Age: 47.0
Sex: F
Vaccine: COVID19
Symptoms: Herpes simplex, Hypoaesthesia, Joint stiffness, Muscle spasms, Muscle twitching
Clinical narrative: numbness and tingling in my face, fingers and toes; numbness and tingling in my face, fingers and toes; neck pain; muscle twitches; leg pain; shaking; muscle spasms; pins/needles in my hands, feet and arms; heart palpitation; joint stiffness; have not received dose 2 due to continuing neurological; episodes of tachycardia; joint pain; cold chills; very ill with diarrhea, vomiting and fever, followed by body wide nerve pain (zaps); body wide nerve pain (zaps); outbreak of HSV/HSV2 breakout; Vomiting; Fever; This spontaneous case was reported by a consumer and describes the occurrence of PRODUCT ADMINISTRATION INTERRUPTED (have not received dose 2 due to continuing neurological), TACHYCARDIA (episodes of tachycardia), DIARRHEA (very ill with diarrhea, vomiting and fever, followed by body wide nerve pain (zaps)), NEURALGIA (body wide nerve pain (zaps)) and HERPES SIMPLEX (outbreak of HSV/HSV2 breakout) in a 47-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 012M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Adrenal insufficiency (Adrenal insufficiency induced by steroids). Concurrent medical conditions included Drug allergy (Morphine Allergy), Autonomic dysfunction and Herpes simplex virus test positive. Concomitant products included HYDROCORTISONE from 15-Jul-2020 to 15-Feb-2021 for Adrenal insufficiency, VALACICLOVIR HYDROCHLORIDE (VALATREX) and NALTREXONE for an unknown indication.    On 02-Feb-2021 at 12:15 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In February 2021, the patient experienced DIARRHEA (very ill with diarrhea, vomiting and fever, followed by body wide nerve pain (zaps)), NEURALGIA (body wide nerve pain (zaps)), HERPES SIMPLEX (outbreak of HSV/HSV2 breakout), VOMITING (Vomiting) and PYREXIA (Fever). On an unknown date, the patient experienced PRODUCT ADMINISTRATION INTERRUPTED (have not received dose 2 due to continuing neurological), TACHYCARDIA (episodes of tachycardia), HYPOAESTHESIA (numbness and tingling in my face, fingers and toes), PARAESTHESIA (numbness and tingling in my face, fingers and toes), NECK PAIN (neck pain), MUSCLE TWITCHING (muscle twitches), PAIN IN EXTREMITY (leg pain), TREMOR (shaking), MUSCLE SPASMS (muscle spasms), PARAESTHESIA (pins/needles in my hands, feet and arms), PALPITATIONS (heart palpitation), JOINT STIFFNESS (joint stiffness), ARTHRALGIA (joint pain) and CHILLS (cold chills). At the time of the report, PRODUCT ADMINISTRATION INTERRUPTED (have not received dose 2 due to continuing neurological) and HERPES SIMPLEX (outbreak of HSV/HSV2 breakout) outcome was unknown, TACHYCARDIA (episodes of tachycardia), DIARRHEA (very ill with diarrhea, vomiting and fever, followed by body wide nerve pain (zaps)), NEURALGIA (body wide nerve pain (zaps)), NECK PAIN (neck pain), MUSCLE TWITCHING (muscle twitches), TREMOR (shaking), MUSCLE SPASMS (muscle spasms), JOINT STIFFNESS (joint stiffness), VOMITING (Vomiting), PYREXIA (Fever) and CHILLS (cold chills) had resolved and HYPOAESTHESIA (numbness and tingling in my face, fingers and toes), PARAESTHESIA (numbness and tingling in my face, fingers and toes), PAIN IN EXTREMITY (leg pain), PARAESTHESIA (pins/needles in my hands, feet and arms), PALPITATIONS (heart palpitation) and ARTHRALGIA (joint pain) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, COVID-19: Negative. On an unknown date, Epstein-Barr virus antibody positive: Positive.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       No treatment medications were reported.   Most recent FOLLOW-UP information incorporated above includes: On 19-Jul-2021: significant follow up: Patient demographic details, Current medical history, Product details, detailed description of the events experienced and concomitant drug details.Exactly one week after receiving her vaccination, she had woke up with fever and started vomiting. She had vomited and had diarrhea throughout the night and next morning. She also had cold chills, shaking, extreme leg pain, muscle spasms and nerve "zaps" throughout her body. She went to an urgent care who tested her for COVID-19 and the test was negative. A week after this incident, She had an HSV2 breakout and started taking Valtrex daily. For the next 90 days, she experienced tachycardia, numbness and pins/needles in my hands, feet and arms, continued nerve zaps and muscle spasms and joint pain. This mostly resolved by early May, three months after receiving the first dose. She did not get her second dose. I also tested positive for reactivated EBV, which is what is probably causing a lot of the vaccine side effects, along with other latent viruses like HSV. Two weeks ago I was tested for spike protein antibodies and my test was negative. Initially four weeks after my first dose my antibodies were in the 5.14 range. My one dose antibodies are no longer there. I'm very hesitant to go through this again. Most symptoms have resolved although I'm still experiencing intermittent joint pain, occasional heart palpitations and numbness/tingling in my arms/face and sometimes lower extremities (especially in the morning).