Sex: M
Vaccine: HPV4, MNQ
Symptoms: Bradycardia, Hyperhidrosis, Hypotension, Loss of consciousness, Presyncope
Clinical narrative: Initial information received on 04-Oct-2018 regarding an unsolicited valid serious case received from a office staff. This case involves Adult male patient (age not reported), who experienced became hypotensive, nearsyncopal, loss of consciousness, episode with visual disturbance, bradycardic and diaphoretic, while he received vaccines GARDASIL and MENACTRA. The patient's past medical history, medical treatment(s), vaccination(s) and family history were not provided. Concomitant medications were not reported. On an unknown date, the patient received a dose of suspect MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE lot 06153AA. On an unknown date, the patient received a dose of suspect GARDASIL not produced by Sanofi Pasteur lot number not reported. On an unknown date, the patient developed a serious became hypotensive (hypotension) following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day. (hospitalization duration1 day). On an unknown date, the patient developed a serious nearsyncopal (presyncope) following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day. (hospitalization duration 1 day). On an unknown date, the patient developed a serious loss of consciousness  following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day. (hospitalization duration1 day). On an unknown date, the patient developed a serious episode with visual disturbance (visual impairment) following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day.. (hospitalization duration1 day). On an unknown date, the patient developed a serious bradycardic (bradycardia) following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day.. (hospitalization duration1 day). On an unknown date, the patient developed a serious diaphoretic (hyperhidrosis) following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of GARDASIL. The patient was hospitalized for this event for 1 day. (hospitalization duration1 day). Patient was visited to the emergency department. No Lab data was reported. Final diagnosis was diaphoretic, bradycardic, episode with visual disturbance, loss of consciousness, nearsyncopal and became hypotensive. It was not reported if the patient received a corrective treatment. The patient outcome is reported as Unknown for became hypotensive, as Unknown for nearsyncopal, as Unknown for loss of consciousness, as Unknown for episode with visual disturbance, as Unknown for bradycardic and as Unknown for diaphoretic. Documents held by the sender: none.; Sender's Comments: This case involves a patient of unknown age, who experienced nearsyncopal episode with hypotension, loss of consciousness, visual disturbance, bradycardia and diaphoretic post vaccination with GARDASIL and MENACTRA. Time to onset is unknown. Additional information including patient's medical condition at the time of vaccination, vaccination technique, laboratory investigations excluding other etiology would be needed to fully assess this case. Moreover, concomitant administration of two vaccines preceded the event. Based upon the reported information, the role of the vaccines cannot be individually assessed.