Sex: F
Vaccine: PNC20, PNC20, PNC20
Symptoms: Injection site bruising, Injection site erythema, Injection site pain, Injection site pruritus, Injection site swelling
Clinical narrative: Drowsiness, Very sleepy; Terribly tired; Itching; arms changed color; it's not a small area, it's all of upper arm and around arm towards breast line; Blisters all over upper arm; Lump in my arm; arm arched; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 60-year-old female patient received pneumococcal 20-val conj vac (dipht CRM197 protein) (PREVNAR 20), in Jul2022 as dose number unknown, single (Batch/Lot number: unknown) for immunisation. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: BLISTER (non-serious) with onset Jul2022, outcome "unknown", described as "Blisters all over upper arm"; SOMNOLENCE (non-serious) with onset Jul2022, outcome "unknown", described as "Drowsiness, Very sleepy"; PRURITUS (non-serious) with onset Jul2022, outcome "recovering", described as "Itching"; LIMB MASS (non-serious) with onset Jul2022, outcome "unknown", described as "Lump in my arm"; FATIGUE (non-serious) with onset Jul2022, outcome "unknown", described as "Terribly tired"; LIMB DISCOMFORT (non-serious) with onset Jul2022, outcome "unknown", described as "arm arched"; SKIN DISCOLOURATION (non-serious) with onset Jul2022, outcome "unknown", described as "arms changed color; it's not a small area, it's all of upper arm and around arm towards breast line". The events "itching", "arms changed color; it's not a small area, it's all of upper arm and around arm towards breast line" and "blisters all over upper arm" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of pruritus, skin discolouration, blister.  Additional information: on last Thursday which was a week or so before 30Jul2022 (Jul2022), the patient was administered the Prevnar 20, Pneumonia vaccine and the first 2 days she did not have any noticeable side effect other than drowsiness, she was terribly tired by Saturday a week before 30Jul2022, she started developing itching and her arms changed color, she thought it was going to go away but on Wednesday she saw it's almost a week and her arm was getting worse so she contacted the pharmacy explained to them what she was experiencing and they told her if she wasn't getting better then would recommend she go to her doctor. Her doctor, on 29Jul2022, prescribed 1 percent Hydrocortisone and an antibiotic (Treatment) because it's not a small area, it's all of her upper arm and around her arm towards her breast line. The itching has not gone away and the blisters, there's blisters all over her upper arm so, she called to her pharmacist because her doctor was not open to say well the itching hasdsubsided a little but she had to apply the hydrocortisone to like every 2 hours for it be like at least tolerant and she thought maybe if I cover it, it would be better but the pharmacy said no do not cover it, you need to call Pfizer, there's a lump in her arm, her arm was terribly discolored. She was very sleepy and drowsy, her arm arched which she excepted because she had a jab but the sleepiness she never expected but she slept. Her doctor gave her the hydrocortisone to reduce itching because she told if she itch, if she scratch with fingers or anything then the skin will rupture but this discoloration was about 2 and a half inches wide and she would say about a foot going around her arms so, what's with the vaccine.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.