Age: 54.0
Sex: F
Vaccine: VARZOS
Symptoms: Immediate post-injection reaction, Injection site urticaria, Mobility decreased, Paraesthesia oral, Pruritus
Clinical narrative: hives / hives at the site and from head to toe; chills; dark urine; tired; felt bad; itching; rash; rash was a red pin prick appearance; couldn't move arm; tongue swelling; dizziness; tongue heavy; This case was reported by a consumer via call center representative and described the occurrence of feeling bad in a 54-year-old female patient who received Flu Seasonal QIV Dresden (Influenza vaccine Quadrivalent 2019-2020 season) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Shingrix (1st dose received in May 2019.) and MMR vaccine (received an MMR in June between her two doses of Shingrix.).   On 17th September 2019, the patient received Influenza vaccine Quadrivalent 2019-2020 season. On 18th September 2019, the patient received Shingrix. In September 2019, not applicable after receiving Influenza vaccine Quadrivalent 2019-2020 season and immediately after receiving Shingrix, the patient experienced feeling bad, urine discoloration, tiredness, pruritus, rash, red rash, mobility decreased, swollen tongue, dizziness and tongue abnormal feeling of. On 19th September 2019, the patient experienced chills and hives. The patient was treated with methylprednisolone and benadryl (nos) (Benadryl). On an unknown date, the outcome of the feeling bad, chills, urine discoloration, tiredness, hives, pruritus, rash, red rash, mobility decreased, swollen tongue and dizziness were unknown and the outcome of the tongue abnormal feeling of was recovered/resolved.   It was unknown if the reporter considered the chills, urine discoloration, tiredness, hives, pruritus, rash, red rash, mobility decreased, swollen tongue, dizziness and tongue abnormal feeling of to be related to Influenza vaccine Quadrivalent 2019-2020 season and Shingrix. It was unknown if the reporter considered the feeling bad to be related to Shingrix.  Additional case details were reported as follows: The patient had an unknown manufacturers flu vaccine in her left arm and on Wednesday the day before reporting she had her second dose of Shingrix in her right arm.  The patient stated she immediately felt bad after receiving the Shingrix vaccine.  On Thursday, before day of reporting, after 2 days of vaccination the patient covered in hives at the site and from head to toe.  She could not move her arm. She noted the rash was a red pin prick appearance on Friday, before day of reporting.  On Sunday, before day of reporting, the patient went to urgent care and was given methylprednisone prescription. She stated on the way leaving urgent care to get the prescription her tongue felt like it was swelling, she was dizzy and itching. Once she took a dose of the methylprednisone she noted the tongue issue resolved.  Thursday and Friday, before day of reporting she had chills, mono feeling which was how she described the tired feeling, and dark urine.  She was drinking water to resolve the dark urine, which was better. She stated the itching was better but notices it in her arm pits. Her tongue was no longer heave, the pin prick rash was the same and still all over her body, head to toe.  The patient was still tired but contributed that to taking round the clock Benadryl as prescribed from Urgent care. She was on a total of 5 days of methylprednisone. The reporter did note that, the patient received an MMR in June between her two doses of Shingrix. She denied a rash after the MMR. The emergency room visit was required. The reporter consented to follow up. This case has been linked with cases US2019172796 and US2019173375 reported by the same reporter.