Age: 30.0
Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Infertility, Lichen planus, Maternal exposure before pregnancy, SARS-CoV-2 test
Clinical narrative: Maternal exposure before pregnancy; Lichen planus on vagina which is now causing infertility; Lichen planus on vagina which is now causing infertility; This spontaneous prospective pregnancy case was reported by a patient and describes the occurrence of LICHEN PLANUS (Lichen planus on vagina which is now causing infertility), INFERTILITY (Lichen planus on vagina which is now causing infertility) and MATERNAL EXPOSURE BEFORE PREGNANCY (Maternal exposure before pregnancy) in a 30-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis.    Co-suspect product included non-company product TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) for COVID-19 prophylaxis.    No Medical History information was reported.   On 09-Apr-2021 at 1:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 07-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 20-Nov-2021 at 1:00 PM, the patient received third dose of TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) (unknown route) 1 dosage form. The patient's last menstrual period was on 22-Oct-2021 and the estimated date of delivery was 28-Jul-2022. On 07-Dec-2022, the patient experienced LICHEN PLANUS (Lichen planus on vagina which is now causing infertility). 07-Dec-2022, the patient experienced INFERTILITY (Lichen planus on vagina which is now causing infertility). On an unknown date, the patient experienced MATERNAL EXPOSURE BEFORE PREGNANCY (Maternal exposure before pregnancy). The patient received mRNA-1273 (Moderna COVID-19 Vaccine) during pregnancy and TOZINAMERAN (PFIZER BIONTECH COVID-19 VACCINE) beginning around the  fourth week of the pregnancy.  At the time of the report, LICHEN PLANUS (Lichen planus on vagina which is now causing infertility) and INFERTILITY (Lichen planus on vagina which is now causing infertility) had not resolved and MATERNAL EXPOSURE BEFORE PREGNANCY (Maternal exposure before pregnancy) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, SARS-CoV-2 test: Negative.   No concomitant and treatment medications were reported. Device date was reported as 11-Jan-2023.  Company comment: This spontaneous case concerns a 30-year-old female patient with no reported medical history, who experienced the unexpected non-serious events of lichen planus and infertility around 7 months after the second dose of mRNA-1273 Vaccine. Additionally, maternal exposure before pregnancy was also noted in the case. Patient received first 2 doses of Moderna vaccine and third dose was from Pfizer, which the patient received around the fourth week of pregnancy. The events of lichen planus and infertility occurred around 17 days post Pfizer vaccine administration. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Reporter's Comments: This spontaneous case concerns a 30-year-old female patient with no reported medical history, who experienced the unexpected non-serious events of lichen planus and infertility around 7 months after the second dose of mRNA-1273 Vaccine. Additionally, maternal exposure before pregnancy was also noted in the case. Patient received first 2 doses of Moderna vaccine and third dose was from Pfizer, which the patient received around the fourth week of pregnancy. The events of lichen planus and infertility occurred around 17 days post Pfizer vaccine administration. The benefit-risk relationship of mRNA-1273 is not affected by this report.