Hamza al-Mustapha (an haife shi a ranar 27 ga watan Yulin, shekarar alif 1960), babban hafsan sojan Najeriya ne kuma jami’in leƙen asiri wanda ya yi aiki a matsayin babban jami’in tsaro ga mai mulkin soja Janar Sani Abacha daga shekarar alif 1993 zuwa shekarar alif 1998. Hamza al-Mustapha an haife shi kuma yayi karatu a garin Nguru. Ya yi rajista a asirce a matsayin jami'in jami'a, a Makarantar Koyon Tsaro ta Najeriya kuma an ba shi izini a cikin Sojojin Najeriya a matsayin Laftana ta biyu . Daga watan Agusta shekarar ta alif 1985, zuwa watan Agusta shekara ta alif 1990, Al-Mustapha ya kasance Mataimakin-de-Camp (ADC) din Shugaban hafsan soji, Janar Sani Abacha. Duk shugaban sa da kuma shugaban kasa, Janar Ibrahim Babangida yana da cikakkiyar dogaro da iyawarsa, kuma sun damka masa wasu iko na daban, wadanda suka fi sauran jami'an da suka fi shi girma. Wannan ya kara nuna shi a matsayin mai karfin fada aji na soja. An horar da Al-Mustapha a matsayin jami’in leken asiri na soja.