Age: 13.0
Sex: F
Vaccine: HPV4
Symptoms: Gastrointestinal disorder, Gluten sensitivity, Headache, Loss of personal independence in daily activities, Memory impairment
Clinical narrative: chonic and severe headaches/occipital neuralgia/neurological injury/constant migraines; abdominal pain/gastrointestinal symptoms/gastritis/nausea/bloating; slow speech; gluten sensitivity/chronic constipation/brain fog/joint pain/abdominal pain/nausea/bloating/chronic fatigue; alopecia; muscle spasms; rheumatologic disorder/autoimmune injury; ovarian failure/amenorrhea/memory problems; autonomic injury; muscle weakness; constant joint and body pain; dizziness; constellation of adverse symptoms, complications, injuries, and other adverse events; Information has been received from a lawyer regarding a case in litigation, concerning a female patient (pt) of unknown age. The pt's medical history, concurrent conditions, and concomitant medications were not provided. On unknown dates (when she was 13-years old), following her doctors' recommendations, the pt was inoculated with the three doses of Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) injection as prevention of cervical cancer (dose, route of administration, anatomical location, lot number, and expiration date were not provided). On an unknown date, following her vaccinations, the patient began to experience chronic and severe headaches, which became progressively worse and longer in duration, abdominal pain, gastrointestinal symptoms, gastritis, amenorrhea, constant joint and body pain, dizziness, brain fog, slow speech, memory problems, nausea, bloating, alopecia, gluten sensitivity and chronic constipation. As a result of her post Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) symptoms, the pt has been unable to engage in activities that a normal young person would enjoy. She was in constant pain. The pt enjoyed playing varsity and club volleyball but was now unable to participate in any sports and/or physical activity due to extreme joint pain, muscle spasms and muscle weakness, body pain, chronic fatigue, and constant migraines. As the months progressed, so did the pt's symptoms. She was seen by multiple physicians and specialists, including a neurologist, gastroenterologist, pediatric surgeon, and a pain management specialist for her complaints. One doctor suggested that she be checked for rheumatologic disorders. At one point, her symptoms were so severe she was taken to the emergency room and admitted to the hospital. The pt suspected her symptoms were caused by the vaccine. Based upon her chronic and severe symptoms she was diagnosed with various medical conditions, including gastrointestinal dysfunction, amenorrhea, ovarian failure, chronic headaches, and chronic fatigue, she has been diagnosed with various medical conditions, including but not limited to, occipital neuralgia and chronic headache disorder. In addition, the pt contended that her Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological injuries, including but not limited to occipital neuralgia, ovarian failure, chronic headaches, gastrointestinal dysfunction, amenorrhea, constant joint and body pain, alopecia, and gluten sensitivity, as well as a constellation of adverse events symptoms, complications, injuries, and other adverse events, many of which were alleged herein and all of which were caused by Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) or otherwise linked to Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL). The outcome of the adverse events was unknown, and it was considered all the events to be related to Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL).  Upon internal review the event autonomic neuropathy was considered to be medically significantly.