Title: Targets for cancer chemotherapy : transcription factors and other nuclear proteins /
Authors: La Thangue, Nicholas B.; Bandara, Lan R.; Bandara, Lasantha R.
Publisher: Humana Press,
Year: 2002
Subjects: Oncogenes.; Tumor proteins.; Transcription factors; Cancer Chemotherapy; Neoplasms drug therapy; Transcription Factors; Receptors, Cytoplasmic and Nuclear; Oncogene Proteins; Genes, Tumor Suppressor physiology; Drug Design
Contents: 1. Cancer Chemotherapy Based on E2F and the Retinoblastoma Pathway / William G. Kaelin, Jr. -- 2. Myc Oncoproteins as Targets for Therapeutic Intervention in Tumorigenesis / Bernd Berwanger and Martin Eilers -- 3. The AP-1 Family of Transcription Factors: Structure, Regulation, and Functional Analysis in Mice / Marina Schorpp-Kistner, Peter Herrlich and Peter Angel -- 4. Hypoxia-Induced Factor-1 as a Target for Anticancer Therapy / Shoumo Bhattacharya -- 5. Nuclear [beta]-Catenin Signaling as a Target for Anticancer Drug Development / Eun Joo Chung, Paolo Bonvini and Ho Jung Oh / [et al.] -- 6. Histone Acetyltrasferases as Potential Targets for Cancer Therapies / Stuart Thomson and Louis C. Mahadevan -- 7. Histone Deacetylases / Manfred Jung -- 8. Cyclin-Dependent Kinases and Their Small-Molecule Inhibitors in Cancer Therapy / R. Nagaraja Rao and Bharvin K. R. Patel -- 9. Mitogen-Activated Protein Kinase Cascades as Therapeutic Targets in Cancer / Antonio Chiloeches and Richard Marais -- 10. MDM2 and ARF / Andrea Klotzbucher and Michael H. G. Kubbutat -- 11. The Breast Cancer Susceptibility Genes BRCA1 and BRCA2 / Anastasia Gabriel and Alan Ashworth -- 12. Human Papillomavirus Targets for Therapeutic Intervention / David Pim, Miranda Thomas and Lawrence Banks -- 13. Apoptin as an Anticancer Therapy / Mathieu H. M. Noteborn -- 14. E2F and Cancer Chemotherapy / Debabrata Banerjee and Joseph R. Bertino -- 15. Hypoxic Signaling Pathways as Targets for Anticancer Therapy / Heidi M. Sowter and Adrian L. Harris -- 16. Androgen Receptor and Estrogen Receptors / H. M. Oosterkamp and R. Bernards.