bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rotator cuff muscle fibrosis can be assessed using ultrashort echo time magnetization transfer MRI with fat suppression
Authors: Chang Eric Y. , Suprana Arya , Tang Qingbo , Cheng Xin , Fu Eddie , Orozco Elisabeth , Jerban Saeed , Shah Sameer B. , Du Jiang , Ma Yajun 
Published: October 2023

AbstractMuscle degeneration following rotator cuff tendon tearing is characterized by fatty infiltration and fibrosis. While tools exist for the characterization of fat, the ability to noninvasively assess muscle fibrosis is limited. The purpose of this study was to evaluate the capability of quantitative ultrashort echo time T1 (UTE‐T1) and UTE magnetization transfer (UTE‐MT) mapping with and without fat suppression (FS) for the differentiation of injured and control rotator cuff muscles and for the detection of fibrosis. A rat model of chronic massive rotator cuff tearing (n = 12) was used with tenotomy of the right supraspinatus and infraspinatus tendons and silicone implants to prevent healing. Imaging was performed on a 3‐T scanner, and UTE‐T1 mapping with and without FS and UTE‐MT with and without FS for macromolecular fraction (MMF) mapping was performed. At 20 weeks postinjury, T1 and MMF were measured in the supraspinatus and infraspinatus muscles of the injured and contralateral, internal control sides. Histology was performed and connective tissue fraction (CTF) was measured, defined as the area of collagen‐rich extracellular matrix divided by the total muscle area. Paired t‐tests and correlation analyses were performed. Significant differences between injured and control sides were found for CTF in the supraspinatus (mean ± SD, 14.5% ± 3.9% vs. 11.3% ± 3.7%, p = 0.01) and infraspinatus (17.0% ± 5.4% vs. 12.5% ± 4.6%, p < 0.01) muscles, as well as for MMF using UTE‐MT FS in the supraspinatus (9.7% ± 0.3% vs. 9.5% ± 0.2%, p = 0.04) and infraspinatus (10.9% ± 0.8% vs. 10.1% ± 0.5%, p < 0.01) muscles. No significant differences between sides were evident for T1 without or with FS or for MMF using UTE‐MT. Only MMF using UTE‐MT FS was significantly correlated with CTF for both supraspinatus (r = 0.46, p = 0.03) and infraspinatus (r = 0.51, p = 0.01) muscles. Fibrosis occurs in rotator cuff muscle degeneration, and the UTE‐MT FS technique may be helpful to evaluate the fibrosis component, independent from the fatty infiltration process.
Modified settlement‐stability‐optimization method for numerical foundation design of tower cranes
Authors: Müllner Herbert W. , Koza Martin 
Published: October 2023

AbstractThe static design of foundations for tower cranes is mostly based on calculations of structural safety like tilting, sliding and groundbreaking. Settlement calculations for evaluating the inclination of the crane, which is restricted by the suppliers of tower cranes , are essential for safe and economic foundation solutions, too. Based on the experience of more than 280 tower crane positions throughout Austria and Germany the method of Müllner & Meister has been extended satisfying the normative and crane specifically requirements and represents an obligation of one of the biggest building contractors in Europe in the sense of today's resource‐saving management.
Front Cover Image
Authors: Wu Sheng‐Yen , Tang Huatao , Zhang Chen , Tang Fanxi , Lin Jihang , Wang Yuxin , Chen Lihong , Hou Youming 
Published: October 2023

The cover image is based on the Research Article Potential of entomopathogenic nematode‐infected insect cadavers for the biocontrol of the red imported fire ant Solenopsis invicta by Sheng‐Yen Wu et al., https://doi.org/10.1002/ps.7637.image
‘Ask a hundred people, you get a hundred definitions’: A comparison of lay and expert understanding of stress and its associations with health
Authors: Wezyk Agata B. , Arden‐Close Emily , Turner‐Cobb Julie M. 
Published: October 2023

AbstractThe understanding an individual holds about stress can influence their appraisal of it and have implications for subsequent health, yet knowledge of such understanding is scarce. This study explored discrepancies between lay and expert understanding of stress and links made between stress and health. Twenty‐six lay members of the local community aged 18–62 years, and seven expert stress researchers, participated in individual semi‐structured interviews. Thematic analysis of the two datasets was conducted separately, then findings compared to identify similarities and differences between lay and scientific understanding. Whilst many similarities were identified, we found three important discrepancies: (i) Lay participants demonstrated a strong awareness of the indirect effects of stress on health via health behaviours; (ii) compared to experts, lay participants showed less awareness of a direct path between stress and physical health; (iii) lay participants showed less understanding of social determinants of stress and collective measures for stress management that went beyond individual responsibility. Discrepancies identified serve to highlight potential misunderstandings in lay conceptualisation of stress and its links with health. These findings have potential to facilitate the work of practitioners who serve as intermediaries to translate scientific knowledge into therapeutic benefit, through improved awareness and communication surrounding stress understanding.
Estimation of ductility of concrete columns under horizontal seismic load
Authors: Chang Wei , Hao Meijing , Zheng Wenzhong 
Published: October 2023

AbstractThe ductility of concrete columns, which determined the deformability of concrete columns, was an important parameter in evaluating the safety of framework structures under horizontal seismic loads. In this paper, 231‐group test data for evaluating the ductility of concrete columns under seismic loads were collected to establish a reliable database. The effects of investigated parameters including the compressive strength of concrete, the lateral confinement of stirrups, the ratio and yield strength of longitudinal reinforcements, axial compression ratio, shear span ratio, and the ratio between gross area and confined concrete area on the ductility of concrete columns were analyzed. The accuracy of theoretical models for evaluating the ductility of confined concrete relied on the prediction performance for the plastic hinge length of the concrete column. The existing models for the plastic hinge length of concrete columns underestimated the test results, which should be re‐evaluated. The prediction models were developed to evaluate the ductility of concrete columns based on the parametric analysis, which had high prediction performance. In addition, the design ductility limited value of concrete columns under horizontal seismic loads was obtained.
Other People’s Ideas: An Introduction to Using Social Theory in Higher Education
Authors: Low Remy Y. S. , Egan Suzanne 
Published: October 2023

AbstractIn this introductory chapter, we explore our transformative early encounters with social theories and discuss what social theory is, the different ways it can be used in the context of higher education, and its limitations. The chapter explains how the authors in this book put social theories to work to think through issues that are emerging as key social and political concerns in a higher education context. We provide a brief overview of each chapter and present the social theorists that each author engages with, including Indigenous Australian scholar Aileen Moreton-Robinson, Māori academic Linda Tuhiwai Smith, Belgian political theorist Chantal Mouffe, Slovenian philosopher Slavoj Žižek, British sociologist Nikolas Rose and Lebanese history of medicine scholar Joelle M Abi-Rached, and the Australian sociological theorist Raewyn Connell. Along the way, we offer some advice on how to (and how not to) think with theory.
Understanding Higher Education Enrolment Through Michel Foucault’s Biopolitics
Authors: Xu Ren-Hao 
Published: October 2023

AbstractHigher education enrolment is and has historically been a demographic-political problem around the world over the last four decades. This can be reflected in many governments’ attempts to widen university access to make their national populations more skilled and productive. Most extant research on this matter investigates the effectiveness of such enrolment policies in addressing the problems outlined by governments. However, I noticed that the enrolment problems were not simply about achieving greater student participation; rather, the enrolment ‘problem’ is tied up with the formation of modern statehood and the subjectivities of national populations. In this chapter, I suggest drawing upon Michel Foucault’s work on biopolitics to understand how higher education enrolment has become an object linked to population characteristics and political legitimacy. I use the historical higher education enrolment concerns of Australia and OECD as case studies to explore how specific ideas conceive unique ‘problems’. More importantly, I point to how we can reimagine the landscape of higher education centred on the participation of students from different backgrounds through the perspective of biopolitics.
Wrestling with Monsters: Critique, Climate Change, and Comets
Authors: Norman Pat 
Published: October 2023

AbstractWe live, as the Chinese saying supposedly goes, in interesting times. Žižek (2012) argues that our times constitute a state of permanent crisis. This sense of crisis is felt across material domains through climate change or geopolitics, to policy settings that respond to ‘crises’ in our bureaucracies. How are we to respond to such a state? In this chapter, I discuss Žižek’s call not to act, but to think. Žižek’s project uses psychoanalytic ideology critique to pose questions about the way people understand the ‘problems of society’. He uses the metaphors of masks and fantasy to unpack the way particular ‘truths’ are symbolic representations that act to construct hegemonic ideologies that define the world. The intellectual work of the academy—that which ‘has no practical use’ (Žižek, 2012. Counterpoints, 422, 32–44)—involves the interrogation and critique of these masks: to explore how the ways we perceive a problem can themselves be part of the problem. Faced with these complex, mediated rationalities, Žižek argues that there is often a push to act quickly, often in ways that do not create solutions. The challenge is to find ways to re-articulate the problems of our world in ways that transform our understanding and therefore the terrain of possibility. This chapter engages with this challenge through the lens of climate change and the school strike movement.
Still Wrestling with Monsters: A Response to Pat Norman
Authors: Grice Christine 
Published: October 2023

AbstractŽižek’s (2012) provocative revelation warns that we are ‘living in the time of monsters’, as western cultures enter ‘a new dark ages’ of permanent capitalist crisis. Žižek is referring to ideological masks that impact education and educational researchers: the greed of capitalism, twisted within its fraught political connection with democracy and citizenship, ultimately threatening the planet. If theory is provocation as Norman suggests, my response to Žižek’s provocation and Norman’s explores democracy, learning and pedagogy, and the civic purpose of education, beyond citizenship. Žižek offers philosophical insight for educational researchers to reflect upon the place of democracy, the dangers of performativity, and the purpose of education for Australian citizens. In examining democracy, citizenship, and equity, my response draws upon the philosophical and spiritual insights of Illich (1970) (Bono, Surrender: 40 songs, one story. Hutchinson Heinemann, London, 2022) and other contemporary philosophers to rethink what it means to be human. I propose that what is of utmost importance to education is receptivity and listening in the creation of new voice, new art, and new songs.
After Belonging: Aileen Moreton-Robinson’s ‘I Still Call Australia Home’
Authors: Laurie Timothy 
Published: October 2023

AbstractA classroom can be a place to belong. Students become settled, ideas become familiar, relations become belongings. Teachers attentive to belonging can support critical conversations without fear that students will accidentally stumble onto alienating terrain. But the desire to settle, to make familiar, and to belong is not without its own ambivalence. For example, should non-Indigenous Australian students feel they ‘belong’ when engaging with the legacies of settler colonialism? Is learning about Aboriginal and Torres Strait Islander cultures and communities a desirable way for non-Indigenous students to feel settled in Australia? Aileen Moreton-Robinson’s work interrogates two impulses towards belonging among non-Indigenous Australians. On the one hand, she considers the erasure of Indigenous belonging through the legal fallacy of terra nullius and its subsequent variations in myths of British belonging to Australia. On the other hand, the essay questions non-Indigenous appeals to Indigenous communities as potential partners in national projects of collective belonging. Moreton-Robinson shows that non-Indigenous Australians ‘possess’ their symbolic home in the nation-state at the expense of Indigenous belonging. In what ways can non-Indigenous students be invited to question practices of belonging? What new classroom might this produce, and would everyone need to belong?
In Belonging: A Response to Timothy Laurie
Authors: Moran Gulwanyang 
Published: October 2023

AbstractIn response to Timothy Laurie’s After Belonging: Aileen Moreton-Robinson’s ‘I Still Call Australia Home’ (2015), this chapter reinforces the importance of the role of belonging and unbelonging in societal and educational contexts in Australia and builds on understanding Moreton-Robinson’s work and reference to Indigenous sovereignty through a First Nations’ lens. It positions the idea that epistemology and ontology without a consideration of practice maintain a superficial approach to education. Through this chapter it is asserted that Indigenous sovereignty, rather than the Australian nation-state, as the ground of belonging establishes and maintains a genuine and sustainable belonging for all who call this continent home.
Long-term Follow-up After Aneurysm Treatment with the Flow Redirection Endoluminal Device (FRED) Flow Diverter
Authors: Hohenstatt Sophia , Ulfert Christian , Herweh Christian , Hilgenfeld Tim , Schmitt Niclas , Schönenberger Silvia , Chen Min , Bendszus Martin , Möhlenbruch Markus A. , Vollherbst Dominik F. 
Published: October 2023

Abstract
Introduction
This study focuses on long-term outcomes after aneurysm treatment with either the Flow Re-Direction Endoluminal Device (FRED) or the FRED Jr. to investigate the durability of treatment effect and long-term complications.

Methods
This study is based on a retrospective analysis of a prospectively maintained patient data base. Patients treated with either FRED or FRED Jr. between 2013 and 2017 at our institution, and thus a possibility for ≥ 5 years of follow-up, were included. Aneurysm occlusion rates, recurrence rates, modified Rankin scale score shifts to baseline, and delayed complications were assessed.

Results
In this study 68 patients with 84 aneurysms had long-term follow-up with a mean duration of 57.3 months and 44 patients harboring 52 aneurysms had a follow-up ≥ 5 years with a mean follow-up period of 69.2 months. Complete occlusion was reached in 77.4% at 2 years and increased to 84.9% when the latest available imaging result was considered. Younger age and the absence of branch involvement were predictors for aneurysm occlusion in linear regression analysis. After the 2‑year threshold, there were 3 reported symptomatic non-serious adverse events. Of these, one patient had a minor stroke, one a transitory ischemic attack and one had persistent mass effect symptoms due to a giant aneurysm, none of these resulted in subsequent neurological disability.

Conclusion
This long-term follow-up study demonstrates that the FRED and FRED Jr. are safe and effective for the treatment of cerebral aneurysms in the long term, with high rates of complete occlusion and low rates of delayed adverse events.
Temporal and spatial changes in the provision of mental health care during the COVID-19 pandemic in Germany: a claims-based cohort study on patients with severe mental disorders
Authors: Engels Alexander , Stein Janine , Riedel-Heller Steffi G. , König Hans-Helmut , Konnopka Claudia 
Published: October 2023

Abstract
Purpose
Major lockdowns were imposed in Germany from March until May 2020 and from December 2020 until May 2021. We studied the influence of these lockdowns, the strain on intensive care units and the strictness of COVID-19-related containment strategies on the utilization of mental health care among patients with severe mental disorders.

Methods
We used health insurance claims data to identify n = 736,972 patients with severe mental disorders shortly before the pandemic and n = 735,816 patients a year earlier. We applied entropy balancing to adjust for baseline differences by district. For a 12-month follow-up, we modeled monthly changes in utilization through meta-analytic models using both the COVID-19 stringency index and intensive care unit cases per 100,000 inhabitants as predictors. Our outcomes were changes in psychiatric hospital days and time treated by outpatient psychiatrists.

Results
Psychiatric hospital days declined by at least 7.7% in all calender month during the pandemic. Peak reduction rates were observed in April (− 27.9%), May (− 22.3%) 2020 and January 2021 (− 18.3%). Utilization changes were associated with the stringency index and the second lockdown. Time treated by psychiatrists was shorter in April (− 16.2%) and May (− 11.5%) 2020 and in January 2021 (− 10.5%), which was partially offset by higher utilization in June and September 2020. These utilization changes were associated with the stringency index and the strain on intensive care units during both lockdowns.

Conclusion
Hospitals did not maintain the level of utilization during the pandemic, while outpatient psychiatrists adapted more quickly, presumably due to digital and telemedical care.
Defects and residual stresses finite element prediction of FDM 3D printed wood/PLA biocomposite
Authors: Morvayová Alexandra , Contuzzi Nicola , Casalino Giuseppe 
Published: October 2023

Abstract The exploited enthusiasm within the research community for harnessing PLA-based biocomposites in fused deposition modeling (FDM) is spurred by the surging demand for environmentally sustainable and economically viable materials across diverse applications. While substantial strides have been taken in unravelling the intricacies of the process-structure–property relationship, the intricate interdependencies within this context remain only partially elucidated. This current gap in knowledge presents formidable obstacles to achieving the pinnacle of quality and dimensional precision in FDM-fabricated specimens crafted from biocomposites. Despite the existence of numerous numerical models for simulating the FDM process, an unmistakable need exists for models that are custom-tailored to accommodate the distinct characteristics inherent to biocomposites. As a reaction to those pressing needs, this study presents a 3D coupled thermomechanical numerical model designed to predict dimensions, defect formation, residual stresses, and temperature in PLA/wood cubes produced by FDM, considering various process parameters and composite-like nature of wood-filled PLA filaments. The accuracy of the proposed numerical model was validated by comparing its results with experimental measurements of biocomposite cubes manufactured under the same process parameters. Encouragingly, the simulated dimensions showed a maximum relative error of 9.52% when compared to the experimental data, indicating a good agreement. The numerical model also successfully captured the defect formation in the manufactured cubes, demonstrating consistent correspondence with defects observed in the experimental specimens. Therefore, the presented model aims to substantially contribute to the progress in the field of additive manufacturing of PLA-based biocomposites.
Cytochrome P450 activity in rheumatoid arthritis patients during continuous IL-6 receptor antagonist therapy
Authors: Dunvald Ann-Cathrine Dalgård , Søltoft Kasper , Sheetal Ekta , Just Søren Andreas , Frederiksen Ida Emilie Brejning , Nielsen Flemming , Olsen Dorte Aalund , Madsen Jonna Skov , Hendricks Oliver , Stage Tore Bjerregaard 
Published: October 2023

Abstract

Background
Inflammation suppresses cytochrome P450 (CYP) enzyme activity, and single-dose interleukin 6 receptor antagonists (anti-IL-6R) reverse this effect. Here, we assess the impact of continuous anti-IL-6R therapy in patients with rheumatoid arthritis.

Methods
In a clinical pharmacokinetic trial, the Basel cocktail was administered before and after 3 and 12 weeks of anti-IL-6R therapy to assess CYP enzyme activity (registered in the ClinicalTrials.gov database (identifier NCT04842981) on April 13th, 2021). In a retrospective study, the 4β-hydroxycholesterol/cholesterol ratio was measured as a biomarker for CYP3A4 activity before and after 3 and 6 months of anti-IL-6R therapy. The control group was patients initiating a tumor necrosis factor alfa (TNF-α) inhibitor.

Results
In the clinical pharmacokinetic trial (n = 3), midazolam metabolic ratio (CYP3A4) was inconclusive due to the limited sample size. Midazolam AUC and Cmax indicate a weak impact on CYP3A4 activity after 3 weeks of anti-IL-6R therapy compared to baseline (AUC geometric mean ratio (GMR): 0.80, 95% CI: 0.64–0.99 and Cmax GMR: 0.58, 95% CI: 0.37–0.91), which returns to baseline levels after 12 weeks of therapy (AUC GMR 1.02, 95% CI: 0.72–1.46 and Cmax GMR 1.03, 95% CI 0.72–1.47). No effect on the 4β-hydroxycholesterol/cholesterol ratio was observed in the retrospective study.

Conclusion
Based on sparse data from three patients, continuous anti-IL-6R therapy seems to cause an acute but transient increase in CYP3A4 activity in rheumatoid arthritis patients, which may be due to a normalization of the inflammation-suppressed CYP activity. Further studies are warranted to understand the mechanism behind this putative transient effect.
Trial registration Registered in the ClinicalTrials.gov database (identifier NCT04842981) on April 13th, 2021.
Management of Tarlov cysts: an uncommon but potentially serious spinal column disease—review of the literature and experience with over 1000 referrals
Authors: Murphy Kieran , Nasralla Mehran , Pron Gaylene , Almohaimede Khaled , Schievink Wouter 
Published: October 2023

AbstractTarlov cysts were thought to be anatomic variants of uncertain etiology and clinical significance when initially described over 80 years ago. They are often detected in routine lumbosacral imaging and generally not reported in a differential diagnosis. There is increasing evidence that at least some Tarlov cysts are symptomatic and can have a significant adverse impact on patients’ health and well-being. Women are disproportionately affected with this condition, often presenting with long-standing pain and neurological dysfunctions. Significant gender bias has been a concern in the management of these patients. Unfortunately, there is no consensus on patient selection or management approaches for symptomatic Tarlov cysts. This review article updates information on the prevalence, diagnosis, clinical significance, and treatments of these cysts. Based on these findings and experience with over 1000 patient referrals, a treatment decision algorithm for symptomatic Tarlov cysts was constructed to provide guidance for appropriate management of patients with these complex cysts.