chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 60.0
Sex: F
Vaccine: FLU3
Symptoms: Joint range of motion decreased, Musculoskeletal pain, Pain in extremity, Wrong technique in drug usage process
Clinical narrative: Pain in left shoulder and arm radiating to fingers.  Deceased range of motion; received cortisone shot and physical therapy to improve symptoms.  Injection given near top of left shoulder.  Pain continues.
Age: 24.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site pain, Joint range of motion decreased, Musculoskeletal pain, Pain, Pain in extremity
Clinical narrative: Sharp pain on injection; consistent aching in shoulder and down arm limiting range of motion; currently in physical therapy. Injection given near top of left shoulder. Pain continues.
Age: 24.0
Sex: F
Vaccine: FLU3
Symptoms: Wrong technique in drug usage process
Clinical narrative: Sharp pain on injection; consistent aching in shoulder and down arm limiting range of motion; currently in physical therapy. Injection given near top of left shoulder. Pain continues.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Joint range of motion decreased, Musculoskeletal pain, Pain, Wrong technique in drug usage process
Clinical narrative: Pain in left shoulder and arm upon movement. Decreased range of motion; injection given near top of left shoulder. Pain x 8 weeks.
Age: 52.0
Sex: F
Vaccine: FLU3
Symptoms: Immediate post-injection reaction, Musculoskeletal pain, Pain in extremity, Wrong technique in drug usage process
Clinical narrative: Pain started immediately with vaccination; localized to left shoulder with pain shooting down arm to elbow, wrist and thumb; injection given near top of left shoulder. Pain x 4 months.
Age: 58.0
Sex: F
Vaccine: FLU3
Symptoms: Asthenia, Immediate post-injection reaction, Injected limb mobility decreased, Injection site pain, Wrong technique in drug usage process
Clinical narrative: Immediate pain following vaccine administration; decreased strength and range of motion; unable to lift arm over head; alleviated by high doses of Ibuprofen; injection given near top  of left shoulder. Pain x 4 weeks.
Age: 36.0
Sex: F
Vaccine: FLU(H1N1), FLU3
Symptoms: Dyspnoea, Lacrimation increased, Nasal congestion, Oropharyngeal pain, Sensation of foreign body
Clinical narrative: began feeling like there was a large lump in throat. Slight difficulty breathing, eyes watering, nose congested, sore throat. Lasted 2 days. Have previously taken influenza shot, no H1N1.
Age: 2.0
Sex: M
Vaccine: FLU(H1N1)
Symptoms: Unevaluable event
Clinical narrative: None stated
Age: 4.0
Sex: M
Vaccine: DTAPIPV, MMR
Symptoms: Full blood count, Injection site erythema, Injection site oedema, Injection site swelling
Clinical narrative: Left arm swollen and red (deltoid area).  The next day 8 X 9 cm diameter with Erythema / edema.
Age: 19.0
Sex: M
Vaccine: HEPAB, TYP, YF
Symptoms: Cough, Dyspnoea, Ear congestion, Eye pruritus, Flushing
Clinical narrative: This 19 year old received third TWINRIX (SKB AHABB162BA) and first yellow fever (1F582AA and TYPHOID vaccinations afternoon of 24 Feb 2010.  Approximately 1 hour later after returning to his vehicle with group, he began to experience bilateral water itchy eyes and diffuse scalp itching.  He immediately returned to medical where his symptoms quickly progressed to tightness in his throat, shortness of breath, facial flushing sinus/ ear congestion, coughing, and pruritic hives to face/upper torso and extremities (witness by provider).  He was treated with 50 mg oral BENADRYL and SQ epinephrine (EPIPEN) with resolution of most symptoms within 5 minutes.  Hives and itching resolved after 25 minutes.  He was observed 1 hour and released to roommate.  SM reported no reoccurrence of symptoms 24 & 48 hours later and is using CLARITIN 10 mg daily X 5 then prn.  Activities 2/24/2010 included routine morning exercises then ate a chicken bacon sandwich from a deli with a cherry soda about 1 hour before vaccinations.  He denied any new deodorants, clothing, soaps, shampoos, (or exposure to), or food intake.  He took no vitamins or herbal supplements.
Age: 19.0
Sex: M
Vaccine: HEPAB, TYP, YF
Symptoms: Lacrimation increased, Pruritus, Radioallergosorbent test positive, Sinus congestion, Skin test positive
Clinical narrative: This 19 year old received third TWINRIX (SKB AHABB162BA) and first yellow fever (1F582AA and TYPHOID vaccinations afternoon of 24 Feb 2010.  Approximately 1 hour later after returning to his vehicle with group, he began to experience bilateral water itchy eyes and diffuse scalp itching.  He immediately returned to medical where his symptoms quickly progressed to tightness in his throat, shortness of breath, facial flushing sinus/ ear congestion, coughing, and pruritic hives to face/upper torso and extremities (witness by provider).  He was treated with 50 mg oral BENADRYL and SQ epinephrine (EPIPEN) with resolution of most symptoms within 5 minutes.  Hives and itching resolved after 25 minutes.  He was observed 1 hour and released to roommate.  SM reported no reoccurrence of symptoms 24 & 48 hours later and is using CLARITIN 10 mg daily X 5 then prn.  Activities 2/24/2010 included routine morning exercises then ate a chicken bacon sandwich from a deli with a cherry soda about 1 hour before vaccinations.  He denied any new deodorants, clothing, soaps, shampoos, (or exposure to), or food intake.  He took no vitamins or herbal supplements.
Age: 19.0
Sex: M
Vaccine: HEPAB, TYP, YF
Symptoms: Throat tightness, Urticaria
Clinical narrative: This 19 year old received third TWINRIX (SKB AHABB162BA) and first yellow fever (1F582AA and TYPHOID vaccinations afternoon of 24 Feb 2010.  Approximately 1 hour later after returning to his vehicle with group, he began to experience bilateral water itchy eyes and diffuse scalp itching.  He immediately returned to medical where his symptoms quickly progressed to tightness in his throat, shortness of breath, facial flushing sinus/ ear congestion, coughing, and pruritic hives to face/upper torso and extremities (witness by provider).  He was treated with 50 mg oral BENADRYL and SQ epinephrine (EPIPEN) with resolution of most symptoms within 5 minutes.  Hives and itching resolved after 25 minutes.  He was observed 1 hour and released to roommate.  SM reported no reoccurrence of symptoms 24 & 48 hours later and is using CLARITIN 10 mg daily X 5 then prn.  Activities 2/24/2010 included routine morning exercises then ate a chicken bacon sandwich from a deli with a cherry soda about 1 hour before vaccinations.  He denied any new deodorants, clothing, soaps, shampoos, (or exposure to), or food intake.  He took no vitamins or herbal supplements.
Sex: U
Vaccine: OPV
Symptoms: Facial palsy, Paralysis flaccid
Clinical narrative: This case was reported in a literature article and described the occurrence of facial palsy in a child subject of unspecified gender who was vaccinated with Oral polio vaccine (manufacturer unspecified), DTPw and hepatitis B vaccine. The present retrospective study of acute flaccid paralysis was conducting using computerized diagnosis data and medical record review of potential cases among children aged 1 month to less than 15 year and diagnosed from 1 January 1992 through 31 December 1998. The subjects were hospitalized or seen in the emergency room. None of the children were known to have a preexisting immunocompromising condition. The literature article included the description of 16 children with vaccine exposure prior to development of paralytic syndrome (B0642827A, B0642828A, B0642829A, B0642830A, B0642832A, B0642836A, B0642841A, B0642846A, B0642847A, B0642848A, B0642849A, B0642850A, B0642851A, B0642811A, B0642811A). On an unspecified date the subject received unspecified dose of Oral polio vaccine, unspecified dose of hepatitis B and unspecified dose of DTPw. Forty three days after vaccination with DTPw, Hepatitis B vaccine and Oral polio vaccine, the subject experienced facial palsy. This case was assessed as medically serious by GSK. At the time of reporting the outcome of the events was unspecified. The author considered that internationally, there are advantages to using oral polio vaccine, but the stability of vaccine-derived oral polio vaccine viruses remained a concern and importation of such neurovirulent isolates to nonendemic areas remained an important risk.
Sex: U
Vaccine: OPV
Symptoms: Myositis, Paralysis flaccid
Clinical narrative: This case was reported in a literature article and described the occurrence of acute myositis in a child subject of unspecified gender who was vaccinated with Oral polio vaccine (manufacturer unspecified), DT. The present retrospective cohort study of acute flaccid paralysis was conducing using computerized diagnosis data and medical record review of potential cases among children aged 1 month to less than 15 year and diagnosed from 1 January 1992 through 31 December 1998. The subjects were hospitalized or seen in the emergency room. None of the children were known to have a preexisting immunocompromising condition. The literature article included the description of 16 children with vaccine exposure prior to development of paralytic syndrome (B0642828A, B0642829A, B0642830A, B0642832A, B0642836A, B0642841A, B0642846A, B0642847A, B0642848A, B0642849A, B0642850A, B06428511A, B0642852A, B0642853A). On an unspecified date the subject received unspecified dose of Oral polio vaccine, unspecified dose of DT vaccine. Twenty five days after vaccination with DT and Oral polio vaccine, the subject experienced acute myositis. This case was assessed as medically serious by GSK. At the time of reporting the outcome of the events was unspecified. The author considered that internationally, there are advantages to using oral polio vaccine, but the stability of vaccine-derived oral polio vaccine viruses remained a concern and importation of such neurovirulent isolateds to nonendemic areas remained an important risk.
Sex: U
Vaccine: OPV
Symptoms: Guillain-Barre syndrome, Paralysis flaccid
Clinical narrative: This case was reported in a literature article and described the occurrence of Guillain Barre Syndrome in a child subject of unspecified gender who was vaccinated with Oral polio vaccine, manufacturer unspecified and DTPa. The present retrospective cohort study flaccid paralysis  was conducting using computerized diagnosis data and medical record review of potential cases among children aged 1 month to less than 15 year and diagnosed from 1 January 1992 through 31 December 1998. The subject were hospitalized or seen in the emergency room. None of the children were known to have a preexisting immunocompromising condition. The article included the description of 16 children with vaccine exposure prior to development of paralytic syndrome (B0642827A, B0642828A, B0642829A, B0642811A, B0642830A, B0642836A, B0642841A, B0642832A, B0642846A, B0642847A, B0642848A, B0642850A,B0642851A, B0642852A, B0642853A. On an unspecified date the subject received unspecified dose of DTPa and unspecified dose of Oral polio vaccine. Two days after vaccination with Oral polio vaccine and DTPa, the subject experienced Guillain Barre Syndrome. This case was assessed as medically serious by GSK. At the time of reporting the outcome of the events was unspecified. The author considered that internationally, there are advantages to using oral polio vaccine, but the stability of vaccine-derived oral polio vaccine viruses remained a concern and importation of such neurovirulent isolated to non endemic areas remained an important risk.
Sex: U
Vaccine: DTAP
Symptoms: Paralysis, Vaccination complication
Clinical narrative: This case was reported in a literature article and described the occurrence of paralysis in a child subject of unspecified gender who was vaccinated with DTPA. The present retrospective cohort study of acute flaccid paralysis was conducing using computerized diagnosis data and medical record review of potential cases among children aged 1 month to less than 15 year and diagnosed from 1 January 1992 through 31 December 1998. The subjects were hospitalized or seen in the emergency room None of the children were known to have a preexisting immunocompromising condition. The literature article included the description of 16 children with vaccine exposure prior to development of paralytic syndrome (B0642827A, B0642828A, B0642829A, B0642811A, B0642830A, B0642836A, B0642841A, B0642832A, B0642846A, B0642847A, B0642849A, B0642850A, B0642851A, B0642852A, B0642853A). Concurrent vaccination included oral POLIO vaccine (manufacturer unspecified), On unspecified date the subject received unspecified dose of DTPA. On the day of vaccination with DTPA, the subject experienced paralysis. This case was assessed as medically serious by GSK. At the time of reporting the outcome of the events was unspecified. The clinical diagnosis was adverse reaction to DTPA vaccine.
Age: 60.0
Sex: F
Vaccine: TDAP
Symptoms: Arthralgia, Hypersensitivity, Oropharyngeal pain, Pain in extremity, Pyrexia
Clinical narrative: Sore throat, sore arm, joint pain, low grade fever.  Saw MD and was told was having an allergic reaction. "Throat closing" given inhaled steroids, BENADRYL by PMD. 3/23/10.
Age: 60.0
Sex: F
Vaccine: TDAP
Symptoms: Throat tightness
Clinical narrative: Sore throat, sore arm, joint pain, low grade fever.  Saw MD and was told was having an allergic reaction. "Throat closing" given inhaled steroids, BENADRYL by PMD. 3/23/10.
Age: 80.0
Sex: F
Vaccine: FLU(H1N1)
Symptoms: Burning sensation, Dizziness, Swelling, Throat irritation
Clinical narrative: Itchy, burning sensation in throat dizzy, 2 hrs after getting H1N1 shot. Pt has to go to emergency room for swelling.
Age: 11.0
Sex: F
Vaccine: FLU(H1N1), FLU3, HPV4, MNQ, TDAP
Symptoms: Syncope
Clinical narrative: Syncope approximately three minutes after injections.  Pt. placed supine with lower extremities elevated; instant return of skin color to pink and conscienceness.  BP - 98/70 pulse 78 O2 SaO2 - 95 %.  Vitals rechecked at five minutes.  BP - 104/68 pulse 86 SaO2 97%.
Sex: F
Vaccine: FLU(H1N1)
Symptoms: Arthralgia, Injection site pain
Clinical narrative: Has pain in upper L arm near joint. Describes pain as Level 5 on a scale of 1-10. No redness or swelling. Stated she's not sure if pain is from flu shot. States she fell in early Feb at work.
Age: 81.0
Sex: F
Vaccine: FLU(H1N1)
Symptoms: Malaise, Pneumonia
Clinical narrative: 10 days after vaccine administration patient went to ER not feeling well. Patient was diagnosed with pneumonia. Admitted on 2-2-10 and released on 2-11-10.
Age: 85.0
Sex: M
Vaccine: FLU(H1N1)
Symptoms: Malaise, Pneumonia
Clinical narrative: 10 days after vaccine administration went to ER not feeling well, had pneumonia. Admitted on 2-2-10, released 2-12-10.
Age: 0.01
Sex: F
Vaccine: FLU(H1N1), FLU3, HIBV, MMR, VARCEL
Symptoms: Chest X-ray normal, Convulsion, Injection site erythema, Irritability, Pulse pressure decreased
Clinical narrative: Client had runny nose, low grade temps and had been fussy since 1/22/2010.  Mother had been giving child Tylenol and Motrin for low grade fevers. Client had been fine all day, but became very fussy after dinnertime.  Mother had been giving child a bath when the child became very restless and stood up in the tub suddenly.  The mother took the child out of the bath and laid her on the floor after she began shaking.  Mother stated that she was having a seizure.  She states that her husband provided rescue breaths because the girl had stopped breathing.  Her pulse was faint as well, but the girl began breathing on her own.  Child was transported to ER by ambulance where she was evaluated, treated and released.  Her temperature was over 103 degrees and she was given Tylenol and an antibiotic.  Chest x-ray negative and they were unable to get a urine sample.  Mother noticed that child had a red circle the day before (1/22/2010) where the varicella had been given.  Child has made a full recovery and is working with MD on vaccinations.
Age: 0.01
Sex: F
Vaccine: FLU(H1N1), FLU3, HIBV, MMR, VARCEL
Symptoms: Pyrexia, Respiratory arrest, Restlessness, Rhinorrhoea, Tremor
Clinical narrative: Client had runny nose, low grade temps and had been fussy since 1/22/2010.  Mother had been giving child Tylenol and Motrin for low grade fevers. Client had been fine all day, but became very fussy after dinnertime.  Mother had been giving child a bath when the child became very restless and stood up in the tub suddenly.  The mother took the child out of the bath and laid her on the floor after she began shaking.  Mother stated that she was having a seizure.  She states that her husband provided rescue breaths because the girl had stopped breathing.  Her pulse was faint as well, but the girl began breathing on her own.  Child was transported to ER by ambulance where she was evaluated, treated and released.  Her temperature was over 103 degrees and she was given Tylenol and an antibiotic.  Chest x-ray negative and they were unable to get a urine sample.  Mother noticed that child had a red circle the day before (1/22/2010) where the varicella had been given.  Child has made a full recovery and is working with MD on vaccinations.
Age: 46.0
Sex: M
Vaccine: FLU(H1N1)
Symptoms: Dizziness, Flushing, Heart rate increased, Immediate post-injection reaction, Influenza
Clinical narrative: Shot felt like rubbing alcohol burning at site. Instantly dizzy, flushed, rapid heart rate, nausea. Went from Healthy to Flu symptoms over night. Was very sick in 48 hrs, stayed very sick for 3 weeks.
Age: 46.0
Sex: M
Vaccine: FLU(H1N1)
Symptoms: Injection site pain, Malaise, Nausea
Clinical narrative: Shot felt like rubbing alcohol burning at site. Instantly dizzy, flushed, rapid heart rate, nausea. Went from Healthy to Flu symptoms over night. Was very sick in 48 hrs, stayed very sick for 3 weeks.
Age: 30.0
Sex: F
Vaccine: TDAP
Symptoms: Blood test normal, Burning sensation, Pruritus, Rash erythematous, Rash macular
Clinical narrative: About 24 hours after vaccine administration I broke out in severe hives on my arms and legs.  It appeared to be a rash all over the extremities with large red raised blotches that itched and burned severely.
Age: 30.0
Sex: F
Vaccine: TDAP
Symptoms: Urticaria
Clinical narrative: About 24 hours after vaccine administration I broke out in severe hives on my arms and legs.  It appeared to be a rash all over the extremities with large red raised blotches that itched and burned severely.
Age: 60.0
Sex: F
Vaccine: VARZOS
Symptoms: Burning sensation, Oedema peripheral, Skin warm, Tenderness
Clinical narrative: Burning sensation, then tenderness, then moderate swelling (3-23-10)above and then below elbow (3-26-10) and then hot to the touch (3-25-10). Nurse strongly recommended that client visit clinic physician today or tomorrow and she stated that she would. Client stated that she did start to take Benadryl on 3/23/10.
Age: 1.2
Sex: M
Vaccine: HEPA, MMR, PNC, VARCEL
Symptoms: Lymphadenopathy, Rash vesicular
Clinical narrative: Vesicular Rash with swollen lymph nodes
Age: 0.16
Sex: M
Vaccine: DTAPIPVHIB, HEP, RV1
Symptoms: Metabolic function test, Pneumonia, Respiratory syncytial virus infection, Wheezing
Clinical narrative: Wheezing,pneumonia,RSV. Admitted to the hospital 03/18/2010.
Age: 5.0
Sex: F
Vaccine: PPV
Symptoms: Back pain, Cellulitis, Erythema, Injection site erythema, Injection site swelling
Clinical narrative: swelling, erythema of L shoulder spreading to back, painful, appears consistent with cellulitis
Age: 5.0
Sex: F
Vaccine: PPV
Symptoms: Swelling
Clinical narrative: swelling, erythema of L shoulder spreading to back, painful, appears consistent with cellulitis
Age: 24.0
Sex: F
Vaccine: TDAP
Symptoms: Asthenia, Dizziness, Feeling cold, Injection site pain, Loss of consciousness
Clinical narrative: At 2:Am I woke up freezing even though the heat was on high, I had goose bumps all over my body for hours. Then the injection spot became very painful. Hours later, I tried to get up, but every muscle my body felt like I got beat up, I was weak, nauseous, dizzy, I black out while taking a shower and almost threw up. I was weak and shaky for the rest of the day. I took some 800ml ibuprofen and slept the rest off. I feel better now, (the next day). But still a little weak in the muscles and stomach.
Age: 24.0
Sex: F
Vaccine: TDAP
Symptoms: Muscular weakness, Nausea, Piloerection, Tremor
Clinical narrative: At 2:Am I woke up freezing even though the heat was on high, I had goose bumps all over my body for hours. Then the injection spot became very painful. Hours later, I tried to get up, but every muscle my body felt like I got beat up, I was weak, nauseous, dizzy, I black out while taking a shower and almost threw up. I was weak and shaky for the rest of the day. I took some 800ml ibuprofen and slept the rest off. I feel better now, (the next day). But still a little weak in the muscles and stomach.
Age: 30.0
Sex: M
Vaccine: FLU3, HEPA, TDAP
Symptoms: Convulsion, Flushing, Mydriasis, Pallor, Posturing
Clinical narrative: POST VACCINATIONS PATIENT SUFFERED SEIZURE LASTING APPROXIMATELY 5 SECONDS EVIDENCED BY POSTURING OF EXTREMITIES, DILATED PUPILS, NONRESPONSIVE TO VERBAL COMMANDS OR PHYSICAL STIMULI, FACE INITIALLY PALE THEN FLUSHED.
Age: 30.0
Sex: M
Vaccine: FLU3, HEPA, TDAP
Symptoms: Unresponsive to stimuli
Clinical narrative: POST VACCINATIONS PATIENT SUFFERED SEIZURE LASTING APPROXIMATELY 5 SECONDS EVIDENCED BY POSTURING OF EXTREMITIES, DILATED PUPILS, NONRESPONSIVE TO VERBAL COMMANDS OR PHYSICAL STIMULI, FACE INITIALLY PALE THEN FLUSHED.
Age: 0.16
Sex: M
Vaccine: DTAP, HIBV, IPV, PPV
Symptoms: Screaming
Clinical narrative: screaming inconsolably all day
Age: 8.0
Sex: F
Vaccine: VARCEL
Symptoms: Urticaria
Clinical narrative: Hives all over body
Age: 11.0
Sex: F
Vaccine: MNQ, TDAP
Symptoms: Erythema, Pruritus, Skin warm
Clinical narrative: Redness, Hot to touch, itchy 6cm x 6cm
Age: 4.0
Sex: F
Vaccine: DTAPIPV
Symptoms: Injection site erythema, Injection site nodule, Injection site swelling, Injection site warmth
Clinical narrative: Swollen, reddened & warm to the touch bump on L arm.
Age: 3.0
Sex: M
Vaccine: MMR
Symptoms: Aggression, Agitation, Crying, Dysphemia, Neurological symptom
Clinical narrative: Uncontrollable tantrums, crying, stuttering.  Very agitated and just not like himself.  The symptoms started not long after his vaccination with the MMR shot.  He had been talking from the time he was 1 year old with no problems.  After this shot he started stuttering and having problems with his thought processes. For days he had problems with crying and tantrums.  I took a good 6 months before he stopped stuttering.  He still has some neurological issues that may be associated with this vaccination.
Age: 3.0
Sex: M
Vaccine: MMR
Symptoms: Thinking abnormal
Clinical narrative: Uncontrollable tantrums, crying, stuttering.  Very agitated and just not like himself.  The symptoms started not long after his vaccination with the MMR shot.  He had been talking from the time he was 1 year old with no problems.  After this shot he started stuttering and having problems with his thought processes. For days he had problems with crying and tantrums.  I took a good 6 months before he stopped stuttering.  He still has some neurological issues that may be associated with this vaccination.
Age: 39.0
Sex: F
Vaccine: TDAP
Symptoms: Injection site cellulitis, Injection site erythema, Injection site rash, Injection site swelling, Injection site warmth
Clinical narrative: Initial report received on 16 and 18 March 2010 from a health care professional. A 39-year-old female patient had received a first left deltoid (route not provided) dose of ADACEL (lot number U2936BA, Sanofi Pasteur SA lot number C3170) on 12 March 2010. The patient had no known allergies, but had an upper respiratory infection at the time, for which she was taking Albuterol and QVAR inhalers. The following day after vaccination, the patient experienced localized cellulitis and erythema described as red, swollen, raised mark, that was warm to the touch at the injection site. She was evaluated in the doctor's office three days later, and the area was observed to be 9 cm by 6 cm. The patient was treated for cellulitis with Septra. It was not reported whether the patient underwent diagnostic testing for confirmation of cellulitis. At the time of this report, the patient had not recovered. Documents held by sender: None.
Age: 44.0
Sex: M
Vaccine: TTOX
Symptoms: Blood creatine phosphokinase increased, CSF protein increased, Clostridium test positive, Dysphagia, Electromyogram normal
Clinical narrative: A 44-year old male patient received an injection of TETANUS TOXOID (manufacturer and lot number not reported). Approximately 9 years post-vaccination, he was diagnosed with generalized tetanus. The patient had a history of multiple shrapnel and gunshot wounds from military service, and had no history of neuromuscular disease. He worked as a contractor and had sustained many nail-related injuries over the previous years, including an accident 6 months prior to presentation when he drove a nail into his left ankle with a nail gun. He removed the nail with a crowbar and did not seek medical care; he could not remember a more recent injury. Approximately 4 weeks prior to presentation, the patient developed an itching sensation in his right calf, which ascended to his right leg and began to involve his left leg. He subsequently developed muscle spasms in his right calf, which were intensely painful, sudden in onset, and up to 10 minutes duration. One week prior to presentation, the spasms began to occur more regularly. He developed trismus, dysphagia, and laryngospasms, with one episode resulting in several broken teeth. He had frequent, sudden urges to urinate, and lost 20 pounds unintentionally. Upon presentation, he had left cranial nerve VI palsy, an exaggerated gag reflux, and a positive jaw jerk. The wound on his left ankle had healed. Normal strength and sensation were noted in all limbs, but muscle tone was increased. His patellar and ankle reflexes were "pathologically brisk", and he had bilateral positive Babinski signs. A CBC and comprehensive metabolic panel were within normal limits. Creatinine kinase was elevated at 1446 units/L. A lumbar puncture showed a protein level of 57 mg/dL in the cerebrospinal fluid, but no pleocytosis. Nerve conduction studies were essentially normal, except for the presence of afterpotentials following slow repetitive stimulation, suggesting peripheral nerve hyperexcitability. Needle electromyography studies were normal. Tetanus antibody levels were noted to be 2.78IU/mL (protective level defined as 0.01 IU/mL). The patient was diagnosed with generalized tetanus, and was admitted to the hospital where he was treated with baclofen, benzodiazepines, 5000 unites of human tetanus immune globulin, and a 7-day course of metronidazole despite the absence of an obvious wound site. At a 3-month follow-up visit, all of the patient's symptoms had resolved. The authors noted that the patient's antibody levels could reflect "either prior vaccination or immunostimulation from active tetanus". They also speculated that the patient's milder course of disease "may also have been related to his high level of antibody". Documents held by sender: None.
Age: 44.0
Sex: M
Vaccine: TTOX
Symptoms: Extensor plantar response, Hyperreflexia, Hypertonia, Immunoglobulin therapy, Laryngospasm
Clinical narrative: A 44-year old male patient received an injection of TETANUS TOXOID (manufacturer and lot number not reported). Approximately 9 years post-vaccination, he was diagnosed with generalized tetanus. The patient had a history of multiple shrapnel and gunshot wounds from military service, and had no history of neuromuscular disease. He worked as a contractor and had sustained many nail-related injuries over the previous years, including an accident 6 months prior to presentation when he drove a nail into his left ankle with a nail gun. He removed the nail with a crowbar and did not seek medical care; he could not remember a more recent injury. Approximately 4 weeks prior to presentation, the patient developed an itching sensation in his right calf, which ascended to his right leg and began to involve his left leg. He subsequently developed muscle spasms in his right calf, which were intensely painful, sudden in onset, and up to 10 minutes duration. One week prior to presentation, the spasms began to occur more regularly. He developed trismus, dysphagia, and laryngospasms, with one episode resulting in several broken teeth. He had frequent, sudden urges to urinate, and lost 20 pounds unintentionally. Upon presentation, he had left cranial nerve VI palsy, an exaggerated gag reflux, and a positive jaw jerk. The wound on his left ankle had healed. Normal strength and sensation were noted in all limbs, but muscle tone was increased. His patellar and ankle reflexes were "pathologically brisk", and he had bilateral positive Babinski signs. A CBC and comprehensive metabolic panel were within normal limits. Creatinine kinase was elevated at 1446 units/L. A lumbar puncture showed a protein level of 57 mg/dL in the cerebrospinal fluid, but no pleocytosis. Nerve conduction studies were essentially normal, except for the presence of afterpotentials following slow repetitive stimulation, suggesting peripheral nerve hyperexcitability. Needle electromyography studies were normal. Tetanus antibody levels were noted to be 2.78IU/mL (protective level defined as 0.01 IU/mL). The patient was diagnosed with generalized tetanus, and was admitted to the hospital where he was treated with baclofen, benzodiazepines, 5000 unites of human tetanus immune globulin, and a 7-day course of metronidazole despite the absence of an obvious wound site. At a 3-month follow-up visit, all of the patient's symptoms had resolved. The authors noted that the patient's antibody levels could reflect "either prior vaccination or immunostimulation from active tetanus". They also speculated that the patient's milder course of disease "may also have been related to his high level of antibody". Documents held by sender: None.
Age: 44.0
Sex: M
Vaccine: TTOX
Symptoms: Micturition urgency, Muscle spasms, Nerve conduction studies abnormal, Pain, Pollakiuria
Clinical narrative: A 44-year old male patient received an injection of TETANUS TOXOID (manufacturer and lot number not reported). Approximately 9 years post-vaccination, he was diagnosed with generalized tetanus. The patient had a history of multiple shrapnel and gunshot wounds from military service, and had no history of neuromuscular disease. He worked as a contractor and had sustained many nail-related injuries over the previous years, including an accident 6 months prior to presentation when he drove a nail into his left ankle with a nail gun. He removed the nail with a crowbar and did not seek medical care; he could not remember a more recent injury. Approximately 4 weeks prior to presentation, the patient developed an itching sensation in his right calf, which ascended to his right leg and began to involve his left leg. He subsequently developed muscle spasms in his right calf, which were intensely painful, sudden in onset, and up to 10 minutes duration. One week prior to presentation, the spasms began to occur more regularly. He developed trismus, dysphagia, and laryngospasms, with one episode resulting in several broken teeth. He had frequent, sudden urges to urinate, and lost 20 pounds unintentionally. Upon presentation, he had left cranial nerve VI palsy, an exaggerated gag reflux, and a positive jaw jerk. The wound on his left ankle had healed. Normal strength and sensation were noted in all limbs, but muscle tone was increased. His patellar and ankle reflexes were "pathologically brisk", and he had bilateral positive Babinski signs. A CBC and comprehensive metabolic panel were within normal limits. Creatinine kinase was elevated at 1446 units/L. A lumbar puncture showed a protein level of 57 mg/dL in the cerebrospinal fluid, but no pleocytosis. Nerve conduction studies were essentially normal, except for the presence of afterpotentials following slow repetitive stimulation, suggesting peripheral nerve hyperexcitability. Needle electromyography studies were normal. Tetanus antibody levels were noted to be 2.78IU/mL (protective level defined as 0.01 IU/mL). The patient was diagnosed with generalized tetanus, and was admitted to the hospital where he was treated with baclofen, benzodiazepines, 5000 unites of human tetanus immune globulin, and a 7-day course of metronidazole despite the absence of an obvious wound site. At a 3-month follow-up visit, all of the patient's symptoms had resolved. The authors noted that the patient's antibody levels could reflect "either prior vaccination or immunostimulation from active tetanus". They also speculated that the patient's milder course of disease "may also have been related to his high level of antibody". Documents held by sender: None.
Age: 44.0
Sex: M
Vaccine: TTOX
Symptoms: Pruritus, Reflex test normal, Tetanus, Tooth fracture, Trismus
Clinical narrative: A 44-year old male patient received an injection of TETANUS TOXOID (manufacturer and lot number not reported). Approximately 9 years post-vaccination, he was diagnosed with generalized tetanus. The patient had a history of multiple shrapnel and gunshot wounds from military service, and had no history of neuromuscular disease. He worked as a contractor and had sustained many nail-related injuries over the previous years, including an accident 6 months prior to presentation when he drove a nail into his left ankle with a nail gun. He removed the nail with a crowbar and did not seek medical care; he could not remember a more recent injury. Approximately 4 weeks prior to presentation, the patient developed an itching sensation in his right calf, which ascended to his right leg and began to involve his left leg. He subsequently developed muscle spasms in his right calf, which were intensely painful, sudden in onset, and up to 10 minutes duration. One week prior to presentation, the spasms began to occur more regularly. He developed trismus, dysphagia, and laryngospasms, with one episode resulting in several broken teeth. He had frequent, sudden urges to urinate, and lost 20 pounds unintentionally. Upon presentation, he had left cranial nerve VI palsy, an exaggerated gag reflux, and a positive jaw jerk. The wound on his left ankle had healed. Normal strength and sensation were noted in all limbs, but muscle tone was increased. His patellar and ankle reflexes were "pathologically brisk", and he had bilateral positive Babinski signs. A CBC and comprehensive metabolic panel were within normal limits. Creatinine kinase was elevated at 1446 units/L. A lumbar puncture showed a protein level of 57 mg/dL in the cerebrospinal fluid, but no pleocytosis. Nerve conduction studies were essentially normal, except for the presence of afterpotentials following slow repetitive stimulation, suggesting peripheral nerve hyperexcitability. Needle electromyography studies were normal. Tetanus antibody levels were noted to be 2.78IU/mL (protective level defined as 0.01 IU/mL). The patient was diagnosed with generalized tetanus, and was admitted to the hospital where he was treated with baclofen, benzodiazepines, 5000 unites of human tetanus immune globulin, and a 7-day course of metronidazole despite the absence of an obvious wound site. At a 3-month follow-up visit, all of the patient's symptoms had resolved. The authors noted that the patient's antibody levels could reflect "either prior vaccination or immunostimulation from active tetanus". They also speculated that the patient's milder course of disease "may also have been related to his high level of antibody". Documents held by sender: None.
Age: 44.0
Sex: M
Vaccine: TTOX
Symptoms: VIth nerve paralysis, Weight decreased
Clinical narrative: A 44-year old male patient received an injection of TETANUS TOXOID (manufacturer and lot number not reported). Approximately 9 years post-vaccination, he was diagnosed with generalized tetanus. The patient had a history of multiple shrapnel and gunshot wounds from military service, and had no history of neuromuscular disease. He worked as a contractor and had sustained many nail-related injuries over the previous years, including an accident 6 months prior to presentation when he drove a nail into his left ankle with a nail gun. He removed the nail with a crowbar and did not seek medical care; he could not remember a more recent injury. Approximately 4 weeks prior to presentation, the patient developed an itching sensation in his right calf, which ascended to his right leg and began to involve his left leg. He subsequently developed muscle spasms in his right calf, which were intensely painful, sudden in onset, and up to 10 minutes duration. One week prior to presentation, the spasms began to occur more regularly. He developed trismus, dysphagia, and laryngospasms, with one episode resulting in several broken teeth. He had frequent, sudden urges to urinate, and lost 20 pounds unintentionally. Upon presentation, he had left cranial nerve VI palsy, an exaggerated gag reflux, and a positive jaw jerk. The wound on his left ankle had healed. Normal strength and sensation were noted in all limbs, but muscle tone was increased. His patellar and ankle reflexes were "pathologically brisk", and he had bilateral positive Babinski signs. A CBC and comprehensive metabolic panel were within normal limits. Creatinine kinase was elevated at 1446 units/L. A lumbar puncture showed a protein level of 57 mg/dL in the cerebrospinal fluid, but no pleocytosis. Nerve conduction studies were essentially normal, except for the presence of afterpotentials following slow repetitive stimulation, suggesting peripheral nerve hyperexcitability. Needle electromyography studies were normal. Tetanus antibody levels were noted to be 2.78IU/mL (protective level defined as 0.01 IU/mL). The patient was diagnosed with generalized tetanus, and was admitted to the hospital where he was treated with baclofen, benzodiazepines, 5000 unites of human tetanus immune globulin, and a 7-day course of metronidazole despite the absence of an obvious wound site. At a 3-month follow-up visit, all of the patient's symptoms had resolved. The authors noted that the patient's antibody levels could reflect "either prior vaccination or immunostimulation from active tetanus". They also speculated that the patient's milder course of disease "may also have been related to his high level of antibody". Documents held by sender: None.
Age: 68.0
Sex: F
Vaccine: VARZOS
Symptoms: Dysphagia, Feeling abnormal
Clinical narrative: Pt. complained of difficulty in swallowing. A few minutes later stated slightly better/ not worse. A few minutes later stated not feeling good. Gave ZEPIPEN shots (IM) (total dose 0.6 mg). Called 911 paramedic showed within 5 minutes. Pt volunteered to go to ER.
Age: 1.59
Sex: F
Vaccine: HIBV, PNC
Symptoms: Injection site erythema, Injection site haematoma, Injection site induration, Injection site reaction, Injection site swelling
Clinical narrative: Large red circular welt at the site of injection measuring approximately 6cm in diameter.  The thigh swelled up, the welt felt very hard and hot to the touch.  At one point it resembled a blister.  It slowly appears to be fading.  3 weeks since the injection, it looks like a large bruise (though much lighter than it was originally) and still has some hardness to the touch. This was all a reaction to a Prevnar vaccine - her 4th dose with no prior reaction.
Age: 1.59
Sex: F
Vaccine: HIBV, PNC
Symptoms: Injection site urticaria, Injection site vesicles, Injection site warmth, No reaction on previous exposure to drug
Clinical narrative: Large red circular welt at the site of injection measuring approximately 6cm in diameter.  The thigh swelled up, the welt felt very hard and hot to the touch.  At one point it resembled a blister.  It slowly appears to be fading.  3 weeks since the injection, it looks like a large bruise (though much lighter than it was originally) and still has some hardness to the touch. This was all a reaction to a Prevnar vaccine - her 4th dose with no prior reaction.
Age: 0.17
Sex: M
Vaccine: RV5
Symptoms: Abdominal pain, Faeces discoloured, Haematochezia, Mucous stools
Clinical narrative: Severe abdominal pain, green mucousy stools preceded by blood in stools for weeks after given Rotavirus vaccine.
Age: 27.0
Sex: F
Vaccine: FLUN(H1N1), FLUX
Symptoms: Chills, Cough, Malaise, Oropharyngeal pain, Pain
Clinical narrative: fever, body aches, runny nose, cough, sore throat, chills that lasted about 4 days.  Symptoms subsided substantially after 2 days, but I did not feel completely well for nearly a week.
Age: 27.0
Sex: F
Vaccine: FLUN(H1N1), FLUX
Symptoms: Pyrexia, Rhinorrhoea
Clinical narrative: fever, body aches, runny nose, cough, sore throat, chills that lasted about 4 days.  Symptoms subsided substantially after 2 days, but I did not feel completely well for nearly a week.
Age: 20.0
Sex: F
Vaccine: HPV2
Symptoms: Colposcopy, Papilloma viral infection, Smear cervix abnormal
Clinical narrative: Informed of abnormal pap smear and that I had contracted HPV (was sent to indp. lab for testing). The only time this would have been able to have occured is during 2007 (~2 years after vaccination).
Age: 62.0
Sex: F
Vaccine: VARZOS
Symptoms: Condition aggravated, Fatigue, Headache, Heart rate increased, Heart rate irregular
Clinical narrative: muscle ache, head ache, erratic and rapid heart rate, fatigue, feeling sick, eyes bloodshot; usual minor maladies flared
Age: 62.0
Sex: F
Vaccine: VARZOS
Symptoms: Malaise, Myalgia, Ocular hyperaemia
Clinical narrative: muscle ache, head ache, erratic and rapid heart rate, fatigue, feeling sick, eyes bloodshot; usual minor maladies flared
Age: 1.01
Sex: F
Vaccine: MMR
Symptoms: Lethargy, Malaise, Pyrexia, Rash erythematous
Clinical narrative: Symptoms: Red spots on body, fever that peaked at 104.1 F, sick and lethargic baby. Treatment: Motrin and Tylenol as directed by doctor.
Age: 4.0
Sex: F
Vaccine: DTAPIPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling, Injection site warmth
Clinical narrative: Patient had very swollen, red and itchy leg that was hot to the touch at the injection site.
Age: 0.42
Sex: F
Vaccine: DTAPIPVHIB, PNC, RV5, RVX
Symptoms: Intestinal resection, Intussusception, Vomiting
Clinical narrative: Projectile vomiting, fever, severe dehydration.
Age: 0.42
Sex: F
Vaccine: DTAPIPVHIB, PNC, RV5, RVX
Symptoms: Appendicectomy, Blood test, Dehydration, Gastrointestinal disorder, Intussusception
Clinical narrative: Projectile vomiting, fever, severe dehydration.
Age: 0.42
Sex: F
Vaccine: DTAPIPVHIB, PNC, RV5, RVX
Symptoms: Pyrexia, Surgery, Ultrasound scan abnormal, Vomiting projectile, X-ray
Clinical narrative: Projectile vomiting, fever, severe dehydration.
Age: 5.0
Sex: M
Vaccine: DTAP, HIBV, IPV, MMR, VARCEL
Symptoms: Allergy test, Anaphylactic reaction, Blood immunoglobulin E increased, Lip swelling, Vomiting
Clinical narrative: after eating breakfast which included his routine fair of toast with jam and sunflower seed butter, he started throwing up and his lip started to swell. He had been eating sunflower seed butter for many months before that and he had no problems with it before. But just a few days after the immunizations he had a new Anaphylactic allergy to sunflower seeds. He had five (5) Immunization shots on Monday (Polio, DTP: [Diphtheria, Tetanus, Pertussis], Chicken Pox, Measles, Mumps, Ruebella) all in one day on May 11, 2009.
Age: 17.0
Sex: F
Vaccine: HPV4
Symptoms: Activities of daily living impaired, Anxiety, Chest discomfort, Dizziness, Eye pain
Clinical narrative: heart pounds, chest tightness, dizzyness, nausea.  I thought I was having panic attacks. experienced extreme fatigue and muscle weakness. Hospitalized 9/15/2009 because I was suicidal because I grew tired of living this way.  I was put on an anti-depressant (Lexapro), which has helped a little with anxiety (which I never had until after Garadasil adverse side effects). It is now 3/28/10, and I experience tingling sensation in my legs almost constantly and sometimes in my lower arms.  My chest is tight, and my muscles ache.  I still have symptoms that feel like panic attacks, but the worst would be the fatigue.  My eyes hurt, and pre-med major is difficult when so exhausted (let's not forget the difficulty of working full-time as well, as I am an independent student).  Since Gardasil, my life has become hell at a time when I should be in my prime.
Age: 17.0
Sex: F
Vaccine: HPV4
Symptoms: Fatigue, Laboratory test normal, Muscular weakness, Myalgia, Nausea
Clinical narrative: heart pounds, chest tightness, dizzyness, nausea.  I thought I was having panic attacks. experienced extreme fatigue and muscle weakness. Hospitalized 9/15/2009 because I was suicidal because I grew tired of living this way.  I was put on an anti-depressant (Lexapro), which has helped a little with anxiety (which I never had until after Garadasil adverse side effects). It is now 3/28/10, and I experience tingling sensation in my legs almost constantly and sometimes in my lower arms.  My chest is tight, and my muscles ache.  I still have symptoms that feel like panic attacks, but the worst would be the fatigue.  My eyes hurt, and pre-med major is difficult when so exhausted (let's not forget the difficulty of working full-time as well, as I am an independent student).  Since Gardasil, my life has become hell at a time when I should be in my prime.
Age: 17.0
Sex: F
Vaccine: HPV4
Symptoms: Palpitations, Panic attack, Paraesthesia, Suicidal ideation
Clinical narrative: heart pounds, chest tightness, dizzyness, nausea.  I thought I was having panic attacks. experienced extreme fatigue and muscle weakness. Hospitalized 9/15/2009 because I was suicidal because I grew tired of living this way.  I was put on an anti-depressant (Lexapro), which has helped a little with anxiety (which I never had until after Garadasil adverse side effects). It is now 3/28/10, and I experience tingling sensation in my legs almost constantly and sometimes in my lower arms.  My chest is tight, and my muscles ache.  I still have symptoms that feel like panic attacks, but the worst would be the fatigue.  My eyes hurt, and pre-med major is difficult when so exhausted (let's not forget the difficulty of working full-time as well, as I am an independent student).  Since Gardasil, my life has become hell at a time when I should be in my prime.
Age: 1.08
Sex: M
Vaccine: MMRV
Symptoms: Aphasia, Autism, Decreased eye contact, Diagnostic procedure, Irritability
Clinical narrative: fever >101.0 off and on for 5 days, fussy vs. lethargic, developed severe cold symptoms with hacking cough and excessive mucous, fever treated with chidrens acetememophen with decreased temperature, cold symptoms persisted x 3 weeks, then withdrawn affect was noted post illness, lack of crying, no eye contact, no pain response, loss of words, dx of autism 6 mos later.
Age: 1.08
Sex: M
Vaccine: MMRV
Symptoms: Lethargy, Mood altered, Nasopharyngitis, Productive cough, Pyrexia
Clinical narrative: fever >101.0 off and on for 5 days, fussy vs. lethargic, developed severe cold symptoms with hacking cough and excessive mucous, fever treated with chidrens acetememophen with decreased temperature, cold symptoms persisted x 3 weeks, then withdrawn affect was noted post illness, lack of crying, no eye contact, no pain response, loss of words, dx of autism 6 mos later.
Age: 1.08
Sex: M
Vaccine: MMRV
Symptoms: Social avoidant behaviour, Unresponsive to stimuli
Clinical narrative: fever >101.0 off and on for 5 days, fussy vs. lethargic, developed severe cold symptoms with hacking cough and excessive mucous, fever treated with chidrens acetememophen with decreased temperature, cold symptoms persisted x 3 weeks, then withdrawn affect was noted post illness, lack of crying, no eye contact, no pain response, loss of words, dx of autism 6 mos later.