Age: 50.0
Sex: M
Vaccine: COVID19
Symptoms: Limb injury, Thrombosis
Clinical narrative: One month later they found 1 clot in the left wrist and 4 clots in the left leg.; work related injury to his left leg; doctor found a clot in his left leg; This spontaneous case was reported by a consumer and describes the occurrence of THROMBOSIS (doctor found a clot in his left leg) and THROMBOSIS (One month later they found 1 clot in the left wrist and 4 clots in the left leg.) in a 50-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 042J21A, 059E21A and 009D21A) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     Patient was totally healthy prior to vaccination. Patient was not on any medications prior or during vaccination. Patient did not receive any other vaccines within 4 weeks of all 3 doses.    On 10-Jul-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 09-Aug-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 08-Feb-2022, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In October 2022, the patient experienced THROMBOSIS (doctor found a clot in his left leg) (seriousness criterion medically significant) and LIMB INJURY (work related injury to his left leg). In November 2022, the patient experienced THROMBOSIS (One month later they found 1 clot in the left wrist and 4 clots in the left leg.) (seriousness criterion medically significant). At the time of the report, THROMBOSIS (doctor found a clot in his left leg), THROMBOSIS (One month later they found 1 clot in the left wrist and 4 clots in the left leg.) and LIMB INJURY (work related injury to his left leg) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered THROMBOSIS (doctor found a clot in his left leg) and THROMBOSIS (One month later they found 1 clot in the left wrist and 4 clots in the left leg.) to be related. No further causality assessment was provided for LIMB INJURY (work related injury to his left leg).    No concomitant medications were reported. It was reported that patient was totally healthy prior to vaccination. Patient had a work related injury to his left leg, went to the doctor, and they found a clot in his left leg. One month later, they found 1 clot in the left wrist and 4 clots in the left leg. Patient stated that the doctor told the clots may have been because of the vaccine. Patient reported that within 4 weeks of all 3 doses did not have any other vaccines and was not on any medications prior or during vaccination. No treatment medications were reported.  Company comment: This is a spontaneous case reported by a consumer regarding a 50-year-old male patient, with no medical history, who received 3 doses of mRNA-1273 vaccine and experienced unexpected and medically significant events of thrombosis (AESI) after receiving the third dose. According to the report, approximately 8 months after last vaccination, patient had a work related injury to his left leg, he went to the doctor and a clot in his left leg was found. One month later, 1 clot in the left wrist and 4 clots in the left leg were found. Doctor told him that the clots may have been because of the vaccine. At the time of the report, the outcome was unknown. No further details regarding clinical course, diagnostic tests or treatment performed were disclosed. The work related injury to his left leg and the clot found in his left leg could be mutually connected. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.