Age: 70.0
Sex: F
Vaccine: COVID19
Symptoms: Blood pressure measurement, Chest discomfort, Chest pain, Hypertension, Pulmonary thrombosis
Clinical narrative: Blood clot in lung diagnosed, worry related to blood thinner use; Chest pains; Chest "didn't feel right"; Blood pressure increased; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PULMONARY THROMBOSIS (Blood clot in lung diagnosed, worry related to blood thinner use), CHEST PAIN (Chest pains) and CHEST DISCOMFORT (Chest "didn't feel right") in a 70-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 021B21A and 047A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 in November 2020. Concurrent medical conditions included Cholesterol blood excessive, Hypertension and Hyperlipidemia. Concomitant products included APIXABAN (ELIQUIS), CELECOXIB (CELEBREX), METOPROLOL SUCCINATE and LOSARTAN POTASSIUM for an unknown indication.   On 25-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 22-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 25-Apr-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced CHEST DISCOMFORT (Chest "didn't feel right") (seriousness criterion hospitalization). On 28-Apr-2021, the patient experienced PULMONARY THROMBOSIS (Blood clot in lung diagnosed, worry related to blood thinner use) (seriousness criteria hospitalization, medically significant and life threatening), CHEST PAIN (Chest pains) (seriousness criterion hospitalization) and HYPERTENSION (Blood pressure increased). The patient was hospitalized on 28-Apr-2021 due to CHEST PAIN and PULMONARY THROMBOSIS. At the time of the report, PULMONARY THROMBOSIS (Blood clot in lung diagnosed, worry related to blood thinner use), CHEST PAIN (Chest pains), CHEST DISCOMFORT (Chest "didn't feel right") and HYPERTENSION (Blood pressure increased) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 28-Apr-2021, Blood pressure measurement: increased (High) Increased.         Concomitant medication included high cholesterol drug.    On 28 Apr 2021, post second dose of vaccination patient experienced chest pains and went to emergency room. Patient reports a chest scan, chest X-ray, bloodwork, EKG, echocardiogram, and various tests were performed at the hospital. Patient was diagnosed with a blood clot in lungs. Patient reports being hospitalized several days and doctors indicated "she dodged a bullet". Patient reports the treating physicians could not determine the cause of the clot, nor determine if it was vaccine related. Patient reports concomitant medication, losartan dose was recently increased from 50mg to 100mg once daily. Patient attributes that the increased blood pressure was the worry related to being placed on blood thinners [Eliquis].  Treatment information included eliquis.  Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.   This case was linked to MOD-2021-138094 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.