Sex: U
Vaccine: FLU4, VARZOS
Symptoms: Blister, Culture throat positive, Herpes zoster, Influenza, Influenza B virus test positive
Clinical narrative: mild breakthrough after shingles shots, diagnosed as shingles/suspected vaccination failure; mild breakthrough after flu shot, a nasal swab revealed Influenza B/suspected vaccination failure; shingles; a nasal swab revealed Influenza B.; sniffling; small blister; This case was reported by a consumer via other manufacturer and described the occurrence of suspected vaccination failure in a patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Flu Seasonal QIV Dresden (Influenza vaccine Quadrivalent unspecified season) for prophylaxis.   On an unknown date, the patient received Shingrix and Influenza vaccine Quadrivalent unspecified season. On an unknown date, unknown after receiving Shingrix and not applicable after receiving Influenza vaccine Quadrivalent unspecified season, the patient experienced vaccination failure (serious criteria GSK medically significant), vaccination failure (serious criteria GSK medically significant), shingles, influenza b virus infection, sniffles and blister. On an unknown date, the outcome of the vaccination failure, vaccination failure, shingles, influenza b virus infection, sniffles and blister were unknown.   It was unknown if the reporter considered the vaccination failure, shingles, influenza b virus infection, sniffles and blister to be related to Shingrix. It was unknown if the reporter considered the vaccination failure, shingles, influenza b virus infection, sniffles and blister to be related to Influenza vaccine Quadrivalent unspecified season.  Additional details were provided as follows: The case was reported by the patient. The age at vaccination was not reported. It was unknown if the patient had any medical history, concomitant disease or risk factor. The patient's medical treatment(s), past vaccination(s), concomitant medications and family history were not provided. The patient received a dose of Influenza vaccine produced by unknown manufacturer (lot number and expiry date were not reported) and Shingrix via unknown route in unknown administration site for prophylactic vaccination. The patient developed a non-serious influenza B (influenza), sniffling (rhinorrhoea), shingles (herpes zoster) and one small blister (blister) (unknown latency) following the administration of Influenza vaccine. The patient reported he/she had very mild breakthrough after Flu and Shingles shots. In both cases he/she had no symptoms.  The patient was sniffling and thought it was allergy until a nasopharyngeal swab (culture throat) was done and revealed Influenza B.  A routine visit to the dermatologist revealed one small blister which was diagnosed as shingles. The patient was thankful that he/she got the shots. It was unknown if the patient experienced any additional symptoms/events. It was not reported if the patient received any corrective treatment for the events. The reporter did not report causality of events with suspect. At time of reporting, the outcome of events was unknown. There would be information available on the batch number for this case. This case was considered as suspected vaccination failure as details regarding time to onset for influenza B and time to onset and laboratory test confirming shingles were unknown at the time of reporting.