Age: 40.0
Sex: F
Vaccine: COVID19
Symptoms: Investigation, Lung hyperinflation, Mood altered, Pain in extremity, Paraesthesia
Clinical narrative: multiple autoimmune diseases/autoimmune was flaring up; Graves' disease/diagnosed with graves and thyroid eye disease; Thyroid eye disease/diagnosed with graves and thyroid eye disease; vaccine has destroyed her life; Hashimoto's thyroiditis; lungs mild inflammatory with thickening again; pain in arms; right ear pain; allergic conjunctivitis; blood pressure; constipation; numbness and tingling and left ear completely numb; numbness and tingling and left ear completely numb; sinus one because she has sinus issues; changes in mood present; lack of concentration; brain fog; headache; thickening of the lungs/lungs were mildly hyperinflated; bleeding on the surface of her left eye; felt sick like had the flu; This is a spontaneous report received from a Consumer or other non HCP from medical information team and product quality group.  A 42-year-old female patient received BNT162b2 (BNT162B2), on 17Jul2022 as dose 3 (booster), single (Lot number: FN2908) at the age of 40 years for covid-19 immunisation. The patient's relevant medical history included: "asthma attacks", start date: 2019 (unspecified if ongoing), notes: prior to covid coming; "thinks it was early covid", start date: 2019 (unspecified if ongoing); "constipation" (unspecified if ongoing), notes: did have some of that before; "sick", start date: 2019 (unspecified if ongoing), notes: prior to covid coming. The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (dose 1, batch/lot number EW0158), administration date: 31Jul2021, when the patient was 39-year-old, for COVID-19 immunization, reaction(s): "had pain in her arms", "she also felt sick like had the flu for about 24 hours"; BNT162b2 (dose 2, batch/lot number EW0169), administration date: 13Aug2021, when the patient was 39-year-old, for COVID-19 immunization, reaction(s): "Graves", "thyroid eye disease", "had pain in her arms", "she also felt sick like had the flu for about 24 hours", "the first was done on 31Jul2021/the second dose was on 13Aug2021", "eye pain", "ear pain", "dry eye", "Hashimoto's". The following information was reported: EYE HAEMORRHAGE (medically significant) with onset 02Mar2023, outcome "unknown", described as "bleeding on the surface of her left eye"; LUNG HYPERINFLATION (non-serious) with onset 12Mar2024, outcome "unknown", described as "thickening of the lungs/lungs were mildly hyperinflated"; AUTOIMMUNE DISORDER (medically significant), outcome "not recovered", described as "multiple autoimmune diseases/autoimmune was flaring up"; GRAVES' DISEASE (medically significant), outcome "not recovered", described as "Graves' disease/diagnosed with graves and thyroid eye disease"; ENDOCRINE OPHTHALMOPATHY (medically significant), outcome "not recovered", described as "Thyroid eye disease/diagnosed with graves and thyroid eye disease"; IMPAIRED QUALITY OF LIFE (medically significant), outcome "not recovered", described as "vaccine has destroyed her life"; AUTOIMMUNE THYROIDITIS (medically significant), outcome "unknown", described as "Hashimoto's thyroiditis"; PNEUMONITIS (medically significant), outcome "unknown", described as "lungs mild inflammatory with thickening again"; PAIN IN EXTREMITY (non-serious), outcome "unknown", described as "pain in arms"; INFLUENZA LIKE ILLNESS (non-serious), outcome "recovered", described as "felt sick like had the flu"; EAR PAIN (non-serious), outcome "unknown", described as "right ear pain"; CONJUNCTIVITIS ALLERGIC (non-serious), outcome "unknown", described as "allergic conjunctivitis"; BLOOD PRESSURE ABNORMAL (non-serious), outcome "unknown", described as "blood pressure"; CONSTIPATION (non-serious), outcome "unknown"; HYPOAESTHESIA (non-serious), PARAESTHESIA (non-serious), outcome "unknown" and all described as "numbness and tingling and left ear completely numb"; SINUS DISORDER (non-serious), outcome "unknown", described as "sinus one because she has sinus issues"; MOOD ALTERED (non-serious), outcome "unknown", described as "changes in mood present"; DISTURBANCE IN ATTENTION (non-serious), outcome "unknown", described as "lack of concentration"; BRAIN FOG (non-serious), outcome "unknown"; HEADACHE (non-serious), outcome "unknown". The events "multiple autoimmune diseases/autoimmune was flaring up", "thyroid eye disease/diagnosed with graves and thyroid eye disease", "vaccine has destroyed her life", "bleeding on the surface of her left eye", "hashimoto's thyroiditis" and "allergic conjunctivitis" required physician office visit. The events "graves' disease/diagnosed with graves and thyroid eye disease" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Anti-thyroid antibody: (02Nov2021) 98.8, notes: high - for Hashimoto's and not for the graves diagnosis; (02Nov2021) 98.9; (17Jul2023) 306; (25Aug2023) it was way high; Anti-thyroid antibody positive: (28Aug2023) 8.30, notes: high; Blood test: (unspecified date) thyroid positive; (25Aug2023) Unknown results; Blood thyroid stimulating hormone: (02Nov2021) 1.72, notes: normal; (25Aug2023) 0.01, notes: low; Computerised tomogram: (unspecified date) diagnosed thyroid eye disease, notes: mild symmetric prominence and the outside eye was looking prominent; (unspecified date) shows the eye problems, notes: had to do it to diagnose her eyes; exam: (unspecified date) lungs with mild inflammatory with thickening again, notes: suspected in perihilar and basilar regions and has no pleural effusion or pneumothorax; Scan: (unspecified date) indicated thyroid eye disease; Scan brain: (unspecified date) negative; Thyroid function test: (unspecified date) diagnosed graves disease and thyroid eye disease, notes: thyroid levels; (unspecified date) Unknown results, notes: before she was vaccinated; Thyroid stimulating immunoglobulin: (25Aug2023) 5, notes: high - to diagnose her with graves; (28Aug2023) 5.42, notes: high; Thyroxine: (02Nov2021) 1.0, notes: normal; (25Aug2023) 1.61, notes: high; Tri-iodothyronine: (25Aug2023) 6.29, notes: high; X-ray: (unspecified date) lungs were mildly hyperinflated. Clinical course: The patient was calling about Pfizer COVID vaccine which destroyed caller's life, didn't want to take, got sick, has multiple autoimmune diseases now, Graves' disease, thyroid eye disease (TED). She wanted to report the timeline of that and wanted to know if there was a class action lawsuit going on. She wanted to report this as proof. The patient would love to have open dialogue, vaccine has destroyed her life, was living in (withheld), now living with parents in (withheld). The patient stated has destroyed life, now was having this clown operation, this was dealing with caller's life. The vaccine made patient sick and had to go to (withheld), took caller's life away, now sick. The patient had such a bad reaction and was still sick and has been sick many years now because of this and prefers to be contacted by phone. There was more a long term reaction and short term reaction and had pain in arms that lasted a little while and arm pain after being vaccinated and boosted that occurred after all three doses and she also felt sick like had the flu for about 24 hours; then long term was that she was diagnosed with graves and thyroid eye disease. She had eye pain after being vaccinated and later on was diagnosed because she did not have access to getting blood work because of the pandemic and did not get diagnosed until later. This was so bad it gives her anxiety. About 4 months later, she started having eye pain and that happened with symptoms right around there the week of covid and mostly her right eye and right ear pain and then she started to have dry eye up until then and after that it was like dry eye all the time and eye pain a lot. Then she did not do blood work testing and they gave us the vaccine free and did not pay for any follow up to see if they in fact did damage to bodies so she was in (redacted) but living in (redacted) at her parents when she got the vaccines and did not have access to a doctor while this autoimmune was flaring up. She then had a blood shot left eye and later on that started to build up and that was she thinks 30Jan2023 and had eye pain in the right eye that was sharp eye pain and this was not the blood shot time but was just a sharp eye pain again and had that in the right eye and then it came again for another incident on the bloodshot right eye on 02Mar2023 and there was bleeding on the surface of her left eye. The doctors were incompetent and thought this was from swimming but she swam her entire life and never had that knew something was wrong and they dismissed it and said it was from swimming. Then she saw another eye doctor on general ophthalmology and went on 20Feb2023 to another eye doctor and the other was a retinal eye doctor but this was the regular ophthalmologist Dr. (Name) and he misdiagnosed her and said she had dry eye so she got three misdiagnoses and knew it was something more serious happening so did speak to a doctor in 2022 for a virtual visit and she has all the doctor notes and did see someone on 11Jan2022 named Dr. (Name) to tell her that she had right side eye pain and pressure and deep eye pain and pressure that they thought likely from covid but the caller was vaccinated and did not think it was covid and thinks she had covid prior to this as she was throwing up all year and in 2019 prior to covid coming she was sick with asthma attacks and sick and gave it to her parents when she came back and thinks it was early covid then and all these symptoms happened after the vaccine. She saw another eye doctor on 25Feb2022 and saw Dr. (Name) who said she had eye pain and it was her right eye again and was always the right eye at first. She was looking at her medical chart on the website pulled from all hospitals she went to and was going to give the first time blood work tested and the unfortunate conundrum was that she only did thyroid bloodwork before she was vaccinated. Her thyroid levels was what diagnosed her with graves disease and thyroid eye disease was a component of that and comes from testing and looking at the eyes to be diagnosed by the eye doctor. On 02Nov2021, they tested her TSH, T4 and TPO levels and did not do a T3 and that may would have showed it; the thyroid antibodies of Hashimoto's were high and she already had that, and her thyroid antibodies were high so those were 98.8 for Hashimoto's and not for the graves diagnosis. The TPO bloodwork on 02Nov2021 was 98.9 and she thought since she was genetically predisposed she would not get vaccinated but all the doctors were forcing her to and Pfizer and all other companies said it was totally safe if you have autoimmune conditions. The antibodies mean she did not have it but the disease did not happen until after her vaccination; T4 was normal and was 1.0 and then TSH was 1.72 which was normal and the only one high was the antibodies which she already had. She went to the ER and the next time was then with heart palpitations on 25Aug2023 they did better testing there tested TSH 0.01 low, T4 was 1.61 high, T3 was 6.29 high so all abnormal and out of range; did the thyroglobulin antibody to diagnose her with graves and it was 5 which was high. Then there was also the few other bloodwork and the TPO again and it was way high after that was 306 and that was on 17Jul2023; did a thyroid stimulating immunoglobulin test and did it the same day at the hospital on 28Aug2023 and it was 5.42 high. On 28Aug2023 did a thyrotropin receptor antibody and was also high and was 8.30 and she never had those before never had thyroid positive blood work and once she had that, they tested all these extra things. Saw a doctor few days later and tested for more and prior to this diagnosis for graves disease she also saw an eye doctor that spring and saw Dr. (Name) on 14Jul2023 and she had dry eye in both eyes, allergic conjunctivitis and he put Hashimoto's thyroiditis but he said her eyes have mild swelling and noticed proptosis of the left eye and she has both Hashimoto's and graves antibodies at the same time; she believed it had to be vaccine and it was not a normal thing to have both high and low of thyroid disorders. Her left eye and right both had pain and the right had more pain and the left eye looks like it was bulging. Then she saw another doctor on 18Jul2023 and he said they needed to draw more studies about Graves disease since her eye was swollen and she saw Dr. (Name) and Dr (Name) and she was diagnosed with graves and in Jul prior to that her eye looked a little funky and it was a nightmare. She took Metoprolol for blood pressure and along with that methimazole on 26Aug. She has not worked and has been out of work and lost tons of money and it ruined her life. When she was in Greece, started those medications to counteract and believed it was pharmaceutical poisoning. The Metoprolol is ER succinate and was 25mg tablets and thinks she took one tablet once per day and the NDC 45963-0709-11 and on the tablets says A9. For the Methimazole one, it was by Strides and was 10mg and she was doing a half tablet three times a day at that point so really 5mg every time she would take it and it has NDC 64380-0213-01 and on the tablet was written EM10. She never took flu shots and never did these types of things and was not a medicine person and barely takes medicine because she always has reactions and the vaccine permanently altered her life. She got back to (redacted) at the end of Nov2023 to the (redacted) and went to the clinic 04Dec2023 and saw an ocular plastic surgeon and saw Dr. # and that doctor diagnosed her with graves and thyroid eye disease. From there she has spent over a year now from 2023 to now dealing with the clinic mostly and she has eye appointments and virtual visits and had to be on (redacted) because she was not working and this uprooted her entire life and was insane and she tried functional medicine to help her holistically with a AIP diet and GI health trying to clear up her constipation and she did have some of that before. Her thyroid has been vacillating between abnormal and normal based on diet and she was trying to fight this, and it has been abnormal and still abnormal now and probably was abnormal much longer. Doctors think she has had graves for 2 years and it was possible it was the vaccine and possibly then covid made it worse and the vaccine was supposed to stop it or make it less worse; she saw the post covid clinic and the nurse triaged her with pulmonology and cardiology and she was seeing endocrinology already and they did not see any heart damage as the vaccine picks and chooses where it affects and it can be sometimes in the brain, heart, lungs or thyroid or whatever. Pulmonology said she had some thickening of the lungs on 12Mar2024 and had an Xray done and could this be from Metoprolol reaction or from the vaccine; the Xray says her lungs were mildly hyperinflated on the current exam with mild inflammatory with thickening again suspected in perihilar and basilar regions and has no pleural effusion or pneumothorax. The caller did not want a CT scan due to not wanting more radiation and had a CT scan of her face and had to do it to diagnose her eyes. Dr. (Name) said it was possible it was the vaccine and they said everyone reacts differently. The scan shows the eye problems and she had thousands of tests because of this and blood work and she was never sick before. Asked will she get a copy of this report. She got back on Methimazole on 04Dec2023 because her eye doctor said she had graves disease and started it and had not had asthma like before and had numbness and tingling and left ear completely numb on Christmas morning; the doctor was in a panic and the patient's brain scan was negative and she had a sinus one because she has sinus issues and the eye scan they gave her indicated thyroid eye disease so the CT diagnosed thyroid eye disease and said mild symmetric prominence and the outside eye was looking prominent and she finally got off the Methimazole and was trying to treat this on 09Feb2024 and has been off since with functional medicine and she may need a thyroidectomy neck surgery and she should not get radioactive iodine so the choice was to get back on Methimazole or surgery on the thyroid. Post covid clinic said they discussed lung covid symptoms and triaged her and she did have changes in mood present and lack of concentration, brain fog, headache and eye pain. She would like to know if other patients have this horrible health crisis or anything she can use to help combat or reverse it. Therapeutic measures were taken as a result of graves' disease, endocrine ophthalmopathy, blood pressure abnormal.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202500020994 same patient, different event/dose;US-PFIZER INC-202500020996 same patient, different event/dose;US-PFIZER INC-202500020995 same patient, different event/dose;