Age: 60.0
Sex: M
Vaccine: COVID19
Symptoms: Joint range of motion decreased, Vaccination site movement impairment, Vaccination site nerve damage, Vaccination site pain
Clinical narrative: extremely painful left arm which was the injection site; the vaccine may have hit a nerve/injection did something to the bicep nerve or deltoid; limited use of that arm; could not curl his arm; This is a spontaneous report from a contactable pharmacist via a Pfizer sponsored program. A 60-year-old male patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection), via unspecified route of administration, administered in the left arm on 03Apr2021 (batch/lot number and expiry date unknown) at 60 years of age as dose 1, single for covid-19 immunization. The patient's medical history and concomitant medications were none. The pharmacist informed that the patient experienced extremely painful left arm which was the injection site and was improving but was still painful. The pharmacist informed that the patient also had limited use of that arm. The pharmacist informed that after the patient got his vaccine his arm was extremely painful, and he had limited use of his arm. The patient went to the doctor and a neurologist who said it might take him a year to get back full use of his arm; they were thinking the vaccine may have hit a nerve. The pharmacist was asking if the patient can receive the second dose of the vaccine in his butt/glute. The pharmacist informed that the pain in the patient's arm began the evening of his vaccine, 03Apr2021. It has continued and has improved some over time. The pharmacist informed that the limited use of arm was on 03Apr2021 (also reported "didn't have limited use of his arm"). The pain got so bad that the patient contacted his physician who sent him to a neurologist. The pharmacist informed that the patient had some work done on his shoulder and the neurologist thought the injection did something to the bicep nerve or deltoid. The pharmacist informed that the patient worked out a lot and for about 2 to 3 days after the vaccine (Apr2021) he could not curl his arm. The pharmacist informed that it has improved, his arm was probably back to 20 % of what it was before the vaccine. The outcome of the event the vaccine may have hit a nerve/injection did something to the bicep nerve or deltoid was unknown, while recovering for the rest of the events. The pharmacist informed that the event limited use of arm was related. The pharmacist informed that the patient wanted to get the second dose of the vaccine and wanted to know it can it be administered in the gluteal muscle. The pharmacist was advised from document states "that for adults age 19 years and older, the deltoid muscle is preferred for routine intramuscular vaccinations. The anterolateral thigh also can be used."  The lot number for the vaccine, bnt162b2, was not provided and will be requested during follow up.; Sender's Comments: Based on the available information in the case, the causal association between the events vaccination site pain, vaccination site nerve damage, vaccination site movement impairment, joint range of motion decreased and the suspect drug BNT162B2 cannot be excluded. The case will be reassessed once new information is available.  The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.