intraorally , it presents as a soft - tissue swelling of the maxillary anterior mucolabial fold , lateral to midline leading to obliteration of the nasolabial fold . it is submucosal and extraosseous , spreads in the labial sulcus and expands all the soft tissues outwards . extraorally , it appears as a swelling between the upper lip and nasal aperture causing elevation of nasal ala . the terms nasolabial and nasoalveolar cysts have been used synonymously , as these are similar cysts with the only difference that the former is a lesion located entirely within the soft tissues and the latter causes maxillary alveolar bone erosion . a 69-year - old female reported to the dental college with a chief complaint of an extraoral swelling on the right side of her upper lip and elevation of the alar base [ figure 1a ] since 7 - 8 months . history of present illness revealed that the swelling had increased in size since its initiation but was not associated with any pain , drainage through oral / nasal cavity or difficulty in breathing through nasal obstruction . furthermore , there was no history of dacryocystitis / watery eyes but there was a swelling intraorally corresponding to this extraoral swelling which was obliterating the labial vestibule on that side . intraoral examination revealed bilateral smooth , soft , fluctuant masses lateral to the central incisor teeth in the maxillary labial vestibule . the right - sided mass was well - defined [ figure 1b ] and measured approximately 2  3 cm and left - sided mass measured 1.5  1.5 cm when palpated bimanually . aspiration biopsy from right - sided mass revealed straw - colored fluid [ figure 1c ] . ( a ) clinical picture showing extraoral swelling and elevation of alar base on the right side . ( b ) clinical picture showing intraoral swelling in the labial vestibule on the right side . ( c ) straw - colored fluid on aspiration from the right - sided cyst occlusal radiograph [ figure 2a ] showed a large scooped - out radiolucent area with cupping surrounding upper left central incisor ( ul1 ) in the middle and coronal thirds of its root , but not in the periapical area . the cysts were enucleated [ figure 2b and c ] using intraoral approach under local anesthesia and adrenaline ( 1:80,000 ) . a full - thickness incision was reflected along the crest of maxillary alveolar ridge in the canine to canine region and blunt dissection by periosteal elevator exposed two smooth , well - circumscribed cystic swellings just below the nasal floor . there had been scooping of the anterior maxilla on the left side due to expansion of the cyst . in contrast , morphology of alveolar bone on right side was not affected . in the same appointment , extractions of hopeless teeth were also done and the wound was closed with loop sutures using 3 - 0 non - absorbable black mersilk after debridement and irrigation with normal saline . ( c ) enucleation of left cyst histopathology of the right - sided cyst revealed a cystic cavity lined by variable thickness of epithelium predominantly made up of many layered stratified squamous cells along with a few mucosal cells [ figure 3 ] . at few places , stratified squamous and pseudostratified columnar epithelia with many cilia and goblet cells were also evident [ figure 4a and b ] . left - sided cyst specimen showed two or more layered stratified squamous lining epithelium with thin capsule [ figure 5 ] . photomicrograph of a section of right cyst showing epithelial lining predominantly made of many layered stratified squamous cells with few mucosal cells ( h&e stain , 100 ) ( a ) photomicrograph of right cyst : stratified squamous epithelium with mucous cells and cilia ( h&e stain , 400 ) . ( b ) photomicrograph of right cyst : pseudostratified ciliated columnar epithelium with goblet cells ( h&e stain , 400 ) photomicrograph of left cyst showing cystic cavity lined by stratified squamous non - keratinized epithelium with thin capsule ( h&e stain , 40 ) patients seek medical assistance when the cyst becomes infected or cause a cosmetic defect . in the present case , intraoral swellings were present in the labial vestibule on both sides , lateral to the maxillary central incisors , which is the most common symptom associated with this cyst . as the nasolabial cysts arise in soft tissues , in most cases there are no radiographic changes . occasionally , pressure resorption of the underlying bone may occur , in that case , it is known as nasoalveolar cyst , where the cyst being external to the alveolar bone , produces  cupping  of the underlying cortical plate . in the present report , erosion of bone in a  cupping  fashion around ul1 was observed as a sequel of pressure from the cyst . routine intraoral radiographs are not diagnostic for nasoalveolar cysts but assist in excluding other odontogenic or non - odontogenic cysts . periapical inflammatory lesions can be excluded by vitality testing of the associated teeth and the absence of radiolucency in the periapical region on intraoral radiographs . globulomaxillary and nasopalatine duct cysts can easily be mistaken as nasolabial cysts ; however , both of these are intraosseous lesions . in the present case , , the rarefaction was observed in the middle and coronal third of the root of ul1 . however , cohen and hertzanu have reported a case of nasolabial cyst with a high growth potential that resulted in the erosion of maxillary alveolus , invaded supporting structures in the region of incisors and caused displacement of these teeth . in the present case also , there were signs of displacement of adjacent teeth . distolabial migration of the crowns of upper central incisors was primarily due to loss of periodontal support caused by periodontitis in addition to pressure from the cyst . 10.6% of nasolabial cysts are bilateral , this finding suggests that these cysts are developmental in origin . etiopathogenesis of this cyst involves two theories suggesting that it arises : 
 as a fissural cyst which develops from embryonic nasal epithelium entrapped between the merging maxillary processes and the medial and lateral nasal processesas a developmental cyst arising from the remnants of the embryonic nasolacrimal ducts , due to histological similarities to the latter . furthermore , this cyst is in the area of the naso - optic furrow and proliferation of the nasolacrimal duct has been seen at this site . although this theory may need some revision , due to the finding of apocrine secretion along the surface of the nasolabial cyst , it seems to be the most accepted one at this stage . the fact that high percentage of linings demonstrate pseudostratified columnar epithelium , often with cilia or numerous goblet cells , is compatible with origin from primitive ductal or glandular structures . so , the most likely origin is from the nasolacrimal duct . in case presented here , the cystic lining was predominantly stratified squamous type , although few areas showed pseudostratified ciliated columnar epithelium . su et al . , in their scanning electron microscopic examination revealed that cilia observed in the light microscope were in fact numerous short globular or irregular microvilli which probably resulted from lack of stimulation by air . as a fissural cyst which develops from embryonic nasal epithelium entrapped between the merging maxillary processes and the medial and lateral nasal processes as a developmental cyst arising from the remnants of the embryonic nasolacrimal ducts , due to histological similarities to the latter . furthermore , this cyst is in the area of the naso - optic furrow and proliferation of the nasolacrimal duct has been seen at this site . although this theory may need some revision , due to the finding of apocrine secretion along the surface of the nasolabial cyst , it seems to be the most accepted one at this stage . the fact that high percentage of linings demonstrate pseudostratified columnar epithelium , often with cilia or numerous goblet cells , is compatible with origin from primitive ductal or glandular structures . so , the most likely origin is from the nasolacrimal duct . in case presented here , the cystic lining was predominantly stratified squamous type , although few areas showed pseudostratified ciliated columnar epithelium . , in their scanning electron microscopic examination revealed that cilia observed in the light microscope were in fact numerous short globular or irregular microvilli which probably resulted from lack of stimulation by air . in the present case , bimanual palpation ( best method of diagnosing this cyst by placing one finger in the labial sulcus and the other on the nasal floor ) revealed soft , fluctuant masses bilaterally . dimension of the cyst in the soft tissues of the labial sulcus was more ( 2  3 cm ) on the right side which also produced an extraoral swelling because this cyst was exclusively an extraosseous one . in contrast , the left - sided cyst measured relatively less ( 1.5  1.5 cm ) in the soft tissues with no corresponding extraoral swelling because the cyst was occupying space between the vestibular sulcus and alveolar bone as was evident on surgical exploration . the preferred method of treatment of this cyst is surgical excision by intraoral sub - labial approach , although care must be exercised to prevent perforation and collapse of the lesion . the surgical outcome of this method is generally successful ; however , complications associated with the procedure include facial swelling , gingival numbness , decreased sensation of the teeth , and wound infection . an alternative transnasal approach has been suggested that allows endoscopic marsupialization of the cystic cavity . in the present case , full thickness incision was given on the crest of the ridge instead of sub - labial incision ( and a mucoperiosteal flap was reflected with a periosteal elevator to expose the cysts ) because the surgical procedure was inclusive of extractions of adjacent mutilated teeth . so , in the presented case ; clinical , radiographic and histological features of the lesions were suggestive of nasolabial cyst on the right side and nasoalveolar cyst ( residing on the alveolar surface ) on the left side , which were successfully enucleated by a modification of intraoral sublingual surgical approach . in 1-year
nasolabial cysts are painless , submucosal , non - odontogenic jaw cysts presenting as soft tissue swellings in the maxillary anterior mucolabial fold lateral to midline , leading to elevation of nasal ala . 
 present case documents bilateral nasolabial cysts in a 69-year - old asian female patient . in the present case , extraoral 
 swelling of maxillary lip and elevation of nasal ala was observed on right side of the face . 
 intraorally , soft and fluctuant bilateral cysts were observed . 
 straw - colored fluid was aspirated from the right cyst . 
 radiographically , erosion of bone in a  cupping 
 fashion was observed in the region of left cyst . 
 the cysts were enucleated using intraoral approach . 
 histopathology of the right - sided cyst revealed a cystic cavity lined by stratified squamous cells along with a few mucosal cells . at few places , stratified squamous and pseudostratified columnar epithelia with many cilia and goblet cells were also evident . 
 capsule was loosely arranged with fibrous tissue and chronic inflammatory infiltrate . 
 left - sided cystic specimen showed two or more layered stratified squamous lining epithelium with thin capsule . 
 diagnosis of bilateral nasolabial / nasoalveolar cysts was confirmed .