Age: 51.0
Sex: F
Vaccine: COVID19
Symptoms: Jaundice, Liver disorder, Liver function test, Magnetic resonance cholangiopancreatography, Nausea
Clinical narrative: the Covid vaccine her labs for her liver were normal and 2 weeks after taking 1st dose, they are not normal.; Elevated Bilirubin and Liver Enzymes; Elevated Bilirubin and Liver Enzymes; Rapid Weight Loss without Trying; Nauseous; underlying constant level of nausea, like anxiety tummy where you can't eat low level nausea, no appetite, unable to eat much; Nauseous; underlying constant level of nausea, like anxiety tummy where you can't eat low level nausea, no appetite, unable to eat much; Fatigue; Jaundice; This is a spontaneous report from a contactable consumer (patient) via Pfizer sponsored Program. A 51-years-old female patient received bnt162b2 (Pfizer-BioNTech COVID-19 Vaccine, solution for injection), dose 1 via an unspecified route of administration, administered in Arm Left on 28Jan2021 (at the age of 51-years-old) (Lot Number: EL9263) as DOSE 1, SINGLE, dose 2 via an unspecified route of administration, administered in Arm Left on 17Feb2021 (at the age of 51-years-old) (Lot Number: EL9267) as DOSE 2, SINGLE for covid-19 immunisation. Medical history included food poisoning from an unknown date and unknown if ongoing and vomiting from 18Jan2021 to an unknown date (also on 19Jan2021, 20Jan2021). There were no concomitant medications. She stated that she doesn't get sick, so it was weird, no colds, rarely gets anything, for her to feel bad it was super strange and what started all of this. She states that before her vaccine, she got something like a significant food poisoning, states she thought she had Covid, she was surprised when it came back negative. States on 18Jan, 19Jan, 20Jan she had vomiting, and she thought it was Covid, stated she had every single symptom and couldn't keep coffee down and had fever, chills, and vomiting. So, she went for a Covid test on 20Jan2021 and hunkered down and was ready to quarantine but the test was negative. Stated a week later she went and got the vaccine on 28Jan2021. She stated that she heard that there was some little stomach bug going around and she felt better after 3 days. The patient had not received any other vaccine within 4 weeks. On an unspecified date, caller said before taking the Covid vaccine her labs for her liver were normal and 2 weeks after taking 1st dose, they are not normal. She was wondering if this could be a side effect. The patient had jaundice on 14Feb2021, Stated friends asked if she had been tanning, stated they were at a tennis court and under the lights, she looked funny. Caller stated that her numbers are going down in right direction and in the process of resolving hopefully. Stated that she was really fit, lean, and active with no underlying health conditions. She stated that she was losing a pound a day and not trying or doing much but her weight kept going down a pound each day/ rapid weight loss without trying on 15Feb2021. Stated when it dipped to 105 all the way down to 102, she thought what is going on (reporters question). Stated she was not nauseous anymore, she was back to 105 lbs and it was an nauseous; underlying constant level of nausea, like anxiety tummy where you can't eat low level nausea, no appetite, unable to eat much on 15Feb2021. She doesn't recall ever having mono but had a mono type feeling, where she was tired and nauseous. Stated she was usually like the energizer bunny. Stated she couldn't get out of bed, she was over the top tired and fatigued, elevated bilirubin and liver enzymes on 15Feb2021. Caller stated that she was not afraid to get Covid but she doesn't know the long term side effects. Stated she believed in Science/ Caller stated that she is really healthy, eats mostly vegetarian diet, with a small amount of fish, has a healthy clean diet and lifestyle, no underlying health issues. The patient underwent lab tests and procedures which included alanine aminotransferase was 16 iu/l, aspartate aminotransferase was 22 ul, alkaline phosphatase was 57 iu/l, bilirubin total was 0.6 mg/dl on an unspecified date in Oct2020 and Covid-19 test was negative on 20Jan2021. Caller stated that she went in to the doctor and was establishing herself as a new patient, so she went to him and Alanine aminotransferase was 1726h iu/l, aspartate aminotransferase was 1348h ul, alkaline phosphatase was 198h iu/l, bilirubin total was 8.2h mg/dl (her liver and Bilirubin enzymes were off the chart and in danger zone), blood work showed her liver and bilirubin enzymes were off the chart on 15Feb2021. she had been to doctor every week and she was doing blood work weekly. She stated that she had an ultrasound of her abdomen, because of her bilirubin, they thought maybe gall stones, cancer, masses, tumors, liver. Stated they also did an in-depth CT scan (computerised tomogram) and MRCP (Magnetic resonance cholangiopancreatography) were negative on 17 Feb2021. Thursday 25Feb2021 she was negative for anything in her stomach, abdomen, liver, and kidneys. She is going to see the GI doctor weekly for blood work, states she just went yesterday but no results yet. On an unspecified date, labs for her liver were normal, ultrasound abdomen was negative and body lost 8lbs. It was reported that she was pro-vaccine and super supportive and wanted to travel when things open up, wants herd immunity. Caller stated two weeks after her first vaccine, she started experiencing her adverse reaction. Stated she was not looking for the sore arm usual reactions like most people had. Caller stated that she had regular labs with her previous doctor on Oct2020. She states she wants to list those for comparison to her adverse event levels. Caller asked where she can find the more serious adverse reactions online for otherwise healthy people (reporters question). Outcome of events Nauseous; underlying constant level of nausea, like anxiety tummy where you can't eat low level nausea, no appetite, unable to eat much and Fatigue were recovered on 12Mar2021. Patient did not visited to emergency room. Outcome of events the Covid vaccine her labs for her liver were normal and 2 weeks after taking 1st dose, they are not normal and Elevated Bilirubin and Liver Enzymes were unknown while events Jaundice and Rapid Weight Loss without Trying were recovering.  No follow up attempts are possible. No further information is expected.