Age: 73.0
Sex: M
Vaccine: COVID19
Symptoms: Bronchial obstruction, Bronchial oedema, Dyspnoea, Fatigue, Pain in extremity
Clinical narrative: Feeling like bronchial tubes swelled up; Feeling like bronchial tubes closed; Unable to breathe/difficulty breathing; Could not hold head up; Very fatigued; arm was sore; This spontaneous case was reported by a consumer and describes the occurrence of BRONCHIAL OEDEMA (Feeling like bronchial tubes swelled up) and BRONCHIAL OBSTRUCTION (Feeling like bronchial tubes closed) in a 73-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 038C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 (first week of Jan2021) in January 2021 and Knee replacement (On physical therapy 3 times a week) on 14-May-2021. Concurrent medical conditions included Shellfish allergy, Grass allergy and Asthma. Concomitant products included FLUTICASONE PROPIONATE, SALMETEROL XINAFOATE (ADVAIR), MONTELUKAST, SALBUTAMOL (ALBUTEROL HFA) and HYDROCODONE for an unknown indication.    On 07-Jun-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 07-Jun-2021, the patient experienced PAIN IN EXTREMITY (arm was sore). On 08-Jun-2021, the patient experienced BRONCHIAL OEDEMA (Feeling like bronchial tubes swelled up) (seriousness criterion medically significant), BRONCHIAL OBSTRUCTION (Feeling like bronchial tubes closed) (seriousness criterion medically significant), DYSPNOEA (Unable to breathe/difficulty breathing), POSTURE ABNORMAL (Could not hold head up) and FATIGUE (Very fatigued). The patient was treated with SALBUTAMOL (ALBUTEROL HFA) for Breathing difficult, at a dose of ~10 puffs. On 09-Jun-2021, BRONCHIAL OEDEMA (Feeling like bronchial tubes swelled up), DYSPNOEA (Unable to breathe/difficulty breathing), POSTURE ABNORMAL (Could not hold head up) and FATIGUE (Very fatigued) had resolved, BRONCHIAL OBSTRUCTION (Feeling like bronchial tubes closed) outcome was unknown. On 10-Jun-2021, PAIN IN EXTREMITY (arm was sore) had resolved.        mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   This case concerns a 73-year-old male with serious unexpected events of bronchial edema and bronchial obstruction, and nonserious dyspnea, posture abnormal, pain in extremity, and fatigue. Event latency 2 days after first dose mRNA-1273. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.; Sender's Comments: This case concerns a 73-year-old male with serious unexpected events of bronchial edema and bronchial obstruction, and nonserious dyspnea, posture abnormal, pain in extremity, and fatigue. Event latency 2 days after first dose mRNA-1273. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.