Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: Alopecia, Arthritis reactive, Interchange of vaccine products, Vaccination site pain, Vaccination site pruritus
Clinical narrative: Reactive arthritis/Deep pain inside both pelvic hip sockets/It ate my soft tissue bone and ate  my bone as well; I lost my hair too; Injection sites flare up with deep tissue thrombosis like itchy pain; INJECTION SITES FLARE UP WITH DEEP TISSUE THROMBOSIS LIKE ITCHY PAIN; Interchange of vaccine products; This spontaneous case was reported by a patient and describes the occurrence of ARTHRITIS REACTIVE (Reactive arthritis/Deep pain inside both pelvic hip sockets/It ate my soft tissue bone and ate  my bone as well) in a 62-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Salmonella (Bout of Salmonella) in 2014. Previously administered products included for COVID-19 vaccination: J & J Shot in 2021. Past adverse reactions to the above products included No adverse event with J & J Shot.    On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced ARTHRITIS REACTIVE (Reactive arthritis/Deep pain inside both pelvic hip sockets/It ate my soft tissue bone and ate  my bone as well) (seriousness criterion medically significant), ALOPECIA (I lost my hair too), VACCINATION SITE PAIN (Injection sites flare up with deep tissue thrombosis like itchy pain), VACCINATION SITE PRURITUS (INJECTION SITES FLARE UP WITH DEEP TISSUE THROMBOSIS LIKE ITCHY PAIN) and INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine products). At the time of the report, ARTHRITIS REACTIVE (Reactive arthritis/Deep pain inside both pelvic hip sockets/It ate my soft tissue bone and ate  my bone as well), ALOPECIA (I lost my hair too), VACCINATION SITE PAIN (Injection sites flare up with deep tissue thrombosis like itchy pain), VACCINATION SITE PRURITUS (INJECTION SITES FLARE UP WITH DEEP TISSUE THROMBOSIS LIKE ITCHY PAIN) and INTERCHANGE OF VACCINE PRODUCTS (Interchange of vaccine products) outcome was unknown.            No concomitant drug was provided by reporter. No treatment drug was provided by reporter.  Company Comment: This spontaneous case concerns a 62-year-old, female patient with medical history of salmonellosis who experienced the unexpected, serious (medically significant) adverse event of special interest Reactive arthritis which occurred on unknown interval after receiving the booster dose of mRNA-1273. Interchange of vaccine products is noted in the case as patient received Janssen COVID-19 vaccine as primary vaccination prior to mRNA-1273 administration. There was no adverse event reported after the previous COVID-19 vaccination. The event was further described as pain affecting the hip and shoulder joints. Symptoms have worsened in subsequent months with pain occurring daily and increasing severity leading to difficulty in ambulation and restricted movement. Patient reported similar symptoms described as bone pain seven years ago after a salmonella infection. The condition resolved and never recurred.  Diagnostic evaluation and treatment details were not reported in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.; Sender's Comments: This spontaneous case concerns a 62-year-old, female patient with medical history of salmonellosis who experienced the unexpected, serious (medically significant) adverse event of special interest Reactive arthritis which occurred on unknown interval after receiving the booster dose of mRNA-1273. Interchange of vaccine products is noted in the case as patient received Janssen COVID-19 vaccine as primary vaccination prior to mRNA-1273 administration. There was no adverse event reported after the previous COVID-19 vaccination. The event was further described as pain affecting the hip and shoulder joints. Symptoms have worsened in subsequent months with pain occurring daily and increasing severity leading to difficulty in ambulation and restricted movement. Patient reported similar symptoms described as bone pain seven years ago after a salmonella infection. The condition resolved and never recurred.  Diagnostic evaluation and treatment details were not reported in the case. The benefit-risk relationship of mRNA-1273 is not affected by this report.