Title: Principles of clinical pharmacology /
Authors: Atkinson, Arthur J.,; Atkinson, Arthur J.,
Publisher: Academic Press,
Year: 2007
Subjects: Clinical pharmacology; Pharmacology, Clinical; Pharmacologie clinique.; Farmacologie.
Contents: Introduction to clinical pharmacology / Arthur J. Atkinson, Jr. -- Pharmacokinetics -- Clinical pharmacokinetics ; Compartmental analysis of drug distribution ; Drug absorption and bioavailability / Arthur J. Atkinson, Jr. -- Effects of renal disease on pharmacokinetics / Arthur J. Atkinson, Jr. and Marcus M. Reidenberg -- Pharmacokinetics in patients requiring renal replacement therapy / Arthur J. Atkinson, Jr. and Gregory M. Susla -- Effect of liver disease on pharmacokinetics / Gregory M. Susla and Arthur J. Atkinson, Jr. -- Noncompartmental versus compartmental approaches to pharmacokinetic analysis / David M. Foster -- Distributed models of drug kinetics / Paul F. Morrison -- Population pharmacokinetics / Raymond Miller -- Drug metabolism and transport -- Pathways of drug metabolism ; Methods of analysis of drugs and drug metabolites / Sanford P. Markey -- Clinical pharmocogenetics / David A. Flockhart and Leif Bertilsson -- Equilibrative and concentrative transport mechanisms / Peter C. Preusch -- Drug interactions / Sarah Robertson and Scott Penzak -- Biochemical mechanism of drug toxicity / Arthur J. Atkinson, Jr. and Sanford P. Markey -- Assessment of drug effects -- Physiological and laboratory markers of drug effect / Arthur J. Atkinson, Jr. and Paul Rolan -- Dose-effect and concentration-effect analysis / Elizabeth S. Lowe and Frank M. Balis -- Time course of drug response / Nicholas H.G. Holford and Arthur J. Atkinson, Jr. -- Disease progress models / Nicholas H.G. Holford, Diane R. Mould, and Carl C. Peck -- Optimizing and evaluating patient therapy -- Pharmacological differences between men and women / Maylee Chen, Joseph S. Bertino, Jr., Mary J. Berg, and Anne N. Nafziger -- Drug therapy in pregnant and nursing women / Catherine S. Stika and Marilynn C. Frederiksen -- Drug therapy in neonates and pediatric patients / Elizabeth Fox and Frank M. Balis