Age: 62.0
Sex: M
Vaccine: RAB
Symptoms: Blood pressure increased, Dry mouth, Loss of personal independence in daily activities, Paraesthesia, Paraesthesia oral
Clinical narrative: dry mouth; tingling in tongue; difficulty using and completing tasks on the computer; tingling in arms; spiked blood pressure; Initial information regarding an unsolicited valid non-serious case was received from physician and consumer/non-health care professional via Agency (Reference number- 00878146) and transmitted to Sanofi on 30-Nov-2021.  This case involves a 62-year-old male patient who experienced spiked blood pressure (blood pressure increased), dry mouth, tingling in tongue (paraesthesia oral), difficulty using and completing tasks on the computer (loss of personal independence in daily activities) and tingling in arms (paraesthesia) while receiving vaccine RABIES (HDC) VACCINE [IMOVAX RABIES].  Relevant medical history included nipped by a stray cat. The bite did not leave a mark and did not break the skin.   The patient's past medical treatment(s), vaccination(s) concomitant medication and family history were not provided.   On 19-Nov-2021, the patient received first 1ml dose of suspect RABIES (HDC) VACCINE (lot: T1F912M and expiry date: 25-Nov-2022) via intramuscular route in the left deltoid for post exposure immunization.  Patient did not experience any reaction.   On 22-Nov-2021 he also received second 1ml dose of the same vaccine with an unknown batch number and expiry date via intramuscular route in the right deltoid for post exposure immunization.  On 22-Nov-2021 the patient developed a non-serious spiked blood pressure (blood pressure increased) 3 days following the administration of first dose and same day following the administration of second dose of the RABIES (HDC) VACCINE.  On 26-Nov-2021 he also received third 1ml dose of the same vaccine with an unknown batch number and expiry date via intramuscular route in the left deltoid for post exposure immunization.  The patient reported that there was no incident at first.  On 26-Nov-2021 the patient developed a non-serious dry mouth, tingling in tongue (paraesthesia oral), difficulty using and completing tasks on the computer (loss of personal independence in daily activities) and tingling in arms (paraesthesia) seven days following the administration of first dose, four days following the administration of second dose and same day (8-12 hours later) following the administration of third dose of the RABIES (HDC) VACCINE.  It was reported "The patient saw the doctor on day 5 (17NOV2021) after the bite occurred and was given a tetanus shot per protocol. he did not have trouble with prior to the third dose. The patient is due for the next dose on Friday, 03DEC2021. The patient stated that he has not had any fever or lymph nodes issues. Patient is having apprehensive about the entire process. The patient noted apprehension about the next dose and whether his reaction is due to the dose of IMOVAX or whether he is experiencing this from the bite itself".  No relevant laboratory data was provided.  It was not reported if the patient received a corrective treatment for the events.  Patient was recovered from blood pressure increased event on 22-Nov-2021 (after 2 hours) and also recovered from paraesthesia event on an unknown date.  At time of reporting, the outcome was not resolved for the event dry mouth and unknown for rest of the events.