Age: 61.0
Sex: F
Vaccine: COVID19
Symptoms: Cytokine storm, Inflammation, Myocardial infarction
Clinical narrative: heart attack; Cytokine storm; Inflammation; This spontaneous case was reported by a consumer and describes the occurrence of MYOCARDIAL INFARCTION (heart attack) and CYTOKINE STORM (Cytokine storm) in a 61-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced MYOCARDIAL INFARCTION (heart attack) (seriousness criteria death and medically significant), CYTOKINE STORM (Cytokine storm) (seriousness criterion medically significant) and INFLAMMATION (Inflammation). The patient died on an unknown date. The reported cause of death was Heart attack. It is unknown if an autopsy was performed. At the time of death, CYTOKINE STORM (Cytokine storm) and INFLAMMATION (Inflammation) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       No Concomitant and Treatment Drug was provided by reporter.   This case was identified as part of a retrospective clean-up activity where certain emails received in the Moderna mailbox were missed to be booked-in.  Company comment-This spontaneous case concerns a female patient aged 61 years with no medical history reported, who experienced the fatal serious (medically significant) unexpected AESI of Myocardial infarction and unexpected serious (medically significant) AESI of Cytokine storm which occurred in the context of mRNA-1273 vaccination. Latency cannot be assessed since vaccination date was not disclosed. No further information on risk factors, concurrent illness, detailed clinical course, investigations, treatment of the event and details pertaining to doses was available in the report. The reported cause of death was unknown. Patient died on an unknown date. It is unknown if an autopsy was performed. The events Myocardial infarction and Cytokine storm could have led to the fatal outcome. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed as per medical judgement.; Sender's Comments: This spontaneous case concerns a female patient aged 61 years with no medical history reported, who experienced the fatal serious (medically significant) unexpected AESI of Myocardial infarction and unexpected serious (medically significant) AESI of Cytokine storm which occurred in the context of mRNA-1273 vaccination. Latency cannot be assessed since vaccination date was not disclosed. No further information on risk factors, concurrent illness, detailed clinical course, investigations, treatment of the event and details pertaining to doses was available in the report. The reported cause of death was unknown. Patient died on an unknown date. It is unknown if an autopsy was performed. The events Myocardial infarction and Cytokine storm could have led to the fatal outcome. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report. Event seriousness assessed as per medical judgement.; Reported Cause(s) of Death: Heart attack