chrisvoncsefalvay/vaers-narrative-generation huggingface dataset:
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Bacterial infection, Skin ulcer
Clinical narrative: On May 17, 1999 the patient experienced approximately 20 lesions and a secondary strep throat infection.
Age: 25.0
Sex: F
Vaccine: VARCEL
Symptoms: Fatigue, Nausea, Skin ulcer
Clinical narrative: The pt experienced 12 lesions, was feeling nauseous and tired. No further information is available.
Age: 1.2
Sex: F
Vaccine: VARCEL
Symptoms: Dermatitis bullous
Clinical narrative: On May 17th 1999 three weeks post vax, the pt developed mild chickenpox rash. There were about twenty lesions and some of the lesions were filled with fluid. It was noted that no treatment needed. The patients MD noted in follow-up that the patient's rash faded and drying of vesicles resolved by May 25th 1999.
Age: 2.0
Sex: M
Vaccine: VARCEL
Symptoms: Blister, Drug ineffective, Infection, Skin ulcer
Clinical narrative: The patient was exposed to his older brother who experienced wild type varicella. On approximately May 20, 1999 the patient developed a mild course of chickenpox. The MD noted that the lesions were smaller and fewer were fluid filled than the older brother's. The pt did not require treatment.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Urticaria
Clinical narrative: Nine days post vax the pt developed varicella like lesions. On 04/04/1998 the pt developed a few hive like lesions that crusted over.
Age: 2.0
Sex: M
Vaccine: VARCEL
Symptoms: Pyrexia, Rash, Skin ulcer
Clinical narrative: On May 17, 1999 the pt experienced a rash, fever x 7 days and more than 100 lesions with scarring. The pt sought unspecified medical treatment. Additionally it was noted that 7 other pt's experienced similar reactions.
Age: 29.0
Sex: F
Vaccine: VARCEL
Symptoms: Infection, Pyrexia
Clinical narrative: On May 14, 1999 the pt experienced varicella with fever. The pt was 34-36 weeks pregnant the time of onset.
Age: 5.0
Sex: F
Vaccine: VARCEL
Symptoms: Herpes zoster, Infection
Clinical narrative: Subsequently the pt developed shingles.
Age: 7.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 22, 1999 the pt was seen by a physician and confirmed to have chickenpox, with less than 100 lesions.
Sex: M
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Skin ulcer
Clinical narrative: On May 24, 1999 the pt experienced varicella like rash with approximately 12 lesions.
Age: 45.0
Sex: M
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Pyrexia
Clinical narrative: Subsequently the pt developed eight varicella type lesions with fever.
Age: 45.0
Sex: U
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Headache, Lymphadenopathy, Pyrexia
Clinical narrative: Subsequently the pt experienced a varicella like rash, fever, mild lymphadenopathy and headache.
Age: 11.0
Sex: M
Vaccine: VARCEL
Symptoms: Blister, Headache, Infection, Lymphadenopathy, Pruritus
Clinical narrative: On May 19, 1999 the pt developed chickenpox with about 10 vesicles, itching and a temp of 100F, The pt also experienced a headache and swollen glands for about a day. The pt's mother reported that he had been exposed to varicella prior to vax.
Age: 11.0
Sex: M
Vaccine: VARCEL
Symptoms: Pyrexia
Clinical narrative: On May 19, 1999 the pt developed chickenpox with about 10 vesicles, itching and a temp of 100F, The pt also experienced a headache and swollen glands for about a day. The pt's mother reported that he had been exposed to varicella prior to vax.
Sex: M
Vaccine: VARCEL
Symptoms: Skin ulcer
Clinical narrative: On May 22, 1999 the pt experienced approximately 10 lesions.
Sex: U
Vaccine: VARCEL
Symptoms: Infection
Clinical narrative: Subsequently pt experienced a varicella infection. Additionally it was noted that another pt experienced similar reaction.
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: Subsequently the pt experienced a lack of response.
Age: 26.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: Stated by reported that pt has been taking vaccine since 1996 and has not worked.
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Pyrexia
Clinical narrative: On May 20, 1999 the pt broke out in a case of full blown chickenpox with greater than 75 lesions and a fever.
Sex: F
Vaccine: VARCEL
Symptoms: Pyrexia
Clinical narrative: Within one week of vax, the pt experienced a fever.
Age: 1.5
Sex: M
Vaccine: MMR, OPV, VARCEL
Symptoms: Rash vesicular
Clinical narrative: On May 12, 1999 the patient presented to the physician with approximately 5-6 lesions which were described as grape clusters on an erythematous base. The pt was afebrile, it was indicated that the pt's mother and brother had similar episodes.
Age: 1.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: In January, 1999 the pt experienced chickenpox.
Age: 10.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 24, 1999 the pt experienced varicella with approximately 50 lesions on the chest, back, thigh and neck.
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On Jan. 22, 1999 the pt experienced a chickenpox breakthrough.
Age: 5.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On 07-Jan-1999 the pt experienced breakthrough chickenpox. Subsequently, the pt recovered.
Age: 8.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On 02/04/1999 the pt developed a breakthrough case of chickenpox. No further information is available.
Age: 3.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 24, 1999 the pt experienced breakthrough chickenpox.
Age: 18.0
Sex: F
Vaccine: HEP, VARCEL
Symptoms: Laboratory test abnormal, Upper respiratory tract infection
Clinical narrative: Subsequently, she was found to be pregnant. LMP was 03/15/1999. Expected delivery date is 12/20/1999. F/U was received which indicated the request for follow up was fowarded to obstetrician. F/U received from RN. During pregnancy the pt took a prenatal vitamin and iron supplement. Pt experienced an upper respiratory infection during the pregnancy. Preterm labor was experienced. On Jan. 17, 2000 at 42 weeks gestation the pt gave birth to a normal healthy male. Birth wgt was 7 lb 14 oz. Follow up provided no additional data. No further information is available.
Age: 2.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 23, 1999 the pt developed chickenpox breakthrough with approximately 75-100 generalized lesions. The pt was afebrile. The child was prosented to a physician with sx on May 26, 1999.
Age: 3.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 25, 1999 the patient developed chickenpox with approximately 10-12 lesions.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 24, 1999 the patient developed chickenpox with several lesions on his stomach, chest, ears, face and scalp, one in his mouth and approximately two on both arms. The patient was febrile. The reporter believed that there was no association between the pt's symptom and the vax.
Age: 3.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 25, 1999 the pt experienced chickenpox with 20 lesions.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 25, 1999 the pt experienced chickenpox with 14 lesions.
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: Pt was vaccinated with two doses of varicella live three months apart. Subsequent lab evaluation revealed a lack of response.
Age: 23.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Unevaluable event
Clinical narrative: Pt was recently exposed to varicella.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 27th 1999 the pt experienced chicken pox, very mild with 12-15 lesions so far. The pt was treated with diphenhydramine hcl and colloidal oatmeal.
Age: 2.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 17, 1999 the pt experienced chicken pox with an unknown number of lesions, mild severity without complications. The pt was treated with acyclovir.
Age: 2.6
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: Pt was 06/20/1997 and Aug 21, 1997 was vaccinated with the first and second doses, respectively, of varicella. Concomitant vax on Jun 6, 1997 and July 8,1997 included the first and second doses, respectively of heb B vax. Other concomitant medications included loratadine and ethinyl norethindrone acetate.  On 5/20/99, the pt had an antibody test that revealed a failure to seroconvert.
Age: 1.0
Sex: U
Vaccine: VARCEL
Symptoms: Skin ulcer
Clinical narrative: Pt experienced three leasions.
Age: 1.3
Sex: M
Vaccine: OPV, VARCEL, OPV, VARCEL
Symptoms: Oedema peripheral, Skin nodule, Vasodilatation
Clinical narrative: after recV vax pt devel very large red hot swollen lt leg, hard lump
Age: 12.0
Sex: F
Vaccine: HEP, VARCEL, HEP, VARCEL
Symptoms: Dermatitis bullous
Clinical narrative: after recv vax pt 4 days later devel rash compatible to varicella, temp 102
Age: 3.0
Sex: F
Vaccine: VARCEL, VARCEL
Symptoms: Unevaluable event
Clinical narrative: MD visit 6/7/99 acyclovir 100/5 1/2 tsp tid x 5d;atarax 10/5 3/4 tsp po q 6hr PRN;
Age: 3.0
Sex: F
Vaccine: VARCEL, VARCEL
Symptoms: Unevaluable event
Clinical narrative: MD visit 6/7/99 acylovir 200/5 1/2 tsp x 5 days;atarax 10/5 3/4 tsp po q 6hr PRN;
Age: 29.0
Sex: F
Vaccine: VARCEL, VARCEL
Symptoms: Rash maculo-papular
Clinical narrative: Information has been received from a physician concerning a 29 year old female patient who in February 1999 was vaccinated with one dose of varicella. Concomitant therapy included birth control pills. On 23-FEB-1999 the patient experienced approximately 25 to 30 erythematous papules throughout her body. She had no fever and the papules did not vesiculate or crust, and there was no necrosis. The patient sought unspecified medical attention. PCR analysis results are pending. A skin biopsy was also performed with results pending. No further information is available.
Age: 19.0
Sex: M
Vaccine: VARCEL, VARCEL
Symptoms: Dermatitis bullous, Rash, Vomiting
Clinical narrative: 1 days n/v;flu sx, rash;seen 6/8/99 six vesiculopapular lesions chest & scalp;rx zovirax;
Age: 22.0
Sex: F
Vaccine: VARCEL, VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: a cousin of pt visited pt home 3wk prior to 3/8/99 cousin devel chickenpox 2wk later;pt & parents devel chickenpox 3wk p/the cousin's visit;pt had about 20 to 25 lesions on trunk parents had full blown chickenpox;pr recovered in 3 to 4 days
Age: 25.0
Sex: M
Vaccine: VARCEL, VARCEL
Symptoms: Dermatitis bullous, Drug ineffective, Infection, Nausea
Clinical narrative: p/vax pt nauseated;3 days later started breaking out w/varicella lesions;estimated 70-100 lesions;no tx other than letting disease run its course;
Age: 36.0
Sex: M
Vaccine: VARCEL, VARCEL
Symptoms: Dermatitis bullous, Infection, Myalgia, Pruritus, Pyrexia
Clinical narrative: pt devel chickenpox;fever 9-101.2, achiness, rash blistered 200+ lesions, breaking, itchy rash on upper torso, arms & one on cheek;
Age: 36.0
Sex: M
Vaccine: VARCEL, VARCEL
Symptoms: Rash
Clinical narrative: pt devel chickenpox;fever 9-101.2, achiness, rash blistered 200+ lesions, breaking, itchy rash on upper torso, arms & one on cheek;
Age: 32.0
Sex: F
Vaccine: HEP, VARCEL, HEP, VARCEL
Symptoms: Asthenia, Lymphadenopathy, Rash, Vasodilatation
Clinical narrative: p/vax pt felt hot noc of 6/8/99 & felt weak 6/9/99;devel bumps & blisters on back 6/11/99 2 inches below lt scapula 20mm size & pain under lt axilla & lt shoulder;took DPH;
Age: 5.0
Sex: F
Vaccine: DTAP, MMR, DTAP, IPV, MMR, VARCEL
Symptoms: Coma, Convulsion, Diarrhoea, Muscle twitching, Pain
Clinical narrative: This child presented with altered mental status on day of admission. She had received vaxs on 02/18. Two days post vax, she was heard to make an unusual noise in the morning while asleep. Her mother went in to check on her and noted that she was unresponsive with glossy eyes. This lasted 1-2 minutes. She continued to be unresponsive for 10 minutes post the initial 2 minutes. She was subsequently sleepy and had poor balance when standing. She went to sleep shortly afterwards and was noted to have right hand twitching while asleep. Pt was seen by physician who noted that she was uncoordinated and needed support while sitting. She was admitted through the ER for observation. She was slightly confused but coherent. She had experienced pain at injection site after vax and was treated with Tylenol. Physician noted that she probably experienced partial complex seizure.   A follow up report received 6/12/2000 adds: Spoke to parent of pt - Child has recovered except for occasional fatigue and stomach aches in the morning (and occasional muscle pain). Consent form sent so we can obtain hospital discharge summary. Another follow up report received 6/12/2000 acknowledges receipt of signed consent form.
Age: 5.0
Sex: F
Vaccine: DTAP, MMR, DTAP, IPV, MMR, VARCEL
Symptoms: Pyrexia, Staring, Stomach discomfort, Vomiting
Clinical narrative: This child presented with altered mental status on day of admission. She had received vaxs on 02/18. Two days post vax, she was heard to make an unusual noise in the morning while asleep. Her mother went in to check on her and noted that she was unresponsive with glossy eyes. This lasted 1-2 minutes. She continued to be unresponsive for 10 minutes post the initial 2 minutes. She was subsequently sleepy and had poor balance when standing. She went to sleep shortly afterwards and was noted to have right hand twitching while asleep. Pt was seen by physician who noted that she was uncoordinated and needed support while sitting. She was admitted through the ER for observation. She was slightly confused but coherent. She had experienced pain at injection site after vax and was treated with Tylenol. Physician noted that she probably experienced partial complex seizure.   A follow up report received 6/12/2000 adds: Spoke to parent of pt - Child has recovered except for occasional fatigue and stomach aches in the morning (and occasional muscle pain). Consent form sent so we can obtain hospital discharge summary. Another follow up report received 6/12/2000 acknowledges receipt of signed consent form.
Age: 5.0
Sex: F
Vaccine: DTAP, MMR, DTAP, IPV, MMR, VARCEL
Symptoms: Balance disorder, Coma, Confusional state, Convulsion, Coordination abnormal
Clinical narrative: This child presented with altered mental status on day of admission. She had received vaxs on 02/18. Two days post vax, she was heard to make an unusual noise in the morning while asleep. Her mother went in to check on her and noted that she was unresponsive with glossy eyes. This lasted 1-2 minutes. She continued to be unresponsive for 10 minutes post the initial 2 minutes. She was subsequently sleepy and had poor balance when standing. She went to sleep shortly afterwards and was noted to have right hand twitching while asleep. Pt was seen by physician who noted that she was uncoordinated and needed support while sitting. She was admitted through the ER for observation. She was slightly confused but coherent. She had experienced pain at injection site after vax and was treated with Tylenol. Physician noted that she probably experienced partial complex seizure.   A follow up report received 6/12/2000 adds: Spoke to parent of pt - Child has recovered except for occasional fatigue and stomach aches in the morning (and occasional muscle pain). Consent form sent so we can obtain hospital discharge summary. Another follow up report received 6/12/2000 acknowledges receipt of signed consent form.
Age: 5.0
Sex: F
Vaccine: DTAP, MMR, DTAP, IPV, MMR, VARCEL
Symptoms: Injection site pain, Muscle twitching, Somnolence, Staring
Clinical narrative: This child presented with altered mental status on day of admission. She had received vaxs on 02/18. Two days post vax, she was heard to make an unusual noise in the morning while asleep. Her mother went in to check on her and noted that she was unresponsive with glossy eyes. This lasted 1-2 minutes. She continued to be unresponsive for 10 minutes post the initial 2 minutes. She was subsequently sleepy and had poor balance when standing. She went to sleep shortly afterwards and was noted to have right hand twitching while asleep. Pt was seen by physician who noted that she was uncoordinated and needed support while sitting. She was admitted through the ER for observation. She was slightly confused but coherent. She had experienced pain at injection site after vax and was treated with Tylenol. Physician noted that she probably experienced partial complex seizure.   A follow up report received 6/12/2000 adds: Spoke to parent of pt - Child has recovered except for occasional fatigue and stomach aches in the morning (and occasional muscle pain). Consent form sent so we can obtain hospital discharge summary. Another follow up report received 6/12/2000 acknowledges receipt of signed consent form.
Age: 4.0
Sex: M
Vaccine: MMR, VARCEL, VARCEL
Symptoms: Infection, Pyrexia
Clinical narrative: On June 8, 1999 the pt developed a varicella like rash.
Age: 4.0
Sex: M
Vaccine: MMR, VARCEL, VARCEL
Symptoms: Dermatitis bullous
Clinical narrative: On June 8, 1999 the pt developed a varicella like rash.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Alanine aminotransferase increased, Arthralgia, Blood disorder, Blood lactate dehydrogenase increased, Blood uric acid increased
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Night sweats, Pyrexia, Red blood cell sedimentation rate increased, Serum sickness, Upper respiratory tract infection
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Urticaria, Vomiting, White blood cell count increased
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Arthralgia, Autoimmune disorder, Blood lactate dehydrogenase increased, Blood uric acid increased, Crohn's disease
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Joint swelling, Lymphadenopathy, Night sweats, Pyrexia, Rash papular
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Red blood cell sedimentation rate increased, Serum sickness, Upper respiratory tract infection, Urticaria, Vasculitis
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 16.0
Sex: M
Vaccine: HEP, HIBV, TD, HEP, HIBV, TD
Symptoms: Vomiting, Wegener's granulomatosis, White blood cell count increased
Clinical narrative: This 16 year old male, returned to physician 4 days post vax (04/17) with urticarial rash and was place on Benadryl and Prednisone 20mg PO bid. On 04/18, there was no rash but he presented with arthralgias of his knees, hips, elbows and shoulders. He was dxed with serum sickness and increase his Prednisone to 20mg PO tid and added Ibuprofen 400 PO tid and continued Benadryl. On 04/20, his joints were normal but again had urticaria. Prednisone and Ibuprofin were continued. Cyproheptadine, 4 mg PO qid was substituted for the Benadryl. Prednisone was stopped 04/22 and when he began to experience joint pains again was resumed at same dose and frequency. 04/25 Urticarial rash present but joints normal and began to taper prednisone over 3-4 days. 04/28 pt developed fever of 101, no rash, mild ankle and wrist pain, moderate shoulder and knee pain but no visible swelling. Labs were conducted. Referred to pediatric rheumatologist. Suggestions were made to taper prednisone. 05/02 periorbital area showed urticaria and some shoulder pain. but otherwise a negative exam.  Medications were continued due to continuing symptoms. 05/10 Utricaria present on face, arms, legs, but no joint findings. Fever of 101 and URI symptoms were also present. More tests were conducted. Due to the elevated Uric Acid and LDH, further testing to rule out lymphoma, other malignancy, Autoimmune, Crohn's, Wegener's, Vasculitis, or tick born illness may be conducted. 05/12 intermittent fever of 101-102 for 2-3 days, vomiting for 1 day and night sweats. CT of chest and abdomen ruled out masses and abscesses, lymph nodes swollen. 05/15 pt noted fever, increase hip and joint pain, mild papular red blanching rash, joints puffy. Vaccines have not been ruled out as a causative connection. Diagnosis as per discharge summary is serum sickness.
Age: 37.0
Sex: M
Vaccine: TD, TD
Symptoms: Bradycardia, Chest pain, Headache, Hyperhidrosis
Clinical narrative: Within 20 minutes headache, chest pain, diaphoresis, bradycardia
Age: 37.0
Sex: M
Vaccine: TD, TD
Symptoms: Bradycardia, Chest pain, Headache, Hyperhidrosis, Sinus bradycardia
Clinical narrative: Within 20 minutes headache, chest pain, diaphoresis, bradycardia
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, DTAP, HEP
Symptoms: Acidosis, Anaemia, Bacterial infection, Blood potassium increased, Cardio-respiratory arrest
Clinical narrative: Pt died.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, DTAP, HEP
Symptoms: Disseminated intravascular coagulation, Encephalopathy, Hypoxia, Pneumonia, Pulse absent
Clinical narrative: Pt died.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, DTAP, HEP
Symptoms: Viral infection
Clinical narrative: Pt died.
Age: 0.2
Sex: M
Vaccine: DTAP, HEP, DTAP, HEP
Symptoms: Unevaluable event
Clinical narrative: Pt died.
Age: 1.0
Sex: M
Vaccine: DTAP, HIBV, IPV, MMR, DTAP, HIBV, IPV, MMR
Symptoms: Convulsion, Pyrexia
Clinical narrative: Increased temp 103.6F, seizure activity to f/u with MD.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Rash
Clinical narrative: On May 28th 1999 the pt presented with fifteen lesions on his back and trunk. The MD prescribed oatmeal colloidal bath (Aveeno) and diphenhydramine HCI (Benadryl), and an antiviral agent. The patients brother had a similar experience following exposure to varicella.
Age: 28.0
Sex: F
Vaccine: VARCEL
Symptoms: Blister, Impetigo, Rash, Skin ulcer
Clinical narrative: On May 26, 1999 the patient noticed a moist sore on the corner of her mouth and two crusty sores between the corner of mouth and her nose. On May 29, 1999 she noticed a small, opened blister on the back of her leg and a few fluid red spots on the left side of her face in patch formation. On May 31, 1999 her facial rash started moving down her jaw line and back to her physician and treated with antibiotics, phisodex scrub, a soaking solution, and a dermatology salve. The MD felt that the pt's condition was not chickenpox as the rash was not symmetrical and she was dx with blistering impetigo. By the middle of July 1999, the pt's rash had completely resolved.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 19, 1999 the patient was dx with chickenpox following a MD visit.
Age: 12.0
Sex: F
Vaccine: HEP, TD, VARCEL
Symptoms: Asthenia, Pain
Clinical narrative: On May 11, 1999 the pt experienced arm pain just above the elbow. On 06/01/1999 she sought medical attention, she was treated with ibuprofen, heat on the arm, and vitamins with iron. On May 28, 1999 the pt was advised by MD to take acetaminophen. On June 2, 1999 the pt's mother reported that her arm condition had improved her pain was subsiding, and her grasp was stronger. She continued to take ibuprofen. The mother also stated that the pt would follow through with OVA testing, and with vitamin therapy. On Jun 8, the student complained of some soreness above and below the right elbow. Her grasp was not as strong, but she could write. On June 4th and 5th 1999 the pt's father indicated that her arm condition was fine, able to move freely with no pain or weakness.
Age: 5.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Pruritus, Rash erythematous
Clinical narrative: On May 29, 1999 the pt developed a red raised rash on the face, neck, trunk and extremities. The child also experienced itching. On May 31, 1999 the child was presented the ER with sx. Upon admission the child was dx wit chickenpox. Advised to F/U with local MD.
Age: 1.75
Sex: F
Vaccine: MMR, OPV, VARCEL
Symptoms: Herpes zoster, Infection, Rash
Clinical narrative: On June 2, 1999 the pt developed herpes zoster that consisted of a typical rash on right distribution on back along dermatone to mid line. It was toted that no rash occured at the site of injection post vax and the rash did not occur within 42 days of vax. The pt presented to a MD at which time the papular lesions were scanned. Not recently exposed to chickenpox or shingles.
Age: 1.0
Sex: F
Vaccine: VARCEL
Symptoms: Pyrexia, Rash papular
Clinical narrative: On May 20, 1999 the pt experienced a high fever of 101F which persisted for days. On May 21, 1999 the rash was generalized, fine, and papular. The skin very red, and there were red bumps in all her hot spots, on stomach, neck, ears, under her arms, and inside her elbows. On 06/01/1999 the pt was afebile, but the rash was increased. The pt was taken to MD seven times, and was taken to a dermatologist. No dx was made. The pt was treated with cortisone cream and antihistamines. Subsequently, the pt recovered from the fever. Follow up was received from MD. Referred to a allergist.
Age: 6.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Rash
Clinical narrative: There was no concomitant medication. On 06/01/1999 the pt broke out in varicella with 15 lesions. There was no fever associated with her rash. Follow up states on 08/21/2000 the patient again broke out with chicken pox. About 30-40 lesions were noted. Subsequently the patient recovered. No further information is expected.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Skin ulcer
Clinical narrative: On May 29, 1999 the patient experienced chickenpox with > 70 lesions.
Age: 1.08
Sex: F
Vaccine: VARCEL
Symptoms: Pyrexia, Rash
Clinical narrative: On approximately May 20, 1999, the pt developed rash with fever of 103F.
Age: 32.0
Sex: F
Vaccine: VARCEL
Symptoms: Arthralgia
Clinical narrative: The administering nurse tried to administer the frozen vax into the patients arm and had to pull out the needle, warmed the vax in his hand, and re-administered it. The medical technologist was not able to administer all of it since some of the vax was still frozen. On May 26, 1999, the pt experienced pain in the left shoulder. Follow-up was received from a woman from a MD's office. The pt was also concerned that the vax was reconstituted longer than 30 minutes and refrozen.
Age: 4.0
Sex: F
Vaccine: VARCEL
Symptoms: Skin ulcer
Clinical narrative: On May 17, 1999 the pt experienced 30-50 lesions all over her body which lasted 5 days. The pt sought unspecified medical treatment.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Herpes zoster, Infection
Clinical narrative: On approximately May 19, 1999 the pt experienced shingles on the upper arm which subsequently became infected. The pt was treated with antibiotics.
Age: 1.5
Sex: M
Vaccine: DT, HIBV, MMR, OPV, VARCEL
Symptoms: Infection, Pyrexia, Skin ulcer
Clinical narrative: Subsequently the pt experienced a varicella like rash. The reporter noted three episodes of full blown varicella lesions. The pt sought treatment, follow up information from RN reported that on April 30, 1999 the pt's mother called the physician's office to report that the pt had developed approximately thirty generalized lesions. The patient had no other reported sx.  Approximately two weeks post vax, the pt mother again called the physician's office to report that he has another eruption of approximately thirty generalized lesions. Additionally the pt had a low grade fever. On Jun 2, 1999, the pt again experienced and eruption of thirty lesions and was seen by MD. The pt was diagnosed with Varicella.
Sex: F
Vaccine: VARCEL
Symptoms: Nausea, Pruritus, Pyrexia, Skin ulcer, Vomiting
Clinical narrative: Information received from a health care professional concerning a female who was exposed to her daughter who was vax with one dose of varicella virus live. Subsequently the pt developed greater than 25 lesions but less than 50 approximately 22 days after her daughter was vaccinated with varicella. The mother had no known exposure to wild type chickenpox. The child did not have a post vax rash. Twenty one days after the child's vax, the mother developed a fever of 102 nausea, vomiting, and pruritus all of which lasted approximately 5 days.
Age: 1.2
Sex: F
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Pruritus
Clinical narrative: Information had been received from a physician concerning female, who in April 1999 was vax with varicella, concomitant therapy included cisapride and cimetidine. On June  2, 1999, the pt experienced a varicella like rash consisting of approximately 7 pustular lesions on the chest but no fever. The patient also experienced itching.
Age: 3.0
Sex: M
Vaccine: VARCEL
Symptoms: Dermatitis bullous, Injection site rash
Clinical narrative: On June 2, 1999 the pt experienced a varicella rash with 8-10 spots on the stomach and chest, 4-5 spots on the arms, and 2-4 on the legs. The spots appeared like bites. There were also two spots near the injection site.
Age: 1.0
Sex: F
Vaccine: VARCEL
Symptoms: Rash macular
Clinical narrative: Subsequently the pt developed 3 blotches on her chest.
Age: 9.0
Sex: F
Vaccine: HEP, VARCEL
Symptoms: Lacrimation increased, Nausea, Pharyngitis, Pyrexia, Rash
Clinical narrative: On May 17, 1999 the pt developed watery eyes which the pt mother attributed to cold sx. On the evening of May 19, 1999 the pt developed a fever, of 102.4F Within 24 hours the pt broke out with 2 pox which were not fluid filled. The pt also became nauseated. By May 24, 1999 the pt had broken out with pustules in the mouth and some of the lesions were noted to be in the ear canal and on the ear drum. The pt was treated with amoxicillin trihydrate. The reporter believed there was no association between the pt sx and the vax, however, the pt experience was considered an other medical event.
Age: 9.0
Sex: F
Vaccine: HEP, VARCEL
Symptoms: Rash pustular, Rhinitis
Clinical narrative: On May 17, 1999 the pt developed watery eyes which the pt mother attributed to cold sx. On the evening of May 19, 1999 the pt developed a fever, of 102.4F Within 24 hours the pt broke out with 2 pox which were not fluid filled. The pt also became nauseated. By May 24, 1999 the pt had broken out with pustules in the mouth and some of the lesions were noted to be in the ear canal and on the ear drum. The pt was treated with amoxicillin trihydrate. The reporter believed there was no association between the pt sx and the vax, however, the pt experience was considered an other medical event.
Age: 19.0
Sex: M
Vaccine: VARCEL
Symptoms: Rash
Clinical narrative: On June 4th 1999 the pt developed possible chickenpox with a small area of rash and a lesion on his arm that did not look like a vesicle. The pt was afebrile. There was no pruritus or drainage.
Age: 5.0
Sex: M
Vaccine: VARCEL
Symptoms: Rash
Clinical narrative: Subsequently the pt experienced a breakthrough rash with less than 50 lesions. Unspecified medical attention was sought.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Rash, Rash papular, Rash vesicular, Skin ulcer
Clinical narrative: Subsequently the patient developed rash with approximately 10 lesions characterized by papular eruption with vesiculation. It was indicated that the pt was afebrile. MD believed there was an association between the pt sx and vax. No speciman will be forthcoming from this case.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Rash, Skin ulcer
Clinical narrative: On June 2, 1999 the pt developed rash with easily over 100 lesions. It was noted that the pt was afebrile. Additional information obtained indicated that the pt recovered from episode.
Age: 2.9
Sex: F
Vaccine: VARCEL
Symptoms: Rash papular, Rash pustular, Skin ulcer
Clinical narrative: On June 3, 1999 the pt developed approximately fifty lesions all over body, no fever. The lesions started on chest and then spread peripherally. Rash was generalized, erythematous, papular and pustular with one or two crusting lesions.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On June 2, 1999 the pt developed chickenpox.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Herpes zoster, Infection
Clinical narrative: On June 1, 1999 the pt developed shingles in her right leg and buttocks. The pt was presented to a physician with symptoms. It was that the pt experienced leg pain two weeks prior to the episode. Reporter believed there was no association with pts sx and vax.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Fatigue, Infection
Clinical narrative: On May 20, 1999 the patient experienced chickenpox. The pt was afebrile and tired. No further information is available.
Age: 1.5
Sex: F
Vaccine: VARCEL
Symptoms: Febrile convulsion, Pyrexia, Rash, Rash macular
Clinical narrative: On May 29, 1999 the patient developed breakthrough varicella with two pink macules on her left arm near the injection site and fever of 104F. In addition the pt experienced febrile seizure and was taken to the ER. Treatment with acetaminophen, ibuprofen, and fluids was initiated and followed by resolution of symptoms. Upon medical review, the pt febrile seizure was considered an important medical event. On May 14, 1999 the pt developed a fever of 102F lasting one day and had a possible rash at site. On May 29, 1999 the pt did experience febrile seizures and was hospitalized overnight and treated with lorazepam.
Age: 4.0
Sex: M
Vaccine: VARCEL
Symptoms: Blister, Pyrexia
Clinical narrative: On May 27, 1999 the pt developed less than 15 fluid-filled spots with low-grade temperature. Treatment with the following acetaminophen, diphenhydramine hydrochloride, aveeno baths and fluids were initiated.
Age: 3.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 19, 1999 the pt developed chickenpox with approximately nine lesions. The reporter believed there was no association between the pt sx and the vax. A visit to a physician or to the emergency room was required.
Age: 4.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On May 25, 1999 the pt developed chickenpox with less than 50 lesions. Subsequently, the patient recovered from the episode.
Sex: F
Vaccine: VARCEL
Symptoms: Abdominal distension, Herpes zoster, Infection, Pain, Pyrexia
Clinical narrative: On Feb 23, 1999 female was exposed to her significant other who developed chicken pox but was misdiagnosed. On Feb 26, 1999 her significant other was seen by a dermatologist and this time dx with chickenpox. On Mar. 10, 1999 vaccinated, subsequently she developed a fever of 102F and rash with 12 lesions. She stated that the varicella rash started on her chest then spread everywhere, including her throat. Several weeks later, she developed severe shingles, a strange tremor, left sided pain and abdominal distension. She sought medical attention and was treated with famciclovir. The women denied having a culture of lesions taken.
Sex: F
Vaccine: VARCEL
Symptoms: Rash, Tremor
Clinical narrative: On Feb 23, 1999 female was exposed to her significant other who developed chicken pox but was misdiagnosed. On Feb 26, 1999 her significant other was seen by a dermatologist and this time dx with chickenpox. On Mar. 10, 1999 vaccinated, subsequently she developed a fever of 102F and rash with 12 lesions. She stated that the varicella rash started on her chest then spread everywhere, including her throat. Several weeks later, she developed severe shingles, a strange tremor, left sided pain and abdominal distension. She sought medical attention and was treated with famciclovir. The women denied having a culture of lesions taken.
Age: 1.2
Sex: F
Vaccine: MMR, VARCEL
Symptoms: Herpes zoster, Infection
Clinical narrative: On Feb 14, 1999 the pt developed chickenpox. On June 2, 1999 the pt was diag with shingles. The shingles developed on the left mediothoracic area following the chest wall line. The pt maximum temp during herpes zoster was 98.6F. The pt did not have other systemic symptoms. On a scale of one through ten, ten being the worse, the pt was quantified as a 2.
Age: 21.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: Lack of response.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection
Clinical narrative: On June 1, 1999 the pt developed atypical chickenpox.
Age: 6.0
Sex: M
Vaccine: VARCEL
Symptoms: Drug ineffective, Infection, Rash
Clinical narrative: On June 5, 1999 the pt experienced a mild case of varicella with about thirty bumps, located  mainly on his trunk.
Age: 32.0
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: In 1996, pt was vaccinated with 2 doses of varicella virus vaccine live, within a 5 week period and subsequently, she sought medical attention and a serum VZV antibody test revealed a lack of seroconversion. No further information is available.
Sex: F
Vaccine: VARCEL
Symptoms: Drug ineffective
Clinical narrative: A pt was vaccinated with a 1st and 2nd dose of varicella virus vaccine live in March and May of 1998, respectively. After each dose, the pt's varicella antibody titers were low. The pt's employer requires that the titer be greater than 1.9. Additional information has been requested.