Scooby-Doo and Guess Who? is an American animated television series produced by Warner Bros. Animation and the thirteenth television series in the Scooby-Doo franchise. The series is produced by Chris Bailey.

The show first premiered on Boomerang's SVOD service on June 27, 2019, before making its linear debut on Cartoon Network on July 8, 2019, and on the Boomerang channel on October 1, 2020.

Premise 
Following a similar premise to The New Scooby-Doo Movies, the series focuses on the Mystery Inc. gang as they solve mysteries while encountering and being assisted by various celebrities and fictional characters, including crossovers with DC Comics and Hanna-Barbera characters.

Voice cast

Mystery, Inc. 

 Frank Welker as Scooby-Doo and Fred Jones
 Matthew Lillard as Shaggy Rogers
 Grey Griffin as Daphne Blake
 Kate Micucci as Velma Dinkley

Guest stars 

 Laila Ali
 Sean Astin
 Jessica Biel
 Terry Bradshaw
 Kimberly Brooks
 Alton Brown
 Carol Burnett
 Steve Buscemi
 Cher
 Joey Chestnut
 Sandy Duncan
 Jeff Dunham
 Darci Lynne Farmer
 Jeff Foxworthy
 Morgan Freeman
 Jim Gaffigan
 Ricky Gervais
 Johnny Gilbert
 Whoopi Goldberg
 Tim Gunn
 Gigi Hadid
 Jennifer Hale
 Halsey
 Mark Hamill
 Chloe Kim
 Liza Koshy
 Tara Lipinski
 Lucy Liu
 Macklemore
 Malcolm McDowell
 Kacey Musgraves
 Bill Nye
 Chris Paul
 Penn & Teller
 Axl Rose
 Kristen Schaal
 Sia
 Joseph Simmons
 Christian Slater
 Jason Sudeikis
 Wanda Sykes
 George Takei
 Kenan Thompson
 Alex Trebek
 Neil deGrasse Tyson
 Jaleel White
 Jane Wiedlin
 Billy Dee Williams
 "Weird Al" Yankovic
 Maddie Ziegler

Fictional guest characters include The Hex Girls, Steve Urkel, Wonder Woman, Sherlock Holmes, Batman, Alfred Pennyworth, Joker, Flash, Trickster, Magilla Gorilla, the Ghost of Abraham Lincoln, Blue Falcon and Dynomutt and the characters from The Funky Phantom.

Episodes

Season 1 (2019–20) 

 Revenge of the Swamp Monster! (with Chris Paul)
 A Mystery Solving Gang Divided (with Ghost of Abraham Lincoln)
 Peebles' Pet Shop of Terrible Terrors! (with Wanda Sykes)
 Elementary, My Dear Shaggy! (with Sherlock Holmes)
 Ollie Ollie In-Come Free! (with Ricky Gervais)
 The Scooby of a Thousand Faces! (with Wonder Woman)
 The Cursed Cabinet of Professor Madds Markson! (with Penn & Teller)
 When Urkel-Bots Go Bad! (with Steve Urkel)
 The Fastest Food Fiend! (with Jim Gaffigan)
 Attack of the Weird Al-Osaurus! (with "Weird Al" Yankovic)
 Now You Sia, Now You Don't! (with Sia)
 Quit Clowning! (with Kenan Thompson)
 What a Night, For a Dark Knight! (with Batman)
 The Nightmare Ghost of Psychic U! (with Whoopi Goldberg)
 The Sword, The Fox, and the Scooby-Doo! (with Mark Hamill)
 One Minute Mysteries! (with The Flash)
 Hollywood Knights! (with George Takei)
 The New York Underground! (with Halsey)
 Fear of the Fire Beast! (with Steve Buscemi)
 Too Many Dummies! (with Jeff Dunham and Darci Lynne Farmer)
 Dance Matron of Mayhem! (with Maddie Ziegler)
 The Wedding Witch of Wainsly Hall! (with Jeff Foxworthy)
 A Run Cycle Through Time! (with Malcolm McDowell)
 I Put A Hex On You! (with The Hex Girls)
 The High School Wolfman's Musical Lament! (with Christian Slater)
 Space Station Scooby (with Neil deGrasse Tyson and Bill Nye)

Season 2 (2020–2021) 

 The Phantom, The Talking Dog, and the Hot Hot Hot Sauce! (with Kacey Musgraves)
 The Last Inmate! (with Morgan Freeman)
 The Horrible Haunted Hospital of Dr. Phineas Phrag! (with Kristen Schaal)
 The Hot Dog Dog! (with Joey Chestnut)
 A Moveable Mystery! (with Gigi Hadid)
 The Feast of Dr. Frankenfooder! (with Alton Brown)
 A Fashion Nightmare! (with Tim Gunn)
 Scooby on Ice! (with Tara Lipinski)
 Caveman on the Half Pipe! (with Chloe Kim)
 The Crown Jewel of Boxing! (with Laila Ali)
 The Internet on Haunted House Hill! (with Liza Koshy)
 The 7th Inning Scare! (with Macklemore)
 The Dreaded Remake of Jekyll & Hyde! (with Sandy Duncan)
 Total Jeopardy! (with Alex Trebek)
 Dark Diner of Route 66! (with Axl Rose)
 Lost Soles of Jungle River! (with Jason Sudeikis)
 The Tao of Scoob! (with Lucy Liu)
 Returning of the Key Ring! (with Sean Astin)
 Cher, Scooby and the Sargasso Sea! (with Cher)
 The Lost Mines of Kilimanjaro! (with Jessica Biel)
 The Legend of the Gold Microphone! (with Joseph Simmons (Run-DMC))
 Scooby-Doo and the Sky Town Cool School! (with Billy Dee Williams)
 Falling Star Man! (with Terry Bradshaw)
 A Haunt of a Thousand Voices! (with Frank Welker, Grey DeLisle, Matthew Lillard and Kate Micucci)
 Scooby-Doo, Dog Wonder! (with Blue Falcon and Dynomutt)
 The Movieland Monsters! (with Carol Burnett)

Notes

American animated television series