Sex: F
Vaccine: COVID19
Symptoms: Inflammation, Pruritus, Rash, Vaccination site bruising
Clinical narrative: The caller stated that in the evening she noticed an area of inflammation on the upper arm; itching; There's still a noticeable rash there; caller have a bruise, a small bruise; This spontaneous case was reported by a patient and describes the occurrence of INFLAMMATION (The caller stated that in the evening she noticed an area of inflammation on the upper arm), PRURITUS (itching), VACCINATION SITE BRUISING (caller have a bruise, a small bruise) and RASH (There's still a noticeable rash there) in an elderly female patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis.     No Medical History information was reported.    On 11-Sep-2024, the patient received dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (unknown route) 1 dosage form. On 11-Sep-2024, the patient experienced INFLAMMATION (The caller stated that in the evening she noticed an area of inflammation on the upper arm), PRURITUS (itching) and RASH (There's still a noticeable rash there). In September 2024, the patient experienced VACCINATION SITE BRUISING (caller have a bruise, a small bruise). At the time of the report, INFLAMMATION (The caller stated that in the evening she noticed an area of inflammation on the upper arm), PRURITUS (itching) and RASH (There's still a noticeable rash there) had not resolved and VACCINATION SITE BRUISING (caller have a bruise, a small bruise) outcome was unknown.        For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Unknown), the reporter did not provide any causality assessments.   No concomitant medication was reported. Suspect product dosage text was reported as unknown. It was reported that the patient stated that in the evening she noticed an area of inflammation on the upper arm and grew in size like 3x4 inches and caller stated that she actually still had it and it's only slightly improved and started itching a couple of days ago. Patient stated that she knows that both vaccines tweak the MRNa component to reflect the changes in the virus mutations but was wondering if Moderna was using a different adjuvant or something else that perhaps caller were allergic to because it didn't happen before. The caller's husband knows anatomy because husband was in the medical field and said that the pharmacy staff instead of injecting it into the thickest part of the deltoid, the pharmacy staff injected it in the thinnest part and, husband thought that the pharmacy staff hit like a capillary because patient have a bruise, a small bruise where the pharmacy staff did the injection which the patient have never had before with any vaccine in her life and was wondering if the location of the administration of the vaccine or the placement in the muscle makes a difference in any side effects. The patient also added that the effects started on that evening and then the next day it was a lot worse, and caller still had it after all this time. The area of inflammation no longer feels warm to touch, but it was still noticeable. There was still a noticeable rash there. No treatment medication was reported.   This case was linked to US-MODERNATX, INC.-MOD-2024-774093 (E2B Linked Report).; Sender's Comments:  US-MODERNATX, INC.-MOD-2024-774093:same patient but Different dose