Making symptoms worse or adding side effects I have schizophrenia and have taken Risperdal and now Zyprexa This article describes the dramatic increase in synaptic dopamine bought about by release of endogenous dopamine by electrical stimulation and antipsychotic treatment and the experiment was successfully repeated a number of times and established Similar levels of dopamine in the mM range are achieved with amphetamine and can lead to disturbed sexuality With such high levels of dopamine serotonin usually ramps down could this lower serotonin cause depression and guilt Steve