Title: Biological response modifiers in human oncology and immunology /
Authors: Klein, Thomas W.
Publisher: Plenum Press,
Year: 1983
Subjects: Neoplasms immunology; Neoplasms therapy; Immunotherapy; Dose-Response Relationship, Immunologic; Acquired Immunodeficiency Syndrome immunology; Cancer Immunological aspects Congresses; Immunotherapy Congresses.; Biological response modifiers Congresses.
Abstract: The topic of biological response modifiers has attracted the attention of many biomedical investigators, including immunologists, oncologists, pharmacologists, microbiologists, and biochemists, as well as clinical practitioners of medicine. This has occurred mainly because of the realization that the complex system of cellular and humoral interactions culminating in a productive immune response is under exquisite regulatory control for normal immune responses and that loss of control may markedly influence the capability of a host to respond in a productive manner to the numerous immunologic "insults" encountered in the environment. Furthermore, biological response modification is considered by many to be a natural offshoot of the relatively new application of "immunotherapy" to cancer.^