Age: 66.0
Sex: F
Vaccine: COVID19, COVID19
Symptoms: Swelling face, Systemic lupus erythematosus, Urticaria
Clinical narrative: scratching; itching; Her eye and whole face was swollen; Her eye and whole face was swollen; Her top lip was swollen; High number for lupus; Severe chest pain; Hives all over my body/chronic hives; Little ache; Chills; This is a spontaneous report  from a contactable consumer (patient) from a Pfizer sponsored program. A 66-years-old female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Lot Number: EN6208, Expiry Date: Unknown), via an unspecified route of administration, administered in left arm on 29Mar2021 at 11:15 (at the age of 66-years-old) as dose 2, single; and previously received first dose of bnt162b2 (Lot Number: EN6201, Expiry Date: Unknown), via an unspecified route of administration, administered in left arm on 08Mar2021 (at the age of 66-years-old) as dose 1, single; both for COVID-19 immunization. Medical history included ongoing hereditary haemorrhagic telangiectasia (HHT) (It is a blood vessel disorder that caused AVM. She had numerous embolization in her lungs because of AVM in her lungs. She had it for several years. It was hereditary. Her father and daughter also had it), ongoing high cholesterol (She had it for 20 to 25 years), pancreatitis from Jan2013 (She was in the hospital with it), colitis (she had it for might be 5 or 6 years. It was in remission). The patient was diagnosed with allergies, compromised immune status, respiratory illness, genetic/chromosomal abnormalities, endocrine abnormalities (including diabetes) and obesity. Her mother and brother had diabetes, but she did not have. Concomitant medications included Ongoing EZETIMIBE/SIMVASTATIN (Ezetimibe/simvast 10/20) taken 1 a day for 30 years from an unknown date. She reported that she took COVID vaccine for safety. She did not want to get COVID, and she was of age. She did not have other health issues. No prior vaccinations with in 4 weeks. The following day on Tuesday (30Mar2021), she was okay and had a little bit of chills. She went out in the park with couple of friends, she felt chilly and went back home. She had chills and a little ache and attributed it to the cold. She took 2 Tylenol and a nap and woke up absolutely fine. She thought she was just outside too long. On same day, the ache and chills have completely gone away. She went to bed on Tuesday night and Wednesday morning at 02:00 (31Mar2021) that she developed the hives. She wakes up at 02:00 or 03:00 covered, scratching, and itching. Her eye and whole face was swollen that morning. It was reported that day before that it was not so bad, it was doable. Then that morning she couldn't even open her eyes. A day before, it was decent and it was fading, and now it covered her back, legs, face, neck, everything was covered; (CIU which was chronic hives) from head to toe. She took over the counter Claritin and thought it would last a day or 2. 2 weeks later when it was still chronic. She was shrinking. She went to her primary doctor first. She had been to that doctor for hears. They had it on record that she was there in early April. She only had a phone number for her primary physician. She did not visit emergency room. She went to her primary doctor who told her to take Claritin (Lot: OHE2761A, expiration date: 20Apr2022), but it didn't go away. After another 2 weeks or longer she went to a dermatologist. The dermatologist put her on different prescription medicine. She took 2 Claritin a day and 2 Benadryl (Lot: P121261, expiration date: Aug2023; She didn't take it that often) and a different antihistamine before bed and a prescription cream. They did bloodwork and it came back that she had a high number for lupus. They sent her to a rheumatologist who did bloodwork, and it came back negative. These 3 doctors thought it was from the vaccine, but they did not know what's in it. On the rheumatologist's end everything looked fine. She went to him because of the Lupus factor. She went back to the dermatologist 3 more times, and he changed her medications. Now she took Zyrtec (Cetirizine Hydrochloride 24 hour, Lot: 9EE2658B) and Zantac (acid reducer. Lot: ONE2194B, expiration date: Aug2022. The dermatologist just put her on them) in the morning, and at night Hydroxyzine (She took 2 at night, they were 10mg. It was in an amber colored pharmacy bottle) and Singulair 10 mg (NDC, lot, or expiration date available). She did go on Valtrex at one point, but after 2 or 3 doses she woke up and her top lip was swollen. That night she had severe chest pain, she did not know if it was from the medicine or not. She only had it for one night. It was in early May2021. She never had it again. She only took it 3 times. She took 500mg once a day. It was in an amber colored pharmacy bottle. She took Ryvent 3 times a day. It was 6mg. She was very shaky on that and didn't like taking it. She could not find it to give an NDC, lot, or expiration date. The allergist did more blood work, but there no results yet. She went to 4 doctors and was worse now than she was at the beginning. She asked if this had been heard of before. She felt like Pfizer should know about this. She wondered if she was ever going to get better. She went to 4 doctors and was worse. She did not know how many more medicines she could take. It was 01Jul2021, and this morning was one of the worst. She had been to 4 doctors and been on 14 different medications with no results. Nobody knew what it was, and they said that they did not know what it was in the vaccine and it was probably from it. She underwent relevant diagnostic and confirmatory test for events, for example: from blood tests, cerebrospinal fluid culture, pleural fluid culture, urine culture, diagnostic imaging, (e.g., chest X-ray, MRI) and Investigation assessment: Mammogram, PAP smear, bloodwork. She had lab work with the Allergist that was currently pending results. Patient had a visit to physician's office. The outcome of chills and little ache was recovered on 30Mar2021. The outcome of hives was not recovered and reported as worsened while the outcome of other events were unknown.