Title: Asthma, basic mechanisms and clinical management /
Authors: Barnes, Peter J., 1946-; Rodger, Ian W.; Thomson, Neil C.; Rodger, I. W.
Publisher: Academic Press,
Year: 1998
Subjects: Asthma drug therapy; Asthma etiology; Asthma physiopathology; Asthma
Abstract: Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy. The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field. Key Features * Comprehensive coverage of both basic science and clinical aspects of asthma * Extensively referenced throughout.
Contents: M. Sears, Epidemiology. -- B. Meijer, E. Bleecker, and D. Postma, Genetics of Asthma. -- P. Jeffrey, Airway Pathology in Asthma. -- N. Pride, Physiology. -- L.J. Janssen, E.E. Daniel, and I.W. Rodger, Airway Smooth Muscle Cells. -- F.L. Pearce, Mast Cells and Basophils. -- C.M. Hawrylowicz and T.H. Lee, Monocytes, Macrophages and Dendritic Cells. -- P. Venge, The Eosinophil. -- G. Anderson, Lymphocytes. -- J.L. Devalia, M.M. Abdelaziz, and R.J. Davies, Epithelial Cells. -- Y.C. Liu, A.M. Khawaja, and D.F. Rogers, Pathophysiology of Airway Mucus Secretion in Asthma. -- D.J. Godden, Tracheobronchial Circulation. -- A. Wardlaw, Adhesion Molecules. -- C. Persson, Microvascular-EpithelialExudation of Plasma. -- P.M. OByrne, Prostaglandins and Thromboxane. -- J. Drazen, Cysteinyl Leukotrienes. -- D. Proud, Kinins. -- K.F. Chung, Chemokines. -- D.S. Robinson, Lymphokines. -- F.K. Chung and P.J. Barnes, Other Mediators of Asthma. -- P.J. Barnes, Nitric Oxide. --^