Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Abdominal pain, Chills, Condition aggravated, Feeling cold, Flatulence
Clinical narrative: hyperventilating; tingling in her hands; panic attack; Chills; she felt cold; gas; abdominal pain; nausea; This serious case was reported by a consumer via program and described the occurrence of feeling cold in a 63-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included panic attack. Concurrent medical conditions included reaction to sulphite.   On 21-DEC-2023, the patient received the 1st dose of Shingrix (intramuscular, unknown arm). On 21-DEC-2023, 9 hrs after receiving Shingrix, the patient experienced feeling cold (Verbatim: she felt cold) (serious criteria other: serious as per reporter), chills (Verbatim: Chills) (serious criteria other: serious as per reporter), gas (Verbatim: gas) (serious criteria other: serious as per reporter), abdominal pain (Verbatim: abdominal pain) (serious criteria other: serious as per reporter) and nausea (Verbatim: nausea) (serious criteria other: serious as per reporter). On 22-DEC-2023, the patient experienced panic attack (Verbatim: panic attack) (serious criteria other: serious as per reporter), hyperventilation (Verbatim: hyperventilating) (serious criteria other: serious as per reporter) and tingling of extremity (Verbatim: tingling in her hands) (serious criteria other: serious as per reporter). The patient was treated with acrivastine (Benadryl) and ondansetron (Zofran). On 22-DEC-2023, the outcome of the feeling cold, chills, gas, abdominal pain and nausea were resolved (duration 1 day) and the outcome of the panic attack, hyperventilation and tingling of extremity were resolved.   It was unknown if the reporter considered the feeling cold, panic attack, chills, hyperventilation, tingling of extremity, gas, abdominal pain and nausea to be related to Shingrix.     It was unknown if the company considered the feeling cold, panic attack, chills, hyperventilation, tingling of extremity, gas, abdominal pain and nausea to be related to Shingrix.   Additional Information: GSK Receipt date: 22-DEC-2023 The patient self-reported this case.  Patient stated she had a reaction to the Shingrix vaccine and ended up in the hospital and reporter had medical questions about product and vaccine ingredients. She received her first dose yesterday (day before reporting), about nine hours later, still on 21 December 2023, she felt cold and was unable to warm up with a hot shower, bundling in blankets and a heating pad.  At that time, she also had chills, nausea, gas and abdominal pain.  About 14 hours after vaccination, on 22 December 2023 she had a panic attack, tingling in her hands and started hyperventilating.  She tried breathing into a brown paper bag, as she usually does with a panic attack, but without success.  She went to the Emergency Room and received Benadryl, Zofran and a steroid. She slept and woke up feeling better with all effects resolved and she was not admitted to the hospital.  The case US2023179250 was identified as duplicate of case US2023179160. All future correspondence would be added in case US2023179160, which stands as case of record for this patient and the case US2023179250 would be deleted. The reporter did not consent to follow-up.