Age: 52.0
Sex: F
Vaccine: VARZOS
Symptoms: Stomatitis, Swollen tongue, Tongue eruption
Clinical narrative: only eating and drinking to survive due to excruciating pain; they noticed pimples; little red dots; pimples/little red dots, like spider bites on tongue /rash ran across the down to the base of the tongue; pimples/little red dots like spider bites on the roof of the mouth. Is bright pink with a yellowpuffy line; base of tongue still have some inflammation/ inflammation that looked like spider bites; base of the tongue was painful/ feels like an open sore; base of the tongue was swollen; "knife -like" pain in the head; unable to sleep at night, being awakened by the pain; area on roof of mouth is bright pink with a yellow, puffy line down the middle; Shingles rash; Restlessness; sore and inflammationon/irritation on the roof of the mouth/ mouth irritation; large blood blister; blood blister immediately ruptured; painful area on the mouth. Pain was excruciating when they ate or drank; This case was reported by a consumer via call center representative and described the occurrence of shingles in a 52-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included shingles (outbreak of shingles in the mouth over a decade ago, but with less severe symptoms).   On 2nd October 2021, the patient received the 1st dose of Shingrix. On 15th October 2021, 13 days after receiving Shingrix, the patient experienced shingles, restlessness, sores roof of mouth, blood blister, blister rupture, oral pain and oral mucosal discoloration. On 16th October 2021, the patient experienced pimples, red rash, rash tongue, rash mouth, tongue inflammation, tongue pain, swollen tongue, headache and sleeplessness. On 17th October 2021, the patient experienced swallowing difficult. The patient was treated with lidocaine (Lidocaine Mouthwash) and sodium chloride (Salt Water). On 25th October 2021, the outcome of the swallowing difficult was recovered/resolved. On an unknown date, the outcome of the shingles, restlessness, sores roof of mouth, blood blister, blister rupture, oral pain, pimples, red rash, rash tongue, rash mouth, tongue inflammation, tongue pain, swollen tongue, headache, sleeplessness and oral mucosal discoloration were not recovered/not resolved.   It was unknown if the reporter considered the shingles, restlessness, sores roof of mouth, blood blister, blister rupture, oral pain, pimples, red rash, rash tongue, rash mouth, tongue inflammation, tongue pain, swollen tongue, headache, sleeplessness, swallowing difficult and oral mucosal discoloration to be related to Shingrix.  Additional details were provided as follows: The case is self-reported. The patient received a dose of Shingrix and symptoms began on 15th October 2021, around noon. The reporter stated that, she was eating and felt something like a sore on the roof of the right side of the mouth, viewing the area and seeing a large, blood blister that immediately ruptured.  After the blood blister erupted, the area become more and more painful. In the next day or so, the patient noticed pimples/little red dots around the initial area of inflammation that looked like spider bites and were in a line.  The patient also reported that, the rash ran across the roof of the mouth and down to the base of the tongue. The base of the tongue was painful and swollen, experienced "knife -like" pain in the head and often being unable to sleep at night, due to the pain.  The patient was only eating to survive from 17th October 2021 until 24th October 2021, due to excruciating pain whenever she ate or drank anything. On 18th October 2021, the patient visited emergency room after being awakened by the pain and was provided with lidocaine mouthwash. The patient was also using salt water to try and manage the pain.  The reporter stated that, as of 25th October 2021, pain was manageable and she was able to eat without excruciating pain.  The roof of the mouth and base of tongue still had some inflammation and the area on roof of mouth was bright pink with a yellow, puffy line down the middle and still feels like an open sore. The roof of the mouth still had some inflammation/irritation. The reporter consented to follow up.