Sex: F
Vaccine: COVID19, UNK
Symptoms: Blood test, Diarrhoea, Faeces discoloured, Fatigue, Investigation
Clinical narrative: Diarrhea; Gray stools; Tiredness/feel moderately tired; Right hand pain stiffness in joints and fingers; Right hand pain stiffness in joints and fingers; Right hand pain stiffness in joints and fingers; Her right hand continues to feel stiff; Not sure if this has helped. She still has significant pain; This is a spontaneous report from a Pfizer-sponsored program, received from a non-contactable consumer (patient) and subsequently from a contactable nurse and a contactable physician.  A 62-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE), dose 1 via an unspecified route of administration on an unspecified date (Batch/Lot number was not reported) as SINGLE DOSE for covid-19 immunisation; tofacitinib citrate (XELJANZ XR), oral from Feb2021 (Batch/Lot Number: DL0309) to an unspecified date, at 11 mg, daily, oral from an unspecified date (Batch/Lot Number: DD9555) to an unspecified date, at 11 mg, via an unspecified route of administration from an unspecified date (Batch/Lot number was not reported) and ongoing, at 11 mg, daily for Erosive inflammatory arthritis, psoriatic arthropathy, of the hands, feet, as pine and spine.  .  Medical history included : Diagnosis: Arthropathic psoriasis, unspecified. The patient's concomitant medications were not reported.  . On unspecified date the patient experienced right hand pain stiffness in joints and fingers, tiredness, one or two missed doses due to diarrhea and gray stools. Patient stated that she started probably around 07Feb2021. Patient stated she had not refilled because she thought it was on auto refill. Patient stated having had diarrhea after starting XELJANZ and missed one or two days due to symptoms, and gray color stool. Patient also stated being tired moderately. Patient also stated that she had still pain and used MOBIC for right hand fingers and joints. Patient's ARMS (Adherence to Refills and Medications Scale) 7 high risk, low adherence score (8+), discussed importance of taking medication and setting refills on time, she denied missed doses. Patient wanted to know about the COVID vaccine, she was advised patient to speak to medical doctor (reported as MDO). Patient verbalized understanding, she agreed to adherence calls, and she had no questions. Nurse advised patient to contact pharmacy for any questions and refills.Subsequently the Patient indicated she continues to feel moderately tired but is not sure if its because she had the Covid-19 vaccine. Symptoms of diarrhea and gray stool that were previously reported on 08Mar2021 have resolved. Additionally, she confirmed she missed one dose of Xeljanz on the day she received her COVID-19 vaccine. Patient confirmed Her right hand continues to feel stiff, she has three days of Xeljanz on hand.The patient Continued on Xeljanz. Not sure if this has helped. She still has significant pain. Treatment received for Right hand pain stiffness in joints and fingers.Lab data included also blood work :unknown results on unknown date.The patient recovered from Diarrhea and Gray stools , not recovered from Tiredness/feel moderately tired.The outcome of the other events was unknown.  Follow-up (07Apr2021,08Apr2021 and 09Apr2021): This is a follow-up report combining information from duplicate reports 2021389939 and 2021269483. The current and all subsequent information will be reported under manufacturer report number 2021269483.New information recevied from a Pfizer Sponsored Program and another   Pfizer Sponsored Program from a contactable nurse and non-contactable consumer rand a contactable physician includes: Adding of suspect drug (bnt162b2) , suspect drug details, clinical course, new adverse reaction, treatment , outcome and additonal  lab data.   No follow-up attempts are possible; information about lot/batch number cannot be obtained.