tokens: In addition , the specific inhibitors of phospholipase C ( PLC - gamma ) , phosphatidylinositol 3 - kinase ( PI3K ) , p38MAPK , c - Jun N - terminal kinase ( JNK ) , and the Ras / Raf / mitogen - activated protein kinase ( MAPK ) signaling pathways blocked the potentiation of NGF - induced neurite outgrowth by SA4503 .