Sex: M
Vaccine: COVID19
Symptoms: Ejection fraction, Electrocardiogram, Magnetic resonance imaging heart, Myocarditis, SARS-CoV-2 test
Clinical narrative: Cardiac magnetic resonance (CMR)-proven myocarditis shortly after vaccination; This literature-non-study case was reported in a literature article and describes the occurrence of MYOCARDITIS (Cardiac magnetic resonance (CMR)-proven myocarditis shortly after vaccination) in an adult male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.    No Medical History information was reported.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced MYOCARDITIS (Cardiac magnetic resonance (CMR)-proven myocarditis shortly after vaccination) (seriousness criterion medically significant). At the time of the report, MYOCARDITIS (Cardiac magnetic resonance (CMR)-proven myocarditis shortly after vaccination) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Ejection fraction (Unknown-> 55%): 58% (normal) 58%. In 2021, Electrocardiogram: abnormal (abnormal) Sinus rhythm with diffuse ST elevation. In 2021, Magnetic resonance imaging heart: abnormal (abnormal) Short-axis views demonstrating increased T2 signal and LGE in the mid wall and subepicardial layer of the mid-posterolateral segment in a patient who received their second SARS-CoV-2 vaccination 6 days earlier. In 2021, SARS-CoV-2 test: negative (Negative) Patient had negative nasopharyngeal SARS-CoV-2 PCR testing. In 2021, Troponin I: 18.94 ng/ml 18.94 ng/mL.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered MYOCARDITIS (Cardiac magnetic resonance (CMR)-proven myocarditis shortly after vaccination) to be possibly related.    Concomitant medications were not provided.  No treatment information was provided.  Patient was within the age range 20-25 years, previously healthy with no infectious prodrome.  The symptoms of the patient at presentation included pleuritic and positional chest pain, chills, myalgias, and subjective fever. Patient did not develop any other complications.  Author concluded that although the clinical presentation, CMR findings, and temporal association strongly suggest the possibility of vaccine associated myocarditis in our 6 patients, we cannot conclude definitively that COVID-19 vaccine was causative or that other etiologies for myocarditis can be definitively excluded in our patients. Nevertheless, clinicians should be suspicious of myocarditis in recently vaccinated patients with symptoms consistent with this diagnosis.  Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.