Irene Chirwa Mambilima (Maris 31, 1952 - Yuni 20, 2021) ita ce Babbar Jojin Zambiya daga 2015 har zuwa mutuwarta a 2021. Ta kuma taba zama shugabar hukumar zabe ta kasar Zambiya sannan ta jagoranci zabukan 2006 da 2011 da kuma zaben shugaban kasa na watan Janairun 2015.Ta kasance cikin tawagar sa ido kan zabe da dama da suka hada da Liberia, Kenya, Mozambique, da Seychelles. Sauran ayyukanta na duniya sun haɗa da yin aiki a matsayin Alkalin Kotun Koli na Gambia a 2003.  Mambilima ta zauna a hukumar kula da alkalan mata ta duniya (IAWJ) a matsayin Darakta a yankin Afirka. Har ila yau, ta kasance memba na ƙungiyoyin ƙwararru da yawa da suka haɗa da Ƙungiyar Alƙalai ta Zambiya, Majalisar Edita na Rahoton Shari'a, Asusun Yara (Zambia), Mata a Dokar Kudancin Afirka, da Majalisar Cibiyar Ilimin Shari'a. Majalisar dokokin kasar ce baki daya ta amince da nadin Mambilima a matsayin Alkalin Alkalai a watan Fabrairun 2015, wanda ya zama mace ta farko mai shari’a a kasar. An haifi Mambilima a ƙauyen Chiwoko a lardin Gabas na zamani ga Kezias Chirwa mai yin bulo da matarsa Nelia Ngulube.