Age: 55.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Injection site erythema, Injection site paraesthesia, Injection site pruritus, Injection site urticaria, Limb discomfort
Clinical narrative: Received a Pfizer Covid 19 vaccine at 11:20 AM on Feb. 3, 2021, and in less than 1 minute developed an itchy hive at the injection site with raised redness that was blotchy on my right upper arm that spread to my upper chest up my neck. My entire right arm felt itchy and tickling that spread to my respiratory system, in both lungs, windpipe, tongue, throat, and ears. My mouth, throat, and tongue felt itchy/tickling (like tons of mosquito bites) and swollen with my voice becoming hoarse and tight and I felt short of breath. I found a registered nurse (RN) to help me and they brought me back to a room to check my blood pressure which was 240/130 and ranged from SBP 210 - 250 combined with a DBP 110 ? 140 in both arms with either a large or small cuff. Several blood pressures taken. The RN called for security to take me to the Emergency Room (ER) since my blood pressure was sustained at a very elevated level. Before I was brought up to the ER, I started having what felt like was arrows or sharp knives being pierced through my lungs (excruciating pain) as I tried to take and exhale a breath, I couldn?t breathe. The itching and piercing knife-like arrows started in my entire chest then isolated into my left chest, then my right chest, moving back and forth to different sides of the chest or the whole chest in what seemed like a random sequence. In addition to these symptoms, I had knife-like pain piercing throughout my abdomen non-stop which made me nauseated.  Shortly after arrival to the ER, I developed crushing chest pain (heart) and my left side of my face, left arm and left sole of my foot felt heavy and numb. I also felt a rush of fast hard painful heartbeats, an arrhythmia, at the same time. ER staff came back quickly in my room and asked me how I was feeling and I reported the crushing chest (heart) pain, the fast, hard painful heartbeats, an arrhythmia, and the left side of my face, left arm and left sole of my foot feeling heavy and numb (concerned about a possible stroke); and the ER doctor said I had just ?flipped? my t wave and had a run of supraventricular tachycardia (SVT). I was given an Aspirin to chew and Morphine Sulfate IV to help ease the pain on my myocardium which the ER physician believed was being irritated by the sustained high blood pressure and anaphylaxis reaction from the Pfizer Covid 19 shot. I was diaphoretic from scalp to toe with a nurse commenting that the vinyl mattress of the ER stretcher was soaked from my diaphoresis.  The ER physician said I was her 5th patient with an anaphylactic reaction to the Covid 19 vaccine. My blood pressure was responsive to the Morphine Sulfate IV bringing it to 200/101 but this is not my normal blood pressure measuring from SBP100-120 over DBP 60/80. My telemetry was showing constant ventricular arrhythmias to include multifocal premature ventricular contractions (PVCs) (singles, couplets, bigeminy, trigeminy, SVT, Ventricular Tachycardia) creating terrible chest (heart) pain. I received a dose of benedryl and solumedrol and Pepcid via IV in the Emergency Room while I was there for 7 hours. I was admitted to the medical center for worsening ECG changes (constant ventricular arrhythmias and a flipped t wave), chest pain (cardiac), diaphoresis, dyspnea which is shortness of breath at rest, and exhaustion (fatigue); and the ongoing anaphylaxis signs and symptoms.  I was started on metoprolol 12.5 mg BID for the ongoing cardiac chest pain and arrythmias, dyspnea, diaphoresis, and ongoing extreme blood pressure while observed during my hospitalization.   I was discharged the next day about 4:30 pm despite that I had unresolved intense severity of signs and symptoms (cardiac and anaphylaxis) that continued as stated above notwithstanding a 12 Lead ECG taken approximately 1 pm since I had an episode of extreme chest (heart) pain, with sustained elevated systolic and diastolic blood pressures, frequent multifocal PVCs to include via telemetry (couplets, bigeminy, trigeminy, and SVT), a flipped t wave (noting that these arrhythmias are aberrant and symptomatic with diaphoresis, heart pain, dyspnea at rest, left sided facial, arm, and sole of foot numbness/heaviness and a pounding headache).  My husband drove me to my Primary Care Physician the following day on February 5,  since I continued to have the same frequency and severity of symptoms and signs (extreme aberrant elevated blood pressure, diaphoresis, multifocal PVCs, chest (heart) pain, dyspnea at rest, fatigue, nausea, anaphylaxis signs and symptoms (to also include tongue swelling and hoarse voice/tight), left sided facial, arm, and sole of foot heaviness and numbness intermittently etc.). My Primary Care Doctor told me he wanted me taken by ambulance immediately to the hospital Emergency Room where I was found to be in persistent, frequent cardiac ventricular arrhythmias to include multifocal PVCs, bigeminy, trigeminy, couplets, and SVT; sustained elevated systolic (200 plus) and diastolic (100 plus) blood pressure; diaphoresis scalp to the sole of my foot; all the same anaphylaxis symptoms to include swelling of the back of my left tongue; difficulty taking a breath because my respirations were very tight with arrow-like pain piercing through my lungs; tickling and itching from my lungs up through my windpipe, my mouth and through my ears; knife-like pain piercing through my abdomen with nausea; hot razor blade-like pain on all of my skin, a pounding headache, etc. as reported above since the signs and symptoms never ceased at the first Emergency Room with subsequent hospitalization. I was treated with Solumedrol 120 mg, Pepcid, and Benedryl IV; and continued with metoprolol for the cardiac arrhythmias and extreme elevated blood pressure and anaphylaxis and was admitted to the hospital for a second time.  I was prescribed Prednisone 20 mg each day, Pepcid 20 mg BID; and Benedryl and other antihistamines every 6 hours, and I take all as prescribed.   My Metoprolol was increased in dose to 50 mg twice a day and to date, I am still on this medication since I continue to have ventricular arrhythmias.  I am a critical care and oncology RN and I know when my heart beats are not perfusing; and I have had a cardiac ultrasound which showed frequent multi-focal premature ventricular contractions. I feel these painful beats as they occur. There are changes now on my 12-Lead ECG and echo cardiac ultrasound at rest and I am symptomatic with palpitations, high blood pressure despite taking metoprolol and now Magnesium Chloride, shortness of breath that increases with activity; diaphoresis, exhaustion that comes on easily; and chest pain which is cardiac. All the signs and symptoms I never had before the Pfizer shot went in my right arm.  I am having an exercise stress test soon due to the objective physical signs and report of symptoms.