Age: 1.25
Sex: M
Vaccine: MMR, MMR, UNK, MMR
Symptoms: Lacrimation increased, Ocular hyperaemia, Pyrexia, Rash, Rhinorrhoea
Clinical narrative: 2 patients developed prolonged symptoms of measles like rashes and fever after receiving MMR II vaccines with the same lot; 2 patients developed prolonged symptoms of measles like rashes and fever after receiving MMR II vaccines with the same lot; Herpanginia/enterovirus; Upper respiratory illness; Fever; This spontaneous report was received from a Nurse and refers to 2 patients of unknown age and gender.   The patients' medical history, concurrent conditions, concomitant therapies, psat drug reactions and allergies were not reported.   On an unknown date, the patients were vaccinated with Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II), administered as prophylaxis (lot number Y015995 has been verified to be valid for Measles, Mumps, and Rubella [Wistar RA 27-3] Virus Vaccine, Live [M-M-R II], expiration date 24-SEP-2026; formulation, dose, vaccination scheme frequency, route of administration and anatomical site of injection were not reported), which was reconstituted with sterile diluent (BAXTER STERILE DILUENT) (lot number and expiration date were not provided).  On an unknown date, the 2 patients developed prolonged symptoms of measles like rashes (Rash morbilliform) and fever (pyrexia) after receiving Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II) vaccines with the same lot. The nurse mentioned that the patients went to a health department to get tested for measles (results not provided).  At the reporting time, the outcome of both events were not reported.   The causal relationship between Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II) and sterile diluent (BAXTER STERILE DILUENTE) regarding the events of Rash morbilliform and pyrexia was not provided.   No further information provided.   This report was considered as non-valid due to the lack of patient´s identifiers and as it concerned 2 patients.   This is an amendment report. AE QIR required field was updated from ¨Yes¨ to ¨No¨ for Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II).   Follow up information was received from a Nurse on 14-May-2025.   This spontaneous report was received from a Nurse and refers to a 16-month-old male patient.   On 15-Apr-2025, the patient was vaccinated with Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II), administered subcutaneously in the left thigh as prophylaxis (lot number Y015995 has been verified to be valid for Measles, Mumps, and Rubella [Wistar RA 27-3] Virus Vaccine, Live [M-M-R II], expiration date 24-SEP-2026; formulation, dose and vaccination scheme frequency were not reported), which was reconstituted with sterile diluent (BAXTER STERILE DILUENT) (lot number and expiration date were not provided). On that same the date, the patient was also vaccinated with HIB vaccine, administered intramuscularly in the left vastus lateralis (lot number: UK113AB, expiration date: 30-SEP-2025; formulation, dose and vaccination scheme frequency were not reported).   On 21-Apr-2025 (conflicting information, also reported as 22-Apr-2025) (outcome was reported as recovered), the patient returned to office with complains of fever (pyrexia). On 22-Apr-2025, the patient was diagnosed with upper respiratory illness (Respiratory disorder) and was prescribed amoxicillin.  On 24-Apr-2025, the patient was seen due to a fever (conflicting information, also reported as continued fever) and developed prolonged symptoms of measles like rashes (Rash morbilliform). On this same date, the patient was diagnosed with Herpanginia/enterovirus (likely secondary MMR fever or rash).  On 26-Apr-2025, the patient returned to office with worsening rash and an ongoing fever. On that same date, a PCR measles swab was positive.  At the reporting time, the outcome of the events herpangina and respiratory disorder were not reported. The outcome for the events rash morbilliform and pyrexia were reported as recovering.   The causal relationship between Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (M-M-R II) and sterile diluent (BAXTER STERILE DILUENTE) regarding the events of Rash morbilliform and pyrexia was reported as related. The causal relationship between the events and HIB vaccine, was not provided.; Sender's Comments: Priority : 5 , Is case serious : No , MNSC number : 02801836-02801834 , CLIC number : , ESTAR number : , IRMS number : 500UW00000aLA7kYAG|14052025230025|6409 , Central date : 2025-05-15 , Classification : DMC, Attachment description : NSC Call , Safety case number : 2284529 , MNSC case number : 02801836 , MNSC interaction number : 02801834 , Integration log UniqueID : 500UW00000aLA7kYAG|14052025230025|6409 , Service cloud CaseID : 500UW00000aLA7kYAG