label use, drug use for unapproved indication and inappropriate age at vaccine administration were unknown.   It was unknown if the reporter considered the shingles and skin lesion to be related to Shingrix, Hiberix, Infanrix and Infanrix Pre-Filled Syringe Device. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences.  Additional details were provided as follows: The reporter was the patient and he is also a medical doctor. The patient received doses of Shingirx, DTaP, HIB, IPV, and Prevnar and experienced shingles. The patient was 48 years old but stated that he had a medical condition that warranted receiving Shingrix , which led to off label use, drug use for unapproved indication.  On the same day the patient received DTaP, HIB and Infanrix , which led to inappropriate age at vaccine administration. The reporter stated that he thought the name of the DTaP vaccine he was administered was Daptacel.  The reporter did not provide lot or expiration date of the vaccines administered. The reporter stated that on 24th December 2021, approximately 10 days after the vaccines, he developed shingles which was currently unresolved. he still had active lesions. The reporter also stated that if the patient was administered Hiberix or Infanrix (exact vaccines administered uncertain per patient) then that would be AE for inappropriate age.  The reporter did not want to provide his email. The reporter consented to follow-up.