David Wayne (30 Januarie 1914 – 9 Februarie 1995) was 'n Amerikaanse akteur. Hy was bekend vir sy rolle in die rolprente Adam's Rib (1949), How to Marry a Millionaire (1953), The Andromeda Strain (1971), en The Front Page (1974). 1949: Adam's Rib 1950: My Blue Heaven 1950: The Reformer and the Redhead 1950: Stella 1951: As Young as You Feel 1951: M 1951: Up Front 1952: Wait Till the Sun Shines, Nellie 1952: With a Song in My Heart 1953: How to Marry a Millionaire 1953: Down Among the Sheltering Palms 1953: The I Donot Care Girl 1953: Tonight We Sing 1955: The Tender Trap 1956: The Naked Hills 1957: The Sad Sack 1957: The Three Faces of Eve 1959: The Last Angry Man 1961: The Big Gamble 1971: The Andromeda Strain 1971: The African Elephant 1974: The Front Page 1974: Huckleberry Finn 1975: Tubby the Tuba 1979: The Prize Fighter 1954: Producers' Showcase 1955: Ford Star Jubilee 1955: Norby 1962: Exploring 1964: The Bing Crosby Show 1971: The Good Life 1975: Ellery Queen 1979: House Calls 1959: The Strawberry Blonde 1962: Kings of Broadway 1974: The F.B.I. Story: The FBI Versus Alvin Karpis, Public Enemy Number One 1974: Return of the Big Cat 1975: It's a Bird...