Moyen-Chari na ɗaya daga cikin yankuna 23 na Chadi, wanda ke kudu da ƙasar. Babban birninta shine Sarh . Tsohon lardin mai wannan sunan ya fi girma kuma ya haɗa da Yankin Mandoul na zamanin yau. Yankin ya yi iyaka da yankin Guéra a arewa, yankin Salamat daga gabas, Jamhuriyar Afirka ta Tsakiya zuwa kudu, da Yankin Mandoul, Yankin Tandjilé da Chari-Baguirmi zuwa yamma. Yankin galibi shimfidar savannah ce, tare da kiyaye wasu yankuna a matsayin ɓangare na Manda National Park . Tafkin Iro, wanda ake zargi da ramuwar tasiri, yana cikin arewa maso gabas. Babban birnin Moyen-Chari shine Sarh, birni na uku mafi girma a cikin Chadi; sauran manyan matsugunan sun haɗa da Alako, Balimba, Baltoubaye, Bohobé, Boum Kebbir, Danamadji, Dindjebo, Djéké Djéké, Korbol, Koumogo, Kounou, Kyabé, Maro, Moussa Foyo, Ngondeye, Roro da Singako Kamar yadda yake a kidayar Chadi a shekara ta 2009, yawan yankin ya kasance mazauna 588,008. Manyan ƙungiyoyin yare sun haɗa da ƙungiyoyin larabawa kamar su Baggara, gaba daya suna magana da larabawan Chadi, Bagirmi, Boor, Bua, Ƙungiyoyin Gula kamar Gula Iro da Zan Gula, Kaba kungiyoyin