Age: 31.0
Sex: F
Vaccine: COVID19
Symptoms: Blood pressure measurement, Computerised tomogram head, Dysarthria, Dysphemia, Feeling abnormal
Clinical narrative: Felt bad; Arm pain; Sweating; Cold feet; Slurred speech; Elevated blood pressure; Stuttering; Body ache; Headache; tremors; This spontaneous case was reported by a health care professional (subsequently medically confirmed) and describes the occurrence of FEELING ABNORMAL (Felt bad), PAIN IN EXTREMITY (Arm pain), HYPERHIDROSIS (Sweating), PERIPHERAL COLDNESS (Cold feet) and DYSARTHRIA (Slurred speech) in a 31-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 028L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 21-Jan-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 21-Jan-2001, the patient experienced TREMOR (tremors). On 21-Jan-2021, the patient experienced FEELING ABNORMAL (Felt bad), PAIN IN EXTREMITY (Arm pain), HYPERHIDROSIS (Sweating), PERIPHERAL COLDNESS (Cold feet), DYSARTHRIA (Slurred speech), HYPERTENSION (Elevated blood pressure), DYSPHEMIA (Stuttering), MYALGIA (Body ache) and HEADACHE (Headache). The patient was treated with LORAZEPAM (intravenous) 21-Jan-2021 for Adverse event following immunisation, at a dose of 2 milligram; DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) (intravenous) 21-Jan-2021 for Adverse event following immunisation, at an unspecified dose and frequency and STEROIDS on 21-Jan-2021 for Adverse event following immunisation, at an unspecified dose and frequency. In February 2021, FEELING ABNORMAL (Felt bad), PAIN IN EXTREMITY (Arm pain), HYPERHIDROSIS (Sweating), PERIPHERAL COLDNESS (Cold feet), DYSARTHRIA (Slurred speech), HYPERTENSION (Elevated blood pressure), DYSPHEMIA (Stuttering), TREMOR (tremors), MYALGIA (Body ache) and HEADACHE (Headache) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 21-Jan-2021, Blood pressure measurement: 183/90 (Inconclusive) Inconclusive. On 21-Jan-2021, Computerised tomogram head: normal (normal) CT of brain was normal. On 27-Jan-2021, Magnetic resonance imaging: abnormal (abnormal) abnormal  flare signal regions in the brain which may signify early microvascular ischemic changes, a demyelinating process, vasculitis, or sequelae for migraines. On 05-Feb-2021, Magnetic resonance imaging: normal (normal) indicated no acute intracranial abnormalities, no diffusion evidence of acute ischemia, no brain parenchymal edema, hemorrhage or mass effect, no enhancing intracranial mass or suspicious intracranial enhancement, multiple scattered punctate foci of unenhancing white matter, signal alteration which are nonspecific but unchanged in comparison to 27 Jan 2021..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No concomitant medications were reported. In addition to the ones reported above , stroke alert was also performed in Emergency room.