Age: 65.0
Sex: M
Vaccine: COVID19
Symptoms: Carpal tunnel syndrome, Post procedural discomfort, Psoriatic arthropathy, Vaccination site pain
Clinical narrative: PSORIATIC ARTHRITIS THROUGH OUT ALL JOINTS; Carpal tunnel syndrome; NORMAL DISCOMFORT FROM ANY SURGERY; ARM TENDER SORE AT INJECTION SITE SECOND COVID VACCINE; This spontaneous case was reported by a consumer and describes the occurrence of PSORIATIC ARTHROPATHY (PSORIATIC ARTHRITIS THROUGH OUT ALL JOINTS) and CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome) in a 66-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ADALIMUMAB (HUMIRA) solution for injection for Rheumatoid arthritis and Psoriatic arthritis.    Concurrent medical conditions included Psoriatic arthritis and Rheumatoid arthritis.   In March 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. In April 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient started ADALIMUMAB (HUMIRA) (Subcutaneous) 1 dosage form once a week. In April 2021, the patient experienced VACCINATION SITE PAIN (ARM TENDER SORE AT INJECTION SITE SECOND COVID VACCINE). On an unknown date, the patient experienced PSORIATIC ARTHROPATHY (PSORIATIC ARTHRITIS THROUGH OUT ALL JOINTS) (seriousness criterion medically significant), CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome) (seriousness criterion medically significant) and POST PROCEDURAL DISCOMFORT (NORMAL DISCOMFORT FROM ANY SURGERY). At the time of the report, PSORIATIC ARTHROPATHY (PSORIATIC ARTHRITIS THROUGH OUT ALL JOINTS) and CARPAL TUNNEL SYNDROME (Carpal tunnel syndrome) was resolving and POST PROCEDURAL DISCOMFORT (NORMAL DISCOMFORT FROM ANY SURGERY) and VACCINATION SITE PAIN (ARM TENDER SORE AT INJECTION SITE SECOND COVID VACCINE) outcome was unknown.            Concomitant drugs not reported. The patient had two carpal tunnel surgeries in 2021. The patient did not recall contacting anyone about any problems or side effects that HUMIRA had on his carpal tunnel surgeries. Both surgeries went fine and physician did an excellent job. He just experienced the normal discomfort from any surgery. He was advised by physiotherapy on what stretched to do. He did the recommended stretched at home. He had good and bad days, since he had taken weekly injection of HUMIRA. He was happy to say that he had good days than bad as his psoriatic arthritis went. She did take Covid vaccine, only arm tender sore at injection site of second vaccine. As of 16 Dec 2021, his both wrists were pretty much normal. It was unknown if patient was enrolled in a COVID-19 Vaccine Trial.  It was unknown if patient was enrolled in a COVID-19 Vaccine Trial.  This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company comment: This spontaneous case concerns a 66 year old male patient with concurrent conditions of psoriatic arthritis and rheumatoid arthritis , who experienced the unexpected serious (medically significant) events of Psoriatic arthropathy and Carpal tunnel syndrome, unknown days after receiving  the second dose of mRNA-1273 vaccine in the COVID-19 vaccination series. No information on exact dates of the events and mRNA-1273 vaccine , detailed clinical course, reports of relevant investigations and treatment details was available in the report. The events were resolving. Concurrent condition of psoriatic arthritis could be confounding for the event Psoriatic arthropathy. Concurrent conditions of psoriatic arthritis and rheumatoid arthritis could be risk factors for Carpal tunnel syndrome. The benefit-risk relationship of mRNA-1273 is not affected by this report.   Most recent FOLLOW-UP information incorporated above includes: On 22-Dec-2021: Follow up received and updated event information.; Sender's Comments: This spontaneous case concerns a 66 year old male patient with concurrent conditions of psoriatic arthritis and rheumatoid arthritis , who experienced the unexpected serious (medically significant) events of Psoriatic arthropathy and Carpal tunnel syndrome, unknown days after receiving  the second dose of mRNA-1273 vaccine in the COVID-19 vaccination series. No information on exact dates of the events and mRNA-1273 vaccine , detailed clinical course, reports of relevant investigations and treatment details was available in the report. The events were resolving. Concurrent condition of psoriatic arthritis could be confounding for the event Psoriatic arthropathy. Concurrent conditions of psoriatic arthritis and rheumatoid arthritis could be risk factors for Carpal tunnel syndrome. The benefit-risk relationship of mRNA-1273 is not affected by this report.