premise: Is genetically modifying DNA the same as what breeders and horiculturalists have been doing for centuries?
hypothesis: Genetically modifying an organism is completely different. The DNA of an organism has a protection against being modified by another invading organism, so the introduction of another specie's genetic material must be forced and is a crude unpredictable process at the current time. There is no prediction of what such disruptions will cause in future generations of the organism that reproduces with compromised DNA.