Chukwuemeka Ezeife an zabe shi gwamnan jihar Anambra a Najeriya daga watan Janairun 1992 zuwa Nuwamba 1993 a lokacin Jamhuriya ta Uku ta Najeriya. An haifi Ezeife a Igbo-Ukwu, jihar Anambra a ranar 20 ga Nuwamba 1939. Bai halarci makarantar sakandare ba, amma ya koyar da kansa ta hanyar kwasa-kwasan rubutu, wanda ya cancanci shiga jami'a. Ya sami BSc a fannin Tattalin Arziki daga Kwalejin Jami’a ta Ibadan, sannan ya halarci Jami’ar Harvard a kan tallafin karatu na Rockefeller Foundation inda ya samu digiri na biyu sannan ya yi karatun digirin digirgir a 1972.  Ya zama Shugaban Makaranta, malami a Makarare University College, Kampala, Uganda, a Teaching Fellow a Harvard University, da kuma Mashawarci tare da Arthur D. Little a Cambridge, Massachusetts . Ezeife ta shiga aikin farar hula a matsayin Jami'in Gudanarwa har ta kai ga matsayin Babban Sakatare. An zabi Ezeife a matsayin gwamnan jihar Anambara a kan dandalin Social Democratic Party (SDP), yana rike da mukami daga 2 ga Janairu 1992 zuwa 17 Nuwamba 1993, lokacin da Janar Sani Abacha ya karbi mulki bayan juyin mulkin soja.