Age: 82.0
Sex: F
Vaccine: COVID19
Symptoms: Anaphylactic reaction
Clinical narrative: anaphylactic reaction; This spontaneous case was reported by a consumer and describes the occurrence of ANAPHYLACTIC REACTION (anaphylactic reaction) in an 82-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 038A21A) for COVID-19 prophylaxis.     Question:Describe relevant medical history/conditions, allergy, concomitant diseases and risk factor.Answer:Allergies: Bees, pollen, ragweed, Levaquin Osteoporosis- stable since she uses weights.  Concurrent medical conditions included Allergy (Bees, Levaquin), Pollen allergy, Ragweed allergy and Osteoporosis (stable since she uses weights).    On 21-Mar-2021, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced ANAPHYLACTIC REACTION (anaphylactic reaction) (seriousness criterion medically significant). The patient was treated with PREDNISONE at an unspecified dose and frequency. At the time of the report, ANAPHYLACTIC REACTION (anaphylactic reaction) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant medication not reported.  She received all of the Moderna COVID-19 vaccinations. She had a severe bee allergy, so she stayed away from Pfizer. She sat on a bee when she was 32 and had an anaphylactic reaction. She almost died. She has never been bit since. When she had the first shot she had a rash on her left arm from her elbow to all the way up her left shoulder. Her arm was red and itchy from her elbow to her left shoulder. She also described it as an itchy big thing. It stayed red for about a week. Her doctor told her to take prednisone and Benadryl before taking the next shots. After she took the prednisone she did not have any reaction aside from redness. She was 83 and healthy. When she got the previous shots she was at a hospital site where they would watch her due to her reaction with her arm on the first one. She stated she would sit for 30 minutes, and she would be fine. She was going to her doctor for prednisone. She had pictures of her first reaction. She stated her friends had reactions such as shivering and fever but then confirmed they received Pfizer not Moderna. Previous Moderna COVID-19. Second vaccinations on 20-Apr-2021, batch number: 039B21A. Third vaccination on 23-Nov-2021, batch number: 014F21A. Fourth vaccination on 03-May-2022, batch number: 045L21A. Fifth vaccination on 31-Oct-2022, batch number: 050022A.  Company Comment This spontaneous case concerns a 82-years-old-female patient, with medical history of allergies to Bees, pollen, ragweed, and Osteoporosis who experienced the seriousness criterion medically significant expected event of anaphylactic reaction unknown days after a dose of mRNA-1273 vaccine.  Concomitant medication details  were not reported. The medical history of several allergies is a contributor fir the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.