Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Injection site pruritus, Injection site swelling, Insomnia, Movement disorder, Muscular weakness
Clinical narrative: This case was reported by a consumer via call center representative and described the occurrence of injection site erythema in a adult female patient who received SHINGRIX. Concurrent medical conditions included blood pressure. Concomitant products included lisinopril. On 20th March 2018, the patient received the 1st dose of SHINGRIX. In March 2018, less than a month after receiving SHINGRIX, the patient experienced injection site erythema, injection site swelling, injection site pain, injection site itching, shoulder pain, hypertension, pain in arm, localized muscle weakness, movement disorder and pain. On an unknown date, the patient experienced joint range of motion decreased. The patient was treated with ibuprofen, Hot Compresses and BENADRYL. On an unknown date, the outcome of the injection site erythema, injection site swelling, injection site itching, hypertension and pain were recovered/resolved and the outcome of the injection site pain, shoulder pain and pain in arm were recovering/resolving and the outcome of the joint range of motion decreased was not recovered/not resolved and the outcome of the localized muscle weakness and movement disorder were unknown. The reporter considered the injection site erythema, injection site swelling, injection site pain, injection site itching, shoulder pain, joint range of motion decreased, hypertension, pain in arm and pain to be related to SHINGRIX. It was unknown if the reporter considered the localized muscle weakness and movement disorder to be related to SHINGRIX. Additional details were provided as follows: The age at vaccination was not reported. The reporter was the patient. She did not have lot number or expiration date of product. The reporter notes she had arm pain for 8 days after she got SHINGRIX injection. She describes pain as pain in her arm and shoulder and pain at night, which experienced less than a week after vaccination. The pain in her arm and shoulder had improved since it began, but was still present. She notes that pain at night prevented her from sleeping and she had to stay in a chair through the night because it felt like her arm would explode. The pain at night fully resolved on this past Monday morning approximately one week after the injection, no exact date provided. She notes injection site pain that has improved since it began approximately eight hours after receiving SHINGRIX injection.  She notes decreased range of motion in right arm and shoulder began approximately one week after receiving SHINGRIX vaccine. The decreased range of motion had not improved or worsened since it began. She describes decreased range of motion as weakness in the shoulder and difficulty raising the right arm above her head. She notes itching, redness, swelling, and pain at injection site. The pain at injection site had improved and was now intermittent. Itching and swelling at injection site had fully resolved, no resolution date provided. She notes less than week after vaccination her blood pressure was high when she experienced pain at night and pain in her arm and shoulder. High blood pressure completely resolved when pain was controlled, no start or resolution date provided. She notes immediately after vaccination burning when the medicine went in during the injection on day of vaccination, burning fully resolved when injection was completed. She called her Doctor on day five of pain in her arm and shoulder. She went to see her Doctor on day eight of pain in arm and shoulder. Doctor instructed her to take Ibuprofen and use hot compress to treat pain. She used Ibuprofen, hot compress, and BENADRYL to treat pain. She denies emergency room visit or hospitalization to treat events reported. She declined to provide mailing address.