Age: 72.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Fall, Grip strength decreased, Hip fracture, Joint range of motion decreased
Clinical narrative: Knee pain; Broken hip; Fall; barely bend elbow; hand to go limp; Couldn't grip things or raise arm high;   This is a solicited report received from contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program. The reporter is the patient. Other Case identifier(s): 21K-163-4159607-00.  A 72 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administration date 25Aug2021 (Batch/Lot number: unknown) at the age of 72 years as dose 1, single for covid-19 immunisation; adalimumab (HUMIRA), subcutaneous (Batch/Lot number: unknown) for rheumatoid arthritis. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: HIP FRACTURE (medically significant) with onset 25Dec2021, outcome "recovering", described as "Broken hip"; FALL (medically significant) with onset 25Dec2021, outcome "recovering", described as "Fall"; JOINT RANGE OF MOTION DECREASED (non-serious) with onset Aug2021, outcome "not recovered", described as "barely bend elbow"; MUSCULOSKELETAL DISORDER (non-serious) with onset Aug2021, outcome "not recovered", described as "hand to go limp"; GRIP STRENGTH DECREASED (non-serious) with onset 2021, outcome "not recovered", described as "Couldn't grip things or raise arm high"; ARTHRALGIA (non-serious), outcome "not recovered", described as "Knee pain". The action taken for adalimumab was unknown. Therapeutic measures were taken as a result of hip fracture.  The reporter considered "broken hip", "fall", "barely bend elbow", "hand to go limp", "couldn't grip things or raise arm high" and "knee pain" related to bnt162b2.  Causality for Humira (ADALIMUMAB): The reporter's causality for the event(s) of broke hip due to fall unknown onset, vaccine caused hand to go limp and can barely bend elbow/couldn't grip things or raise arm high onset in 2021, vaccine caused hand to go limp and can barely bend elbow/couldn't grip things or raise arm high onset in 2021, broke hip due to fall unknown onset and knee pain was not provided. opinion is that there is no reasonable possibility that the events of broke hip due to fall unknown onset, vaccine caused hand to go limp and can barely bend elbow/couldn't grip things or raise arm high onset in 2021, vaccine caused hand to go limp and can barely bend elbow/couldn't grip things or raise arm high onset in 2021, broke hip due to fall unknown onset and knee pain are related to Humira(adalimumab).  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.   Follow-up(21Jan2022):This is a follow-up solicited report from a Non-Interventional Study based on information received by Pfizer, manufacturer control number: 21K-163-4159607-00. A contactable Female patient reported for herself.  Updated Information included: New events (Broken hip, Fall, Couldn't grip things or raise arm high, Knee pain).  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Based on the available information and a possible contributory role of suspect product BNT162B2 to the development of events joint range of motion decreased, musculoskeletal disorder, grip strength decreased, arthralgia cannot be totally excluded and hip fracture, fall assessed as unrelated to suspect product BNT162B2.