Age: 65.0
Sex: F
Vaccine: COVID19, FLU3
Symptoms: Arthralgia, Complex regional pain syndrome, Fatigue, Hypoaesthesia, Joint swelling
Clinical narrative: complex regional pain syndrome; hypoaesthesia; joint swelling; sleep disorder; Arthralgia; Fatigue; Pain; pain in extremity; paraesthesia; pyrexia; Initial information received on 09-Dec-2024 regarding an unsolicited valid  non-serious case received from a consumer/Non-Healthcare Professional from Novavax as courtesy case.  This case involves a 65 years old female patient who experienced complex regional pain syndrome, hypoaesthesia, joint swelling, sleep disorder, arthralgia, fatigue, pain, pain in extremity, paraesthesia and pyrexia after receiving Novavax COVID-19 Vaccine and influenza USP trival A-B high dose subvirion vaccine [Fluzone High Dose].  The patient's past medical history included Wrist fracture on 12-Sep-2024 , Hypothyroidism, Osteoporosis, Seasonal allergy and Dust allergy. The patient's past medical treatment(s), vaccination(s) and family history were not provided. At the time of the event, the patient had ongoing Tinnitus.  Concomitant medications included Levothyroxine; Alendronate sodium; Calcium carbonate; Vitamin d nos; and Ascorbic acid, Lecithin, Medium-chain triglycerides (Liposomal vitamin c) for Product used for unknown indication.  On 24-Sep-2024, the patient received unknown dose of suspect influenza USP trival A-B high dose subvirion vaccine, Suspension for injection in pre-filled syringe and Novavax COVID-19 Vaccine injection not produced by Sanofi Pasteur (lot number and expiry date not reported) both via intramuscular route in in the same arm, the arm that I had broken for COVID-19 immunization.  There will be no information available on the batch number for this case.  On 30-Oct-2024 the patient developed complex regional pain syndrome, hypoaesthesia, joint swelling,  sleep disorder, arthralgia, fatigue, pain, pain in extremity, paresthesia and pyrexia (latency: 1 month 6 days).  Reportedly I broke my wrist .. distal radial comminuted fracture, September 12th, 2024. That day in the ER they used a hematoma block and realign the fracture. They put me in a sugar tong splint. On September 24th, I got a flu and a COVID vaccine in the same arm, the arm that I had broken. On October 2nd the sugar tong splint was removed and the orthopedist put me in a ""BOA"" cast/splint. The day that I got it on I began to experience numbness, tingling, and searing pain that shot from my wrist into my hand in both the radial and ulnar distributions. This continued, mostly at night, in spite of adjustments to the BOA. This past Wednesday, October 30th, the BOA was removed, and I was giving a splint to wear with instructions to mostly not wear it. For the next 3 days I had horrific, searing, burning, explosive pain, that seem to start in my palm and spread to my fingers. It kept me up for a couple of nights. I've had a couple of doctors look at it, most think that it is reflex sympathetic dystrophy, as it doesn't fit any anatomical pattern. My wrist is also more swollen than it ought to be at this point in the healing process. X-rays look good, however. I'm only telling you all this because it is the same arm where I got the flu and COVID vaccine. I have never had anything like this before. I am not taking any medications for it because I have tinnitus that was caused by NSAIDs, so I refuse to take those again, and I'm not going to take anything more than that because of the risks involved. Today the pain is not as bad. I think that I have found that the actions that I take and the way I hold my wrist when I type is what sets off the really horrible pain, so I have been using my wrist to do other things but not to type since yesterday afternoon. That may be why the pain is better today. I agree that it is more likely related to the fracture and perhaps a problem with the BOA placement or fitting, or some other fracture related issue, but it is, coincidentally, the same arm I got the COVID vaccine in. I've had all of my recommended COVID vaccines up to this point and have not had any issues other than fever and fatigue for a couple of days afterwards. As a matter of fact, this time I got the NovaVax vaccine, and I still had a fever and fatigue but it lasted a little less than 24 hours whereas The MRA vaccines gave me symptoms for 2 to 3 days  Relevant laboratory test results included: X-ray - On an unknown date:  [X-rays look good].  Action taken: Not applicable.  It was not reported if the patient received a corrective treatment for all the events.  At time of reporting, the outcome was Not Recovered / Not Resolved for all the events.