Age: 69.0
Sex: M
Vaccine: COVID19
Symptoms: Lung neoplasm malignant, Pneumonia
Clinical narrative: lung cancer; pneumonia; This spontaneous case was reported by a consumer and describes the occurrence of LUNG NEOPLASM MALIGNANT (lung cancer) and PNEUMONIA (pneumonia) in a 70-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 038A21A and 026A21A) for COVID-19 vaccination.     The patient's past medical history included Ex-smoker (He was a previous smoker, but he hadn't smoked in the last 15- 20 years.).   On 08-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 05-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In 2021, the patient experienced PNEUMONIA (pneumonia) (seriousness criterion medically significant). In September 2021, the patient experienced LUNG NEOPLASM MALIGNANT (lung cancer) (seriousness criteria death and medically significant). The patient died on 14-Nov-2021. The reported cause of death was Lung cancer. It is unknown if an autopsy was performed. At the time of death, PNEUMONIA (pneumonia) outcome was unknown.            No Concomitant medications were provided. Treatment Information was not provided. She wanted to report the speed at which this cancer happened and grew. Patient had no symptoms, then cough in late August. They diagnosed him with pneumonia a week or two later. She hopes that by reporting this, Moderna would be able to find if the vaccine has a correlation with exacerbating the tumor or making it grow quicker. It was very aggressive. Patient was died in the hospital.  Company comment: This case concerns a 70-year-old, male patient with medical history of smoking(previous smoker, but he hadn't smoked in the last 15-20 years), who experienced the unexpected events of lung cancer(which ended fatally) and pneumonia. The event of pneumonia occurred approximately occurred approximately 5 months after the second dose of mRNA-1273, while lung cancer was diagnosed 6 months after second dose. As reported, the tumor was 12 centimeters, which was huge and the patient died of cancer 1 month later. The reporter (patient's daughter) was concerned if the vaccine correlated with exacerbating the tumor or making it grow quicker as it was very aggressive. Considering the size of tumour and advanced progression as well as patient's medical history of smoking causality for this event was assessed as not related per Company. Underlying cancer is also a confounding factor for event of pneumonia. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This case concerns a 70-year-old, male patient with medical history of smoking(previous smoker, but he hadn't smoked in the last 15-20 years), who experienced the unexpected events of lung cancer(which ended fatally) and pneumonia. The event of pneumonia occurred approximately occurred approximately 5 months after the second dose of mRNA-1273, while lung cancer was diagnosed 6 months after second dose. As reported, the tumor was 12 centimeters, which was huge and the patient died of cancer 1 month later. The reporter (patient's daughter) was concerned if the vaccine correlated with exacerbating the tumor or making it grow quicker as it was very aggressive. Considering the size of tumour and advanced progression as well as patient's medical history of smoking causality for this event was assessed as not related per Company. Underlying cancer is also a confounding factor for event of pneumonia. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Reported Cause(s) of Death: Lung cancer