Sex: M
Vaccine: COVID19-2
Symptoms: Allodynia, Hyperaesthesia, Investigation, Pain, Peripheral sensory neuropathy
Clinical narrative: painful thoracic sensory polyneuropathy/right lower thoracic/upper lumbar spine/spread bilaterally to pan-thoracic paraspinal area/along dermatomes to involve the area over the rib cage bilaterally; painful thoracic sensory polyneuropathy/right lower thoracic/upper lumbar spine/spread bilaterally to pan-thoracic paraspinal area/along dermatomes to involve the area over the rib cage bilaterally; severe tactile allodynia/hyperesthesia (up to 7/10)/excruciating allodynia which evoked images of being stabbed with a red-hot knife; hyperesthesia (up to 7/10)/slightest tactile stimulus such as shirt sliding over the skin of the torso produced severe burning pain; severe burning pain; This is a spontaneous report received from a non-contactable reporter(s) (Physician). The reporter is the patient.  A 63-year-old male patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 15Nov2022 at 09:30 as dose 4 (booster), single (Lot number: GJ6742), in left arm for covid-19 immunisation. The patient's relevant medical history included: "pre-existing peripheral neuropathy" (unspecified if ongoing), notes: pre-existing peripheral neuropathy flared prior to vaccine; "viral respiratory infections" (unspecified if ongoing), notes: does get much milder and shorter-lived cutaneous hyperesthesia during viral respiratory infections. The patient's concomitant medications were not reported. Vaccination history included: Covid-19 vaccine (DOSE 1, SINGLE), for COVID-19 immunization; Covid-19 vaccine (DOSE 2, SINGLE), for COVID-19 immunization; Covid-19 vaccine (DOSE 3 (BOOSTER), SINGLE), for COVID-19 immunization. The following information was reported: HYPERAESTHESIA (non-serious) with onset Nov2022, 1 week after the suspect product(s) administration, outcome "recovered", described as "hyperesthesia (up to 7/10)/slightest tactile stimulus such as shirt sliding over the skin of the torso produced severe burning pain"; PERIPHERAL SENSORY NEUROPATHY (non-serious), THORACIC RADICULOPATHY (non-serious) all with onset Nov2022, latency 1 week after the suspect product(s) administration, outcome "recovered" and all described as "painful thoracic sensory polyneuropathy/right lower thoracic/upper lumbar spine/spread bilaterally to pan-thoracic paraspinal area/along dermatomes to involve the area over the rib cage bilaterally"; PAIN (non-serious) with onset Nov2022, 1 week after the suspect product(s) administration, outcome "recovered", described as "severe burning pain"; ALLODYNIA (non-serious) with onset Nov2022, 1 week after the suspect product(s) administration, outcome "recovered", described as "severe tactile allodynia/hyperesthesia (up to 7/10)/excruciating allodynia which evoked images of being stabbed with a red-hot knife". Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were not taken as a result of peripheral sensory neuropathy, thoracic radiculopathy, allodynia, hyperaesthesia, pain.  Additional information: One week after vaccination patient developed a painful thoracic sensory polyneuropathy characterized by severe tactile allodynia/hyperesthesia (up to 7/10). It commenced right lower thoracic/upper lumbar spine but then spread bilaterally to pan-thoracic paraspinal area and then along dermatomes to involve the area over the rib cage bilaterally. The slightest tactile stimulus such as shirt sliding over the skin of the torso produced severe burning pain. There were areas bilaterally over the lower rib cage which were the sites of excruciating allodynia which evoked images of being stabbed with a red-hot knife. The patient does get much milder and shorter-lived cutaneous hyperesthesia during viral respiratory infections and has a pre-existing peripheral neuropathy. The pre-existing peripheral neuropathy had flared prior to vaccine but the flare involved the left foot and was resolving at the time the adverse event occurred. The patient did not experienced COVID-19 prior to vaccination. A home COVID-19 test was negative post vaccination. No other vaccines in four weeks.   No follow-up attempts are possible. No further information is expected.