Nancy Isime onye amụrụ n'abalị iri na asaa n'ime ọnwa Disemba n'afọ 1991, bụ nwaafọ Naịjirịa n'eme ihe nkiri, onye nlereanya ejiji na onye mgbasa ozi. Amụrụ Isime na Edo Steeti . Ọ gụrụ akwụkwọ na mpaghara agụmakwụkwọ Social Work afọ abụọ na Mahadum Lagos . Na 2009, Isime meriri na Miss Valentine International beauty pageant,ma bụrụ onye nke abụọ na asọmpi Miss Telecoms Naịjirịa. Dị ka onye nlere anya ọ rụrụ ọrụ "House of Marie", "Ade Bakere", "Adebayo Jones", "Zizi Cardow", "Shakara Couture", "Konga Online" na ndị ọzọ . Isime ekwuola banyere ihe nlere anya ya si, "Na ọgwụchala inwe ike mbiahari ma jisie ike na ya ruo mgbe ịga enweta ihu ọma. Na Naijiria, ịme ngosi uwe adịghị ka ọ dị na mba ọdịda anyanwụ ebe ịga-enweta nnukwu ihuọma izuo ike, ,N'ebe a, ị nwere ike nweta nnukwu ihuọma gị ma laghachite azụ,yabụ na ọ dị oke mkpa na ị ga-enweta nnukwu ihuọma ma gaa n'ihu na-agbasi mbọ ike ma na-aga n'ihu ịlaghachite maka ọzọ.