bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Peresepan Obat Metformin Dan Kombinasi Metformin - Glimepirid Antidiabetik Oral Di Rsud Sogaten Kota Madiun Periode Januari 2021 – Desember 2021
Authors: Kartikasari Utomo Grace 
Published: December 2023

Gambaran Peresepan Obat Antidiabetik Oral Di RSUD Sogaten Kota Madiun Periode Januari 2021 – Desember 2021

Diabetes Melitus adalah penyakit yang disebabkan oleh gangguan pada pankreas yang tidak dapat menghasilkan insulin sesuai dengan kebutuhan dalam tubuh dan ditandai dengan adanya banyaknya kadar glukosa darah (hiperglikemia). Penderita Diabetes Melitus dapat ditemukan di seluruh dunia dengan jumlah yang sangat berbeda pada setiap negara. Jumlah penderita diabetes melitus di Jawa Timur pada tahun 2019 sebanyak 841.994 kasus. Di RSUD Sogaten sendiri kasus Diabetes Melitus sebanyak 75 kasus
Jenis penelitian ini adalah kuantitatif dengan metode deskriptif dengan desain penelitian menggunakan prospektif. Populasi dalam penelitian ini yaitu sebesar 80 responden yang berada di Rawat Jalan dan rawat inap RSUD Sogaten Kota Madiun dengan total sampel seluruh populasi.
Hasil dari analisis data menunjukkan bahwa terdapat perbedaan yang signifikan antara penggunaan Antidiabetik Kombinasi dan tunggal yang di gunakan di RSUD Sogaten Kota Madiun adalah obat kombinasi Metformin – Glimepirid yang digunakan. Keberhasilan terapi untuk pasien tidak terlepas dari pemilihan obat yang tepat.
Dari hasil penelitian ini dapat disimpulkan bahwa Gambaran Peresepan Obat Antidiabetik Oral yang digunakan di RSUD Sogaten Kota Madiun adalah obat kombinasi metformin dengan glimepiride karena merupakan terapi kombinasi yang cukup efektif.

Kata Kunci : Diabetes Mellitus, Kombinasi Antidiabetik Metformin-Glimepirid.
Pratiques d’intervention à la protection de la jeunesse dans les situations de mauvais traitements psychologiques
Authors: Plante Nathalie 
Published: December 2023

L’intervention au sein des services de protection de la jeunesse (PJ) est influencée par différents discours et paradigmes d’intervention auxquels sont associées des injonctions qui peuvent ou non être en contradiction. Cet article vise à répondre à la question suivante : comment les personnes qui oeuvrent à la PJ font-elles face aux contradictions qui existent entre les différents discours qui influencent les pratiques dans les situations de mauvais traitements psychologiques ? Douze entrevues semi-dirigées ont été réalisées auprès des personnes oeuvrant aux différentes étapes de l’intervention de la PJ. Les résultats des analyses qualitatives montrent plusieurs contradictions entre le discours professionnel et les impératifs associés au discours légal et managérial. Plusieurs contradictions ont aussi été identifiées en lien avec le discours féministe dans les situations d’exposition à la violence conjugale. Nous nous penchons sur les modalités de coexistence des divers discours mis en oeuvre par les personnes rencontrées ainsi que sur leurs implications pratiques et théoriques. Nous discutons enfin des implications de l’impasse dialogique constatée entre les discours dominants, le discours professionnel et le discours féministe.
IoT Security in the Era of Ubiquitous Computing: A Multidisciplinary Approach to Addressing Vulnerabilities and Promoting Resilience
Authors: Olaniyi Oluwaseun Oladeji , Okunleye Olalekan Jamiu , Olabanji Samuel Oladiipo , Asonze Christopher Uzoma , Ajayi Samson Abidemi 
Published: December 2023

The Internet of Things (IoT) has rapidly become a pivotal, transformative force, seamlessly integrating billions of physical devices through sophisticated networks of embedded sensors, software, and internet connectivity. This expansive and interconnected ecosystem offers a broad spectrum of applications, significantly benefiting urban infrastructure with innovative solutions, enhancing industrial operations through optimization, and enriching consumer experiences with smart devices for safety and convenience. Despite the numerous benefits, the widespread adoption of IoT technologies has challenges, particularly in security and privacy. The proliferation of IoT devices has opened up new avenues for potential cyber threats, posing risks of data breaches and privacy violations. An in-depth analysis of notable IoT security incidents, such as the 2015 Jeep Hack, the Owlet WiFi Baby Heart Monitor Hack, and the TRENDnet Webcam Hack, highlights the critical vulnerabilities inherent in many IoT systems.
Organizations must adopt comprehensive and robust security measures to address these security concerns, including implementing advanced encryption protocols, deploying effective firewalls stringent access control mechanisms, and conducting regular security audits. A multi-layered security architecture becomes essential in mitigating such threats and ensuring the integrity of IoT networks. Furthermore, integrating blockchain technology presents a promising enhancement to IoT security and privacy protocols. Blockchain's inherent features of decentralization, transparency, and immutability offer an additional layer of security, making it more difficult for unauthorized entities to compromise IoT systems.
Equally crucial is the need to elevate IoT security awareness among organizations; this can be achieved through persistent research, fostering collaborations with security experts, and promoting best practices in IoT security. By actively addressing these security challenges, organizations can not only harness the full potential of IoT but also protect their reputations, build trust with stakeholders, and ensure the privacy and safety of their data. Therefore, while IoT presents an array of opportunities for innovation and efficiency, the importance of vigilance in security cannot be overstated. Balancing the benefits of IoT with robust security measures will be vital to realizing its full potential safely and reliably.
Effects of Various Indigenous Ripening Methods on Biochemical Characteristics of Banana Cv. Chenichampa
Authors: Roy Manuranjan , Hazarika Jahnabi , Timung Bamon , Basumatary Swgwmsar 
Published: December 2023

A study was conducted with objectives of how the native ripening technique affected the quality parameters of the Chenichampa variety of banana. The ripening techniques used during the period of experiment are as follows: T1 stands for ripening in a covered pit with smoke; T2 stands for ripening tomato fruit; T3 for ripening with paddy straw; T4 stands for ripening in a covered pit without smoke; T5 for ripening with calcium carbide; and T6, or naturally ripening at room temperature, which is the control. The outcome showed that, of all the ripening techniques, fruit ripened with ripe tomatoes maintained the lowest titratable acidity (0.23%), the maximum TSS (21.50%), and the reducing sugar (5.43%). Treatment T2 had the highest recorded moisture content (73.04%) and ash content (1.76%).
Effect of Integrated Nutrient Management on Seed Yield, Quality and Economics of Seed Production in Lucerne during Rabi Season
Authors: Desai Nagappa , Anitha M. S. , Shreenivasa K. R. , Patil Roopa B. 
Published: December 2023

The field experiment was conducted to study the effect of integrated nutrient management on seed yield, quality and economics of seed production in Lucerne (Medicago sativa L.) at the farm field of Krishi Vigyan Kendra, Konehalli, Tiptur taluk of Tumkuru district under southern dry zone of Karnataka during rabi seasons 2017-18. The experiments plots were laid out nine treatments with four replication and Randomized complete block design (RCBD). The results revealed that the maximum fresh herb yield at first harvest of herb (174.07 q/ha), herb yield after harvest of seeds (196.76 q/ha), early flowering (25.52 days), 50% flowering (33.45 days), pod initiation (46.90 days), pod maturation (71.68 days) were recorded during rabi seasons with application of 50 % RDF + 25 % N through vermicompost + Rhizobium + PSB + VAM. Whereas, minimum fresh herb yield, delayed flowering, pod initiation, pod maturation were recorded with application of 10 t/ha FYM + 100 % N through FYM.
The plants supplied with 50 % RDF + 25 % N through vermicompost + Rhizobium + PSB + VAM was resulted maximum pod set per cent (57.85 %), number of pods per plant (242.45), pod yield per plant (21.10), pod length (6.42 mm), pod weight (90.10 mg), seed set per cent (63.70 %), number of seeds per pod (5.68), test weight (3.36 g), seed yield (231.02 kg/ha) and highest net return per hectare during rabi season, while, least pod and seed characters, seed yield and net return per hectare were recorded with application of 10 t/ha FYM + 100 % N through FYM. Therefore, plants supplied with 50 % RDF + 25 % N through vermicompost + Rhizobium + PSB + VAM may be recommended for commercial seed production in Lucerne during rabi season under southern dry zone of Karnataka.
Assessing Pediatric Rheumatology Fellow Competence in the Milestone Era: Past, Present, and Future
Authors: Nowicki Katherine D. , Balboni Imelda M. , Cidon Michal J. , Dhanrajani Anita D. , Driest Kyla D. , Fair Danielle C. , Imundo Lisa F. , Mehta Jay J. , Tarvin Stacey E. , Walters Heather M. , Woolnough Leandra C. , Edgar Laura C. , Curran Megan L. 
Published: December 2023

Starting in 2015, pediatric rheumatology fellowship training programs were required by the Accreditation Council for Graduate Medical Education to assess fellows’ academic performance within 21 subcompetencies falling under six competency domains. Each subcompetency had four or five milestone levels describing developmental progression of knowledge and skill acquisition. Milestones were standardized across all pediatric subspecialties. As part of the Milestones 2.0 revision project, the Accreditation Council for Graduate Medical Education convened a workgroup in 2022 to write pediatric rheumatology‐specific milestones. Using adult rheumatology's Milestones 2.0 as a starting point, the workgroup revised the patient care and medical knowledge subcompetencies and milestones to reflect requirements and nuances of pediatric rheumatology care. Milestones within four remaining competency domains (professionalism, interpersonal and communication skills, practice‐based learning and improvement, and systems‐based practice) were standardized across all pediatric subspecialties, and therefore not revised. The workgroup created a supplemental guide with explanations of the intent of each subcompetency, 25 in total, and examples for each milestone level. The new milestones are an important step forward for competency‐based medical education in pediatric rheumatology. However, challenges remain. Milestone level assignment is meant to be informed by results of multiple assessment methods. The lack of pediatric rheumatology‐specific assessment tools typically result in clinical competency committees determining trainee milestone levels without such collated results as the foundation of their assessments. Although further advances in pediatric rheumatology fellowship competency‐based medical education are needed, Milestones 2.0 importantly establishes the first pediatric‐specific rheumatology Milestones to assess fellow performance during training and help measure readiness for independent practice.
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Chemoproteomics Reveals Glaucocalyxin A Induces Mitochondria‐Dependent Apoptosis of Leukemia Cells via Covalently Binding to VDAC1
Authors: An Yehai , Zhang Qian , Chen Yu , Xia Fei , Wong Yin‐Kwan , He Hengkai , Hao Mingjing , Tian Jiahang , Zhang Xiaoyong , Luo Piao , Wang Jigang 
Published: December 2023

AbstractChronic myelogenous leukemia (CML) that is resistant to tyrosine kinase inhibitors is one of the deadliest hematologic malignancies, and the T315I mutation in the breakpoint cluster region‐Abelson (BCR‐ABL) kinase domain is the most prominent point mutation responsible for imatinib resistance in CML. Glaucocalyxin A (GLA), a natural bioactive product derived from the Rabdosia rubescens plant, has strong anticancer activity. In this study, the effect and molecular mechanism of GLA on imatinib‐sensitive and imatinib‐resistant CML cells harboring T315I mutation via a combined deconvolution strategy of chemoproteomics and label‐free proteomics is investigated. The data demonstrated that GLA restrains proliferation and induces mitochondria‐dependent apoptosis in both imatinib‐sensitive and resistant CML cells. GLA covalently binds to the cysteine residues of mitochondrial voltage‐dependent anion channels (VDACs), resulting in mitochondrial damage and overflow of intracellular apoptotic factors, eventually leading to apoptosis. In addition, the combination of GLA with elastin, a mitochondrial channel VDAC2/3 inhibitor, enhances mitochondria‐dependent apoptosis in imatinib‐sensitive and ‐resistant CML cells, representing a promising therapeutic approach for leukemia treatment. Taken together, the results show that GLA induces mitochondria‐dependent apoptosis via covalently targeting VDACs in CML cells. GLA may thus be a candidate compound for the treatment of leukemia.
Half‐Valley Ohmic Contact: Contact‐Limited Valley‐Contrasting Current Injection
Authors: Feng Xukun , Lau Chit Siong , Liang Shi‐Jun , Lee Ching Hua , Yang Shengyuan A. , Ang Yee Sin 
Published: December 2023

AbstractThe 2D ferrovalley semiconductor (FVSC) with spontaneous valley polarization offers an exciting material platform for probing Berry phase physics. How FVSC can be incorporated in valleytronic device applications, however, remain an open question. Here, the concept of metal/semiconductor (MS) contact into the realm of valleytronics is generalized. A half‐valley Ohmic contact is proposed based on FVSC/graphene heterostructure, where the two valleys of FVSC separately forms Ohmic and Schottky contacts with those of graphene, thus allowing current to be valley‐selectively injected through the ‘Ohmic’ valley while being blocked in the ‘Schottky’ valley. A theory of contact‐limited valley‐contrasting current injection is developed and such transport mechanism can produce gate‐tunable valley‐polarized injection current. Using RuCl2/graphene heterostructure as an example, a device concept of valleytronic barristor is illustrated, where high valley polarization efficiency and sizable current on/off ratio, can be achieved under experimentally feasible electrostatic gating conditions. These findings uncover contact‐limited valley‐contrasting current injection as an efficient mechanism for valley polarization manipulation, and reveals the potential of valleytronic MS contact as a functional building block of valleytronic device technology.
Advances in Polymer Dielectrics with High Energy Storage Performance by Designing Electric Charge Trap Structures
Authors: Meng Zhaotong , Zhang Tiandong , Zhang Changhai , Shang Yanan , Lei Qingquan , Chi Qingguo 
Published: December 2023

AbstractDielectric capacitors have been developed for nearly a century, and all‐polymer film capacitors are currently the most popular. Much effort has been devoted to studying polymer dielectric capacitors and improving their capacitive performance, but their high conductivity and capacitance losses under high electric fields or elevated temperatures are still significant challenges. Although many review articles have reported various strategies to address these problems, to the best of current knowledge, no review article has summarized the recent progress in the high‐energy storage performance of polymer‐based dielectric films with electric charge trap structures. Therefore, this paper first reviews the charge trap characterization methods for polymeric dielectrics and discusses their strengths and weaknesses. The research progress on the design of charge trap structures in polymer dielectric films, including molecular chain optimization, organic doping, blending modification, inorganic doping, multilayered structures, and the mechanisms of the charge trap‐induced enhancement of the capacitive performance of polymers are systematically reviewed. Finally, a summary and outlook on the fundamental theory of charge trap regulation, performance characterization, numerical calculations, and engineering applications are presented. This review provides a valuable reference for improving the insulation and energy storage performance of dielectric capacitive films.
Spatially Dependent Optical Transmissivity of High Aspect Ratio Shape Memory Polymer Micropost Arrays with Tunable Angle
Authors: Xu Yuanhao , Leung Cheuk Wai , Pang Stella W. 
Published: December 2023

AbstractShape memory polymer (SMP) is a smart material that can memorize a permanent shape and, when exposed to a certain stimulus, recovers its original shape from a programmed temporary shape. High aspect‐ratio microposts are fabricated using deep reactive‐ion etching and thermal imprint, and are mechanically deformed to temporary bent morphologies. By applying a temperature gradient across this array of bent SMP microposts, they gradually recover at different speed to their original vertical position, starting from the heated end, resulting in a spatial dependence of bending recovery. The gradual recovery phenomenon is employed to illustrate the spatially dependent optical transmissivity of the micropost array, which exhibit different micropost angles. These findings provide evidence for the manipulation of optical transmission characteristics, encompassing diffraction, waveguiding, and depolarization, across various orientations. This high aspect ratio SMP micropost array is potentially useful for various optical devices and applications.
Highly Sensitive and Linear Vibration‐Based Flexible Modulus Sensing System for Human Modulus Monitoring and Disease Prevention
Authors: Luo Zewei , Shen Junhao , Ran Xu , Huang Zepeng , Huang Zaofeng , Wang Chaolun , Cai Chunhua , Lyv Liangjian , Lin Xin , Sun Litao , Chu Junhao , Bi Hengchang , Wu Xing 
Published: December 2023

AbstractIt is important to directly characterize the modulus of objects through wearable systems, which can further develop electronic skin and human‐computer interaction. In this work, a modulus sensing system based on a pressure sensor and vibration module is developed. This resistive pressure sensor exhibits good linearity and sensitivity. Combined with the vibration module to adjust the applied stress and strain, the modulus value of the objects can be directly calculated. The modulus sensing system demonstrates excellent modulus monitoring capabilities in the range of 60‒3000 kPa modulus and high linearity. In addition, it is used to detect modulus values for different parts of the human body and integrate a concept eye mask to prevent and monitor migraine. The system shows the potential to be further applied to wearable devices for human health monitoring and disease prevention.
Unveiled Influence of Sub‐gap Density of States on Low‐Frequency Noise in Si‐Doped ZnSnO TFTs: Does Correlated Mobility Fluctuation Model Suffice?
Authors: Shin Wonjun , Lee Ji Ye , Koo Ryun‐Han , Kim Jangsaeng , Lee Jong‐Ho , Lee Sang Yeol , Lee Sung‐Tae 
Published: December 2023

AbstractThe presence of low‐frequency noise (LFN) in amorphous oxide semiconductor (AOS) thin‐film transistors (TFTs) is of utmost concern, prompting extensive investigations into the analysis of LFN. However, prior research endeavors have tended to overlook the significance of the sub‐gap density of states (DOS) in the LFN analysis, resulting in an incomplete comprehension. To bridge this knowledge gap, the influence of sub‐gap DOS is demonstrated on LFN in Si‐doped ZnSnO (SZTO) thin‐film transistors (TFTs) under various conditions. The SZTO TFTs is intentionally subjected to positive bias stress and hot carrier stress in order to control the sub‐gap DOS and investigate how this change affects the LFN characteristics. It is revealed that the non‐uniform energetic distribution of sub‐gap DOS induces bias‐dependent excess noise in the SZTO TFTs. Additionally, self‐recovery behavior after the HCS is observed, accompanied by a commensurate reduction in 1/f noise. These empirical observations provide evidence that the conventional correlated mobility fluctuation model used to explain LFN in AOS TFTs is insufficient and underscores the critical importance of considering subgap DOS when analyzing LFN of AOS TFTs.
Water‐Soluble Inorganic Binders for Lithium‐Ion and Sodium‐Ion Batteries
Authors: Trivedi Shivam , Pamidi Venkat , Bautista Sebastian Pinto , Shamsudin Farra Nur Aliah , Weil Marcel , Barpanda Prabeer , Bresser Dominic , Fichtner Maximilian 
Published: December 2023

AbstractInorganic materials form an emerging class of water‐soluble binders for battery applications. Their favourable physicochemical properties, such as intrinsic ionic conductivity, high thermal stability (>1000 °C), and compatibility to coat a diverse range of electrode materials make them useful binders for lithium‐ion and sodium‐ion batteries. Li and Na containing phosphates and silicates are attractive choices as multifunctional inorganic aqueous binders (IABs). This review discusses these binders' structural, thermal, and ionic properties, followed by exploiting their ionically conducting nature for all‐solid‐state batteries. Subsequently, the application of these compounds as binders and surface coating agents for different anodes and cathodes in lithium‐ion and sodium‐ion batteries is discussed. Eventually, a first evaluation of their environmental impacts and economic aspects is presented as well.
Maternal age and adverse pregnancy outcomes among Meitei women of Manipur, Northeast India: A cross‐sectional study
Authors: Devi Thangjam Chitralekha , Singh Huidrom Suraj 
Published: December 2023

AbstractObjectiveThe study examines the outcomes of pregnancies conceived at advanced maternal age (AMA) and maternal complications after childbirth among Meitei women of Northeast India.MethodA total of 760 women participants were included in this study and compared among women aged ≥35 years, with a reference group of women aged 20–34 years. Data on obstetric characteristics were collected after obtaining consent. The data were compared using chi‐square analysis, and the results were adjusted using a logistic regression model. Decision trees were developed to predict the potential variables associated with preterm delivery and postpartum complication.ResultsIn the study, 18.95% of AMA women experienced one or more adverse pregnancy outcomes (APOs). Women with AMA are at significantly increased risk of placenta previa (adjusted odds ratio [AOR] = 4.89, 95% confidence interval [CI]: 2.78–8.57), induction of labor (AOR = 3.69, 95%CI: 2.48–5.50), and caesarean section (AOR = 3.42, 95%CI: 2.28–5.12). Moreover, AMA women have a 1.86–2.76 AOR for developing gestational diabetes, pregnancy‐induced hypertension, urinary tract infections, preterm delivery, and postpartum complications. Decision tree analysis revealed that AMA and urban residence independently predict preterm delivery and postpartum complications.ConclusionThe study's findings confirm the adverse impact of AMA on pregnancy outcomes and postpartum complications. Such issues should be addressed, and counseling on the risk of AMA should be provided, particularly for those in the high‐risk group. Further prospective studies are needed to understand other potential risk factors of APOs and the impact of AMA complications to prevent the associated burden.
Utility of a LangChain and OpenAI GPT‐powered chatbot based on the international consensus statement on allergy and rhinology: Rhinosinusitis
Authors: Workman Alan D. , Rathi Vinay K. , Lerner David K. , Palmer James N. , Adappa Nithin D. , Cohen Noam A. 
Published: December 2023

Key points
We created a LangChain/OpenAI API‐powered chatbot based solely on International Consensus Statement of Allergy and Rhinology: Rhinosinusitis (ICAR‐RS).
The ICAR‐RS chatbot is able to provide direct and actionable recommendations.
Utilization of consensus statements provides an opportunity for AI applications in healthcare.