Age: 57.0
Sex: F
Vaccine: COVID19
Symptoms: Lymphoedema
Clinical narrative: auto immune deficiency; lymph edema with puffy legs, thighs, knees; rash on my back that was identified as a shingles; This is a spontaneous report received from a Consumer or other non HCP.  A 58-year-old female patient received BNT162b2 omi xbb.1.5 (COMIRNATY (2023-2024 FORMULA)), on 05Oct2023 as dose 1 (toppac), single (Lot number: HG4677) at the age of 57 years for covid-19 immunisation. The patient's relevant medical history included: "Hypertension" (unspecified if ongoing); "hypokalaemia" (unspecified if ongoing), notes: has been less diuretic and anti-histamine.; "anti-histamine" (unspecified if ongoing); "chickenpox" (unspecified if ongoing), notes: In childhood; "shingles" (unspecified if ongoing), notes: Only on one spot in the neck a couple of times; "Herpes 2 (STD)" (unspecified if ongoing); "COVID-19", start date: Aug2022, stop date: Aug2022. Concomitant medication(s) included: PROPRANOLOL taken for hypertension; HYDROCHLOROTHIAZIDE taken for hypertension. Vaccination history included: johnson & johnson (DOSE 1; Lot number 1821281), administration date: 25Jun2021, when the patient was 55-year-old, for COVID-19 immunization, reaction(s): "lot of pain in her arm and could not lift arm", "lot of pain in her arm and could not lift arm"; johnson & johnson (DOSE 2; Lot number 213D21A), administration date: 07Dec2021, when the patient was 56-year-old, for COVID-19 immunization; BNT162b2 (DOSE 3 (BOOSTER); Lot number: FP7137), administration date: 14Aug2022, when the patient was 56-year-old, for COVID-19 immunization; Bnt162b2 (DOSE 4 (BOOSTER)), administration date: Nov2022, when the patient was 57 years old, for COVID-19 immunization. The following information was reported: HERPES ZOSTER (non-serious) with onset Jan2024, outcome "recovering", described as "rash on my back that was identified as a shingles"; AUTOIMMUNE DISORDER (medically significant), outcome "unknown", described as "auto immune deficiency"; LYMPHOEDEMA (non-serious), outcome "recovered", described as "lymph edema with puffy legs, thighs, knees". The clinical course was reported as follows: The patient received the first Pfizer shot in August2022 as she came down with COVID-19 in Aug2022 (she took 5 days of nirmatrelvir, ritonavir (PAXLOVID) and took 2 weeks of it, it got her better and its always been negative since then). At that time, the latest Pfizer vaccine was not out yet. Originally, the patient got 2 Johnson & Johnson shots, and with the first one she experienced a lot of pain in her arm and could not lift my arm. Then she got the 2 Pfizer shot over the past 2 years. The patient reported she has Herpes 1 which is zoster and Herpes 2 which is a Sexually transmitted disease (STD). She got the result and the levels just had always been 8, a normal level is .08 so this has always been high. The patient indicated that now she got a rash on her back that was identified as a shingles, and it's been 18 months almost that she had swelling, they told her she had lymph edema with puffy legs, thighs, knees almost if she was going to have congestive heart failure, it was all over her body and the legs were like elephantiasis, the ankles were like that of an elephant. Her dietist told her if she kept walking on the feet and get swollen, she was going to break her bones in the feet, that is how bad it was. The patient has been taking antibiotics in the past 18 months and furosemide potassium chloride (LASIX) as treatment for water retention. She went to emergency room 78 times through vascular doctors with okay sound, with no blockage and she refused to go overnight. The patient's cholesterol is over 163 and she is now a vegetarian. The patient got rash on her back last week; therefore, she went to her regular practitioner and told him it was looking like shingles, it was red and warm, so he prescribed her valacyclovir hydrochloride (VALTREX) and the back has started healing and then all of the sudden the legs were getting skinny, and all the water is coming out of her. In the beginning she would not get the COVID shot because according to her, it's said if you had Herpes type 1 but also 2 (because she had these), it would not identify these diseases, so she spent one year without them and she did not want to look down, since she had COVID her zoster level it used to be its 48 almost 49. The patient also reported, they did not want her leg like to be a thousand pounds and she couldn't lift them and now everything has gone away. People thought she was dying, she had no bed to sleep inside for 18 months, and she have been in hotel, a lot of money has been put in also to elevate her leg. Now she is sitting up and her legs are still not swollen even though she is not elevating, usually as soon as she would walk it would grow up. The patient reported she also has another condition called hypokalaemia which is low potassium has been less diuretic and antihistamine, she has to watch neuroleptic. She was recently in the hospital and they gave her neuroleptic and her heart rate went down to 38. The patient underwent the laboratory tests and procedures as aforementioned. Therapeutic measures were taken as a result of herpes zoster, lymphoedema.