bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of psychological stress among the Russian population and its association with socio-demographic characteristics. Data from the ESSE-RF3 study
Authors: Drapkina O. M. , Gomanova L. I. , Balanova Yu. A. , Kutsenko V. A. , Imaeva A. E. , Kontsevaya A. V. , Maksimov S. A. , Muromtseva G. A. , Kotova M. B. , Karamnova N. S. , Shvabskaya O. B. , Evstifeeva S. E. , Kapustina A. V. , Litinskaya O. A. , Pokrovskaya M. S. , Kuzyakina S. O. , Soplenkova A. G. , Doludin Yu. V. , Efimova I. A. , Borisova A. L. , Yarovaya E. B. , Repkina T. V. , Gonoshilova T. O. , Kudryavtsev A. V. , Belova N. I. , Shagrov L. L. , Samotrueva V. A. , Yasenyavskaya A. L. , Chernysheva E. N. , Glukhovskaya S. V. , Levina I. A. , Shirshova E. A. , Dorzhieva E. B. , Urbanova E. Z. , Borovkova N. Yu. , Kurashin V. K. , Tokareva A. S. , Ragino Yu. I. , Simonova G. I. , Khudyakova A. D. , Nikulin V. N. , Aslyamov A. R. , Khokhlova G. V. , Solovyova A. V. , Rodionov A. A. , Kryachkova O. V. , Shamurova Yu. Yu. , Tantsyreva I. V. , Baryshnikova I. N. , Ataev M. G. , Radjabov M. O. , Isakhanova M. M. , Umetov M. A. , Elgarova L. V, , Khakuasheva I. A. , Yamashkina E. I. , Esina M. V. , Kunyaeva T. A. , Nikitina A. M. , Savvina N. V. , Spiridonova Yu. E. , Naumova E. A. , Keskinov A. A. , Kashtanova D. A. , Yudin V. S. , Yudin S. M. , Shalnova S. A. 
Published: February 2024

Aim. To assess the prevalence of psychological stress (PS) using the Perceived Stress Scale-10 (PSS-10) in various Russian regions and to analyze PS associations with socio-demographic characteristics and behavioral risk factors and some non-communicable diseases (NCDs).Material and methods. We studied representative samples of the population aged 35-74 years in the Russian regions, examined as part of the Epidemiology of Cardiovascular Diseases in Regions of Russian Federation-3 (ESSE-RF3) study. The subjects were interviewed using a questionnaire containing a section on the psychological stress — PSS-10. For men, PS levels are ranked as follows: "Low" — 0-11, "Medium" — 12-17, "High" — 18-40. For women, PS levels are ranked as follows: "Low" — 0-13, "Medium" — 14-19, "High" — 20-40. Statistical analysis was carried out using the open-source R 3.6.1 environment.Results. The average PS level was 12,0±7,3 (men: 10,7±7,0; women: 13,1±7,4). Every fifth person (20,3%) in the Russian population has a high PS level, with higher PS rates among women compared to men (high PS level — 21,6 vs 18,9%, respectively). A high PS level was associated with the income level (average or low), no marriage, unemployment, low level of physical activity, depression, anxiety, NCDs (type 2 diabetes, myocardial infarction, stroke), additionally for women — hypertension.Conclusion. The Russian population is characterized by a high PS prevalence, while PS rates are higher among women, which must be taken into account when predicting the NCD risks.
Optimum design of an acetylated starch plant from Manihot esculenta Crantz, variety INIVIT-Y-93-4
Authors: Acosta-Solares Amanda , Pérez-Navarro Omar , Sánchez-Cabrera Ernesto , Pérez-Díaz Jorge Luis 
Published: February 2024

Considering the applicability and added value of acetylated starches, it is necessary to find technological variants to obtain them with favorable technical-economic results and energetic and environmental compatibility. The objective of the work is to optimize economic and dynamic indicators of profitability of acetylated starch production, by considering as optimization criteria the productive capacity, the degree of substitution and the temperature of the drying air, establishing the design of the installation in optimal conditions. Technologies adopted from the mechanized native starch processes were selected, and the design and development of the slurry heating, acetylation, and pneumatic drying stages were proposed. A composite central experimental design was generated for profit (P), net present value (NPV), and internal rate of return (IRR), and the quadratic models obtained through the Response Surface Methodology were optimized. For the evaluation of the indicators, the economic indexes of the process were determined, after technological selection, material and energy balances, and technological design. The optimum operating parameters are achieved at a production capacity of 12.57 tcassava/d, degree of substitution of 0.505 and 124.98 °C in the air supply to the pneumatic dryer. Under these conditions, the production of acetylated starch requires larger volume acetylators than for acetylated gelatinized starch process, but the technological requirements of gelatinized pulp are eliminated, achieving remarkable energy efficiency with pneumatic drying.
Aplicabilidad de estrategia metodológica en el programa orientación vocacional de la educación media-técnica. Venezuela
Authors: Cueto Ruth 
Published: February 2024

Se presenta el avance de un estudio cualitativo de alcance exploratorio en el cual se formuló como objetivo estimar la aplicabilidad de una estrategia metodológica para el Programa Área de Formación Orientación Vocacional en la Educación Media-Técnica de Venezuela, que permita atender a estudiantes de primero a quinto año, con la asistencia por lo menos de un orientador en cada institución educativa. Se propone administrar una estructura modular, rotativa, interinstitucional y multidisciplinaria. Los datos se obtuvieron mediante la utilización de tres recursos de análisis, la revisión de documentos legales e institucionales, la comparación con un antecedente análogo realizado en la Facultad de Medicina de la Universidad del Zulia durante el periodo 1997-2008 y la valoración de un ejercicio de simulación. Entre las conclusiones se destacan que para su gestión se requiere, por un lado, fortalecer entre la comunidad educativa condiciones como la disciplina, la concentración, la paciencia y la preocupación por los objetivos deseados y por otro, la administración de una prueba piloto durante el año escolar 2023-2024.
CORRELATION OF FAMILY SUPPORT AND FAMILY RESILIENCE WITH DHF PREVENTION BEHAVIOR IN OLDER ADULTS
Authors: Sumarsih Gusti , Freska Windy , Claudia Lara 
Published: February 2024

Background: The elderly are a vulnerable age group for Dengue Haemorrhagic Fever (DHF) with a high risk of death. Families must carry out their roles in efforts to prevent DHF in older adults. Purpose: This study aims to identify the correlation between family support and resilience with DHF prevention behavior. Methods: This study used a correlational design to detect a relationship between family support and resilience variables and DHF prevention behavior by older adults. The research location was at the Andalas Health Center in Padang, with 96 randomly recruited from seven elderly Integrated Public Health Centers. The instrument consisted of three closed-question questionnaires. Family support is identified through informational, reward, instrumental, and emotional indicators, while family resilience includes relationship communication, positive framing, and external resources. Data were analyzed using the Spearman Rho test. Results: Most respondents were older adults (73.96%) aged 60-65 (68.75%). The correlation test between family support and family resilience with DHF prevention behavior has a significant relationship (0.00). Testing the correlation partially on each indicator shows the highest level of correlation on the instrumental indicator (0.83). The correlation between family support and resilience was highest on emotional and communication-relationship indicators (0.71). Conclusion: Family support and resilience are correlated with DHF prevention behavior by the elderly. Emotional support from the family through communication appropriate to the older adults' age phase is needed to prevent DHF.
A dual-circuit causal model of depression in humans
Authors: Frandsen Summer , Glover Cory , Cash Robin , Blumberger Daniel , Choi Ki Sueng , Dougherty Darin , Downar Jonathan , Fitzgerald Paul , George Mark , Horn Andreas , Grospietsch Friederike , Johnson Kevin , Kühn Andrea , Mayberg Helen , Pascual-Leone Alvaro , Riva-Posse Patricio , Rouhl Rob , Schaper Frederic , Taylor Stephan , Temel Yasin , Vila-Rodriguez Fidel , Zalesky Andrew , Grafman Jordan , Siddiqi Shan 
Published: February 2024

Abstract
Therapeutic brain stimulation targets are typically designed to treat specific psychiatric or neurological symptoms.1–4 This approach presents a dilemma when treating patients with comorbidities, atypical symptom profiles, or overlapping symptoms. Identifying targets that modulate groups of behavioral or cognitive symptoms across diagnoses may provide alternative treatment options and outcomes. Here, we use causal brain mapping and clustering methods to identify two distinct brain networks, based on common patterns of connectivity to lesions that selectively modify behaviors and symptoms. Due to the behavioral items in each cluster, we hypothesize that these networks are related to positive and negative affect, respectively. Across ten different datasets of patients receiving transcranial magnetic stimulation (TMS) or deep brain stimulation (DBS),1,5,6 stimulation site connectivity to each of our two brain networks independently predicted improvement in depressive symptoms. Thus, we defined two networks which are independently and causally involved in depression symptoms.
Observation of the non-Hermitian skin effect and Fermi skin on a digital quantum computer
Authors: Lee Ching Hua , Shen Ruizhe , Chen Tianqi , Yang Bo 
Published: February 2024

Abstract

Non-Hermitian physics has attracted considerable attention in the recent years, in particular the non-Hermitian skin effect (NHSE) for its extreme sensitivity and non-locality. While the NHSE has been physically observed in various classical metamaterials and even ultracold atomic arrays, its highly-nontrivial implications in many-body dynamics have never been experimentally investigated. In this work, we report the first observation of the NHSE on a universal quantum processor, as well as its characteristic but elusive Fermi skin from many-fermion statistics. To implement NHSE dynamics on a quantum computer, the effective time-evolution circuit not only needs to be non-reciprocal and non-unitary, but must also be scaled up to a sufficient number of lattice qubits to achieve spatial non-locality. We show how such a non-unitary operation can be systematically realized by post-selecting multiple ancilla qubits, as demonstrated through two paradigmatic non-reciprocal models on a noisy IBM quantum processor, with clear signatures of asymmetric spatial propagation and many-body Fermi skin accumulation. To minimize errors from inevitable device noise, time evolution is performed using a trainable optimized quantum circuit produced with variational quantum algorithms. Our study represents a critical milestone in the quantum simulation of non-Hermitian lattice phenomena on present-day quantum computers, and can be readily generalized to more sophisticated many-body models with the remarkable programmability of quantum computers.
ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity
Authors: Fulton Stephanie , Lau David , Tobin Stephanie , Pribiag Horia , Nakajima Shingo , Fisette Alexandre , Matthys Dominique , Flores Anna Kristyna Franco , Peyot Marie-Line , Madiraju S.R. Murthy , Stellwagen David , Alquier Thierry , Prentki Marc 
Published: February 2024

Abstract

α/β-hydrolase domain 6 (ABHD6) is a lipase linked to physiological functions affecting metabolism and body weight. Brain ABHD6 degrades 2-arachidonoylglycerol and thereby modulates cannabinoid receptor signaling. However, it’s functional role within mesoaccumbens circuitry that is critical for motivated behavior and known to be significantly modulated by endocannabinoids remained unknown. Using three viral approaches, we show that control of the nucleus accumbens by neuronal ABHD6 is a key determinant of body weight and reward-relevant behavior. Contrary to expected outcomes associated with increasing endocannabinoid tone, ABHD6 loss of function in the nucleus accumbens, but not the ventral tegmental area, inhibited food reward and completely prevented diet-induced obesity and associated physical inactivity without affecting anxiodepressive behavior. These effects are explained by attenuated inhibitory synaptic transmission onto medium spiny neurons. ABHD6 deletion in nucleus accumbens neurons and dopamine ventral tegmental area neurons produced contrasting effects on food-directed behavior. Together, these results reveal functional specificity of pre- and post-synaptic mesoaccumbens neuronal ABHD6 to differentially control energy metabolism and propose ABHD6 inhibition as a potential anti-obesity tool.
Time to recovery of asphyxiated neonates and it’s predictors among newborns admitted to neonatal intensive care unit at Debre Berhan Comprehensive Specialized Hospital, Ethiopia
Authors: Girma Sisay , Tesfahun Esubalew , Mamo Tadesse , Abebe Zenebe 
Published: February 2024

Abstract

Background Even though there have been inquiries into the survival rates of asphyxiated neonates in Africa, there is scarce data concerning the recovery duration for asphyxiated newborns in developing nations and the factors affecting this process. Consequently, the objective of this study is to ascertain the time it takes for asphyxiated neonates to recover and identify its predictors. Methods Conducting a retrospective follow-up investigation, the study took place at Debre Berhan Comprehensive Specialized Hospital from January 1st, 2020 to December 31st 2022, involving a sample size of 330. The analysis included the computation of the Kaplan-Meier survival curve, the log-rank test, and the median time. Additionally, a multivariable Cox proportional hazard regression model was employed to determine the survival status. Results in this study, among the 330 participants (100%), a total of 270(81.8%) successfully survived throughout the entire cohort. Predictors are independent of each other, affecting the time to recovery and survival of asphyxiated neonates, encompassed prolonged labor (AHR: 0.42 ,95%CI:0.21–0.81), normal birth weight (AHR:2.21 ,95% CI: 1.30–3.70),non-altered consciousness (AHR:2.52 ,CI:1.50–4.24) ,non-depressed moro reflex of the newborn (AHR:2.40 ,95%CI: 1.03–5.61), stage I HIE (AHR: 5.11 ,95% CI: 1.98–13.19) ,and direct oxygen administration via the nose (AHR: 4.18 ,95% CI: 2.21–7.89). Conclusion The duration for recovery seems to be slightly prolonged in comparison to other research findings. This underscores the significance of vigilant monitoring, early preventive interventions, and swift actions to avert the progression of infants to the most severe stage of HIE.
Analysis on the impact of table tennis elective courses on college students' physical fitness and competitive skills
Authors: Chen Baibing , Xie Dongfang , Xiao Xiangyu , Cai Hangchuan , Hu Yongqing 
Published: February 2024

Abstract
Table tennis is one of the sports that are particularly popular among university students. Given the significant differences in students' athletic abilities and physical functions, how to improve their competitive level and physical health has becoming noticeable problems via table tennis. To solve problems such as passive student participation, insufficient training, an imbalance between in-class and extracurricular activities, and low levels of physical fitness, this study utilized a 3 + 1 digital class to activate student interesting and a combined teaching and competition platform to enhance table tennis skills, which was explored the impact of integrating in-class and extracurricular table tennis elective courses on improving students' physical fitness and competitive levels. The results indicate that students table tennis competitive abilities and physical health have significantly improved after the reform, which is provides references for enhancing the quality of table tennis instruction, improving university students’ physical health, and promoting the universal applicability of table tennis teaching reforms in higher education institutions.
Evaluation of early joint damage via ultrasound imaging in patients with psoriasis: a single center retrospective study
Authors: Qi Fei , Yao Amin , Yang Xutong , He Yanling 
Published: February 2024

Abstract

Background:
Psoriatic joint damage is occult and often asymptomatic, however, it can cause irreversible permanent joint damage in the late stage and affect the quality of life of patients. It is important to identify potential joint damage early and slow the progression of the disease.
Objective: This study aimed to explore the risk factors for early joint damage in patients with psoriasis vulgaris using color Doppler ultrasonography.
Methods：
Hand joint Doppler ultrasound data of 100 patients with skin psoriasis in the outpatient department of Dermatology of Beijing Chaoyang Hospital from July 2017 to December 2021 were reviewed. We also reviewed the clinical characteristics between the two groups of patients, using statistical methods to analyze the differences in the risk factors between patients with and without symptomatic joint damage and those without joint damage under the early ultrasonic detection of psoriasis.
Results：
In this study, 100 patients with psoriasis vulgaris were examined using grayscale Doppler ultrasonography. 65 cases (65%) were male, and 39 (39.0%) had joint damage. Two out of 39 patients had psoriatic arthritis in the following 3 years. After multivariate logistic regression analysis, it was found that the independent risk factors for joint damage in patients with psoriasis vulgaris were age (OR: 1.659, 95% CI: 1.217-2.261, P = 0.001), total cholesterol or 1.625, 95% CI: 1.053-2.292, P = 0.006), age at first onset (OR: 1.329, 95% CI: 1.049-1.683, P = 0.019), course of disease ( 1.615, 95% CI: 1.113-1.799, P = 0.005), nail accumulation (OR: 4.137, 95% CI: 1.755-9.752, P = 0.001), smoking (OR: 10.337, 95% CI: 4.109-26.009, P = 0.000), and diabetes (OR:8.575, 95%CI:1.868-39.362, P=0.006).
Conclusion:
Patients with psoriasis vulgaris and a history of nail damage, smoking, drinking, coronary heart disease, and hyperlipidemia were more likely to have early joint damage. Patients with psoriasis vulgaris with age, elevated total cholesterol, early onset age, nail accumulation, smoking history, and diabetes history should be removed early using joint Doppler ultrasound to exclude early joint damage.
Aging and rare diseases: from epidemiology to a call to action
Authors: Mazzucato Monica , Fanton Giulia , Vianello Andrea , Minichiello Cinzia , Pozza Laura Visonà Dalla , Toto Ema , Ceolin Chiara , Coin Alessandra , Sergi Giuseppe , Facchin Paola 
Published: February 2024

Abstract
Background
The number of older people living with a rare disease (RD) is increasing worldwide due to the population aging and scientific progress. This phenomenon poses several challenges for both patients and healthcare providers, who need to be aware of the peculiarities of this twice-as-frail population.
Methods
In the present study, we used data from the Veneto region rare disease registry (VRRDR) to investigate the epidemiology of older people living with a RD in the Veneto region of Italy. We report the number of patients diagnosed in old age and the number of those transited from adulthood into old age, estimating the prevalence of older RD patients as of 31 December 2022. Finally, we analyzed the composition of their therapeutic plans.
Results
During the study period, 8,975 patients received an RD diagnosis after 65 years of age, while 4,214 diagnosed in their childhood or adulthood experienced the transition to old age. On 31 December 2022, there were 9,508 patients aged 65 years or more residing in the study area, 20.8% of all Veneto’s RD patients. The most common groups of RDs in elderly patients were systemic or rheumatologic, neurologic, and skin diseases, affecting 27%, 25%, and 9% of the monitored geriatric population, respectively. Among prevalent cases, 1,519 patients older than 65 years had a therapeutic plan related to their rare condition. Specifically, the most prescribed drugs were those affecting the nervous system (27.8%), the alimentary tract and metabolism (12.8%), and antineoplastic and immunomodulating agents (11.6%).
Conclusions
As older patients represent a growing number in the RD population, geriatricians and general practitioners should be involved in RD care and training programs. Further studies are needed to determine the unmet care needs of older RD patients in order to design health policies able to address the peculiar challenges posed by this group of patients emerging within the RD population.
Do “oversized” Hall Technique crowns affect intra-arch dimensions? A split-mouth quasi experimental pilot study
Authors: Hussein Iyad , AlRamzi Batoul , Halabi Manal Al , Kowash Mawlood , Salami Anas , Hassan Amar , Ghoneima Ahmed 
Published: February 2024

Abstract

Background: The Hall-Technique preformed-metal-crowns (HT-PMCs) are allegedly oversized, temporarily altering inter-arch relationships.Intra-archdimensions/Leeway-space (LWS) HT effects are unknown.Aim:To study single HT-PMC intra-arch effects and treated tooth dimensional changes.Materials and Methods:Split-mouth quasi-experimental pilot study. Intra oral scans (iTeroII®) were taken pre-orthodontic separator placement (scan1), immediately post single HT-PMC (scan2) and 1-month later (scan3) in 13 children. Control/ study quadrants’ lengths (“arcs”), and HT-PMC/control tooth dimensions [mesiodistal (MD), buccopalatal/lingual (BP/L), diagonal (Diag1/Diag2)] were recorded inmm(OrthoCad®software). Paired t-test, repeated ANOVApost-hocanalysis statistics (p<0.05).Results:Compared to scan1,the mean study-arc increased by 0.69mm (±0.54) [(n=13, t-test, p<0.001) at scan2,while at scan3,it increased by 0.787mm (±0.34) [(n=8, Repeated ANOVA, p=0.008)]. The HT-PMC treated tooth mean dimensions increased at scan2by 0.86mm (MD), 0.8mm (BP/L), 0.5mm (Diag1) and 0.69mm (Diag2) (t-test, p<0.001) with similar observations at scan3. There were no significant changes in the control arc nor the control tooth measurements.Conclusion:HT-PMCs increased the intra-arch quadrant length by approximately >1mm. The HT-PMC treated tooth was marginally oversized. This may potentially increase the LWS and contribute to impaction of unerupted first permanent molars, if more than one PMC was used in the quadrant/arch.