Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: Eosinophil count, Vaccination site pain
Clinical narrative: Injection site was very sore; This is a spontaneous report received from a contactable reporter (Consumer). The reporter is the patient.  A 62-year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 28Jan2021 (Lot number: EL1283) at the age of 62 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Blood pressure issues" (ongoing); "Cholesterol issues" (ongoing); "Islet cell transplant", start date: 2018 (not ongoing); "Diabetes" (ongoing); "Immunocompromised" (ongoing); "Allergies" (ongoing). Concomitant medications included: ZORTRESS taken for immunosuppressant drug therapy (ongoing); JANUVIA [SITAGLIPTIN PHOSPHATE] taken for diabetes mellitus, start date: 2008 (ongoing); LOSARTAN taken for blood pressure measurement (ongoing); ALLERCLEAR taken for hypersensitivity (ongoing); TACROLIMUS taken for immunosuppressant drug therapy (ongoing). Past drug history included: Simvastatin for High cholesterol, reactions: "Calf cramping", "Major fatigue", notes: She had no lot, national drug code (NDC), or expiry for this medication. The following information was reported: VACCINATION SITE PAIN (non-serious) with onset 28Jan2021, outcome "recovered" (31Jan2021), described as "Injection site was very sore". Relevant laboratory tests and procedures are available in the appropriate section.  Additional Information: The patient received COVID vaccine to avoid getting COVID-19. For the first vaccine, her left arm where the injection site was, was very sore for 3 days, and it started the day after getting the vaccine. It only lasted 3 days then it was ok. She was taking vitamins and supplements, things like that. The patient had blood pressure issues which seemed to start after starting the immunosuppressant drugs. She believed that this may be a side effect of the immunosuppressants she was taking. It may had started 6 months to year after starting the drugs. Back then, she had high blood pressure but now it goes up and down, up and down. Even her doctor could not figure it out. The patient was diabetic and immunocompromised. She had a transplant in the past and she was immunosuppressed. Diabetes started before she got vaccine. She had this since she was 13. She had an Islet cell transplant that functionally cured her diabetes, and she was off insulin. This occurred back in around 2008 but she would be on immunosuppressants the rest of her life. She had hyponatremia, which she said was low blood pressure, where she would have to sit down or she would pass out. So now, she had both hypertension and hypotension. In 2017, she had an episode of hypotension with syncope, and broke her tibia and fibula in her right leg after she passed out. She did not have high cholesterol until after her transplant, but she was on simvastatin but had to take herself off that because of the side effects. She had severe calf cramping in the middle of the night and major fatigue, not sure of the dates of the events having calf cramping, but she had them every night when she was taking it. Since going off the medication, the cramping was gone. She still had fatigue sometimes because of the drugs she was on but, the cramping is gone. Fatigue started before getting the COVID vaccine and the calf cramping.  No follow-up attempts are possible. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-2021360020 Same patient and drug but different dose and events