An haifi Muhammad Salisu Ibrahim a shekarar 1964 a garin Riruwai dake karamar hukumar Doguwa a jihar Kano. Ya halarci makarantar firamare ta Riruwai inda ya samu shaidar kammala karatunsa na firamare a shekarar 1975. Honorabul Salisu Ibrahim ya wuce makarantar gwamnati da ke Kazaure don samun shaidar kammala karatunsa na sakandare. Sha'awar karatunsa tun a makarantar firamare ta ba shi damar karanta Turanci tare da kware a fannin ilimin harsuna daga Jami'ar Maiduguri daga 1985 - 1989. Bayan hidimar kasa, Honorabul Salisu ya dauki aiki a kamfanin Triumph Publishing Company Limited a matsayin babban dan jarida. Ya yi aiki a matsayin Mai Kula da Ayyukan Kasuwanci. Kwararren dan jarida ya shiga aikin jaridar Daily Trust a matsayin Manajan Tallace-tallacen Pioneer Group tsakanin 2000 – 2006. Kafin shiga harkar siyasa, Honorabul Salisu ya kafa wani kamfani mai zaman kansa na Talla a Abuja mai suna The Print Communication a shekarar 2006. Kwarewar sa, kwarewar gudanar da aiki da kuma kwarewar sa da kuma yadda ya kamata. hangen nesa ya sanya shi a matsayin dan siyasa mai kudurin inganta matsayi da ci gaban al'umma.