Age: 61.0
Sex: F
Vaccine: COVID19
Symptoms: Abdominal pain, Polyarteritis nodosa
Clinical narrative: diagnosed with polyarteritis nodosa; acute abdominal pain; This spontaneous case was reported by a pharmacist and describes the occurrence of POLYARTERITIS NODOSA (diagnosed with polyarteritis nodosa) and ABDOMINAL PAIN (acute abdominal pain) in a 62-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 065F21A, 029L20A and 012L20A) for COVID-19 vaccination.     No Medical History information was reported.   On 12-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 10-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 18-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 26-Jan-2022, the patient experienced ABDOMINAL PAIN (acute abdominal pain) (seriousness criterion hospitalization). On 27-Jan-2022, the patient experienced POLYARTERITIS NODOSA (diagnosed with polyarteritis nodosa) (seriousness criteria hospitalization and medically significant). The patient was hospitalized from 27-Jan-2022 to 02-Feb-2022 due to ABDOMINAL PAIN and POLYARTERITIS NODOSA. At the time of the report, POLYARTERITIS NODOSA (diagnosed with polyarteritis nodosa) and ABDOMINAL PAIN (acute abdominal pain) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant and treatment medication was reported by patient.  Patient reported that she had taken 2 doses and booster dose of the Moderna Covid-19 Vaccine. Patient reported that she experienced acute abdominal pain on 26 Jan 2022 and was hospitalized on 27 Jan 2022 for 6 days, patient diagnosed with polyarteritis nodosa on 27 Jan 2022. Patient received a second opinion after being discharged from the hospital on 2 Feb 2022 that also concluded she had polyarteritis nodosa.  Company comment: This case concerns a 22-year-old, female patient with no relevant medical history, who experienced the unexpected serious events of Acute Abdominal Pain and Polyarteritis Nodosa. The events occurred approximately 2 month 9 days after the booster dose of mRNA-1273 (Moderna covid-19 vaccine). Patient began experiencing acute abdominal pain, hospitalized for 6 days, and diagnosed with polyarteritis nodosa. The rechallenge was not applicable as events occurred after a booster dose. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.; Sender's Comments: This case concerns a 22-year-old, female patient with no relevant medical history, who experienced the unexpected serious events of Acute Abdominal Pain and Polyarteritis Nodosa. The events occurred approximately 2 month 9 days after the booster dose of mRNA-1273 (Moderna covid-19 vaccine). Patient began experiencing acute abdominal pain, hospitalized for 6 days, and diagnosed with polyarteritis nodosa. The rechallenge was not applicable as events occurred after a booster dose. The benefit-risk relationship of mRNA-1273 (Moderna covid-19 vaccine) is not affected by this report.