chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 17.0
Sex: M
Vaccine: HEPA, TYP, YF
Symptoms: Syncope
Clinical narrative: Sitting in chair, tipped to side after receiving 3 vaccines, fainted against a table. Staff moved him to the floor and used ammonia capsule to rouse.  Roused easily. No injury incurred. Vitals stable at 15 minute check. Departed with parent.
Age: 21.0
Sex: F
Vaccine: RAB
Symptoms: Dizziness, Feeling hot, Injection site warmth, Nausea, Oedema peripheral
Clinical narrative: Received Shot at 8:47 AM. Went running after noon. Began to feel nauseated and light headed and hot. Went home and by that time arm was swollen and hot over injection site. Had localized hives in that area as well. Still felt nauseated and light headed and hot. Took Benadryl and went to sleep when she awoke a little while later felt fine. Has been fine today 06/12/12.
Age: 21.0
Sex: M
Vaccine: HPV4, HPV4, HPV4
Symptoms: Gaze palsy, Syncope, Tremor
Clinical narrative: After receiving vaccine - pt fainted, tremors noted of bilateral upper & lower extremities with eyes rolling. No LOC. Recovered immediately.
Age: 38.0
Sex: F
Vaccine: HEP, MMR, TDAP
Symptoms: Erythema, Eye pruritus, Nasal congestion, Oedema peripheral, Throat irritation
Clinical narrative: Pt given Hep B MMR, Tdap at 930am. (NKDA) (No meds). No hx medical problems 950 am. Pt c/o red swollen area RA, throat itchy, c/o stuffiness, itchy eyes. BP 136/84 P-60 R-16 911 called 953 ambulance arrived. Pt transported.
Age: 2.0
Sex: M
Vaccine: DTAP, HEP, HIBV, PNC13
Symptoms: Crying, Rash
Clinical narrative: Approximately 15 minutes after receiving vaccines developed rash to face. Not itchy, no shortness of breath. Observed for additional 15 minutes for s/s anaphylaxis. Rash still present (pt. had been crying after shots) perhaps slightly increased. Given BENADRYL 12.5 mg orally here. Dad refused further doses.
Age: 1.24
Sex: M
Vaccine: MMR, VARCEL
Symptoms: Rash generalised
Clinical narrative: Rash generalized. Tx: BENADRYL.
Age: 61.0
Sex: F
Vaccine: VARZOS
Symptoms: Rash vesicular
Clinical narrative: Patient reported shingles DX in April 2012; consult w/ her employer's occupational health clinic on 5/14/12 & ZOSTAVAX vaccine ordered for patient; received ZOSTAVAX vaccine on 5/18/12; Developed chicken pox rash on 5/29/12. Rash appears on face, trunk, arms & legs.
Age: 0.87
Sex: M
Vaccine: DTAPIPVHIB, PNC13
Symptoms: Vomiting
Clinical narrative: Two bouts of vomiting.
Age: 0.39
Sex: M
Vaccine: DTAPIPVHIB, PNC13, RV1
Symptoms: Abnormal behaviour, Lethargy, Pyrexia, Screaming, Tremor
Clinical narrative: Child was screaming for > 6-8 hours. Parents describe child lethargic and "acting out-of-it" for 1 week after vaccines. Was "shaking" for first day but no real seizure noted. Fever for 2 days after vaccines.
Age: 4.0
Sex: M
Vaccine: DTAPIPV, PNC13
Symptoms: Erythema, Pruritus, Rash, Urticaria
Clinical narrative: RASH, HIVES, ITICHING, REDNESS. PATIENT WAS GIVEN A DOSE OF BENADRYL AND CHILD WAS ABLE TO RECOVER.
Age: 32.0
Sex: F
Vaccine: TDAP
Symptoms: Dizziness, Headache, Nausea, Pain
Clinical narrative: Aching, Headache, Nausea, Dizziness.
Age: 53.0
Sex: F
Vaccine: PER
Symptoms: Urticaria
Clinical narrative: Hives began appearing on my arms, legs, torso. This is the 2nd time I have broken out in hives after a vaccination. The first time was Nov 4, 2011. I had them until March 2012. I though they cld have been brought on by vaccine. Dr couldn't prove or discount.
Age: 1.12
Sex: F
Vaccine: PNC13, VARCEL
Symptoms: Altered state of consciousness, Breath holding, Crying, Cyanosis, Dyspnoea
Clinical narrative: Patient was unable to catch breath following second IZ (was given VZV, then PCV13), she was observed turning blue in the face, her eyes rolled back, she arched her back and contracted her arms, was very stiff and unresponsive for approximately 15 seconds. She started crying and returned to normal consciousness and color within 2 minutes. Probably breath-holding spell.
Age: 1.12
Sex: F
Vaccine: PNC13, VARCEL
Symptoms: Extremity contracture, Gaze palsy, Musculoskeletal stiffness, Opisthotonus, Unresponsive to stimuli
Clinical narrative: Patient was unable to catch breath following second IZ (was given VZV, then PCV13), she was observed turning blue in the face, her eyes rolled back, she arched her back and contracted her arms, was very stiff and unresponsive for approximately 15 seconds. She started crying and returned to normal consciousness and color within 2 minutes. Probably breath-holding spell.
Age: 1.03
Sex: M
Vaccine: PNC13, VARCEL
Symptoms: Convulsion, Meningitis streptococcal
Clinical narrative: Patient developed seizures that were caused by streptococcal meningitis, 19A.
Age: 17.0
Sex: F
Vaccine: HPV4, TDAP, HPV4, TDAP
Symptoms: Rash macular, Rash pruritic
Clinical narrative: Pruritic macular rash on all extremities; resolved with Benadryl over 3 days.
Age: 66.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Injection site and area surrounding the site red & swollen. Patient also saying area is painful. The patient was prescribed steroids by her doctor.
Age: 17.0
Sex: F
Vaccine: MNQ
Symptoms: Urticaria
Clinical narrative: Pt received MENACTRA vaccine and left the office. About 15 min. later mom called because pt started getting hives on her wrist & face. Mom brought her back. She was breathing fine. We gave her BENADRYL and instructions for anaphylaxis.
Age: 0.17
Sex: F
Vaccine: DTAPIPVHIB, RV5
Symptoms: Faeces discoloured, Mucous stools
Clinical narrative: Patients mother called office 5/25/12 to state 1 episode of mucousy stool occured on 5/24/12. Also stools went from a yellow to green color. Continues to have mucousy stools.
Age: 0.5
Sex: M
Vaccine: DTAPIPVHIB, FLU3, HEP, PNC13, RV5
Symptoms: Electroencephalogram abnormal, Infantile spasms
Clinical narrative: Child has Down's Syndrome. Child given vaccines 3/2/12. On 3/3/12 had first infantile spasm. Evaluated in ER 3/4/12 due to many spasms. Continues to have spasms (infantile spasms).
Age: 4.0
Sex: F
Vaccine: DTAPIPV, MMR
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling
Clinical narrative: Red swollen area about 4" across on (L) leg itchy.
Age: 71.0
Sex: F
Vaccine: VARZOS
Symptoms: Pruritus, Rash generalised
Clinical narrative: The first month following injection, pt complained of itching. Started taking BENADRYL. Then it progressed to transient linear rashes all over her body. Her primary MD gave her prednisone, but it is still occurring.
Age: 0.36
Sex: M
Vaccine: DTAP
Symptoms: Cough, Pyrexia, Rash erythematous, Rhinorrhoea, Vomiting
Clinical narrative: Severe vomiting, fever, cough, runny nose, red dots on skin.
Age: 0.18
Sex: F
Vaccine: DTAPIPVHIB, PNC13, RV1
Symptoms: Blood culture, CSF culture, Culture stool, Culture urine, Full blood count
Clinical narrative: Four days after vaccination, patient began vomiting, had bloody stools, diagnosed with intussusception, patient required surgery.
Age: 0.18
Sex: F
Vaccine: DTAPIPVHIB, PNC13, RV1
Symptoms: Haematochezia, Intussusception, Laboratory test, Surgery, Urine analysis
Clinical narrative: Four days after vaccination, patient began vomiting, had bloody stools, diagnosed with intussusception, patient required surgery.
Age: 0.18
Sex: F
Vaccine: DTAPIPVHIB, PNC13, RV1
Symptoms: Vomiting, X-ray
Clinical narrative: Four days after vaccination, patient began vomiting, had bloody stools, diagnosed with intussusception, patient required surgery.
Age: 76.0
Sex: F
Vaccine: VARZOS
Symptoms: Abnormal sensation in eye, Headache
Clinical narrative: Headaches from time administered up to 6 weeks; never had headaches before that. Took TYLENOL. Also pressure in the eyes.
Age: 74.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site pain
Clinical narrative: Erythema 3-4" at injection site painful/tender.
Age: 1.07
Sex: F
Vaccine: HEPA, MMR, PNC13, VARCEL
Symptoms: Injection site erythema, Injection site induration
Clinical narrative: Redness, hardness at injection site.
Age: 0.51
Sex: F
Vaccine: DTAPHEPBIP, PNC13, RV5
Symptoms: Asthenia, Blood culture negative, Chest X-ray normal, Hypotonia, Lethargy
Clinical narrative: Lethargic, paleness, weakness, vomiting. Extremely unresponsive and floppy. No fevering, no seizure.
Age: 0.51
Sex: F
Vaccine: DTAPHEPBIP, PNC13, RV5
Symptoms: Pallor, Unresponsive to stimuli, Urine analysis normal, Vomiting
Clinical narrative: Lethargic, paleness, weakness, vomiting. Extremely unresponsive and floppy. No fevering, no seizure.
Age: 23.0
Sex: F
Vaccine: HEP, TDAP
Symptoms: Abdominal pain, Diarrhoea, Migraine, Nausea, Vomiting
Clinical narrative: Started with abd pain (generalized), N/V/D in evening after vaccines. Continued the next day with progression to migraine. Seen in office and treated with NUBAIN IM and PHENERGAN IM.
Age: 0.09
Sex: F
Vaccine: HEP
Symptoms: Diarrhoea, Irritability, Vomiting
Clinical narrative: Irritability. Vomiting. Diarrhea. Began a few hours after Hep B vaccine.
Age: 35.0
Sex: F
Vaccine: HEP
Symptoms: Chest discomfort, Chest pain, Vaccine positive rechallenge
Clinical narrative: Patient explained that at doses 1, 2, and 3 she experienced chest tightness and pain 4 hrs after the vaccine was administered. The symptoms lasted 1 wk and resolved on its own.
Age: 22.0
Sex: F
Vaccine: MMR
Symptoms: Blood immunoglobulin G normal, Maternal exposure during pregnancy, Measles antibody negative
Clinical narrative: Pt. in 2nd trimester received vaccine. OB MD notified. Pt. brought in and counseled and will be closely monitored during pregnancy.
Age: 11.0
Sex: F
Vaccine: HPV2, HPV2
Symptoms: Altered state of consciousness, Dizziness, Fall
Clinical narrative: Triaged pt. (took vitals) then administered CERVARIX to (L) arm. Pt. was sitting at the time of shot. Pt. indicated her fear of needles so I instructed her to look away and stay seated. Once given I proceeded to fill out physical form. Pt. got dizzy and fell over about a minute after given. Vitals were taken and pt. was released once vitals were normal and Dr. released. Pt. did not fully pass out. Got dizzy and fell down.
Age: 11.0
Sex: F
Vaccine: HPV2, HPV2
Symptoms: Blood pressure decreased, Hypotonia, Immediate post-injection reaction, Loss of consciousness
Clinical narrative: Triaged pt. (took vitals) then administered CERVARIX to (L) arm. Pt. was sitting at the time of shot. Pt. indicated her fear of needles so I instructed her to look away and stay seated. Once given I proceeded to fill out physical form. Pt. got dizzy and fell over about a minute after given. Vitals were taken and pt. was released once vitals were normal and Dr. released. Pt. did not fully pass out. Got dizzy and fell down.
Sex: F
Vaccine: DTAPIPV, MMR, PNC13, VARCEL
Symptoms: Injection site erythema, Injection site swelling
Clinical narrative: Redness/swelling to leg (thigh). Tx: Cephalexin 250/5 10 ml q 12 hours x 10 days. Follow up 3 days.
Age: 67.0
Sex: M
Vaccine: VARZOS
Symptoms: Injection site haematoma, Injection site pain, Paraesthesia
Clinical narrative: Patient came to Pharmacy today stating he had noticed a bruise at the injection site with soreness starting about Saturday or Sunday (6/9 - 6/10). He also stated he had some tingling in left hand. Have not been get note to report to MD. No treatment other than patient taken a generic TYLENOL pm at night.
Age: 69.0
Sex: M
Vaccine: VARZOS
Symptoms: Arthralgia, Chills, Diarrhoea, Headache, Hyperhidrosis
Clinical narrative: 6 AM - 10 AM Golfed on 6/9/12 then around 10:15 A Pt. started feeling ill which lasted approx. 30 seconds. One hour later the pt. experienced the same feeling. At 1 PM pt. went to bed shivering w/ headache. Used heating pad and covers for relief. Pt. slept from 1 PM to 1 AM. Woke up wet w/ sweat. On 6-10-12 pt. woke up at 8 AM and felt like was recovering from flu all day. Muscle aches, joint aches, dull headache. On 6-11-12, 6 AM diarrhea, feverish and achy. Btn 10A - 11A had complete recovery.
Age: 69.0
Sex: M
Vaccine: VARZOS
Symptoms: Influenza like illness, Malaise, Myalgia, Pain, Pyrexia
Clinical narrative: 6 AM - 10 AM Golfed on 6/9/12 then around 10:15 A Pt. started feeling ill which lasted approx. 30 seconds. One hour later the pt. experienced the same feeling. At 1 PM pt. went to bed shivering w/ headache. Used heating pad and covers for relief. Pt. slept from 1 PM to 1 AM. Woke up wet w/ sweat. On 6-10-12 pt. woke up at 8 AM and felt like was recovering from flu all day. Muscle aches, joint aches, dull headache. On 6-11-12, 6 AM diarrhea, feverish and achy. Btn 10A - 11A had complete recovery.
Age: 0.6
Sex: M
Vaccine: HEPA, MMR, PNC, VARCEL
Symptoms: Injection site rash
Clinical narrative: Fine rash around injection sites on both thighs the size of a silver dollar per mother's report.
Age: 62.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Body temperature increased, Cellulitis, Rash, Skin warm
Clinical narrative: APN called 6/11 stating patient developed severe cellulitis in vaccinated arm - pt. started on antibiotics.
Age: 62.0
Sex: F
Vaccine: VARZOS, VARZOS
Symptoms: Cellulitis
Clinical narrative: APN called 6/11 stating patient developed severe cellulitis in vaccinated arm - pt. started on antibiotics.
Age: 1.04
Sex: M
Vaccine: HIBV, MEN, PPV
Symptoms: Injection site rash
Clinical narrative: Skin rash on legs at site of injections.
Age: 0.86
Sex: F
Vaccine: 6VAX-F, DTAP
Symptoms: Injection site erythema, Injection site mass, Injection site pain, Injection site warmth, Pyrexia
Clinical narrative: Red lump at the injection site that is sore to the touch and is hot. Running fever off and on for a couple of days. Lump is about the size of a quarter.
Age: 21.0
Sex: M
Vaccine: SMALL
Symptoms: Injection site vesicles, Sunburn
Clinical narrative: Pt sunburned when attempting to "dry out" vaccine site 12 cm blister.
Age: 13.0
Sex: M
Vaccine: HEPA, HPV4
Symptoms: Lymphadenopathy
Clinical narrative: Unilateral cervical lymphadenopathy 24 hrs after HPV vaccine.
Age: 58.0
Sex: M
Vaccine: VARZOS
Symptoms: Contusion
Clinical narrative: Patient's spouse states patient had bruising and what looks like a possible infection. PCP was contacted on 6/6/12 and he stated he had no knowledge of the situation.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Colitis, Condition aggravated, Crohn's disease, Fatigue, Menstruation irregular
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Pain
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Abdominal pain, Abdominal pain lower, Abdominal tenderness, Blood chloride increased, Colitis
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Computerised tomogram abdomen abnormal, Condition aggravated, Constipation, Crohn's disease, Decreased appetite
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Fatigue, Haematocrit decreased, Haemoglobin decreased, Lymphocyte percentage increased, Menstruation irregular
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Monocyte percentage increased, Nausea, Neutrophil percentage decreased, Pain, Pyrexia
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 22.0
Sex: F
Vaccine: HPV4, TDAP, HPV4
Symptoms: Red blood cell count decreased, Vomiting, White blood cell count normal
Clinical narrative: Was seen by specialist due to colitis flare and was told symptoms started after GARDASIL was given. Also had fatigue, body aches, irregular menses and Crohns disease flare. GARDASIL was given in 2007.
Age: 17.0
Sex: F
Vaccine: MNQ, TDAP
Symptoms: Headache, Pain, Petechiae, Rash, Vomiting
Clinical narrative: Pt woke at 5AM vomiting, body aches, headache, rash on face - petechiae.
Age: 30.0
Sex: F
Vaccine: TDAP
Symptoms: Arthralgia, Injection site erythema, Injection site pain, Local reaction, Malaise
Clinical narrative: Pt developed generalised achiness with joint pains and c/o "not feeling well". Also had local reaction with erythema & tenderness at site of inj. S/S subsided after a few days (5-7).
Age: 30.0
Sex: F
Vaccine: TDAP
Symptoms: Pain
Clinical narrative: Pt developed generalised achiness with joint pains and c/o "not feeling well". Also had local reaction with erythema & tenderness at site of inj. S/S subsided after a few days (5-7).
Age: 35.0
Sex: M
Vaccine: TDAP
Symptoms: Arthralgia, Body temperature increased, Pain
Clinical narrative: Pt c/o generalised achiness & jt pains 2 days after inj Tdap. No local reaction at site of injection. Temp = 99.4 F. S/S subsided after a few days.
Age: 7.0
Sex: F
Vaccine: FLUX
Symptoms: Death
Clinical narrative: This social media report (initial receipt: 04-Jun-2012) concerns a 7-year-old female patient. On ??-Dec-2011 the patient received her fatal dose of flu vaccine (manufacturer, brand name and batch number were not reported) and was pronounced dead about 92 hours later on 06-Dec-2011. The cause of death was not reported.
Age: 62.0
Sex: M
Vaccine: VARZOS
Symptoms: Burning sensation, Pruritus, Rash, Rash erythematous, Skin exfoliation
Clinical narrative: See attached sheet. April 20, 2012 Vaccine administered at pharmacy. April 27, 2012 Began noticing a rash on three places on my scalp that was itching and burning. After attempting to treat it with Neosporin Cream for approximately one week I called the doctor and was told the nurse could look at the spots on May 9th. May 9th 2012 Two nurses at the clinic looked at the red spots and recommended I apply an 'anti itch cream' for the next week and then call for an appointment if the spots did not clear up. I informed the nurses that I have received the Zoster vaccine on April 20 and ask if that could be the cause. I purchased 2% Diphenhydramine Hydrochloride with .01% Zinc Acetate at the pharmacy and begin using the next day. May 17, 2012 Red spits had not improved. The skin at one of the spots would also peel and continues to do so. Doctor could not see me due to his schedule and my schedule for the next two weeks and I was told to continue using the anti itch cream and an appointment was made for June 5. I stopped using the cream on June 2. June 5, 2012 Doctor looked at the red rash spots that had not improved and I ask him if the Zoster Vaccine I had received could be causing the rash. He did not comment on the vaccine but told me not to use any shampoo on my hair, keep the sun off my head and just wash with regular water for the next two weeks. If the rash had not cleared up by then he would set me an appointment with a dermatologist. June 10, 2012 The rash had not improved so I stopped by pharmacy an ask immunization pharmacist what he thought about the rash reaction. He recommended that I complete a VAERS and report the adverse event since it could be caused by the ZOSTAVAX vaccine. June 12, 2012 The red rash has still not improved and the burning sensation and some itching remains. I took a picture of the spots on my scalp this date.
Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Abdominal pain, Activities of daily living impaired, Chest X-ray, Chest discomfort, Chest pain
Clinical narrative: Information has been received from a physician concerning a 24 year old female patient with no drug reactions or allergies and with no pertinent medical history who on 09-JAN-2012 (reported also as "09-FEB-2012") was vaccinated with the first dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669794/1400AA) and on 17-APR-2012, was vaccinated with the second dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669795/1516AA). Concomitant therapy included hormonal contraceptives (unspecified). Subsequently, on an unknown date after the first dose the patient experienced pelvic pain which resolved before the second vaccination. After second vaccination, approximately in April 2012 the patient experienced left pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue. The patient had visited the Emergency Room and an Immediate Care Clinic. It was reported that the patient was unable to work. Lab diagnostic studies included: pelvic ultrasound, electrocardiogram, chest x-ray, echocardiogram, Magnetic resonance imaging (MRI) and Holter monitor (results not provided). There was no treatment given for AE. At the time of the report the patient's outcome was not recovered. The pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue were considered to be disabling since the patient was unable to work. Additional information has been requested.
Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Dyspnoea, Echocardiogram, Electrocardiogram, Electrocardiogram ambulatory, Fatigue
Clinical narrative: Information has been received from a physician concerning a 24 year old female patient with no drug reactions or allergies and with no pertinent medical history who on 09-JAN-2012 (reported also as "09-FEB-2012") was vaccinated with the first dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669794/1400AA) and on 17-APR-2012, was vaccinated with the second dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669795/1516AA). Concomitant therapy included hormonal contraceptives (unspecified). Subsequently, on an unknown date after the first dose the patient experienced pelvic pain which resolved before the second vaccination. After second vaccination, approximately in April 2012 the patient experienced left pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue. The patient had visited the Emergency Room and an Immediate Care Clinic. It was reported that the patient was unable to work. Lab diagnostic studies included: pelvic ultrasound, electrocardiogram, chest x-ray, echocardiogram, Magnetic resonance imaging (MRI) and Holter monitor (results not provided). There was no treatment given for AE. At the time of the report the patient's outcome was not recovered. The pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue were considered to be disabling since the patient was unable to work. Additional information has been requested.
Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Hypoaesthesia, Nuclear magnetic resonance imaging, Palpitations, Paraesthesia, Pelvic pain
Clinical narrative: Information has been received from a physician concerning a 24 year old female patient with no drug reactions or allergies and with no pertinent medical history who on 09-JAN-2012 (reported also as "09-FEB-2012") was vaccinated with the first dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669794/1400AA) and on 17-APR-2012, was vaccinated with the second dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669795/1516AA). Concomitant therapy included hormonal contraceptives (unspecified). Subsequently, on an unknown date after the first dose the patient experienced pelvic pain which resolved before the second vaccination. After second vaccination, approximately in April 2012 the patient experienced left pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue. The patient had visited the Emergency Room and an Immediate Care Clinic. It was reported that the patient was unable to work. Lab diagnostic studies included: pelvic ultrasound, electrocardiogram, chest x-ray, echocardiogram, Magnetic resonance imaging (MRI) and Holter monitor (results not provided). There was no treatment given for AE. At the time of the report the patient's outcome was not recovered. The pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue were considered to be disabling since the patient was unable to work. Additional information has been requested.
Age: 24.0
Sex: F
Vaccine: HPV4
Symptoms: Ultrasound pelvis
Clinical narrative: Information has been received from a physician concerning a 24 year old female patient with no drug reactions or allergies and with no pertinent medical history who on 09-JAN-2012 (reported also as "09-FEB-2012") was vaccinated with the first dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669794/1400AA) and on 17-APR-2012, was vaccinated with the second dose of GARDASIL (dose and route not reported) in deltoid of left arm (lot number: 669795/1516AA). Concomitant therapy included hormonal contraceptives (unspecified). Subsequently, on an unknown date after the first dose the patient experienced pelvic pain which resolved before the second vaccination. After second vaccination, approximately in April 2012 the patient experienced left pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue. The patient had visited the Emergency Room and an Immediate Care Clinic. It was reported that the patient was unable to work. Lab diagnostic studies included: pelvic ultrasound, electrocardiogram, chest x-ray, echocardiogram, Magnetic resonance imaging (MRI) and Holter monitor (results not provided). There was no treatment given for AE. At the time of the report the patient's outcome was not recovered. The pelvic pain, racing heart, shortness of breath, chest pain and tightness, intermittent abdominal pain, numbness, tingling in her right leg and arm and left hand and constant fatigue were considered to be disabling since the patient was unable to work. Additional information has been requested.
Sex: U
Vaccine: ANTH, DT, HEP, HEPA, SMALL, VARCEL
Symptoms: Pericardial disease
Clinical narrative: This study case was received from the investigator on 04 June 2012. A subject received the following vaccinations on 10 February 2012: an injection of ACAM2000 (lot number not reported), varicella (manufacturer and lot number not reported), anthrax (manufacturer and lot number not reported), hepatitis A (manufacturer and lot number not reported), hepatitis B (manufacturer and lot number not reported) and DT absorbed (manufacturer and lot number not reported). The subject also received a dose of ACAM2000 (lot number not reported) on 23 February 2012. On 23 February 2012, the subject was diagnosed with unspecific disease of pericardium. Medical history was not reported. The outcome was not reported. Additional information will be requested from the investigator. There is no reporter causality assessment as this is a safety surveillance study. Documents held by sender: None.
Sex: U
Vaccine: ANTH, HEP, SMALL, TYP
Symptoms: Pericardial disease
Clinical narrative: This study case was received from the investigator on 04 June 2012. A subject received the following vaccinations on 15 February 2012: an injection of ACAM2000 (lot number not reported), TYPHIM Vi (lot number not reported), anthrax (manufacturer and lot number not reported) and hepatitis B (manufacturer and lot number not reported). On 26 February 2012, the subject was diagnosed with unspecified disease of pericardium. Medical history was not reported. The outcome was not reported. Additional information will be requested from the investigator. There is no reporter causality assessment as this is a safety surveillance study. Documents held by sender: None.
Sex: U
Vaccine: ANTH, SMALL, TYP
Symptoms: Pericardial disease
Clinical narrative: This study case was received from the investigator on 04 June 2012. A subject received the following vaccinations on 12 March 2012: an injection of ACAM2000 (lot number not reported), TYPHIM Vi (lot number not reported) and anthrax (manufacturer not reported). On 22 March 2012, the subject was diagnosed with unspecified disease of pericardium. Medical history was not reported. The outcome was not reported. Additional information will be requested from the investigator. There is no reported causality assessment as this is a safety surveillance study. Documents held by sender: None.
Sex: U
Vaccine: SMALL
Symptoms: Pericardial disease
Clinical narrative: This study case was received from the investigator in a trial on 04 June 2012. A subject (age, date of birth and gender not reported) received the following vaccinations: On 01 December 2011 an injection of ACAM2000 (lot number not reported), on 29 November 2011 an injection of anthrax (manufacturer and lot number not reported) and on 30 November 2011 an injection of rabies (manufacturer and lot number not reported). On 19 December 2011, the subject was diagnosed with unspecified disease of pericardium. Medical history was not reported. The outcome was not reported. Additional information will be requested from the investigator. Note: There is no reporter causality assessment as this is a safety surveillance (data mining, non-interventional) study. Documents held by sender: None.
Sex: U
Vaccine: ANTH, HEPA, SMALL
Symptoms: Myocarditis
Clinical narrative: This study case was received from the investigator on 04 June 2012. A subject received the following vaccinations: On 13 February 2012: an injection of ACAM2000 (lot number not reported) and on 10 February 2012 an injection of anthrax (manufacturer and lot number not reported) and hepatitis A (manufacturer and lot number not reported). On 24 February 2012, the subject was diagnosed with non-specific myocarditis and on 27 February 2012, the subject was diagnosed with other and unspecified acute myocarditis. Medical history was not reported. The outcome was not reported. Additional information will be requested from the investigator. There is no reporter causality assessment as this is a safety surveillance study. Documents held by sender: None.
Age: 65.0
Sex: F
Vaccine: PPV
Symptoms: Arthralgia, Injection site swelling, Injection site urticaria, Malaise, Myalgia
Clinical narrative: Within 24 hrs after imm pt had shakes, felt "sick", swelling/hives upper deltoid at & proximal to inj. site, had progressively increasing joint & muscle pain. Pt has been alternating acetaminophen/ibuprofen - (see chart note for tx). MOTRIN 400 mg tid, ice off/on for 2 days then heat tid, BENADRYL 25 mg tid for 4 days call if not better then. Rest. VAERS form.
Age: 65.0
Sex: F
Vaccine: PPV
Symptoms: Tremor
Clinical narrative: Within 24 hrs after imm pt had shakes, felt "sick", swelling/hives upper deltoid at & proximal to inj. site, had progressively increasing joint & muscle pain. Pt has been alternating acetaminophen/ibuprofen - (see chart note for tx). MOTRIN 400 mg tid, ice off/on for 2 days then heat tid, BENADRYL 25 mg tid for 4 days call if not better then. Rest. VAERS form.
Age: 1.5
Sex: F
Vaccine: DTAPIPVHIB, HEPA
Symptoms: Full blood count normal, Influenza virus test negative, Lethargy, Pyrexia
Clinical narrative: Fever 103, lethargic at 1130 AM on 6-11-12 vaccines given at 0930 on 6-11-12 fever from 6-11-12 thru 6-13-12.
Age: 10.0
Sex: F
Vaccine: HPV4, MNQ, TDAP, HPV4, MNQ, TDAP
Symptoms: Neck pain
Clinical narrative: Left sided neck pain, started at midnight on 6/13/12. Vaccines given afternoon of 6/12/12.
Age: 0.53
Sex: F
Vaccine: DTAPIPVHIB, HEP, PNC13, RV5
Symptoms: Crying, Skin warm
Clinical narrative: Baby cried thru night after vac. Parents said felt warm to touch. Site without redness or without swelling.
Age: 16.0
Sex: M
Vaccine: HEPA, MNQ
Symptoms: Abdominal discomfort, Body temperature increased, Chills, Headache, Influenza
Clinical narrative: 06/07/12 Mother of client reports client woke up "not feeling so well," went to school & returned home early with a "wicked case of the flu," symptoms included chills, temp 101 degrees F, severe aches, upset stomach, headache. Mom called PCP nurse who encouraged Ibuprofen. Mom went to pharmacy & pharmacy-D thought it was a severe reaction to Hep A due to combo with MENACTRA. Mom gave Ibuprofen Q 4 hours 06/08/12 Mom reports child woke up a 8:00am & ate & seemed fine," did not report symptoms. Encouraged cont. supportive care. 06/13/12 client completely recovered.
Age: 16.0
Sex: M
Vaccine: HEPA, MNQ
Symptoms: Malaise, Pain
Clinical narrative: 06/07/12 Mother of client reports client woke up "not feeling so well," went to school & returned home early with a "wicked case of the flu," symptoms included chills, temp 101 degrees F, severe aches, upset stomach, headache. Mom called PCP nurse who encouraged Ibuprofen. Mom went to pharmacy & pharmacy-D thought it was a severe reaction to Hep A due to combo with MENACTRA. Mom gave Ibuprofen Q 4 hours 06/08/12 Mom reports child woke up a 8:00am & ate & seemed fine," did not report symptoms. Encouraged cont. supportive care. 06/13/12 client completely recovered.
Age: 65.0
Sex: F
Vaccine: VARZOS
Symptoms: Eye pain, Eye swelling, Herpes zoster, Herpes zoster ophthalmic, Scab
Clinical narrative: Patient received ZOSTAVAX in 2008. Had shingles outbreak 2012. Eye swelled & was painful May 28th, 2012 shingles appeared 6-3-2012 5 on eyelid 1, on side of forehead, lesions crusted now.
Age: 65.0
Sex: F
Vaccine: VARZOS
Symptoms: Vaccination failure
Clinical narrative: Patient received ZOSTAVAX in 2008. Had shingles outbreak 2012. Eye swelled & was painful May 28th, 2012 shingles appeared 6-3-2012 5 on eyelid 1, on side of forehead, lesions crusted now.
Age: 18.0
Sex: F
Vaccine: HPV4, MNQ, VARCEL, HPV4, MNQ, VARCEL
Symptoms: Injection site erythema, Injection site pain, Injection site pruritus, Injection site swelling, Injection site warmth
Clinical narrative: Vaccine administered 6/12/12, on 6/13 patient had swelling, hot area, itching, redness and tenderness around site.
Age: 45.0
Sex: F
Vaccine: FLU3
Symptoms: Blood test, Urticaria
Clinical narrative: I received the flu shot on October 29, 2011 and began having hives on November 2, 2011. I have had hives everyday since November 2, 2011.
Age: 58.0
Sex: F
Vaccine: FLU3
Symptoms: Biopsy, Blindness, Blood test
Clinical narrative: Partial loss of vision OS.
Age: 65.0
Sex: F
Vaccine: VARZOS
Symptoms: Neuralgia, Skin lesion
Clinical narrative: None. One lesion on left elbow. Nerve pain in left arm.
Age: 12.0
Sex: F
Vaccine: HPV2
Symptoms: Urticaria
Clinical narrative: Received CERVARIX immunization #1 on 6-12-12. Later in day broke out in hives over entire body. BENADRYL given by parent.
Age: 18.0
Sex: F
Vaccine: HPV4, HPV4
Symptoms: Extremity contracture, Fall, Loss of consciousness, Staring
Clinical narrative: Pt. received HPV #3 and PPD. Stood up to walk to door and headed to wall, then passed out - falling to floor. Was out 5-10 seconds only. Lied on floor for 5-10 min. - felt better - sat in chair to check vitals. Pts. head fell back, arms contracted and eyes glazed over (? seizure), lasted 10-15 sec. - pt. lied down and taken to ER via amb. - was alert and awake.
Age: 18.0
Sex: F
Vaccine: HPV4, HPV4
Symptoms: Fall, Loss of consciousness, Muscle contractions involuntary, Posture abnormal, Staring
Clinical narrative: Pt. received HPV #3 and PPD. Stood up to walk to door and headed to wall, then passed out - falling to floor. Was out 5-10 seconds only. Lied on floor for 5-10 min. - felt better - sat in chair to check vitals. Pts. head fell back, arms contracted and eyes glazed over (? seizure), lasted 10-15 sec. - pt. lied down and taken to ER via amb. - was alert and awake.
Age: 10.0
Sex: M
Vaccine: TDAP, VARCEL
Symptoms: Injection site erythema, Injection site pruritus, Injection site swelling
Clinical narrative: Site of injection swollen - with itching and redness.
Age: 0.85
Sex: F
Vaccine: DTAPIPVHIB, PNC
Symptoms: Eye disorder, Salivary hypersecretion, Tremor
Clinical narrative: Arrived at hospital on 6/13/12 at 1:25 am - presents with episode generalized shaking, eyes opened, increased saliva, no vomiting during event. Lasting x 10 mins. Took 10-15 mins for child to be back to normal status. No fever. Denies new rash, diarrhea, vomiting, URI, behavior change.
Age: 36.0
Sex: F
Vaccine: PPV
Symptoms: Injection site erythema, Injection site pain, Injection site swelling
Clinical narrative: Extreme pain with egg-sized swelling on the 12th.  On the 13th, the pain remains, and the swelling has expanded from injection site to just above elbow on right arm. The swollen area is now red.
Age: 29.0
Sex: F
Vaccine: TDAP
Symptoms: Eyelid oedema, Limb discomfort, Muscle tightness, Neck pain, Pain in extremity
Clinical narrative: Shortly after vaccine was administered, while driving home, pt experienced left neck and arm "tightness" that radiated to jaw. 1/2 Benadryl tablet taken at 4:00PM for same symptoms. Another 1/2 tablet of Benadryl + 200mg of Ibuprofen taken at 8:00PM for pain and tightness of left arm and neck. At 5:00AM on 6/13/2012, pt awoke and stated she felt her throat,ears and neck began to "feel itchy". Pt took 1 Benadryl tablet and 200mg Ibuprofen for itchiness and for slight wheezing. At 9:00AM, pt phoned HD to report this reaction. States "I feel pretty good right now - my eyes are a little puffy, but I don't feel itchy or stiff now". Inst. to seek medical help immediately if breathing is compromised.
Age: 29.0
Sex: F
Vaccine: TDAP
Symptoms: Pruritus, Throat irritation, Wheezing
Clinical narrative: Shortly after vaccine was administered, while driving home, pt experienced left neck and arm "tightness" that radiated to jaw. 1/2 Benadryl tablet taken at 4:00PM for same symptoms. Another 1/2 tablet of Benadryl + 200mg of Ibuprofen taken at 8:00PM for pain and tightness of left arm and neck. At 5:00AM on 6/13/2012, pt awoke and stated she felt her throat,ears and neck began to "feel itchy". Pt took 1 Benadryl tablet and 200mg Ibuprofen for itchiness and for slight wheezing. At 9:00AM, pt phoned HD to report this reaction. States "I feel pretty good right now - my eyes are a little puffy, but I don't feel itchy or stiff now". Inst. to seek medical help immediately if breathing is compromised.
Age: 46.0
Sex: M
Vaccine: RAB
Symptoms: Dizziness, Lethargy, Nausea, Pain
Clinical narrative: Two hours after receiving the vaccination, the client experienced dizziness and "light headed" with some nausea.  Client jogged the next day and actually experienced nausea and vomiting and was checked by emergency medical services who reported normal blood pressure and pulse.  Two days later, cleint expereincing aching and lethargy.  Clients takes no medications, but has been taking Tylenol for headaches.
Age: 65.0
Sex: M
Vaccine: HEP
Symptoms: Body temperature, Feeling hot, Heart rate increased, Urticaria
Clinical narrative: Hives, elevated heart rate, horness, slight temp.
Age: 35.0
Sex: F
Vaccine: DTAP, HEP, HEPA, MMR
Symptoms: Arthralgia, Biopsy skin abnormal, Blister, Blood test, Eosinophilic cellulitis
Clinical narrative: Itching rash with large hives and blisters, muscle and joint pain, fatigue.
Age: 35.0
Sex: F
Vaccine: DTAP, HEP, HEPA, MMR
Symptoms: Fatigue, Myalgia, Rash pruritic, Urticaria
Clinical narrative: Itching rash with large hives and blisters, muscle and joint pain, fatigue.
Age: 53.0
Sex: M
Vaccine: HEP
Symptoms: Abdominal pain, Muscle spasms, Rash erythematous
Clinical narrative: 3-4 dozen non-raised "pink spots" on torso "under belt area" no itching, pain or drainage; muscle cramping of abdominal muscles and legs predominately on the left side.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Arthralgia, Hypoaesthesia, Injection site pain, Injection site swelling, Lymph node pain
Clinical narrative: Severe lymph node pain and swelling, severe pain and swelling injection site, finger tip numbness and tingling, and joint pain and stiffness in arm where injection given.
Age: 37.0
Sex: F
Vaccine: TDAP
Symptoms: Lymphadenopathy, Musculoskeletal stiffness, Paraesthesia
Clinical narrative: Severe lymph node pain and swelling, severe pain and swelling injection site, finger tip numbness and tingling, and joint pain and stiffness in arm where injection given.
Age: 59.0
Sex: M
Vaccine: YF
Symptoms: Expired drug administered, No adverse event
Clinical narrative: Expired vaccine was administered to patient. He did not report any illness or reaction to the vaccination.
Age: 59.0
Sex: M
Vaccine: VARZOS
Symptoms: Injection site warmth, Pruritus
Clinical narrative: Localized itching and warmth at injection site developed in the first 10 minutes following injection. Patient was given diphenhydramine 100mg PO x 1 and monitoring continued. MD contacted, advised cold compresses, APAP/IBU prn. By 11:30, itching subsided, still warm. MD okay to send home, pt agreeable, will monitor and call MD if sx worsen.
Age: 58.0
Sex: F
Vaccine: PPV
Symptoms: Musculoskeletal pain
Clinical narrative: Shoulder began to hurt.  Pain increasingly worse after 3 weeks.  Still no relief.
Age: 4.0
Sex: M
Vaccine: DTAP, IPV, MMR, PNC13, VARCEL
Symptoms: Urticaria
Clinical narrative: Single urticarial lesion 2 cm distal to the injection site.
Age: 65.0
Sex: M
Vaccine: VARZOS
Symptoms: Cough, Dysphonia, Nasopharyngitis, Oropharyngeal pain, Pyrexia
Clinical narrative: Started with sore throat, developed into full fledge cold with mild fever and stuffed sinuses and sore throat.  Lasted 4-5 days, though cough is continuing symptom as chest clears.  Then four days later, seemed to come back as sneezing, more seriously stuffed sinuses, runny nose and hoarseness.  Still going four days later.
Age: 65.0
Sex: M
Vaccine: VARZOS
Symptoms: Rhinorrhoea, Sinus congestion, Sneezing
Clinical narrative: Started with sore throat, developed into full fledge cold with mild fever and stuffed sinuses and sore throat.  Lasted 4-5 days, though cough is continuing symptom as chest clears.  Then four days later, seemed to come back as sneezing, more seriously stuffed sinuses, runny nose and hoarseness.  Still going four days later.
Age: 21.0
Sex: M
Vaccine: FLU(H1N1), FLUN3
Symptoms: Activities of daily living impaired, Bedridden, Disturbance in attention, Epstein-Barr virus antibody positive, Epstein-Barr virus infection
Clinical narrative: Health declined precipitously roughly 3-4 months after receiving the vaccine (h1n1 spray). -extreme fatigue -reduced mental abilities (concentration, brain fog, word recall) -lowered white blood cell count -recurrence of acute EBV infection (positive IgM) and other infections -dropped out of school, unable to work -currently bed bound
Age: 21.0
Sex: M
Vaccine: FLU(H1N1), FLUN3
Symptoms: Fatigue, General physical health deterioration, Mental disability, Nervous system disorder, Speech disorder
Clinical narrative: Health declined precipitously roughly 3-4 months after receiving the vaccine (h1n1 spray). -extreme fatigue -reduced mental abilities (concentration, brain fog, word recall) -lowered white blood cell count -recurrence of acute EBV infection (positive IgM) and other infections -dropped out of school, unable to work -currently bed bound
Age: 21.0
Sex: M
Vaccine: FLU(H1N1), FLUN3
Symptoms: White blood cell count decreased
Clinical narrative: Health declined precipitously roughly 3-4 months after receiving the vaccine (h1n1 spray). -extreme fatigue -reduced mental abilities (concentration, brain fog, word recall) -lowered white blood cell count -recurrence of acute EBV infection (positive IgM) and other infections -dropped out of school, unable to work -currently bed bound
Age: 0.19
Sex: F
Vaccine: DTAPHEPBIP, HIBV, PNC13, RV1
Symptoms: Death
Clinical narrative: Infant died.
Age: 68.0
Sex: F
Vaccine: VARZOS
Symptoms: Injection site erythema, Injection site induration, Injection site swelling, Injection site warmth
Clinical narrative: 3X1.5inch RED, RAISED, WARM, HARD AREA AT SITE OF INJECTION. ADVISED ICE AND ANTIHISTAMINES.
Age: 11.0
Sex: F
Vaccine: HPV4
Symptoms: Alanine aminotransferase increased, Angioedema, Aspartate aminotransferase increased, Bilirubin urine, Blood urine present
Clinical narrative: Puffy eyes developed overnight the night after vaccine administered.  Benadryl no help. Continued to wake with puffy eyes for a few mornings. 2/27/12 seen by MD for a fine erythematous maculopapular rash which developed on extremities and trunk.  Rash faded but thereafter would recur with exertion.  Eye swelling became more prominent even into the evening.  Seen by MD again 3/2/12 for periorbital edema.  Urine dip was neg except for trace blood.  Suspected post-streptococcal glomerulonephritis.  Throat culture was positive for group A strep and patient was treated with Amoxicillin starting on 3/4/12.  Other bloodwork was negative at the time except for AST 62 and ALT 77.  Eye swelling persisited and was referred to allergist.  Her angioedema was thought to be post-viral.  A urine dip showed trace blood, trace protein and 2+ bilirubin.  Treated with 9 day steroid taper, after which angioedema never recurred.  On 3/7/12, AST 216, ALT 260.  By 3/16/12, AST 24, ALT 66. No further blood in urine.  As of 5/8/12, rash continues to recurr with exercise, though less frequently now.
Age: 11.0
Sex: F
Vaccine: HPV4
Symptoms: Culture throat positive, Eye swelling, Eyelid oedema, Periorbital oedema, Post streptococcal glomerulonephritis
Clinical narrative: Puffy eyes developed overnight the night after vaccine administered.  Benadryl no help. Continued to wake with puffy eyes for a few mornings. 2/27/12 seen by MD for a fine erythematous maculopapular rash which developed on extremities and trunk.  Rash faded but thereafter would recur with exertion.  Eye swelling became more prominent even into the evening.  Seen by MD again 3/2/12 for periorbital edema.  Urine dip was neg except for trace blood.  Suspected post-streptococcal glomerulonephritis.  Throat culture was positive for group A strep and patient was treated with Amoxicillin starting on 3/4/12.  Other bloodwork was negative at the time except for AST 62 and ALT 77.  Eye swelling persisited and was referred to allergist.  Her angioedema was thought to be post-viral.  A urine dip showed trace blood, trace protein and 2+ bilirubin.  Treated with 9 day steroid taper, after which angioedema never recurred.  On 3/7/12, AST 216, ALT 260.  By 3/16/12, AST 24, ALT 66. No further blood in urine.  As of 5/8/12, rash continues to recurr with exercise, though less frequently now.
Age: 11.0
Sex: F
Vaccine: HPV4
Symptoms: Protein urine present, Rash, Rash erythematous, Rash maculo-papular, Streptococcus test positive
Clinical narrative: Puffy eyes developed overnight the night after vaccine administered.  Benadryl no help. Continued to wake with puffy eyes for a few mornings. 2/27/12 seen by MD for a fine erythematous maculopapular rash which developed on extremities and trunk.  Rash faded but thereafter would recur with exertion.  Eye swelling became more prominent even into the evening.  Seen by MD again 3/2/12 for periorbital edema.  Urine dip was neg except for trace blood.  Suspected post-streptococcal glomerulonephritis.  Throat culture was positive for group A strep and patient was treated with Amoxicillin starting on 3/4/12.  Other bloodwork was negative at the time except for AST 62 and ALT 77.  Eye swelling persisited and was referred to allergist.  Her angioedema was thought to be post-viral.  A urine dip showed trace blood, trace protein and 2+ bilirubin.  Treated with 9 day steroid taper, after which angioedema never recurred.  On 3/7/12, AST 216, ALT 260.  By 3/16/12, AST 24, ALT 66. No further blood in urine.  As of 5/8/12, rash continues to recurr with exercise, though less frequently now.