Age: 58.0
Sex: F
Vaccine: COVID19
Symptoms: Retinal detachment
Clinical narrative: bilateral retinal detachment/retina is getting detach form liement in both eyes, Retinal tear, Vitreous floaters; This spontaneous case was reported by a pharmacist and describes the occurrence of RETINAL DETACHMENT (bilateral retinal detachment/retina is getting detach form liement in both eyes, Retinal tear, Vitreous floaters) in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.     Past medical history and allergies were not provided. It was not provided if the patient ever had COVID + test or diagnosis. No other vaccines given within 1 month prior to Moderna COVID-19 vaccine. No AE cause patient to seek medical care (office visit, Urgent care, ER, hospitalized) and the patient did not experience a similar event in the past.  The patient's past medical history included Cataract operation in February 2021. Concurrent medical conditions included Arthritis (since she was 40 year.) and Nearsighted. Concomitant products included FENOFIBRATE, VITAMIN B COMPLEX, CALCIUM and DOCUSATE SODIUM (STOOL SOFTENER) for an unknown indication.   In January 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In February 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 12-Jul-2022, the patient experienced RETINAL DETACHMENT (bilateral retinal detachment/retina is getting detach form liement in both eyes, Retinal tear, Vitreous floaters) (seriousness criterion medically significant). The patient was treated with Surgery for Retinal detachment. At the time of the report, RETINAL DETACHMENT (bilateral retinal detachment/retina is getting detach form liement in both eyes, Retinal tear, Vitreous floaters) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   It was reported that patient had arthritis and was nearsighted and was perfectly healthy. In yearly check up patient got cataracts in one eye and had a surgery in Feb-2021 after two days everything was fine.Few months later patient noticed floaters in the eye and in her regular check up on 16-Jun-2022 the physician told that patient had a retinal tear and went to ophthalmologist on the 12-Jul-2022 patient was told that patient had bilateral retinal detachment, retina was getting detach form liement in both eyes. It was reported that symptoms were worsened. On 14-Jul-2022 patient had emergency surgery to save patient's eye sight.In follow up it was confirmed that patient had retinal detachment surgery on 14-Jul-2022. Patient had a follow up appointment in 1 month.  Company Comment: This spontaneous case concerns a 58-year-old female patient with medical history of Nearsightedness and past medical history of Cataract operation (in February 2021), who experienced the unexpected serious (medically significant) event of Retinal detachment that occurred in the context of mRNA-1273 vaccination. Latency cannot be assessed since vaccination date was not disclosed. In a yearly checkup patient got cataract in one eye and underwent surgery in Feb-2021. Few months later she noticed floaters in the eye and in her regular checkup on 16-Jun-2022 the physician detected that she had a retinal tear. After consulting ophthalmologist on the 12-Jul-2022 she was diagnosed with bilateral retinal detachment and retina was getting detach form liement in both eyes as symptoms were worsened. Two days later she underwent emergency surgery to save her eyesight. The reported outcome of the events had not resolved. Patients' medical history of Nearsightedness and past medical history of Cataract operation could be confounding for the event. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 15-Jul-2022: Live Follow-up  received and occupation of reporter, age and other relevant history of patient has been updated.; Sender's Comments: This spontaneous case concerns a 58-year-old female patient with medical history of Nearsightedness and past medical history of Cataract operation (in February 2021), who experienced the unexpected serious (medically significant) event of Retinal detachment that occurred in the context of mRNA-1273 vaccination. Latency cannot be assessed since vaccination date was not disclosed. In a yearly checkup patient got cataract in one eye and underwent surgery in Feb-2021. Few months later she noticed floaters in the eye and in her regular checkup on 16-Jun-2022 the physician detected that she had a retinal tear. After consulting ophthalmologist on the 12-Jul-2022 she was diagnosed with bilateral retinal detachment and retina was getting detach form liement in both eyes as symptoms were worsened. Two days later she underwent emergency surgery to save her eyesight. The reported outcome of the events had not resolved. Patients' medical history of Nearsightedness and past medical history of Cataract operation could be confounding for the event. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.