Sex: M
Vaccine: COVID19
Symptoms: Laboratory test, Myasthenia gravis
Clinical narrative: myasthenia gravis; This is a spontaneous report received from a contactable reporter(s) (Nurse) from medical information team, Program ID.  A 33-year-old male patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), in 2022 as dose 3 (booster), single (Lot number: Unknown) for covid-19 immunisation. The patient's relevant medical history included: "Cold" (unspecified if ongoing), notes: Never had anything in his life other than regular cold in cold season; "droopy eyelid" (unspecified if ongoing). Concomitant medication(s) included: MULTIVITAMINS [VITAMINS NOS]. Vaccination history included: Bnt162b2 (Dose 1, Single), for COVID-19 immunization, reaction(s): "Chills"; Bnt162b2 (Dose 2, Single), for COVID-19 immunization, reaction(s): "Chills". The following information was reported: MYASTHENIA GRAVIS (medically significant) with onset Dec2022, outcome "not recovered". The patient underwent the following laboratory tests and procedures: labs for Myasthenia gravis: Unknown results, notes: labs for Myasthenia gravis. It literally just says Myasthenia gravis. It was done a couple days ago. unknown result. Therapeutic measures were not taken as a result of myasthenia gravis.  Clinical Course: Reported as, other medicines men multivitamin has been taking a good 1-2 years off and on. He had his 1st dose; 2nd dose and a booster dose of Pfizer COVID 19 vaccine and is reporting after those he had myasthenia gravis. The reporter also mentioned her husband was healthy with no history of anything. The reporter stated he was completely healthy, never had anything in his life other than regular cold in cold season. Was diagnosed in Dec2022. fluctuates between 185-187 pounds. This is a lifelong thing, he is in the beginning phases, they call it the snowflake disease because it was so different for everyone. He was occular, he has a droopy eyelid and usually within 2-3 years will progress generalized to other muscles. Reporter thinks it was his left eye and started like 5 weeks ago. He got the 1st 2 like a few months after they became available to the general public beyond the front-line workers and he was fine after those, he had the usually expected like chills. The last one he got a few months ago like 3 months ago for the booster. Causality: she hates to say yes because she doesn't want to come off as an antivaxxer. she was Pro vaccination and was vaccinated herself. In this case she does think it is related considering the timeline. Investigation: labs for Myasthenia gravis. It literally just says Myasthenia gravis. It was done a couple days ago. unknown result. No Prior Vaccinations (within 4 weeks). Diagnosed with Myasthenia Gravis Dec2022. No treatment at this time. has an appointment coming up soon.  The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 has been requested and will be submitted if and when received.; Sender's Comments: Based on available information and the temporal association, a possible contributory role of Comirnaty vaccine cannot be excluded for the reported event of " MYASTHENIA GRAVIS ". The impact of this report on the benefit/risk profile of the Pfizer drug is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees, and Investigators, as appropriate.,Linked Report(s) : US-PFIZER INC-202201369624 same patient/drug,different AE/ dose;US-PFIZER INC-202201369613 same patient/drug,different AE/ dose;