Age: 72.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site pain, Mobility decreased, Muscle contracture, Sleep disorder
Clinical narrative: muscle in her body was constricting; Thought was suffering aneurism and was going to die; shivering; no energy; no appetite; sweating; Awoke at 2am, at 5:30am; arm was sore at the injection site; Couldnt put hand on bed, feet on floor it was so bad; This non-serious case was reported by a consumer via call center representative and described the occurrence of injection site pain in a 72-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   On 14-MAR-2023, the patient received the 2nd dose of Shingrix (intramuscular, left arm) .5 ml. On 14-MAR-2023, immediately after receiving Shingrix, the patient experienced injection site pain (Verbatim: arm was sore at the injection site). On 15-MAR-2023, the patient experienced muscle contracture (Verbatim: muscle in her body was constricting), impending doom (Verbatim: Thought was suffering aneurism and was going to die), shivering (Verbatim: shivering), loss of energy (Verbatim: no energy), appetite absent (Verbatim: no appetite), sweating (Verbatim: sweating) and sleep disorder (Verbatim: Awoke at 2am, at 5:30am). In MAR-2023, the patient experienced mobility decreased (Verbatim: Couldnt put hand on bed, feet on floor it was so bad). On 15-MAR-2023, the outcome of the muscle contracture was recovered/resolved (duration 2 hrs). The outcome of the injection site pain, shivering, loss of energy, appetite absent and sweating were recovered/resolved and the outcome of the impending doom, sleep disorder and mobility decreased were not reported.   It was unknown if the reporter considered the injection site pain, muscle contracture, impending doom, shivering, loss of energy, appetite absent, sweating, sleep disorder and mobility decreased to be related to Shingrix.     It was unknown if the company considered the injection site pain, muscle contracture, impending doom, shivering, loss of energy, appetite absent, sweating, sleep disorder and mobility decreased to be related to Shingrix.   Additional Information: GSK receipt date: 16-Mar-2023 The patient had received her second Shingrix vaccine and reported that her arm was sore at the injection site right after she received the Shingrix vaccine.  The patient went to bed that night a awoke at 2 am and reported every muscle in her body was constricting for about 2 hours.  During that time, the patient thought she was suffering and aneurism and was going to die.  The patient reported that she could not even put her hand on the bed or feet on the floor it was so bad and went back to sleep and got up at 5:30 am to use the bathroom and she noticed she was shivering and went back to bed.  The shivering resolved that morning, but she had no energy to do anything.  The patient also reported that no appetite, but she did drink water all day.  On day before the reporting, last night, she again awoke at 2 am and her sheets, nightgown and especially her pillows were really wet from her sweating.  The patient did not gave permission to contact her health care professional since she did not contact her.  The patient would be glad to answer any questions on her experiences, email provided. The reporter did not consent to follow-up.