Sex: F
Vaccine: MMR, MMR, VARZOS
Symptoms: Condition aggravated, Fatigue, Lymphadenopathy, Odynophagia, Therapeutic response decreased
Clinical narrative: Swollen Lymph Nodes in Neck; Painful Swallowing; Fatigue; Swollen Lymph Nodes in Neck; Condition aggravated; Fatigue aggravated; low titer of 2 of 3 components in MMR; This case was reported by a consumer via call center representative and described the occurrence of lymphadenopathy cervical in a female patient who received Herpes zoster (Shingrix) (batch number unknown, expiry date 2020) for prophylaxis.   Co-suspect products included MMR (MMR vaccine) for prophylaxis and MMR (MMR vaccine) for prophylaxis.   In April 2019, the patient received the 1st dose of Shingrix (intramuscular) .5 ml. On an unknown date, the patient received MMR vaccine. In May 2019, the patient received MMR vaccine (intramuscular) .5 ml. On an unknown date, 2 days after receiving Shingrix and not applicable after receiving MMR vaccine and MMR vaccine, the patient experienced lymphadenopathy cervical, swallowing painful, fatigue, lymphadenopathy cervical, condition aggravated, fatigue aggravated and therapeutic response decreased. The patient was treated with non-drug therapy (Heat Therapy). On an unknown date, the outcome of the lymphadenopathy cervical, swallowing painful, lymphadenopathy cervical and fatigue aggravated were not recovered/not resolved and the outcome of the fatigue, condition aggravated and therapeutic response decreased were unknown.   It was unknown if the reporter considered the lymphadenopathy cervical, swallowing painful and fatigue to be related to Shingrix. It was unknown if the reporter considered the therapeutic response decreased to be related to MMR vaccine. It was unknown if the reporter considered the lymphadenopathy cervical, condition aggravated and fatigue aggravated to be related to MMR vaccine.  Additional details were provided as follows: The age at vaccination was not reported. On an unknown date, the patient received MMR vaccine. Approximately 3 weeks ago (from the reporting date), the patient received the dose of Shingrix in right arm. The following week, she received booster MMR vaccine in left arm. Lot number was unknown but the patient remember Shingrix expiry date as year 2020. The Booster dose of MMR vaccine was administered due to low titer of 2 of 3 components in MMR, this led to therapeutic response decreased.  Roughly 2 days after receiving Shingrix vaccine, the patient complained of fatigue and swollen lymph node glands in neck. The patient reported that the swelling occurred intermittently. She felt okay in the morning, but not so well in afternoon or evening. The patient also experienced pain when swallowing due to the pain from swollen lymph nodes in neck.  After 1 day of receiving booster MMR vaccine, the events fatigue and swollen lymph node glands in neck were worsened.  The physician recommended her to drink a lot of hot liquids and apply heat for relief. The patient believed this can also be attributed to weather, this included an unusual amount of rain and also lots of pollination. She termed this as triple whammy (Shingrix, MMR, and allergy season). The patient did not consent to follow-up due to feeling like she would get someone in trouble. The patient did not want to receive follow-up.