Sex: U
Vaccine: COVID19, VARZOS, VARZOS
Symptoms: Herpes zoster, Ophthalmic herpes zoster, Pain, Paraesthesia, Vaccination failure
Clinical narrative: Got both doses and twice came down with Shingles; shingles might have gone into eyes; Shingles May 7 of this year; Tingling on the top of my head; Like an insect bite that was painful; Got both doses and twice came down with Shingles; Like an insect bite that was painful; Tingling on the top of my head; Shingles May 7 of this year; shingles might have gone into eyes; This case was reported by a consumer and described the occurrence of suspected vaccination failure in a adult patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis and AD26 COV2 S VACCINE (COVID-19 VACCINE JOHNSON & JOHNSON) for prophylaxis.   On an unknown date, the patient received the 2nd dose of Shingrix and the 1st dose of Shingrix. On 11th April 2021, the patient received COVID-19 VACCINE JOHNSON & JOHNSON. On 7th May 2021, more than 2 years after receiving Shingrix and Shingrix, the patient experienced vaccination failure (serious criteria GSK medically significant), ophthalmic herpes zoster (serious criteria GSK medically significant), shingles, tingling and pain. On 6th September 2021, the patient experienced vaccination failure (serious criteria GSK medically significant), ophthalmic herpes zoster (serious criteria GSK medically significant), shingles, tingling and pain. The patient was treated with antivirals nos (Antiviral (Drug Name Unknown)). On an unknown date, the outcome of the vaccination failure, vaccination failure, ophthalmic herpes zoster, shingles, tingling and pain were unknown and the outcome of the ophthalmic herpes zoster, shingles, tingling and pain were recovered/resolved.   It was unknown if the reporter considered the vaccination failure, vaccination failure, ophthalmic herpes zoster, ophthalmic herpes zoster, shingles, shingles, tingling, tingling, pain and pain to be related to Shingrix and Shingrix.  Additional details were provided as follows: The age at vaccination was not reported. The patient received Shingrix and its booster 3 years ago in 2018, just after turning 50 years.  In 2021, the patient received a COVID shot and then twice came down with Shingles on 7th May 2021 and 6th September 2021. On both times, the patient felt tingling on the top of the head and had what was like an insect bite on the back of head that was painful.  It was later diagnosed as shingles. Antivirals improved things and the patient only had pain in one spot at the back of head both times. The physician thought that this was very unusual. The patient thought that the Shingrix prevented him/her from getting a bad case of Shingles, but at the same time, it seems unusual to get Shingles twice after being vaccinated with Shingrix and its booster. The patient was still grateful for the Shingrix vaccine as the patient did not much suffer from a painful Shingles outbreak particularly because it affected the top of head and might have gone into eye. It was unknown if the reporter considered the vaccination failure, vaccination failure, ophthalmic herpes zoster, ophthalmic herpes zoster, shingles, shingles, tingling, tingling, pain and pain to be related to COVID-19 vaccine. This case was considered as suspected vaccination failure since the details regarding laboratory confirmation of shingles were not provided.; Sender's Comments:  US-GLAXOSMITHKLINE-US2021AMR266165:Same reporter.