Sex: F
Vaccine: COVID19, FLUX, VARZOS
Symptoms: Arthralgia, Joint swelling, Magnetic resonance imaging, Pain in extremity, Peripheral swelling
Clinical narrative: clot; swelling and pain in foot / foot was swollen/swelling and pain in calf; swelling and pain in Ankle/ Ankle was swollen; pain in foot, calf and anckle / foot was sore; pain in foot, calf and anckle / foot was sore; This case was reported by a consumer via other and described the occurrence of clot blood in a female patient who received Herpes zoster (Shingles vaccine) for prophylaxis.   Co-suspect products included Flu Seasonal QIV Dresden (Influenza vaccine Quadrivalent unspecified season) for prophylaxis and COVID 19 VACCINE for prophylaxis.   Concomitant products included COVID 19 VACCINE.   In November 2020, the patient received Shingles vaccine. On an unknown date, the patient received Influenza vaccine Quadrivalent unspecified season. On 2nd February 2021, the patient received the 2nd dose of COVID 19 VACCINE. On 15th February 2021, between 2 and 4 months after receiving Shingles vaccine and less than 2 years after receiving Influenza vaccine Quadrivalent unspecified season, the patient experienced clot blood (serious criteria GSK medically significant). In February 2021, the patient experienced swelling of feet, ankle swelling, foot pain and pain ankle. The patient was treated with rivaroxaban (Xarelto). On an unknown date, the outcome of the clot blood was unknown and the outcome of the swelling of feet, ankle swelling, foot pain and pain ankle were recovering/resolving.   It was unknown if the reporter considered the clot blood, swelling of feet, ankle swelling, foot pain and pain ankle to be related to Shingles vaccine and Influenza vaccine Quadrivalent unspecified season.  Additional details were provided as follows: The reporter was the patient's son. The age at vaccination was not reported. The patient did not have medical history and family history. The patient got the Flu vaccine every year. The patient received 2nd dose of Covid vaccine in left arm. The reporter did not have NDC, lot and expiry date for the patient's 1st and 2nd Covid vaccine. The patient was told by the nurse administering the Covid vaccine that the 2nd dose would be a little bit stronger. Either on 04th February 2021 or 05th February 2021, less than a week after receiving Covid vaccine, less than 4 months after receiving Shingles vaccine and less than 2 years after receiving Flu vaccine, the patient experienced severe swelling and pain in foot, ankle and calf. The patient first noticed left foot was swollen. The patient stated her foot was sore. The reporter did not know if it went to her ankle and then from there. Doctor advised the patient the patient had a clot and was put on Xarelto. An angiography and catheter were suggested to see if she had something closing in her. The patient would be going back in few weeks to see about the clot. The patient had never had this clotting concern before. Reporter clarified that, the patient was going to have another procedure such as angiography or catheter, but the patient had an MRI on 15th February 2021, 13 days after receiving Covid vaccine, and was diagnosed with the clot. The patient spoke with doctor who decided to put the patient on Xarelto. No information of NDC, lot and expiry date or dosing of Xarelto was provided. The reporter thought the patient's clot was weird and odd. At the time of reporting, the pain and swelling were gotten better. No further details were provided. The reporter consented to follow up. It was unknown if the reporter considered the clot blood, swelling of feet, ankle swelling, foot pain and pain ankle to be related to Covid vaccine.