UTC An excellent reason to oppose You might like to reconsider though given the content of the Professor Mean reference and any number of others that could be shown See below NoeticaTea Support I have now researched this closely See a section below on this talkpage and see recent changes to the article I am satisfied that the rule is applied in statistical inference generally even though it is especially well suited to inferences in medical and pharmaceutical research Some recent sources found in Google books Published in 2006Published in 2011 See also my added note in the article There is a distinct meaning for the term in statistics but it does not yet have its own WP article Until it does this article deserves the title Rule of three statistics NoeticaTea 02 40 1 January 2013