Age: 60.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Blister, Blood test, Chest X-ray, Erythema, Herpes zoster
Clinical narrative: Diagnosed her with shingles; Two blisters on her left hand within 1/2 inch of each other / blisters on her neck; Blisters got more red / redness on her neck; the area was spreading approximately 2 inches and swelling / worsening swelling; Area was spreading approximately 2 inches with purple and black skin / black color continued to worsen / finger was turning black and then purple; Tiny bumps on her thumb of her left hand / finger with swelling; This case was reported by a consumer via call center representative and described the occurrence of shingles in a 60-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Flu vaccine (Received on an unknown date with no issues). Concomitant products included antibiotics nos (Antibiotics Therapy (Unknown)) and antifungals nos (Antifungal).   On 3rd December 2019, the patient received the 1st dose of Shingrix (injection). On 24th December 2019, 21 days after receiving Shingrix, the patient experienced shingles, swollen thumb, blister, erythema, swelling and skin discoloration. The action taken with Shingrix was unknown. On an unknown date, the outcome of the shingles, blister, erythema, swelling and skin discoloration were unknown and the outcome of the swollen thumb was recovered/resolved.   It was unknown if the reporter considered the shingles, swollen thumb, blister, erythema, swelling and skin discoloration to be related to Shingrix.  Additional case details were reported as follows: The patient experienced tiny bumps on her thumb of her left hand and two blisters on her left hand within 1/2 inch of each other. Throughout the day, the blisters got more red the area was spreading approximately 2 inches and swelling with purple and black skin.  On 25th December 2019, patient went to the ER but was not admitted and the black color continued to worsen with worsening swelling.  The patient received strong antibiotic and the condition started to go away. Two weeks later, the same thing happened on her right ring finger and she experienced redness and blisters on her neck. Her finger was turning black and then purple with swelling and she had to have her ring cut off.  The patient was treated with an anti fungal medication and later diagnosed her with shingles,  later switched to a broad spectrum antibiotic within 24 hours. Everything resolved by that Friday or Saturday and she had no evidence of shingles on her neck.  Her fingers took a while longer to resolved and the swelling took about 2 weeks to resolve.  Her initial side effects started 2 weeks after getting the Shingrix vaccine and then 2 weeks later she had shingles. She was told that the antibiotics had no impact on the resolution of her side effects.  When they were trying to diagnose her she saw four doctors including an endocrinologist  They drew 7 vials of blood to rule out other conditions before determining that she had shingles.  The symptoms on the patient's left hand started on 24th December 2019 and the symptoms on her right hand occurred on 10th January 2020. Reporter consented to follow up.