Age: 24.0
Sex: F
Vaccine: COVID19, FLU3, UNK
Symptoms: Swelling face
Clinical narrative: drop in blood pressure; wheezing; having trouble breathing/difficulty breathing; suspected allergic reaction; swelling of the face and throat/facial and throat swelling; swelling of the face and throat/facial and throat swelling; bone and jaw pain; bone and jaw pain; flushing; sinus pain; This is a spontaneous report received from a Consumer or other non HCP.  A 24-year-old female patient (not pregnant) received BNT162b2 omicron (kp.2) (COMIRNATY (2024-2025 FORMULA)), on 10Sep2024 at 18:45 as dose 1, single (Batch/Lot number: unknown) at the age of 24 years, in right arm for covid-19 immunisation; influenza vaccine rha 3v (baculovirus) (FLUBLOK), on 10Sep2024 as dose number unknown, single), in right arm for immunisation. The patient's relevant medical history included: "Allergy: sulfa drugs" (unspecified if ongoing); "Allergy: bee venom" (unspecified if ongoing). Concomitant medication(s) included: ISOTRETINOIN, start date: 01Jul2024; SPRINTEC, start date: 06Aug2018; VITRON C [ASCORBIC ACID;FERROUS FUMARATE], start date: 06Jul2020. The following information was reported: BONE PAIN (hospitalization, life threatening), PAIN IN JAW (hospitalization, life threatening) all with onset 2024, outcome "not recovered" and all described as "bone and jaw pain"; FLUSHING (hospitalization, life threatening) with onset 2024, outcome "not recovered"; SINUS PAIN (hospitalization, life threatening) with onset 2024, outcome "not recovered"; BLOOD PRESSURE DECREASED (hospitalization, life threatening) with onset 10Sep2024 at 21:15, outcome "not recovered", described as "drop in blood pressure"; DYSPNOEA (hospitalization, life threatening) with onset 10Sep2024 at 21:15, outcome "not recovered", described as "having trouble breathing/difficulty breathing"; HYPERSENSITIVITY (hospitalization, life threatening) with onset 10Sep2024 at 21:15, outcome "not recovered", described as "suspected allergic reaction"; WHEEZING (hospitalization, life threatening) with onset 10Sep2024 at 21:15, outcome "not recovered"; SWELLING FACE (hospitalization, life threatening), PHARYNGEAL SWELLING (hospitalization, life threatening) all with onset Sep2024, outcome "not recovered" and all described as "swelling of the face and throat/facial and throat swelling". The clinical course was reported as follows: 2.5 hours after getting the vaccine patient experienced a drop in blood pressure and started wheezing and having trouble breathing. Patient went to the Emergency Room (ER) and she was treated for suspected allergic reaction. On 11Sep2024, it happened again and patient was admitted to the hospital and given epinephrine twice. The week after, patient had to go to the ER 4 times due to swelling of the face and throat. It had been almost a month since vaccination and patient had been taking 4x cetirizine, 60 mg prednisone, 2x famotidine, 1x montelukast and she still got facial and throat swelling. Patient also experienced bone and jaw pain, flushing, her right side got red, sinus pain, and difficulty breathing. Epinephrine, diphenhydramine, methylprednisolone, famotidine, oxygen was given as treatment. The patient was hospitalized for blood pressure decreased, wheezing, dyspnoea, hypersensitivity, swelling face, pharyngeal swelling, bone pain, pain in jaw, flushing, sinus pain (hospitalization duration: 2 day(s)). The events "drop in blood pressure", "wheezing", "having trouble breathing/difficulty breathing", "suspected allergic reaction" and "swelling of the face and throat/facial and throat swelling" required emergency room visit. Therapeutic measures were taken as a result of blood pressure decreased, wheezing, dyspnoea, hypersensitivity, swelling face, pharyngeal swelling, bone pain, pain in jaw, flushing, sinus pain.  The information on the batch/lot number for BNT162b2 omicron (kp.2) will be requested and submitted if and when received.