Rebecca Naa Okaikor Akufo-Addo (née Griffiths-Randolph; an haife ta a 1951) 'yar asalin kasar Ghana ce kuma Uwargidan Shugaban kasar Ghana a yanzu a matsayin matar Shugaban kasa Nana Akufo-Addo, Shugaba na 5 na Jamhuriya ta 4 ta Ghana. Akufo-Addo ya halarci sashen firamare na makarantar Achimota. Tsohuwar dalibi ce a makarantar Wesley Grammar a Dansoman a yankin Greater Accra na Ghana. Ita 'yar alkali ce, Jacob Hackenburg Griffiths-Randolph wacce ta yi aiki a matsayin Shugaban Majalisar Ghana a Jamhuriya ta Uku da Frances Phillipina Griffiths-Randolph (née Mann). Rebecca Akufo-Addo ta ci gaba da karatunta a Makarantar Sakatariyar Gwamnati inda ta cancanci zama sakatare. Ta yi aiki a Bankin Kasuwanci da ke Ghana daga baya ta koma Ingila. Sannan ta yi aiki a matsayin sakatariyar shari'a ga Clifford Chance / Ashurst Morris Crisp dukkan kamfanonin lauyoyi na kasashe daban-daban a Ingila. An haifi Rebecca Akufo-Addo a ranar 12 ga Maris 1951. Ita mamba ce kuma shugabar kungiyar ba da agaji, Gidauniyar Rigakafin Cutar Malaria ta Infanta da aka kafa a 2005, don tallafawa kokarin kasa na rage kamuwa da zazzabin cizon sauro ga jarirai da kananan yara.