This is a list of famous residents of St. Louis or St. Louis County, Missouri. The dates in parentheses signify lifespan, not necessarily dates of actual residence in the city.

A

 Brooke Adams (born 1984), professional wrestler, best known as Brooke Tessmacher
 Akon (born 1973), real name Aliaune Damala Badara Akon Thiam; musician
 Devon Alexander (born 1987), professional boxer, IBF welterweight world champion
 Raleigh DeGeer Amyx (born 1938), collector of Olympic and Presidential memorabilia
 Maya Angelou (1928–2014), poet, playwright, memoirist (I Know Why the Caged Bird Sings)
 Eberhard Anheuser (1805–1880), businessman, owner of company that would become Anheuser-Busch
 Noah Antwiler (born 1980), Internet comedian (The Spoony Experiment)
 Henry Armstrong (1912–1988), professional boxer, welterweight champion 1938–1940
 Dick Ault (1925-2007), American track and field athlete

B

 Josephine Baker (1906–1975), dancer, singer, actress, Légion d'Honneur appointee, civil rights activist
 Scott Bakula (born 1954), actor (Quantum Leap, Star Trek: Enterprise)
 James F. Ballard (1851–1931), pharmaceutical entrepreneur, and art collector
 Thomas P. Barnett (1870–1929), architect and impressionist painter
 Fontella Bass (1940–2012), soul and R&B singer ("Rescue Me")
 Cool Papa Bell (1903–1991), Negro League baseball player, Hall of Fame member
 Robert Benecke (1835-1903), early photographer
 Graham Bensinger, sports journalist for ESPN Radio
 Sally Benson, author whose short stories became the book, then movie Meet Me in St Louis
 Yogi Berra (born 1925), Major League Baseball player (New York Yankees 1946–1963), manager, coach, Hall of Famer
 Chuck Berry (born 1926), Rock and Roll Hall of Fame musician and composer ("Johnny B. Goode")
 Fred Berry (1951–2003), actor (What's Happening!!)
 Joe Besser (1907–1988), actor, comedian, member of The Three Stooges
 Jud Birza (born 1989), model, winner of Survivor: Nicaragua
 Linda Blair (born 1959), actress (The Exorcist)
 Sean Blakemore, actor, Shawn Butler on ABC's General Hospital
 Susan Blow (1843–1916), educator, opened first successful public kindergarten in U.S.
 Kit Bond (born 1939), U.S Senator from Missouri
 Daniel Boone (1734–1820), explorer, hunter, soldier, businessman, politician
 Evan Bourne (born 1983), WWE professional wrestler
 Martin Stanislaus Brennan (1845–1927), Catholic priest and scientist
 Christine Brewer (born 1955), Grammy Award winner, soprano
 Lottie Briscoe (1883-1950), stage and silent film actress
 Lou Brock (born 1939), Major League Baseball player (St. Louis Cardinals 1964–1979), Hall of Famer
 Shirley Brown (born 1947), soul/R&B singer ("Woman to Woman")
 Evan Bourne, real name Matthew Korklan, WWE wrestler
 Butch Buchholz (born 1940), Hall of Fame tennis player
 Jack Buck (1924–2002), Hall of Fame sportscaster, St. Louis Cardinals' announcer 1969–2002
 Joe Buck (born 1969), sportscaster, football and baseball announcer for Fox, son of Jack Buck
 Mark Buehrle (born 1979), Major League Baseball pitcher (Chicago White Sox, Toronto Blue Jays)
 Grace Bumbry (born 1937), opera singer
 T-Bone Burnett (born 1948), rock and country performer, composer, and producer
 William S. Burroughs (1914–1997), novelist, social critic, spoken-word performer; grandson of inventor William Seward Burroughs I
 William Seward Burroughs I (1855–1898), inventor of adding machine, founder of Burroughs Corporation; grandfather of novelist William S. Burroughs
 Adolphus Busch (1839–1913), co-founder of Anheuser-Busch with father-in-law Eberhard Anheuser
 Adolphus Busch III (1891–1946), president and CEO of Anheuser-Busch; son of August Anheuser Busch, Sr.
 August Anheuser Busch, Sr. (1865–1934), president and CEO of Anheuser-Busch; son of Adolphus Busch
 Gussie Busch (August Anheuser Busch, Jr.) (1899–1989), president and CEO of Anheuser-Busch, civic leader, philanthropist
 August Busch III (born 1937), president and CEO of Anheuser-Busch, civic leader
 August Busch IV (born 1964), president and CEO of Anheuser-Busch, civic leader
 Norbert Leo Butz (born 1967), Tony Award-winning actor

C
 Thomas Cahill (1864–1951), athlete, coach, businessman; a founding father of American soccer
 Kate Capshaw (born 1953), actress (Indiana Jones and the Temple of Doom), wife of Steven Spielberg
 Chip Caray (born 1965), sportscaster for Chicago Cubs, Atlanta Braves and Fox
 Harry Caray (1914–1998), sportscaster, lead announcer for the St. Louis Cardinals (1945–1969) and Chicago Cubs (1981–1997)
 Skip Caray (1939–2008), sportscaster, announcer for the Atlanta Braves (1976–2008)
 Nell Carter (1948–2003), Tony Award-winning singer and actress (Ain't Misbehavin')
 Louis Cella (1866-1918), capitalist, real estate mogul, turfman, and political financier.
 Cedric the Entertainer (born 1964), comedian and actor
 Lori Chalupny (born 1984), U.S. women's national soccer team member
 C. J. Cherryh (born 1942), science-fiction novelist
 Chingy (born 1980), real name Howard Bailey, Jr., hip-hop recording artist and actor
 Kate Chopin (1851–1904), novelist (The Awakening)
 Auguste Chouteau (1740–1829), co-founder of St. Louis, urban planner, businessman, civic leader
 David Clarenbach (born 1953), member of Wisconsin State Assembly
 Patrick Clark, television reporter and host
 William Clark (1770–1838), explorer, government administrator
 Sarah Clarke (born 1972), actress (24)
 Mac Cody (born 1972), football player in NFL, CFL, AFL
 Andy Cohen (born 1968), television executive and personality at Bravo network, one of the first openly gay talk-show hosts
 Barry Commoner (born 1917), biologist, college professor, eco-socialist, and presidential candidate
 Arthur Compton (1892–1962), physicist, Nobel Prize in Physics 1927
 Jimmy Connors (born 1952), professional tennis player, 5-time U.S. Open winner in men's singles
 Bert Convy (1933–1991), actor and game-show host
 Carl Ferdinand Cori (1896–1984); Gerty Cori (1896–1957), biochemists, joint Nobel Prize in Physiology or Medicine 1947
 Bob Costas (born 1952), sportscaster, talk-show host
 Bryan Cox (born 1968), NFL linebacker 1991–2002
 Jim Cox (born 1920), professional football player
 Lavell Crawford (born 1968), stand-up comedian, actor
 Kalel Cullen (born 1989), YouTube personality, animal rights activist

D
 John Danforth (born 1936), statesman, diplomat, attorney, civic leader, U.S. Senator 1977–1995
 William H. Danforth (1870–1956), founder of Ralston Purina Company; grandfather of John Danforth and William H. "Bill" Danforth
 William H. "Bill" Danforth (born 1926), physician, professor of medicine, and chancellor of Washington University in St. Louis 1971–1995
 Billy Davis, Jr. (born 1940), R&B and soul singer, member of The 5th Dimension
 Dwight F. Davis (1879–1945), athlete, government administrator
 Miles Davis (1926–1991), musician, winner of Grammy Lifetime Achievement Award
 Dizzy Dean (1910–1974), baseball pitcher, broadcaster
 Dan Dierdorf (born 1949), football player, broadcaster
 Phyllis Diller (1917–2012), comedian
 L. John Doerr (born 1951), venture capitalist
 Domino (born 1972), real name Shawn Antoine Ivy, rapper, born in St. Louis
 Colin Donnell (born 1982), actor, Arrow
 Thom Donovan (born 1974), musician (Lapush)
 Jack Dorsey (born 1976), software architect and businessperson, creator of Twitter and Square
 Bob Dotson (born 1946), broadcast journalist, NBC correspondent
 Katherine Dunham (1909–2006), dancer
 Tim Dunigan (born 1955), actor

E
 James Eads (1820–1887), engineer
 Thomas Eagleton (1929–2007), statesman, attorney, civic leader
 Charles Eames (1907–1978), designer, filmmaker
 William Edenborn (1848–1926), industrialist and inventor
 T. S. Eliot (1888–1965), poet (Nobel Prize, Presidential Medal of Freedom), critic
 William Greenleaf Eliot (1811–1887), educator, medical reformer, civil rights activist; grandfather of T. S. Eliot
 Stanley Elkin (1930–1995), author
 Preston Elliot, radio personality, Preston and Steve on WMMR in Philadelphia
 Mary Engelbreit (born 1952), artist
 Walker Evans (1903–1975), photographer
 Steve Ewing, singer/actor, The Urge

F
 Max Factor (1904–1996), cosmetics maker
 Lee Falk (1911–1999), comic strip creator
 Eugene Field (1850–1895), author
 Curtis Finch, Jr. (born 1988), American Idol Season 12 contestant
 Shandi Finnessey (born 1978), Miss USA 2004
 Jenna Fischer (born 1974), actress
 Jamar Fletcher (born 1979), professional football player
 Jason Fletcher (born 1975), sports agent
 Ellen Foley (born 1951), singer, actress
 Richard Fortus (born 1966), musician, Guns N' Roses
 Redd Foxx (1922–1991), comedian, actor
 James Franciscus (1934–1991), actor (Mr. Novak, Longstreet)
 Mary Frann (1943–1998), actress (Newhart)
 Jonathan Franzen (born 1959), author
 David Freese (born 1983), baseball player

G
 Bob Gale (born 1951), screenwriter, film producer
 Alberta Gallatin (1861-1948), stage and screen actress, raised in St. Louis
 Pud Galvin (1856–1902), Major League Baseball player
 Joe Garagiola (born 1926), baseball player, sportscaster, television personality, author
 Jan Garavaglia (born 1956), Chief Medical Examiner of the District 9 Morgue in Orlando, Florida; television personality
 Dave Garroway (1913–1982), television personality, first host of NBC's Today Show
 William H. Gass (born 1924), author, critic
 Taylor Geisse, Octomom
 Martha Gellhorn, author and journalist; third wife of Ernest Hemingway
 Richard Gephardt (born 1941), politician
 Steve Gerber (1947–2008), comic-book writer, co-creator of Howard the Duck
 Frances Ginsberg (1955–2010), opera singer
 David Giuntoli (born 1981), actor
 John Goodman (born 1952), actor
 Harry Goz (1932-2003), actor, Sealab 2021
 Betty Grable (1916–1973), actress
 Ulysses S. Grant (1822–1885), Civil War general and 18th President of the United States
 Grant Green (1935–1979), jazz guitarist
 Trent Green, football player
 Dick Gregory (born 1932), comedian, civil rights activist
 Charles Guenther, poet, translator, newspaper critic
 Robert Guillaume (born 1927), Grammy and Emmy Award-winning actor
 James Gunn, screenwriter, director
 Sean Gunn, actor
 Moses Gunn, actor

H
 Laurell K. Hamilton, author
 Jon Hamm (born 1971), Golden Globe award-winning actor, Mad Men
 Henry Hampton (1940–1998), film producer, Eyes on the Prize: America's Civil Rights Years (1954-1965) and Eyes on the Prize II: America at the Racial Crossroads (1965-1980s)
 Sally Hampton (born 1958), writer, producer
 Chuck T. Harmon aka Chuck Harmony, music producer for Mary J. Blige, Celine Dion, Fantasia, Rihanna
 Doris Hart (born 1925), Hall of Fame tennis player, two-time U.S. Open champion
 John Hartford (1937–2001), musician, Grammy Award winner
 Culver Hastedt (1883-1966), runner, gold medal winner at 1904 Summer Olympics
 Donny Hathaway (1945–1979), Grammy-winning singer, songwriter, producer, composer
 Pat Healy, mixed martial arts fighter
 Julius Hemphill (1938–1995), jazz saxophonist, composer
 George E. Hibbard (1924–1991), art collector, advocate for Tibetan Independence
 George Hickenlooper, filmmaker
 Al Hirschfeld (1903–2003), artist and cartoonist
 Bobby Hofman (1925-1994) Major League Baseball player
 Solly Hofman (1882-1956), Major League Baseball player
 Robert A. Holekamp (1848–1922), businessman and apiarist
 Ken Holtzman (born 1945), baseball pitcher
 A. E. Hotchner (born 1920), author, editor, philanthropist
 Elston Howard, baseball player, first black player for New York Yankees
 Ryan Howard (born 1979), baseball player, 2005 NL Rookie of the Year, 2006 National League MVP and All-Star first baseman, Philadelphia Phillies
 Huey (born 1988), real name Lawrence Franks, Jr. , rapper
 Larry Hughes, basketball player, Chicago Bulls

I
 Vedad Ibišević (born 1984), Bosnian soccer player
 William Inge (1913–1973), Pulitzer Prize-winning playwright
 Ernie Isley, songwriter, guitarist of soul and R&B group The Isley Brothers
 Ronald Isley, lead singer of The Isley Brothers; co-owns St. Louis-based Notifi Records
 Halsey Ives (1847–1911), museum and school founder, director of two world-fair art exhibitions (Louisiana Purchase Exposition and World's Columbian Exposition)

J
 Sean James (born 1978), athlete
 Cam Janssen, ice hockey player
 Ella Jenkins, musician
 Jibbs (born 1990), real name Jovan Campbell, rapper
 J-Kwon (born 1986), real name Jerrell Jones, rapper
 Johnnie Johnson (1924–2005), musician
 Justine Joli, adult-film actress
 Scott Joplin, songwriter (Pulitzer Prize), musician, "King of Ragtime"
 Jackie Joyner-Kersee, Olympic gold-medalist track & field athlete; educator; sister of Olympic athlete Al Joyner; sister-in-law of Florence "Flo Jo" Griffith-Joyner

K
 Kane (born 1967), real name Glenn Jacobs, professional wrestler
 Stan Kann (1924–2008), musician, entertainer
 Bruce Karsh (born 1955), lawyer and investor
 Ben Kasica (born 1984), musician
 Andreas Katsulas (1946–2006), actor
 David Kaufman (born 1969), character actor and voice actor (Danny Phantom)
 Jim Kekeris (born 1923), NFL player
 Ellie Kemper (born 1980), actress, The Office
 Dorothea Kent (1916–1990), film actress
 Dickie Kerr (1893–1963), baseball pitcher
 Imrat Khan (born 1935), Indian classical musician
 Albert King (1923–1992), musician
 Silver King (1868–1938), Major League Baseball player
 Kevin Kline (born 1947), Academy Award-winning actor
 Karlie Kloss (born 1992), model

L
 Pierre Laclede (1729-1778), urban planner; co-founder of St. Louis; government administrator; civic leader
 Pat LaFontaine (born 1965), NHL hockey player
 Elizabeth Laime, podcaster, writer
 Oliver Lake (born 1942), jazz saxophonist, composer
 Christopher Largen (born 1969), author, filmmaker, journalist, activist
 David Lee (born 1983), NBA basketball player
 Jim Lee (born 1964), comic book artist, writer and publisher
 Murphy Lee, rapper
 Tod Leiweke (born 1960), sports executive
 Maggie LePique (born 1964), jazz radio host
 Stacey Levine, fiction writer, journalist
 Jenifer Lewis (born 1957), actress
 Charles Lindbergh (1902–1974), adventurer, pilot, soldier, author
 Theodore Link (1850–1923), architect
 Sonny Liston (1932–1970), heavyweight champion boxer

M
 Vicki Mabrey (born 1956), broadcast journalist
 Ed Macauley, Hall of Fame basketball player
 Al MacInnis (born 1963), Hall of Fame defenseman and VP of Hockey Operations for (St. Louis Blues)
 Jeremy Maclin (born 1988), football wide receiver (Philadelphia Eagles)
 James S. Marshall, Mayor of Green Bay, Wisconsin
 Peter Martin (born 1970), jazz pianist
 Marsha Mason, Golden Globe Award-winning and Oscar-nominated actress
 Masters and Johnson, medical researchers and therapists, authors
 Stan Masters (1922–2005), American realism artist
 Ron Mathis (1958–1980), Major League baseball player
 Bill Mauldin (1921–2003), cartoonist, Pulitzer Prize winner
 Morton D. May, philanthropist, community leader, art collector, chairman of May Department Stores
 Virginia Mayo, actress
 Emmett McAuliffe, lawyer and talk show host
 Jimmy McCracklin (born 1921), pianist, vocalist and songwriter
 Michael McDonald, singer, Grammy Award winner
 Robert McFerrin, Sr., classical singer; father of Bobby McFerrin
 Robert McHenry, encyclopedist and author
 Jim McKelvey (born 1965), computer science engineer, co-founder of Square, a mobile payments company
 Chuck McKinley, Hall of Fame tennis player, 1963 Wimbledon champion
 Ben McLemore (born 1993), basketball player
 George McManus, creator of comic strip Bringing Up Father
 Larissa Meek (born 1978), Miss Missouri Teen USA 1997, Miss Missouri 2001, creative director at BGT Partners
 Javier Mendoza, singer-songwriter and composer
 David Merrick, theatrical producer (Tony Awards)
 Joyce Meyer (born 1943), religious preacher and speaker
 Jay Miller, basketball player
 Russ Mitchell (born 1960), journalist and television news anchor
 Taylor Momsen, singer-songwriter, model, actress
 Archie Moore, boxer, world light-heavyweight champion
 Marianne Moore, poet (Pulitzer Prize), essayist, translator
 Agnes Moorehead, Emmy Award-winning and Oscar-nominated actress
 Bill Mueller, baseball player
 Nick Murphy, NFL punter 2002–2005
 Stan Musial (1920–2013), Hall of Fame baseball player for the St. Louis Cardinals

N
 Nelly (born 1974), real name Cornell Haynes, Jr., rapper, singer and actor
 Howard Nemerov (1920–1991), poet (Pulitzer Prize, Poet Laureate of the United States), author, critic
 Dustin Nguyen, Vietnamese American actor
 Rich Niemann (born 1946), athlete
 Frank Nuderscher (1880–1959), American Impressionist painter

O
 Dan O'Bannon, screenwriter, director
 Gyo Obata, architect
 St. Louis Jimmy Oden (1903–1977), real name James Burke Oden, blues musician
 Franklin W. Olin (1860–1951), industrialist, philanthropist
 Walter J. Ong, scholar
 Barry Orton, former professional wrestler
 "Cowboy" Bob Orton, former professional wrestler
 Randy Orton, professional wrestler
 Josh Outman, Major League Baseball player, Oakland Athletics

P
 Ken Page (born 1954), actor, voice actor, cabaret singer
 John Pankow (born 1954), actor (Beverly Hills Cop, Mad About You)
 King Parsons (born 1949), professional wrestler
 Ann Peebles (born 1947), soul singer, songwriter
 D.H. Peligro, real name born Darren Henley, drummer for Dead Kennedys and Red Hot Chili Peppers
 Frank P. Pellegrino (1901-1975), businessman, philanthropist, chief executive officer of International Hat Company
 Marlin Perkins (1905–1986), zoologist, Emmy Award-winning broadcaster
 Evan Peters (born 1987), actor (American Horror Story)
 Mike Peters, Pulitzer Prize-winning editorial cartoonist and comic strip artist, creator of Mother Goose and Grimm
 Stone Phillips (born 1954), television journalist
 Julie Piekarski (born 1963), Mouseketeer, actress
 Louise Post (born 1966), musician (Veruca Salt)
 Emil Preetorius (1827–1905), journalist
 Vincent Price (1911–1993), actor (House of Wax, The Ten Commandments, The Fly, Edward Scissorhands)
 Victor Proetz (1897–1966), architect, designer, author of poetry and verse
 Chris Pronger (born 1974), hockey player (St. Louis Blues, Philadelphia Flyers)
 Joseph Pulitzer (1847–1911), publisher, philanthropist, creator of the Pulitzer Prize
 Ashley Purdy (born 1984), bassist of Black Veil Brides

R
 Neil Rackers (born 1976), athlete, placekicker for Arizona Cardinals
 Harold Ramis (1944–2014), author, director, actor; graduated from Washington University (1966)
 Judy Rankin (born 1945), professional golfer and TV commentator, World Golf Hall of Famer
 David Rasche (born 1944), actor
 Peter H. Raven (born 1936), botanist, academic administrator, civic leader
 Hank Raymonds (1924–2010), coached Marquette University men's basketball 1977-83; athletic director 1977-87
 Tim Ream, professional soccer player, defender for Bolton Wanderers of Football League Championship and United States men's national soccer team
 Wallace Reid (1891–1923), actor, early cinema sex symbol
 Hadley Richardson (1891–1979), first wife of Ernest Hemingway
 Branch Rickey (1881–1965), baseball executive
 Rob Riti (born 1976), football player
 Doris Roberts (born 1930), actress (Everybody Loves Raymond)
 Leonard Roberts (born 1972), actor
 Lance Robertson (born 1965), musician and host of children's television show Yo Gabba Gabba! (as DJ Lance Rock)
 Harry Rogers (born 1950), professional basketball player
 Irma S. Rombauer (1877–1962), author
 William B. Roth (born 1963), actor, producer
 Jean Rouverol (born 1916), author, actress and screenwriter; blacklisted in the 1950s
 Jack Rowe (1856–1911), major league baseball player
 Charles M. Russell (1864–1926), artist, storyteller

S
 John S. Samuel, U.S. Air Force Major General
 David Sanborn, musician, Grammy Award winner
 Edward Saxon, film producer (The Silence of the Lambs)
 Max Scherzer, MLB pitcher
 Phyllis Schlafly, socially conservative Republican author, broadcaster, and political organizer
 Zander Schloss, bassist for the Circle Jerks and The Weirdos; actor
 Red Schoendienst, Hall of Fame second baseman, coach, manager for St. Louis Cardinals
 Chris Schuler, professional soccer player for Real Salt Lake
 Dred Scott (1799–1858) and Harriet Scott (1815–1860), civil rights activists
 Art Shamsky, Major League Baseball outfielder and Israel Baseball League manager
 Mike Shannon (born 1939), affiliated with St. Louis Cardinals for over 50 years, as a player (1962–1970), in front office, and, since 1972, radio and TV announcer
 Henry Shaw (1800–1889), botanist, philanthropist, businessman, author
 William Tecumseh Sherman (1820–1891), soldier; commander of United States Army
 Sherman Silber, physician and infertility specialist
 Frank Simek, soccer player with Sheffield Wednesday, also USA International
 Kimora Lee Simmons (born 1975), model and mogul
 Leonard Slatkin, conductor, Grammy Award winner
 Jane Smiley (born 1949), Pulitzer Prize-winning novelist
 Nikko Smith, singer, American Idol contestant; son of Ozzie Smith
 Ozzie Smith, Hall of Fame shortstop for St. Louis Cardinals
 Phyllis Smith, actress on NBC's The Office and Disney's movie Inside Out
 Willie Mae Ford Smith, singer
 Philip Sneed, singer, musician (Story Of The Year, Greek Fire), writer, radio personality
 Corey Spinks, world champion boxer
 Leon Spinks, world champion boxer
 Michael Spinks, world champion boxer
 Paul Stastny, hockey player for St. Louis Blues
 Yan Stastny, hockey player for St. Louis Blues
 Harry Steinfeldt, Major League Baseball player
 Edward Steinhardt (born 1961), poet and author
 Chuck Stone (born 1924) journalist, educator and civil rights activist
 Stevie Stone, rapper, born in Columbia, raised in St. Louis, signed to Kansas City-based Strange Music
 Willie Sudhoff, Major League Baseball player
 Roosevelt Sykes (1906-1983), blues musician
 James W. Symington, U.S. Representative, statesman, attorney
 SZA (born 1990), real name Solana Rowe, singer-songwriter, TDE (Top Dawg Entertainment) record label

T

 Jim Talent (born 1956), politician
 Sara Teasdale (1884–1933), poet (Pulitzer Prize)
 Clark Terry, musician
 George Thampy (born 1987), 2000 Scripps National Spelling Bee champion
 Lou Thesz, professional wrestler
 Kay Thompson (1909-1998), singer, songwriter, author of Eloise books
 Cap Tilles (1865-1951), race track magnate, philanthropist, founder of Tilles Park
 Gina Tognoni (born 1973), actress
 Guy Torry (born 1969), actor and comedian
 Joe Torry (born 1965), actor and comedian
 Henry Townsend, musician
 Toya (born 1983), real name LaToya Rodriguez, R&B singer
 Helen Traubel, classical and popular singer
 Quincy Troupe, poet, editor, journalist
 Ernest Trova, artist
 Ross H. Trower, Chief of Chaplains of U.S. Navy
 Truth Hurts (born 1971), real name Shari Watson, R&B singer
 Orrin Tucker (born 1911), bandleader
 Debbye Turner, Miss America 1990, TV journalist
 Ike Turner (1931–2007), singer, musician, agent and production administrator
 Tina Turner, real name Anna Mae Bullock, Grammy Award-winning singer, actress, pop-culture icon
 Taylor Twellman (born 1980), professional soccer player
 Alex Tyus (born 1988), American-Israeli professional basketball player, also plays for Israeli national basketball team

U
 David King Udall (1851–1938), politician

V
 Mark Valenti, screenwriter and novelist
 Mona Van Duyn, poet (Pulitzer Prize, Poet Laureate of the United States), editor
 George Van Haltren, Major League Baseball player
 Andrew Volpe, guitarist and lead singer of the St. Louis-based band Ludo
 Marilyn vos Savant, columnist, known for having the world's highest IQ

W
 Jack Wagner, actor
 Kenny Wallace (born 1963), NASCAR driver
 Mike Wallace (born 1959), NASCAR driver
 Rusty Wallace (born 1956), NASCAR champion driver
 Steve Wallace (born 1987), NASCAR driver
 Trey Waltke (born 1955), tennis player, won ATP title in 1980
 Maxine Waters (born 1938), politician
 Earl Weaver (1930–2013), Hall of Fame baseball manager
 Dick Weber (1929–2005), professional bowler
 Harry Weber (born 1942), sculptor
 Dave Weckl (born 1960), musician, drummer
 Annie Wersching (born 1977), actress, played Renee Walker on TV series 24
 Jo Jo White (born 1946), basketball player
 Verner Moore White (1863–1923), artist
 Marissa Whitley, Miss Teen USA 2001
 Mary Wickes (1910–1995), actress
 Violet Wilkey (1903–1976), actress
 Melvin Williams (born 1979), NFL player
 Tennessee Williams (1911–1983), real name Thomas Lanier, Pulitzer Prize-winning playwright
 Mykelti Williamson (born 1957), actor, played Bubba Blue in 1994 film Forrest Gump
 Ike Willis (born c. 1957), musician
 Angela Winbush (born 1955), R&B/soul singer, songwriter
 Matt Winer, sports journalist (KSDK-TV, ESPN)
 Trey Wingo (born 1955), sports journalist (KSDK-TV, ESPN)
 Kellen Winslow (born 1957), NFL football player, Hall of Famer
 Shelley Winters (1920–2006), Academy Award-winning actress
 Edwin E. Woodman, Wisconsin State Senator
 Harriett Woods (1927–2007), politician; two-time Democratic nominee for the U.S. Senate from Missouri; former Lieutenant Governor
 Dan Wool, musician, composer with group Pray for Rain
 Robert M. Wright, farmer near St. Louis, state representative from Dodge City

X-Y-Z
 Clyde X (1931-2009), leader in the Nation of Islam

References

Other websites

 St. Louis African-American Biography Master Index
 St. Louis artists
 St. Louis and Missouri authors
 St. Louis Media Archives: Guide to Collections
 St. Louis Walk of Fame
 St. Louis Women's Biography Master Index

Lists of people from Missouri