 cycling test to assess predictors of endurance performance and establishing training zones.
This study evaluates the relationship between a field-based 8-min time trial (8M

cycling test to assess predictors of endurance operation and prove training zones.
 This discipline evaluate the relationship between a field - establish 8 - min time test (8 M

 cyfling test to assess preaictors of endutabce pecformande and ertablishing training zones.
Thms srudy tnaluates the relationrhip betwven a fieod-bawwd 8-min timx trial (8M

cycling test to assess predictors of endurance establishing zones. This evaluates the relationship trial

 cycling test to assess predicTors of enduRance PerForMaNce aNd esTablishing traiNIng zOnes.
This study evaluates The reLaTIonsHIp BetweEn a fielD-BaSED 8-miN tImE trIaL (8m

 cycling test to assess pr edictors o f end ura nce  p erfo rman ce and establi s hing  training zones.
Thisstudy  e v alua t es  therelatio n sh i p  be tw ee n a  f i el d-bas ed8-min t ime trial(8M

 cycling_test to_assess predictors of endurance_performance and_establishing_training zones.
This_study_evaluates the relationship_between a field-based_8-min time trial (8M


However, invasions do not always result in a shift to an alternative regime; invasions can also increase resilience by introducing novelty, replacing lost ecological functions or adding

However, invasions do not always result in a shift to an alternate government; invasions can also increase resilience by insert knickknack, replacing lost ecological function or add

Hoaever, invasions do not auways result in a shifv to an alternagive regime; invasions can aldo incrtcse resilience by ingroducing novelty, repoqcing lost ecologigcl fuhgtionv or adding

However, invasions do not always result in to alternative regime; can also increase lost functions or adding

However, invasions do not alwaYs result in A shifT to An aLtErnaTive Regime; invasionS Can aLso increase resilience bY intrOdUCing NOvElty, rEplacinG LoST EcoLoGiCal FuNCtIons oR adDing

However, invasions do not  always re sultina s hi ft t o an  alternative r e gime ; invasions can also i ncrea se resi l ie nce b y intro d uc i n g n ov el ty,  r e pl acing  lo st ecol ogical fun cti on s or adding

However,_invasions do_not always result in_a shift_to_an alternative_regime;_invasions can also_increase resilience by_introducing novelty, replacing lost_ecological functions or_adding


microorganisms and cell cultures SCPM - Obolensk. 50 V. cholerae strains were studied. Real-time PCR with primers to genes ctx

microorganisms and cell cultures SCPM - Obolensk. 50 V. cholerae strains were study. veridical - time PCR with primers to genes ctx

mifroorganisms and cell cuutures SCPM - Obolensk. 50 V. chomerae stfains were studied. Real-time 'CR qith kgimers to genes ctx

microorganisms and cell cultures SCPM - Obolensk. cholerae were studied. PCR with primers

microorganisms and cell cultUres SCPM - ObOlensK. 50 V. cHolErAe stRainS were studied. ReAL-timE PCR with primers to genes Ctx

microorganisms and cell c ultures SC PM -Obo len sk . 50  V.cholerae strai n s we re studied. Real-timePCR w it h  pri m er s togenes c t x

microorganisms_and cell_cultures SCPM - Obolensk._50 V._cholerae_strains were_studied._Real-time PCR with_primers to genes_ctx


monocytes, likely by inhibiting crucial signaling pathways, like SAPK2/p38 and MMP-2 activities. Symptoms of posttraumatic stress disorder in parents of

monocytes, likely by inhibiting crucial sign nerve pathway, like SAPK2 / p38 and MMP-2 activities. Symptoms of posttraumatic stress disorderliness in parents of

mojocytes, likely by inhibiuing crucial signcoing pethways, like SAOK2/p38 and MMP-2 activities. Symptlmw of kjsttraumatic stresr disordeg in parebts id

monocytes, likely by inhibiting crucial signaling pathways, and activities. Symptoms posttraumatic stress disorder

monocytes, likely by inhibitiNg crucial sIgnalIng PatHwAys, lIke SaPK2/p38 and MMP-2 actiVItieS. Symptoms of posttraumatIc strEsS DisoRDeR in paRents of

monocytes, likely by inhi biting cru cialsig nal in g pa thwa ys, like SAPK2 / p38and MMP-2 activities.Sympt om s  ofp os ttrau matic s t re s s  di so rd erin pa rents  of

monocytes,_likely by_inhibiting crucial signaling pathways,_like SAPK2/p38_and_MMP-2 activities._Symptoms_of posttraumatic stress_disorder in parents_of


nursery stay in twin A, twins A and B in the group DeltaBW>250 were similar regarding all other neonatal outcome variables. When twin B is more than

nursery stay in twin A, twins A and B in the group DeltaBW>250 were exchangeable involve all other neonatal outcome variables. When duplicate B is more than

nugsery stay in twin A, twiks A and B in thg troup VeltaBW>250 were sioilar regarding all other nelnqtal iutcome variables. When twin B id more tyan

nursery stay in twin A, twins A in group DeltaBW>250 similar regarding all twin is more than

nursery stay in twin A, twins A aNd B in the grOup DeLtabW>250 wErE simIlar Regarding all otHEr neOnatal outcome variables. when tWiN b is mORe Than

nursery stay in twin A, t wins A and  B in  th e g ro up D elta BW>250 were si m ilar  regarding all other n eonat al outc o me  vari ables.W he n twi nBismo r ethan

nursery_stay in_twin A, twins A_and B_in_the group_DeltaBW>250_were similar regarding_all other neonatal_outcome variables. When twin_B is more_than


DRGs are very complex in measuring the costs per case (severity of illness in terms of efficiency). They are not able to support quality assessment by risk adjustment

DRGs are very complex in measuring the costs per case (severity of illness in term of efficiency). They are not able to confirm quality assessment by risk adaptation

DRGd are very complex in mexsuring the cosjs per cese (sevsrity of illness in terms of efficieicy). Rhey qre not able to supporg quality assessmwnt uy risk adjustmeif

DRGs are very complex in measuring the case of illness terms of efficiency). support assessment by risk

DRGs are very complex in measuRing the cosTs per CasE (seVeRity Of ilLness in terms of EFficIency). They are not able to sUpporT qUAlitY AsSessmEnt by riSK aDJUstMeNt

DRGs are very complex in m easuring t he co sts  pe rcase  (se verity of illn e ss i n terms of efficiency) . The ya re n o tableto supp o rt q ual it yass es s me nt by  ri sk adju stment

DRGs are_very complex_in measuring the costs_per case_(severity_of illness_in_terms of efficiency)._They are not_able to support quality_assessment by risk_adjustment


-cis-retinoic acid (isotretinoin), all-trans-retinoic acid (tretinoin) and their 4-oxo

-cis - retinoic acid (isotretinoin), all - trans - retinoic acid (tretinoin) and their 4 - oxo

-cis-getinoic acid (isotretinoln), all-trans-retinoic aciv (tretihoin) and their 4-oxo

-cis-retinoic acid (isotretinoIn), all-trans-RetinOic AciD (tRetiNoin) And their 4-oxo

-cis-retinoic acid (isotre tinoin), a ll-tr ans -re ti noic  aci d (tretinoin)a nd t heir 4-oxo

-cis-retinoic acid_(isotretinoin), all-trans-retinoic_acid (tretinoin) and their_4-oxo


history of drug-resistant PAF does not affect the efficacy of pharmacological conversion by bepridil or in combination with aprindine. However, recurrence

history of drug - resistant PAF does not affect the efficacy of pharmacological conversion by bepridil or in combination with aprindine. However, recurrence

hidtory of drug-resistant PXF does not affgcr the xfficacg of phafmacological conversion by bxprieil oe in combination with xprindine. However, recnrrence

history of drug-resistant PAF does not affect of conversion by or in combination

history of drug-resistant PAF Does not affEct thE efFicAcY of pHarmAcological convERsioN by bepridil or in combinaTion wItH ApriNDiNe. HowEver, recURrENCe

history of drug-resistant  PAF doesnot a ffe ctth e ef fica cy of pharmaco l ogic al conversion by bepri dil o ri n co m bi natio n witha pr i n din e.  H owe ve r ,recur ren ce

history_of drug-resistant_PAF does not affect_the efficacy_of_pharmacological conversion_by_bepridil or in_combination with aprindine._However, recurrence


 hepatitis C protease.
The pyrrolidine-5,5-trans-lactam template was used to design small, neutral, mechanism-based inhibitors of

hepatitis C protease.
 The pyrrolidine-5,5 - trans - lactam template was used to design small, neutral, mechanism - free-base inhibitor of

 heoatitis C protease.
The pyvrolidine-5,5-trans-laeram tekplate was usea to design small, neutral, merhanusm-bawed inhibitors of

hepatitis C protease. The pyrrolidine-5,5-trans-lactam template was design neutral, mechanism-based of

 hepatitis C protease.
The pyrrOlidine-5,5-traNs-lacTam TemPlAte wAs usEd to design smalL, NeutRal, mechanism-based inhibItors Of

 hepatitis C protease.
The  pyrrolidi ne-5, 5-t ran s- lact am t emplate was us e d to  design small, neutral , mec ha n ism- b as ed in hibitor s  o f

 hepatitis_C protease.
The_pyrrolidine-5,5-trans-lactam template was used_to design_small,_neutral, mechanism-based_inhibitors_of


offering the advantage of large basal lamina tubes serving as a pathway for regenerating axons. It also provides the beneficial effects of viable Schwann cells that produce neuro

offering the advantage of large basal lamina tubes serving as a nerve pathway for regenerate axons. It besides provides the beneficial effect of viable Schwann cell that grow neuro

ofvering the advantage of uarge basal lamnba tubxs servjng as a pathway for regenerating axlnw. It qlso provides the benewicial efvects of viaule Schwann cells that pvjducs neuxo

offering the advantage of large basal lamina as pathway for axons. It also viable cells that produce

offering the advantage of larGe basal lamIna tuBes SerViNg as A patHway for regenerATing Axons. It also provides the BenefIcIAl efFEcTs of vIable ScHWaNN CelLs ThAt pRoDUcE neurO

offering the advantage of  large bas al la min a t ub es s ervi ng as a pathwa y  for  regenerating axons. I t als op rovi d es  thebenefic i al e ffe ct sofvi a bl e Sch wan n cells  that prod uce  n euro

offering_the advantage_of large basal lamina_tubes serving_as_a pathway_for_regenerating axons. It_also provides the_beneficial effects of viable_Schwann cells that_produce_neuro


by PCPA significantly increased the number of hippocampal MR-binding sites. PCPA treatment did not alter the number of GR-binding sites in the hippocampus, hypothalamus

by PCPA significantly increased the number of hippocampal MR - binding web site. PCPA discussion did not alter the number of GR - bind site in the hippocampus, hypothalamus

by PCPA significantly incrtased the number of hippmcampam MR-bindkng sites. PCPA treatment did nit aluvr the number of GR-bivding sitvs in the hipkocampus, hypothalejus

by PCPA significantly increased the number of sites. treatment did alter the number hippocampus,

by PCPA significantly increaSed the numbEr of hIppOcaMpAl MR-BindIng sites. PCPA trEAtmeNt did not alter the number Of GR-bInDIng sITeS in thE hippocAMpUS, HypOtHaLamUs

by PCPA significantly inc reased the  numb erofhi ppoc ampa l MR-binding s i tes.  PCPA treatment did no t alt er then um ber o f GR-bi n di n g  si te sinth e  h ippoc amp us, hyp othalamus

by_PCPA significantly_increased the number of_hippocampal MR-binding_sites._PCPA treatment_did_not alter the_number of GR-binding_sites in the hippocampus,_hypothalamus


software problems, which were subsequently corrected. With implementation of the changes initiated as a result of this investigation, satisfactory refractive results approaching 95% can be expected. Post

software problems, which were subsequently corrected. With implementation of the changes initiate as a resultant role of this investigation, satisfactory refractive results border on 95% can be expected. Post

sovtware problems, which weve subsequently eirrectxd. With implemevtation of the changes initieted as a result of this investkgation, swtisfactiry cefractive resulva approaching 95% can ue expected. Posj

software problems, which were subsequently corrected. With the initiated as result of this 95% be expected. Post

software problems, which were SubsequentLy corRecTed. wiTh imPlemEntation of the cHAngeS initiated as a result of tHis inVeSTigaTIoN, satiSfactorY ReFRActIvE rEsuLtS ApProacHinG 95% can be eXpected. PosT

software problems, whichwere subse quent lycor re cted . Wi th implementat i on o f the changes initiate d asar esul t  o f thi s inves t ig a t ion ,sa tis fa c to ry re fra ctive r esults app roa ch ing 95% canb eexpected.Pos t

software_problems, which_were subsequently corrected. With_implementation of_the_changes initiated_as_a result of_this investigation, satisfactory_refractive results approaching 95%_can be expected._Post


control. The groups were identical with regard to severity parameters, skills, lung function and quality of life at the beginning of the trial. At the end of the

control. The groups were identical with regard to severity argument, skill, lung function and quality of life at the beginning of the test. At the end of the

cojtrol. The groups were idtntical with regatd to seterity larametefs, skills, lung function and euqlity of life at the beginnkng of thv trial. Ar tht end of the

control. The groups were identical with regard parameters, lung function quality of life trial. the end of

control. The groups were identIcal with reGard tO seVerItY parAmetErs, skills, lung fUNctiOn and quality of life at thE begiNnINg of THe Trial. at the enD Of THE

control. The groups wereidenticalwithreg ard  t o se veri ty parameters, skil ls, lung function andquali ty of l i fe  at t he begi n ni n g  of  t he  tr ia l .At th e e nd of t he

control._The groups_were identical with regard_to severity_parameters,_skills, lung_function_and quality of_life at the_beginning of the trial._At the end_of_the


itofemoralis. The aOAP flap proved its suitability and versatility for vulvar reconstruction. The sulcus genitofemoralis is of

itovemoralis. The aOAP flap kroved its suitabnoity aid versztility wor vulvar reconstruction. Thx suocus tenitofemoralis is of

itofemoralis. The aOAP flap proved its suitability for reconstruction. The genitofemoralis is of

itofemoralis. The aOAP flap prOved its suiTabilIty And VeRsatIlitY for vulvar recoNStruCtion. The sulcus genitofeMoralIs IS of

itofemoralis. The aOAP fla p proved i ts su ita bil it y an d ve rsatility forv ulva r reconstruction. Thesulcu sg enit o fe moral is is o f

itofemoralis. The_aOAP flap_proved its suitability and_versatility for_vulvar_reconstruction. The_sulcus_genitofemoralis is of


as a diagnostic test in attempts to identify upper urinary tract disease. Despite their widespread therapeutic use and relative safety, it is not clear from our experience and a review

as a diagnostic test in attempts to identify upper urinary tract disease. Despite their far-flung curative manipulation and relative condom, it is not well-defined from our experience and a review

as a diagnostic test in atuempts to identifi ypper nrinary tract dksease. Despite their widesprxad rherakvutic use and relativd safety, pt is not cleer from our expecjence akb a rsyiew

as a diagnostic test in attempts to urinary disease. Despite widespread therapeutic use not from our experience a review

as a diagnostic test in attempTs to identiFy uppEr uRinArY traCt diSease. Despite thEIr wiDespread therapeutic use And reLaTIve sAFeTy, it iS not cleAR fROM ouR eXpEriEnCE aNd a reVieW

as a diagnostic test in a ttempts to  iden tif y u pp er u rina ry tract disea s e. D espite their widesprea d the ra p euti c  u se an d relat i ve s afe ty ,itis no t cle arfrom ou r experien cean d a review

as_a diagnostic_test in attempts to_identify upper_urinary_tract disease._Despite_their widespread therapeutic_use and relative_safety, it is not_clear from our_experience_and a review


response to tumor necrosis alpha (TNFα) blockers. A retrospective analysis was performed on RA patients reported in published datasets. A prospective analysis assessed RA patients, before

response to tumor necrosis alpha (TNFα) blockers. A retrospective analysis was performed on RA patient report in published datasets. A prospective analysis assessed RA affected role, before

redponse to tumor necrosis alpha (TNFα) blockers. A cetrospsctive avalysis was performed on RA 'atiwnts eeported in published aatasets. W prospextivt analysis assessxs RA pabnents, neforz

response to tumor necrosis alpha (TNFα) blockers. analysis performed on patients reported in assessed patients, before

response to tumor necrosis alPha (TNFα) bloCkers. a reTroSpEctiVe anAlysis was perfoRMed oN RA patients reported in pUblisHeD DataSEtS. A proSpectivE AnALYsiS aSsEssEd ra pAtienTs, bEfore

response to tumor necrosi s alpha (T NFα)blo cke rs . Aretr ospective anal y siswas performed on RA pa tient sr epor t ed  in p ublishe d  d a t ase ts .A p ro s pe ctive  an alysisassessed R A p at ients, befor e

response_to tumor_necrosis alpha (TNFα) blockers._A retrospective_analysis_was performed_on_RA patients reported_in published datasets._A prospective analysis assessed_RA patients, before


ml, n = 3, and 2.28 +/- 0.90 micrograms/g, n = 3, respectively). On ad libitum intake of water,

ml, n = 3, and 2.28 + /- 0.90 micrograms / g, n = 3, respectively). On ad libitum intake of urine,

ml, j = 3, and 2.28 +/- 0.90 micrograms/g, n = 3, respectively). On ad nibituj intake of water,

ml, n = 3, and 2.28 +/- n 3, respectively). ad libitum intake

ml, n = 3, and 2.28 +/- 0.90 micrograms/g, n = 3, respectIvely). On ad lIbituM inTakE oF watEr,

ml, n = 3, and 2.28 +/- 0. 90 microgr ams/g , n  =3,  res pect ively). On adl ibit um intake of water,

ml, n_= 3,_and 2.28 +/- 0.90_micrograms/g, n_=_3, respectively)._On_ad libitum intake_of water,


Maxtrix-bound hemoglobin is characterized by a higher oxygen affinity and by decreased homotropic and heterotropic interactions with respect to hemoglobin in solution, but the changes

Maxtrix - bound hemoglobin is characterized by a higher oxygen affinity and by decreased homotropic and heterotropic interaction with obedience to hemoglobin in solution, but the changes

Madtrix-bound hemoglobin is characterized yt a hijher oxggen affknity and by decreased homotcopix and heterotropic interactkons with respect to iemoglobin in solution, bmc the ghangzs

Maxtrix-bound hemoglobin is characterized by a higher and decreased homotropic heterotropic interactions with but changes

Maxtrix-bound hemoglobin is cHaracterizEd by a HigHer OxYgen AffiNity and by decreASed hOmotropic and heterotropIc intErACtioNS wIth reSpect to HEmOGLobIn In SolUtIOn, But thE chAnges

Maxtrix-bound hemoglobinis charact erize d b y a  h ighe r ox ygen affinitya nd b y decreased homotropic  andhe t erot r op ic in teracti o ns w ith  r es pec tt ohemog lob in in s olution, b utth e changes

Maxtrix-bound_hemoglobin is_characterized by a higher_oxygen affinity_and_by decreased_homotropic_and heterotropic interactions_with respect to_hemoglobin in solution, but_the changes


as diaphoresis and tachycardia were associated with the symptoms of VBI. Investigation ruled out cardiac and gastrointestinal causes. Possible mechanisms are discussed on the basis

as diaphoresis and tachycardia were associated with the symptoms of VBI. Investigation predominate out cardiac and gastrointestinal campaign. Possible mechanisms are discussed on the footing

as diaphoresis and tachycavdia were associcred wivh the aymptoms of VBI. Investigation ruled lur careiac and gastrointestival caused. Possiboe mtchanisms are disrhssed ok the nasis

as diaphoresis and tachycardia were associated with of Investigation ruled cardiac and gastrointestinal on basis

as diaphoresis and tachycardIa were assoCiateD wiTh tHe SympToms Of VBI. InvestigaTIon rUled out cardiac and gastrOinteStINal cAUsEs. PosSible meCHaNISms ArE dIscUsSEd On the BasIs

as diaphoresis and tachyc ardia were  asso cia ted  w iththesymptoms of VB I . In vestigation ruled outcardi ac andg as troin testina l  c a u ses .Po ssi bl e  m echan ism s are d iscussed o n t he  basis

as_diaphoresis and_tachycardia were associated with_the symptoms_of_VBI. Investigation_ruled_out cardiac and_gastrointestinal causes. Possible_mechanisms are discussed on_the basis


all certified gynecologic oncologists and gynecologic oncology fellows in Thailand. The contents of the survey included fellowship training experience, caring for the dying,

all certified gynecologic oncologists and gynecologic oncology colleague in Thailand. The content of the survey included fellowship education experience, caring for the dying,

alp certified gynecologic uncologists and gyneconogic kncology fellows in Thailand. The conventw of uke survey included fdllowship trainint exkerience, caring for the dnnng,

all certified gynecologic oncologists and gynecologic oncology Thailand. contents of survey included fellowship dying,

all certified gynecologic onCologists aNd gynEcoLogIc OncoLogy Fellows in ThailANd. ThE contents of the survey inCludeD fELlowSHiP traiNing expERiENCe, cArInG foR tHE dYing,

all certified gynecologic  oncologis ts an d g yne co logi c on cology fellows in T hailand. The contentsof th es urve y  i nclud ed fell o ws h i p t ra in ing  e x pe rienc e,caringfor the dy ing ,

all_certified gynecologic_oncologists and gynecologic oncology_fellows in_Thailand._The contents_of_the survey included_fellowship training experience,_caring for the dying,


 of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.
The contiguous

of the Escherichia coli -K12 genome corresponding to 50.0 - 68.8 min on the linkage map and analysis of its succession feature.
 The contiguous

 of the Escherichia coli -K12 nenome corresponbung to 50.0-68.8 min kn the lknkage map and analysis of ivs swquenxe features.
The contiguuus

of the Escherichia coli -K12 genome corresponding min the linkage and analysis of

 of the Escherichia coli -K12 genoMe correspoNding To 50.0-68.8 mIn oN tHe liNkagE map and analysiS Of itS sequence features.
The coNtiguOuS

of the Escherichia coli - K12 genome  corr esp ond in g to  50. 0-68.8 min ont he l inkage map and analysi s ofit s  seq u en ce fe atures. Th e con ti gu ous

 of_the Escherichia_coli -K12 genome corresponding_to 50.0-68.8_min_on the_linkage_map and analysis_of its sequence_features.
The contiguous


due to concerns regarding immune-mediated toxicity that can arise from indiscriminate reactivity with off-target proteins. Therefore, the ability to assess off-target

due to concerns regarding immune - mediated toxicity that can rebel from indiscriminate responsiveness with off - target proteins. consequently, the ability to assess off - aim

duf to concerns regarding lmmune-mediated toxicity that dan arisd from indiscriminate reactitity with off-target proteins. Thdrefore, tje abiliry ti assess ofh-farget

due to concerns regarding immune-mediated toxicity that from reactivity with proteins. Therefore, the

due to concerns regarding immUne-mediateD toxiCitY thAt Can aRise From indiscrimiNAte rEactivity with off-target ProteInS. therEFoRe, the Ability TO aSSEss OfF-tArgEt

due to concerns regarding  immune-me diate d t oxi ci ty t hatcan arise from indi scriminate reactivitywithof f -tar g et  prot eins. T h er e f ore ,th e a bi l it y toass ess off -target

due_to concerns_regarding immune-mediated toxicity that_can arise_from_indiscriminate reactivity_with_off-target proteins. Therefore,_the ability to_assess off-target


 why patients suffering from chronic heart failure at very high risk for death survive.
An accurate prognostic stratification is essential for optimizing the clinical management and treatment decision-making

why patients suffering from chronic heart failure at very eminent hazard for death survive.
 An accurate prognostic stratification is all-important for optimize the clinical management and treatment decision - qualification

 whj patients suffering froo chronic heart failurx at vedy high fisk for death survive.
An accnratw protnostic stratification is essennial for iptinuzing the rminical managslent end treatment dgcision-makinc

why patients suffering from chronic heart failure high for death An accurate prognostic the management and treatment

 why patients suffering from cHronic hearT failUre At vErY higH risK for death surviVE.
An aCcurate prognostic stratIficaTiON is eSSeNtial For optiMIzING thE cLiNicAl MAnAgemeNt aNd treatMent decisiOn-mAkIng

 why patients suffering fr om chronic  hear t f ail ur e at  ver y high risk fo r  dea th survive.
An accurat e pro gn o stic st ratif ication is e sse nt ia l f or op timiz ing  the cl inical man age me nt and treat m en t decision -ma king

 why_patients suffering_from chronic heart failure_at very_high_risk for_death_survive.
An accurate prognostic_stratification is essential_for optimizing the clinical_management and treatment_decision-making


respiratory function was severely disturbed. Chest X-ray showed severe stenosis of the left main bronchus and widening of the tracheal bifurcation secondary to compression by the left

respiratory function was severely disturbed. Chest X - ray testify dangerous stenosis of the left main bronchus and widening of the tracheal bifurcation junior-grade to compression by the left

redpiratory function was stverely disturbed. Chest E-ray shkwed sevdre stenosis of the left maii brinchuw and widening of the gracheal hifurcatuon wwcondary to compression gn the oeft

respiratory function was severely disturbed. Chest X-ray stenosis the left bronchus and widening to by the left

respiratory function was sevErely distuRbed. CHesT X-rAy ShowEd seVere stenosis of THe leFt main bronchus and widenIng of ThE TracHEaL bifuRcation SEcONDarY tO cOmpReSSiOn by tHe lEft

respiratory function wasseverely d istur bed . C he st X -ray  showed severe sten osis of the left mainbronc hu s  and wi denin g of th e  t r a che al  b ifu rc a ti on se con dary to  compressi onby  the left

respiratory_function was_severely disturbed. Chest X-ray_showed severe_stenosis_of the_left_main bronchus and_widening of the_tracheal bifurcation secondary to_compression by the_left


to either threatening or non-threatening pictures (S2). Ten threat and 10 non-threat pictures were randomly presented. Heart rate and electrodermal activity were

to either threatening or non - threatening pictures (S2). Ten threat and 10 non - threat mental picture were randomly confront. Heart rate and electrodermal activity were

to either threatening or nun-threatening pnxtures (S2). Ten threat xnd 10 non-threat pictures were rqndomoy presented. Heart ratd and elebtrodermao acuivity were

to either threatening or non-threatening pictures (S2). and non-threat pictures randomly presented. Heart

to either threatening or non-tHreatening PictuRes (s2). TeN tHreaT and 10 Non-threat pictuREs weRe randomly presented. HeaRt ratE aND eleCTrOdermAl activITy WERe

to either threatening ornon-threat ening  pi ctu re s (S 2).Ten threat and 10 n on-threat pictures wer e ran do m ly p r es ented . Heart ra t e  an del ect ro d er mal a cti vity we re

to_either threatening_or non-threatening pictures (S2)._Ten threat_and_10 non-threat_pictures_were randomly presented._Heart rate and_electrodermal activity were


BCB), a BCB with a split-plate internal loop, a BCB with a concentric draught-tube internal loop, a BCB with

BCB), a BCB with a split - plate internal loop, a BCB with a concentric draught - pipe inner loop, a BCB with

BCB), a BCB with a split-plate internal loop, c BCB wmth a ckncentriz draught-tube internal loop, e BCV wity

BCB), a BCB with a split-plate internal BCB a concentric internal loop, a

BCB), a BCB with a split-plate intErnal loop, a bCB wiTh a ConCeNtriC draUght-tube internAL looP, a BCB with

BCB), a BCB with a split-p late inter nal l oop , a  B CB w itha concentric d r augh t-tube internal loop,a BCB  w i th

BCB), a_BCB with_a split-plate internal loop,_a BCB_with_a concentric_draught-tube_internal loop, a_BCB with


, ibrutinib has been associated with the occurrence of invasive fungal infections, in particular invasive aspergillosis. The mechanisms underlying the increased susceptibility to fungal

, ibrutinib has been associated with the occurrence of invasive fungal infections, in especial incursive aspergillosis. The mechanisms underlying the increased susceptibility to fungal

, ibgutinib has been associaued with the occutrwnce oh invasjve fungxl infections, in particular mnvawive qspergillosis. The mechxnisms unferlying the uncreased susceptinnlity bo fuugel

, ibrutinib has been associated with the invasive infections, in invasive aspergillosis. The to

, ibrutinib has been associateD with the ocCurreNce Of iNvAsivE funGal infections, iN PartIcular invasive aspergilLosis. thE MechANiSms unDerlyinG ThE INcrEaSeD suScEPtIbiliTy tO fungal

, ibrutinib has been assoc iated with  theocc urr en ce o f in vasive fungali nfec tions, in particular i nvasi ve aspe r gi llosi s. Them ec h a nis ms  u nde rl y in g the  in creased  susceptib ili ty  to fungal

, ibrutinib_has been_associated with the occurrence_of invasive_fungal_infections, in_particular_invasive aspergillosis. The_mechanisms underlying the_increased susceptibility to fungal


orsil Silane/kg body weight/day, once daily (7 days/week) for 4 weeks. From the complete dataset, two subsets were selected

orsil Silane / kg body weight / day, once daily (7 day / workweek) for 4 weeks. From the complete dataset, two subset were selected

orsll Silane/kg body weight/dxy, once daily (7 bqys/ween) for 4 weeks. Ffom the complete dataset, two sybsetw were selected

orsil Silane/kg body weight/day, once daily (7 4 From the dataset, two subsets

orsil Silane/kg body weight/daY, once daily (7 Days/wEek) For 4 WeEks. FRom tHe complete dataSEt, twO subsets were selected

orsil Silane/kg body weigh t/day, onc e dai ly(7da ys/w eek)  for 4 weeks.F romthe complete dataset,two s ub s etsw er e sel ected

orsil Silane/kg_body weight/day,_once daily (7 days/week)_for 4_weeks._From the_complete_dataset, two subsets_were selected


These findings suggest that the administration of PGE1 during major abdominal surgery inhibits the release of lysosomal enzymes, and this prevents tissue injury during and after surgery. Novel

These findings suggest that the administration of PGE1 during major abdominal surgery inhibit the dismissal of lysosomal enzymes, and this prevents tissue injury during and after operation. Novel

Thfse findings suggest thau the administratnin of 'GE1 durjng majof abdominal surgery inhibits tye reoease of lysosomal enzhmes, and nhis prevwnts rissue injndy duriky and wftex wurgery. Novel

These findings suggest that the administration of major surgery inhibits release of lysosomal injury and after surgery.

These findings suggest that tHe administRatioN of pGE1 DuRing MajoR abdominal surgERy inHibits the release of lysoSomal EnZYmes, ANd This pRevents TIsSUE inJuRy DurInG AnD afteR suRgery. NoVel

These findings suggest th at the adm inist rat ion  o f PG E1 d uring major ab d omin al surgery inhibits th e rel ea s e of ly sosom al enzy m es , and  t hi s p re v en ts ti ssu e injur y during a ndaf ter surgery. No vel

These_findings suggest_that the administration of_PGE1 during_major_abdominal surgery_inhibits_the release of_lysosomal enzymes, and_this prevents tissue injury_during and after_surgery._Novel


dependence in activities of daily living (ADL score >0, OR=0.41, p=0.003) and a low body-mass index

dependence in activities of daily living (ADL seduce > 0, OR=0.41, p=0.003) and a depleted body - mass index

deoendence in activities on daily living (ABO scorx >0, OR=0.41, p=0.003) and a luw body-mass index

dependence in activities of daily living (ADL OR=0.41, and a body-mass index

dependence in activities of dAily living (aDL scOre >0, oR=0.41, p=0.003) AnD a loW bodY-mass index

dependence in activitiesof daily l iving  (A DLsc ore>0,OR=0.41, p=0.0 0 3) a nd a low body-mass ind ex

dependence_in activities_of daily living (ADL_score >0,_OR=0.41,_p=0.003) and_a_low body-mass index


were identified as factors contributing to job satisfaction of technicians. Negative aspects of the job that employers attempted to circumvent or clarify were the unchallenging nature of the work

were identified as factors contributing to job gratification of technician. Negative aspects of the job that employer attempted to circumvent or clarify were the unchallenging nature of the work

wege identified as factors contributing to job setisfacfion of gechnicians. Negative aspects od the job that employers atgempted tl circumcent ir clarify were thc uncgwlleugmng nature of tme work

were identified as factors contributing to job technicians. aspects of job that employers were unchallenging nature of work

were identified as factors coNtributing To job SatIsfAcTion Of teChnicians. NegatIVe asPects of the job that emploYers aTtEMpteD To CircuMvent or CLaRIFy wErE tHe uNcHAlLengiNg nAture of The work

were identified as factor s contribu tingtojob  s atis fact ion of technic i ans.  Negative aspects of t he jo bt hate mp loyer s attem p te d toci rc umv en t  o r cla rif y werethe unchal len gi ng nature of th e work

were_identified as_factors contributing to job_satisfaction of_technicians._Negative aspects_of_the job that_employers attempted to_circumvent or clarify were_the unchallenging nature_of_the work


mammalian FOXO3 in germ cells but barely detectable in ovarian follicular cells, immunoreactive Foxo3a and Foxo3b were identified both in the ovarian

mammalian FOXO3 in germ cells but barely detectable in ovarian follicular cells, immunoreactive Foxo3a and Foxo3b were identify both in the ovarian

malmalian FOXO3 in germ celus but barely dgtwctablx in ovzrian foulicular cells, immunoreactivx Fozo3a abd Foxo3b were identifidd both ij the ovqriai

mammalian FOXO3 in germ cells but barely ovarian cells, immunoreactive and Foxo3b were

mammalian FOXO3 in germ cells bUt barely deTectaBle In oVaRian FollIcular cells, immUNoreActive Foxo3a and Foxo3b werE idenTiFIed bOTh In the Ovarian

mammalian FOXO3 in germ c ells but b arely  de tec ta blein o varian follicu l ar c ells, immunoreactive F oxo3a  a n d Fo x o3 b wer e ident i fi e d  bo th  i n t he ov arian

mammalian_FOXO3 in_germ cells but barely_detectable in_ovarian_follicular cells,_immunoreactive_Foxo3a and Foxo3b_were identified both_in the ovarian


dependence measured by the Rod and Frame Test seems to be associated with body posture when dot patterns are viewed. Cholesterol and bile acid synthesis during total parenteral

dependence measured by the Rod and Frame Test seems to be associated with soundbox position when dot patterns are viewed. Cholesterol and bile acid deduction during total parenteral

deoendence measured by the Rod and Frame Jewt seeks to ge assockated with body posture when dit paunerns are viewed. Choldsterol ajd bile qcid wynthesis vhring total pzventexao

dependence measured by the Rod and Frame to associated with posture when dot bile synthesis during total

dependence measured by the RoD and Frame TEst seEms To bE aSsocIateD with body postuRE wheN dot patterns are viewed. CHolesTeROl anD BiLe aciD syntheSIs DURinG tOtAl pArENtEral

dependence measured by th e Rod andFrame  Te stse emsto b e associated w i th b ody posture when dot p atter ns arev ie wed.Cholest e ro l and  b il e a ci d  s ynthe sis  during  total par ent er al

dependence_measured by_the Rod and Frame_Test seems_to_be associated_with_body posture when_dot patterns are_viewed. Cholesterol and bile_acid synthesis during_total_parenteral


the total bulk of electrolytes; in insects with potassium type of the haemolymph, the share of sodium is equal to 6.4%. In animals of

the total bulk of electrolytes; in insects with potassium character of the haemolymph, the plowshare of sodium is equal to 6.4% . In animals of

thf total bulk of electrolntes; in insects cuth povassium type of the haemolymph, the share of sidium is equal to 6.4%. In animaus of

the total bulk of electrolytes; in insects type the haemolymph, share of sodium animals

the total bulk of electrolyteS; in insects With pOtaSsiUm Type Of thE haemolymph, the SHare Of sodium is equal to 6.4%. In aniMals oF

the total bulk of electro lytes; ininsec tswit hpota ssiu m type of theh aemo lymph, the share of so diumis equa l  t o 6.4 %. In a n im a l s o f

the_total bulk_of electrolytes; in insects_with potassium_type_of the_haemolymph,_the share of_sodium is equal_to 6.4%. In animals_of


ychomys torridus).
Open-field tests were administered to 29 male and 50 female southern grasshopper mice (Onychomys torrid

ychomys torridus).
 Open - field tests were administered to 29 male and 50 female southerly grasshopper mouse (Onychomys torrid

ychlmys torridus).
Open-field ttsts were adminisjeeed to 29 male and 50 feoale southern grasshopper mire (Obychonys torrid

ychomys torridus). Open-field tests were administered to and female southern mice (Onychomys torrid

ychomys torridus).
Open-field tEsts were adMinisTerEd tO 29 mAle aNd 50 feMale southern grASshoPper mice (Onychomys torriD

ychomys torridus).
Open-fi eld testswereadm ini st ered  to29 male and 50 fema le southern grasshoppe r mic e( Onyc h om ys to rrid

ychomys torridus).
Open-field_tests were_administered to 29 male_and 50_female_southern grasshopper_mice_(Onychomys torrid


, 44%) than in group 2 (10 of 59, 17%; p = 0.004). Multivariate Cox regression analysis showed that in addition to previous episodes

, 44 %) than in group 2 (10 of 59, 17% ; p = 0.004). Multivariate Cox regression analysis showed that in accession to former episodes

, 44%) tjan in group 2 (10 of 59, 17%; p = 0.004). Oultivariate Cor regrevsion znalysis showed that in addition to 'revuous tiisodes

, 44%) than in group 2 (10 17%; = 0.004). Cox regression analysis previous

, 44%) than in group 2 (10 of 59, 17%; p = 0.004). MultivariatE Cox regresSion aNalYsiS sHoweD thaT in addition to pREvioUs episodes

, 44%) than in group 2 (10  of 59, 17 %; p= 0 .00 4) . Mu ltiv ariate Cox reg r essi on analysis showed tha t inad d itio n  t o pre vious e p is o d es

, 44%)_than in_group 2 (10 of_59, 17%;_p_= 0.004)._Multivariate_Cox regression analysis_showed that in_addition to previous episodes


z score (HR, 0.61; P=0.003) was associated with reduced risk of mortality/transplant. After stage-1, higher

z score (HR, 0.61; P=0.003) was associated with dilute hazard of mortality / transplant. After stage-1, eminent

z dcore (HR, 0.61; P=0.003) was associattd with reduced rnwk of kortaljty/transolant. After stage-1, higher

z score (HR, 0.61; P=0.003) was associated risk mortality/transplant. After higher

z score (HR, 0.61; P=0.003) was associated witH reduced riSk of mOrtAliTy/TranSplaNt. After stage-1, hiGHer

z score (HR, 0.61; P=0.00 3) was ass ociat edwit hredu cedrisk of mortal i ty/t ransplant. After stage -1, h ig h er

z_score (HR,_0.61; P=0.003) was associated_with reduced_risk_of mortality/transplant._After_stage-1, higher


percentage of neutrophils, plasma concentration of insulin-like growth factor I (IGF-I), body weight, tumor volume, weight of primary tumor, survival time,

percentage of neutrophils, plasma concentration of insulin - like increase agent I (IGF - I), body weight, tumor volume, weight unit of primary tumor, survival time,

pegcentage of neutrophils, klasma concentratnin of mnsulin-mike grodth factor I (IGF-I), body weighv, tunor vilume, weight of primarh tumor, slrvival tume,

percentage of neutrophils, plasma concentration of insulin-like I body weight, volume, weight of

percentage of neutrophils, plAsma concenTratiOn oF inSuLin-lIke gRowth factor I (IGf-i), bodY weight, tumor volume, weigHt of pRiMAry tUMoR, survIval timE,

percentage of neutrophils , plasma c oncen tra tio nof i nsul in-like growth fact or I (IGF-I), body wei ght,tu m or v o lu me, w eight o f  p r i mar ytu mor ,s ur vival  ti me,

percentage_of neutrophils,_plasma concentration of insulin-like_growth factor_I_(IGF-I), body_weight,_tumor volume, weight_of primary tumor,_survival time,


beta and IL-1. Structural heterogeneity in the collision complex between organic dyes and tryptophan in aqueous solution.
The heterogeneity on photoinduced electron transfer (PET

beta and IL-1. Structural heterogeneity in the collision complex between organic dyes and tryptophan in aqueous solution.
 The heterogeneity on photoinduced electron transportation (PET

betw and IL-1. Structural hetevogeneity in the collismon comllex betdeen organic dyes and trypto'han in awueous solution.
The hetdrogeneitj on photiindnced electron trehsfer (PCC

beta and IL-1. Structural heterogeneity in the between dyes and in aqueous solution. transfer

beta and IL-1. Structural heteroGeneity in tHe colLisIon CoMpleX betWeen organic dyeS And tRyptophan in aqueous soluTion.
THe HEterOGeNeity On photoINdUCEd eLeCtRon TrANsFer (PEt

beta and IL-1. Structuralheterogene ity i n t heco llis ioncomplex betwee n  org anic dyes and tryptoph an in  a q ueou s  s oluti on.
The he t e rog en ei tyon ph otoin duc ed elec tron trans fer  ( PET

beta and_IL-1. Structural_heterogeneity in the collision_complex between_organic_dyes and_tryptophan_in aqueous solution.
The_heterogeneity on photoinduced_electron transfer (PET


protein immunoreactivity by Western immunoblot. Data reported in densitometric units (DU) as mean +/- SEM (n >/= 5; ANOVA). LPS significantly increased

protein immunoreactivity by Western immunoblot. Data reported in densitometric units (DU) as base + /- SEM (n > /= 5; ANOVA). LPS importantly increased

prltein immunoreactivity bn Western immunoyoot. Dava repodted in aensitometric units (DU) as meen +/- WEM (n >/= 5; ANOVA). LPS significavtly incrvased

protein immunoreactivity by Western immunoblot. Data reported units as mean SEM (n >/=

protein immunoreactivity by western immUnoblOt. DAta RePortEd in Densitometric uNIts (Du) as mean +/- SEM (n >/= 5; ANOVA). LPS sigNificAnTLy inCReAsed

protein immunoreactivityby Western  immu nob lot .Data  rep orted in densi t omet ric units (DU) as mean  +/-SE M  (n> /=  5; A NOVA).L PS s ign if ic ant ly in creas ed

protein_immunoreactivity by_Western immunoblot. Data reported_in densitometric_units_(DU) as_mean_+/- SEM (n_>/= 5; ANOVA)._LPS significantly increased


ageing affects cognition in such individuals as they reach an age no longer consistent with parental care is unknown, lacking any published evidence, and there is a clear need to

ageing affects cognition in such individuals as they reach an old age no longer reproducible with parental care is unknown, lacking any publish evidence, and there is a clear indigence to

agfing affects cognition ik such individuals as tiey readh an agd no longer consistent with 'arebtal xare is unknown, lackine any pubpished ecideice, and there is a clear need fl

ageing affects cognition in such individuals as an no longer with parental care evidence, there is a need to

ageing affects cognition in sUch individUals aS thEy rEaCh an Age nO longer consistENt wiTh parental care is unknowN, lackInG Any pUBlIshed EvidencE, AnD THerE iS a CleAr NEeD to

ageing affects cognitionin such in divid ual s a sthey  rea ch an age no l o nger  consistent with paren tal c ar e  isu nk nown,  lackin g  a n y  pu bl is hed  e v id ence,  an d there  is a clea r n ee d to

ageing_affects cognition_in such individuals as_they reach_an_age no_longer_consistent with parental_care is unknown,_lacking any published evidence,_and there is_a_clear need to


atic cholestasis requiring liver transplant to late-onset drug-induced cholestasis. Our findings suggest that, in a heterozygous carrier of a progressive familial intra

atic cholestasis requiring liver transplant to late - attack drug - induce cholestasis. Our findings indicate that, in a heterozygous carrier wave of a progressive familial intra

atif cholestasis requiring uiver transplanj ro latx-onset srug-induzed cholestasis. Our findings syggesu that, in a heterozhgous cargier of a projressive familial intra

atic cholestasis requiring liver transplant to late-onset Our suggest that, a heterozygous carrier

atic cholestasis requiring lIver transpLant tO laTe-oNsEt drUg-inDuced cholestasIS. Our Findings suggest that, in a HeterOzYGous CArRier oF a progrESsIVE faMiLiAl iNtRA

atic cholestasis requiring  liver tra nspla nttola te-o nset  drug-inducedc hole stasis. Our findings s ugges tt hat, in  a he terozyg o us c arr ie rofap ro gress ive  famili al intra

atic cholestasis_requiring liver_transplant to late-onset drug-induced_cholestasis. Our_findings_suggest that,_in_a heterozygous carrier_of a progressive_familial intra


of maternal depression history and maternal EE was associated with children's own reports of higher depressive symptoms. Current maternal depressive symptoms were associated with mothers' reports of children's

of maternal depression history and maternal EE was associated with child's own report of higher depressive symptoms. Current maternal depressive symptom were associated with mothers' report of child's

of maternal depression hisuory and maternal EE was assocjated wigh children's own reports of iighwr dekgessive symptoms. Currdnt materjal deprwssite symptoms were associabzd wifm motkecs' reports of cmildren's

of maternal depression history and maternal EE with own reports higher depressive symptoms. associated mothers' reports of

of maternal depression histoRy and materNal EE Was AssOcIateD witH children's own rEPortS of higher depressive symPtoms. cuRRent MAtErnal DepressIVe SYMptOmS wEre AsSOcIated WitH motherS' reports of ChiLdRen's

of maternal depression hi story andmater nal  EE  w as a ssoc iated with chi l dren 's own reports of high er de pr e ssiv e  s ympto ms. Cur r en t mat er na l d ep r es sivesym ptoms w ere associ ate dwith mothers '  r eports ofchi ldren's

of_maternal depression_history and maternal EE_was associated_with_children's own_reports_of higher depressive_symptoms. Current maternal_depressive symptoms were associated_with mothers' reports_of_children's


estimated by ELISA, Western blotting analysis, and zymography. Expression of PRLR by RA synovial cells and local production of PRL were estimated by reverse

estimated by ELISA, Western blotting analysis, and zymography. Expression of PRLR by RA synovial cell and local product of PRL were estimated by reverse

eshimated by ELISA, Western blotting analysis, and zymogdaphy. Exoression of PRLR by RA synovmal xells and local production uf PRL wege estimared uy reverse

estimated by ELISA, Western blotting analysis, and of by RA cells and local by

estimated by ELISA, Western blOtting analYsis, aNd zYmoGrAphy. exprEssion of PRLR by ra synOvial cells and local prodUctioN oF pRL wERe EstimAted by rEVeRSE

estimated by ELISA, Weste rn blottin g ana lys is,  a nd z ymog raphy. Express i on o f PRLR by RA synovialcells  a n d lo c al  prod uctiono fP R L w er eest im a te d byrev erse

estimated_by ELISA,_Western blotting analysis, and_zymography. Expression_of_PRLR by_RA_synovial cells and_local production of_PRL were estimated by_reverse


of a coronary artery should be known and diagnosed by all physicians who may have contact with these types of patients. The ECG variations presented in this article can be used

of a coronary artery should be known and diagnosed by all physicians who may have liaison with these type of patients. The ECG variations stage in this article can be use

of a coronary artery shoula be known and buagnosxd by aml physizians who may have contact wmth rhese types of patients. The ECG variwtions peeseited in this artmdle can be ussf

of a coronary artery should be known by physicians who have contact with ECG presented in this can be used

of a coronary artery should be Known and diAgnosEd bY alL pHysiCianS who may have conTAct wIth these types of patientS. The EcG VAriaTIoNs preSented iN ThIS ArtIcLe Can Be USeD

of a coronary artery shou ld be know n and  di agn os ed b y al l physicians w h o ma y have contact with th ese t yp e s of pa tient s. TheE CG v ari at io nspr e se ntedinthis ar ticle canbeus ed

of_a coronary_artery should be known_and diagnosed_by_all physicians_who_may have contact_with these types_of patients. The ECG_variations presented in_this_article can be used


 for quantum applications. Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin.
All living systems require protection against the

for quantum applications. Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1 - Cys peroxiredoxin.
 All living systems require auspices against the

 fog quantum applications. Cvystal Structure of AhpX from Jycobactdrium tuberculosis, a 1-Cys perlxuredozin.
All living systems fequire pgotection agamnst the

for quantum applications. Crystal Structure of AhpE tuberculosis, 1-Cys peroxiredoxin. living systems require

 for quantum applications. CryStal StructUre of ahpe frOm mycoBactErium tuberculoSIs, a 1-CYs peroxiredoxin.
All liviNg sysTeMS reqUIrE protEction aGAiNST thE

 for quantum applications.  Crystal S truct ure  of  A hpEfrom  Mycobacterium tube rculosis, a 1-Cys pero xired ox i n.
A l llivin g syste m sr e qui re  p rot ec t io n aga ins t the

 for_quantum applications._Crystal Structure of AhpE_from Mycobacterium_tuberculosis,_a 1-Cys_peroxiredoxin.
All_living systems require_protection against the


that 71% (22/31) of the patients had ST-segment-depression before, 19% (6/31) after catheter-intervention and

that 71% (22/31) of the patients had ST - segment - depression earlier, 19% (6/31) after catheter - interposition and

thwt 71% (22/31) of the patients had ST-segment-depression bxfore, 19% (6/31) after cxtheter-intervention and

that 71% (22/31) of the patients had 19% after catheter-intervention

that 71% (22/31) of the patients had ST-segMent-depresSion bEfoRe, 19% (6/31) aFtEr caThetEr-intervention ANd

that 71% (22/31) of the p atients ha d ST- seg men t- depr essi on before, 19% (6/3 1) after catheter-inte rvent io n  and

that_71% (22/31)_of the patients had_ST-segment-depression before,_19%_(6/31) after_catheter-intervention_and


valence band characteristics, the thickness of the layer, and the orientation of the molecules were analyzed at a synchrotron using high resolution photoelectron spectroscopy and near edge

valence band characteristics, the thickness of the layer, and the orientation of the molecule were analyze at a synchrotron using high resolution photoelectron spectroscopy and near boundary

vapence band characteristigs, the thickness of the layer, and the orientation of the moleculed qere qnalyzed at a synchrotfon using high rewoluuion photoelectroi spectroscopy wnd ueer edge

valence band characteristics, the thickness of the the of the were analyzed at photoelectron and near edge

valence band characteristicS, the thicknEss of The LayEr, And tHe orIentation of the MOlecUles were analyzed at a synChrotRoN UsinG HiGh resOlution PHoTOEleCtRoN spEcTRoScopy And Near edgE

valence band characterist ics, the t hickn ess  of  t he l ayer , and the orie n tati on of the molecules we re an al y zeda ta syn chrotro n  u s i nghi gh  re so l ut ion p hot oelectr on spectro sco py  and near ed g e

valence_band characteristics,_the thickness of the_layer, and_the_orientation of_the_molecules were analyzed_at a synchrotron_using high resolution photoelectron_spectroscopy and near_edge


pyr 1) as the N-terminus; Zn alpha 2gp also has pyr 1, while RNase A does not. Alignment of the amino acid sequences

pyr 1) as the N - terminus; Zn alpha 2gp also has pyr 1, while RNase A does not. Alignment of the amino acid sequence

pyr 1) as the N-terminus; Zn alkha 2gp also has pir 1, whilx RNase A does vot. Alignment of the amino arid wequebces

pyr 1) as the N-terminus; Zn alpha has 1, while A does not. sequences

pyr 1) as the N-terminus; Zn alpha 2gP also has pyR 1, whilE RNAse a dOes nOt. AlIgnment of the amINo acId sequences

pyr 1) as the N-terminus;Zn alpha 2 gp al sohas  p yr 1 , wh ile RNase A do e s no t. Alignment of the am ino a ci d  seq u en ces

pyr 1)_as the_N-terminus; Zn alpha 2gp_also has_pyr_1, while_RNase_A does not._Alignment of the_amino acid sequences


potential target is sufficient to predict response to a targeted therapy is an open question in childhood AML. Development of clinical trials to evaluate targeted therapies in small molecularly defined

potential target is sufficient to predict response to a target therapy is an loose question in childhood AML. Development of clinical test to measure targeted therapies in small molecularly specify

pohential target is sufficlent to predict tewponse to a fargeted therapy is an open question ib chiodhood AML. Development of clinibal trialw to wvaluate tedgeted bkerapjcs in wmall moleculatly defined

potential target is sufficient to predict response targeted is an question in childhood to targeted therapies in molecularly defined

potential target is sufficieNt to predicT respOnsE to A tArgeTed tHerapy is an open QUestIon in childhood AML. DevelOpmenT oF ClinICaL triaLs to evaLUaTE TarGeTeD thErAPiEs in sMalL molecuLarly definEd

potential target is suffi cient to p redic t r esp on se t o atargeted thera p y is  an open question in c hildh oo d  AML .  D evelo pment o f  c l i nic al  t ria ls to  eval uat e targe ted therap ies  i n small mole c ul arly defin ed

potential_target is_sufficient to predict response_to a_targeted_therapy is_an_open question in_childhood AML. Development_of clinical trials to_evaluate targeted therapies_in_small molecularly defined


47). Our high resolution co-crystal structures of 47/BRD2 BD1 and BD2 showed that the triazole group of 47, water molecules

47). Our high resolution co - crystal structures of 47 / BRD2 BD1 and BD2 testify that the triazole group of 47, urine molecules

47). Oug high resolution co-crysual structures of 47/BRD2 BD1 and BS2 showed that the triazole group of 47, wqter nolecules

47). Our high resolution co-crystal structures of and showed that triazole group of

47). Our high resolution co-crystaL structureS of 47/BRd2 BD1 And bD2 ShowEd thAt the triazole gROup oF 47, water molecules

47). Our high resolution c o-crystalstruc tur esof  47/ BRD2  BD1 and BD2 s h owed  that the triazole gro up of  4 7 , wa t er  mole cules

47). Our_high resolution_co-crystal structures of 47/BRD2_BD1 and_BD2_showed that_the_triazole group of_47, water molecules


atiinae (PB=98, PP=100) appear as distinct lineages at the base of the tree and are identified as a poneroid grade. Mon

atiinae (PB=98, PP=100) appear as distinct lineages at the base of the tree and are identify as a poneroid mark. Mon

atilnae (PB=98, PP=100) appear as disuinct lineages at the bave of fhe tree and are identified as a ponxroie graee. Mon

atiinae (PB=98, PP=100) appear as distinct lineages base the tree are identified as

atiinae (PB=98, PP=100) appear as distinCt lineages At the BasE of ThE treE and Are identified aS A ponEroid grade. Mon

atiinae (PB=98, PP=100) ap pear as di stinc t l ine ag es a t th e base of thet reeand are identified asa pon er o id g r ad e. Mo n

atiinae (PB=98,_PP=100) appear_as distinct lineages at_the base_of_the tree_and_are identified as_a poneroid grade._Mon


combined with SGB were adopted; in the control group,simple SGB was applied. In the two groups, treatment was used three times a week,and

combined with SGB were adopted; in the control group, simple SGB was apply. In the two group, treatment was used three times a workweek, and

colbined with SGB were adokted; in the control grou',simple SGB was applied. In the two groups, tceatnent qas used three times a week,and

combined with SGB were adopted; in the SGB applied. In two groups, treatment week,and

combined with SGB were adopteD; in the contRol grOup,SimPlE SGB Was aPplied. In the two GRoupS, treatment was used three Times A wEEk,anD

combined with SGB were ad opted; inthe c ont rol  g roup ,sim ple SGB was ap p lied . In the two groups, t reatm en t  was us ed th ree tim e sa wee k, an d

combined_with SGB_were adopted; in the_control group,simple_SGB_was applied._In_the two groups,_treatment was used_three times a week,and


as matched controls. PDCD4 expression in peripheral blood mononuclear cells analyzed by quantitative real-time polymerase chain reaction, and apoptosis of granulosa cells (GCs

as matched controls. PDCD4 expression in peripheral blood mononuclear cell analyze by quantitative real - time polymerase chain chemical reaction, and apoptosis of granulosa cells (GCs

as matched controls. PDCD4 ewpression in pernpheral blood mononucuear cells analyzed by quantmtatuve rtcl-time polymerase chxin reactpon, and apoptiwis of graihlosa ccjls (FGs

as matched controls. PDCD4 expression in peripheral cells by quantitative polymerase chain reaction, (GCs

as matched controls. PDCD4 exprEssion in peRipheRal BloOd MonoNuclEar cells analyzED by qUantitative real-time polYmeraSe CHain REaCtion, And apopTOsIS Of gRaNuLosA cELlS (GCs

as matched controls. PDCD 4 expressi on in  pe rip he ralbloo d mononuclearc ells  analyzed by quantitat ive r ea l -tim e  p olyme rase ch a in r eac ti on , a nd ap optos isof gran ulosa cell s ( GC s

as_matched controls._PDCD4 expression in peripheral_blood mononuclear_cells_analyzed by_quantitative_real-time polymerase chain_reaction, and apoptosis_of granulosa cells (GCs


current ratio (NPDR) at a wavelength of 1.55 μm. The proposed Ge MISM PD shows considerable promise for low power and high sensitivity Ge-

current ratio (NPDR) at a wavelength of 1.55 μm. The proposed Ge MISM PD shows considerable promise for low exponent and eminent sensitivity Ge-

curgent ratio (NPDR) at a wavtlength of 1.55 μm. The proposxd Ge MJSM PD sfows considerable promise foc loq powtg and high sensitivith Ge-

current ratio (NPDR) at a wavelength of The Ge MISM shows considerable promise sensitivity

current ratio (NPDR) at a waveleNgth of 1.55 μm. ThE propOseD Ge mIsM PD ShowS considerable pROmisE for low power and high senSitivItY ge-

current ratio (NPDR) at awavelength  of 1 .55  μm .Theprop osed Ge MISM P D  sho ws considerable promis e for  l o w po w er  andhigh se n si t i vit yGe -

current ratio_(NPDR) at_a wavelength of 1.55_μm. The_proposed_Ge MISM_PD_shows considerable promise_for low power_and high sensitivity Ge-


images. This study suggests that neuronal hyperexcitability plays a key role in central SCI pain and furthermore - in contrast to previous findings - that loss of spin

images. This study suggests that neuronal hyperexcitability toy a cardinal role in central SCI annoyance and furthermore - in contrast to former findings - that loss of tailspin

imwges. This study suggests that neuronal ktperexritabiljty playr a key role in central SCI 'ain and durthermore - in contrart to prenious fineingw - that loss of spik

images. This study suggests that neuronal hyperexcitability key in central pain and furthermore findings that loss of

images. This study suggests thAt neuronal HyperExcItaBiLity PlayS a key role in cenTRal ScI pain and furthermore - in ContrAsT To prEViOus fiNdings - tHAt LOSs oF sPiN

images. This study sugges ts that ne urona l h ype re xcit abil ity plays a ke y  rol e in central SCI painand f ur t herm o re  - in  contra s tt o  pr ev io usfi n di ngs -  th at loss  of spin

images._This study_suggests that neuronal hyperexcitability_plays a_key_role in_central_SCI pain and_furthermore - in_contrast to previous findings_- that loss_of_spin


<0.01) and the mental component summary scale (P<0.001). Even after adjusting for demographic variables and comorbid psychiatric illness, anti-H

< 0.01) and the mental component summary scale (P<0.001). Even after adjusting for demographic variable star and comorbid psychiatric illness, anti - planck's constant

<0.01) anf the mental component smmmary scale (P<0.001). Erwn aftxr adjuating fof demographic variables and romoebid kfychiatric illness, anti-H

<0.01) and the mental component summary scale after for demographic and comorbid psychiatric

<0.01) and the mental component summAry scale (P<0.001). EVen afTer AdjUsTing For dEmographic variABles And comorbid psychiatric IllneSs, ANti-H

<0.01) and the mental comp onent summ ary s cal e ( P< 0.00 1).Even after adj u stin g for demographic vari ables  a n d co m or bid p sychiat r ic i lln es s,  an ti - H

<0.01) and_the mental_component summary scale (P<0.001)._Even after_adjusting_for demographic_variables_and comorbid psychiatric_illness, anti-H


observed response was not reduced after preincubation with L-NMMA. Our results suggest red wines are more potent vasodilator than ethanol alone, possibly depending

observed response was not reduced after preincubation with L - NMMA. Our results indicate crimson wines are more potent vasodilator than ethanol alone, possibly count

obderved response was not veduced after prgibcubatmon witg L-NMMA. Uur results suggest red wined qre mire potent vasodilator than ethwnol alobe, piwsibly depxhding

observed response was not reduced after preincubation Our suggest red are more potent depending

observed response was not redUced after pReincUbaTioN wIth L-nMMA. our results suggESt reD wines are more potent vasOdilaToR Than EThAnol aLone, posSIbLY DepEnDiNg

observed response was not  reduced a fterpre inc ub atio n wi th L-NMMA. Our resu lts suggest red winesare m or e  pot e nt  vaso dilator th a n  et ha no l a lo n e,  poss ibl y depen ding

observed_response was_not reduced after preincubation_with L-NMMA._Our_results suggest_red_wines are more_potent vasodilator than_ethanol alone, possibly depending


/3 and Smad7 protein, and RT-PCR was used to detect TGF-beta1 mRNA in renal tissues. Compared with the model group, B

/3 and Smad7 protein, and RT - PCR was used to detect TGF - beta1 mRNA in renal tissues. Compared with the exemplar group, boron

/3 anf Smad7 protein, and RT-PCR was used to dejext TGF-ueta1 mRHA in reval tissues. Compared with thx moeel geoup, B

/3 and Smad7 protein, and RT-PCR was detect mRNA in tissues. Compared with

/3 and Smad7 protein, and RT-PCR was Used to deteCt TGF-BetA1 mRnA In reNal tIssues. Compared WIth tHe model group, B

/3 and Smad7 protein, andRT-PCR was  used  to  de te ct T GF-b eta1 mRNA in r e naltissues. Compared with  themo d el g r ou p, B

/3 and_Smad7 protein,_and RT-PCR was used_to detect_TGF-beta1_mRNA in_renal_tissues. Compared with_the model group,_B


additives in HDPE was studied in the 0.01-5% (m/m) range. For both Tinuvin P and Irganox 3

additives in HDPE was studied in the 0.01 - 5% (m / m) range. For both Tinuvin P and Irganox 3

adfitives in HDPE was studled in the 0.01-5% (m/m) rcbge. Foc both Finuvin O and Irganox 3

additives in HDPE was studied in the range. both Tinuvin and Irganox 3

additives in HDPE was studied In the 0.01-5% (m/m) ranGe. For BotH TiNuVin P And IRganox 3

additives in HDPE was stu died in th e 0.0 1-5 % ( m/ m) r ange . For both Tin u vinP and Irganox 3

additives_in HDPE_was studied in the_0.01-5% (m/m)_range._For both_Tinuvin_P and Irganox_3


oline I(1) receptor: AGN192403, rilmenidine, moxonidine and clonidine were used. The specific ligands of im

oline I(1) receptor: AGN192403, rilmenidine, moxonidine and clonidine were used. The specific ligands of i m

olije I(1) receptor: AGN192403, rilmenldine, moxonidine and clmnidins were ured. The specific ligands of mm

oline I(1) receptor: AGN192403, rilmenidine, moxonidine and used. specific ligands im

oline I(1) receptor: AGN192403, rilmenidIne, moxonidIne anD clOniDiNe weRe usEd. The specific lIGandS of im

oline I(1) receptor: AGN19 2403, rilm enidi ne,  mo xo nidi ne a nd clonidine w e re u sed. The specific liga nds o fi m

oline I(1)_receptor: AGN192403,_rilmenidine, moxonidine and clonidine_were used._The_specific ligands_of_im


sparse as compared with the standard case, where p=2. Unravel a neuroactive sHA sulfation pattern with neurogenesis activity by a library of defined

sparse as compared with the standard case, where p=2. Unravel a neuroactive sHA sulfation pattern with neurogenesis natural process by a library of define

spwrse as compared with tht standard case, wkwre p=2. Nnravel a neuroxctive sHA sulfation pattern wuth ntlrogenesis activity bh a libragy of defuned

sparse as compared with the standard case, Unravel neuroactive sHA pattern with neurogenesis defined

sparse as compared with the stAndard case, Where P=2. UnRavEl A neuRoacTive sHA sulfatiON patTern with neurogenesis acTivitY bY A libRArY of deFined

sparse as compared with t he standar d cas e,whe re  p=2 . Un ravel a neuroa c tive  sHA sulfation pattern  with  n e urog e ne sis a ctivity by a  li br ar y o fd ef ined

sparse_as compared_with the standard case,_where p=2._Unravel_a neuroactive_sHA_sulfation pattern with_neurogenesis activity by_a library of defined


permeability increased, relative to colostrum (all P < 0.05). In conclusion, enteral feeding is associated with gut dysfunction, microbial imbalance, and

permeability increased, relative to colostrum (all P < 0.05). In conclusion, enteric eating is associated with gut dysfunction, microbial asymmetry, and

pegmeability increased, relxtive to colosttun (all ' < 0.05). In donclusiun, enteral feeding is associeted with gut dysfunction, microcial imbapance, ane

permeability increased, relative to colostrum (all P In enteral feeding associated with gut

permeability increased, relaTive to coloStrum (All p < 0.05). In CoNcluSion, Enteral feeding IS assOciated with gut dysfunctIon, miCrOBial IMbAlancE, and

permeability increased, r elative to  colo str um(a ll P  < 0 .05). In concl u sion , enteral feeding is a ssoci at e d wi t hgut d ysfunct i on , mic ro bi alim b al ance,  an d

permeability_increased, relative_to colostrum (all P_< 0.05)._In_conclusion, enteral_feeding_is associated with_gut dysfunction, microbial_imbalance, and


uptake in neonatal rat cardiomyocytes via activation of the ET(A)-receptor. Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis

uptake in neonatal rat cardiomyocytes via activation of the ET(A)-receptor. Intramolecular cooperativity in a protein binding web site tax by combinatorial shotgun scanning mutagenesis

uphake in neonatal rat caraiomyocytes via activavion of the ET(A)-feceptor. Intramolecular coopxratuvity in a protein binding rite assedsed by xombmnatorial shotgui scanniky mutznenesns

uptake in neonatal rat cardiomyocytes via activation ET(A)-receptor. cooperativity in protein binding site mutagenesis

uptake in neonatal rat cardioMyocytes viA actiVatIon Of The Et(A)-reCeptor. IntramolECulaR cooperativity in a proteIn binDiNG sitE AsSesseD by combINaTORiaL sHoTguN sCAnNing mUtaGenesis

uptake in neonatal rat ca rdiomyocyt es vi a a cti va tion  ofthe ET(A)-rece p tor.  Intramolecular cooper ativi ty in a pr otein  bindin g  s i t e a ss es sed  b y  c ombin ato rial sh otgun scan nin gmutagenesis

uptake_in neonatal_rat cardiomyocytes via activation_of the_ET(A)-receptor._Intramolecular cooperativity_in_a protein binding_site assessed by_combinatorial shotgun scanning mutagenesis


Electron Microscopy investigations were performed on specimens from cultures treated for 6 hr with twice and tenfold the MSC. The present research confirms the good sterilizing

Electron Microscopy investigations were performed on specimens from cultures treat for 6 hour with twice and tenfold the MSC. The present research confirms the beneficial sterilizing

Elfctron Microscopy investlgations were petfirmed mn spedimens ffom cultures treated for 6 hr wuth tqice and tenfold the MRC. The prvsent reswarci confirms the good sterljizihn

Electron Microscopy investigations were performed on specimens treated 6 hr twice and tenfold confirms good sterilizing

Electron Microscopy investiGations werE perfOrmEd oN sPeciMens From cultures trEAted For 6 hr with twice and tenfoLd the mSc. the pREsEnt reSearch cONfIRMs tHe GoOd sTeRIlIzing

Electron Microscopy inves tigationswereper for me d on  spe cimens from cu l ture s treated for 6 hr wit h twi ce andt en foldthe MSC .  T h e  pr es en t r es e ar ch co nfi rms the  good ster ili zi ng

Electron_Microscopy investigations_were performed on specimens_from cultures_treated_for 6_hr_with twice and_tenfold the MSC._The present research confirms_the good sterilizing


the economic burden should be focused on hospitalisation. Due to skewed distribution, individual data must be considered in the analysis of the efforts. Identification of important abiotic

the economic burden should be focused on hospitalisation. Due to skewed distribution, individual datum must be view in the analysis of the feat. recognition of important abiotic

thf economic burden should be focused on kispitanisatikn. Due tu skewed distribution, indivivual data must be considered in the analjsis of tye ehforts. Identificefion of imporfwnt cbmotic

the economic burden should be focused on to distribution, individual must be considered efforts. of important abiotic

the economic burden should be Focused on hOspitAliSatIoN. Due To skEwed distributiON, indIvidual data must be consiDered In THe anALySis of The effoRTs. iDEntIfIcAtiOn OF iMportAnt Abiotic

the economic burden shoul d be focus ed on  ho spi ta lisa tion . Due to skewe d  dis tribution, individualdatamu s t be co nside red int he a nal ys is  of  t h eeffor ts.  Identi fication o f i mp ortant abiot i c

the_economic burden_should be focused on_hospitalisation. Due_to_skewed distribution,_individual_data must be_considered in the_analysis of the efforts._Identification of important_abiotic


theoretically decreasing the risk of recurrence in comparison with clip ligation. [Experimental study of miRNA200a regulating Wnt/β-catenin signaling pathway in silica-induced mouse

theoretically decreasing the risk of recurrence in comparison with clip ligation. [ Experimental study of miRNA200a determine Wnt / β - catenin sign pathway in silica - induced mouse

thforetically decreasing tme risk of recurtebce in compadison wigh clip ligation. [Experimentap wtudy of miRNA200a regulating Dnt/β-catenij signalung kathway in silica-mhduced mouse

theoretically decreasing the risk of recurrence in clip [Experimental study miRNA200a regulating Wnt/β-catenin

theoretically decreasing thE risk of recUrrenCe iN coMpArisOn wiTh clip ligation. [eXperImental study of miRNA200a reGulatInG wnt/β-CAtEnin sIgnalinG PaTHWay In SiLicA-iNDuCed moUse

theoretically decreasingthe risk o f rec urr enc ein c ompa rison with cli p  lig ation. [Experimental s tudyof miRN A 20 0a re gulatin g  W n t /β- ca te nin  s i gn aling  pa thway i n silica-i ndu ce d mouse

theoretically_decreasing the_risk of recurrence in_comparison with_clip_ligation. [Experimental_study_of miRNA200a regulating_Wnt/β-catenin signaling pathway_in silica-induced mouse


of bowel preparation before video capsule endoscopy (VCE) remains controversial. This study aimed to assess the ideal dose of PEG, based on small bowel visualization quality

of bowel preparation before video capsule endoscopy (VCE) remain controversial. This discipline aimed to assess the ideal dose of PEG, base on small bowel visual image quality

of bowel preparation befort video capsule eueoscopb (VCE) rsmains cuntroversial. This study aimev to assews the ideal dose of PDG, based ln small bowtl visualization quality

of bowel preparation before video capsule endoscopy controversial. study aimed assess the ideal small visualization quality

of bowel preparation before vIdeo capsulE endoScoPy (VcE) RemaIns cOntroversial. ThIS stuDy aimed to assess the ideaL dose Of peG, baSEd On smaLl bowel VIsUALizAtIoN quAlITy

of bowel preparation befo re video c apsul e e ndo sc opy(VCE ) remains cont r over sial. This study aimed  to a ss e ss t h eideal  dose o f  P E G , b as ed  on  s m al l bow elvisuali zation qua lit y

of_bowel preparation_before video capsule endoscopy_(VCE) remains_controversial._This study_aimed_to assess the_ideal dose of_PEG, based on small_bowel visualization quality


omas. The results suggest that low T3 and high T4/T3 ratio in nodular goitrous tissue could be due to grossly impaired thyroid

omas. The results suggest that low T3 and high T4 / T3 proportion in nodular goitrous tissue could be ascribable to grossly mar thyroid

omad. The results suggest thxt low T3 and hiyy T4/T3 retio in nodular goitrous tissue could be dux to groswly impaired thyroid

omas. The results suggest that low T3 T4/T3 in nodular tissue could be

omas. The results suggest that Low T3 and higH T4/T3 raTio In nOdUlar GoitRous tissue coulD Be duE to grossly impaired thyrOid

omas. The results suggestthat low T 3 and  hi ghT4 /T3rati o in nodular g o itro us tissue could be due  to g ro s slyi mp aired  thyroi d

omas. The_results suggest_that low T3 and_high T4/T3_ratio_in nodular_goitrous_tissue could be_due to grossly_impaired thyroid


C appeared to be in the phosphorylated inactive state. Incubation of intact phosphorylating A. suum muscle mitochondria in the absence of substrate and the presence of

C appeared to be in the phosphorylated inactive state. brooding of integral phosphorylating A. suum muscle mitochondria in the absence of substrate and the presence of

C aopeared to be in the phorphorylated inaerive svate. Indubation of intact phosphorylating A. syum myscle mitochondria in ghe absenbe of subwtraue and the presenrs of

C appeared to be in the phosphorylated Incubation intact phosphorylating suum muscle mitochondria and presence of

C appeared to be in the phosphoRylated inaCtive StaTe. INcUbatIon oF intact phosphoRYlatIng A. suum muscle mitochonDria iN tHE absENcE of suBstrate ANd THE prEsEnCe oF

C appeared to be in the ph osphorylat ed in act ive  s tate . In cubation of in t actphosphorylating A. suu m mus cl e  mit o ch ondri a in th e  a b s enc eof  su bs t ra te an d t he pres ence of

C appeared_to be_in the phosphorylated inactive_state. Incubation_of_intact phosphorylating_A._suum muscle mitochondria_in the absence_of substrate and the_presence of


and is a largely unappreciated cause of sudden death in the young. Clinical features of 12 domestic cats with ARVC (7 male; 1 to 20

and is a largely unappreciated cause of sudden death in the young. Clinical feature of 12 domestic cat with ARVC (7 male; 1 to 20

anf is a largely unapprecixted cause of sodeen deeth in fhe youne. Clinical features of 12 domedtuc cauf with ARVC (7 male; 1 to 20

and is a largely unappreciated cause of in young. Clinical of 12 domestic 1 20

and is a largely unappreciateD cause of suDden dEatH in ThE youNg. ClInical features OF 12 domEstic cats with ARVC (7 male; 1 tO 20

and is a largely unapprec iated caus e ofsud den  d eath  inthe young. Cli n ical  features of 12 domest ic ca ts with AR VC (7  male;1  t o 20

and_is a_largely unappreciated cause of_sudden death_in_the young._Clinical_features of 12_domestic cats with_ARVC (7 male; 1_to 20


% had no concurrent visceral injury. There were associated vascular injuries in 58% of patients, the inferior vena cava being the most frequent (37%). The

% had no concurrent visceral injury. There be consociate vascular injuries in 58% of patients, the inferior vein cava being the most frequent (37 %). The

% haf no concurrent visceral injury. There wgrw assoriated bascular injuries in 58% of patients, thx inderioe vena cava being the oost freqlent (37%). The

% had no concurrent visceral injury. There vascular in 58% patients, the inferior frequent The

% had no concurrent visceral inJury. There wEre asSocIatEd VascUlar Injuries in 58% of paTIentS, the inferior vena cava beIng thE mOSt frEQuEnt (37%). ThE

% had no concurrent viscer al injury.  Ther e w ere  a ssoc iate d vascular inj u ries  in 58% of patients, t he in fe r iorv en a cav a being th e mos tfr equ en t  ( 37%).  Th e

% had_no concurrent_visceral injury. There were_associated vascular_injuries_in 58%_of_patients, the inferior_vena cava being_the most frequent (37%)._The


olar vasomotor adjustments may forestall LEA in the larger collecting venules of the network, where venous obstruction may be countered by bringing the full weight

olar vasomotor adjustments may forestall LEA in the larger collecting venule of the net, where venous obstacle may be countered by bringing the full weight unit

olag vasomotor adjustments oay forestall LGA in thx larged collecging venules of the network, xherw venius obstruction may be counteref by bribginj the full weighv

olar vasomotor adjustments may forestall LEA in collecting of the where venous obstruction the weight

olar vasomotor adjustments mAy forestalL LEA iN thE laRgEr coLlecTing venules of tHE netWork, where venous obstrucTion mAy BE couNTeRed by BringinG ThE FUll WeIgHt

olar vasomotor adjustments  may fores tallLEA  in  t he l arge r collecting v e nule s of the network, wher e ven ou s  obs t ru ction  may be co u n ter ed  b y b ri n gi ng th e f ull wei ght

olar vasomotor_adjustments may_forestall LEA in the_larger collecting_venules_of the_network,_where venous obstruction_may be countered_by bringing the full_weight


of HBx sequesters Crm1 in the cytoplasm. Furthermore, HBx activates NFkappaB by inducing its nuclear translocation in a NES-dependent manner

of HBx sequesters Crm1 in the cytoplasm. Furthermore, HBx activates NFkappaB by inducing its nuclear translocation in a NES - dependent manner

of HBx sequesters Crm1 in tme cytoplasm. Furjhwrmore, HBx adtivates NFkappaB by inducing its nurleae trabslocation in a NES-depdndent majner

of HBx sequesters Crm1 in the cytoplasm. activates by inducing nuclear translocation in

of HBx sequesters Crm1 in the cyToplasm. FurThermOre, hBx AcTivaTes NfkappaB by inducINg itS nuclear translocation iN a NES-DePEndeNT mAnner

of HBx sequesters Crm1 in  the cytop lasm.  Fu rth er more , HB x activates NF k appa B by inducing its nucl ear t ra n sloc a ti on in  a NES- d ep e n den tma nne r

of_HBx sequesters_Crm1 in the cytoplasm._Furthermore, HBx_activates_NFkappaB by_inducing_its nuclear translocation_in a NES-dependent_manner


the addition of nutrients in the presence of fish resulted in a high algal biomass and daytime net autotrophy, reducing the CO(2) emissions by 35

the addition of nutrients in the presence of fish result in a eminent algal biomass and daytime net autotrophy, reducing the CO(2) emissions by 35

thf addition of nutrients ln the presence of fish resulfed in a high algal biomass and daytmme bet aytotrophy, reducing the CO(2) emisspons by 35

the addition of nutrients in the presence resulted a high biomass and daytime emissions 35

the addition of nutrients in tHe presence Of fisH reSulTeD in a High Algal biomass anD DaytIme net autotrophy, reduciNg the cO(2) EMissIOnS by 35

the addition of nutrients  in the pr esenc e o f f is h re sult ed in a high a l galbiomass and daytime ne t aut ot r ophy ,  r educi ng theC O( 2 )  em is si ons  b y  3 5

the_addition of_nutrients in the presence_of fish_resulted_in a_high_algal biomass and_daytime net autotrophy,_reducing the CO(2) emissions_by 35


and grading or staging of liver histology. Nonresponders to IFN had significantly high NIC HCV RNA titers compared with sustained responders (10(4.93 +/-

and grading or staging of liver histology. Nonresponders to IFN had significantly eminent NIC HCV RNA titer compared with sustained respondent (10(4.93 + /-

anf grading or staging of uiver histology. Nonres'onders to IFN fad significantly high NIC HRV RBA tiuvrs compared with susgained redponders (10(4.93 +/-

and grading or staging of liver histology. IFN significantly high HCV RNA titers +/-

and grading or staging of liveR histology. nonreSpoNdeRs To IFn had Significantly hIGh NIc HCV RNA titers compared wIth suStAIned REsPondeRs (10(4.93 +/-

and grading or staging of  liver his tolog y.Non re spon ders  to IFN had si g nifi cantly high NIC HCV RN A tit er s  com p ar ed wi th sust a in e d  re sp on der s( 10 (4.93  +/ -

and_grading or_staging of liver histology._Nonresponders to_IFN_had significantly_high_NIC HCV RNA_titers compared with_sustained responders (10(4.93 +/-


n = 887) was used as a group of reference. Both studies were undertaken in Pachuca City, the capital of Hidalgo, located 100

n = 887) was used as a group of reference. Both studies were undertaken in Pachuca City, the das kapital of Hidalgo, locate 100

n = 887) was used as a group of veference. Both sjueies wxre undsrtaken kn Pachuca City, the capital lf Hidaogo, located 100

n = 887) was used as a reference. studies were in Pachuca City, 100

n = 887) was used as a group of referenCe. Both studIes weRe uNdeRtAken In PaChuca City, the caPItal Of Hidalgo, located 100

n = 887) was used as a gro up of refe rence . B oth  s tudi es w ere undertaken in P achuca City, the capit al of  H i dalg o ,locat ed 100

n =_887) was_used as a group_of reference._Both_studies were_undertaken_in Pachuca City,_the capital of_Hidalgo, located 100


) at 7 days after surgery. Statistically significant factors affecting UTI prevalence included neurologic and urinary status, sex, administration of perioperative antibiotics, and amount

) at 7 days after surgery. Statistically significant factors involve UTI preponderance included neurologic and urinary condition, sex, government of perioperative antibiotics, and amount

) at 7 days after surgery. Stauistically signifnxant fectors zffectine UTI prevalence included nenroligic qnd urinary status, sex, administgation of permoperative antibmktics, akb amohkt

) at 7 days after surgery. Statistically affecting prevalence included and urinary status, and

) at 7 days after surgery. StatistIcally signIficaNt fActOrS affEctiNg UTI prevalencE InclUded neurologic and urinaRy staTuS, Sex, aDMiNistrAtion of PErIOPerAtIvE anTiBIoTics, aNd aMount

) at 7 days after surgery.  Statistic allysig nif ic antfact ors affectingU TI p revalence included neu rolog ic andu ri narystatus, se x ,  ad mi ni str at i on  of p eri operati ve antibio tic s,  and amount

) at_7 days_after surgery. Statistically significant_factors affecting_UTI_prevalence included_neurologic_and urinary status,_sex, administration of_perioperative antibiotics, and amount


akable' causal relationships between unrelated events and a paradoxical immunity to perceptual illusions, which are all known to be associated with schizophrenia. Detection and characterization of

akable' causal relationships between unrelated events and a paradoxical immunity to perceptual illusions, which are all know to be consociate with schizophrenia. Detection and characterization of

akahle' causal relationships between unrelajee evenvs and z paradobical immunity to perceptual iolusiins, which are all knowv to be adsociatee wiuh schizophrenia. Vstectiok and gharaetxrization of

akable' causal relationships between unrelated events and immunity perceptual illusions, are all known Detection characterization of

akable' causal relationships Between unrElateD evEntS aNd a pAradOxical immunity TO perCeptual illusions, which aRe all KnOWn to BE aSsociAted witH ScHIZopHrEnIa. DEtECtIon anD chAracterIzation of

akable' causal relationshi ps between  unre lat edev ents  and  a paradoxical immu nity to perceptual ill usion s, whic h  a re al l known to b e a ss oc iat ed wi th sc hiz ophreni a. Detecti onan d characteri z at ion of

akable' causal_relationships between_unrelated events and a_paradoxical immunity_to_perceptual illusions,_which_are all known_to be associated_with schizophrenia. Detection and_characterization of


and postoperatively, intravenous hyperalimentation, prophylactic antibiotics and low-dose heparin are undoubtedly important adjuncts to the improvements in surgical technique and judgment. Psychosexual

and postoperatively, intravenous hyperalimentation, prophylactic antibiotics and low - venereal disease heparin are undoubtedly authoritative adjuncts to the improvements in surgical technique and sagacity. Psychosexual

anf postoperatively, intravtnous hyperalimenjarion, pcophyladtic antkbiotics and low-dose heparin aee uneoubtedly important adguncts to the impeovenwnts in sucfical tcehniqhc and oudgment. Psychoxexual

and postoperatively, intravenous hyperalimentation, prophylactic antibiotics and are important adjuncts the improvements in

and postoperatively, intraveNous hyperaLimenTatIon, PrOphyLactIc antibiotics aND low-Dose heparin are undoubteDly imPoRTant ADjUncts To the imPRoVEMenTs In SurGiCAl TechnIquE and judGment. PsychOseXuAl

and postoperatively, intr avenous hy peral ime nta ti on,prop hylactic antib i otic s and low-dose heparin  areun d oubt e dl y imp ortanta dj u n cts  t othe  i m pr oveme nts  in sur gical tech niq ue  and judgmen t .Psychosexu al

and_postoperatively, intravenous_hyperalimentation, prophylactic antibiotics and_low-dose heparin_are_undoubtedly important_adjuncts_to the improvements_in surgical technique_and judgment. Psychosexual


OT), the Vanderbilt Pain Management Inventory (VPMI), the McGill Pain Questionnaire (MPQ), Hospital Anxiety and Depression Scale (HADS), and

OT), hhe Vanderbilt Pain Mananement Inventory (VPMI), tie McGiml Pain Duestionnaire (MPQ), Hospital Aixiery ane Depression Scale (HADR), and

OT), the Vanderbilt Pain Management Inventory (VPMI), Pain (MPQ), Hospital and Depression Scale

OT), the Vanderbilt Pain ManageMent InventOry (VPmI), tHe MCGIll PAin QUestionnaire (MPq), hospItal Anxiety and DepressiOn ScaLe (haDS), aND

OT), the Vanderbilt Pain M anagementInven tor y ( VP MI),  the  McGill Pain Q u esti onnaire (MPQ), Hospita l Anx ie t y an d  D epres sion Sc a le ( HAD S) ,and

OT), the_Vanderbilt Pain_Management Inventory (VPMI), the_McGill Pain_Questionnaire_(MPQ), Hospital_Anxiety_and Depression Scale_(HADS), and


to a CTD; the secondary outcome was the evaluation of predictors. Of 856 articles captured, 7 selected studies met the inclusion criteria. A total of 405

to a CTD; the secondary outcome was the evaluation of predictors. Of 856 articles get, 7 choose studies met the inclusion body criteria. A sum of 405

to a CTD; the secondary outgome was the evaluation of prsdictors. Of 856 articles captured, 7 selerted studues met the inclusion zriteria. W total if 405

to a CTD; the secondary outcome was of Of 856 captured, 7 selected A of 405

to a CTD; the secondary outcome Was the evalUatioN of PreDiCtorS. Of 856 aRticles captureD, 7 SeleCted studies met the incluSion cRiTEria. a ToTal of 405

to a CTD; the secondary o utcome was  theeva lua ti on o f pr edictors. Of 8 5 6 ar ticles captured, 7 sel ected  s t udie s  m et th e inclu s io n cri te ri a.At ot al of  40 5

to_a CTD;_the secondary outcome was_the evaluation_of_predictors. Of_856_articles captured, 7_selected studies met_the inclusion criteria. A_total of 405


analyzed their spatial expression patterns during development. Three out of four SULTs show distinct expression activity during embryogenesis, while the 4th SULT shows expression only

analyzed their spatial expression patterns during development. Three out of four SULTs picture discrete expression activity during embryogenesis, while the 4th SULT prove expression only

anwlyzed their spatial expvession patterns during develkpment. Tfree out of four SULTs show vistunct tqpression activity dufing embrjogenesis, whiow the 4th SNMT shows exprsdsiou inly

analyzed their spatial expression patterns during development. of SULTs show expression activity during shows only

analyzed their spatial expreSsion patteRns duRinG deVeLopmEnt. THree out of four SulTs sHow distinct expression aCtiviTy DUrinG EmBryogEnesis, wHIlE THe 4tH SuLt shOwS ExPressIon Only

analyzed their spatial ex pression p atter nsdur in g de velo pment. Three o u t of  four SULTs show disti nct e xp r essi o nactiv ity dur i ng e mbr yo ge nes is ,  w hilethe  4th SU LT shows e xpr es sion only

analyzed_their spatial_expression patterns during development._Three out_of_four SULTs_show_distinct expression activity_during embryogenesis, while_the 4th SULT shows_expression only


normal rabbit serum. Groups of animals were sacrificed for immunocytochemistry in 2 h intervals between 1300 and 2100 h. Double-label immunocytochemistry for FR

normal rabbit serum. Groups of animals were sacrificed for immunocytochemistry in 2 planck's constant interval between 1300 and 2100 h. Double - label immunocytochemistry for FR

nogmal rabbit serum. Groups of animals werg wacrifmced fod immunozytochemistry in 2 h intervald vetwetu 1300 and 2100 h. Double-labeu immunocjtochemisrry hor FR

normal rabbit serum. Groups of animals were immunocytochemistry 2 h between 1300 and FR

normal rabbit serum. Groups of Animals werE sacrIfiCed FoR immUnocYtochemistry in 2 H InteRvals between 1300 and 2100 h. Double-Label ImMUnocYToChemiStry for fr

normal rabbit serum. Grou ps of anim als w ere  sa cr ific ed f or immunocytoc h emis try in 2 h intervals b etwee n1 300a nd  2100  h. Dou b le - l abe lim mun oc y to chemi str y for F R

normal_rabbit serum._Groups of animals were_sacrificed for_immunocytochemistry_in 2_h_intervals between 1300_and 2100 h._Double-label immunocytochemistry for FR


summer of 2002 (n = 1283). Health Professional Stress Inventory modified for use in the nursing home setting and ratings of job satisfaction. The situations most stressful for

summer of 2002 (n = 1283). Health Professional Stress Inventory modified for use in the nursing home setting and rating of caper satisfaction. The situations most nerve-racking for

sulmer of 2002 (n = 1283). Health Proftssional Stress Iucentorb modifjed for jse in the nursing home settmng qnd rqtings of job satisfacgion. The dituatiobs miwt stressfnm for

summer of 2002 (n = 1283). Health Inventory for use the nursing home satisfaction. situations most stressful

summer of 2002 (n = 1283). Health ProfessionAl Stress InVentoRy mOdiFiEd foR use In the nursing hoME setTing and ratings of job satIsfacTiON. The SItUatioNs most sTReSSFul FoR

summer of 2002 (n = 1283) . Health P rofes sio nal  S tres s In ventory modifi e d fo r use in the nursing h ome s et t inga nd  rati ngs ofj ob s ati sf ac tio n. Th e sit uat ions mo st stressf ulfo r

summer_of 2002_(n = 1283). Health_Professional Stress_Inventory_modified for_use_in the nursing_home setting and_ratings of job satisfaction._The situations most_stressful_for


, to our knowledge, grape poisoning has not been identified by pathologic and clinicopathologic basis until this writing in Korea. Education and knowledge about the risks of grape

, to our knowledge, grape poisoning has not been identified by pathologic and clinicopathologic footing until this writing in Korea. department of education and cognition about the risks of grape

, to our knowledge, grape poironing has not ywen idxntifies by patfologic and clinicopathologir bawis ubtil this writing in Kurea. Educwtion ane kniqledge abonf the rlfks kn gra'e

, to our knowledge, grape poisoning has identified pathologic and basis until this knowledge the risks of

, to our knowledge, grape poisonIng has not bEen idEntIfiEd By paTholOgic and clinicoPAthoLogic basis until this wriTing iN KORea. EDUcAtion And knowLEdGE AboUt ThE riSkS Of Grape

, to our knowledge, grapepoisoninghas n otbee niden tifi ed by patholog i c an d clinicopathologic ba sis u nt i l th i swriti ng in K o re a .  Ed uc at ion  a n dknowl edg e about  the risks  of  g rape

, to_our knowledge,_grape poisoning has not_been identified_by_pathologic and_clinicopathologic_basis until this_writing in Korea._Education and knowledge about_the risks of_grape


spiroperidol in calf caudate.
The effect of typical and atypical neuroleptics on the binding of [3H]spiroper

spiroperidol in calf caudate.
 The effect of typical and atypical neuroleptics on the dressing of [ 3H]spiroper

spigoperidol in calf caudatt.
The effect of tykixal anv atypidal neuruleptics on the binding of [3H]dpuropee

spiroperidol in calf caudate. The effect of atypical on the of [3H]spiroper

spiroperidol in calf caudate.
the effect oF typiCal And AtYpicAl neUroleptics on thE BindIng of [3H]spiroper

spiroperidol in calf cauda te.
The ef fectoftyp ic al a nd a typical neurol e ptic s on the binding of [3 H]spi ro p er

spiroperidol in_calf caudate.
The_effect of typical and_atypical neuroleptics_on_the binding_of_[3H]spiroper


 D1 reflected the prolefiration of pancreas cancer cells. Nucleation of microbiologic calcification by proteolipid.
The component of crude phospholipid

 D1 geflected the prolefiratlon of pancreas eqncer rells. Nhcleatiov of microbiologic calcificavion by peoteolipid.
The componeng of crudv phosphooipiv

D1 reflected the prolefiration of pancreas cancer of calcification by The component of

 D1 reflected the prolefiratioN of pancreaS cancEr cEllS. NUcleAtioN of microbiologIC calCification by proteolipiD.
The cOmPOnenT Of Crude PhosphoLIpID

 D1 reflected the prolefir ation of p ancre ascan ce r ce lls.  Nucleation of micr obiologic calcificatio n bypr o teol i pi d.
Th e compo n en t ofcr ud e p ho s ph olipi d

 D1_reflected the_prolefiration of pancreas cancer_cells. Nucleation_of_microbiologic calcification_by_proteolipid.
The component of_crude phospholipid


 England.
The present qualitative study explored health perceptions, diet and the social construction of obesity and how this relates to the initiation and maintenance of a healthier diet in

England.
 The present qualitative study explored health perceptions, diet and the social construction of fleshiness and how this relate to the initiation and maintenance of a healthy diet in

 Enhland.
The present qualitauive study explorgd healti perceltions, dket and the social constructmon if obtfity and how this felates tl the inutiauion and maintenaide of a healtgler dnev in

England. The present qualitative study explored health and social construction obesity and how and of a healthier in

 England.
The present qualitatIve study exPloreD heAltH pErcePtioNs, diet and the soCIal cOnstruction of obesity anD how tHiS RelaTEs To the InitiatIOn AND maInTeNanCe OF a HealtHieR diet in

 England.
The present qual itative st udy e xpl ore dheal th p erceptions, di e t an d the social construct ion o fo besi t yand h ow this re l a tes  t othe  i n it iatio n a nd main tenance of  ahe althier diet in

 England.
The_present qualitative_study explored health perceptions,_diet and_the_social construction_of_obesity and how_this relates to_the initiation and maintenance_of a healthier_diet_in


2-CDG have been described so far. A 4-year-old girl who initially presented with symptoms resulting from raised intracranial pressure underwent acute neurosurgical intervention

2 - CDG have been described so far. A 4 - year - old girlfriend who initially confront with symptoms resulting from raised intracranial imperativeness underwent acute neurosurgical intervention

2-CDG have been described so nar. A 4-year-old gitl who iiitiallg presenged with symptoms resulting hrom raistb intracranial pressjre underaent acure nturosurgical intecbention

2-CDG have been described so far. A who presented with resulting from raised intervention

2-CDG have been described so far. a 4-year-old giRl who IniTiaLlY preSentEd with symptoms REsulTing from raised intracraNial pReSSure UNdErwenT acute nEUrOSUrgIcAl IntErVEnTion

2-CDG have been describedso far. A4-yea r-o ldgi rl w ho i nitially prese n tedwith symptoms resultin g fro mr aise d  i ntrac ranialp re s s ure  u nd erw en t  a cuteneu rosurgi cal interv ent io n

2-CDG have_been described_so far. A 4-year-old_girl who_initially_presented with_symptoms_resulting from raised_intracranial pressure underwent_acute neurosurgical intervention


the United States, especially among African-Americans. Additional studies are needed to assess the impact of the DASH diet on CHD risk in free-living subjects

the United States, especially among African - Americans. Additional studies are needed to measure the impingement of the DASH diet on CHD risk in free - animation subjects

thf United States, especialuy among Africau-Qmericens. Addjtional rtudies are needed to assess tye imkcct of the DASH diet on CHD rpsk in frwe-liting subjects

the United States, especially among African-Americans. Additional needed assess the of the DASH free-living

the United States, especially Among AfricAn-AmeRicAns. adDitiOnal Studies are needED to aSsess the impact of the DASh diet On chD riSK iN free-Living sUBjECTs

the United States, especi ally among  Afri can -Am er ican s. A dditional stud i es a re needed to assess th e imp ac t  oft he  DASH  diet o n  C H D  ri sk  i n f re e -l iving  su bjects

the_United States,_especially among African-Americans. Additional_studies are_needed_to assess_the_impact of the_DASH diet on_CHD risk in free-living_subjects


+ cells were predominantly mature CD4+CD8- cells as measured by three-color flow cytometry. After culture with PHA-P and IL-2

+ cells were predominantly mature CD4+CD8- cells as measured by three - semblance menstruation cytometry. After culture with PHA - P and IL-2

+ cepls were predominantly mxture CD4+CD8- cells as meesured gy three-zolor flow cytometry. After cnltuee wiuk PHA-P and IL-2

+ cells were predominantly mature CD4+CD8- cells by flow cytometry. culture with PHA-P

+ cells were predominantly matUre CD4+CD8- celLs as mEasUreD bY thrEe-coLor flow cytometRY. AftEr culture with PHA-P and IL-2

+ cells were predominantly  mature CD 4+CD8 - c ell sas m easu red by three-c o lorflow cytometry. Aftercultu re with PH A-P a nd IL-2

+ cells_were predominantly_mature CD4+CD8- cells as_measured by_three-color_flow cytometry._After_culture with PHA-P_and IL-2


all-cause and CV-related. However, hospitalization for HF are reduced by ≈ 33% and occur regardless of baseline patient characteristics. The unprecedented HF outcomes

all - cause and CV - related. However, hospitalization for HF are dilute by ≈ 33% and happen regardless of baseline patient characteristics. The unprecedented HF outcomes

all-fause and CV-related. Howeyer, hospitalizatnin for HF ars reducea by ≈ 33% and occur regardless lf baseoine patient characterkstics. Thv unpreceeenttd HF outcomes

all-cause and CV-related. However, hospitalization for HF by 33% and regardless of baseline outcomes

all-cause and CV-related. HowevEr, hospitalIzatiOn fOr Hf aRe reDuceD by ≈ 33% and occur regARdleSs of baseline patient chaRacteRiSTics. tHe UnpreCedenteD hF OUTcoMeS

all-cause and CV-related.However, h ospit ali zat io n fo r HF  are reduced b y  ≈ 3 3% and occur regardles s ofba s elin e  p atien t chara c te r i sti cs .The  u n pr ecede nte d HF ou tcomes

all-cause and_CV-related. However,_hospitalization for HF are_reduced by_≈_33% and_occur_regardless of baseline_patient characteristics. The_unprecedented HF outcomes