Title: Multiple myeloma : methods and protocols /
Authors: Brown, Ross D.; Ho, P. Joy.
Publisher: Humana Press,
Year: 2005
Subjects: Multiple Myeloma genetics; Multiple Myeloma immunology; Multiple myeloma Molecular aspects Laboratory manuals.; Multiple Myeloma immunology Laboratory Manuals.; Multiple Myeloma genetics Laboratory Manuals.
Abstract: A comprehensive collection of classic and innovative methodologies used in many laboratories for the investigation of multiple myeloma. These readily reproducible techniques range from the standard Plasma Cell Labeling Index methodology to a final chapter on making sense of microarrays, and include the full spectrum of cytogenetic and molecular diagnostic methods. These proven techniques are ideal for studying the pathogenesis of multiple myeloma and identifying new therapeutic targets.
Contents: Multiple myeloma : challenges and opportunities / Douglas Joshua, Ross Brown, and P. Joy Ho -- Immunophenotyping of plasma cells in multiple myeloma / Gema Mateo Manzanera, Jesus F. San Miguel, and Alberto Orfao de Matos -- The plasma cell labeling index / Philip Griepp and Shaji Kumar -- Conventional cytogenetics in myeloma / Lynda Campbell -- Multicolour spectral karyotyping in multiple myeloma / Jeffrey Sawyer -- Detection of chromosome 13 deletions by fish / Scott van Wier and Rafael Fonseca -- Comparative genomic hybridization for analysis of DNA copy number changes in multiple myeloma / Pulivarthi H. Rao.