Age: 31.0
Sex: M
Vaccine: COVID19
Symptoms: COVID-19, Hepatic enzyme increased, Liver function test, Vaccination failure
Clinical narrative: COVID Symptoms 5 months after 2nd primary shot; Liver enzymes went up post COVID symptoms 5 months after 2nd primary shot; COVID Symptoms 5 months after 2nd primary shot; This spontaneous case was reported by a patient family member or friend and describes the occurrence of COVID-19 (COVID Symptoms 5 months after 2nd primary shot), HEPATIC ENZYME INCREASED (Liver enzymes went up post COVID symptoms 5 months after 2nd primary shot) and VACCINATION FAILURE (COVID Symptoms 5 months after 2nd primary shot) in a 31-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     Concurrent medical conditions included Cerebral palsy and Speech disorder. Concomitant products included LITHIUM for an unknown indication.   On 15-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 13-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In June 2021, the patient experienced COVID-19 (COVID Symptoms 5 months after 2nd primary shot), HEPATIC ENZYME INCREASED (Liver enzymes went up post COVID symptoms 5 months after 2nd primary shot) and VACCINATION FAILURE (COVID Symptoms 5 months after 2nd primary shot). In July 2021, COVID-19 (COVID Symptoms 5 months after 2nd primary shot) and HEPATIC ENZYME INCREASED (Liver enzymes went up post COVID symptoms 5 months after 2nd primary shot) had resolved. At the time of the report, VACCINATION FAILURE (COVID Symptoms 5 months after 2nd primary shot) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In June 2021, Liver function test: Liver enzymes went up. In July 2021, Liver function test: Liver enzymes back down.         It was reported that during the last week of Jun-2021 or first week of Jul-2021, patient  had COVID Symptoms, but never did the PCR test. Patient Llver enzymes went up after he got sick and then back down a month later.On 23-Nov-2021, patient received the 1st monovalent booster dose of Moderna COVID-19 vaccineOn 23-Nov-2022, patient received the Bivalent booster dose of Moderna.The patient was scheduled to receive Botox injections in his legs, on 01-Dec-2022. The pharmacist told them to wait a while before getting Botox.No treatment medications were reported.  Company comment: This is a spontaneous case concerning 31 years old male, with no relevant medical history, who experienced the unexpected non serious event of vaccination failure (reported as COVID Symptoms 5 months after 2nd primary shot), which occurred unspecified days after second dose of mRNA-1273 vaccine. Additionally non serious event Covid-19, hepatic enzyme increased is also reported. Patient mother reported that her son had Covid symptoms, but never did PCR test and liver enzymes went up and after patient got sick and became normal after a month later. At the time of reporting outcome of the event is unknown. No further information on clinical course, lab data, treatment received. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning 31 years old male, with no relevant medical history, who experienced the unexpected non serious event of vaccination failure (reported as COVID Symptoms 5 months after 2nd primary shot), which occurred unspecified days after second dose of mRNA-1273 vaccine. Additionally non serious event Covid-19, hepatic enzyme increased is also reported. Patient mother reported that her son had Covid symptoms, but never did PCR test and liver enzymes went up and after patient got sick and became normal after a month later. At the time of reporting outcome of the event is unknown. No further information on clinical course, lab data, treatment received. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.