Age: 71.0
Sex: M
Vaccine: COVID19
Symptoms: Endoscopy, Endoscopy small intestine, Exocrine pancreatic function test
Clinical narrative: Bad chronic liquid diarrhea 8 to 10 times a day; This spontaneous case was reported by a patient and describes the occurrence of DIARRHOEA (Bad chronic liquid diarrhea 8 to 10 times a day) in a 71-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 067F21A, 024M20A and 010A21A) for COVID-19 vaccination.     Patient had no allergies to food, medications and other products. Patient did not test positive for Covid-19 diagnosis. Patient did not receive other manufacturer vaccine one month prior to receiving Moderna Covid-19 vaccine.  Concurrent medical conditions included Migraine (40 years ago, no changes observed recently). Concomitant products included SUMATRIPTAN for Migraine.   On 14-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 21-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 12-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Nov-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced DIARRHOEA (Bad chronic liquid diarrhea 8 to 10 times a day). The patient was treated with LOPERAMIDE HYDROCHLORIDE (IMODIUM) at a dose of Imodium for 4 months; CHOLESTYRAMINE at a dose of UNK, qid; CIPROFLOXACIN HCL at a dose of 500 milligram; METRONIDAZOLE at a dose of 250 milligram three times a day; PROBIOTICS NOS at an unspecified dose and frequency; ATROPINE SULFATE, DIPHENOXYLATE HYDROCHLORIDE (DIPHENOXYLATE/ATROPINE) at an unspecified dose and frequency and LEVOTHYROXINE SODIUM (SYNTHROID) at a dose of Synthroid for 2 months. At the time of the report, DIARRHOEA (Bad chronic liquid diarrhea 8 to 10 times a day) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Allergy test: nothing abnormal found nothing abnormal found (food allergy panel). On an unknown date, Biopsy: nothing abnormal found nothing abnormal found. (9 biopsies performed).. On an unknown date, Blood test: nothing abnormal found nothing abnormal found. On an unknown date, Colonoscopy: nothing abnormal found nothing abnormal found. On an unknown date, Endoscopy: nothing abnormal found nothing abnormal found. On an unknown date, Endoscopy small intestine: nothing abnormal found nothing abnormal found. On an unknown date, Exocrine pancreatic function test: nothing abnormal found nothing abnormal found.         Patient reported that received 3 vaccines on deltoid muscle upper arm.  Patient received booster dose. Patient reported that episodes always appeared 20 minutes after eating anything. Patient sometimes stayed 3 days without eating to avoid having any depositions. Patient sought medical care for the adverse event. It was reported that symptoms were  worsened with all the medication doctors gave to patient except for Imodium as this medication was suspended by doctors because had opioid on his formulation. .