Age: 65.0
Sex: F
Vaccine: FLU4
Symptoms: Pain in extremity, Tinnitus
Clinical narrative: nerve pain- a migrating pain that went everywhere; she had an MRI last week, which "spiked" her tinnitus; swollen left ankle; overstimulated my immune system; began to limp; she also developed inflammation of her veins, in her hands and feet; sore (left) arm, pain in her left hand/ wrist joint, in-between the web of her left hand (she describes as between the bones on the back of her hand) that night, the pain spread to her right hand; on-going myalgia of her neck, shoulders and back; poly-arthralgia- all over specifically mentioning her ankles, feet and toes; headaches; sore (left) arm, pain in her left hand/ wrist joint, in-between the web of her left hand (she describes as between the bones on the back of her hand) that night, the pain spread to her right hand; Initial information received on 09-Feb-2021 regarding an unsolicited valid non-serious case from a consumer/non-health care professional.  This case involves a 65 years old female patient who experienced nerve pain- a migrating pain that went everywhere (neuralgia), had an MRI last week, which "spiked" her tinnitus (tinnitus), swollen left ankle (joint swelling), overstimulated immune system (immune system disorder), began to limp (gait disturbance), she also developed inflammation of her veins, in her hands and feet (inflammation), sore (left) arm, pain in her left hand/ wrist joint, in-between the web of her left hand (she describes as between the bones on the back of her hand) that night, the pain spread to her right hand (pain in extremity) (vaccination site reaction), on-going myalgia of her neck, shoulders and back (myalgia), poly-arthralgia- all over specifically mentioning her ankles, feet and toes (arthralgia),and headaches (headache) , after receiving INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE [FLUZONE HIGH-DOSE QUADRIVALENT].  Patient had never received a flu vaccine before and states that she does not remember ever receiving any vaccines unless it was when she was a child and does not have a memory of it.  Past medical treatment(s), vaccination(s), concomitant medication(s) and family history were not provided.  On 15-Oct-2020, the patient received a 0.7 ml dose of suspect INFLUENZA QUADRIVAL A-B HIGH DOSE HV VACCINE (lot UJ469AB and expiration date not reported) via intramuscular route in the left arm for prophylactic vaccination given by her primary care provider.  On an unknown date, the patient reported that when she "first got it" she quickly noticed that in addition to a sore (left) arm, she developed pain in her left hand/ wrist joint, and in-between the web of her left hand (she describes as between the bones on the back of her hand). That night, the pain spread to her right hand (vaccination site reaction) (pain in extremity).  The bilateral hand pain became so severe over the next few days, that she couldn't lift her iPhone.  On an unknown date, the patient complained of on-going myalgia of her neck, shoulders and back (myalgia). She stated that her left arm was sore down to elbow area, and both shoulders still hurt. The pain has decreased since initial onset but was still quite painful. She described "poly-arthralgia- all over"; specifically mentioning her ankles, feet and toes (arthralgia).  She reported nerve pain- a migrating pain that went everywhere (neuralgia). She states that she cannot use her hands properly even now.  She mentions hand and wrist braces being used, those may be discontinued at this time, she was not specific.  On an unknown date, also reported that one day she was in her garage, just walking around, and her foot started to hurt badly. She began to limp (gait disturbance), and "had to go to bed" for the rest of the day.  Also reported that two weeks ago, she sprained her knee, trying to rise from a sitting to standing position. Caller emphasized that she has always been a healthy, active person, who does not take medications, including over-the-counter analgesics.  Reporter reported that she had seen two rheumatologists since the onset of these symptoms- she had an MRI (Magnetic resonance imaging) last week, which "spiked" her tinnitus (tinnitus).  She further reported, a swollen left ankle (joint swelling) and headaches (headache).  Patient stated that "the scariest part" was that she also developed inflammation of her veins, in her hands and feet (inflammation).  Her various HCPs (health care professional) had told her that the vaccine "overstimulated my immune system and made it attack itself" (immune system disorder).  All the reported events were non serious and the latencies were unknown for all the events.  Patient was prescribed Prednisone, but "couldn't take it" because it increased her heart rate. She is now very depressed and feels that the vaccine has so debilitated her that it "has maimed her" She states that it should be taken off the market. She also reported extreme fear of taking the COVID 19 (coronavirus disease) m-RNA (Messenger Ribonucleic Acid) vaccines, because she had been reading about all the people who have died from that vaccine.  And now the patent needs a list of all the ingredients in FLUZONE HIGH-DOSE QUADRIVALENT as She states that she suffered a serious adverse event, which she has already reported.  Other relevant laboratory tests were not reported.  At the time of reporting, the outcomes were unknown for all the events.