Age: 39.0
Sex: F
Vaccine: COVID19
Symptoms: Thyroid stimulating immunoglobulin, Thyroiditis
Clinical narrative: Painless thyroiditis; palpitations; anxiety; This literature-non-study case was reported in a literature article and describes the occurrence of THYROIDITIS (Painless thyroiditis) in a 39-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.       Concurrent medical conditions included Hashimoto's disease (Patient with history of Hashimoto's disease for 13 years, euthyroid on levothyroxine.). Concomitant products included LEVOTHYROXINE for Hashimoto's disease.   On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced THYROIDITIS (Painless thyroiditis) (seriousness criterion medically significant), PALPITATIONS (palpitations) and ANXIETY (anxiety). At the time of the report, THYROIDITIS (Painless thyroiditis), PALPITATIONS (palpitations) and ANXIETY (anxiety) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Anti-thyroid antibody: normal (normal) Normal and 107 ng/dl 107 ng/dL. On an unknown date, Blood thyroid stimulating hormone (0.45-4.5): low (Low) 0.02 lIU/mL and low (Low) 0.01 lIU/mL after 1 week. On an unknown date, Free thyroxine index (0.7-1.8): 2.95 ng/dl (High) 2.95 ng/dL and 2.10 ng/dl (High) 2.10 ng/dL after 1 week. On an unknown date, Thyroid stimulating immunoglobulin: less than 1.0 less than 1.0.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered THYROIDITIS (Painless thyroiditis), PALPITATIONS (palpitations) and ANXIETY (anxiety) to be possibly related.    Concomitant product use was not provided by the reporter.   Treatment information was not provided.  The patient was asked to hold her levothyroxine and repeat labs 1 week later again. Radioactive iodine uptake 2 weeks after stopping thyroid hormone showed near absent uptake of 0.22%  This is a literature-non-study case concerning a 39-year-old female patient with history of Hashimoto´s disease for 13 years, euthyroid on levothyroxine, who experienced the serious  unexpected event Thyroiditis. The events occurred approximately 10 days after  the second  dose of mRNA-1273 Moderna vaccine, on an unknown date.  The medical history of Hashimoto´s disease remains a confounder. The benefit-risk relationship of mRNA-1273 Moderna vaccine is not affected by this report.   This case was linked to MOD-2021-372516 (Patient Link).; Sender's Comments: This is a literature-non-study case concerning a 39-year-old female patient with history of Hashimoto´s disease for 13 years, euthyroid on levothyroxine, who experienced the serious  unexpected event Thyroiditis. The events occurred approximately 10 days after  the second  dose of mRNA-1273 Moderna vaccine, on an unknown date.  The medical history of Hashimoto´s disease remains a confounder. The benefit-risk relationship of mRNA-1273 Moderna vaccine is not affected by this report.