Sex: F
Vaccine: COVID19
Symptoms: Myelitis transverse
Clinical narrative: TRANSVERSE MYELITIS; This spontaneous report received from a patient who was a healthcare professional concerned a 65 year old female.  Additional information was also received via Company physician on 07-JAN-2022 via telephone communication log, and processed in this case version.   The patient's height and weight were not reported.  No past medical or family history of neurological disease. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 1802072) dose was not reported, administered in the left arm on 17-MAR-2021 for prophylactic vaccination. The patient was on no concomitant medications.   On 21-MAR-2021 (also reported as 22-MAR-2021), symptoms started with severe pain and severe tightness (muscles wouldn't move) in exactly both sides of outer thighs, upper arms, shoulders and neck. Stated lower arms and lower legs were not affected at first. As per consumer, she thought she had just overdone it (working in the emergency room). On an unspecified date she couldn't get out of the bed and "couldn't move anything".  Symptoms were bilateral.  The patient had no bowel or bladder problems.  The patient had no neurological problems related to the spinal cord, and no neurological problems coming from one specific part of the spinal cord.   In MAY-2021 she went to the doctor and was diagnosed with transverse myelitis. No MRI or CT scans were done, and "any studies or imaging with evidence for tumors if performed" was indicated as no.  She was given prednisone and Neurontin, which eased up symptoms and she was able to deal with it. The patient stated at first she was getting "shots" which worked for 3 weeks and then it would come back and needed to get another "shot". One day, after 3 weeks from last shot, she wasn't able to get out of bed and ended up in the emergency room where she got intravenous steroids. Since then, she was prescribed daily oral steroids 5-20 mg. The patient stated when symptoms flare up it is in her wrist and hands.   As of 07-JAN-2022, the symptoms have improved, but she still has occasional pain bilaterally in her hands.  She was currently taking prednisone 5 mg daily, as well as Neurontin 400 mg daily.   The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient was recovering ("symptoms have improved") from transverse myelitis. This report was serious (Other Medically Important Condition).; Sender's Comments: This spontaneous report received from a patient who was a healthcare professional concerned a 65-year-old female who experienced transverse myelitis 4 days after vaccine. The patient has no past medical conditions including neurological disease and is not using any concomitant medications. Four days after vaccine the patient started experiencing severe muscle tightness leading to not being able to get out of bed on an unspecified day. There were no bowel or bladder symptoms and neurological problems. Approximately two months after the vaccine the patient was diagnosed with transverse myelitis. No imaging was done and no diagnostic information was provided. She was treated with Neurontin and prednisone and her symptoms decreased. She was started on steroids after not being able to get out of bed after 3 weeks of treatment and was prescribed oral prednisone. She experienced symptoms in hands and wrists during flares. Ten months after the vaccine the patient was improving but she experiences occasional pain in hands and wrists. The outcome was reported as recovering. Information is limited in this case. However, a relationship with Janssen Covid-19 vaccine cannot be ruled out and thus the relationship is considered indeterminate.