Age: 25.0
Sex: F
Vaccine: COVID19
Symptoms: Liver function test, Liver injury, Nausea, Pyrexia, Vomiting
Clinical narrative: liver damage due to dehydration; nausea; vomiting; dehydrated; could not go to work because of illness; could not eat or drink and hold anything down; feverish; lost lot of hair; This spontaneous case was reported by a patient (subsequently medically confirmed) and describes the occurrence of LIVER INJURY (liver damage due to dehydration), NAUSEA (nausea), VOMITING (vomiting) and DEHYDRATION (dehydrated) in a 25-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 008C21A and 030B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Anxiety. Concomitant products included CLONAZEPAM for Anxiety, AMFETAMINE ASPARTATE, AMFETAMINE SULFATE, DEXAMFETAMINE SACCHARATE, DEXAMFETAMINE SULFATE (ADDERALL) for an unknown indication.   On 07-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 05-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 2 dosage form. On 06-May-2021, the patient experienced NAUSEA (nausea) (seriousness criterion hospitalization), VOMITING (vomiting) (seriousness criterion hospitalization), DEHYDRATION (dehydrated) (seriousness criterion hospitalization), DYSPHAGIA (could not eat or drink and hold anything down) and PYREXIA (feverish). On 07-May-2021, the patient experienced LIVER INJURY (liver damage due to dehydration) (seriousness criteria hospitalization and medically significant). In May 2021, the patient experienced ALOPECIA (lost lot of hair). On an unknown date, the patient experienced IMPAIRED WORK ABILITY (could not go to work because of illness). The patient was hospitalized until 12-May-2021 due to DEHYDRATION, LIVER INJURY, NAUSEA and VOMITING. On 09-May-2021, NAUSEA (nausea), VOMITING (vomiting) and DYSPHAGIA (could not eat or drink and hold anything down) had resolved. On 12-May-2021, DEHYDRATION (dehydrated) had resolved. At the time of the report, LIVER INJURY (liver damage due to dehydration) had resolved and ALOPECIA (lost lot of hair), IMPAIRED WORK ABILITY (could not go to work because of illness) and PYREXIA (feverish) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 06-May-2021, Blood pressure measurement: unknown (Low) blood pressure dropped. On 07-May-2021, Liver function test: unknown (High) Elevated liver enzymes.         Patient was also reported to be taking birth control pills as concomitant medications.  Patient reported that several tests were done in the hospital.  Patient was reported to stay in the ICU on 07-MAY-2021. Patient was treated with iv fluids, iv potassium and anti-nausea medication.  Patient was reported to specifically ask if she can get some refund for the money spent for treatment at the hospital and wanted to talk to somebody from Moderna safety team and was expecting call from safety team to clarify if any refund policy for the injury and answer her questions.  Based on the current available information and temporal association between the use of the product and the start date of the events,   a causal relationship cannot be excluded.   This case was linked to MOD-2021-213275 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events,   a causal relationship cannot be excluded.