Age: 61.0
Sex: F
Vaccine: COVID19, VARZOS
Symptoms: Chronic kidney disease, Laboratory test, Myalgia, Neuropathy peripheral, Paraesthesia
Clinical narrative: Neuropathy; stage 1 chronic kidney disease; tingling in feet/vibrations in feet; severe muscle pain in her arms and legs; This serious case was reported by a consumer via call center representative and described the occurrence of neuropathy in a 64-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included COVID-19 vaccine for prophylaxis.   Concurrent medical conditions included thyroid disorder (it was not clarified or specified), chronic lymphocytic leukemia, osteoporosis and osteoarthritis. Additional patient notes included patient did not had shingles in the past and not had diabetes.   In MAR-2021, the patient received the 1st dose of Shingrix. On an unknown date, the patient received COVID-19 vaccine. On an unknown date, several days after receiving Shingrix, the patient experienced neuropathy (Verbatim: Neuropathy) (serious criteria GSK medically significant), chronic kidney disease stage 1 (Verbatim: stage 1 chronic kidney disease) (serious criteria GSK medically significant), tingling of extremity (Verbatim: tingling in feet/vibrations in feet) and myalgia upper extremities (Verbatim: severe muscle pain in her arms and legs). The outcome of the neuropathy and tingling of extremity were not resolved and the outcome of the chronic kidney disease stage 1 was unknown and the outcome of the myalgia upper extremities was resolving.   It was unknown if the reporter considered the neuropathy, chronic kidney disease stage 1, tingling of extremity and myalgia upper extremities to be related to Shingrix.     It was unknown if the company considered the neuropathy, chronic kidney disease stage 1, tingling of extremity and myalgia upper extremities to be related to Shingrix.   Additional Information: GSK Receipt Date: 24-DEC-2023 and 29-DEC-2023 The patient self-reported this case. The patient received the first dose of Shingrix in mid-March 2021 and Within a few days, the patient began experiencing severe muscle pain in her arms and legs, tingling and vibrations in her feet.  the next several weeks had severe muscle pain, it felt like someone was pulling the muscles off my bone. The tingling in feet also started and had continued since. The reporter asked if this tingling in feet would stay forever. The patient had the test for neuropathy, and it was confirmed. The patient was scared and was terrified of getting shingles, but now this on top of everything else she had to deal with too much. The reporter asked if the symptoms would get worse. The patient stated that if she had known this would happen, she would had never gotten the vaccine. The patient was diagnosed with neuropathy. The patient reported that Stage 1 chronic kidney disease developed after receiving Shingrix. The patient stated that she received a COVID vaccine around the same time as the first dose of Shingrix. The patient reported that the pain in her muscles were much better, but the tingling in her feet remained, some days it was minimal and other days it felt like she had a tens unit on her feet. The patient did receive the second dose of Shingrix, but the described events started after the first dose. The reporter consented to follow up. On an unknown date, several days after receiving COVID-19 vaccine, the patient experienced neuropathy, chronic kidney disease stage 1, tingling of extremity and myalgia upper extremities. It was unknown if the reporter considered the neuropathy, chronic kidney disease stage 1, tingling of extremity and myalgia upper extremities to be related to Covid 19 vaccine.