chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 47.0
Sex: F
Vaccine: FLUX
Symptoms: Tremor
Clinical narrative: Received flu shot at approx. 1115 AM on 10-5-2018. At approx. 815 PM that evening, I got shaking chills, my "skin hurt", achy all over body and low grade temp of 100.0. I took ibuprofen 600 mg and fell asleep. I woke up at 215 AM with fever of 104.6. Could hardly walk, severe headache, dizzy and my fingers felt numb. Took TYLENOL 1000 mg and laid on couch. Boyfriend checked on me at 530 AM and fever was down to 103.8. Took additional 600 mg of ibuprofen and stood in a cold shower. I did not want to go to ER, so I went back and laid in bed. Woke up at 9 AM completely drenched and fever down to normal at 98.3. Felt fatigued and weak x 24 hours, but no further elevated temperature. Should have went to ER, but I honestly felt too ill and they would have told me to take the ADVIL and TYLENOL.
Age: 19.0
Sex: F
Vaccine: FLU4
Symptoms: Syncope
Clinical narrative: After receiving vaccine, pt walked away. I was alerted that a customer was on the floor across the aisle (approx 40 feet away). By the time I got there, another customer had revived her.   Apparently, she had fainted (the patient who just received vaccine). I stayed with her for maybe 5 minutes, she remained seated, and we gave her water. After a few more minutes she was completely revived and left with no apparent injuries.
Age: 65.0
Sex: F
Vaccine: FLU3, PNC13
Symptoms: Vaccination site rash
Clinical narrative: RASH NOTED AFTER VACCINATIONS IN LOWER LEFT ARM UNDER SHOT GIVEN. RASH CONTINUED TO GET WORSE. PT DAUGHTER CALLED PHARMACY TO ASK ADVICE AND WAS TOLD TO GO HAVE HER PHYSICIAN EXAM HER TODAY (CALL WAS EARLY AFTERNOON BEFORE MD OFFICE CLOSED).
Age: 18.0
Sex: M
Vaccine: FLU4
Symptoms: Rash erythematous, Rash macular
Clinical narrative: Presents now with blotchy erythematous areas on trunk. ~ 6 areas varying from size of tennis ball to grapefruit. Areas are under both arms, chest and belly. Nothing on back. Pt. had influenza injection at 12:00  given by Medical Assistant. Did not feel any reaction for several hours. Red areas developed about 3-3:30 and increased over next 1 1/2 hours. Pt. decided he should have someone take a look and presented to clinic about 4:45. Benadryl 25 mgs at 5:01 PM. Pt. left at 5:50 feeling much improved. The area on the neck has completely resolved. There was no itching and the other areas affected were lighter. Contacted pt. next am and all had resolved.
Age: 10.0
Sex: F
Vaccine: MENB, MNQ, VARCEL
Symptoms: Pruritus, Vaccination site swelling
Clinical narrative: On 10/10, patient received the 3 vaccines in the oncology clinic. On 10/11, patient developed swelling to the vaccination site on her right arm. Denies pain but c/o itchiness. Patient was monitored in the ER.
Age: 0.83
Sex: M
Vaccine: FLU4
Symptoms: Bronchial hyperreactivity, Oxygen therapy, Respiratory distress
Clinical narrative: Three days later presented with severe respiratory distress with reactive airway disease; oxygen, bronchodilators. Requiring ambulance and ER visit, possibly hospitalization.
Age: 21.0
Sex: F
Vaccine: FLU4
Symptoms: Deafness, Disorientation, Seizure, Syncope
Clinical narrative: Fainting, Convulsions, Disorientation, Brief Loss of Hearing (all lasting about a minute total).
Age: 53.0
Sex: M
Vaccine: FLU4, VARZOS
Symptoms: Chills, Hot flush, Injection site pain, Pain, Pain in extremity
Clinical narrative: Patient reports extreme pain in his left arm about 10 minutes after getting the vaccines. He reported after a day that a fever occurred, body pain, and chills/hot flashes that lasted 2 days.
Age: 53.0
Sex: M
Vaccine: FLU4, VARZOS
Symptoms: Pyrexia
Clinical narrative: Patient reports extreme pain in his left arm about 10 minutes after getting the vaccines. He reported after a day that a fever occurred, body pain, and chills/hot flashes that lasted 2 days.
Age: 61.0
Sex: F
Vaccine: VARZOS
Symptoms: Chills, Diarrhoea, Headache, Pyrexia
Clinical narrative: Patient had severe headache, fever (didn't measure how high), diarrhea, and chills. She stated the began on 10/18/18 and lasted for about 24 hours. When patient was contacted on 10/19/18 she stated she was doing much better.
Age: 34.0
Sex: M
Vaccine: FLU4, FLU4
Symptoms: Pain in extremity
Clinical narrative: Patient complains of pain in the left arm for more than 30 days. She said she can move her arm up and down but have pain in the shoulder if she put her hand in her hip or waist. Patient took ADVIL twice a day, but is not helping with the pain. Rph advised patient to see a medical doctor and get checked for the cause of the pain.
Age: 72.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Injection site erythema, Injection site pain, Injection site rash, Injection site warmth
Clinical narrative: Patient came in on 10/19 asking if the rash on her right arm was normal adverse reaction (it was near the elbow area (it extended from half way between her elbow and her shoulder blade down to her elbow and wrapped almost half way around her arm), which is away from the site of injection). She said she didn't know if it was from the pneumonia shot since she had also received the flu shot in her left arm and started a new medication (Multaq, which made her very sick to her stomach) all at the same time, but she wanted me to report it since there is a very rare occassion of a rash as an adverse reaction to the PNEUMOVAX. She said it was red and warm, but she did not report any itching. She did report she had the soreness at the injection site but no redness at the injection site.
Age: 63.0
Sex: F
Vaccine: FLUC4
Symptoms: Injection site hypoaesthesia
Clinical narrative: Pt called on 10-19-18 in the morning stating that she was feeling "paralysis" "feels like my arm is hanging" of the R arm (site of administration). Which started today on 10-19-18 in the morning after she woke up. I asked if the patient had any other major symptoms. She denied of having any inflammation/swelling near the site of the administration and also denied of having fever. I further advised the patient to seek further treatment by visiting her PCP or visiting a nearby Urgent Care Facility for further examination and clearance and to rule out any other cause of "paralysis" of the R arm. I also advised the patient to follow up with us in next 24-48 hours to see how she was feeling and the status of her complaint. We will also follow-up with the patient in the next 24-48 hours.
Age: 67.0
Sex: M
Vaccine: VARZOS
Symptoms: Herpes zoster
Clinical narrative: Patient reported that he got severe shingles breakouts four days after second dose of SHINGRIX vaccine. Patient went to see medical assistance and was prescribed Valacyclovir 500 to help recover from Shingles.
Age: 63.0
Sex: M
Vaccine: FLU4, PPV
Symptoms: Asthenia, Blood test, Culture, Erythema, Pain
Clinical narrative: Patient spiked fevers, with the highest one marked at 107. Red, sore arm. Achy, weak. Symptoms lasted >7 days. Went to hospital. Had bloodwork and cultures done to rule out other illnesses. Wanted to put patient in an ice bath because of his high fever. Could not determine if this was due to vaccinations or not.
Age: 63.0
Sex: M
Vaccine: FLU4, PPV
Symptoms: Pain in extremity, Pyrexia
Clinical narrative: Patient spiked fevers, with the highest one marked at 107. Red, sore arm. Achy, weak. Symptoms lasted >7 days. Went to hospital. Had bloodwork and cultures done to rule out other illnesses. Wanted to put patient in an ice bath because of his high fever. Could not determine if this was due to vaccinations or not.
Age: 10.0
Sex: M
Vaccine: FLU4
Symptoms: Injection site reaction, Injection site swelling, Injection site warmth, Rash papular
Clinical narrative: Patient reports raised red rash at the injection site slightly larger than an oreo cookie, warm to the touch, and swollen. Patient denies any other symptoms.
Age: 54.0
Sex: M
Vaccine: FLU4, PPV
Symptoms: Injection site swelling, Pyrexia
Clinical narrative: Fever to 103.1. Very swollen arm at injection site and surrounding muscle.
Age: 55.0
Sex: F
Vaccine: PPV
Symptoms: Injection site rash
Clinical narrative: Patient had red rash form in a band around her at the injection site. Patient received antibiotics from a medical doctor on 10/17/18.
Age: 35.0
Sex: M
Vaccine: FLUC4
Symptoms: Eye pain, Fatigue, Pain
Clinical narrative: 10/17, I had body aches specifically more intense in legs and groin. 10/18 I began to notice eye pressure/pain and was unable to wear contacts. 10/19 I was still experiencing eye pain and felt even more intense body aches and exhaustion. I spent half the day in bed. Prior to shot I haven't experienced any sickness or body problems (other than acid reflux) in over six months.
Age: 71.0
Sex: M
Vaccine: PNC13
Symptoms: Chills, Hypersensitivity, Pain, Rash erythematous, Vaccination site rash
Clinical narrative: Pt's wife called on 10/17/18 stating that the patient was having chills and slight body aches. We advised her to give him an OTC pain reliever such as TYLENOL. They came in to the store 10/19/18 (today) stating that patient is having an allergic reaction to the PREVNAR vaccine. We stepped into the consultation room so I could see pt's arm. Pt's had a large red rash that extended down towards his elbow. He said he had already taken BENADRYL. I advised pt to go to a minor med as his rash looked like an allergic reaction. Later tonight, we received Rxs for antibiotic, steroid pack and BENADRYL. As of this report, he has not returned to pick them up.
Age: 61.0
Sex: F
Vaccine: FLU4, TDAP, VARZOS
Symptoms: Injection site pruritus, Injection site swelling, Rash
Clinical narrative: About 36-48 hours after receiving these vaccines, patient reports swelling and itching at the injection site for SHINGRIX (left upper arm). She said that one day after this reaction, she noted a diffuse rash on both lower arms. She reports that it does not itch.
Age: 81.0
Sex: M
Vaccine: PNC13
Symptoms: Haemorrhage
Clinical narrative: PATIENT CLAIMS STILL BLEEDING FROM THE INJECTION SITE, INFORMED PATIENT TO REACH OUT TO THEIR DOCTOR AND EXPLAINED THE LOCATION OF THE BLEEDING WAS NOT WHERE HE WAS VACCINATED, IT COULD BE DUE TO SOME OTHER FACTORS.
Age: 81.0
Sex: F
Vaccine: VARZOS
Symptoms: Anaphylactic reaction, Dyspnoea, Swollen tongue
Clinical narrative: Patient developed a severe anaphylactic allergic reaction following the 2nd dose of SHINGRIX. The patient reported it started as a moderate tongue swelling that she didn't think too much of. She initially started to ice the tongue, but in time it only got worse and she needed to call for the paramedics to take her to the hospital as it swelled excessively and started to affect her breathing. The hospital course is unknown as this was relayed to us by the coordinator at her place of residence. The patient has since been discharged is said to be doing fine. It was also noted that the patient experienced a mild tongue swelling following her first SHINGRIX dose and didn't think much of it, and as a result was not reported to us prior to administering the 2nd dose. We only learned about this following her severe reaction.
Age: 38.0
Sex: F
Vaccine: FLU4
Symptoms: Chest pain, Feeling cold, Lip swelling, Paraesthesia, Pyrexia
Clinical narrative: Wheezing, chest pain, chills within 3 hrs after shot, next morning swollen upper lip, low grade fever. Tingling hands and feet.
Age: 38.0
Sex: F
Vaccine: FLU4
Symptoms: Wheezing
Clinical narrative: Wheezing, chest pain, chills within 3 hrs after shot, next morning swollen upper lip, low grade fever. Tingling hands and feet.
Age: 67.0
Sex: F
Vaccine: PPV
Symptoms: Asthenia, Back injury, Body temperature increased, Dizziness, Fall
Clinical narrative: The arm they received the injection site became very painful and I had a limited mobility in it for two days. I ran a temperature starting a few hours after having the shot and developed blisters on my lips from the fever. I also felt nauseous and weak. It was impossible to sleep for two nights due to the pain. This morning 10/19/18, while taking a shower I got very nauseous and dizzy and ended up falling in the shower hitting my head lower back and entering my ankle. I was in the ER for five hours. In the ER they looked at the red skin from my pneumonia shot and think it might be cellulitis. I have never felt so sick in my life after having a vaccine.
Age: 67.0
Sex: F
Vaccine: PPV
Symptoms: Head injury, Injected limb mobility decreased, Injection site pain, Joint injury, Lip blister
Clinical narrative: The arm they received the injection site became very painful and I had a limited mobility in it for two days. I ran a temperature starting a few hours after having the shot and developed blisters on my lips from the fever. I also felt nauseous and weak. It was impossible to sleep for two nights due to the pain. This morning 10/19/18, while taking a shower I got very nauseous and dizzy and ended up falling in the shower hitting my head lower back and entering my ankle. I was in the ER for five hours. In the ER they looked at the red skin from my pneumonia shot and think it might be cellulitis. I have never felt so sick in my life after having a vaccine.
Age: 67.0
Sex: F
Vaccine: PPV
Symptoms: Malaise, Nausea, Sleep disorder
Clinical narrative: The arm they received the injection site became very painful and I had a limited mobility in it for two days. I ran a temperature starting a few hours after having the shot and developed blisters on my lips from the fever. I also felt nauseous and weak. It was impossible to sleep for two nights due to the pain. This morning 10/19/18, while taking a shower I got very nauseous and dizzy and ended up falling in the shower hitting my head lower back and entering my ankle. I was in the ER for five hours. In the ER they looked at the red skin from my pneumonia shot and think it might be cellulitis. I have never felt so sick in my life after having a vaccine.
Age: 61.0
Sex: M
Vaccine: VARZOS
Symptoms: Chills, Fatigue, Headache, Influenza like illness, Injection site pain
Clinical narrative: (This is my second dose of SHINGRIX; I had a very similar adverse reaction to the first dose on 4/17/18. Initial reaction was not reported.) There was no reaction for 10 hours until I went to bed. Approximately 10-12 hours after the injection, I woke up with flu-like symptoms, which increased in severity over the next 12 hours and then dissipated. The symptoms included: chills and shivering, mild fever, very severe muscle aches throughout my body, headaches, mild nausea. Soreness in the arm at the site of the injection was present (although not in the first 10 hours), but was the least concerning reaction of the above. I did not go to work, stayed in bed most of the day, sleeping, sipping water, ate toast, took 2 ibuprofen. By late afternoon -- 24 hours after the injection -- I was feeling few severe symptoms, but was very fatigued. By evening the most of the symptoms subsided.
Age: 61.0
Sex: M
Vaccine: VARZOS
Symptoms: Loss of personal independence in daily activities, Myalgia, Nausea, Pyrexia
Clinical narrative: (This is my second dose of SHINGRIX; I had a very similar adverse reaction to the first dose on 4/17/18. Initial reaction was not reported.) There was no reaction for 10 hours until I went to bed. Approximately 10-12 hours after the injection, I woke up with flu-like symptoms, which increased in severity over the next 12 hours and then dissipated. The symptoms included: chills and shivering, mild fever, very severe muscle aches throughout my body, headaches, mild nausea. Soreness in the arm at the site of the injection was present (although not in the first 10 hours), but was the least concerning reaction of the above. I did not go to work, stayed in bed most of the day, sleeping, sipping water, ate toast, took 2 ibuprofen. By late afternoon -- 24 hours after the injection -- I was feeling few severe symptoms, but was very fatigued. By evening the most of the symptoms subsided.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Pain, Pain in extremity
Clinical narrative: Patient stated on 10/19/18 over the phone that after the IMZ on 10/18/18 she noticed her arm hurting more and more as the day  progressed to the point of it hurting with any movement. Patient did state that she could still function in her normal daily routine. Patient is going to wait and see if the pain subsides over the next few days.
Age: 15.0
Sex: M
Vaccine: VARCEL
Symptoms: Blood test normal, Muscle fatigue, Pain in extremity, Tremor
Clinical narrative: Noted tremors in hands and increased pain and fatigue in upper extremity. Limited patient's ability to do school work or play classical guitar due to fatigue and pain in arms. Still continues 5 months later.
Age: 0.58
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC13, RV5
Symptoms: Abdominal pain, Crying, Electroencephalogram, Hypersomnia, Infantile spasms
Clinical narrative: Swollen, redness at injection site (right thigh). Fever (101 plus). Restless. Then excessive sleep. Inconsolable, Crying lasting 12 plus hours. Seizures/infantile spasms. Rigidness, abdominal pain, diarrhea, lethargic.
Age: 0.58
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC13, RV5
Symptoms: Injection site erythema, Injection site swelling, Lethargy, Muscle rigidity, Pyrexia
Clinical narrative: Swollen, redness at injection site (right thigh). Fever (101 plus). Restless. Then excessive sleep. Inconsolable, Crying lasting 12 plus hours. Seizures/infantile spasms. Rigidness, abdominal pain, diarrhea, lethargic.
Age: 0.58
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC13, RV5
Symptoms: Restlessness, Seizure
Clinical narrative: Swollen, redness at injection site (right thigh). Fever (101 plus). Restless. Then excessive sleep. Inconsolable, Crying lasting 12 plus hours. Seizures/infantile spasms. Rigidness, abdominal pain, diarrhea, lethargic.
Age: 13.0
Sex: M
Vaccine: FLU4
Symptoms: Feeling cold, Laboratory test normal, Pallor, Tremor, Visual impairment
Clinical narrative: Patient was given flu vaccination. About 5 minutes later, patient stated that vision was black, he looked pale, shaking, and cold to touch. 911 was called. Patient went to ER. No findings on lab results and no diagnosis was given. Parent was advised to follow-up with PCP if any new symptoms arise.
Age: 67.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Headache, Injected limb mobility decreased, Nausea, Pain in extremity, Peripheral swelling
Clinical narrative: Pt received FLUZONE HD/PNEUMOVAX on 10/15/18 and started experiencing pain in right arm, nausea, headache in the evening around 6 PM. Pt had heat rash on arm that swelled outwards horizontally and could not lift arm. She took an opiate pain-killer to help with the pain. The arm continued to worsen in the interim. On the 3rd day, pt had a doctor's appointment and MD prescribed BACTRIM DS as it looked like a skin infection upon physical examination. Pt also given a probiotic. Pt's arm is now feeling much better on 10/19/18. Pain and redness has receded, and skin color is yellow indicating healing.
Age: 67.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Rash, Skin warm, Yellow skin
Clinical narrative: Pt received FLUZONE HD/PNEUMOVAX on 10/15/18 and started experiencing pain in right arm, nausea, headache in the evening around 6 PM. Pt had heat rash on arm that swelled outwards horizontally and could not lift arm. She took an opiate pain-killer to help with the pain. The arm continued to worsen in the interim. On the 3rd day, pt had a doctor's appointment and MD prescribed BACTRIM DS as it looked like a skin infection upon physical examination. Pt also given a probiotic. Pt's arm is now feeling much better on 10/19/18. Pain and redness has receded, and skin color is yellow indicating healing.
Age: 45.0
Sex: F
Vaccine: FLU4
Symptoms: Bursitis, Injected limb mobility decreased, Injection site pain, Shoulder injury related to vaccine administration, Ultrasound scan
Clinical narrative: Patient has been feeling pain  and limited arm movement on her arm since she got the shot x 5 weeks. She went to see her md, md said she has bursitis, it's SIRVA. She will be getting cortisone shot next week, and maybe physical therapy.
Age: 64.0
Sex: F
Vaccine: FLUC4
Symptoms: Eye swelling, Pharyngeal oedema, Swelling face
Clinical narrative: Swelling of eyes, face and throat.
Age: 55.0
Sex: F
Vaccine: FLU4
Symptoms: Loss of personal independence in daily activities, Pain in extremity, Sleep disorder
Clinical narrative: I have had extreme right arm pain for four weeks since the flu shot was administered. I have constant pain. I struggle to dress and shower in the morning. The pain is somewhat alleviated with round the clock ibuprofen and ice, but never completely. I struggle to sleep at night due to the pain. It has been a month and there is no sign of the pain dissipating.
Age: 66.0
Sex: M
Vaccine: FLU3
Symptoms: Blood glucose decreased, Feeling abnormal, Loss of consciousness, Pallor, Pulse abnormal
Clinical narrative: Around 9:00 pm. Syncopal episode. Lasted approximately 30 sec to 1:00 minute. Onset over about 5 minutes. Felt "fuzzy headed", vision got narrow. Then passed out. Leaning on counter at time talking to people. Normal day. No increased physical activity. No dehydration. Reported by people there that I was white as a sheet with weak pulses. Woke up knew everyone there taking care of me. Blood glucose 77. No confusion other than the event. OK after event.
Age: 66.0
Sex: M
Vaccine: FLU3
Symptoms: Syncope, Visual impairment
Clinical narrative: Around 9:00 pm. Syncopal episode. Lasted approximately 30 sec to 1:00 minute. Onset over about 5 minutes. Felt "fuzzy headed", vision got narrow. Then passed out. Leaning on counter at time talking to people. Normal day. No increased physical activity. No dehydration. Reported by people there that I was white as a sheet with weak pulses. Woke up knew everyone there taking care of me. Blood glucose 77. No confusion other than the event. OK after event.
Age: 84.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Acne, Blister, Rash
Clinical narrative: Patient states she ended up having shingle-like reaction about 2 weeks later. Down her arm and back. Dr. prescribed VALTREX and prednisone.
Age: 84.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Rash vesicular
Clinical narrative: Patient states she ended up having shingle-like reaction about 2 weeks later. Down her arm and back. Dr. prescribed VALTREX and prednisone.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Acute respiratory distress syndrome, Alanine aminotransferase increased, Aspartate aminotransferase increased, Asthenia, Bilirubin conjugated increased
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Blood albumin normal, Blood alkaline phosphatase normal, Blood bilirubin increased, Blood lactate dehydrogenase increased, Blood urine present
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Bradycardia, Cardio-respiratory arrest, Chromaturia, Death, Diarrhoea
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Fatigue, Haematuria, Haemoglobin decreased, Haptoglobin abnormal, Hyperbilirubinaemia
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Hypotension, Life support, Malaise, Nausea, Packed red blood cell transfusion
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Protein total decreased, Pyrexia, Resuscitation, Specific gravity urine normal, Urine ketone body absent
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 47.0
Sex: M
Vaccine: FLU4
Symptoms: Urobilinogen urine increased, Vomiting, White blood cell count, White blood cell count increased
Clinical narrative: A 47 year old male with history of HTN, obesity, hyperlipidemia, obstructive sleep apnea, depression and anxiety, presents to ER on 10/12/18 with chief complaints of fatigue, weakness and hematuria x 1 day. Pt reported symptoms began after getting the flu shot the day prior. 1 episode of diarrhea in ED but none at home. Returned from 5 week trip, about 3 weeks prior to presentation. He received a flu vaccine immediately prior to the onset of his Sx and associates his Sx with this event. He reported that following said flu vaccination, he began to feel ill with fatigue and nausea/vomiting. No other medication changes. GI was consulted and felt that his unconjugated hyperbilirubinemia was not due to biliary causes. His hemolysis labs (haptoglobin and LDH) returned positive. Heme/onc was consulted. His Hbg downtrended 12->  7.7->  4.9, and he was noted to spike fever on 10/14 prior to his significantly reduced Hb at 12:30 am. He received 2UPRBC with f/u Hb to 6.9. WBC trended up from 15 (PMN 12)-> 20.38 (PMN 17.39)-> 22.5 (PMN 18.93)-> 25.2 (PMN 55.67)->  29.02 (PMN 27.22). Bilirubin total (with indirect predominance throughout): 15.5->  19.5->  23. Patient initially stabilized with steroids, and determination was made to limit transfusion to keep Hbg greater than 6 to prevent worsening hemolysis. However, at approximately  23:00 10/14/18, patient had acute respiratory distress associated with bradycardia and hypotension, and then suffered cardiopulmonary arrest. He underwent multiple rounds of CPR and ACLS. Patient ultimately expired.
Age: 10.0
Sex: M
Vaccine: FLU4
Symptoms: Asthenia, Myalgia, Pyrexia
Clinical narrative: Temp. to 104. Fever greater than 48 degree - not sure if resolved yet. Myalgias. Sensation of weakness but fine when up moving.
Age: 83.0
Sex: M
Vaccine: FLUA3
Symptoms: Immediate post-injection reaction, Injection site bruising, Injection site pruritus, Injection site swelling, Local reaction
Clinical narrative: Immediate local reaction: arm (inj. site) swelled up and slightly bruised. Mild itch for few mins. No trouble breathing. Pt. refused BENADRYL. Iced site and kept pt. here for 45 mins to 1 hour. Swelling slowly went down. Pt. had no one to drive him home. Offered to have mgr. drive home, pt. refused. Said he felt fine and didn't want to take any OTC to help w/RXN. Requested pt. to call when he got home and he did. Said swelling cont. to go down and he felt fine. Called pt. 10/19/2018 for F/U, said swelling gone just bruised.
Age: 4.0
Sex: F
Vaccine: DTAP
Symptoms: Injection site erythema, Injection site swelling, Urticaria
Clinical narrative: Hives all over body (arms and face). Hives began on left arm and she had swelling and redness at the injection site. Hives came and went for 3 days.
Age: 54.0
Sex: F
Vaccine: FLU4
Symptoms: Musculoskeletal pain, Product administered at inappropriate site
Clinical narrative: IM injection upper arm. Sore shoulder 12 days, undergoing PT therapy, patient suspects injection into bursa.
Age: 36.0
Sex: F
Vaccine: UNK
Symptoms: Erythema, Headache, Injection site erythema, Injection site induration, Injection site warmth
Clinical narrative: Fever up to 102 degree F on 10/15/18 about 2100. Had fever, headache, body aches, and nausea until 10/17/18. Continued until MD gave me Prednisone 20mg. Systemic reaction then stopped, but arm continued to be red and itchy. (L) arm injection site became hard, red, and hot to touch. Site was about the size of a softball at the time, from Monday until Wednesday night.
Age: 36.0
Sex: F
Vaccine: UNK
Symptoms: Nausea, Pain, Pruritus, Pyrexia
Clinical narrative: Fever up to 102 degree F on 10/15/18 about 2100. Had fever, headache, body aches, and nausea until 10/17/18. Continued until MD gave me Prednisone 20mg. Systemic reaction then stopped, but arm continued to be red and itchy. (L) arm injection site became hard, red, and hot to touch. Site was about the size of a softball at the time, from Monday until Wednesday night.
Age: 59.0
Sex: F
Vaccine: FLUR4, HEPA
Symptoms: Injection site pruritus, Injection site warmth
Clinical narrative: Injection site on left deltoid itchy and warm to the touch. Injection done on 10/1/18. Symptoms started 10/2/18. Patient treated with KEFLEX and MEDROL pack.
Age: 65.0
Sex: F
Vaccine: FLU4, PNC13
Symptoms: Muscle spasms, Muscle tightness
Clinical narrative: Muscle tightening and spasms esp. in muscles of abdomen that patient felt were similar to previous dystonia reaction she had to medication. SXs resolved after a few days.
Age: 47.0
Sex: F
Vaccine: FLUC4
Symptoms: Anxiety, Condition aggravated, Immediate post-injection reaction, Nausea
Clinical narrative: Patient got anxious and nauseated instantly. Was questioned regarding medication. Is taking blood pressure and anti-anxiety - Did not take them this day.
Age: 45.0
Sex: F
Vaccine: FLU4
Symptoms: Chest discomfort, Condition aggravated, Diarrhoea, Dyspnoea, Eye swelling
Clinical narrative: Pt. states approximately 1 hr after Flu vaccine, onset acute diarrhea, vomiting, nausea which lasted 2 days. Later that day, 9/25/18 onset increased SOB/ tightness take breath (hx asthma/seasonal allergies and pt. had stopped allergy Rx after rheumatologist visit as PFT and Chest Xray WNL on 9/24/18) and restarted using inhalers. Then 9/26/18 onset hives over body, up face and itching, swelling eyelids and external eyes. Pt thought from Clindamycin at 1st as just started use on face 9/24/18. PMD gave ATARAX for allergies 10/2/18 then PMD gave PO Prednisone taper on 10/3/18. Dr gave KENALOG shot on 10/8/18 and PA (dermatologist) told pt didn't think it was contact dermatitis on 10/8/18 and said maybe due to flu shot. Pt told EH of rxn 10/9/18 and at that time said had rxn to Flu shot 10 yrs ago, but had not said before received Flu shot at EH. Seen in EH 10/10/18.
Age: 45.0
Sex: F
Vaccine: FLU4
Symptoms: Nausea, Swelling of eyelid, Urticaria, Vomiting
Clinical narrative: Pt. states approximately 1 hr after Flu vaccine, onset acute diarrhea, vomiting, nausea which lasted 2 days. Later that day, 9/25/18 onset increased SOB/ tightness take breath (hx asthma/seasonal allergies and pt. had stopped allergy Rx after rheumatologist visit as PFT and Chest Xray WNL on 9/24/18) and restarted using inhalers. Then 9/26/18 onset hives over body, up face and itching, swelling eyelids and external eyes. Pt thought from Clindamycin at 1st as just started use on face 9/24/18. PMD gave ATARAX for allergies 10/2/18 then PMD gave PO Prednisone taper on 10/3/18. Dr gave KENALOG shot on 10/8/18 and PA (dermatologist) told pt didn't think it was contact dermatitis on 10/8/18 and said maybe due to flu shot. Pt told EH of rxn 10/9/18 and at that time said had rxn to Flu shot 10 yrs ago, but had not said before received Flu shot at EH. Seen in EH 10/10/18.
Age: 18.0
Sex: F
Vaccine: MMRV
Symptoms: Product administered to patient of inappropriate age
Clinical narrative: Instructed by CDC to report as pt was given this vaccine, which is meant for 12 and younger.
Age: 71.0
Sex: F
Vaccine: PPV
Symptoms: Injection site erythema, Injection site pain, Injection site rash
Clinical narrative: Adverse reaction started the day the vaccine was administered. The vaccine was given in the left arm and the bicep was red with a profound rash that covered the front of the arm. There was a shooting pain that went from the shoulder to the elbow. Patient called her doctor and the doctor recommended BENADRYL. The patient took one BENADRYL per day for 3 days then presented to the pharmacy to discuss what to do further for the rash. The pain had subsided and the rash improved by the end of day 3.
Age: 12.0
Sex: F
Vaccine: MNQ
Symptoms: Crying, Headache
Clinical narrative: Severe headache crying hysterically.
Age: 48.0
Sex: M
Vaccine: FLU4
Symptoms: Blood pressure increased, Chest X-ray, Chest discomfort, Electrocardiogram, Facial pain
Clinical narrative: Flu shot administered around 5pm. 10/18/18 patient experienced symptoms of bilateral facial pain, chest tightness, increased heart rate and blood pressure and bloodshot eyes around 9pm w/symptoms peaking at 11:15pm when they reported to ER.
Age: 48.0
Sex: M
Vaccine: FLU4
Symptoms: Heart rate increased, Laboratory test, Ocular hyperaemia
Clinical narrative: Flu shot administered around 5pm. 10/18/18 patient experienced symptoms of bilateral facial pain, chest tightness, increased heart rate and blood pressure and bloodshot eyes around 9pm w/symptoms peaking at 11:15pm when they reported to ER.
Age: 28.0
Sex: M
Vaccine: FLU4
Symptoms: Blood glucose, Blood pressure measurement, Heart rate, Loss of consciousness
Clinical narrative: Loss of consciousness for approximately 10 seconds after vaccine. Paramedics called for vitals all came back normal.
Age: 38.0
Sex: M
Vaccine: FLU4
Symptoms: Loss of consciousness, Pallor, Syncope
Clinical narrative: Pt. experienced vasovagal syncope. After administration, pt. became pale and lost consciousness for approximately 5 seconds. He became responsive almost immediately, was given juice and allowed to rest.
Age: 64.0
Sex: F
Vaccine: VARZOS
Symptoms: Pain, Pyrexia, Swelling
Clinical narrative: Patient experienced excessive swelling for one week. Had soreness for 2 weeks. Three days worth of fever: Day 1 (admin. Date) 103 degrees F, then between 101 F and 102 F for Day and Day 3.
Age: 59.0
Sex: F
Vaccine: FLU4, TDAP
Symptoms: Ear pain, Eye burns, Eye pain, Headache, Lacrimation increased
Clinical narrative: Woke up following day with pain in right jaw, ear, eye and head and gland. Dull constant pain on right side. Eye is watery and burning. One week of antibiotics did not change condition at all.
Age: 59.0
Sex: F
Vaccine: FLU4, TDAP
Symptoms: Lymph node pain, Pain in jaw
Clinical narrative: Woke up following day with pain in right jaw, ear, eye and head and gland. Dull constant pain on right side. Eye is watery and burning. One week of antibiotics did not change condition at all.
Age: 76.0
Sex: M
Vaccine: VARZOS
Symptoms: Injection site pain
Clinical narrative: Pain at site of injection.
Age: 14.0
Sex: M
Vaccine: FLU4
Symptoms: Pyrexia, Vomiting
Clinical narrative: Shot given @ 1229. Emesis at 1300. Fever of 102.4 at 1840.
Age: 11.0
Sex: M
Vaccine: FLU4, HPV9, MNQ, TDAP
Symptoms: Abdominal pain, Abdominal tenderness, Activated partial thromboplastin time normal, Alanine aminotransferase increased, Amylase normal
Clinical narrative: Rash - The afternoon of Friday, October 12 he developed a rash that his mom said looked like hives on his chest. Over the next few days, this urticarial rash spread down his abdomen, then spread to his face, and then spread down his legs. Over the past few days, it has transitioned into a generalized redness of the skin. She says the skin feels warm and is irritated. The rash was been consistently itchy. On exam the rash is warm to touch area of erythema and macular rash on right lower arm and left upper arm with lighter diffuse papules and macules on background of erythematous skin of lower extremities that has persisted over five days. No pustules, no papules, no vesicles. Flushing redness across much of back that improved over several days. Erythematous blanching patches over nasal bridge and cheeks. Does have periorbital erythema which mom says is not his baseline. Some dermatographism noted on exam. Severe chest pain and pain in his back. 10/18 /18 - 1 day of low-grade fever (Tmax = 38.4 C) Episodic pain (sometimes severe) to palpation of epigastric area and right lower quadrant of abdomen 1-2 days of dry cough, runny nose, mild pharyngitis, mild abdominal pain. 10/18/2018 - dryness and pealing of lips 10/17/2018 - placed on diphenhydramine 50 mg every 6 hours and lactobacillus rhamnosus probiotic BID 10/18/18 - placed on sucralfate PO QID and ranitidine 75 mg BID 10/19/2018 - placed on ursodiol 300 mg BID Received acetaminophen, ibuprofen, tramadol, morphine, and ondansetron as needed during hospitalization.
Age: 11.0
Sex: M
Vaccine: FLU4, HPV9, MNQ, TDAP
Symptoms: Analgesic drug level therapeutic, Anion gap, Aspartate aminotransferase increased, Atelectasis, Back pain
Clinical narrative: Rash - The afternoon of Friday, October 12 he developed a rash that his mom said looked like hives on his chest. Over the next few days, this urticarial rash spread down his abdomen, then spread to his face, and then spread down his legs. Over the past few days, it has transitioned into a generalized redness of the skin. She says the skin feels warm and is irritated. The rash was been consistently itchy. On exam the rash is warm to touch area of erythema and macular rash on right lower arm and left upper arm with lighter diffuse papules and macules on background of erythematous skin of lower extremities that has persisted over five days. No pustules, no papules, no vesicles. Flushing redness across much of back that improved over several days. Erythematous blanching patches over nasal bridge and cheeks. Does have periorbital erythema which mom says is not his baseline. Some dermatographism noted on exam. Severe chest pain and pain in his back. 10/18 /18 - 1 day of low-grade fever (Tmax = 38.4 C) Episodic pain (sometimes severe) to palpation of epigastric area and right lower quadrant of abdomen 1-2 days of dry cough, runny nose, mild pharyngitis, mild abdominal pain. 10/18/2018 - dryness and pealing of lips 10/17/2018 - placed on diphenhydramine 50 mg every 6 hours and lactobacillus rhamnosus probiotic BID 10/18/18 - placed on sucralfate PO QID and ranitidine 75 mg BID 10/19/2018 - placed on ursodiol 300 mg BID Received acetaminophen, ibuprofen, tramadol, morphine, and ondansetron as needed during hospitalization.
Age: 11.0
Sex: M
Vaccine: FLU4, HPV9, MNQ, TDAP
Symptoms: Basophil count normal, Basophil percentage, Bicuspid aortic valve, Bilirubin conjugated increased, Bilirubin urine present
Clinical narrative: Rash - The afternoon of Friday, October 12 he developed a rash that his mom said looked like hives on his chest. Over the next few days, this urticarial rash spread down his abdomen, then spread to his face, and then spread down his legs. Over the past few days, it has transitioned into a generalized redness of the skin. She says the skin feels warm and is irritated. The rash was been consistently itchy. On exam the rash is warm to touch area of erythema and macular rash on right lower arm and left upper arm with lighter diffuse papules and macules on background of erythematous skin of lower extremities that has persisted over five days. No pustules, no papules, no vesicles. Flushing redness across much of back that improved over several days. Erythematous blanching patches over nasal bridge and cheeks. Does have periorbital erythema which mom says is not his baseline. Some dermatographism noted on exam. Severe chest pain and pain in his back. 10/18 /18 - 1 day of low-grade fever (Tmax = 38.4 C) Episodic pain (sometimes severe) to palpation of epigastric area and right lower quadrant of abdomen 1-2 days of dry cough, runny nose, mild pharyngitis, mild abdominal pain. 10/18/2018 - dryness and pealing of lips 10/17/2018 - placed on diphenhydramine 50 mg every 6 hours and lactobacillus rhamnosus probiotic BID 10/18/18 - placed on sucralfate PO QID and ranitidine 75 mg BID 10/19/2018 - placed on ursodiol 300 mg BID Received acetaminophen, ibuprofen, tramadol, morphine, and ondansetron as needed during hospitalization.