Age: 58.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Body temperature, Joint range of motion decreased, Joint swelling, Malaise
Clinical narrative: Middle finger on right hand was swollen could not make a fist; Middle finger on right hand was swollen could not make a fist; Left wrist was swollen and painful; Left wrist was swollen and painful; Feeling ill; Fever; This spontaneous case was reported by a consumer and describes the occurrence of PERIPHERAL SWELLING (Middle finger on right hand was swollen could not make a fist), JOINT RANGE OF MOTION DECREASED (Middle finger on right hand was swollen could not make a fist), JOINT SWELLING (Left wrist was swollen and painful), MALAISE (Feeling ill) and PYREXIA (Fever) in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product UPADACITINIB (RINVOQ) for Rheumatoid arthritis.    Concurrent medical conditions included Rheumatoid arthritis.   On 01-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 18-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient started UPADACITINIB (RINVOQ) (Oral) 1 dosage form. In 2021, the patient experienced MALAISE (Feeling ill) and PYREXIA (Fever). On an unknown date, the patient experienced PERIPHERAL SWELLING (Middle finger on right hand was swollen could not make a fist), JOINT RANGE OF MOTION DECREASED (Middle finger on right hand was swollen could not make a fist), JOINT SWELLING (Left wrist was swollen and painful) and ARTHRALGIA (Left wrist was swollen and painful). The patient was treated with HYDROCORTISONE (CORTIZONE [HYDROCORTISONE]) at an unspecified dose and frequency. At the time of the report, PERIPHERAL SWELLING (Middle finger on right hand was swollen could not make a fist) had not resolved, JOINT RANGE OF MOTION DECREASED (Middle finger on right hand was swollen could not make a fist) and JOINT SWELLING (Left wrist was swollen and painful) outcome was unknown, MALAISE (Feeling ill) and PYREXIA (Fever) had resolved and ARTHRALGIA (Left wrist was swollen and painful) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Body temperature: Fever of 100.4.         No concomitant medication was reported.  The patient's middle finger on right hand was swollen and cannot made a fist. Cortisone was ineffective. Patient's left wrist was swollen and painful and responded to cortisone shots. Patient was feeling ill and having a fever of 100.4 after having COVID booster shot and stayed in bed for two days.  It was unknown if patient was enrolled in a COVID-19 vaccine trial.  The patient was treated with Cortisone.   The reporter's causality for the events of middle finger on right hand was swollen could not make a fist, left wrist was swollen and painful, fever and feeling ill was not provided for RINVOQ (upadacitinib).  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.