bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction and application of a knowledge graph-based question answering system for Nanjing Yunjin digital resources
Authors: Xu Liang , Lu Lu , Liu Minglu 
Published: October 2023

Abstract
Nanjing Yunjin, one of China's traditional silk weaving techniques, is renowned for its unique local characteristics and exquisite craftsmanship, and was included in the Representative List of the Intangible Cultural Heritage of Humanity by UNESCO in 2009. However, with rapid development in weaving technology, ever-changing market demands, and shifting public aesthetics, Nanjing Yunjin, as an intangible cultural heritage, faces the challenge of survival and inheritance. Addressing this issue requires efficient storage, management, and utilization of Yunjin knowledge to enhance public understanding and recognition of Yunjin culture. In this study, we have constructed an intelligent question-answering system for Nanjing Yunjin digital resources based on knowledge graph, utilizing the Neo4j graph database for efficient organization, storage, and protection of Nanjing Yunjin knowledge, thereby revealing its profound cultural connotations. Furthermore, we adopted deep learning algorithms for natural language parsing. Specifically, we adopted BERT-based intent recognition technology to categorize user queries by intent, and we employed the BERT + BiGRU + CRF model for entity recognition. By comparing with BERT + BILSTM + CRF, BERT + CRF and BILSTM + CRF models, our model demonstrated superior performance in terms of precision, recall, and F1 score, substantiating the superiority and effectiveness of this model. Finally, based on the parsed results of the question, we constructed knowledge graph query statements, executed by the Cypher language, and the processed query results were fed back to the users in natural language. Through system implementation and testing, multiple indices including system response time, stability, load condition, accuracy, and scalability were evaluated. The experimental results indicated that the Nanjing Yunjin intelligent question-answering system, built on the knowledge graph, is able to efficiently and accurately generate answers to user’s natural language queries, greatly facilitating the retrieval and utilization of Yunjin knowledge. This not only reinforces the transmission, promotion, and application of Yunjin culture but also provides a paradigm for constructing other intangible cultural heritage question-answering systems based on knowledge graphs. This has substantial theoretical and practical significance for deeply exploring and uncovering the knowledge structure of human intangible heritage, promoting cultural inheritance and protection.
Tectonic significance of the 2021 Lamjung, Nepal, mid-crustal seismic cluster
Authors: Koirala Bharat Prasad , Laporte Marine , Bollinger Laurent , Batteux Daria , Letort Jean , Guilhem Trilla Aurélie , Wendling-Vazquez Nicolas , Bhattarai Mukunda , Subedi Shiba , Adhikari Lok Bijaya 
Published: October 2023

AbstractSince the Mw 7.9 Gorkha earthquake of April 25, 2015, the seismicity of central and western Nepalese Himalaya has been monitored by an increasing number of permanent seismic stations. These instruments contribute to the location of thousands of aftershocks that occur at the western margin of the segment of the Main Himalayan Thrust (MHT) that ruptured in 2015. They also help to constrain the location of seismic clusters that originated at the periphery of the fault ruptured by the Gorkha earthquake, which may indicate a migration of seismicity along the fault system. We report here a seismic crisis that followed the Lamjung earthquake, a moderate Mw 4.7 event (ML 5.8, MLv 5.3) that occurred on May 18, 2021, about 30 km west of the Gorkha earthquake epicenter at the down-dip end of the locked fault zone. The study of the hypocentral location of the mainshock and its first 117 aftershocks confirms mid-crustal depths and supports the activation of a 30–40° dipping fault plane, possibly associated with the rupture of the updip end of the MHT mid-crustal ramp. The cluster of aftershocks occurs near the upper decollement of the thrust system, probably in its hanging wall, and falls on the immediate northern margin of a region of the fault that has not been ruptured since the 1344 or 1505 CE earthquake. The spatio-temporal distribution of the first 117 aftershocks shows a typical decrease in the associated seismicity rate and possible migration of seismic activity. Since then, the local seismicity has returned to the pre-earthquake rate and careful monitoring has not revealed any large-scale migration of seismicity towards the locked fault segments.
Graphical Abstract
Report on the international workshop on seismic design and assessment for resilience, robustness and sustainability of slope engineering, 13–15 January 2023, Shanghai, China
Authors: Huang Yu , Mao Wuwei , Xiong Min , Wang Yian , Zhao Cuizhu , He Zhengying , Wang Fawu 
Published: October 2023

AbstractThe International Workshop on Seismic Design and Assessment for Resilience, Robustness and Sustainability of Slope Engineering was held on 13–15 January 2023 on line, focusing on the theme of “Seismic resilience of slope engineering and the concept of resilience-based seismic design (RBSD) for geological disaster prevention and control”. In this workshop, a number of keynote and invited lectures provided an international exchange platform for researchers, industrial engineers and students to share their research, engineering practice and exchange novel ideas on seismic resilience for slope engineering in a way of online. At the same time, during this workshop, technical committee of the ICGdR-TC1 also took this opportunity to hold a working meeting on cutting-edge and strategic issues, and released the Shanghai Declaration on slope engineering.
TrisOxine abiotic siderophores for technetium complexation: radiolabeling and biodistribution studies
Authors: Leenhardt Julien , Biguet Petit Jean Alexandre , Raes Florian , N’Guessan Emilien , Debiossat Marlène , André Clémence , Bacot Sandrine , Ahmadi Mitra , de Leiris Nicolas , Djaileb Loïc , Ghezzi Catherine , Brunet Marie-Dominique , Broisat Alexis , Perret Pascale , du Moulinet d’Hardemare Amaury 
Published: October 2023

Abstract
Background
Despite the development of positron emission tomography (PET), single photon emission computed tomography (SPECT) still accounts for around 80% of all examinations performed in nuclear medicine departments. The search for new radiotracers or chelating agents for Technetium-99m is therefore still ongoing. O-TRENSOX and O-TRENOX two synthetic siderophores would be good candidates for this purpose as they are hexadentate ligands based on the very versatile and efficient 8-hydroxyquinoline chelating subunit. First, the radiolabeling of O-TRENOX and O-TRENSOX with 99mTc was investigated. Different parameters such as the quantity of chelating agent, type of reducing agent, pH and temperature of the reaction mixture were adjusted in order to find the best radiolabeling conditions. Then an assessment of the partition coefficient by measuring the distribution of each radiosynthesized complex between octanol and phosphate-buffered saline was realized. The complex’s charge was evaluated on three different celluloses (neutral, negatively charged P81 and positively charged DE81), and finally in vivo studies with biodistribution and SPECT imaging of [99mTc]Tc-O-TRENOX and [99mTc]Tc-O-TRENSOX were performed.

Results
The radiolabeling studies showed a rapid and efficient complexation of 99mTc with both chelating agents. Using tin pyrophosphate as the reducing agent and a minimum of 100 nmol of ligand, we obtained the [99mTc]Tc-O-TRENOX complex with a radiochemical purity of more than 98% and the [99mTc]Tc-O-TRENSOX complex with one above 97% at room temperature within 5 min. [99mTc]Tc-O-TRENOX complex was lipophilic and neutral, leading to a hepatobiliary elimination in mice. On the contrary, the [99mTc]Tc-O-TRENSOX complex was found to be hydrophilic and negatively charged. This was confirmed by a predominantly renal elimination in mice.

Conclusions
These encouraging results allow us to consider the O-TRENOX/99mTc and O-TRENSOX/99mTc complexes as serious candidates for SPECT imaging chelators. This study should be continued by conjugating these tris-oxine ligands to peptides or antibodies and comparing them with the other bifunctional agents used with Tc.
Belt and road initiative and healthy silk road: an alternative path for Pacific island countries to participate in global public health governance
Authors: Mei Yujie 
Published: October 2023

AbstractPacific island countries (PICs) located in a region with relatively insufficient capacity to respond to public health emergencies, establishing reliable public health cooperation is conducive to maintaining security and stability. The belt and road initiative (BRI) launched by China attempts to provide a novel form of international cooperation and has supported multi-channel investment and construction. This article elucidates the history of public health cooperation between China and PICs, as well as the current situation of the BRI in the field of public health and emphasizes that there are numerous constraints in the public health cooperation between China and PICs. Given the profound impact of COVID-19 on diplomatic strategies, gradual cooperation in the field of public health may be the initial exploration of the BRI in the PICs, but it also means that the initiative must deal with challenges from geopolitical competition and cultural differences.
Schema matching based on energy domain pre-trained language model
Authors: Pan Zhiyu , Yang Muchen , Monti Antonello 
Published: October 2023

AbstractData integration in the energy sector, which refers to the process of combining and harmonizing data from multiple heterogeneous sources, is becoming increasingly difficult due to the growing volume of heterogeneous data. Schema matching plays a crucial role in this process by giving each representation a unique identity by matching raw energy data to a generic data model. This study uses an energy domain language model to automate schema matching, reducing manual effort in integrating heterogeneous data. We developed two energy domain language models, Energy BERT and Energy Sentence Bert, and trained them using an open-source scientific corpus. The comparison of the developed models with the baseline model using real-life energy domain data shows that Energy BERT and Energy Sentence Bert models significantly improve the accuracy of schema matching.
Finding individual strategies for storage units in electricity market models using deep reinforcement learning
Authors: Harder Nick , Weidlich Anke , Staudt Philipp 
Published: October 2023

AbstractModeling energy storage units realistically is challenging as their decision-making is not governed by a marginal cost pricing strategy but relies on expected electricity prices. Existing electricity market models often use centralized rule-based bidding or global optimization approaches, which may not accurately capture the competitive behavior of market participants. To address this issue, we present a novel method using multi-agent deep reinforcement learning to model individual strategies in electricity market models. We demonstrate the practical applicability of our approach using a detailed model of the German wholesale electricity market with a complete fleet of pumped hydro energy storage units represented as learning agents. We compare the results to widely used modeling approaches and demonstrate that the proposed method performs well and can accurately represent the competitive behavior of market participants. To understand the benefits of using reinforcement learning, we analyze overall profits, aggregated dispatch, and individual behavior of energy storage units. The proposed method can improve the accuracy and realism of electricity market modeling and help policymakers make informed decisions for future market designs and policies.
Cannabinoid hyperemesis syndrome presenting with ventricular bigeminy
Authors: Wong Jeffrey , Gill Muneet , Stead Thor , Huang Derrick , Ganti Latha 
Published: October 2023

AbstractThe is a case of a 28-year-old male presenting to an emergency department (ED) via emergency medical services (EMS) with a chief complaint of “gastritis.” He was noted to have bigeminy on the pre-arrival EMS electrocardiogram. He was ultimately diagnosed with cannabinoid hyperemesis syndrome (CHS). CHS is becoming an exceedingly common emergency department presentation due to the poorly regulated but widespread availability of cannabis products. The authors discuss a case of CHS and ventricular bigeminy.
Integrative bioinformatics analysis of miRNA and mRNA expression profiles identified some potential biomarkers for breast cancer
Authors: Rezaeijo Seyed Masoud , Rezaei Monireh , Poursheikhani Arash , Mohammadkhani Shima , Goharifar Naieme , Shayankia Ghazal , Heydarheydari Sahel , Saberi Alihossein , Taghizadeh Eskandar 
Published: October 2023

Abstract
Background
Breast cancer is a common cause of cancer death among women with a complex and heterogeneous picture in histological, molecular and clinical features. The aim of this study was to identify hub gene and their target microRNAs in related pathways for breast cancer.

Methods
We selected screening methods for differentially expressed mRNAs and miRNAs using expression profile data of breast cancer from the cancer genome atlas. Using some databases for annotation, the functional and pathway enrichment for differential expression genes was performed. We selected genes and miRNAs with differential expression pattern. Then we determined target genes for differential expression miRNAs (DEMIs) and intersection between them was selected as differentially expressed miRNA–target genes for breast cancer. In the next step, we constructed miRNA–mRNA regulatory network and protein–protein interaction (PPI) network for more information.

Results
Top 10 DEMIs were identified from miRNA profile. Then, we selected 354 genes as target gene for 10 DEMIs. The miRNA–mRNA and PPI network were constructed, and 10 hub genes and 5 miRNAs identified that some of them are new for breast cancer. Also, miRNA–target genes with differential expressions in this study were all mainly involved in signaling pathways and developmental process.

Conclusion
This study identified some candidate biomarkers for breast cancer that they have a potential role in pathways related to breast. These findings can be used for research, early diagnosis and therapeutic goals.
Prevalence of sleep disturbances and its relationship with mobile phone overuse among an Iranian sample of students: a necessity for attention
Authors: Elahi Fatemeh , Mojahedi Mahya , Salehiniya Hamid , Raeisoon Mohammad Reza 
Published: October 2023

Abstract
Background and objectives
Sleep disturbances are recognized as a potential core feature of some major psychiatric conditions, and overuse of mobile phones in recent years can leave potential negative effects on this central feature, which is especially important to assess among students. Our study aimed to investigate the prevalence of sleep disturbances and its relationship with mobile phone overuse among an Iranian sample of university students.

Methods
After 406 Iranian students from the Birjand University of Medical Sciences completed the demographic data, Mobile Phone Problematic Use Scale (MPPUS), and Pittsburgh Sleep Quality Index (PSQI) questionnaires, data were analyzed using independent t-test, analysis of variance, and Pearson correlation coefficient.

Results
74.4% of individuals had a moderate to severe problem with their subjective sleep quality, and 33.7% had moderate to severe problems with delay in falling asleep. Additionally, 44.1% of individuals experienced mild to moderate problems in sleep duration, and most of them (97.3%) severely suffered from inadequate sleep efficiency. In terms of sleep disorders, 78.8% of individuals reported a mild problem. Furthermore, most individuals (81.3%) have not used sleep-inducing medications to fall asleep, and in terms of daily dysfunction, 75.57% individuals had mild to moderate problems. Additionally, a significant positive correlation of 0.244 was observed between the score of sleep disturbances and mobile phone overuse (P < 0.05).

Conclusions
The prevalence of sleep disturbances was quite considerable, and there was a significant positive relationship between excessive mobile phone use and sleep disturbances among the target group.
Assessing readiness to implement long-acting injectable HIV antiretroviral therapy: provider and staff perspectives
Authors: Koester Kimberly A. , Colasanti Jonathan A. , McNulty Moira C. , Dance Kaylin , Erguera Xavier A. , Tsuzuki Manami Diaz , Johnson Mallory O. , Sauceda John A. , Montgomery Elizabeth , Schneider John , Christopoulos Katerina A. 
Published: October 2023

Abstract
Background
Long-acting injectable antiretroviral therapy (LAI-ART) represents the next innovation in HIV therapy. Pre-implementation research is needed to develop effective strategies to ensure equitable access to LAI-ART to individuals living with HIV.

Methods
We conducted focus group discussions (FGDs) with providers and staff affiliated with HIV clinics in San Francisco, Chicago, and Atlanta to understand barriers to and facilitators of LAI-ART implementation. Participants also completed a short survey about implementation intentions. FGDs were held via video conference, recorded, transcribed, and thematically analyzed using domains associated with the Consolidated Framework for Implementation Research (CFIR).

Results
Between September 2020 and April 2021, we led 10 FDGs with 49 participants, of whom ~60% were prescribing providers. Organizational readiness for implementing change was high, with 85% agreeing to being committed to figuring out how to implement LAI-ART. While responses were influenced by the unique inner and outer resources available in each setting, several common themes, including implementation mechanisms, dominated: (1) optimism and enthusiasm about LAI-ART was contingent on ensuring equitable access to LAI-ART; (2) LAI-ART shifts the primary responsibility of ART adherence from the patient to the clinic; and (3) existing clinic systems require strengthening to meet the needs of patients with adherence challenges. Current systems in all sites could support the use of LAI-ART in a limited number of stable patients. Scale-up and equitable use would be challenging or impossible without additional personnel. Participants outlined programmatic elements necessary to realize equitable access including centralized tracking of patients, capacity for in-depth, hands-on outreach, and mobile delivery of LAI-ART. Sites further specified unknown logistical impacts on implementation related to billing/payer source as well as shipping and drug storage.

Conclusions
Among these HIV care sites, clinic readiness to offer LAI-ART to a subset of patients is high. The main challenges to implementation include concerns about unequal access and a recognition that strengthening the clinic system is critical.
Dielectric materials development using bio-waste: a review
Authors: Zainol Norazwina , Mustafa Nurfarhana , Aziz Nor Hazwani , Azman Azahani Natasha , Abdul Karim Mohamad Shaiful 
Published: October 2023

AbstractThe increasing global demand for food due to population expansion has led to the intensification of the agricultural sector. However, this escalation in agricultural production has brought together undesirable consequences as more waste is produced, leading to growing environmental concerns as proper disposal of these wastes is necessary. Valorization of these bio-wastes into dielectric materials offers a promising solution to conventional, non-renewable, yet costly materials. Comprehensive documentation on the development of these wastes into dielectric materials is then necessary to understand their dielectric properties and how these materials behave with the treatments during the fabrication process. This review focuses on the state-of-the-art development of dielectric materials derived from bio-wastes and agricultural waste, which are beneficial for waste management and materials engineering applications. The elemental composition of the waste materials is also discussed in this review to understand its relationship with the dielectric constant. Moreover, the fabrication process for several waste materials into dielectric materials has been provided and compared. This review provides comprehensive information on green materials in the materials engineering industries and can assist in novel studies. It is foreseen that bio-wastes and agricultural wastes can be renewable, sustainable, and low-cost resources for deriving dielectric materials in light of their ease of accessibility.
Inflammatory Myofibroblastic Tumor With ROS1 Gene Fusions in Children and Young Adolescents
Authors: Schoot Reineke A. , Orbach Daniel , Minard Colin Veronique , Alaggio Rita , Di Carlo Daniela , Corradini Nadege , Mercolini Federico , Milano Giuseppe Maria , van Noesel Max M. , Rome Angelique , Dall’Igna Patrizia , Pajtler Kristian , Sparber-Sauer Monika , Ferrari Andrea , Casanova Michela 
Published: October 2023

PURPOSE Inflammatory myofibroblastic tumors (IMTs) are often driven by anaplastic lymphoma kinase fusions and less frequently by alternative fusions such as ROS1. We describe the clinical characteristics, treatment approach, and outcome for a series of young patients with IMTs and ROS1 alterations. METHODS This was a retrospective, international, multicenter study analyzing young patients (younger than 21 years) with ROS1-altered IMTs treated in 10 European referral centers between 2014 and 2022. Patients were included in the European pediatric Soft tissue sarcoma Study Group NRSTS-2005 protocol or registered in the Soft Tissue Sarcoma Registry. Primary surgery was recommended if a microscopic radical resection was feasible without mutilation. No standard systemic treatment protocol was available, but several medical options were recommended. RESULTS A total of 19 patients (median age 8.3 years) were included. Most patients had a biopsy at diagnosis (Intergroup Rhabdomyosarcoma Study [IRS] I; n = 2, IRS II; n = 1, IRS III biopsy; n = 11, IRS III resection; n = 3, IRS IV; n = 2). Twelve patients received neoadjuvant systemic therapy in first line (four received multiple treatments): high-dose steroids (n = 2), vinorelbine/vinblastine with methotrexate (n = 6), or ROS1 inhibitors (n = 8). After a median follow-up of 2.8 years (range, 0.2-13.4), seven patients developed an event. The 3-year event-free survival was 41% (95% CI, 11 to 71), and the 3-year overall survival was 100%. CONCLUSION Outcome for ROS1-altered IMTs appears excellent. A complete resection at diagnosis was often not feasible, and most patients needed neoadjuvant therapy. Patients who developed a tumor event could be cured with reinitiation of systemic therapy and/or surgery. This approach illustrates a switch in treatment philosophy moving from immediate, often mutilating, surgery to systemic (targeted) therapy as a bridge to more conservative surgery later in the treatment course.