Age: 70.0
Sex: M
Vaccine: COVID19
Symptoms: Rectal examination, Red blood cell sedimentation rate, Sensory loss, Very low density lipoprotein
Clinical narrative: Post herpetic neuralgia - severe; Left arm got little numb; Lymoh node swelling; Shingles/pain swelling and rash left axilla consistent with herpes zoster; Lost feeling underneath the arm; This spontaneous case was reported by a consumer and describes the occurrence of HERPES ZOSTER (Shingles/pain swelling and rash left axilla consistent with herpes zoster), SENSORY LOSS (Lost feeling underneath the arm), POST HERPETIC NEURALGIA (Post herpetic neuralgia - severe), HYPOAESTHESIA (Left arm got little numb) and LYMPHADENOPATHY (Lymoh node swelling) in a 70-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 031L20A) for COVID-19 vaccination.     The patient's past medical history included Herpes zoster, Smoker, Dyspnea exertional, Abdominal pain, Hematuria, Lumbar strain, Kidney function abnormal (Low kidney function), Kidney stones, Constipation, Chronic cough, Back pain, Surgery (Distal reinsertion of ruptured biceps tendon), Septoplasty and Tonsillectomy. Previously administered products included for an unreported indication: ZOSTER on 08-Dec-2012, INFLUENZA (Series 1) on 22-Sep-2015, PNEUMOCOCCAL POLYSACCHARIDE VACCINE on 08-Dec-2015, INFLUENZA (Series 2) on 19-Sep-2017, PNEUMOCOCCAL CONJUGATE VACCINE on 19-Dec-2017, INFLUENZA (Series 3) on 21-Dec-2018, INFLUENZA (Series 4) on 24-Dec-2019 and INFLUENZA (Series 5) on 14-Sep-2020. Family history included Hypertension (Sister), Ovarian cancer (Daughter) and Type 2 diabetes mellitus (Mother, Father). Concurrent medical conditions included Acid reflux (esophageal), Enlarged prostate (benign), Arthritis, COPD, Dysphagia, Eczema, Hepatomegaly, Hyperlipidemia, Hypertension, Temporal arteritis, Temporomandibular joint arthralgia (Temporomandibular joint pain), Type 2 diabetes mellitus (Type 2 diabetes mellitus with hyperlipidemia), Drug allergy (Cephalexin Monohydrate TABS caused hives) since 21-Dec-2018, Drug allergy (Tricor TABS caused headache) and Alcohol use (Reports drinking 20 drinks per week.). Concomitant products included AMLODIPINE BESYLATE, ACETYLSALICYLIC ACID (ASPIRIN (E.C.)), FLUOCINOLONE ACETONIDE, GLIPIZIDE, METFORMIN HCL, METOPROLOL TARTRATE, PANTOPRAZOLE SODIUM, PRAVASTATIN SODIUM, PREDNISONE and SODIUM FLUORIDE (PREVIDENT 5000 BOOSTER) for an unknown indication.    On 11-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 12-Feb-2021, the patient experienced HERPES ZOSTER (Shingles/pain swelling and rash left axilla consistent with herpes zoster) and SENSORY LOSS (Lost feeling underneath the arm). 12-Feb-2021, the patient experienced HYPOAESTHESIA (Left arm got little numb) and LYMPHADENOPATHY (Lymoh node swelling). On an unknown date, the patient experienced POST HERPETIC NEURALGIA (Post herpetic neuralgia - severe). The patient was treated with VALACICLOVIR HYDROCHLORIDE (VALACYCLOVIR HCL) (oral) for Shingles, at a dose of 1 gram three times a day and GABAPENTINE at a dose of 1 dosage form three times a day. On 05-Apr-2021, HERPES ZOSTER (Shingles/pain swelling and rash left axilla consistent with herpes zoster) had resolved with sequelae. At the time of the report, SENSORY LOSS (Lost feeling underneath the arm), HYPOAESTHESIA (Left arm got little numb) and LYMPHADENOPATHY (Lymoh node swelling) outcome was unknown and POST HERPETIC NEURALGIA (Post herpetic neuralgia - severe) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 22-Feb-2021, Alanine aminotransferase: 24 (normal) normal. On 22-Feb-2021, Albumin globulin ratio: 2 (normal) normal. On 22-Feb-2021, Anion gap: 12 (Inconclusive) inconclusive. On 22-Feb-2021, Aspartate aminotransferase (4-40 U/L): 19 U/L (normal) normal. On 22-Feb-2021, Blood albumin (3.5-5.2 gram per decilitre): 4.5 gram per decilitre (normal) normal. On 22-Feb-2021, Blood alkaline phosphatase (40-130 U/L): 34 U/L (Low) low. On 22-Feb-2021, Blood bilirubin (0.1-1.0 milligram per decilitre): 0.6 milligram per decilitre (normal) normal. On 22-Feb-2021, Blood calcium (8.6-10.5 milligram per decilitre): 10 milligram per decilitre (normal) normal. On 22-Feb-2021, Blood chloride (96-108 millimole per litre): 98 millimole per litre (normal) normal. On 22-Feb-2021, Blood cholesterol (0-199 mg/dl): 177 mg/dl (normal) Normal. On 22-Feb-2021, Blood creatinine (0.5-1.2 milligram per decilitre): 1.1 milligram per decilitre (normal) normal. On 22-Feb-2021, Blood glucose (65-99 mg/dl): 137 mg/dl (High) Abnormal. On 22-Feb-2021, Blood osmolarity (253-285): 267 (normal) normal. On 22-Feb-2021, Blood potassium (3.3-5.3 millimole per litre): 4.6 millimole per litre (normal) normal. On 22-Feb-2021, Blood sodium (133-145 millimole per litre): 137 millimole per litre (normal) normal. On 22-Feb-2021, Blood triglycerides (0-150 mg/dl): 332 mg/dl (High) Abnormal. On 22-Feb-2021, Blood urea (8-23 milligram per decilitre): 12 milligram per decilitre (normal) normal. On 22-Feb-2021, Carbon dioxide (22-32 millimole per litre): 28 millimole per litre (normal) normal. On 22-Feb-2021, Globulin (1.4-4.8 gram per decilitre): 3 gram per decilitre (normal) normal. On 22-Feb-2021, Glycosylated haemoglobin (4.3-6.1 %): 7.2 % (High) high. On 22-Feb-2021, High density lipoprotein (40-80 mg/dl): 38 mg/dl (Low) Abnormal. On 22-Feb-2021, Low density lipoprotein (0-100 mg/dl): 73 mg/dl (normal) Normal. On 22-Feb-2021, Non-high-density lipoprotein cholesterol (0-130 mg/dl): 140 mg/dl (High) Abnormal. On 22-Feb-2021, Protein total (6.2-8.2 gram per decilitre): 7.5 gram per decilitre (normal) normal. On 22-Feb-2021, Red blood cell sedimentation rate (0-20 mm/hr): 30 mm/hr (High) Abnormal. On 22-Feb-2021, Very low density lipoprotein (5-40 mg/dl): 66 mg/dl (High) Abnormal. On an unknown date, Hepatitis C antibody: positive (Positive) positive. On an unknown date, Prostatic specific antigen (0.0-4.0 nanogram per millliiter): 0.8 nanogram per millliiter (normal) normal. On an unknown date, Rectal examination: positive (Positive) positive.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   Most recent FOLLOW-UP information incorporated above includes: On 06-May-2021: Patient demographic detail was updated On 21-May-2021: Added medical history, laboratory tests, De, an re challenge fields, concomitant medications and treatment medications The outcome of the event (Herpes zoster) changed (Unknown to Recovered/resolved with sequence), Herpes zoster event verbatim updated. On 13-Jul-2021: Follow-up information received on 13-Jul-2021 contains no new information.