Age: 12.0
Sex: F
Vaccine: HPV4
Symptoms: Fatigue, Glossitis, Loss of personal independence in daily activities, Menstruation irregular, Mental impairment
Clinical narrative: inflammatory issues (cellulitis on finger, inflammation on lips and tongue); inflammatory issues (cellulitis on finger, inflammation on lips and tongue); heart palpitations; chronic migraines/neurological injuries; vision issues/neurological injuries; panic attacks; autonomic injury/autonomic dysfunctions; inflammatory issues (cellulitis on finger, inflammation on lips and tongue); autoimmune injury/autoimmune disorder; first GARDASIL dose on 07-MAR-2020, second dose on 13-MAR-2021; premature ovarian failure (skipping mentrual cycles every 3 months,stopped menstruating,chronic fatigue,brain fog,lack of mental clarity,other emotional harm); Information has been received from a lawyer regarding a case in litigation and refers to an adolescent female patient (pt) (exact age was not provided; also reported as "minor child"). The pt's medical history included childhood illness: roseola at three years old. The pt's concurrent conditions and concomitant therapies were not provided. On 07-MAR-2020, at the age of 12 years, the pt was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection, administered for prophylaxis (exact dose, strength, lot #, expiry date, and route of administration were not provided), as recommended by her physician. On an unknown date, the pt experienced serious and debilitating injuries, including but not limited to autonomic, autoimmune, and neurological injuries and resulting sequelae. In January 2021, she started skipping menstrual cycles every 3 months (it was reported that until that, pt had regular menstrual cycles). On an unknown date, following the first quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, the pt also started developing inflammatory issues: cellulitis on her finger and inflammation on her lips and tongue. On 13-MAR-2021, at the age of 13 years, the pt received second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), as recommended by her physician. Following the second quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, the pt continued to experience missed menstrual cycles. She had her menstrual cycles every three months until January 2022, when she stopped menstruating. She missed her menstrual cycles from January until October 2022, when it was induced by her medical doctors. Following the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccinations, in addition to issues involving her reproductive system, the pt also developed heart palpitations, chronic migraines, vision issues, chronic fatigue, brain fog, lack of mental clarity, panic attacks, and other emotional harm. The pt has seen multiple physicians of different specialties to address her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries and was no longer able to engage in activities that a normal young person would enjoy. Prior to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccinations, the pt had always been in the gifted programs at all her schools and maintained a high grade point average (GPA). She enjoyed horseback riding, animals, and art. Based upon her chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, she has been diagnosed with various medical conditions, including but not limited to, premature ovarian failure (POF). The pt contended that her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological, injuries, including but not limited to, POF as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which are alleged herein and all of which were caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. As a proximate result of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), the pt suffered and continued to suffer severe and permanent physical injuries, and associated symptomatology and has suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the pt had suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of the events was considered not recovered.   The reporter considered all the events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). The reporter considered all events to be disabling.