Age: 74.0
Sex: M
Vaccine: VARZOS
Symptoms: Arthralgia, Immediate post-injection reaction, Injected limb mobility decreased, Mood altered, Muscular weakness
Clinical narrative: Decreased mobility of the injected arm; arm and hand pulsating which wakes him up 4-5 times per night (making him grouchy); Loss of strength of the injected arm; making him grouchy; hand pain; shoulder pain; This non-serious case was reported by a consumer via call center representative and described the occurrence of pain in hand in a 74-year-old male patient who received Herpes zoster (Shingrix) (batch number Z3H93, expiry date 07-JUL-2024) for prophylaxis.   On 27-APR-2023, the patient received the 1st dose of Shingrix (unknown arm). On 27-APR-2023, immediately after receiving Shingrix, the patient experienced pain in hand (Verbatim: hand pain) and shoulder pain (Verbatim: shoulder pain). On an unknown date, the patient experienced injected limb mobility decreased (Verbatim: Decreased mobility of the injected arm), sleep disturbance (Verbatim: arm and hand pulsating which wakes him up 4-5 times per night (making him grouchy)), weakness of arms (Verbatim: Loss of strength of the injected arm) and bad mood (Verbatim: making him grouchy).  The patient was treated with steroids nos (Steroid (Not Specified)). The outcome of the pain in hand, shoulder pain, injected limb mobility decreased, sleep disturbance, weakness of arms and bad mood were not resolved.   The reporter considered the pain in hand, shoulder pain, injected limb mobility decreased, sleep disturbance, weakness of arms and bad mood to be related to Shingrix.     The company considered the pain in hand, shoulder pain, injected limb mobility decreased, sleep disturbance, weakness of arms and bad mood to be related to Shingrix.   Additional Information: GSK Receipt date: 05-SEP-2023 and 07-SEP-2023 The reporter was the wife of patient.  The patient received the Shingrix dose at a grocery store pharmacy on 27-April-2023 and had immediate pain from the shoulder to his hand.  He came home and he was sore and we thought it would go away but had not gone away. He was in terrible pain. He was picking up steroids or something to calm his pain.  The patient went to see the doctor about a week after the injection and the doctor blew it off as arthritis but it is not arthritis. The reporter indicated that her husband had an appointment today with the doctor and he prescribed steroids and he was going to see the doctor again at the end of next week. They are going to set up a neuro exam' for him.  The reporter mentioned to her that the package insert mentions in the post-marketing area Decreased mobility of the injected arm which may persist for 1 or more weeks. She indicated that her husband had decreased mobility of the injected arm and that his arm had no strength. (Prior to the Shingrix shot he was a very strong 73 year old).  This was also affecting the shoulder and hand. She said he lost 60 to 70 percent of his strength in his arm and hand and it pulsates and keeps him up. He wakes up 4 or 5 times per night making him a grouch'. The reporter consented to follow up. This case was linked with case US2023121051 with same reporter.; Sender's Comments:  US-GSK-US2023121051:Same reporter, different patient