Age: 59.0
Sex: F
Vaccine: COVID19
Symptoms: Pain, Skin discolouration, Tendon disorder, Weight
Clinical narrative: Severe pain to the right upper buttocks and hamstring; Bilateral ankle swelling; Shortness of breath; Right leg colour change; Right leg weak from muscle atrophy; Pain with sitting and climbing stairs; Tendinopathy; Hamstring pain severe; This spontaneous case was reported by a nurse and describes the occurrence of MUSCULOSKELETAL PAIN (Severe pain to the right upper buttocks and hamstring), JOINT SWELLING (Bilateral ankle swelling), DYSPNOEA (Shortness of breath), SKIN DISCOLOURATION (Right leg colour change) and MUSCLE ATROPHY (Right leg weak from muscle atrophy) in a 59-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 036A21A and 010M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Hives, Migraine since 01-Jan-2005, Osteoporosis since 01-Jan-2000 and Anaphylaxis. Concomitant products included VITAMINS NOS (MVI [VITAMINS NOS]) for Supplementation therapy, LORATADINE (CLARITINE) from 02-Mar-2021 to an unknown date and RANITIDINE HYDROCHLORIDE (ZANTAC) for an unknown indication.   On 03-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 03-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced MUSCULOSKELETAL PAIN (Severe pain to the right upper buttocks and hamstring), JOINT SWELLING (Bilateral ankle swelling), DYSPNOEA (Shortness of breath), SKIN DISCOLOURATION (Right leg colour change), MUSCLE ATROPHY (Right leg weak from muscle atrophy), PAIN (Pain with sitting and climbing stairs), TENDON DISORDER (Tendinopathy) and MYALGIA (Hamstring pain severe). The patient was treated with GABAPENTIN ongoing since an unknown date for Adverse event, at a dose of 100 milligram once a day and PARACETAMOL (TYLENOL) ongoing since an unknown date for Adverse event, at a dose of UNK UNK, qd. At the time of the report, MUSCULOSKELETAL PAIN (Severe pain to the right upper buttocks and hamstring), JOINT SWELLING (Bilateral ankle swelling), SKIN DISCOLOURATION (Right leg colour change), MUSCLE ATROPHY (Right leg weak from muscle atrophy), TENDON DISORDER (Tendinopathy) and MYALGIA (Hamstring pain severe) outcome was unknown, DYSPNOEA (Shortness of breath) was resolving and PAIN (Pain with sitting and climbing stairs) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Weight: loss (Low) 10 lb weight loss.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   On 12-Jan-2012, the patient started NSAIDs treatment for hives.  The patient went to orthopedic urgent care and was treated for tendinopathy. The patient went for physical therapy for two to three times per week in the past three months. The patient was home care nurse and since past seven months was resting at home.   This case was linked to MOD-2021-294480 (Patient Link).