Age: 46.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Menopausal symptoms, Menstrual disorder, Myalgia, Pyrexia, Swelling
Clinical narrative: The patient had an abrupt onset of postmenopausal symptoms.; Patient noticed that she no longer had a menstrual cycle.; The swelling was most pronounced in her right knee and right groin.; The swelling was most pronounced in right knee and right groin.; Lower extremity severe and more swelling around lymph nodes, groin and knees; Had arthritic body pain, was most pronounced around pelvis and knees; low grade fever,most persistent for 48 hours but lasted for 5 days.; headache most persistent for 48 hours but lasted for 5 days.; chills which were most persistent for 48 hours but lasted for 5 days.; body aches which were most persistent for 48 hours but lasted for 5 days.; This spontaneous case was reported by a nurse and describes the occurrence of MENOPAUSAL SYMPTOMS (The patient had an abrupt onset of postmenopausal symptoms.), MENSTRUAL DISORDER (Patient noticed that she no longer had a menstrual cycle.), JOINT SWELLING (The swelling was most pronounced in her right knee and right groin.), SWELLING (The swelling was most pronounced in right knee and right groin.) and LYMPHADENOPATHY (Lower extremity severe and more swelling around lymph nodes, groin and knees) in a 46-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013M20A and 029L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 14-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 11-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 11-Feb-2021, the patient experienced MENOPAUSAL SYMPTOMS (The patient had an abrupt onset of postmenopausal symptoms.), MENSTRUAL DISORDER (Patient noticed that she no longer had a menstrual cycle.) and MYALGIA (body aches which were most persistent for 48 hours but lasted for 5 days.). 11-Feb-2021, the patient experienced JOINT SWELLING (The swelling was most pronounced in her right knee and right groin.), SWELLING (The swelling was most pronounced in right knee and right groin.), LYMPHADENOPATHY (Lower extremity severe and more swelling around lymph nodes, groin and knees), ARTHRALGIA (Had arthritic body pain, was most pronounced around pelvis and knees), PYREXIA (low grade fever,most persistent for 48 hours but lasted for 5 days.), HEADACHE (headache most persistent for 48 hours but lasted for 5 days.) and CHILLS (chills which were most persistent for 48 hours but lasted for 5 days.). At the time of the report, MENOPAUSAL SYMPTOMS (The patient had an abrupt onset of postmenopausal symptoms.), MENSTRUAL DISORDER (Patient noticed that she no longer had a menstrual cycle.), JOINT SWELLING (The swelling was most pronounced in her right knee and right groin.), SWELLING (The swelling was most pronounced in right knee and right groin.), LYMPHADENOPATHY (Lower extremity severe and more swelling around lymph nodes, groin and knees) and ARTHRALGIA (Had arthritic body pain, was most pronounced around pelvis and knees) outcome was unknown and PYREXIA (low grade fever,most persistent for 48 hours but lasted for 5 days.), HEADACHE (headache most persistent for 48 hours but lasted for 5 days.), CHILLS (chills which were most persistent for 48 hours but lasted for 5 days.) and MYALGIA (body aches which were most persistent for 48 hours but lasted for 5 days.) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant medications were reported.  It was reported that the patient reported the Adverse reaction of same reaction after the first vaccination occurred after second vaccination as well but the swelling and pain were much more severe. The patient never had a significant gynecological history prior to this event. No treatment details were reported.   This case was linked to MOD-2022-650998, MOD-2022-650966 (Patient Link).