What are the signs and symptoms of Behcet's disease? Symptoms of Behcet's disease include recurrent ulcers in the mouth (resembling canker sores) and on the genitals, and eye inflammation (uveitis). The disorder may also cause various types of skin lesions, arthritis, bowel inflammation, meningitis (inflammation of the membranes of the brain and spinal cord), and cranial nerve palsies. Behcet's is a multi-system disease; it may involve all organs and affect the central nervous system, causing memory loss and impaired speech, balance, and movement. The effects of the disease may include blindness, stroke, swelling of the spinal cord, and intestinal complications. The Human Phenotype Ontology provides the following list of signs and symptoms for Behcet's disease. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Abnormality of temperature regulation 90% Arthritis 90% Meningitis 90% Migraine 90% Myalgia 90% Nausea and vomiting 90% Orchitis 90% Photophobia 90% Vasculitis 90% Abdominal pain 50% Abnormal blistering of the skin 50% Acne 50% Arthralgia 50% Gait disturbance 50% Gastrointestinal hemorrhage 50% Hemiplegia/hemiparesis 50% Immunologic hypersensitivity 50% Reduced consciousness/confusion 50% Thrombophlebitis 50% Abnormal pyramidal signs 7.5% Abnormality of the aortic valve 7.5% Abnormality of the endocardium 7.5% Abnormality of the mitral valve 7.5% Abnormality of the myocardium 7.5% Abnormality of the pericardium 7.5% Abnormality of the pleura 7.5% Anorexia 7.5% Arterial thrombosis 7.5% Aseptic necrosis 7.5% Cataract 7.5% Cerebral ischemia 7.5% Coronary artery disease 7.5% Cranial nerve paralysis 7.5% Developmental regression 7.5% Encephalitis 7.5% Gangrene 7.5% Glomerulopathy 7.5% Hemoptysis 7.5% Hyperreflexia 7.5% Incoordination 7.5% Increased intracranial pressure 7.5% Keratoconjunctivitis sicca 7.5% Lymphadenopathy 7.5% Malabsorption 7.5% Memory impairment 7.5% Myositis 7.5% Pancreatitis 7.5% Paresthesia 7.5% Polyneuropathy 7.5% Pulmonary embolism 7.5% Pulmonary infiltrates 7.5% Renal insufficiency 7.5% Retinopathy 7.5% Retrobulbar optic neuritis 7.5% Seizures 7.5% Splenomegaly 7.5% Vertigo 7.5% Visual impairment 7.5% Weight loss 7.5% Alopecia areata - Chorioretinitis - Epididymitis - Erythema - Genital ulcers - Iridocyclitis - Iritis - Irritability - Oral ulcer - Superficial thrombophlebitis - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.