Sex: M
Vaccine: MENB, MNQ
Symptoms: Cellulitis, Chills, Hyperhidrosis, Pyrexia
Clinical narrative: Initial information received on 22-Oct-2018 regarding an unsolicited valid serious case received from a nurse via other company (Pfizer). This case involves a 17 years old male patient who experienced left arm cellulitis, fever, chills and sweat, while he received vaccines TRUMENBA and MENACTRA. The patients past medical history and family history were not provided. The patient did not receive any concomitant medication. On 24-Sep-2018, the patient received injection of suspect MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE lot number, expiry date and dose not reported via unknown route in unknown administration site. On 24-Sep-2018, the patient received a first dose of suspect TRUMENBA not produced by Sanofi Pasteur lot W09937, expiry date Jan 2020 via unknown route in the left arm. On 25-Sep-2018, the patient developed a serious left arm cellulitis (cellulitis) one day following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of TRUMENBA. This event was assessed as Important medical event. On 24-Sep-2018, the patient developed a non-serious fever (pyrexia) same day, late night following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of TRUMENBA. On 24-Sep-2018, the patient developed a non-serious chills same day, late night following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of TRUMENBA. On 24-Sep-2018, the patient developed a non-serious sweat (hyperhidrosis) same day, late night following the administration of MENINGOCOCCAL A-C-Y-W135 (D CONJ) VACCINE and following the administration of TRUMENBA. Relevant laboratory test results included- Body temperature - On 25-Sep-2018: 97.6 Relevant tests were not reported. Final diagnosis was sweat, chills, fever and left arm cellulitis. The patient was treated with Keflex- 500mg capsule one capsule twice daily by mouth, Prednisone- A weaning dose of 30mg, 20mg and 10mg for 3 days each. These are tablets the patient took by mouth. Benadryl-Over the counter dose of 25mg to 50mg as needed. The patient outcome is reported as Recovered / Resolved on an unknown date for fever, as Recovered / Resolved on an unknown date for chills, as Recovered / Resolved on an unknown date for sweat and as Recovered / Resolved on an unknown date for left arm cellulitis. The reporter assessed the causal relationship with suspect vaccines as Related. List of documents held by sender- none.; Sender's Comments: This case concerns a 17-year-old patient who developed left arm cellulitis, fever, chills and sweat after vaccination with TRUMENBA and MENACTRA. The time to onset is compatible. However, there is no information regarding the patient's condition at the time of vaccination and the etiology for cellulitis. Cellulitis occurred at other company vaccinated arm. There is a possibility that the infection is due to a faulty vaccination procedure that introduced skin organisms into the patient. Moreover, multiple vaccine use preceded the events. Based upon the reported information, the role of an individual vaccine cannot be assessed.