Simeoni I wa Yerusalemu, mwana wa Kleofa, alikuwa Mkristo wa Kiyahudi aliyeongoza kanisa la Yerusalemu kama askofu (62 au 70–107) baada ya Yakobo Mdogo kuuawa. Tangu kale anaheshimiwa kama mtakatifu. Sikukuu yake inaadhimishwa tarehe 18 Februari au 27 Aprili. Eusebius wa Caesarea aliorodhesha maaskofu wa kanisa hilo. Kadiri ya Hegesippus, Simeoni alichaguliwa kwa kumshinda Thebutis, aliyetazamwa baadaye kama mzushi, akaongoza Wakristo wengi kuhamia Pella ng'ambo ya mto Yordani kabla ya vita vya ukombozi vya Wayahudi kuanza mwaka 66 na Hekalu la Yerusalemu kubomolewa mwaka 70. Kati ya miaka 107-117 alisulubiwa mjini Yerusalemu au mahali pa jirani chini ya kaisari Trajan. Watakatifu wa Agano la Kale Orodha ya Watakatifu Wakristo Orodha ya Watakatifu wa Afrika Orodha ya Watakatifu Wafransisko According to Eusebius, Saint Simeon of Jerusalem was selected as James' successor after the conquest of Jerusalem which took place immediately after the martyrdom of James (i.e. no earlier than 70 AD) which puts the account in conflict with that of Flavius Josephus who puts James death in 63 AD: Eddy, Paul R. and Boyd, Gregory A. (2007) The Jesus Legend: A Case for the Historical Reliability of the Synoptic Jesus Tradition.