Gasar cin Kofin Ƙasashen Afirka ta 2000 ita ce karo na 22 na Gasar Cin Kofin Afirka, ƙungiyar ƙwallon ƙafa ta Afirka (CAF). Ƙasashen Ghana da Najeriya ne suka dauki nauyinsa, waɗanda suka haɗa kai suka maye gurbin Zimbabwe a matsayin mai masaukin baƙi. Kamar dai a cikin shekara ta alif 1998, an raba filin ƙungiyoyi goma sha shida zuwa rukuni huɗu na huɗu. Kamaru ta lashe gasar, inda ta doke Najeriya da ci 4-3 a bugun fenariti. A matsayin masu nasara, sun cancanci shiga gasar cin kofin ƙwallon ƙafa ta FIFA na 2001 a matsayin wakilan Afirka. An yi tsammanin Zimbabwe za ta karɓi baƙuncin wannan bugun amma CAF ta yi watsi da shi a ranar 8 ga watan Fabrairu, shekara ta alif 1999, a Abidjan, Ivory Coast saboda rashin bin ka’idojin, CAF ta sanar da cewa za su karbi aikace-aikacen sabbin masu karɓar baƙuncin har zuwa 10 ga watan Maris, shekara ta alif 1999. Tayi: Misira Ghana Maroko Najeriya Masar, Ghana, Morocco da Najeriya, CAF ta yanke shawarar cewa za su bi ƙa'idojin karɓar baƙuncin gasar. Daga baya, Masar ta janye.