Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: Blood test, Fatigue, Headache, Illness, Muscle fatigue
Clinical narrative: Muscle twitching/ major muscles started shaking; Slept for 3 days and describes feeling very very sick; muscular issues and neurological issues; muscles are extremely fatigued; rests they cramp up a bit; muscle in her body was in severe pain; vomiting/headache; vomiting/headache; she is so exhausted; This spontaneous case was reported by a patient and describes the occurrence of MUSCLE TWITCHING (Muscle twitching/ major muscles started shaking), ILLNESS (Slept for 3 days and describes feeling very very sick), NERVOUS SYSTEM DISORDER (muscular issues and neurological issues), MUSCLE FATIGUE (muscles are extremely fatigued) and MUSCLE SPASMS (rests they cramp up a bit) in a 62-year-old female patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 03-Dec-2024 at 3:00 PM, the patient received dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (unknown route) 1 dosage form. On 03-Dec-2024, the patient experienced MUSCLE TWITCHING (Muscle twitching/ major muscles started shaking), ILLNESS (Slept for 3 days and describes feeling very very sick), NERVOUS SYSTEM DISORDER (muscular issues and neurological issues), MUSCLE FATIGUE (muscles are extremely fatigued), MUSCLE SPASMS (rests they cramp up a bit), MYALGIA (muscle in her body was in severe pain), HEADACHE (vomiting/headache), VOMITING (vomiting/headache) and FATIGUE (she is so exhausted). At the time of the report, MUSCLE TWITCHING (Muscle twitching/ major muscles started shaking), ILLNESS (Slept for 3 days and describes feeling very very sick), NERVOUS SYSTEM DISORDER (muscular issues and neurological issues), MUSCLE FATIGUE (muscles are extremely fatigued), MUSCLE SPASMS (rests they cramp up a bit), MYALGIA (muscle in her body was in severe pain) and FATIGUE (she is so exhausted) had not resolved and HEADACHE (vomiting/headache) and VOMITING (vomiting/headache) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 09-Dec-2024, Blood test: inconclusive..         No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. Patient recently (last week) received Spikevax and states that at that time within 3 hours all her major muscles started shaking. No pain, just twitching. Within 9 hours every major muscle in her body was in severe pain. Also reported vomiting/headache and she then seemed to get a little better. She slept for 3 days and describes feeling very sick. Then, at around day 3 (post vaccination), she was still having muscular issues and neurological issues where if she walks up a flight of stairs she felt as if she ran 10 miles and when that happens, she vomits because she was so exhausted from walking up the stairs. Also reported her muscles shaking. She stated that she received her vaccine on 03Dec (Tues) at 3:00 PM and by 6:30 PM she was experiencing these effects. She said she had video of her muscle's movements and twitching. She contacted her physician at that time (unclear what the advice was given at the time). She stated that her muscles were shaking and twitching upon rest. She stated that at the time of reporting (the muscles) were not at rest, if she walks up the stairs the muscles were extremely fatigued, and when she rests, they cramp up a bit. She stated the symptoms were actually worse. No treatment information was provided.   This case was linked to US-MODERNATX, INC.-MOD-2024-779140 (E2B Linked Report).; Sender's Comments:  US-MODERNATX, INC.-MOD-2024-779140:Reporter's sister