Age: 40.0
Sex: F
Vaccine: COVID19
Symptoms: Central nervous system vasculitis, Cerebral ischaemia, Computerised tomogram, Immunisation, Intracranial pressure increased
Clinical narrative: intracranial hypertension; small vessel ischemic changes; vasculitis; the booster dose on 17Sep2021; body aches; headache/ migraine; This is a spontaneous report from a contactable consumer reported for herself. A 40-year-old female patient received bnt162b2 (COMIRNATY), dose 3 via an unspecified route of administration on 17Sep2021 (Lot Number: FC3183) as DOSE 3 (BOOSTER), SINGLE for COVID-19 immunisation at the age of 40 years old. Medical history included ongoing addison's disease. Concomitant medication(s) included pneumococcal vaccine (PNEUMOCOCCAL VACCINE) taken for immunisation on 13Sep2021; hydrocortisone (HYDROCORTISONE) taken for addison's disease; fludrocortisone (FLUDROCORTISONE) taken for addison's disease.  The patient previously received first dose of BNT162B2 on 18Dec2020 (Lot Number: EJ1685, Expiry: Mar2021) and received 2nd dose of BNT162B2 on 07Jan2021 (Lot Number: EL3248, Expiry: Apr2021) for COVID-19 immunisation both at the age of 39 years old, and both experienced body aches, headache, chills, low grade fever.  The patient experienced the booster dose on 17sep2021 with outcome of unknown, vasculitis on 01Oct2021 with outcome of unknown, intracranial hypertension on 20Oct2021 with outcome of unknown, small vessel ischemic changes on 01Oct2021 with outcome of unknown, body aches on 17Sep2021 with outcome of recovered on 18Sep2021, headache/ migraine on 17Sep2021 with outcome of not recovered.     The clinical course was reported as follows: She had her 3rd dose on Friday, 17Sep2021, and with her other two vaccines she had the normal side effects like body aches, headache, chills and low grade fever. Everything went away in 24 hours and it was no biggie. She thought that she just had a strong immune system but then with the 3rd dose she had it in the morning and went to work and then before her shift had ended she had body aches and a headache as well. 24 hours afterwards her body aches went away but she has had a pretty severe headache/ migraine ever since and it has never gone away. It doesnt come and go, it has been there all day every day, and it is constant. It has been 6 weeks. The side effects after her 3rd dose started in less than 8 hours afterwards.  She did get her pneumonia shot that Monday before she got her COVID vaccine, confirmed to be on 13Sep2021. Her physician said that it was fine to do them that closely spaced and the caller didnt think that anything was wrong with. In this whole journey of trying to figure this out because she has has no history of having headaches or migraines, she ended up having a CT scan and then she also had 1 MRI that showed possible intracranial hypertension and then she had a 2nd MRI that was looking for blood clots, there wasnt any, but it also showed intracranial hypertension. She has no history of hypertension and she actually has to take medications to keep her blood pressure up. Inquired for further details on the medications that she has to take to keep her blood pressure up and she states that she has Addisons disease and takes hydrocortisone as well as fludrocortisone because it also helps keep her electrolytes in balance to help maintain her blood pressure, she started them both 20 years ago. Inquired for dates of the CT scan and the 2 MRIs and she states that her had her 2nd MRI she believes on 27Oct2021 and the 1st on 20Oct2021 and both showed the intracranial hypertension. Her 1st MRI was with and without contrast. Now she is waiting to see an eye doctor because they apparently can see it behind the eyes and she is going to do that in a week and a half and then she has to meet with a neurologist after that to maybe do an LP to drain spinal fluid to try to relieve the pressure in her brain. Inquired for results of her CT scan and she states that it didnt come back normal there were something about non specific changes but she needs to double check. The CT was without contrast and it says that there were scattered non-spatial subcortical in the bilateral frontal lobes greater than the expected age, nonspecific and then it also said there were early small vessel ischemic changes and vasculitis to include white mater changes consistent with migraines, but she has never had migraines in her entire life until 17Sep2021. In her mind these are all cute changes. She had her CT scan on 01Oct2021, Oct2021 was a very expensive month for her.