Age: 85.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Cellulitis
Clinical narrative: two days after the second booster, arm got red had fever in it, though it was the reaction to the vaccine, then develop cellulitis; This spontaneous case was reported by a patient and describes the occurrence of CELLULITIS (two days after the second booster, arm got red had fever in it, though it was the reaction to the vaccine, then develop cellulitis) in an 85-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013B22A, 022C21A, 012A21A and 029L20A) for COVID-19 vaccination.     Concurrent medical conditions included Specific allergy (drug) (Allegra D), Blood pressure and Arrhythmia. Concomitant products included PROPRANOLOL for Arrhythmia, VITAMINS NOS and CALCIUM for an unknown indication.   On 12-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 09-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 03-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Jul-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Jul-2022, the patient experienced CELLULITIS (two days after the second booster, arm got red had fever in it, though it was the reaction to the vaccine, then develop cellulitis) (seriousness criterion medically significant). At the time of the report, CELLULITIS (two days after the second booster, arm got red had fever in it, though it was the reaction to the vaccine, then develop cellulitis) was resolving.            Patient height was reported as 5 foot and 6 inches. There was no medical history mentioned related to AE for both Acute and Chronic illnesses at the time of vaccination Concomitant medications also included unspecified blood pressure medication It was reported that two days after the second booster patient arm got red had fever in it and though it was the reaction to the vaccine and then develop cellulitis and now was better.  Patient did not receive other vaccines given within 1 month prior to Moderna COVID-19 vaccine. Patient saw the primary care physician on the 1 Aug 2022. Patient did not experienced similar event in the past. Patient never had COVID positive test or diagnosis. Treatment medications included unspecified antibiotics.  Company comment: This spontaneous case concerns 85-year-old female patient with no relevant medical history reported, who experienced the unexpected serious (medically significant) AESI event of Cellulitis that occurred in 2 days after the fourth dose of mRNA-1273 vaccine in the COVID-19 vaccination series. It was reported that two days after the second booster patient arm got red had fever in it and though it was the reaction to the vaccine and then develop cellulitis. The outcome of event was reported as resolving. The benefit-risk relationship of mRNA-1273 is not affected by this report. Event seriousness assessed as per medical judgement.   This case was linked to MOD-2022-621839 (Patient Link).; Sender's Comments: This spontaneous case concerns 85-year-old female patient with no relevant medical history reported, who experienced the unexpected serious (medically significant) AESI event of Cellulitis that occurred in 2 days after the fourth dose of mRNA-1273 vaccine in the COVID-19 vaccination series. It was reported that two days after the second booster patient arm got red had fever in it and though it was the reaction to the vaccine and then develop cellulitis. The outcome of event was reported as resolving. The benefit-risk relationship of mRNA-1273 is not affected by this report. Event seriousness assessed as per medical judgement.