Sex: F
Vaccine: COVID19
Symptoms: Injection site movement impairment, Injection site warmth, Limb discomfort, Paraesthesia, Tracheal inflammation
Clinical narrative: esophagus and trachea closed; experienced some heavy breathing; some pins and needles sensation around her outer thigh, hip bone, liver, and abdomen; arm felt like someone took a brick and kept pounding it; arm had hardness; the area was hot, hard, and heated; couldn't swallow saliva; Couldn't raise arm over shoulder; tongue felt like it was numb; Couldn't walk or stand up straight; A spontaneous report was received from a healthcare professional (HCP) concerning a 65-year-old, female patient who received Moderna's COVID-19 vaccine (mRNA-1273) and experienced esophagus and trachea closing/tracheal inflammation, heavy breathing/dyspnea, pins and needle sensation around her outer thigh, hip bone, liver and abdomen/paraesthesia, arm felt like someone took a brick and kept pounding it/limb discomfort, arm had hardness/injection site induration, area was hot and heated/injection site warmth, couldn't swallow saliva/dysphagia, couldn't raise arm over shoulder/injection site movement impairment, tongue felt like it was numb/hypoaesthesia oral, and couldn't walk or stand up straight/gait inability.  The patient's medical history was not provided.  Concomitant medication history was not provided.  On 03 FEB 2021, one day prior to the onset of the events, the patient received their first of two doses of mRNA-1273 (lot number: 043L20A) intramuscularly in the right arm for prophylaxis of COVID-19 infection.  On 04 FEB 2021, the patient experienced her esophagus and trachea closing.  She had some heavy breathing along with pins and needle sensation around her outer thigh, hip bone, liver and abdomen.  She stated that her arm felt like someone took a brick and kept pounding it.  Her arm had hardness and she couldn't raise it over her shoulder.  The area of her arm was hot, hard and heated.  The patient couldn't swallow her saliva, couldn't walk or stand up straight and her tongue felt like it was numb and stretched out.  An ambulance was called, and she was taken to the hospital.  She stated that she had never had such a reaction to a vaccine before.  She stated that since the event, her memory has been affected.  Treatments of these events included saline solution, a medication for relaxing and pain, and oxygen.  Action taken with mRNA-1273 in response to the events was not reported.  The outcome of the events, esophagus and trachea closing/tracheal inflammation, heavy breathing/dyspnea, pins and needles sensation around her outer thigh, hip bone, liver and abdomen/paraesthesia, arm felt like someone took a brick and kept pounding it/limb discomfort, arm had hardness/injection site induration, area was hot, and heated/injection site warmth, couldn't swallow saliva/dysphagia, couldn't raise arm over shoulder/injection site movement impairment, tongue felt like it was numb/hypoaesthesia oral, and couldn't walk or stand up straight/gait inability were unknown.; Reporter's Comments: Very limited information regarding this events has been provided at this time.  Further information has been requested.