chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Breast pain, Burning sensation, Central nervous system lesion, Chest discomfort, Chest pain
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Demyelination, Dysuria, Functional gastrointestinal disorder, Gait disturbance, Hypoaesthesia
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Immunology test normal, Insomnia, Lumbar puncture normal, Muscular weakness, Musculoskeletal pain
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Myelitis transverse, Nerve injury, Nervousness, Nuclear magnetic resonance imaging brain normal, Nuclear magnetic resonance imaging spinal cord abnormal
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Plasmapheresis, Pruritus, Restless legs syndrome, Sexual dysfunction, Spinal cord injury
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 48.0
Sex: F
Vaccine: FLU3
Symptoms: Swelling, Tenderness, Urinary retention, Walking aid user
Clinical narrative: My symptoms started between 2-3 weeks after I received the FLUZONE shot. It started with an itchy shoulder blade where it felt like a tag from my shirt was picking at it. It was like that for about a week then I scratched it, it would be painful to touch that area and the pain would radiate around to the front in my left breast area. The itching and picking continued until on December 1st, 2011, I woke up with a weak left leg (the two previous weeks my left leg got very restless and jumpy feeling). On December 2nd my left foot was dragging and I went to see my general family doctor. She got me in for MRI same day. On Monday, December 5th, after getting numb from the chest down during the weekend, and receiving call with MRI results that showed demyelination of spine between shoulder blades on my spine (between T3-T4 area), I was scheduled for two more MRIs on December 6th. I continued to get worse, had tight band feeling wrapping around my chest and I could not walk well by myself so after MRIs were done on the 6th I admitted myself to ER. I spent 3 days receiving high doses of steroids while I was there. At the time of release they didn't know what was wrong, spinal tap showed no infections or anything abnormal. They thought possible MS but they didn't know. In mid-December I saw Neurologist and he gave diagnose of Transverse Myelitis. After I got off first round of steroids my spine swelled up again and on December 23rd went to ER again because I couldn't urinate or walk well. Again got started on prednisone for a longer period of time. Urinary and bowel retention was an issue during this time. When 2nd does of prednisone was finished at the end of January in 2012 I was not better and could not walk well without use of cane or having assistance of another person. In February I entered hospital for plasma exchange treatment for 10 days because I was still numb from chest down, could not walk well, and my left arm as well as both legs were very weak (my left side much worse than right side). I can now walk well by myself without using a cane and returned to work on March 1st. I am not numb anymore but the numbness was replaced by severe pain in my back and chest and burning of right leg constantly. I have had two spinal taps, both showing nothing that proves an infection. I have had several autoimmune tests and nothing was positive. All blood tests were negative for infections, and have no abnormal blood counts. MRI for brain lesions negative. Only one MRI showed lesion on spine that caused nerve damage. I still have bladder issues, sexual dysfunction, cannot sleep at night, extreme pain.
Age: 34.0
Sex: F
Vaccine: VARCEL
Symptoms: Full blood count, Injection site erythema, Injection site pain, Myalgia, Pyrexia
Clinical narrative: Pr developed fever, pain at injection site, redness at injection site, and pain of muscles around neck.
Age: 1.25
Sex: M
Vaccine: DTAP, HEPA
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: Area on Lt thigh red & swollen. Sx started around 4 pm - area dime size. Seen by provider - instructed to apply warm compresses q 4-6 hours. IBU q 6-8h prn.
Age: 27.0
Sex: F
Vaccine: TDAP
Symptoms: Arthralgia, Chills, Diarrhoea, Fatigue, Headache
Clinical narrative: Joint pain, chills, swelling, tiredness, vomiting, diarrhea, headache.
Age: 27.0
Sex: F
Vaccine: TDAP
Symptoms: Swelling, Vomiting
Clinical narrative: Joint pain, chills, swelling, tiredness, vomiting, diarrhea, headache.
Age: 63.0
Sex: F
Vaccine: VARZOS
Symptoms: Erythema, Headache, Local swelling, Pruritus, Skin warm
Clinical narrative: Red, hot to touch & pruritis, HA 2" x 4.5" swelling started developing next day (Thursday) (1" x 1"). Tx: Applied cold compresses, triamcinolone cream.
Age: 48.0
Sex: F
Vaccine: HEPA, MNQ
Symptoms: Abdomen scan, Blood test, Chills, Injection site pain, Malaise
Clinical narrative: 8 hours after received vaccines experienced fever, chills & sore (R) arm at injection site. Several hours later after pain (R) upper arm, axilla, (R) lateral chest to groin, nausea & vomiting, sore throat. Went to ER 1500 4/21/12 received IV fluids, MS, PHENERGAN. Blood draw, Abd CT scan. Felt ill thru 4/23/12.
Age: 48.0
Sex: F
Vaccine: HEPA, MNQ
Symptoms: Nausea, Oropharyngeal pain, Pain, Pyrexia, Vomiting
Clinical narrative: 8 hours after received vaccines experienced fever, chills & sore (R) arm at injection site. Several hours later after pain (R) upper arm, axilla, (R) lateral chest to groin, nausea & vomiting, sore throat. Went to ER 1500 4/21/12 received IV fluids, MS, PHENERGAN. Blood draw, Abd CT scan. Felt ill thru 4/23/12.
Age: 10.0
Sex: M
Vaccine: TDAP
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling
Clinical narrative: Redness, swelling, itchiness approx 1 inch below injection site.
Age: 81.0
Sex: F
Vaccine: VARZOS
Symptoms: Dizziness, Headache, Malaise, Nausea
Clinical narrative: Husband called to say pt was feeling dizzy, nauseous, and generally not well. Pt also has a headache. This is the day after she received the vaccine, and she has talked to her doctor about her adverse reaction.
Age: 35.0
Sex: F
Vaccine: PPV
Symptoms: Dizziness, Erythema, Local reaction, Malaise, Pain
Clinical narrative: Approximately 12 hours after shot, lasting about 1 week - large local reaction - red, swollen, spread onto chest wall & breast. Painful to lift arm. All localized. No respiratory, gastrointestinal, cardiovascular symptoms but did feel malaise & lightheaded. No treatment.
Age: 35.0
Sex: F
Vaccine: PPV
Symptoms: Swelling
Clinical narrative: Approximately 12 hours after shot, lasting about 1 week - large local reaction - red, swollen, spread onto chest wall & breast. Painful to lift arm. All localized. No respiratory, gastrointestinal, cardiovascular symptoms but did feel malaise & lightheaded. No treatment.
Age: 65.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Anaphylactic reaction, Dyspnoea, Hypotension
Clinical narrative: Information has been received from a 65 year old female consumer concerning herself with hypertension, arthritis, SULFA allergy and latex allergy who on 20-APR-2012 was vaccinated with a dose of ZOSTAVAX (Merck) (dose, route and lot# not reported) by injection left arm. Concomitant therapy included PREMARIN, WELLBUTRIN and other unspecific prescriptions. On 20-APR-2012, within minutes of leaving the physicians office, the patient became red, had blotches on her hands and arms, she started to itch, her eyes and tongue began to swell up. The patient stated that she was in her car when this was happening so she went to the local emergency room because she thought she was going to die. The patient reported when she got into the ER she lost consciousness. The patient reported she was treated with IV fluids, dexamethasone (manufacturer unknown), EPIPEN, BENADRYL and other medication. Chemistry profile and CBC (complete blood count) were tested and no result was given. The patient stated that she was admitted to a unit and was discharged from the hospital "the next day" (21-APR-2012). The patient reported she had an "anaphylactoid reaction". The patient reported the swelling in her eyes and tongue have gone down but was still present, she had been experiencing shortness of breath and was just not "feeling well." The patient stated that she was following up with her physician next week. At the time of reporting, the patient was recovering from all reported adverse events. All reported adverse events were considered to be disability and life-threatening by the reporter. Additional information has been requested.
Age: 65.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Anaphylactoid reaction, Dyspnoea, Erythema, Eye swelling, Fear of death
Clinical narrative: Information has been received from a 65 year old female consumer concerning herself with hypertension, arthritis, SULFA allergy and latex allergy who on 20-APR-2012 was vaccinated with a dose of ZOSTAVAX (Merck) (dose, route and lot# not reported) by injection left arm. Concomitant therapy included PREMARIN, WELLBUTRIN and other unspecific prescriptions. On 20-APR-2012, within minutes of leaving the physicians office, the patient became red, had blotches on her hands and arms, she started to itch, her eyes and tongue began to swell up. The patient stated that she was in her car when this was happening so she went to the local emergency room because she thought she was going to die. The patient reported when she got into the ER she lost consciousness. The patient reported she was treated with IV fluids, dexamethasone (manufacturer unknown), EPIPEN, BENADRYL and other medication. Chemistry profile and CBC (complete blood count) were tested and no result was given. The patient stated that she was admitted to a unit and was discharged from the hospital "the next day" (21-APR-2012). The patient reported she had an "anaphylactoid reaction". The patient reported the swelling in her eyes and tongue have gone down but was still present, she had been experiencing shortness of breath and was just not "feeling well." The patient stated that she was following up with her physician next week. At the time of reporting, the patient was recovering from all reported adverse events. All reported adverse events were considered to be disability and life-threatening by the reporter. Additional information has been requested.
Age: 65.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Full blood count, Laboratory test, Loss of consciousness, Malaise, Pruritus
Clinical narrative: Information has been received from a 65 year old female consumer concerning herself with hypertension, arthritis, SULFA allergy and latex allergy who on 20-APR-2012 was vaccinated with a dose of ZOSTAVAX (Merck) (dose, route and lot# not reported) by injection left arm. Concomitant therapy included PREMARIN, WELLBUTRIN and other unspecific prescriptions. On 20-APR-2012, within minutes of leaving the physicians office, the patient became red, had blotches on her hands and arms, she started to itch, her eyes and tongue began to swell up. The patient stated that she was in her car when this was happening so she went to the local emergency room because she thought she was going to die. The patient reported when she got into the ER she lost consciousness. The patient reported she was treated with IV fluids, dexamethasone (manufacturer unknown), EPIPEN, BENADRYL and other medication. Chemistry profile and CBC (complete blood count) were tested and no result was given. The patient stated that she was admitted to a unit and was discharged from the hospital "the next day" (21-APR-2012). The patient reported she had an "anaphylactoid reaction". The patient reported the swelling in her eyes and tongue have gone down but was still present, she had been experiencing shortness of breath and was just not "feeling well." The patient stated that she was following up with her physician next week. At the time of reporting, the patient was recovering from all reported adverse events. All reported adverse events were considered to be disability and life-threatening by the reporter. Additional information has been requested.
Age: 65.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Rash macular, Swollen tongue
Clinical narrative: Information has been received from a 65 year old female consumer concerning herself with hypertension, arthritis, SULFA allergy and latex allergy who on 20-APR-2012 was vaccinated with a dose of ZOSTAVAX (Merck) (dose, route and lot# not reported) by injection left arm. Concomitant therapy included PREMARIN, WELLBUTRIN and other unspecific prescriptions. On 20-APR-2012, within minutes of leaving the physicians office, the patient became red, had blotches on her hands and arms, she started to itch, her eyes and tongue began to swell up. The patient stated that she was in her car when this was happening so she went to the local emergency room because she thought she was going to die. The patient reported when she got into the ER she lost consciousness. The patient reported she was treated with IV fluids, dexamethasone (manufacturer unknown), EPIPEN, BENADRYL and other medication. Chemistry profile and CBC (complete blood count) were tested and no result was given. The patient stated that she was admitted to a unit and was discharged from the hospital "the next day" (21-APR-2012). The patient reported she had an "anaphylactoid reaction". The patient reported the swelling in her eyes and tongue have gone down but was still present, she had been experiencing shortness of breath and was just not "feeling well." The patient stated that she was following up with her physician next week. At the time of reporting, the patient was recovering from all reported adverse events. All reported adverse events were considered to be disability and life-threatening by the reporter. Additional information has been requested.
Age: 1.01
Sex: F
Vaccine: MMR, MNQ, VARCEL
Symptoms: Dyskinesia, Febrile convulsion, Gaze palsy, Listless, Pyrexia
Clinical narrative: Patient was preparing for her last feeding of the evening, latched on to nurse and sucked for about a minute.  She then "jerked" three times, detached herself from my breast and was completely listless.  She would not respond to her name, to patting her cheeks or even the cold air.  Her fists were held very tight but her eyes were rolled to the side and the rest of her body was limp like a rag doll.  She then began to seize, jerking for at least three minutes.  We called 911 at the onset of the incident.  She was transported to the ER and upon admission to the hospital she had a fever of 102.4. She did not have any fever prior to the incident.  She was checked out and it was found that her nose, ears and throat were all clear and no sign of any infections was present.  The diagnosed this as a febrile seizure resulting from a sudden spike in temperature.  I let the Doctor know that patient had her MMR vaccine exactly one week prior to the incident.  While the Doctor would not say that the vaccine caused the seizure, they did say that it could have caused the fever spike that led to the seizure.
Age: 1.01
Sex: F
Vaccine: MMR, MNQ, VARCEL
Symptoms: Unresponsive to stimuli
Clinical narrative: Patient was preparing for her last feeding of the evening, latched on to nurse and sucked for about a minute.  She then "jerked" three times, detached herself from my breast and was completely listless.  She would not respond to her name, to patting her cheeks or even the cold air.  Her fists were held very tight but her eyes were rolled to the side and the rest of her body was limp like a rag doll.  She then began to seize, jerking for at least three minutes.  We called 911 at the onset of the incident.  She was transported to the ER and upon admission to the hospital she had a fever of 102.4. She did not have any fever prior to the incident.  She was checked out and it was found that her nose, ears and throat were all clear and no sign of any infections was present.  The diagnosed this as a febrile seizure resulting from a sudden spike in temperature.  I let the Doctor know that patient had her MMR vaccine exactly one week prior to the incident.  While the Doctor would not say that the vaccine caused the seizure, they did say that it could have caused the fever spike that led to the seizure.
Age: 0.15
Sex: M
Vaccine: DTPHEP, IPV, PPV, RVX
Symptoms: Oedema peripheral, Pain, Pyrexia, Screaming
Clinical narrative: Leg severely swollen, screaming in pain, fever of 101.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: Biopsy bone marrow normal, Biopsy muscle abnormal, Blood lactate dehydrogenase normal, Computerised tomogram abdomen normal, Computerised tomogram normal
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: Computerised tomogram thorax normal, Extranodal marginal zone B-cell lymphoma (MALT type), Immunohistochemistry, Injection site mass, Nuclear magnetic resonance imaging abnormal
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: Radiotherapy, Vaccination site pain
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: BCL-2 gene status assay, Biopsy bone marrow normal, Biopsy muscle abnormal, Blood lactate dehydrogenase normal, Computerised tomogram abdomen normal
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: Computerised tomogram normal, Computerised tomogram thorax normal, Extranodal marginal zone B-cell lymphoma (MALT type) stage I, Immunohistochemistry, Injection site mass
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.
Age: 67.0
Sex: F
Vaccine: FLUX, FLUX, FLUX
Symptoms: Injection site pain, Injection site reaction, Laboratory test abnormal, Muscle mass, Nuclear magnetic resonance imaging abnormal
Clinical narrative: This literature report (initial receipt: 24-Apr-2012) concerns a 67-year-old female patient. In summer 2009, the patient received INFLUENZA vaccination (manufacturer unknown). One month later the patient developed pain and lump in the right arm reportedly in the same area that was vaccinated. Upon initial presentation her symptoms were presumed to be secondary to a torn triceps muscle. She was thus referred to an orthopedist who recommended imaging workup. Magnetic resonance imaging (MRI) of the right upper arm showed a 4.3 x 1.1 x 7.5 cm enhancing mass in the posterior lateral aspect of the long head of the right triceps muscle. Core biopsy revealed low grade lymphoma of small B-cell type. Additional tissue sampling was recommended for further classification and immunophenotyping. The patient underwent incisional biopsy that demonstrated B-cell-type lymphoma infiltrating the skeletal muscle. Immunohistochemical staining was positive for CD 20, BCL2 and pax-5 and negative for CD3, CD5, CD10, CD 23, BCL 6, and cyclin D1, consistent with marginal zone lymphoma. Bone marrow biopsy was negative. Lactate dehydrogenase was within normal limits. She was therefore staged I E with International Prognostic Index score of 1 by virtue of her age. After multidisciplinary consultations, a course of definitive radiation therapy was recommended. The patient underwent CT (computed tomography) simulation in the supine position with alpha-cradle for immobilization. The target lesion was contoured as the gross tumor volume (GTV). The GTV was expanded by 2 cm to create the planned treatment volume. She received 40Gy in 20 fractions with 6MV photons utilizing 3D conformal radiation therapy. She tolerated the treatment well without any unexpected side effects. Physical examination at 1 and 6 months and 1 year after treatment revealed no palpable residual mass, swelling or skin erythema, or range of motion deficits. 6-month post treatment MRI of the right upper arm demonstrated excellent response with no evidence of residual disease. Computerized tomography of the chest, abdomen and pelvis (CT CAP) at 1 year showed no evidence of disease. Reporters comment: The relationship between influenza vaccine injection and the development of MALT lymphoma in this patient is speculative but is, undeniably, an interesting confluence of events. Although the available literature suggests that primary skeletal muscle non-Hodgkin lymphoma is associated with poor prognosis, the case presented here suggests that involved field radiation therapy alone can be an effective treatment for early stage primary skeletal marginal zone lymphoma.