Age: 14.0
Sex: F
Vaccine: HPV4, HPV4
Symptoms: Migraine, Nuclear magnetic resonance imaging
Clinical narrative: PT HAD THE SECOND GARDASIL INJECTION IN SEPT '07. AND THE FOLLOWING MONTH SHE STARTED HAVING HEADACHES, ABOUT 3XS A WEEK.  THEN IT GRADUALLY INCREASED SOME WORSE THAN OTHERS. FINALLY ON JANUARY 1 '08, SHE HAD A SEVERE MIGRAINE. THAT INCAPACITATED HER FOR AN ENTIRE 2 DAYS.  THE PAIN WENT ON FOR A WEEK THEN SHE BEGAN TO GET HEART PALPS.  THEN AFTER GIVING HER MEDICINE FOR THE MIGRAINE. SHE HAD A SEIZURE ONE NIGHT. SHE WAS TAKEN TO THE E.R. BY AMBULANCE AND WAS ADMITTED FOR A DAY AND A HALF. IN ORDER TO GET CONTROL OF THE HEAD PAIN WHICH BY THIS TIME HAD BEEN CONSTANT FOR ABOUT 3WKS. FINALLY THE HOSPITAL WAS ABLE TO GET RID OF THE HEADACHE. BUT THE SAME DAY SHE WAS RELEASED WE HAD TO RETURN BECAUSE THE PAIN RETURNED WORSE. SHE WAS GIVEN PAIN MEDS I.V. AND SENT HOME. WE TRIED VARIOUS MIGRAINE MEDS AND NOTHING WORKED FOR LONG. THEN WE SAW A NEUROLOGIST WHO TREATED HER FOR ABOUT 2MNTHS. SHE HAD A COUPLE MORE SEIZURES BETWEEN THAT TIME, AND THE NEUROLOGIST ADMITTED HER AGAIN. TO START THE I.V. PAIN MED. SHE WAS ADMITTED FOR 2DYS THEN.  FINALLY HAD SOME RELIEF FOR THE FIRST TIME IN A MNTH SINCE THE LAST ADMISSION. THAT LASTED 2DYS AND THEN THE PAIN RETURNED. AND HER SEIZURES INCREASED. SHE MISSED A LOT OF SCHOOL, WAS NOT ABLE TO PLAY OR CONCENTRATE. SHE LIVED IN CONSTANT FEAR OF FALLING OUT AND HAVING INCREASED HEART PALPS. SHE HAD BOUTS OF BIGEMENY ALSO.  THIS HAS GONE ON SINCE THE 2ND SHOT OF THAT GARDASIL.  SHE HAS NEVER TAKEN MORE THAN TYLENOL FOR PAIN ALL HER LIFE. VERY ACTIVE, FUN KID. BUT FOR MONTHS SHE HAD BEEN STRUGGLING WITH THIS.  I FOLLOWED THE REPORTS ON THIS DRUG WHICH LEAD ME TO CONTACT SOMEONE ABOUT THIS. THEN DIFFERENT PEOPLE I SPEAK WITH IN DR OFFICES HAVE HAD FAMILY MEMBERS ALSO HAVE BAD REACTIONS, ALSO THE MORNING NEWS CLIP ABOUT HOW SOME OTHER YOUNG GIRLS HAD BAD REACTIONS. NOW SHE IS GETTING BETTER (PROBALLY BECAUSE SHE DID NOT HAVE THE 3RD INJECTION). BUT EVEN NOW THINGS ARE HARD FOR HER. SHE HAS REALLY BAD MIGRAINES NOW WHICH WAS NEVER AN ISSUE, AND SHE GETS TIRED EASIER NOW, MUCH EASIER. I WOULD LIKE SOME ANSWERS ABOUT THIS.MY CHILD HAS SUFFERED AND IS SUFFERING. I REALLY WOULD LIKE SOME ANSWERS PLEASE.  9/22/2008 ER record received for DOS 2/26/2008 with DX: Status Migrainosus. Pt reported for DHE tx for 4-8 wk hx of L temporal and occipital migraine pain. Pt trialed multiple meds w/o relief.  Had some relief from 1 previous dose of DHE.   09/23/2008 MR received from neurologist for OVs beginning 1/28/08-3/18/08 with initial dx migraine H/As.  Seizure-like episodes. Status migrainosus Pt initially presented following 2 ER visits-one for severe H/A, another for seizure episodes which include drooling, stiffening, shaking of extremities, and eye deviation with post-ictal state. Headaches include photophobia, phonophobia,  nausea and vomiting as well as some dizziness and double vision.  PEs WNL.  Seen 3/18/08 with recent seizure like episode. Anticonvulsants increased. 9/26/08 MR received for multiple ER visits and one admission dated January 15,17 and 20 2008 and March 16, 08. Initial DX: Headache.  Admitted 1/20/08 with DX:  Seizure-new onset.  Neuro consult (+) for diplopia,  sluggish reflexes.  Impression:  New onset status migrainosus. 1/27/2010 She still suffers from severs migraines and seizures.