Age: 47.0
Sex: F
Vaccine: COVID19
Symptoms: Anxiety, Blood magnesium, Blood pressure measurement, Blood thyroid stimulating hormone, Chest discomfort
Clinical narrative: felt like an anxiety attack; Tightness in chest\baby elephant sitting on your chest; Dyspnea/shortness of breath/pain with breathing (yes/no): yes (oxygen 100% on room air); racing heart/Tachycardia - heart rate 100 bpm/ heart rate of 115; high blood pressure after booster shot/taken to hospital by ambulance with high blood pressure/blood pressure was 193/93 in ambulance/High blood pressure 150/76; This spontaneous case was reported by a consumer and describes the occurrence of HYPERTENSION (high blood pressure after booster shot/taken to hospital by ambulance with high blood pressure/blood pressure was 193/93 in ambulance/High blood pressure 150/76), TACHYCARDIA (racing heart/Tachycardia - heart rate 100 bpm/ heart rate of 115), ANXIETY (felt like an anxiety attack), CHEST DISCOMFORT (Tightness in chest\baby elephant sitting on your chest) and DYSPNOEA (Dyspnea/shortness of breath/pain with breathing (yes/no): yes (oxygen 100% on room air)) in a 47-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 027H21B, 010M20A and 002B21A) for COVID-19 vaccination.     Concurrent medical conditions included Environmental allergy (started allergy shot), Drug allergy (Codeine), Drug allergy (fentanyl- itching, welts), Blood pressure high (Started more than 10 years ago and recent change in status was worsening.), Stomach discomfort and Sleep difficult. Concomitant products included LISINOPRIL for Blood pressure high, ZOLPIDEM for Sleep difficult, PLECANATIDE (TRULANCE) for Stomach discomfort, SIMVASTATIN for an unknown indication.   On 08-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 milliliter. On 05-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to .5 milliliter. On 09-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 09-Dec-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced HYPERTENSION (high blood pressure after booster shot/taken to hospital by ambulance with high blood pressure/blood pressure was 193/93 in ambulance/High blood pressure 150/76). On 22-Mar-2022, the patient experienced TACHYCARDIA (racing heart/Tachycardia - heart rate 100 bpm/ heart rate of 115). On an unknown date, the patient experienced ANXIETY (felt like an anxiety attack), CHEST DISCOMFORT (Tightness in chest\baby elephant sitting on your chest) and DYSPNOEA (Dyspnea/shortness of breath/pain with breathing (yes/no): yes (oxygen 100% on room air)). The patient was treated with METOPROLOL TARTRATE in March 2022 at a dose of 25 milligram twice a day. At the time of the report, HYPERTENSION (high blood pressure after booster shot/taken to hospital by ambulance with high blood pressure/blood pressure was 193/93 in ambulance/High blood pressure 150/76) and TACHYCARDIA (racing heart/Tachycardia - heart rate 100 bpm/ heart rate of 115) had not resolved and ANXIETY (felt like an anxiety attack), CHEST DISCOMFORT (Tightness in chest\baby elephant sitting on your chest) and DYSPNOEA (Dyspnea/shortness of breath/pain with breathing (yes/no): yes (oxygen 100% on room air)) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Blood pressure measurement: 135/85 blood pressure reading was 135/85. In 2021, Heart rate: high (High) heart rate was high. In December 2021, Blood pressure measurement: 193/98 blood pressure was 193/98. In December 2021, Heart rate: 115 bp 115 bp. In December 2021, Oxygen saturation: 100% oxygen level of 100% on room air. In 2022, Blood magnesium: unknown Unknown. In 2022, Blood pressure measurement: 150/76 (High) High blood pressure 150/76. In 2022, Blood thyroid stimulating hormone: unknown Unknown. In 2022, Electrocardiogram: normal (normal) Normal. In 2022, Full blood count: unknown Unknown. In 2022, Heart rate: 100 bpm heart rate 100 bpm. In 2022, Metabolic function test: unknown Unknown. In 2022, Troponin: 0.2 mg/ml 0.2 mg/mL.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered HYPERTENSION (high blood pressure after booster shot/taken to hospital by ambulance with high blood pressure/blood pressure was 193/93 in ambulance/High blood pressure 150/76) and TACHYCARDIA (racing heart/Tachycardia - heart rate 100 bpm/ heart rate of 115) to be related. No further causality assessments were provided for ANXIETY (felt like an anxiety attack), CHEST DISCOMFORT (Tightness in chest\baby elephant sitting on your chest) and DYSPNOEA (Dyspnea/shortness of breath/pain with breathing (yes/no): yes (oxygen 100% on room air)).    It was reported that the patient received the Moderna COVID-19 vaccine primary series and booster. After receiving the 2nd dose, the patient had high blood pressure. Noticed when the patient went to the dentist in Mar-2021 and Apr-2021 for oral surgery. The patient heart rate was high and blood pressure reading was 135/85 and climbing.  After receiving the booster dose in Dec-2021, the patient ife taken to the hospital via ambulance with a racing heart and high blood pressure. When the ambulance arrived, her blood pressure was 193/98, heart rate of 115 bpm, and oxygen level of 100% on room air.   It was reported that in the ambulance, the patient was given a shot that leveled her heart. The was not admitted to the hospital; she was treated in the ambulance, prescribed metoprolol tartrate 25mg twice a day, and referred to the cardiologist because the patient's lab values were perfect and nothing was wrong.   It was further mentioned that every time patient got her booster shot, she had high blood pressure after each booster.   The patient also started allergy shots after receiving the vaccine for environmental allergies so thought the symptoms were due to the allergy shots, but later the patient suspect it was the Moderna COVID-19 vaccine.  The patient was never tested positive for COVID-19. The patient to seek medical care ER, office visit (cardiologist) on 05-Apr-2022 for High blood pressure 150/76 and heart rate 100 bpm. The patient never experienced a similar event in the past. The conditioned was ongoing and worsened.  There were no diagnosis of myocarditis or pericarditis.  There were no Syncope and Myocardial edema/cardiomyopathy/pericardial effusion/infective pericardial effusion/pericardial effusion malignant.   This case was linked to MOD-2022-531902, MOD-2022-531876 (Patient Link).