Age: 48.0
Sex: M
Vaccine: COVID19, COVID19, COVID19
Symptoms: COVID-19, Vaccination failure
Clinical narrative: Random hematomas or blood clots in feet and hands; Peripheral neuropathy in his hands and feet/ had neuropathy; Random hematomas or blood clots in feet and hands; His skin gets really cold when it is freezing; When it is hot they are burning; Numbness/His arms are completely numb; His heart races; Blood pressure raised 20 points; Decreased blood flow to hands and feet/feels like his circulation is completely cut off; wakes up in the middle of the night; Couldn't sleep thru the night; He says his ANA shot up from 1:160 to 1:640/antibodies greater than 2500; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program (159558). The reporter is the patient.  A 48 year-old male patient received bnt162b2 (BNT162B2), administration date 11Jan2022 (Lot number: FL3197) at the age of 48 years as dose 3 (booster), single for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. Vaccination history included: Bnt162b2 (DOSE 1:, LOT: EN6208, ), administration date: 14Mar2021, when the patient was 47 years old, for COVID-19 Immunization; Bnt162b2 (DOSE 2:, LOT: EW0151, ), administration date: 06Apr2021, when the patient was 47 years old, for COVID-19 Immunization. The following information was reported: NEUROPATHY PERIPHERAL (medically significant) with onset 11Jan2022, outcome "recovering", described as "Peripheral neuropathy in his hands and feet/ had neuropathy"; THROMBOSIS (medically significant) with onset 11Jan2022, outcome "not recovered "described as "Random hematomas or blood clots in feet and hands", PERIPHERAL COLDNESS (non-serious) with onset 11Jan2022, outcome "not recovered" and described as "His skin gets really cold when it is freezing"; BURNING SENSATION (non-serious) with onset 11Jan2022, outcome "not recovered", described as "When it is hot they are burning"; HYPOAESTHESIA (non-serious) with onset 11Jan2022, outcome "not recovered", described as "Numbness/His arms are completely numb"; HEART RATE INCREASED (non-serious) with onset 11Jan2022, outcome "not recovered", described as "His heart races"; BLOOD PRESSURE INCREASED (non-serious) with onset 11Jan2022, outcome "not recovered", described as "Blood pressure raised 20 points"; POOR PERIPHERAL CIRCULATION (non-serious) with onset Jan2022, outcome "not recovered", described as "Decreased blood flow to hands and feet/feels like his circulation is completely cut off"; MIDDLE INSOMNIA (non-serious) with onset Jan2022, outcome "not recovered", described as "wakes up in the middle of the night"; HAEMATOMA (non-serious) with onset 02Feb2022, outcome "not recovered", described as "Random hematomas or blood clots in feet and hands"; INSOMNIA (non-serious) with onset 2022, outcome "recovered", described as "Couldn't sleep thru the night"; ANTINUCLEAR ANTIBODY INCREASED (non-serious) with onset 2022, outcome "not recovered", described as "He says his ANA shot up from 1:160 to 1:640/antibodies greater than 2500". The patient underwent the following laboratory tests and procedures: antibody test: (unspecified date) 320, notes: first two Pfizer doses his antibodies didn't go above 320; (unspecified date) 2500, notes: After the third dose it went greater than 2500; antinuclear antibody: (unspecified date) 1:160, notes: ANA shot up from 1:160 to 1:640 ranges expressed as a ratio; (unspecified date) 1:640, notes: ANA shot up from 1:160 to 1:640 ranges expressed as a ratio as an autoimmune measurement; blood pressure measurement: (unspecified date) 107/65, notes: normal blood pressure; (11Jan2022) 140/85, notes: His peak high blood pressure; heart rate: (11Jan2022) races; laboratory test: (unspecified date) unknown results, notes: Taking lots of lab tests. Therapeutic measures were taken as a result of neuropathy peripheral, thrombosis, peripheral coldness, burning sensation, hypoaesthesia, heart rate increased, blood pressure increased, poor peripheral circulation, middle insomnia, haematoma, insomnia, antinuclear antibody increased. The patient reported he had peripheral neuropathy in his hands and feet that started the night of the third dose of the vaccine. His skin got really cold when it was freezing, and when it was hot they were burning, which was part of peripheral neuropathy. He had neuropathy and numbness on the first night of getting the booster dose. He says another thing was that when he climbed a set of stairs, his heart races in a way it didn't use to.  He reported his blood pressure raised 20 points; this started the night of the third dose of the vaccine. His normal blood pressure was 107/65, and his peak high blood pressure after booster dose of the vaccine was 140/85. He also experienced decreased blood flow to hands and feet that began shortly after 11Jan2022; he had decreased blood flow to his arms and legs, and he wakes up in the middle of the night and his arms were completely numb, and he felt like his circulation was completely cut off. When he was driving he had to untie his shoes, or he felt like he had no circulation to his feet.  He had a couple random hematomas or blood clots in feet and hands which began shortly after 11Jan2022. He had pictures of the hematomas as well. He said the first hematoma was on 02Feb2022 which was on his foot, and then on 12Feb2022 the second hematoma was on his hand.  The patient stated he was getting treated, but these things were not better, but his peripheral neuropathy had improved slightly with gabapentin. He started taking gabapentin four weeks ago, during Feb2022, and he takes 600mg a day by mouth; before taking gabapentin he couldn't sleep thru the night, and after taking it he can sleep. He had taken lots of lab tests, and he knows after the first two Pfizer doses his antibodies didn't go above 320, then after the third dose it went greater than 2500.