Age: 55.0
Sex: M
Vaccine: COVID19
Symptoms: Diplopia, Discomfort, Dysarthria, Eczema, Facial paralysis
Clinical narrative: Neurological symptoms; slurred speech; possible myasthenia gravis; drooping right eye lid/ then progressively had whole right side of face drooped; having issues with his left side; double vision; his eczema was aggravated; This spontaneous case was reported by a pharmacist and describes the occurrence of MYASTHENIA GRAVIS (possible myasthenia gravis) and FACIAL PARALYSIS (drooping right eye lid/ then progressively had whole right side of face drooped) in a 55-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 26-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 28-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In July 2021, the patient experienced ECZEMA (his eczema was aggravated). In September 2021, the patient experienced DISCOMFORT (having issues with his left side) and DIPLOPIA (double vision). On an unknown date, the patient experienced MYASTHENIA GRAVIS (possible myasthenia gravis) (seriousness criterion medically significant), FACIAL PARALYSIS (drooping right eye lid/ then progressively had whole right side of face drooped) (seriousness criterion medically significant), NEUROLOGICAL SYMPTOM (Neurological symptoms) and DYSARTHRIA (slurred speech). The patient was treated with PYRIDOSTIGMINE BROMIDE at an unspecified dose and frequency and PREDNISONE at an unspecified dose and frequency. At the time of the report, MYASTHENIA GRAVIS (possible myasthenia gravis), ECZEMA (his eczema was aggravated), NEUROLOGICAL SYMPTOM (Neurological symptoms), DISCOMFORT (having issues with his left side) and DIPLOPIA (double vision) outcome was unknown, FACIAL PARALYSIS (drooping right eye lid/ then progressively had whole right side of face drooped) had not resolved and DYSARTHRIA (slurred speech) was resolving.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   Concomitant product was not provided by the reporter.  Patient reported that he experienced Eczema, he visited to dermatologist 10 weeks ago due to eczema was aggravated. Six weeks ago he experienced neurological symptoms drooping eye lid, progressively had whole right side of face drooped and slurred speech. He experiencing issues with his left side, eyelid droop was intermittently better, then worse, double vision. His slurred speech had improved.   Patient done with on 07-Sep-2021 laboratory test computed tomography scan of the chest/neck area to check his thymus results were not provided.  Company comment: This case concerns a 55-year-old male patient with no reported medical history, who experienced the unexpected event of nyastenia gravis-like reaction and facial paralysis. The events occurred on an unknown date after the second dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was unknown as information pertaining to the first dose and date of second dose were not disclosed. Causality for the reported event was not provided by the reporter. The benefit-risk relationship of mRNA-1273 (Moderna COVID-19 Vaccine) is not affected by this report.; Sender's Comments: This case concerns a 55-year-old male patient with no reported medical history, who experienced the unexpected event of nyastenia gravis-like reaction and facial paralysis. The events occurred on an unknown date after the second dose of mRNA-1273 (Moderna COVID-19 Vaccine). The rechallenge was unknown as information pertaining to the first dose and date of second dose were not disclosed. Causality for the reported event was not provided by the reporter. The benefit-risk relationship of mRNA-1273 (Moderna COVID-19 Vaccine) is not affected by this report.