Sex: M
Vaccine: VARZOS
Symptoms: Arthralgia, Injection site pain, Pain in extremity, Peripheral swelling, Sleep disorder
Clinical narrative: left sided shoulder pain; swelling down the left arm/has had to stop wearing his wedding ring due to the swelling; In the mornings he cannot close his hands without a lot of pain; trigger finger; the pain will wake him up at night unless he takes ASA.; Soreness at injection site; tendintus spreading down arm to Left Hand; This non-serious case was reported by a consumer and described the occurrence of injection site pain in a 72-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included carpal tunnel decompression (had carpal tunnel surgery, but this did not felt like carpal tunnel at all). Concurrent medical conditions included hypertension, stroke, diabetes and gastroesophageal reflux disease (GURD). Concomitant products included amlodipine, acetylsalicylic acid (Aspirin), losartan, metformin and omeprazole.   On 07-OCT-2023, the patient received the 2nd dose of Shingrix. On 13-DEC-2023, 67 days after receiving Shingrix, the patient experienced injection site pain (Verbatim: Soreness at injection site) and tendonitis (Verbatim: tendintus spreading down arm to Left Hand). On an unknown date, the patient experienced shoulder pain (Verbatim: left sided shoulder pain), swelling arm (Verbatim: swelling down the left arm/has had to stop wearing his wedding ring due to the swelling), pain in hand (Verbatim: In the mornings he cannot close his hands without a lot of pain), trigger finger (Verbatim: trigger finger) and nocturnal awakening (Verbatim: the pain will wake him up at night unless he takes ASA.). The patient was treated with meloxicam, capsaicin;menthol (Allevess), naproxen, ibuprofen, paracetamol (Tylenol) and acetylsalicylic acid (Asa). The outcome of the injection site pain, tendonitis, shoulder pain, swelling arm and pain in hand were not resolved and the outcome of the trigger finger and nocturnal awakening were not reported.   It was unknown if the reporter considered the injection site pain, tendonitis, shoulder pain, swelling arm, pain in hand, trigger finger and nocturnal awakening to be related to Shingrix.     It was unknown if the company considered the injection site pain, tendonitis, shoulder pain, swelling arm, pain in hand, trigger finger and nocturnal awakening to be related to Shingrix.   Additional Information: GSK Receipt Date: 30-APR-2024 This report was submitted via the online direct entry reporting system. The reporter reported that symptoms started after second Shingrix shot on 13th December 2023 and have persisted.  The patient also had left sided shoulder pain and swelling down the left arm and had to stop wearing his wedding ring due to the swelling.  He went to saw the doctor, and got a corticosteroid shot in his wrist at one point (greater than 3 months ago), which was not helpful.  In the mornings the patient could not close his hands without a lot of pain, and he did stated that he had trigger finger.  The patient was not having numbness or tingling.  Tried meloxicam, alleve, naproxen, ibuprofen, and tylenol without improvement. Found that two ASA before bed help with the pain. He had also been doing red light therapy, which he though had helped as well.  Pain was worst in the morning, progressively got better throughout the day.  The patient took a hot shower in the morning helped to loosen it up. The pain would wake him up at night unless he takes ASA.  The steroid shot in left arm was given which was effective for about 1 week in relieving pain and swelling but it then returned.  At the time of reporting was affecting both hands and left shoulder (soreness at injection site, tendonitis spreading down arm to left hand).