Age: 67.0
Sex: M
Vaccine: VARZOS, VARZOS, VARZOS
Symptoms: Herpes zoster, Intercepted product prescribing error, Vaccination failure, Vaccine breakthrough infection
Clinical narrative: has not received the shot because the pharmacies refused to give it; Suspected vaccination failure; developed shingles; This case was reported by a consumer via call center representative and described the occurrence of vaccination failure in a 67-year-old male patient who received Herpes zoster (Shingrix) (batch number LH7ED, expiry date unknown) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) (batch number LH7ED, expiry date unknown) for prophylaxis and Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included prior immunization with zoster (Zostavax) in 2008 (received in 2008), Moderna Covid, pneumococcal, TB and influenza vaccine.   On 16th November 2020, the patient received the 2nd dose of Shingrix (intramuscular) .5 ml. On 21st August 2020, the patient received the 1st dose of Shingrix (intramuscular) .5 ml. On 16th November 2020, the dose was .5 ml (.5 ml daily). On an unknown date, the patient received the 3rd dose of Shingrix. In January 2022, between 1 and 2 years after receiving Shingrix and Shingrix and not applicable after receiving Shingrix, the patient experienced vaccination failure (serious criteria GSK medically significant) and shingles. On an unknown date, the patient experienced intercepted drug prescribing error. On an unknown date, the outcome of the vaccination failure and intercepted drug prescribing error were unknown and the outcome of the shingles was recovered/resolved.   It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingrix and Shingrix.     Additional Information: GSK Receipt Date: 31-Mar-2022 Reporter's Comments:  The patient self-reported the case. After receiving Shingrix, the patient developed a (breakthrough) case of shingles in January 2022 which lasted 4-5 weeks then resolved. The patient's doctor prescribed him to get a Shingrix booster (3rd dose of Shingrix). The patient had the prescription but had not yet received the shot because he went to 2 pharmacies and they refused to give it. The reporter stated that, some of the other vaccinations listed might have been administered after Shingrix and before the shingles outbreak but the patient did not provide dates. The patient was sitting at his computer looking at his medical records through his portal and was trying to find the date of when he had Shingrix shot 1 and Shingrix shot 2, as he was looking he was reading aloud some of the other things he was seeing, he was just reading out loud what he saw listed under his immunization profile but was not familiar with what he was seeing. Because he was searching for Shingrix he did not indicate the dates the other shots were given, other than Zoster The patient saw influenza listed many times (probably yearly), he also saw Moderna-Covid, and pneumococcal. The patient saw TB and said whatever that was it but it might be Td (Tetanus-diphtheria) although it was not clear. The patient then he found zoster and then said 2008 was the original shot. Then he later found Shingirx and found the exact dates and lot numbers. The reporter did not consent to follow-up and did not want to provide his MD contact information. Additional Supportive Information: This case described the occurrence of suspected vaccination failure. This case was considered as suspected vaccination failure as details regarding laboratory test confirming shingles were unknown at the time of reporting. The patient was prescribed the 3rd dose of Shingrix which was not administered yet, which led to intercepted drug prescribing error.