Age: 57.0
Sex: F
Vaccine: VARZOS
Symptoms: Nausea, Pain, Pain in extremity, Pain in jaw, Vaccine positive rechallenge
Clinical narrative: swelling glands in under my right arm and neck; Achiness; Stayed in bed; Feeling extremely nauseated; Jaw hurt really bad; Headache/ head is killing me; chills; lost 6 pounds since second dose administration; Feeling crappy/ feeling worst; Arm hurt really bad; This non-serious case was reported by a consumer via call center representative and described the occurrence of pain in arm in a 57-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Shingrix with an associated reaction of pain in extremity (1st dose received on 6th June 2023, refer case US2023AMR116960.).   On 17-AUG-2023, the patient received the 2nd dose of Shingrix (right arm). In AUG-2023, less than a day after receiving Shingrix, the patient experienced pain in arm (Verbatim: Arm hurt really bad), chills (Verbatim: chills), feeling abnormal (Verbatim: Feeling crappy/ feeling worst) and weight loss (Verbatim: lost 6 pounds since second dose administration). On 18-AUG-2023, the patient experienced jaw pain (Verbatim: Jaw hurt really bad), headache (Verbatim: Headache/ head is killing me) and nausea (Verbatim: Feeling extremely nauseated). On 19-AUG-2023, the patient experienced bedridden (Verbatim: Stayed in bed). On 25-AUG-2023, the patient experienced swollen glands (Verbatim: swelling glands in under my right arm and neck) and pain (Verbatim: Achiness).  Rechallenge with Shingrix was positive. On 20-AUG-2023, the outcome of the bedridden was resolved (duration 1 day). The outcome of the pain in arm, swollen glands, jaw pain, headache, chills, pain, feeling abnormal, nausea and weight loss were not resolved.   It was unknown if the reporter considered the pain in arm, swollen glands, jaw pain, headache, chills, pain, feeling abnormal, nausea, weight loss and bedridden to be related to Shingrix.     It was unknown if the company considered the pain in arm, swollen glands, jaw pain, headache, chills, pain, feeling abnormal, nausea, weight loss and bedridden to be related to Shingrix.   Linked case(s) involving the same patient:  US2023AMR116960   Additional Information: GSK Receipt Date: 25-AUG-2023 The reporter reported that she received Shingrix vaccine on Thursday in her right arm and she woke up at mid night with chills, her arm hurt really bad and felt crappy.  The reporter stated that on 18th August 2023, next day patient had a horrible headache and her jaw hurt really bad and she felt extremely nauseated all day on Friday. On Saturday and Sunday patient was stayed in bed.  The reporter stated that on Monday patient had some relief of symptoms feeling better and noticed she lost 6 pounds since received second dose.  The reporter reported that on Wednesday and Thursday patient was felt worst again and today on Friday patient having all symptoms back again stated that she had chills, her head was killing her, swelling glands in under her right arm and neck and also had achiness. The reporter consented to follow up.; Sender's Comments:  US-GSK-US2023AMR116960:1st dose case, same patient, same reporter