Karidjo Mahamadou ɗan siyasan Nijar ne. Babban jagora a jam'iyyar PNDS-Tarayya, ya yi aiki a gwamnatin Nijar a matsayin Ministan Tsaro na Kasa daga shekarar 2011 zuwa shekarar 2016. Ya kasance Shugaban Kotun Koli na Shari'a tun daga shekarar 2016. Malami ne ta hanyar kwarewa, Mahamadou ya kasance memba na kafa PNDS; lokacin da jam'iyyar ta gudanar da Babban Taronta a 23 – 24 watan Disamba shekarar 1990, an nada shi a matsayin Mataimakin Sakatare na farko na Kungiya. An zabe shi ga Majalisar Dokokin Nijar a matsayin dan takarar PNDS a zaben majalisar dokoki na watan Fabrairun 1993 . A cikin lokacin da ya biyo baya, ya yi aiki na wani lokaci a matsayin Shugaban Masarautar Maradi . A Taron Talakawa na hudu na PNDS, wanda aka gudanar a ranar 4 – 5 ga watan Satumba shekarar 2004, an zabi Mahamadou a matsayin Mataimakin Sakatare-Janar na Hudu. Ya ci gaba da rike wannan mukamin a Babban Taro na biyar, wanda aka gudanar a ranar 18 ga watan Yulin shekarar 2009.