Age: 62.0
Sex: F
Vaccine: COVID19
Symptoms: Bursitis, Computerised tomogram, Condition aggravated, Diabetes mellitus, Diabetic gastroparesis
Clinical narrative: Infection and inflammatory response in her foot in late Summer/ Early Fall in her middle 3rd toe on her left foot- Infected toe; inflammation in her tendons and ligaments is much worse; inflammation in her tendons and ligaments is much worse; left hip inflammation and arthritis/ it is the bursa/ problems with her joints; left hip inflammation and arthritis/ it is the bursa/ problems with her joints; condition aggravated; has always struggled with blood sugar, and since all of this it has always been that much harder to control blood sugar and it has been very high for quite some time; Lichen sclerosus (which existed before the vaccine/after vaccine had a horrible flare up that was off the charts); gastroparesis (existed before vaccine, much worse after vaccine due to inflammatory response) due to her diabetes is so bad; Enlarged Liver; Lichen planus; Panniculitis; inflammation in tendons and ligaments is much worse/escalation in body aches, pains, inflammatory responses, new autoimmune issues/Inflammation Left Hip hip has been so bad/arthritis; Hyperplasia of both adrenal gland; Woke up with trigger finger of her middle finger on the left hand; lifted something and heard a crunch and pop in right upper arm in the muscle and tore a muscle/Popeye muscle; Glaucoma/ only gotten worse/ pressure in her right eye has been uncontrollable; mass at the incision site on right breast/discovered it was fat necrosis/mass was benign; Neuropathy in her legs, feet and hands, been progressively worsening; Questionable lab work that is pointing to systemic lupus erythematosus; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 62 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 27Mar2021 (Lot number: ER2613, Expiration Date: Jul2021) at the age of 62 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Obese" (ongoing), notes: Obese; "Diabetic" (ongoing); "Sjogren's syndrome" (ongoing); "Basal Duct Metastatic Breast Cancer/invasive ductal malignant stage 2 breast cancer", start date: Oct2019 (ongoing); "Glaucoma" (ongoing); "Lichen sclerosus" (ongoing); "Gastroparesis" (ongoing); "neuropathy in her legs, feet and hands" (ongoing); "radiation treatment" (unspecified if ongoing), notes: followed every 3 months by an oncologist; "systemic lupus erythematosus" (unspecified if ongoing), notes: 25-30 years ago; "injury to her left hip" (unspecified if ongoing), notes: 25 years ago in her back yard. Cortisone injections fixed that; "fall" (unspecified if ongoing), notes: 25 years ago in her back yard. Cortisone injections fixed that; "terrible bruising in her left hip joint in the bursa" (unspecified if ongoing), notes: 25 years ago in her back yard. Cortisone injections fixed that. There were no concomitant medications. Past drug history included: Cortisone for hip injury. The following information was reported: LOCALISED INFECTION (hospitalization) with onset 2021, outcome "recovered" (2021), described as "Infection and inflammatory response in her foot in late Summer/ Early Fall in her middle 3rd toe on her left foot- Infected toe"; SYSTEMIC LUPUS ERYTHEMATOSUS (medically significant) with onset 2021, outcome "not recovered", described as "Questionable lab work that is pointing to systemic lupus erythematosus"; PANNICULITIS (medically significant) with onset Apr2021, outcome "not recovered", described as "Panniculitis"; SJOGREN'S SYNDROME (medically significant) with onset Apr2021, outcome "not recovered", described as "inflammation in tendons and ligaments is much worse/escalation in body aches, pains, inflammatory responses, new autoimmune issues/Inflammation Left Hip hip has been so bad/arthritis"; NEUROPATHY PERIPHERAL (medically significant) with onset 2021, outcome "not recovered", described as "Neuropathy in her legs, feet and hands, been progressively worsening"; HYPERPLASIA ADRENAL (medically significant) with onset Apr2021, outcome "not recovered", described as "Hyperplasia of both adrenal gland"; TRIGGER FINGER (medically significant) with onset 2021, outcome "recovered" (2021), described as "Woke up with trigger finger of her middle finger on the left hand"; MUSCLE RUPTURE (medically significant) with onset 2021, outcome "recovering", described as "lifted something and heard a crunch and pop in right upper arm in the muscle and tore a muscle/Popeye muscle"; GLAUCOMA (medically significant) with onset 2021, outcome "not recovered", described as "Glaucoma/ only gotten worse/ pressure in her right eye has been uncontrollable "; BREAST NECROSIS (medically significant) with onset 2021, outcome "unknown", described as "mass at the incision site on right breast/discovered it was fat necrosis/mass was benign"; DIABETES MELLITUS (medically significant) with onset Apr2021, outcome "not recovered", described as "has always struggled with blood sugar, and since all of this it has always been that much harder to control blood sugar and it has been very high for quite some time"; LICHEN SCLEROSUS (non-serious) with onset Apr2021, outcome "not recovered", described as "Lichen sclerosus (which existed before the vaccine/after vaccine had a horrible flare up that was off the charts)"; DIABETIC GASTROPARESIS (non-serious) with onset Apr2021, outcome "not recovered", described as "gastroparesis (existed before vaccine, much worse after vaccine due to inflammatory response) due to her diabetes is so bad"; HEPATOMEGALY (non-serious) with onset Apr2021, outcome "not recovered", described as "Enlarged Liver"; LICHEN PLANUS (non-serious) with onset Apr2021, outcome "not recovered", described as "Lichen planus"; LIGAMENTITIS (non-serious), TENDONITIS (non-serious), outcome "unknown" and all described as "inflammation in her tendons and ligaments is much worse"; ARTHRITIS (non-serious), BURSITIS (non-serious), outcome "unknown" and all described as "left hip inflammation and arthritis/ it is the bursa/ problems with her joints"; CONDITION AGGRAVATED (non-serious), outcome "unknown", described as "condition aggravated". The patient was hospitalized for localised infection (start date: 2021). The events "infection and inflammatory response in her foot in late summer/ early fall in her middle 3rd toe on her left foot- infected toe", "inflammation in tendons and ligaments is much worse/escalation in body aches, pains, inflammatory responses, new autoimmune issues/inflammation left hip hip has been so bad/arthritis", "hyperplasia of both adrenal gland", "woke up with trigger finger of her middle finger on the left hand", "lifted something and heard a crunch and pop in right upper arm in the muscle and tore a muscle/popeye muscle", "glaucoma/ only gotten worse/ pressure in her right eye has been uncontrollable ", "has always struggled with blood sugar, and since all of this it has always been that much harder to control blood sugar and it has been very high for quite some time" and "lichen planus" were evaluated at the physician office visit. The patient underwent the following laboratory tests and procedures: biopsy breast: (2021) discovered it was fat necrosis; blood cortisol: (Apr2021) elevated; blood glucose: (Apr2021) very high; computerised tomogram: (Apr2021) showed an inflammatory response, notes: there was inflammation and arthritis and it is the bursa; intraocular pressure test: (unspecified date) 38-42; investigation: (Apr2021) unknown results; laboratory test: (2021) pointing to systemic lupus erythematosus, notes: questionable lab work; (2021) pointed to sle 25-30 years ago, notes: lab work over the years; mammogram: (2021) discovered it was fat necrosis; saliva analysis: (Apr2021) unknown results; urine analysis: (Apr2021) unknown results. Therapeutic measures were taken as a result of localised infection, trigger finger, glaucoma. Reporter (patient) stated she reluctantly took the 2-part vaccine series in Mar2021 and Apr2021; she didn't want to take it, she was not well with a lot of things and she had a lot of concerns about possible side effects and she is 63-year-old, obese, diabetic, is recovering from Basal Duct Metastatic Breast Cancer, Sjogren's Syndrome and she had a lot going on. Over the last 10 months she had had an escalation in her illnesses. The patient reported had an escalation in body aches, pains, inflammatory responses, new autoimmune issues, and one thing after another. Caller states she has been saying after all of these things had been escalating, that the vaccine had really done something to her far and above over her normal crap she was dealing with before the vaccine. She had been diagnosed with an enlarged liver, panniculitis which is inflammation of the tissue around her abdomen, hyperplasia of both adrenal glands, lichen sclerosus (which existed before the vaccine, but it was not treated for years, and after the vaccine she had a horrible flare up that was off the charts), gastroparesis (which existed before the vaccine but is much worse after the vaccine due to the inflammatory response) due to her diabetes was so bad, inflammation in her tendons and ligaments is much worse, she had sores in her mouth and had been seen by dentists and an oral surgeon whom diagnosed the mouth sores as lichen planus. She had questionable lab work that is pointing to systemic lupus erythematosus, is it or isn't it? She was going to be seeing a rheumatologist in April for SLE. She had lab work over the years that pointed to SLE 25-30 years ago and now again her lab work was pointing that direction, stated she would know more when she saw the specialist in April. This all had been happening sense the vaccine. She woke up with trigger finger of her middle finger on the left hand one morning. The doctor treated it with cortisone. She was seen by an Orthopedic doctor for problems with her joints and she asked him about her finger, she told him she went to bed one night, and the next morning her middle finger on her left hand had trigger finger. She stated she didn't understand all of the inflammatory stuff, but he gave her an injection with cortisone in the Fall of last year (2021) after she suffered a couple of months and it took away pain from that. She had a CT of her left hip and it showed an inflammatory response. Shehad an injury to her left hip from a fall 25 years ago in her back yard that caused terrible bruising in her left hip joint in the bursa, but 25 years ago cortisone injections fixed that, but since she took the vaccine, her hip had been so bad. She  asked the Ortho doctor if he could do a CT or X-ray of the left hip and he informed her there was inflammation and arthritis and it is the bursa. She explained that since auto immune is part of her everyday it can attack the connective tissue and muscles out of nowhere, she lifted something and heard a crunch and pop in her right upper arm in the muscle and she tore a muscle and when she saw the shoulder specialist he called it a Popeye muscle after tore it out of nowhere. It was starting to resolve and heal, but out of blue she tore a muscle. She stated her body was under attack. She was hospitalized for an infection and inflammatory response in her foot in late Summer/ Early Fall (2021) in her middle 3rd toe on her left foot. She had to have IV antibiotics and was hospitalized for 5-6 days and then she had to go back for a week for outpatient antibiotics. The Nurse Practitioner said this had to be more of an inflammatory response to something so they requested a rheumatology consult but that happened after discharge. She also had Glaucoma and she has had multiple laser surgeries over the years and in this last 8,9,10 months it has only gotten worse since the vaccine. She reported she had issues with higher eye pressure before but once she took the vaccine the pressure in her right eye has been uncontrollable and she has seen doctors and tried many eye drops with no answer with the pressure as high as 38-42. So 4 weeks ago, she had had a major surgery in her right eye, they had to go in and put in a shunt and valve to get the pressure down so wouldn't lose her sight. She asked the eye doctor in January if it was inflammatory glaucoma and he was not sure at that time but certainly for whatever unknown reason nothing is helping it. Now after her surgery and she was recovering, the pressures are climbing again, and she may have to do another laser surgery with a heavy duty machine. She stated the doctor was waiting on a new machine or they may possibly have to go in and put in a larger shunt and drain more fluid down. The doctor had no answer but it had exponentially worsened. She stated none of the drops had helped; there had been so many different eye drops including methazolamide (GLAUCTABS), dorzolamide, brimonidine tartrate (ALPHAGAN), and pilocarpine as a last resort and there were 3-4 in between. Since the vaccine she used dorzolamide and pilocarpine. She stopped pilocarpine because she suffers from environmental acephalgic migraines and the pilocarpine just increased the headaches and it caused bad redness and burning in the eye; she was not going to take something that would add to that. The  surgeon stopped the pilocarpine quickly so her only option was the surgery, because nothing had helped her eye pressure. She had neuropathy in her legs, feet and hands; it was bad before, like bad, prior to taking the vaccine, but it has been progressively worsening, and now it was so exponentially worse, she was concerned she was not going to be able to walk one day. With her diagnosis in Oct2019 of invasive ductal malignant stage 2 breast cancer, she had radiation treatment and she is followed every 3 months by an oncologist. In the Fall of 2021, she noticed she had a mass at the incision site on her right breast. They did a mammogram and biopsy, and discovered it was fat necrosis and probably caused by radiation or an inflammatory process. She commented that thankfully the mass is benign, but it had been 2 years after radiation so she wondered if it was from the inflammatory process since her body was going through something very inflammatory. During her hospitalization for her left foot, a Nurse Practitioner who saw her thought it had something to due with an inflammatory response and on a news network she saw a Dr discussing problems with the Pfizer Covid Vaccine and studies were being done about the RNA and DNA. It would be a worry because it could cause autoimmune and inflammation. She  took this vaccine and things were getting worse for her. She stated she was reporting her side effects to Pfizer because the vaccine has changed for the worse and harmed her for the worse. She states she sees the doctors. She sees an Endocrinologist and she has always struggled with her blood sugar, and since all of this it has always been that much harder to control her blood sugar and it has been very high for quite some time. She states she is so sick and depressed and feels like she is constantly on edge and because of the adrenal glands enlarged, her doctor told her about cortisol and stress producing hormones were elevated so they did a saliva and urine test and because on some blood work it was showing cortisol levels were elevated, they did a series of tests in and out of the hospital to see if another condition but they were glad to report she didn't feel she had it. Caller states the elevated stress made her blood sugar levels difficult to control, she was Insulin Resistant to begin with.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202200418077 same patient/vaccine, different dose /event