Sex: F
Vaccine: HEP, HEPA, HPV4, MMR, MMRV, PPV, VARCEL
Symptoms: Lactose intolerance, Nausea, Skin test negative, Vaccination site erythema, Vaccination site pain
Clinical narrative: Vaccination site soreness; Vaccination site redness; Vaccination site swelling; Allergic to GARDASIL; Allergic to penicillin; Lactose intolerance; Acute nonintractable headache, unspecified headache type; Nausea; Dizziness; This spontaneous report was received via pfizer from a consumer regarding herself, a female patient of unknown age. No information was provided regarding the patient's medical history, concurrent conditions, or concomitant medications. The patient was allergic to amoxicillin, penicillin, sulfamethoxazole-trimethoprim, azithromycin and cefdinir.  On 28-DEC-2005, the patient was vaccinated with Hepatitis B Vaccine (Recombinant) (manufacturer unknown) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported).  On 15-FEB-2006, the patient was vaccinated with Pneumococcal Vaccine, Polyvalent (23-valent) (manufacturer unknown) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported), haemophilus influenzae type b (Hib).  On 22-MAR-2006, the patient was vaccinated with Hepatitis B Vaccine (Recombinant) (manufacturer unknown), Diphtheria (+) Tetanus (+) Pertussis (DTaP) and inactivated poliovirus vaccine (IPV).  On 24-MAY-2006, the patient was vaccinated with Hepatitis B Vaccine (Recombinant) (manufacturer unknown), Diphtheria (+) Tetanus (+) Pertussis (DTaP) and haemophilus influenzae type b (Hib).  On 08-AUG-2006, the patient was vaccinated with Pneumococcal Vaccine, Polyvalent (23-valent) (manufacturer unknown), Diphtheria (+) Tetanus (+) Pertussis (DTaP), haemophilus influenzae type b (Hib) and inactivated poliovirus vaccine (IPV).  On 06-NOV-2006, the patient was vaccinated with Pneumococcal Vaccine, Polyvalent (23-valent) (manufacturer unknown) and influenza vaccine.  On 26-JAN-2007, the patient was vaccinated with Hepatitis A Vaccine, Inactivated (manufacturer unknown) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported) and with Pneumococcal Vaccine, Polyvalent (23-valent) (manufacturer unknown).  On 28-JAN-2007, the patient was vaccinated with varicella virus vaccine live (Oka/Merck) (manufacturer unknown) (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported).  On 13-APR-2007, the patient was vaccinated with Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (manufacturer unknown) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported) and haemophilus influenzae type b (Hib).  On 13-JUL-2007, the patient received Diphtheria (+) Tetanus (+) Pertussis (DTaP).  On 28-SEP-2007, the patient received a second dose of Hepatitis A Vaccine, Inactivated (manufacturer unknown) for prophylaxis (strength, dose number, anatomical location, route of administration, lot number and expiration date were not reported).  On 24-MAY-2008, the patient was vaccinated with haemophilus influenzae type b (Hib), inactivated poliovirus vaccine (IPV) and inactivated poliovirus vaccine (IPV).  On 12-OCT-2009, the patient received the influenza vaccine.  On 19-DEC-2009, the patient was vaccinated with influenza a(h1n1)pdm09 vaccine inact.  On 11-MAY-2010, the patient was vaccinated with Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (manufacturer unknown).  On 05-NOV-2010, the patient was vaccinated with Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (PROQUAD), varicella virus vaccine live (Oka/Merck) (manufacturer unknown), Diphtheria (+) Tetanus (+) Pertussis (DTaP), inactivated poliovirus vaccine (IPV) and influenza vaccine.  On 10-OCT-2011, the patient received the influenza vaccine.  On 22-AUG-2017, the patient was vaccinated with Diphtheria (+) Tetanus (+) Pertussis (DTaP).   On 23-AUG-2017, the patient was vaccinated with first dose, 0.5 milliliters of Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) for prophylaxis (strength, anatomical location, route of administration, lot number and expiration date were not reported) and meningococcal conjugate (MENACTRA).  On an unknown date, the patient experienced and allergy to Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) with redness, soreness and very visible swelling at the vaccination site with nausea, headache  and dizziness for a month; consequently it was decided to no receive the second dose.  On 24-JUN-2021, the patient the patient underwent the percut allergy that showed a skin test negative and that she was allergic to penicillin (drug hypersensitivity). On an unspecified date, the patient experienced lactose intolerance and the doctor advised her to take lactaid tablets.   The outcome of the events nausea and dizziness resolved on an unknown date and for the remaining events the outcome was not provided.  The reporter assessed the causal relationship between vaccination with Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recomb. Vaccine (GARDASIL) and the events allergy to vaccine, redness, soreness and swelling at the vaccination site, nausea and dizziness as related but for headache, drug hypersensitivity and lactose intolerance the causality was unknown. Regarding the causality between the other suspect vaccines with all the events information was not provided.  The patient had a history of overdose on vaccination with Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (PROQUAD) and varicella virus vaccine live (Oka/Merck) (manufacturer unknown) (case # 2108USA000378) and extra dose administered with inappropriate schedule of product administration on vaccination with Pneumococcal Vaccine, Polyvalent (23-valent) (manufacturer unknown).; Sender's Comments:  US-009507513-2108USA000378: US-009507513-2108USA000377: