Age: 102.0
Sex: F
Vaccine: COVID19-2
Symptoms: Anticoagulant therapy, Asthenia, Blood pressure decreased, Blood pressure fluctuation, Blood pressure increased
Clinical narrative: BEFORE 09/15/2022 - VACCINATION DATE * Since 2019, noticed influenza and covid-19 vaccinations resulted in weakness and lethargy for about 2 weeks following. * Had one episode of severe respiratory distress after signification exertion in December 2019. * Occasional occasions of low blood pressure (BP) had been an issue for at least a decade prior.  Occasions of very high BP were beginning to be noticed in early 2022.  Systolic of up to 170 and diastolic of up to 100. But these were rare. * 07/23/2022 tested positive for Sars-COV2 and experienced a very mild illness over 3 weeks.  Was teated with Paxlovid. * 09/15/2022.  Bivalent vaccine administered.  We opted for just the covid-19 vaccination rather than the combined flu and covid-19 vaccination because I was concerned about the combined weakness and lethargy they would induce given her already diminished strength seemingly resulting from her covid-19 illness 2 months before.  POST VACCINATION * 09/15/2022 - 10/24/2022.      > Weakness and lethargy from this vaccination seemed to be somewhat more intense and certainly lasted longer, 4 weeks at least.  She was tiring just rolling over in bed.    > Breathing was sometimes elevated, and was distressed even with mild exertion such as rolling over in bed a few times.     > Wheezing accompanied respiratory distress at times.   > BP was oscillating, sometimes low enough to lose consciousness briefly and other times close to 180/95 * 10/24/2022 - 10/28/2022.  Visited the emergency room (ER) and was hospitalized for BP of 200/100 for at least 2 hours along with respiratory distress and wheezing.  Treatment was a change of her BP medication from Atenolol and Hydrochlorothiazide to corvedilol.  I was assured her BP was now steady. * 10/29/2022.  The day after discharge from the hospital, she briefly lost consciousness from low BP. * 11/02/2022.  Received flu shot so as to safely go to infusion center for Prolia injection. * 10/29/2023 - 11/18/2022.  Wildly oscillating BP, elevated breathing and wheezing even when completely at rest, recurring respiratory distress, and weekness continued. * 11/18/2022 - 11/20/2022.  On 11/18/2022 infusion center refused administering Prolia and advised she go to ER immediately.  She was hospitalized as a result.  Hospitalization was for the same reason as previous hospitalization, BP 200/100, respiratory distress, and wheezing.  Hospitalization found a blood clot and she is now being treated with eliquis. * 11/20/2022 - mid January 2023.  The same symptoms persisted, wildly oscillating BP, sometimes 200/100, sometimes as low as 63/40, unexplained rises and drops in BP, persistent elevated breathing and wheezing, and recurring respiratory distress. * Mid January to this date.  A slow and gradual stabilization of BP and a regain of strength has occurred.  Elevated breathing is still occurring but no occurrences of respiratory distress or systolic BP over 170.  Systolic is mostly in the 140s.  She can again walk 40 feet from her bedroom to the living room. * Her current physical condition is nearly what it was prior to covid-19 illness (on 07/23/2022) and the covid-19 booster (on 09/15/2022)  There is no date or time the adverse event started.  There is no adverse event in fact.  There was a progressive increase in intensity of adverse symptoms which probably started before the vaccination but dramatically intensified after.