Sex: F
Vaccine: COVID19, COVID19, COVID19
Symptoms: Gene mutation, Investigation, Lip pain, Neuropathy peripheral, Skin exfoliation
Clinical narrative: neuropathy in both her feet; She said it started out with her left middle finger going numb on one side. electrical jolts a week later /both her feet are numb and vibrating/her nose started going numb; it feels like electrical jolts/ also had electrical jolts a week later; her nose and the roof of her mouth and tongue started going numb; She said she had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A; She had sores in her mouth and lips ever since receiving both doses of the vaccine.; She had sores in her mouth and lips ever since receiving both doses of the vaccine.; her nails were peeling at one point which has never happened before but has since stopped.; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 60 year-old female patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) as dose 1, single for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: NEUROPATHY PERIPHERAL (medically significant), outcome "unknown", described as "neuropathy in both her feet"; HYPOAESTHESIA (non-serious), outcome "unknown", described as "She said it started out with her left middle finger going numb on one side. electrical jolts a week later /both her feet are numb and vibrating/her nose started going numb"; ELECTRIC SHOCK SENSATION (non-serious), outcome "unknown", described as "it feels like electrical jolts/ also had electrical jolts a week later"; HYPOAESTHESIA ORAL (non-serious), outcome "unknown", described as "her nose and the roof of her mouth and tongue started going numb"; GENE MUTATION (non-serious), outcome "unknown", described as "She said she had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A"; STOMATITIS (non-serious), LIP PAIN (non-serious), outcome "unknown" and all described as "She had sores in her mouth and lips ever since receiving both doses of the vaccine."; SKIN EXFOLIATION (non-serious), outcome "recovered", described as "her nails were peeling at one point which has never happened before but has since stopped.". The patient underwent the following laboratory tests and procedures: investigation: scn11a, notes: positive for a gene mutation called SCN11A; neuropathy, notes: in both her feet. Clinical course: Patient has already received both doses of the Pfizer-BioNTech Covid-19 Vaccine. Patient said that a couple of days after her 1st dose, Patient had some reactions. Patient also said that the rest of the reactions started a month after her 1st dose. Patient said both her feet are numb and vibrating, and it feels like electrical jolts. Patient said it started out with her left middle finger going numb on one side. It also had electrical jolts a week later. Patient said her right fingertips were going numb as well. Patient got tested and was told she has neuropathy in both her feet. And while waiting for the nerve conduction test, her nose and the roof of her mouth and tongue started going numb. Patient had sores in her mouth and lips ever since receiving both doses of the vaccine. Patient said she had a DNA test done for neuropathy which came back positive for a gene mutation called SCN11A. She also mentioned that her nails were peeling at one point which has never happened before but has since stopped. With that, consumer wants to know if it is still safe for her to get the booster dose. She wants to know if this is the maximum amount of neuropathy she'll get from the vaccine or if the booster dose would exacerbate her neuropathy and make it worse. Patient said she is not the only person who is going through the same reaction. Patient wants to know why this is happening, why Pfizer isn't speaking about it publicly, and if it will be a long term side effect or if it will go away. Patient said CDC called her to confirm that these reactions are from the vaccine. DSU: E-transmitting; Possible AE duplicate. Consumer said she was 60 years old when the side effects happened, but she is 61 years old right now.   The lot number for bnt162b2 was not provided and will be requested during follow up.