Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Imaging procedure abnormal, Infertility female, Laboratory test abnormal, Migraine, Multiple sclerosis
Clinical narrative: Multiple Sclerosis/cognitive changes, fatigue, blurred vision, Dizziness, dozens of lesions on her brain and spine; neuromyelitis optica spectrum disorder; infertility; emotional lability; migraines; This initial spontaneous report was received from a lawyer and the consumer regarding a case in litigation and refers to an adult female patient of unknown age. The patient's medical history, concurrent conditions and concomitant medications were not reported.   On 02-NOV-2018, when the patient was 24 years old, the patient was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). On 25-JAN-2019, the patient was vaccinated with the second dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) and on 12-FEB-2020, she received the third dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) (strength, dose, lot #, expiry date, anatomical location and route of administration of all doses were not provided) administered for for preventing cervical cancer.  It was confirmed that a physician recommended that patient receive the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccine, which was touted as a safe and effective vaccine.  On an unknown date, following her third dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), the patient  experienced cognitive changes, fatigue, dizziness, and blurred vision (symptoms of Multiple Sclerosis), emotional lability, migraines and neuromyelitis optical spectrum disorder. Her symptoms caused her to go to the emergency room (ER) where she underwent imaging testing which showed dozens of lesions on her brain and spine. After a five-day inpatient hospitalization for multiple tests, the subject was diagnosed with Multiple Sclerosis. Neurologists stated that, unbeknown her, the patient may have had this disease for approximately two years. Additionally, the patient was also told by a reproductive endocrinologist after undergoing multiple tests that, for reasons that could not be explained by the testing, she was infertile.  As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the patient had been unable to engage in activities that a normal young person would enjoy and her ability to function in daily life has been severely affected.  Because of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injuries, she is no longer able to work as a nurse at the hospital where she used to work and cannot go to school for further education as she had planned.  Due to her compromised immunity, she must work remotely and alter her lifestyle around her fragile health.    The patient has suffered and continued to suffer severe and permanent physical injuries, and associated symptomatology and has suffered severe and permanent emotional injuries, including pain and suffering.  Plaintiff also has a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her autoimmune disease and other injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL), therefore the outcome of all the events was considered as not recovered.  The causality between quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) and all the aforementioned events was reported as related and were also considered as disability events.  Upon internal review, multiple sclerosis and neuromyelitis optical spectrum disorder were determined to be medically significant event.