Sex: F
Vaccine: COVID19
Symptoms: Hypersensitivity, Immune system disorder, Pruritus, Skin burning sensation, Skin depigmentation
Clinical narrative: covid shot affected her immune system; allergies every morning; skin went from itching to burning resulting in marks all over her body; skin went from itching to burning resulting in marks all over her body; skin went from itching to burning resulting in marks all over her body; This is a spontaneous report received from a Consumer or other non HCP from License Party.  A 65-year-old female patient received BNT162b2 (BNT162B2), in 2022 as dose 1, single (Batch/Lot number: unknown) for covid-19 immunisation; dupilumab (DUPILUMAB), in Jan2022 (ongoing) as 300 mg) subcutaneous for dermatitis atopic. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: IMMUNE SYSTEM DISORDER (non-serious), outcome "recovering", described as "covid shot affected her immune system"; HYPERSENSITIVITY (non-serious), outcome "unknown", described as "allergies every morning"; PRURITUS (non-serious), SKIN BURNING SENSATION (non-serious), SKIN DEPIGMENTATION (non-serious), outcome "unknown" and all described as "skin went from itching to burning resulting in marks all over her body". The action taken for dupilumab was dosage not changed.  Additional information: This case involves a 65 years old female patient who reported COVID-19 vaccine shot affected her immune system while being treated with DUPILUMAB [DUPIXENT] delivered via single dose prefilled syringe. The patient's past medical history, medical treatment(s), vaccination(s) and family history were not provided.  In January 2022, the patient started taking DUPIXENT (DUPILUMAB) Solution for injection in prefilled syringe at dose 300 mg (unknown: strength, frequency) subcutaneously for Dermatitis atopic.  In 2022, the patient started taking COVID-19 vaccine (at unknown dose, frequency, route, strength, device) for immunisation.  On an unknown date the patient developed a non-serious event "covid shot affected her immune system "(immune system disorder) (unknown latency) following the first dose intake (unknown expiry date, batch number) of DUPILUMAB and COVID-19 vaccine. On an unknown date the patient developed a non-serious event "allergies every morning" (hypersensitivity) (unknown latency) following the first dose intake (unknown expiry date, batch number) of DUPILUMAB and COVID-19 vaccine. On an unknown date the patient developed a non-serious event "skin went from itching to burning resulting in marks all over her body" (pruritus), (skin burning sensation) and (skin discolouration) (unknown latency) following the first dose intake (unknown expiry date, batch num ber) of DUPILUMAB and COVID-19 vaccine.  Information regarding batch number and expiration date corresponding to the one at time of event occurrence was requested.  It was reported "having allergies every morning; Also, she received the Covid Shot in 2022; That affected her immune system and caused her skin to go from itching to burning resulting in marks all over her body. Missed Dose NOT reported.'  Action taken with DUPILUMAB: no action taken for immune system disorder  Action taken with COVID-19 vaccine: unknown for immune system disorder  It was not reported if the patient received a corrective treatment for immune system disorder  At time of reporting, the outcome was Recovering / Resolving for immune system disorder   No follow-up attempts are possible. Batch/lot number is not provided, and it cannot be obtained.