Age: 13.0
Sex: F
Vaccine: HPV4
Symptoms: Breast enlargement, Breast pain, Breast swelling, Chest discomfort, Chest pain
Clinical narrative: Postural Orthostatic Tachycardia (POTS)/dysaut/chest pain/tight,heart palpitations,fainting,dizziness,brain fog,blurred vision,nausea,diarrhea,headaches,dif breathing,numbness in arms,mscl weakness,GI issues,hot flashes/chil,low BP,fatigue,presyncope; joint dysfunction; amplified musculoskeletal pain syndrome/body pain/difficulty walking/numbness in arms; irregular menstrual cycle; swollen painful enlarged right breast; cysts on ovaries; constant migraines; autoimmune disorder; numbness in her face; Information has been received from a lawyer, regarding a case in litigation and concerning a female patient (pt). Prior to receiving the suspect vaccine, she was a healthy, alert, active, athletic child who did very well in school. She enjoyed writing, playing instruments and sports. No other information concerning the pt's medical history, concurrent conditions or concomitant medications was provided. On 09-NOV-2018, at the age of 13 years old, the pt received her first dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported) for preventing cervical cancer. On 28-MAY-2019, at the age of 14 years old, the pt received her second dose of quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) (dose, route of administration, anatomical location, lot # and expiration date were not reported). Following her second quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, the pt experienced chest tightness and pain, heart palpitations, fainting, dizziness upon standing, brain fog, difficulty concentrating, blurred vision, nausea, diarrhea, numbness in her face and arms, increased daily headaches, difficulty breathing and walking, body pain, muscle weakness, gastrointestinal issues, hot flashes, chills, low blood pressure, irregular menstrual cycle, swollen painful enlarged right breast, cysts on ovaries, and constant fatigue. She experienced episodes of presyncope when she would stand, walk, or sit upright for a long period. Eventually, due to her blood pressure dropping, she blacked out and fell down a concrete staircase in the student center at her high school. As the months progressed, so did the pt's symptoms. She was seen by multiple physicians and specialists for her complaints. The pt did not know and had no reason to know that her symptoms were caused by the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, as no information had been given to her by her medical providers to lead to that conclusion. It was not until late 2022 that the pt began to suspect that quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) was the cause of her symptoms and injuries. As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt was unable to engage in activities that a young person her age would enjoy. The pt's academic performance and social life has been negatively affected and has been challenging. She was an author, musician, artist, actress and youth model since age 6, since the quadrivalent human papillomavirus (HPV) (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccinations she can no longer concentrate on writing, she does not have the energy to play roles or model. She enjoyed playing tennis and running track. She was now unable to participate in any sports and/or physical activity due to difficulty breathing and walking, chest pains, heart palpitations, dizziness, muscle weakness, chronic fatigue, and constant migraines. On unknown dates, based upon her chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt was diagnosed with various medical conditions, including but not limited to, postural orthostatic tachycardia (POTS), dysautonomia, joint dysfunction, and amplified musculoskeletal pain syndrome. The pt contended that her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injection(s) caused her to develop serious and debilitating autoimmune injuries (also reported injuries), including but not limited to: postural orthostatic tachycardia (POTS), dysautonomia, joint dysfunction, and amplified musculoskeletal pain syndrome, as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which are alleged herein and all of which were caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder (also reported as autonomic, autoimmune, and neurological injuries and resulting sequalae that the pt sustained as a result of receiving the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine). The pt had suffered and at the time of report continued to suffer severe and permanent physical injuries, and associated symptomatology and had suffered severe and permanent emotional injuries, including pain and suffering. He also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her autonomic and autoimmune diseases and other injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of his quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the pt suffered and at the time of report continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and he would continue to incur these losses and expenses in the future.  The outcome of the events were considered to be not recovered. The lawyer considered all the events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL).  Upon internal review, the event of autoimmune disorder was determined to be medically significant. All the events were considered to be disabling.