bluuebunny/crossref_metadata_2025_split huggingface dataset:
Severe neutropenia with gelatinous bone marrow transformation in anorexia nervosa: A case report
Authors: Nishio Shinichiro , Yamada Hiroshi , Yamada Kaoru , Okabe Hirofumi , Okuya Takafumi , Yonekawa Osamu , Ono Takaaki , Sahara Naohi , Tamashima Sadahiro , Ihara Michio 
Published: March 2003

AbstractA 28‐year‐old woman with a history of anorexia nervosa was admitted with excessive weight loss, edema, and amenorrhea. She had lost 34% of her previous body weight within 2 years, and her body mass index was 12.3kg/m2. The leukocyte count on admission was 2150/μl and gradually decreased to 980/μl (neutrophils; 276/μl). Bone marrow biopsy disclosed gelatinous transformation with hypocellularity. After the patient was treated with intravenous nutritional support, the severe neutropenia improved to the level on admission. Hematological abnormalities seem to be common in anorexia nervosa, but severe neutropenia with gelatinous bone marrow transformation has rarely been reported. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 360–363, 2003.
Echocardiographic investigation of pericardial effusion in a case of anorexia nervosa
Authors: Inagaki Takuji , Yamamoto Masahiro , Tsubouchi Ken , Miyaoka Tsuyoshi , Uegaki Jun , Maeda Takahiro , Horiguchi Jun , Yamane Yuko , Kato Yuzuru 
Published: March 2003

AbstractObjectivePericardial effusion has recently been reported as a complication of anorexia nervosa. A distinct pathophysiological cause of it could not be revealed. In some reports, there was a probable correlation between weight gain and reduction of pericardial effusion in anorexia nervosa cases. We encountered a case in which pericardial effusion remitted completely along with body weight increase and normalization of low T3 syndrome. These findings suggest that the reduction of pericardial effusion may correlate with both weight gain and low T3 normalization. Plasma brain natriuretic peptide (BNP) levels were increased in this case despite heart failure, and plasma BNP decreased as pericardial effusion remitted. The measurement of serum BNP level may be a clinical parameter in such a case of pericardial effusion. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 364–366, 2003.
Neuroticism and low self‐esteem as risk factors for incident eating disorders in a prospective cohort study
Authors: Cervera Salvador , Lahortiga Francisca , Angel Martínez‐González Miguel , Gual Pilar , Irala‐Estévez Jokin de , Alonso Yolanda 
Published: March 2003

AbstractObjectiveTo assess the role of neuroticism and low self‐esteem as risk factors for eating disorders (ED).MethodA representative sample of girls 12–21 years old from Navarre, Spain. Girls free from any ED in 1997 were followed up for 18 months and reevaluated using DSM‐IV criteria. Multivariable logistic models were used to examine associations between neuroticism (Eysenck Inventory) or low self‐esteem (36‐item scale) and incident ED.ResultsHigher levels of neurotic personality increased the risk of ED (adjusted odds ratio [OR] for the highest quartile, 3.3; 95% Cl; 1.6–4.8). High levels of self‐esteem were protective (OR, 0.32; 95% CI, 0.16–0.66). Neuroticism was a more powerful predictor than low self‐esteem.DiscussionOur results provide prospective evidence supporting the role of neuroticism and low self‐esteem as major determinants of ED. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 271–280, 2003.
Body image dissatisfaction and disordered eating in black and white women
Authors: Perez Marisol , Joiner Thomas E. 
Published: March 2003

AbstractObjectiveThis study predicted and found that body image dissatisfaction and bulimic symptoms have a curvilinear relationship among undergraduate women.ResultsFor the women in this sample, regardless of race, body image dissatisfaction correlated with bulimic symptoms, such that women who perceived themselves as bigger or smaller than the ideal body size for their ethnic group endorsed bulimic symptoms. Black and white women differed regarding their ethnic group's ideal body image and their self‐perceptions of how they compared with the ideal image. Black women tended to report being underweight, whereas white women tended to report being overweight.DiscussionThe findings in this study suggest that some black women are not buffered against eating disorders as suggested in previous research. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 342–350, 2003.
Cognitive impairment in anorexia nervosa is not due to depressed mood
Authors: McDowell Bradley D. , Moser David J. , Ferneyhough Karin , Bowers Wayne A. , Andersen Arnold E. , Paulsen Jane S. 
Published: March 2003

AbstractObjectivePrevious research has revealed cognitive deficits in patients with anorexia nervosa. It is unclear whether these deficits are linked to co‐morbid depression in this population. We examined the relationship between depressive symptoms and cognitive functioning.MethodA large sample of subjects (N = 98) was examined using a common measure of cognitive ability and two measures of depression.ResultsWe confirmed that there is no relationship between depression and cognitive ability in this group.Discussion This suggests that alternative explanations be explored for cognitive deficits in patients with anorexia nervosa. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 351–355, 2003.
Sonovoltammetric Elucidation of Electron Transfer Rates: The Oxidation of Dimethyl‐p‐phenylenediamine in Aqueous Solution
Authors: Banks Craig E. , Lawrence Nathan S. , Compton Richard G. 
Published: March 2003

AbstractThe electrochemical oxidation of dimethyl‐p‐phenylenediamine (DMPD) in aqueous solution (pH 7 phosphate buffer) has been studied under conventional hydrodynamic and microelectrode voltammetric conditions and found to undergo a two‐electron electrochemically reversible oxidation. Upon the application of ultrasound to the system an observed shoulder emerges in the oxidation wave. This effect has been attributed to the resolution of the two‐electron transfer processes occurring: the first a relatively fast electron transfer (0.1 cm s−1) followed by a second slower (10−3 cm s−1) electron transfer: under the very high mass transport rates induced by insonation an overpotential develops for the second electron transfer so leading to the observed voltammetric resolution. The range of mass transport conditions accessible via sonication allows the estimation of the two rate constants reported.
Electron Transfer Kinetics of Ferrocene at Microcrystalline Boron‐Doped Diamond Electrodes: Effect of Solvent and Electrolyte
Authors: Haymond Shannon , Babcock Gerald T. , Swain Greg M. 
Published: March 2003

AbstractCyclic voltammetric measurements were made using well‐characterized microcrystalline boron‐doped diamond thin‐film electrodes to test the material's responsiveness for ferrocene as a function of scan rate, solvent, and electrolyte composition. Apparent heterogeneous electron transfer rate constants, k°app, of 0.042±0.015, 0.048±0.015, and 0.008±0.002 cm/s were observed in 0.1 M NaClO4/CH3CN, 0.1 M TBAClO4/CH3CN, and 0.1M TBAClO4/CH2Cl2, respectively. These rate constants, obtained using electrodes without any type of pretreatment, are similar to those observed for freshly polished glassy carbon. The results demonstrate that boron‐doped diamond is a viable material for the electrochemical analysis of nonaqueous analytes.
Polypyrrole Bilayers: Charge Trapping and Application for Amperometric Ions Sensing
Authors: Malinowska Beata , Maksymiuk Krzysztof 
Published: March 2003

AbstractBilayers composed of polypyrrole: doped by perchlorate ions (PPy(ClO4) – anion exchanging inner layer) and by dodecyl sulfate ions (PPy(DS) – cation exchanging outer layer) are very effective charge trapping systems that are usually not observed for other bilayers comprised of polypyrrole. Chronopotentiometric experiments carried out for oxidation and reduction showed that the trapping effect in the inner layer resulted from different ion exchange properties of the component polymers, leading to a low permeability of the reduced outer layer towards anions. Estimated diffusion coefficients of Cl− anions in the oxidized and reduced PPy(DS) are in the range of 10−9 and lower than 10−10 cm2 s−1, respectively. The presence of the outer layer limiting the ion transfer was found to be beneficial to improve the signal resolution in amperometric mode of ion sensing within wide KCl concentration range, from 10−5 M up to 3 M. The influence of experimental conditions (film thickness, response time) on optimization of this novel kind of polymeric bilayer ion sensors was studied.
Square‐Wave Voltammetry of the Molybdenum‐1,10 Phenanthroline‐Fulvic Acids Complex: Redox Kinetics Measurements
Authors: Quentel François , Mirčeski Valentin , Laouenan André , Elleouet Catherine , Madec Christian Louis 
Published: March 2003

AbstractThe reduction process of molybdenum in the presence of fulvic acids and phenanthroline was investigated by square‐wave voltammetry (SWV). The mixed‐ligand complex of molybdenum exhibits a pronounced tendency to adsorb onto the mercury electrode surface. The electrode reaction proceeds as a surface process in which both components of the redox couple are firmly confined to the electrode surface. The kinetics of the electrode reaction is studied utilizing the properties of “split SW peaks” and “quasireversible maximum”. The kinetic parameters obtained with two different square‐wave voltammetric methods are in good agreement. In 0.5 mol/L NaCl solution with pH 2.5 the kinetic parameters are: standard rate constant ks=8±2 s−1, cathodic electron transfer coefficient α=0.41±0.05, and number of exchanged electrons n=2. The SW kinetic measurements are confirmed by cyclic voltammetric method.
Homooxacalix[3]arene Derivatives as Ionophores for Serotonin‐Selective Membrane Electrodes
Authors: Katsu Takashi , Ido Kazuyuki , Sagara Sachie , Tsubaki Kazunori , Fuji Kaoru 
Published: March 2003

AbstractHomooxacalix[3]arene derivatives are effective ionophores for constructing serotonin‐selective membrane electrodes. An electrode based on one of the derivatives, tris(methoxyphenylpropyloxy)hexahomooxacalix[3]arene‐triethyl ether, with potassium tetrakis(p‐chlorophenyl)borate (20 mol% relative to the ionophore) as an ionic additive and bis(2‐ethylhexyl) sebacate as a solvent mediator in a poly(vinyl chloride) membrane matrix, displayed much better selectivity for serotonin than for various organic ammonium ions and inorganic cations. The electrode exhibited a near‐Nernstian response to serotonin in the concentration range of 2×10−4 to 1×10−2 M with a slope of 56.4 mV per concentration decade in physiological saline containing 150 mM NaCl and 10 mM Na2HPO4/NaH2PO4 (pH 7.4). The limit of the detection was 8×10−5 M. The selectivity pattern of this electrode was quite different from that of an electrode using calix[6]arene‐hexaacetic acid hexaethyl ester, a well‐known ionophore for primary organic ammonium ions, which did not induce an enhanced response to serotonin. The developed electrode was used for the active loading of serotonin in liposomes induced by transmembrane pH gradients.
Recognition of Monohydrogen Anions of Geometrical and Positional Isomers of Dicarboxylic Acids Based on Polymeric Liquid Membranes Incorporating Polyamine Host
Authors: Szymanska Iwona , Radecka Hanna , Radecki Jerzy , Pietraszkiewicz Marek , Pietraszkiewicz Oksana 
Published: March 2003

AbstractMacrocyclic lipophilic polyamines were applied as the sensory elements of polymeric liquid membrane electrodes. These hosts gain the anion receptor functionality upon protons uptake from the aqueous solutions. The electrodes studied were able to distinguish potentiometricaly isomers of monocharged and doublecharged forms of ethylene and benzene dicarboxylic acids. The selectivity of interaction between protonated hosts and anionic guests relays not only on the electrostatic interactions, but on hydrogen bounds formations as well. The influence of lipophilicity of protonated hosts on the potential response generation was discussed.
Polarographic Detection of Arenediazonium Ions. Optimization of the Method and Application for Investigating Dediazoniation Mechanisms
Authors: Bravo‐Díaz Carlos , González‐Romero Elisa 
Published: March 2003

AbstractThe use of differential pulse polarography (DPP) at the dropping mercury electrode (DME) to detect and to investigate the mechanisms for decomposition of arenediazonium ions, ArN2+, under different experimental conditions is discussed. The effect of a number of experimental and instrumental parameters on the polarographic peaks of a model arenediazonium ion was explored and representative applications to investigate their reaction mechanisms are given. The composite data shows that DPP provides an alternative, relatively cheap, technique to monitor ArN2+ decomposition in, for example, opaque systems where, for obvious reasons, spectroscopic detection does not work; meanwhile in homogeneous systems, DPP complements the results obtained by employing spectroscopic or chromatographic techniques. In addition, a variety of valuable mechanistic information such as detection of transient intermediates or estimation of the binding constants of aryl radicals with macromolecular systems, that otherwise cannot be easily obtained, is readily available by using DPP.
Partial filling‐micellar electrokinetic chromatography optimization studies of ibuprofen, codeine and degradation products, and coupling to mass spectrometry: Part II
Authors: Stubberud Karin , Callmer Karin , Westerlund Douglas 
Published: March 2003

AbstractWe describe the use of partial filling‐micellar electrokinetic chromatography‐mass spectrometry (PF‐MEKC‐MS) on the pharmaceutical ingredients ibuprofen and codeine phosphate as well as their degradation products and impurities. The study focuses on the change of the borate buffer to the volatile ammonium acetate and the optimization of critical MS parameters. The sensitivity of the method is also evaluated. The results are compared to an existing MEKC‐UV method that is used for quantitative determination of the two main substances as well as for the analysis of the degradation products. It is concluded that the PF‐MEKC‐MS system is suitable for separation and identification.
Detection of chlorinated quinones using interdigitated electrodes coupled with capillary electrophoresis
Authors: Male Keith B. , Luong John H. T. 
Published: March 2003

AbstractAn array of eight interdigitated microband gold electrodes (IDEs) has been developed together with electrophoretic separation for analysis of chlorinated hydroquinones (ClHQs) and benzoquinones (ClBQs). The IDE chip positioned very close to the separation capillary outlet served as an amplification/detection system without the requirement for frequent “capillary‐electrode” alignment. ClHQs, electrophoretically migrating to the IDE surface, were oxidized at +1.1 V by seven electrodes of the array and then detected by the remaining electrode, poised at –0.1 V. Conversely, ClBQs were detected at +1.1 V by the detecting electrode after having been reduced at the 7 adjacent electrodes poised at –0.1 V. There was an amplification effect on both the detecting electrode as well as the adjacent electrodes because of the recycle between ClHQs and ClBQs. The detecting “amplification” current response was dependent on the potentials applied, the position of the detecting electrode on the array, the number of adjacent electrodes being used for recycling and the distance between the oxidative and reductive electrodes. Micellar electrokinetic chromatography (MEKC) separation of the analytes was achieved using 30 mM sodium dodecyl sulfate (SDS) with a detection limit in the range of 2–20 μM. In addition to a facile “capillary‐electrode” alignment, the important aspect described here was the capability of detecting through recycling a reduced compound (in the case of ClHQs) at a negative potential to circumvent fouling and electroactive interferences. An appealing feature was also the concurrent oxidation/reduction detection for each compound to ascertain peak assignment, as interfering compounds are less likely to exhibit the same oxidative/reductive characteristics and electrophoretic mobilities as the target analytes.
On‐line identification of lysergic acid diethylamide (LSD) in tablets using a combination of a sweeping technique and micellar electrokinetic chromatography/77 K fluorescence spectroscopy
Authors: Fang Ching , Liu Ju‐Tsung , Lin Cheng‐Huang 
Published: March 2003

AbstractThis work describes a novel method for the accurate determination of lysergic acid diethylamide (LSD) in tablets. A technique involving sweeping‐micellar electrokinetic chromatography (MEKC) was used for the initial on‐line concentration and separation, after which a cryogenic molecular fluorescence experiment was performed at 77 K. Using this approach, not only the separation of LSD from the tablet extract was achieved, but on‐line spectra were readily distinguishable and could be unambiguously assigned. The results are in agreement with analyses by gas chromatography‐mass spectrometry (GC‐MS). Thus, this method, which was found to be accurate, sensitive and rapid, has the potential for use as a reliable complementary method to GC‐MS in such analyses.
Determination of lysergic acid diethylamide (LSD) in mouse blood by capillary electrophoresis/ fluorescence spectroscopy with sweeping techniques in micellar electrokinetic chromatography
Authors: Fang Ching , Liu Ju‐Tsung , Chou Shiu‐Huey , Lin Cheng‐Huang 
Published: March 2003

AbstractThe separation and on‐line concentration of lysergic acid diethylamide (LSD) in mouse blood was achieved by means of capillary electrophoresis/fluorescence spectroscopy using sodium dodecyl sulfate (SDS) as the surfactant. Techniques involving on‐line sample concentration, including sweeping micellar electrokinetic chromatography (sweeping‐MEKC) and cation‐selective exhaustive injection‐sweep‐micellar electrokinetic chromatography (CSEI‐sweep‐MEKC) were applied; the optimum on‐line concentration and separation conditions were determined. In the analysis of an actual sample, LSD was found in a blood sample from a test mouse (0.1 mg LSD fed to a 20 g mouse; ∼1/10 to the value of LD50). As a result, 120 and 30 ng/mL of LSD was detected at 20 and 60 min, respectively, after ingestion of the doses.
Analysis of lignans using micellar electrokinetic chromatography
Authors: Kuo Ching‐Hua , Lee Shoei‐Sheng , Chang Hsing‐Yun , Sun Shao‐Wen 
Published: March 2003

AbstractMicellar electrokinetic chromatography (MEKC) was used to separate twelve lignan compounds originating from Phyllanthus plants. To increase the reliability of peak identification, two micellar systems, the sodium dodecyl sulfate (SDS) and sodium deoxycholate (SDC) systems, were investigated. Because of the high lipophilicity of the lignan analytes, tetrahydrofuran was added to the SDS micellar system to increase its separating ability. In contrast to SDS system, no organic solvent was needed with SDC micelles. Both micellar systems gave a satisfactory separation within a reasonable analysis time. On considering accuracy for quantitation, the SDS method was validated and then used to determine the content of the lignans in two Phyllanthus plants. The selectivity (elution order of the lignans) was significantly different between the SDS and SDC micellar systems. Retention in SDC‐MEKC seemed to be dominated by the hydrophobicity of the lignan solutes, while in SDS‐MEKC, retention was greatly influenced by hydrogen bonding interactions.
Enantiomeric separations using polymeric L‐glutamate surfactant derivatives: Effect of increasing steric factors
Authors: Thibodeaux Stefan J. , Billiot Eugene , Torres Eric , Valle Bertha C. , Warner Isiah M. 
Published: March 2003

AbstractThis study examines the role of steric hindrance near the stereogenic centers of four glutamic acid based polymeric surfactants. The single amino acid surfactants of glutamic acid, glutamic acid methyl ester, glutamic ethyl ester, and glutamic acid tert‐butyl ester were investigated. The micellar electrokinetic chromatography (MEKC) separation of three binaphthyl derivatives and three benzodiazepines were used to study these steric factors. In addition, the hydrophobicity of these polymers as a function of pH was investigated by use of fluorescence measurements.
Comparative enantioseparations with native β‐cyclodextrin, randomly acetylated β‐cyclodextrin and heptakis‐(2,3‐di‐O‐acetyl)‐β‐cyclodextrin in capillary electrophoresis
Authors: Chankvetadze Bezhan , Lomsadze Ketevan , Burjanadze Naira , Breitkreutz Joerg , Pintore Giorgio , Chessa Mario , Bergander Klaus , Blaschke Gottfried 
Published: March 2003

AbstractComparative enantioseparations were performed with three neutral cyclodextrins (CDs) in capillary electrophoresis (CE). In particular, native β‐CD was compared with single component heptakis(2,3‐di‐O‐acetyl)‐β‐CD (HDA‐β‐CD) and randomly acetylated β‐CD (Ac‐β‐CD) with the emphasis on the enantiomer migration order. The opposite affinity of the enantiomers of several chiral analytes was observed towards native β‐CD and its acetylated derivatives. The enantiomer affinity pattern of some chiral analytes was also opposite towards the two acetylated derivatives of β‐CD. In the case of the chiral drug clenbuterol (CL) an attempt was made to evaluate the possible structural reasons of the affinity reversal using one‐ and two‐dimensional as well as transverse rotating frame nuclear Overhauser effect spectroscopy (ROESY). Significant differences were observed between the structure of the CL complexes with β‐CD and HDA‐β‐CD.
Capillary electrophoretic separation of glutamate enantiomers in neural samples
Authors: Quan Zhe , Liu Yi‐Ming 
Published: March 2003

AbstractA micellar electrokinetic chromatographic (MEKC) separation of glutamate (Glu) enantiomers fluorescently tagged with naphthalene‐2,3‐dicarboxaldehyde (NDA) is described. Chiral selectors tested included α‐, β‐, and γ‐cyclodextrins, modified cyclodextrins, D‐glucosamine, sucrose, taurocholate, and their binary mixtures. NDA‐labeled Glu enantiomers were best resolved with β‐cyclodextrin in the presence of methanol as an organic modifier. Under the separation conditions, no other amino acids coelute with Glu enantiomers. Using NDA as the reagent, the labeling reaction proceeded readily in aqueous solution, and the spectroscopic properties of NDA fluorophore were optimum for the sensitive laser‐induced fluorescence (LIF) detection. Glu enantiomers present in mass limited samples such as single neurons could be adequately quantified by coupling this separation with LIF detection. A detection limit of 0.57 μM Glu was obtained. Using the present method, D‐Glu was detected in rat brain, and, for the first time, in ganglia and single neurons of Aplysia californica, an extensively studied neuronal model. Interestingly, the level of D‐Glu was found to be higher than that of L‐Glu in many Aplysia neurons.