Quick question Could someone please explain to me why aspirin is used in the stack in place of other NSAIDS COX inhibitors such as Ibuprofen and acetominophen I realize that aspirin is an irreversible inhibitor of COX and would mostly like work longer because more enzymes would have to be made to reverse its effects but by the logic presented in the article couldn t other reversible inhibitors contribute the same effect Would a regimen of aspiring staggered out with tylenol and ibuprofen increase the thermogenic effect It is nearly impossible to find good information online because everyone has their own anecdotal evidence with NO FACTS to ever back it up wamerocity