Age: 26.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Fatigue, Headache, Pyrexia
Clinical narrative: headaches; feeling tired; low grade fever of 100; a lot of chest pain; cramp; tightness; large migratory hives/I develop hives/raised whelps/anything that applies pressure I develop whelps; rash; itching; dermatographism anything that applies pressure/if a tank top touches and applies pressure; This spontaneous case was reported by a patient and describes the occurrence of HEADACHE (headaches), FATIGUE (feeling tired), PYREXIA (low grade fever of 100), URTICARIA (large migratory hives/I develop hives/raised whelps/anything that applies pressure I develop whelps) and RASH (rash) in a 26-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   In February 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 31-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 21-May-2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 31-May-2022, the patient experienced URTICARIA (large migratory hives/I develop hives/raised whelps/anything that applies pressure I develop whelps), RASH (rash), PRURITUS (itching) and MECHANICAL URTICARIA (dermatographism anything that applies pressure/if a tank top touches and applies pressure). On 16-Jun-2022, the patient experienced CHEST PAIN (a lot of chest pain), MUSCLE SPASMS (cramp) and CHEST DISCOMFORT (tightness). On an unknown date, the patient experienced HEADACHE (headaches), FATIGUE (feeling tired) and PYREXIA (low grade fever of 100). The patient was treated with SALBUTAMOL SULFATE (ALBUTEROL [SALBUTAMOL SULFATE]) at an unspecified dose and frequency; PREDNISONE at an unspecified dose and frequency and LEVOCETIRIZINE DIHYDROCHLORIDE (XYZAL) at an unspecified dose and frequency. At the time of the report, HEADACHE (headaches), FATIGUE (feeling tired) and PYREXIA (low grade fever of 100) had resolved and URTICARIA (large migratory hives/I develop hives/raised whelps/anything that applies pressure I develop whelps), RASH (rash), PRURITUS (itching), MECHANICAL URTICARIA (dermatographism anything that applies pressure/if a tank top touches and applies pressure), CHEST PAIN (a lot of chest pain), MUSCLE SPASMS (cramp) and CHEST DISCOMFORT (tightness) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Body temperature: 100 (High) low grade fever of 100. On an unknown date, Electrocardiogram: results not reported Results not reported. On an unknown date, X-ray: results not reported Results not reported.         No concomitant medication information provided. The patient had not taken any other vaccines within 1 month prior to Moderna COVID-19 vaccine.  The patient had no other medical history except COVID-19 diagnosed on 22-Dec-2021 (no hospitalization). Patient had not experienced symptoms like this before receiving the Moderna COVID-19 vaccine. Patient had no history of Myocarditis/pericarditis. Patient stated that she was not referred to cardiologist because her tests were normal.  The events headaches, feeling tired, and low grade fever lasted for 24hours. The patient visited allergist after 2 days experiencing hives, who mentioned that the events could be an effect from the booster. It was reported that the symptoms occurred 4 times a day and lasted for 20 minutes. The clinical outcome included normal findings.  The patient also used ice packs which seemed to hep for a couple of weeks, however albuterol inhaler showed no difference.   This case was linked to MOD-2022-592989 (Patient Link).