San Lorenzo is the Italian and Spanish name for Saint Lawrence, the 3rd century Christian martyr. It may also be:

Places
Argentina
 San Lorenzo, Santa Fe
 San Lorenzo Department, Chaco
 Monte San Lorenzo, a mountain on the border between Argentina and Chile
Bolivia
 San Lorenzo, Tarija

Colombia
 San Lorenzo, Nariño

Costa Rica
 San Lorenzo, a district in Heredia Province

Dominican Republic
 San Lorenzo De Mao in Mao, Dominican Republic

Ecuador
 San Lorenzo, Ecuador, a sea port
 San Lorenzo Canton, Esmeraldas Province

El Salvador
 San Lorenzo, Ahuachapán
 San Lorenzo, San Vicente

Guatemala
 San Lorenzo, San Marcos
 San Lorenzo, Suchitepéquez

Honduras
 San Lorenzo, Valle

Italy
San Lorenzo (Naples), a neighborhood in central Naples
San Lorenzo, Calabria, a commune in the province of Reggio Calabria
San Lorenzo al Mare, a commune in the province of Imperia
San Lorenzo del Vallo, a commune in the province of Cosenza
San Lorenzo in Banale, a commune in Trentino
San Lorenzo in Campo, a commune in the province of Pesaro and Urbino
San Lorenzo (Bognanco), in the province of Verbano Cusio Ossola
Colonne di San Lorenzo, Roman ruins in Milan
Quartiere San Lorenzo, part of the Third Municipality of Rome
San Lorenzo Bellizzi, a commune in Cosenza
San Lorenzo Isontino, a commune in Gorizia
San Lorenzo Maggiore, a commune and town in Benevento
San Lorenzo Nuovo, a commune in Viterbo
St Lorenzen, a commune in South Tyrol, in the Italian region Trentino-Alto Adige/Südtirol

Mexico
 San Lorenzo, Chihuahua
 San Lorenzo, Oaxaca
 San Lorenzo, Mexico State, site of some wrestling matches of El Hijo del Santo
 San Lorenzo Tenochtitlán, an ancient center of the Olmec culture, in Veracruz

Nicaragua
 San Lorenzo, Boaco

Paraguay
 San Lorenzo, Paraguay, a city to the east of Asunción

Peru
 San Lorenzo Island, Peru, an island in the Pacific off the coast of Callao
 San Lorenzo, Loreto

Philippines
 San Lorenzo, Guimaras
 San Lorenzo Ruiz, Camarines Norte, a 5th class municipality in the province of Camarines Norte
 San Lorenzo, a village in Makati

Spain
San Lorenzo de El Escorial, Madrid, a municipality in Madrid
Mount San Lorenzo, a mountain near Ezcaray in Sierra de la Demanda, La Rioja

United States
 San Lorenzo, Puerto Rico
 San Lorenzo, California, a town in Alameda County, California
 San Lorenzo River, in California
 San Lorenzo Valley, in California

Fictional
San Lorenzo (Vonnegut), a Caribbean island nation in Cat's Cradle by Kurt Vonnegut
San Lorenzo, a Central American country in Hey Arnold!: The Movie
San Lorenzo, a European country in Leverage

Churches
Italy
San Lorenzo in Panisperna, a basilica in Rome
San Lorenzo in Lucina, a church in Rome
San Lorenzo, Venice, a deconsecrated church in Venice
Basilica di San Lorenzo di Firenze, a church in Florence
Basilica di San Lorenzo fuori le Mura, a basilica in Rome
Genoa Cathedral or Cattedrale di San Lorenzo, a cathedral in Genoa
Perugia Cathedral or Cattedrale di San Lorenzo, a cathedral in Perugia
Basilica of San Lorenzo, Milan or Chiesa di San Lorenzo Maggiore, a church in Milan

Philippines
Binondo church or Minor Basilica of San Lorenzo Ruiz, a church in Manila

Spain
Church of San Lorenzo, Toledo

Sports
 San Lorenzo de Almagro, an Argentinian football club
 Club Sportivo San Lorenzo, a Paraguayan football club

Other
 "San Lorenzo", a song from the album Pat Metheny Group
San Lorenzo (restaurant), a restaurant in London, England, UK