Normal Simple association between maternal vitamin d status in pregnancy and neurodevelopmental outcomes in childhood results from the avon longitudinal study of parents and children alspac insufficient levels of vitamin d in pregnancy detrimental to child development silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury possible treatment found for suppressed immunity from spine injuries plasmid encoded proinsulin preserves c peptide while specifically reducing proinsulin specific cd t cells in type diabetes dna reverse vaccine reduces levels of immune cells believed responsible for type diabetes spread of classic bse prions from the gut via the peripheral nervous system to the brain mad cow disease in cattle can spread widely in autonomic nervous system before detectable in the central nervous system children of depressed mothers year after remission of maternal depression findings from the star d child study successful depression treatment of mothers has long term effects on offspring health care workers mandatory influenza vaccination policies and the law implications of mandatory flu vaccinations for health care workers google flu trends correlation with emergency department influenza rates and crowding metrics google flu trends is a powerful early warning system for emergency departments association of pandemic influenza a h n infection and increased hospitalization with parapneumonic empyema in children in utah h n flu linked to serious bacterial infections in children increased oxygen tension attenuates acute ultraviolet b induced skin angiogenesis and wrinkle formation hyperoxia may slow formation of wrinkles excess oxygen lessens impact of uvb radiation study shows using million year old amber to test the super arrhenius behaviour of glass forming systems million year old amber shatters theories of glass as a liquid silencing of small valosin containing protein interacting protein svip reduces very low density lipoprotein vldl secretion from rat hepatocytes by disrupting its endoplasmic reticulum er to golgi trafficking damage to tiny liver protein function leads to heart disease fatty liver tinagl suppresses triple negative breast cancer progression and metastasis by simultaneously inhibiting integrin fak and egfr signaling experimental treatment shows promise against triple negative breast cancer weight loss as a predictor of cancer in primary care a systematic review and meta analysis weight loss is an important predictor of cancer highly parallel interferometric diffusing wave spectroscopy for monitoring cerebral blood flow dynamics new technology for measuring brain blood flow with light reconciling the dawn dusk asymmetry in mercury s exosphere with the micrometeoroid impact directionality small collisions make big impact on mercury s thin atmosphere metabolic phenotype and risk of colorectal cancer in normal weight postmenopausal women poor metabolic health in some normal weight women may increase risk for colorectal cancer temporal changes of site response during the mw. tohoku earthquake in japan study of soil effects from march japan earthquake could improve building design milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture the framingham offspring study new study sheds light on link between dairy intake and bone health not all dairy products are equal emergence of blueschists on earth linked to secular changes in oceanic crust composition age of blueschist is not an indicator of the date of emergence of plate tectonics a comparative study of cybersickness during exposure to virtual reality and classic motion sickness are they different ? motion sickness vs. cybersickness two different problems or the same condition ? multibody dynamics model of head and neck function in allosaurus dinosauria theropoda allosaurus fed more like a falcon than a crocodile engineering anatomy work reveals differences in dinosaur feeding styles sensory adapted dental environments to enhance oral care for children with autism spectrum disorders a randomized controlled pilot study for children with autism trips to the dentist just got easier adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high fat diet withdrawal could ending your fatty food habit cause withdrawal symptoms and depression ? public reaction to the death of steve jobs implications for cancer communication death of public figures provides important opportunities for health education epidemiology of blunt head trauma in children in u.s. emergency departments major study sends clear safety message to prevent brain injury in children factors associated with failure of emergency department management in children with acute moderate or severe asthma a prospective multicentre cohort study children with asthma attacks triggered by colds less responsive to standard treatment chronology of onset of mental disorders and physical diseases in mental physical comorbidity a national representative survey of adolescents depression in young people affects the stomach anxiety the skin maternal experiences of intimate partner violence and child morbidity in bangladesh evidence from a national bangladeshi sample violence against mothers in bangladesh associated with health problems in young children longitudinal trajectory of sexual functioning after hematopoietic cell transplantation impact of chronic graft vs. host disease and total body irradiation study ties bone marrow transplant to negative sexual side effects a triple protostar system formed via fragmentation of a gravitationally unstable disk young stellar system caught in act of forming close multiples intricate tunnels in garnets from soils and river sediments in thailand possible endolithic microborings tiny tunnels inside garnets appear to be the result of boring microorganisms improving research impact through the use of media getting the world to listen improving the impact of research through storytelling germline mutations in sufu cause gorlin syndrome associated childhood medulloblastoma and redefine the risk associated with ptch mutations new cause of child brain tumor condition identified effect of automated online counseling on clinical outcomes and quality of life among adolescents with acne vulgaris internet acne education with automated counseling tested in clinical trial free space laser communication experiments from earth to the lunar reconnaissance orbiter in lunar orbit nasa beams mona lisa to lunar reconnaissance orbiter at the moon longitudinal effects of interoceptive awareness training through mindful awareness in body oriented therapy mabt as an adjunct to women s substance use disorder treatment a randomized controlled trial mindful body awareness training during treatment for drug addiction helps prevent relapse longer term effects of the angelina jolie effect increased risk reducing mastectomy rates in brca carriers and other high risk women breast cancer clinic attributes increased uptake of double mastectomies to angelina jolie effect two stage genome wide methylation profiling in childhood onset crohn s disease implicates epigenetic alterations at the vmp mir and hla loci epigenetic changes in children with crohn s disease seen in study breastfeeding practice oral contraceptive use and risk of rheumatoid arthritis among chinese women the guangzhou biobank cohort study breastfeeding associated with lower risk of rheumatoid arthritis according to new study semantic network analysis of vaccine sentiment in online social media child safety or parental duty new study maps out core concepts in the vaccination debate effect of intensive blood pressure lowering on left ventricular hypertrophy in patients with hypertension the systolic blood pressure intervention sprint trial intensive blood pressure can reduce risk of harm to heart muscle modified penetrance of coding variants by cis regulatory variation contributes to disease risk new study explains why genetic mutations cause disease in some people but not in others all you need is love evading hate speech detection hate speech detecting ais are fools for love projected asymmetric response of ad lie penguins to antarctic climate change penguin population could drop percent by end of the century directed differentiation of human pluripotent stem cells to blood brain barrier endothelial cells scientists create a recipe to make human blood brain barrier lasting effects of cancer and its treatment on employment and finances in adolescent and young adult cancer survivors for young adult cancer survivors debt and work related impairments methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value epigenetic signatures that differentiate triple negative breast cancers a scalable total synthesis of the antitumor agents et and lurbinectedin total synthesis of marine antitumor agents trabectedin and lurbinectedin bra wearing not associated with breast cancer risk a population based case control study no association found between wearing bra breast cancer microbial and metabolic alterations in gut microbiota of sows during pregnancy and lactation alternations in gut microbiota in pregnancy and lactation prevalence of eczema and food allergy is associated with latitude in australia lower levels of sunlight exposure link to allergy and eczema in children study suggests swine farming is a risk factor for infection with and high prevalence of carriage of multidrug resistant staphylococcus aureus swine farming a risk factor for drug resistant staph infections study finds uncertainty in modeled and observed climate change impacts on american midwest hydrology climate change s future impact uncertain on u.s. midwest water cycle prospectively assessed clinical outcomes in concussive blast vs nonblast traumatic brain injury among evacuated us military personnel in military personnel no difference between blast and nonblast related concussions methylation based biological age and breast cancer risk older biologic age linked to elevated breast cancer risk towards sustainable aquafeeds complete substitution of fish oil with marine microalga schizochytrium sp. improves growth and fatty acid deposition in juvenile nile tilapia oreochromis niloticus research team makes breakthrough toward fish free aquaculture feed fc receptor polymorphisms cetuximab therapy and survival in the ncic ctg co. trial of colorectal cancer blood marker determines who will respond to colorectal cancer drug newborn brain function is affected by fetal exposure to maternal serotonin reuptake inhibitors antidepressive treatment during pregnancy can affect newborn brain activity detection of microgauss coherent magnetic fields in a galaxy five billion years ago galaxy billion light years away shows we live in a magnetic universe intestinal gas capsules a proof of concept demonstration gut reaction smart pill smells out the body s fiber factor brain connectivity predicts placebo response across chronic pain clinical trials placebo sweet spot for pain relief identified in brain prevalence and predictors of major depressive disorder for fertility treatment patients and their partners fertility patients history is best predictor of risk for major depression early life exposure to ambient air pollution and childhood asthma in china kids living near major roads at higher risk of developmental delays resource selection and landscape change reveal mechanisms suppressing population recovery for the world s most endangered antelope decline of grass threatens world s most endangered antelope pregnancy imprints regulatory memory that sustains anergy to fetal antigen pregnancy generates maternal immune suppressive cells that protect the fetus motivational characteristics and resistance training in older adults a randomized controlled trial and year follow up resistance training and exercise motivation go hand in hand the activity in the anterior insulae is modulated by perceptual decision making difficulty difficult decisions involving perception increase activity in brain s insular cortex study finds diastolic blood pressure subclinical myocardial damage and cardiac events implications for blood pressure control doctors beware of low diastolic blood pressure when treating hypertension associations of cigarette smoking and polymorphisms in brain derived neurotrophic factor and catechol o methyltransferase with neurocognition in alcohol dependent individuals during early abstinence veterans are at higher risk of alcohol abuse relapse due to smoking effect of air quality on assisted human reproduction exposure to nitrogen dioxide lowers in vitro fertilization success a neuronal culture system to detect prion synaptotoxicity how prions kill neurons new culture system shows early toxicity to dendritic spines diminished capability to recognize the optimal temperature for sleep initiation may contribute to poor sleep in elderly people inability to detect changes in skin temperature may contribute to poor sleep of older adults acute health effects associated with exposure to volcanic air pollution vog from increased activity at kilauea volcano in mounting research shows increased health risks from volcanic air pollution total evidence phylogeny and evolutionary timescale for australian faunivorous marsupials dasyuromorphia cooling climate drove evolution of tasmanian devil and its relatives higher carbohydrate intake is associated with increased risk of all cause and disease specific mortality in head and neck cancer patients results from a prospective cohort study study explores carbohydrates impact on head neck cancers first year evaluation of mexico s tax on nonessential energy dense foods an observational study energy dense food consumption declines after mexico s tax metabolic reconfiguration supports reacquisition of primitive phenotype in human mesenchymal stem cell aggregates research points to ways to improve the therapeutic potential of stem cells extended effect of chronic social defeat stress in childhood on behaviors in adulthood chronic stress in early life causes anxiety aggression in adulthood neurobiologists find pm d is a quantitative trait locus associated with alzheimer s disease scientists discover a variation of the genome predisposing to alzheimer s disease response to acute concussive injury in soccer players is gender a modifying factor ? clinical article female athletes show no difference from males in neurocognitive testing after suffering sports related concussions neuronal stress pathway mediating a histone methyl phospho switch is required for herpes simplex virus reactivation discovery shows how herpes simplex virus reactivates in neurons to trigger disease prenatal and childhood exposure to phthalates and motor skills at age years prenatal exposure to phthalates linked to motor skill deficiencies at age prevalence practice patterns and evidence for chronic neck pain narcotics and diagnostics overused in treatment of chronic neck pain study finds ancient hydrothermal seafloor deposits in eridania basin on mars mars study yields clues to possible cradle of life evolutionary history and adaptation of a human pygmy population of flores island indonesia modern flores island pygmies show no genetic link to extinct hobbits increasing incidence of ischemic stroke in patients with hiv infection stroke rate rises for patients with hiv infection national trends in indicators of a medical home for children uninsured children most at risk for insufficient health care experiences osteopathic manipulative therapy in women with postpartum low back pain and disability a pragmatic randomized controlled trial osteopathic manipulative therapy significantly improves low back pain in postpartum women pathogenicity and vaccine efficacy of different clades of asian h n avian influenza a viruses in domestic ducks new vaccines protect against asian h n influenza a viruses in domestic ducks enhancing patient outcomes while containing costs after complex abdominal surgery a randomized controlled trial of the whipple accelerated recovery pathway warp effective method for reducing hospital stay after whipple operation who are the bosses ? group influence on the behavior of voles following owl attack leader of the pack study of voles and owls show rise of individuals with greatest influence on collective group behavior the epidemiology of vasospasm in children with moderate to severe traumatic brain injury researchers clarify vasospasm incidence in children with moderate to severe tbi impaired jip dependent axonal lysosome transport promotes amyloid plaque pathology role for lysosome transport in alzheimer s disease progression revealed effect of seasonal affective disorder and pathological tanning motives on efficacy of an appearance focused intervention to prevent skin cancer focusing on appearance may reduce tanning in young women identification of a highly neurotoxic synuclein species inducing mitochondrial damage and mitophagy in parkinson s disease culprit in parkinson s brain cell die off turbulent flow over craters on mars vorticity dynamics reveal aeolian excavation mechanism scientist s work may provide answer to martian mountain mystery successissomething to sneeze at influenza mortality in cities that participate in the super bowl super bowl celebrations spread flu according to researchers the origin and antiquity of syphilis revisited an appraisal of old world pre columbian evidence for treponemal infection skeletons point to columbus voyage for syphilis origins coordinated activation of wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration why hair turns gray communication between hair follicles and melanocyte stem cells key to mystery a global atlas of the dominant bacteria found in soil first global atlas of the bacteria living in your dirt a population based analysis of incentive payments to primary care physicians for the care of patients with complex disease physician incentive program to improve care for complex patients did not result in improvements core shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy nanoparticle drug cocktail could help treat lethal cancers gender differences in individual variation in academic grades fail to fit expected patterns for stem patterns in stem grades of girls versus boys increased wounding of southern right whale eubalaena australis calves by kelp gulls larus dominicanus at pen nsula vald s argentina southern right whale calf wounding by kelp gulls increased to nearly all over four decades proteomic evidence of dietary sources in ancient dental calculus research on british teeth unlocks potential for new insights into ancient diets occurrence and recurrence of attempted suicide among people with epilepsy new details on link between epilepsy and suicide attempt correlates of home range sizes of giraffes giraffa camelopardalis human settlements and rainfall affect giraffe home ranges transdifferentiation of parathyroid cells into cervical thymi promotes atypical t cell development researchers discover origin of unusual glands in the body integrative taxonomy of the plain backed thrush zoothera mollissima complex aves turdidae reveals cryptic species including a new species new species of bird discovered in india china by international team of scientists association between treatment for erectile dysfunction and death or cardiovascular outcomes after myocardial infarction impotence medicine associated with reduced long term risk of death after heart attack modulation of orthogonal body waves enables high maneuverability in sidewinding locomotion snake robots learn to turn by following the lead of real sidewinders a distributed experiment demonstrates widespread sodium limitation in grassland food webs insects crave salt and search grasslands for the limiting nutrient function of the nucleus accumbens in motor control during recovery after spinal cord injury motivation promotes recovery after spinal cord injury neuroscientific evidence structure of the immature hiv capsid in intact virus particles at. resolution first immature form of hiv seen at high resolution surprises researchers bayesian hierarchical models suggest oldest known plant visiting bat was omnivorous single tooth analysis of oldest known plant visiting bat fossil suggests it was omnivorous the fishing mantid predation on fish as a new adaptive strategy for praying mantids insecta mantodea two fishes a day keep the mantid coming back to prey the first fishing praying mantis the impact of compliance in posttreatment surveillance in head and neck squamous cell carcinoma impact of post treatment surveillance in head and neck squamous cell cancer radiosensitivity differences between liver metastases based on primary histology suggest implications for clinical outcomes following sbrt researchers discover liver metastases have different radiation sensitivities quantifying beetle mediated effects on gas fluxes from dung pats beetles modify emissions of greenhouse gases from cow pats trf is a stem cell marker and is essential for the generation of induced pluripotent stem cells new gene that is essential for nuclear reprogramming receptivity to television fast food restaurant marketing and obesity among u.s. youth study links youth obesity to tv fast food advertising environmental effects on compulsive tail chasing in dogs tail chasing in dogs resembles obsessive compulsive disorders in humans reduced myogenic and increased adipogenic differentiation capacity of rotator cuff muscle stem cells stem cells provide greater insight into rotator cuff disease sculpting and fusing biomimetic vesicle networks using optical tweezers optical tweezers mini tractor beams help arrange artificial cells into tissue structures clinical measures identify vitamin d deficiency in dialysis vitamin d deficiency likely among some kidney disease patients starting dialysis holocene climate variability in the levant from the dead sea pollen record drastic desertification researchers study dead sea climate past finding dramatic results vaccine adjuvants aluminum and monophosphoryl lipid a provide distinct signals to generate protective cytotoxic memory cd t cells adjuvant combo shows potential for universal influenza vaccine population and fertility by age and sex for countries and territories a systematic analysis for the global burden of disease study baby boom and bust nations rates of childbirth vary significantly rfx transcription factors are essential for hearing in mice scientists identify proteins crucial to loss of hearing forward genetics analysis of sleep in randomly mutagenized mice genetic analysis identifies proteins controlling sleep in mice southern hemisphere climate variability forced by northern hemisphere ice sheet topography north american ice sheet decay decreased climate variability in the southern hemisphere nonredundant function of soluble lt produced by innate lymphoid cells in intestinal homeostasis new insights into immune system of gastrointestinal tract a new golden frog species of the genus diasporus amphibia eleutherodactylidae from the cordillera central western panama new frog species from panama dyes fingers yellow identifying crowding stress tolerant hybrids in processing sweet corn new method of identifying sweet corn hybrids for increased yield and profit endocrine disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice fracking chemicals tied to reduced sperm count in mice a pilot randomized controlled trial of the effects of chair yoga on pain and physical function among community dwelling older adults with lower extremity osteoarthritis first study to show chair yoga as effective alternative treatment for osteoarthritis the first record of an alligator snapping turtle macrochelys temminckii in illinois in years first wild alligator snapping turtle in illinois since replicative fitness of transmitted hiv drives acute immune activation proviral load in memory cd t cells and disease progression fast replicating hiv strains drive inflammation and disease progression location of food stores near schools does not predict the weight status of maine high school students fast food restaurants have no impact on high school students weight maine study finds neuroanatomy of individual differences in language in adult males with autism presence or absence of early language delay alters anatomy of the brain in autism bispecific antibody affords complete post exposure protection of mice from both ebola zaire and sudan viruses experimental immunotherapy zaps two most lethal ebola virus strains effect of low intensity physical activity and moderate to high intensity physical exercise during adjuvant chemotherapy on physical fitness fatigue and chemotherapy completion rates results of the paces randomized clinical trial physical exercise helps women with breast cancer to better tolerate chemotherapy mental health on the go effects of a gamified attention bias modification mobile application in trait anxious adults mental health on the go reducing anxiety with smartphone app direct to consumer dna testing the fallout for individuals and their families unexpectedly learning of their donor conception origins growth in consumer dna testing brings new threat to those affected by donor conception warns expert earth as a hybrid planet the anthropocene in an evolutionary astrobiological context earth as hybrid planet new classification places anthropocene era in astrobiological context engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies engineering excitable cells for studies of bioelectricity and cell therapy structural and functional bases for broad spectrum neutralization of avian and human influenza a viruses lab made proteins neutralize multiple strains of seasonal and pandemic flu the protonation states of gtp and gppnhp in ras proteins researchers observe the switching of ras protein in detail ice loss from the east antarctic ice sheet during late pleistocene interglacials moderate warming could melt east antarctic ice sheet increased incidence rate of trauma and stressor related disorders in denmark after the september terrorist attacks in the united states impact on mental illness far beyond u.s. borders a review of remote sensing applications for oil palm studies remote sensing technologies key to the future of the oil palm industry radionuclides transform chemotherapeutics into phototherapeutics for precise treatment of disseminated cancer light triggered nanoparticles show promise against metastatic cancer long term trends of coral imports into the united states indicate future opportunities for ecosystem and societal benefits international trade in live corals could help preserve wild corals and coral reefs ecosystems study suggests empirical evidence for large x effects in animals with undifferentiated sex chromosomes sex with the other species tree frogs with foreign sex chromosomes are less fit informing canada s commitment to biodiversity conservation a science based framework to help guide protected areas designation through target and beyond location of protected areas vital to wildlife survival movement contingent time flow in virtual reality causes temporal recalibration temporal recalibration helping individuals shift perception of time misguided optimism among college student smokers leveraging their quit smoking strategies for smoking cessation campaigns smoking cessation research highlights importance of keeping teens from smoking social networking technologies as an emerging tool for hiv preventiona cluster randomized trial combination of social media behavior psychology leads to hiv testing better health behaviors divergence of ecosystem services in u.s. national forests and grasslands under a changing climate us national forests and grasslands could yield less water in future climate the mitochondrial disease patient s diagnostic odyssey results of a survey mitochondrial disease patients face difficult road to diagnosis the shared antibiotic resistome of soil bacteria and human pathogens human and soil bacteria swap antibiotic resistance genes do less harm evaluating hiv programmatic alternatives in response to cutbacks in foreign aid cutbacks in foreign aid for hiv treatment would produce great harm generate few savings quantifying unmet need in statin treated hyperlipidemia patients and the potential benefit of further ldl c reduction through an ehr based retrospective cohort study study shows one third of statin patients don t reach healthy levels of bad cholesterol impact of a large scale science intervention focused on english language learners science curriculum tailored to english language learners boosts student achievement an antimicrobial peptide regulates tumor associated macrophage trafficking via the chemokine receptor ccr a model for tumorigenesis dental researchers discover human beta defensin ignites in oral cancer growth gun possession among american youth a discovery based approach to understand gun violence multiple factors not just mental illness associated with gun possession violence among youths soy intake modifies the relation between urinary bisphenol a concentrations and pregnancy outcomes among women undergoing assisted reproduction eating soy may protect women from health risks of bpa innate immune processes are sufficient for driving silicosis in mice our lungs are innately prone to silicosis and related diseases new study suggests col a derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease new therapeutic avenue in the fight against chronic liver disease macrophage fatty acid synthase deficiency decreases diet induced atherosclerosis inhibiting fatty acids in immune cells decreases atherosclerosis risk adherence to biopsy guidelines increases celiac disease diagnosis low adherence to biopsy guidelines affects celiac disease diagnosis in the united states social behavioral deficits coincide with the onset of seizure susceptibility in mice lacking serotonin receptor c scientists identify key receptor as potential target for treatment of autism hiv related stigma affects cognition in older men living with hiv stigma impairs cognition in men living with hiv eat for life a work site feasibility study of a novel mindfulness based intuitive eating intervention non diet approach to weight management more effective in worksite wellness programs early and middle holocene hunter gatherer occupations in western amazonia the hidden shell middens hidden shell middens reveal ancient human presence in bolivian amazon children treated for lawn mower related injuries in us emergency departments lawn mower injuries send children to the emergency department every day irf transcription factor dependent cd b dendritic cells in human and mouse control mucosal il cytokine responses discovery of a new class of white blood cells uncovers target for better vaccine design single neuron activity and eye movements during human rem sleep and awake vision rapid eye movements in sleep reset dream snapshots in situ structural and microangiographic assessment of human skin lesions with high speed oct tissues tell the tale non invasive optical technique detects cancer by looking under the skin elevated glucocorticoid concentrations during gestation predict reduced reproductive success in subordinate female banded mongooses high stress during pregnancy decreases offspring survival according to mongoose study amyloid peptide protects against microbial infection in mouse and worm models of alzheimers disease human amyloid beta acts as natural antibiotic in the brain alzheimer s associated amyloid plaques may trap microbes long term follow up after phrenic nerve reconstruction for diaphragmatic paralysis a review of patients surgical repair of phrenic nerve injury improves breathing s proteasomes are rapidly activated by diverse hormones and physiological states that raise camp and cause rpn phosphorylation vigorous exercise fasting hormones improve elimination of toxic misfolded unnecessary proteins in mouse and human cells effect of human papillomavirus vaccination on cervical cancer screening in alberta hpv vaccine reduced cervical abnormalities in young women capelatus prykeigen. et sp.n. coleoptera dytiscidae copelatinae a phylogenetically isolated diving beetle from the western cape of south africa new species of diving beetle discovered in isolation in south africa policies to reduce influenza in the workplace impact assessments using an agent based model universal paid sick leave reduces spread of flu group allergen genes in two species of house dust mites dermatophagoides farinae and d. pteronyssinus acari pyroglyphidae direct sequencing characterization and polymorphism sharing that crowded holiday flight with countless hitchhiking dust mites a cost effectiveness analysis of nivolumab versus docetaxel for advanced nonsquamous nsclc including pd l testing nivolumab cost effectiveness improves by selecting non squamous nsclc pd l patients prevalence and correlates of screen based media use among youths with autism spectrum disorders adolescents with autism spend free time using solitary screen based media psychological therapies for the treatment of post traumatic stress disorder in children and adolescents psychological therapies improve life for children with post traumatic stress disorder study suggests early postnatal exposure to ultrafine particulate matter air pollution persistent ventriculomegaly neurochemical disruption and glial activation preferentially in male mice new evidence links air pollution to autism schizophrenia a variable stiffness tendril like soft robot based on reversible osmotic actuation the first tendril like soft robot able to climb direct measurements of oxygen gradients in spheroid culture system using electron parametric resonance oximetry non destructive technique measures oxygen levels in d cells used for toxicity testing functional neuroimaging evidence for distinct neurobiological pathways in attention deficit hyperactivity disorder brain imaging reveals adhd as a collection of different disorders a test of the senses fish select novel habitats by responding to multiple cues a test of the senses in the search for a shoal mate cold vapor generation beyond the input solar energy limit engineers upgrade ancient sun powered tech to purify water with near perfect efficiency the number of privately treated tuberculosis cases in india an estimation from drug sales data number of tuberculosis cases in india is double current estimates says new study associations of tm sf k allele with liver enzymes and lipid profile in children the panic study common gene mutation bad for liver values good for blood lipids in children a classification model for sensing human trust in machines using eeg and gsr new models sense human trust in smart machines a chemical genomic approach identifies matrix metallaoproteinases as playing an essential and specific role in xenopus melanophore migration skin color studies on tadpoles lead to cancer advance who drinks where youth selection of drinking contexts identifying how drinking contexts and youth characteristics change over time antiretroviral agents and prevention of malaria in hiv infected ugandan children hiv treatment reduces risk of malaria recurrence in children from gradual spreading to catastrophic collapse reconstruction of the ritter island volcanic sector collapse from high resolution d seismic data ritter island gives new insights into the dynamics of volcanic landslides characterization of circulating and endothelial progenitor cells in patients with extreme duration type diabetes high levels of cells involved in blood vessel repair in diabetics adaptable near infrared spectroscopy fiber array for improved coupling to different breast sizes during clinical mri researchers developing new approach for imaging dense breasts for abnormalities characteristics and prognosis of ischemic stroke in young cannabis users compared with non cannabis users researchers study differences in ischemic stroke in marijuana users preparing for medical emergencies the essential drugs and equipment for the dental office new emergency preparedness information available for dental offices nonlinear relationship between birth weight and visceral fat in adolescents low and high birthweight babies appear at increased risk for cardiovascular disease effects of inorganic nutrients and organic matter on microbial euendolithic community composition and microbioerosion rates microbes sponges and worms add to coral reef woes simulated shift work disrupts maternal circadian rhythms and metabolism and increases gestation length in sheep shift work for mothers associated with reduced fetal growth and longer pregnancies facilitating wolbachia introductions into mosquito populations through insecticide resistance selection fighting disease from within the mosquito new techniques to help halt the spread of disease task differences and prosociality investigating pet dogs prosocial preferences in a token choice paradigm dogs share food with other dogs even in complex situations bicycle trauma injuries and hospital admissions in the united states increase seen in bicycle related injuries hospital admissions in united states human blood tfr cells are indicators of ongoing humoral activity not fully licensed with suppressive function specific type of immune regulatory cells could be used as potential clinical biomarkers to diagnose certain autoimmune diseases the growth of private label brands a worldwide phenomenon ? international marketing are store brands becoming a global phenomenon ? effects of abaloparatide sc on fractures and bone mineral density in subgroups of postmenopausal women with osteoporosis and varying baseline risk factors abaloparatide benefits a wide range of postmenopausal women with osteoporosis controlled release of chlorhexidine from a mesoporous silica containing macroporous titanium dental implant prevents microbial biofilm formation new dental implant with built in reservoir reduces risk of infections first drink to first drunk age of onset and delay to intoxication are associated with adolescent alcohol use and binge drinking first drink to first drunk connection between early age of first drink heavy drinking sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction eosinophils as markers for asthma largest scale study so far on asthma genetics sheds light on disease mechanisms the potential of graphene as an ito replacement in organic solar cells an optical perspective graphene sees the light sheets of carbon just one atom thick could be used in photovoltaic cells children with asd can use gaze to map new words children with autism learn new words much like others do study finds precision health care efficiency via accountable care organizations pioneer aco program sees modest reduction in low value services pacemaker and plateau potentials shape output of a developing locomotor network unique spinal nerve cell activity novel forms of activity linked to development of motor behaviors such as swimming statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease cholesterol lowering drug shows promise against serious infections in sickle cell disease infant mortality and subsequent risk of stillbirth a retrospective cohort study infant mortality linked to subsequent risk of stillbirth new u.s. study finds explaining the origin of fluting in north american pleistocene weaponry archaeologist explains innovation of fluting ancient stone weaponry physiologic frailty in nonelderly hematopoietic cell transplantation patients results from the bone marrow transplant survivor study frailty among young bone marrow transplant survivors increases risk of death a late ordovician planktic assemblage with exceptionally preserved soft bodied problematica from the martinsburg formation pennsylvania rare million year old cone shaped fossil discovery f fdg as an inflammation biomarker for imaging dengue virus infection and treatment response novel approach to seeing dengue infection in the body butterfly mortality and salvage logging from the march storm in the monarch butterfly biosphere reserve in mexico damage to monarch butterfly colonies in storm worse than thought rates of major depressive disorder and clinical outcomes following traumatic brain injury high prevalence of depression after traumatic brain injury study finds modifiers of cancer risk in brca and brca mutation carriers systematic review and meta analysis heredity is not destiny breastfeeding birth control pills may reduce ovarian cancer risk among women with brca gene mutations role of the acid site for selective catalytic oxidation of nh over au nb o breakthrough in air purification with a catalyst that works at room temperature fall in genital warts diagnoses in the general and indigenous australian population following implementation of a national human papillomavirus vaccination program analysis of routinely collected national hospital data hpv vaccine could close the gap on australian indigenous health evaluation of a multi functional nanocarrier for targeted breast cancer inos gene therapy nanomedicine gene fuelled transporter causes breast cancer cells to self destruct canine distemper virus an emerging disease in wild endangered amur tigers panthera tigris altaica canine distemper virus an emerging disease in rare amur tigers inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma new drug candidates reverse drug resistance in multiple myeloma in preclinical models public attitudes toward larger cigarette pack warnings results from a nationally representative u.s. sample broad support exists for larger warnings on cigarette packs theories of practice and public health understanding un healthy practices more public health interventions required to tackle grim reaper of lifestyle diseases quantitative trait loci for water use efficiency in barley hordeum vulgare l. measured by carbon isotope discrimination under rain fed conditions on the canadian prairies building better barley improving selection efficiency for more water efficient varieties the relationships between democratic experience adult health and cause specific mortality in countries between and an observational analysis democracy linked to global health gains in low middle income countries significant reduction of antibiotic use in the community after a nationwide campaign in france public health campaign associated with major reduction in antibiotic use oxidation of kcnb channels in the human brain and in mouse model of alzheimer s disease possible cause for alzheimer s and traumatic brain injury discovered altered relaxation times in mri indicate bronchopulmonary dysplasia specific identification of chronic lung disease in premature babies glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells sugar mimics guide stem cells toward neural fate nanostructured fibers as a versatile photonic platform radiative cooling and waveguiding through transverse anderson localization researchers mimic comet moth s silk fibers to make air conditioned fabric greenhouse gas emissions and energy use associated with production of individual self selected us diets percent of americans responsible for almost half of us food related greenhouse gas emissions a broadband achromatic polarization insensitive metalens consisting of anisotropic nanostructures broadband achromatic metalens focuses light regardless of polarization recognition of earthquake prone areas m. in the iberian peninsula new areas prone to moderate earthquakes identified in iberian peninsula effectiveness of a selective personality targeted prevention program for adolescent alcohol use and misuse a cluster randomized controlled trial teenagers avoid early alcohol misuse through personality management wheat yield loss attributable to heat waves drought and water excess at the global national and subnational scales extreme weather conditions and climate change account for of global wheat production variability climatically driven changes in primary production propagate through trophic levels nasa satellites assist states in estimating abundance of key wildlife species evaluation of risk for late language emergence after in utero antiretroviral drug exposure in hiv exposed uninfected infants prenatal anti hiv meds not linked to children s language delays oocyte and sperm donors opinions on the acceptable number of offspring sperm egg donors comfortable assisting with betweeen one and childen swedish study finds reproductive tract tumours the scourge of woman reproduction ails indian rhinoceroses indian rhinoceroses reproductive tract tumors reduce female fertility in early stages tissue engineered skin containing mesenchymal stem cells improves burn wounds bone marrow stem cells used to regenerate skin variation in the ratio of physician charges to medicare payments by specialty and geographic region patients face surprise medical bills from out of network specialists self regulation of emotional responses to zika spiral of fear suppressing negative emotions during health scare may whip up spiral of fear toy based technologies for children with disabilities simultaneously supporting self directed mobility participation and function a tech report new modified toy car designs offer children with disabilities more options efficient identification of mutated cancer antigens recognized by t cells associated with durable tumor regressions cancer mutations identified as targets of effective melanoma immunotherapy outpatient glycemic control with a bionic pancreas in type diabetes bionic pancreas controls blood sugar levels in adults adolescents with type diabetes proteomics and transcriptomics investigation on longissimus muscles in large white and casertana pig breeds sows ears and silk purses packing more flavor into modern pork pleiotrophin regulates the retention and self renewal of hematopoietic stem cells in the bone marrow vascular niche potent growth factor for blood stem cells identified meta analyses of genome wide association studies identify multiple loci associated with pulmonary function potential genetic links to lung disease risk uncovered comparative effectiveness of regional versus general anesthesia for hip fracture surgery in adults regional anesthesia reduces complications and death for hip fracture patients a gas chromatography mass spectrometry method for the quantitation of n nitrosoproline and n acetyl s allylcysteine in human urine application to a study of the effects of garlic consumption on nitrosation new testing method hints at garlic s cancer fighting potential duration and life stage of antibiotic use and risk of cardiovascular events in women antibiotic use linked to greater risk of heart attack and stroke in women opioid independent and opioid mediated modes of pain modulation mental imagery manages pain independent of opioid system cortical cholinergic denervation in primary progressive aphasia with alzheimer pathology alzheimer s treatment holds promise for primary progressive aphasia patients the causal role of cigarette smoking in bladder cancer initiation and progression and the role of urologists in smoking cessation patients unaware of link between smoking and bladder cancer associations of housing mobility interventions for children in high poverty neighborhoods with subsequent mental disorders during adolescence moving out of high poverty appears to affect the mental health of boys girls differently a substantial and unexpected enhancement of motion perception in autism enhanced motion perception in autism may point to an underlying cause of the disorder conflict between groups promotes later defence of a critical resource in a cooperatively breeding bird bird battles promote unity on the front line screening and selection of high carotenoid producing in vitro tomato cell culture lines for c carotenoid production scientists develop tool to trace metabolism of cancer fighting tomato compounds longitudinal impact of substance use and depressive symptoms on bone accrual among girls aged years smoking and depressive symptoms in adolescent girls are red flag for postmenopausal osteoporosis crystal structure and equation of state of fe si alloys at super earth core conditions ultrahigh pressure laser experiments shed light on super earth cores long term complications of hand assisted versus laparoscopic colectomy helping hand of hybrid surgery benefits colorectal patients ending the hiv epidemic in the united states closing the implementation gaps closing treatment gaps critical to ending the u.s. hiv epidemic experts say impact of statin media coverage on the use of statins in the uk an interrupted time series analysis using primary care data statins controversy linked to rise in uk patients stopping the treatment a new species of earth snake dipsadidae geophis from mexico the aztec treasure unearthed new earth snake species discovered in mexico dopamine neurons mediate learning and forgetting through bidirectional modulation of a memory trace scientists decode mechanism of remembering and forgetting in fruit flies antarctic ice shelf calving triggered by the honshu japan earthquake and tsunami march japan s tohoku tsunami created icebergs in antarctica potential impact of amantadine on aggression in chronic traumatic brain injury new treatment option discovered for brain injury patients suffering from aggression collagen degradation and mmp activation by enterococcus faecalis contribute to intestinal anastomotic leak in late post surgical colon leaks finger points to microbes fitness trade offs associated with the evolution of resistance to antifungal drug combinations drug combinations a good approach for infectious fungus research shows using residential segregation to predict colorectal cancer stage at diagnosis two different approaches place matters in late diagnosis of colorectal cancer study finds competitive fitness of a predominant pelagic calcifier impaired by ocean acidification how community interactions amplify response of calcifying phytoplankton species to ocean acidification experimental treatment of ebola virus disease with tkm a single arm phase clinical trial clinical trial for experimental ebola drug publishes results intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles nonsmokers in automobiles are exposed to significant secondhand smoke emergence of multi body interactions in a fermionic lattice clock signs of interactive form of quantum matter observed pet dog ownership decisions for parents of children with autism spectrum disorder dog ownership benefits families of children with autism tdp repression of nonconserved cryptic exons is compromised in als ftd scientists report explanation for protein clumps in brain cells of patients with als molecular characterization of basal like and non basal like triple negative breast cancers researchers discover biological diversity in triple negative breast cancer concussion and football failures to respond by the nfl and the medical profession health and law expert nfl not alone in handling concussions as benign problems early life experience drives structural variation of neural genomes in mice early life experiences influence dna in the adult brain genetic determinants of the gut microbiome in uk twins twin study finds that gut microbiomes run in families plio pleistocene climate sensitivity evaluated using high resolution co records evidence from warm past confirms recent ipcc estimates of climate sensitivity the nap motif of activity dependent neuroprotective protein adnp regulates dendritic spines through microtubule end binding proteins new molecular target key to enhanced brain plasticity influence of phosphoproteins biomimetic analogs on remineralization of mineral depleted resin dentin interfaces created with ion releasing resin based systems revolutionary therapeutic dental adhesives with the aptitude to remineralize the resin dentine bonding interface through biomimetic processes the pediatric cell atlas defining the growth phase of human development at single cell resolution pediatric cell atlas will map single cell changes for a deeper view of child health and disease historical contingency in a multigene family facilitates adaptive evolution of toxin resistance one snake s prey is another s poison scientists pinpoint genetics of extreme resistance synthetic biology approach for plant protection using dsrna a vaccine for edible plants ? a new plant protection method on the horizon baseline neuropsychological testing in managing sport related concussion does it modify risk ? does baseline concussion testing really reduce risks to athletes ? subarctic singers humpback whale megaptera novaeangliae song structure and progression from an icelandic feeding ground during winter humpback whales songs at subarctic feeding areas are complex progressive probiotics to prevent or treat excessive infant crying study examines probiotics to prevent or treat excessive infant crying fire history in a western fennoscandian boreal forest as influenced by human land use and climate tree scars record years of natural and cultural fire history in a northern forest the genome sequence of a widespread apex predator the golden eagle aquila chrysaetos genome yields insights into golden eagle vision smell sunlight exposure and cutaneous human papillomavirus seroreactivity in basal cell and squamous cell carcinomas of the skin sun exposure and cutaneous hpv infection found synergistic in skin cancers therapeutic hemoglobin levels after gene transfer in thalassemia mice and in hematopoietic cells of thalassemia and sickle cells disease patients new gene therapy approach developed for red blood cell disorders associations of dispositional mindfulness with obesity and central adiposity the new england family study inherent mindfulness linked to lower obesity risk belly fat estimated health benefits of exhaust free transport in the city of malm southern sweden the health effect of air pollution from traffic changes of the human gut microbiome induced by a fermented milk product impact on gut microbiota of fermented milk product containing probiotics revealed by new technology numerical modeling of initiation and propagation of corrosion in hollow submerged marine concrete structures macrocells influence corrosion rate of submerged marine concrete structures nudging students toward healthier food choices applying insights from behavioral economics suggestions for nudging children toward healthier food choices effects of social and extra pair mating on sexual selection in blue tits cyanistes caeruleus evolutionary consequences of infidelity in birds can extra pair relationships give rise to sexual dimorphism ? forever in the dark the cave dwelling azooxanthellate reef coral leptoseris troglodyta sp. n. scleractinia agariciidae new cave dwelling reef coral discovered in the indo pacific mass loss of totten and moscow university glaciers east antarctica using regionally optimized grace mascons glaciers in east antarctica also imperiled by climate change dimensions of physical punishment and their associations with children s cognitive performance and school adjustment physical abuse and punishment impact children s academic performance association between elevated brain amyloid and subsequent cognitive decline among cognitively normal persons elevated brain amyloid level associated with increased likelihood of cognitive decline monitoring single cell gene regulation under dynamically controllable conditions with integrated microfluidics and software lab on a chip for tracking single bacterial cells oxantel disrupts polymicrobial biofilm development of periodontal pathogens drug may guard against periodontitis related chronic diseases intracellular sers nanoprobes for distinction of different neuronal cell types gold nanoprobes hold the key to treating killer diseases serum biomarker signature based liquid biopsy for diagnosis of early stage pancreatic cancer new blood test detects early stage pancreatic cancer exogenous tnfr activation protects from acute gvhd via host t reg cell expansion researchers develop new strategy to limit side effects of stem cell transplants hepatocyte secreted dpp in obesity promotes adipose inflammation and insulin resistance belly fat promotes diabetes under orders from liver single dose gene replacement therapy for spinal muscular atrophy encouraging data for gene replacement therapy for sma type i phase study shows sailing injury and illness results of an online survey watch out for that boom with the america s cup destination decided timely study identifies sailing injuries monitoring fast voxel scale cure kinetics via sample coupled resonance photorheology new nist method measures d polymer processing precisely an in vitro paradigm to assess potential anti a antibodies for alzheimer s disease advancing the search for antibodies to treat alzheimer s disease medial ganglionic eminence like cells derived from human embryonic stem cells correct learning and memory deficits stem cell transplant restores memory learning in mice inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease a systematic review and meta analysis popular copd treatment increases risk for cardiac events cardiac death bone management in hematologic stem cell transplant recipients strategies to protect bone health in hematologic stem cell transplant recipients neuronal human bace knockin induces systemic diabetes in mice new link found between diabetes alzheimer s disease a randomized controlled trial of parent child psychotherapy targeting emotion development for early childhood depression parent child therapy helps young children with depression manuscript maps that imitate printed maps some examples in early spanish american cartography hand drawn maps imitating the printed maps in the st days of hispano american cartography seite articles page of original article inflammatory bowel disease in pediatric patients characteristics of newly diagnosed patients from the cedata gpge registry chronic bowel inflammation is diagnosed too late in children adolescents behavioral plasticity in larval reef fish orientation is influenced by recent acoustic experiences human noise pollution in ocean can lead fish away from good habitats and off to their death perioperative outcomes of adolescents undergoing bariatric surgery the teen longitudinal assessment of bariatric surgery teen labs study no major complications in most teens undergoing weight loss bariatric surgery study suggests amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in app ps transgenic mice compounded outcomes associated with comorbid alzheimer s disease cerebrovascular disease can gay and lesbian parents promote healthy development in high risk children adopted from foster care ? foster kids do equally well when adopted by gay lesbian or heterosexual parents study suggests plasma mirna profiles in pregnant women predict infant outcomes following prenatal alcohol exposure blood test may help identify fetal alcohol spectrum disorders the role of the physician when a patient discloses intimate partner violence perpetration a literature review what is the role of the physician when a patient discloses intimate partner violence perpetration ? increased maternal fat consumption during pregnancy alters body composition in neonatal mice moms who eat high fat diet before during pregnancy program babies to be fat at risk mouse study shows insights into the pathogenesis of anaplastic large cell lymphoma through genome wide dna methylation profiling epigenetics provides new insights into the pathogenesis of lymphoma survival of mutyh associated polyposis patients with colorectal cancer and matched control colorectal cancer patients colorectal cancer survival advantage in mutyh associated polyposis hoxb is an er cofactor in the activation of her and multiple er target genes leading to endocrine resistance molecular feedback loop may explain tamoxifen resistance in patients with breast cancer parental obesity and risk of autism spectrum disorder parental obesity and autism risk in the child is paternal obesity a greater risk factor than maternal obesity ? inhibition of mitochondrial protein import by mutant huntingtin fatal cellular malfunction identified in huntington s disease variable expression of pik r and pten in ewing sarcoma impacts oncogenic phenotypes serendipity leads to discovery of adult cancer genes driving young adult ewing sarcoma gas phase chemistry of cool exoplanet atmospheres insight from laboratory simulations alien imposters planets with oxygen don t necessarily have life probing backbone hydrogen bonding in pdz ligand interactions by protein amide to ester mutations designer proteins provide new information about body s signal processes sea level and salinity fluctuations during the paleocene eocene thermal maximum in arctic spitsbergen arctic environment during an ancient bout of natural global warming engineered hybrid spider silk particles as delivery system for peptide vaccines a new kind of vaccine based on spider silk ankle injury prevention programs for soccer athletes are protective a level i meta analysis prevention programs significantly reduce ankle injuries in soccer athletes management of diabetes and associated cardiovascular risk factors in seven countries a comparison of data from national health examination surveys diabetics in the us six other countries ineffectively treated for diabetes and related risk factors water velocity tolerance in tadpoles of the foothill yellow legged frog rana boylii swimming performance growth and survival foothill yellow legged frog provides insight on river management a second contender for world s smallest fly diptera phoridae new big armed fly species named after former california governor arnold schwarzenegger large scale meta analysis characterizes genetic architecture for common psoriasis associated variants largest psoriasis meta analysis to date yields new genetic clues medical student attitudes toward video games and related new media technologies in medical education medical students open to learning with video games structural basis for nutrient acquisition by dominant members of the human gut microbiota new light shed on functioning of human gut bacteria job strain and atrial fibrillation results from the swedish longitudinal occupational survey of health and meta analysis of three studies stressful jobs are associated with a higher risk of heart rhythm disorders density of surgeons is significantly associated with reduced risk of deaths from motor vehicle crashes in us counties surgeon availability tied to survival rate in vehicle crashes altered modes of stem cell division drive adaptive intestinal growth intestinal stem cells respond to food by supersizing the gut economic evaluation of the removal of tobacco promotional displays in ireland tobacco out of sight out of mind ? first direct detection of an exoplanet by optical interferometry. astrometry and k band spectroscopy of hr e gravity instrument breaks new ground in exoplanet imaging low childhood nature exposure is associated with worse mental health in adulthood contact with nature during childhood could lead to better mental health in adulthood brain derived neurotrophic factor val met genotype and ovarian steroids interactively modulate working memory related hippocampal function in women a multimodal neuroimaging study estrogen alters memory circuit function in women with gene variant therapeutic activity of an anti idiotypic antibody derived killer peptide against influenza a virus experimental infection killer peptide may offer new therapy against influenza a virus association between influenza vaccination and cardiovascular outcomes in high risk patientsa meta analysis flu vaccine associated with lower risk of cardiovascular events trends in causes of death in low mortality countries implications for mortality projections new study from population and development review finds flaws in mortality projections what enrollees think of medicaid results from a national survey of patient satisfaction medicaid enrollees satisfied with coverage physician access survey finds increased risk of postoperative deep vein thrombosis and pulmonary embolism in patients with inflammatory bowel disease a study of national surgical quality improvement program patients patients with inflammatory bowel disease appear to be at increased risk for developing post operative deep vein thrombosis and pulmonary embolism subclinical cytomegalovirus infection is associated with altered host immunity gut microbiota and vaccine responses quiet viruses alter body s response to vaccines pathogens caenorhabditis elegans oocytes detect meiotic errors in the absence of canonical end on kinetochore attachments new insights into leading cause of miscarriage birth defects discovered bdnf trkb content and interaction with gastrin releasing peptide receptor blockade in colorectal cancer a potential novel drug target for colorectal cancer treatment comes from the brain stabilized imaging of immune surveillance in the mouse lung new imaging advance illuminates immune response in breathing lung a rvi lai reference curve to detect n stress and guide n fertigation using combined information from spectral reflectance and leaf area measurements in potato hitting the bull s eye on crop nutrient requirements broad neutralization coverage of hiv by multiple highly potent antibodies aids researchers isolate new potent and broadly effective antibodies against hiv early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of huntington s disease huntington s disease linked to dysfunction of brain structure inactivation of a crf dependent amygdalofugal pathway reverses addiction like behaviors in alcohol dependent rats scientists hunt down the brain circuit responsible for alcohol cravings postoperative statin use and risk of biochemical recurrence following radical prostatectomy results from the search database statin use associated with reduced risk of prostate cancer recurrence porewater salinity reveals past lake level changes in lake van the earth s largest soda lake porewater salinity key to reconstructing years of lake van s history global regional and national comparative risk assessment of behavioural environmental and occupational and metabolic risks or clusters of risks in countries a systematic analysis for the global burden of disease study poor diet and high blood pressure now number one risk factors for early death safe administration of the seasonal trivalent influenza vaccine to children with severe egg allergy children with egg allergies can safely receive flu vaccine multi center study finds foreskin surface area and hiv acquisition in rakai uganda size matters foreskin surface area and hiv acquisition size matters single cell bioluminescence imaging of deep tissue in freely moving animals in living color seeing cells from outside the body with synthetic bioluminescence botulinum toxin a for prophylactic treatment of migraine and tension headaches in adults a meta analysis botox injections associated with only modest benefit for chronic migraine and daily headaches single shot single gate rf spin readout in silicon quantum computing at scale scientists achieve compact sensitive qubit readout the antagonistic modulation of arp activity by n wasp wave and pick defines dynamic changes in astrocyte morphology key target responsible for triggering detrimental effects in brain trauma identified the non native royal damsel neopomacentrus cyanomos in the southern gulf of mexico an invasion risk ? potential invasive species identified in s. gulf of mexico both the private option and traditional medicaid expansions improved access to care for low income adults traditional medicaid expansion and private option both improve access to health care efficient ph gradient enabled microscale bipolar interfaces in direct borohydride fuel cells high powered fuel cell boosts electric powered submersibles drones selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in hiv broadly neutralizing antibodies new insight on potent hiv antibody could improve vaccine design low serum vitamin d levels and recurrent inflammatory spinal cord disease low vitamin d levels may be associated with recurrent inflammatory spinal cord disease il receptor antagonist therapy mitigates placental dysfunction and perinatal injury following zika virus infection rheumatoid arthritis drug diminishes zika birth defects in mice risks associated with obesity in pregnancy for the mother and baby a systematic review of reviews increased risks in pregnancy for obese mothers and their babies says study noninvasive cardiac radiation for ablation of ventricular tachycardia deadly heart rhythm halted by noninvasive radiation therapy a genetic switch for worker nutrition mediated traits in honeybees two step path to shrinking worker bee gonads climate change and coral reef bleaching an ecological assessment of long term impacts recovery trends and future outlook long term recovery of reefs from bleaching requires local action to increase resilience chemical transfer of dissolved organic matter from surface seawater to sea spray water soluble organic aerosol in the marine atmosphere new insight into ocean atmosphere interaction and subsequent cloud formation differentiating dietary and non dietary microfossils extracted from human dental calculus the importance of sweet potato to ancient diet on rapa nui dental plaque reveals key plant in prehistoric easter island diet lipolysis stimulated lipoprotein receptor lsr is the host receptor for the binary toxin clostridium difficile transferase cdt poisonous effect of intestinal bacteria explained researchers identify site of action of cytotoxin produced by hypervirulent intestinal flora prediction model for aneuploidy in early human embryo development revealed by single cell analysis discovery could improve in vitro fertilization success rates for women around the world variable manifestations diverse seroreactivity and post treatment persistence in non human primates exposed to borrelia burgdorferi by tick feeding lyme bacteria survive day course of antibiotics months after infection assessing synaptic density in alzheimer disease with synaptic vesicle glycoprotein a positron emission tomographic imaging test for alzheimer s disease directly measures synaptic loss canine retina has a primate fovea like bouquet of cone photoreceptors which is affected by inherited macular degenerations new structure in dogs eye linked to blinding retinal diseases population level antibody estimates to novel influenza a h n low population immunity to new bird flu virus h n in humans stock chatter using stock sentiment to predict price direction stock prognosticators finance message board users may be able to predict stock price movements particle depletion does not remediate acute effects of traffic related air pollution and allergen a randomized double blinded crossover study diesel exhaust filtered of its tiny particles may worsen allergy induced lung impairment a sequence polymorphism in mstn predicts sprinting ability and racing stamina in thoroughbred horses genetic test for speed gene in thoroughbred horses do community based patient assistance programs affect the treatment and well being of patients with breast cancer ? value limitations of patient assistance programs for women with breast cancer essential oils and their components are a class of antifungals with potent vapour phase mediated anti candida activity plant derived volatiles may serve as future antifungals adjuvant radiotherapy and survival for patients with node positive head and neck cancer an analysis by primary site and nodal stage combining radiation and surgery significantly improves survival for head and neck cancer patients association of perivascular localization of aquaporin with cognition and alzheimer disease in aging brains possible new target for treating and preventing alzheimer s triple negative breast cancer risk genes identified by multigene hereditary cancer panel testing triple negative genes associated with risk for aggressive breast cancer does hunting or hiking affect wildlife communities in protected areas ? hiking hunting has minor effects on mammals in protected eastern forests two year follow up of internet and telephone assisted parent training for disruptive behavior at age internet and telephone assisted training for child disruptive behavior found to be effective development of novel dna encoded pcsk monoclonal antibodies as lipid lowering therapeutics engineered dna encoded pcsk inhibitors may provide an effective alternative for treating high cholesterol paternal kin recognition in the high frequency ultrasonic range in a solitary foraging mammal how in the animal world a daughter avoids mating with her father paternal voice recognition discovering innovative therapies for rare tumors combining genetically accurate disease models with in silico analysis to identify novel therapeutic targets stem cells may speed up screening of drugs for rare cancers type diabetes defined by severe insulin deficiency occurs after years of age and is commonly treated as type diabetes a third of type diabetes is misdiagnosed in the over s long term quit rates after a perioperative smoking cessation randomized controlled trial one year later preoperative quit smoking program still shows benefits in vivo suppression of hiv rebound by didehydro cortistatin a a block and lock strategy for hiv treatment new research opens the door to functional cure for hiv chronic pain opioid prescriptions and mortality in denmark a population based cohort study legally prescribed opioid use may increase mortality in chronic pain patients cdkn b p is localized in mitochondria and improves respiration dependent processes in the cardiovascular system new mode of action for caffeine caffeine from four cups of coffee protects the heart with the help of mitochondria the role of electron electron interactions in two dimensional dirac fermions scientists solve open theoretical problem on electron interactions do metropolitan hiv epidemic histories and programs for people who inject drugs and men who have sex with men predict aids incidence and mortality among heterosexuals ? reducing hiv transmission among drug injectors lowers aids mortality in heterosexuals cued recall of alcohol advertising on television and underage drinking behavior alcohol ads on tv associated with drinking behavior in young people sleep efficiency but not sleep duration of healthy school age children is associated with grades in math and languages all in a good night s sleep how quality of sleep impacts academic performance in children bubble cascade in guinness beer is caused by gravity current instability mystery of texture of guinness beer inclination angle of a pint glass is key to solution smoking and weight change after new health diagnoses in older adults new diagnoses may provide window of opportunity for health behavior change hearing through your eyes neural basis of audiovisual cross activation revealed by transcranial alternating current stimulation people hear flashes due to disinhibited flow of signals around the brain suggests study plant and animal glycolate oxidases have a common eukaryotic ancestor and convergently duplicated to evolve long chain hydroxy acid oxidases metabolism gives boost to understanding plant animal nutrient evolution formoterol a long acting adrenergic agonist improves cognitive function and promotes dendritic complexity in a mouse model of down syndrome drug improves cognitive function in mouse model of down syndrome the health impact of air pollution and outdoor physical activity on children and adolescents in mainland china air pollution and lack of physical activity pose competing threats to children in china genome wide association studies of brain structure and function in the uk biobank genetics of brain structure and description of largest human genetic study common variants at q. predispose to migraine in african american children gene variants raise risk of migraines in african american children shared decision making in acute surgical illness the surgeon s perspective under pressure the surgeon s conundrum in decision making photon only molecular motor with reverse temperature dependent efficiency molecular motors chemical carousel rotates in the cold the impact of the world trade center attack on fdny firefighter retirement disabilities and pension benefits world trade center attacks increased subsequent firefighter retirements study finds continuous radar tracking illustrates the development of multi destination routes of bumblebees radar tracking reveals how bees develop a route between flowers acceleration of electrons in the plasma wakefield of a proton bunch scientists achieve first ever acceleration of electrons in plasma waves optimal timing of antiretroviral therapy initiation for hiv infected adults with newly diagnosed pulmonary tuberculosis early hiv treatment improves survival in some patients with newly diagnosed tb a photobleaching resistant polymer supported hexanuclear molybdenum iodide cluster for photocatalytic oxygenations and photodynamic inactivation of staphylococcus aureus new material in the fight against hospital acquired infections high fidelity patch clamp recordings from neurons cultured on a polymer microchip neurochip technology developed advances to further brain research of diseases such as alzheimer s and parkinson s first japanese record of heteropriapulus heterotylus monogenea dactylogyridae from the alien catfish pterygoplichthys disjunctivus siluriformes loricariidae in okinawa promoting parasites researchers quest to identify freshwater fish parasites in japan effect of mno crystal structure on aerobic oxidation of hydroxymethylfurfural to furandicarboxylic acid green catalysts with earth abundant metals accelerate production of bio based plastic particle acceleration model for the broad band baseline spectrum of the crab nebula stellar corpse sheds light on origin of cosmic rays increased ceramide content and nf b signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males. fat molecule ceramide may factor in muscle loss in older adults the effect of sediment mixing on mercury dynamics in two intertidal mudflats at great bay estuary new hampshire usa new research sheds light on mercury pollution in estuaries food chain breast cancer amongst filipino migrants a review of the literature and ten year institutional analysis filipino newcomers to canada diagnosed with breast cancer at a younger age genome wide association study for anthracycline induced congestive heart failure genetic biomarker ids patients with increased risk for heart damage by anthracycline chemo a population of luminous accreting black holes with hidden mergers astronomers find pairs of black holes at the centers of merging galaxies changes in cortical sensitivity to infant facial cues from pregnancy to motherhood predict mother infant bonding mothers whose responses to infants facial cues increase report stronger bonds with babies interpersonal violence at playa venado panama ad a reevaluation of the evidence violence in pre columbian panama exaggerated new study shows a small molecule trkb ligand restores hippocampal synaptic plasticity and object location memory in rett syndrome mice drug improves brain performance in rett syndrome mice surface features of recombinant spider silk protein eadf made materials are well suited for cardiac tissue engineering spider silk protein may be useful for engineering artificial cardiac tissue differences between sexes in lower extremity alignment and muscle activation during soccer kick you kick like a girl men and women use different leg and hip muscles during soccer kick machine learning reveals protein signatures in csf and plasma fluids of clinical value for als promising proteins for diagnostic prognostic use in als tgf associated extracellular matrix genes link cancer associated fibroblasts to immune evasion and immunotherapy failure gene signature discovery may predict response to immune therapy host derived nitrate boosts growth of e. coli in the inflamed gut scientists find key to growth of bad bacteria in inflammatory bowel disease mortality risk and survival in the aftermath of the medieval black death new study sheds light on survivors of the black death improved photovoltaic performance from inorganic perovskite oxide thin films with mixed crystal phases high efficiency solar power conversion allowed by a novel composite material gut microbiota of healthy canadian infants profiles by mode of delivery and infant diet at months infant gut microbiota influenced by cesarean section and breastfeeding practices may impact long term health soil properties affect pinyon pine juniper response to drought dying trees in southwest set stage for erosion water loss in colorado river legislators sources of behavioral health research and preferences for dissemination variations by political party three quarters of u.s. lawmakers don t look to university scientists for behavioral health research cassini ring seismology as a probe of saturn s interior. i. rigid rotation waves in saturn s rings give precise measurement of planet s rotation rate realizing large scale electronic grade two dimensional semiconductors scalable two dimensional materials advance future gen electronics physiological daily inhalation rates for health risk assessment in overweight obese children adults and elderly overweight or obese people breathe more air pollutants graphene based bimorphs for micron sized autonomous origami machines physicists build muscle for shape changing cell sized robots behavioral evidence suggests facultative scavenging by a marine apex predator during a food pulse tiger sharks opt for scavenging on dead and dying sea turtles as a feeding strategy postdiagnosis social networks and breast cancer mortality in the after breast cancer pooling project women with more social connections have higher breast cancer survival study shows a hybrid type ia supernova with an early flash triggered by helium shell detonation violent helium reaction on white dwarf surface triggers supernova explosion high rates of species accumulation in animals with bioluminescent courtship displays evolutionary biologists show that sexual selection increases the number of species and impacts global diversity hydroxylamine as a potential indicator of nitrification in the open ocean tracing the process of nitrous oxide formation in the ocean yield stability analysis reveals sources of large scale nitrogen loss from the us midwest solving the mystery of fertilizer loss from midwest cropland the link a lncrna activates normoxic hif signalling in triple negative breast cancer study reveals potential therapy targets for triple negative breast cancer repeated and widespread evolution of bioluminescence in marine fishes new research shines light on surprising numbers evolutionary variety of bioluminescent ocean fish abrupt decline in tuberculosis among foreign born persons in the united states us tuberculosis cases drop almost percent among foreign born entrants from guidance on novel influenza a h n in solid organ transplant recipients swine flu has major implications for solid organ transplants transplant infectious disease experts provide pandemic guidance impact of bystander automated external defibrillator use on survival and functional outcomes in shockable observed public cardiac arrests cardiac arrest survival greatly increases when bystanders use an automated external defibrillator adult spinal cord radial glia display a unique progenitor phenotype new class of stem cell like cells discovered offers possibility for spinal cord repair archaeoteleia masner in the cretaceous and a new species of proteroscelio brues hymenoptera platygastroidea star dust wasp is a new extinct species named after david bowie s alter ego amphibian symbiotic bacteria do not show universal ability to inhibit growth of the global pandemic lineage ofbatrachochytrium dendrobatidis complex bacterial challenge in fight against deadly amphibian disease defining a good death successful dying literature review and a call for research and public dialogue successful dying researchers define the elements of a good death request a woman scientist a database for diversifying the public face of science a global database of women scientists is diversifying the face of science carbon focused conservation may fail to protect the most biodiverse tropical forests protecting tropical forest carbon stocks may not prevent large scale species loss adenosine amine congener mitigates noise induced cochlear injury new drug restores hearing after noise induced hearing loss in rats effects of caloric intake timing on insulin resistance and hyperandrogenism in lean women with polycystic ovary syndrome meal timing can significantly improve fertility in women with polycystic ovaries positive youth healthy adults does positive well being in adolescence predict better perceived health and fewer risky health behaviors in young adulthood ? positive teens become healthier adults adolescents with a sunny outlook on life may have better health in their adult years uk alcohol industry s billion units pledge interim evaluation flawed interim report on uk alcohol industry s billion units pledge is flawed say researchers distinct contribution of stem and progenitor cells to epidermal maintenance newly identified stem cell population in skin s epidermis responsible for tissue repair protective efficacy of the recombinant live attenuated cyd tetravalent dengue vaccine in thai schoolchildren a randomised controlled phase b trial results of dengue vaccine trial in over thai children experts respond a drosophila model for fetal alcohol syndrome disorders role for the insulin pathway figuring out fetal alcohol syndrome in fruit flies mercury exposure and antinuclear antibodies among females of reproductive age in the united states nhanes exposure to mercury seafood associated with risk factor for autoimmune disease transmission of extensively drug resistant tuberculosis in south africa study provides new evidence on role of person to person transmission in drug resistant tb rapid initialization of retrogressive thaw slumps in the canadian high arctic and their response to climate and terrain factors widespread permafrost degradation seen in high arctic terrain partially coherent radar unties range resolution from bandwidth limitations low bandwidth radar technology provides improved detection of objects disproportionate climate induced range loss forecast for the most threatened african antelopes climate change puts most threatened african antelopes in double jeopardy mailed intervention to promote sun protection of children trial shows effectiveness of low cost intervention to improve sun protection coffee consumption habits and the risk of mild cognitive impairment the italian longitudinal study on aging coffee consumption habits impact the risk of mild cognitive impairment a new genus of fleas with associated microorganisms in dominican amber previously unknown flea genus species discovered in fossilized dominican amber sperm counts may have declined in young university students in southern spain semen quality of young men in south east spain down by percent in the last decade edoxaban versus enoxaparin warfarin in patients undergoing cardioversion of atrial fibrillation ensure af a randomised open label phase b trial results of trial into anticoagulants for cardioversion in atrial fibrillation patients published the absence of vglut predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens understanding molecular mechanism leading to addiction in humans supplemental screening for breast cancer in women with dense breasts a systematic review for the u.s. preventive services task force more research needed on evaluation of dense breasts clinical genetic testing for patients with autism spectrum disorders better genetic test for autism ? chromosomal microarray analysis picks up more abnormalities than current tests decision making and trait impulsivity in bipolar disorder are associated with reduced prefrontal regulation of striatal reward valuation why people with bipolar disorder are bigger risk takers loss of heterozygosity at the cyp d locus in breast cancer implications for germline pharmacogenetic studies genotyping errors plague cyp d testing for tamoxifen therapy taxonomy morphology masticatory function and phylogeny of heterodontosaurid dinosaurs new fanged dwarf dinosaur from africa ate plants apol genetic variants in focal segmental glomerulosclerosis and hiv associated nephropathy gene variant increases risk of kidney disease in african americans relativistic deflection of background starlight measures the mass of a nearby white dwarf star century old relativity experiment used to measure a white dwarf s mass type iii interferons produced by human placental trophoblasts confer protection against zika virus infection trophoblasts resistant to zika zika in the mouse prevalence of cirrhosis in hepatitis c patients in the chronic hepatitis cohort study checs a retrospective and prospective observational study liver damage in hepatitis c patients significantly underestimated underreported genome wide association study identifies distinct genetic contributions to prognosis and susceptibility in crohn s disease crohn s disease risk and prognosis determined by different genes potential of systemic allogeneic mesenchymal stromal cell therapy for children with recessive dystrophic epidermolysis bullosa infusions of donor bone marrow cells help children with inherited skin blistering body size reduction in vertebrates following the end devonian mass extinction ancient mass extinction led to dominance of tiny fish paleontologist shows gene delivery to mitotic and postmitotic photoreceptors via compacted dna nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa toward making the blind see gene therapy restores vision in mice the escalating global burden of serious health related suffering projections to by world regions age groups and health conditions global burden of serious health related suffering due to almost double by alma observations of gas rich galaxies in z. galaxy clusters evidence for higher gas fractions in high density environments best measure of star forming material in galaxy clusters in early universe practice parameter treatment of nonmotor symptoms of parkinson disease report of the quality standards subcommittee of the american academy of neurology guideline issued for treating sleep constipation sexual problems in parkinson s disease therapeutic modulation of eif phosphorylation rescues tdp toxicity in amyotrophic lateral sclerosis disease models team reduces toxicity of lou gehrig s disease in animal models marine early triassic actinopterygii from elko county nevada usa implications for the smithian equatorial vertebrate eclipse large mouthed fish was top predator after mass extinction female reproductive disorders diseases costs of exposure to endocrine disrupting chemicals in the european union chemical exposure linked to. billion euros in women s health care costs study suggests scs macrophages suppress melanoma by restricting tumor derived vesicle b cell interactions macrophages surrounding lymph nodes block the progression of melanoma other cancers childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder ptsd research distinct gene activity patterns from childhood abuse partially native intermediates mediate misfolding of sod in single molecule folding trajectories protein associated with als points to possible targets for therapeutic intervention cleaner fuels for ships provide public health benefits with climate tradeoffs new fuel standards will decrease childhood asthma cases what s for dinner ? undescribed species of porcini in a commercial packet what s for dinner ? rapidly identifying undescribed species in a commercial fungi packet adult human mesenchymal stem cells msc delivered via intra articular injection to the knee following partial medial meniscectomy stem cell therapy following meniscus knee surgery may reduce pain restore meniscus trends in diagnoses of hiv infection in the united states rate of hiv diagnosis in u.s. examined in study risk of major adverse cardiovascular events and all cause mortality in patients with hidradenitis suppurativa hidradenitis suppurativa and risk of adverse cardiovascular events death nonsurgical management of urinary incontinence in women a clinical practice guideline from the american college of physicians new recommendations for treating urinary incontinence in women performance of new alternative providers of primary care services in england an observational study alternative providers of gp services perform worse than traditional practices prolonged california aridity linked to climate warming and pacific sea surface temperature pacific ocean s response to greenhouse gases could extend california drought for centuries sex differences in structural organization of motor systems and their dissociable links with repetitive restricted behaviors in children with autism girls boys with autism differ in behavior brain structure a cross sectional study of the association between ventilation of gas stoves and chronic respiratory illness in u.s. children enrolled in nhanesiii childhood asthma linked to lack of ventilation for gas stoves health risks in travelers to china the geosentinel experience and implications for the beijing olympics respiratory illnesses and dog bites a concern for travelers to china for olympics independent and combined effects of diethylhexyl phthalate and polychlorinated biphenyl on sperm quality in the human and dog chemical pollutants in the home degrade fertility in both men and dogs study finds re creating missing population baselines for pacific reef sharks scientists provide first large scale estimate of reef shark losses in the pacific ocean mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion scratching the skin primes the gut for allergic reactions to food mouse study suggests increased ionization supports growth of aerosols into cloud condensation nuclei the missing link between exploding stars clouds and climate on earth safety of very low low density lipoprotein cholesterol levels with alirocumab very low levels of bad cholesterol well tolerated in heart disease patients aristaless controls butterfly wing color variation used in mimicry and mate choice a single genetic switch changes butterfly wing color using and improving the social cost of carbon maintaining a reliable value of the cost of climate change changes in receipt of cancer screening in medicare beneficiaries following the affordable care act eliminating cost for colorectal cancer screening doesn t improve screening rates bisulfite free direct detection of methylcytosine and hydroxymethylcytosine at base resolution a new sequencing method to detect dna modifications of relevance to cancer exposure to fine airborne particulate matters induces hepatic fibrosis in murine models scientists discover mechanism for air pollution induced liver disease the relationship between sleep and cognitive function in patients with prediabetes and type diabetes poor sleep linked to lower cognitive functioning in people with diabetes and prediabetes reporting bias in clinical trials investigating the efficacy of second generation antidepressants in the treatment of anxiety disorders publication bias and spin raise questions about drugs for anxiety disorders synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic gabaareceptors on dendritic spines origin of synaptic pruning process linked to learning autism and schizophrenia identified trim suppresses cross species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species antiviral gene helps suppress jumping of aids viruses between host species changes in sensitivity of reward and motor behavior to dopaminergic glutamatergic and cholinergic drugs in a mouse model of fragile x syndrome child neurologist finds potential route to better treatments for fragile x autism lesions of the medial prefrontal cortex cause maladaptive sexual behavior in male rats frontal cortex dysfunction may contribute to compulsive sexual behavior study suggests an improved genome assembly uncovers prolific tandem repeats in atlantic cod stream of surprises from the atlantic cod genome mapping vaccination coverage to explore the effects of delivery mechanisms and inform vaccination strategies child vaccination levels falling short in large parts of africa preferences regarding return of genomic results to relatives of research participants including after participant death empirical results from a cancer biobank guidelines on sharing individual genomic research findings with family population genomic analysis of a pitviper reveals microevolutionary forces underlying venom chemistry toxic cocktail okinawan pit viper genome reveals evolution of snake venom tmk mediated auxin signalling regulates differential growth of the apical hook newly discovered mechanism of plant hormone auxin acts the opposite way preliminary recovery of coastal sharks in the south east united states preliminary recovery of coastal sharks in southeast us the missing light of the hubble ultra deep field making the hubble s deepest images even deeper orientation control of molecularly functionalized surfaces applied to the simultaneous alignment and sorting of carbon nanotubes mass production of new class of semiconductors closer to reality face specific memory deficits and changes in eye scanning patterns among patients with amnestic mild cognitive impairment preliminary stages of dementia reduce human face memorization ability molecular evolution in court analysis of a large hepatitis c virus outbreak from an evolving source evolutionary forensics used on hepatitis c virus outbreak minimum drinking age laws and infant health outcomes lower legal drinking age increases unplanned pregnancies and pre term births among young people weight gain in older adolescent females the internet sleep coffee and alcohol weight gain in adolescent girls role of internet alcohol and sleep evaluation of an organic nitrogen source in a yellow squash collard rotation hydrolyzed fish fertilizer tested in organic vegetable production pacific decadal and el ni o oscillations shape survival of a seabird the survival of sea birds affected by ocean cycles industry use of evidence to influence alcohol policy a case study of submissions to the scottish government consultation study reveals alcohol industry tactics to influence alcohol policy reform in scotland paid family leave s effect on hospital admissions for pediatric abusive head trauma paid family leave linked to fewer kids hospital admissions for abusive head injury remembering one s identity the epigenetic basis of stem cell fate decisions adult stem cells carry their own baggage epigenetics guides stem cell fate automated pose estimation captures key aspects of general movements at weeks from conventional videos artificial intelligence identifies key patterns from video footage of infant movements in vivo delivery of fty prevents radiation induced ovarian failure and infertility in adult female nonhuman primates protective strategy shields primate ovaries from radiation therapy induced damage suppression of autophagic activity by rubicon is a signature of aging the key to increased lifespan ? rubicon alters autophagy in animals during aging social ecological correlates of polyvictimization among a national sample of transgender genderqueer and cisgender sexual minority adolescents transgender and gender fluid teens left with few safe harbors association between unconventional natural gas development in the marcellus shale and asthma exacerbations fracking industry wells associated with increased risk of asthma attacks the gulf of carpentaria heated torres strait and the northern great barrier reef during the mass coral bleaching event perfect storm led to great barrier reef bleaching vitamin d and aromatase inhibitor induced musculoskeletal symptoms aimss a phase ii double blind placebo controlled randomized trial vitamin d relieves joint muscle pain for breast cancer patients brain basis of cognitive resilience prefrontal cortex predicts better reading comprehension in relation to decoding link found between resilience to dyslexia and gray matter in the frontal brain a distance weighted interaction map reveals a previously uncharacterized layer of the bacillus subtilis spore coat biologists discover an extra layer of protection for bacterial spores neubtracker imaging neurobehavioral dynamics in freely behaving fish tracking live brain activity with the new neubtracker open source microscope antisense oligonucleotide mediated mdm exon skipping impairs tumor growth research reveals promising novel strategy to target cancer causing protein the influence of religion on science the case of the idea of predestination in biospeleology influence of religion and predestination on evolution and scientific thinking new species of microhyla from sarawak old world s smallest frogs crawl out of miniature pitcher plants on borneo amphibia anura microhylidae tiny new pea sized frog is old world s smallest relationship between alcohol use categories and noninvasive markers of advanced hepatic fibrosis in hiv infected chronic hepatitis c virus infected and uninfected patients drinking even casual amounts poses much greater risk for advanced liver disease in hiv hepatitis c patients hybrid songbirds employ intermediate routes in a migratory divide mixed genes mix up the migrations of hybrid birds high throughput classification of clinical populations from natural viewing eye movements studying everyday eye movements could aid in diagnosis of neurological disorders improving heart health among black african american women using civic engagement a pilot study could community based change clubs improve heart health in black women ? management of patients with multidrug resistant extensively drug resistant tuberculosis in europe a tbnet consensus statement tackling multidrug resistant extensively drug resistant tb new consensus reached the path to routine genomic screening in health care routine genomic screening could find risks for cancer and heart disease in to million inhibition of prc activity by a gain of function h mutation found in pediatric glioblastoma mechanism of mutant histone protein in childhood brain cancer revealed new constraints on radii and tidal deformabilities of neutron stars from gw physicists set limits on size of neutron stars expanding the happiness paradox ethnoracial disparities in life satisfaction among older immigrants in the united states older immigrants living in us more satisfied with life than native born counterparts brain imaging tests for chronic pain medical legal and ethical issues and recommendations new guidelines discourage use of brain imaging as a lie detector for chronic pain over reassurance and undersupport after a false alarm a systematic review of the impact on subsequent cancer symptom attribution and help seeking a cancer false alarm could discourage people from checking out future symptoms hdac inhibitors enhance neratinib activity and when combined enhance the actions of an anti pd immunomodulatory antibody in vivo new breast cancer drug defeats the ras genes notorious for causing many types of cancer musical experience and neural efficiency effects of training on subcortical processing of vocal expressions of emotion musicians have biological advantage in identifying emotion in sound classifying degraded modern polymeric museum artefacts by their smell the degradation status of modern polymeric museum artifacts can be classified by their smell increased calcium influx through l type calcium channels in human and mouse neural progenitors lacking fragile x mental retardation protein genetic background of autistic spectrum disorders with stem cell dysfunction pre clovis projectile points at the debra l. friedkin site texas implications for the late pleistocene peopling of the americas oldest weapons ever discovered in north america pre date clovis trends in animal use at us research facilities sharp rise in experimental animal research in us later school start time is associated with improved sleep and daytime functioning in adolescents later school start times improve sleep and daytime functioning in adolescents can community and school based supports improve the achievement of first generation immigrant children attending high poverty schools ? connecting disadvantaged immigrant students to community resources may boost school achievement reprogramming metabolism by targeting sirtuin attenuates retinal degeneration retinitis pigmentosa may be treated by reprogramming sugar metabolism efficient and allele specific genome editing of disease loci in human ipscs crispr science newer genome editing tool shows promise in engineering human stem cells regulation of inflammatory responses by gut microbiota and chemoattractant receptor gpr diet and intestinal bacteria linked to healthier immune systems safety and immunogenicity of ebola virus and marburg virus glycoprotein dna vaccines assessed separately and concomitantly in healthy ugandan adults a phase b randomised double blind placebo controlled clinical trial trial confirms ebola vaccine candidate safe equally immunogenic in africa differing symptom patterns in early pandemic vs seasonal influenza infections symptom patterns differ between pandemic seasonal flu in singapore spatiotemporal multi omics mapping generates a molecular atlas of the aortic valve and reveals networks driving disease a molecular atlas of calcific aortic valve disease diet switching of seed eating birds wintering in grazed habitats of the central monte desert argentina some birds better than others at adjusting to habitat degradation gastrointestinal neuroimmune disruption in a mouse model of gulf war illness gi neuroimmune disruption contributes to gulf war illness model of colonic inflammation immune modulatory mechanisms in inflammatory bowel disease math model of colon inflammation singles out dangerous immune cells using active choice within the electronic health record to increase influenza vaccination rates a little nudge may provide a big boost to flu vaccination rates bisnorgammacerane traces predatory pressure and the persistent rise of algal ecosystems after snowball earth how predatory plankton created modern ecosystems after snowball earth physical activity is positively associated with episodic memory in aging physical activity linked to better memory among older adults parkin elimination of mitochondria is important for maintenance of lens epithelial cell ros levels and survival upon oxidative stress exposure study first to demonstrate role of parkin gene in eye lens free radical formation and cell survival transient exciton polariton dynamics in wse by ultrafast near field imaging new technology captures movement of quantum particles with unprecedented resolution hiv broadly neutralizing antibody precursor b cells revealed by germline targeting immunogen new findings in humans provide encouraging foundation for upcoming aids vaccine clinical trial tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis new d imaging technique reveals how pancreatic cancers start a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction reduce lap hf i a phase randomized sham controlled trial first transcatheter implant for diastolic heart failure successful a simple genetic architecture underlies morphological variation in dogs dogs physical traits controlled by small number of genetic regions researcher finds deep reefs of the great barrier reef offer limited thermal refuge during mass coral bleaching coral bleaching on great barrier reef not limited to shallow depths single nucleus hi c reveals unique chromatin reorganization at oocyte to zygote transition unique genome architectures after fertilization in single cell embryos new and recurrent concussions in high school athletes before and after traumatic brain injury laws tbi laws effective at reducing rate of recurrent concussions new study shows efficacy of bleach baths in reducing severity of atopic dermatitis a systematic review and meta analysis water baths as good as bleach baths for treating eczema discovery of a diverse cave flora in china new research reveals plant wonderland inside china s caves watershed scale impacts from surface water disposal of oil and gas wastewater in western pennsylvania release of treated wastewater from hydraulic fracturing contaminates lake olig and hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics gene network that regulates motor neuron formation during embryonic development compromised blood brain barrier competence in remote brain areas in ischemic stroke rats at chronic stage blood brain barrier repair after stroke may prevent chronic brain deficits common variants in psychiatric risk genes predict brain structure at birth risk genes for alzheimer s and mental illness linked to brain changes at birth effects of natural disasters on conservation policies the case of the wenchuan earthquake china quakes don t completely shake china s environmental gains thanks to conservation programs positive and negative experiences of social support and risk of dementia in later life an investigation using the english longitudinal study of ageing better quality relationships associated with reduced dementia risk role of the trochlear nerve in eye abduction and frontal vision of the red eared slider turtle trachemys scripta elegans turtle eye muscle adapts to deal with obstructed vision sequencing of the sea lamprey petromyzon marinus genome provides insights into vertebrate evolution scientists find genes linked to human neurological disorders in sea lamprey genome joint attention initiation with and without positive affect risk group differences and associations with asd symptoms early warning sign for babies at risk of autism early joint attention predicts later autism symptoms subclinical atherosclerosis measures for cardiovascular prediction in ckd coronary calcium predicts heart disease risk in patients with chronic kidney disease dynamic self cleaning in gecko setae via digital hyperextension scientists gain understanding of self cleaning gecko foot hair higher sequence diversity in the vaginal tract than in blood at early hiv infection hiv genetic diversity is higher in vaginal tract than in blood during early infection phase trials of rvsv ebola vaccine in africa and europe preliminary report experts test new ebola vaccine on front line medical personnel and at risk groups after promising results moving towards better cause of death registration in africa and asia largest ever dataset of individual deaths in africa se asia reveals changing health referral to an extracorporeal membrane oxygenation center and mortality among patients with severe influenza a h n treatment with oxygenating system associated with lower risk of death for h n patients with respiratory failure the oltulelei formation of the southern kenyan rift valley a chronicle of rapid landscape transformation over the last k.y. new understanding of kenyan paleoenvironments opens window on human evolution in the area health of common bottlenose dolphins tursiops truncatus in barataria bay louisiana following thedeepwater horizonoil spill deepwater horizon study shows possible oil impact on dolphins communication between asian american adolescents and health care providers about sexual activity sexually transmitted infections and pregnancy prevention sexual health communication between asian american adolescents and health care providers intravital imaging by simultaneous label free autofluorescence multiharmonic microscopy new tissue imaging technology could enable real time diagnostics map cancer progression improvement in patient reported visual function after ocriplasmin for vitreomacular adhesion vitreomacular adhesion patients report improved vision with non surgical treatment the axolotl genome and the evolution of key tissue formation regulators decoding the axolotl genome insights into tissue regeneration effect of teenage motherhood on cognitive outcomes in children a population based cohort study children born to teen mothers have delayed development likely due to social factors vulnerability to the mortality effects of warm temperature in the districts of england and wales southeast england most at risk of rising deaths due to climate change genetic ancestry influences asthma susceptibility and lung function among latinos asthma risk varies with ethnic ancestry among latinos reproductive conflict and the evolution of menopause in killer whales why do killer whales go through menopause ? mother daughter conflict is key electronic origin of hydrogen storage in mof covered palladium nanocubes investigated by synchrotron x rays interfacial electronic state improving hydrogen storage capacity in pd mof materials multivariate computational analysis of gamma delta t cell inhibitory receptor signatures reveals the divergence of healthy and art suppressed hiv aging unique immune cell likely drives chronic inflammation researchers discover head impact exposure in youth football comparing age and weight based levels of play head impact exposure increases as youth football players get older bigger analysis of the androgen receptor regulated lncrna landscape identifies a role for arlnc in prostate cancer progression genome s dark matter offers clues to major challenge in prostate cancer movements and oceanographic associations of bigeye tuna thunnus obesus in the northwest atlantic study of bigeye tuna in northwest atlantic uses new tracking methods nanoparticle solutions as adhesives for gels and biological tissues revolutionary method for gluing gels and biological tissues principal component regression of academic performance substance use and sleep quality in relation to risk of anxiety and depression in young adults how college students can end up in vicious cycle of substance abuse poor academics stress magnetic axis drift and magnetic spot formation in neutron stars with toroidal fields magnetic hot spots on neutron stars survive for millions of years exercise induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism exercise induced hormone irisin linked to new mechanisms for bone metabolism differences in breast feeding initiation and continuation by maternal diabetes status breastfeeding initiation success impacted by diabetes status of mother immune evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury gene therapy restores hand function after spinal cord injury in rats claims for fertility interventions a systematic assessment of statements on uk fertility centre websites lack of supporting evidence for claims about fertility treatments a nutrient dense high fiber fruit based supplement bar increases hdl particularly large hdl lowers homocysteine and raises glutathione in in a week trial new nutrition bar improves metabolic biomarkers linked to cardiovascular disease cognitive decline and anti oxidant defenses in only two weeks oc what triggers osteoporosis therapy in high risk residents living in long term care ltc homes ? the gaining optimal osteoporosis assessments in long term care goal study hip fracture patients in long term care are less likely to receive osteoporosis therapy volcanic dust veils from sixth century tree ring isotopes linked to reduced irradiance primary production and human health unusual climate during roman times plunged eurasia into hunger and disease phase study of temozolomide based chemoradiation therapy for high risk low grade gliomas preliminary results of radiation therapy oncology group combination therapy best for low grade brain tumors clinical trial suggests similar spatial patterns of climate responses to aerosol and greenhouse gas changes increased greenhouse gases and aerosols have similar effects on rainfall association of social determinants with children s hospitals preventable readmissions performance readmission rates at children s hospitals influenced by patients characteristics long term effectiveness of dopamine agonists and monoamine oxidase b inhibitors compared with levodopa as initial treatment for parkinson s disease pd med a large open label pragmatic randomised trial levodopa better than newer drugs for long term treatment of parkinson s largest ever trial shows altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans patients with paraplegia regain voluntary movement after spinal stimulation is it time for brca mutation screening in the general adult population ? impact of population characteristics pathology specialist contributes to debate on breast cancer gene screening evidence of newell s shearwaters and hawaiian petrels on oahu hawaii possible oahu populations offer new hope for hawaiian seabirds transplantation of mouse hscs genetically modified to express a cd restricted tcr results in long term immunity that destroys tumors and initiates spontaneous autoimmunity gene therapy for metastatic melanoma in mice produces complete remission lifestyle and metabolic syndrome in adult survivors of childhood cancer a report from the st. jude lifetime cohort study lifestyle choices may affect long term heart health of childhood cancer survivors lab in a box semi automatic tracking of activity in the medical office lab in a box takes aim at doctors computer activity non invasive prenatal testing for aneuploidy and beyond challenges of responsible innovation in prenatal screening position statement on non invasive prenatal screening issued an apparatus for studying electrical breakdown in liquid helium at. k and testing electrode materials for the neutron electric dipole moment experiment at the spallation neutron source demonstrating strong electric fields in liquid helium for tests of matter antimatter symmetry measurement of the cosmic optical background using the long range reconnaissance imager on new horizons scientist measures brightness of the universe with nasa s new horizons spacecraft hydrogen bubble propelled zinc based microrockets in strongly acidic media bubble powered microrockets zoom have potential to zoom through the human stomach other acidic environments downsizing policy options to reduce portion sizes to help tackle obesity reducing food portion sizes critical to tackle obesity argue experts photoresponsive liquid crystalline epoxy networks with shape memory behavior and dynamic ester bonds shape changing smart material heat light stimulate self assembly growth rings of brazil nut trees bertholletia excelsa as a living record of historical human disturbance in central amazonia human history through tree rings trees in amazonia reveal pre colonial human disturbance human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells joint cartilage development tracked in humans for first time web based parent training intervention with telephone coaching for disruptive behavior in year old children in real world practice implementation study digital parent training for child s disruptive behavior successful in primary health care intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury stem cell treatment mediates immune response to spinal cord injury in pre clinical trials epigenomic enhancer profiling defines a signature of colon cancer breakthrough discovery unveils master switches in colon cancer regional level correlations in inappropriate imaging rates for prostate and breast cancerspotential implications for the choosing wisely campaign geography matters imaging overuse seen for breast prostate cancer in certain regions across the u.s. re opening the critical window for estrogen therapy gene therapy used to extend estrogen s protective effects on memory growth of human breast tissues from patient cells in d hydrogel scaffolds engineered hydrogel scaffolds enable growth of functioning human breast tissue patterns and functional implications of rare germline variants across cancer types study uncovers inherited genetic susceptibility across cancer types trigger point evaluation in migraine patients an indication of peripheral sensitization linked to migraine predisposition ? botox injected in head trigger point shown to reduce migraine crises prenatal micronutrient supplementation and intellectual and motor function in early school aged children in nepal prenatal micronutrient supplementation boosts children s cognition in nepal benefits harms and cost effectiveness of supplemental ultrasonography screening for women with dense breasts women with dense breasts will have to look beyond ultrasound for useful supplemental breast cancer screening human esc derived mscs outperform bone marrow mscs in the treatment of an eae model of multiple sclerosis embryonic stem cells offer new treatment for multiple sclerosis trends in caregiving assistance for home dwelling functionally impaired older adults in the united states study shows a rising but uneven tide of in home care for disabled seniors race and colorectal cancer disparities healthcare utilization versus different cancer susceptibilities new study implicates health care utilization over biology in colorectal cancer disparities prevalence of allergic disease in foreign born american children u.s. children born outside the united states have lower risk of allergic disease experimental realization of wave packet dynamics in cyclic quantum walks in the blink of an eye team uses quantum of light to create new quantum simulator state disparities in colorectal cancer rates contributions of risk factors screening and survival differences applying new jersey population traits to louisiana reverses colorectal cancer trends e f regulatory program predicts patient survival prognosis in breast cancer prognostic test developed for e f in breast cancer countries with higher levels of gender equality show larger national sex differences in mathematics anxiety and relatively lower parental mathematics valuation for girls girls more anxious about mathematics stem subjects compared to boys combining realism with control impact of controlled neonicotinoid exposure on bumblebees in a realistic field setting impact of pesticide on bumblebees revealed by taking experiments into the field tongue coating microbiome data distinguish patients with pancreatic head cancer from healthy controls tongue microbiome could help identify patients with early stage pancreatic cancer statin use is associated with prolonged patient and graft survival in renal transplant recipients statins linked to improved survival in kidney transplant recipients global use of peripheral blood vs bone marrow as source of stem cells for allogeneic transplantation in patients with bone marrow failure source of stem cells used for bone marrow failure treatment varies worldwide what the beep ? six month olds link novel communicative signals to meaning what the beep ? infants link new communicative signals to meaning a manganese hydride molecular sieve for practical hydrogen storage under ambient conditions new material could unlock potential for hydrogen powered vehicle revolution lameness scoring and assessment of fitness for transport in dairy cows agreement among and between farmers veterinarians and livestock drivers evaluation of fitness for transport of cull cows varies association between serum vitamin d levels and cardiorespiratory fitness in the adult population of the usa vitamin d levels in the blood linked to cardiorespiratory fitness potential role of adolescent alcohol exposure induced amygdaloid histone modifications in anxiety and alcohol intake during adulthood adolescent drinking affects adult behavior through long lasting changes in genes is tv traumatic for all youths ? the role of preexisting posttraumatic stress symptoms in the link between disaster coverage and stress children s preexisting symptoms influence their reactions to disaster coverage on tv drivers of inequality in millennium development goal progress a statistical analysis hiv and noncommunicable diseases hinder the progress of poor countries millennium development goals response of consumer and research grade indoor air quality monitors to residential sources of fine particles mixed report card for low cost indoor air quality home monitors expression of hla class i antigen aspirin use and survival after a diagnosis of colon cancer aspirin use appears linked with improved survival after colon cancer diagnosis emergence of a stage dependent human liver disease signature with directed differentiation of alpha antitrypsin deficient ips cells ipsc model helps to better understand genetic lung liver disease the effects of sub regional climate velocity on the distribution and spatial extent of marine species assemblages species groups follow patterns reacting to climate change on us northeast shelf imaging large scale cellular activity in spinal cord of freely behaving mice tiny microscopes reveal hidden role of nervous system cells deceptive signals and behaviors of a cleptoparasitic beetle show local adaptation to different host bee species beetle adapts chemical mimicry to parasitize different bee species reduced accumulation of defective viral genomes contributes to severe outcome in influenza virus infected patients newly discovered viral marker could help predict flu severity in infected patients hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche live imaging captures how blood stem cells take root in the body source forensics of black carbon aerosols from china researchers constrain the sources of climate and health afflicting air pollution from china cognitive resource allocation determines the organisation of personal networks a scientific study characterizes our circles of friendships t cell activation is an immune correlate of risk in bcg vaccinated infants biomarker discovery offers hope for new tb vaccine dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder suicide risk variety of dialectical behavior therapy interventions with therapists effective drug facilitated sexual assault college women s risk perception and behavioral choices researcher calls for increase in sexual assault awareness programs on college campuses injury intense dust exposure and chronic disease among survivors of the world trade center terrorist attacks of september survivors may be at increased risk of heart and lung disease years later targeting breast cancer initiating stem cells with melanoma differentiation associated gene interleukin mda il targeted viral therapy destroys breast cancer stem cells in preclinical experiments evidence for a stromal epithelial lactate shuttle in human tumors mct is a marker of oxidative stress in cancer associated fibroblasts simple sugar lactate is like candy for cancer cells cancer cells accelerate aging and inflammation in the body to drive tumor growth diet and risk of diverticular disease in oxford cohort of european prospective investigation into cancer and nutrition epic prospective study of british vegetarians and non vegetarians vegetarian diet may protect against common bowel disorder short course radiation plus temozolomide in elderly patients with glioblastoma glioblastoma clinical trial shows combined therapy extends life for patients and older spatial charge inhomogeneity and defect states in topological dirac semimetal thin films of na bi electronically smooth d graphene a bright future for trisodium bismuthide in vivo and in silico dynamics of the development of metabolic syndrome new computational tool predicts progression of metabolic syndrome in mice holocene indian ocean tsunami history in sri lanka new study reconstructs mega earthquakes timeline in indian ocean maternal inflammation contributes to brain overgrowth and autism associated behaviors through altered redox signaling in stem and progenitor cells neural stem cell overgrowth autism like behavior linked mice study suggests joint attention without gaze following human infants and their parents coordinate visual attention to objects through eye hand coordination cognitive scientists id mechanism central to early childhood learning social behavior prevalence of gambling problems among the clients of a toronto homeless shelter gambling history is common among homeless people in toronto new study combined impact of smoking and heavy alcohol use on cognitive decline in early old age whitehall ii prospective cohort study combination of smoking and heavy drinking speeds up cognitive decline bedmachine v complete bed topography and ocean bathymetry mapping of greenland from multibeam echo sounding combined with mass conservation new greenland maps show more glaciers at risk infliximab azathioprine or combination therapy for crohn s disease two drug combo twice as effective for crohn s disease remission study suggests implications of floral orientation for flight kinematics and metabolic expenditure of hover feeding hummingbirds high speed video and artificial flowers shed light on mysteries of hummingbird pollinated flowers the gist of the abnormal above chance medical decision making in the blink of an eye medical assessment in the blink of an eye impact of nutrition on muscle mass strength and performance in older adults which nutritional factors help preserve muscle mass strength and performance in seniors ? a hypothetical effect of the maxwell proca electromagnetic stresses on galaxy rotation curves physicists analyze rotational dynamics of galaxies and influence of the photon mass effect of cannabidiol on drop seizures in the lennox gastaut syndrome cannabidiol significantly reduces seizures in patients with severe form of epilepsy full scale shaking table tests on a substandard rc building repaired and strengthened with post tensioned metal straps building belt offers cheap quick repair of earthquake damage a discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer groundbreaking discovery of the cellular origin of cervical cancer re expression of tumor suppressor sfrp leads to antitumor synergy of combined hdac and methyltransferase inhibitors in chemoresistant cancers. drug duo turns on cancer fighting gene in kidney breast cancers differences in the metabolic rates of exploited and unexploited fish populations a signature of recreational fisheries induced evolution ? differences in metabolic rates of exploited unexploited fish populations new class of selective estrogen receptor degraders serds expanding the toolbox of protac degrons a novel molecule could spur new class of drugs for breast cancer oocyte formation by mitotically active germ cells purified from ovaries of reproductive age women egg producing stem cells isolated from adult human ovaries association between folate levels and cpg island hypermethylation in normal colorectal mucosa high red blood cell folate levels linked to silenced tumor suppressors multimessenger observations of a flaring blazar coincident with high energy neutrino icecube a breakthrough in the search for cosmic particle accelerators comparative efficacy of psychological therapies for improving mental health and daily functioning in irritable bowel syndrome a systematic review and meta analysis type of psychotherapy matters in treatment of irritable bowel syndrome