Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Computerised tomogram normal, Discomfort, Feeling abnormal, Herpes zoster, Loss of consciousness
Clinical narrative: stomach hot to the touch; Discomfort; when she got up in the morning she was a zombie; knocked the patient out; Internal shingles affecting nerves in the abdomen and rib area; pain in sides (left) and ribs (middle), CAT scans / MRI normal; Rib pain; This case was reported by a consumer via call center representative and described the occurrence of loss of consciousness in a 76-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included chickenpox (had chicken pox (as a child)).   In March 2022, the patient received the 1st dose of Shingrix (intramuscular). In April 2022, less than a week after receiving Shingrix, the patient experienced pain and rib pain. On an unknown date, the patient experienced loss of consciousness (serious criteria GSK medically significant), shingles, skin warm, discomfort and felt like a zombie. The patient was treated with medication unknown (Epidural) and gabapentin. On an unknown date, the outcome of the loss of consciousness, felt like a zombie and rib pain were unknown and the outcome of the pain, shingles and skin warm were not recovered/not resolved and the outcome of the discomfort was recovering/resolving.   It was unknown if the reporter considered the loss of consciousness, pain, shingles, skin warm, discomfort, felt like a zombie and rib pain to be related to Shingrix.     Additional Information: GSK Receipt Date: 03-Aug-2022 Reporter's Comments: The reporters were the patient and her husband. They were both on the phone; they did not want to share their email address. The patient received Shingles shot 1 on an unknown date in March 2022 in the left deltoid muscle. Reporters did not have the lot number or the exact date of the injection but did provide the pharmacy where the injection was given as well as the primary care doctor who may have that data on file. Two to three days after receiving the shot in April 2022 the patient came down with pain in her sides and ribs, the patient had seen more than one doctor regarding this. The patient had seen her primary care doctor and a pain specialist. The pain specialist gave her an epidural which worked somewhat but did not resolve the pain completely. The patient had 2 cat scans (chest and abdomen) and an MRI and all the results came back normal. The patient's husband stated that the family doctor had prescribed many medications but they knocked the patient out and when she got up in the morning she was a zombie. The patient said, that she was prescribed with gabapentin 100 mg, then 300 mg, which took some of the discomfort away. The patient further stated that there was no rash nor had there ever been a rash but that the doctors felt that that it was internal shingles' affecting the nerves (in the) abdomen and rib area. The patient's husband reported that, the patients pain had not gone away completely that he could touch her stomach and it was hot and it stayed hot and he could fry an egg on it because it is so hot to the touch. The patient said that at the time of reporting her pain was mostly from the middle of her body and was the left side only, the pain had not let up (not resolved). The reporter consented to follow up.