Sex: F
Vaccine: COVID19
Symptoms: Neuropathy peripheral, Oesophageal pain, Pain in extremity, Paraesthesia, Trigeminal nerve disorder
Clinical narrative: On her arms, from mid forearm to fingertips had kind of neuropathy feeling; the right side of her face had tingling nerve/feet up to mid-calf had tingling; entire chest felt like it was on fire, which went up the neck; entire chest felt like it was on fire, which went up the neck/aching in the neck; Later added that it was more than esophageal, digestive burning; sore arm; legs felt wobbly like they could give out from under her, but they didn't.; digestive burning; trigeminal nerve thing; Ocular migraine; vision gets flashing lights; This is a spontaneous report from a non-contactable other hcp (patient herself).   A 61-years-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE, Formulation: Solution for injection), dose 1 via an unspecified route of administration, administered in Arm Right on an unspecified date (Batch/Lot number was not reported) as single dose for COVID-19 immunisation. Medical history included allergies to medicines like CT dyes, but it's always been tightness in the chest, a little shortness of breath. The patient's concomitant medications were not reported. Reports that she had an odd reaction to her first vaccine. Her entire chest felt like it was on fire, which went up the neck. A lot of allergies to medicines like CT dyes, but it's always been tightness in the chest, a little shortness of breath. This was different. Describes it as you could draw a circle on her chest. the whole chest felt like it was on fire. Later added that it was more than esophageal, digestive burning. Started about 5 hours after vaccine administered. She wants to know if there are other people with that, and if so, should she get the second dose. Says symptoms persisted for about 72 hours after, had aching in the neck, the original burning in cavity of chest quit, but still had one spot on the right side of chest and neck. 10:15 am tuesday got shot, by saturday, like someone flipped a light switch, and everything that was going on just quit. Says she has weird things with medicine. Caller then asked about myocarditis. Knows most of those were younger boys. Do you ever get older people? And would it resolve on it's own and would it resolve on it's own without steroids? Did they take the second vaccine and were they ok? Or did they have to take medications for that? Were they all men? She says the other thing that happened is that the morning after the vaccination, her legs (no history of neuropathy) feet up to mid-calf had tingling, not burning, and legs felt wobbly like they could give out from under her, but they didn't. She was able to keep walking. On her arms, from mid forearm to fingertips had kind of neuropathy feeling. No signs of stroke. Says she doesn't want to end up with MS or a heart problem. On the day of vaccine, the right side of her face had tingling nerve, like you could draw a line from temple to nose on the cheekbone. Was tingly several times, but didn't stay. States it was almost like a trigeminal nerve thing, or like an ocular migraine, and that part of your vision gets flashing lights, and there is a little brown haze and squiggly lines. This happened on her right side (also side of injection). Did the Bells Palsy resolve itself or did it result in the paralysis of the face? What about Guillain Barre? Says it is probably too soon to know if anyone has gotten MS but wondering about GBS. What happens when you put second dose in there, more permanent, does that mean you have to have a history of GBS? Or can you get GBS from the vaccine? Due for 2nd dose 17AUG. How much protection does she have with one dose and should she get the second dose. The outcome of the events was recovered on an unspecified date in 2021.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Based on the information in the case report and a plausible temporal relationship,  a possible causal relationship between the event Peripheral neuropathy and suspect drug BNT162B2 cannot be excluded.   The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.