Title: Transmissible spongiform encephalopathies : scrapie, BSE and related human disorders /
Authors: Chesebro, B. W.
Publisher: Springer-Verlag,
Year: 1991
Subjects: Scrapie.; Central nervous system Diseases.; Kuru.; Slow virus diseases.; Slow virus diseases in animals.; Bovine spongiform encephalopathy.; Creutzfeldt-Jakob disease.; Encephalopathy, Bovine Spongiform; Scrapie; Prion diseases.; Scrapie Etiology.; Bovine spongiform encephalopathy Etiology.; Alzheimer's disease Etiology.
Contents: The human spongiform encephalopathies: Kuru, Creutzfeldt-Jakob Disease, and the Gerstmann-Straussler-Scheinker Syndrome -- Bovine spongiform encephalopathy -- Purification of scrapie agents: how far have we come? -- The scrapie fibril protein and its cellular isoform -- Ultrastructural studies of prions -- In vitro expression and biosynthesis of prion protein -- Prion protein genes: evolutionary and functional aspects -- Scrapie strain variation and its implications -- Evidence for biological and structural diversity among scrapie strains -- Genetics of prion diversity and host susceptibility -- Natural transmission and genetic control of susceptibility of sheep to scrapie -- The scrapie agent in vitro.