Sex: F
Vaccine: VARZOS
Symptoms: Condition aggravated, Hypoaesthesia, Impaired work ability, Injected limb mobility decreased, Loss of personal independence in daily activities
Clinical narrative: retriggered pinched nerve on left side of my neck; great pain in left arm; inability to use my left arm much due to pain and numbness; Inability use arm; Fever; Total body aches; impacted my ability to work, perform basic daily tasks; impacted my ability to work, perform basic daily tasks; This serious case was reported by a consumer via sales rep and described the occurrence of pinched nerve in a 63-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included losartan for product used for unknown indication, clonidine for product used for unknown indication, chlorthalidone for product used for unknown indication and empagliflozin (Jardiance) for product used for unknown indication.   On 25-JAN-2024, the patient received Shingrix (left arm), losartan, clonidine, chlorthalidone and Jardiance. In JAN-2024, 48 hrs after receiving Shingrix, the patient experienced fever (Verbatim: Fever), general body pain (Verbatim: Total body aches), impaired work ability (Verbatim: impacted my ability to work, perform basic daily tasks) and activities of daily living impaired (Verbatim: impacted my ability to work, perform basic daily tasks). On 27-JAN-2024, the patient experienced pinched nerve (Verbatim: retriggered pinched nerve on left side of my neck) (serious criteria other: Serious per reporter), pain in arm (Verbatim: great pain in left arm) (serious criteria other: Other medically imp. condition), numbness of upper extremities (Verbatim: inability to use my left arm much due to pain and numbness) (serious criteria other: Serious per reporter) and arm discomfort (Verbatim: Inability use arm) (serious criteria other: Serious as reporter). The patient was treated with paracetamol (Tylenol). The action taken with losartan was unknown. The action taken with clonidine was unknown. The action taken with chlorthalidone was unknown. The action taken with Jardiance was unknown. The outcome of the pinched nerve, pain in arm, numbness of upper extremities and arm discomfort were not resolved and the outcome of the fever, impaired work ability and activities of daily living impaired were not reported and the outcome of the general body pain was resolved.   The reporter considered the pinched nerve, pain in arm, numbness of upper extremities and arm discomfort to be related to Shingrix. It was unknown if the reporter considered the fever, general body pain, impaired work ability and activities of daily living impaired to be related to Shingrix.     The company considered the pinched nerve, pain in arm, numbness of upper extremities and arm discomfort to be related to Shingrix. It was unknown if the company considered the fever, general body pain, impaired work ability and activities of daily living impaired to be related to Shingrix.   Additional Information: GSK Receipt Date: 27-Jan-2024 The reporter reported that the patient received Shingrix vaccine and experienced retriggered pinched nerve on left side of her neck which caused great pain and inability to use her left arm much due to pain and numbness. The reporter stated that after the vaccine patient had fever and total body aches within 48 hours.  The patient received Tylenol and total body ache stopped but the pain of the re-triggered pinched nerve remains to this day.   The reported stated that this had impacted on patients ability to work, perform basic daily tasks and had cost her a couple hundred dollars thus far in trying to resolve the problem. The patient received the Shingrix vaccine as suggested by her primary physician.   There was no primary disease. It was unknown if the reporter considered the pinched nerve, pain in arm, numbness of upper extremities, discomfort, fever, general body pain, impaired work ability and activities of daily living impaired to be related to losartan, clonidine, chlorthalidone and Jardiance. The reporter consented to follow up.