Age: 77.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Asthenia, Chills, Fatigue, Feeling abnormal
Clinical narrative: her legs feel swollen but do not look swollen; UPPER LEG/KNEE PAIN/sore shoulder joints; Chills; 18 hours after the first dose around 3 am she woke up and could not get out of bed due to muscle pains; fatigue; Muscles were in pain and weak; could not lift legs/could not bend to toes/when she moves it is hard to bend and; flu-like feeling; Body is stiff; "I feel like I cannot function"; This spontaneous case was reported by a consumer and describes the occurrence of ASTHENIA (Muscles were in pain and weak), LIMB DISCOMFORT (could not lift legs/could not bend to toes/when she moves it is hard to bend and), INFLUENZA LIKE ILLNESS (flu-like feeling), MUSCULOSKELETAL STIFFNESS (Body is stiff) and HYPOKINESIA ("I feel like I cannot function") in a 77-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 046B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hashimoto's thyroiditis since 01-Oct-2014, Hypothyroidism since 19-Aug-2008, High cholesterol since 11-May-1991 and Glaucoma since 18-Nov-2009. Concomitant products included ATORVASTATIN from 29-Apr-2018 to an unknown date for High cholesterol, VITAMINS NOS, THYROID, LEVOTHYROXINE SODIUM (LEVOTHYROXIN) from 19-Aug-2008 to an unknown date, TIMOLOL MALEATE (TIMOLOL [TIMOLOL MALEATE]) from 18-Nov-2009 to an unknown date, ACETYLSALICYLIC ACID (ASPIRIN 81) from 29-Apr-2018 to an unknown date and LATANOPROST from 18-Nov-2009 to an unknown date for an unknown indication.    On 20-Apr-2021 at 9:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 21-Apr-2021, the patient experienced ASTHENIA (Muscles were in pain and weak), LIMB DISCOMFORT (could not lift legs/could not bend to toes/when she moves it is hard to bend and), INFLUENZA LIKE ILLNESS (flu-like feeling), MUSCULOSKELETAL STIFFNESS (Body is stiff), HYPOKINESIA ("I feel like I cannot function"), CHILLS (Chills), MYALGIA (18 hours after the first dose around 3 am she woke up and could not get out of bed due to muscle pains) and FATIGUE (fatigue). On 21-Apr-2021 at 3:00 AM, the patient experienced ARTHRALGIA (UPPER LEG/KNEE PAIN/sore shoulder joints). On an unknown date, the patient experienced FEELING ABNORMAL (her legs feel swollen but do not look swollen). The patient was treated with PREDNISONE for Adverse event, at a dose of 40 milligram for 7 days and PARACETAMOL (TYLENOL) for Adverse event, at an unspecified dose and frequency. At the time of the report, ASTHENIA (Muscles were in pain and weak), LIMB DISCOMFORT (could not lift legs/could not bend to toes/when she moves it is hard to bend and), INFLUENZA LIKE ILLNESS (flu-like feeling), MUSCULOSKELETAL STIFFNESS (Body is stiff), HYPOKINESIA ("I feel like I cannot function"), FEELING ABNORMAL (her legs feel swollen but do not look swollen), ARTHRALGIA (UPPER LEG/KNEE PAIN/sore shoulder joints), CHILLS (Chills), MYALGIA (18 hours after the first dose around 3 am she woke up and could not get out of bed due to muscle pains) and FATIGUE (fatigue) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, X-ray: normal (normal) X-raying my hips to see if leg pain is radiating from hips..     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   It was reported that the patient would go for surgery.  Other concomitant medication included statin low dose 10 milligram.  The patient reported that she Stopped taking statin (10 mg. Atorvastatin) for 2-1/2 weeks as side effect is muscle pains.  Result:  No change. All symptoms continued.   A trial prescription for 40 mg. of Prednisone for 7 days (May 14-20, 2021).  Result:  Took away pains immediately but doctor referred me to a rheumatologist to get a diagnosis before continuing this Rx, which has many negative side effects.   She is currently  on another 28-day prescription for Prednisone to give me some relief (8/28/21 to 9/24/21, 1 week each of 20 mg, 10 mg, 5 mg, 2-1/2 mg).    Most recent FOLLOW-UP information incorporated above includes: On 07-Sep-2021: Follow-up contains race, medical History, additional concomitant drugs, event outcome updated, additional events added.