Sex: F
Vaccine: COVID19
Symptoms: Dyspnoea, Joint stiffness, Rheumatoid arthritis
Clinical narrative: her top 15 knuckles would not move/April and she says she had RA for 6 hours not 10 years.; hands clenched into fists; trouble breathing; This spontaneous case was reported by a consumer and describes the occurrence of RHEUMATOID ARTHRITIS (her top 15 knuckles would not move/April and she says she had RA for 6 hours not 10 years.), JOINT STIFFNESS (hands clenched into fists) and DYSPNOEA (trouble breathing) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 immunisation.     No Medical History information was reported.   On 18-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 19-Apr-2021, the patient experienced JOINT STIFFNESS (hands clenched into fists) (seriousness criterion medically significant). In 2021, the patient experienced DYSPNOEA (trouble breathing) (seriousness criterion medically significant). On an unknown date, the patient experienced RHEUMATOID ARTHRITIS (her top 15 knuckles would not move/April and she says she had RA for 6 hours not 10 years.) (seriousness criterion medically significant). At the time of the report, RHEUMATOID ARTHRITIS (her top 15 knuckles would not move/April and she says she had RA for 6 hours not 10 years.), JOINT STIFFNESS (hands clenched into fists) and DYSPNOEA (trouble breathing) outcome was unknown.            Concomitant product was not provided by the reporter.  Patient received the first Moderna shot and was just fine. Patient received the second shot on 18Apr2021 and on 19Apr2021, she woke up with her hands clenched into fists, top 15 knuckles would not move. Patient went to a walk-in clinic and was told a guinea pig and was given steroids. She only took half and it helped, she wanted to save the rest for later in case this happened again. Patient was told that she have symptoms of Rheumatoid Arthritis (RA) for 10 years. She saw her primary care doctor which referred her to a Rheumatologist. Blood tests done showed that she has the markers for RA for 10 years and is also a carrier for Tuberculosis. Doctors won't give her steroids and want to start on RA medication but patient reported that she did not have RA. This has been going on since April and patient said she had RA for 6 hours and not 10 years. Patient said that every 3 to 10 days she gets it in a different joint, the inner lining of lungs has RA. Patient said she knows this because she had trouble breathing and looked it up and she has RA in her lungs.  Treatment medication included steroids.  Not able to copy Company Comment due to limited characters. Not able to regenerate iNarrative. DJG; Sender's Comments: This spontaneous case concerns a female patient, of unknown age, with no medical history reported, who experienced the unexpected, serious AESI of rheumatoid arthritis and the unexpected, serious events of joint stiffness and dyspnoea. The event joint stiffness occurred 1 day after administration of the second dose of the Moderna mRNA-1273 vaccine. The start dates of the events rheumatoid arthritis and dyspnoea were not provided. The patient woke up with her hands clenched into fists, her knuckles would not move. She sought consult and was given steroids (unspecified). Treatment information for the events rheumatoid arthritis and dyspnoea were not provided. The outcomes of the events were unknown at the time of the report. The rechallenge was not applicable as no additional dosing will be given. The benefit-risk relationship of the Moderna mRNA-1273 vaccine is not affected by this report.