Age: 18.0
Sex: F
Vaccine: HPV4
Symptoms: Disturbance in attention, Dizziness postural, Fatigue, Headache, Heart rate increased
Clinical narrative: POTS/ debilitating symptoms, including nausea, dizziness upon standing, chronic body pain, chronic headaches, syncope, rapid heart rate, difficulty concentrating, memory problems, insomnia, and chronic fatigue.; This spontaneous report was received from a lawyer, regarding a case in litigation and refers to 18 years-old female adult patient (pt). The patient's concurrent conditions, medical history and concomitant medications were not provided.   On 19-JUL-2021 and 20-JAN-2022, the patient was vaccinated with the first and second doses of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine(GARDASIL), respectively (doses, routes of administrations, anatomical locations, lot # and expiry dates were not provided) for preventing cervical cancer, as recommended by physician and consented by the patient; after being convinced by marketing that the vaccine was very safe.   It was reported that prior to receiving the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine(GARDASIL) vaccinations, she was able to work a rigorous schedule consisting of more than 40 hours per week assisting campers and teaching an active curriculum at the Science Museum as an intern. Thereafter, she was promoted to a paid position and was able to function and perform daily tasks efficiently. However, after the vaccination, on an unknown date,  she experienced life altering and debilitating symptoms, including nausea, dizziness upon standing, chronic body pain, chronic headaches, syncope, rapid heart rate, difficulty concentrating, memory problems, insomnia, and chronic fatigue. As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine(GARDASIL) symptoms, she has been unable to work fulltime because an eight-hour workday causes extreme fatigue, which impacts her ability to work consecutive days in a row. Her symptoms have negatively impacted her professional life.  As the months progressed, so did the pt's symptoms. She was seen by multiple physicians and specialists, including a neurologist for her complaints and based upon her chronic and severe post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine(GARDASIL) symptoms, the pt has been diagnosed with postural orthostatic tachycardia syndrome (POTS).  As a proximate result of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), the pt suffered and continued to suffer severe and permanent physical injuries, and associated symptomatology and suffered severe and permanent emotional injuries, including pain and suffering. The pt also had a substantial fear of suffering additional and ongoing harms, including but not limited to being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). The outcome of the events was considered to be not recovered.   The events were considered to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). The event of POTS was considered to be disabling.