Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Blood thyroid stimulating hormone, Dysphagia, Gallbladder disorder, Gallbladder rupture, Hyperthyroidism
Clinical narrative: developed hyperthyroidism; lost 62-63lb in 2 months; she can't swallow; Gallbladder turned green and disintegrated; Gallbladder turned green and disintegrated; This spontaneous case was reported by a consumer and describes the occurrence of HYPERTHYROIDISM (developed hyperthyroidism), WEIGHT DECREASED (lost 62-63lb in 2 months), DYSPHAGIA (she can't swallow), GALLBLADDER DISORDER (Gallbladder turned green and disintegrated) and GALLBLADDER RUPTURE (Gallbladder turned green and disintegrated) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Gallbladder removal (was hospitalized for 6 days). Concurrent medical conditions included Asthma (had been on same medications for severe asthma for last 5 years, did not provide medication list).   On 17-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In May 2021, the patient experienced GALLBLADDER DISORDER (Gallbladder turned green and disintegrated) (seriousness criterion hospitalization) and GALLBLADDER RUPTURE (Gallbladder turned green and disintegrated) (seriousness criteria hospitalization and medically significant). On an unknown date, the patient experienced HYPERTHYROIDISM (developed hyperthyroidism) (seriousness criteria hospitalization and medically significant), WEIGHT DECREASED (lost 62-63lb in 2 months) (seriousness criterion hospitalization) and DYSPHAGIA (she can't swallow) (seriousness criterion hospitalization). The patient was hospitalized for 6 days due to GALLBLADDER DISORDER. The patient was treated with Surgery (surgery to remove the gallbladder and was hospitalized for 6 days) for Gallbladder disorder. At the time of the report, HYPERTHYROIDISM (developed hyperthyroidism), WEIGHT DECREASED (lost 62-63lb in 2 months), DYSPHAGIA (she can't swallow), GALLBLADDER DISORDER (Gallbladder turned green and disintegrated) and GALLBLADDER RUPTURE (Gallbladder turned green and disintegrated) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood thyroid stimulating hormone: not detectable not detectable. On an unknown date, Thyroxine: 2.44 (Low) Her free T4 is 2.44.         Concomitant medication taken by the patient include medications for Asthma.  About two months after the second shot her gallbladder turned green and disintegrated upon removal. Around the same time, she developed hyperthyroidism and lost 62 to 63lb in two months. She said her thyroid stimulating hormone was not detectable and her free T4 was 2.44.  Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.