Age: 19.0
Sex: F
Vaccine: DTAP, HEP, HEPA, HPV9, IPV, TYP, DTAP, HEP, HEPA, HPV9, IPV, TYP
Symptoms: Amenorrhoea, Menstruation irregular
Clinical narrative: 8 months after these vaccines, l had one period. Then 15 months later, I had another cycle. 8 months after that, one more cycle. As It stands, I have yet to have a period since her birth!  A delayed period; This report was identified from a line listing obtained on request by the Company from the FDA under the Freedom of Information Act (VAERS # 802418) on 26-SEP-2019 referring to a 19 year old female patient.   The patient was stress at college, over-exercised and with severe calorie restriction (the patient was consuming about 1800 kcal/day but burning about 2700) that she made herself immunocompromised at the time of injection. The patient wasn't allergic to medications, food, or other products. There were no prescriptions, over-the-counter medications, dietary supplement or herbal remedies being taken at the time of vaccination. There was no adverse event following any previous vaccine. The patient wasn't pregnant at the time of vaccination.  On 22-FEB-2008 the patient was vaccinated with hpv rl1 6 11 16 18 31 33 45 52 58 vlp vaccine (yeast)(GARDASIL 9) (first dose, route, lot# and expiration date were not provided). On the same day the patient also received first dose of diphtheria toxoid, pertussis acellular 5-component vaccine, tetanus toxoid(DAPTACEL), hepatitis A virus vaccine inactivated (HAVRIX), hepatitis B virus vaccine rHBsAg (yeast) (ENGERIX-B), poliovirus vaccine inactivated (Vero) (IPOL), typhoid vi polysaccharide vaccine (TYPHIM VI) and other unspecified vaccine for prophylaxis (strength, frequency, lot #, route, expiry date were not reported). On 25-FEB-2008, the patient received a booster of hpv rl1 6 11 16 18 31 33 45 52 58 vlp vaccine (yeast)(GARDASIL 9). On 15-MAR-2008, the patient experienced amenorrhea. Unspecified medical tests were made to discover the cause of amenorrhea. In October 2008 (reported as 8 months after these vaccines), the patient had one period. Then 15 months later, the patient had another cycle. 8 months after that, one more cycle. Then the patient got married and began birth control which brought her monthly cycle back. The patient had originally attributed her amenorrhea to over exercise and school stress but when she stopped taking the pill 4 years later, the patient had one period three months after stopping the pill. The patient was in perfect health otherwise and had no explanation as to why her period ceased when she stopped the pill. It was then that she began to suspect that the vaccines she had just before her symptoms began may have been the culprit. After that one period, she conceived her son. It took 2 years after his birth to have another cycle. After that one period in October 2016, her daughter was conceived. The patient had yet to have a period since her daughter's birth (not recovered). Her breastfeed kids which may account for a delayed period. The patient suspect that because of her stress, over-exercise, and severe calorie restriction that she made herself immunocompromised at the time of injection which caused this amenorrhea. The final causality assessment between amenorrhea and the suspect therapies was unknown.  The result of amenorrhea was disability or permanent damage.  Follow up information has been received via telephone call on 30-OCT-2019.  A phone call was placed to Physician but it was answered by receptionist. The phone call was transferred to Medical Assistant but  was unable to assist and was unable to locate a patient with incomplete identifiers.