Age: 11.0
Sex: F
Vaccine: HPV4
Symptoms: Dizziness, Dizziness postural, Loss of personal independence in daily activities, Postural orthostatic tachycardia syndrome, Visual impairment
Clinical narrative: autoimmune injuries / autoimmune disorder; Postural Tachycardia Syndrome/ severe dizziness upon standing, reading, and walking/ vision problems / autonomic injuries / neurologic injuries; Information was received from a lawyer regarding a case in litigation and refers to an adolescent (reported as adult, discrepant information) female patient (pt) (exact age not provided). Her medical history, concurrent conditions and concomitant therapies were not provided. On 22-MAY-2020, at the age of 11 years old, the pt was vaccinated with the first dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot # and expiration date were not provided) as recommended by physician, with her mother's consent, for prophylaxis (also reported as touted as safe and effective for preventing cervical cancer.) On 06-JAN-2021, at the age of 12 years old, she was vaccinated with the second dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot # and expiration date were not provided). That was also the last dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL). On an unknown date in 2021, after the second quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, the pt began to experience symptoms of severe dizziness upon standing, reading, and walking. As these symptoms continued, she also began to experience vision problems. On an unknown day in February 2023, the pt was diagnosed with Postural Tachycardia Syndrome. As the months progressed, so did the pt's injuries. She was seen by multiple physicians and specialists for her complaints which at that time included: dizziness upon standing, reading, and walking; and vision problems. The pt or her mother did not know and had no reason to know that the symptoms she was experiencing were caused by quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL), as no information to the contrary was given to her by her medical providers. It was not until late 2021 that she began to suspect that quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine was the cause of her symptoms and injuries. As a result of her post- quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt was unable to engage in activities that a normal young person would enjoy. Post- quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) injections, she was required to make more than the typical physicians visits to maintain her health. Additionally, she had to be more careful before committing herself to typical daily and social activities. Based upon her chronic and severe post- quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt was diagnosed with various medical conditions, including but not limited to, Postural Tachycardia Syndrome. The pt contended that her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological, injuries, including but not limited to Postural Tachycardia Syndrome, as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which are alleged herein and all of which were caused by quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. As a proximate result quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL), the pt suffered and continued to suffer severe and permanent physical injuries, and associated symptomology and suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to at that time being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) -induced injuries, the pt suffered and continues to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity and she would continue to incur these losses and expenses in the future. The outcome of the events was considered to be not recovered.  The reporter considered the events to be related to quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL).  Upon internal review, the event of autoimmune disorder was determined to be medically significant.  The reporter considered all events to be disabling.