different factors , especially genetic , effect individual attitude to regular physical activity in iranian traditional medicine . our aim was to conduct a comparative revision and evaluation of the effect of genetic factors on physical activity in classic medicine and iranian traditional medicine . in this study , we reviewed persian resources in the research center of traditional medicine at shiraz university of medical sciences . we also evaluated the texts on physical activity and genetics in pubmed and google scholar . the results of classical medicine revision showed the effect of especial genes on obesity and sedentary behavior . it is also derived from iranian traditional medicine resources that physical activity and sedentary behavior is affected by individual mizaj . the results showed that those with hot and cold mizaj have different genetic potentials in sedentary behavior and physical activity . such categorization would be helpful in identifying illnesses due to sedentary life in special groups of people .
background : different factors , especially genetic , effect individual attitude to regular physical activity in iranian traditional medicine . 
 it was believed that individual physical activity attitude is affected by mizaj too . 
 our aim was to conduct a comparative revision and evaluation of the effect of genetic factors on physical activity in classic medicine and iranian traditional medicine.methods:in this study , we reviewed persian resources in the research center of traditional medicine at shiraz university of medical sciences . 
 we also evaluated the texts on physical activity and genetics in pubmed and google scholar.results:the results of classical medicine revision showed the effect of especial genes on obesity and sedentary behavior . 
 it is also derived from iranian traditional medicine resources that physical activity and sedentary behavior is affected by individual mizaj.conclusion:the results showed that those with hot and cold mizaj have different genetic potentials in sedentary behavior and physical activity . 
 such categorization would be helpful in identifying illnesses due to sedentary life in special groups of people . 
 it would also allow designing dedicated treatment for each person .