Age: 45.0
Sex: F
Vaccine: COVID19
Symptoms: Parosmia, Polymerase chain reaction, Product use issue, Taste disorder
Clinical narrative: smell all the same (terrible) and taste weird; smell all the same (terrible) and taste weird; BNT162B2  dose 1 and 2 received on 27Jan2021; This is a spontaneous report from a contactable other healthcare professional (patient). A 45-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, lot number:  EL9261), single dose, dose 1 intramuscular, administered in the left arm on 27Jan2021 at 08:15 and BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, lot number: EN6198), single dose, dose 2 via an unspecified route of administration, administered in the left arm on 27Jan2021 (at the age of 45-years-old) for COVID-19 immunization. The patient's medical history was not reported. The patient was not pregnant at the time of vaccination. Concomitant medications included bupropion hydrochloride (WELLBUTRIN) 150 mg taken for an unspecified indication, start and stop date were not reported; naltrexone 4mg taken for an unspecified indication, start and stop date were not reported; bifidobacterium bifidum, bifidobacterium lactis, bifidobacterium longum, lactobacillus acidophilus, lactobacillus rhamnosus (PROBIOTIC [BIFIDOBACTERIUM BIFIDUM;BIFIDOBACTERIUM LACTIS;BIFIDOBACTERIUM LONGUM;LACTOBACILLUS ACIDOPHILUS;LACTOBACILLUS RHAMNOSUS]) taken for an unspecified indication, start and stop date were not reported and calcium levomefolate (DEPLIN) taken for an unspecified indication, start and stop date were not reported. The patient did not receive  any other vaccine within 4 weeks prior to the vaccine. The patient previously took sulfa [sulfadiazine] and experienced drug hypersensitivity. On 19Mar2021 at  6:45 AM, I woke up to my husband bringing me coffee to bed. (My favorite thing). It smelled like our cat's super stinky wet cat food! I told him something was wrong with the coffee but he insisted it was fine. Since that day, cat food, coffee, steaks, dog poop, and several other things smell all the same (terrible) and taste weird. My toothpaste tastes like urine in a cat litter box (I'm using cat references because it's not the closest thing I can come up with to describe the smell/taste/sensation. The patient underwent lab tests and procedures which included polymerase chain reaction: negative on 24Feb2021 Nasal Swab. Therapeutic measures were taken as a result of smell all the same (terrible) and taste weird and included antibiotics and steroids hoping it was sinus related.The clinical outcome of smell all the same (terrible) and taste weird was not recovered. It was also reported that since the vaccination, the patient was tested for COVID-19 and was negative.; Sender's Comments: Based on the information currently available, a possible contributory role of the suspect drug to the reported events "smell all the same (terrible) and taste weird" cannot be completely excluded based on temporal association.   The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identifies as part of this review, as well as any appropriate action in response, will be promptly notifies to  Committees and Investigators, as appropriate.