There are 60 minutes in an hour, so the superhero will run 60 / 4 = <<60/4=15>>15 intervals of 10 miles in an hour.
Thus, the superhero can run 15 * 10 = <<15*10=150>>150 miles in an hour.
The superhero can run 150 - 100 = <<150-100=50>>50 miles farther than the supervillain can drive in an hour.
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