Age: 52.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: COVID-19, Neurological examination, SARS-CoV-2 test, Vaccination failure
Clinical narrative: extreme fatigue; around arms and seeming on nerves of arms uticaria; extreme itching; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 52-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 23Aug2021 as dose 3 (booster), single (Lot number: FA7485) at the age of 52 years intramuscular, in left deltoid for covid-19 immunization. The patient's relevant medical history included: "Migraine" (unspecified if ongoing);  (unspecified if ongoing), notes: "allergies" (unspecified if ongoing), notes: allergies; "tonsillectomy" (unspecified if ongoing); "adenoidectomy" (unspecified if ongoing); "hyper mobility" (unspecified if ongoing), notes: hyper mobility; "Known allergies: penicillin" (unspecified if ongoing); "Known allergies: Nuts, tree nuts, peanuts" (unspecified if ongoing), notes: Known allergies: Nuts, tree nuts, peanuts; "Late term food allergies", start date: 2012 (unspecified if ongoing), notes: onset date: 2012, 2013, 2015, increase in prednisone for food reactions (avoid); "Environmental allergies" (unspecified if ongoing). Concomitant medication(s) included: AIMOVIG taken for migraine, start date: Oct2017 (ongoing); ALLEGRA oral taken for hypersensitivity, start date: 2008 (ongoing). Past drug history included: Capsaicin, reaction(s): "Known allergies: Capsaicin", notes: Known allergies: Capsaicin. Vaccination history included: BNT162b2 (Dose: 1, Date: 22Feb2021 , Anatomical site: Left deltoid, ROA: Intramuscular, Lot: EL9266), administration date: 22Feb2021, when the patient was 51-year-old, for COVID-19 Immunization; BNT162b2 (Dose: 2, Date: 15Mar2021, Anatomical site: Left Deltoid, ROA: Intramuscular, Lot: EN6204), administration date: 15Mar2021, when the patient was 51-year-old, for COVID-19 Immunization; shingrex (Shingrex, dose:1), administration date: 23Nov2020; prevnar 13, administration date: 12Dec2019; shingrex (Shingrex H2), administration date: 21Jan2021. The following information was reported: URTICARIA (disability) with onset 2021, outcome "not recovered", described as "around arms and seeming on nerves of arms uticaria"; PRURITUS (disability) with onset 2021, outcome "not recovered", described as "extreme itching"; FATIGUE (disability), outcome "not recovered", described as "extreme fatigue". The event "extreme fatigue" required physician office visit. The events "around arms and seeming on nerves of arms uticaria" and "extreme itching" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Neurological examination: (unspecified date) 70 to 140, notes: Continue with Aimovig add nyrtec; SARS-CoV-2 test: (Jun2022) Negative, notes: COVID test type post vaccination=Nasal Swab; (16Jun2022) Pending, notes: Pending. Therapeutic measures were taken as a result of urticaria, pruritus, fatigue. Clinical course: Since 11Mar2021, 3 days prior to 2nd shot given at 15Mar2021 withheld Hospital around arms and seeming on nerves of arms urticaria and extreme itching that in Jun2022 is still here. If COVID prior vaccination: No; If COVID tested post vaccination: Yes. Also had weekly testing re that question. All negative except single binax at home positive 01Jan2022. Negative which tested by school. Use of medications that suppress immune system: for allergies to food not taken. Food allergies med allergen are avoided. Epi-pen. Test: Dermatologist  urgent care. Prescribed steroid topicals Betamethasone. Urticaria (on upper nerve path way and bruising) onset date: 14Mar2021. Treatment included multiple allergy meds, steroids, bandages to avoid infections, unknown effects thus test aid many with Rx topicals. Fatigue (Extreme) Failure of medication efficacy onset date: 25Feb2021. The patient believes the onset of photos which led to urticaria are the best manner to demonstrate the changes which occurred between shots 1 and 2. Due   the patient have seen needed specialists and cont. take care. Hives. extreme fatigue (this may have begun on date of 1st injection but it is still with her and is not improving without treatment), weird diet changes, excessive environmental sensitivity (smells reaction to chemicals which are benign agents in OTC products - mouth, toothpaste), Dental visit - 29Jun2022 to complete repair it was noted that gums seemed inflamed to level requiring rescheduling. Original signature on photocopy as events occurred at dentist 29Jun2022 delaying completion of treatment. No follow-up attempts are possible. No further information is expected.