Age: 24.0
Sex: F
Vaccine: FLUC4
Symptoms: Generalised tonic-clonic seizure, Headache, Heart rate increased, Laboratory test abnormal, Life support
Clinical narrative: She got her vaccine, she was excessively tired.  She attributed it to being her last semester of nursing school, graduation coming up, etc.  She was working and going to school at the same time.  She was having headaches, and she was taking more than her normal amounts of Motrin and Tylenol.  She was on a trip in November, around 11/5/21 and did not go shopping with her friends and went to the car to lie down.  The next time she contacted her mother was on 11/20/21 before she flew home, and felt that she felt that she had a bladder infection.  She then called again around 11:00 AM before her flight and had diarrhea and attributed that to drinking cranberry juice on an empty stomach to relieve her bladder issues.  She made home that evening, and on 11/21/21 she made it through the day, had some Azos for bladder spasms, drinking fluids and resting until she get to the doctor on Monday.  She went to the doctor on Monday 11/22/21, and was given Nitrofurantoin, and felt that she had a residual sinus infection and bladder infection.  She only took one of those throughout that week as she was not feeling well.  She was cultured and nothing grew. She came home on 11/22/21 with severe headache, migraine and had to be escorted into the house, mother  her into a bath and gave her some Aleve PM for that and she went to bed.   She then broke out into a rash faintly on 11/23/21 on her forearms.  She did not take anything for this and then stopped the antibiotics thinking that was the reason for the reaction.   On Wednesday/Thursday she had the headache and continued to treat that, and then managed that with Motrin/Tylenol as needed for the pain (not a medicine taking person).  On Friday in the early evening that she still was not feeling well, and started complaining about her neck hurting.  Mother's thoughts went to meningitis, which she had been thinking as well, and did testing for that (in nursing school), and decided that was not the cause.  On Saturday 11/26/21 in the afternoon they were working on her graduation announcements and party invitations, and mother noticed her face was very flushed.  She took her temperature which was 100.2.    Mother told her to clear her schedule for Sunday.  On 11/28/21 they went and by that time the rash was more pronounced on her arms, back and on her trunk.    At that point it was not itchy, nothing that bad, and later that afternoon it became extremely itching, and mother gave her 5 Benadryl between 1:00 and 10:00 PM, and that's when she called her PCP.  The daughter sent pictures of her rash to her friends who were in the medical field with her and asked if they knew what it was.  They felt that it was 5th disease, and nothing to do for it but Motrin, Tylenol and Benadryl and went home and slept most of the day.    Her boyfriend scratched her back all afternoon and early evening.  Mother put Calamine lotion on her and nothing was helping the itching.  She made a phone call to her PCP, and he said that he was not sure about the diagnosis and wanted her to be seen the next morning at 8:00 AM.    Her mother found her at 3:00 AM vomiting and at 7:00 AM her father told the mother that she was still vomiting and mother went to assess her then.  At that time she was well enough to tell her that she had picked out the wrong clothes to wear to the hospital.  They were probably on the road about 7:30 and she was very unsteady according to the father, dragging her feet, very dizzy.  Mother took her to hospital.  They got to the hospital and mother got a wheelchair to the car and the daughter said "momma, I can't do it".  Mother went and got an orderly who helped to get in from the car to the wheelchair.  They took her back rather quickly to triage within 5 minutes.  They asked her her name and she did not respond, just stared blankly at everybody.  Then they went back out to the waiting room as they were getting a room ready for her, and she was continuously vomiting.  They got into a room and the medical assistant was getting ready to start an IV, and mother told him that she was pretty dehydrated and would be hard to find a vein, and daughter was very fidgity and stated "I don't trust him".  Then the nurse came in and he ended up doing the IV.  The PA came in that's when she was doing the assessment of the daughter and when she pushed down on her stomach she was coming off the table in pain. Mother believes she yelped and after the IV's were started they did the first blood draw.  The nurses came in and out, not a lot of activity during that time, 11:30 PM, waiting for blood work results ,doctors orders or so.  Around 11:30 mother yelled for help as daughter had a tonic clonic grand mal seizure.  They came in and immediately gave her antiseizure medicine (in medical report), which helped to a point.  They sent her back for a CAT scan of her head.  When she came back to the room mother states that she was reaching to the sky with her arms, feeling she may have been coming out of the seizure.  Her father had arrived at that time.  They asked them to leave as they needed a sterile environment to perform a spinal tap.  When they came back into the room they said they  had to tap her twice as they were not getting a lot of spinal fluid.  They sat with her for a while, did a teleconference call with the neurologist at the main hospital, and while they were telling her everything that had transpired during the week and watched her during that call and was pretty much in a coma.  She was breathing on her own, but not responding.  They came in around 4:00 PM and they were going to push medicines (mother did not know what), and did not push it and her heart rate jumped to 208 and alarms went off in the room and nurses station, and mother "lost it".  They came in the crash cart, which mother could not watch, went out into the hall.  They said that she never lost heart beat, and was shocking her to get her back into normal rhythm, which it did go back to normal.  At that time they decided to take her to another hospital by helicopter.    They flew her there, mom packed bags and her family has an EMT went to the hospital and answered the questions for the family.  When parents got to the hospital they were met by three neurologist and the Chaplin.  One of the neurologist told them if they were praying people to start praying.  They sent her for 3 CAT scan's and they took her back also for an in-depth MRI with and without contrast.  They brought her back to the room, she was still unconscious/coma.  Her were slit, a little bit opened, and the priest returned with them, read her the last rites, closed her eyes and did not regain.  The CAT scan did not show anything, and the neurologist noticed that she had something at the base and he diagnosed her with Chiari malformation.   Family came to the hospital, and she was ventilated, was breathing, and there was no brain swelling.   The nurses told the mother that she was one of them (nursing student), they told her to go home and get rest, and she did not want to do so.  She went home and then got a phone call at 3:00 AM on 11/30/21 which was the head charge nurse and she said that she did not want her to be alone and that one of the surgeons came in ready to do any surgery for her, and he did a pretty in-depth test on her and there was no response mother "lost it".  They came in the crash cart, which mother could not watch, went out into the hall.  They said that she never lost heart beat, and was shocking her to get her back into normal rhythm, which it did go back to normal.  At that time they decided to take her to other hospital by helicopter.    They flew her there, mom packed bags and her family has an EMT went to the hospital and answered the questions for the family.  When parents got to the hospital they were met by three neurologist and the Chaplin.  One of the neurologist told them if they were praying people to start praying.  They sent her for 3 CAT scan's and they took her back also for an in-depth MRI with and without contrast.  They brought her back to the room, she was still unconscious/coma.  Her were slit, a little bit opened, and the priest returned with them, read her the last rites, closed her eyes and did not regain.  The CAT scan did not show anything, and the neurologist noticed that she had something at the base and he diagnosed her with Chiari malformation.   Family came to the hospital, and she was ventilated, was breathing, and there was no brain swelling.   The nurses told the mother that she was one of them (nursing student), they told her to go home and get rest, and she did not want to do so.  She went home and then got a phone call at 3:00 AM on 11/30/21 which was the head charge nurse and she said that she did not want her to be alone and that one of the surgeons came in ready to do any surgery for her, and he did a pretty in-depth test on her and there was no response.  That doctor had done an indepth neurologic work up on her and informed them that she was brain dead with no brain activity around 12/1/21 at noon.  She was then kept on life support as she was an organ donor to preserve her organs and was taken to the organ donoting hospital after they pronounced her the following day.  Mother did some research and have friends who are doctors and researched transverse myelitis and mother still kept researched Guillain Barre with her symptoms. Info and then she started researching thrombocytopenia.  The key symptoms was the rash, on her legs, thighs and her nephew (EMT) noticed that right off as well.    The autopsy came back as intraparenchymal hemorrhage, peripheral and had hemorrhaged C1-C4 spinal cord.  The coroner listed her death as complications of Chiari malformation, which was felt to be very minimal, and by the time the body came back it was 8 mm, which did not show up on MRI imaging.     She was a very active person, very healthy.    Doctor/lawyer team believe it was the flu vaccine and possibly interaction with the Pfizer vaccine.