Age: 24.0
Sex: F
Vaccine: VARCEL
Symptoms: Anaemia, Erythema, Pharyngitis
Clinical narrative: Information has been received from a physician, concerning a pregnant 24 year old female patient with no previous pregnancies, and no other concurrent conditions, who on 06Sep2002 was vaccinated with a dose of varicella virus vaccine live (Lot # indicated unknown). It is reported that the patient was vaccinated and she is "now" 6 weeks pregnant. The pt experienced exposure to varicella vaccine live during pregnancy. Follow up information received from a physician through a Merck Pregnancy Registry for varicela virus vaccine live provided information that pt had no local reaction at vaccination site following vaccination with varicella virus vaccine live, an no chicken pox or herpes zoster symptoms post vaccination. She had not been tested for varicella antibodies before vaccination with varicella virus vaccine live. The following tests were performed during the patient's pregnancy: an ultrasound on 08Jan2003 was done to determine "dating" and showed normal results, no abnormalities were detected, a maternal serum alpha fatoprotein was declined, and a glucose test done on 03Mar2003 for screening resulted 118 which was normal. It was reported she had no complications, infections or illnesses during her pregnancy, although she developed anemia during pregnancy, and was treated with ascorbic acid (+) cyanocobalamin (+) ferrous fumarate (CHROMAGEN) 1 daily, which stated on 07Mar2003 (also reported as 08Mar2003) and was continued through to the time of her delivery. It was noted the pt was also started on acetaminophen (+) caffeine (ASPIRIN FREE EXCEDRIN) in November 2003 (dose and indication not reported). It was also noted she had no complications during labor and delivery. On 02Jun2003 at 16:22PM, 39 weeks from her last LMP the patient vaginally delivered a term, live born, 8 pound 9 ounce, 19.5 inch normal female infant. The female infant had an apgar of "9" at one and five minutes. On physical examination the infants pulse rate was 140, respiration rate was 44, and all systems were noted as normal. The infant's palate was intact. She had normal female genitals, patent anus, and her heart was assessed as having a regular rate and rhythm and no murmur. It was reported the infant had no congenital anomalies, complications and other abnormalities. It was noted the female infant did not have any features of congenital varicella zoster syndrome. The physician noted an initial risk assessment for the infant at birth was maternal group B strep and reported, "two doses of antibiotic with delivery". On 04Jun2003 during physical examination it was noted that the infant's pulse rate was 148, respiratory rate 48, and all systems were "normal", and she had developed erythema toxicum on her chest. The infant was discharged at 17:20PM with no problems. The physician reported the infant had no adverse events. Follow up information received on 16Jun2003 which pertained to events that occurred during the patient's pregnancy following the administration of varicella virus vaccine live. This information included the following adverse experience: anemia (onset unknown). Additional follow up was received in infant medical records which pertained to events that occurred to the mother during the pregnancy and the infant following delivery. The information included the following adverse experiences: maternal group B strep (onset unknown) and erythema toxicum (infant; 04Jun2003). Unspecified medical attention was sought. No additional information is expected.