Age: 50.0
Sex: M
Vaccine: VARZOS, VARZOS
Symptoms: Injection site erythema, Injection site swelling, Myalgia, Nausea, Pyrexia
Clinical narrative: Acute Vestibular Neuritis Attack; feeling as if someone hit him with a truck; could barely walk; trouble with his eye; Reactivation of Shingles; Injection Site Mark; Fever; Muscle Pain; Joint Pain; Soreness; This case was reported by a consumer via call center representative and described the occurrence of shingles in a 50-year-old male patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included shingles, vestibular neuronitis (severe episode prior to September 2019 was approximately 9 years ago.) and chickenpox.   On 12th June 2019, the patient received the 1st dose of Shingrix (intramuscular). On 12th June 2019, less than a day after receiving Shingrix, the patient experienced fever, muscle pain, joint pain, pain and feeling abnormal. In June 2019, the patient experienced shingles, walking difficulty and eye disorder. In September 2019, the patient experienced vestibular neuronitis. On an unknown date, the patient experienced injection site reaction. The patient was treated with valaciclovir hydrochloride (Valtrex). On an unknown date, the outcome of the shingles was not recovered/not resolved and the outcome of the injection site reaction, fever, muscle pain, joint pain and pain were recovered/resolved and the outcome of the vestibular neuronitis, walking difficulty, eye disorder and feeling abnormal were unknown.   It was unknown if the reporter considered the shingles, injection site reaction, fever, muscle pain, joint pain, pain, vestibular neuronitis, walking difficulty, eye disorder and feeling abnormal to be related to Shingrix.  Additional case details were reported as follows: The patient reported historically having bouts (or multiple instances) of acute vestibular neuritis attacks believed to be triggered by a herpes strain of virus and reported his last severe episode prior to September 2019 was approximately 9 years ago. The patient received vaccine in left deltoid in the late morning on 12th June 2019. Around 5 pm, on the same day he started running a fever and had muscle and joint pain described as feeling as if someone hit him with a truck.  Less than a week after vaccination, the patient could barely walk.  He stated that, the severe part of these symptoms resolved in approximately 48 hours and he felt mostly normal after an additional 48 hours elapsed. The patient reported soreness in his arm lasted a little longer and an injection site mark was visible for an unspecified number of months.  Approximately 1 week following vaccination patient trouble with his eye; however, on 11th July 2019 was when he visited his ophthalmologist when it was diagnosed he had reactivation of shingles in the trigeminal nerve in his eye. The patient received a low dose of Valtrex for an unspecified time period at an unknown date. Lastly, between 3 and 4 months after vaccination, the patient had an acute vestibular neuritis attack in September 2019 and mentioned no way to determine this if related to shingles vaccine or not. The patient wishes for warnings for Shingrix that vaccine could cause reactivation. The patient mentioned his doctor would contact medical information for more information and that the reaction was already reported to VAERS.  The patient would call back later with more information event information. The patient reported not likely he would receive 2nd dose of Shingrix that was due soon. The reporter consent to follow up.