Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: Gait disturbance, Inflammation, Interchange of vaccine products, Joint dislocation, Meniscus injury
Clinical narrative: found the blood clots in her left foot; meniscus in her left knee; And toe on her left foot came out of the joint and was on top of the big toe; pain; one day she just stepped over and fell to her knee; States that her calf area was still swollen; like a chronic inflammation in her body; lost all of her hair in the body; she tripped her foot on a balcony in Jul2022; gave her permission to have surgery for her hammer toe; Dose 1 and 2 Moderna/Dose 3 Pfizer; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team, Program ID: (Unknown). The reporter is the patient.  A 63-year-old female patient received BNT162b2 (BNT162B2), on 05Dec2021 as dose 3 (booster), single (Batch/Lot number: unknown) at the age of 62 years for covid-19 immunisation. The patient's relevant medical history included: "Cholesterol" (unspecified if ongoing). Concomitant medication(s) included: ROSUVASTATIN taken for blood cholesterol, start date: 2022. Past drug history included: Xarelto. Vaccination history included: moderna coviD-19 vaccine (Dose: 1, Batch/lot number: Unknown), administration date: 06Jan2021, when the patient was 61-year-old, for COVID-19 Immunization, reaction(s): "the conditions of her hair; it became oily and unhealthy"; moderna coviD-19 vaccine (Dose: 2, Batch/lot number: Unknown), administration date: 09Feb2021, when the patient was 61-year-old, for COVID-19 Immunization, reaction(s): "the conditions of her hair; it became oily and unhealthy"; moderna coviD-19 vaccine (Dose: 2, Batch/lot number: Unknown), administration date: 09Feb2021, for COVID-19 Immunization, reaction(s): "she started to lose her hair". The following information was reported: INTERCHANGE OF VACCINE PRODUCTS (non-serious) with onset 05Dec2021, outcome "unknown", described as "Dose 1 and 2 Moderna/Dose 3 Pfizer"; FOOT DEFORMITY (medically significant) with onset 2022, outcome "unknown", described as "gave her permission to have surgery for her hammer toe"; GAIT DISTURBANCE (non-serious) with onset Jul2022, outcome "unknown", described as "she tripped her foot on a balcony in Jul2022"; THROMBOSIS (medically significant), outcome "unknown", described as "found the blood clots in her left foot"; MENISCUS INJURY (medically significant), outcome "unknown", described as "meniscus in her left knee"; JOINT DISLOCATION (medically significant), outcome "unknown", described as "And toe on her left foot came out of the joint and was on top of the big toe"; ALOPECIA (non-serious), outcome "not recovered", described as "lost all of her hair in the body"; PAIN (non-serious), outcome "unknown"; FALL (non-serious), outcome "unknown", described as "one day she just stepped over and fell to her knee"; PERIPHERAL SWELLING (non-serious), outcome "unknown", described as "States that her calf area was still swollen"; INFLAMMATION (non-serious), outcome "unknown", described as "like a chronic inflammation in her body". The patient underwent the following laboratory tests and procedures: Antibody test: (unspecified date) Positive, notes: The test she had done only resulted as positive; (2022) 212; (Jul2022) 25,720; (Aug2022) Unknown results, notes: One month later she did another antibody test; Blood test: (unspecified date) hair loss was from the vaccine.; (unspecified date) high antibody count could cause blood clots, notes: she did blood work because she said that a high antibody count could cause blood clots; Ultrasound Doppler: (01Feb2022) they found no blood clots, notes: The doctor sent her for another doppler test on 01Feb2023, and they found no blood clots, but stated that she still has a spot there where the clots were; (14May2022) found the blood clots in her left foot, notes: he sent her for a doppler test on 14May2022 and found the blood clots in her left foot. Therapeutic measures were taken as a result of thrombosis, meniscus injury, joint dislocation, foot deformity, alopecia.  Clinical course details: The patient stated that she lost all her hair on her body after receiving the Pfizer COVID vaccine booster. She described that she has total alopecia and lost all of her hair in the body. The patient was asking for treatments from Pfizer and was also looking for available trials that can help her alopecia. After the first vaccine, she lost her hair, then it started to grow back after some treatment, then after she received the "2nd vaccine" on 05Dec2021 she lost all of her hair on her body. She was then diagnosed with alopecia. The patient clarified that her first two doses of the COVID 19 Vaccine were from Moderna. The first Moderna dose was received on 06Jan2021 and the second Moderna dose was received on 09Feb2021. The Pfizer COVID 19 Booster was received on 05Dec2021.  After she received the Moderna COVID 19 vaccines, she started to notice that the conditions of her hair became oily and unhealthy. She tried to use conditioner. Immediately after the second Moderna vaccine, she started to lose her hair, so she saw her doctor on 23Feb2021, and he sent her to a dermatologist. She thought that it was the Moderna vaccine that caused the change in her hair, so she got the Pfizer COVID 19 booster. After she got the Pfizer Covid 19 Booster, she completely lost all her hair. Again stated that after the Moderna vaccines she lost her hair partly, so she was blaming Moderna, so she did the Pfizer booster after which she lost all her hair. She then went to a Dermatologist. Stated that she got the vaccines because everybody was getting the vaccines, and she was working as an interpreter at a school. Stated that she had to sign up online because there wasn't even enough vaccine for everyone.  She started losing her hair after getting the Moderna vaccine around the end of Jan2021 or beginning of Feb2021. By the end of Apr2022 all her hair was gone. Since losing all her hair, it stayed the same, it's not growing back. She went to see a nutritionist and a dermatologist and nothing helped. She spent a lot of money on treatments and medications and still nothing helped. She doesn't know what helped her hair start growing back after receiving the Moderna vaccines, so she did the same steps after getting the Pfizer booster and losing all her hair. She saw the dermatologist and got 2 steroid shots 1 month apart. She used something on her hair, called Rogaine, which she was still using. The patient only has a brand new bottle of Rogaine that she has not used yet. After the Moderna vaccine, she was seeing another dermatologist who prescribed another medication that she put on her hair that smelled very badly. She doesn't know the name of this product. After getting the Pfizer COVID 19 Booster, she tried the nutritionist, got 2 steroid shots and nothing came back; she has no hair on her body at all; no hair on her eye lids, eye brows, or even private parts. She went to see another doctor and she prescribed the medication tofacitnib 4 percentage solution, which is in a tiny clear liquid bottle; she started using this on Monday. With the Pfizer COVID 19 Booster, she also had blood clots in her left foot. Stated that one day she just stepped over and fell to her knee. Then her leg started to swell in the calf area. She went to a knee doctor who said that she had to have surgery to fix her meniscus in her left knee. She had the surgery on 03May2022. States that her calf area was still swollen and remained swollen. When she went back to the doctor to take the stitches out, he saw that her calf was still swollen and he sent her for a doppler test on 14May2022 and found the blood clots in her left foot. States that she just stopped taking the medication Xarelto and returned to Aspirin. The doctor sent her for another doppler test on 01Feb2023, and they found no blood clots, but stated that she still has a spot there where the clots were. Stated that she just started to take the cholesterol medication, Rosuvastatin 10mg, about 3-4 months ago. The patient had no other vaccinations within four weeks prior to the first administration date of the suspect vaccine. States that this is frustrating. She previously had huge, big, blonde hair. She did eyebrow tattoos, but can't do anything about not having any eyelashes. She also went to see an Immunologist, who did blood work and told her that the hair loss was from the vaccine. Stated that it's like a chronic inflammation in her body and recommended that she do another test in 5-6 months. The Immunologist told her that she doesn't think she will ever get her hair back. She went to see another doctor at a clinic, who looked at her blood work, but didn't see anything there, and advised her to see a dermatologist. So she returned back to the dermatologist. States that she went to see what is going out there and while there she did an antibody test which resulted as 25,720. This was in the middle of Jul2022. States that when she did the test, the whole clinic looked at her like she was an alien. One month later she did another antibody test. She went to a Vascular doctor who gave her permission to have surgery for her hammer toe. The doctor only gave her permission for the surgery after she did blood work because she said that a high antibody count could cause blood clots. She did an antibody test at the end of Nov2022 or beginning of Dec2022; result was 212. Clarified that she tripped her foot on a balcony in Jul2022, she thought that she broke her toe but didn't. States that the secnd toe on her left foot came out of the joint and was on top of the big toe. At first it was just pain, but then the doctor saw the signs of her toe being over her big toe and said she had to have surgery. The surgery was on 14Dec2022. The doctor here said 0.8 in the line for antibodies. Any number below 0.8 is no antibodies, but above any number above 0.8 means she does have antibodies. The test she had done only resulted as positive, but the vascular doctor needed the specific antibody number, so they sent her blood to the clinic to get the specific antibody result. Stated that she wants some help from Pfizer. Maybe Pfizer knows if there are medications or treatments that can help her. States that she knows of other people that have lost their hair. Clarified that she went to the wig store, and they said that a 14-year-old girl also lost her hair after getting the vaccine (the patient had no other information to provide for the 14-year-old girl, including Manufacturer/Lot/NDC/Expiry of the vaccine the girl received).  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.