Sex: F
Vaccine: COVID19
Symptoms: Myelopathy, Pain in extremity, Paraesthesia, SARS-CoV-2 test
Clinical narrative: COVID myelopathy; felt that her walking was off; feeling numbness of her right leg going up to her upper abdomen/ decreased sensation on her right side up to a mid-thoracic sensory level; COVID myelopathy/ leftsided cervical myelopathy; left arm pain and discomfort; left arm pain and discomfort; tingling sensation in her third, fourth, and fifth digits on her left hand; This is a spontaneous report from a non-contactable Pharmacist. A 60-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, LOT/Batch number and expiration date unknown) via unspecified route of administration on 21Jan2021 at unspecified age at single dose for COVID-19 immunisation. Patient was not pregnant at the time of events onset and at time of vaccination. Medical history included mitral valve atresia (MVA) and back pain. Patient has known allergies penicillin. The patient presented to office on 25Feb2021 with left arm pain and discomfort that started three weeks ago on 21Jan2021 and had resolved but left her with tingling sensation in her third, fourth, and fifth digits on her left hand, symptoms started three weeks ago, hours after getting her COVID-19 vaccine. About a week and a half ago in Feb2021 she began feeling numbness of her right leg going up to her upper abdomen with progressively worsening symptoms that had stabilized in the past several days. She also felt that her walking was off but cannot quite describe how or when it started. Exam notable for leftsided cervical myelopathy and decreased sensation on her right side up to a mid-thoracic sensory level. Of note she has a first cousin on her fathers side with multiple sclerosis and a more distant cousin on her mother's side with multiple sclerosis. Father with Parkinson's disease. COVID-19 biofire came back positive. In light of this, COVID myelopathy was (missing information). Adverse event COVID myelopathy start date was reported as 21Jan2021. It was reported that the events resulted in doctor or other healthcare professional office/clinic visit, hospitalization. It was unknown if there was COVID prior vaccination. COVID was tested post vaccination. Outcome of event left arm pain and discomfort was recovered with sequel, of the other events was unknown.  No follow-up attempts are possible, Information about batch/lot number cannot be obtained. No further information is expected.; Sender's Comments: Based on a temporal association, the causal association between the reported events and the suspect drug cannot be totally excluded. Patient's risk factor (family history of multiple sclerosis) can also be assessed as possibly contributory to the events. Case to be reassessed if follow-up information is received.  The impact of this report on the benefit/risk profile of the Pfizer product is evaluated a part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events.  Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory authorities, Ethics committees, and Investigators, as appropriate.