bluuebunny/crossref_metadata_2025_split huggingface dataset:
Collaborative commerce or just common sense? Insights from vegetable supply chains in Ho Chi Minh City
Authors: Cadilhon Jean‐Joseph , Fearne Andrew P. , Thi Giac Tam Phan , Moustier Paule , Poole Nigel D. 
Published: July 2005

PurposeTo demonstrate that collaborative commerce is not restricted to trade in branded products between large, multi‐national organisations.Design/methodology/approachInsights from extensive field research in Viet Nam.FindingsThe benefits from collaborative commerce are plain for all to see yet very little of it is being practices in retail food chains at present, due primarily to incompatible organisational cultures and a competitive market environment that drives large corporations towards transactional relationships based on price competition. The insights from the Vietnamese vegetable supply chain demonstrate the simplicity of the principles of collaborative commerce and the ease with which they are adopted when the culture is conducive to collaboration and a partnership approach to trading relationships.Research limitations/implicationsFindings are based on research conducted in and around Ho Chi Minh city and on a narrow product range, but anecdotal evidence suggests the principles apply across all commodities and extend beyond the South of the country.Practical implicationsDemonstrates the importance of organisational culture in collaborative commerce, so businesses who wish to benefit from collaboration in the supply chain need to look at ways of developing an organisational culture that is conducive to collaboration.Originality/valueThis paper sheds new light on the application of the principles of collaborative commerce in a developing country context and in a low value‐high risk food category, without major investment in IT systems.
Stronger supply chain relationships: learning from research on strong families
Authors: Bullington Kimball E. , Bullington Stanley F. 
Published: July 2005

PurposeThe need for long‐term relationships between customer and supplier has been suggested for some time. The literature of supply chain management often compares customer‐supplier relationships to a marriage. The purpose of this paper is to apply results of research on successful families to supply chain management in order to improve these critical business relationships.Design/methodology/approachThe family strengths research is based on surveys and interviews of more than 6,000 successful families over a period exceeding 20 years, and has been summarized in six characteristics of successful families, which are used as the basis of a model of a successful supply chain relationship. The proposed model for successful supply chain relationships is then compared with the existing literature that addresses relationship success and failure.FindingsSupport for the characteristics in the supply chain relationships model was found in the literature. One weakness of the model was the failure to explicitly emphasize supplier performance.Originality/valueThe characteristics of principles‐centered relationships and the need for appreciation were new contributions. Generally, this aspect is not emphasized in the supply chain management literature. The supply chain relationships model provides a conceptual framework that should be useful in communicating the desired final state.
Improving chemical industry performance through enhanced railcar utilization
Authors: Closs David J. , Mollenkopf Diane A. , Keller Scott B. 
Published: July 2005

PurposeThe chemical industry is struggling to improve its supply chain performance, and improved asset utilization may help get the industry headed in the right direction. Since most chemical firms own or lease their rail fleets, rail utilization can have a substantial impact on overall asset utilization. The paper aims to focus on current managerial processes and situational factors that impact railcar asset performance.Design/methodology/approachRail car cycle data are analyzed, focusing on major sources of variation in transit inventory as railcars move from plant to customer and back.FindingsFindings include the importance of establishing and adhering to policies regarding supply chain practices; substantial differences exist between hopper and tank car performance; distance is not a major predictor of total cycle time variance; and vendor‐managed inventory relationships can operate with less customer inventory.Research limitations/implicationsThis paper addresses only one component of supply chain performance: railcar cycle time. Further analysis is needed to investigate differences between hopper car and tank car transit times. Additional research should also involve the railroad companies as participants in chemical firms' supply chains.Practical implicationsThe paper provides several practical recommendations for chemical company supply chain managers relating to process controls, focusing on large customer accounts, managing transit time and variation of rail cars between plant and factory. The findings and recommendations can be applied across many industries.Originality/valueThis paper focuses on supply chain practices in the chemical industry, which has been slow to adopt supply chain practices. In particular, this paper investigates railcar coordination as one means of enhancing supply chain performance, reducing both inventory and transportation assets.
The impact of decision‐making sharing between supplier and manufacturer on their collaboration performance
Authors: Kim Bowon , Oh Heungshik 
Published: July 2005

PurposeIThe purpose of this paper is to focus on manufacturers and suppliers who engage in strategic relationships for quality improvement and new product development. Depending on the balance of bargaining power in the relationship, each partner's resource commitment to the activities such as quality improvement and new product development may vary. This has implications for both manufacturer and supplier profitability. Therefore the paper aims to investigate how variations in the structure of the decision‐making process (i.e. manufacturer dominated, supplier dominated, or balanced) affect the performance of each partner in strategic collaborative relationship.Design/methodology/approachIn order to answer the research question, the paper uses real data from a telecommunications company to develop a simulation model and conduct a what‐if analysis.FindingsThe analysis shows that sharing the decision‐making process has indeed a significant impact on the collaboration performance: an optimal outcome would have been achieved should the objective function have taken into account both partners' profit maximization at the same time. Although the outcome may be bound by the specific context of the case, the paper puts forth that the supply chain partners could expect better performance from their collaboration when both of their perspectives are accommodated equally.Originality/valueIn conducting the research, unlike most of the previous studies using qualitative methods, this paper employed the system dynamics simulation to develop an analysis model by calibrating the real data. Therefore, the paper's conclusions are more analytical and generalizable than others based only on qualitative reasoning.
A competence‐based strategic management model factoring in key success factors and benchmarking
Authors: Chen Hsiu‐Li 
Published: July 2005

PurposeTo establish a comprehensive model of strategic management emphasized on the interactions of the organization with its external and internal environments and also to further develop a strategy based on competitive advantage.Design/methodology/approachBy using key success factor and benchmarking methodologies as well as Multi‐Dimensional Space technique, the operational customer's needs fall into four strategic cells: “anchoring”, “narrowing”, “following‐up”, and “catching‐up”, which can be improved in accordance with strategic moves.FindingsThe empirical study examines Taipei International Airport (TPE) and undertakes a comparison with its six major competitors in Asia. It has been found that Singapore as well as Hong Kong international airports prevailed over other competitors in the overall performance and thus were selected as the benchmarking airports. While the TPE outperforms the benchmarking airports in the Core Functional Area, it lags well behind in the Support Area. It is therefore strongly suggested that the TPE should develop its ability to build up Key Success Factors as well as to benchmark efficiently and effectively if it is to secure competitive advantage over the benchmarking airports.Originality/valueThe quantitative and strategic management model we built could help organizational members to analyze corporation's current position, to reach more competitive strategies, and to evaluate/change strategies effectively.
A business model for uncertainty management
Authors: Koh S.C.L. , Gunasekaran A. , Saad S.M. 
Published: July 2005

PurposeTo present the application of a business model for holistic uncertainty management for twenty‐first century manufacturing enterprises.Design/methodology/approachA questionnaire survey is carried out to UK manufacturing enterprises to collect relevant data, and analysis of variance (ANOVA), correlation analysis and cluster analysis are performed to infer the results.FindingsIt can be concluded that different manufacturing environments suffer different effects of underlying causes of uncertainty on product tardy delivery. The product tardy delivery performance in make‐to‐order (MTO) manufacturing environment is found significantly affected by a wide range of underlying causes of uncertainty. It is interesting to find that mixed‐mode (MM) manufacturing environment has an opposite outcome. Correlation results provide significant evidence that underlying causes of uncertainty do not have linear association with product tardy delivery. This finding reinforces the proposition that the effects of uncertainty are difficult to quantify due to the compound effect. The cluster analyses of the business environmental factors of the manufacturing enterprises in MM, make‐to‐stock (MTS) and MTO environments found that size of enterprise, product variety, product complexity, number of parts, ratio of buy vs make parts, the use of rough‐cut capacity planning, and the use of buffering or dampening techniques in production, influence the effects of underlying causes of uncertainty on product tardy delivery.Research limitations/implicationsOnly UK manufacturing enterprises are investigated. The results will be relevant to MTO, MM and MTS manufacturing environments.Practical implicationsThe application of the business model has provided useful knowledge to MM, MTS and MTO manufacturing enterprises on which underlying causes of uncertainty are significantly affecting their product tardy delivery performance.Originality/valueA holistic approach such as the business model has given a solid foundation for the enterprises to evaluate their performance. Using the knowledge of significant underlying causes of uncertainty, the enterprises could then prioritise the effort and devise suitable buffering or dampening techniques.
Engineering sustainable solutions program
Authors: Paten Cheryl J.K. , Palousis Nicholas , Hargroves Karlson , Smith Michael 
Published: July 2005

PurposeWhile a number of universities in Australia have embraced concepts such as project/problem‐based learning and design of innovative learning environments for engineering education, there has been a lack of national guidance on including sustainability as a “critical literacy” into all engineering streams. This paper was presented at the 2004 International Conference on Engineering Education in Sustainable Development (EESD) in Barcelona, Spain, outlining a current initiative that is seeking to address the “critical literacy” dilemma.Design/methodology/approachThe paper presents the positive steps taken by Australia's peak engineering body, the Institution of Engineers Australia (EA), in considering accreditation requirements for university engineering courses and its responsibility to ensure the inclusion of sustainability education material. It then describes a current initiative called the “Engineering Sustainable Solutions Program – Critical Literacies for Engineers Portfolio” (ESSP‐CL), which is being developed by The Natural Edge Project (TNEP) in partnership with EA and Unesco.FindingsContent for the module was gathered from around the world, drawing on research from the publication The Natural Advantage of Nations: Business Opportunities, Innovation, and Governance in the Twenty‐first Century. Parts of the first draft of the ESSP‐CL have been trialled at Griffith University, Queensland, Australia with first year environmental engineering students, in May 2004. Further trials are now proceeding with a number of other universities and organisations nationally and internationally.Practical implicationsIt is intended that ESSP‐CL will be a valuable resource to universities, professional development activities or other education facilities nationally and internationally.Originality/valueThis paper fulfils an identified information/resources need.
Influence of the N‐terminal domain on the aggregation properties of the prion protein
Authors: Frankenfield Kristen N. , Powers Evan T. , Kelly Jeffery W. 
Published: July 2005

AbstractPrion diseases appear to be caused by the aggregation of the cellular prion protein (PrPC) into an infectious form denoted PrPSc. The in vitro aggregation of the prion protein has been extensively investigated, yet many of these studies utilize truncated polypeptides. Because the C‐terminal portion of PrPSc is protease‐resistant and retains infectivity, it is assumed that studies on this fragment are most relevant. The full‐length protein can be distinguished from the truncated protein because it contains a largely structured, α‐helical, C‐terminal region in addition to an N terminus that is unstructured in the absence of metal ion binding. Herein, the in vitro aggregation of a truncated portion of the prion protein (PrP 90–231) and a full‐length version (PrP 23–231) were compared. In each case, concentration‐dependent aggregation was analyzed to discern whether it proceeds by a nucleation‐dependent pathway. Both protein constructs appear to aggregate via a nucleated polymerization with a small nucleus size, yet the later steps differ. The full‐length protein forms larger aggregates than the truncated protein, indicating that the N terminus may mediate higher‐order aggregation processes. In addition, the N terminus has an influence on the assembly state of PrP before aggregation begins, causing the full‐length protein to adopt several oligomeric forms in a neutral pH buffer. Our results emphasize the importance of studying the full‐length protein in addition to the truncated forms for in vitro aggregation studies in order to make valid hypotheses about the mechanisms of prion aggregation and the distribution of aggregates in vivo.
Crystal structure of the human vascular adhesion protein‐1: Unique structural features with functional implications
Authors: Airenne Tomi T. , Nymalm Yvonne , Kidron Heidi , Smith David J. , Pihlavisto Marjo , Salmi Marko , Jalkanen Sirpa , Johnson Mark S. , Salminen Tiina A. 
Published: July 2005

AbstractThe expression of human vascular adhesion protein‐1 (hVAP‐1) is induced at sites of inflammation where extravasation of lymphocytes from blood to the peripheral tissue occurs. We have solved the X‐ray structure of hVAP‐1, a human copper amine oxidase (CAO), which is distinguished from other CAOs in being membrane‐bound. The dimer structure reveals some intriguing features that may have fundamental roles in the adhesive and enzymatic functions of hVAP‐1, especially regarding the role of hVAP‐1 in inflammation, lymphocyte attachment, and signaling. Firstly, Leu469 at the substrate channel may play a key role in controlling the substrate entry; depending on its conformation, it either blocks or gives access to the active site. Secondly, sugar units are clearly observed at two of the six predicted N‐glycosylation sites. Moreover, mutagenesis analysis showed that all of the predicted sites were glycosylated in the protein used for crystallization. Thirdly, the existence of a solvent‐exposed RGD motif at the entrance to each active site in hVAP‐1 suggests that it may have a functional role.
HCA and HML isolated from the red marine algae Hypnea cervicornis and Hypnea musciformis define a novel lectin family
Authors: Nagano Celso S. , Debray Henri , Nascimento Kyria S. , Pinto Vicente P.T. , Cavada Benildo S. , Saker‐Sampaio Silvana , Farias Wladimir R.L. , Sampaio Alexandre H. , Calvete Juan J. 
Published: July 2005

AbstractHCA and HML represent lectins isolated from the red marine algae Hypnea cervicornis and Hypnea musciformis, respectively. Hemagglutination inhibition assays suggest that HML binds GalNAc/Gal substituted with a neutral sugar through 1–3, 1–4, or 1–2 linkages in O‐linked mucin‐type glycans, and Fuc(α1–6)GlcNAc of N‐linked glycoproteins. The specificity of HCA includes the epitopes recognized by HML, although the glycoproteins inhibited distinctly HML and HCA. The agglutinating activity of HCA was inhibited by GalNAc, highlighting the different fine sugar epitope‐recognizing specificity of each algal lectin. The primary structures of HCA (9193±3 Da) and HML (9357±1 Da) were determined by Edman degradation and tandem mass spectrometry of the N‐terminally blocked fragments. Both lectins consist of a mixture of a 90‐residue polypeptide containing seven intrachain disulfide bonds and two disulfide‐bonded subunits generated by cleavage at the bond T50–E51 (HCA) and R50–E51 (HML). The amino acid sequences of HCA and HML display 55% sequence identity (80% similarity) between themselves, but do not show discernible sequence and cysteine spacing pattern similarities with any other known protein structure, indicating that HCA and HML belong to a novel lectin family. Alignment of the amino acid sequence of the two lectins revealed the existence of internal domain duplication, with residues 1–47 and 48–90 corresponding to the N‐ and C‐terminal domains, respectively. The six conserved cysteines in each domain may form three intrachain cysteine linkages, and the unique cysteine residues of the N‐terminal (Cys46) and the C‐terminal (Cys71) domains may form an intersubunit disulfide bond.
Soluble domains of telomerase reverse transcriptase identified by high‐throughput screening
Authors: Jacobs Steven A. , Podell Elaine R. , Wuttke Deborah S. , Cech Thomas R. 
Published: July 2005

AbstractTelomerase is a ribonucleoprotein complex responsible for extending the ends of eukaryotic chromosomes. Structural and biophysical studies of this enzyme have been limited by the inability to produce large amounts of recombinant protein. Here we perform a high‐throughput screen to map regions of the Tetrahymena thermophila TERT (Telomerase Reverse Transcriptase) protein that are overexpressed in a soluble form in Escherichia coli using a GFP‐fusion system. Many of the soluble protein domains identified do not coincide with domains inferred from multiple sequence alignment, so screening for fluorescent colonies provided information not otherwise readily obtained. The method revealed an essential, independently folded N‐terminal domain that was expressed and purified with high yield and found to be suitable for structural analysis. These results provide a tool for future structural and biophysical studies of TERT.
Overexpression of Fos‐related antigen‐1 in head and neck squamous cell carcinoma
Authors: Mangone Flavia R. R. , Brentani M. Mitzi , Nonogaki Suely , Begnami Maria Dirlei F. S. , Campos Antonio Hugo J. F. M. , Walder Fernando , Carvalho Marcos B. , Soares Fernando A. , Torloni Humberto , Kowalski Luiz P. , Federico Miriam H. H. 
Published: July 2005

SummaryThe activating protein‐1 (AP‐1) family of transcription factors has been implicated in the control of proliferation and differentiation of keratinocytes, but its role in malignant transformation is not clear. The aim of this study is to assess the pattern of mRNA expression of jun‐fos AP‐1 family members in 45 samples of head and neck squamous cell carcinomas (HNSCC) and matched adjacent mucosa by means of Northern blot analysis. Transcripts of all family members were identified, except for JunB that was detected only by means of reverse transcription polymerase chain reaction. Neither c‐Fos nor JunD or FosB mRNA differed between tumours and normal tissues. We observed a strong Fos‐related antigen‐1 (Fra‐1) and Fra‐2 expression, but only Fra‐1 mRNA densitometric values were higher in tumour, compared to normal adjacent mucosa (t‐test, P = 0.006). A direct relationship between the positive expression of Fra‐1 mRNA, above tumour median, was associated with the presence of compromised lymph nodes (Fischer exact test, P = 0.006). In addition, Fra‐1 protein staining was assessed in a collection of 180 tumours and 29 histologically normal samples adjacent to tumours in a tissue array. Weak reactivity, restricted to the basal cell layer, was detected in 79% of tumour adjacent normal tissues, opposed to the intense reactivity of cancer tissues. In the subgroup of oral cancers, we have observed a shift in Fra‐1 immunoreactivity, as long as the number of patients in each category, cytoplasmic or nuclear/cytoplasmic staining, was analysed (Fischer exact test, P = 0.0005). Thus, Fra‐1 gene induction and accumulation of Fra‐1 protein may contribute to the neoplastic phenotype in HNSCC.
Hyperproduction of fibrin and inefficacy of antithrombin III and α2 macroglobulin in the presence of bacterial porins
Authors: Di Micco Biagio , Di Micco Pierpaolo , Lepretti Marilena , Stiuso Paola , Donnarumma Giovanna , Iovene Maria R. , Capasso Rita , Tufano Maria A. 
Published: July 2005

SummaryBacterial porins enhance the thrombin activity upon chromogen substrate chromozym. Should porin‐dependent enhancement of thrombin activity take place also upon fibrinogen in vivo, this might greatly increase the fibrin production which, in turn, might lead to blood vessel obstruction. In this study, we demonstrate fibrin hyperproduction in a simplified coagulative system, consisting of fibrinogen and thrombin‐pure molecules, in the presence of bacterial porins. In particular, bacterial porins, in the presence of thrombin, significantly increased the fibrin production compared with thrombin alone. Also, fibrin hyperproduction took place even in the presence of the thrombin inhibitors antithrombin III (AT III) or α2 macroglobulin (α2M). However, the thrombin–fibrinogen reaction in the presence of AT III or α2M did not generate fibrin, unless porins were present. In conclusion, porins not only enhance thrombin activity but also inhibit the antithrombin activity exerted by AT III or α2M. We hypothesize that, because of porins activity, fibrin is largely generated due to thrombin hyperactivation. Moreover, further fibrin is produced by thrombin, which is not blocked by two serpins for the presence of porins. These results might be relevant as to the occurrence of disseminated intravascular coagulation in sepsis by gram‐negative bacteria, which are known to produce porins.
Purchasing Portfolio Models: A Critique and Update
Authors: Gelderman Cees J. , Van Weele Arjan J. 
Published: July 2005

SummaryPurchasing portfolio models have spawned considerable discussion in the literature. Many advantages and disadvantages have been put forward, revealing considerable divergence in opinion on the merits of portfolio models. This study addresses the question of whether or not the use of purchasing portfolio models is considered as a sign of purchasing sophistication. Using data from a broad sample of industries, it was found that purchasing sophistication is a two‐dimensional construct: purchasing's professionalism and purchasing's position within companies. Results revealed that the position and the professionalism of purchasing are both positively related to the greater use of purchasing portfolio models. Findings indicate that portfolio usage is definitely a sign of purchasing sophistication.