Sex: U
Vaccine: FLUX
Symptoms: Respiratory disorder
Clinical narrative: This case was reported in a literature article and described the occurrence of respiratory disorder in a adult subject who received unspecified seasonal 2015-2016 influenza vaccine for prophylaxis. On an unknown date, less than a year after receiving unspecified seasonal 2015-2016 influenza vaccine, the subject developed respiratory disorder. Serious criteria included hospitalization. The outcome of respiratory disorder was unknown. The investigator considered that there was a reasonable possibility that the respiratory disorder may have been caused by unspecified seasonal 2015-2016 influenza vaccine. Relevant Tests: Laboratory tests were performed  between 1 December 2015 and 30 April 2016. The patient's nasopharyngeal specimen was collected before or equal to 10 days from the illness onset. [In this study, respiratory viral panels (RVP) tests (reverse transcription polymerase chain reaction tests) were not performed to detect the presence of multiple respiratory viruses including influenza, from a single nasopharyngeal specimen. Additional information was provided. This case was reported in a literature article and described the occurrence of acute respiratory illness in an adult patient of unspecified gender who was vaccinated with unspecified seasonal 2015-2016 influenza vaccine (manufacturer unknown) for prophylaxis. This case corresponds to figure 2 reported in this literature article. The patient was part of the report that aimed to explore potential bias among hospitalized adults for acute respiratory illness (ARI) in a community hospital during the 2015-2016 influenza season. Total 1200 adults were enrolled in the study. No information on patient's medical or family history or concurrent condition or concomitant condition was provided. On an unspecified date during 2015-2016 influenza season, the patient had received unspecified seasonal influenza vaccine (administration route and site unspecified, dosage unknown; batch number not provided). The age of vaccination was not provided. On an unspecified date between 1 December 2015 and 30 April 2016 an unknown period after vaccination, the patient's electronic medical record was extracted. The patient was admitted to community hospital with the symptoms of new or worsening acute respiratory illness for equal to or less than 72 hours. The patient's nasopharyngeal specimen was collected before or equal to 10 days from the illness onset. [In this study, respiratory viral panels (RVP) tests (reverse transcription polymerase chain reaction tests) were not performed to detect the presence of multiple respiratory viruses including influenza, from a single nasopharyngeal specimen. In this study, the influenza season was defined as the time during which influenza was circulating, as indicated by the first enrolled participant with a positive influenza test result until the end of April 2016]. The case has been considered as serious due to hospitalisation. Treatment was unknown. The outcome of the event was not provided. The author did not comment on relationship between the event of acute respiratory illness and unspecified seasonal 2015-2016 influenza vaccine. The author concluded "Clinical respiratory viral panels (RVPs) are useful for identifying the causative agent for patients hospitalized with an acute respiratory illness. We found no evidence that influenza vaccination status was related to clinical RVP testing. Because of the potentially serious consequences of influenza in hospitalized patients, rapid turnaround testing should be initiated irrespective of the vaccination status of the patient, to enable the clinician to continue antiviral treatment if influenza has been confirmed. Clinical RVP testing may be useful in vaccine effectiveness studies; additional studies in other influenza seasons and settings are warranted." Lab Comments: Laboratory tests were performed  between 1 December 2015 and 30 April 2016. The patient's nasopharyngeal specimen was collected before or equal to 10 days from the illness onset. [In this study, respiratory viral panels (RVP) tests (reverse transcription polymerase chain reaction tests) were not performed to detect the presence of multiple respiratory viruses including influenza, from a single nasopharyngeal specimen.