Age: 79.0
Sex: F
Vaccine: COVID19, UNK
Symptoms: Blood pressure measurement, Cataract, Computerised tomogram abdomen, Constipation, Depression
Clinical narrative: very bad constipation/ severe constipation; panic attacks; affected my heart and blood pressure and digestive system / very high blood pressure; affected my heart and blood pressure and digestive system / very bad constipation/ severe constipation; affected my heart and blood pressure and digestive system/ heart pounding/ heart racing; losing speech; thin of thought; depression was so bad; heavy sweats; dizziness; cataract done; The initial case was missing the following minimum criteria: suspect product. Upon receipt of follow up information on 28Sep2023, this case now contains all required information to be considered valid.   This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP), Program ID:.  An 80-year-old female patient (unknown if pregnant) received bnt162b2 (BNT162B2), on 02Apr2021 as dose 2, single (Lot number: ER8727, Expiration Date: 31Jul2021) and on 08Nov2021 as dose 3, single (Lot number: EW0168, Expiration Date: 30Nov2021) at the age of 79 years for covid-19 immunisation; macrogol 400, propylene glycol (SYSTANE), since Aug2023 (ongoing) (Lot number: Eo/5202H13111) at unk(1 drop per eye). The patient's relevant medical history included: "H. pylori", start date: 1993 (unspecified if ongoing), notes: Onset Date: 30 years ago; "Ulcers", start date: 1993 (unspecified if ongoing); "Lyme", start date: 1993 (unspecified if ongoing), notes: discontinued on visited to doctor, took treatment. Concomitant medication(s) included: PANTOPRAZOLE SODIUM [PANTOPRAZOLE SODIUM SESQUIHYDRATE] taken for immunisation (ongoing); SYNTHROID, start date: 1993 (ongoing); ACIDOPHILUS PROBIOTIC taken for helicobacter infection (ongoing). Past drug history included: Sulfonamides for allergies. The following information was reported: PALPITATIONS (hospitalization) with onset 30Jan2023, outcome "not recovered", described as "affected my heart and blood pressure and digestive system/ heart pounding/ heart racing"; CATARACT (medically significant) with onset 30Jan2023, outcome "recovered", described as "cataract done"; GASTROINTESTINAL DISORDER (hospitalization) with onset 31Jan2023, outcome "not recovered", described as "affected my heart and blood pressure and digestive system / very bad constipation/ severe constipation"; HYPERTENSION (hospitalization) with onset 31Jan2023, outcome "not recovered", described as "affected my heart and blood pressure and digestive system / very high blood pressure"; DEPRESSION (non-serious) with onset 11Jul2023, outcome "unknown", described as "depression was so bad"; DIZZINESS (non-serious) with onset 11Jul2023, outcome "unknown"; HYPERHIDROSIS (non-serious) with onset 11Jul2023, outcome "unknown", described as "heavy sweats"; SPEECH DISORDER (non-serious) with onset 11Jul2023, outcome "recovered", described as "losing speech"; PANIC ATTACK (hospitalization) with onset 11Jul2023, outcome "unknown", described as "panic attacks"; THINKING ABNORMAL (non-serious) with onset 11Jul2023, outcome "recovered", described as "thin of thought"; CONSTIPATION (hospitalization) with onset 11Jul2023, outcome "not recovered", described as "very bad constipation/ severe constipation". The events "affected my heart and blood pressure and digestive system / very bad constipation/ severe constipation", "panic attacks", "losing speech", "thin of thought" and "depression was so bad" required emergency room visit. The events "very bad constipation/ severe constipation", "affected my heart and blood pressure and digestive system/ heart pounding/ heart racing" and "affected my heart and blood pressure and digestive system / very high blood pressure" required physician office visit and emergency room visit. Therapeutic measures were taken as a result of constipation, palpitations, hypertension, gastrointestinal disorder, cataract, panic attack. Therapeutic measures were not taken as a result of speech disorder, thinking abnormal, depression, hyperhidrosis, dizziness. Clinical course was as follow: Taking thyroid medicine for 30 years, also probiotic for H. pylori for 15 years. Blind sided for eye drops by her pharmacy for 12 years, seeing heart doctor been treated since 35. Kept under controlled other things such coming up. Hanc H-pylori bacteria related to ulcer, her husband brought book of co.home told of wells, ponds, lakes burning oxen spring e fall disturbing water, he had to water the well tower. So this was exceed the baterix comes from. The patient had a bad reaction to the shot (second or third shot of COVID-19 shot) a week after, which sent her to the ER, it also affected her heart and blood pressure. and digestive system, what was the preservative in it. Also had cataract for left eye done and having problems with drops. C19 vaccine caused heart to race for 3 months. constipation. Blood pressure back to normal. Did see health doctor. Visited the family doctor when she had C19 shot. when she was taking Eyedrops some problems but C19 wore off, using eyedrops everyday made matters worse. The problem with eye drops put her in the ER 11Jul2023 bad constipation. Blood pressure, racing heart. The patient went to emergency room on 11Jul2023 also due to losing speech, and thin of thought also panic attacks thought she was dying depression was so bad. Back in 19Jul2023. High blood pressure 155/65. The doctor's nurse Noticed BP because she was going to the doctor for 20 years. Taking medicine for constipation didn't help but went off of paused eyedrops all problems went away. Using pure juice for constipation. Works great better than other products. Did get Systane Ultra PF. So far no problem. The patient also had Lyme several years ago and treated (someone gave me free chicken eggs having a reaction to). Did see health doctor.Stop taking Eye drops, taking drops 3x a day even went down to 2 some days. The drops caused heart racing, heavy sweats, severe constipation, very high blood pressure, dizziness - all stopped a month, going off paused eyedrops. Heart Racing, could'n breath (had to take Alrgee pill to because throat would and tongue swelled up.) Blood pressure shoot up to 155/90 scared constipation could not have a bowl movement even though she felt she could go. Going of eye drops and pure juice great also bought eye drops without preservatives. The patient underwent CT abdomen and pelvis for diffuse abdominal pain left upper quadrant pain diffuse in ER on 11Jul2023, which showed Sagittal and coronal reconstruction obtained. Automatic exposure control/ Iterative dose reduction technique. Comparison: None. Findings: Heart is normal in size. Lung bases are adequately aerated. No pleural fluid. Liver shows mild hepatic steatosis. There is a small hiatal hernia. The gallbladder is been removed. There is some nodular thickening of the right adrenal gland may be secondary to an adenoma measuring 1.6cm not fully characterized on the current study but appears stable to the prior study from 2021. The spleen is normal in size. Minimal thickening is also noted left adrenal gland could be secondary to a small adenoma or hyperplasia. Pancreas is within normal limits. Kidneys enhance symmetrically. There is no hydronephrosis. There is a complex exophytic 1.4cm left renal cyst for which follow-up non emergent renal ultrasound and or MRI is recommended. Aorta is normal in caliber. No retroperitoneal adenopathy. Colonic diverticulosis is noted. No evidence diverticulitis. The appendix appears normal. Mild fecal retention is seen in the descending colon and ascending colon. Urinary bladder is grossly within normal limits. Study is challenge secondary to beam hardening artifact from hip prostheses on the right side which results in streak artifact. No ascites is seen. Bones: intact. Degenerative changes.  No follow-up attempts are needed. No further information is expected.