Sex: F
Vaccine: VARZOS
Symptoms: Peripheral swelling, Pruritus, Pyrexia, Scab, Vomiting
Clinical narrative: thrush / felt like a terrible poison ivy on her back, arms, shoulders to her elbow on both sides of her body / thrush went all the way up to the hairline and to her butt; soreness when she would roll over when sleeping; scabs; swelling of the arm; couldn't sleep; sore arm; digging at the thrush because it felt like sand under the skin / itch; was miserable/  felt like sand under the skin; terrible poison ivy on back, arm, shoulder to elbow on both side of body; ill with COPD; coughing badly; illness; fever; throwing up; diarrhea; This case was reported by a consumer via call center representative and described the occurrence of chronic obstructive pulmonary disease in a 78-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Previously administered products included Zostavax (received vaccine years ago). Concomitant products included methylprednisolone.   In September 2020, the patient received the 1st dose of Shingrix. In December 2020, between 2 and 4 months after receiving Shingrix, the patient experienced chronic obstructive pulmonary disease, cough and illness. On an unknown date, the patient experienced thrush, general body pain, scab, fever, vomiting, diarrhea, swelling arm, difficulty sleeping, pain in arm, pruritus, feeling miserable and poison ivy rash. On an unknown date, the outcome of the chronic obstructive pulmonary disease, cough, illness, thrush and scab were not recovered/not resolved and the outcome of the general body pain, fever, vomiting, diarrhea, swelling arm, difficulty sleeping, pain in arm, pruritus, feeling miserable and poison ivy rash were recovered/resolved.  It was unknown if the reporter considered the chronic obstructive pulmonary disease, cough, illness, thrush, general body pain, scab, fever, vomiting, diarrhea, swelling arm, difficulty sleeping, pain in arm, pruritus, feeling miserable and poison ivy rash to be related to Shingrix.  Additional details were provided as follows: The reporter was reported for herself. The age at vaccination was not reported. The patient received 1st dose of Shingrix in the left arm. The reporter stated that, few days after vaccination, had sore arm, swelling of the arm and soreness when would roll over when sleeping. A few days later experienced diarrhea, throwing up, fever which lasted 3 days. The patient described as thrush which felt like a terrible poison ivy on her back, arms, shoulders to her elbow on both sides of her body. The patient would wake up at night digging at the thrush because it felt like sand under the skin and would dig the head off and still had scabs where she dug so badly. The thrush went all the way up to the hairline and to her butt where the patient sat and was miserable. The reporter stated that, the only symptom that remains today was thrush. The reporter did mention at the end of the conversation that she was currently ill with COPD and she was coughing badly.  She said that her illness started 2 weeks ago and it was a seasonal thing for her. The physician prescribed medication for the itch because she could not sleep. The patient was advised by her physician to not get the second dose of Shingrix. The reporter consented to follow up.