Age: 72.0
Sex: F
Vaccine: COVID19
Symptoms: Condition aggravated, Myalgia, Neuropathy peripheral, Product administered at inappropriate site
Clinical narrative: injection in much higher than they've had with prior injections.; neuropathy in the arm/some pain in the muscle/soreness; neuropathy in the arm/some pain in the muscle/soreness; some pain in the muscle/soreness; This spontaneous case was reported by a patient and describes the occurrence of CONDITION AGGRAVATED (neuropathy in the arm/some pain in the muscle/soreness) and NEUROPATHY PERIPHERAL (neuropathy in the arm/some pain in the muscle/soreness) in a 72-year-old female patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Mastectomy (they removed 15 lymph nodes.). Previously administered products included for Product used for unknown indication: pfizer (It just laid the patient out for a month. She added she felt miserable (with Pfizer).) in 2023. Past adverse reactions to the above products included Adverse reaction with pfizer. Concurrent medical conditions included Neuropathy and Neuromuscular disorder NOS.    On 17-Oct-2024, the patient received first dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (unknown route) 1 dosage form. In 2024, the patient experienced CONDITION AGGRAVATED (neuropathy in the arm/some pain in the muscle/soreness) (seriousness criterion medically significant), NEUROPATHY PERIPHERAL (neuropathy in the arm/some pain in the muscle/soreness) (seriousness criterion medically significant) and MYALGIA (some pain in the muscle/soreness). On 17-Oct-2024,  after starting mRNA-1273.712 (SPIKEVAX 2024-2025 PFS), the patient experienced PRODUCT ADMINISTERED AT INAPPROPRIATE SITE (injection in much higher than they've had with prior injections.). At the time of the report, CONDITION AGGRAVATED (neuropathy in the arm/some pain in the muscle/soreness), NEUROPATHY PERIPHERAL (neuropathy in the arm/some pain in the muscle/soreness), MYALGIA (some pain in the muscle/soreness) and PRODUCT ADMINISTERED AT INAPPROPRIATE SITE (injection in much higher than they've had with prior injections.) outcome was unknown.        The action taken with mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Unknown) was unknown.   For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication was reported. She had nerve damage under her left armpit and in her left upper arm that's causing neuropathy in the arm down to her hand. She had neuromuscular disease that can cause the same thing. She had nerve damage was from a mastectomy where they removed 15 lymph nodes. She had pain but it's got really severe in the last couple of weeks and at first she thought it's just getting worse but then she thought maybe it was related to the vaccine (given the time frame). She noted that these side effects were present in the opposite arm of which she was vaccinated. She also added that in the past she didn't have a lot of trouble with prior Moderna vaccines but last fall got the Pfizer and it just laid the patient out for a month. She also reported some pain in the muscle/soreness post administration because it seemed like that druggist put the injection in much higher than they've had with prior injections. Reporter causality was not reported. No treatment medication was reported.   This case was linked to US-MODERNATX, INC.-MOD-2024-776607 (E2B Linked Report).; Reporter's Comments: Patient's concurrent neuromuscular disease and medical history of nerve damage was from a mastectomy could be confounding factors.The benefit-risk relationship of the product is not affected by this report.; Sender's Comments:  US-MODERNATX, INC.-MOD-2024-776607:Same reporter different patient