Useful documentation for this comparison can be found on p 1 of Gabriel Danovitch Handbook of Kidney Transplantation Philadelphia Lippincott 2001 where he states that the most efficient hemodialysis regimens currently provide only 10 tp 12 of the small solute removal achieved by two normally functioning kidneys This comment should be updated however by reference to data from the new programs of short and long daily home hemodialysis performed six days or nights a week which improve solute clearance although still fall far short of achieving what normal kidneys can do User JP Marat