Sex: F
Vaccine: COVID19
Symptoms: COVID-19, Vitreous degeneration, Vitreous detachment
Clinical narrative: vitreous detachment in her eyes; gel like fluid at the back of the eye that becomes old and liquidly; Covid-19; This spontaneous case was reported by a patient and describes the occurrence of VITREOUS DETACHMENT (vitreous detachment in her eyes) and VITREOUS DEGENERATION (gel like fluid at the back of the eye that becomes old and liquidly) in a female patient of an unknown age who received SPIKEVAX NOS (SPIKEVAX NOS) (batch no. ASKU) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 (got COVID-19 at mid FEB2023.) in February 2023. Previously administered products included for COVID-19 prophylaxis: MODERNA (Dose 1) on 11-Mar-2021, MODERNA (Dose 2) on 08-Apr-2021, MODERNA (Dose 3) on 08-Dec-2021 and MODERNA (Dose 4) on 20-Jul-2022. Past adverse reactions to the above products included No adverse event with MODERNA, MODERNA, MODERNA and MODERNA.    On 16-Dec-2022, the patient received fifth dose of SPIKEVAX NOS (SPIKEVAX NOS) (unknown route) 1 dosage form. In February 2023, the patient experienced COVID-19 (Covid-19). On 04-Nov-2023,  after starting SPIKEVAX NOS (SPIKEVAX NOS), the patient experienced VITREOUS DETACHMENT (vitreous detachment in her eyes) (seriousness criterion medically significant) and VITREOUS DEGENERATION (gel like fluid at the back of the eye that becomes old and liquidly) (seriousness criterion medically significant). At the time of the report, VITREOUS DETACHMENT (vitreous detachment in her eyes) and VITREOUS DEGENERATION (gel like fluid at the back of the eye that becomes old and liquidly) had not resolved and COVID-19 (Covid-19) outcome was unknown.            No concomitant medication was reported.  Three weeks ago, on 04NOV2023 patient experienced vitreous detachment in her eyes, she started to see flashing like crescent falling stars in the side of the left eye, she visited to an ophthalmologist and doctor mentioned this was a very very common issue, not everybody sees the flashes but it was a process of the gel like fluid at the back of the eye in between the eyeball and the retina that becomes old and liquidly, it's no longer a gel and as that happens, it pulls away from the retina, so there was a risk as this process happens of a Retinal-tear or a Retinal-detachment.   No treatment medication was reported.  Company comment:  This is a Spontaneous case concerning a female patient of unknown age, with no reported medical history, who experienced the unexpected serious (medically significant) events of vitreous detachment, vitreous degeneration and non-serious event of COVID-19. About 2 months after the administration of SPIKEVAX COVID-19 VACCINE NOS, used as a fifth dose, the patient had COVID-19. About 11 months after vaccination, she started to see flashing like crescent falling stars in the side of the left eye. She visited an ophthalmologist, and it is a process of the gel like fluid at the back of the eye in between the eyeball and the retina that becomes old and liquidly. She was also diagnosed with vitreous detachment. No further information on clinical course, investigations and treatment received was available in the report. COVID-19 could be a contributor risk factor to develop the events. The benefit-risk relationship of SPIKEVAX COVID-19 VACCINE NOS is not affected by this report.   Reporter did not allow further contact