bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized clinical trial of preoperative intranasal mupirocin to reduce surgical-site infection after digestive surgery
Authors: Suzuki Y , Kamigaki T , Fujino Y , Tominaga M , Ku Y , Kuroda Y 
Published: August 2003

Abstract

Background
Compromised patients subjected to major digestive surgery frequently develop infective complications caused by methicillin-resistant Staphylococcus aureus (MRSA), which may have dangerous consequences. This was a prospective randomized study to determine whether intranasal mupirocin could reduce postoperative infective complications in patients having digestive surgery.

Methods
A total of 395 patients who underwent abdominal digestive surgery were assigned randomly into two groups: a treated group (193 patients) and controls (202). Patients in the treated group were given 30 mg mupirocin calcium hydrate ointment topically to each nostril three times a day on each of the 3 days before operation. The untreated group received no mupirocin treatment.

Results
Most infections were due to Gram-negative bacteria in both groups. There were 21 Gram-positive infections detected at the surgical site, ten in the treated group and 11 in control patients. The incidence of pneumonia was significantly different between the groups (none in the treated group and five in control patients; P = 0·028). Four of five patients with pneumonia had a sputum culture containing MRSA.

Conclusion
Intranasal mupirocin treatment had no significant impact on surgical-site infection after digestive surgery.
Irish child sexual abuse victims attending a specialist centre
Authors: O'Riordan Beth , Carr Alan , Turner Rhonda 
Published: August 2003

AbstractWe profiled a cohort of CSA cases referred for assessment to a specialist child sexual abuse (CSA) centre in a national paediatric hospital in Ireland. Historical and clinical data were drawn from records of 171 cases. The majority of cases were referred by social workers following purposeful disclosure of CSA. Three quarters of the cases were female with a mean age of 9 years. They were from a wide spectrum of socioeconomic groups and many had suffered a range of family adversities. In most cases, the abuse involved masturbation of the child by the abuser. Almost all of the perpetrators were male with a mean age of 28 years and in 60% of cases extrafamilial abuse had occurred. In 23% of cases, the perpetrator had a history of previous sexual offending. Anxiety was the most common emotional problem before disclosure and after disclosure the most common emotional problem was guilt. Before disclosure school refusal was the most common behavioural problem and after disclosure fighting was the most prevalent behavioural difficulty. The most common factors supporting the credibility of CSA allegations were labile mood, the child's ability to differentiate fact from fantasy and a detailed disclosure of contextual details. More adolescents showed deterioration in schoolwork after disclosure and for more pre school children clinginess following disclosure was a significant emotional problem. More primary school aged children were abused by perpetrators who had abused a number of children. For children abused by such perpetrators, vaginal intercourse was less common. Vaginal intercourse was more common in 6–11‐year‐old victims and those who were abused on a daily basis. The threat that disclosure posed to the integrity of the family structure was more often a factor hindering disclosure in victims abused by father figures and abused very frequently. Copyright © 2003 John Wiley & Sons, Ltd.
Working in partnership: the development of a home visiting service for vulnerable families
Authors: Barlow Jane , Stewart‐Brown Sarah , Callaghan Helen , Tucker Joanna , Brocklehurst Neil , Davis Hilton , Burns Claire 
Published: August 2003

AbstractThe primary prevention of child abuse is both a clinical and political priority. Home visiting programmes consisting of structured visits by a professional over an extended period of time during the perinatal period have been identified in a number of studies as being a potentially effective means of achieving this. The use of professionally delivered home visiting programmes in the UK to date, however, has been limited. This paper describes the development of an innovative, primary care‐based home visiting service, which is aimed at the primary prevention of maltreatment, abuse and neglect and the promotion of positive parenting and secure attachment. The paper provides a description of the rationale and policy context for the new service and an account of its development, with particular emphasis on the aim of working ‘in partnership’ with families. Copyright © 2003 John Wiley & Sons, Ltd.
The Triple P‐Positive Parenting Programme: a universal population‐level approach to the prevention of child abuse
Authors: Sanders Matthew R. , Cann Warren , Markie‐Dadds Carol 
Published: August 2003

AbstractThe Triple P‐Positive Parenting Programme is described as an example of an evidence‐based universal parenting initiative that provides a tiered continuum of interventions of increasing strength but narrowing reach in an effort to make parenting programmes more accessible to parents. Interventions within the system range from the use of the media and brief messages to intensive family interventions for parents where parenting problems are complicated by multiple additional sources of family adversity. Several issues concerning the role of training and organizational factors that influence the successful uptake and implementation of the programme are discussed. Copyright © 2003 John Wiley & Sons, Ltd.
Alternative therapeutic strategies for patients with severe end‐stage coronary artery disease not amenable to conventional revascularization
Authors: Almeda Francis Q. , Parrillo Joseph E. , Klein Lloyd W. 
Published: August 2003

AbstractAlthough there have been remarkable advances in medical therapy, percutaneous coronary interventions, and coronary artery bypass graft surgery, complete revascularization remains a challenge given the more complex coronary artery disease prevalent in contemporary practice. The lack of donors for cardiac transplantation will fuel the search for effective alternative strategies for dealing with patients with severe ischemic heart disease not amenable to conventional revascularization techniques. Percutaneous laser revascularization clearly diminishes anginal symptoms; however, the blinded trials have provided conflicting results, with one study showing a definite decrease in angina and another suggesting that the placebo effect may play a major role in this modality. Similarly, surgical transmyocardial laser revascularization is limited by the lack of consistent improvement in objective measurements of ischemia and the potential confounding mechanisms of denervation and the placebo effect, and thus should be reserved for only the most highly selected patients. Although enhanced external counterpulsation is associated with an improvement in anginal symptoms and exercise tolerance, this modality is limited by its availability, tolerability, and rigid exclusion criteria. Of the alternative strategies available, therapeutic angiogenesis holds the most promise. However, the long‐term results of ongoing randomized clinical trials require further scrutiny. Novel methods for vascular reconstruction are evolving techniques, but should be viewed currently as mainly experimental methods. The common goals of these new treatment options would be to reduce symptoms, decrease morbidity, and potentially improve mortality by reducing ischemia through favorably impacting myocardial oxygen supply and demand. The optimal management of patients with severe end‐stage coronary artery disease not amenable to conventional revascularization techniques will continue to remain a challenge for the clinician and will be the main focus of basic cardiovascular research and clinical trials in the new millennium. Catheter Cardiovasc Interv 2003;60:57–66. © 2003 Wiley‐Liss, Inc.
Reproducibility of coronary lumen, plaque, and vessel wall reconstruction and of endothelial shear stress measurements in vivo in humans
Authors: Coskun Ahmet U. , Yeghiazarians Yerem , Kinlay Scott , Clark Maureen E. , Ilegbusi Olusegun J. , Wahle Andreas , Sonka Milan , Popma Jeffrey J. , Kuntz Richard E. , Feldman Charles L. , Stone Peter H. 
Published: August 2003

AbstractThe purpose of this study was to assess the reproducibility of an in vivo methodology to reconstruct the lumen, plaque, and external elastic membrane (EEM) of coronary arteries and estimate endothelial shear stress (ESS). Ten coronary arteries without significant stenoses (five native and five stented arteries) were investigated. The 3D lumen and EEM boundaries of each coronary artery were determined by fusing end‐diastolic intravascular ultrasound images with biplane coronary angiograms. Coronary flow was measured. Computational fluid dynamics was used to calculate local ESS. Complete data acquisition was then repeated. Analysis was performed on each data set in a blinded manner. The intertest correlation coefficients for all arteries for the two measurements of lumen radius, EEM radius, plaque thickness, and ESS were r = 0.96, 0.96, 0.94, 0.91, respectively (all P values < 0.0001). The 3D anatomy and ESS of human coronary arteries can be reproducibly estimated in vivo. This methodology provides a tool to examine the effect of ESS on atherogenesis, remodeling, and restenosis; the contribution of arterial remodeling and plaque growth to changes in the lumen; and the impact of new therapies. Catheter Cardiovasc Interv 2003;60:67–78. © 2003 Wiley–Liss, Inc.
Gold coating and restenosis after primary stenting of ostial renal artery stenosis
Authors: Zeller Thomas , Müller Christian , Frank Ulrich , Bürgelin Karlheinz , Sinn Lutz , Horn Barbara , Roskamm Helmut 
Published: August 2003

AbstractPredictors of restenosis after stent angioplasty of ostial renal artery stenosis (RAS) and long‐term technical success, particularly the influence of gold coating, are unknown. During a 4‐year period (1996–2000), we treated 156 consecutive patients with 219 ostial RAS of ≥ 70% diameter stenosis. Gold‐coated stents were used in 29% of RAS (n = 64); the vessel diameter ranged from 3 to 9 mm. The restenosis rate was 11.4% at 12 months, 12.2% for gold‐coated stents and 11.1% for noncoated stents. Restenosis rates were 16% for ≤ 4 mm, 17% for 5 mm, 10% for 6 mm, and 0% for ≥ 7 mm (P ≤ 0.05). In a backward stepwise logistic regression analysis including gold coating, vessel diameter, gender, diabetes, smoking status, as well as lesion diameter stenosis before and after stenting, vessel diameter was found the only independent predictor of restenosis (odds ratio = 0.57; 95% CI = 0.35–0.93; P = 0.02, for an increase in vessel diameter of 1 mm). Gold coating was not a significant predictor (odds ratio = 1.09; 95% CI = 0.39–3.03; P = 0.87). Seven major (4.5%) complications occurred. There were no procedural fatalities. The restenosis rate after stent angioplasty of ostial RAS is influenced by the vessel diameter but not by gold coating. Catheter Cardiovasc Interv 2003;60:1–6. © 2003 Wiley–Liss, Inc.
Feasibility and safety of immediate perioperative implantation of intravascular stents in cavopulmonary pathways
Authors: Walayat Muhammad , McArthur Kenneth , Lilley Stuart , Wilson Neil 
Published: August 2003

AbstractFontan‐type procedures are widely used for palliation of patients with many forms of a functional univentricular heart. An ideal Fontan circuit should be free of any distortion or stenosis. The use of stents for the treatment of stenotic and hypoplastic vessels is well established in pediatric cardiac practice. We report the successful use of endovascular stents during the immediate postoperative period in patients undergoing cavopulmonary anastomoses. Catheter Cardiovasc Interv 2003;60:94–98. © 2003 Wiley‐Liss, Inc.
Superior vena cava syndrome secondary to saphenous venous graft aneurysm with right atrial fistula
Authors: Fares Wassim , Sharifi Mohsen , Steele Robert , Sarhill Nabeel , Sopko Joseph , Ramana C.V. , Koch J. Michael 
Published: August 2003

AbstractMega‐aneurysms of saphenous vein grafts (SVGs) to coronary arteries are rare complications of bypass surgery. We report the development of superior vena cava syndrome secondary to an SVG mega‐aneurysm with concomitant fistulous communication to the right atrium. Successful treatment was achieved by coil embolization and chronic anticoagulation. Catheter Cardiovasc Interv 2003;60:45–47. © 2003 Wiley–Liss, Inc.
Recanalization of a discrete atretic right pulmonary artery segment with a new radiofrequency system
Authors: Pedra Carlos A.C. , Filho Ronaldo Mont'Alverne , Arrieta Raul S. , Tellez Ricardo , Fontes Valmir F. 
Published: August 2003

AbstractWe describe a case in which a discrete atretic segment of the right pulmonary artery (due to a Blalock‐Taussig shunt) was reconstructed using a new radiofrequency system, balloon dilation, and stent implantation in an 18‐month‐old patient. The shunt was coil‐occluded. The technique and applications of this novel approach are discussed. Catheter Cardiovasc Interv 2003;60:82–87. © 2003 Wiley–Liss, Inc.
Use of balloon pull‐through technique to assist in CardioSEAL device closure of patent foramen ovale
Authors: Chintala Kavitha , Turner Daniel R. , Leaman Stephanie , Rodriguez‐Cruz Edwin , Wynne Joshua , Greenbaum Adam , Forbes Thomas J. 
Published: August 2003

AbstractCardioSEAL device closure of patent foramen ovale (PFO) has been advocated for the treatment of patients with cryptogenic stroke. Using the standard delivery technique, partial deployment of the CardioSEAL device can occur, especially in patients with a thick septum secundum and/or long PFO tunnel. We hypothesized that using a left atrial‐to‐right atrial balloon pull‐through to make the septum primum incompetent would result in improved final device position regardless of septal thickness or tunnel length. Catheterization reports, cineangiograms, and transesophageal echocardiograms of 51 patients who underwent CardioSEAL device closure of PFO between March 2000 and August 2002 were retrospectively reviewed. Group 1 (n = 21) included patients with CardioSEAL placement using the standard technique and group 2 (n = 30) included patients with CardioSEAL placement using the balloon pull‐through technique. There were no differences between the groups in terms of age (43.6 vs. 45.3 years; P = NS), weight (83.3 vs. 89.9 kg; P = NS), septum secundum thickness (6.4 vs. 7.0 mm; P = NS), PFO tunnel length (15.5 vs. 13.1 mm; P = NS), or device size. In group 1, 4/21 (19%) had partial deployment of the CardioSEAL device, while in group 2, no partial CardioSEAL deployment (0/30) was observed. No complications were associated with the balloon pull‐through technique. We conclude that the left atrial‐to‐right atrial balloon pull‐through technique is safe and may allow for better final position of the CardioSEAL device during PFO closure. Catheter Cardiovasc Interv 2003;60:101–106. © 2003 Wiley–Liss, Inc.
Fenestrated Amplatzer device for percutaneous creation of interatrial communication in patients after Fontan operation
Authors: Chatrath Ritu , Cabalka Allison K. , Driscoll David J. , Hagler Donald J. 
Published: August 2003

AbstractA customized Amplatzer septal device with a 5 mm fenestration was used to create an interatrial communication in two patients with previous Fontan operation and clinical indication for fenestration. At follow‐up, device fenestration was occluded in both patients. In both patients, the device fenestration was reopened and patency maintained by placement of two stents within the communicating channel. Catheter Cardiovasc Interv 2003;60:88–93. © 2003 Wiley–Liss, Inc.
Radiofrequency perforation in the treatment of acquired left pulmonary artery atresia following repair of tetralogy of Fallot
Authors: Kort Henry W. , Balzer David T. 
Published: August 2003

AbstractAcquired pulmonary artery discontinuity can complicate operative repair of certain congenital heart defects. We describe successful recanalization of acquired left pulmonary artery atresia using radiofrequency energy in a 14‐month‐old child who had previously undergone repair of tetralogy of Fallot with pulmonary atresia. Catheter Cardiovasc Interv 2003;60:79–81. © 2003 Wiley–Liss, Inc.
Transbrachial insertion of an intra‐aortic balloon pump for complex coronary angioplasty
Authors: Noël Bernard M. , Gleeton Onil , Barbeau Gérald R. 
Published: August 2003

AbstractTransfemoral insertion of intra‐aortic balloon pump (IABP) for hemodynamic support is a useful adjunct in patients undergoing complex percutaneous revascularization procedures. However, this approach is not always possible, particularly in patients with severe occlusive peripheral vascular disease. We describe the first reported case of insertion of IABP through the brachial artery. Catheter Cardiovasc Interv 2003;60:36–39. © 2003 Wiley–Liss, Inc.
Intracoronary radiation to treat in‐stent restenosis in six cardiac transplant patients
Authors: Grise Mark A. , Reilly John P. , Tobis Jonathan M. , Takano Yuzuru , Currier Jesse W. , Kobashigawa Jon A. , Weisz Giora , Moses Jeffrey W. , Leon Martin B. , Yeung Alan , Teirstein Paul S. 
Published: August 2003

AbstractTransplant vasculopathy significantly limits the survival of cardiac transplant patients and occurs in 50% of patients by 5 years posttransplant. We report our experience with six cardiac transplant patients who underwent intracoronary brachytherapy for in‐stent restenosis. At four centers, six patients underwent intracoronary radiation for in‐stent restenosis. All patients received extended antiplatelet therapy with clopidogrel and aspirin. Follow‐up angiography was performed in all patients. Two of the six patients underwent subsequent target lesion revascularization. Patient 1 presented with total occlusion of her radiated lesion. She had a complex procedure requiring stenting for a dissection after the radiation dwell. Patient 2 had high‐grade restenosis following brachytherapy. Patient 3 had a 50% restenotic lesion. Patients 4, 5, and 6 had follow‐up angiography that showed no evidence of restenosis. There are few good options to treated accelerated transplant vasculopathy. Radiation therapy may be a viable option in this difficult patient population. Catheter Cardiovasc Interv 2003;60:41–44. © 2003 Wiley–Liss, Inc.
ST segment elevation in leads V1 to V3 due to isolated right ventricular branch occlusion during primary right coronary angioplasty
Authors: Acikel Mahmut , Yilmaz Mustafa , Bozkurt Engin , Gürlertop Yekta , Köse Nuri 
Published: August 2003

AbstractIt is rare to observe ST elevation in anterior derivations caused by isolated right ventricular branch occlusion. We described the case with acute inferior and right ventricular myocardial infarction (MI) who developed ST segment elevation in precordial leads V1 to V3 due to isolated right ventricular branch occlusion during primary right coronary angioplasty. Catheter Cardiovasc Interv 2003;60:32–35. © 2003 Wiley–Liss, Inc.
Sonotherapy, antirestenotic therapeutic ultrasound in coronary arteries: The first clinical experience
Authors: Regar E. , Thury A. , van der Giessen W.J. , Sianos G. , Vos J. , Smits P.C. , Carlier S.G. , de Feyter P. , Foley D.P. , Serruys Patrick W. 
Published: August 2003

AbstractWe studied the safety and feasibility of intracoronary sonotherapy (IST) and its effect on the coronary vessel at 6 months. Thirty‐seven patients with stable or unstable angina were included (40 lesions). The indication was de novo lesion (n = 26), restenosis (n = 2), in‐stent restenosis (n = 11), and a total occlusion of a venous bypass graft. After successful angioplasty, IST was performed using a 5 Fr catheter with three serial ultrasound transducers operating at 1 MHz. IST was successfully performed in 36 lesions (success rate, 90%). IST exposure time per lesion was 718 ± 127 sec. During hospital stay, one patient died due to a bleeding complication. At 6‐month follow‐up, one patient experienced acute myocardial infarction, eight patients underwent repeat PTCA. No patient underwent CABG. Late lumen loss was 1.05 ± 0.70 mm with a restenosis rate of 25%. IVUS analysis revealed a neointima burden of 25% ± 11%. IST can be applied safely and with high acute procedural success. Sonotherapy‐related major adverse events were not observed. Late lumen loss and neointimal growth were similar to conventional PTCA approaches. These results justify the initiation of randomized clinical efficacy studies. Catheter Cardiovasc Interv 2003;60:9–17. © 2003 Wiley–Liss, Inc.
Feasibility and safety of day‐case transfemoral coronary stenting
Authors: Dalby Miles , Davies Justin , Rakhit Roby , Mayet Jamil , Foale Rodney , Davies D. Wyn 
Published: August 2003

AbstractPercutaneous coronary intervention (PCI) is usually followed by overnight observation. In order to increase activity from a limited bed base, we planned to discharge a cohort of patients undergoing uncomplicated PCI procedures on the same day. Seventy patients considered suitable for same‐day discharge underwent PCI procedures and a 100% stent rate was planned with device closure of the arterial access site. Procedural success was achieved in 68 (97%) of patients and 51 (73%) were discharged as day cases. None re‐presented or had clinical complications within 24 hr. Nineteen (27%) were kept in hospital electively for observation. No preprocedural clinical or angiographic characteristics predicted successful or failed day‐case discharge. In selected patients who undergo uncomplicated PCI with stenting and device arterial closure, same‐day discharge appears safe and achievable in about three‐quarters of cases. Catheter Cardiovasc Interv 2003;60:18–24. © 2003 Wiley–Liss, Inc.
Insufficient tissue ablation by rotational atherectomy leads to worse long‐term results in comparison with balloon angioplasty alone for the treatment of diffuse in‐stent restenosis: Insights from the intravascular ultrasound substudy of the ARTIST randomized multicenter trial
Authors: Haager Philipp K. , Schiele François , Buettner Heinz J. , Garcia Eulogio , Bedossa Marc , Mudra Harald , Dietz Ulrich , di Mario Carlo , Reineke Thorsten , Horn Birger , Hoffmann Rainer , Radke Peter W. , Klues Heinrich G. , vom Dahl Juergen 
Published: August 2003

AbstractThe ARTIST trial demonstrated a worse outcome for patients with in‐stent restenosis (ISR) treated with rotational atherectomy (RA) and adjunctive balloon angioplasty (PTCA) as compared to PTCA alone. This intravascular ultrasound (IVUS) substudy compares effects of lumen enlargement and examines reasons for failure of RA in this setting. IVUS (n = 56) was performed after each interventional step and at follow‐up. Volumetric lumen gain measured 79 ± 68 mm3 after PTCA (13 ± 4 atm) as compared to 44 ± 26 mm3 after RA and adjunctive PTCA (7 ± 3 atm; P < 0.0001). RA itself enlarged lumen by only 19 ± 17 mm3 and stent volume was 47% smaller as compared to high‐pressure PTCA. Low‐pressure strategy after RA did not prevent tissue growth during follow‐up (19 ± 25 vs. 36 ± 38 mm3; RA vs. PTCA; P = 0.09). Consequently, net lumen gain after PTCA was 82% higher compared to RA (46 ± 54 vs. 25 ± 24 mm3; P = 0.09). Further stent expansion is the key mechanism to achieve luminal gain by PTCA of ISR. Neointimal ablation by RA has only minor effects. Low‐pressure PTCA does not prevent recurrent tissue growth and failed for treatment of ISR due to insufficient stent expansion. Catheter Cardiovasc Interv 2003;60:25–31. © 2003 Wiley–Liss, Inc.