bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping individual structural covariance network in development brain with dynamic time warping
Authors: Sun Hui , Sun Qinyao , Li Yuanyuan , Zhang Jiang , Xing Haoyang , Wang Jiaojian 
Published: February 2024

Abstract
A conspicuous property of brain development or maturity is coupled with coordinated or synchronized brain structural co-variation. However, there is still a lack of effective approach to map individual structural covariance network. Here, we developed a novel individual structural covariance network method using dynamic time warping algorithm and applied it to delineate developmental trajectories of topological organizations of structural covariance network from childhood to early adulthood with a large sample of 655 individuals from Human Connectome Project-Development dataset. We found that the individual structural covariance network exhibited small-worldness property and the network global topological characteristics including small-worldness, global efficiency, local efficiency, and modularity linearly increase with age while the shortest path length linearly decreases with age. The nodal topological properties including betweenness and degree increased with age in language and emotion regulation related brain areas, while it decreased with age mainly in visual cortex, sensorimotor area, and hippocampus. Moreover, the topological attributes of structural covariance network as features could predict the age of each individual. Taken together, our results demonstrate that dynamic time warping can effectively map individual structural covariance network to uncover the developmental trajectories of network topology, which may facilitate future investigations to establish the links of structural co-variations with respect to cognition and disease vulnerability.
The shorter a man is, the more he defends fairness: relative height disadvantage promoting third-party punishment—evidence from inter-brain synchronization
Authors: Meng Yujia , Jia Shuyu , Liu Jingyue , Zhang Chenyu , Wang He , Liu Yingjie 
Published: February 2024

Abstract
Third-party punishment occurs in interpersonal interactions to sustain social norms, and is strongly influenced by the characteristics of the interacting individuals. During social interactions, height is the striking physical appearance features first observed, height disadvantage may critically influence men’s behavior and mental health. Herein, we explored the influence of height disadvantage on third-party punishment through time-frequency analysis and electroencephalography hyperscanning. Two participants were randomly designated as the recipient and third party after height comparison and instructed to complete third-party punishment task. Compared with when the third party’s height is higher than the recipient’s height, when the third party’s height is lower, the punishment rate and transfer amount were significantly higher. Only for highly unfair offers, the theta power was significantly greater when the third party’s height was lower. The inter-brain synchronization between the recipient and the third party was significantly stronger when the third party’s height was lower. Compared with the fair and medium unfair offers, the inter-brain synchronization was strongest for highly unfair offers. Our findings indicate that the height disadvantage-induced anger and reputation concern promote third-party punishment and inter-brain synchronization. This study enriches research perspective and expands the application of the theory of Napoleon complex.
SEPDB: a database of secreted proteins
Authors: Wang Ruiqing , Ren Chao , Gao Tian , Li Hao , Bo Xiaochen , Zhu Dahai , Zhang Dan , Chen Hebing , Zhang Yong 
Published: February 2024

Abstract
Detecting changes in the dynamics of secreted proteins in serum has been a challenge for proteomics. Enter secreted protein database (SEPDB), an integrated secretory proteomics database offering human, mouse and rat secretory proteomics datasets collected from serum, exosomes and cell culture media. SEPDB compiles secreted protein information from secreted protein database, UniProt and Human Protein Atlas databases to annotate secreted proteomics data based on protein subcellular localization and disease markers. SEPDB integrates the latest predictive modeling techniques to measure deviations in the distribution of signal peptide structures of secreted proteins, extends signal peptide sequence prediction by excluding transmembrane structural domain proteins and updates the validation analysis pipeline for secreted proteins. To establish tissue-specific profiles, we have also created secreted proteomics datasets associated with different human tissues. In addition, we provide information on heterogeneous receptor network organizational relationships, reflective of the complex functional information inherent in the molecular structures of secreted proteins that serve as ligands. Users can take advantage of the Refreshed Search, Analyze, Browse and Download functions of SEPDB, which is available online at https://sysomics.com/SEPDB/.
Database URL: https://sysomics.com/SEPDB/
Risks and benefits of sharing patient information on social media: a digital dilemma
Authors: van der Boon Robert M A , Camm A John , Aguiar C , Biasin E , Breithardt G , Bueno H , Drossart I , Hoppe N , Kamenjasevic E , Ladeiras-Lopes R , McGreavy Paul , Lanzer P , Vidal-Perez R , Bruining Nico 
Published: February 2024

Abstract
Social media (SoMe) has witnessed remarkable growth and emerged as a dominant method of communication worldwide. Platforms such as Facebook, X (formerly Twitter), LinkedIn, Instagram, TikTok, and YouTube have become important tools of the digital native generation. In the field of medicine, particularly, cardiology, attitudes towards SoMe have shifted, and professionals increasingly utilize it to share scientific findings, network with experts, and enhance teaching and learning. Notably, SoMe is being leveraged for teaching purposes, including the sharing of challenging and intriguing cases. However, sharing patient data, including photos or images, online carries significant implications and risks, potentially compromising individual privacy both online and offline. Privacy and data protection are fundamental rights within European Union treaties, and the General Data Protection Regulation (GDPR) serves as the cornerstone of data protection legislation. The GDPR outlines crucial requirements, such as obtaining ‘consent’ and implementing ‘anonymization’, that must be met before sharing sensitive and patient-identifiable information. Additionally, it is vital to consider the patient’s perspective and prioritize ethical and social considerations when addressing challenges associated with sharing patient information on SoMe platforms. Given the absence of a peer-review process and clear guidelines, we present an initial approach, a code of conduct, and recommendations for the ethical use of SoMe. In conclusion, this comprehensive review underscores the importance of a balanced approach that ensures patient privacy and upholds ethical standards while harnessing the immense potential of SoMe to advance cardiology practice and facilitate knowledge dissemination.
High diversity, abundance, and expression of hydrogenases in groundwater
Authors: Li Shengjie , Mosier Damon , Kouris Angela , Humez Pauline , Mayer Bernhard , Strous Marc , Diao Muhe 
Published: February 2024

Abstract
Hydrogen may be the most important electron donor available in the subsurface. Here we analyse the diversity, abundance and expression of hydrogenases in 5 proteomes, 25 metagenomes, and 265 amplicon datasets of groundwaters with diverse geochemistry. A total of 1545 new [NiFe]-hydrogenase gene sequences were recovered, which considerably increased the number of sequences (1999) in a widely used database. [NiFe]-hydrogenases were highly abundant, as abundant as the DNA-directed RNA polymerase. The abundance of hydrogenase genes increased with depth from 0 to 129 m. Hydrogenases were present in 481 out of 1245 metagenome-assembled genomes. The relative abundance of microbes with hydrogenases accounted for ~50% of the entire community. Hydrogenases were actively expressed, making up as much as 5.9% of methanogen proteomes. Most of the newly discovered diversity of hydrogenases was in “Group 3b”, which has been associated with sulfur metabolism. “Group 3d”, facilitating the interconversion of electrons between hydrogen and NAD, was the most abundant and mainly observed in methanotrophs and chemoautotrophs. “Group 3a”, associated with methanogenesis, was the most abundant in proteomes. Two newly discovered groups of [NiFe]-hydrogenases, observed in Methanobacteriaceae and Anaerolineaceae, further expanded diversity. Our results highlight the vast diversity, abundance and expression of hydrogenases in groundwaters, suggesting a high potential for hydrogen oxidation in subsurface habitats.
Can feature structure improve model’s precision? A novel prediction method using artificial image and image identification
Authors: He Yupeng , Sun Qiwen , Matsunaga Masaaki , Ota Atsuhiko 
Published: February 2024

Abstract

Objectives
This study aimed to develop an approach to enhance the model precision by artificial images.

Materials and Methods
Given an epidemiological study designed to predict 1 response using f features with M samples, each feature was converted into a pixel with certain value. Permutated these pixels into F orders, resulting in F distinct artificial image sample sets. Based on the experience of image recognition techniques, appropriate training images results in higher precision model. In the preliminary experiment, a binary response was predicted by 76 features, the sample set included 223 patients and 1776 healthy controls.

Results
We randomly selected 10 000 artificial sample sets to train the model. Models’ performance (area under the receiver operating characteristic curve values) depicted a bell-shaped distribution.

Conclusion
The model construction strategy developed in the research has potential to capture feature order related information and enhance model predictability.
Evaluation of the Canadian approved drug screening equipment cut-off levels for tetrahydrocannabinol (THC)
Authors: Copley Heather , Filbert Angela , Williams Kali 
Published: February 2024

Abstract
In 2018, Canada introduced roadside oral fluid (OF) screening devices, called Approved Drug Screening Equipment (ADSE), as an investigative tool in impaired driving investigations to detect tetrahydrocannabinol (THC), cocaine and/or methamphetamine in drivers. In this work, we compare the detection and concentration of THC in blood samples collected from suspected impaired drivers that tested positive at the roadside for THC on an ADSE. The two ADSEs that were utilized were the Dräger DrugTest® 5000 (DDT) and the Abbott SoToxa™ (SoToxa), both configured with a THC OF concentration cut-off concentration of 25 ng/mL. Blood samples were screened for cannabinoids using immunoassay and positive results were followed up by confirmation/quantitation of THC by ultra-performance liquid chromatography with tandem mass spectrometry (UPLC–MS-MS). A total of 230 cases were available where a blood sample was collected from a suspected impaired driver subsequent to a positive THC screen result on an ADSE. The blood samples were taken an average of 1.4 hours (range = 9 minutes to 3.2 hours) after the ADSE test. THC was confirmed in 98% of blood samples with concentrations across all samples ranging from not detected (cut = off 0.5 ng/mL) to greater than 20 ng/mL. Further, 90% of the blood samples had a THC concentration of 2.0 ng/mL (the lower per se limit in Canada) or greater. A positive ADSE test of a suspected impaired driver may predict that the driver has a detectable level of THC in their blood, and there is a high likelihood that the THC blood concentration is 2.0 ng/mL or higher. Hence, ADSE may be a useful tool for law enforcement and aid in the development of grounds to believe that a driver is operating a conveyance with a THC concentration exceeding Canadian per se limits.
Description of a new species of Forcipomyia (Lasiohelea) (Diptera: Ceratopogonidae) and a key to species of the F. (L.) taiwana species group in China
Authors: Zhang Yu Ling , Jiang Xiao Hong , Hou Xiao Hui 
Published: February 2024

Abstract
Forcipomyia (Lasiohelea) (Meigen, Diptera: Ceratopogonidae) penguin sp. nov. is described and illustrated based on male specimens from China. It is characterized by the approximately rectangular aedeagus, which is longitudinally split in the middle, with the apices slightly bending to the outside, making it into the shape of a hook; bilobed aedeagus is very closely connected. The description is provided using scanning electron microscopes, light microscopes, and camera lucida drawing. The specimens were collected from woods near a pond in Liping County, Guizhou Province. We provide both keys to male and female of Forcipomyia (Lasiohelea) taiwana species group in China.
Impact of incidental synucleinopathy in mild cognitive impairment due to Alzheimer disease
Authors: Shriram Jahnavi , Malek-Ahmadi Michael , Irwin Chase , Sabbagh Marwan 
Published: February 2024

Abstract
Recent evidence suggests that the presence of α-synuclein Lewy bodies (LBs) correlates with accelerated disease progression in patients with Alzheimer disease (AD) but it is unclear whether this effect is also exerted in the mild cognitive impairment (MCI) phase of AD. We sought to determine whether incidental LB pathology in patients with MCI due to AD is associated with a faster rate of cognitive decline compared to MCI controls without LB pathology. We identified patients within the National Alzheimer’s Coordinating Center (NACC) database with MCI due to AD and stratified the cohort by the presence or absence of synucleinopathy. We utilized a repeated measures longitudinal analysis of Mini-Mental State Examination (MMSE) scores to determine whether the decline in performance occurred at a greater rate in the synucleinopathy patients. A total of 206 participants were studied; 80 had coincident synucleinopathy. The rate of decline in MMSE scores between the groups did not differ. This may suggest that a synergistic effect of LB and AD neuropathology is only appreciable in the later stages of disease progression. Further investigation into the effect of mixed LB and AD pathology in the early stages of cognitive impairment is warranted to highlight opportunities for targeted early intervention in patients.
How shared ties and journalistic cultures shape global news coverage of disruptive media events: the case of the 9/11 terror attacks
Authors: Jungblut Marc , Althaus Scott , Bajjalieh Joseph , Chan Chung-hong , Welbers Kasper , van Atteveldt Wouter , Wessler Hartmut 
Published: February 2024

Abstract
In recent decades, disruptive media events, such as major terrorist attacks, have gained increasing relevance in news coverage around the world. Despite the growing importance of such globally broadcast media events, little research to date has examined cross-national variation in event coverage or the predictors of this variation. This study examines news coverage about the 9/11 terror attacks in the United States across 51 countries to analyze whether the topical focus and emotional tone of news coverage about the attacks varied according to a country’s proximity to the United States and the dominant role perceptions of its journalistic culture. We show that these macro-level predictors are associated in varying degrees with the country-level topical focus and emotional tone of reporting over the 30 days following this salient event. Moreover, our analysis also suggests that temporal developments may have uniformly structured much of this worldwide coverage.
The one-sayers model for the Extended Crosswise design
Authors: Cruyff Maarten J L F , Sayed Khadiga H A , Petróczi Andrea , van der Heijden Peter G M 
Published: February 2024

Abstract
The Extended Crosswise design is a randomized response design characterized by a sensitive and an innocuous question and two sub-samples with complementary randomization probabilities of the innocuous question. The response categories are ‘One’ with two different answers and ‘Two’ with two answers that are the same. Due to the complementary randomization probabilities, ‘One’ is the incriminating response in one sub-sample, and ‘Two’ in the other. The use of two sub-samples generates a degree of freedom to test for response biases with a goodness-of-fit test, but this test is unable to detect bias resulting from self-protective respondents giving the non-incriminating response when the incriminating response was required. This raises the question what a significant goodness-of-fit test measures? In this paper, we hypothesize that respondents are largely unaware which response is associated with the sensitive characteristic, and intuitively perceive ‘One’ as the safer response. We present empirical evidence for one-saying in six surveys among a total of 4,242 elite athletes, and present estimates of doping use corrected for it. Furthermore, logistic regression analyses are conducted to test the hypothesis that respondents who complete the survey in a short time are more likely to answer randomly, and therefore are less likely to be one-sayers.
Anti-E alloimmunization from a platelet apheresis transfusion in a 22-month-old male with acute myeloid leukemia
Authors: Burks Martin , Warren Christina S , Lightfoot Thomas , Fadeyi Emmanuel A 
Published: February 2024

Abstract
RhD alloimmunization from platelet transfusions have been documented in the literature. However, non-RhD platelet alloimmunization is much less frequent and the risk for non-RhD alloimmunization from platelets is thought to be extremely low and most associated with buffy coat pooled platelets. A 22-month-old male with acute myeloid leukemia received 99 mL apheresis platelets for thrombocytopenia. Three months later, an antibody screen, the direct antiglobulin test (DAT), and red blood cell (RBC) genotype were sent for laboratory evaluation. The antibody screen was positive, with anti-E identified. The DAT was negative and the RBC genotype of the patient was predicted to be negative for the E antigen whereas the platelet donor was predicted to be positive for E antigen. There is a risk of alloimmunization of non-RhD antigen from platelet pheresis transfusion even in a patient less than 2 years old.
Poaceae plants transfer cyclobutane pyrimidine dimer photolyase to chloroplasts for ultraviolet-B resistance
Authors: Otake Momo , Teranishi Mika , Komatsu Chiharu , Hara Mamoru , Yoshiyama Kaoru Okamoto , Hidema Jun 
Published: February 2024

Abstract
Photoreactivation enzyme that repairs cyclobutane pyrimidine dimer (CPD) induced by ultraviolet-B radiation, commonly called CPD photolyase (PHR) is essential for plants living under sunlight. Rice (Oryza sativa) PHR (OsPHR) is a unique triple-targeting protein. The signal sequences required for its translocation to the nucleus or mitochondria are located in the C-terminal region but have yet to be identified for chloroplasts. Here, we identified sequences located in the N-terminal region, including the serine-phosphorylation site at position 7 of OsPHR, and found that OsPHR is transported/localized to chloroplasts via a vesicle transport system under the control of serine-phosphorylation. However, the sequence identified in this study is only conserved in some Poaceae species, and in many other plants, PHR is not localized to the chloroplasts. Therefore, we reasoned that Poaceae species need the ability to repair CPD in the chloroplast genome to survive under sunlight and have uniquely acquired this mechanism for PHR chloroplast translocation.
Abscisic acid root-to-shoot translocation by transporter AtABCG25 mediates stomatal movements in Arabidopsis
Authors: Yang Qin , Deng Xiaojuan , Liu Ting , Qian Jiayun , Zhang Penghong , Zhu Engao , Wang Jingqi , Zhu Xiaoxian , Kudoyarova Guzel , Zhao Jiangzhe , Zhang Kewei 
Published: February 2024

Abstract
The phytohormone abscisic acid (ABA) plays a central role in regulating stomatal movements under drought conditions. The root-derived peptide CLAVATA3/EMBRYO SURROUNDING REGION-RELATED 25 (CLE25) moves from the root to shoot for activating ABA biosynthesis under drought conditions. However, the root-to-shoot translocation of root-derived ABA and its regulation of stomatal movements in the shoot remain to be clarified. Here, we reveal that the ABA transporter ATP-binding cassette subfamily G member 25 (AtABCG25) mediates root-to-shoot translocation of ABA and ABA-glucosyl ester (ABA-GE) in Arabidopsis (Arabidopsis thaliana). Isotope-labeled ABA tracer experiments and hormone quantification in xylem sap showed that the root-to-shoot translocation of ABA and ABA-GE was substantially impaired in the atabcg25 mutant under nondrought and drought conditions. However, the contents of ABA and ABA-GE in the leaves were lower in the atabcg25 mutant than in the wild type (WT) under nondrought but similar under drought conditions. Consistently, the stomatal closure was suppressed in the atabcg25 mutant under nondrought but not under drought conditions. The transporter activity assays showed that AtABCG25 directly exported ABA and ABA-GE in planta and in yeast (Saccharomyces cerevisiae) cells. Thus, we proposed a working model in which root-derived ABA transported by AtABCG25 via xylem mediates stomatal movements in the shoot under nondrought conditions but might exhibit little effect on stomatal movements under drought conditions. These findings extend the functions of AtABCG25 and provide insights into the long-distance translocation of ABA and its role in stomatal movements.
Superstition in Surgery: A Population-Based Cohort Study to Assess the Association Between Surgery on Friday the 13th and Postoperative Outcomes
Authors: Ranganathan Sanjana , Riveros Carlos , Geng Michael , Chang Courtney , Tsugawa Yusuke , Ravi Bheeshma , Melchiode Zachary , Hu Siqi , Kobashi Kathleen , Miles Brian J. , Klaassen Zachary , Nathens Avery , Coburn Natalie , Detsky Allan S. , Jerath Angela , Wallis Christopher J. D. , Satkunasivam Raj 
Published: February 2024

Objective:
We sought to examine whether the outcomes of patients who receive a surgical procedure on Friday the 13th differ from patients who receive surgery on flanking Fridays.

Background:
Numerous studies have demonstrated that increased anxiety from the provider or patient around the time of surgery can lead to worse outcomes. Superstitious patients often express significant concern and anxiety when undergoing a surgical procedure on Friday the 13th.

Methods:
A retrospective, population-based cohort study of 19,747 adults undergoing 1 of 25 common surgical procedures on Friday the 13th or flanking control Fridays (Friday the 6th and Friday the 20th) between January 1, 2007, and December 31, 2019, with 1 year of follow-up. The main outcomes included death, readmission, and complications at 30 days (short-term), 90 days (intermediate-term), and 1 year (long-term).

Results:
A total of 7,349 (37.2%) underwent surgery on Friday the 13th, and 12,398 (62.8%) underwent surgery on a flanking Friday during the study period. Patient characteristics were similar between the 2 groups. We found no evidence that patients receiving surgery on Friday the 13th group were more likely to experience the composite primary outcome at 30 days [adjusted odds ratio (aOR) = 1.02 (95% CI = 0.94–1.09)], 90 days [aOR = 0.97 (95% CI = 0.90–1.04)], and 1 year [aOR = 0.99 (95% CI = 0.94–1.04)] after surgery.

Conclusion:
Patients receiving surgery on Friday the 13th do not appear to fare worse than those treated on ordinary Fridays with respect to the composite outcome.