bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nerinetide Reduces Early Infarct Growth Among Stroke Patients Undergoing EVT Without Intravenous Alteplase
Authors: Rex Nathaniel B. , Ospel Johanna M. , McDonough Rosalie V. , Kashani Nima , Rinkel Leon A. , Buck Brian H. , Rempel Jeremy , McTaggart Ryan A. , Nogueira Raul G. , Poppe Alexandre Y. , Dowlatshahi Dar , van Adel Brian A. , Swartz Richard H. , Shah Ruchir A. , Sauvageau Eric , Demchuk Andrew M. , Tymianski Michael , Hill Michael D. , Goyal Mayank ,   the ESCAPE‐NA1 Investigators
Published: February 2024

Background
Nerinetide treatment was associated with better clinical outcomes among patients with stroke undergoing endovascular treatment who were not treated with concurrent alteplase in the randomized ESCAPE‐NA1 (Efficacy and Safety of Nerinetide for the Treatment of Acute Ischemic Stroke) trial. In patients receiving alteplase, no such effect was seen due to an inactivation of nerinetide by plasmin – the product of tissue plasminogen activation. We hypothesized that improved outcomes in the no‐alteplase patients were associated with reduced infarct growth, a radiological correlate of improved stroke outcomes.

Methods
Data are from the no‐alteplase stratum of the ESCAPE‐NA1 trial. Patients who underwent computer tomography perfusion (CTP) as part of routine clinical care were included. Admission CTP source data were processed using RAPID software. Infarct core at baseline was defined as areas of relative cerebral blood flow <30% on CTP. Final infarct volume was determined via manual segmentation on 24‐hour CT or magnetic resonance diffusion‐weighted imaging. We compared infarct growth (defined as 24‐hour infarct volume minus CTP‐estimated baseline infarct core) among no‐alteplase patients treated with versus without nerinetide.

Results

CTP maps were available in 413/1105 (37%) ESCAPE‐NA1 participants. Of these, 179 (43%) were treated without alteplase, 79 (44%) received nerinetide, and 100 (56%) received placebo. Prior administration of alteplase modified the treatment effect of nerinetide on infarct growth in a multivariable model that was adjusted for age, sex, baseline infarct core volume, expanded Thrombolysis in Cerebral Infarction score, and time from baseline imaging to reperfusion (
P
= 0.005). In no‐alteplase patients, infarct growth was larger over 24 hours in the control (34.9 mL interquartile range[IQR] [6.8–127]) versus nerinetide (19.6 mL IQR [1.7–49.1];
P
= 0.008) groups. In patients who received prior alteplase (n = 234), there was no difference in infarct growth between those who received placebo versus nerinetide (10.5 mL IQR [−1.3 to 67.4] versus 12.8 mL IQR [0.35–55.5];
P
= 0.62).

Conclusion
Nerinetide was associated with decreased infarct growth in acute ischemic stroke patients undergoing thrombectomy without concurrent alteplase in the ESCAPE‐NA1 trial.
From the Triple Helix Model of Innovations to the Quantitative Theory of Meaning
Authors: Ivanova Inga 
Published: February 2024

Abstract
The paper dates back to the period when the author became acquainted with Loet Leydesdorff and is mainly devoted to the research that the author had the opportunity to conduct together with Loet. Major research topics include the development of the Triple Helix model and the dynamic model of inter-social communication, which appear to be closely interrelated. The full consequences of his work are yet to be realized. I also present a vision of possible applications and future extensions of Loet’s work.
The Church Registration Processes in the Czech Republic: Current Situation from the Perspective of Sociological Jurisprudence
Authors: Rigel Filip , Tlčimuková Petra 
Published: February 2024

Abstract
The study presents a critical view of the church registration processes in the Czech Republic from a sociological jurisprudence perspective. First, it reviews the main issues as they appear in the current debate on the relationship between the state and religion. Next, it addresses the socio-cultural specifics of the relationship between state and religion in the Czech Republic and describes the current legal settings. The analytical part focuses on the judicial review of church registration processes between 2010 and 2022. Finally, the authors review individual cases and their legal outcomes to gain insight into the key problematic issues. The authors argue that (a) the national legal setting creates an unequal environment for the organizations that have been assessed in the study, and that (b) consequently, the state often exceeds its authority in the church registration process.
The Black Stone and the City of Light: Devotional Cityscapes and the Poetics of “Idolatry” in Matan Lāl Āfarīn Persian Mas̱nawī on Vārāṇasī (1778–9)
Authors: Pellò Stefano 
Published: February 2024

Abstract
This paper explores a hitherto unstudied Persian masnawī in praise of the sacred city of Vāraṇāsī, the Kāšī-stut (a phonetically Persianized variant of kāśī stuti, “Hymn to Vārāṇasī”) composed in 1778–9 by a little known Kāyastha scribe from Allahabad, Matan Lāl Āfarīn. The text, is an original poetic transposition of the Hindu religious landscape of Vārāṇasī in Persian verse, conjuring classical and post-classical Persian poetic conventions on the non-Islamic sphere and Sanskrit models such as the Kāśīkhaṇḍa, the Kāśīrahasya or other māhātmyas, and containing an impressive amount of descriptions (sometimes very technical) of idols, temples, pilgrimages, devotees, ascetics, the Ganges and so on. In view of the extraordinary value of the document (from the historical as well as from the literary side) the main aim of the article is not only to discuss the complex socio-cultural entanglements of the treatment of “idolatry” by a late eighteenth-century Hindu poet of Persian, but also, at the same time, to present, as far as I know for the first time, an important Persian document on early modern Vārāṇasī hitherto completely ignored by scholars. The study of the text against the background of contemporary trends in Persian poetry, in South Asia as well as in Iran, will, moreover, provide us with a proper set of interpretative tools for reading what we should begin to call the Hindu Persian literature of the eighteenth century.
David’s Descendants: Legitimacy and Identity Representations of the Converted Safavid Viceroys in East Georgia (1580–1724)
Authors: Kharebava Nana 
Published: February 2024

Abstract
This scholarly exploration delves into the intersection of religious alignment and the validity of governance within identity representations embodied by the Safavid Viceroys (1501–1722), the Georgian Kings of Kartli and Kakheti. Nestled between the Greater and Lesser Caucasus, these eastern Georgian territories stood not merely as the focal point of Safavid Iran’s political aspirations but also attracted the attention of Ottoman and Russian imperial strategies. The bi-centennial discord involving Georgian monarchs and their Muslim liege lords transcended conventional political and martial realms, seeping into the spheres of cultural and religious discourse. Within this context, the religious affinities of Georgian subordinates crystallised into a pivotal aspect of the Safavid-Georgian interactions, precipitating the evolution of divergent, fabricated religious affiliations. The Georgian-Persian bilingual documents furnish an invaluable comparative lens to juxtapose the variant religious portrayals of a single Georgian King, in his role as a Safavid Viceroy.
White Supremacy and the January 6 Insurrection
Authors: DiMaggio Anthony , Wahlrab Amentahru , Ochs Holona 
Published: February 2024

Abstract
In this paper, we argue that white supremacist values have been mainstreamed in the United States, and that the values driving the male supremacist and white supremacist movements are significant in fueling mass sympathy for January 6th (J6). To examine the white and male supremacy questions in relation to J6, we draw on a national survey from IPSOS. We also commissioned a poll with Harris Insights. The IPSOS poll was conducted from July 30 to August 16, 2021, and includes a nationally representative sample of 5,299 Americans. The Harris poll was conducted from October 20–25, 2022, and contacted a nationally representative sample of 2,029 Americans. We argue that J6 should be understood at the nexus point between white supremacist, populist, and fascist politics, not only in terms of the values driving the insurrectionists, but those in the mass public who are sympathetic to them. Right-wing populism, we believe, privileges white supremacy and white nationalism, male supremacy and political leadership that relies on an appeal to the cult of patriarchal personality, trust in the wisdom of “the people,” and distrust of political leaders – particularly Democratic leaders – who are framed as “corrupt,” “out of touch” “elites” working against the public good and democracy.
Three Provocations concerning the Uses of Populism
Authors: Arditi Benjamin 
Published: February 2024

Abstract
This article outlines three provocations to shake up the comfort zone of populism studies. These are: that populism may have become an anachronism and we should think about moving on; that populism may work better as a term of derision, as democracy was for the ancient Greeks; that we should describe it as a historical phenomenon, something that happened in the mid-twentieth century but is no longer current. So, my suggestion to populism scholars is to drop the term, use it to disqualify opponents, or refer to it as something that happened some time ago.
Populism without a People, or the Politics of Proximity
Authors: Annunziata Rocío 
Published: February 2024

Abstract
There is a tendency to find populist characteristics in all experiences of representation based on personal leaderships which present themselves as outsiders and establish direct communication with the citizenry. This paper seeks to contribute to avoid this conceptual stretching, proposing to start from a concept of a higher level of generality, “immediate politics”, and then differentiate between a populist type and a type that I will call “proximity”. The anti-charismatic or proximity identification is based on the figure of the “ordinary person”, close and empathetic, although without the component of “extraordinary person” implied in charisma, and without the correlate of the construction of a collective subject or People. In short, this paper asks about this kind of “populism without a People” that is also present in contemporary politics.
Populist Inclusion of Ecuadorian Emigrants under Rafael Correa’s Presidency
Authors: Selçuk Orçun , Valdivieso Salomé 
Published: February 2024

Abstract
This article studies Rafael Correa’s populist inclusion of Ecuadorian emigrants. It unpacks Correa’s inclusionary populism toward the emigrants at symbolic, political, and material levels. The article utilizes a qualitative content analysis of Correa’s weekly TV show, the Citizen Link (2007–2017). The findings reveal that Correa considered the emigrants as part of “the people,” who were forced to leave the country after the 1999 Banking Crisis. In line with his left-wing populist leadership, Correa viewed them as the victims of neoliberalism and the financial elite. Moreover, Correa politically included the emigrants by extending their voting rights and creating permanent seats in the National Assembly. Finally, Correa materially included the Ecuadorian emigrants by increasing the number of embassies, consulates, and cultural houses as well as facilitating the emigrants’ return. These findings have implications for the relationship between populism and emigration in Latin America and other migrant-sending regions.
Course and Outcome of Anorexia Nervosa in Adolescents from a Tertiary-level Mental Health Setting in India: A Retrospective Chart Review
Authors: Sravanti Lakshmi , Velusamy Arul , Karki Utkarsh , Kommu John Vijay Sagar , Girimaji Satish Chandra 
Published: February 2024

Background: Anorexia nervosa is one of the least studied mental health conditions in the Indian setting. The objective of this study was to assess the course and outcome of anorexia nervosa in adolescents who had presented to a tertiary care child and adolescent psychiatry center over a period of 10 years. Methods: The present study is a retrospective chart review of adolescents (up to the age of 18 years) with a diagnosis of anorexia nervosa, coded as F50.0 or F50.1 according to ICD 10, from 1st April 2009 to 31st March 2019. Data were extracted from the case records using standardized abstraction forms and evaluated using descriptive and nonparametric statistics. Results: The average age at presentation and the average age at onset were 14.1 years and 13.1 years, respectively. The male-to-female ratio of the sample who got admitted was 1:9. The average duration of hospital stay was about 30 days. The duration of in-patient care and weight gain were positively correlated, with severe to extremely ill adolescents improving even in less than one month of in-patient care. Seventy per cent of the admitted adolescents followed up. The functional outcome as measured by a ‘return to school’ improved in 57.1% of the sample. Conclusions: The present study highlights the collaborative multidisciplinary and individualized treatment approach employed for adolescents diagnosed with anorexia nervosa within an inpatient mental health facility in India. Adolescents who presented with more severe illness at the initial assessment, such as an early onset of symptoms and a low BMI, experienced substantial weight gain that exhibited a positive correlation with the length of their stay in the inpatient facility.
A Bibliometric Analysis of Scientific Publications on Customer Loyalty in the Insurance Industry
Authors: Singla Sherry , Sawhney Harpreet Kaur 
Published: February 2024

This bibliometric analysis makes a deliberate attempt to convey quantitative and qualitative knowledge on loyalty with regard to the insurance industry. The study includes an examination of 132 articles that were published between 2002 and 2022. he research articles were subjected to bibliometric analysis using the Scopus database. Research articles related to ‘loyalty in the insurance sector research’ were examined using the VOS viewer software. he findings of the research showed that customer loyalty has become an increasingly prominent subject in the context of insurance over time. The study has made use of co-occurrence analysis, bibliographic coupling and publication trends. The top journals, authors, nations, articles and organizations have been identified using bibliometric analysis. This article also includes a presentation of the content analysis of selected articles. iverse studies have been conducted on customer loyalty in various sectors like banking, e-commerce, hospitality and tourism, insurance etc.; however, the goal of the present study is to map the literature on ‘loyalty in the insurance sector’ in Scopus database. This will help to define the main idea and provide the researchers with future research directions. This work will also assist academicians, policy-makers and regulators in understanding the fundamentals of loyalty in the insurance industry and pinpointing the pertinent areas that require further research.
Parent Mediated Interventions for Children with Autism across India: A Qualitative Study
Authors: Rao Vanitha S , Srikanth Nirupama , Santosh Supreeta , Sathya Lakshmi PS  , Athira ND  , Sowmya HR  , Ashok Mysore V  , Raman Vijaya 
Published: February 2024

Background: Lifelong intervention is the mainstay of rehabilitation for individuals on the autism spectrum. The Lancet Commission on care and clinical research on autism has noted the prohibitive cost of intervention services in Low Middle Income Countries and has recommended active involvement of parents in the intervention process. However, there appear to be limited resources for parents to train themselves. The purpose of this qualitative study was to understand the state of Parent Mediated Interventions across India. Method: The study was carried out in two phases. In the first phase, professionals from centers across India were interviewed to understand the methods followed in their centers. In the second phase, focus group discussions were conducted with parents of children on the autism spectrum to understand their needs and challenges in working with their children. The findings from these two phases were then presented to an experienced professionals to corroborate the results. Results: Parent-mediated interventions were found to be limited and relying on manuals published in the West. Parents of children above the age of six continued to face challenges in teaching communication and managing difficult behaviors. Conclusion: Empowering parents by educating them right from the time of diagnosis of the child will ensure better adult outcomes among individuals with autism spectrum disorders.
Construction of a Female Sterility Maintaining System Based on a Novel Mutation of the MEL2 Gene
Authors: Wang Xia , Yuan Shuting , Wang Changjian , Yan Wei , Xie Gang , Wang Cuifang , Qiu Shijun , Wu Jianxin , Deng Xing Wang , Xu Chunjue , Tang Xiaoyan 
Published: February 2024

Abstract
Background
Hybrid rice has significant yield advantage and stress tolerance compared with inbred rice. However, production of hybrid rice seeds requires extensive manual labors. Currently, hybrid rice seeds are produced by crosspollination of male sterile lines by fertile paternal lines. Because seeds from paternal lines can contaminate the hybrid seeds, mechanized production by mixed-seeding and mixed-harvesting is difficult. This problem can be solved if the paternal line is female sterile.

Results
Here we identified a female infertile mutant named h569 carrying a novel mutation (A1106G) in the MEL2 gene that was previously reported to regulate meiosis entry both in male and female organs. h569 mutant is female infertile but male normal, suggesting that MEL2 regulates meiosis entry in male and female organs through distinct pathways. The MEL2 gene and h569 mutant gave us tools to construct female sterility maintaining systems that can be used for propagation of female sterile lines. We connected the wild-type MEL2 gene with pollen-killer gene ZmAA1 and seed-marker gene DsRed2 in one T-DNA cassette and transformed it into ZZH1607, a widely used restorer line. Transgenic line carrying a single transgene inserted in an intergenic region was selected to cross with h569 mutant. F2 progeny carrying homozygous A1106G mutation and hemizygous transgene displayed 1:1 segregation of fertile and infertile pollen grains and 1:1 segregation of fluorescent and non-fluorescent seeds upon self-fertilization. All of the non-fluorescent seeds generated female infertile plants, while the fluorescent seeds generated fertile plants that reproduced in the way as their previous generation.

Conclusions
These results indicated that the female sterility maintaining system constructed in the study can be used to breed and propagate paternal lines that are female infertile. The application of this system will enable mechanized production of hybrid rice seed by using the mixed-seeding and mixed harvesting approach, which will significantly reduce the cost in hybrid rice seed production.
Evaluation of colour vision impairment during acute hypobaric hypoxia in aviation medicine: a randomized controlled trial
Authors: Liebold F. , Adler W. , Jansen S. , Klussmann J. P. , Meyer M. , Nehrlich L. , Schmitz J. , Vingerhoets A. , Heindl L. M. , Hinkelbein J. 
Published: February 2024

AbstractThe digitization of aircraft cockpits places high demands on the colour vision of pilots. The present study investigates colour vision changes upon acute exposure to hypobaric hypoxia. The digital Waggoner Computerized Color Vision Test and the Waggoner D-15 were performed by 54 healthy volunteers in a decompression chamber. Respective altitude levels were sea level, 10,000 or 15,000 ft for exposure periods of 15 and 60 min, respectively. As for 60 min of exposure a significant decrease in colour perception was found between subjects at 15,000 ft as compared to the control group as well as between subjects at 15,000 ft as compared to subjects at 10,000 ft. No significant difference was found in the comparison within the 15,000 ft groups across time points pre-, peri-, and post-exposure. Thus, pilots appear to experience only minor colour vision impairment up to an exposure altitude of 15,000 ft over 60 min of exposure.
Is identification and dissection of the external laryngeal nerve necessary during thyroidectomy? A prospective study
Authors: Bourabaa Soukayna , Settaf Abdellatif 
Published: February 2024

Abstract
Background
Compared to the recurrent laryngeal nerve, the EBSLN (or external laryngeal nerve) is less studied in terms of its course and relationship with the thyroid gland. This is a prospective intraoperative study designed to identify the anatomical variations of the EBSLN in relation to the IPC, the superior thyroid pedicle, and the point where the nerve crosses the STA. Additionally, the study aims to propose a technical procedure for its preservation.

Methods
We conducted a prospective study of 50 patients (total of 100 nerves) undergoing total thyroidectomy at the Department of Surgery ‘B’ in Ibn Sina Hospital, Rabat. Intraoperatively, the EBSLN was visually identified and preserved before ligating the superior thyroid vessels. Each nerve was categorized using established classification systems.

Results
The overall pooled EBSLN identification rate was 82%. Cernea type IIa (nerves crossing the STA less than 1 cm above the upper edge of the superior thyroid pole) and Friedman type II (nerves piercing the lower fibers of the IPC) were the most prevalent (64% and 44%, respectively). Kierner type IV (nerves crossing the branches of the STA immediately above the upper pole of the thyroid gland) was represented in 27% of cases.

Conclusion
A better understanding of surgical anatomy of the neck allows for better results of thyroidectomy by preserving the external and recurrent laryngeal nerves.