Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Eyelid function disorder, Feeling abnormal, Mobility decreased, Nightmare, Osteoporosis
Clinical narrative: I was like paralyzed I could not move and I could not open my eyes; eyes burning; My eyes and face is swollen; my bone feels like a car throw me away and everything hurts/I could feel every bone; shoulders hurting a lot; My mind was burning/feel like I was burning; my body was in so much pain; bone in my body was like something scanning my body like orange light/could not open my eyes and I feel like I was burning; dreaming in fire and I was getting burned; My eyes and face is swollen; wasn't able to wake up; osteoporosis; could not open my eyes; couldn't not move; This serious case was reported by a consumer via call center representative and described the occurrence of paralysis in a female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Shingrix with an associated reaction of no adverse event (was perfectly fine with the 1st dose, received on an unknown date).   On 07-MAY-2024 03:30, the patient received the 2nd dose of Shingrix. In MAY-2024, an unknown time after receiving Shingrix, the patient experienced paralysis (Verbatim: I was like paralyzed I could not move and I could not open my eyes) (serious criteria GSK medically significant), burning in eyes (Verbatim: eyes burning), facial swelling (Verbatim: My eyes and face is swollen), bone pain (Verbatim: my bone feels like a car throw me away and everything hurts/I could feel every bone), shoulder pain (Verbatim: shoulders hurting a lot), burning sensation (Verbatim: My mind was burning/feel like I was burning), general body pain (Verbatim: my body was in so much pain), feeling abnormal (Verbatim: bone in my body was like something scanning my body like orange light/could not open my eyes and I feel like I was burning), frightening dreams (Verbatim: dreaming in fire and I was getting burned), eye swelling (Verbatim: My eyes and face is swollen), insomnia (Verbatim: wasn't able to wake up), osteoporosis (Verbatim: osteoporosis), eyelid function disorder (Verbatim: could not open my eyes) and mobility decreased (Verbatim: couldn't not move). The outcome of the paralysis, burning in eyes, burning sensation, feeling abnormal, frightening dreams and eyelid function disorder were unknown and the outcome of the facial swelling, bone pain, shoulder pain, general body pain and eye swelling were not resolved and the outcome of the insomnia, osteoporosis and mobility decreased were not reported.   The reporter considered the paralysis, burning in eyes, facial swelling, bone pain, shoulder pain, burning sensation, general body pain, feeling abnormal, frightening dreams, eye swelling, insomnia, osteoporosis, eyelid function disorder and mobility decreased to be possibly related to Shingrix.     The company considered the paralysis, burning in eyes, facial swelling, bone pain, shoulder pain, burning sensation, general body pain, feeling abnormal, frightening dreams, eye swelling, insomnia, osteoporosis, eyelid function disorder and mobility decreased to be possibly related to Shingrix.   Additional Information: GSK Receipt date: 08-MAY-2024 and 09-MAY-2024 The patient self-reported. The patient reported that looks like she got all the side effects of Shingrix. She got 2nd Shingrix yesterday and experienced going to sleep and start dreaming in fire, she was getting burned and not able to wake up or call her husband or say something.  She was like paralyzed, could not move and could not open her eyes and feel like she was burning. Her biggest concern was her eye saying she need to get something wet on her eyes because she going to burn her eyes, at the same time every bone in her body was like something scanning her body like orange light from her head all the way to the bottom.  Something was scanning her bone and she could feel every bone. She had osteoporosis and was in so much pain, her mind was burning, she struggles for she did not know how long but noticed it was turning daylight and she tried to get her arm out of the sheet, and she did, and she started grabbing her husband and she woke him up.  Told him her eyes were burning and she need water, towel wet, her body was in so much pain, but she could not move either.  She put the wet towel, she peed and came back lay down and started calling because she was under sheet and wanted to release those sheets so she could feel better and she called different person there was no Doctor and they could not give a specific thing to do, so calling manufacturer but they were not open so went to sleep.  Today, only difference from her last experience to now, was her bone feels like a car throw her away and everything hurts, his brain feels ok and shoulders hurting a lot.  The patient wanted to know how many days did it takes to go away. Her eyes and face were swollen so she clean her face and put cream to feel better.