Age: 74.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Hypersensitivity, Mouth swelling
Clinical narrative: Uvula was swollen; she had an allergic reaction; blood pressure went down; pulse went down; roof of her mouth swelled up; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 74 year-old female patient received bnt162b2 (BNT162B2), administration date 22Feb2021 (Lot number: EN6200, Expiration Date: 30Jul2021) at the age of 74 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "allergies to drugs" (unspecified if ongoing), notes: She pretty much knew she had a lot of allergies to drugs.; "iodine contrast dye allergy" (unspecified if ongoing); "respiratory arrest" (unspecified if ongoing); "allergic to different antibiotics" (unspecified if ongoing); "allergic to certain foods" (unspecified if ongoing); "allergic to the preservative in the flu vaccine" (unspecified if ongoing); "covid-19", start date: 25Apr2020 (unspecified if ongoing); "She cannot have sulfa drugs" (unspecified if ongoing), notes: She couldn't even administer Mucamist to her patients because of the sulfa in it.; "She can't take penicillin" (unspecified if ongoing). There were no concomitant medications. Vaccination history included: Bnt162b2 (1st dose, lot number EL8982, and expiration May2021.), administration date: 02Feb2021, when the patient was 74 years old, for COVID-19 Immunization, reaction(s): "She had the first Pfizer COVID vaccine on 02Feb 2021 and her mouth swelled up terribly". The following information was reported: ENLARGED UVULA (medically significant) with onset 22Feb2021, outcome "unknown", described as "Uvula was swollen"; HYPERSENSITIVITY (medically significant) with onset 22Feb2021, outcome "recovered" (2021), described as "she had an allergic reaction"; BLOOD PRESSURE DECREASED (medically significant) with onset 22Feb2021, outcome "recovered" (2021), described as "blood pressure went down"; HEART RATE DECREASED (medically significant) with onset 22Feb2021, outcome "recovered" (2021), described as "pulse went down"; MOUTH SWELLING (medically significant) with onset 22Feb2021, outcome "recovered" (2021), described as "roof of her mouth swelled up". The events "uvula was swollen", "she had an allergic reaction", "blood pressure went down", "pulse went down" and "roof of her mouth swelled up" were evaluated at the emergency room visit. The patient underwent the following laboratory tests and procedures: blood pressure measurement: (22Feb2021) went down; heart rate: (22Feb2021) went down. Therapeutic measures were taken as a result of enlarged uvula, blood pressure decreased, heart rate decreased, mouth swelling.  Clinical course: She had the first Pfizer COVID vaccine on 02Feb2021, and her mouth swelled up terribly. She took a Benadryl before. Then, she got her second COVID vaccine, and within 15 minutes she had an allergic reaction. Instead of how everything usually goes up in a reaction, everything went down. Her blood pressure went down, her pulse went down. She bottomed out. The roof of her mouth swelled up. This occurred within the 15 minutes. She pretty much knew she had a lot of allergies to drugs so they told her to get it done at the hospital. Within 15 minutes, she opened her mouth, and the doctor said the roof of her mouth was swelled. The doctor was sitting beside her. He told her to open her mouth, and her Uvula was swollen. They took her in a wheel chair to the Emergency room. They gave her a Benadryl shot, and an Epi shot. The patient is not going to get the booster. She had COVID 25Apr2020. She was still tired all the time since she had COVID virus. She sleeps a lot. She was also still more achy than normal. She is a very active female. She doesn't look her age at all. She does yoga and goes to the gym daily. She is still active.  Follow-up attempts are completed. No further information is expected.