Sex: M
Vaccine: VARZOS
Symptoms: Condition aggravated, Herpes simplex test positive, Herpes zoster, Nerve injury, Ophthalmic herpes zoster
Clinical narrative: Shingles / into eye; Double dose vaccine / he got it / One year later he got shingles so bad / covered from hairline, accross eyebrow, eyelid and into the eye; Scabs have healed; Still has nerve damage with daily attacks; Still has nerve damage with daily attacks; Double dose vaccine / he got it / One year later he got shingles so bad / suspected vaccination failure; This case was reported by a consumer via interactive digital media and described the occurrence of suspected vaccination failure in a male patient who received Herpes zoster (Shingles vaccine) for prophylaxis.   Co-suspect products included Herpes zoster (Shingles vaccine) for prophylaxis.   The patient's past medical history included shingles (had twice, pretty bad each time). Previously administered products included Shingles vaccine (one dose vaccine received on an unknown date) and Acyclovir (took for years because the one dose vaccine would not work for him and was told he did not need acyclovir and to stop taking it).   On an unknown date, the patient received the 1st dose of Shingles vaccine and the 2nd dose of Shingles vaccine. On 9th May 2020, 1 year after receiving Shingles vaccine and Shingles vaccine, the patient experienced vaccination failure (serious criteria GSK medically significant) and neurological symptom. On 9th May 2021, the patient experienced ophthalmic herpes zoster (serious criteria GSK medically significant), shingles, scab and nerve damage. On an unknown date, the outcome of the vaccination failure was unknown and the outcome of the ophthalmic herpes zoster, shingles and scab were recovered/resolved and the outcome of the nerve damage and neurological symptom were not recovered/not resolved.   It was unknown if the reporter considered the vaccination failure, ophthalmic herpes zoster, shingles, scab, nerve damage and neurological symptom to be related to Shingles vaccine and Shingles vaccine.  Additional details were reported as follows: This case was reported by patient's wife. The age at vaccination was not reported. In 2019, the patient received the both doses of Shingles vaccine (double dose vaccine). One year later (the day before Mother's Day 2020), the patient got shingles so bad he was covered from hairline, across eyebrow, eyelid and into eye. The reporter stated that even though the scabs had healed the patient still had nerve damage with daily attacks and was lucky that his eye has healed with no significant damage. The reporter mentioned that during treatment they had learned that there were lots of people like this patient. This case was considered as suspected vaccination failure as detail regarding laboratory test confirming herpes zoster was unknown at the time of reporting. The follow-up would not possible as no contact details were available. This case had been linked with US2021AMR101272 and US2021AMR104433, reported by same reporter.; Sender's Comments:  US-GLAXOSMITHKLINE-US2021AMR101272:Same reporter. Reporter's own case. US-GLAXOSMITHKLINE-US2021AMR104433:Same reporter. Master case: "lots of people"