bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double jeopardy: FCPA enforcement and MNC risk-mitigation strategies
Authors: Xu Jian 
Published: January 2024

AbstractDoes transnational anti-bribery enforcement affect the risk-mitigation strategies of firms? This paper uses an original dataset on the enforcement actions of the Foreign Corrupt Practices Act (FCPA) to examine the law’s impact on corporate behavior and political risks for multinational corporations (MNCs). I argue that corrupt institutions are not necessarily undesirable for foreign investors. Foreign firms seek above-normal returns in high-risk markets through informal exchanges with the host government. FCPA enforcement provides a “fire alarm” that affects firms differently given their sensitivity to corruption concerns. FCPA enforcement has unequal deterrence against corporate misconduct, encouraging some firms to adopt transparency norms while incentivizing other firms to be more insidious in their corrupt business practices. I use a partial observability bivariate probit model to estimate the unobservable propensity of firms to engage in corrupt exchanges. Then I examine the impact of FCPA enforcement on Chinese FDI, and find that Chinese investments are deterred from markets with robust legal institutions. The FCPA’s deterrence effects against corrupt competitors is a positive outcome for U.S. MNCs. However, American companies experience diminished returns in countries with strong investor protection regimes. External legal interventions under the FCPA generate regulatory burdens on U.S. that limit their business opportunities.
Gender differences in life expectancy free of depressive symptoms in Chile between 2003 and 2016
Authors: Moreno Ximena , Monsalves María José , Rueda Sarahí , Dagnino Paula , Borghero Francesca 
Published: January 2024

Abstract
The aim of the study was to analyze gender differences in life expectancy free of depressive symptoms among the adult population in Chile between 2003 and 2016. The Sullivan method was used to estimate the total and marginal life expectancy, based on prevalence data from the National Health Survey (2003, 2010 and 2016), and abridged life tables for the Chilean population. There was a compression of morbidity among middle-aged men during the first period and among younger and older women during the last one. Men at all ages could expect to live a higher proportion of their lives without depressive symptoms during the whole period. The gender gap in the proportion of life expectancy free of depressive symptoms reached 10 percent points or more, considering almost all ages and periods. Unemployment and lower education increased the probability of depressive symptoms, and these effects were more marked among women. Public policies should have a gender-sensitive approach to address the gap in depression and the disadvantage experienced by women in life expectancy free of depressive symptoms, considering those dimensions that intersect with gender, such as access to education, employment or income.
14C IN TREE RINGS IN THE VICINITY OF THE RBMK REACTOR NUCLEAR POWER PLANT
Authors: Nazarov Evgeniy I , Kruzhalov Alexander V , Vasyanovich Maxim E , Ekidin Alexey A , Pyshkina Maria D , Kukarskikh Vladimir V , Parkhomchuk Ekaterina V 
Published: January 2024

ABSTRACTThe paper presents the results of radiocarbon (14C) concentration measurements in tree rings in the vicinity of Kursk NPP (Russia) with four operating RBMK reactors. The sampling was carried out from the site with the highest expected accumulation of radiocarbon in vegetation. The site was determined with long-term meteorological data. The measurements of 14C concentration carried out with accelerator-mass spectrometer in Budker Institute of Nuclear Physics, Novosibirsk, Russia. The obtained results demonstrated the influence of exploitation of Kursk NPP to the concentration of 14C in tree rings. Based on the equilibrium between the 14C ratio in the tree rings and the surrounding air, retrospective estimates of the radiocarbon discharge and effective doses were made. Effective doses were calculated with two approaches: IAEA methodology and less conservative approach, considering the real food consumption in the Kursk region. The values of calculated doses by the second method (0.08–2.58 μSv) are more than 2 times less than IAEA approach (0.17–5.30 μSv). The highest difference between measured and background 14C in tree ring is 41.7 ± 5.8 pMC in 2014 during the restoration of graphite stack. The main contribution to 14С exposure in the considering period is caused by background – from 70 to 99%.
Understanding Public Support for Policies Aimed at Gender Parity in Politics: A Cross-National Experimental Study
Authors: Carson Andrea , Gravelle Timothy B. , Acosta Rueda Lía , Ruppanner Leah 
Published: January 2024

Abstract
Across the globe, women are underrepresented in elected politics. The study's case countries of Australia (ranked 33), Canada (61) and the United States (66) rank poorly for women's political representation. Drawing on role strain and gender-mainstreaming theories and applying large-scale survey experiments, we examine public opinion on non-quota mechanisms to bolster women's political participation. The experimental design manipulates the politician's gender and level of government (federal/local) before asking about non-quota supports to help the politician. We find public support for policies aimed at lessening work–family role strain is higher for a woman politician; these include a pay raise, childcare subsidies and housework allowances. This support is amplified among women who are presented with a woman politician in our experiment, providing evidence of a gender-affinity effect. The study's findings contribute to scholarship on gender equality and point to gender-mainstreaming mechanisms to help mitigate the gender gap in politics.
Optimising cervical cancer screening during pregnancy: a study of liquid-based cytology and HPV DNA co-test
Authors: Gu Liying , Hu Yuan , Wei Yingting , Hong Zubei , Zhang Yu , Lin Jianhua , Qiu Lihua , Di Wen 
Published: January 2024

Abstract
This study assessed the efficacy of ThinPrep cytologic test and human papillomavirus (HPV) co-test in cervical cancer screening during pregnancy. A cohort of 8,712 pregnant women from Ren Ji Hospital participated in the study. Among them, 601 (6.90%) tested positive for high-risk HPV (HR-HPV) and 38 (0.44%) exhibited abnormal cytology results (ASCUS+). Following positive HR-HPV findings, 423 patients underwent colposcopy, and 114 individuals suspected of having high-grade squamous intraepithelial lesion and cervical cancer (HSIL+) underwent cervical biopsy. Histological examination revealed 60 cases of normal pathology (52.63%), 35 cases of low‐grade squamous intraepithelial lesion (30.70%), 17 cases of HSIL (14.91%), and 2 cases of cervical cancer (1.75%). The incidence of HSIL+ in HPV 16/18 group was significantly higher than that in non-HPV16/18 group (10.53% vs. 6.14%, P < 0.05). Subsequent evaluation of the clinical performance of cytology alone, primary HPV screening, and co-testing for HSIL+ detection revealed that the HSIL+ detection rate was lowest with cytology alone. These findings suggest that HPV testing, either alone or combined with cytology, presents an efficient screening strategy for pregnant women, underscoring the potential for improved sensitivity in cervical cancer screening during pregnancy. The significantly higher incidence of HSIL+ in the HPV16/18 group emphasizes the importance of genotype-specific considerations.
Fostering English speaking and writing subskills for the Cambridge B2 First through technology-mediated tasks
Authors: Morgana Valentina 
Published: January 2024

AbstractRecent studies on technology-mediated task-based learning have shown the impact of task design and modality on English as a foreign language (EFL) learning. However, it is unclear what effect technology-mediated tasks have on learners’ English language skills. This paper presents a classroom-based study that showed how using technology-mediated tasks impacted students’ learning experiences and fostered the development of specific speaking and writing subskills in an EFL secondary education context. Forty-two EFL intermediate learners completed two speaking and two writing tasks from the Cambridge B2 First exam using mobile devices. The participants were divided into a pen-and-paper group (N = 21) and an iPad group (N = 21). Learning outcomes were measured using a pre-test/post-test design with a statistical comparison of ratings across tasks. A qualitative content analysis of lesson observations and student and teacher interviews served as an additional dataset to shed light on learners’ experiences. Descriptive statistics revealed that the iPad group achieved higher scores in pronunciation and accuracy (speaking) and essay organisation features (writing). Tasks involving the active use of the tool for content creation, rehearsing speaking performances, and accessing authentic materials were the most successful among students.
Learning to Use Trade Preferences: A Firm and Transaction Level Analysis of the EU–South Korea FTA
Authors: Kasteng Jonas , Kokko Ari , Norell Nils , Tingvall Patrik 
Published: January 2024

AbstractThis article examines imports by Swedish firms and the utilization of the tariff preferences offered by the EU–South Korea Free Trade Agreement. To benefit from tariff preferences, the importer must make a formal request to use the preferences and also document the origin of the imported products (with a certificate of origin provided by the foreign exporter). This may be costly, and some importers choose to pay import tariffs even when tariff preferences are available. Hence, the preferences are not fully utilized. Using a detailed firm–transaction level data set on Swedish imports from South Korea, we analyse the determinants of preference utilization and how firms learn to use preferences. The results show that preference utilization is strongly correlated with potential duty savings, which depend on the preference margin and the size of the import transaction. From a learning perspective, we find that preference utilization is closely related to the number of import transactions undertaken by the firm, suggesting a learning-by-doing mechanism. The length of time the firm has been involved in importing activities plays a smaller role.
A New Method to Invert for Interseismic Deep Slip Along Closely Spaced Faults Using Surface Velocities and Subsurface Stressing‐Rate Tensors
Authors: Elston H. , Cooke M. , Loveless J. , Marshall S. 
Published: January 2024

AbstractInversions of interseismic geodetic surface velocities often cannot uniquely resolve the three‐dimensional slip‐rate distribution along closely spaced faults. Microseismic focal mechanisms reveal stress information at depth and may provide additional constraints for inversions that estimate slip rates. Here, we present a new inverse approach that utilizes both surface velocities and subsurface stressing‐rate tensors to constrain interseismic slip rates and activity of closely spaced faults. We assess the ability of the inverse approach to recover slip rate distributions from stressing‐rate tensors and surface velocities generated by two forward models: (a) a single strike‐slip fault model and (b) a complex southern San Andreas fault system (SAFS) model. The single fault model inversions reveal that a sparse array of regularly spaced stressing‐rate tensors can recover the forward model slip distribution better than surface velocity inversions alone. Because focal mechanism inversions currently provide normalized deviatoric stress tensors, we perform inversions for slip rate using full, deviatoric or normalized deviatoric forward‐model‐generated stressing‐rate tensors to assess the impact of removing stress magnitude from the constraining data. All the inversions, except for those that use normalized deviatoric stressing‐rate tensors, recover the forward model slip‐rate distribution well, even for the SAFS model. Jointly inverting stressing rate and velocity data best recovers the forward model slip‐rate distribution and may improve estimates of interseismic deep slip rates in regions of complex faulting, such as the southern SAFS; however, successful inversions of crustal data will require methods to estimate stressing‐rate magnitudes.
Integrated compact regulators of protein activity enable control of signaling pathways and genome-editing in vivo
Authors: Franko Nik , da Silva Santinha António José , Xue Shuai , Zhao Haijie , Charpin-El Hamri Ghislaine , Platt Randall Jeffrey , Teixeira Ana Palma , Fussenegger Martin 
Published: January 2024

AbstractViral proteases and clinically safe inhibitors were employed to build integrated compact regulators of protein activity (iCROP) for post-translational regulation of functional proteins by tunable proteolytic activity. In the absence of inhibitor, the co-localized/fused protease cleaves a target peptide sequence introduced in an exposed loop of the protein of interest, irreversibly fragmenting the protein structure and destroying its functionality. We selected three proteases and demonstrated the versatility of the iCROP framework by validating it to regulate the functional activity of ten different proteins. iCROP switches can be delivered either as mRNA or DNA, and provide rapid actuation kinetics with large induction ratios, while remaining strongly suppressed in the off state without inhibitor. iCROPs for effectors of the NF-κB and NFAT signaling pathways were assembled and confirmed to enable precise activation/inhibition of downstream events in response to protease inhibitors. In lipopolysaccharide-treated mice, iCROP-sr-IκBα suppressed cytokine release (“cytokine storm”) by rescuing the activity of IκBα, which suppresses NF-κB signaling. We also constructed compact inducible CRISPR-(d)Cas9 variants and showed that iCROP-Cas9-mediated knockout of the PCSK9 gene in the liver lowered blood LDL-cholesterol levels in mice. iCROP-based protein switches will facilitate protein-level regulation in basic research and translational applications.
Greenhouse gas emissions from US irrigation pumping and implications for climate-smart irrigation policy
Authors: Driscoll Avery W. , Conant Richard T. , Marston Landon T. , Choi Eunkyoung , Mueller Nathaniel D. 
Published: January 2024

AbstractIrrigation reduces crop vulnerability to drought and heat stress and thus is a promising climate change adaptation strategy. However, irrigation also produces greenhouse gas emissions through pump energy use. To assess potential conflicts between adaptive irrigation expansion and agricultural emissions mitigation efforts, we calculated county-level emissions from irrigation energy use in the US using fuel expenditures, prices, and emissions factors. Irrigation pump energy use produced 12.6 million metric tonnes CO2e in the US in 2018 (90% CI: 10.4, 15.0), predominantly attributable to groundwater pumping. Groundwater reliance, irrigated area extent, water demand, fuel choice, and electrical grid emissions intensity drove spatial heterogeneity in emissions. Due to heavy reliance on electrical pumps, projected reductions in electrical grid emissions intensity are estimated to reduce pumping emissions by 46% by 2050, with further reductions possible through pump electrification. Quantification of irrigation-related emissions will enable targeted emissions reduction efforts and climate-smart irrigation expansion.
Emergence of multidrug resistant, ctx negative seventh pandemic Vibrio cholerae O1 El Tor sequence type (ST) 69 in coastal water of Kerala, India
Authors: Ayyappan Minimol V. , Kishore Pankaj , Panda Satyen Kumar , Kumar Anuj , Uchoi Devananda , Nadella Ranjit Kumar , Priyadarshi Himanshu , Obaiah Mohan Chitradurga , George Dybin , Hamza Muneeb , Ramannathan Sreelekshmi K. , Ravishankar C. N. 
Published: January 2024

AbstractSeventh pandemic Vibrio choleare O1 El Tor strain is responsible for the on-going pandemic outbreak of cholera globally. This strain evolved from non-pathogenic V. cholerae by acquiring seventh pandemic gene (VC 2346), pandemic Islands (VSP1 and VSP2), pathogenicity islands (VP1 and VP2) and CTX prophage region. The cholera toxin production is mainly attributed to the presence of ctx gene in these strains. However, several variants of this strain emerged as hybrid strains or atypical strains. The present study aimed to assess the aquatic environment of Cochin, India, over a period of 5 years for the emergence of multidrug resistant V. cholerae and its similarity with seventh pandemic strain. The continuous surveillance and monitoring resulted in the isolation of ctx negative, O1 positive V. cholerae isolate (VC6) from coastal water, Cochin, Kerala. The isolate possessed the biotype specific O1 El Tor tcpA gene and lacked other biotype specific ctx, zot, ace and rst genes. Whole genome analysis revealed the isolate belongs to pandemic sequence type (ST) 69 with the possession of pandemic VC2346 gene, pathogenic island VPI1, VPI2, and pandemic island VSP1 and VSP2. The isolate possessed several insertion sequences and the SXT/R391 family related Integrative Conjugative Elements (ICEs). In addition to this, the isolate genome carried virulence genes such as VgrG, mshA, ompT, toxR, ompU, rtxA, als, VasX, makA, and hlyA and antimicrobial resistance genes such as gyrA, dfrA1, strB, parE, sul2, parC, strA, VC1786ICE9-floR, and catB9. Moreover, the phylogenetic analysis suggests that the isolate genome is more closely related to seventh pandemic V.cholerae O1 N16961 strain. This study reports the first incidence of environmental ctx negative seventh pandemic V. choleare O1 El Tor isolate, globally and its presence in the aquatic system likely to induce toxicity in terms of public health point of view. The presence of this isolate in the aquatic environment warns the strict implementation of the epidemiological surveillance on the occurrence of emerging strains and the execution of flagship program for the judicious use of antibiotics in the aquatic ecosystem.
Arterial stiffness assessment using PPG feature extraction and significance testing in an in vitro cardiovascular system
Authors: Ferizoli Redjan , Karimpour Parmis , May James M. , Kyriacou Panicos A. 
Published: January 2024

AbstractCardiovascular diseases (CVDs) remain the leading cause of global mortality, therefore understanding arterial stiffness is essential to developing innovative technologies to detect, monitor and treat them. The ubiquitous spread of photoplethysmography (PPG), a completely non-invasive blood-volume sensing technology suitable for all ages, highlights immense potential for arterial stiffness assessment in the wider healthcare setting outside specialist clinics, for example during routine visits to a General Practitioner or even at home with the use of mobile and wearable health devices. This study employs a custom-manufactured in vitro cardiovascular system with vessels of varying stiffness to test the hypothesis that PPG signals may be used to detect and assess the level of arterial stiffness under controlled conditions. Analysis of various morphological features demonstrated significant (p < 0.05) correlations with vessel stiffness. Particularly, area related features were closely linked to stiffness in red PPG signals, while for infrared PPG signals the most correlated features were related to pulse-width. This study demonstrates the utility of custom vessels and in vitro investigations to work towards non-invasive cardiovascular assessment using PPG, a valuable tool with applications in clinical healthcare, wearable health devices and beyond.
Immersive experiences in museums for elderly with cognitive disorders: a user-centered design approach
Authors: Yi Xinyue , Liu Zhizheng , Li Hong , Jiang Bo 
Published: January 2024

AbstractIn the context of global aging, to explore the design needs of elderly with dementia in museum environments, to establish a user cognitive psychological model based on immersion theory, and to enhance the satisfaction of cognitively impaired dementia with the museum service experience. Using literature research, surveys, questionnaires, interviews, and focus groups, we analyze the experience design from the psychological demands of elderly with dementia, build a method of mining user needs by combining the KANO model with the analytic hierarchy process (AHP) method, and establish a model for evaluating the excellence of the experience of the museum environment. The conclusion shows that displaying museum virtual scenes or old objects can effectively increase the subjective well-being of people suffering from various health conditions. The method can accurately tap the attributes of the needs of elderly with dementia, break through the drawbacks of the traditional museum experience design which is dominated by the designer's subjective consciousness, and allow the audience to better experience the museum immersive experience, which provides a new idea and method for the effectiveness of cognitive interventions for elderly with cognitive disorders.
High-performance hydrogen gas sensor system based on transparent coaxial cylinder capacitive electrodes and a volumetric analysis technique
Authors: Jung Jae K. , Lee Ji H. 
Published: January 2024

AbstractA high-performance H2 gas sensor system based on capacitive electrodes and a volumetric analysis technique were developed. Coaxial capacitive electrodes were fabricated by placing a thin copper rod in the center and by adhering a transparent conductive film on the exterior surface of a graduated cylinder. Thus, H2 from a polymer specimen lowered the water level in the cylinder between the two electrodes, producing measurable changes in capacitance that allowed for the measurement of the H2 concentration emitted from the specimen enriched by H2 under high-pressure conditions. The sensing system detected diffused/permeated hydrogen gas from a specimen and hydrogen gas leaks caused by imperfect sealing. The hydrogen gas sensor responded almost instantly at 1 s and measured hydrogen concentrations ranging from 0.15 to 1500 ppm with controllable sensitivity and a measurable range. In addition, performance tests with polymer specimens used in hydrogen infrastructure verified that the sensor system was reliable; additionally, it had a broad measurement range to four decimal places. The sensor system developed in this study could be applied to detect and characterize pure gases (He, N2, O2 and Ar) by real time measurement.