Age: 60.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Pain in extremity, Paraesthesia, Vomiting
Clinical narrative: This case was reported by a consumer via call center representative and described the occurrence of influenza like illness in a 60-year-old female patient who received SHINGRIX for prophylaxis. Previously administered products included SHINGRIX with an associated reaction of injection site pain (1st dose received on 18th May 2018, refer case US2018161610). On 20th July 2018, the patient received the 2nd dose of SHINGRIX. On 21st July 2018, 1 days after receiving SHINGRIX, the patient experienced influenza like illness, muscle pain, bone pain, nausea, vomiting, muscle tightness, foot pain, walking difficulty, numbness in leg and tingling of extremity. On an unknown date, the patient experienced sweating. The patient was treated with gabapentin and tramadol. On an unknown date, the outcome of the influenza like illness, muscle pain, bone pain, nausea, vomiting and sweating were recovered/resolved and the outcome of the muscle tightness, foot pain, walking difficulty, numbness in leg and tingling of extremity were not recovered/not resolved. It was unknown if the reporter considered the influenza like illness, muscle pain, bone pain, nausea, vomiting, muscle tightness, foot pain, walking difficulty, numbness in leg, tingling of extremity and sweating to be related to SHINGRIX. Additional details were provided as follows: On 20th July 2018, the patient went for the 2nd dose of SHINGRIX and when she woke up on 21st July 2018, she felt like she was having the flu, she experienced the following symptoms like every muscle hurt, every bone hurt, nausea, vomiting. The only part of her body that did not hurt was her mouth. All of the symptoms subsided except a few. The patient was still having problems at the time of reporting with both legs because her muscles feel tightened, her knee cap, shin bone and ankles hurt as if she was struck with sledgehammer. On 2nd August 2018, the patient made an appointment with the cardiologist. The cardiologist said that the symptoms were due to the SHINGRIX and was sent to neurologist. She saw the neurologist on 23rd August 2018 at 10:30 in the morning, she went all over the symptoms, and the cardiologist said that it had to do with the SHINGRIX shot. On 24th August 2018 she came back to the physician for some testing with metal reflexes in knees etc. She came back on 30th August 2018 and did testing with electricity and needles into the muscles of her leg and she won't get the results until 17th October 2018. The patient also said that she was having pain underneath the feet. She felt like she had huge marbles underneath the feet and it was difficult walking. She tried Gabapentin 300 mg one capsule twice a day. She took it for a few days with no relief. She was still dealing with numbness and tingling in her upper legs and lower legs at the time of reporting. She was prescribed Tramadol 50 mg tablet and her hands, face and hair were sweating profusely an hour and a half later. She also threw up like six times the day she took it. She called the physician and asked to discontinue taking that product. She said that it did take the pain under her feet away but she could not tolerate the side effects. The neurologist called her today on the day of reporting on 5th September 2018. Lab Comments: On August 24th she came back to the physician for some testing with metal reflexes in knees etc. She came back on August 30th and did testing with electricity and needles into the muscles of her leg and she won't get the results until October 17th.