Age: 71.0
Sex: F
Vaccine: COVID19
Symptoms: Injection site erythema, Injection site swelling, Injection site vesicles, Injection site warmth
Clinical narrative: 6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.; 6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.; 6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.; 6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.; This spontaneous case was reported by a patient and describes the occurrence of INJECTION SITE VESICLES (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE WARMTH (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE SWELLING (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.) and INJECTION SITE ERYTHEMA (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.) in an elderly female patient who received mRNA-1273.815 (SPIKEVAX 2023-2024) (batch no. ASKU) for COVID-19 prophylaxis.     Patient took medication for each condition. Patient also takes ambient for sleep.  Previously administered products included for Product used for unknown indication: Covid-19 vaccine (Lot number: -0311420A and Dose 1) on 11-Feb-2021. Past adverse reactions to the above products included No adverse event with Covid-19 vaccine. Concurrent medical conditions included Blood pressure high, Depression, Anxiety, Hypothyroidism, Cholesterol and Sleep disorder. Concomitant products included ZOLPIDEM TARTRATE (AMBIEN) for Sleep disorder, INFLUENZA VACCINE and RSV VACCINE for an unknown indication.    On 07-Nov-2023 at 10:30 AM, the patient received fifth dose of mRNA-1273.815 (SPIKEVAX 2023-2024) (unknown route) 1 dosage form. On 07-Nov-2023 at 4:30 PM, the patient experienced INJECTION SITE VESICLES (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE WARMTH (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE SWELLING (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.) and INJECTION SITE ERYTHEMA (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.). The patient was treated with NAPROXEN SODIUM (ALEVE) at an unspecified dose and frequency. At the time of the report, INJECTION SITE VESICLES (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE WARMTH (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.), INJECTION SITE SWELLING (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.) and INJECTION SITE ERYTHEMA (6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site.) had not resolved.            It was reported that patient receives other vaccines in the 4 weeks prior to COVID-19 vaccine.  Patient receives moderna covid-19 vaccine 2nd dose on 11-Mar-2021 (lot number: - 040A21A), 3rd dose on 22-Oct-2021 (lot number: - 012F21A) and 4th dose on 19-Apr-2022 (lot number: - 057M21A).  It was reported that the shot went right with no pain. She came home and took an Aleve (She read it was recommended after the shot to help with onset of something you did not want). She put an ice pack on the injection site. 6 hours later it turns red, hot to the touch and swollen. She developed a blister in the middle of the red area, possibly at the actual injection site. She went to the pharmacy and the pharmacist stated she should wait 24 hours before seeing a physician.