Sex: F
Vaccine: VARZOS, VARZOS, VARZOS
Symptoms: Injection site pain, Injection site swelling, Pain in extremity, Pruritus, Rash
Clinical narrative: flu like symptoms; soreness at injection site; blister/rash on her face; chills/rash on her face; condition worsened; condition worsened; Condition aggravated; bruising at the injection site; swelling at the injection site; soreness at the injection site; achiness in the back of her calves; feels flushed; chilled; This case was reported by a consumer via call center representative and described the occurrence of influenza-like symptoms in a 82-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Zostavax (received on unknown date).   On an unknown date, the patient received the 1st dose of Shingrix. On an unknown date, the dose was an unknown dose. In June 2019, the patient received the 2nd dose of Shingrix. In June 2019, not applicable after receiving Shingrix and less than a month after receiving Shingrix, the patient experienced rash aggravated, pruritus aggravated, condition aggravated, injection site bruising, injection site swelling, injection site pain, pain in calf, flushing and chills. On an unknown date, the patient experienced influenza-like symptoms, injection site pain, blistery rash and itchy rash. Rechallenge with Shingrix was positive. On an unknown date, the outcome of the influenza-like symptoms was recovered/resolved and the outcome of the injection site pain, blistery rash and itchy rash were not recovered/not resolved and the outcome of the rash aggravated, pruritus aggravated, condition aggravated, injection site bruising, injection site swelling, injection site pain, pain in calf, flushing and chills were unknown.   It was unknown if the reporter considered the influenza-like symptoms, injection site pain, blistery rash and itchy rash to be related to Shingrix. It was unknown if the reporter considered the rash aggravated, pruritus aggravated, condition aggravated, injection site bruising, injection site swelling, injection site pain, pain in calf, flushing and chills to be related to Shingrix.  Additional details were provided as follows: The age at vaccination was not reported. The patient received the 1st dose of Shingrix in right arm approximately 2.5 months ago. After receiving the 1st dose, patient developed flu like symptoms, and soreness at the injection site ,rash on her face.  The rash was primarily located on her upper cheeks on both sides, the rash was blister like and itchy.  The patient stated that tried different creams that did not help. The rash started getting better and she went to see a dermatologist. Approximately 1 week ago, the patient received the 2nd dose of Shingrix and the rash had gotten worse. The patient stated that the rash was on her upper and lower cheeks. The patient also developed bruising at the injection site, swelling at the injection site, soreness at the injection site and achiness in the back of her calves. The patient stated that occasionally feels flushed and gets chilled. The reporter consented to follow up. The patient's emergency room visit required