Sex: F
Vaccine: PPV
Symptoms: Cough, Dizziness, Dysphonia, Dyspnoea, Fatigue
Clinical narrative: She reported that her sister had the same "severe respiratory reaction" to the vaccine that she experienced; Dry heaves; hair chills; vomiting; Fevers; Feels exhausted; weakness; hives; Difficulty Hearing; Quit breathing from her diaphragm; severe coughing episodes; Excessive mucus production; Blurred vision; Wheezing; Feels like her immune system has gone crazy; Difficulty speaking; Has not slept in weeks; shortness of breath; hoarseness; rapid heartbeat; sweats especially head; productive cough; Feels drugged up; Dizziness; This spontaneous report as received from a consumer refers to a 66 year old female patient with tobacco allergy. Prior, patient's sister experienced illness with respiratory distress on 16-JAN-2013, one day after vaccination with pneumococcal vaccine, polyvalent (23-valent)(PNEUMOVAX23) (MARRS case 1308USA014836). On 15-AUG-2013, the patient was vaccinated with pneumococcal vaccine, polyvalent (23-valent)(PNEUMOVAX23) lot # H013039 batch# J002646 for prevention of pneumonia. Dosing information and route of administration were not provided.   On 16-AUG-2013 (reported as the following day) the patient experienced severe coughing episodes, dry heaves, vomiting, wheezing and excessive mucus production. Additional symptoms included difficulty in breathing, blurred vision and dizziness. Treatment was sought through patient's physician in the form of "Pregnazone". at an unspecified dosage and frequency and an unspecified "Z-pack" antibiotic course. The adverse symptoms had not improved and patient had been forced to cancel her vacation and seek additional help of a Pulmonologist. It was reported that an X-ray and computed tomography (CT) scan were performed on 26-AUG-2013. Causality assessment was not provided.      The health care professional contacted during telephone follow up reported that the physician would be sending the information regarding the patient.  Follow up information has been received from the patient and a pulmonary nurse (patient's daughter) indicating that the patient herself was desperately worried because she was following the same course as her sister. The patient reported that she herself felt like her immune system had gone crazy, felt exhausted and had not slept in weeks. The patient still had blurred vision and dizziness as well as difficulty hearing and speaking. The patient had computed axial tomography (CAT) scans on 26-AUG-2013 that "showed nothing" and x-ray (results not provided).  Pulmonary nurse stated that hoped her mother would get better and though the problem might be a binder in the vaccine. The nurse suggested the chemist who makes the vaccineshould look into it and see what could be harming people.   At the time of the report, the patient's outcome for felt like her immune system had gone crazy, felt exhausted and had not slept in weeks was unknown.  Upon internal review, difficulty hearing was considered to be medically significant.  Additional information was received from the patient which reported that she "was stick after receiving the pneumonia vaccine and was experiencing dizziness, fevers and has quit breathing from (her) diaphragm. The patient stated she "did pulmonary exercises, and was still using prednisone (unspecified dosage/frequency and manufacturer) and hydrocodone (unspecified dosage/frequency and manufacturer) and felt drugged up.  Follow up information received from the physician who reported regarding patient and physician details. Patient's height and weight were reported as 5'3" (units unknown) and 130# (units unknown). The patient experienced allergic rhinitis and asthma. Patient's 61 year old sister also had adverse events following pneumococcal vaccine, polyvalent (23-valent)(PNEUMOVAX23) vaccination. On 15-AUG-2013 at 4:30pm, the patient was vaccinated with pneumococcal vaccine, polyvalent (23-valent)(PNEUMOVAX23). On 16-AUG-2013, the patient had shortness of breath, hoarseness, weakness, hives, heart rate increased, sweats especially head/hair chills. The symptoms started on the night of vaccination. Chest x-ray was normal, chest computed tomography was normal. The patient was treated with antibiotics, nebulizers and prednisone and specialists or MD visits to assess the patient condition.   This is one of the two cases from the same source.  Additional information is not expected.  Follow-up information was received from the patient on 12-MAR-2021.  On an unspecified date post vaccination, the patient experienced a severe respiratory reaction to the vaccine (hypersensitivity). Furthermore, it was reported that her sister had the same hypersensitivity to pneumococcal vaccine, polyvalent (23-valent)(PNEUMOVAX23) that she experienced (MARRS case 2103USA003881).  At the time of the report, the outcome of hypersensitivity was unknown. The causal relationship between the aforementioned event and the suspect vaccine was related.