Age: 1.5
Sex: M
Vaccine: DTP, HEP, HIBV
Symptoms: Drug toxicity, Hypersensitivity, Laboratory test abnormal, Nervous system disorder, Otitis media
Clinical narrative: An attorney reported the occurrence of mercury poisoning in a male child, now 7 years old, who was vaccinated with hep B vaccine recombiant (Engerix B) for prophylaxis. This report was received as part of litigation proceedings and has not been verified by a physician or other health care professional. The subject's medical history, concurrent conditions, and concurrent medications were not reported. The subject received injections of Engerix B "on or about" 6/1/95 and 7/18/95. Lot numbers were not reported. The subject also received Tri-Immunol 7/18/95, 9/19/95, 11/24/95 and 10/3/96; and Hib Titer 7/18/95, 9/19/95, 11/29/95 and 8/96. The subject's attorney alleged that "As a result of the mercury in the thimerosal-tainted vaccinations received during these developmental years, the Minor Plaintiff now suffers and in the future will continue to suffer, from the toxic neurological effects of mercury poisoning." This report of mercury poisoning is considered medically serious (OMIC). Follow up on 12/08/03: "The most recent info received on 11/21/03, did not provide the outcome of the alleged event.  This report of mercury poisoning is considered to be medically serious by GSK. (OMIC)" Follow up: Following the report immunizations with Engerix B, the patient experienced acute sinusitis, sulfa allergy, chronic adenotonsillitis and chronic secretory otitis media, and underwent tonsillectoy, adenoidecomy, and bilateral typanostomy. These were not reported as adverse events due to vaccine administration, but were found during the course of review of the patient's medical records.Therefore, they are not lissted as adverse events. The most recent informaiton, received on 13April2004, did not provide the outcoe of the alleged event. This report is mercury poisoning is considered to be medicaly serious by GlaxoSmithKline. Follow up on 05/17/04 states: "The following informationw as obtained via medical records. A mother gave birth to an eight pound, six ounce male infant, who was 20.5 inches in length on 05/17/95.  The mother had a history of gestational diabetes controlled by diet. She had a history of condyloma. She delivered a normal infant via vaginal delivery with forceps assisted rotation. Upon delivery, the infant's color was dusky. He was given blow by oxygen for color. The infant Apgar scores at one and five minutes were 8/9." On 20MAY1995, when the infant was three days old, his total bilirubin was 11.5 mg%. His direct bilirubin was within normal limits. By 22MAY1995, his total biliruin had decreased to 7.9 mg%. Medical hx significant for multiple ear infections from three months to two years of age. The child began walsing at 11-12 months of age. The child began speaking at 11 months of age,then stopped when he was 18 months of age. In March 1998, the child was diagnosed with autism, developmental delay and nutritional deficiencies. He was placed on casein free/gluten free diet. He began receiving speech therapy in March 1998. Behaviors or actions noted by his mother prior to and as of 29APR1998 (date of onset not provided), when her child was almost three years of age, included teeth grinding, short attention spain, easily distracted by noise, dehydration and poor learning through verbal or visual instruction, does not play well with other children, repeats what he hears, points to objects that he wants, has a hard time falling asleep at nght, does nto make eye contact, throws temperature tantrums, hyperactivity, hitting behavior, drooling. the mother described him as a very busy child and she could not "trust him out of my (sight) for a second". He rhcild was not potty trained, would chew on sticks and dirt, and had trouble with expressive language.   Follow up on 07/28/04: "Following the reported immunizations with Engerix B, the pt experienced acute sinusitis, sulfa allergy, pharyngitis, viral syndrome, upper respiratory infections, bronchitis, chronic respiratory congestion, chronic adenotonsillitis, and chronic secretory otitis media, and underwent tonsillectomy, adenoidecomy, and bilateral typanostomy/pressure equilization tube placement. Tubes were replaced in April 1999. Original date of insertion not available in medical records received to date. These were not reported as adverse events due to vaccine administration, but were found during the course of review of the pt's medical records. Therefore, they are not listed as adverse events. The most recent information, received on 07/15/04, did not provide the outcome of the alleged event. This report of mercury poisoning is considered to be medically serious by manufacturer (OMIC)." Records form a behavioral program consultant reveealed that during a periodic evaluation 29SEP2002. tje [at was age 6 years, 4 months. he had been receiving in home discrete trial therapy since MAY1998. As of 29 SEPTEMBER 2001, he received in home therapy for an average of 11.5 hours per week and attended a school for developmentally delayed or dyslexic children for an average of 30 hours per week. On 29SEP2001, he could sing children's songs, and was able to draw at or above grade level. He was able to identify 50 sight words. his writing was neat and legible.   Follow up on 08/06/04 states: "The most recent information, received on 08/02/04, did not provide the outcome of the alleged event. This report of mercury poisoning is considered to be medically serious by manufacturer (OMIC).