Age: 83.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Dyspnoea, Feeling abnormal, Gait disturbance
Clinical narrative: still had shortness of breath/ can't get a deep breath/the breathing got worse/ had breathing problems when she had movement, like bending down to pick up something on the floor or walking up/down; can't walk very far; tested positive for COVID a month ago (asymptomatic); This spontaneous case was reported by a patient and describes the occurrence of ASYMPTOMATIC COVID-19 (tested positive for COVID a month ago (asymptomatic)), DYSPNOEA EXERTIONAL (still had shortness of breath/ can't get a deep breath/the breathing got worse/ had breathing problems when she had movement, like bending down to pick up something on the floor or walking up/down) and GAIT DISTURBANCE (can't walk very far) in an 83-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 0460214, 010M20A and 012?204) for COVID-19 vaccination.     The patient's history of allergies was reported as none. Patient did not receive other vaccines 1 month prior to Moderna COVID-19 Vaccine.    On 22-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 19-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 01-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 02-May-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In August 2022, the patient experienced ASYMPTOMATIC COVID-19 (tested positive for COVID a month ago (asymptomatic)). On an unknown date, the patient experienced DYSPNOEA EXERTIONAL (still had shortness of breath/ can't get a deep breath/the breathing got worse/ had breathing problems when she had movement, like bending down to pick up something on the floor or walking up/down) and GAIT DISTURBANCE (can't walk very far). At the time of the report, ASYMPTOMATIC COVID-19 (tested positive for COVID a month ago (asymptomatic)) had resolved, DYSPNOEA EXERTIONAL (still had shortness of breath/ can't get a deep breath/the breathing got worse/ had breathing problems when she had movement, like bending down to pick up something on the floor or walking up/down) had not resolved and GAIT DISTURBANCE (can't walk very far) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In August 2022, SARS-CoV-2 test: (Positive) tested positive a month ago (asymptomatic). On an unknown date, Blood test: Normal. On an unknown date, Chest X-ray: Normal. On an unknown date, Computerised tomogram: Normal. On an unknown date, Exercise electrocardiogram: Normal. On an unknown date, Pulmonary function test: Normal. On an unknown date, SARS-CoV-2 test: (Negative) tested negative 5 days and 7 days later..         Concomitant medications were not reported by the reporter.  After the second booster, the breathing got worse but not to the point of gasping. Last week, it got worse. She had no breathing problems when she was sitting or lying down, but she does when she had movement, like bending down to pick up something on the floor or walking up/down stairs. Patient stated that she saw every doctor - pulmonologist, heart, bone marrow. She saw a series of doctors and had numerous tests including 2 pulmonary breathing tests, and other tests all came back normal.   Treatment details was not reported by the reporter.  Company comment: This is a spontaneous case regarding a 83-year-old female patient, with no reported medical history, who received 4 doses of mRNA-1273 vaccine and experienced non serious event of Dyspnoea exertional. The patient reported that she received first dose on Friday and on Monday morning she was gasping for breath going up the stairs. It did not happen after the second dose or the first booster, but she still had shortness of breath, she could not walk very far. After the second booster, the breathing got worse but not to the point of gasping. She's had no breathing problems when she is sitting or lying down, but she does when she has movement, like bending down to pick up something on the floor or walking up/down stairs. Patient states she's seen a series of doctors and had numerous tests including treadmill tests, chest X-rays, CTs, blood tests, 2 pulmonary breathing tests, among others tests and all came back normal. In addition, patient experienced non serious event of Asymptomatic COVID-19 (AESI) approximately 3 months after receiving fourth dose. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-642864 (Patient Link).; Sender's Comments: This is a spontaneous case regarding a 83-year-old female patient, with no reported medical history, who received 4 doses of mRNA-1273 vaccine and experienced non serious event of Dyspnoea exertional. The patient reported that she received first dose on Friday and on Monday morning she was gasping for breath going up the stairs. It did not happen after the second dose or the first booster, but she still had shortness of breath, she could not walk very far. After the second booster, the breathing got worse but not to the point of gasping. She's had no breathing problems when she is sitting or lying down, but she does when she has movement, like bending down to pick up something on the floor or walking up/down stairs. Patient states she's seen a series of doctors and had numerous tests including treadmill tests, chest X-rays, CTs, blood tests, 2 pulmonary breathing tests, among others tests and all came back normal. In addition, patient experienced non serious event of Asymptomatic COVID-19 (AESI) approximately 3 months after receiving fourth dose. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.