Age: 68.0
Sex: F
Vaccine: COVID19
Symptoms: Arthralgia, Inflammation, Insomnia, Joint swelling, Pain
Clinical narrative: excruciating pain.; excruciating pain in hip and leg, every time she got doses of  Pfizer BioNTech Covid-19 vaccine.; excruciating pain in hip and leg, every time she got doses of  Pfizer BioNTech Covid-19 vaccine.; sore arm, that she had with each dose; leg inflammation; she couldn't even sleep; swelling in the right ankle; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 70-year-old female patient received BNT162b2 (BNT162B2), on 08Feb2021 as dose 1, single (Lot number: EN6201) at the age of 68 years for covid-19 immunisation. The patient's relevant medical history included: "High cholesterol" (unspecified if ongoing); "for sugar, is pre diabetic" (unspecified if ongoing); "high blood pressure" (unspecified if ongoing); "for sleep" (unspecified if ongoing); "Nerve pain" (unspecified if ongoing); "Has spinal stenosis" (unspecified if ongoing); "Hip pain" (unspecified if ongoing); "arthritis" (unspecified if ongoing); "steroid" (unspecified if ongoing), notes: Only thing she had was steroid injection at hip,; "PTSD" (unspecified if ongoing). Concomitant medication(s) included: GABAPENTIN taken for neuralgia, spinal stenosis (ongoing); LISINOPRIL taken for hypertension (ongoing); METFORMIN taken for glucose tolerance impaired (ongoing); ROSUVASTATIN taken for blood cholesterol increased (ongoing); XANAX taken for sleep disorder (ongoing). Vaccination history included: Tetanus (Normally, does not get bad reactions.), when the patient was 19 years old, for Immunization, reaction(s): "arm hurt and couldn't move it for a month"; Tetanus, for Immunization, reaction(s): "arm hurt and couldn't move it for a month". The following information was reported: PAIN IN EXTREMITY (non-serious), ARTHRALGIA (non-serious) all with onset 2021, outcome "not recovered" and all described as "excruciating pain in hip and leg, every time she got doses of Pfizer BioNTech Covid-19 vaccine."; PAIN (medically significant) with onset 2021, outcome "not recovered", described as "excruciating pain."; INFLAMMATION (non-serious) with onset 2021, outcome "unknown", described as "leg inflammation"; INSOMNIA (non-serious) with onset 2021, outcome "unknown", described as "she couldn't even sleep"; PAIN IN EXTREMITY (non-serious) with onset 2021, outcome "recovered", described as "sore arm, that she had with each dose"; JOINT SWELLING (non-serious) with onset 2021, outcome "unknown", described as "swelling in the right ankle". The events "excruciating pain.", "excruciating pain in hip and leg, every time she got doses of pfizer biontech covid-19 vaccine.", "sore arm, that she had with each dose", "leg inflammation", "she couldn't even sleep" and "swelling in the right ankle" required physician office visit. The patient underwent the following laboratory tests and procedures: Antibody test: gone down to 800.; Antinuclear antibody: Normal; Blood cholesterol: High; Blood pressure measurement: High; Blood test: Good; Fine, notes: Regular blood work was fine; Magnetic resonance imaging: Fine, notes: everything was fine; Red blood cell sedimentation rate: normal; X-ray: Fine, notes: everything was fine. Therapeutic measures were taken as a result of pain, pain in extremity, arthralgia, pain in extremity, inflammation, insomnia, joint swelling.  Clinical course: Patient took Rosuvastatin, which was generic for Crestor, been taken from years,.Metformin she had been taking like 15 years and has never been full diabetic. Patient already had hip issues, she had to get hip replacement an already had some pain in that hip. After she got first dose, had slightly sore arm, that she had with each dose. Hip and leg issues didn't seem to go away with first dose. Was so sore, she couldn't even sleep, even with taking Hydrocodone. Entire leg was inflamed, had to sleep with 3 ice packs on leg. By the time she had surgery, hip surgery, 15Mar2021, she was ready for them to chop her leg off. Thought she had PTSD (Post-traumatic stress disorder) from it. The booster dose was given 6 months post op in Oct2021. The same symptoms occurred again with the booster dose. Patient reported issues with excruciating pain in hip and leg, every time she got doses of Pfizer BioNTech Covid-19 vaccine. Patient had this pain within a few days of second dose, she states that it happened after first dose as well. She could tell from the calendar dates, when she saw the surgeon and when she got the vaccine. Within 8 or 9 days back there, after the steroid shots wore off, she couldn't even sleep. The first 2 shots were 3 weeks a part. She does not remember any relief during that 3 week period, it just was excruciatingly painful. Even had swelling in the right ankle. Hip surgeon said it was not coming from her hip. Pain was in entire right leg, down to the ankle. Treatment: Had Hydrocodone left over from surgery, that she took. The first time this happened, before the surgery, they gave her Tramadol, that did absolutely nothing. Just suffered the 6 weeks until she had the surgery. Patient took a lot of medications. Patient had no prior vaccinations (within 4 weeks). Only thing she had was steroid injection at hip, probably, maybe 6 weeks prior to getting Covid vaccinations. They said she had to wait because, that would suppress the immune response, or whatever. There was no family Medical History Relevant to Adverse Events. She only had a slightly sore arm at first with each dose but within a few days of each dose the hip pain and leg inflammation started. The hip/leg pain didn't completely go way after the first dose.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202300080140 Same patient/drug and different doses;US-PFIZER INC-202300080141 Same patient/drug and different doses;