Age: 53.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Vomiting
Clinical narrative: still feels headache pain currently; Vomiting; Nausea; Low-grade fever; Chills; Body Pain; Loss of Appetite; Migraine; This case was reported by a consumer via call center representative and described the occurrence of migraine in a 53-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included fibromyalgia (fibromyalgia during conversation and unsure if that history made this event worse).   On 30th April 2019, the patient received the 1st dose of Shingrix (intramuscular) .5 ml. In April 2019, less than a day after receiving Shingrix, the patient experienced migraine. On 1st May 2019, the patient experienced vomiting, nausea, fever, chills, general body pain and appetite lost. On an unknown date, the patient experienced headache. The patient was treated with ondansetron (Zofran) and acetylsalicylic acid, caffeine, paracetamol (Pain Reliever (Aspirin + Caffeine + Paracetamol)). On 1st May 2019, the outcome of the vomiting and nausea were recovering/resolving. On 2nd May 2019, the outcome of the fever and chills were recovering/resolving. On 3rd May 2019, the outcome of the general body pain was not recovered/not resolved and the outcome of the appetite lost was recovered/resolved. On an unknown date, the outcome of the migraine and headache were not recovered/not resolved.   It was unknown if the reporter considered the migraine, vomiting, nausea, fever, chills, general body pain, appetite lost and headache to be related to Shingrix.  Additional details were provided as follows: The patient had a history of fibromyalgia during conversation and was unsure if that history made her condition worse. The patient was a veterinarian. On Tuesday morning from the reporting date, the patient received Shingrix and complains of migraine at night on the same day On Wednesday 1st May 2019, 1 days after receiving a dose of Shingrix the patient experieced nausea, vomiting, low-grade fever, chills, body pain, and loss of appetite. The migraine began Tuesday night, and unreported migraine medication used for relief. On an unknown date, less than a week after receiving Shingrix, the patient was still feelling headache pain. The patient reported the vomiting Wednesday at 5 AM in shower relieved by Zofran injection and she has been taking Zofran 8mg by mouth once daily thereafter to suppress vomiting and reports still feeling nauseous. The low grade fever 99.5 to 99.8 Degree F and chills suppressed by unreported pain reliever which was also a fever reducer caller reports.  The patient had excruciating body pains somewhat relieved by unreported pain and fever reducer.  Loss of appetite relieved at the time of reporting due to caller stating she had desire to eat and indeed ate.  The patient mentioned her physician might had called in or would call in adverse event of her behalf.  The caller requests for GlaxoSmithKline to provide a disclaimer to consumers prior to receiving Shingrix vaccine the possibility of severe side effects and how it may impact daily activities.  The patient considering not receiving the 2nd dose. The patient gave consent to contact her physician and provided contact details for the same.