bluuebunny/crossref_metadata_2025_split huggingface dataset:
α-Casozepine supplementation shows no effect on foals’ growth and cortisol levels before and after weaning
Authors: Wood Moriah K. , Mason Rocky M. , Burk Steffanie V. , Birmingham Sheri S. W. 
Published: January 2024

Abstract

OBJECTIVE
The goal of this study was to determine whether oral administration of α-casozepine (Zylkene) supplementation decreases the risk of disease in foals, as measured through salivary cortisol levels, temperature, clinical signs of disease, and body weight before and after weaning.

ANIMALS
20 Thoroughbred foals were observed over 10 weeks, beginning 14 days prior to the time of weaning.

METHODS
Experimental foals were randomly selected and given α-casozepine daily for 10 weeks, while the controls received a placebo with the same frequency as the experimental group. The average daily height and weight gain were calculated to examine the effects of α-casozepine before and after weaning. Salivary cortisol levels were also compared before versus after weaning.

RESULTS
There was no statistically significant difference in average daily height/weight gain or cortisol levels between the α-casozepine group and the control before and after weaning. However, the α-casozepine group had numerically less of a decline in height and growth compared to the control. This suggests that with further study Zylkene may decrease losses in foal growth rate.

CLINICAL RELEVANCE
The weaning process is one of the largest stressors in a young horse’s life. This abrupt process can contribute to an increased risk of disease and even morbidity. Other major stressors including separation from the mare, diet change, and new social groups can also lead to animal health and welfare concerns, as well as economic losses in weanling foals. However, further study is required to determine the benefits of α-casozepine on equine stress and health.
Dakwah Melalui Boneka (Studi pada Ustadzah Lulu Susanti)
Authors: Fitriani Nanda Elma , Amiliya Lina 
Published: January 2024

The purpose of this study was to find out the proselytizing strategy carried out by Ustadzah Lulu Susanti with puppet media. Modern society that tends to be pragmatic is also inseparable from the target of da'i. However, people tend to like a unique treat in proselytizing, namely using the medium of proselytizing. This research method uses qualitative with a descriptive approach. The primary data in this study was obtained by looking at the proselytizing carried out by Ustadzah Lulu Susanti in the media. Meanwhile, secondary data in this study were obtained from literature studies, journals, and other documents needed for the preparation of this article. This data analysis technique uses the Miles and Huberman Model with data reduction, data presentation, and conclusion drawing. The results of this study show that Dolls are one of the proselytizing media used by Ustadzah Lulu Susanti in delivering her syiar. This will certainly attract the attention of mad'u, especially among children. Thus, the treat of proselytizing becomes the satisfaction of mad'u who listens to the proselytizing. Ina is a doll name used in delivering proselytizing by Ustadzah Lulu which is able to attract a lot of attention from the public.
Upaya Masyarakat Pesisir Desa Tanggulsari dalam Berwirausaha Ditengah gempuran covid-19
Authors: Febryanti Ade 
Published: January 2024

Penelitian ini bertujuan untuk menganalisis pentingnya pengembangan masyarakat muslim dalam meningkatkan sumber daya alam di tempat tinggal daerah pesisir dalam berwirausaha sosial. Terlebih lagi saat ini ditengah pandemi covid-19 yang menimbulkan banyaknya pekerja yang kehilangan pekerjaanya. Hasil penelitian ini menunjukan bahwa mengembangkan hasil sumber daya alam di sekitar tempat tinggal dapat membantu masyarakat muslim memperbaiki perekonomiannya di tengah pandemi covid-19 juga masalah lainnnya. Sejumlah media terus melansir dan memberitakan berita tersebut kepada semua masyarakat, mengikuti arahan pemerintah untuk diam dirumah aja, karena tuntutan pekerjaan dan perekonomian sehari hari. Efek yang ditimbulkan ini mempersulit perekonomian masyarakat dan mengembangkan ide untuk mencari pekerjaan lainnya. Penelitian ini menunjukan bahwa pendapatan sumber daya alam untuk berkreasi memanfaatkan ikan sebagai usaha. Dengan pelatihan dan penyuluhan juga dampingan dapat menjadi industri rumahan dikelola secara individual atau kelompok. Selain itu penelitian ini menyimpulkan bahwa berwirausaha yang dijalankan masyarakat islam menjadi bagian dari tanggung jawab, dimana keseluruhan terdapat nilai nilai islam yang lebih dominan pada sosial kemanusiaan yang berorientasi pada keuntungan finansial.
Peningkatan Kompetensi Mahasiswa PMI: Pengalaman dari Praktik Lapangan di Dua Lembaga Mitra, Indonesia
Authors: Dianto Icol 
Published: January 2024

Penelitian ini bertujuan untuk mengelaborasi pengalaman praktik lapangan mahasiswa Program studi Pengembangan Masyarakat Islam Fakultas Dakwah dan Ilmu Komunikasi UIN Syekh Ali Hasan Ahmad Addary (PMI FDIK UIN Syahada) Padangsidimpuan. Pertanyaan mayor yang akan dijawab adalah bagaimana praktik lapangan berkontribusi terhadap peningkatan kompetensi mahasiswa? Metode yang digunakan adalah kualitatif eksploratif dan data primer dikumpulkan melalui wawancara terstruktur dengan menggunakan instrumen google form kepada 12 orang mahasiswa. Selain itu, wawancara dilakukan terhadap kepala laboratorium, dosen supervisor, dan ketua program studi. Hasil penelitian menemukan bahwa praktik lapangan mahasiswa PMI FDIK UIN Syahada Padangsidimpuan memiliki kontribusi yang sangat terbatas terhadap peningkatan kompetensi mahasiswa. Partisipasi mahasiswa mengikuti praktik lapangan optimal namun mereka meragukan kemampuan mereka, baik pengetahuan dan keterampilan yang relevan untuk praktik. Pada sisi lain, pengelolaan praktikum dan peran dosen supervisor perlu dirumuskan dengan baik. Rekomendasi diterbitkan untuk penyelenggara praktik lapangan, supervisor, lembaga mitra, dan mahasiswa. Keyword: Kompetensi, Praktik Lapangan, Supervisor, Laboratorium, Dakwah This study aims to elaborate on the field practice experience of students of the Islamic Community Development study program, Faculty of Da'wah and Communication Sciences, UIN Syekh Ali Hasan Ahmad Addary (PMI FDIK UIN Syahada) Padangsidimpuan. The primary question that will be answered is how field practices contribute to improving student competence. The method used was exploratory qualitative, and primary data were collected through structured interviews using Google Form instruments with 12 students. In addition, interviews were conducted with laboratory heads, supervisory lecturers, and heads of study programs. The study's results found that the field practice of PMI FDIK UIN Syahada Padangsidimpuan students needed more contributions to improving student competence. Student participation follows optimal field practice, but they need to be more confident in their abilities, knowledge, and skills relevant to practice. On the other hand, practicum management and the role of supervisory lecturers need to be well formulated. Recommendations are issued for field practice organizers, supervisors, partner institutions, and students. Keywords: Competence, Field Practice, Supervisor, Laboratory, Da'wah
Efek Pemberian Gel Ekstrak Etanol Daun Ekor Naga (Rhaphidophora pinnata (L.f) Schott) Sebagai Antiinflamasi Metode Carrageenan-Induced Air Pouch
Authors: Sani K Fathnur , Simamora Kristin , Rahman Havizur , Rahman Ave Olivia , Yuliawati Yuliawati 
Published: January 2024

The ethanol extract ekor naga leaves (Rhaphidophora pinnata (L.f) Schott) has been studied as an anti-inflammatory agent. This study aims to formulate a topical preparation of ekor naga leavesextract gel so that it can be a futher step from previous research as a product development effort. The research method used is experimental design. The treatment group was divided into five groups: positive control (Hydrocortisone), Formula 0 (Gel Base), Formula 1 (10% Extract Concentration), Formula 2 (15% Extract Concentration), and Formula 3 (20% Extract Concentration). The test animals used in each treatment group were 5 animals. The data obtained were analyzed using one way ANOVA with a 95% confidence level. The results showed that the more extracts, the better the anti-inflammatory effect. However, based on preparation evaluation data in previous studies regarding gel formulations, it was concluded that formula 2 was the best formula with an effect that was statistically almost the same as formula 3 and had good gel stability in the formulation.
Keywords: Ekor Naga Leaves, Gel, Inflammation, Air Pouch
Abstrak
Ekstrak etanol daun ekor naga (Rhaphidophora pinnata (L.f) Schott) telah diteliti memiliki efek sebagai agen antiinflamasi. Penenlitian ini bertujuan untuk memformulasi sediaan topikal gel ekstrak daun ekor naga sehingga dapat menjadi menjadi langkah lanjut dari penelitian sebelumnya sebagai upaya pengembangan produk. Metode penelitian yang digunakan adalah experimental design. Kelompok perlakuan dibagi menjadi lima kelompok yaitu: Kontrol positif (Hidrokortisone), Formula 0 (Basis Gel), Formula 1 (Konsentrasi Ekstrak 10%), Formula 2 (Konsentrasi Ekstrak 15%), dan Formula 3 (Konsentrasi Ekstrak 20%). Hewan uji yang digunakan masing-masing kelompok perlakuan 5 ekor. Data yang didapat dianalisis menggunakan ANOVA satu arah dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa semakin banyak ekstrak maka semakin baik efek antiinflamasinya. Namun berdasarkan data evaluasi sediaan pada penelitian sebelumnya tentang formulasi gel maka disimpulkan bahwa formula 2 merupakan formula terbaik dengan efek yang secara statistic hampir sama dengan formula 3 serta memiliki stabilitas gel yang baik dalam formulasi.
Kata Kunci: Daun Ekor Naga, Gel, Inflamasi, Air Pouch
Uji Reliabilitas the Functional Reach Test untuk Pengukuran Keseimbangan Statis pada Penderita Osteoarthritis Lutut
Authors: Komalasari Dwi Rosella , Amalia Hafiza 
Published: January 2024

Osteoarthritis (OA) is a chronic degenerative disease characterized damages the cartilage causing swelling, pain, muscle weakness, joint stiffness and reduced postural balance. The Functional Reach Test (FRT) is one of tests that can be used to measure static balance, unfortunately the reliability of FRT in Indonesia has not published as well including in patient with knee OA. The aim of this research is to determine test retest and inter rater reliability of FRT to measure static balance in patients with knee OA. This study used an observational study method with a methodological research approach. There were 58 participants who taken by purposive sampling. This study conducted in test retest and inter rater reliability of FRT. Test retest and inter rater reliability showed high internal consistency (?=0.82, ICC=0.69, p<0.0001, r=0.64) dan (?=0.84, ICC=0.72, p<0.0001, r=0.67). FRT is reliable in terms of test retest and inter rater reliability to measure static balance in patients with knee OA.
Keywords: Functional reach test, Knee Osteoarthritis, Realiability

Abstrak
Osteoarthritis (OA) adalah penyakit degeneratif kronis ditandai kerusakan tulang rawan pada sendi, menyebabkan bengkak, nyeri, penurunan kekuatan otot, kekakuan sendi serta keseinbangan tubuh yang mengakibatkan peningkatan resiko jatuh. Functional Reach Test (FRT) merupakan salah satu tes yang dapat digunakan untuk memeriksa keseimbangan statis, tetapi laporan tentang reliabilitas tes ini di Indonesia masih sangat terbatas terutama bagi pasien dengan OA lutut. Tujuan penelitian ini untuk mengetahui reliabilitas test retest dan inter rater reliability dengan pada FRT sebagai alat ukur untuk keseimbangan statis pada penderita osteoarthritis lutut. Penelitian ini menggunakan metode observational study dengan pendekatan methodological research. Terdapat 58 responden dalam penelitian ini yang diambil dengan purposive sampling. Test retest dan inter rater reliability FRT dievaluasi dalam penelitian ini. Hasil Test retest dan inter rater reliability FRT menunjukkan internal consistency tinggi (?=0.82, ICC=0.69, p<0.0001, r=0.64) dan (?=0.84, ICC=0.72, p<0.0001, r=0.67). FRT reliabel dalam hal test retes dan inter rater sebagai alat ukur keseimbangan statis pada penderita osteoarthritis lutut.
Kata Kunci: Functional reach test, Osteoarthritis lutut, Reliabilitas
Formulasi Serbuk Effervescent Limbah Tulang Ikan Bandeng (Chanos chanos) sebagai Supplement Kalsium Tulang
Authors: Wahid Hilmiati , Yustisi Andi Juaela , Prayitno Prayitno , Amir Aninditya Dwi Lestari 
Published: January 2024

Milkfish fish bone (Chanos chanos) is a fish with a high calcium consumption of 23.99%. This high level of calcium means that the waste of milkfish bones can be used as a bone supplement in the form of effervescent powder. to meet the intake of calcium supplements in maintaining health. This study aims to determine the physical and chemical stability of the effervescent powder from milkfish bone waste. The research method was calcium from milkfish bone meal analyzed using an Atomic Absorption Spectrophotometer and made in the form of effervescent powder with concentrations of 800 mg, 900 mg and 1000 mg. Examination of the preparations included organoleptic tests, pH tests, water content tests, flow rate tests, hedonic tests. The results for the organoleptic test did not change. The results of the solubility test, flow rate, pH test, water content test experienced an increase in value before and after the cycling test. The results of the F2 hedonic test favored the shape and color. It can be concluded that the calcium concentration of fish bone powder is 243121 mg/kg. Milkfish bone powder can be formulated in the form of effervescent powder as a bone calcium supplement that is physically and chemically stable
Kata Kunci: Waste of Milkfish Bones, Effervescent Powder, Calcium

Abstrak
Tulang ikan Bandeng (Chanos chanos) adalah ikan konsumsi berkalsium tinggi sebesar 23,99%. Tingginya kadar kalsium ini sehingga limbah tulang ikan bandeng dapat dimanfaatkan menjadi suplemen tulang dalam bentuk serbuk effervescent. untuk memenuhi asupan supplement kalsium dalam menjaga kesehatan. Penelitian ini bertujuan untuk mengetahui sediaan serbuk effervesent limbah tulang ikan bandeng yang stabil secara fisika dan kimia. Metode penelitian yaitu kalsium tepung tulang ikan bandeng dianalisis menggunakan Spektrofotometer Serapan Atom dan dibuat dalam bentuk sediaan serbuk effervescent dengan konsentrasi 800 mg, 900 mg dan 1000 mg. Pemeriksaan terhadap sediaan meliputi uji organoleptik, uji pH, uji kadar air, uji kecepatan alir, uji hedonik. Hasil penelitian untuk uji organoleptik tidak mengalami perubahan. Hasil uji waktu larut, kecepatan alir, uji pH, Uji Kadar air mengalami peningkatan nilai sebelum dan sesudah cycling test. Hasil uji hedonik F2 disukai dari bentuk dan warna. Dapat disimpulkan konsentrasi kalsium serbuk tulang ikan sebesar 243121 mg/kg. Serbuk tulang ikan bandeng dapat diformulasikan dalam bentuk sediaan serbuk effervescent sebagai supplement kalsium tulang yang stabil secara fisika dan kimia.
Kata Kunci: Limbah Tulang Ikan Bandeng, Serbuk Effervescent, Kalsium
Differential diagnosis of the causes of respiratory failure in children with achondroplasia. Clinical analysis
Authors: Балакирева Е.А. , Улезько А.А. , Николаенко И.В. , Плетенская С.Р. 
Published: January 2024

Проведен анализ трех клинических случаев детей с ахондроплазией в возрасте до 1 года с целью установления причин возникновения у них дыхательной недостаточности (ДН). Было установлено, что, несмотря на одну и ту же молекулярногенетически подтвержденную патологию – ахондроплазию, у троих детей первого года жизни триггеры возникновения ДН тяжелой степени, приведшей в двух случаях к смерти, а в одном – к вентиляционной зависимости, были различны. Наличие единого фонового механизма возникновения дыхательных расстройств (синдром сдавления каудальной группы черепномозговых нервов) предполагает разработку специального алгоритма ведения детей с ахондроплазией с первых дней жизни, учитывая высокую степень риска возникновения тяжелых дыхательных расстройств, провоцируемых различными пусковыми факторами и приводящих к необратимым последствиям.
Three clinical cases of children with achondroplasia before the age of 1 year were analysed to determine the causes of respiratory failure (DN). It was found that despite a single molecularly genetically confirmed pathology, achondroplasia, the triggers of severe DN, leading to death in two cases and to ventilatory dependence in one, were different in three children of the first year of life. The presence of a single background mechanism of respiratory distress (caudal CMN group compression syndrome) suggests the development of a special algorithm for the management of children with AHP from the first days of life, given the high risk of respiratory distress, provoked by various triggers, of severe severity, leading to irreversible consequences.
Optimization of standard protocols for subculturing mesenchymal stem cells from primary mouse bone marrow culture
Authors: Садовников Ф.А. 
Published: January 2024

Особый интерес научного сообщества привлекает терапевтический и иммуномодулирующий потенциал мультипотентных мезенхимальных стволовых клетках (ММСК) костного мозга. В связи с этим поиск эффективной методики выращивания клеток данного типа является актуальной задачей для экспериментальной медицины. Целью исследования стала оптимизация стандартных протоколов субкультивирования мышиных ММСК, получаемых из первичной культуры костного мозга. Материалы и методы. Оценивался выход клеток при пассировании трипсином или аккутазой с помощью различных методик спустя 14 дней культивирования суспензий костного мозга мышей линии ICR в посевных концентрациях первичной культуры: 10, 15-20 и 30 млн клеток на 25 см2 . Результаты. С помощью обработки в течение 15 мин 2 мл трипсина или 2 мл аккутазы удалось спассировать до 300 тыс адгезирующих и делящихся клеток при исходном посеве в 10 млн. По той же методике обработки удалось снять в 1,3–1,5 раза меньше клеток с посева в 15–20 млн за 15 мин и 30 млн клеток за 30 мин, а также культура значительно медленнее росла в 1-м пассаже Заключение. Посевная плотность первичной культуры костного мозга в 10 млн клеток на 25 см2 является оптимальной для получения адгезивной культуры мезенхимальных стволовых клеток мышей линии ICR. Субкультивирование с 2 мл трипсина или 2 мл аккутазы в течение 15 мин наиболее эффективно для получения первого пассажа.
The therapeutic and immunomodulatory potential of bone marrow multipotent mesenchymal stem cells (BMSCs) attracts special interest of the scientific community. In this regard, the search for an effective cell culture technique is an urgent task for experimental medicine. The aim of the study was to optimize the standard protocols for subculturing murine MMSCs obtained from primary bone marrow culture. Methods. The cell yield was evaluated by trypsin and accutase passaging using different methods after 14 days of culturing bone marrow suspensions of ICR line mice in seed concentrations of primary culture: 10, 15-20, 30 million cells per 25 cm2 . Results. With the help of treatment for 15 min with 2 ml of trypsin and 2 ml of accutase, it was possible to save up to 300 thousand adherent and dividing cells with an initial inoculation of 10 million. Using the same method, 30–35% fewer cells were removed from inoculation of treatment in 15–20 in 15 min and 30 million cells in 30 min. Conclusion. Seeding density of primary bone marrow culture of 10 million cells per 25 cm2 is optimal for obtaining an adherent culture of mesenchymal stem cells of mice of ICR line. Subculturing with 2 ml of trypsin and 2 ml of accutase for 15 min is most effective for obtaining the first passage.
Synthesis and characterization of LATP solid electrolyte by solution method
Authors: Turlybay G. , Nurgaziyeva E. , Issayeva D. , Mentbayeva A. , Bakenov Z. , Kalybekkyzy S. 
Published: January 2024

Recently, considerable attention has been paid to the study of solid electrolytes in lithium-ion batteries. Ion conductive ceramic material NASICON-type Li1+xAlxTi2-x(PO4)3 (LATP) is a promising solid electrolyte for lithium-ion batteries due to its stability in air. Here we report the results of LATP synthesis using the solution method. It has been found that the ionic conductivity of LATP is largely influenced by the preparation method. Pure LATP was obtained with the grain size of 100-700 nm. Measured ionic conductivity of the prepared LATP was in order of 10-5 S cm-1 at room temperature. Its typical particle size is between 100 and 700 nm, and its relative density is 89.5 percent.
Analysis of early postoperative outcomes after pancreatoduodenectomy with Braun entero-enteroanastomosis
Authors: Usenko O. Yu. , Skums A. V. , Halochka I. P. , Gulko O. M. , Symonov O. M. , Tsubera B. I. 
Published: January 2024

Objective. To evaluate early postoperative results after pancreatoduodenectomy with Brown entero–enteroanastomosis.
Materials and methods. Collected data of 162 patients who underwent pancreatoduodenectomy from 2015 to 2023. Group 1 was formed retrospectively and contained patients without Braun entero–enterostomy. Prospectivile formed Group 2 contained patients with Braun entero–enterostomy. The comparative analysis of 2 groups was performed.
Results. The overall incidence of delayed gastric emptying in both groups was 9.4%. At the same time, the frequency of delayed gastric emptying in the group 2 was significantly lower – 5.9% versus 15% in group 1, although the difference did not reach statistical significance (p=0.896).
Conclusion. Braun entero–enteroanastomosis during pancreatoduodenectomy reduced the frequency of delayed emptying, while not increasing the number of other complications.
Cultural Beliefs of Kejawen as Life Form of the Javanese in Islamic Theology Perspective
Authors: Suroyo  , Bima  
Published: January 2024

Kejawen is the belief of a multi-ethnic people on the Indonesian island of Java. Kejawen philosophy is based on Javanese thinkers' religious beliefs. This study aims to analyze the cultural beliefs of Kejawen from an Islamic Theology perspective with the objectives of this study are to determine the ritual of Kejawen in daily life from Islamic perspective and the materials used such as flowers and offerings in Kejawen which will be studied in Islamic perspective. This is an ethnographic study with the location of this study being in the Special Region of Yogyakarta and Solo. Documentation and observation are the instruments which are used for this study. The result found that Kejawen is an example of this fusion, with many Islamic elements. In Kejawen, God is known as Sang Hyang Taya, which is connected to the Islamic idea of Allah. Muslims believe that Allah is the one God and that no other gods exist. From an Islamic theological stance, Kejawen emphasizes the importance of inner spirituality, human experience, and the interconnection of all things in the cosmos. There are many connections between it and Islamic ideas, including as the concept of God and the power of prayer.