epidermoid and dermoid cysts are benign lesions developing from abnormal epithelial components of ectodermal tissue formed during the fetal period , or implanted epithelium arising after trauma or surgery . these lesions , which can be seen anywhere in the body , occur in the head and neck area in approximately 7% of cases . those in the oral cavity are mostly in the floor of the mouth ( in the sublingual , submental or submandibular areas ) and in various other localizations including the labial , lingual or buccal mucosa . their incidence in the oral cavity makes up for 1.6% of the total occurrences and they constitute less than 0.01% of all the cystic lesions of the oral cavity . these cysts are termed  epidermoid  if they are enclosed in epithelium only , if they comprise skin appendages and  teratoid  if they include other tissues like muscle , cartilage or bone . surgical excision is sufficient for cure . even though reports of epidermoid cysts in the head and neck , especially those in the floor of the mouth , soft palate , lips , or the lingual and buccal epithelium can be found in the literature , but there is no report of an intratonsillar epidermoid cyst . we intend to report the case of a patient who underwent tonsillectomy for diagnostic purposes because of an epidermoid cyst arising from the tonsil and confirmed by histology . a 42-year - old female came to our clinic for sore throat and difficulty in swallowing . ent examination showed marked hypertrophy of the right tonsil in comparison with the contralateral one , and a smooth - surfaced mass near the upper pole of the tonsil [ figure 1 ] . a magnetic resonance imaging ( mri ) examination was performed , which evidenced a protrusion of the clearly hypertrophic tonsil into the nasopharynx [ figure 2 ] . a right tonsillectomy was performed for diagnostic purposes after having obtained the patient 's informed consent . it was interesting to note that these cavities contained keratin in a lamellar arrangement and their epithelium was of a squamous character [ figure 3 ] . the patient was discharged on the first post - operative day in excellent condition ; her follow - up , reaching 10 months , was entirely uneventful . view of the asymmetrical hypertrophy of the right tonsil with a mass arising in its upper pole view of the hypertrophic right palatine tonsil in t2-weighted mri cystic cavity within the tonsillar tissue lined with keratinized epithelium . dermoid cysts have been classified by meyer in 1955 as true dermoid cysts , epidermoid cysts and teratoid cysts . a true dermoid cyst is lined with keratinized epithelium and contains skin appendages that could be described as hair follicles or sebaceous glands . an epidermoid cyst , on the other hand , is lined with simple squamous epithelium and its wall does not contain fibrous structures or skin appendages . a teratoid cyst may contain tissues ranging from simple squamous epithelium to ciliated cylindrical respiratory epithelium ; its contents may be of ectodermal , mesodermal or endodermal in origin . a theory widely accepted today on the etiology of these lesions is their development from the epithelial remnants remaining isolated during the closure of the first and second branchial arches in the midline . another theory is the development of cysts from abnormal inclusion of cells during surgery or trauma . even though the fact that our patient was aged 42 years would seem to favor the latter mechanism , she presented no history of surgery or trauma . a study on 1495 cases by new and erich shows that their location is most frequently anal ( 44.5% ) and ovarian ( 42.1% ) . cases of cysts in the head and neck area are only 7% of the total body . in a study of 103 patients with diagnosis of epidermoid and dermoid cyst of the head and neck , 46.6% of these were orbital , 23.3% buccal and submental , 12.3% nasal , 10.7% cervical and 2.9% labial . various publications also report epidermoid cysts of the oral cavity in the soft palate , the uvula and the sublingual area . the male / female ratio of the patients with a diagnosis of epidermoid cyst is 3/13 and the age range of the large majority is 10 - 35 years . especially the latter fact leads to the thought that cyst formation could be stimulated by hormonal influence during puberty . the fact that our patient was a 42-year - old female would also support such an idea . the appearance of epidermoid cysts on mri is variable according to their fluid contents and protein density . often , though , they exhibit a low signal intensity with t1a sequences and a high signal intensity with t2a sequences . the mri performed in our patient showed a marked hypertrophy of the right tonsil , which was protruding into the nasopharynx . the fact that the appearance of the cyst in the mri examination was not cystic could be due to the high protein density of its contents . . it should be excised without opening because its contents could have an irritating effect on the surrounding fibrovascular tissue . a malignant evolution has only been seen in the teratoid type and was reported to have an incidence of 0.5% . a tonsillectomy was performed in our patient ; the cyst was excised within its capsule and the follow - up during 10 months was entirely uneventful . while the expansion of lymphoid follicles within the tonsil is the most frequent cause of their hypertrophy , asymmetric hypertrophy must lead to the suspicion of diseases like tonsillar tumor , atypical infection , granulomatous disease or tumors of the parapharyngeal area . in a series of 49 patients with asymmetrical tonsils with normal neck examination and normal overlying mucosa , only two ( 4.8% ) a diagnostic tonsillectomy is indicated as asymmetrical tonsillar hypertrophy carries a potential risk of neoplastic transformation . our patient also had an asymmetrical appearance of the tonsils . also , the mass covered by normal mucosa and arising from the upper pole was suspicious for the presence of tumor and the patient was subjected to diagnostic tonsillectomy . in conclusion , epidermoid cysts , a rare occurrence in the head and neck area , can also be found inside the palatine tonsils and cause asymmetrical hypertrophy .
epidermoid and dermoid cysts are benign , developmental lesions that can be encountered anywhere in the body . 
 our literature search did not result in a finding of any report of an epidermoid cyst located in the palatine tonsils . 
 this is a report of a 42-year - old female patient who underwent a tonsillectomy for diagnostic purposes because of an epidermoid cyst arising from the tonsil which was confirmed by histology .