Title: Anticoagulants, antiplatelets, and thrombolytics /
Authors: Mousa, Shaker A.
Publisher: Humana Press,
Year: 2004
Subjects: Anticoagulants (Medicine); Blood platelets.; Thrombolytic therapy.; Fibrinolytic agents.; Thrombolytic Therapy methods; Anticoagulants therapeutic use; Fibrinolytic Agents therapeutic use; Heparin therapeutic use; Platelet Aggregation Inhibitors therapeutic use; Thrombocytopenia drug therapy
Abstract: Provides an update on various clinically relevant in vitro and in vivo models of thrombosis and haemostasis. The editor goes further to provide highlights of the novel usage of low molecular weight heparins, newer application of GPIIb/IIIa antagonists, asprin and clopidogrel, and expanded usage of polytherapeutic approaches. The book provided a contemporary look at progress achieved during the past decade In the development of newer drugs to treat thrombotic and cardiovascular diseases. This reference explains the process of establishing these newer treatments as well as reviewing all the aspects and defining the clinically relevant models for the discovery of newer generation antithrombotics. The chapters embody a manual for hematologists, pharmacologists, vascular, and cardiovascular specialists, to use in their daily practice.
Contents: Highlights of latest advances in antithrombotics / S.A. Mousa -- Antiplatelet, anticoagulant, and thrombolytic drug interactions / O. Iqbal and S.A. Mousa -- Evaluation of platelet antagonists in in vitro flow models of thrombosis / O.J. McCarty ... [et al.] -- Heparin and low molecular weight heparin in thrombosis, cancer, and inflammatory diseases / S.A. Mousa -- Are low molecular weight heparins the same? / S.A. Mousa -- Antithrombotic drugs for the treatment of heparin-induced thrombocytopenia / W.P. Jeske and J.M. Walenga -- Laboratory methods for heparin-induced thrombocytopenia / M. Prechel, W.P. Jeske and J.M. Walenga -- Factor Xa inhibitors / J.M. Walenga ... [et al.] -- Tissue factor/VIIa in thrombosis and cancer / S.A. Mousa -- Tissue factor pathway inhibitor in thrombosis and beyond / S.A. Mousa ... [et al.] -- Cell adhesion molecules: potential therapeutic and diagnostic implications / S.A. Mousa -- Development and applications of animal models of thrombosis / R.J. Shebuski ... [et al.] -- A survey of venous thrombosis models / W.P. Jeske ... [et al.] -- Arixtra (fondaparinux sodium) / S.A. Mousa -- Oral thrombin inhibitor ximelagatran / S.A. Mousa -- Pharmacogenomics and coagulation disorders / O. Iqbal -- Guidelines for diagnosis and treatment of deep venous thrombosis and pulmonary embolism / H. Abdel-Razeq ... [et al.].