Sex: F
Vaccine: RAB
Symptoms: Asthenia, Chest pain, Erythema, Hypoaesthesia, Injection site erythema
Clinical narrative: vague aches; reddish color to her cheeks; Serum sickness-like reaction; malaise; fever 101 at night; hands and legs go numb all night; reactions to the injection site with redness areas around patient arms; weakness; Initial information regarding an unsolicited valid non-serious case was received from a Physician via Agency (Reference number- 00357713) and transmitted to Sanofi on 12-Nov-2020.  This case involves a 43 year old female patient who experienced serum sickness-like reaction, malaise, fever 101 at night (pyrexia), hands and legs go numb all night (hypoaesthesia), vague aches (pain), reactions to the injection site with redness areas around patient arms (injection site erythema) and weakness (asthenia) and occasionally had reddish color to her cheeks (Erythema), while she received RABIES (HDC) VACCINE [IMOVAX RABIES].  The patient's medical history, past medical treatment, vaccination, concomitant medication and family history were not provided.  On 22-Oct-2020, the patient that was bitten on the right cheek.  On 22-Oct-2020, the patient received a first dose of suspect RABIES (HDC) VACCINE standard dose and standard strength (lot number: T18813M) via unknown route in an unknown site for post exposure immunization.   On an unknown date, she received a second dose of the RABIES (HDC) VACCINE standard dose and standard strength (lot number: T18813M) via unknown route in an unknown site.   On an unknown date, she received a third dose of the RABIES (HDC) VACCINE standard dose and standard strength (lot number: T18813M) via unknown route in an unknown site.  On 05-Nov-2020, she received a fourth dose of the RABIES (HDC) VACCINE standard dose and standard strength (lot number: T18813M) via unknown route in right and left arms  On an unknown date, patient states that she had serum sickness like reactions (serum sickness-like reaction) (like it was stated in the package insert). Patient also states that her symptoms became more pronounced after each dose and the symptoms began two or three days after each dose.   On an unknown date, the patient presented with vague aches (pain), fever 101 at night (pyrexia), weakness (asthenia), malaise, aches and hurts all over (pain) occasional reddish color to her cheeks (Erythema), and her hands and legs go numb all night (hypoaesthesia). Patient mentioned she had local reactions to the injection site with redness areas around her arms (injection site erythema).  On 05-Nov-2020, she received a fourth dose of the RABIES (HDC) VACCINE standard dose and standard  patient stated that the last injection they gave her half the dose in the left arm and half the dose in the right arm, she did not have any reaction and physician wanted to know how long these symptoms will persist as the package insert does not say anything about that.  Patient stated that she had completed four doses and knows the package insert recommends five.  Laboratory test were not reported.    Patient recieved IMMUNOGLOBULIN [IMMUNOGLOBULINS NOS] as a corrective treatment.  Event outcome was reported as Unknown for all the events.