bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frameworks Construction with Rhodium‐Organic Cuboctahedra via Rigid Linker Incorporation
Authors: Lin Yu‐Shan , Lopez‐Cabrelles Javier , Lin Chia‐Her , Furukawa Shuhei 
Published: January 2025

AbstractThe architectural characteristics of metal‐organic frameworks (MOFs) can be examined through their net topology, which consists of nodes and linkers. A node‘s connectivity and site symmetry are likely the key elements influencing the net topology of MOFs. Metal‐organic polyhedra (MOPs) function effectively as nodes when used as supermolecular building blocks (SBBs). The SBB approach offers a powerful strategy for the deliberate design of macroscale materials, ranging from soft materials such as gels, polymers, and membranes to crystalline frameworks. However, achieving highly ordered structures with robust and air‐stable rhodium‐based MOPs (RhMOPs) presents a significant challenge. To investigate how to control the precise spatial distribution of RhMOPs as SBBs for constructing crystalline extended networks, here, we present a strategy for synthesizing MOFs by coordinating RhMOPs with rigid bridging linkers 1,4‐diazabicyclo[2.2.2]octane (dabco). The resulting crystalline framework exhibited high microporosity and four times higher adsorption capacity than the parent MOP solids.
Evaluation of the Role of PnuC Gene in Enhancing Nicotinamide Mononucleotide Synthesis
Authors: Vo Giang Thi Thu , Nguyen Khang Khoa Hoang , Kim Beom Soo 
Published: January 2025

ABSTRACTThe PnuC gene plays a crucial role in the complex processes related to the absorption and synthesis of the nicotinamide mononucleotide (NMN) precursor. NMN, a nicotinamide adenine dinucleotide (NAD+) precursor, is important for cellular energy metabolism, DNA repair, and antiaging. This study focuses on elucidating the precursor absorption mechanism and the specific function of the PnuC gene in encoding membrane transport proteins, as well as its impact on the regulation and dynamics of NMN within the cell. This understanding aims to provide insights into its potential effects on metabolic balance, illustrated through two NAD+ biosynthesis pathways based on renewable and readily available cytoplasmic resources, assessing the potential of PnuC gene expression in clarifying complex interactions within regulation mechanisms. Enhanced expression analysis of the PnuC gene has initiated discussions on its potential applications in treating aging‐related diseases and dysfunctions, contributing to cellular health maintenance.
Texturing (002)‐Oriented Zinc Atop a Cotton Cloth for High‐Performance Zn‐Ion Batteries
Authors: Kiatwisarnkij Napat , Song Zehao , Tangpongkitjaroen Chanin , Wannapaiboon Suttipong , Zhang Xinyu , Wangyao Panyawat , Qin Jiaqian 
Published: January 2025

AbstractZn‐ion batteries emerge as a promising alternative to conventional Li‐ion batteries due to their superior environmental friendliness and high safety, making them suitable for sustainable energy storage in various applications. However, concerns persist regarding the limitations of Zn‐ion batteries, such as uncontrolled dendrite growth and side reactions. In this study, the electroplating method was employed to deposit (002) plane‐dominated textures on a modified cotton cloth substrate, which consists of a silver conductive layer atop a cotton supporting layer. The electroplating current density and time are critical for the fabrication of dense and compact (002) Zn textures. The optimized condition for this process involves a current density of 40 mA/cm2 and an electroplating time of 30 minutes. Compared to (101)‐dominated Zn anodes, the (002)‐dominated electrode demonstrates faster deposition kinetics and lower charge transfer resistance, enabling denser and more uniform Zn deposition. Additionally, the (002)‐dominated electrode also exhibits an enhanced ability to inhibit side reactions in the mild aqueous electrolyte, further improving the lifespan of Zn‐ion batteries. This work demonstrates the feasibility of using ordinary cotton cloth as a substrate for electroplating (002)‐dominated Zn, thereby expanding the potential applications of Zn‐ion batteries.
Effects of washing treatments and ashing conditions on SiO2 crystalline transitions in rice husk ash
Authors: Wei Yi , Yin Yuan , Tahir Mudassir Hussain , Liu Xiang , Shi Lei , Wei Juntao , Hu Xun , Zhang Hong , Xu Deliang , Zhang Shu 
Published: January 2025

AbstractThis study investigated the influence of alkali and alkaline earth metals (AAEMs) on the structural transformation of silica (SiO₂) during the ashing of rice husks. It has implications for silicon‐based material development from thermal conversion. Utilizing water/acid‐washed treatments to remove AAEMs, the research assessed the effects of these treatments on the crystallization characteristics of SiO₂ in rice husk ash. The results showed a significant increase in SiO₂ crystallization temperatures under both slow and rapid ashing conditions, with acid washing having a more pronounced effect. The removal of K, a primary AAEM, was identified as a key factor in improving crystallization temperatures. The presence of K during rapid ashing aided the preservation of residual carbon, further influencing SiO₂ crystallization. Washing treatments and lower ashing temperatures also improved the pore structures of the ashes, thus enhancing the functional applicability of rice husk‐derived silicon materials.
Are Environmentally Sensitive Firms More Likely to Release Corporate Environmental Disclosures? Evidence From Environmental Risk Management
Authors: Chung Chune Young , Kim Incheol , Yang Rong 
Published: January 2025

ABSTRACTThis study examines the environmental risk management practices of US firms operating in environmentally sensitive industries. Using two proxy variables for ex ante environmental policy risk—firm‐level toxic chemical emissions and climate‐related keywords in annual financial statements—we demonstrate that firms facing high ex ante environmental policy risk tend to increase the frequency and length of their voluntary sustainability reports. Additionally, we find that proactive sustainability disclosures significantly mitigate firm‐level systematic risk (beta) and associated litigation risk. This risk reduction is more pronounced among firms with substantial green innovations and stronger corporate governance practices. Overall, this study highlights the causes and consequences of voluntary sustainability reports, focusing on how environmentally sensitive firms manage environmental risk through these publications.
Is Liability of Foreignness Always Bad for Firms? A Study of the Influence of Top Management Team Foreignness on Corporate Greenwashing
Authors: Song Jialei , Chen Shouming 
Published: January 2025

ABSTRACTThis study investigates the impact of top management team (TMT) foreignness on corporate greenwashing. Drawing on social identity theory, we argue that foreign TMT members, suffering more from individual liability of foreignness (LOF), adopt a more cautious approach to uncertain environmental disclosures and are more concerned with preventing corporate misbehaviors. These lead foreign TMT members to communicate companies' environmental initiatives in a more honest manner, thereby effectively reducing corporate greenwashing. We further propose that the negative relation between TMT foreignness and greenwashing will be strengthened when a firm faces higher earnings pressure and operates in a less marketized environment, as these conditions exacerbate individual LOF on foreign TMT members. Empirical analysis of a sample of Chinese listed companies from 2010 to 2022 confirms our arguments, suggesting that hiring foreign executives can be an effective strategy for mitigating greenwashing, particularly in contexts where individual LOF is more pronounced.
Mutations in Aristolochene Synthase Promote Hydroxylation of Aristolochene in Aspergillus oryzae
Authors: Anumon Thirat , Wattana‐Amorn Pakorn 
Published: January 2025

ABSTRACTA terpene synthase gene (mtas) from Menisporopsis theobromae BCC 4162 was heterologously expressed in Aspergillus oryzae NSAR1, resulting in the production of (+)‐aristolochene. Mutations were introduced in MtAS at aromatic residues (Y83, F103, F169 and W323) surrounding the active site, which are critical for precursor cyclisation and intermediate stabilisation during aristolochene biosynthesis. Transformants harbouring mutated mtas, specifically F103W, F169A and F169W, produced (2R,4S,5R,7S)‐2‐hydroxyaristolochene as the major product, along with aristolochene and other tentative metabolites, including germacrene A and sesquiterpenoids. Feeding experiments with (+)‐aristolochene in A. oryzae NSAR1 revealed that 2‐hydroxyaristolochene was only detected in trace amounts. This suggests that the oxidation products observed in this study are predominantly catalysed or facilitated by the mutated MtAS, differing from in vitro studies of other mutated aristolochene synthases. These findings highlight the impact of enzyme mutations on sesquiterpene production and suggest potential strategies for enhancing the diversity of sesquiterpenoids.
Necrotizing Fasciitis‐Induced Septic Shock due to Aeromonas hydrophila: A Case Report
Authors: Ye Gongjie , Li Taohong , Weng Yiru , Dong Zhouzhou 
Published: January 2025

ABSTRACTAeromonas hydrophila (A. hydrophila), a Gram‐negative bacterium commonly found in aquatic environments, has the capacity to be transmitted to humans through consumption of contaminated fish, water, or seafood. In this study, we present a case report concerning a 77‐year‐old female patient who experienced an acute exacerbation of chronic heart failure, subsequently developing severe septic shock due to necrotizing fasciitis caused by A. hydrophila. Infections caused by A. hydrophila are more prevalent during warmer months, particularly in regions characterized by dense aquaculture or the presence of natural water bodies. The excessive use of antibiotics in aquaculture has contributed to the emergence of antibiotic‐resistant A. hydrophila strains. The proliferation of multidrug‐resistant A. hydrophila presents a significant challenge for clinicians. In the context of atypical bacterial infections, the initial empiric therapy typically involves the use of third‐generation cephalosporins in conjunction with quinolone antibiotics. In the present case, the patient's successful recovery was achieved through the administration of a combination of cefoperazone/sulbactam and levofloxacin, as determined by sensitivity testing. This case study underscores the critical importance of considering A. hydrophila infection in patients with septic shock who present with necrotizing fasciitis.
A Rare Case Report on Massive Pleural Effusion due to Chronic Necrotizing Pancreatitis and its Management
Authors: Bhandari Kritick , Sen Kamana , Rijal Prabhat , Ghimire Sagun 
Published: January 2025

ABSTRACTHemorrhagic pleural effusion as the sole manifestation of pancreatitis is exceedingly rare and often presents diagnostic challenges due to its misleading symptoms. We report the case of an adult male with a large left‐sided black pleural effusion secondary to chronic necrotizing pancreatitis. The patient presented with progressive shortness of breath and cough, with a history of alcohol use and a previous diagnosis of acute severe pancreatitis. Initial assessment revealed significant respiratory distress and imaging confirmed massive pleural effusion. Pleural fluid analysis and subsequent imaging identified chronic necrotizing pancreatitis as the cause. Immediate management with thoracentesis, pleural drainage, and conservative treatment with fluids and antibiotics led to significant clinical improvement. This case highlights the importance of thorough clinical evaluation and timely intervention in managing rare presentations of pancreatic diseases. Effective treatment with chest tube drainage and conservative pancreatitis management can yield positive outcomes even in severe cases. Despite the rarity of pleural effusion due to chronic pancreatitis, clinicians should maintain a high index of suspicion, particularly in patients with a relevant history, to ensure prompt and appropriate management.
Unusual presentation of medication‐induced atrial fibrillation: A case report
Authors: Hashim Thamir , Yigit Yavuz , Fadul Khalid Yasir , Dayraki Mostafa , Elmalik Ashraf , Alkahlout Baha Hamdi , Mohammad Aftab 
Published: January 2025

Key Clinical MessageThis case highlights that atrial fibrillation can occur as an adverse effect of tamsulosin even in younger patients at lower doses, challenging the conventional understanding that this complication primarily affects older individuals on higher doses. Clinicians should remain vigilant for this potential side effect across all patient demographics to ensure prompt identification and management.
Primary Diffuse Leptomeningeal Melanomatosis Leading to Raised Intracranial Pressure in a Pediatric Patient
Authors: Sareh Shiva , Habibi Zohreh , Vasei Mohammad , Safavi Moeinadin , Sharari Alieh Safari , Pak Neda , Shahbodagh khan Golazin , Ashrafi Mahmoudreza , Heidari Morteza 
Published: January 2025

ABSTRACTA critical clinical consideration, in addition to other common risk factors predisposing individuals to idiopathic intracranial hypertension (IIH), involves the potential co‐occurrence of increased intracranial pressure and elevated cerebrospinal fluid protein levels in the presence of underlying malignancies. Primary diffuse leptomeningeal melanomatosis, an exceptionally rare condition with few reported cases in the pediatric population, illustrates this scenario. Timely decision‐making based on clinical suspicion to perform a biopsy and involving a skilled pathologist for accurate reporting are essential steps toward achieving a definitive diagnosis.
Site‐Selective Modification and Labeling of Native RNA
Authors: Kha Tuan‐Khoa , Zhao Yiran , Zhu Ru‐Yi 
Published: January 2025

AbstractRibonucleic acid (RNA) plays a pivotal role in regulating biological processes within living systems, with modified nucleosides serving as critical modulators of various aspects of biological functions. Therefore, the development of efficient methodologies for late‐stage, site‐selective RNA modification is of considerable interest, as it facilitates the functional exploration of RNA chemical modifications and their implications for therapeutic applications. Precise RNA modification holds significant promise for the treatment of genetic diseases by enabling the correction of mutated nucleobases to their wild‐type forms. Additionally, the site‐selective incorporation of synthetic labeling groups into RNA provides invaluable tools for structural and functional studies, thereby uncovering previously hidden dimensions of RNA′s role in biological systems. In this review, we provide a comprehensive overview of three principal approaches to site‐selective, late‐stage RNA modifications: enzyme‐mediated strategies, catalytic nucleic acid‐based techniques, and chemical methodologies. These approaches predominantly target the nucleobase or the 2’‐hydroxyl (2’‐OH) group of RNA nucleosides. We evaluate the advantages and limitations of each strategy and discuss future directions for advancing this field of research.
Synthesis and Characterization of a Non‐Planar Cyclophenylene on Au(111)
Authors: Salaverria Sergio , Irizar Martin , Janeiro Jesús , Angulo‐Portugal Paula , Wang Tao , Patrick Calupitan Jan , Rodríguez‐Fernández Jonathan , Garcia‐Lekue Aran , Corso Martina , Artacho Emilio , Peña Diego , Pérez Dolores , de Oteyza Dimas G. 
Published: January 2025

AbstractWe report the surface‐assisted synthesis of a non‐planar cyclophenylene derivative containing four meta‐ and two para‐ connected phenylene moieties on Au(111), via hierarchical Ullmann coupling of a 1,10‐dibrominated angular [3] phenylene and subsequent C−C bond cleavage at the four‐membered rings. Scanning tunneling microscopy and spectroscopy (STM/STS) were used for the characterization of its chemical structure and electronic properties. Density functional theory (DFT) calculations support the experimental observations.
Discovery of 1,3,4‐Oxadiazin‐5‐One Derivative CJ1‐34 as a Partial ATP Synthase Inhibitor for CNS Applications
Authors: Jie Caitlin V. M. L. , Delparente Aro , Reichert Lisa , Albrecht Manuela , Atz Kenneth , Schneider Gisbert , Schibli Roger , Mu Linjing 
Published: January 2025

AbstractATP synthase dysregulation has been implicated in many diseases, including cancer and neurodegenerative diseases. Whilst ATP synthase‐targeting compounds have been reported, most are large or polar compounds and lack appropriate properties for a CNS drug. We designed, synthesised, and evaluated a novel series of ATP synthase targeting compounds, resulting in a 1,3,4‐oxadiazin‐5‐one scaffold with improved physiochemical properties. In vitro evaluation of our library led to the discovery of CJ1‐34 as a partial ATP synthase inhibitor with a determined IC50 of 394 nM in isolated bovine mitochondria. Molecular docking experiments demonstrated that calculated docking scores aligned with the observed in vitro pharmacology and supports the F1 region of the ATP synthase as the potential binding site. Overall, this provides the foundation to further investigate CJ1‐34 as a potential CNS drug for diseases where mitochondria are implicated, including Alzheimer's and Parkinson's disease.
Two Consecutive Pathways Competing for Supramolecular Polymerization of Naphthalene‐Diimide Molecules
Authors: Huang Yun , Zhang Ruilong , Shi Chengyu , Wang Cong , Liao Rui , Zou Chongwen , Wang Feng , Huang Ningdong 
Published: January 2025

AbstractThe final outcomes of supramolecular assembly are determined by the pathways and the formation of intermediates during the assembly process. We studied pathway complexity involving two consecutive pathways in supramolecular polymerization of naphthalene‐diimide (NDI) derivative molecule. Depending on preparation methods anisotropic aggregates of J‐type nanorods (Agg I) or more flexible H‐type nanofibers (Agg II) are obtained from the identical initial state in solution of methyl cyclohexane (MCH) or MCH/CHCl3 mixtures. More interestingly intermediate aggregates driven by intra‐molecular hydrogen‐bonds are observed by spectroscopy and imaging techniques for both pathways. Thermodynamic model‐fitting suggests that both pathways are consecutive ones with intermediate aggregates. Combining density functional theory (DFT) calculation results, we propose the molecular packing of Agg I and II. Our results reveal comprehensive pathway complexity in self‐assembly of molecules as simple as NDI.
Fabrication of pH‐sensitive bacterial cellulose/carboxymethyl cellulose hybrid hydrogel beads in agitated culture for oral drug delivery
Authors: Sattari Ali , Basirattalab Ali , Alemzadeh Iran 
Published: January 2025

AbstractBacterial cellulose (BC), a biopolymer with unique properties, has been employed in numerous biomedical applications. Carboxymethyl cellulose was introduced to the agitated culture of Gluconacetobacter xylinus to produce pH‐responsive BC hydrogel beads. It was shown by x‐ray diffraction (XRD) analysis that adding carboxymethyl cellulose to the agitated culture increased the crystallinity of the hydrogel beads. Scanning electron microscopy exhibited the 3‐D porous structure of microfibrils and the reverse effect of adding carboxymethyl cellulose on the hydrogels' porosity. The hydrogels were loaded with ibuprofen sodium salt (IbuNa), and their release and swelling studies were conducted in the simulated gastric and simulated intestinal fluids. It was observed that by increasing the amount of carboxymethyl cellulose in the culture medium, the pH responsivity of the beads was increased. Thus, this study shows the potential of the BC/CMC system as an oral drug delivery system.
Fault diagnostic method based on transfer dynamic deep learning for few shot temporal–spatial correlation industry process
Authors: Tian Ying , Lou Yuanlong , Ou Jingyi , Huang Xiuhui , Sun Zhanquan 
Published: January 2025

AbstractData‐based fault diagnosis plays a crucial role in ensuring the safety of industrial processes. However, the complex industry process often has temporal–spatial correlation with insufficient labelled fault data. To settle these problems, a new transfer dynamic deep learning strategy that combines autoencoder (AE) with gate recurrent unit (GRU) is proposed. First, dynamic AE networks are introduced to extract the single‐attribute time series features, and the dynamic GRU is employed to extract the spatial correlation features among multiple feature dimensions and temporal correlation among samples. Then, to solve the problem of insufficiently labelled industrial data, the model‐based transfer learning between the sufficient laboratory data and insufficient labelled industrial data is executed. Experimental results based on the Tennessee Eastman (TE) process and the benchmark simulation model 1 (BSM1) process show that the proposed approach has excellent performance.
Functional Guest in Metal‐Organic Frameworks†
Authors: Han Zongsu , Huang Wenhao , Cheng Peng , Shi Wei 
Published: January 2025

Comprehensive SummaryMetal‐organic frameworks (MOFs) contain ordered metal nodes, organic linkers, and guest species, which generally determine their properties respectively and/or synergistically. Guest species play a crucial role in maintaining charge balance and structural stability of MOFs. In addition to metal nodes and organic linkers, the type and distribution of guests can significantly influence the properties of MOFs, such as optics, magnetism, chirality, and catalysis. Understanding the role of guests to the properties of MOFs remains great challenge due to the complex chemical and electronic structures of MOFs. Recently, progresses on guest‐dependent properties of MOFs have been reported, which not only advanced our knowledge of host‐guest interactions and energy transfer mechanisms but also led to intriguing applications such as luminescent sensors, tunable magnetic materials, enantioselective materials, and catalysts. Crucially, the interactions between the host and guest can be finely tuned by altering the type and amount of guests without changing the core framework, allowing for precise regulation of targeted properties. In this review, we will explore how guest‐induced variations impact the optic, magnetic, chiral, and catalytic properties of MOFs, followed by an examination of the synergistic effects between hosts and guests, which is highly important for the development of advanced functional materials.
Key ScientistsPlenty of outstanding scientists have reported a great number of MOFs with their interesting properties. Diverse regulation and modification strategies have been developed towards the metal centers, the organic linkers, and the functional guests according to the binding modes and host‐guest interactions, to bring or enhance certain properties of MOFs. Guests in the pores of MOFs are crucial part for their properties based on the guest‐induced properties or the synergistic effects between the hosts and guests, which has been greatly developed by their continuous industrious works.
Stories to be Continued …