bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presión positiva continua de la vía aérea en recién nacidos del Hospital General Sancti Spiritus
Authors: Gandoy Álvarez Diana Caridad , Ibarra Fiallo Yunior , González Méndez Adrian , Regalado López Rusanna Maydelis , López Fuentes Manuel Ramón 
Published: January 2024

Introducción: durante los últimos 5 a 10 años, el uso de del dispositivo de CPAP ha aumentado drásticamente. Se considera que la ventilación mecánica y la CPAP nasal son soportes eficaces en el Síndrome de Distrés Respiratorio, con el uso del surfactante; este último tan involucrado en la adaptación pulmonar a la vida extrauterina, previniendo de esa manera la atelectasia. Objetivo: evaluar la respuesta de los recién nacidos con distrees respiratorio y el reclutamiento alveolar ante la ventilación con presión positiva continua de las vías respiratorias en el Hospital Camilo Cienfuegos. Método: Se realizó un estudio observacional descriptivo transversal, en el Hospital General Provincial Camilo Cienfuegos de la Provincia de Sancti Spiritus, en el periodo comprendido de abril 2019 a abril 2020. Resultados: la mayoría de los neonatos con distrees respiratorio fueron del sexo masculino, se pudo determinar que el 45,45% casos nació con pesos suficientes de 3 001 gramos o más y que para el 95,45% casos de los pacientes el método ventilatorio no invasivo fue exitoso. Conclusiones: la Presión Positiva vía Aérea Continua es una forma segura y útil que debe ser empleado en los neonatos prematuros con dificultad respiratoria, para disminuir la incidencia de complicaciones.
Colapso en el Cuidador Primario del Paciente con Enfermedad Renal Crónica en Tratamiento Sustitutivo de la Función Renal
Authors: Luna Ramírez Paola Jacqueline , Urbina Aranda Irasema Isabel 
Published: January 2024

Los pacientes con enfermedad renal crónica en tratamiento sustitutivo de la función renal, necesitan cuidados complejos, requiriendo de un cuidador primario; a mayor dependencia, mayor es el grado de sobrecarga para el cuidador, quien puede llegar a presentar alteraciones físicas, emocionales y sociales, lo cual repercuten negativamente en la calidad de vida del cuidador y del paciente. Se identificó el colapso en el cuidador primario del paciente con enfermedad renal crónica en tratamiento sustitutivo de la función renal adscritos a la Unidad de Medicina Familiar no.9 Acapulco, Guerrero. La presente investigación se hizo mediante un estudio transversal analítico en 143 cuidadores primarios de pacientes con enfermedad renal crónica en tratamiento sustitutivo de la función renal en Acapulco, Guerrero, de diciembre a abril 2023, se aplicó la escala de Zarit para identificar el colapso del cuidador, el análisis estadístico se realizó con el programa SSPS, a través de análisis bivariado, obteniendo valor de p, OR e IC 95%.En los resultados se encontró que el 46% (66/143) de los cuidadores presenta colapso. El 62% (41/66), cursa con colapso intenso, mientras que el 38%(25/66) se encuentra con leve. El factor asociado con la presencia de colapso es el género femenino (p 0.005). Se concluyó que 5 de cada 10 cuidadores presentan colapso, de cada 10 cuidadores con colapso 6 de ellos cursa con colapso intenso y 4 con leve.
Post-Newtonian Orbital Effects Induced by the Mass Quadrupole and Spin Octupole Moments of an Axisymmetric Body
Authors: Iorio Lorenzo 
Published: January 2024

Abstract
The post-Newtonian orbital effects induced by the mass quadrupole and spin octupole moments of an isolated, oblate spheroid of constant density that is rigidly and uniformly rotating on the motion of a test particle are analytically worked out for an arbitrary orbital configuration and without any preferred orientation of the body’s spin axis. The resulting expressions are specialized to the cases of (a) equatorial and (b) polar orbits. The opportunity offered by a hypothetical new spacecraft moving around Jupiter along a Juno-like highly elliptical, polar orbit to measure them is preliminarily studied. Although more difficult to be practically implemented, also the case of a less elliptical orbit is considered since it yields much larger figures for the relativistic effects of interest. The possibility of using the S-stars orbiting the supermassive black hole in Sgr A* at the Galactic Center as probes to potentially constrain some parameters of the predicted extended mass distribution surrounding the hole by means of the aforementioned orbital effects is briefly examined.
The Aemulus Project. VI. Emulation of Beyond-standard Galaxy Clustering Statistics to Improve Cosmological Constraints
Authors: Storey-Fisher Kate , Tinker Jeremy L. , Zhai Zhongxu , DeRose Joseph , Wechsler Risa H. , Banerjee Arka 
Published: January 2024

Abstract
There is untapped cosmological information in galaxy redshift surveys in the nonlinear regime. In this work, we use the Aemulus suite of cosmological N-body simulations to construct Gaussian process emulators of galaxy clustering statistics at small scales (0.1–50 h
−1 Mpc) in order to constrain cosmological and galaxy bias parameters. In addition to standard statistics—the projected correlation function w
p(r
p), the redshift-space monopole of the correlation function ξ
0(s), and the quadrupole ξ
2(s)—we emulate statistics that include information about the local environment, namely the underdensity probability function P
U(s) and the density-marked correlation function M(s). This extends the model of Aemulus III for redshift-space distortions by including new statistics sensitive to galaxy assembly bias. In recovery tests, we find that the beyond-standard statistics significantly increase the constraining power on cosmological parameters of interest: including P
U(s) and M(s) improves the precision of our constraints on Ωm by 27%, σ
8 by 19%, and the growth of structure parameter, f
σ
8, by 12% compared to standard statistics. We additionally find that scales below ∼6 h
−1 Mpc contain as much information as larger scales. The density-sensitive statistics also contribute to constraining halo occupation distribution parameters and a flexible environment-dependent assembly bias model, which is important for extracting the small-scale cosmological information as well as understanding the galaxy–halo connection. This analysis demonstrates the potential of emulating beyond-standard clustering statistics at small scales to constrain the growth of structure as a test of cosmic acceleration.
Medial Rectus Inferior Half Plication for the Treatment of Near Exotropia
Authors: Weatherby Thomas , Marsh Ian 
Published: January 2024

Purpose:
To report a relatively new surgical treatment for near exotropia called medial rectus inferior half plication.

Methods:
This was a retrospective analysis of the outcomes from a single surgeon performing a plication of the inferior half of the medial rectus muscle in 17 consecutive patients with near exotropia unresponsive to medial rectus bupivacaine injection.

Results:
Thirteen of 17 (76%) patients were asymptomatic after surgery with no diplopia for near fixation and with either a normal or slightly reduced prism fusion range enabling them to have comfortable binocular single vision. There was one minor surgical overcorrection with distance diplopia that disappeared within 2 weeks of surgery. Of the 4 of 17 (24%) patients who required further intervention, 3 required one further surgical procedure and 1 required an injection of bupivacaine into the contralateral medial rectus muscle to obtain a satisfactory alignment and control of symptoms. No patient needed more than two total operations.

Conclusions:
The data show medial rectus inferior plication can produce excellent outcomes with minimal risk of overcorrection.

[
J Pediatr Ophthalmol Strabismus
. 2024;61(3):219–222.]
La « démarche géodocumentaire ». Essai sur la fonction réflexive de la géographie sociale dans un monde médiatisé
Authors: Raoulx Benoît 
Published: January 2024

Dans cette contribution, nous proposons de définir une « démarche géodocumentaire » à partir des dimensions épistémologiques de la géographie sociale. Le film documentaire est conçu comme une méthode à part entière, qui permet de mettre en œuvre la fonction réflexive de la géographie sociale. Il associe recherche, intervention sociale et formation auprès de différents publics. Au-delà de la construction d’images audiovisuelles, la démarche géodocumentaire est l’expression d’une géographie incorporée, apte à interroger le monde contemporain.
Antibody Response to the Sneathia vaginalis Cytopathogenic Toxin A during Pregnancy
Authors: McCoy Zion T , Serrano Myrna G , Edupuganti Laahirie , Spaine Katherine M , Edwards David J , Buck Gregory A , Jefferson Kimberly K 
Published: January 2024

Abstract
Sneathia vaginalis is a Gram-negative vaginal species that is associated with pregnancy complications. It produces cytopathogenic toxin A (CptA), a pore-forming toxin. To determine whether CptA is expressed in vivo and to examine the mucosal Ab response to the toxin, we examined human midvaginal swab samples obtained during pregnancy for IgM, IgA, and IgG Abs with CptA affinity. This subcohort study included samples from 93 pregnant people. S. vaginalis relative abundance was available through 16S rRNA survey. There were 22 samples from pregnancies that resulted in preterm birth in which S. vaginalis relative abundance was &lt;0.005%, 22 samples from pregnancies that resulted in preterm birth with S. vaginalis ≥0.005%, 24 samples from pregnancies that resulted in term birth with S. vaginalis &lt;0.005%, and 25 samples from pregnancies that resulted in term birth with S. vaginalis ≥0.005%. IgM, IgA, and IgG with affinity for CptA were assessed by ELISA. The capacity for the samples to neutralize CptA was quantified by hemolysis assay. All three Ab isotypes were detectable within different subsets of the samples. There was no significant association between relative abundance of S. vaginalis and the presence of any Ab isotype. The majority of vaginal swab samples containing detectable levels of anti-CptA Abs neutralized the hemolytic activity of CptA, with the strongest correlation between IgA and neutralizing activity. These results demonstrate that S. vaginalis produces CptA in vivo and that CptA is recognized by the host immune defenses, resulting in the production of Abs with toxin-neutralizing ability.
A Predictive Model of Vaccine Reactogenicity Using Data from an In Vitro Human Innate Immunity Assay System
Authors: Pullen Robert H , Sassano Emily , Agrawal Pankaj , Escobar John , Chehtane Mounir , Schanen Brian , Drake Donald R , Luna Ernesto , Brennan Richard J 
Published: January 2024

Abstract
A primary concern in vaccine development is safety, particularly avoiding an excessive immune reaction in an otherwise healthy individual. An accurate prediction of vaccine reactogenicity using in vitro assays and computational models would facilitate screening and prioritization of novel candidates early in the vaccine development process. Using the modular in vitro immune construct model of human innate immunity, PBMCs from 40 healthy donors were treated with 10 different vaccines of varying reactogenicity profiles and then cell culture supernatants were analyzed via flow cytometry and a multichemokine/cytokine assay. Differential response profiles of innate activity and cell viability were observed in the system. In parallel, an extensive adverse event (AE) dataset for the vaccines was assembled from clinical trial data. A novel reactogenicity scoring framework accounting for the frequency and severity of local and systemic AEs was applied to the clinical data, and a machine learning approach was employed to predict the incidence of clinical AEs from the in vitro assay data. Biomarker analysis suggested that the relative levels of IL-1B, IL-6, IL-10, and CCL4 have higher predictive importance for AE risk. Predictive models were developed for local reactogenicity, systemic reactogenicity, and specific individual AEs. A forward-validation study was performed with a vaccine not used in model development, Trumenba (meningococcal group B vaccine). The clinically observed Trumenba local and systemic reactogenicity fell on the 26th and 93rd percentiles of the ranges predicted by the respective models. Models predicting specific AEs were less accurate. Our study presents a useful framework for the further development of vaccine reactogenicity predictive models.
Eating vegetables is not always a good advice. A case report and literature review of acquired methemoglobinemia
Authors: Vercelli Andrea , Nasone Irene , Pagani Laura , Dacrema Alessandro , Veneziani Alberto , Agosti Antonio , Poggiali Erika 
Published: January 2024

Methemoglobinemia (MET) is a life-threatening condition resulting from the development of methemoglobin (MetHb), which binds oxygen irreversibly, causing refractory hypoxia and so-called “functional anemia”. MET can be caused by hereditary or acquired processes. Acquired forms are the most common. Symptoms correlate with the MetHb level and range from cyanosis and dyspnea to dysrhythmias, metabolic acidosis, coma, and cardiac arrest. MetHb levels above 70% are fatal. Methylene blue (MB) is the specific antidote. In all cases, supportive treatment, including intravenous hydration, glucose correction, and oxygen supplementation, must be started immediately. Exchange transfusion has been used successfully to treat MET and may be appropriate in patients for whom MB is ineffective. We report the case of a 54-year-old woman who presented to our emergency department for the acute and sudden development of chest pain, shortness of breath, and severe cyanosis after drinking a significant amount of boiled courgette water. Arterial blood gas analysis revealed a MetHb level of 26%. She was treated immediately with MB, oxygen supplementation, and hydration with normalization of her MetHb in 12 hours. Our recommendation is to always investigate MET in patients with unexplained cyanosis and refractory hypoxia.
La transición agroecológica de los pequeños productores de huertos familiares
Authors: Castellanos-Guzmán Diana , Toledo-López Arcelia , Guzmán-Cruz Dora Lilia 
Published: January 2024

En este trabajo se describe el proceso de investigación acción participativa (IAP) en la comunidad de Cuilápam de Guerrero, Oaxaca, en un contexto de confinamiento causado por la pandemia de covid-19 (2021), situación que motivó el interés por la actividad agrícola y de traspatio en algunos habitantes. El objetivo de esta investigación fue generar alternativas agroalimentarias, a través de huertos familiares agroecológicos, para reducir la inseguridad alimentaria de las familias de pequeños productores agrícolas de subsistencia.
Se integró un grupo solidario de 10 participantes de 7 Unidades de Producción Familiar (UPF), interesados en la transición agroecológica para producir alimentos más sanos y saludables. Siguiendo la metodología IAP, se identificaron las necesidades de capacitación y se programaron los talleres con enfoque agroecológico. A través de este proceso, los participantes obtuvieron nuevos conocimientos para la práctica agrícola, intercambiaron saberes y establecieron valores dentro del grupo de trabajo como, la solidaridad, ayuda mutua, cooperación, reciprocidad y compromiso con el entorno.
Concept of Avapeeda Nasya in Shalakya Tantra
Authors: Rawat Sugandha  , Tiwari Ashish  , Ch.Ramadevi  , K. Anasuya  
Published: January 2024

Avapeeda nasya is a special procedure described to treat Urdhwajatrugata vikaras in Ayurveda. In this procedure fresh juice (Swarasa) is obtained by squeezing paste of herbs or decoction is used to instil in nostril. Shalakya is special branch of Ayurveda which deals with the diseases above clavicle (Jatru). Aiming for Vyadhi-parimokshana treatment can be done by Sanshamana or Sanshodhan methods. Panchakarma is Shodhana type in which Nasya is a procedure. Acharyas mentioned Nasa hi shirso dwaram, meaning it is the portal to head (for drug administration). To critically appraise and understand the standard Avapeeda Nasya is the focus of my presentation. Procedure of Avapeeda Nasya, its difference from Sneha nasya, mode of action and other norms are discussed in the paper.
Avapeeda Nasya acts as Shodhana and Shamana. When abundance of Doshas are present Tikshna dravyas are used to clear the channels (Sroto-Shodhana), when Doshas are mild or moderate Shamana dravyas are used. To expel Doshas from upper body, Nasa is the portal to Shiras. The active principle of the medicine used in Nasya reaches Shringataka marma (Sira marma) and is distributed to Moordha- Netra – Shrotra – Kantha and thereby expel morbid Doshas. Drug reaches the target area by crossing nasal mucosa, thereafter transported via nerve tract, systemic circulation or by lymphatics. Intra-nasally administered drug has higher bioavailability as it avoid first pass mechanism at liver and evade BBB.
ROLE OF RASAYANA CHIKITSA IN THE MANAGEMENT OF FEMALE INFERTILITY W.S.R. HYPOTHYROIDISM- A CASE STUDY
Authors: Gandham Neelima  , V.Narasimha  , A. Vijaya Lakshmi  
Published: January 2024

Ayurveda is the Ancient system of Medicine which gives equal importance to preventive and curative aspects of treatment. Rasayana Chikitsa plays a key role in the treatment of all the diseases (both in curative and preventive). There is nothing painful and stressful to women, for not being conceived. In the present modern era, female infertility is raised to the alarming extent due to diet & lifestyle modifications. Couples suffering from the infertility are approaching the infertility centres and going for the artificial reproductive techniques (IUI, IVF, ICSI-ET, Sarogasy). Ayurveda, through its unique line of treatment approaches, paves the way for fertility management through the medicines along with diet & lifestyle modifications. The Commonest cause for fertility being the Hypothyroidism in females (in this present study, I have considered hypothyroidism as Rasa pradosaja vyadi), clinical study was done at OPD, DR. BRKR Govt Ayurvedic College, Hyderabad and treated the patient with Dipana, Pachana, Rasayana Chikitsa and the patient conceived. In this present article an attempt is made to review and understand the concept of Rasayana chikitsa in the management of infertility with special reference to hypothyroidism (Dhatupradosja vyadi).
Psychological Well-Being and Job Satisfaction of Kenyan Police Officers
Authors: Ndero Peter , Kimamo Charles , Mwaura Lucas 
Published: January 2024

Purpose: Police work is a high risk job in terms of stress and low psychological wellbeing. In Kenya, police officers have presented high levels of suicide, homicide, assault and intimate partner abuse and this has become a matter of concern.
Methodology: This theoretical paper applies the hermeneutic phenomenological approach to study psychological wellbeing and job satisfaction of police officers as a phenomenon and how it affects police work. Extensive and systematic literature review is done using search engines like google scholar, web of science and Scopus. The search includes historical and contemporary scholarly data which reveals how police work is understood by scholars and the media. This data is then assessed and interpreted to discern the emerging patterns, findings and conclusions.
Findings: Statistics on the Kenya police service indicate that 20,000 police officers are either depressed or they present with various psychological disorders. Between 2016 and 2020 police have recorded within their ranks across the country 13 murders and 11 suicides per year without a break. Systematic literature view has revealed that high psychological wellbeing of police officers is imperative in order to remove or reduce psychological morbidity in police work. This not only decreases turnover, but also retains talent, and increases productivity. High psychological wellbeing also spills over to work teams and families in terms of happiness and wellbeing. Analysis of literature has also revealed that job satisfaction is one of the facets of psychological wellbeing at the work place.
Unique Contribution to Theory, Practice and Policy: This paper proposes that police managers, and stakeholders should proactively put in place strategies that enhance job satisfaction and therefore improve the psychological wellbeing of police officers. Researchers in partnership with police management should also address the knowledge gap in explaining how police stressors finally precipitate the high rates of murders and suicide and implement solutions.
ANALISA KORELASI TEMPERATUR AIR TERHADAP WAKTU PADA SAAT PEMANASAN DAN PENDINGINAN MENGGUNAKAN BAHAN BAKAR GAS DENGAN TEKANAN KONSTAN 5 BAR DAN BUKAAN VALVE GAS 25%
Authors: Siagian Tony 
Published: January 2024

Panas yang diberikan terhadap suatu fluida akan menyebabkan kenaikan temperatur pada fluda tersebut melalui perpindahan panas dari sumber pemanas melalui rambatan panas radiasi, konveksi dan koduksi sampai ke objek fluida yang dipanaskan. Dalam hal ini air sebagai bahan penelitian yang ditampung dalam suatu wadah stainless stell kapasitas 1000 ml. Berdasarkan penelitian ini diperoleh bahwa pada posisi pemanasan dengan waktu 10 menit terjadi kenaikan temperature paling tinggi yaitu 94.8 OC dan berikutnya terjadi stagnasi kenaikan temperatur dan mengalami sedikit penurunan temperatur walapun tetap dilakukan pemanasan terhadap air dan pada saat pendinginan dijumpai secara konsisten terjadi penurunan temperatur air dengan penurunan temperatur tertinggi terjadi pada titik waktu pendinginan 0 sampai 2 menit dengan besarnya perbedaan penuruan temperatur 14.5 OC dan untuk koefisien korelasi didapatkan nilai tertinggi pada proses pendinginan rxy = -0.9374 (Korelasi negatif) yang dibanding dengan Koefisien korelasi untuk proses pemanasan rxy = 0.8788 (Korelasi positif).
The heat given to a fluid will cause an increasing temperature of the fluid through heat transfer from the heating source through radiation, convection and coduction heat into the fluid object being heated, In this case water as materil for reasearch which is stored in a stainless steel container with a capacity of 1000 ml. Based on the research it was got that on heating position for 10 minutes found the highest temperature increasing occurred on 94.8 OC and then there was a stagnation in the temperature increasing and a slight decrease on temperature even though the water was still heated and during cooling it was found that the water temperature consistently decreased which is the highest temperature decrease occurred at the cooling time point of 0 to 2 minutes with a temperature decrease diffrenciate of 14.5 OC. Regarding to coefficient of correlation, the highest rate was found on the cooling process rxy = -0.9374 (negative correlation) that compared to the coefficient of correlation for the heating process rxy = 0.8788 (positive correlation) .
Analisis Pergeseran dan Pemertahanan Bahasa Pakpak Dialek Boang di Kecamatan Rundeng Kota Subulussalam
Authors: Herlinanto Herlinanto , Jumiati Resa 
Published: January 2024

Pergeseran dan pemertahanan bahasa Pakpak dialek Boang pada masyarakat merupakan kajian sosiolinguistik. Tujuan dari penelitian ini adalah mendeskripsikan pergeseran dan pemertahanan bahasa Pakpak dialek Boang di Desa Pasar Rundeng. Metode yang digunakan adalah metode deskriptif kualitatif. Sumber data penelitian ini masyarakat Desa Pasar Rundeng dengan kisaran umur 15-50 tahun. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah teknik observasi, rekam, simak, dokumentasi dan catat. Instrumen yang digunakan adalah lembar wawancara, dan lembar observasi. Teknik analisis data yang digunakan adalah pengumpulan data, reduksi data, penyajian data, penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa (1) pergeseran bahasa Pakpak dialek Boang di Desa Pasar Rundeng yang disebabkan oleh kedwibahasaan dan alih generasi; dan (2) pemertahanan bahasa Pakpak dialek Boang di Desa Pasar Rundeng di sebabkan dalam ranah kelurga dan ranah pergaulan