Sex: F
Vaccine: HPV4
Symptoms: Postural orthostatic tachycardia syndrome, Presyncope, Seizure, Smear cervix abnormal, Somnolence
Clinical narrative: "I wanted to sleep all day, every day"; Debilitating fatigue, breathing problems and unyielding heart palpitations caused her to take a leave from work; Debilitating fatigue, breathing problems and unyielding heart palpitations caused her to take a leave from work; dysautonomia; nausea; severe gastrointenstinal illnesses; abdominal bloating; POTS; she experienced twitching eyelids; difficulty swallowing; excruciating migrains; frequent urination; low blood pressure; neck pain; numbness in her fingers, feet, and face; she had CIN3 High grade dysplasia/In situ squamous cell carcinomas, the very ilness that Gardasil promises to prevent; fainting; all daily seizures diagnosed as Temporal Lobe Epilepsy; she had CIN3 High grade dysplasia/In situ squamous cell carcinomas, the very ilness that Gardasil promises to prevent; nearly to faint; Her third shot caused her to nearly faint and left her exhausted/debilitating fatigue; This spontaneous report was received from an other reporter and refers to a 24-year old female patient. There was no information about the patient's concurrent condition, concomitant medication or medically history provided.  On an unknown date in 2011, the patient was vaccinated with the third dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injection for prophylaxis (dose, route of administration, lot number and expiration date were not reported). Her third shot caused her to nearly faint and left her exhausted. On na unknown date the patient wanted to seep all day, every day, she felt debilitating fatigue, breathing problems and unyielding heart palpitations which caused her to take a leave from work.  On an unknown date (reported as within a month), the patient had amassed an inventory of adverse effects including dysautonomia, nausea, fainting, severe gastrointestinal illnesses, abdominal bloating, postural orthostatic tachycardia syndrome (POTS) and worst of all daily seizures diagnosed as temporal lobe epilepsy. She experienced twitching eyelids, difficulty swallowing, excruciating migraines, frequent urination, low blood pressure, neck pain and a frightening numbness in her fingers, feet, and face. The patient prayed to God and cried to God but nothing helped her. The patient's life became a horror movie.  On an unspecified date in November 2012, biofeedback miraculously brought her seizures under control and allowed her to return to work.   On an unknown date in October 2016, the patient had performed biopsy and abnormal pap smear with result of cervical intraepithelial neoplasia stage 3 (ClN3) high grade dysplasia / in situ squamous cell carcinomas, the illness that quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) promises to prevent. The patient's doctor told her she would die without surgery.  The patient wanted to healing it first instead of cutting cervix out. The patient balanced her health using a ketogenic diet to starved the pathogens by cutting out their food supply, which was sugar/grains/legumes/fructose. She boosted her immune system with L-lysine and Beta-Glucan, biofeedback, and exercise. The patient's seizures were gone and her cervix healed completely.   The outcome of presyncope, drug ineffective, hypoaesthesia, neck pain, hypotension, pollakiuria, migraine, dysphagia, blepharospasm, postural orthostatic tachycardia syndrome, abdominal distension, gastrointestinal disorder, syncope, nausea, autonomic nervous system imbalance, palpitations, dyspnoea, somnolence and fatigue was unknown. The outcome of temporal lobe epilepsy and cervix carcinoma stage 3 was reported as recovered.  The relatedness between presyncope, fatigue and quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) was related.   The causality assessment for drug ineffective, hypoaesthesia, neck pain, hypotension, pollakiuria, migraine, dysphagia, blepharospasm, postural orthostatic tachycardia syndrome, abdominal distension, gastrointestinal disorder, syncope, nausea, autonomic nervous system imbalance, palpitations, dyspnoea, somnolence, temporal lobe epilepsy and "CIN3 High grade dysplasia/In situ squamous cell carcinomas" was not provided.  Upon internal review, the events of "CIN3 High grade dysplasia/In situ squamous cell carcinomas", fainting and temporal lobe epilepsy were determined to be medically significant.