Title: Inflammatory bowel disease : genetics, barrier function, immunologic mechanisms, and microbial pathways /
Authors: Domschke, Wolfram.; New York Academy of Sciences.
Publisher: Published by Blackwell Pub. on behalf of the New York Academy of Sciences,
Year: 2006
Subjects: Inflammatory Bowel Diseases microbiology; Inflammatory Bowel Diseases immunology; Inflammatory Bowel Diseases genetics; Inflammatory bowel diseases Congresses; Inflammatory Bowel Diseases genetics Congresses.; Inflammatory Bowel Diseases immunology Congresses.; Inflammatory Bowel Diseases microbiology Congresses.
Contents: Current limitations of IBD treatment: Where do we go from here? -- Genetics -- CARD15/NOD2 mutations in Crohn's disease -- Innate immune sensing of microbes by Nod proteins -- Immunologic mechanisms -- Animal models of inflammatory bowel disease: lessons from enteric infections -- Molecular approaches to the role of the microbiota in inflammatory bowel disease -- CCR6 and CCL20: partners in intestinal immunity and lymphorganogenesis -- Apoptosis as a therapeutic tool in IBD? -- Intestinal microvasculature as a therapeutic target in inflammatory bowel disease -- Novel signal transduction pathways: analysis of STAT-3 and Rac-1 signaling in inflammatory bowel disease -- NF-kB signaling: pros and cons of altering NF-kB as a therapeutic approach -- Role of the melanocortin system in inflammation -- Immunology of Crohn's disease -- Role of CEACAM1 as a regulator of T cells -- Therapeutic drug delivery by genetically modified Lactococcus lactis --^