Olikoye Ransome-Kuti an haife shi ne a Ijebu Ode a ranar 30 ga watan Disamban shekara ta 1927, a cikin jihar Ogun ta yanzu, Nijeriya. Mahaifiyarsa, Cif Funmilayo Ransome-Kuti, shahararriyar mai rajin siyasa ce kuma mai rajin kare hakkin mata, kuma mahaifinsa, Reverend Israel Oludotun Ransome-Kuti, wani Furotesta minista kuma shugaban makarantar, shi ne shugaban farko na ƙungiyar Malaman Najeriya . An uwansa Fela zai girma ya zama mashahurin mawaƙa kuma ya kafa Afrobeat, yayin da wani ɗan'uwansa, Beko, zai zama fitaccen likita da ɗan gwagwarmaya na duniya. Ransome-Kuti ta halarci Makarantar Grammar ta Abeokuta, Jami’ar Ibadan da kuma Kwalejin Trinity ta Dublin (1948–54). Ya kasance likitan gida a General Hospital, Lagos . Ya kasance babban malami a jami'ar Legas daga shekara ta 1967 zuwa shekara ta 1970 sannan ya nada Daraktan kula da lafiyar yara a kwalejin koyon aikin likitanci ta jami'ar ta Legas sannan ya zama shugaban sashin kula da lafiyar yara daga shekara ta 1968 zuwa shekara ta 1976. Ya kasance farfesa a likitan yara a Kwalejin Magunguna, Jami'ar Legas har sai da ya yi ritaya a 1988.