Age: 20.0
Sex: F
Vaccine: HPV4
Symptoms: Loss of personal independence in daily activities, Migraine, Mobility decreased, Muscle spasms, Peripheral swelling
Clinical narrative: Autoimmune Injuries; POTS/autonomic injuries/weakness, numbness in the legs, arms, and neck, difficulty moving, pain in lower back, muscle spasms, swelling in legs, chest pains, shortness of breath, fatigue, lightheadedness, dizziness, neurogenic syncope, brain fog with; neurological injuries; Information has been received from a lawyer regarding a case in litigation and referred to a currently adult female patient (pt) (currently 24 years old). Her other medical history, concurrent conditions and concomitant therapies were not provided. On 29-JUL-2020 (at the age of 20 years old), the pt was vaccinated with the first dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot # and expiration date was not provided), as recommended by her health care provider/doctor, with her consent, for prophylaxis (reported as for preventing cervical cancer). On 15-SEP-2020 (at the age of 20 years old), the pt was vaccinated with the second dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot # and expiration date was not provided). On 19-FEB-2021 (at the age of 21 years old), the pt was vaccinated with the third dose of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) intramuscular injection (exact dose, route of administration, anatomical location, lot # and expiration date was not provided). Following the third quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) vaccination, patient experienced, and continued to experience weakness, numbness in the legs, arms, and neck. Patient frequently experienced difficulty moving due to persistent pain in her lower back, muscle spasms, and unusual swelling in her legs. Patient also experienced chest pains, shortness of breath, fatigue, lightheadedness, dizziness, neurogenic syncope, brain fog with garbled speech, migraines, and gait instability. Furthermore, patient experienced heat, cold, and exercise intolerance. patient was photogenic sensitive to flashing lights, and sometimes experienced blank stare seizure-like episodes. In the summer of 2024, patient was diagnosed with postural orthostatic tachycardia syndrome (POTS). As the months progressed, so did her injuries. She was seen by multiple physicians and specialists for her complaints which now included: weakness, numbness in the legs, arms, and neck, difficulty moving, pain in lower back, muscle spasms, swelling in legs, chest pains, shortness of breath, fatigue, lightheadedness, dizziness, neurogenic syncope, brain fog with garbled speech, migraines, gait instability, heat, cold, and exercise intolerance, photogenic sensitive to flashing lights, blank stare seizure-like episodes, and postural orthostatic tachycardia syndrome (POTS). As a result of her post- quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, patient had been unable to engage in activities that a normal young person would enjoy. Post quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL)-injection, patient was unable to go on long distance walks or runs and her physical limitations had negatively impacted her abilities to continue her responsibilities to care for her pets, do household chores, or socialize. Based upon her chronic and severe post-quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) symptoms, patient had been diagnosed with various medical conditions, including but not limited to, postural orthostatic tachycardia syndrome (POTS). Patient contended that her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) injections caused her to develop serious and debilitating autoimmune, autonomic, and neurological injuries, including but not limited to postural orthostatic tachycardia syndrome (POTS), as well as a constellation of adverse symptoms, complications, injuries, and other adverse events, many of which were alleged herein and all of which were caused by quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL) or otherwise linked to her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL)-induced autoimmune disorder. As a proximate result of quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL), the patient had suffered and continued to suffer severe and permanent physical injuries and associated symptomatology and had suffered severe and permanent emotional injuries, including pain and suffering. She also had a substantial fear of suffering additional and ongoing harms, including but not limited to now being at an increased risk of cancer, and future symptoms and harms associated with her injuries caused by quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL). As a direct and proximate result of her quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL)-induced injuries, the patient suffered and continued to suffer economic losses, including considerable financial expenses for medical care and treatment, and diminished income capacity, and she would continue to incur these losses and expenses in the future. The outcome of all events was considered to be not recovered. The lawyer considered all events to be related to quadrivalent human papillomavirus (Types 6,11,16,18) recomb. vaccine (GARDASIL).  The lawyer considered all events to be disabling.  Upon internal review, the event autoimmune disorder was determined as medically significant.