Age: 65.0
Sex: F
Vaccine: COVID19
Symptoms: Rash, Ultrasound scan
Clinical narrative: All of a sudden started to feel lots of pain in my chest; Heart was really raising; Blood pressure felt high; Rash all over my neck and chest; This spontaneous case was reported by a patient (subsequently medically confirmed) and describes the occurrence of CHEST PAIN (All of a sudden started to feel lots of pain in my chest), PALPITATIONS (Heart was really raising) and HYPERTENSION (Blood pressure felt high) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 047A21A and 014M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included No adverse event (No medical history reported).   On 27-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 28-Mar-2021, the patient experienced CHEST PAIN (All of a sudden started to feel lots of pain in my chest) (seriousness criterion hospitalization), PALPITATIONS (Heart was really raising) (seriousness criterion hospitalization) and HYPERTENSION (Blood pressure felt high) (seriousness criterion hospitalization). On 29-Mar-2021, the patient experienced RASH (Rash all over my neck and chest). The patient was hospitalized from 28-Mar-2021 to 29-Mar-2021 due to CHEST PAIN, HYPERTENSION and PALPITATIONS. On 29-Mar-2021, CHEST PAIN (All of a sudden started to feel lots of pain in my chest), PALPITATIONS (Heart was really raising) and HYPERTENSION (Blood pressure felt high) had resolved. At the time of the report, RASH (Rash all over my neck and chest) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 28-Mar-2021, Catheterisation cardiac: unknown (Inconclusive) unknown. On 28-Mar-2021, Echocardiogram: unknown (Inconclusive) unknown. On 28-Mar-2021, Ultrasound scan: unknown (Inconclusive) unknown.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Treatment medication included nitroglycerin given twice.  Action taken with mRNA-1273 in response to the events was not applicable.  On next day after second dose, while watching movie the patient had all of a sudden started to have lots of pain on her chest (never had this before), then her heart was really raising, and blood pressure felt high. This lasted for about seven hours. Patient went to hospital because patient thought was having a heart attack. Patient was given nitroglycerin which helped within a few minutes. Then they gave her another nitroglycerin and pain went down and was feeling no more pain. However, subject was admitted to the hospital and they did lots of test with one of them was a cardiac catherization, also echocardiogram and sonogram. Patient indicated her heart was fine, no heart attack, never experienced anything like that, and that next day, she had a rash all over my neck and chest.  Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Further information has been requested   This case was linked to MOD-2021-073606 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Further information has been requested