Age: 32.0
Sex: F
Vaccine: FLUC3
Symptoms: Rash, Rash erythematous, Rash papular, Rash pruritic
Clinical narrative: Shortness of breath; Chest tightness; Itchy eyes; Swelling in arm at injection site; Itchy raised red rash from tip of nose to eyebrows; Itchy raised red rash from tip of nose to eyebrows; Itchy raised red rash from tip of nose to eyebrows; Watery eyes; This spontaneous case was retrieved on 06-Sep-2022 from Vaccine Adverse Event Reporting System (VAERS) (reference number 0919693-1), reported by other healthcare professional, and concerned a 32-year-old, female patient.  The patient's concurrent conditions included asthma and penicillin allergy. The patient's concomitant medications were not reported.  On 29-Dec-2020 the patient was vaccinated with Flucelvax Quadrivalent (influenza vaccine inact sag 4v; route of administration: intramuscular, anatomical location: left arm, dose and indication: not reported). The batch number reported was 276558 (reported batch number was identified by Seqirus to be linked to suspect product Flucelvax Quadrivalent instead of reported suspect product Fluad Quadrivalent.  On 30-Dec-2020, one day after receiving Flucelvax Quadrivalent, the patient experienced itchy eyes, swelling in arm at injection site, itchy raised red rash from tip of nose to eyebrows and watery eyes.   On 31-Dec-2020, two days after receiving Flucelvax Quadrivalent, the patient developed chest tightness and shortness of breath. The patient treated symptoms with Benadryl (diphenhydramine hydrochloride) regularly and rescue inhaler she had for asthma as needed.   On 02-Jan-2021, the patient recovered from the events of chest tightness and shortness of breath, as reported it was improved with inhaler and lasted until Saturday.  At the time of initial reporting, the patient had not recovered from the events of itchy eyes, watering eyes, red rash, raised rash and itchy rash, while she was recovering from the event vaccination site swelling.  The reporter did not provide causality assessment.  The case was assessed as non-serious.  Company comment: A 32-year-old, female patient was vaccinated with Flucelvax Quadrivalent. One day following vaccination, the patient experienced itchy eyes, vaccination site swelling, itchy raised red rash and watery eyes. Next day, the patient developed chest tightness and shortness of breath. Reportedly, chest tightness and shortness of breath improved with inhaler. The patient's concurrent condition of asthma may have contributed to the development of the events. Nevertheless, causal role of the suspect vaccine cannot be excluded and is assessed as possibly related for all events, due to biological and chronological plausibility.; Sender's Comments: A 32-year-old, female patient was vaccinated with Flucelvax Quadrivalent. One day following vaccination, the patient experienced itchy eyes, vaccination site swelling, itchy raised red rash and watery eyes. Next day, the patient developed chest tightness and shortness of breath. Reportedly, chest tightness and shortness of breath improved with inhaler. The patient's concurrent condition of asthma may have contributed to the development of the events. Nevertheless, causal role of the suspect vaccine cannot be excluded and is assessed as possibly related for all events, due to biological and chronological plausibility.