Age: 69.0
Sex: M
Vaccine: COVID19, UNK, UNK, UNK
Symptoms: Asthenia, Lethargy, Mobility decreased
Clinical narrative: No energy to do anything; patient wok up feeling paralyzed; Patient had slight reactions of being lethargic for a couple of days after first dose/ became lethargic after fourth dose/ had extreme lethargy after fifth dose; This spontaneous case was reported by a patient and describes the occurrence of LETHARGY (Patient had slight reactions of being lethargic for a couple of days after first dose/ became lethargic after fourth dose/ had extreme lethargy after fifth dose), MOBILITY DECREASED (patient wok up feeling paralyzed) and ASTHENIA (No energy to do anything) in a 69-year-old male patient who received SPIKEVAX NOS (SPIKEVAX NOS) (batch nos. D9R21A, 064021A and 1361F22A) for COVID-19 prophylaxis.    Co-suspect products included non-company products FLUOXETINE HYDROCHLORIDE (PROZAC) for an unknown indication, ALPRAZOLAM tablet for Sleep disorder NOS and MODAFINIL for an unknown indication.    Concurrent medical conditions included Anxiety, Depression and Sleep disorder NOS.   On 01-Apr-2021, the patient received first dose of SPIKEVAX NOS (SPIKEVAX NOS) (unknown route) 1 dosage form. On 30-Apr-2022, received fourth dose of SPIKEVAX NOS (SPIKEVAX NOS) (unknown route) dosage was changed to 1 dosage form. On 30-Oct-2022, received fifth dose of SPIKEVAX NOS (SPIKEVAX NOS) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient started FLUOXETINE HYDROCHLORIDE (PROZAC) (unknown route) 80 milligram once a day, ALPRAZOLAM (unknown route) 1 milligram at bedtime and MODAFINIL (unknown route) 200 milligram once a day. In April 2021, the patient experienced LETHARGY (Patient had slight reactions of being lethargic for a couple of days after first dose/ became lethargic after fourth dose/ had extreme lethargy after fifth dose). In 2022, the patient experienced MOBILITY DECREASED (patient wok up feeling paralyzed). On an unknown date, the patient experienced ASTHENIA (No energy to do anything). At the time of the report, LETHARGY (Patient had slight reactions of being lethargic for a couple of days after first dose/ became lethargic after fourth dose/ had extreme lethargy after fifth dose), MOBILITY DECREASED (patient wok up feeling paralyzed) and ASTHENIA (No energy to do anything) outcome was unknown.   Concomitant medications were not reported. After receiving first dose, patient had slight reactions of being lethargic for a couple of days. After receiving fourth dose, patient became lethargic and was bed ridden for 5 months. The patient wok up feeling paralyzed. After receiving fifth dose, patient had extreme lethargy. No energy to do anything. The patient was in bed for 5 weeks. The patient stated that he had taken antidepressants and psychotropic drugs for anxiety and depression, and he believed that these medications increased his lethargy after the Moderna Covid-19 vaccine. The patient started taking Modafanil 200mg daily since his last Moderna Coviod-19 vaccine and was excited to see if he would not be as lethargic after his Spikevac vaccine. The patient received the RSV vaccine one week ago. The injections site to the RSV was in a deep tissue injection site and the injection site hurt a great deal. The patient also received the flu shot, Tetanus shot and Pneumococcal vaccine on the same date. The patient had extreme lethargy to the Pneumococcal vaccine only. No treatment medication reported.   This case was linked to MOD-2023-750774, MOD-2023-750747 (Patient Link).