Makgadikgadi Pan /məˈkɑːdiˈkɑːdi / (lafazin Tswana [makχʰadiˈkχʰaːdi], kwanon gishirin da ke tsakiyar busassun savanna na arewa maso gabashin Botswana, ɗayan manyan gidaje ne na gishiri a duniya. Kwanon ruhun shine abin da ya saura na babban tafkin Makgadikgadi, wanda ya taɓa rufe yankin da ya fi Switzerland girma, amma ya bushe dubun dubatan shekaru da suka gabata. Karatun baya-bayan nan game da DNA na mitochondrial na mutum ya nuna cewa Homo sapiens na zamani sun fara rayuwa a wannan yankin shekaru 200,000 da suka gabata, lokacin da yake da fadi da keɓaɓɓen yanki na tabkuna, koguna, dausayi, dazuzzuka da filayen ciyayi musamman masu kyau wurin zama ta hanyar cigaban dabbobi da wasu dabbobi masu shayarwa. Da yake kwance a kudu maso gabas na Okavango Delta kuma kewaye da Hamadar Kalahari, Makgadikgadi a zahiri ba fanfo ɗaya ba ce, amma kwanuka da yawa tare da hamada mai yashi a tsakani, mafi girma shine Sua (Sowa), Nwetwe da Nxai Pans. Mafi girman kwanon rufi mutum kusan 1,900 sq mi (4,921.0 km2).