premise: "I can't begin to tell you how phenomenally helpful it would be if we had some marker, whether it was measurable on an MRI or whatever, because if we knew which kids were truly going to be in the 20 percent, <hypo>," Spack says.
hypothesis: <hypo> should be "then I think everybody would say then those kids should be raised in the affirmed gender and the gender consistent with their brain wiring"