Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Gene mutation, Investigation, Lip pain, Neuropathy peripheral, Skin exfoliation
Clinical narrative: has neuropathy in both her feet; had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A; She had sores in her mouth and lips ever since receiving both doses of the vaccine.; She had sores in her mouth and lips ever since receiving both doses of the vaccine.; her nails were peeling at one point which has never happened before but has since stopped.; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 60-year-old female patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose Number:01), for Covid-19 Immunization, reaction(s): "it feels like electrical jolts/ also had electrical jolts a week later", "She said she had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A", "She said it started out with her left middle finger going numb on one side", "her nose and the roof of her mouth and tongue started going numb", "She had sores in her mouth and lips ever since receiving both doses of the vaccine", "neuropathy in both her feet", "her nails were peeling at one point which has never happened before but has since stopped", "She had sores in her mouth and lips ever since receiving both doses of the vaccine". The following information was reported: NEUROPATHY PERIPHERAL (medically significant), outcome "unknown", described as "has neuropathy in both her feet"; GENE MUTATION (non-serious), outcome "unknown", described as "had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A"; STOMATITIS (non-serious), LIP PAIN (non-serious), outcome "unknown" and all described as "She had sores in her mouth and lips ever since receiving both doses of the vaccine."; SKIN EXFOLIATION (non-serious), outcome "recovered", described as "her nails were peeling at one point which has never happened before but has since stopped.". The patient underwent the following laboratory tests and procedures: investigation: scn11a, notes: positive for a gene mutation called SCN11A; neuropathy, notes: she has neuropathy in both her feet.  Additional information: 61-year-old female consumer said she has already received both doses of the Pfizer-BioNTech Covid-19 Vaccine. She said that a couple of days after her 1st dose, she had some reactions. She also said that the rest of the reactions started a month after her 1st dose. She said both her feet are numb and vibrating, and it feels like electrical jolts. She said it started out with her left middle finger going numb on one side. It also had electrical jolts a week later. She said her right fingertips were going numb as well. She got tested and was told she has neuropathy in both her feet. And while waiting for the nerve conduction test, her nose and the roof of her mouth and tongue started going numb. She had sores in her mouth and lips ever since receiving both doses of the vaccine. She said she had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A. She also mentioned that her nails were peeling at one point which has never happened before but has since stopped. Consumer said she was 60 years old when the side effects happened, but she is 61 years old right now. With that, consumer wants to know if it is still safe for her to get the booster dose. She wants to know if this is the maximum amount of neuropathy she'll get from the vaccine or if the booster dose would exacerbate her neuropathy and make it worse. She said she is not the only person who is going through the same reaction.  The lot number for bnt162b2 was not provided and will be requested during follow up.