Age: 70.0
Sex: M
Vaccine: COVID19
Symptoms: Decreased insulin requirement, Fatigue, Therapeutic response unexpected
Clinical narrative: Noticed another significant improvement in my stamina and alertness; In recent weeks my need for insulin as been cut in half and still going down further; I suffer from Chronic Fatigue, so it is unusual for me to feel exhausted after certain injections. The exhaustion lasted two days/suffering for two days with exhaustion from the vaccine; This spontaneous case was reported by a patient and describes the occurrence of THERAPEUTIC RESPONSE UNEXPECTED (Noticed another significant improvement in my stamina and alertness), DECREASED INSULIN REQUIREMENT (In recent weeks my need for insulin as been cut in half and still going down further) and FATIGUE (I suffer from Chronic Fatigue, so it is unusual for me to feel exhausted after certain injections. The exhaustion lasted two days/suffering for two days with exhaustion from the vaccine) in a 70-year-old male patient who received mRNA-1273.815 (SPIKEVAX 2023-2024) for COVID-19 prophylaxis.     The patient's past medical history included Bedridden and Gait disturbance. Concurrent medical conditions included Chronic fatigue syndrome (Chronic fatigue immune dysfuction syndrome), Cerebral disorder (fogged brain, searching for words and difficulty with simple math), Memory loss and Diabetic (Patient was on insulin and in recent weeks his need for insulin has been cut in half and still going down further.). Concomitant products included INSULIN for Diabetic.    On 26-Sep-2023, the patient received dose of mRNA-1273.815 (SPIKEVAX 2023-2024) (Intramuscular use) 1 dosage form. On 27-Sep-2023, the patient experienced DECREASED INSULIN REQUIREMENT (In recent weeks my need for insulin as been cut in half and still going down further) and FATIGUE (I suffer from Chronic Fatigue, so it is unusual for me to feel exhausted after certain injections. The exhaustion lasted two days/suffering for two days with exhaustion from the vaccine). On an unknown date, the patient experienced THERAPEUTIC RESPONSE UNEXPECTED (Noticed another significant improvement in my stamina and alertness). On 28-Sep-2023, DECREASED INSULIN REQUIREMENT (In recent weeks my need for insulin as been cut in half and still going down further) and FATIGUE (I suffer from Chronic Fatigue, so it is unusual for me to feel exhausted after certain injections. The exhaustion lasted two days/suffering for two days with exhaustion from the vaccine) had resolved. At the time of the report, THERAPEUTIC RESPONSE UNEXPECTED (Noticed another significant improvement in my stamina and alertness) outcome was unknown.            Treatment medications was not reported.  After Spikevax administration on 26-Sep-2023, the patient had noticed another significant improvement in stamina and alertness. The patient felt it was important for research in the area of vaccine and the effect on chronic fatigue dysfunction syndrome.   This case was linked to MOD-2022-583908 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 13-Nov-2023: Significant follow-up received on 13-NOV-2023: Reporter details, Patient details, Medical history, Route of Administration, Concomitant medication, Events and narrative were updated.