Age: 62.0
Sex: F
Vaccine: VARZOS
Symptoms: Anxiety, Arthralgia, Asthenia, Axillary pain, Balance disorder
Clinical narrative: Photosensitivity/ cannot look at screens and the photosensitivity; Burning sensation on top of head; pain in her neck; Lymph node pain with edema; Armpit pain; Lymph node pain with edema; these side effects have affected her life, she cannot do yoga which is her form of keeping healthy; She still takes meclizine for dizziness and balance; Dizziness/ makes her feel dizzy; Body aches; Joint pain; Weakness/fatigue; Chills; fatigue; one night she woke up with extreme pain in head/ slight headache; Anxious feeling in chest; Noise sensitivity/ she developed high sensitivity to noise at any kind of volume; This case was reported by a consumer via call center representative and described the occurrence of chills in a 62-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included breast cancer (had 11 years before reporting) and shingles (was diagnosed previously). Previously administered products included Shingrix with an associated reaction of diarrhoea (received 1st dose on 17th September 2019 and experienced extreme diarrhea for 48 hours after that dose, refer case US2020AMR038353).   On 4th February 2020, the patient received the 2nd dose of Shingrix (intramuscular). On 4th February 2020, less than a day after receiving Shingrix, the patient experienced chills. On 5th February 2020, the patient experienced general body pain, joint pain and weakness. On 6th February 2020, the patient experienced dizziness. In February 2020, the patient experienced hyperacusis, headache, chest anxiety feeling of and fatigue. On an unknown date, the patient experienced photosensitivity, burning sensation, neck pain, lymph node pain, axillary pain, enlargement of lymph nodes, activities of daily living impaired and balance difficulty. The patient was treated with meclozine hydrochloride (Meclizine). On an unknown date, the outcome of the chills, general body pain, joint pain, hyperacusis, photosensitivity, fatigue, burning sensation, neck pain, lymph node pain, axillary pain, enlargement of lymph nodes, activities of daily living impaired and balance difficulty were unknown and the outcome of the dizziness and weakness were not recovered/not resolved and the outcome of the headache and chest anxiety feeling of were recovered/resolved.   It was unknown if the reporter considered the chills, general body pain, joint pain, dizziness, hyperacusis, photosensitivity, headache, chest anxiety feeling of, weakness, fatigue, burning sensation, neck pain, lymph node pain, axillary pain, enlargement of lymph nodes, activities of daily living impaired and balance difficulty to be related to Shingrix.  Additional information was provided as follows: The patient received the second shingrix vaccine in her upper left arm on tuesday. The patient experienced chills on tuesday and wednesday night, she also had body aches which were more enhanced at her joints. On Thursday, she started having dizziness and was still having dizziness. The patient was spiraled after thursday, she developed high sensitivity to noise at any kind of volume, she was almost in tears due to the noise sensitivity and still suffered from it. She also developed photo-sensitivity, her eyes were sensitive to light, she cannot look at screens and the photosensitivity makes her feel dizzy. The patient had a slight headache which was off and on throughout the day, one night she woke up with extreme pain in head from temple to temple, headache subsided in past two days. She reported anxious feeling in her chest for first week after the vaccine. She also reported weakness and fatigue which she still had, weakness started on wednesday after the vaccine. The patient reported a pain in her neck which was similar to pain she had when she was diagnosed with shingles previously, the neck pain was accompanied by a burning sensation at top of head that came and went at random times. less than one month after receiving the shingrix vaccine, her lymph nodes are more sensitive with pain and edema around her lymph nodes, she had lymph node pain in her armpits. These side effects have affected her life, she cannot do yoga which was her form of keeping healthy. The patient was taking meclizine for dizziness and balance. The patient received both vaccines at her doctor's office, she did not feel comfortable providing her doctor's contact information. The reporter did not consent to follow up.