Joe De Santis (15 Mei 1909 – 30 Augustus 1989) was 'n Amerikaanse akteur. Hy was bekend vir sy rolle in die rolprente Al Capone (1959) en Beau Geste (1966), en in die televisiereekse Playhouse 90 (1956) en 77 Sunset Strip (1958). 1959: Al Capone 1961: A Cold Wind in August 1966: Beau Geste 1966: And Now Miguel 1987: How Rare a Possession: The Book of Mormon 1949: Photocrime 1951: Crime Photographer 1956: Playhouse 90 1958: 77 Sunset Strip 1959: The Man from Blackhawk 1959: Doctor Mike 1960: Unsolved 1975: Katherine Joe De Santis in die Internet-rolprentdatabasis