Age: 63.0
Sex: F
Vaccine: COVID19
Symptoms: Sedation, Thyroid stimulating immunoglobulin, Thyroxine, Tri-iodothyronine
Clinical narrative: October 9th, I stepped backwards and broke my foot and I have never broken a bone before; So, patient asked the doctor to check her TSH, actually in June, her TSH level had fallen, signaling Thyroid difficulty, it was always within the normal range before; Graves' disease; This is a spontaneous report from a contactable consumer (Patient). A 63-year-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, lot number: ER8733), via an unknown route of administration into left arm on 01Apr2021, as dose 2, single (Age at vaccination: 63-year-old) for Covid-19 immunization. Medical history included: High blood pressure and Concomitant medications included: NEBIVOLOL HYDROCHLORIDE (Bystolic), Vitamin D at 1000 IU, and simvastatin. The patient previously received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, lot number: EN6199), via an unknown route of administration into left arm on 10Mar2021 as dose 1, single (Age at vaccination: 62-year-old) for Covid-19 immunization and experienced Eye problems, had a migraine; It was followed by flashing lights in her left eye. She had more eye problems like a stabbing pain in her eye. The patient had an MRI scan (results unspecified), a TSH eye which found to be within normal range. The patient went to the eye doctor, and they put her on a steroid for 2 weeks and then they had her on an antibiotic and patient was still on it. The patient mentioned treatment medications for eyes problem as Neomycin for 3 weeks and switched to Erythromycin eye gel. The patient had no prior vaccinations (within 4 weeks). The patient had test done for Graves disease. This summer, she had a few symptoms, not really many but then, on 09Oct2021, she stepped backwards and broke her foot. The patient stated that she had never broken a bone before. The patient had TSH test done, and her levels were found to have fallen and signaled Thyroid difficulty. TSH decrease on an unspecified date in Jun2021. The patient thyroid value was found to be even lower after she broke her foot. Her antibody test result was 0.38 on 16Mar2021, 4 to 5 days after she got her first COVID shot, and it was 3.72 at the time of reporting. The patient had Grave's disease on an unspecified date in 2021. Laboratory data included: 3T4 and result was 1.20, within the normal range. she had, these all done on 22Oct2021, T33 was 3.86 and it was high. Then, Thyroid simulating Immunoglobulin (TSI), it was 3.72 and the reference range was up to 0.55. And then, she did Sedation, SED rate was 18, it was in the normal range. TSH was suppressed and the T3 was slightly elevated working at earlier point. TSH decrease on an unspecified date in Jun2021. Events (Grave's disease and foot fracture) were assessed as serious (medically significant) and TSH decrease was assessed as non-serious. Outcome of events was unknown.   Follow-up attempts are completed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202101487625 Same patient and drug, different event separated in time