One cheesecake was 30% cheaper than the apple pie, which means, it was 25/100 * 12 = $3 cheaper.
So for one cheesecake, Natalie needed to pay 12 - 3 = $<<12-3=9>>9.
The six-pack of muffins was two times more expensive than the cheesecake, which means its price was 9 * 2 = $<<9*2=18>>18.
So for two cheesecakes, Natalie paid also 9 * 2 = $<<9*2=18>>18.
So for all her shopping she paid 18 + 18 + 12 = $<<18+18+12=48>>48.
#### 48