bowang0911/MedQuAD huggingface dataset:
Key Points
                    - Liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.    - Liver cancer is not common in the United States.    - Being infected with certain types of the hepatitis virus can cause hepatitis and increase the risk of liver cancer.         - Hepatitis A     - Hepatitis B     - Hepatitis C     - Hepatitis D     - Hepatitis E     - Hepatitis G
                
                
                    Liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.
                    The liver is one of the largest organs in the body. It has four lobes and fills the upper right side of the abdomen inside the rib cage. Three of the many important functions of the liver are:         - To filter harmful substances from the blood so they can be passed from the body in stools and urine.    - To make bile to help digest fats from food.     - To store glycogen (sugar), which the body uses for energy.          See the following PDQ summaries for more information about liver (hepatocellular) cancer:         -  Liver (Hepatocellular) Cancer Screening     -  Adult Primary Liver Cancer Treatment     -  Childhood Liver Cancer Treatment
                
                
                    Liver cancer is not common in the United States.
                    Liver cancer is the fourth most common cancer and the third leading cause of cancer death in the world. In the United States, men, especially Asian/Pacific Islander men, have an increased risk of liver cancer. The number of new cases of liver cancer and the number of deaths from liver cancer continue to increase, especially among middle-aged black, Hispanic, and white men. People are usually older than 40 years when they develop this cancer.    Finding and treating liver cancer early may prevent death from liver cancer.
Cancer prevention clinical trials are used to study ways to prevent cancer.
                    Cancer prevention clinical trials are used to study ways to lower the risk of developing certain types of cancer. Some cancer prevention trials are conducted with healthy people who have not had cancer but who have an increased risk for cancer. Other prevention trials are conducted with people who have had cancer and are trying to prevent another cancer of the same type or to lower their chance of developing a new type of cancer. Other trials are done with healthy volunteers who are not known to have any risk factors for cancer.    The purpose of some cancer prevention clinical trials is to find out whether actions people take can prevent cancer. These may include eating fruits and vegetables, exercising, quitting smoking, or taking certain medicines, vitamins, minerals, or food supplements.
                
                
                    New ways to prevent liver cancer are being studied in clinical trials.
                    Clinical trials are taking place in many parts of the country. Information about clinical trials can be found in the Clinical Trials section of the NCI website. Check NCI's list of cancer clinical trials for liver cancer prevention trials that are now accepting patients.
Key Points
                    - A gastrointestinal carcinoid tumor is cancer that forms in the lining of the gastrointestinal tract.     -  Health history can affect the risk of gastrointestinal carcinoid tumors.     - Some gastrointestinal carcinoid tumors have no signs or symptoms in the early stages.     -  Carcinoid syndrome may occur if the tumor spreads to the liver or other parts of the body.     - Imaging studies and tests that examine the blood and urine are used to detect (find) and diagnose gastrointestinal carcinoid tumors.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    A gastrointestinal carcinoid tumor is cancer that forms in the lining of the gastrointestinal tract.
                    The gastrointestinal (GI) tract is part of the body's digestive system. It helps to digest food, takes nutrients (vitamins, minerals, carbohydrates, fats, proteins, and water) from food to be used by the body and helps pass waste material out of the body. The GI tract is made up of these and other organs:         -  Stomach.    -  Small intestine (duodenum, jejunum, and ileum).    -  Colon.    -  Rectum.          Gastrointestinal carcinoid tumors form from a certain type of neuroendocrine cell (a type of cell that is like a nerve cell and a hormone -making cell). These cells are scattered throughout the chest and abdomen but most are found in the GI tract. Neuroendocrine cells make hormones that help control digestive juices and the muscles used in moving food through the stomach and intestines. A GI carcinoid tumor may also make hormones and release them into the body.   GI carcinoid tumors are rare and most grow very slowly. Most of them occur in the small intestine, rectum, and appendix. Sometimes more than one tumor will form.    See the following PDQ summaries for more information related to GI and other types of carcinoid tumors:         -  Non-Small Cell Lung Cancer Treatment.    -  Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment.     -  Rectal Cancer Treatment.    -  Small Intestine Cancer Treatment.    -  Unusual Cancers of Childhood Treatment
                
                
                    Carcinoid syndrome may occur if the tumor spreads to the liver or other parts of the body.
                    The hormones made by gastrointestinal carcinoid tumors are usually destroyed by liver enzymes in the blood. If the tumor has spread to the liver and the liver enzymes cannot destroy the extra hormones made by the tumor, high amounts of these hormones may remain in the body and cause carcinoid syndrome. This can also happen if tumor cells enter the blood. Signs and symptoms of carcinoid syndrome include the following:         - Redness or a feeling of warmth in the face and neck.     - Abdominal pain.    - Feeling bloated.    - Diarrhea.    - Wheezing or other trouble breathing.    - Fast heartbeat.        These signs and symptoms may be caused by gastrointestinal carcinoid tumors or by other conditions. Talk to your doctor if you have any of these signs or symptoms.
Health history can affect the risk of gastrointestinal carcinoid tumors. Anything that increases a person's chance of developing a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk to your doctor if you think you may be at risk.    Risk factors for GI carcinoid tumors include the following:         - Having a family history of multiple endocrine neoplasia type 1 (MEN1) syndrome or neurofibromatosis type 1 (NF1) syndrome.     - Having certain conditions that affect the stomach's ability to make stomach acid, such as atrophic gastritis, pernicious anemia, or Zollinger-Ellison syndrome.
Some gastrointestinal carcinoid tumors have no signs or symptoms in the early stages.Signs and symptoms may be caused by the growth of the tumor and/or the hormones the tumor makes. Some tumors, especially tumors of the stomach or appendix, may not cause signs or symptoms. Carcinoid tumors are often found during tests or treatments for other conditions.    Carcinoid tumors in the small intestine (duodenum, jejunum, and ileum), colon, and rectum sometimes cause signs or symptoms as they grow or because of the hormones they make. Other conditions may cause the same signs or symptoms. Check with your doctor if you have any of the following:         -  Duodenum  Signs and symptoms of GI carcinoid tumors in the duodenum (first part of the small intestine, that connects to the stomach) may include the following:                  -  Abdominal pain.       -  Constipation.       -  Diarrhea.       - Change in stool color.       -  Nausea.       -  Vomiting.       -  Jaundice (yellowing of the skin and whites of the eyes).       - Heartburn.                -  Jejunum and ileum  Signs and symptoms of GI carcinoid tumors in the jejunum (middle part of the small intestine) and ileum (last part of the small intestine, that connects to the colon) may include the following:                  -  Abdominal pain.       - Weight loss for no known reason.       - Feeling very tired.       - Feeling bloated       -  Diarrhea.       -  Nausea.       - Vomiting.                -  Colon  Signs and symptoms of GI carcinoid tumors in the colon may include the following:                  - Abdominal pain.       - Weight loss for no known reason.                -  Rectum  Signs and symptoms of GI carcinoid tumors in the rectum may include the following:                  -  Blood in the stool.       - Pain in the rectum.       -  Constipation.
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Where the tumor is in the gastrointestinal tract.    - The size of the tumor.     - Whether the cancer has spread from the stomach and intestines to other parts of the body, such as the liver or lymph nodes.    - Whether the patient has carcinoid syndrome or has carcinoid heart syndrome.    - Whether the cancer can be completely removed by surgery.     - Whether the cancer is newly diagnosed or has recurred.
New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Targeted therapy      Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells without harming normal cells. Several types of targeted therapy are being studied in the treatment of GI carcinoid tumors.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Key Points
                    - Neuroblastoma is a disease in which malignant (cancer) cells form in neuroblasts (immature nerve tissue) in the adrenal gland, neck, chest, or spinal cord.    - Neuroblastoma is sometimes caused by a gene mutation (change) passed from the parent to the child.    - Signs and symptoms of neuroblastoma include bone pain and a lump in the abdomen, neck, or chest.     - Tests that examine many different body tissues and fluids are used to detect (find) and diagnose neuroblastoma.    - A biopsy is done to diagnose neuroblastoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Neuroblastoma is a disease in which malignant (cancer) cells form in neuroblasts (immature nerve tissue) in the adrenal gland, neck, chest, or spinal cord.
                    Neuroblastoma often begins in the nerve tissue of the adrenal glands. There are two adrenal glands, one on top of each kidney in the back of the upper abdomen. The adrenal glands make important hormones that help control heart rate, blood pressure, blood sugar, and the way the body reacts to stress. Neuroblastoma may also begin in nerve tissue in the neck, chest, abdomen or pelvis.      Neuroblastoma most often begins in infancy and may be diagnosed in the first month of life. It is found when the tumor begins to grow and cause signs or symptoms. Sometimes it forms before birth and is found during a fetal ultrasound.   By the time neuroblastoma is diagnosed, the cancer has usually metastasized (spread). Neuroblastoma spreads most often to the lymph nodes, bones, bone marrow, and liver. In infants, it also spreads to the skin.
Signs and symptoms of neuroblastoma include bone pain and a lump in the abdomen, neck, or chest.The most common signs and symptoms of neuroblastoma are caused by the tumor pressing on nearby tissues as it grows or by cancer spreading to the bone. These and other signs and symptoms may be caused by neuroblastoma or by other conditions.   Check with your childs doctor if your child has any of the following:         - Lump in the abdomen, neck, or chest.    - Bulging eyes.    - Dark circles around the eyes ("black eyes").    - Bone pain.    - Swollen stomach and trouble breathing (in infants).    - Painless, bluish lumps under the skin (in infants).    - Weakness or paralysis (loss of ability to move a body part).        Less common signs and symptoms of neuroblastoma include the following:         -  Fever.    - Shortness of breath.    - Feeling tired.    - Easy bruising or bleeding.    -  Petechiae (flat, pinpoint spots under the skin caused by bleeding).    -  High blood pressure.     - Severe watery diarrhea.    -  Horner syndrome (droopy eyelid, smaller pupil, and less sweating on one side of the face).    - Jerky muscle movements.    - Uncontrolled eye movements.
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Age of the child at the time of diagnosis.    - The child's risk group.    - Whether there are certain changes in the genes.    - Where in the body the tumor started.    - Tumor histology (the shape, function, and structure of the tumor cells).    - Whether there is cancer in the lymph nodes on the same side of the body as the primary cancer or whether there is cancer in the lymph nodes on the opposite side of the body.    - How the tumor responds to treatment.    - How much time passed between diagnosis and when the cancer recurred (for recurrent cancer).        Prognosis and treatment options for neuroblastoma are also affected by tumor biology, which includes:          - The patterns of the tumor cells.    - How different the tumor cells are from normal cells.    - How fast the tumor cells are growing.    - Whether the tumor shows MYCN amplification.    - Whether the tumor has changes in the ALK gene.         The tumor biology is said to be favorable or unfavorable, depending on these factors. A favorable tumor biology means there is a better chance of recovery.   In some children up to 6 months old, neuroblastoma may disappear without treatment. This is called spontaneous regression. The child is closely watched for signs or symptoms of neuroblastoma. If signs or symptoms occur, treatment may be needed.
New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Immunotherapy     Immunotherapy is a treatment that uses the patients immune system to fight cancer. Substances made by the body or made in a laboratory are used to boost, direct, or restore the bodys natural defenses against cancer. This type of cancer treatment is also called biotherapy or biological therapy.     Vaccine therapy uses a substance to stimulate the immune system to destroy a tumor. Vaccine therapy is being studied to treat neuroblastoma that has come back after treatment.       Other drug therapy     Lenalidomide is a type of angiogenesis inhibitor. It prevents the growth of new blood vessels that are needed by a tumor to grow.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Having certain inherited disorders can increase the risk of an extracranial germ cell tumor. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your childs doctor if you think your child may be at risk.    Possible risk factors for extracranial germ cell tumors include the following:         - Having certain genetic syndromes:               -  Klinefelter syndrome may increase the risk of germ cell tumors in the mediastinum.      - Swyer syndrome may increase the risk of germ cell tumors in the testicles or ovaries.      - Turner syndrome may increase the risk of germ cell tumors in the ovaries.             - Having an undescended testicle may increase the risk of developing a testicular germ cell tumor.
Signs of childhood extracranial germ cell tumors depend on the type of tumor and where it is in the body. Different tumors may cause the following signs and symptoms. Other conditions may cause these same signs and symptoms. Check with a doctor if your child has any of the following:         - A lump in the abdomen or lower back.    -  A painless lump in the testicle.    - Pain in the abdomen.    -  Fever.    -  Constipation.    - In females, no menstrual periods.    - In females, unusual vaginal bleeding.
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The type of germ cell tumor.    - Where the tumor first began to grow.    - The stage of the cancer (whether it has spread to nearby areas or to other places in the body).    - How well the tumor responds to treatment (lower AFP and -hCG levels).    - Whether the tumor can be completely removed by surgery.    - The patient's age and general health.    - Whether the cancer has just been diagnosed or has recurred (come back).        The prognosis for childhood extracranial germ cell tumors, especially ovarian germ cell tumors, is good.
New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     High-dose chemotherapy with stem cell transplant     High-dose chemotherapy with stem cell transplant is a way of giving high doses of chemotherapy and replacing blood -forming cells destroyed by the cancer treatment. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After the chemotherapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the body's blood cells.       Radiation therapy     Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. There are two types of radiation therapy:            -  External radiation therapy uses a machine outside the body to send radiation toward the cancer.     -  Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer.           The way the radiation therapy is given depends on the type of cancer and whether it has come back. External radiation therapy is being studied for the treatment of childhood extracranial germ cell tumors that have come back.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.