Irene Ntale (alizaliwa 30 Januari 1989) ni mwimbaji, mtunzi wa nyimbo, na mpiga gitaa wa Uganda. Anaimba muziki reggae, na acoustic soul. Ntale alizaliwa na George William Ntale na mkewe. Alianza kuimba shuleni na katika kwaya ya kanisa ambapo pia alijifunza jinsi ya kupiga gita. She went to Kitante primary school, Kitante Hill School for O-level and Makerere High, now Migadde College, for A-level. She earned a Bachelor of Procurement and Logistics Management degree at Kyambogo University. Alianza kuimba shuleni na katika kwaya ya kanisa ambapo pia alijifunza jinsi ya kupiga gita. She used to perform at shows, singing other artists songs, until she went to Swangz Avenue. Ntale has had hit songs since, like "Gyobera", "Love letter" a collaboration with Bebe Cool, "Stay with me", "Nkubukinze" and "Olindaba". Mwanzoni mwa 2019, baada ya ziara nyingi huko Lagos, Nigeria, ilisemekana kuwa Ntale alikuwa akifanya mazungumzo na Universal Music Group Nigeria na mnamo 21 Agosti 2019, alisaini mkataba wa rekodi na Universal Music Group Nigeria, making her the first Ugandan artiste to be signed to the record label.