Age: 28.0
Sex: M
Vaccine: HEPA, YF
Symptoms: Bacterial infection, Cardiac failure, Hypertension, Injection site reaction, Laboratory test abnormal
Clinical narrative: From initial information received on 18Oct04 from the pt regarding an adverse event occurring, it was reported that the 26 yr old male received a dose of YF Vax, lot number 0960560, expiration date 04Jun99; a dose of oral Typhoid vaccine, lot number 01508501A; and a dose of hep A vaccine, lot number 0764H, administered on 23Jan99. The routes and sites of administration were not reported. The pt was seen by a physician on 23Jan99 after developing a local reaction at the injection site. He had no shortness of breath and did not have an increased heart rate. His initial blood pressure reading was 230/120. Subsequent blood pressure readings were 230/120, 170/103, 166/109, 164/86, and 164/80. He was treated with Clonidine 0.2mg. The pt reported that he developed heart failure and kidney failure as well as severe hypertension. Per the pt, his physician were unable to determine the cause of these conditions. Reportedly, he did not recover from these events. From additional information received on 08Nov04 from the pt, it was reported that he will be seeing his cardiologist in two weeks. His recovery status was not reported. The adverse event coding has been updated from kidney disorder to kidney failure. From additional information  received on 21Dec04 from a military official, the reporter stated that he longer has access to the pt's records and can only provide information based on his recollections. The reporter also stated that what the pt reported to us on the form differs from teh documentation he has. Per the reporter, the pt received his first dose of YF Vax, a first dose of hep A vaccine and a dose of oral Typhoid vaccine on 23Jan99. That same day, the pt developed a local reaction consisting of a large blotch at the site of the YF Vax injection. The reporter explained that the physicians at the base are not treating physicians and pt's requiring medical intervention would be referred to a local ER. Per the reporter, this pt was not referred. In addition, the reporter clarified that the vaccine administrator reported by the pt did not administer the vaccines, but was in charge of the vaccine program. Approx one month after receiving the vaccines, the pt was deployed to a different state. There were no reports of any medical problems or events at that time. One and a half years later, in June 2000, the pt was deployed to another country. While there, two or three other members of his unit were diagnosed with Group B strep. Their diagnoses were confirmed with lab testing. The pt reported that he was also infected with strep, but this was not confirmed by any lab testing. It was during this time or shortly thereafter that the pt developed heart failure, kidney failure and hypertension. He was medically discharged from military duty in 2001 or 2002. It was also noted that the pt's blood pressure readings on the form are from 23Jan99, not 2004. Per the reporter, the pt's medical records were sent to retention and they are unavailable. No more information will be available for this case. No further information is anticipated, this case is considered closed.  From additional information received on 05Jan05 from the yellow fever work group meeting minutes, it was reported that the report number is 228178. No relevant additional information was provided for the adverse experience. This follow up information is not submitted to the health authorities.