Sex: U
Vaccine: VARZOS
Symptoms: Nasal crusting, Oral discomfort, Pain, Paraesthesia, Pruritus
Clinical narrative: Thumbnail feel pain as if I burned it cooking; Nail decides to separate from the thumb; Underneath nail bed was puss, oozing, wet; Severely allergic to Neomycin in vaccine; Contact dermatitis showing up in random areas; Broke out all over my body in hives; Hair had thinned; Scalp showed flaking as if dandruff had started; Left foot started to tingle; Left foot started itch; Upper lip is feeling burnt; Red upperlip; Right nostril is chapped crusty; Right nostril is bloody oozing pus inside; Inflammation to the eyelids; Chapped upper lip; Painful upper lip; Red upper eyelid; Crusty eyelid; Underneath nail bed was puss, oozing, wet; This case was reported by a consumer and described the occurrence of chapped lips in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis.   On 2nd November 2021, the patient received the 1st dose of Shingles vaccine. On 6th November 2021, 4 days after receiving Shingles vaccine, the patient experienced chapped lips and lip pain. On 17th November 2021, the patient experienced erythema eyelid and eye crusting. On 15th December 2021, the patient experienced lip redness. In December 2021, the patient experienced inflammation of eyelids, nasal crusting and epistaxis. In January 2022, the patient experienced burning lips. In February 2022, the patient experienced hair thinning, flaking scalp, tingling of extremity and localized itching. In March 2022, the patient experienced hives. On an unknown date, the patient experienced nail disorder, purulent discharge, nail bed disorder, pain burning, drug allergy and contact dermatitis. On an unknown date, the outcome of the chapped lips, lip pain, erythema eyelid, eye crusting, lip redness, inflammation of eyelids, nasal crusting, epistaxis, purulent discharge and nail bed disorder were recovered/resolved and the outcome of the nail disorder, burning lips, pain burning, hair thinning, flaking scalp, localized itching, hives, drug allergy and contact dermatitis were unknown and the outcome of the tingling of extremity was not recovered/not resolved.   It was unknown if the reporter considered the chapped lips, lip pain, erythema eyelid, eye crusting, lip redness, inflammation of eyelids, nasal crusting, epistaxis, nail disorder, purulent discharge, nail bed disorder, burning lips, pain burning, hair thinning, flaking scalp, tingling of extremity, localized itching, hives, drug allergy and contact dermatitis to be related to Shingles vaccine.     Additional Information: GSK Receipt Date: 14-APR-2022 Reporter's comment: The patient self-reported the case. The patient received first dose of Shingles vaccine and had a chapped painful upper lip lasting 16 days. By 17th November 2021, the patient had red crusty upper eyelids lasting 3 days. On 15th December 2021 upper lip had become chapped and red and painful lasting again more than a week. Then returned the inflammation to the eye lids again, lasting 3 days.  In mid-December 2021, the patient's right nostril was chapped crusty bloody oozing puss inside lasting through Christmas. Beginning of January 3 or 4 (unspecified date), the patient's upper lip was feeling burnt chapped and painful.  The patient reported that, thumbnail on right hand started to feel pain as if burned it cooking but after one week of pain the nail decided to separate from the thumb.  The patient reported that, he/she happened to work for an ophthalmologist and used a very high-powered microscope he/she could see underneath the nail bed was puss and oozing and wet.  This did not heal for over four weeks the patient noticed by early February 2022 a lot of hair had thinned out and scalp was started to show flaking as if dandruff had started. The patient mentioned no scalp pain. In mid-February 2022, the patient's upper lip was once again chapped and burned and painful lasting 7-10 days. The patient reported that, his/her left foot started to tingle and itch, still tingles till the reporting time. The patient reported that, March 2022 was quiet until the end and patient broke out all over body in hives. (never had hives before). Back in January he/she saw an optometrist he said patient was perhaps allergic to the Neomycin in Shingles vaccine and it was trying to came out in the form of contact dermatitis showing up in random areas. The patient also saw a dermatologist and she advised to not get the 2nd dose, as patient was severely allergic. The reporter asked how long did it take for this horrible vaccine to leave his/her once perfectly healthy normal body. The patient wanted to feel like normal again.  The patient asked to get this horrible monster off shelves. The reporter asked for help to feel whole again and the patient only received Shingles vaccine in his/her life.  The patient work in ophthalmology and he/she saw shingles occasionally in the cornea.