Nancy Handabile 'yar wasan kwaikwayo ce 'yar ƙasar Zambiya, 'yar jarida kuma mai shirya fina-finai. Handabile ta taka rawar ci gaba a cikin Wasannin Soyayya, inda ta lashe zaɓen nata don Ƙwararriyar Jaruma Mai Tallafawa a Kyautar Zaɓin Masu Kallon Magic na Afirka na 2014 . Ta ba da umarnin Tizibika, wani wasan kwaikwayo na gaskiya na izgili game da mata biyu da ke ƙoƙarin yin amfani da kafofin watsa labarun don samun suna . Har ila yau, ta ba da umarni da tauraro a cikin wasan kwaikwayon Zambezi Magic TV na Masarauso . A shekarar 2019 ta fito a fim ɗin Zimbabwe na Ubangijin Kush . A watan Disamba na 2018 an amince da Handabile a matsayin ɗaya daga cikin manyan masu shirya fina-finai mata takwas na Multi Choice a cikin Ƙungiyar Ci gaban Afirka ta Kudu (SADC). Ta yi amfani da wannan dama wajen yin kira da a kara yawan mata da za su shiga fagen daga cikin al’adar maza, da kuma shirya fina-finai don samun ƙarin tallafin kuɗi a ƙasar Zambiya. A watan Mayun 2019 ta sami lambar yabo ta mata ta Ankazi daga bankin Stanbic .