Age: 40.0
Sex: F
Vaccine: COVID19
Symptoms: Condition aggravated, Electrocardiogram, Feeling abnormal, Sinus rhythm, Ventricular extrasystoles
Clinical narrative: felt bad for 36 hours after second dose, she felt similar on the booster dose; I began experiencing intermittent PVC's [premature ventricular contractions] that have been progressively getting worse; I began experiencing intermittent PVC's [premature ventricular contractions] that have been progressively getting worse; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 40 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 21Dec2021 16:00 (Lot number: FE3594, Expiration Date: 28Feb2022) at the age of 40 years as dose 3 (booster), 0.3 ml single for covid-19 immunisation. Relevant medical history included: "headaches" (unspecified if ongoing); "body aches" (unspecified if ongoing), notes: body aches; "horrible, terrible heartburn" (unspecified if ongoing), notes: horrible, terrible heartburn; "She had PVCs before but never this bad" (unspecified if ongoing). Concomitant medication(s) included: TYLENOL taken for headache, pain; NEXIUM [ESOMEPRAZOLE SODIUM] taken for dyspepsia. Vaccination history included: Bnt162b2 (Dose 01, Lot: EN6199, Expiration: nknown), administration date: 10Mar2021, when the patient was 39 years old, for COVID-19 immunization, reaction(s): "First two doses made her arm kind of sore"; Bnt162b2 (Dose 02, Lot: EP7533, Expiration: unknown), administration date: 20Apr2021, when the patient was 40 years old, for COVID-19 immunization, reaction(s): "felt bad for 36 hours after second dose", "First two doses made her arm kind of sore". The following information was reported: CONDITION AGGRAVATED (non-serious), VENTRICULAR EXTRASYSTOLES (non-serious) all with onset Jan2022, outcome "not recovered" and all described as "I began experiencing intermittent PVC's [premature ventricular contractions] that have been progressively getting worse"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "felt bad for 36 hours after second dose, she felt similar on the booster dose". The events "i began experiencing intermittent pvc's [premature ventricular contractions] that have been progressively getting worse", "i began experiencing intermittent pvc's [premature ventricular contractions] that have been progressively getting worse" and "felt bad for 36 hours after second dose, she felt similar on the booster dose" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: On 3-4/Jan2022 I began experiencing intermittent PVC's [premature ventricular contractions] that have been progressively getting worse. I been to the doctor and everything came back normal. She had an appointment with cardiologist next week (on 02Feb2022). It was reported that a review of the Prescribing Information for the Pfizer-BioNTech COVID-19 vaccine for 12 years and older formulation (purple cap)  did not find information regarding premature ventricular contractions (PVC's). As the Prescribing Information does not include all adverse reactions that have been reported or that may occur, please consult with your doctor/healthcare provider about what you have experienced/are experiencing. Because your doctor/healthcare provider was most familiar with your medical condition, clinical history, how your treatment has been conducted and any relevant information to your specific case, your doctor/healthcare provider is in the best position to advise you about the appropriate action to take. In regards to heart conditions, myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining outside the heart) have occurred in some people who have received Comirnaty (COVID-19 Vaccine, mRNA) or the Pfizer-BioNTech COVID-19 Vaccine. In most of these people, symptoms began within a few days following receipt of the second dose of vaccine. The chance of having this occur was very low. According to the withheld Centers for Disease Control and Prevention (or CDC), reports of myocarditis and pericarditis were rare given the number of doses administered. Patients have typically quickly improved with treatment and rest. The patient taking covid 19 vaccine (Verbatim) as prevention, did not want to catch covid. She went to the doctor and had an EKG, or ECG, nothing abnormal was seen and sinus rhythm was normal. She caught the PVCs on her apple watch, and she showed the doctor that it was kind of adding an extra beat. They have gotten progressively worse over last two weeks. Prior vaccinations (within 4 weeks) was none. . Follow-up attempts are completed. No further information is expected.