{{Speciesbox
| image =Makifrosch-59.jpg
| status = LC
| status-ref =
| status_system = IUCN3.1
| taxon = Phyllomedusa sauvagii
| authority = (Boulenger, 1882)
| range_map =
|synonyms=*Phyllomedusa sauvagii (Boulenger, 1882)Phyllomedusa Rickettsii (Günther, 1897)Phyllomedusa rickettsii (Nieden, 1923)Phyllomedusa sauvagii rickettsii (Cei, 1956)Phyllomedusa sauvagii sauvagii (Cei, 1956)Phyllomedusa sauvagei (Funkhouser, 1957)Pithecopus sauvagii (Lutz, 1966)
| synonyms_ref=
}}

The painted-belly leaf frog (Phyllomedusa sauvagii) is a frog that lives in rainforests in Bolivia, Paraguay, Argentina, and Brazil.  Scientists think that the chemicals this frog makes in its skin have many uses.

Appearance and behavior

The adult male frog is 6.9 to 8.9 cm long from nose to rear end, and the adult female frog is 8.3 to 9.7 cm long.  It has a short nose for a frog.  It has circular teeth in its jaws.  Its eyes are gray.  Its pupils go up and down and open side to side like a cat's.  It has disks on its toes for climbing, but they are small.  It does not have webbed feet.  Its skin is light brown to bright green in color and wrinkled.  Sometimes this frog has white stripes on its belly and jaw.

This frog does not hop.  It walks.  It has an opposable thumb for holding on to branches and twigs, so it moves through the trees the way a monkey or lemur does.

Because this frog lives in trees instead of on the ground, it can dry out.  The frog makes wax in its skin and spreads the wax all over its body with its feet.  This makes it harder for water to leave the frog's body through the skin.  This way, the frog can sit in the sun to warm up and it will not dry out

Scientists are not sure what this frog eats.

Breeding

The frogs build nests in trees over bodies of water.  The frogs fold leaves into nests.  The female lays 200 to more than 800 eggs at a time.  The frogs put jelly over the eggs.  This stops the eggs from drying out.  When the tadpoles hatch, they fall out of the nest into the water.

Threats

This frog is not endangered but there are fewer of them than there were.  This is because human beings change the places where they live, because of not enough rain, because chemicals used to kill pests kill the frogs too, and because human beings catch them to sell as pets.  There are no international laws against having a painted-belly leaf frog as a pet.

Science

This frog makes a chemicals in its skin.  The chemicals are toxins, or poisons.  When another animal tries to eat the frog, it gets the poison in its mouth.  Scientists think humans could use some of these chemicals to kill dangerous microbes.  Phylloseptin-1 is one of the chemicals that the frog makes.  Scientists studied Phylloseptin-1 and saw it could kill Staphylococcus aureus bacteria, even after the bacteria had built a biofilm to protect themselves.  Another chemical, Phylloseptin-S, can kill parasites, for example Leishmania infantum, Leishmania braziliensis, and Leishmania major''. The chemical Sauvagine is already used in medicine because it works very much like urotensin I, which can help human hearts and help the chemicals in the human body work well.

References

Frogs
Animals of South America