bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bibliometric and visualized analysis of scientific publications on subglottic stenosis based on web of science core collection
Authors: Zhang Yaping , Dai Zhanqiu , Xia Qixin , Wu Yufeng , TingxiaoZhao  , Chen Qi , Xia Chen , Zhang Jun , Xu Jiongnan 
Published: February 2024

Abstract
Background
Subglottic Stenosis (SGS), with increasing numbers of studies, is the most specific and common clinical type of Laryngotracheal Stenosis (LTS). There is rapid publication turnover with newer management introduced and expanding research field. To our knowledge, there is no bibliometric analysis of SGS yet.

Methods
In August 2022, we performed a thorough search in the Web of Science Core Collection database using the word “subglottic stenosis,” and “SGS.” The 580 articles were arranged based on correlation. The collected articles were then analyzed with an assessment of relevant factors. Meanwhile, we analyzed the top 100 most-cited articles on SGS.

Results
The frequency of publication on SGS has increased substantially over time. The USA has contributed the most articles (n = 301). Vanderbilt University published most of the articles among other institutions (n = 18). Laryngoscope topped the list of journals and has published 89 SGS-related articles. Research hotspots shift from surgical treatment to conservative management.

Conclusions
The SGS-related literature has grown rapidly in recent years. This study represents the first bibliometric analysis of scientific articles on SGS. Areas to improve in SGS research can be identified after this analysis of the most impactful articles on this topic.
Atypical presentation of tight filum terminale with thoracic disc herniation: a case report
Authors: Miyagami Taiju , Nojiri Hidetoshi , Okada Satoru , Mitsumoto Kiichi , Uemura Kosuke , Naito Toshio 
Published: February 2024

Abstract
Background
Tight filum terminale is a rare and challenging condition to diagnose because it presents with nonspecific symptoms and unclear imaging findings. This report documents an atypical case of tight filum terminale.

Case presentation
The patient was a previously healthy Asian 18-year-old male presenting with recurrent upper extremity and back pain, initially treated as nonspecific musculoskeletal pain. Notably, the patient’s symptoms were inconsistent with the dermatome, showing no correlation with his skin’s sensory innervation areas. In contrast to typical tight filum terminale presentations focused on lower extremity and lumbar region disturbances, this patient experienced pain and weakness predominantly in the upper extremities and back, hypothesized to result from traction myelopathy exacerbated by thoracic disc herniation. Investigations including blood and nerve function tests were inconclusive. However, a magnetic resonance imaging scan revealed a combination of tight filum terminale and tiny thoracic disc herniation. A diagnosis of tethered spinal cord syndrome was confirmed following further tests and imaging. The filum terminale was surgically removed, resolving the symptoms at a 7-month follow-up.

Conclusions
This case underlines the importance of including tight filum terminale as a differential diagnosis in cases of unexplained upper or lower extremity pain. Primary care practitioners, particularly those managing undefined symptoms, should consider tight filum terminale in their diagnostic approach.
Exploring the impact of PEGylation on pharmacokinetics: a size-dependent effect of polyethylene glycol on prostate-specific membrane antigen inhibitors
Authors: Liu Yang , Xia Li , Li Haiyang , Cai Ping , Tang Sufan , Feng Yue , Liu Guangfu , Chen Yue , Liu Nan , Zhang Wei , Zhou Zhijun 
Published: February 2024

Abstract
Background
Prostate cancer is the second most frequent cancer and the fifth leading cause of cancer-related deaths in men. Prostate-specific membrane antigen (PSMA) as a target has gained increasing attention. This research aims to investigate and understand how altering size of PEG impacts the in vitro and in vivo behavior and performance of PSMA inhibitors, with a specific focus on their pharmacokinetic characteristics and targeting properties.

Results
Two 68Ga-labeled PSMA-targeted radiotracers were developed, namely [68Ga]Ga-PP4-WD and [68Ga]Ga-PP8-WD, with varying sizes of polyethylene glycol (PEG). [68Ga]Ga-PP4-WD and [68Ga]Ga-PP8-WD had excellent affinity for PSMA with IC50 being 8.06 ± 0.91, 6.13 ± 0.79 nM, respectively. Both tracers enabled clear visualization of LNCaP tumors in PET images with excellent tumor-to-background contrast. They also revealed highly efficient uptake and internalization into LNCaP cells, increasing over time. The biodistribution studies demonstrated that both radioligands exhibited significant and specific uptake into LNCaP tumors. Furthermore, they were rapidly cleared through the renal pathway, as evidenced by [68Ga]Ga-PP4-WD and [68Ga]Ga-PP8-WD showing a tenfold and a fivefold less in renal uptake, respectively, compared to [68Ga]Ga-Flu-1 in 30 min. Both in vitro and in vivo experiments demonstrated that PEG size significantly impacted tumor-targeting and pharmacokinetic properties.

Conclusions
These radiotracers have demonstrated their effectiveness in significantly reducing kidney uptake while maintaining the absorbed dose in tumors. Both radiotracers exhibited strong binding and internalization characteristics in vitro, displayed high specificity and affinity for PSMA in vivo.
Multiobjective trajectory optimization algorithms for solving multi-UAV-assisted mobile edge computing problem
Authors: Abdel-Basset Mohamed , Mohamed Reda , Hezam Ibrahim M. , Sallam Karam M. , Foul Abdelaziz , Hameed Ibrahim A. 
Published: February 2024

AbstractThe Internet of Things (IoT) devices are not able to execute resource-intensive tasks due to their limited storage and computing power. Therefore, Mobile edge computing (MEC) technology has recently been utilized to provide computing and storage capabilities to those devices, enabling them to execute these tasks with less energy consumption and low latency. However, the edge servers in the MEC network are located at fixed positions, which makes them unable to be adjusted according to the requirements of end users. As a result, unmanned aerial vehicles (UAVs) have recently been used to carry the load of these edge servers, making them mobile and capable of meeting the desired requirements for IoT devices. However, the trajectories of the UAVs need to be accurately planned in order to minimize energy consumption for both the IoT devices during data transmission and the UAVs during hovering time and mobility between halting points (HPs). The trajectory planning problem is a complicated optimization problem because it involves several factors that need to be taken into consideration. This problem is considered a multiobjective optimization problem since it requires simultaneous optimization of both the energy consumption of UAVs and that of IoT devices. However, existing algorithms in the literature for this problem have been based on converting it into a single objective, which may give preference to some objectives over others. Therefore, in this study, several multiobjective trajectory planning algorithms (MTPAs) based on various metaheuristic algorithms with variable population size and the Pareto optimality theory are presented. These algorithms aim to optimize both objectives simultaneously. Additionally, a novel mechanism called the cyclic selection mechanism (CSM) is proposed to manage the population size accurately, optimizing the number of HPs and the maximum function evaluations. Furthermore, the HPs estimated by each MTPA are associated with multiple UAVs using the k-means clustering algorithm. Then, a low-complexity greedy mechanism is used to generate the order of HPs assigned to each UAV, determining its trajectory. Several experiments are conducted to assess the effectiveness of the MTPAs with variable population size and cyclic selection mechanisms. The experimental findings demonstrate that the MTPAs with the cyclic selection mechanism outperform all competing algorithms, achieving better outcomes.
Potential types of bias when estimating causal effects in environmental research and how to interpret them
Authors: Konno Ko , Gibbons James , Lewis Ruth , Pullin Andrew S 
Published: February 2024

AbstractTo inform environmental policy and practice, researchers estimate effects of interventions/exposures by conducting primary research (e.g., impact evaluations) or secondary research (e.g., evidence reviews). If these estimates are derived from poorly conducted/reported research, then they could misinform policy and practice by providing biased estimates. Many types of bias have been described, especially in health and medical sciences. We aimed to map all types of bias from the literature that are relevant to estimating causal effects in the environmental sector. All the types of bias were initially identified by using the Catalogue of Bias (catalogofbias.org) and reviewing key publications (n = 11) that previously collated and described biases. We identified 121 (out of 206) types of bias that were relevant to estimating causal effects in the environmental sector. We provide a general interpretation of every relevant type of bias covered by seven risk-of-bias domains for primary research: risk of confounding biases; risk of post-intervention/exposure selection biases; risk of misclassified/mismeasured comparison biases; risk of performance biases; risk of detection biases; risk of outcome reporting biases; risk of outcome assessment biases, and four domains for secondary research: risk of searching biases; risk of screening biases; risk of study appraisal and data coding/extraction biases; risk of data synthesis biases. Our collation should help scientists and decision makers in the environmental sector be better aware of the nature of bias in estimation of causal effects. Future research is needed to formalise the definitions of the collated types of bias such as through decomposition using mathematical formulae.
Oils with different degree of saturation: effects on ileal digestibility of fat and corresponding additivity and bacterial community in growing pigs
Authors: Wang Lu , Chen Yifan , Yang Yuansen , Xiao Nuo , Lai Changhua 
Published: February 2024

Abstract
Background
Oils are important sources of energy in pig diets. The combination of oils with different degree of saturation contributes to improve the utilization efficiency of the mixed oils and may reduce the cost of oil supplemented. An experiment was conducted to evaluate the effects of oils with different degree of saturation on the fat digestibility and corresponding additivity and bacterial community in growing pigs.

Methods
Eighteen crossbred (Duroc × Landrace × Yorkshire) barrows (initial body weight: 29.3 ± 2.8 kg) were surgically fitted with a T-cannula in the distal ileum. The experimental diets included a fat-free basal diet and 5 oil-added diets. The 5 oil-added diets were formulated by adding 6% oil with different ratio of unsaturated to saturated fatty acids (U:S) to the basal diet. The 5 oils were palm oil (U:S = 1.2), canola oil (U:S = 12.0), and palm oil and canola oil were mixed in different proportions to prepare a combination of U:S of 2.5, 3.5 and 4.5, respectively.

Results
The apparent and standardized ileal digestibility (AID and SID) of fat and fatty acids increased linearly (P < 0.05) as the U:S of dietary oils increased except for SID of fat and C18:2. The AID and SID of fat and fatty acids differed among the dietary treatments (P < 0.05) except for SID of unsaturated fatty acids (UFA) and C18:2. Fitted one-slope broken-line analyses for the SID of fat, saturated fatty acids (SFA) and UFA indicated that the breakpoint for U:S of oil was 4.14 (R2 = 0.89, P < 0.01), 2.91 (R2 = 0.98, P < 0.01) and 3.84 (R2 = 0.85, P < 0.01), respectively. The determined SID of fat, C18:1, C18:2 and UFA in the mixtures was not different from the calculated SID of fat, C18:1, C18:2 and UFA. However, the determined SID of C16:0, C18:0 and SFA in the mixtures were greater than the calculated SID values (P < 0.05). The abundance of Romboutsia and Turicibacter in pigs fed diet containing palm oil was greater than that in rapeseed oil treatment group, and the two bacteria were negatively correlated with SID of C16:0, C18:0 and SFA (P < 0.05).

Conclusions
The optimal U:S for improving the utilization efficiency of mixed oil was 4.14. The SID of fat and UFA for palm oil and canola oil were additive in growing pigs, whereas the SID of SFA in the mixture of two oils was greater than the sum of the values of pure oils. Differences in fat digestibility caused by oils differing in degree of saturation has a significant impact on bacterial community in the foregut.
An analytical survey of zinc white historical and modern artists’ materials
Authors: Palladino Nicoletta , Occelli Mathilde , Wallez Gilles , Coquinot Yvan , Lemasson Quentin , Pichon Laurent , Stankic Slavica , Etgens Victor , Salvant Johanna 
Published: February 2024

Abstract
This study is the first systematic survey of a large corpus of zinc white (ZnO) artists’ materials. Zinc white is a white pigment developed within the wave of 19th-century technological developments in the paint industry. The composition, particle morphology and size, and luminescence of 49 zinc white samples from artists’ materials were characterized, including three references of known synthesis methods (indirect and direct) and synthesized by the authors (ZnO nanosmoke). The corpus included historical and modern zinc white pigment powders and paint materials from the leading European and American color manufacturers. The study aims to characterize and evaluate the variability of the properties of zinc white and its paint formulations. The reference materials presented properties in agreement with the literature: indirect ZnO exhibited submicron prismoidal blue-luminescent particles of higher purity than direct ZnO, which had larger acicular green-luminescent particles. ZnO nanosmoke presented acicular (tetrapod-like) blue/green-luminescent nanoparticles. Composition, particle morphology, size, and documentary sources suggested a production via the indirect method for the analyzed corpus. However, the luminescence behavior was more complex to interpret. The fundamental emission of ZnO was not always detected, even in pure ZnO powders. Three trends were identified: smaller ZnO particles for the most recent samples; green luminescence connected to larger particle size; fewer trace elements, and of the same type (i.e., lead, sulfur) for historical materials. Another interesting finding was the detection of hydrozincite in some powders, likely a degradation product of ZnO. In terms of methodology, cathodoluminescence proved a valuable tool for pigment identification. The study provides a database of zinc white references for pigment and artwork analysis.
Myopic choroidal neovascularization with neovascular signal around perforating scleral vessel prone to recur after anti-VEGF therapy
Authors: She Xiangjun , Yao Wangjing , Huang Gongyu , Liang Zhi , Xie Jin , Tao Jiwei , Wu Sulan , Mao Jianbo , Chen Yiqi , Zhang Yun , Shen Lijun 
Published: February 2024

Abstract
Background
To compare the recurrence of myopic choroidal neovascularization (mCNV) based on the neovascular signal of mCNV around the perforating scleral vessel (PSV).

Methods
A consecutive series of naïve patients with mCNV accepted anti-VEGF therapy with a minimum 12-month follow-up period. The neovascular signal relationship between PSV and mCNV were classified into the presence of neovascular signal of CNV around PSV or not. The recurrence of mCNV, best-corrected visual acuity (BCVA), hyperreflective foci height, CNV area and CNV flow area were analyzed between two groups.

Results
Neovascular signal of CNV around PSV was detected in 20 eyes (39.2%). The one-year recurrence rate in the group with neovascular signal of CNV around PSV was significantly higher than that in the group without neovascular signal of CNV around PSV (P = 0.045). The recurrence time in the group with neovascular signal around PSV was shorter than that in the group without neovascular signal around PSV (P = 0.030). Cox proportional hazard model showed that the presence of neovascular signal of CNV around PSV [hazard ratio (HR): 2.904] and subfoveal choroidal thickness ≤ 50 μm (HR: 0.368) were risk factors for recurrence of mCNV. In the group with neovascular signal around PSV, the BCVA was worse (P = 0.024) and the CNV flow area was more unstable (P = 0.027) after therapy.

Conclusions
PSV was commonly detected in patients with mCNV. The presence of neovascular signal of CNV around PSV was prone to recur with a shorter time in mCNV patients.
Evaluation of the accuracy of fully guided implant placement by undergraduate students and postgraduate dentists: a comparative prospective clinical study
Authors: Atay Ece , Hey Jeremias , Beuer Florian , Böse Mats Wernfried Heinrich , Schweyen Ramona 
Published: February 2024

Abstract
Purpose
This study aimed to assess the accuracy of implant placement through three-dimensional planning and fully guided insertion, comparing outcomes between undergraduate and postgraduate surgeons.

Methods
Thirty-eight patients requiring 42 implants in posterior single-tooth gaps were enrolled from the University Clinic for Prosthodontics at the Martin Luther University Halle Wittenberg and the Department of Prosthodontics, Geriatric Dentistry, and Craniomandibular Disorders of Charité University Medicine, Berlin. Twenty-two implants were placed by undergraduate students (n = 18), while 20 implants were placed by trainee postgraduate dentists (n = 5). Pre-operative intraoral scans and cone beam computed tomography images were performed for implant planning and surgical template fabrication. Postoperative intraoral scans were superimposed onto the original scans to analyze implant accuracy in terms of apical, coronal, and angular deviations, as well as vertical discrepancies.

Results
In the student group, two implant insertions were performed by the assistant dentist because of intraoperative complications and, thus, were excluded from further analysis. For the remaining implants, no statistically significant differences were observed between the dentist and student groups in terms of apical (p = 0.245), coronal (p = 0.745), or angular (p = 0.185) implant deviations, as well as vertical discrepancies (p = 0.433).

Conclusions
This study confirms the viability of fully guided implant placement by undergraduate students, with comparable accuracy to postgraduate dentists. Integration into dental education can prepare students for implant procedures, expanding access and potentially reducing costs in clinical practice. Collaboration is essential for safe implementation, and future research should explore long-term outcomes and patient perspectives, contributing to the advancement of dental education and practice.
Trial registration: DRKS, DRKS00023024, Registered 8 September 2020—Retrospectively registered, https://drks.de/search/de/trial/DRKS00023024.
Ameliorative role of diets fortified with Artocarpus altilis in a Drosophila melanogaster model of aluminum chloride-induced neurotoxicity
Authors: Saliu Jamiyu Ayodeji , Olajuyin Ayobami Matthew , Olowolayemo Samuel Faith 
Published: February 2024

Abstract
Backgrounds:
Artocarpus altilis (breadfruit) belongs to the family Moraceae. Artocarpus altilis possesses antioxidative, anti-inflammatory, and anti-proliferative properties. Aluminum (Al) is extensively utilized for consumer products, cooking utensils, pharmaceuticals, and industries. Indication for the neurotoxicity of Al is investigated in various studies, notwithstanding the precise mechanisms of Al toxicity are yet to be fully elucidated, and, which requires novel therapy. In this study, we determined the ameliorative role of Artocarpus altilis on aluminum chloride-induced neurotoxicity in Drosophila melanogaster.

Methods
Varying concentration of the extract were used to formulate diets for 6 groups of flies. Group 1 contained basal diet, group 2 contained basal diet and aluminium chloride (AlCl3), group 3 contained basal diet + 0.1% unseeded breadfruit (UBF), group 4 contained basal diet + 1% unseeded breadfruit, group 5 and 6 contained basal diet + AlCl3 + 0.1% and 1% unseeded breadfruit. Assays such as acetylcholinesterase activity, malondialdehyde (MDA) concentration level, catalase activity, and superoxide dismutase (SOD) activity were carried out after 7 days of exposure respectively.

Results
The results showed low activity of acetylcholinesterase activity and MDA level and high catalase and SOD activity in the pretreated and post-treated flies with Artocarpus altilis compared to the normal and negative control respectively.

Conclusions
Taken together, Artocarpus altilis is a promising prophylactic, antiacetylcholinesterase, and antioxidant plant in the prevention, management and treatment of neurodegenerative diseases.

Graphical Abstract
The effects of the COVID-19 pandemic on violations of the right to integrity of the person
Authors: Carraro Valentina 
Published: February 2024

AbstractThe ongoing COVID-19 pandemic has been having a devastating impact on society not only from a health and economic perspective but also due to its direct and indirect effects on the human rights of citizens. In particular, the pandemic has had several negative effects on citizens’ right to integrity. For example, lockdown measures adopted by governments to manage the pandemic frequently resulted in increased levels of violence against women and girls; so much so that the UN body working on gender equality (UN Women) coined a new term—‘shadow pandemic’—to refer to the severe intensification of all forms of violence against women and girls that occurred during the pandemic, particularly domestic violence. In addition, in some cases, police officials have employed disproportionate force to ensure strict adherence to public health measures. Finally, hate crimes against individuals of Asian origin or descent have increased substantially in Western countries. However, and perhaps more surprisingly, there have been situations in which the pandemic, directly or indirectly, has seemingly led to a decrease in specific forms of violence. Researchers have, for instance, observed that at the height of the pandemic, there has been a decrease in reported cases of street violence against women, because of fewer people leaving their homes.Based on document analysis and a review of selected country case studies, this article aims to provide a thorough overview of the different types of violations of the right to integrity of the person that have emerged, worsened, or, possibly, decreased as a direct or indirect consequence of the COVID-19 pandemic. It focuses on three key types of violations: domestic violence, violence against women in public spaces, excessive use of force by law enforcement agents, and racial violence against individuals of Asian origin or descent. The article starts by introducing the right to integrity of the person and then focuses on the different forms of integrity rights violations that have emerged as a direct or indirect consequence of the pandemic. It concludes by reflecting on lessons learned and by providing some evidence-based recommendations on possible rights-infringement mitigation strategies during public health crises.