PNAS It would have been more helpful if you had read WP MEDRS fully before leaving a message on my talkpage PNAS is indeed a high quality journal and heavily cited in the scientific community but that doesn t make it an ideal source from the perspective of a general purpose encyclopedia Clearly the study in question does a lot in explaining that the effects of thyroid hormones may actually be mediated by autonomous nervous system activity But it is together with PMID 18182466 a very early study into this phenomenon It would need to be reproduced perhaps in different models before becoming suitable for inclusion into a general encyclopedia In such a case it would be much preferable to cite a secondary source e g a review or a textbook chapter that puts this interesting study in a wider perspective I hope this clarifies matters Please have a look at WP MEDRS again and let me know if there are any outstanding issues