Age: 12.0
Sex: M
Vaccine: COVID19
Symptoms: Aphasia, Arteriovenous malformation, Blood pressure increased, Blood pressure measurement, Cerebrovascular accident
Clinical narrative: stroke; a rupture of an arteriovenous malformation (AVM) in his brain; an increase in the patient's blood pressure; The patient lost his ability to walk, talk, and eat; The patient lost his ability to walk, talk, and eat; The patient lost his ability to walk, talk, and eat; can't use his right arm; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the parent.  A 12-year-old male patient received bnt162b2 (BNT162B2), on 15Jun2021 as dose 2, single (Batch/Lot number: unknown) at the age of 12 years for covid-19 immunisation. The patient's relevant medical history included: "AVM discovered at the time of the event and subsequently surgically removed" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, COVID 19, Pfizer-BioNTech, lot unknown), for COVID-19 immunization. The following information was reported: FEEDING DISORDER (hospitalization, disability, life threatening), GAIT INABILITY (hospitalization, disability, life threatening), APHASIA (hospitalization, disability, life threatening) all with onset 15Jun2021, outcome "recovered with sequelae" and all described as "The patient lost his ability to walk, talk, and eat"; ARTERIOVENOUS MALFORMATION (hospitalization, disability, medically significant, life threatening) with onset 15Jun2021, outcome "recovered with sequelae", described as "a rupture of an arteriovenous malformation (AVM) in his brain"; BLOOD PRESSURE INCREASED (hospitalization, disability, life threatening) with onset 15Jun2021, outcome "recovered with sequelae", described as "an increase in the patient's blood pressure"; LIMB DISCOMFORT (hospitalization, disability, life threatening) with onset 15Jun2021, outcome "recovered with sequelae", described as "can't use his right arm"; CEREBROVASCULAR ACCIDENT (hospitalization, disability, medically significant, life threatening) with onset 15Jun2021, outcome "recovered with sequelae", described as "stroke". The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (15Jun2021) increase, notes: increase in the patient's blood pressure; Weight: (15Jun2021) Unknown results, notes: the patient was in the 5th percentile for his body weight. Therapeutic measures were taken as a result of cerebrovascular accident, arteriovenous malformation, blood pressure increased, feeding disorder, gait inability, aphasia, limb discomfort.  Clinical information: About 12 hours after receiving his 2nd dose, the patient experienced a stroke due to a rupture of an arteriovenous malformation (AVM) in his brain. The rupture was caused by an increase in the patient's blood pressure in reaction to the vaccine. The patient was 12 years old at the time. The vaccine dose administered was the full dose recommended for his age which was the same dose given to adults. However, the patient was in the 5th percentile for his body weight. The patient lost his ability to walk, talk, and eat. He has partially recovered but is now disabled and can't use his right arm. The reporter of this event is the child's father. He stated this event was reported to Pfizer in 2021 and his family has been contacted for follow-up information in relation to the original report. Adverse event start date: 15Jun2021.  Ae resulted in: [Hospitalization, Life threatening illness (immediate risk of death from the event), Disability or permanent damage]. If patient recovered: Recovered with lasting effects. If treatment ae: Yes. Ae treatment: Emergency surgery to stop the bleeding in the brain. Unknown if covid prior vaccination or if covid tested post vaccination. Other medical history: AVM discovered at the time of the event and subsequently surgically removed.   The information on the batch/lot number for bnt162b2 has been requested and will be submitted if and when received.