Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Electrocardiogram, Gluten sensitivity, Herpes simplex, Hypersensitivity, Lip swelling
Clinical narrative: lymph nodes in her legs were swollen; lymph nodes in her legs were painful; severe gluten allergy; staff tried 5 to 6 times in both arms trying to get blood; difficulty breathing/couldn't breathe; a herpes outbreak on her buttocks/herpes simplex outbreak/7 quarter size areas on her left butt and down her left leg; a rash completely covering her hands, head and ears; hand were itching/head was itching/ears were itching; loses 3-4 lbs after each episode and has lost a total of 12 pounds; an upset stomach; four other allergy attacks/ allergic reaction during a barbeque; urticaria/ a rash from the bottom of her breasts to her nose; lip swelling; This is a spontaneous report from a contactable consumer (patient). This 53-year-old female patient received  the second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: ER8727; Expiration Date: 31Jul2021), via an unspecified route of administration in the left arm on 20Mar2021 (at the age of 53-year-old) as single dose for COVID-19 immunization. The patient provided the following for her medical history described: As a teenager, she was very allergic to everything- foods, vegetables, apples, tomatoes, avocado, raw almonds and pollen: Her throat would swell, and her face would swell up but would take cortisone and it would be good the next day. After her pregnancies, her allergies subsided and were well managed for 15 years. In the past, she was taking RECTODELT for her allergies to food and normally it would help with that. It worked quick, within 15 minutes. She also has ongoing herpes simplex and sometimes it's on her butt. Concomitant medications included fexofenadine hydrochloride (ALLEGRA) taken for hypersensitivity, start and stop date were not reported; dexamethasone (manufacturer unknown) taken for malaise; naproxen (manufacturer unknown) taken for pain; naproxen sodium (ALEVE) taken for an unspecified indication. The patient previously received Flu vaccination in Aug2020. The patient previously received the first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: EN6205; Expiration Date: 30Jun2021), via an unspecified route of administration in the right arm on 27Feb2021 (at the age of 53-year-old) as single dose for COVID-19 immunization. The patient reported that she received her second Covid-19 vaccine on 20Mar2021, and she didn't have a reaction right away. On 04May2021 she had an allergic reaction completely different than what she's used to. She explained that she had a BBQ (barbeque) and she ate vegetables and had half a glass of rose wine, and she went to bed around 11:00PM on 04May2021. On 04May2021 at night she woke up in the middle of the night with difficulty breathing, an upset stomach, and a rash completely covering her hands, head and ears. On 04May2021, she took some cortisone, RECTODELT, a 100mg prednisone suppository, but it didn't help. She has a doctor friend who had given her some medications. Her doctor friend had given her an antihistamine liquid, CELESTAMINE N 30ml, and a cortisone liquid, SENISTIO 20ml, and those two medications combined helped her symptoms. The next day it was better. On 06May2021 she couldn't breathe so her doctor friend told her to go to the emergency department (ED) so she went to the emergency room on 06May2021 in the middle of the night. She also did have an outbreak when she went to the emergency room. She had it so very bad. She had about 7 quarter size areas on her left butt and down her left leg and the lymph nodes in her legs were swollen and painful. The emergency room checked her blood pressure and it was fine, they checked her oxygen level and that was fine, they did an EKG and that was ok, and they did blood work and that was ok too. In the emergency department, she did have an IV and they gave her Cortisone in her IV. She had the IV in her right arm and when she received the Cortisone her arm was getting warm and then she felt flushed through her whole body. It was really strange, and she was super scared. Also while she was in the emergency room, the emergency room staff tried 5 to 6 times in both arms trying to get blood and he tried to go in her lower arm and she finally asked that someone else try to get blood. They discharged her and told her to follow up with her primary care physician (PCP) and an allergy doctor. Since 04May2021, she has had four other allergy attacks. She loses 3-4 lbs after each episode and has lost a total of 12 pounds. She reported she saw her primary care doctor on 18May2021 and received a prescription for steroids for a herpes outbreak on her buttocks and went down her legs. During her doctor visit on 18May2021, she had allergy testing done: She is allergic to almost everything, and she can only eat chicken and rice because she now has a severe gluten allergy. She was told to take 2 Allegra per day for 10 days and was given 1mg dexamethasone to take if she feels really bad. When she saw her family doctor, her doctor asked her if she had been in a fight because her arms looked so bad from all the needle sticks trying to get blood. It was very painful. She doesn't think the allergic reaction was related to the emergency room staff not being able to get blood from her. And she does drink a lot so she doesn't get dehydrated. She had some allergy tests and those came back that she's allergic to almost everything. The doctor also prescribed Valacyclovir HCl 1gm tablet for the herpes simplex. Her doctor told her to take it for another week and then stop taking it and then start again if she has another outbreak. The Acyclovir she was taking wasn't working. It was Acyclovir 800mg in a pharmacy bottle (Discard by date: 14Aug2021). Her gynecologist gave her Naproxen to take for pain. She does a lot of yoga and when her joints are hurting she takes Aleve. She did take Aleve on the day of her first Covid 19 vaccine and she drank a lot of water and a lot of Gatorade. The patient reported that the itchy head, hands, and ears happened 3 or 4 more times. She's thinking this could be related to the Covid-19 vaccine, that the Covid-19 vaccine triggered her allergies. This past Monday/Tuesday (May2021) she had her most recent allergic attack (she is not sure if it was from eating potato chips or just taking one Allegra that day), she had difficulty breathing, lip swelling, urticaria/ a rash from the bottom of her breasts to her nose. She had an EpiPen nearby and she took an 100mg suppository of prednisone. Her doctor told her to take 2 Allegras everyday indefinitely. She is feeling better today and was able to go to a yoga class- but still has the rash. She saw her PCP yesterday (25May2021) and got a prescription for valacyclovir, she is to take it for 7 days and then start again if it flares up again. She is getting an inhaler today for if she has difficulty breathing again due to an allergic reaction. Her doctor thinks this may all be caused by a histamine intolerance from the shot, her other HCPs do not believe its vaccine related.  Her doctor also said that it could be due to a bad mosquito bite that she got two weeks before her first allergic reaction or due to a teeth whitening procedure that she had issues that she also received before the allergic reactions started. The clinical outcome of the events " urticaria/ a rash from the bottom of her breasts to her nose" was not resolved, and the outcome of the events, difficulty breathing/couldn't breathe, "a herpes outbreak on her buttocks/herpes simplex outbreak/7 quarter size areas on her left butt and down her left leg", "four other allergy attacks/ allergic reaction during a barbeque", an upset stomach, "a rash completely covering her hands, head and ears", loses 3-4 lbs after each episode and has lost a total of 12 pounds, lip swelling, hand were itching/head was itching/ears were itching, lymph nodes in her legs were swollen, lymph nodes in her legs were painful, severe gluten allergy and "staff tried 5 to 6 times in both arms trying to get blood" were unknown.