chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 41.0
Sex: F
Vaccine: FLU3
Symptoms: Anxiety, Asthenia, Coordination abnormal, Encephalitis, Guillain-Barre syndrome
Clinical narrative: Pt is having progressive numbness and weakness of left side of body including her tongue. Pt has been sent to neurologist. There is concern the pt may have Guillain Barre. Pt is in the process of treatment. FU on 12/3 from MD states pt is somewhat anxious and has some give away weakness in her legs as well as astasia abasia when walking. Will start her on steriods and ask her to come back in after getting test results. Diagnosed with acute disseminated encephalomyelitis
Age: 41.0
Sex: F
Vaccine: FLU3
Symptoms: Muscular weakness, Paraesthesia
Clinical narrative: Pt is having progressive numbness and weakness of left side of body including her tongue. Pt has been sent to neurologist. There is concern the pt may have Guillain Barre. Pt is in the process of treatment. FU on 12/3 from MD states pt is somewhat anxious and has some give away weakness in her legs as well as astasia abasia when walking. Will start her on steriods and ask her to come back in after getting test results. Diagnosed with acute disseminated encephalomyelitis
Age: 55.0
Sex: M
Vaccine: FLU3
Symptoms: Neuralgia
Clinical narrative: Nerve pain associated with area where flut shot given. Sharp, prickly pain when use arm when lifting. Pain lasted for about 3 weeks. Took ibuprofen 600 mg intermittently.
Age: 50.0
Sex: F
Vaccine: FLU3
Symptoms: Dizziness, Injection site erythema, Injection site swelling, Injection site warmth, Pruritus
Clinical narrative: Redness at site with edema and warm to touch X 2-3 days. Dizziness for 10 minutes, post vax. Rash at site X 3 days with itching. Complete recovery.
Age: 50.0
Sex: F
Vaccine: FLU3
Symptoms: Rash
Clinical narrative: Redness at site with edema and warm to touch X 2-3 days. Dizziness for 10 minutes, post vax. Rash at site X 3 days with itching. Complete recovery.
Age: 39.0
Sex: F
Vaccine: FLU3
Symptoms: Pain
Clinical narrative: Vaccine administered into top of arm at shoulder location. Extreme pain radiating into and down the arm. Doctor said it possibly hit the bone and/or nerve. Improperly given.
Age: 81.0
Sex: F
Vaccine: FLU3
Symptoms: Oedema, Pain
Clinical narrative: States day after immunization arm very sore and swollen. remains painful, teking Tylenol every two time a day. Talked to nurse at MD's office. Told to use warm compresses. Pain (2 weeks later) from site of immunization to elbow.
Age: 23.0
Sex: M
Vaccine: FLU3
Symptoms: Asthenia, Hyperhidrosis, Pallor, Tremor, Visual disturbance
Clinical narrative: 10 minutes, post vax, the pt reported vision changes, weakness, shakiness but was coherent and oriented. He then became diaphoretic, pale and required assistance from local EMT's. He was transported to the local hospital and given fluids. He recovered.
Age: 39.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Chills, Injection site erythema, Injection site pain, Injection site swelling, Lymphadenopathy
Clinical narrative: Pt developed pain at the injection site. It was raised, red with chills and glands swollen X 5 days. Resolved now.
Age: 69.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site hypersensitivity, Myalgia, Vasodilation procedure
Clinical narrative: Second arm felt sore Sunday. Six days later pt states felt tightness around muscle. Pt describes light red circle around muscle 10 day later. Pt also states pain extended down arm and into back and neck. Pt states will see private MD on 11/17/2001 for evaluation. Red circle nickel size around injection site today. Pt took 5 days of Amoxicillin.
Age: 1.2
Sex: F
Vaccine: MMR, PNC
Symptoms: Rash
Clinical narrative: The pt developed small, red dots all over her trunk and face. No fever. This lasted 3 days. No treatment.
Age: 1.6
Sex: F
Vaccine: DTAP, HBHEPB, PNC
Symptoms: Cellulitis, Injection site reaction, Pyrexia
Clinical narrative: Pt developed increased temperature of 102F; local cellulitis approx. 2" X 2". Treated with ceftriaxone 600mg X 2 and given Augmentin X 8 days.
Age: 1.25
Sex: U
Vaccine: DTAP, HIBV, PNC, VARCEL
Symptoms: Febrile convulsion, Pyrexia
Clinical narrative: Fever 104 13 hours after vaccination. DTaP, Hib, PCV and Varivax. Simple febrile seizure ensued.
Age: 1.25
Sex: M
Vaccine: MMR, PNC
Symptoms: Flushing, Lethargy, Vomiting
Clinical narrative: The 1st reaction was on 8/13/01 with vomiting, red and flushed face, legs and arms and lethargy which lasted 45 minutes. The 2nd reaction was on 11/14/01, post vax of Comvax and Varivax, with lethargy and broke out in hives which lasted over an hour. Gave him 1/4 tsp of Benadryl.
Age: 0.2
Sex: M
Vaccine: DTAP, HBPV, IPV, PNC
Symptoms: Oedema
Clinical narrative: The morning after DTaP, HIB, IPV, Prevnar #1 pt's whole body was swollen per parents. No other symptoms. Resolved next AM. Not seen by MD.
Sex: M
Vaccine: LYME
Symptoms: Cellulitis, Confusional state, Pyrexia, White blood cell count increased
Clinical narrative: Recent problem with cellulitis of leg prior to receiving 2nd Lymerix. Two days after vaccination, developed fever and confusion. Taken to ED, cultured and given IV fluid. Started on antibiotics.
Age: 62.0
Sex: M
Vaccine: LYME
Symptoms: Arthralgia, Chest discomfort, Conjunctivitis, Dry eye, Hyperhidrosis
Clinical narrative: Flu like symptoms, pains hands and feet, blood shot eyes, low grade fever, fatigue, night sweats, joint pain, dry eyes, poor grip. Pressure on chest and throat.
Age: 62.0
Sex: M
Vaccine: LYME
Symptoms: Influenza like illness, Pain, Pyrexia, Sensation of pressure
Clinical narrative: Flu like symptoms, pains hands and feet, blood shot eyes, low grade fever, fatigue, night sweats, joint pain, dry eyes, poor grip. Pressure on chest and throat.
Age: 55.0
Sex: M
Vaccine: PPV
Symptoms: Injection site erythema, Injection site swelling, Rash
Clinical narrative: The pt was given 1 dose of pneumovax 23 valent on 11/26/01. (The pt claims this was the 1st time he had ever received this). On 11/28/01, the pt presents with a swollen, red, enlarged, rash on arm at the injection site.
Age: 0.2
Sex: M
Vaccine: DTAP, HBHEPB, IPV
Symptoms: Irritability, Myoclonus, Pyrexia
Clinical narrative: Mother reports that the pt was very upset, post vax. When he finally settled down and went to sleep, he had some myoclonic jerks. He also had a fever (not measured). Immunizations given on 8/20/01.
Age: 48.0
Sex: F
Vaccine: HEP, HEPA
Symptoms: Lymphadenopathy, Pain
Clinical narrative: Right upper arm muscle hard, painful. Enlarged lymph nodes under right arm and right side of neck. Upper right arm 1 cm larger than left arm. Decreased range of motion in right arm.
Age: 10.0
Sex: F
Vaccine: HEP
Symptoms: Anxiety, Confusional state, Eye movement disorder, Injury, Musculoskeletal stiffness
Clinical narrative: Immediately following vaccination, the pt collapsed to the floor. She was pale, had a slight stiffness to her extremities (right arm), eyes rolled back and hit her face on the side of the desk. She was only "out" for a very few seconds and was talking but appeared dazed. No history of fainting in the past. She had been very apprehensive before the shot was given. Mom was advised to take her to the doctor but it was not done.
Age: 10.0
Sex: F
Vaccine: HEP
Symptoms: Pallor, Syncope
Clinical narrative: Immediately following vaccination, the pt collapsed to the floor. She was pale, had a slight stiffness to her extremities (right arm), eyes rolled back and hit her face on the side of the desk. She was only "out" for a very few seconds and was talking but appeared dazed. No history of fainting in the past. She had been very apprehensive before the shot was given. Mom was advised to take her to the doctor but it was not done.
Age: 13.0
Sex: F
Vaccine: HEP, MMR
Symptoms: Eye swelling, Hypersensitivity, Pruritus, Urticaria
Clinical narrative: On 11/25/01, had puffy and itchy eyes which spread to hives on trunk on 11/27/01. On 11/27/01, was seen by MD and prescribed Cortisone pills, saying reaction to Hep-B shot.
Age: 56.0
Sex: F
Vaccine: PPV
Symptoms: Injection site erythema, Injection site induration, Injection site warmth
Clinical narrative: 3 days post 1st Pneumovax  vaccination local reaction consisting of 11x18cm red, indurated warm area at site of vaccination (L triceps). no fever, chills, etc.
Age: 0.2
Sex: F
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: High-pitched crying
Clinical narrative: Adopted infant with no known hlth problems brought in clinic for 1st immunizations, 1 1/2-2hrs following vaccine child had high pitched cry that lasted for 2-3hrs. No fever or seizure activity, lasted for 2-3 hrs. No fever or seizure activity. Parent had gone thru similar experience w. another adopted child who ???
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site erythema, Injection site hypersensitivity, Injection site induration, Vasodilation procedure
Clinical narrative: Child developed erythema and induration (area measuring greater than 50 mm) at injection site for DTaP. Did not show this to mother until 6 days after injection. Non-tender, warm to touch. No fever, seizures noted.
Age: 2.0
Sex: F
Vaccine: DTAP, IPV
Symptoms: Contusion, Injection site induration
Clinical narrative: Pt had 2 by 3 bruise, 4 by 6 area of induration. Physician's assessment- local reaction to immunization. No treatment.
Age: 1.25
Sex: M
Vaccine: DTAP, MMR
Symptoms: Erythema, Injection site erythema, Injection site swelling, Injection site warmth, Irritability
Clinical narrative: The day after shots, parents noticed redness, swelling and warmth around shots. Seen in office, 2 days after shots with a 4cm area of erythema surrounding injection sites, warm to touch and raised up. This resolved 3 days after shots. Also had a low-grade temperature of 99.5F and irritability, which all resolved.
Age: 1.25
Sex: M
Vaccine: DTAP, MMR
Symptoms: Pyrexia
Clinical narrative: The day after shots, parents noticed redness, swelling and warmth around shots. Seen in office, 2 days after shots with a 4cm area of erythema surrounding injection sites, warm to touch and raised up. This resolved 3 days after shots. Also had a low-grade temperature of 99.5F and irritability, which all resolved.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site erythema, Injection site induration, Injection site reaction, Laboratory test abnormal, Vasodilation procedure
Clinical narrative: MOC called 10:25 AM on 11/29/2001 to report that child had local reaction on left anterior thigh site of DTaP, erythema, warmth, induration "about as wide as a racquetball" (approxiamately 5 cm). No fever. Active/playing. Advised warm compresses, ibuprofen ok (given by MOC).
Age: 4.0
Sex: M
Vaccine: DTAP, HEPA, IPV, MMR
Symptoms: Gait disturbance, Injection site induration, Injection site swelling
Clinical narrative: The pt returned to the office for swelling of left thigh and difficulty walking. On exam, the left leg was swollen from his hip to his knee and firm. He limped with ambulation. No redness or fever. He was treated with Augmentin.
Age: 2.0
Sex: M
Vaccine: HIBV, MMR, VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: Pt developed a mild chickenpox eruption.
Age: 64.0
Sex: M
Vaccine: PPV
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: Pt developed redness, warmth and swelling of left upper extremity to forearm. No temperature. Rx'd Keflex 500mg po qid X 10 days.
Age: 64.0
Sex: M
Vaccine: PPV
Symptoms: Pain, Paraesthesia
Clinical narrative: 7 PM night of injection whole right shoulder was throbbing, shooting tingles down back from shoulder blade, unsteady on feet, took Tylenol with some relief. Next day much better. Still taking Tylenol, still having muscle soreness as of 11/30/2001.
Age: 1.08
Sex: M
Vaccine: DTAP, VARCEL
Symptoms: Injection site erythema, Injection site induration, Injection site warmth
Clinical narrative: Pt developed a local reaction at site which was a red, hot to touch and indurated area on thigh. This began the day after immunizations. It was worse on the 2nd day, then was better.
Age: 1.5
Sex: M
Vaccine: DTAP
Symptoms: Injection site hypersensitivity, Oedema, Vasodilation procedure
Clinical narrative: Pt had swelling and redness 3.5 cm by 3.5 cm around injection site left thigh one day after DTaP dose 4 was administered.
Age: 76.0
Sex: F
Vaccine: PPV
Symptoms: Injection site pain
Clinical narrative: Client experienced pain in left arm with onset 3-4 hours after receiving vaccination. She stated the pain started at the vaccination site and progressed down the arm to the wrist. She describes the pain as "intense". She denies any redness, bruising or swelling. Follow up phone call on 11/28/2001 client states pain is almost gone. She has some pain at injection site when lifting something. Denies any numbness or tingling of extremity.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Feeling cold, Hyperhidrosis, Muscle spasms, Nausea, Pain
Clinical narrative: Immediately upon withdrawal of the needle from her arm, the employee complained of feeling sick and nauseated. The employee became very pale/diaphoretic and cool with episodes of syncope and tachycardia. The employee also complained of severe pain in extremities, related to violent muscle cramping. 50mg of IV Benadryl was given.
Age: 28.0
Sex: F
Vaccine: HEP
Symptoms: Pallor, Syncope, Tachycardia
Clinical narrative: Immediately upon withdrawal of the needle from her arm, the employee complained of feeling sick and nauseated. The employee became very pale/diaphoretic and cool with episodes of syncope and tachycardia. The employee also complained of severe pain in extremities, related to violent muscle cramping. 50mg of IV Benadryl was given.
Age: 4.0
Sex: F
Vaccine: DTAP
Symptoms: Injection site swelling
Clinical narrative: Pt developed moderate swelling at the site of the injection.
Age: 7.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Rash
Clinical narrative: Vaccine failure. Diagnosed with chicken pox 12/03/2001.
Age: 1.0
Sex: M
Vaccine: DTAP, HBHEPB, VARCEL
Symptoms: Pyrexia
Clinical narrative: 3 hours, post vax, the pt had a fever that climbed to 103F-104F despite treatment with both Tylenol and Motrin which lasted about 12 hours.
Age: 4.0
Sex: F
Vaccine: DTAP, IPV, MMR
Symptoms: Injection site hypersensitivity, Vasodilation procedure
Clinical narrative: Right upper thigh skin graft raised warm 4 by 4 cm welt at injection site.
Age: 11.0
Sex: M
Vaccine: HEP
Symptoms: Injection site hypersensitivity, Injection site reaction, Rash, Rash maculo-papular
Clinical narrative: Pt had full body rash, rash was red and raised at site of injection, their was a dime sized blister with a quarter sized area of redness around blister. Treatment: Prednisone for 10 days and Claritin for 10 days. No fever and no itchiness.
Age: 6.0
Sex: M
Vaccine: MMR
Symptoms: Skin ulcer
Clinical narrative: Five to fifteen lesions
Age: 6.0
Sex: F
Vaccine: MMR
Symptoms: Skin ulcer
Clinical narrative: Fifty to seventy-five lesions for 2-3 days.
Age: 1.25
Sex: F
Vaccine: DTAP, HBHEPB
Symptoms: Pyrexia
Clinical narrative: Fever deery first 24 hours ag=fter vaccine. Resolved over next 24 hours (2 doses of Tylenol given).
Age: 1.25
Sex: F
Vaccine: DTAP, HIBV
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: Pt developed redness and swelling (about 2cm X 2cm in diameter) around the site of Hib vaccination during the 1st 24 hours then resolved during the next 24 hours. No pain.
Age: 49.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Cough, Pain, Pharyngitis, Pyrexia
Clinical narrative: Symptoms: 10/26/2001 Woke up with chest pains (all over) with sore throat. No fever, lasted 3 days. Three days later developed coughing, sore throat, hot and cold , T 100, no aches. Took Tylenol Cold OTC for five days, saw MD 11/07/2001.
Age: 49.0
Sex: F
Vaccine: FLU3, FLU3
Symptoms: Chest pain, Cough, Pharyngitis, Pyrexia, Vasodilation procedure
Clinical narrative: Symptoms: 10/26/2001 Woke up with chest pains (all over) with sore throat. No fever, lasted 3 days. Three days later developed coughing, sore throat, hot and cold , T 100, no aches. Took Tylenol Cold OTC for five days, saw MD 11/07/2001.
Sex: F
Vaccine: DTAP, HEP, HIBV, IPV, PNC
Symptoms: Apnoea, Coma
Clinical narrative: On 11/15/01 at 01:00, pt was fed and laid on her back. At 03:00, checked baby and determined that she was not breathing. There was no response and no pulse. Called 911 and CRP was performed. Ambulance came and transported to the hospital.
Age: 0.2
Sex: M
Vaccine: DTAP, HBHEPB, IPV, PNC
Symptoms: Apnoea, Sudden infant death syndrome
Clinical narrative: I was told that the mother placed him in his baby bed around 20:00. About an hour later, when she checked on him, he was not breathing. I was told he died at home. COD as per autopsy report -- SIDS
Age: 2.0
Sex: F
Vaccine: PNC
Symptoms: Vomiting
Clinical narrative: The evening of 11/16/01, the child vomited X 1 and no other symptoms were present. The child died in her sleep that night. Cause of Death as per autopsy report was SIDS with focal epiglotitis.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, HIBV, IPV
Symptoms: Feeling cold, Injury, Musculoskeletal stiffness
Clinical narrative: Possible SIDS. Mother found infant at 06:57 on 5/9/01, lying prone in his crib (stiff and cold). Paramedics responded to 911 call and pronounced the death. No trauma or injury found. Information obtained from Sheriff-Coroner's initial death report. Unable to contact mother. On 8/9/01, dx received from Deputy Coroner of blunt force traumatic injuries of torso.
Age: 19.0
Sex: F
Vaccine: HEP
Symptoms: Aortic valve stenosis, Arteritis, Blood creatine phosphokinase increased, Blood pressure increased, Condition aggravated
Clinical narrative: In March, April and September 1995, a 1st, 2nd and 3rd dose of Engerix-B were given. During the summer of 1995 (not known whether after the 2nd or the 3rd dose), this female pt gradually developed fatigue and malaise and was found to have a newly elevated erythrocyte sedimentation rate (Westergren) of 49mm/h in the absence of back pain or other symptoms of active ankylosing spondylitis from which she suffers since 1991. In 10/95, she developed severe headaches and was found to have blood pressure of 220/110 mmHg. She had never before has had hypertension and her blood pressure in 8/95 had been 116/70 mmHg. After starting Enalapril (Enalapril Maleate), she developed acute renal failure, prompting her admission to the hospital. Her exam was remarkable for hypertension, a left-side abdominal bruit and normal pulses in her extremities. Enalapril was discontinued upon hospital admission. Her renal recovery following emergent aortorenal sephenous vein grafts and pulse methylprednisolone has been reported. In 10/97, 90% stenosis of the right renal artery vein graft was treated successfully with angioplasty. At that time a slight stenosis of the mid portion of the right subclavian artery was noted. An MRI in 8/99 showed no further narrowing of the involved arteries. It is mentioned that the dx of Takayasu's arteritis fits well, as she was a young woman with angiographic abnormalties of the subclavian, celiac, superior mesenteria and renal arteries that are characteristic of Takayasu's. It was also mentioned that it is not possible to determine whether the large artery vasculitis in this pt was caused by the vaccination or simply temporally associated. The number of cases of vasculitis that have been reported following vaccination at least raises the possibility of a causal relationship. The underlying rheumatic diseases of both pts described in this article (ankylosing spondylitis for the present case and polymyalgia rheumation for the 2nd pt) suggests the possibility that the pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 19.0
Sex: F
Vaccine: HEP
Symptoms: Fatigue, Headache, Hypochromic anaemia, Malaise, Proteinuria
Clinical narrative: In March, April and September 1995, a 1st, 2nd and 3rd dose of Engerix-B were given. During the summer of 1995 (not known whether after the 2nd or the 3rd dose), this female pt gradually developed fatigue and malaise and was found to have a newly elevated erythrocyte sedimentation rate (Westergren) of 49mm/h in the absence of back pain or other symptoms of active ankylosing spondylitis from which she suffers since 1991. In 10/95, she developed severe headaches and was found to have blood pressure of 220/110 mmHg. She had never before has had hypertension and her blood pressure in 8/95 had been 116/70 mmHg. After starting Enalapril (Enalapril Maleate), she developed acute renal failure, prompting her admission to the hospital. Her exam was remarkable for hypertension, a left-side abdominal bruit and normal pulses in her extremities. Enalapril was discontinued upon hospital admission. Her renal recovery following emergent aortorenal sephenous vein grafts and pulse methylprednisolone has been reported. In 10/97, 90% stenosis of the right renal artery vein graft was treated successfully with angioplasty. At that time a slight stenosis of the mid portion of the right subclavian artery was noted. An MRI in 8/99 showed no further narrowing of the involved arteries. It is mentioned that the dx of Takayasu's arteritis fits well, as she was a young woman with angiographic abnormalties of the subclavian, celiac, superior mesenteria and renal arteries that are characteristic of Takayasu's. It was also mentioned that it is not possible to determine whether the large artery vasculitis in this pt was caused by the vaccination or simply temporally associated. The number of cases of vasculitis that have been reported following vaccination at least raises the possibility of a causal relationship. The underlying rheumatic diseases of both pts described in this article (ankylosing spondylitis for the present case and polymyalgia rheumation for the 2nd pt) suggests the possibility that the pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 19.0
Sex: F
Vaccine: HEP
Symptoms: Red blood cell sedimentation rate increased, Red blood cells urine, Renal failure acute, Rheumatoid arthritis
Clinical narrative: In March, April and September 1995, a 1st, 2nd and 3rd dose of Engerix-B were given. During the summer of 1995 (not known whether after the 2nd or the 3rd dose), this female pt gradually developed fatigue and malaise and was found to have a newly elevated erythrocyte sedimentation rate (Westergren) of 49mm/h in the absence of back pain or other symptoms of active ankylosing spondylitis from which she suffers since 1991. In 10/95, she developed severe headaches and was found to have blood pressure of 220/110 mmHg. She had never before has had hypertension and her blood pressure in 8/95 had been 116/70 mmHg. After starting Enalapril (Enalapril Maleate), she developed acute renal failure, prompting her admission to the hospital. Her exam was remarkable for hypertension, a left-side abdominal bruit and normal pulses in her extremities. Enalapril was discontinued upon hospital admission. Her renal recovery following emergent aortorenal sephenous vein grafts and pulse methylprednisolone has been reported. In 10/97, 90% stenosis of the right renal artery vein graft was treated successfully with angioplasty. At that time a slight stenosis of the mid portion of the right subclavian artery was noted. An MRI in 8/99 showed no further narrowing of the involved arteries. It is mentioned that the dx of Takayasu's arteritis fits well, as she was a young woman with angiographic abnormalties of the subclavian, celiac, superior mesenteria and renal arteries that are characteristic of Takayasu's. It was also mentioned that it is not possible to determine whether the large artery vasculitis in this pt was caused by the vaccination or simply temporally associated. The number of cases of vasculitis that have been reported following vaccination at least raises the possibility of a causal relationship. The underlying rheumatic diseases of both pts described in this article (ankylosing spondylitis for the present case and polymyalgia rheumation for the 2nd pt) suggests the possibility that the pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Anorexia, Aortic valve stenosis, Arteritis, Blood creatinine increased, Eye pain
Clinical narrative: In 9/97, a 1st dose of Engerix-B was given previous to a travel to India. At that time, the blood pressure was 110/70. Hep-B serologies were negative. The night following the 1st vaccination, this subject experienced fatigue, malaise and eye pain, which resolved over days. In 10/97, the 2nd dose of Engerix-B was given. Post vax, she rapidly developed fatigue as well as low-grade fevers, anorexia and headache. Over the next month, she experienced a weight loss of about 13.5 kg and by 11/97, she had developed hypertension (230/140). A retinal hemorrhage was noted. A rise in her serum creatinine to 2.8mg/dl prompted referral to the hospital. Exam in 2/98 showed blood pressure 140/104 in the right arm and 180/104 in the left arm. Bruits were noted over both axillary arteries, the left supraclavicular area, the left femoral artery and the abdomen. The right brachial and radial pulses were diminished. The serum creatinine was 2.8mg/dl and ESR 18mm/h. Angiography showed long bilateral subclavian stenosis with the right extending to the axillary artery. Bilateral selective renal angiogram in 11/98 showed evidence of arteritis in the small and large renal arteries. Despite being treated with prednisone and multiple immunosuppressive drugs including monthly pulse cyclophosphamide, her renal function continued to deteriorate and there was no change in the stenosis. Progressive renal failure was ascribed to her hypertension and underlying arteritis. Immunosuppressive therapy was discontinued in 6/99 and hemodialysis commenced 2 months later. She successfully underwent living related renal transplantation in 11/99. It is discussed that the above mentioned vasculitis in this pt also suggests Takayasu's arteritis. However, her advanced age and the sparing of other vessels would be unusual for Takayasu's. A dx of giant cell arteritis would fit her onset of disease after age 50 and the subclavian changes, which may occur in QCA in the absence of temporal artery involvement. However, QCA would not explain the bilateral renal artery disease this pt had. The underlying rheumatic disease of the pt in this article (polymyalgia rheumatica) suggests she possibility that a pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Fatigue, Headache, Hypertension, Laboratory test abnormal, Malaise
Clinical narrative: In 9/97, a 1st dose of Engerix-B was given previous to a travel to India. At that time, the blood pressure was 110/70. Hep-B serologies were negative. The night following the 1st vaccination, this subject experienced fatigue, malaise and eye pain, which resolved over days. In 10/97, the 2nd dose of Engerix-B was given. Post vax, she rapidly developed fatigue as well as low-grade fevers, anorexia and headache. Over the next month, she experienced a weight loss of about 13.5 kg and by 11/97, she had developed hypertension (230/140). A retinal hemorrhage was noted. A rise in her serum creatinine to 2.8mg/dl prompted referral to the hospital. Exam in 2/98 showed blood pressure 140/104 in the right arm and 180/104 in the left arm. Bruits were noted over both axillary arteries, the left supraclavicular area, the left femoral artery and the abdomen. The right brachial and radial pulses were diminished. The serum creatinine was 2.8mg/dl and ESR 18mm/h. Angiography showed long bilateral subclavian stenosis with the right extending to the axillary artery. Bilateral selective renal angiogram in 11/98 showed evidence of arteritis in the small and large renal arteries. Despite being treated with prednisone and multiple immunosuppressive drugs including monthly pulse cyclophosphamide, her renal function continued to deteriorate and there was no change in the stenosis. Progressive renal failure was ascribed to her hypertension and underlying arteritis. Immunosuppressive therapy was discontinued in 6/99 and hemodialysis commenced 2 months later. She successfully underwent living related renal transplantation in 11/99. It is discussed that the above mentioned vasculitis in this pt also suggests Takayasu's arteritis. However, her advanced age and the sparing of other vessels would be unusual for Takayasu's. A dx of giant cell arteritis would fit her onset of disease after age 50 and the subclavian changes, which may occur in QCA in the absence of temporal artery involvement. However, QCA would not explain the bilateral renal artery disease this pt had. The underlying rheumatic disease of the pt in this article (polymyalgia rheumatica) suggests she possibility that a pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Polymyalgia rheumatica, Pyrexia, Renal failure acute, Renal vasculitis, Retinal haemorrhage
Clinical narrative: In 9/97, a 1st dose of Engerix-B was given previous to a travel to India. At that time, the blood pressure was 110/70. Hep-B serologies were negative. The night following the 1st vaccination, this subject experienced fatigue, malaise and eye pain, which resolved over days. In 10/97, the 2nd dose of Engerix-B was given. Post vax, she rapidly developed fatigue as well as low-grade fevers, anorexia and headache. Over the next month, she experienced a weight loss of about 13.5 kg and by 11/97, she had developed hypertension (230/140). A retinal hemorrhage was noted. A rise in her serum creatinine to 2.8mg/dl prompted referral to the hospital. Exam in 2/98 showed blood pressure 140/104 in the right arm and 180/104 in the left arm. Bruits were noted over both axillary arteries, the left supraclavicular area, the left femoral artery and the abdomen. The right brachial and radial pulses were diminished. The serum creatinine was 2.8mg/dl and ESR 18mm/h. Angiography showed long bilateral subclavian stenosis with the right extending to the axillary artery. Bilateral selective renal angiogram in 11/98 showed evidence of arteritis in the small and large renal arteries. Despite being treated with prednisone and multiple immunosuppressive drugs including monthly pulse cyclophosphamide, her renal function continued to deteriorate and there was no change in the stenosis. Progressive renal failure was ascribed to her hypertension and underlying arteritis. Immunosuppressive therapy was discontinued in 6/99 and hemodialysis commenced 2 months later. She successfully underwent living related renal transplantation in 11/99. It is discussed that the above mentioned vasculitis in this pt also suggests Takayasu's arteritis. However, her advanced age and the sparing of other vessels would be unusual for Takayasu's. A dx of giant cell arteritis would fit her onset of disease after age 50 and the subclavian changes, which may occur in QCA in the absence of temporal artery involvement. However, QCA would not explain the bilateral renal artery disease this pt had. The underlying rheumatic disease of the pt in this article (polymyalgia rheumatica) suggests she possibility that a pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 61.0
Sex: F
Vaccine: HEP
Symptoms: Weight decreased
Clinical narrative: In 9/97, a 1st dose of Engerix-B was given previous to a travel to India. At that time, the blood pressure was 110/70. Hep-B serologies were negative. The night following the 1st vaccination, this subject experienced fatigue, malaise and eye pain, which resolved over days. In 10/97, the 2nd dose of Engerix-B was given. Post vax, she rapidly developed fatigue as well as low-grade fevers, anorexia and headache. Over the next month, she experienced a weight loss of about 13.5 kg and by 11/97, she had developed hypertension (230/140). A retinal hemorrhage was noted. A rise in her serum creatinine to 2.8mg/dl prompted referral to the hospital. Exam in 2/98 showed blood pressure 140/104 in the right arm and 180/104 in the left arm. Bruits were noted over both axillary arteries, the left supraclavicular area, the left femoral artery and the abdomen. The right brachial and radial pulses were diminished. The serum creatinine was 2.8mg/dl and ESR 18mm/h. Angiography showed long bilateral subclavian stenosis with the right extending to the axillary artery. Bilateral selective renal angiogram in 11/98 showed evidence of arteritis in the small and large renal arteries. Despite being treated with prednisone and multiple immunosuppressive drugs including monthly pulse cyclophosphamide, her renal function continued to deteriorate and there was no change in the stenosis. Progressive renal failure was ascribed to her hypertension and underlying arteritis. Immunosuppressive therapy was discontinued in 6/99 and hemodialysis commenced 2 months later. She successfully underwent living related renal transplantation in 11/99. It is discussed that the above mentioned vasculitis in this pt also suggests Takayasu's arteritis. However, her advanced age and the sparing of other vessels would be unusual for Takayasu's. A dx of giant cell arteritis would fit her onset of disease after age 50 and the subclavian changes, which may occur in QCA in the absence of temporal artery involvement. However, QCA would not explain the bilateral renal artery disease this pt had. The underlying rheumatic disease of the pt in this article (polymyalgia rheumatica) suggests she possibility that a pt with immunologic dysfunction may be more susceptible to developing vasculitis following vaccination.
Age: 0.2
Sex: M
Vaccine: DTAP, HBHEPB, IPV, PNC
Symptoms: Pyrexia, Viral infection
Clinical narrative: On 10/1/01 at 16:00, pt had a fever of 105F. He was admitted to the hospital. Pt was treated with IV antibiotics for 2 days. Dx'd with viral syndrome.
Age: 0.3
Sex: M
Vaccine: DTAP, HIBV, IPV
Symptoms: Convulsion, Speech disorder
Clinical narrative: Four days after immunization infant started having multiple seizures and was admitted to hospital, started on anti seizure meds and was weaned off after about 5 months. Now off over a year and without seizures. Child's speech delayed, neurologist feels related to seizures and seizures related to DTaP. Doc 213706, states the following: Delay in speech development. Problem continued more than 1 year after immunization. Report was made 23 mo. after immunization Annual follow up report received 6/10/2003 adds: Date of vaccination was 1/4/2000, date of VAERS report 12/3/01, had been 1 year 11 months between vaccine and report. Symptoms were still present at that time. 4/4/03 phone call to mother revealed child's speech was still delayed, was enrolled in a PPI program and currently being evaluated for autism. A follow up report received on 6/23/2003 adds: Enclosed is a follow-up report to a VAERS report that I submitted on 12/03/2001. At that time, it had been 1 year 11 months since the child had received the vaccine. His mother was concerned the child was still having problems related to immunization. I contacted the mother again on 04/04/2003 for follow up (3 years, 4 months from vaccination date). She states child is no longer on seizure medication and has had no further seizure activity. He still has speech delays and is enrolled in a Pre-Primary Impaired program. He has an appointment to evaluate further for autism. She has chosen note to continue immunizations.  Follow up on 10/31/2003: "Vaccine recipient did not recover from the adverse events.  Date of vaccination was 01/04/2000.  Date of VAERS report 12/03/2001.  Had been 1 year 11 months between vaccine and report symptoms were still present at that time.  04/04/2003: Phone call to mother revealed child's speech was still delayed, was enrolled in a PPI program and currently being evaluated at hospital for autism."
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Difficulty in walking, Muscular weakness
Clinical narrative: Upon waking, on 11/12/99, the pt experienced both legs "buckled" and had difficulty walking. Symptoms progressed by evening and was unable to stand. By the next day, she loss use of her arms and hands. Treatment (IV solution of platelet Ig concentrate) started immediately with some return of feeling in a week. Went to inpatient after 11 days in ICU. She is using walker. Fully recovered and back to work on 3/1/00. She felt "self again" in 5/01.
Age: 71.0
Sex: F
Vaccine: FLU3
Symptoms: Balance disorder, Guillain-Barre syndrome, Pain in extremity, Paraesthesia
Clinical narrative: Reported pt diagnosed with Guillain-Barre syndrome. Per 1 year ago: Pt has not recovered. "Continues to be off-balance. Bottoms of my feet are painful and they tingle with my toes wanting to draw under. My hands still tingle."
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR, PNC
Symptoms: Anaphylactic reaction
Clinical narrative: Pt developed anaphylaxis, 5 minutes post vax.
Age: 44.0
Sex: M
Vaccine: LYME
Symptoms: Arthralgia, Brain oedema, Cognitive disorder, Depression, Fatigue
Clinical narrative: Pt developed immediate sore joints, extreme cognitive decline and depression. Within 1 week, he developed extreme fatigue. Within 1 month he had tingling of his arm, facial tics and an inflamed elbow with extreme pain. Poor cognitive function, no memory, joints hurt. Constantly "sick" since receiving the lyme vaccine. In April, May and June of 1999. Brain swelling. Cannot work.
Age: 44.0
Sex: M
Vaccine: LYME
Symptoms: Inflammation, Pain, Paraesthesia, Tic
Clinical narrative: Pt developed immediate sore joints, extreme cognitive decline and depression. Within 1 week, he developed extreme fatigue. Within 1 month he had tingling of his arm, facial tics and an inflamed elbow with extreme pain. Poor cognitive function, no memory, joints hurt. Constantly "sick" since receiving the lyme vaccine. In April, May and June of 1999. Brain swelling. Cannot work.
Age: 19.0
Sex: M
Vaccine: TTOX, YF
Symptoms: Dyspnoea, Hypersensitivity, Pruritus, Urticaria
Clinical narrative: First noted hives and itching on arms, face at 11:00 AM one hour after injection, reported to Clinic at 14:00 hours with above signs at symptoms reversible complained of SOB OR difficult breathing. Pt given one Claritin 10 mg by mouth. Pt states decreased S/J within 15 minutes with medication.
Age: 86.0
Sex: M
Vaccine: FLU3
Symptoms: Haemorrhage, Skin discolouration
Clinical narrative: 120x70 mm hematoma on right arm area. No soreness, no numbness or tingling of extremity area dark purple with yellowing with edges. To flu with pink in 1-2 days.
Sex: F
Vaccine: FLU3
Symptoms: Injection site oedema
Clinical narrative: Check out swollen area on arm.
Age: 70.0
Sex: F
Vaccine: FLU3, PPV
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: The pt complained of soreness, swelling and redness on left arm between elbow and upper arm the day after injections.
Age: 59.0
Sex: F
Vaccine: FLU3
Symptoms: Hypokinesia, Injection site pain
Clinical narrative: The pt complained of soreness at the site of the injection. She called on 12/31/01 and said that she had difficulty in raising her arm. She was vaccinated on 11/7/01.
Age: 57.0
Sex: F
Vaccine: FLU3
Symptoms: Rash
Clinical narrative: 11/1/01 pt reported having a light red rash all over her body. Dry rash.
Age: 50.0
Sex: F
Vaccine: FLU3
Symptoms: Dizziness, Syncope
Clinical narrative: The pt experienced a syncopal episode about 15-20 minutes after flu shot and about 5 minutes after blood was drawn complicated by difficulty accessing vein X 3 attempts. The pt felt dizzy prior to episode. The event was attributed to vasovagal reaction.
Age: 21.0
Sex: M
Vaccine: FLU3
Symptoms: Asthenia, Hypersensitivity, Pain, Pruritus, Rash
Clinical narrative: Rash, itching muscle aches, fatigue.
Age: 54.0
Sex: M
Vaccine: FLU3
Symptoms: Arthritis, Ear pain, Headache, Musculoskeletal stiffness
Clinical narrative: The pt called the clinic on 11/6/01 and stated he "has had stiff neck and soreness of head and ears since 11/3/01. He states he has arthritis of neck and he was referred to PMD. Called PMD but the pt did not go. Then PMD's office called and stated the pt was seen on 11/3/01 with no complaints.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Injection site pain, Injection site swelling
Clinical narrative: 11/28/01 @ 1:35 came in for swollen,painful L arm after flu shot. Ice packs and advil tabs po q 6 hrs, prn. 12/3/01 pt called, doing fine now.
Age: 31.0
Sex: F
Vaccine: FLU3
Symptoms: Arthropathy, Chills, Headache, Mouth ulceration, Vasculitis
Clinical narrative: Stiff neck, 11/20/2001, 6PM, 9:00AM awaking 11/21/01 vasculitis lower extremity (legs), stiff neck, headache, cold, by 11/25/01 on forearms, buttocks, stomach, lower back, but spoatic, 11/29/01 3 painless ulcers in roof of mouth.
Age: 1.4
Sex: M
Vaccine: FLU3, VARCEL
Symptoms: Convulsion
Clinical narrative: Seven minute tonic-clonic seizure. No documented fever. Twin sibling has had 2 febrile seizures.
Age: 45.0
Sex: F
Vaccine: FLU3
Symptoms: Hyperaesthesia, Pain, Rash maculo-papular, Vasodilation procedure
Clinical narrative: Received influenza vaccine 10/15/2001 left upper arm. Same evening painful, warm to touch. Next day 10/16/2001 large reddened, hardened raised area 10/17/2001. Some reddened area not raised 2 inches in diameter. Took Tylenol.
Age: 68.0
Sex: M
Vaccine: FLU3
Symptoms: Chills, Sensation of pressure
Clinical narrative: Pt received vaccine on 10/24/2001 in AM. That evening pt experienced increased intestinal and bladder pressure for 2 days with chills, after which symptoms resolved.
Age: 61.0
Sex: M
Vaccine: FLU3
Symptoms: Asthenia, Joint range of motion decreased
Clinical narrative: Received flu shot left deltoid 11/15/2001. On 12/03/2001 complained of weakness in arm, difficulty raising arm, decreased strength. Saw ARNP 11/26/2001. Treated with warm compress. NKA. On 12/06/2001 improved.
Age: 28.0
Sex: F
Vaccine: FLU3
Symptoms: Chest discomfort, Throat tightness
Clinical narrative: Pt developed chest and throat tightness about 8 minutes after receiving flu vaccine. Epinephrine 0.3cc given.
Age: 43.0
Sex: F
Vaccine: FLU3
Symptoms: Contusion, Injection site hypersensitivity, Oedema, Vasodilation procedure
Clinical narrative: Complained of red mark, hot area of upper arm, area is black and blue and swollen the size of a fist.
Age: 4.0
Sex: F
Vaccine: DTAP, FLU3, IPV, MMR
Symptoms: Cellulitis
Clinical narrative: Cellulitis of left thigh. Benadryl PO q 4-6 hours. Keflex 250 mg TID for 7 days. Warm soaks.
Age: 45.0
Sex: F
Vaccine: FLU3
Symptoms: Dehydration, Diarrhoea, Dizziness, Nausea, Vomiting
Clinical narrative: 1:30 AM woke up nauseated, vomited, had diarrhea. Continued for 2 weeks. 11/15/2001 IV for dehydration-NS. Continues to be dizzy and complains of nausea.
Sex: M
Vaccine: FLU3
Symptoms: Dermatitis allergic, Influenza like illness
Clinical narrative: Allergic dermatitis and flu-like symptoms.
Age: 75.0
Sex: M
Vaccine: FLUX
Symptoms: Aspartate aminotransferase increased, Ecchymosis, Epistaxis, Mouth haemorrhage, Platelet count decreased
Clinical narrative: The pt presented to my office quite unexpectedly on 11/20/01 with complaints of worsening ecchymosis and bleeding from his mouth and nose. A stat CBC showed a platelet count of 8,000. Two weeks earlier, his platelets were stable at 68,000 while on Danocrine 200mg daily and prednisone, 5mg daily. In taking a history from the pt, the only thing new was the fact that he had received an influenza vaccination approx. 2 weeks earlier. What was quite fascinating was the fact that the day before, another pt of mine with a history  of ITP, also presented to my office with a relapse of his disease 12-14 days after an influenza vaccination. I took the liberty of treating the pt with high dose IG IV, I raised his dose of prednisone, gave him 1 dose of Vincristine and 2 units of platelet transfusion because of his bleeding. On 11/27/01, his platelet count was still low at 6,000. He then received a dose of WinRho as an outpatient on 11/27/01. On 11/29/01, his platelets were still low. Test showed elevated Transaminases of uncertain etiology which could certainly be due to the Danocrine or to perhaps the WinRho. I will ask the pt to discontinue the Danocrine at this time and raised his prednisone to 80mg/day. Platelets were up to 40,000 on 12/3/01. In 17 years of practice, I have never seen this. This is considered to be an "Other Important Medical Event".
Age: 75.0
Sex: M
Vaccine: FLUX
Symptoms: Thrombocytopenic purpura
Clinical narrative: The pt presented to my office quite unexpectedly on 11/20/01 with complaints of worsening ecchymosis and bleeding from his mouth and nose. A stat CBC showed a platelet count of 8,000. Two weeks earlier, his platelets were stable at 68,000 while on Danocrine 200mg daily and prednisone, 5mg daily. In taking a history from the pt, the only thing new was the fact that he had received an influenza vaccination approx. 2 weeks earlier. What was quite fascinating was the fact that the day before, another pt of mine with a history  of ITP, also presented to my office with a relapse of his disease 12-14 days after an influenza vaccination. I took the liberty of treating the pt with high dose IG IV, I raised his dose of prednisone, gave him 1 dose of Vincristine and 2 units of platelet transfusion because of his bleeding. On 11/27/01, his platelet count was still low at 6,000. He then received a dose of WinRho as an outpatient on 11/27/01. On 11/29/01, his platelets were still low. Test showed elevated Transaminases of uncertain etiology which could certainly be due to the Danocrine or to perhaps the WinRho. I will ask the pt to discontinue the Danocrine at this time and raised his prednisone to 80mg/day. Platelets were up to 40,000 on 12/3/01. In 17 years of practice, I have never seen this. This is considered to be an "Other Important Medical Event".
Age: 5.0
Sex: M
Vaccine: FLU3, PNC
Symptoms: Injection site erythema, Injection site mass, Injection site warmth
Clinical narrative: Mother of child states 11/15 size of a dime large lump with redness developed on R arm at injection site. It continued to increase in size on 11/16 became very warm to touch 3 large half dollar size blotches were present. 11/17 began to resolve and now completely gone without further complications.
Age: 1.9
Sex: F
Vaccine: DTAP, IPV, PNC
Symptoms: Convulsion, Postictal state
Clinical narrative: 23 month old adopted from China on 10/00 with reliable government immunization records. On 12/4/01, at around 08:00, the pt had a 2 minute generalized seizure. This was a 1st time seizure. She was postictal for several hours in the ER. No other signs or symptoms. Afebrile.
Age: 0.4
Sex: M
Vaccine: DTAP, HBHEPB, IPV, PNC
Symptoms: Hypokinesia, Irritability, Pyrexia, Viral infection
Clinical narrative: Pt started with a fever of 103F-104F on 12/3/01 and continues with a fever, fussiness and decreased activity. He saw doctor on 12/5/01 and was dx'd with "viral illness". He still is with increased temperature.
Age: 0.3
Sex: F
Vaccine: DTAP, HBHEPB, IPV, PNC
Symptoms: Crying, Injection site nodule
Clinical narrative: High pitched uncontrollable crying - 2 1/2 hrs, small reddened nodule on R anterior thigh.
Age: 2.0
Sex: M
Vaccine: DTAP, MMR, PNC
Symptoms: Cellulitis, Injection site erythema, Injection site swelling, Rash macular
Clinical narrative: Pt had redness, rash and a raised 5cm X 7cm macular rash medial to injection site. He was placed on oral Keflex for cellulitis.
Age: 4.0
Sex: M
Vaccine: DT
Symptoms: Hypersensitivity, Injection site mass, Pruritus
Clinical narrative: Right area that itched around injection site. was 4x areas most of upper arm got pink, indurated and itched.
Sex: F
Vaccine: PPV
Symptoms: Injection site erythema, Injection site swelling, Injection site warmth
Clinical narrative: Shot given in L deltoid/ IM early AM. By 5pm arm 1" below shot site swollen, red, warm painful.
Age: 1.0
Sex: M
Vaccine: HEP, MMR, VARCEL
Symptoms: Rash maculo-papular
Clinical narrative: Pt developed a maculopapular, discreet rash on 12/04/2001. No fever or other symptoms.
Age: 8.0
Sex: M
Vaccine: UNK
Symptoms: Rash papular
Clinical narrative: Seen by primary care physician on 11/28/01. Diagnoses with atypical varicella. Trunk with erythemotous popular lesions with some scabs, few vesicles.