Age: 39.0
Sex: F
Vaccine: MMR
Symptoms: Cellulitis, Injection site erythema, Injection site pain, Oedema peripheral
Clinical narrative: Information has been received from a 39 year old female nurse with previous "reactions to multiple vaccines" who on 18-DEC-2007 was vaccinated with a fifth dose of measles virus vaccine live (Enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus vaccine live (Wistar RA 27/3). The patient reported that after receiving her fifth dose of measles virus vaccine live (enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus vaccine live (Wistar RA 27/3) because she did not have a titer, she experienced redness at the injection site and her right upper deltoid was swollen the size of a baseball. The experience occurred within 24 hours of vaccination. Unspecified medical attention was sought. The patient was given antibiotics and BENADRYL. The patient reported that she had an "allergic reaction with previous injections." The outcome was reported as improved but not total resolved, recovering. No lot number was provided. There was no product quality complaint. In follow-up information from a physician, it was reported that the 39 year old patient with a penicillin allergy experienced severe cellulitis, which required an emergency room/doctor visit. The patient subsequently recovered. There was no illness at the time of vaccination. Additional information has been requested. This is in follow-up to report (s) previously submitted on 5/30/2008.  Information has been received from a 39 year old female nurse with previous "reaction to multiple vaccines" who on 20-DEC-2007 at 12:30 PM (also reported as 18-DEC-2007) was vaccinated SC with a fifth (also reported as second) dose of measles virus vaccine live (Enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus live (Wistar RA 27/3) (rHA) (Lot # 657138/0865U).  There was no illness at the time of vaccination.  The patient reported that after receiving her fifth dose of measles virus vaccine live (Enders-Edmonston) (+) mumps virus vaccine live (Jeryl Lynn) (+) rubella virus vaccine live (Wistar PA 27/3) because she did not have a titer, she experienced redness at the injection site and her right upper deltoid was swollen the size of a baseball.  The experienced occurred within 24 hours of vaccination.  Unspecified medical attention was sought.  The patient was given antibiotics and BENADRYL.  The patient reported that she had an "allergic reaction with previous injections".  The outcome was reported as improved but not totally resolved, recovering.  No lot number was provided.  There was no product quality complaint.  In follow-up information from a physician.  It was reported that the 39 year old white patient with a penicillin allergy experienced severe cellulitits, which required an emergency room/doctor visit.  The patient subsequently recovered.  There was no illness at the time of vaccination.  Follow up information indicated that on 20-DEC-2008, the patient experienced swelling and tenderness at the injection site.  Severe cellulitis was noted.  ROCEPHEN was adminstered IM to treat, along with CEPHALEXIN oral.  The patient recovered.  No additional information is expected.