Interesting 208 to add to your list Non Steroidal Anti inflammatories NSAIDS Data from metanalysis of gastrointestinal complicationsrelated to use of nonsteroidal anti inflammatory drugs Gabrie et al 1991 Serious GI event 3 2 1000 subjects age 65 39 1000 subjects age 65 1 1000 subjects all ages NaprosynData from Physicians desk reference selected complications based on reports in clinical trials in the literature adn on voluntary reports since marketing GI bleeding and or perforation 1 100 Renal failure 1 100 Congestive heart failure 1 100