Age: 49.0
Sex: F
Vaccine: COVID19
Symptoms: Antibody test, Coronary artery dissection, Myocardial infarction
Clinical narrative: Twelve hours after receiving the dose she had a heart attack; underwent a Spontaneous Coronary Artery Dissection; This spontaneous case was reported by a consumer and describes the occurrence of MYOCARDIAL INFARCTION (Twelve hours after receiving the dose she had a heart attack) and CORONARY ARTERY DISSECTION (underwent a Spontaneous Coronary Artery Dissection) in a 49-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 025B21A) for COVID-19 vaccination.     No Medical History information was reported.    On 14-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In April 2021, the patient experienced MYOCARDIAL INFARCTION (Twelve hours after receiving the dose she had a heart attack) (seriousness criterion medically significant) and CORONARY ARTERY DISSECTION (underwent a Spontaneous Coronary Artery Dissection) (seriousness criterion medically significant). At the time of the report, MYOCARDIAL INFARCTION (Twelve hours after receiving the dose she had a heart attack) and CORONARY ARTERY DISSECTION (underwent a Spontaneous Coronary Artery Dissection) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In May 2021, Antibody test: showed very strong antibodies showed very strong antibodies. In September 2021, Antibody test: showed no antibodies showed no antibodies.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       No Concomitant medication was reported.    No treatment medications were reported.  Company comment: This case concerns a 49-year-old female patient, with no reported medical history, who experienced the serious  (medically significant according to list and per medical judgment), unexpected events of myocardial infarction and coronary artery dissection. The events occurred 12 hours after the patient received the first dose of mRNA 1273 COVID-19 vaccine. Patient had antibody tests which showed that after 1 month after the vaccine, her antibodies were very strong but after 5 months, she had no antibodies. The patient did not receive the second dose due to the adverse events. At the time of report, outcome of events were unknown and no treatment information were given. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.; Sender's Comments: This case concerns a 49-year-old female patient, with no reported medical history, who experienced the serious  (medically significant according to IME list and per medical judgment), unexpected events of myocardial infarction and coronary artery dissection. The events occurred 12 hours after the patient received the first dose of mRNA 1273 COVID-19 vaccine. Patient had antibody tests which showed that after 1 month after the vaccine, her antibodies were very strong but after 5 months, she had no antibodies. The patient did not receive the second dose due to the adverse events. At the time of report, outcome of events were unknown and no treatment information were given. The benefit-risk relationship of mRNA 1273 vaccine is not affected by this report.