Age: 74.0
Sex: M
Vaccine: COVID19
Symptoms: Urticaria
Clinical narrative: broke out into hives around 2 days after the vaccine was administered. The hives present themselves on both arms; This spontaneous case was reported by a patient and describes the occurrence of URTICARIA (broke out into hives around 2 days after the vaccine was administered. The hives present themselves on both arms) in a 74-year-old male patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (batch no. 3042388) for COVID-19 prophylaxis.     Previously administered products included for Product used for unknown indication: Pfizer (Dose 6), Pfizer (Dose 5), Pfizer (Dose 1), Pfizer (Dose 3), Pfizer (Dose 2) and Pfizer (Dose 4). Past adverse reactions to the above products included No adverse effect with Pfizer, Pfizer, Pfizer, Pfizer, Pfizer and Pfizer. Concurrent medical conditions included Reaction to monosodium glutamate (spice in food) and Penicillin allergy (hives reaction, patient will get z-pack whenever needs a medication.).    On 07-Sep-2024, the patient received eighth dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (unknown route) .5 milliliter. In September 2024,  after starting mRNA-1273.712 (SPIKEVAX 2024-2025 PFS), the patient experienced URTICARIA (broke out into hives around 2 days after the vaccine was administered. The hives present themselves on both arms). The patient was treated with HYDROCORTISONE at a dose of 1 UNK. At the time of the report, URTICARIA (broke out into hives around 2 days after the vaccine was administered. The hives present themselves on both arms) had not resolved.        For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were reported. The Patient didn't receive any other vaccines in the 4 weeks prior to COVID-19 vaccine.  Patient stated the symptoms were same both times and broke out into hives around 2 days after the vaccine was administered. The hives present themselves on both arms. In the last year the symptoms lasted 10 days to 2 weeks. Patient stated that used 'the same kind of cream take for poison ivy'- hydrocortisone 1%. Patient applied the cream on and then wraps the arms in gauze bandages.   Patient does this to prevent additional irritation and to help in the healing process. If it doesn't do this, the friction on the hives causes pain and discomfort. Patient cannot wear short sleeve shirts, and it was ugly and currently still has them on the arms and said they were almost gone. It was stated that they're a little less than last year and doesn't know if it was building up an immunity to the vaccine in terms of the hives. Patient reporting these side effects to the pharmacist and was advised to report to Moderna as it is valuable for us to know. Patient was nervous about getting future Moderna vaccines at pharmacy because of the hive symptoms.  No treatment medications were reported.   This case was linked to US-MODERNATX, INC.-MOD-2024-774319, US-MODERNATX, INC.-MOD-2024-774320 (E2B Linked Report).   Most recent FOLLOW-UP information incorporated above includes: On 19-Sep-2024: Live non-significant follow up received: reference numbers were added.; Sender's Comments:  US-MODERNATX, INC.-MOD-2024-774319:Same Patient Different product (Spikevax 2023-2024) US-MODERNATX, INC.-MOD-2024-774320:many people case