Age: 71.0
Sex: F
Vaccine: COVID19
Symptoms: Pruritus, Respiratory rate
Clinical narrative: body felt hot; itchy all over; swelling of upper airway; prickling/tingling; Redness/erythema; Lost sense of smell and taste; Lost sense of smell and taste; Hives all over her body, 4 inches in size,l,they are jumbo in size/MD advised some of the biggest hives he had ever seen; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of ANOSMIA (Lost sense of smell and taste), AGEUSIA (Lost sense of smell and taste), ANGIOEDEMA (Hives all over her body, 4 inches in size,l,they are jumbo in size/MD advised some of the biggest hives he had ever seen), FEELING HOT (body felt hot) and PRURITUS (itchy all over) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 042B21A and 017C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Drug allergy (allergies to certain medication.).   On 30-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 28-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 02-Jun-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced ANGIOEDEMA (Hives all over her body, 4 inches in size,l,they are jumbo in size/MD advised some of the biggest hives he had ever seen). On 02-Jun-2021 at 7:00 AM, the patient experienced ANOSMIA (Lost sense of smell and taste), AGEUSIA (Lost sense of smell and taste), FEELING HOT (body felt hot), PRURITUS (itchy all over), PHARYNGEAL SWELLING (swelling of upper airway), PARAESTHESIA (prickling/tingling) and ERYTHEMA (Redness/erythema). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) (intravenous) on 05-Jun-2021 at an unspecified dose and frequency and CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) (oral) at a dose of UNK, qd. On 20-Jun-2021 at 7:00 AM, ANOSMIA (Lost sense of smell and taste), AGEUSIA (Lost sense of smell and taste), FEELING HOT (body felt hot), PRURITUS (itchy all over), PHARYNGEAL SWELLING (swelling of upper airway), PARAESTHESIA (prickling/tingling) and ERYTHEMA (Redness/erythema) had resolved and ANGIOEDEMA (Hives all over her body, 4 inches in size,l,they are jumbo in size/MD advised some of the biggest hives he had ever seen) had resolved with sequelae.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 05-Jun-2021, Blood pressure measurement: 159/84 mmHg (High) at 13:00. On 05-Jun-2021, Body temperature: 97.9 f (normal) at 13:00. On 05-Jun-2021, Full blood count: results not provided (Inconclusive) Results available but not provided. On 05-Jun-2021, Respiratory rate: 18 (normal) at 13:00.         No concomitant medications were provided.  The patient endorsed feeling sleepy as a result of treatment with intravenous Benadryl and Zyrtec. She stopped taking the Zyrtec tablets on an unknown date and reported feeling miserable until she eventually recovered. The patient also reported that sunlight on the hives increased itching.   This case was linked to MOD-2021-209719 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 02-Jul-2021: initial additional.