Title: HIV and the pathogenesis of AIDS /
Authors: Levy, Jay A.
Publisher: ASM Press,
Year: 2007
Subjects: HIV (Viruses); HIV infections Pathogenesis.; HIV Infections etiology; HIV Infections physiopathology; Acquired Immunodeficiency Syndrome etiology; Acquired Immunodeficiency Syndrome physiopathology; HIV
Abstract: Overview of the field of HIV pathogenesis, presenting the aspects of HIV infection and control.
Contents: Discovery, structure, heterogeneity, and origins of HIV -- Features of HIV transmission -- Steps involved in HIV: cell interaction and virus entry -- Acute HIV infection and cells susceptible to HIV infection -- Intracellular control of HIV replication -- Cytopathic properties of HIV -- Viral proteins determining biologic features of HIV -- Effect of HIV on various tissues and organ systems in the host -- Innate immune responses in HIV infection -- Humoral immune responses to HIV infection -- T-lymphocyte immune responses in HIV infection -- HIV infection and development of cancer -- Overall features of HIV pathogenesis: prognosis for long-term survival -- Antiviral therapies -- Vaccine development.