Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Restless legs syndrome, Suicidal ideation, Temperature intolerance, Tremor, Urinary incontinence
Clinical narrative: multiple sclerosis (MS)/headaches/vision prob/anxiety/depression/muscle rigidity,weakness/dizziness/numb,tremors/poor balance/vertigo/difficulty walking/restless leg/overactive reflex/fatigue/pain/heat intolerance/pins,neddles/reduced sensation/insom; thoughts of suicide; Information has been received from a lawyer regarding a case in litigation and refers to an adult female patient (pt) (exact age was not provided). The pt's medical history, concurrent conditions and concomitant therapies were not provided. On 04-NOV-2019, at the age of 24 years, the pt was vaccinated with the first dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection, administered for prophylaxis (exact dose, strength, lot #, expiry date, and route of administration were not provided), as recommended by her health care provider. On an unknown dates, the pt received second and third dose of quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). On an unknown date (reported as a month after the third vaccination), the pt woke up feeling exhausted and had bad headaches. Days later, she had severe vision problems including double vision, blurred vision, and issues with her pupils. This was such an impairment she was not able to drive. She then had numb lips which spread to half of her body. On an unknown date, she was admitted into the hospital. The magnetic resonance imaging (MRI's) done showed brain damage. She was experiencing symptoms of multiple sclerosis (MS). This led to anxiety, depression, and thoughts of suicide. As the months progressed, the pt began having muscle weakness, dizziness, the right side of her body going numb, tremors in her upper limbs, muscle rigidity and weakness, poor balance, vertigo, difficulty walking, loss of coordination, muscle spasms, restless legs, difficulty raising her foot, numbness of her face, insomnia, overactive reflexes, chronic fatigue, and headaches. She also experienced widespread pain, heat intolerance, pins and needles in her extremities, reduced sensation of touch, excessive urination, tingling, urine and fecal incontinence, anxiety, mood swings, slurred speech, depression and difficulties with concentration and her memory. As a result of her post-quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, the pt has been unable to engage in activities that a normal young person would enjoy. She was no longer able to drive due to vision problems, needed assistance walking. Her symptoms have hindered her ability to perform in class, and she was now failing. Prior to the quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) vaccines, she had a 3.8-4.0 GPA in college pursuing her dream of becoming a veterinarian. Based upon her chronic and severe post-Gardasil symptoms, the pt has been diagnosed with various medical conditions, including but not limited to, multiple sclerosis (MS). The pt contended that her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological, injuries, including but not limited to MS, as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which were alleged herein and all of which were caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. The pt had suffered and continued to suffer severe and permanent physical injuries, and associated symptomology and had suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the pt had suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of the events was considered not recovered.   The reporter considered all the events to be related to quadrivalent human papillomavirus (types 6,11,16,18) recomb. vaccine (GARDASIL). The reporter considered all events to be disabling.  Upon internal review, the events of MS and thoughts of suicide were determined to be medically significant.