Safinatu Buhari nee Yusuf (an haife ta a ranar 11 ga watan Disamba na shekara ta 1952 – 14 January 2006) malamar Najeriya ce kuma uwargidan shugaban kasar Najeriya daga shekara ta 1983 zuwa shekara ta 1985. Ita ce matar Muhammadu Buhari ta farko . An haifi anhaifi safinatu Buhari ne a ranar 11 ga Disamba 1952 ga Alhaji Yusufu Mani da Hajiya Hadizatu Mani a garin Jos, Jihar Filato. Ta kasance 'yar kabilar Fulani ta Arewacin Najeriya kuma ta fito daga karamar hukumar Mani a jihar Katsina . Ta yi makarantar firamare ta Tudun Wada . Iyalin ta sun koma jihar Legas ne a lokacin da kwamishinan al’amuran Legas na lokacin, Musa ‘Yar’adua ya nada mahaifinta a matsayin sakatarensa na sirri.. Ta shiga makarantar horas da malamai ta mata da ke Katsina, ta kuma sami shaidar kammala karatun digiri na biyu a shekarar 1971. Ta kware a ilimin Islamiyya, kuma an yi mata wasiƙu da Ingilishi da Larabci. safinatu Ta hadu da Muhammadu Buhari tana da shekaru 14 kuma sun yi aure a shekarar 1971 tana da shekaru 18. Sun haifi ‘ya’ya 5 wato;