Age: 53.0
Sex: F
Vaccine: COVID19
Symptoms: Erythema, Exercise tolerance decreased, Fatigue, Feeling abnormal, Gait disturbance
Clinical narrative: Heart palpitations/fluttering; Severe 24/7 nerve pain in my hands and feet (pins and needles, cramping, tingling, burning, itching, etc.); Muscle cramps; Muscle twitching throughout whole body; Muscle stiffness; Difficulty walking; Heat/cold/exercise intolerance; Heat/cold/exercise intolerance; Fatigue; Nausea; Off balance; Insomnia; Brain fog; Blurred vision; Increased dry eyes; Heart palpitations/fluttering; Tachycardia; Extreme highs (Apple Watch verified) showed seated heart rate in excess of 100 with seated heart rate highs to 165; Purple/bruised looking toes; Purple/bruised looking toes; Inflammation/swelling/redness in hands and feet; Inflammation/swelling/redness in hands and feet; Inflammation/swelling/redness in hands and feet; Inflammation/swelling/redness in hands and feet; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 53 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 02Apr2021 (Lot number: EW0150) at the age of 53 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Breast cancer - DCIS Stage 0 (recovered)" (unspecified if ongoing), notes: Breast cancer - DCIS Stage 0 (recovered); "Positive ANA" (unspecified if ongoing), notes: Positive ANA - not specific; "Known allergies: Bees" (unspecified if ongoing); "Known allergies: Topical iodine" (unspecified if ongoing); "Known allergies: Adhesive tape" (unspecified if ongoing), notes: Adhesive tape causes rash; "Adhesive tape causes rash" (unspecified if ongoing). Prior to vaccination, patient was not diagnosed with COVID-19. Since the vaccination, the patient has not been tested for COVID-19. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. There were no concomitant medications. The patient did not receive any other medications within 2 weeks of vaccination. The following information was reported: CARDIAC FLUTTER (disability, medically significant), PALPITATIONS (disability) all with onset 02Apr2021 17:00, outcome "not recovered" and all described as "Heart palpitations/fluttering"; NEURALGIA (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Severe 24/7 nerve pain in my hands and feet (pins and needles, cramping, tingling, burning, itching, etc.)"; MUSCLE SPASMS (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Muscle cramps"; MUSCLE TWITCHING (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Muscle twitching throughout whole body"; MUSCULOSKELETAL STIFFNESS (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Muscle stiffness"; GAIT DISTURBANCE (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Difficulty walking"; TEMPERATURE INTOLERANCE (disability), EXERCISE TOLERANCE DECREASED (disability) all with onset 02Apr2021 17:00, outcome "not recovered" and all described as "Heat/cold/exercise intolerance"; FATIGUE (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Fatigue"; NAUSEA (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Nausea"; BALANCE DISORDER (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Off balance"; INSOMNIA (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Insomnia"; FEELING ABNORMAL (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Brain fog"; VISION BLURRED (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Blurred vision"; DRY EYE (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Increased dry eyes"; TACHYCARDIA (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Tachycardia"; HEART RATE INCREASED (disability) with onset 02Apr2021 17:00, outcome "not recovered", described as "Extreme highs (Apple Watch verified) showed seated heart rate in excess of 100 with seated heart rate highs to 165"; BLUE TOE SYNDROME (disability), CONTUSION (disability) all with onset 02Apr2021 17:00, outcome "not recovered" and all described as "Purple/bruised looking toes"; INFLAMMATION (disability), PERIPHERAL SWELLING (disability), PERIPHERAL SWELLING (disability), ERYTHEMA (disability) all with onset 02Apr2021 17:00, outcome "not recovered" and all described as "Inflammation/swelling/redness in hands and feet". The events "severe 24/7 nerve pain in my hands and feet (pins and needles, cramping, tingling, burning, itching, etc.)", "muscle cramps", "muscle twitching throughout whole body", "muscle stiffness", "difficulty walking", "heat/cold/exercise intolerance", "heat/cold/exercise intolerance", "fatigue", "nausea", "off balance", "insomnia", "brain fog", "blurred vision", "increased dry eyes", "heart palpitations/fluttering", "tachycardia", "extreme highs (apple watch verified) showed seated heart rate in excess of 100 with seated heart rate highs to 165", "purple/bruised looking toes", "purple/bruised looking toes", "inflammation/swelling/redness in hands and feet", "inflammation/swelling/redness in hands and feet", "inflammation/swelling/redness in hands and feet" and "inflammation/swelling/redness in hands and feet" were evaluated at the physician office visit. Severe 24/7 nerve pain in my hands and feet (pins and needles, cramping, tingling, burning, itching, etc.) Muscle cramps, muscle twitching throughout whole body, muscle stiffness and difficulty walking. Heat/cold/exercise intolerance, fatigue, nausea, off balance, insomnia, and brain fog. Blurred vision and increased dry eyes. Heart palpitations/fluttering, tachycardia, extreme highs (Apple Watch verified) showed seated heart rate in excess of 100 with seated heart rate highs to 165 post vaccine Purple/bruised looking toes; inflammation/swelling/redness in hands and feet Followed up with Primary Care, Rheumatologist and NIH after reaction. Patient currently under the care of primary care, neurologist, cardiologist, hematologist, rheumatologist.  Still in the process of confirming small fiber neuropathy, MCAS, dysautonomia, and other autoimmune disorders resulting from vaccine reaction. She was on no medications prior to the vaccine. She is now on multiple meds to control symptoms. Treatment received for the adverse event: 7 prescriptions, 2 supplements, diagnostic tests. The patient underwent the following laboratory tests and procedures: heart rate: (02Apr2021) 100, notes: seated heart rate in excess; (02Apr2021) 165, notes: seated heart rate highs. Therapeutic measures were taken as a result of cardiac flutter, neuralgia, muscle spasms, muscle twitching, musculoskeletal stiffness, gait disturbance, temperature intolerance, exercise tolerance decreased, fatigue, nausea, balance disorder, insomnia, feeling abnormal, vision blurred, dry eye, palpitations, tachycardia, heart rate increased, blue toe syndrome, contusion, inflammation, peripheral swelling, peripheral swelling, erythema.