Age: 83.0
Sex: F
Vaccine: COVID19
Symptoms: Constipation, Micrographia, Parkinson's disease, Tremor
Clinical narrative: symptoms could be Parkinson's; right hand started trembling when at rest but stops when she looks at it/tremor; constipated; handwriting has also gone really really small; This spontaneous case was reported by a nurse and describes the occurrence of PARKINSON'S DISEASE (symptoms could be Parkinson's), TREMOR (right hand started trembling when at rest but stops when she looks at it/tremor) and MICROGRAPHIA (handwriting has also gone really really small) in an 83-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 022B21A, 002C21A and 06(?)1H21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Diabetes (which is controlled by diet) and Hypertension (She has been taking Atenolol 25mg 2x a day for the hypertension for many years now.). Concomitant products included ATENOLOL for Hypertension.   On 21-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 20-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In June 2021, the patient experienced PARKINSON'S DISEASE (symptoms could be Parkinson's) (seriousness criterion medically significant), TREMOR (right hand started trembling when at rest but stops when she looks at it/tremor) (seriousness criterion medically significant), CONSTIPATION (constipated) and MICROGRAPHIA (handwriting has also gone really really small) (seriousness criterion medically significant). At the time of the report, PARKINSON'S DISEASE (symptoms could be Parkinson's), CONSTIPATION (constipated) and MICROGRAPHIA (handwriting has also gone really really small) outcome was unknown and TREMOR (right hand started trembling when at rest but stops when she looks at it/tremor) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   She did not have any allergies. she had not had any Covid-19 diagnosis pre or post vaccination. Treatment medication was not reported.  Company Comment: This spontaneous case concerns an 83-year-old, female patient, with a concurrent condition of diabetes, who experienced the unexpected, medically significant serious events of Parkinson's disease, Tremor, & Micrographia a little more than 2 weeks after receiving her 2nd dose of mRNA-1273 vaccine. She reportedly noticed her right hand started trembling at rest that stops spontaneously, and her handwriting became noticeably smaller. She also became constipated. Consultation with an internist 6 months ago was reportedly done and a follow-up was scheduled. Event outcome of tremor was ongoing. Her age and concurrent condition of diabetes remain as confounders to the event tremor. The benefit-risk relationship of mRNA-1273 is not affected by this report. Events' seriousness assessed based on medical judgement and the available information.; Sender's Comments: This spontaneous case concerns an 83-year-old, female patient, with a concurrent condition of diabetes, who experienced the unexpected, medically significant serious events of Parkinson's disease, Tremor, & Micrographia a little more than 2 weeks after receiving her 2nd dose of mRNA-1273 vaccine. She reportedly noticed her right hand started trembling at rest that stops spontaneously, and her handwriting became noticeably smaller. She also became constipated. Consultation with an internist 6 months ago was reportedly done and a follow-up was scheduled. Event outcome of tremor was ongoing. Her age and concurrent condition of diabetes remain as confounders to the event tremor. The benefit-risk relationship of mRNA-1273 is not affected by this report. Events' seriousness assessed based on medical judgement and the available information.