Age: 64.0
Sex: F
Vaccine: COVID19
Symptoms: Cerebrovascular accident, Exostosis, Fall, Foot deformity, Frustration tolerance decreased
Clinical narrative: Stroke; not able to walk anymore/even to go bathroom; got spurs in back; teeth started breaking off; tried to get up out of bed and fell; So frustrated because, before, she could at least walk with cane/It is really frustrating; right leg drags; toes have become hammer toes; lost lot of weight, got to 78 pounds; can't use right arm to even comb hair; cramps up again; This is a spontaneous report received from a Consumer or other non HCP.  A 64-year-old female patient received BNT162b2 (BNT162B2), on 22Mar2021 as dose 2, single (Lot number: EN6190) at the age of 64 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "first stroke", start date: May2014 (unspecified if ongoing); "bad kidneys" (ongoing); "high cholesterol" (ongoing); "high blood pressure" (ongoing). The patient took concomitant medications. Vaccination history included: BNT162b2 (DOSE 1, SINGLE, Bach/Lot Number: EL9266, Anatomical location: shoulder upper arm, left), administration date: 01Mar2021, when the patient was 64-year-old, for COVID-19 immunisation. The following information was reported: GAIT INABILITY (disability, medically significant) with onset Mar2021, outcome "not recovered", described as "not able to walk anymore/even to go bathroom"; FRUSTRATION TOLERANCE DECREASED (disability) with onset 2021, outcome "unknown", described as "So frustrated because, before, she could at least walk with cane/It is really frustrating"; MOBILITY DECREASED (disability) with onset 2021, outcome "unknown", described as "can't use right arm to even comb hair"; MUSCLE SPASMS (disability) with onset 2021, outcome "unknown", described as "cramps up again"; EXOSTOSIS (disability, medically significant) with onset 2021, outcome "unknown", described as "got spurs in back"; WEIGHT DECREASED (disability) with onset 2021, outcome "unknown", described as "lost lot of weight, got to 78 pounds"; GAIT DISTURBANCE (disability) with onset 2021, outcome "unknown", described as "right leg drags"; TOOTH FRACTURE (disability, medically significant) with onset 2021, outcome "unknown", described as "teeth started breaking off"; FOOT DEFORMITY (disability) with onset 2021, outcome "unknown", described as "toes have become hammer toes"; FALL (disability) with onset 2021, outcome "unknown", described as "tried to get up out of bed and fell"; CEREBROVASCULAR ACCIDENT (hospitalization, disability, medically significant), outcome "unknown", described as "Stroke". The events "not able to walk anymore/even to go bathroom", "got spurs in back", "teeth started breaking off", "tried to get up out of bed and fell", "so frustrated because, before, she could at least walk with cane/it is really frustrating", "right leg drags", "toes have become hammer toes", "lost lot of weight, got to 78 pounds", "can't use right arm to even comb hair" and "cramps up again" required physician office visit. The event "stroke" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Kidney: (unspecified date) 18 %; (unspecified date) 33 %; Magnetic resonance imaging: (Sep2021) found spur in lower back; Weight: (unspecified date) almost 115; Weight: (2021) 78 lbs, notes: got down. Therapeutic measures were taken as a result of cerebrovascular accident, gait inability, exostosis, tooth fracture, fall, frustration tolerance decreased, gait disturbance, foot deformity, weight decreased, mobility decreased, muscle spasms. Clinical course: Received Second dose in shoulder, left upper arm. Patient was in hospital for Stroke on 28Mar2022 to Unspecified. Before getting shot, was able to walk with cane. Right after shot, was not able to walk anymore, had to use roller. caller got third shot but, was Moderna on 15Dec2021 and side effects occurred after second shot, caller not able to walk anymore. Caller states, she got shot, was fine. Came home, fell asleep like normal. When she woke up next morning, tried to get up out of bed and fell. From then, has not been able to walk, uses either roller or wheelchair, even to go bathroom. Doctor said after second shot, she got spurs in back, needed surgery. They could not guarantee, if she had surgery, it would help very much. Told her, it was 20 percent possibility she would come back to normal and be able to walk with cane. Did not let them operate, was scared. Has had 3 birthdays since then. Max weight right now would be almost 115. When she had her second stroke, was at (withheld). When she started seeing another doctor, started getting dental work. Somehow almost killed herself, got down to 78 pounds. Had taken her a couple years to get back to where she was right now. Stroke: Clarified, she had last stroke 28Mar2022. When second person heard in background, caller states, that was her sister, who was her caregiver, they live together. If there was any question not understood, her sister can speak but, caller wants to do this herself. Clarified, this stroke occurred after Covid vaccines she had in 2021. Clarified, this was caller's first time reporting this Pfizer but, doctor said she was going to report it because, she told caller not to take anymore shots. Somehow, got a Moderna shot or whatever, was going through different doctor. They did not listen to her. She still can't walk. Not able to walk anymore. So frustrated because, before, she could at least walk with cane. Now, can't even do that. Knows she was old, does not know how long she was going to live. Wants to be as independent as she can. About the same. Broke first rollator, almost a year later, had to get a second one. When she does use rollator, right leg drags, does not want to walk or move the way other one does. Clarified, caller referring to rollator, described by caller as, walker with wheels. Had even gone to physical therapy. Treatment was Had gel that she puts on foot because, toes had become hammer toes. Had this cream she puts on there, relieves it a bit. When she tries to get out of bed, to get wheelchair or rollator, cramps up again. It was really frustrating. They keep her on blood pressure medicine, high cholesterol medicine because, she had bad kidneys,  cant take a lot of pills. Kidneys went from 18 percent to 33 percent, since she had first stroke. Clarified, she had first stroke in 2014, wants to say, around May2014. Clarified, first stroke occurred prior to receiving Covid vaccines in 2021. Thinks she was still having lasting effects because, can't use right arm to even comb hair. Right leg does not work right. Like, half of her body does not work right. Took vaccine because everybody said they needed to get it, especially, if old. Went and took it because, doctors said they needed to make sure they were protected, so they would not get Covid. Took shot but, after it, can't walk anymore, doctor said, no more shots. But, she got Moderna Dec2021. Was taking high blood pressure and high cholesterol medicine but, nothing related to the corona virus shot. Had MRI done, found spur in lower back, wanted to operate but, could not. They only said, she had 25 percent chance, or getting better, to where she could walk. They were not sure if she would come out of it because of stupid fact that she had strokes and because of her kidneys. They don't want her to extreme medication if she does not have to. Wants to say, it was about 6 months after second corona virus shot, she has this MRI. Kidney doctor is also at same hospital. Patient did not received any prior vaccinations within 4 weeks. No family medical history relevant to adverse events. Adverse Events: stroke, AE required Emergency Room; Had to got to go emergency room, was put in ICU for about week. This was after she started splitting teeth, lost lot of weight, got to 78 pounds. Was scared she would had another stroke because, she lost so much weight. Clarified, after she got second corona virus shot, her teeth started breaking off. Got to point that, she had trouble finding dentist that  would pull rest of the pieces of teeth out becuase, fact that, because of her kidneys they can't give her anesthesia because, they are not sure she will make it out of it. Caller states, it was a mess. Was going to doctor, at least once a month. When clarifying ICU and hospital stay, caller states, she had that other stroke in 28Mar2022. Was put in hospital, after out of hospital, they put her in rehab. That did not work, signed herself out, went home.  Clarified, since stroke 28Mar2022, was hospitalized almost 2weeks. From there, went to rehab, that did not work, went home. When she first had first stroke in 2014, was at (withheld), they would get her up in morning, help take shower, would go Physical Therapy. Then, would go back to room, to eat, take break. They would come back in couple hours to bring dinner, then go walk again. Nurses were nice but, she would get mad because, they would want her to go exercise, and she wanted to stay in bed and be lazy. Doctor told her, there were no days off, she would had to try to exercise every day. But her foot does not want to work right, does not help when she had to do chair exercises, stand up and sit down. Can't do that because, her foot gets super, like, hammer toes, hurts for her to stand. Clarified, caller was referring to first stroke in 2014. if admitted to ICU, duration of stay: Clarified, she was hospital for total of 2 weeks, 1 of those weeks, was in ICU. Mini stroke: After she got out of rehab, not sure, thinks she had mini stroke because, her face did not want to work. Does not talk right. Doctor told her she needed to see eye specialist because, her eyes don't water but, wakes up with crust in one of her eyes. Think it was about 2 months after she had stroke in Mar2022, was maybe Jun or Jul2022. When she went to (Withheld) and rehab because, she changed doctors, they did not know what kind of medicine to put her on, did not give her medicine. Thinks that was why she had mini stroke because, if they knew she needed medicine, why did they not give it to her. Made her mad but, what can she do. Autopsy Information was N/A.