Age: 66.0
Sex: F
Vaccine: COVID19
Symptoms: Logorrhoea, Myalgia, Product dose omission issue, Pyrexia
Clinical narrative: feeling terrible; Loss of taste; Loss of smell; not taking the 2nd dose of the Moderna vaccine; being sick; Super rush of adrenaline; flu-like symptoms; very dehydrated; Heart felt like it was being squeezed and twisted /Myheart felt like someone had grabbed it smooshed it and put it back in my chest; drenched from head to toe (3 blanket)/fever that made her sweat through her sheets/sweats; serum noradrenaline increased / feels like adrenaline is flowing, increased metabolism; being talkative / Very talkative; weakness; extreme fatigue; fever/fever that made her sweat through her sheets / Spiked fever; Headache; muscle aches; joint pain; chills; This spontaneous case was reported by a consumer and describes the occurrence of HYPERMETABOLISM (serum noradrenaline increased / feels like adrenaline is flowing, increased metabolism), LOGORRHOEA (being talkative / Very talkative), ASTHENIA (weakness), EPINEPHRINE INCREASED (Super rush of adrenaline) and HYPERHIDROSIS (drenched from head to toe (3 blanket)/fever that made her sweat through her sheets/sweats) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 012M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Asthma and Lupus syndrome. Concomitant products included HYDROCODONE for Pain, COLECALCIFEROL (VITAMIN D 3) and ZINC for Supplementation therapy, VITAMIN C [ASCORBIC ACID], PARACETAMOL (TYLENOL) and ASPIRIN [ACETYLSALICYLIC ACID] for an unknown indication.    On 28-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 28-Jan-2021, the patient experienced HYPERMETABOLISM (serum noradrenaline increased / feels like adrenaline is flowing, increased metabolism), LOGORRHOEA (being talkative / Very talkative), ASTHENIA (weakness), HYPERHIDROSIS (drenched from head to toe (3 blanket)/fever that made her sweat through her sheets/sweats), CHEST DISCOMFORT (Heart felt like it was being squeezed and twisted /Myheart felt like someone had grabbed it smooshed it and put it back in my chest), FATIGUE (extreme fatigue), PYREXIA (fever/fever that made her sweat through her sheets / Spiked fever), HEADACHE (Headache), MYALGIA (muscle aches), ARTHRALGIA (joint pain) and CHILLS (chills). On 30-Jan-2021, the patient experienced DEHYDRATION (very dehydrated). On an unknown date, the patient experienced EPINEPHRINE INCREASED (Super rush of adrenaline), INFLUENZA LIKE ILLNESS (flu-like symptoms), FEELING ABNORMAL (feeling terrible), AGEUSIA (Loss of taste), ANOSMIA (Loss of smell), PRODUCT DOSE OMISSION ISSUE (not taking the 2nd dose of the Moderna vaccine) and ILLNESS (being sick). On 30-Jan-2021, HYPERMETABOLISM (serum noradrenaline increased / feels like adrenaline is flowing, increased metabolism), LOGORRHOEA (being talkative / Very talkative), ASTHENIA (weakness), HYPERHIDROSIS (drenched from head to toe (3 blanket)/fever that made her sweat through her sheets/sweats), DEHYDRATION (very dehydrated), FATIGUE (extreme fatigue) and PYREXIA (fever/fever that made her sweat through her sheets / Spiked fever) had resolved, CHEST DISCOMFORT (Heart felt like it was being squeezed and twisted /Myheart felt like someone had grabbed it smooshed it and put it back in my chest), HEADACHE (Headache), MYALGIA (muscle aches), ARTHRALGIA (joint pain) and CHILLS (chills) outcome was unknown. At the time of the report, EPINEPHRINE INCREASED (Super rush of adrenaline), INFLUENZA LIKE ILLNESS (flu-like symptoms), FEELING ABNORMAL (feeling terrible), AGEUSIA (Loss of taste), ANOSMIA (Loss of smell) and ILLNESS (being sick) outcome was unknown and PRODUCT DOSE OMISSION ISSUE (not taking the 2nd dose of the Moderna vaccine) had resolved.        mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date.       Treatment for the event included Zithromax for 5 days Tylenol and Aspirin,Hydrocodone 375mg  Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.   Most recent FOLLOW-UP information incorporated above includes: On 26-Apr-2021: Significant follow up received on 26-4-2021, Patient demographics(Weight, Race ) added. New events (Loss of taste, Loss of smell, adrenaline rush, chest discomfort, Sweaty, Talkative) were added. Treatment medications(Tylenol, Aspirin, Azithromycin) added. Action taken with drug (Withdrawn) added. On 26-Apr-2021: Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.