Sex: F
Vaccine: FLUX, FLU4
Symptoms: Abnormal behaviour, Cataplexy, Emotional disorder, Hallucination, Muscular weakness
Clinical narrative: Narcolepsy with Cataplexy; cannot work and is on disability; Narcolepsy with Cataplexy; weakness in her legs; loses bodily control and drops to the floor with her eyes rolled back into her head; loses bodily control and drops to the floor with her eyes rolled back into her head; had changes in her body after receiving the vaccine; Initial information received on 13-Jan-2022 regarding an unsolicited valid serious case received from a consumer/non-hcp.  This case involves female patient of unknown age who had narcolepsy with cataplexy, cannot work and is on disability, narcolepsy with cataplexy, weakness in her legs, loses bodily control and drops to the floor with her eyes rolled back into her head, loses bodily control and drops to the floor with her eyes rolled back into her head and had changes in her body after receiving the vaccine while receiving vaccine INFLUENZA VACCINE (QUADRIVALENT).  The patient's past medical history, medical treatment(s), vaccination(s) and family history were not provided.   On 30-Nov-2010, the patient received an unknown dose of suspect INFLUENZA VACCINE (QUADRIVALENT) produced by unknown manufacturer (strength, formulation, frequency, route, administration site was unknown, lot UH214AB and expiry date was unknown) for prophylactic vaccination.  It was reported by patient that adverse reactions that have existed for 11 years that her world-renowned sleep physician, states it stems from that vaccine. Patient stated that she had changes in her body after receiving the vaccine (unevaluable event), she had experienced weakness in her legs (Muscular weakness) and had been diagnosed with Narcolepsy with Cataplexy (Narcolepsy, cataplexy) (onset and latency: unknown). Reportedly stated that she loses bodily control (Balance disorder) and drops to the floor with her eyes rolled back into her head (eye movement disorder) (onset and latency: unknown). Patient had a letter from her doctor describing the events, she states she cannot work and was on disability (impaired work ability) (onset and latency: unknown). Patient wonders what the company would do to compensate her for her struggles  Action taken: not applicable.  Corrective treatment: not reported  Outcome: unknown for unevaluable event and not recovered for other events  Seriousness criteria: Medically significant for event narcolepsy, cataplexy and disability for impaired work ability; Sender's Comments: Sanofi company comment dated 13-Jan-2022: This case involves female patient of unknown age who had Narcolepsy, Impaired work ability and Cataplexy after receiving INFLUENZA VACCINE (QUADRIVALENT). (Manufacturer unknown). The time to onset is not reported with the role of the vaccine. The clinical course of the event was not provided. Furthermore, information regarding condition at the time of vaccination, role of medical history, concomitants, lab data excluding other predisposing etiologies would be needed for complete assessment of the case. Based upon the reported information, the role of an individual vaccine cannot be assessed.