Sex: U
Vaccine: VARZOS, VARZOS
Symptoms: Vaccination failure
Clinical narrative: Suspected vaccination failure; got it in my right eye; had 3 out breaks; Covid-19; I believe Covid weakened my immune system; Eye pressure; nerve tingling every so often that side of my head.; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   On an unknown date, the patient received the 2nd dose of Shingrix and the 1st dose of Shingrix. On an unknown date, an unknown time after receiving Shingrix and Shingrix, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant), ophthalmic herpes zoster (Verbatim: got it in my right eye) (serious criteria GSK medically significant), shingles (Verbatim: had 3 out breaks), covid-19 (Verbatim: Covid-19), decreased immune responsiveness (Verbatim: I believe Covid weakened my immune system), sensation of pressure in eye (Verbatim: Eye pressure) and tingling (Verbatim: nerve tingling every so often that side of my head.). The patient was treated with valaciclovir (Valacyclovir), brimonidine and prednisone. The outcome of the vaccination failure, ophthalmic herpes zoster, shingles, covid-19, decreased immune responsiveness and tingling were not reported and the outcome of the sensation of pressure in eye was resolved.   It was unknown if the reporter considered the vaccination failure, ophthalmic herpes zoster, shingles, covid-19, decreased immune responsiveness, sensation of pressure in eye and tingling to be related to Shingrix and Shingrix.     The company considered the vaccination failure and ophthalmic herpes zoster to be unrelated to Shingrix and Shingrix. It was unknown if the company considered the shingles, covid-19, decreased immune responsiveness, sensation of pressure in eye and tingling to be related to Shingrix and Shingrix.   Additional Information: GSK Receipt Date: 18-SEP-2024 This case was reported by a patient via interactive digital media. The patient reported that received both Shingrix shots, since had three out breaks of shingles. It was got it in right eye earlier that year a few months after getting Covid for the first time. The patient believe covid weakened immune system. The shot did not stop from getting shingles, it just lessons of the effects. The patient given Valacyclovir tablets, Brimonidine drops for pressure in eye and Prednisone drops in eye.  Still on the Prednisone drops every other day.  Eye pressure was back to normal. However, the patient got nerve tingling every so often that side of the head. The reporter was told shingles had a sneaky way of coming back, so take the medicines. This case was considered as suspected vaccination failure since the details regarding time to onset and laboratory confirmation of shingles were unknown at the time of reporting.; Sender's Comments: Vaccination failure is a listed event which, due to the following criteria (insufficient information provided about details regarding time to onset and  and laboratory confirmation regarding disease) is considered unrelated to GSK vaccine Shingrix(dose 1 and 2).