Age: 53.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Heart rate, Heart rate increased, Hypertension, Oesophageal discomfort, Oesophageal manometry
Clinical narrative: UNABLE TO EAT; FELT LIKE SOMETHING STUCK IN ESOPHAGUS; HEART RATE ELEVATED (200 BPM); HIGH BLOOD PRESSURE; CHEST PRESSURE / CHEST TIGHTNESS (FREQUENT); SEVERE UPPER ABDOMINAL PAIN; CHEST PAIN; RASH SPREAD TO BACK, CHEST, ARMS AND LEGS; This spontaneous report received from a patient concerned a 53 year old female of unknown ethnicity. The patient's height, and weight were not reported. The patient's past medical history included: rash spread all over body and concurrent conditions included: non-smoker, and non-alcohol user, and other pre-existing medical conditions included: The patient had no known drug allergies and no history of drug abuse or illicit drug usage. The patient experienced rash that spread all over body when treated with varicella zoster vaccine on 08-NOV-2020 for prophylactic vaccination and was previously treated with prednisone for rash that spread all over body.  The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 043A21A, expiry: UNKNOWN) dose was not reported, 1 total, administered on 03-APR-2021 to left arm between noon to 12:30 for prophylactic vaccination. No concomitant medications were reported.  On 06-APR-2021 (after 3 days of vaccination), patient experienced the rash that spread to back, chest, arms and legs. On 18-APR-2021, patient had chest pain, elevated heart rate (200 bpm) and chest pressure and tightness. That symptoms were lasted for 4-5 hours. The patient also experienced severe upper abdominal pain. On 19-APR-2021, chest pain and elevated heart rate resulted into emergency room. The patient had blood pressure 200/117 mmHg. The EKG did not find anything. Those symptoms were for that whole week. The patient was experiencing the high blood pressure and chest tightness every other day. Over the month of APR-2021 and MAY-2021, patient visited the emergency room 10 times with those similar symptoms. On an unspecified date, patient felt like something was stuck into her esophagus and was experiencing severe abdominal pain. The patient was unable to eat. The patient went to the cardiologist for ECG, Zio patch and stress test. All tests were resulted as normal. Patient visited gastroenterologist and had endoscopy and manometry. Both tests were resulted as normal. Until JUN-2021, she began to feel better and good. The chest pressure, increased blood pressure and upper abdominal pain was subsided and not as intense. The patient was on blood pressure medications with controlled blood pressure now. She was still experiencing the chest pressure and upper abdominal pain. On 27-OCT-2021, primary care physician had tested her cortisol level and prescribed patient with dexamethasone to get her cortisol levels drawn. The patient felt fine after taking dexamethasone and was waiting for cortisol test results. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient was recovering from rash spread to back, chest, arms and legs, chest pain, heart rate elevated (200 bpm), high blood pressure, severe upper abdominal pain, and chest pressure / chest tightness (frequent), and the outcome of unable to eat and felt like something stuck in esophagus was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0: 20211059445 -Covid-19 vaccine ad26.cov2.s-  Heart rate elevated (200 bpm), High blood pressure. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).