Title: Molecular approaches to human polygenic disease.
Authors: Bock, Gregory.; Collins, Geralyn M.; Ciba Foundation.
Publisher: Wiley,
Year: 1987
Subjects: Genetic Linkage; Genetic Diseases, Inborn; Genetics; Genetic disorders Congresses.; Medical genetics Congresses; Molecular genetics Congresses.
Contents: Human gene mapping / Robert Williamson -- Genetics of coronary heart disease and its risk factors / Kåre Berg -- The LDL receptor : oligonucleotide-directed mutagenesis of the cytoplasmic domain / C. Geoffrey Davis -- Apolipoproteins, quantitative lipoprotein traits and multifactorial hyperlipidaemia / Gerd Utermann -- Structure and evolution of human apolipoprotein genes : identification of regulatory elements of the human apolipoprotein E gene / John M. Taylor, Steve Lauer, Nabil Elshourbagy, Catherine Reardon, Ellen Taxman, David Walker, David Chang, Young-Ki Paik -- Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes / Charles F. Sing, Eric A. Boerwinkle -- Use of DNA polymorphisms of the apolipoprotein genes to study the role of genetic variation in the determination of serum lipid levels / Steve E. Humphries, Philippa J. Talmud, Anna M. Kessling -- Hypertension and the genetics of red cell membrane abnormalities / Arno G. Motulsky, Wylie Burke, Paul R. Billings, Richard H. Ward -- The molecular genetics of diabetes mellitus / G.I. Bell, K. Xiang, S. Horita, N. Sanz, J.H. Karam -- Searching for major genes for psychiatric disorders / Kenneth K. Kidd -- The molecular genetics of HLA-related disorders / J.I. Bell -- The human genome sequence and the analysis of multifactorial traits / Walter F. Bodmer -- Gene therapy : efforts at developing large animal models for autologous bone marrow transplant and gene transfer with retroviral vectors / Martin A. Eglitis, Philip W. Kantoff, Jeanne R. McLachlin, Al Gillio, Alan W. Flake, Claudio Bordignon, Robert C. Moen, Evelyn M. Karson, James A. Zwiebel, Donald B. Kohn, Eli Gilboa, R. Michael Blaese, Michael R. Harrison, Esmail D. Zanjani, Richard O'Reilly, W. French Anderson -- Implications of genetic research for control measures / Geoffrey Rose.