Key Points
                    - Adult Hodgkin lymphoma is a disease in which malignant (cancer) cells form in the lymph system.    - There are two main types of Hodgkin lymphoma: classical and nodular lymphocyte-predominant.    - Age, gender, and Epstein-Barr infection can affect the risk of adult Hodgkin lymphoma.     - Signs of adult Hodgkin lymphoma include swollen lymph nodes, fever, night sweats, and weight loss.     - Tests that examine the lymph nodes are used to detect (find) and diagnose adult Hodgkin lymphoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Adult Hodgkin lymphoma is a disease in which malignant (cancer) cells form in the lymph system.
                    Adult Hodgkin lymphoma is a type of cancer that develops in the lymph system, part of the body's immune system. The immune system protects the body from foreign substances, infection, and diseases. The lymph system is made up of the following:         -  Lymph: Colorless, watery fluid that carries white blood cells called lymphocytes through the lymph system. Lymphocytes protect the body against infections and the growth of tumors.    -  Lymph vessels: A network of thin tubes that collect lymph from different parts of the body and return it to the bloodstream.     -  Lymph nodes: Small, bean-shaped structures that filter lymph and store white blood cells that help fight infection and disease. Lymph nodes are located along the network of lymph vessels found throughout the body. Clusters of lymph nodes are found in the neck, underarm, abdomen, pelvis, and groin.    -  Spleen: An organ that makes lymphocytes, filters the blood, stores blood cells, and destroys old blood cells. It is located on the left side of the abdomen near the stomach.    -  Thymus: An organ in which lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.    -  Tonsils: Two small masses of lymph tissue at the back of the throat. The tonsils make lymphocytes.    -  Bone marrow: The soft, spongy tissue in the center of large bones. Bone marrow makes white blood cells, red blood cells, and platelets.         Lymph tissue is also found in other parts of the body such as the stomach, thyroid gland, brain, and skin. Cancer can spread to the liver and lungs.    Lymphomas are divided into two general types: Hodgkin lymphoma and non-Hodgkin lymphoma. This summary is about the treatment of adult Hodgkin lymphoma. (See the PDQ summary on Adult Non-Hodgkin Lymphoma Treatment for more information.)   Hodgkin lymphoma can occur in both adults and children. Treatment for adults is different than treatment for children. Hodgkin lymphoma may also occur in patients who have acquired immunodeficiency syndrome (AIDS); these patients require special treatment.    See the following PDQ summaries for more information:         -  Childhood Hodgkin Lymphoma Treatment     -  AIDS-Related Lymphoma Treatment         Hodgkin lymphoma in pregnant women is the same as the disease in nonpregnant women of childbearing age. However, treatment is different for pregnant women. This summary includes information about treating Hodgkin lymphoma during pregnancy.
                
                
                    There are two main types of Hodgkin lymphoma: classical and nodular lymphocyte-predominant.
                    Most Hodgkin lymphomas are the classical type. The classical type is broken down into the following four subtypes:         - Nodular sclerosing Hodgkin lymphoma.    - Mixed cellularity Hodgkin lymphoma.    - Lymphocyte depletion Hodgkin lymphoma.    - Lymphocyte-rich classical Hodgkin lymphoma.