Succinate-semialdehyde dehydrogenase, mitochondrial jẹ́ enzyme nínú ara àwọn ènìyàn tí ALDH5A1 gene máa ń kóòdù fún. Protein yìí wà ní ẹbí aldehyde dehydrogenase ti àwọn protein.  Gene yìí máa ń kóòdù fún  succinic semialdehyde dehydrogenase tí ó gbójú lé NAD+ ti mitochondria. Àìpóṣùwọ̀n enzyme yìí ni wọ́n ń pè ní  4-hydroxybutyricaciduria, tí kò wọ́pọ̀ nínú ìbíní tí kò ṣe rẹ́gí níbi ètò neurotransmitter tí à ń pè ní γ-aminobutyric acid (GABA). Lati ṣàtúnṣe àìṣe dédé yìí, omi ara ẹni tí ó ní ààrùn yìí máa ń kó GHB mọ́ra. Irú rè. méjì ọ̀tọ̀ọ̀tọ̀ ni a dámọ̀ fún gene yìí. "Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression". The Journal of Biological Chemistry 270 (1): 461–7. Jan 1995. doi:10.1074/jbc.270.1.461. PMID 7814412.  "Human succinic semialdehyde dehydrogenase. Molecular cloning and chromosomal localization". Advances in Experimental Medicine and Biology 414: 253–60. May 1997. doi:10.1007/978-1-4615-5871-2_29. PMID 9059628.  "Entrez Gene: ALDH5A1 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)".