Sex: F
Vaccine: VARZOS
Symptoms: Demyelinating polyneuropathy, Dyspnoea at rest, Electromyogram abnormal, Gait disturbance, Guillain-Barre syndrome
Clinical narrative: chronic inflammatory demyelinating polyneuropathy (CIDP); This spontaneous report as received from a 60 years old female nurse with arthritis, drug allergy to ciprofloxacin hydrochloride(CIPRO)(really bad nightmares), drug allergy to  azathioprine(IMURAN)(extreme nausea), allergies, drug allergy to penicillin(rash and facial swelling) and hot flashes refers to herself.  It was also reported as that the patient had no pertinent medical history.   On 05-MAY-2012(also reported as 08-MAY-2012) the patient was vaccinated with zoster vaccine live(ZOSTAVAX)(lot#672429/1606AA,expiration date 13-JAN-2013) 0.65 ml, subcutaneous in the right arm.    Concomitant therapies included levothyroxine sodium(manufacture unknown), ibuprofen, gabapentin and pseudoephedrine hydrochloride(SUDAFED).    On 12-MAY-2012, the patient began experienced "shortness of breath at rest, increased heart rate, labile blood pressure, and autonomic dysfunctions." On 25-MAY-2012, the patient had a lumbar puncture and unspecified labs done which resulted "negative." She reported that an unspecified physician diagnosed her with "anxiety" after her test results in regards to the symptoms that she was experiencing. She had three separate trips to a Hospital, "between May and June 2012" due to generalized weakness. On one occasion in "mid-June", she was admitted overnight to the hospital for diagnosis of Anxiety. On 09-JUL-2012, the patient was diagnosed with Guillain-barre syndrome after having an office visit with physician. An electromyography was done on 11-JUL-2012 which showed Severe demyelinating neuropathy. On 12-JUL-2012, the patient was again admitted to the Hospital. The patient reported she was given an unspecified treatment in the hospital for Guillain-barre syndrome but did not respond, so the hospital classified her condition as Chronic inflammatory demyelinating polyneuropathy (CIDP) . During her hospital stay, she reported that she "coded" twice. She reported that she was not discharged from the hospital until the "beginning of September 2012". She stated that she went back in a "couple of days later" because she needed IgG (immunoglobulin G). Since then, she reported that she receives IgG "every three weeks and now walks with a cane at times". The outcome of the event was reported as not recovered/not resolved.   The event Chronic inflammatory demyelinating polyneuropathy (CIDP) was considered to be disabling.  All telephone attempts to obtain follow-up information have been unsuccessful.  Follow-up information has been received on 31-MAR-2022, from a lawyer, regarding a case in litigation referring to a female patient (pt). In or around May 2012, the patient was inoculated with zoster vaccine live (ZOSTAVAX) for routine health maintenance and for its intended purpose: the prevention of shingles (herpes zoster). On an unspecified date, shortly after receiving zoster vaccine live (ZOSTAVAX) vaccine, the patient suffered polyneuropathy. As a direct and proximate result of zoster vaccine live (ZOSTAVAX), the patient's symptoms have resulted in physical limitations and seriousness of her condition. As a result of the zoster vaccine live (ZOSTAVAX), she sustained severe and permanent personal injuries. Further, as a tragic consequence, the patient suffered serious, progressive, permanent, and incurable injuries, as well as significant conscious pain and suffering, mental anguish, emotional distress, loss of enjoyment of life, physical impairment and injury. As a direct and proximate result, she suffered and incurred damages, including medical expenses; the loss of accumulations; and other economic and non-economic damages. The outcome of polyneuropathy was considered to be not recovered. The reporter considered polyneuropathy to be related to Zoster Vaccine Live (ZOSTAVAX).  Upon internal review, the event of polyneuropathy was determined to be medically significant and disabling.