chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 6.0
Sex: F
Vaccine: FLU3
Symptoms: Urticaria
Clinical narrative: Widespread small hives ~2.5 hours after vaccine administration
Age: 54.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Axillary pain, Breast pain, Cellulitis, Injection site pain, Injection site rash
Clinical narrative: Fever up to 101 2 days after injection of Pneumovax and inactivated Fluvirin L deltoid. Within 5 days a blistering rash started at the injection site and around her left breast..a cellulitis type reaction. She had pain under her breast and in her left axilla and at the injection site that lasted more than 2 weeks...all sx eventually resolved.
Age: 54.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Injection site vesicles, Pyrexia
Clinical narrative: Fever up to 101 2 days after injection of Pneumovax and inactivated Fluvirin L deltoid. Within 5 days a blistering rash started at the injection site and around her left breast..a cellulitis type reaction. She had pain under her breast and in her left axilla and at the injection site that lasted more than 2 weeks...all sx eventually resolved.
Age: 21.0
Sex: F
Vaccine: FLU3
Symptoms: Complex partial seizures, Computerised tomogram normal, Electroencephalogram normal, Grand mal convulsion, Nuclear magnetic resonance imaging normal
Clinical narrative: On 11/5/07 at approximately 11am I had a Grand Mal seizure for the first time in my life with no prior symptoms or signalment. I was taken to the emergency room at the University of Missouri Hospital. In the emergency room at 2:15pm I had another seizure, a complex partial with secondary generalization seizure. I had a MRI, CAT scan and EEG, all of which were negative. I was treated with Dilantin 100mg 3 times per day, but have been switched to carbamazepine (Tegretol) 300mg orally per day for at least 6 months. I had to stay in the hospital three additional days due to thrombophlepitis of my upper left arm where a cathether had been placed. I was treated with Ibuprofen and Bactrim DS tablet orally for the thrombophlepitis. 12/26/07-records received for DOS 11/10-11/11/07-DC DX: Seizure.Seen in ED on 11/5 and 11/6 for new onset of sezure. After visit to ED and subsequent DC she was found near the pharmacy hypersomnolent. In ED on 11/5/07 observed generalized tonic-clonic seizure. Developed pruritis, rash, left orbital swelling presumably from Vancomycin.  02/03/2010 Petite Mal Seizure 12/21/07.
Age: 21.0
Sex: F
Vaccine: FLU3
Symptoms: Thrombophlebitis
Clinical narrative: On 11/5/07 at approximately 11am I had a Grand Mal seizure for the first time in my life with no prior symptoms or signalment. I was taken to the emergency room at the University of Missouri Hospital. In the emergency room at 2:15pm I had another seizure, a complex partial with secondary generalization seizure. I had a MRI, CAT scan and EEG, all of which were negative. I was treated with Dilantin 100mg 3 times per day, but have been switched to carbamazepine (Tegretol) 300mg orally per day for at least 6 months. I had to stay in the hospital three additional days due to thrombophlepitis of my upper left arm where a cathether had been placed. I was treated with Ibuprofen and Bactrim DS tablet orally for the thrombophlepitis. 12/26/07-records received for DOS 11/10-11/11/07-DC DX: Seizure.Seen in ED on 11/5 and 11/6 for new onset of sezure. After visit to ED and subsequent DC she was found near the pharmacy hypersomnolent. In ED on 11/5/07 observed generalized tonic-clonic seizure. Developed pruritis, rash, left orbital swelling presumably from Vancomycin.  02/03/2010 Petite Mal Seizure 12/21/07.
Age: 0.33
Sex: M
Vaccine: DTAPHEPBIP, HIBV, PNC, RV5
Symptoms: Facial palsy, Oral mucosal blistering
Clinical narrative: After receiving vaccines on 12/19/2007, baby developed palsy of Lt. face with drooping Lt. eyelid and drooping Lt. side of mouth.            12/22/07 trial of oral predinison and oral acyclovir given. Noted small blisters in mouth at the time of visit.
Age: 48.0
Sex: F
Vaccine: RAB
Symptoms: Bedridden, Burning sensation, Fatigue, Mental impairment, Muscle spasms
Clinical narrative: On August 19, 2007, patient sarted the Rabies Vaccine series.  She received Rabies Immune Globuline (Human), HyperRAB S/D and the first injection of IMOVAX Rabies Vaccine.  During the course of the 28 days when receiving the additional vaccine injections, She became increasingly fatigued and revved up (restless).  Her mental processing decreased, for example a simple math problem became to much to do.  Her arms and legs started to tingle and burn, she had muscle cramping also. As the week progressed, she felt like she was getting a bad flu.  She could not accomplish normal chors and activities.  By about one week (day 35 from the beginning of the rabies vaccine series) after the last vaccine injection she could barely get out of bed. She was bedridden for about 6 weeks. She is currently seeking medical advice.  She had a CT scan of her brain,the results normal. She has had extensive blood work, all normal.                                                                     Can you help with which course of action to take.
Age: 48.0
Sex: F
Vaccine: RAB
Symptoms: Paraesthesia, Restlessness
Clinical narrative: On August 19, 2007, patient sarted the Rabies Vaccine series.  She received Rabies Immune Globuline (Human), HyperRAB S/D and the first injection of IMOVAX Rabies Vaccine.  During the course of the 28 days when receiving the additional vaccine injections, She became increasingly fatigued and revved up (restless).  Her mental processing decreased, for example a simple math problem became to much to do.  Her arms and legs started to tingle and burn, she had muscle cramping also. As the week progressed, she felt like she was getting a bad flu.  She could not accomplish normal chors and activities.  By about one week (day 35 from the beginning of the rabies vaccine series) after the last vaccine injection she could barely get out of bed. She was bedridden for about 6 weeks. She is currently seeking medical advice.  She had a CT scan of her brain,the results normal. She has had extensive blood work, all normal.                                                                     Can you help with which course of action to take.
Age: 15.0
Sex: F
Vaccine: FLUN3, HPV4
Symptoms: Oedema peripheral
Clinical narrative: Entire left arm swelled 2 days after recieving 3rd Gardasil injection. Recieved ibprofen and ice.
Age: 61.0
Sex: F
Vaccine: DTAP
Symptoms: Pyrexia
Clinical narrative: I was given a Tdap booster on 12/20/07 sometime after 12 noon. I developed soar arm, fever and a heavy feeling in head. All day on 21st I was unwell feeling total lack of energy.  So, I stayed home and rested.  On 22nd the feeling continued; so after staying in bed till past noon time, I finally got up and went to the kitchen to make my usual first meal: tea, toast topped with cheese and avocado slices.  I felt really dizzy standing at the kitchen counter, so sat down at the nearest chair.  The dizziness continued and now my vision got blurred.  I was scared since it has never happened to me.  I somehow got up went to the nearest bathroom to pass urine, I was still dizzy, so I sat there for a while thinking who I should telephone, a neighbor or a friend?  I felt may be I should eat first to take care of the dizzy spell, so  slowly, placing a hand on adjacent walls, I came back to the chair and tried to eat my toast and sip my tea.  The blurry vision continued; I waited.  After quite a few minutes it slowly started going away.  I continued sitting, and ate my toast and drank my tea.  Then I took my cordless phone, and lay down on my bed; I was feeling quite cold(my apartment heating was on) as if I was coming down with high fever; so I covered myself with blankets, sheets and decided to rest for a while.  My phone rang, a friend was calling to invite me for lunch the next day.  I declined describing my situation to her.  She was worried and asked if she should come over(she lives 30 miles away, has a small kid who has been sick); I told her not to.  She said then she would check back with me in a few hrs.  I slept then got up around 6:30 pm; called another friend and said I can't come for dinner at her place(she lives only 5 miles away) and described how I felt.  At 7pm, I forced myself to get up and have dinner; then sat in a reclining comfortable chair and watched TV. I do my daily walk in the evenings, no matter what; try not to miss it.  But decided not to go out. Both my friends called to see how I was, and if it was ok for me to spend the night alone(I live alone).  I did not want to interrupt my friends plans just prior to x'mas, so I told them I would be ok.  I was feeling very feverish again by 11pm, so got up and went to bed. Today I woke up around 9am, but was still tired, so I got up around 11 am and had a late breakfast.  My friend went online to do research and telephoned to tell me that this could be a severe reaction to the immunization shot.  Now I am a bit better; so I went thru' the paperwork handed to me by the nurse who administered the injection and told me to take tylenol(I did take Tylenol) since I may experience soar arm, fever.  But I was not told about the dizzy spell, blurry vision. I tried to call the 800 number of Vaers hoping to talk to someone...NO LUCK!  So, here I am, not fully recovered trying to fill out the form hoping it would help someone in future.  My time is precious, since I have a lot of preparatory work that I must do before I leave for my extended trip to India in a few days.
Age: 47.0
Sex: F
Vaccine: FLUX, TTOX
Symptoms: Arthralgia, Arthritis, Joint stiffness, Pain, Pain in extremity
Clinical narrative: On December 3rd, my family physician, during a routine visit to receive the flu vaccine told me I needed a tetnus booster to which I agreed.  Approximately one and one half weeks later I woke up in the morning with every single solitary joint in my body stiff and aching right down to the joints in my toes.   I contacted Dr. and was told that those symptoms were not typical of the tetanus shot.  I disagree with his findings.  This arthritis and pain and stiffness of all of my joints began on or about December 14th and still persisits.  I am awakened many times during the night due to it.  It is difficult for me to get up after sitting down or driving for 15 mintues or so.  Now, two nights ago on December 21 I experience very deep aching pain in my right leg all night.  I am also experiencing sharp pains often in various parts of my body.
Age: 47.0
Sex: F
Vaccine: FLUX, TTOX
Symptoms: Sleep disorder
Clinical narrative: On December 3rd, my family physician, during a routine visit to receive the flu vaccine told me I needed a tetnus booster to which I agreed.  Approximately one and one half weeks later I woke up in the morning with every single solitary joint in my body stiff and aching right down to the joints in my toes.   I contacted Dr. and was told that those symptoms were not typical of the tetanus shot.  I disagree with his findings.  This arthritis and pain and stiffness of all of my joints began on or about December 14th and still persisits.  I am awakened many times during the night due to it.  It is difficult for me to get up after sitting down or driving for 15 mintues or so.  Now, two nights ago on December 21 I experience very deep aching pain in my right leg all night.  I am also experiencing sharp pains often in various parts of my body.
Age: 65.0
Sex: F
Vaccine: VARZOS
Symptoms: Herpes zoster
Clinical narrative: Information has been received from a physician concerning an over 65 year old female who in January 2007, received 0.65 ml dose of Zostavax (Oka/Merck). On 31-OCT-2007, she developed shingles. Unspecified medical treatment was sought. At the time of this report, it was reported that she has not recovered. A product quality complaint was not reported. Additional information was not available. Additional information has been requested.
Age: 1.75
Sex: F
Vaccine: DTAPHEPBIP, HIBV, MMR
Symptoms: Cough, Injection site erythema, Pyrexia, Rash, Rash morbilliform
Clinical narrative: 1 day after vaccine administration, the patient developed fever, runny nose, and cough. Also had very red injection sites. 1 1/2 week later, she developed rash, which was diagnosed as measles rash.
Age: 1.75
Sex: F
Vaccine: DTAPHEPBIP, HIBV, MMR
Symptoms: Rhinorrhoea
Clinical narrative: 1 day after vaccine administration, the patient developed fever, runny nose, and cough. Also had very red injection sites. 1 1/2 week later, she developed rash, which was diagnosed as measles rash.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site rash, Injection site warmth
Clinical narrative: 8 x 7 cm warm, slightly tender red rash at injection site on left deltoid
Age: 62.0
Sex: F
Vaccine: PPV
Symptoms: Arthralgia, Chills, Fatigue, Headache, Injection site erythema
Clinical narrative: Symptoms began about 15 hours after injection. Nausea and vomiting. Chills and fever of 102.6 for 24 hours following vaccine, swelling, redness, pain at site--swelling and redness was 6 inches in diameter.  Moderate pain in joints lasting 48 hours after injection. Moderate neck, headache and shoulder pain lasting several days. Site of injection still has lump (1.5 inches in diameter)and soreness 19 days after injection.  Neck and shoulder pain are still bothersome.  Extreme fatigue for several days after injection.  I am still not back to my normal self.  Fatigue is still a problem.
Age: 62.0
Sex: F
Vaccine: PPV
Symptoms: Injection site mass, Injection site pain, Injection site swelling, Musculoskeletal pain, Nausea
Clinical narrative: Symptoms began about 15 hours after injection. Nausea and vomiting. Chills and fever of 102.6 for 24 hours following vaccine, swelling, redness, pain at site--swelling and redness was 6 inches in diameter.  Moderate pain in joints lasting 48 hours after injection. Moderate neck, headache and shoulder pain lasting several days. Site of injection still has lump (1.5 inches in diameter)and soreness 19 days after injection.  Neck and shoulder pain are still bothersome.  Extreme fatigue for several days after injection.  I am still not back to my normal self.  Fatigue is still a problem.
Age: 62.0
Sex: F
Vaccine: PPV
Symptoms: Neck pain, Pyrexia, Vomiting
Clinical narrative: Symptoms began about 15 hours after injection. Nausea and vomiting. Chills and fever of 102.6 for 24 hours following vaccine, swelling, redness, pain at site--swelling and redness was 6 inches in diameter.  Moderate pain in joints lasting 48 hours after injection. Moderate neck, headache and shoulder pain lasting several days. Site of injection still has lump (1.5 inches in diameter)and soreness 19 days after injection.  Neck and shoulder pain are still bothersome.  Extreme fatigue for several days after injection.  I am still not back to my normal self.  Fatigue is still a problem.
Age: 21.0
Sex: M
Vaccine: FLU3, HEP, HEPA, FLU3, HEP, HEPA
Symptoms: Urticaria
Clinical narrative: patient developed itching on palms about 12 hours after vaccines-day following vaccination patient developed hives-no other systemic symptoms.  patient had hives off/on for 3 months-none over the last 2 months.
Age: 21.0
Sex: M
Vaccine: FLU3, HEP, HEPA, FLU3, HEP, HEPA
Symptoms: Pruritus, Urticaria
Clinical narrative: patient developed itching on palms about 12 hours after vaccines-day following vaccination patient developed hives-no other systemic symptoms.  patient had hives off/on for 3 months-none over the last 2 months.
Age: 47.0
Sex: F
Vaccine: TDAP, TYP, YF, TDAP, TYP, YF, TDAP, TYP, YF
Symptoms: Gait disturbance, Guillain-Barre syndrome, Paraesthesia, Paraesthesia oral
Clinical narrative: Initial report received on 07 September 2007 from the Centers for Disease Control and Prevention dated 10 September 2007, VAERS# 288086. A 47-year-old female patient had received an injection of YF-Vax, lot number not reported; an injection of Adacel, lot number not reported; and an injection of Typhim VI, lot number not reported; on 04 June 2007. Routes and sites of administration were not reported. Sixteen days post vaccination, the patient experienced difficulty walking, and tingling in the hands, feet, and tongue. She was subsequently hospitalized for 60 days with the diagnosis of Guillain Barre Syndrome. The patient was being followed by the Clinical Immunization Safety Network (CISA). Recovery status was not reported.
Age: 27.0
Sex: F
Vaccine: TDAP, TDAP
Symptoms: Erythema, Hypoaesthesia, Paraesthesia
Clinical narrative: Initial report received from a health care provider on 25 September 2007.  A 27-year-old female patient had received an intramuscular left arm injection of Adacel, lot number C2730RA on 18 June 2007 and two days later experienced numbness and tingling in her left arm and 50mm x 50mm (+) erythema in the left mid-tricep region.  The patient received corrective treatment with Ibuprofen.  The duration for the event was not reported.  The patient had no past medical history and had not been ill or receiving any concomitant medications at the time of vaccination.  Prior date(s) for receipt of Tetanus booster doses and the patient's vaccination history were not provided.  No additional information was received and the patient was listed as recovered at the time of the report.  Follow-up information received on 24 October 2007 from a health care professional.  The numbness and tingling had radiated to the left middle, 4th and 5th fingers.  The patient also experienced a 50mm x 50mm induration to the left mid tricep area, and left arm myalgia which resolved on 25 June 2007.  Treatment had included ibuprofen and cool compresses.  The patient's vaccination history was unknown.  The case was reviewed by the reporter, and there was no additional information at this time.  This reporter for this event is the same as for case numbers: 200703236, 200703237 and 200702814 which concern large areas of redness, swelling and pain.  These cases have also been submitted to VAERS by the initial reporter.
Age: 27.0
Sex: F
Vaccine: TDAP, TDAP
Symptoms: Erythema, Hypoaesthesia, Induration, Myalgia, Paraesthesia
Clinical narrative: Initial report received from a health care provider on 25 September 2007.  A 27-year-old female patient had received an intramuscular left arm injection of Adacel, lot number C2730RA on 18 June 2007 and two days later experienced numbness and tingling in her left arm and 50mm x 50mm (+) erythema in the left mid-tricep region.  The patient received corrective treatment with Ibuprofen.  The duration for the event was not reported.  The patient had no past medical history and had not been ill or receiving any concomitant medications at the time of vaccination.  Prior date(s) for receipt of Tetanus booster doses and the patient's vaccination history were not provided.  No additional information was received and the patient was listed as recovered at the time of the report.  Follow-up information received on 24 October 2007 from a health care professional.  The numbness and tingling had radiated to the left middle, 4th and 5th fingers.  The patient also experienced a 50mm x 50mm induration to the left mid tricep area, and left arm myalgia which resolved on 25 June 2007.  Treatment had included ibuprofen and cool compresses.  The patient's vaccination history was unknown.  The case was reviewed by the reporter, and there was no additional information at this time.  This reporter for this event is the same as for case numbers: 200703236, 200703237 and 200702814 which concern large areas of redness, swelling and pain.  These cases have also been submitted to VAERS by the initial reporter.
Age: 61.0
Sex: F
Vaccine: TDAP, TDAP
Symptoms: Discomfort, Erythema, Induration, Oedema, Skin warm
Clinical narrative: Initial report received from a health care provider on 25 September 2007.  A 62-year-old female patient had received an intramuscular left deltoid injection of Adacel, lot number C2730AA on 13 June 2007 and 24 hours later experienced a three inch by three inch area of erythema and edema on her left arm, hard to touch, warm and uncomfortable.  The patient received corrective treatment with Augmentin.  The duration of the event was not reported.  The patient had no past medical history and had not been ill or receiving any concomitant medications at the time of vaccination.  Prior date(s) for receipt of tetanus booster doses and the patient's vaccination history were not provided.  No additional information was received and the patient was listed as recovered at the time of the report. Follow-up information received on 24 October 2007.  The patient experienced additional symptoms of itching at the injection site on the day of the vaccination (13 June 2007) that ended on 20 June 2007.  The final diagnosis the these adverse events was left arm cellulitis (limited to upper arm).  The event of injection site reaction was removed since the final diagnosis was made of cellulitis.  The patient recovered and did not follow-up with the physician; and no further information is expected.  This reporter for this event is the same as for case numbers: 2007-03235, 2007-03237 and 2207-02814 which concern large areas of redness, swelling and pain.  These cases have also been submitted to VAERS by the initial reporter.
Age: 61.0
Sex: F
Vaccine: TDAP, TDAP
Symptoms: Injection site cellulitis, Injection site discomfort, Injection site erythema, Injection site induration, Injection site oedema
Clinical narrative: Initial report received from a health care provider on 25 September 2007.  A 62-year-old female patient had received an intramuscular left deltoid injection of Adacel, lot number C2730AA on 13 June 2007 and 24 hours later experienced a three inch by three inch area of erythema and edema on her left arm, hard to touch, warm and uncomfortable.  The patient received corrective treatment with Augmentin.  The duration of the event was not reported.  The patient had no past medical history and had not been ill or receiving any concomitant medications at the time of vaccination.  Prior date(s) for receipt of tetanus booster doses and the patient's vaccination history were not provided.  No additional information was received and the patient was listed as recovered at the time of the report. Follow-up information received on 24 October 2007.  The patient experienced additional symptoms of itching at the injection site on the day of the vaccination (13 June 2007) that ended on 20 June 2007.  The final diagnosis the these adverse events was left arm cellulitis (limited to upper arm).  The event of injection site reaction was removed since the final diagnosis was made of cellulitis.  The patient recovered and did not follow-up with the physician; and no further information is expected.  This reporter for this event is the same as for case numbers: 2007-03235, 2007-03237 and 2207-02814 which concern large areas of redness, swelling and pain.  These cases have also been submitted to VAERS by the initial reporter.
Age: 61.0
Sex: F
Vaccine: TDAP, TDAP
Symptoms: Injection site pruritus, Injection site warmth
Clinical narrative: Initial report received from a health care provider on 25 September 2007.  A 62-year-old female patient had received an intramuscular left deltoid injection of Adacel, lot number C2730AA on 13 June 2007 and 24 hours later experienced a three inch by three inch area of erythema and edema on her left arm, hard to touch, warm and uncomfortable.  The patient received corrective treatment with Augmentin.  The duration of the event was not reported.  The patient had no past medical history and had not been ill or receiving any concomitant medications at the time of vaccination.  Prior date(s) for receipt of tetanus booster doses and the patient's vaccination history were not provided.  No additional information was received and the patient was listed as recovered at the time of the report. Follow-up information received on 24 October 2007.  The patient experienced additional symptoms of itching at the injection site on the day of the vaccination (13 June 2007) that ended on 20 June 2007.  The final diagnosis the these adverse events was left arm cellulitis (limited to upper arm).  The event of injection site reaction was removed since the final diagnosis was made of cellulitis.  The patient recovered and did not follow-up with the physician; and no further information is expected.  This reporter for this event is the same as for case numbers: 2007-03235, 2007-03237 and 2207-02814 which concern large areas of redness, swelling and pain.  These cases have also been submitted to VAERS by the initial reporter.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Asthenia, Dysphagia, Dyspnoea, Hypoaesthesia, Intestinal functional disorder
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Regurgitation, Speech disorder, Vision blurred
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Guillain-Barre syndrome, Muscular weakness, Neuropathy peripheral
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Asthenia, Dysphagia, Dyspnoea, Gait disturbance, Guillain-Barre syndrome
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Hypoaesthesia, Intestinal functional disorder, Regurgitation, Speech disorder, Swelling
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Vision blurred
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 17.0
Sex: M
Vaccine: HEPAB, MNQ, TDAP, HEPAB, MNQ, TDAP, UNK, HEPAB, MNQ, TD, HEPAB, MNQ, TDAP
Symptoms: Hypoaesthesia, Intestinal functional disorder, Regurgitation, Speech disorder, Vision blurred
Clinical narrative: Initial information received on 16 September 2007 from the Centers for Disease Control and Prevention, VAERS# 290355. The initial reporter to the CDC had been a health care professional. A 17-year-old male received an intramuscular injection of Menactra (Lot number U2394BA, site of vaccination unknown), an intramuscular injection of Adacel (lot number C2769AA, site of vaccination unknown) and an intramuscular injection of Twinrix (Lot number AHABB100AA, site of administration unknown) on 22 August 2007. On 11 September 2007, 20 days after receiving the vaccines, the patient was diagnosed with possible Guillain barre Syndrome. The patient complained of numbness to extremities, difficulty speaking, shortness of breath, trouble swallowing, blurred vision, difficulty walking, weakness throughout the body, bowel problems, regurgitation and difficulty taking deep breaths. The event required hospitalization. Recovery status was not reported. No additional information was provided at the time of this report.
Age: 14.0
Sex: M
Vaccine: MNQ, TDAP, MNQ, TDAP, MNQ, TDAP
Symptoms: Muscle twitching
Clinical narrative: Initial report received from a health care provider on 18 September 2007.  A 14-year-old male patient with a history of asthma, had received an intramuscular left deltoid injection of Adacel, lot number C2572AA and an intramuscular right deltoid injection of Menactra, lot number U2406AA on 17 September 2007 and 19 hours later experienced "twitching of upper left arm with pain in entire left arm".  The patient had no illness at the time of vaccination.  It was not reported if the patient had been evaluated by a physician or if they had received any corrective treatment.  No additional information was provided and the patient had not recovered from the event at the time of the report.
Age: 14.0
Sex: M
Vaccine: MNQ, TDAP, MNQ, TDAP, MNQ, TDAP
Symptoms: Muscle twitching, Pain in extremity
Clinical narrative: Initial report received from a health care provider on 18 September 2007.  A 14-year-old male patient with a history of asthma, had received an intramuscular left deltoid injection of Adacel, lot number C2572AA and an intramuscular right deltoid injection of Menactra, lot number U2406AA on 17 September 2007 and 19 hours later experienced "twitching of upper left arm with pain in entire left arm".  The patient had no illness at the time of vaccination.  It was not reported if the patient had been evaluated by a physician or if they had received any corrective treatment.  No additional information was provided and the patient had not recovered from the event at the time of the report.
Age: 1.0
Sex: M
Vaccine: UNK, HIBV, MMR, PNC, VARCEL
Symptoms: Diarrhoea, Vomiting
Clinical narrative: Vom., diar., Bratdiet, fluid Flu if doesn't improve
Age: 0.6
Sex: M
Vaccine: DTAPHEPBIP, FLU3, HIBV, PNC, DTAPHEPBIP, FLU3, HIBV, PNC
Symptoms: Blood culture negative, Convulsion, Full blood count normal, Lumbar puncture, Pyrexia
Clinical narrative: GENERALIZED SEIZURE with Temp 102 at 11:45 PM (10/18/07) -> ER
Age: 0.6
Sex: M
Vaccine: DTAPHEPBIP, FLU3, HIBV, PNC, DTAPHEPBIP, FLU3, HIBV, PNC
Symptoms: Urine analysis normal
Clinical narrative: GENERALIZED SEIZURE with Temp 102 at 11:45 PM (10/18/07) -> ER
Age: 0.6
Sex: M
Vaccine: DTAPHEPBIP, FLU3, HIBV, PNC, DTAPHEPBIP, FLU3, HIBV, PNC
Symptoms: Body temperature increased, Convulsion
Clinical narrative: GENERALIZED SEIZURE with Temp 102 at 11:45 PM (10/18/07) -> ER
Age: 23.0
Sex: F
Vaccine: FLUN3, HEPAB, YF, FLUN3, HEPAB, YF
Symptoms: Dyspnoea, Throat tightness, Urticaria
Clinical narrative: 23 yo healthy pt with acute onset of coughing, dyspnea, glossal/pharyngeal edema, pruritis and hives 20 minutes after receiving 4 immunizations at immunization clinic (Yellow Fever, Influenza,  Hepatitis A and B).  Pt was sent to healthcare facility where she was treated with Oxygen, Benadryl 50mg x 2, Solumedrol 125mg x2, Albuterol neb, and epinephrine 0.3mg subcut, 2L NS.  Pt states she began to feel better after treatment and had no recurrence of symptoms.  After pt was stabilized she was transferred to hospital for observation and was than transferred for continued observation for refractory symptoms.  12/27/2007 MR received for ER visit 12/7-8/2007 with D/C DX: Anaphylactic Reaction to Immunization.  Pt developed acute onset of coughing, dyspnea, glossal/pharyngeal edema, hives and pruritis w/in 20 minutes of 4 vax. Pt txd with Epi, Benadryl, Solumedrol and albuterol.  Developed more hives. Observed o/n with no refractory sx.
Age: 23.0
Sex: F
Vaccine: FLUN3, HEPAB, YF, FLUN3, HEPAB, YF
Symptoms: Cough, Dyspnoea, Pharyngeal oedema, Pruritus, Urticaria
Clinical narrative: 23 yo healthy pt with acute onset of coughing, dyspnea, glossal/pharyngeal edema, pruritis and hives 20 minutes after receiving 4 immunizations at immunization clinic (Yellow Fever, Influenza,  Hepatitis A and B).  Pt was sent to healthcare facility where she was treated with Oxygen, Benadryl 50mg x 2, Solumedrol 125mg x2, Albuterol neb, and epinephrine 0.3mg subcut, 2L NS.  Pt states she began to feel better after treatment and had no recurrence of symptoms.  After pt was stabilized she was transferred to hospital for observation and was than transferred for continued observation for refractory symptoms.  12/27/2007 MR received for ER visit 12/7-8/2007 with D/C DX: Anaphylactic Reaction to Immunization.  Pt developed acute onset of coughing, dyspnea, glossal/pharyngeal edema, hives and pruritis w/in 20 minutes of 4 vax. Pt txd with Epi, Benadryl, Solumedrol and albuterol.  Developed more hives. Observed o/n with no refractory sx.
Age: 4.0
Sex: M
Vaccine: FLU3, PPV, FLU3, PPV
Symptoms: Abasia, Body temperature increased, Injection site infection, Pyrexia, Surgery
Clinical narrative: Injection given 12/5/07.  Fever started that night into next day-104 degrees F.  Couldn't walk, knee swollen, thigh red & tender.  Went to local ER; then transported by ambulance to hospital.  They ultrasounded knee - emergency surgery to drain fluids around incision site.  Second surgery done 12/9/07 to irrigate & drain fluid buildup at incision site.  Was released Monday Dec 10th at 4pm from hospital. Per 60 day follow up: This event was very traumatic on my child. He has a huge scare on his leg and he still has dreams about it. He is scared to go to the doctor's and still gets pain in the the leg.
Age: 4.0
Sex: M
Vaccine: FLU3, PPV, FLU3, PPV
Symptoms: Abasia, Incisional drainage, Injection site erythema, Injection site pain, Joint swelling
Clinical narrative: Injection given 12/5/07.  Fever started that night into next day-104 degrees F.  Couldn't walk, knee swollen, thigh red & tender.  Went to local ER; then transported by ambulance to hospital.  They ultrasounded knee - emergency surgery to drain fluids around incision site.  Second surgery done 12/9/07 to irrigate & drain fluid buildup at incision site.  Was released Monday Dec 10th at 4pm from hospital. Per 60 day follow up: This event was very traumatic on my child. He has a huge scare on his leg and he still has dreams about it. He is scared to go to the doctor's and still gets pain in the the leg.
Age: 4.0
Sex: M
Vaccine: FLU3, PPV, FLU3, PPV
Symptoms: Pyrexia, Surgery, Ultrasound scan
Clinical narrative: Injection given 12/5/07.  Fever started that night into next day-104 degrees F.  Couldn't walk, knee swollen, thigh red & tender.  Went to local ER; then transported by ambulance to hospital.  They ultrasounded knee - emergency surgery to drain fluids around incision site.  Second surgery done 12/9/07 to irrigate & drain fluid buildup at incision site.  Was released Monday Dec 10th at 4pm from hospital. Per 60 day follow up: This event was very traumatic on my child. He has a huge scare on his leg and he still has dreams about it. He is scared to go to the doctor's and still gets pain in the the leg.
Age: 55.0
Sex: F
Vaccine: TTOX
Symptoms: Arthralgia, Arthropathy, Fatigue, Injected limb mobility decreased, Musculoskeletal pain
Clinical narrative: Seriousness criteria: other - medically significant.  Initial report received from a patient on 03 August 2007.  A 55 year old female patient (with a medical history of no known allergies) was not able to "pick up anything with her right arm without severe pain", approximately 2 weeks (approximately on 23 June 2006) after she received tetanus toxoid (lot number U1683AB) intramuscularly in the right arm on 09 June 2006.  She was evaluated and an MRI showed "tears in her right shoulder and elbow".  She had occasional steroid injections in this arm which improved her symptoms for approximately 3 days.  She had been taking 7.5mg po Prednisone daily.  Her arm had improved.  She additionally reported occasional breakthrough low grade fevers of 100F, swelling of the hands and fatigue.  These symptoms continued to persist.  She had seen over 11 physicians but had not been specifically diagnosed, although rheumatoid arthritis was being considered.  No other vaccine was given at the same time.  No illnesses at vaccination time.  At the time of the report, she had not recovered.  Follow-up information received on 11 December 2007 from a health care professional.  The patient had no illnesses at the time of vaccination on 09 June 2006.  14 days post-vaccination, on 23 June 2007, she developed the previously reported symptoms.  It was not reported whether the patient was diagnosed with rheumatoid arthritis.  At the time of this report she had not recovered from her symptoms.
Age: 55.0
Sex: F
Vaccine: TTOX
Symptoms: Nuclear magnetic resonance imaging abnormal, Oedema peripheral, Pain, Pyrexia
Clinical narrative: Seriousness criteria: other - medically significant.  Initial report received from a patient on 03 August 2007.  A 55 year old female patient (with a medical history of no known allergies) was not able to "pick up anything with her right arm without severe pain", approximately 2 weeks (approximately on 23 June 2006) after she received tetanus toxoid (lot number U1683AB) intramuscularly in the right arm on 09 June 2006.  She was evaluated and an MRI showed "tears in her right shoulder and elbow".  She had occasional steroid injections in this arm which improved her symptoms for approximately 3 days.  She had been taking 7.5mg po Prednisone daily.  Her arm had improved.  She additionally reported occasional breakthrough low grade fevers of 100F, swelling of the hands and fatigue.  These symptoms continued to persist.  She had seen over 11 physicians but had not been specifically diagnosed, although rheumatoid arthritis was being considered.  No other vaccine was given at the same time.  No illnesses at vaccination time.  At the time of the report, she had not recovered.  Follow-up information received on 11 December 2007 from a health care professional.  The patient had no illnesses at the time of vaccination on 09 June 2006.  14 days post-vaccination, on 23 June 2007, she developed the previously reported symptoms.  It was not reported whether the patient was diagnosed with rheumatoid arthritis.  At the time of this report she had not recovered from her symptoms.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Abortion spontaneous, Drug exposure during pregnancy, Foetal heart rate abnormal, Nasopharyngitis, Ultrasound scan abnormal
Clinical narrative: Seriousness criteria: other - medically significant.  This case was reported by a health professional on 05 October 2007.  A 37-year-old female patient, with an allergy to penicillin, received an intramuscular injection of Adacel on 10 September 2007.  The patient, who was also a physician, had received a tetanus vaccine (manufacturer and lot number unknown) in January 2007.  She was pregnant at the time of vaccination, and the date of her last menstrual period was 23 August 2007.  Obstetric history included two previous pregnancies with normal, full-term deliveries.  An ultrasound on 02 October 2007 confirmed the pregnancy, and estimated date of delivery was 29 May 2008.  Concomitant medication included prenatal vitamins.  The patient experienced no adverse reactions.  Follow-up information was received on 14 December 2007, case reference number 0711091401.  It was reported that an ultrasound on 26 October 2007 showed no fetal heartbeat.  The patient had a miscarriage.  No further information regarding the event or the outcome is available.  The patient's medical history included high blood pressure at the end of her first pregnancy, as well as post-partum thyroid dysfunction.  She had an upper respiratory infection/cold from 10 September 2007 to 17 September 2007 and again from 15 October 2007 to 15 October 2007.  She had exposure to alcohol (wine, eight to ten drinks total) in September 2007 and caffeine (coffee, one to two cups per day) during August 2007 and September 2007.  Based upon the new information regarding the event of miscarriage, this case has been upgraded to serious.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Upper respiratory tract infection
Clinical narrative: Seriousness criteria: other - medically significant.  This case was reported by a health professional on 05 October 2007.  A 37-year-old female patient, with an allergy to penicillin, received an intramuscular injection of Adacel on 10 September 2007.  The patient, who was also a physician, had received a tetanus vaccine (manufacturer and lot number unknown) in January 2007.  She was pregnant at the time of vaccination, and the date of her last menstrual period was 23 August 2007.  Obstetric history included two previous pregnancies with normal, full-term deliveries.  An ultrasound on 02 October 2007 confirmed the pregnancy, and estimated date of delivery was 29 May 2008.  Concomitant medication included prenatal vitamins.  The patient experienced no adverse reactions.  Follow-up information was received on 14 December 2007, case reference number 0711091401.  It was reported that an ultrasound on 26 October 2007 showed no fetal heartbeat.  The patient had a miscarriage.  No further information regarding the event or the outcome is available.  The patient's medical history included high blood pressure at the end of her first pregnancy, as well as post-partum thyroid dysfunction.  She had an upper respiratory infection/cold from 10 September 2007 to 17 September 2007 and again from 15 October 2007 to 15 October 2007.  She had exposure to alcohol (wine, eight to ten drinks total) in September 2007 and caffeine (coffee, one to two cups per day) during August 2007 and September 2007.  Based upon the new information regarding the event of miscarriage, this case has been upgraded to serious.
Age: 12.0
Sex: F
Vaccine: TDAP
Symptoms: Hypotension, Nausea, Syncope, Visual disturbance
Clinical narrative: Initial report received on 14 December 2007 from the patient's parent. A 12-year old female, with no concurrent illnesses, pre-existing medical conditions, or use of other medications, had received a dose of Adacel (lot number "unknown") in the left deltoid on an "unknown" date. Minutes after receiving the vaccination, the patient became nauseated, saw spots and fainted to the floor. The patient spontaneously awoke within a minute; and the nurse stated the patient's blood pressure was low (blood pressure reading not reported). Blood pressure reading prior to the vaccination was not reported. No treatment for the adverse event was required. At the time of this report, the patient had recovered with "no sequelae."