Title: NMR in drug design /
Authors: Craik, David James.
Publisher: CRC Press,
Year: 1996
Subjects: Magnetic Resonance Spectroscopy; Drug Design; Drugs Design.; Nuclear magnetic resonance spectroscopy.
Contents: Drug design and discovery : where next? / Peter R. Andrews -- The role of NMR in drug design and development / David J. Craik -- Studies of drug-receptor interactions by NMR : theory and applications / J.T. Gerig -- Protein structure determination using NMR spectroscopy / Glenn F. King and Joel P. Mackay -- Conformational analysis of drug molecules / Jerzy W. Jaroszewski -- Conformational analysis of peptides : applications to drug design / Horst Kessler, Robert K. Konat, and Wolfgang Schmitt -- Protein-ligand interactions : examples in drug design / Robert M. Cooke -- NMR studies of ligand binding to dihydrofolate reductase and their application in drug design / J. Feeney -- Studies of drug-calmodulin using isotopically labelled protein / David G. Reid, Andrew J. Edwards, and Patricia J. Sweeney -- Flexibility and function in the HIV-1 protease / Linda K. Nicholson, Chong-Hwan Chang, and C. Nicholas Hodge -- DNA as a target for drug action : complexes of intercalating antibiotics / Mark S. Searle -- Drug binding to the minor groove of DNA / David J. Craik, Spiro Pavlopoulos, and Geoffrey Wickham.