Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Cardiac stress test, Computerised tomogram, Electrocardiogram, Incomplete course of vaccination, Myocardial necrosis marker
Clinical narrative: first dose on 06-Jun-2021 and has not received 2nd/Patient has not received 2nd dose; heart pounding out of chest; she experienced heart racing and throat swelling; she experienced heart racing and throat swelling/22 days after receiving the 1st dose she experienced "heart pounding out of chest"; This spontaneous case was reported by a consumer and describes the occurrence of PHARYNGEAL SWELLING (she experienced heart racing and throat swelling) and PALPITATIONS (she experienced heart racing and throat swelling/22 days after receiving the 1st dose she experienced "heart pounding out of chest") in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 047B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 06-Jun-2021 at 9:50 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 06-Jun-2021, the patient experienced PHARYNGEAL SWELLING (she experienced heart racing and throat swelling) (seriousness criterion medically significant) and PALPITATIONS (she experienced heart racing and throat swelling/22 days after receiving the 1st dose she experienced "heart pounding out of chest") (seriousness criterion medically significant). On 28-Jun-2021, the patient experienced PALPITATIONS (heart pounding out of chest). On an unknown date, the patient experienced INCOMPLETE COURSE OF VACCINATION (first dose on 06-Jun-2021 and has not received 2nd/Patient has not received 2nd dose). The patient was treated with METOPROLOL for Adverse event, at a dose of UNK UNK, bid and DEXAMETHASONE (DECADRON [DEXAMETHASONE]) for Heart racing and Throat swelling, at an unspecified dose and frequency. On 06-Jun-2021, PALPITATIONS (she experienced heart racing and throat swelling/22 days after receiving the 1st dose she experienced "heart pounding out of chest") had resolved. At the time of the report, PHARYNGEAL SWELLING (she experienced heart racing and throat swelling) and INCOMPLETE COURSE OF VACCINATION (first dose on 06-Jun-2021 and has not received 2nd/Patient has not received 2nd dose) had resolved and PALPITATIONS (heart pounding out of chest) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Cardiac stress test: normal (normal) Normal. On an unknown date, Computerised tomogram: normal (normal) Normal. On an unknown date, Electrocardiogram: normal (normal) Normal. On an unknown date, Myocardial necrosis marker: normal (normal) Normal.     mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant medications were not provided.  Patient had not received 2nd dose. Doctor said not to get booster. Patient states 10 to 15 minutes after first dose she experienced heart racing and throat swelling and by 10:05 am a doctor at vaccine site administered Decadron due to heart racing and throat swelling symptoms after receiving the first dose of Moderna vaccine. Patient states 22 days after receiving the 1st dose she experienced heart pounding out of chest and went to emergency room who then referred her to cardiologist. Said no symptoms were ongoing and no cardiac episode had not occurred. Patient wore a monitor for a month. Patient never had cardiac problems prior to receiving first dose.  This case concerns a 59-year-old female patient with no previous relevant medical history, who experienced the serious unexpected events of Palpitations and Pharyngeal swelling and an additional non serious unexpected event of Palpitations after Spikevax (mRNA- 1273 vaccine / Moderna COVID-19 Vaccine). Incomplete course of vaccination was also captured. The first event of Palpitations and Pharyngeal swelling occurred immediately after the first dose of Spikevax. Decadron was administered at the vaccination site with complete resolution. The second event of Palpitations occurred 22 days after vaccination, patient was evaluated by a cardiologist without pathological findings.  The rechallenge was not applicable since the drug was discontinued. The benefit-risk relationship of Spikevax vaccine is not affected by this report.; Sender's Comments: This case concerns a 59-year-old female patient with no previous relevant medical history, who experienced the serious unexpected events of Palpitations and Pharyngeal swelling and an additional non serious unexpected event of Palpitations after Spikevax (mRNA- 1273 vaccine / Moderna COVID-19 Vaccine). Incomplete course of vaccination was also captured. The first event of Palpitations and Pharyngeal swelling occurred immediately after the first dose of Spikevax. Decadron was administered at the vaccination site with complete resolution. The second event of Palpitations occurred 22 days after vaccination, patient was evaluated by a cardiologist without pathological findings.  The rechallenge was not applicable since the drug was discontinued. The benefit-risk relationship of Spikevax vaccine is not affected by this report.