Age: 49.0
Sex: M
Vaccine: COVID19
Symptoms: Blood pressure measurement, Body temperature, Heart rate, Pruritus, Rash
Clinical narrative: hive reaction to the second dose/hives/urticaria; Itching/pruritus: local; Rash: local; This spontaneous case was reported by a physician and describes the occurrence of URTICARIA (hive reaction to the second dose/hives/urticaria), PRURITUS (Itching/pruritus: local) and RASH (Rash: local) in a 49-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 007C21A and 041C21A) for COVID-19 vaccination.     The patient's past medical history included PPD skin test positive. Previously administered products included for an unreported indication: TETANUS TOXOID on 19-May-2021. Concurrent medical conditions included Food allergy (allergic to Tomatoes. Unknown reactions.), Hypertension, HIV infection and Hepatitis B. Concomitant products included DOLUTEGRAVIR SODIUM (TIVICAY) from 01-Apr-2021 to an unknown date and EMTRICITABINE, TENOFOVIR ALAFENAMIDE FUMARATE (DESCOVY) from 01-Apr-2021 to an unknown date for HIV disease, OXCARBAZEPINE (TRILEPTAL) from 17-Mar-2021 to an unknown date, ARIPIPRAZOLE (ABILIFY) and PRAZOSIN from 17-Mar-2021 to an unknown date for Malignant hyperthermia.   On 28-Apr-2021 at 11:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 26-May-2021 at 2:00 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 27-May-2021, the patient experienced URTICARIA (hive reaction to the second dose/hives/urticaria) and RASH (Rash: local). 27-May-2021, the patient experienced PRURITUS (Itching/pruritus: local). The patient was treated with LORATADINE (BENADRYL 24 FLASH) (oral) on 30-May-2021 at a dose of 25 mg; PREDNISONE (oral) on 02-Jun-2021 at a dose of 50 mg; METHYLPREDNISOLONE SODIUM SUCCINATE (SOLUMEDROL) (intramuscular) on 02-Jun-2021 at a dose of 125 mg and HYDROCORTISONE ACETATE (HYDROCORTISON ACETATE) (topical) on 30-May-2021 at a dose of 1 percent. On 08-Jun-2021, URTICARIA (hive reaction to the second dose/hives/urticaria), PRURITUS (Itching/pruritus: local) and RASH (Rash: local) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 30-May-2021, Blood pressure measurement: 117/82 mmHg (normal) 117/82 mmhg blood pressure. On 30-May-2021, Body temperature: 36.722 degree Celsius (Low) 98.1 Fahrenheit. On 30-May-2021, Heart rate: 82 heart beats per minute (normal) 82 heart beats per minute. On 30-May-2021, Respiratory rate: 16 breaths per minute (normal) 16 breaths per minute. On 02-Jun-2021, Blood pressure measurement: 102/73 mmHg (normal) 102/73 mmhg blood pressure. On 02-Jun-2021, Body temperature: 36.722 degree Celsius (Low) 98.1 Fahrenheit. On 02-Jun-2021, Heart rate: 73 heart beats per minute (normal) 73 heart beats per minute. On 02-Jun-2021, Respiratory rate: 16 breaths per minute (normal) 16 breaths per minute. On 08-Jun-2021, Blood pressure measurement: 125/80 mmHg (abnormal) 125/80 mmhg blood pressure. On 08-Jun-2021, Body temperature: 36.722 degree Celsius (Low) 98.2 Fahrenheit. On 08-Jun-2021, Heart rate: 102 heart beats per minute (High) 102 heart beats per minute. On 08-Jun-2021, Respiratory rate: 18 breaths per minute (High) 18 breaths per minute.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered URTICARIA (hive reaction to the second dose/hives/urticaria), PRURITUS (Itching/pruritus: local) and RASH (Rash: local) to have an unknown relationship.    .   Most recent FOLLOW-UP information incorporated above includes: On 03-Aug-2021: Significant follow-up added: conmeds, treatment medications, events were added.