Sex: F
Vaccine: COVID19, VARZOS
Symptoms: Abdominal discomfort, Computerised tomogram, Fatigue, Feeling abnormal, Frequent bowel movements
Clinical narrative: She is also experiencing neuropathy and stiffness in her hands; She is also experiencing neuropathy and stiffness in her hands; like she is "walking on bones"; bowels are not as predictable as they used to be for her, and she has multiple movements a day; bowels are not as predictable as they used to be for her, and she has multiple movements a day and does not feel that she is "emptying out"; she was so tired for 3 days; This is a spontaneous report received from a contactable reporter(s) (Other HCP) from medical information team. The reporter is the patient.  A 62-year-old female patient received BNT162b2 (BNT162B2), on 04Aug2021 as dose 2, single (Lot number: FA7485) for covid-19 immunisation; varicella zoster vaccine rge (cho) (SHINGRIX), on 04Aug2021 as unk unk, single (Batch/Lot number: unknown) for immunisation. The patient's relevant medical history included: "anxiety" (unspecified if ongoing); "depression" (unspecified if ongoing); "allergic reaction to "everything"" (unspecified if ongoing). The patient's family history included: "heart disease" (unspecified if ongoing). Concomitant medication(s) included: FAMOTIDINE taken for anxiety; SEROQUEL taken for depression. Vaccination history included: BNT162b2 (Dose 1 (Lot EW0196), left arm), administration date: 14Jul2021, for COVID-19 immunization, reaction(s): "myocarditis"; BNT162b2 (Dose 1 (Lot EW0196), left arm), administration date: 14Jul2021, for COVID-19 Immunization, reaction(s): "1P36 deletion syndrome"; BNT162b2 (Dose 1 (Lot EW0196), left arm), administration date: 14Jul2021, for Covid-19 Immunization, reaction(s): "sore arm". The following information was reported: NEUROPATHY PERIPHERAL (medically significant), MUSCULOSKELETAL STIFFNESS (non-serious), outcome "unknown" and all described as "She is also experiencing neuropathy and stiffness in her hands"; FATIGUE (non-serious), outcome "unknown", described as "she was so tired for 3 days"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "like she is "walking on bones""; FREQUENT BOWEL MOVEMENTS (non-serious), outcome "unknown", described as "bowels are not as predictable as they used to be for her, and she has multiple movements a day"; ABDOMINAL DISCOMFORT (non-serious), outcome "unknown", described as "bowels are not as predictable as they used to be for her, and she has multiple movements a day and does not feel that she is "emptying out"". The event "she was so tired for 3 days" required emergency room visit. The patient underwent the following laboratory tests and procedures: Computerised tomogram: Unknown result. The patient has had 2 doses. The first was on 14Jul2021 (Lot EW0196), and the second was on 04Aug2021 (Lot FA7485). She states that a nurse told her over the weekend that she should have gotten Moderna because it has no side effects. She was told that Pfizer had side effects of myocarditis, then mentioned that she has a family history of heart disease, but that she never had issues with heart disease or blood pressure. It was unclear if she was implying that she is experiencing those issues. She is also asking if 1P36 deletion syndrome is related to the vaccine, as well as neuropathy and bowel issues.  She states that after the first shot, all she had was a sore arm, then states that she got it in her left arm, where there was also a nicotine patch. After her second dose, where she also was given a shingles vaccine, she states "holy geez", and reports that she was so tired for 3 days, she was taken by ambulance to the emergency room (ER), where they did a computerized tomogram (CT) scan. She is also experiencing neuropathy and stiffness in her hands, and feels it when she is walking, like she is "walking on bones". Her bowels are not as predictable as they used to be for her, and she has multiple movements a day and does not feel that she is "emptying out", but she believes this may be attributed to her psych meds. Caller reports that she takes Famotidine and Seroquel, has anxiety and depression, and that she had an allergic reaction to "everything" as a child. It was unclear if she was referring to medications, as the example she gave was about poison ivy. The event "she was so tired for 3 days" required emergency room visit. The patient underwent the following laboratory tests and procedures: computerized tomogram: unknown result. The outcome of the events was unknown.; Sender's Comments: Based on the available information in the case, the causal association between the event neuropathy peripheral and the suspect drug cannot be excluded. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.