bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Nd2O3 on physical properties of lead borate glass system
Authors: Marzuki Ahmad , Astuti Retno Willy , Fausta Devara Ega , Kasy Fransisca Indraningsih , Mahasindi Melya Ayu 
Published: January 2024

<p class="15"><span>The Nd</span><sub><span>2</span></sub><span>O</span><sub><span>3</span></sub><span> doped lead borate glass with composition 45B</span><sub><span>2</span></sub><span>O</span><sub><span>3</span></sub><span>-(40-x)PbO-11ZnO-4Na</span><sub><span>2</span></sub><span>O-xNd</span><sub><span>2</span></sub><span>O</span><sub><span>3</span></sub><span> (x=0; 0.5; 1.0; 1.5; 2.0; 2.5) mol% were fabricated using melt quenching method at 950</span><sup><span>o</span></sup><span>C for 35 minutes. The characterization of physical properties of glasses doped Nd</span><sub><span>2</span></sub><span>O</span><sub><span>3 </span></sub><span>were measured by density (ρ) based on the Archimedes principle. The other physical parameters such as molar volume (Vm), oxygen packing density (OPD), polaron radius (r</span><sub><span>p</span></sub><span>), ionic radius (r</span><sub><span>i</span></sub><span>), field strength (F), molar refraction (R</span><sub><span>m</span></sub><span>), and metallization (M</span><sub><span>n</span></sub><span>) were calculated using equation which derived from density. According to the measurement, the density of glasses decreased from 5.774 to 4.527 gr/cm3 while molar volume oppositely increased from 23.17 to 30.18 cm</span><sup><span>3</span></sup><span>/mol due to atomic mass of Nd (144.24) smaller than Pb (207.2). Along with the increase of molar volume, there were decreasing of the OPD, the polar radius (1.731 <span style="font-family: 'Times New Roman';">－</span><span style="font-family: Times;">1.095) Å and the ion radius (4.296</span><span style="font-family: 'Times New Roman';">－</span><span style="font-family: Times;">2.717) Å iof glasses Meanwhile, the field strength and metallization properties of the glasses increased as a result of the reduction r</span></span><sub><span>p</span></sub><span> and r</span><sub><span>i</span></sub><span>. The investigation of molar refractive shows an increasing trend because the addition of the concentration Nd</span><sub><span>2</span></sub><span>O</span><sub><span>3.</span></sub></p>
Analisis Sosiologi Lingkungan Terhadap Pemburuan Biawak (Varanus Salvator) Bagi Keberlanjutan Ekosistem Sungai
Authors: Muhammad Syamsudin  , Muhammad Labibun Nuful  , Ahmad Fauzan Hidayatullah  
Published: January 2024

Biawak dianggap sebagai hama dan populasinya masih banyak, apabila perburuan dilakukan terus menerus tidak menutup kemungkinan akan berakibat pada kepunahan. Biawak termasuk memiliki peran yang cukup penting dalam ekosistem sungai, seperti pemakan bangkai hewan-hewan yang ada disungai dan juga bisa mengendalikan populasi ular dengan memakan telur-telur ular. Penelian ini menerapkan metode kualitatif dengan pengumpulan data nya menggunakan observasi, wawancara dan juga dokumentasi kami melakukan observasi dengan terjun kelapangan tepatnya di Sungai Beringin, kemudian melakukan wawancara kepada masyarakat setempat dan juga pemburu yang biasa melakukan perburuan di sekitar sungai tersebut dan untuk dokumentasi nya berupa foto dari sungai Bringin sebagai pelengkap data penelitian ini. Hasil penelitian kami dapat kesimpulan bahwa kegiatan berburu yang dilakukan oleh warga adalah hal yang membuat ekosistem sungai terganggu dan populasi biawak semakin berkurang. Salah satu cara yang baik adalah semua warga harus bisa mengurangi dan mengingatkan apabila ada pemburuan terjadi di sungai beringin.
COVID-19 Pandemic: Duration and Epidemiological Forecast
Authors: Toporkov V. P. 
Published: January 2024

The World Health Organization declared COVID-19 a pandemic on March 11, 2020. While in March 2022, i.e. approximately two years later, the global dominance of the phylogenetic variant of SARS-CoV-2 Omicron with its associated milder clinical course of the disease was registered, and therefore an epidemiological forecast was made about the onset of a period of decline in the pandemic.The aim of this work was to determine the duration and possibility of predicting the COVID-19 pandemic based on an epidemiological assessment of its dynamics in the context of the wave-like course, phase nature, and epidemiological significance of the phylogenetic transformations of the pathogen. Materials from a global source on the Internet about daily cases of infection/deaths of COVID-19, the results of phylogenetic studies of the pathogen and their interpretation using the epidemiological method were analyzed. The evaluation of the COVID-19 pandemic dynamics in the world revealed that it is a typical epidemiological variant of pandemics (epidemics) with its characteristic waves that last for months and do not coincide with the annual solar cycles. As of early March 2023, 7 waves were registered, of which the 1st–4th waves are the epidemic phase, caused by the consistent dominance of the Wuhan and Delta strains, the 6th–7th waves are the post-epidemic phase. The waves varied in duration from 4 to 7 months (M – 4.6 months) and in amplitude from 307205 to 4082344 (M – 1331389.14) peak values of the number of the infected and deaths – from 2997 to 20702 (M – 10506), accordingly. The post-epidemic phase was characterized by a steady trend of quantitative decrease in SARS-CoV-2 Omicron in the form of undulating dynamics with steadily decreasing amplitude of the waves of the number of infected people against the background of a sharp decrease in the number of lethal outcomes compared to the epidemic phase. The continuation of this trend is expected in the form of two more waves of small amplitude (8th and 9th) with a total duration of about 10 months; the completion of the postepidemic phase is predicted in the first half of 2024. Data on the phase nature of the pandemic, determined by genomic changes in the pathogen, are necessary to be prepared for future pandemics.
Acceptance of e-Learning and Associated Factors among Postgraduate Medical and Health Science Student's at First Generation Universities, Amhara Region, 2023 Using Modified Technology Acceptance Model
Authors: Mitiku Abebaw Belew , Ketemaw Asmamaw , Sitotaw Getachew , Alganeh Habitamu , Wogayehu Biruk , Ayenew Temesgen , Walle Agmasie Damtew 
Published: January 2024

Abstract

Background
Electronic learning, also known as e-learning, is the process of remotely teaching and learning through the use of electronic media. University students are voracious information seekers who are eager to learn new concepts, ideas, technologies, and methods of knowledge acquisition. Students can access their learning materials at any time and from any location through e-learning, which takes place on the Internet. In a world where having up-to-date information and expertise is critical for benefiting from the current knowledge-based economy, e-learning is critical.
Methods
An institutional-based cross-sectional study was conducted from March 15 to April 20, 2023 in Amhara region first generation universities, Ethiopia. A total of 659 students participated in the study. simple random sampling technique was used. A self-administered questionnaire in Amharic language was used to collect data. data was manually coded and clean then entered into Epi data version 4.6 and SPSS version 25 was used for further analysis. A median score was used to assess the proportion of acceptance. A SEM analysis was employed to test, the proposed model and the relationships among factors using AMOS version 26.
Result
The proportion of postgraduate students’ acceptance to use e-learning was 60.7%, 95%CI (56.9–64.4). The SEM analysis had shown that accessibility (β = 0.216, P < 0.001), computer self-efficacy(β = 0.156, P < 0.01) and facilitating condition (β = 0.381, P < 0.001), had a positive direct relationship with perceived ease of use and facilitating condition (β = 0.274, P < 0.001), computer self-efficacy(β = 0.426, P < 0.001) and Perceived ease of use (β = 0.201, P < 0.001) had a positive direct relationship with perceived usefulness and also Perceived ease of use (β = 0.156, P < 0.001) and perceived usefulness (β = 0.606, P < 0.001) had a positive direct relationship with attitude. Perceived ease of use (β = 0.183, P < 0.001), attitude (β = 0.353, P < 0.001) and perceived usefulness (β = 0.307, P < 0.001) had a positive direct relationship with acceptance of e-learning.
Conclusion and recommendation:
Overall, proportion of postgraduate students’ acceptance of e-learning is promising. facilitating condition, self-efficacy, perceived usefulness, perceived ease of use and attitude had a positive direct and indirect effect on acceptance of e-learning, and attitude played a major role in determining students’ acceptance of e-learning. Thus, the implementers need to give priority to enhancing, the provision of devices, students’ skills, and knowledge of e-learning by giving continuous support to improve students’ acceptance to use e-learning.
Whole lung lavage and GM-CSF use for pulmonary alveolar proteinosis in an infant with lysinuric protein intolerance: a case report
Authors: Vojcek Eszter , Krikovszky Dóra , Lódi Csaba , Kovács Lajos , Schnur János , Szabó Attila J. 
Published: January 2024

Abstract
Background
Lysinuric protein intolerance (LPI) is a multi-organ metabolic disorder characterized by the imbalance in absorption and excretion of cationic amino acids like lysine, ornithine and arginine. Infants with LPI typically present with recurrent vomiting, poor growth, interstitial lung disease or renal impairment. The early onset of pulmonary alveolar proteinosis (PAP) has been reported to be associated with a severe form of LPI. Treatment of PAP most commonly consists of whole-lung lavage (WLL) and granulocyte-macrophage colony stimulating factor (GM-CSF) administration. Inhaled GM-CSF has not been extensively studied in infants.
Case presentation: We describe the case of an 8-month-old infant presenting with respiratory failure due to LPI associated with PAP, who was twice treated with WLL; firstly, while on veno-venous ECMO assistance and then by the use of a selective bronchial blocker. After the two treatments with WLL, she was weaned from respiratory support while on initially subcutaneous, then on inhaled GM-CSF therapy.
Conclusions
This case supports the notion that inhaled GM-CSF may be used in the treatment of PAP and represents a potentially safe and effective therapeutic option for the chronic care of patients with LPI and PAP after their respiratory stabilization with the use of WLL.
Resourceful cleaner preparation of Sb2O3 with vacuum vaporization- condensation from hazardous arsenic antimony dust
Authors: Li Shaoxiong , Kong Xiangfeng , Fan Kai , Yi Jiafei , He Mingyu , Gao Zhe , San Tongyu , He Yuhong , Ma Baozhong , Yang Bin , Liu Dachun 
Published: January 2024

Abstract

Hazardous arsenic antimony dust (HAAD), a perilous by-product with significant antimony and arsenic concentrations generated in smelters, poses a substantial environmental threat. The imperative of resource recycling and the innocuous processing of HAAD stand as prevalent challenges and pressing priorities. This study introduces an innovative vacuum vaporization-condensation technique, capitalizing on the intrinsic merits of vacuum metallurgy, to synthesize Sb2O3. ICP analysis evidenced an enhancement in the purity of the Sb2O3 product from an initial 73.96–91.35%, with a concomitant reduction in As impurities from 18.10–6.20%, and residual contaminants approximating 0.17% following a dual-phase vacuum vaporization-condensation process at divergent temperatures. XRD assessments affirmed the feasibility of direct Sb2O3 synthesis via vapor-phase migration and condensate amalgamation, achieving substantial As2O3 impurity diminution. SEM and EPMA observations underscored a homogenous particulate morphology in the refined Sb2O3. Incomplete As extraction from the refined Sb2O3 product was attributed to the persistence of (As, Sb2)O4.5, accompanied by partial Sb attrition throughout the fabrication sequence. The suboptimal partitioning efficacy of (As, Sb2)O4.5 warrants further investigation. This methodology underscores its environmental compatibility, characterized by zero gaseous effluent, absence of wastewater expulsion, and elimination of reagent usage, thereby mitigating environmental detriments and paving the way for the sustainable exploitation of HAAD.
The genome-wide sequence of Magnaporthe oryzae polymycovirus 1
Authors: Zheng Hong , Li Cong , Wang Yao , Ding Hang , An Hongliu , Fang Shouguo , Zhang Songbai , Deng Qingchao 
Published: January 2024

Abstract
A novel double-stranded RNA virus, designated as “Magnaporthe oryzae polymycovirus 1” (MoPmV-1), was identified in Magnaporthe oryzae strain TM02. MoPmV-1 has four dsRNA fragments, dsRNA 1 (2401bp), dsRNA 2 (2233bp), dsRNA 3 (1963bp) and dsRNA 4 (1324bp). Each dsRNA fragment contains one or two open reading frames, coding RNA-dependent RNA polymerase. Notably, the 5 '-terminal sequence and 3' -terminal sequence of these four dsRNAs are very similar to MoPmV-1, and homology searches and phylogenetic analyses indicate that this novel virus is closely related to the dsRNA viruses recently classified as Polymycoviridae.
Nickel-electrocatalyzed enantioselective C–H activations for chemo-divergence
Authors: Ackermann Lutz , von Münchow Tristan , Pandit Neeraj , Dana Suman , Boos Philipp , Peters Sven , Boucat Josselin , Liu Yi-Ru , Scheremetjew Alexej 
Published: January 2024

Abstract
Enantioselective electrocatalysis bears unique potential for the sustainable assembly of enantiomerically enriched molecules1–7. This approach allows electro-oxidative C–H activation to be performed paired to the hydrogen evolution reaction8,9. While recent progress featured scarce transition metals with limited availability10–17, we, herein, reveal that the Earth-abundant 3d transition-metal nickel is characterized by unique performance, while having high natural abundance18 and reduced toxicity19. Thereby, electrocatalytic C–H activation enabled enantioselective desymmetrizations with bicyclic alkenes, leading to three-dimensional molecular building blocks with multiple stereogenic elements20. Here, ligand optimization was guided by smart feature analysis for enantioselectivity enhancement. The detailed mechanistic investigation by experimental studies with organometallic intermediates in conjunction with computational studies identified key features of the ligand design including non-covalent interactions21,22 to guarantee full selectivity control.
The Faecal Microbiota of Captive Gyr Falcons Falco rusticolus (Linnaeus 1758) and Hybrids in the Kingdom of Saudi Arabia
Authors: Medammal Zubair , Surya Lysamma , Arif Ibrahim A , Al-Rasheed Mohammed , Al-Salem Abdulla M , Azeez PA 
Published: January 2024

Abstract
Falcons are traditionally used in falconry in the Kingdom of Saudi Arabia and many nations in the region. Many falcon species are kept captive and bred, selecting for their hunting capabilities in many of these countries. Of the several species of falcons, purebred Gyrfalcons (Falco rusticolus), the largest among falcons, is greatly appreciated by falconers for its hunting skill. Captive-bred Gyrfalcons can live, reproduce and hunt for long and are more stable. Aspergillosis is a non-contagious fungal disease of wild and domestic birds caused by fungus Aspergillus species. This fungal disease is economically important, being the main cause of mortality in captive birds, especially in falcons. This study assessed the effect of diet on the intestinal bacterial flora through faecal culturing of Aspergillosis-affected Gyrfalcons and discussed the potential of the isolated organisms as pathogens to spread to humans and avian species. An infected male Gyr and hybrid female (Gyr and Peregrine - F. peregrinus) were fed meat and a fresh chicken-rich diet for faecal samples, and the samples showed equal distribution of gram-positive and gram-negative bacteria relatively less harmful. The bacteria recovered here may be transient flora obtained through the diet and, under normal circumstances, may not actually be capable of colonizing and becoming permanent residents in the raptorial enteral tract. Thus, providing falcons with varied healthy diets is the best option in captivity, which could help falconers keep their birds free from infections.
Investigation of Non-alcoholic steatohepatitis development in newly designed short-term insulin resistance-fatty liver rat models. From chronic to acute
Authors: Mohammed Eman D. , Sun Beicheng 
Published: January 2024

Abstract

Background
The progression of insulin resistance (IR) and diabetes into non-alcoholic steatohepatitis (NASH) is a chronic process. The pathogenesis of diabetes progression into NASH is very complex and not fully understood. The lack of reproducible IR-NASH animal models that mimic human pathogenesis is the main roadblock. Therefore, we designed this study to investigate the development of IR-NASH within one month using new combinations of diets, fructose, and a small dose of streptozotocin (MFD or HFD/HFrD/STZ). And compare them with the known IR-NASH model using HFD/STZ.
Methods
Thirty-two male Wistar rats were randomized into four different groups and fed by either a different combination of diets or a chow diet for one month. After two weeks, a single dose of STZ was injected in all groups except the healthy group to develop diabetes. Body weights, animal mortality, eating, and drinking behaviors were recorded during the study. Glucose intolerance, hepatotoxicity indices, and fat accumulation were investigated. Also, we examined the hepatic histopathological alternations in rats.
Results
Animals’ body weights, eating, and drinking behaviors were extremely affected in high fructose diet (HFrD)-feed groups. Also, all groups showed a significant IR and glucose intolerance. However, the clear progressive NASH with aggressive hepatic steatosis, inflammation, and fibrosis was visualized in the investigated liver sections’ of HFrD-feed groups only. At the same time, the HFD/STZ group showed progressive non-alcoholic fatty liver disease (NAFLD) only.
Conclusion
MFD or HFD/ HFrD/ STZ models were successful short-term NASH models that can be used for pharmacological screening studies and dose selection. While HFD/STZ is a suitable model for chronic pharmacological investigations.
Evaluation of the Clinical, Biochemical, Genotype, and Prognosis of Propionic Acidemia in 133 Patients from China
Authors: Liang Lili , Hu Yuhui , Yu Yue , Ling Shiying , Qiu Wenjuan , Ye Jun , Zhang Huiwen , Lu Deyun , Gong Zhuwen , Zhan Xia , Ji Wenjun , Xu Feng , Liu Yuchao , Yu Yongguo , Gu Xuefan , Han Lianshu 
Published: January 2024

Abstract

Background Propionic acidemia (PA) is an inherited organic acid metabolic disease involving multiple physiological systems with variable manifestations. The causative genes,PCCAandPCCB, carry a wide range of mutations. The present study aimed to investigate the phenotype and genotype features of PA in Chinese patients. Methods We enrolled 133 PA patients who were treated during the past 17 years. We investigated their clinical data in detail, including national newborn screening (NBS) status and disease onset, biochemical metabolites, gene variations, and recent prognosis, to investigate the phenotype and genotype features. Results Among the 133 PA patients, 36 patients were diagnosed thanks to NBS expanded by tandem mass spectrometry (MS/MS). The median onset time was four months old, with symptoms involving multiple systems without specificity. The blood propionylcarnitine/ acetylcarnitine (C3/C2) ratio and urine 3-hydroxypropionic acid (3-OHPA) levels decreased after treatment. The overall prognosis of was poor, with 25.5% being healthy (34/133), 36.1% having developmental delays (48/133), 24.1% dying (32/133) and 14.3% being lost to follow-up (19/133). In thePCCAgene of 49 patients, 60 variants were detected, including 43 new variations. The variations c.2002G > A, c.229C > T, and c.1118T > A were the three most frequent variations. In thePCCBgene of 80 patients, 64 variants were detected, including 40 new variations. The variations c.1087T > C, c.838dup, and c.1228C > T were the three most frequent variations. Conclusion PA is a serious organic acidemia with early onset and nonspecific symptoms. The overall prognosis is poor. There are wide and relative common variations in Chinese patients in causative genes.
Abnormal characteristic static and dynamic functional network connectivity in fibromyalgia attention network
Authors: Wang Yingwei , Long Yingming , Xie Xinyan , Gao Ziyi , Fang Xiaokun , Xu Tong , Zhang Nan , Lv Dongling , Wu Ting 
Published: January 2024

Abstract
Background and purpose: Fibromyalgia is a commonly observed pain disorder linked to cognitive impairments, encompassing challenges in attention, memory, and executive processing. It has been proposed that fibromyalgia may be caused by changes in attention network. However, the neural network mechanisms underlying the relationship between the intrinsic fluctuations of functional connectivity in the brain network and clinical symptoms remain unclear.
Methods: 46 fibromyalgia patients and 36 healthy controls underwent resting-state functional MRI (rs-fMRI). We employed static functional network connectivity (sFNC) and dynamic functional network connectivity (dFNC) to investigate the potential relationship between alterations in sensory integration and attention networks in fibromyalgia and clinical features.
Results: Patients with fibromyalgia had reduced functional connectivity within the visual network (VIN), the auditory network (AUN), the default mode network (DMN), and the sensorimotor network (SMN). The decrease in functional connectivity in VIN and DMN was correlated with pain levels, while an increase in functional connectivity between SMN and the posterior dorsal attention network (DAN) was associated with symptoms. dFNC further observed that patients in state 4 show increased functional coupling between the ventral attention network (VAN) and both SMN and DMN, and the number of transitions between states positively correlated with pain levels.
Conclusion: dFNC offered additional insights for understanding the pathophysiological mechanisms underlying fibromyalgia. Fibromyalgia patients exhibited increased in the attention network and reduced functionality in visual and auditory networks, which might contribute to the diminished attention towards external environmental stimuli and heightened sensitivity self-perception sensations observed in fibromyalgia.
Early Pumping Behaviors Predict Pumped Milk Volume, Achievement of Secretory Activation and Coming to Volume in Breast Pump-Dependent Mothers of Preterm Infants
Authors: Median-Poeliniz Clarisa , Hoban Rebecca , Signorile Marisa , Janes Judy , Fan Steve , Meier Paula P. 
Published: January 2024

Abstract

Objective: Pumping studies in mothers of preterm infants are limited by self-reported pumping behaviors and non-objective measures of pumped milk volume and secretory activation (SA).
Study Design: Non-randomized observational study of first 14 days postpartum in 29 mothers of preterm infants. Smart pumps measured and stored pumping behaviors and pumped milk volume. Selective ion electrodes measured sodium and sodium:potassium ratio to determine SA. Generalized estimating equations, cluster analyses and multivariate regression were used.
Results: SA was delayed (median 5.8 days) and impermanent. Each additional daily pumping increased odds of SA within 2 days by 48% (p=.01). High-intensity pumping mothers (N=17) had greater daily and cumulative pumped milk volume than low-intensity pumping mothers (N=12). Pumping variables showed daily changes in the first week, then plateaued.
Conclusion: The first week postpartum is critical for optimizing pumping behaviors. Accurate, objective measures of pumping behaviors, pumped milk volume and SA are a research priority.