Age: 77.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Platelet count, Platelet count decreased
Clinical narrative: Platelet count slowly dropped after the first vaccine; This spontaneous case was reported by a patient and describes the occurrence of PLATELET COUNT DECREASED (Platelet count slowly dropped after the first vaccine) in a 77-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 031L20A) for COVID-19 prophylaxis.     The patient's past medical history included Knee surgery NOS in May 2021. Concurrent medical conditions included Osteoarthritis (No recent change in condition status) since 1995, Hypertension (No recent change in condition status) since 1990, Blood cholesterol abnormal, Obesity ((BMI = 30)) and Sodium low. Concomitant products included EZETIMIBE, SIMVASTATIN (EZETIMIBE & SIMVASTATIN) for Blood cholesterol abnormal, AMLODIPINE and CARVEDILOL for Hypertension, SODIUM CHLORIDE for Sodium low.    On 28-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In 2021, the patient experienced PLATELET COUNT DECREASED (Platelet count slowly dropped after the first vaccine). At the time of the report, PLATELET COUNT DECREASED (Platelet count slowly dropped after the first vaccine) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Platelet count: Slowly dropped..     mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) dosing remained unchanged.       The patient did not experience a similar event in the past. The patient's platelet count slowly dropped after the first vaccine. No treatment details were provided. Allergies to medications, food, and other products were none. The patient not had ever been diagnosed with/ tested positive for COVID-19. Acute illnesses at the time of vaccination and up to one month before were none.   Company comment: This spontaneous case concerns a 77-year-old female patient, with relevant medical history of osteoarthritis, on Carvedilol for hypertension, who experienced the unexpected non-serious AESI of Platelet count decreased (reported as Platelet count slowly dropped after the first vaccine) after receiving the 1st dose of mRNA-1273 vaccine. The event occurred within the same year of vaccination. Clinical course and treatment details were not reported. The outcome of event was reported as not resolved. Concomitant Carvedilol could be considered as a confounder for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-589937, MOD-2022-589935 (Patient Link).; Sender's Comments: This spontaneous case concerns a 77-year-old female patient, with relevant medical history of osteoarthritis, on Carvedilol for hypertension, who experienced the unexpected non-serious AESI of Platelet count decreased (reported as Platelet count slowly dropped after the first vaccine) after receiving the 1st dose of mRNA-1273 vaccine. The event occurred within the same year of vaccination. Clinical course and treatment details were not reported. The outcome of event was reported as not resolved. Concomitant Carvedilol could be considered as a confounder for the event. The benefit-risk relationship of mRNA-1273 is not affected by this report.