Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Arthralgia, Herpes zoster, Insomnia, Neuralgia, Pruritus
Clinical narrative: Excrutiating joint pain; experience itching that waxes and wanes; pain was enought to wake her up at night; shingles/she broke out in the shingles rash; mild rash; severe nerve pain; This case was reported by a consumer via call center representative and described the occurrence of shingles in a 76-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included muscle injury. Previously administered products included Zostavax (received 5 years ago). Concurrent medical conditions included pain (still experiencing the pain and still thought it was an injury).   On 2nd October 2019, the patient received Shingrix. On 3rd October 2019, 1 days after receiving Shingrix, the patient experienced shingles and rash. In October 2019, the patient experienced nerve pain. On an unknown date, the patient experienced joint pain, pruritus and difficulty sleeping. The patient was treated with antivirals nos. On an unknown date, the outcome of the shingles was recovered/resolved and the outcome of the joint pain was not recovered/not resolved and the outcome of the nerve pain, pruritus, rash and difficulty sleeping were unknown.   It was unknown if the reporter considered the shingles, nerve pain, pruritus, rash and difficulty sleeping to be related to Shingrix. The reporter considered the joint pain to be related to Shingrix.  Additional details were provided as follows: The patient received Shingrix and came down with the shingles the next day.   The patient did not believe that the Shingrix caused the shingles.  She believes she was coming down with shingles a few days before having the vaccine.   She also experienced excrutiating joint pain after getting the Shingrix vaccine. She still has it. The patient visited the emergency room 2 days prior to getting the vaccine. The next day she broke out in the shingles rash and she realized that she was already coming down with shingles when she got the vaccine. She thinks the vaccine exacerbated the case of shingles because she had a very severe case with the rash going across from her naval to her spine and down from the T4 vertebrae to the iliac crest. She was treated with a 7 days course of antiviral and the rash cleared up some. While taking the antiviral she did not experience pain, but once she completed the antiviral course she did develop the severe nerve pain. The rash did not fully clear up and after several weeks she took another 7 day course of antiviral. The 2nd course of antiviral cleared up the rash more and stopped most of the pain. She did not have pain from the shingles, but she experience itching that waxes and wanes and she still has a mild rash. In addition to shingles she also developed severe joint pain after getting the vaccine. The joint pain was enough to wake her up at night. She has never experienced joint pain before. The joint pain was subsiding, but still present. She thinks the joint pain was related to Shingrix, but not the case of shingles she experienced. She was currently in very good physical condition. She did not generally have any joint pain and exercises regularly.