Age: 17.0
Sex: F
Vaccine: MENB
Symptoms: Malaise, Meningitis chemical, Meningitis viral, Nausea, Neck pain
Clinical narrative: viral meningitis; Chemical meningitis; headache; nausea; Malaise; Fatigue/exhausted; Fever; dizziness; sore throat; sore arm; Back ache; neck pain/pain above her cervical spine; This case was reported by a physician via sales rep and described the occurrence of viral meningitis in a 17-year-old female patient who received Men B NVS (Bexsero) (batch number ABX795AA, expiry date May 2020) for prophylaxis.   On 15th July 2019, the patient received the 1st dose of Bexsero .5 ml. In July 2019, less than a week after receiving Bexsero, the patient experienced nausea (serious criteria hospitalization), malaise (serious criteria hospitalization), fatigue (serious criteria hospitalization), fever (serious criteria hospitalization), dizziness (serious criteria hospitalization), sore throat (serious criteria hospitalization), pain in arm (serious criteria hospitalization), back pain (serious criteria hospitalization) and neck pain (serious criteria hospitalization). On 16th July 2019, the patient experienced viral meningitis (serious criteria hospitalization and GSK medically significant), meningitis chemical (serious criteria hospitalization and GSK medically significant) and headache (serious criteria hospitalization). The patient was treated with ibuprofen (Motrin), paracetamol (Tylenol) and ceftriaxone. On an unknown date, the outcome of the viral meningitis, meningitis chemical, headache, nausea, malaise, fever, dizziness, sore throat, pain in arm, back pain and neck pain were unknown and the outcome of the fatigue was not recovered/not resolved.   The reporter considered the viral meningitis, meningitis chemical, headache, nausea, malaise, fatigue, fever, dizziness, sore throat, pain in arm, back pain and neck pain to be related to Bexsero.  Additional details were provided as follows: The patient had not received any other vaccines on the day which received Bexsero and was not sick going in. It was reported that 24 hours after receiving Bexsero, the patient experienced worst headache she ever had.  The patient also experienced nausea (no vomiting), malaise, fatigue, temperature was 101, dizziness, sore throat, sore arm, back ache, neck pain, but she could move her neck around. The patient also had pain above her cervical spine. The patient underwent a strep test and culture that was found to be negative.  The patient received Tylenol, Motrin, fluids and was told to rest and to call if it would worse. MIT got worse so on 18th July 2019, the patient went to emergency room. The patient was then transferred to the another hospital where they completed blood work and a spinal tap and received Ceftriaxone in case it was bacterial The patient spent 2 days in the hospital. The patient also underwent bacterial meningitis culture and it was found to be negative. The patient was also tested for Lyme disease and it was not Lyme. The patient was also tested for herpes culture and it came out to be negative. The doctor concluded it must have been a virus or viral meningitis because everything else was ruled out. The doctor knew anyone could not get a virus from an inactive vaccine and wondered if it could be chemical meningitis caused by the vaccine and wanted to know if there was any reports like this. The patient's mother was very passionate about her getting the vaccine because they knew someone who had meningitis before.  The physician wondered if they should administer the patient 2nd dose of Bexsero. The patient was referred to the medical information. The doctor kept the patient in touch with the medical scientist. At the time of reporting, the patient was at home, doing okay but was exhausted. Doctor asked to see her for a follow up, but the patient's mother wanted to wait a few days because they just returned from hospital and were exhausted. The physician wanted to report the adverse event, even though the emergency room doctor also submitted a VAERS report. The reporter hoped if someone could follow up with the physician. She stated it could be a coincidence or might be the patient had something brewing already or was exposed in the waiting room, but also concerned it was caused by the vaccine. The fullform of MIT was requested to the reporter but could not receive the reply.      Lab Comments: on an unknown date in July 2019, the patient was tested negative for lyme disease