bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inner strength amidst pandemic: Teachers' self‐efficacy patterns and perceived personal accomplishments
Authors: Ha Cheyeon , Pressley Tim 
Published: January 2024

AbstractThe present study explored the teachers' self‐efficacy patterns and perceived personal accomplishment in the coronavirus disease 2019 pandemic teaching environment. The current sample included in‐service teachers (n = 393) representing 36 states across the United States. We explored whether teacher efficacy variables (i.e., engagement efficacy, instruction efficacy, and classroom management) predict their perceived personal accomplishment. Also, based on the clustering analysis, we explored how teachers' different self‐efficacy patterns related to their perceived personal accomplishment. The results indicate that teacher efficacy strongly predicted their personal accomplishment levels and show insightful implications on how to support teachers to recover well‐being in a post‐pandemic learning environment.
Insights into the function of the chloroplastic ribosome‐associated GTPase high frequency of lysogenization X in Arabidopsis thaliana
Authors: Mehrez Marwa , Lecampion Cécile , Ke Hang , Gorsane Faten , Field Ben 
Published: January 2024

AbstractRibosome‐associated GTPases are conserved enzymes that participate in ribosome biogenesis and ribosome function. In bacteria, recent studies have identified HflX as a ribosome‐associated GTPase that is involved in both ribosome biogenesis and recycling under stress conditions. Plants possess a chloroplastic HflX homolog, but its function remains unknown. Here, we characterized the role of HflX in the plant Arabidopsis thaliana. Our findings show that HflX does not affect normal plant growth, nor does it play an essential role in acclimation to several different stresses, including heat, manganese, cold, and salt stress under the conditions tested. However, we found that HflX is required for plant resistance to chloroplast translational stress mediated by the antibiotic lincomycin. Our results suggest that HflX is a chloroplast ribosome‐associated protein that may play a role in the surveillance of translation. These findings provide new insight into the function of HflX as a ribosome‐associated GTPase in plants and highlight the importance of investigating conserved proteins in different organisms to gain a comprehensive understanding of their biological roles.
HB‐EGF‐loaded nanovesicles enhance trophectodermal spheroid attachment and invasion
Authors: Poh Qi Hui , Rai Alin , Cross Jonathon , Greening David W. 
Published: January 2024

AbstractThe ability of trophectodermal cells (outer layer of the embryo) to attach to the endometrial cells and subsequently invade the underlying matrix are critical stages of embryo implantation during successful pregnancy establishment. Extracellular vesicles (EVs) have been implicated in embryo‐maternal crosstalk, capable of reprogramming endometrial cells towards a pro‐implantation signature and phenotype. However, challenges associated with EV yield and direct loading of biomolecules limit their therapeutic potential. We have previously established generation of cell‐derived nanovesicles (NVs) from human trophectodermal cells (hTSCs) and their capacity to reprogram endometrial cells to enhance adhesion and blastocyst outgrowth. Here, we employed a rapid NV loading strategy to encapsulate potent implantation molecules such as HB‐EGF (NVHBEGF). We show these loaded NVs elicit EGFR‐mediated effects in recipient endometrial cells, activating kinase phosphorylation sites that modulate their activity (AKT S124/129, MAPK1 T185/Y187), and downstream signalling pathways and processes (AKT signal transduction, GTPase activity). Importantly, they enhanced target cell attachment and invasion. The phosphoproteomics and proteomics approach highlight NVHBEGF‐mediated short‐term signalling patterns and long‐term reprogramming capabilities on endometrial cells which functionally enhance trophectodermal‐endometrial interactions. This proof‐of‐concept study demonstrates feasibility in enhancing the functional potency of NVs in the context of embryo implantation.
Development of transparent, particle‐loaded photoresins for volumetric additive manufacturing of silica glass
Authors: Myers Luke A. , Schwartz Johanna J. , De Beer Martin P. , Walton Rebecca L. , Porcincula Dominique H. 
Published: January 2024

AbstractAdditive manufacturing of glass aims to change the paradigm of glass manufacturing by allowing for improved customization coupled with lower energy and post‐processing needs. Fabrication of glass via volumetric additive manufacturing (VAM) involves printing in a silica‐loaded photopolymer resin with subsequent thermal processing and adds additional advantages by allowing for rapid printing of parts with smooth surfaces and no supports. Previous work in glass VAM has demonstrated fabrication of optical quality microoptics with overall dimensions on the scale of tens of cubic millimeters. For applications requiring glass printed on the scale of cubic centimeters the rheology, scattering, and green part strength must be controlled via resin formulation. Here, we present insight into a novel glass photopolymer resin suitable for VAM and in the effect of tuning formulation on the ability to produce dense glass parts with volumes on the scale of cubic centimeters.
Hetero‐blast from a structural reactive material cylinder under explosive loading
Authors: Zhang Fan , Yoshinaka Akio , Ripley Robert C. 
Published: January 2024

AbstractA structural reactive material (SRM) cylinder is considered here as a limiting case of a dense metallic energetic system in which a mixture of metal particles is consolidated to the theoretical maximum density excluding porosity, to possess both high energy density and mechanical strength. Dynamic fragmentation and free‐field explosion of a 103 mm inner diameter SRM cylinder charge is experimentally studied, with a wall thickness varying in a range of metal‐to‐explosive mass ratioM/C=1.3 to 4.0. Under explosive loading, the SRM cylinder produces a designated fragment size distribution divided into two groups: fine fragments with sizes on the order of 102 μm and below, and coarse fragments with sizes on the order ranging between 100‐101 mm. Prompt detonation shock‐induced reaction (DSIR) of the expanding cloud of high‐concentration fine fragments supplements the energy to enhance the primary blast as it propagates, while the coarse fragments form a high‐speed, high‐concentration metal momentum flux crossing the fireball and blast front to contribute to the total impulse loading to a nearby structure. Rapid impact‐induced reaction (IIR) of the secondary fragments from high‐speed coarse SRM fragments further enhances the reflected blast loading or generates a high interior explosion pressure as fragments perforate into the structure. The above distinctive characteristics of a unique hetero‐blast are coupled effectively in the near‐field range.
Impact of body position on hemodynamic measurements during exercise: A tale of two bikes
Authors: Kirupaharan Pradhab , Lane James , Melillo Celia , Paul Deborah , Amoushref Alla , Abdi Sami Al , Tonelli Adriano R. 
Published: January 2024

AbstractThe addition of exercise testing during right heart catheterization (RHC) is often required to accurately diagnose causes of exercise intolerance like early pulmonary vascular disease, occult left heart disease, and preload insufficiency. We tested the influence of body position (supine vs. seated) on hemodynamic classification both at rest and during exercise. We enrolled patients with exercise intolerance due to dyspnea who were referred for exercise RHC at the Cleveland Clinic. Patients were randomized (1:1) to exercise in seated or supine position to a goal of 60 W followed by maximal exercise in the alternate position. We analyzed 17 patients aged 60.3 ± 10.9 years, including 13 females. At rest in the sitting position, patients had significantly lower right atrial pressure (RAP), mean pulmonary artery pressure (mPAP), pulmonary artery wedge pressure (PAWP) and cardiac index (CI). In every stage of exercise (20, 40, and 60 W), the RAP, mPAP, and PAWP were lower in the sitting position. Exercise in the sitting position allowed the identification of preload insufficiency in nine patients. Exercise in either position increased the identification of postcapillary pulmonary hypertension (PH). Body position significantly influences hemodynamics at rest and with exercise; however, mPAP/CO and PAWP/CO were not positionally affected. Hemodynamic measurements in the seated position allowed the detection of preload insufficiency, a condition that was predominantly identified as no PH during supine exercise.
Green synthesis of Dextrin‐graft‐poly(allyl amine‐co‐methacrylic acid)/reduced graphene oxide composite and its application for dye and pesticide removal from the aqueous medium
Authors: Ray Jagabandhu , Sasmal Dinabandhu , Jana Subinoy , Tripathy Tridib 
Published: January 2024

AbstractA Dextrin‐graft‐poly(allyl amine‐co‐methacrylic acid)/reduced graphene oxide (DEXTGP/RGO) is synthesized through the grafting of a combination of allyl amine (AAM) and methacrylic acid (MAA) monomers onto the dextrin polysaccharide backbone by using the free radical copolymerization technique in an aqueous medium, with potassium peroxydisulfate serving as the initiator followed by the partial reduction of graphene oxide (GO). Various characterization techniques including FTIR, 1H/13C NMR, XRD, FESEM, EDAX, and BET analysis are utilized to characterize both the synthesized DEXTGP/RGO composite and graft copolymer. Investigations are conducted on multiple operational variables, including adsorption kinetics, isotherms, and thermodynamic parameters, for the adsorption of both MB and PL. Both intra‐particle diffusion kinetic model and pseudo‐second‐order kinetics are observed to follow for the adsorption of MB, while the Langmuir isotherm model provided a good fit for the equilibrium data. In contrast, the adsorption of PL displayed solely pseudo‐second‐order kinetics, while the equilibrium data shows good agreement with both the Langmuir and Dubinin‐Radushkevich isotherm models. Maximum adsorption capacity (
) of the RGO composite is found to be 932.56 mg/g for MB and 311.63 mg/g for PL. The thermodynamic analysis revealed that the adsorption of dye and pesticide onto the RGO composite is a spontaneous process.
Recent Advances on the Development of Early Transition Metal Complexes for Photo‐Assisted Cytotoxicity Applications
Authors: Wahengbam Sharmila , Musib Dulal , Roy Mithun 
Published: January 2024

AbstractFor targeted therapy, the strategic use of an inactive precursor or “prodrug” could be an attractive strategy. Photo‐assisted chemotherapy offers a smart opportunity for developing new inorganic prodrugs for selective and temporal regulation on the chemotherapeutic activity of the prodrugs with light. The 3d transition metal complexes with versatile coordination number and geometry, redox, thermodynamic and kinetic properties, the presence of low‐energy metal‐centered electronic transitions, and the ability to exhibit light‐assisted chemical reactions have emerged as strategic tools for photo‐chemotherapeutic applications. Transition metal complexes are typically characterized by metal‐centered, ligand to metal, metal to ligand or intra‐ligand electronic transitions, and photo‐activated electronic states of the transition metal complexes potentially exhibit a wide range of chemical reactions viz. intramolecular oxido‐reduction reactions, intramolecular rearrangements, ligand exchange reactions or energy transfer those cascades into the generation of ROS (⋅OH, O2−⋅, O22−, 1O2), small molecules like H2, N2, CO or NO, and alkyl or aryl radicals. Applications of photo‐activable transition metal complexes for generating cytotoxic ions or radicals in the presence of light have emerged as an attractive strategy for photo‐activated chemotherapy (PACT). Here in, we reviewed the photophysical and photochemical aspects of the early transition metal complexes exhibiting photo‐ activated chemotherapy.
An Experimental and Computational Approach to The Microwave‐Assisted Synthesis of 2’‐Hydoxychalcone Derivatives in 1‐Dodecyl‐3‐Methylimidazolium Bromide ([DDMIm]Br) Ionic Liquids
Authors: Wahyuningrum Deana , Nur Pasya Nadya , Eduardus Eduardus , Handayani Nurrahmi , Damayanti Sophi 
Published: January 2024

AbstractFour derivatives of 2’‐hydoxychalcone were synthesized through Claisen‐Schmidt condensation by combining 2’‐hydroxyacetophenone and four different benzaldehyde derivatives (o‐vanillin, salicylaldehyde, p‐anisaldehyde, and benzaldehyde) in the presence of a base. The reactions took place in an ionic liquid, 1‐dodecyl‐3‐methylimidazolium bromide ([DDMIm]Br), and were facilitated by microwave irradiation. The reactions were completed within 10 to 15 minutes, yielding products with chemical yields ranging from 52.64 % to 83.42 %. The structures of the synthesized products were confirmed using 1H NMR and 13C NMR spectroscopy. Additionally, antimicrobial activity tests demonstrated the effectiveness of specific derivatives against Staphylococcus aureus and Escherichia coli, underscoring the importance of hydroxy and methoxy groups on the aromatic ring in inhibiting microbial growth. These findings provide valuable knowledge for developing chalcone derivatives with improved properties and potential applications in drug discovery. Furthermore, the synthesized products′ reactivity was analyzed using Frontier Molecular Orbital (FMO) and their reactivity site was mapped using Molecular Electrostatic Potential (MEP). Lastly, molecular docking analysis was attempted to explain antibacterial activities from all products. Nonetheless, the molecular docking simulations conducted in this study were inadequate to fully account for the antimicrobial activity observed in all the products.
Design of New Second‐Generation TRK Inhibitors Targeting Tropomyosin Receptor Kinases by Using Molecular Docking, Molecular Dynamics Simulations and ADMET Properties
Authors: Zhao Kaihui , Cui Yang , Tang Wenhao , Shi Kang , Pan Haiyu , Zhong Qidi 
Published: January 2024

AbstractTRK, as a type of cell surface protein, plays a critical role in various biological processes, particularly as a key target for cancer treatment. We explored the correlation between the structure and activity of indole‐2‐one derivatives through investigations involving 3D‐QSAR molecular modelling, molecular docking, molecular dynamics, and ADMET property research. The statistical data from the CoMFA and CoMSIA models exhibit excellent internal stability (CoMFA: q2=0.622, r2=0.992; CoMSIA: q2=0.740, r2=0.972). Further molecular docking unveiled the interaction mechanism between small molecules and receptor proteins, demonstrating that the hydrogen bonding between amino acids Met590 and Glu592 and small molecules could enhance the ligand‐receptor binding affinity. Based on the 3D‐QSAR model and molecular docking, we designed and predicted the activity of eight new molecules, which displayed high expected activity. Subsequently, through 100 ns MD simulations and binding free energy calculations, we affirmed the stability of the molecular docking results. Finally, we employed ADMET to predict the pharmacokinetic properties of the newly designed molecules, validating their commendable drug‐like characteristics. These research findings provide valuable references for the design and development of novel TRK inhibitors, offering fresh perspectives for subsequent drug design.
Autonomous vehicle security: Current survey and future research challenges
Authors: Pali Isha , Amin Ruhul , Abdussami Mohammad 
Published: January 2024

SummaryThe advancement in technology and the adoption of innovative developments have made our lives easier. Every industry, from agriculture to transport, has experienced this advancement. The entire transportation system is in the process of becoming intelligent. Smart mobility of autonomous vehicles is an important part of the upcoming smart cities. The autonomous vehicle provides functionalities for safety and convenience. It has been an emerging field with a lot of attention and still under advancement and requires a thorough study and solutions for potential challenges and opportunities. Despite impressive advantages, it has some security vulnerabilities which could lead to life‐threatening consequences. Though they could prevent road accidents by eliminating human errors from the driving process, they also create the possibility of cyber‐physical attacks on the vehicular controlling system. For this, many researchers have focused on the security attacks and defenses in autonomous vehicular systems. A 360‐degree research has been undertaken to understand the concept of autonomous vehicles entirely, such as history, social impacts, difficulties and challenges, current product developments, and security aspects. Also, a vehicular architecture is proposed by integrating various technologies such as 5G, SDN, cloud, and so forth, its possible security attacks are mentioned.
Influence of modeling choices and prior information on the Bayesian assessment of a reinforced concrete bridge
Authors: Vereecken Eline , Botte Wouter , Lombaert Geert , Caspeele Robby 
Published: January 2024

AbstractA lot of bridges are aging and reaching the anticipated service life. To gain insight in their remaining resistance, inspections and measurements can be performed. The resulting information and data can be used to update variables in the degradation models of these bridges. To account for spatial variation, degradation variables can be modeled with random fields. The random fields of the degradation variables are updated based on a Bayesian inference procedure, where different types of heterogenous and indirect data are accounted for. Nevertheless, in this procedure, various assumptions need to be made, such as the quantification of measurement uncertainty, the structural and degradation model to be used, the prior distributions of the variables of interest, and so forth. These assumptions can influence the results of the Bayesian inference. Hence, in this work, it will be investigated what the influence is of different assumptions and how they affect the localization and quantification of damage. This will be done by application to a reinforced concrete girder bridge. The main conclusions are that the model used in the Bayesian inference procedure should resemble the actual structure as good as possible and that simplifications that are allowed in the design can lead to posterior distributions deviating a lot from the actual situation. Moreover, it is illustrated how information from visual observations can be included in the definition of the prior distributions and how this has a beneficial effect on the posterior predictions.
Diversifying “English” at the Decolonial Turn
Authors: Canagarajah Suresh 
Published: January 2024

AbstractIn this brief forum article, I draw from the disciplinary orientation of linguistic anthropology to discuss how a collection of linguistic and semiotic resources gets enregistered as the “language” for specific communicative activities. Enregisterment is an ongoing social and ideological process whereby a semiotic corpus gets identified as conventional for an activity or identity (see Agha, 2005). At a larger scale of consideration, it can also help explain what is identified as “English” in any given time and place. It is more appropriate to focus on communicative activity as the unit of analysis for the diverse semiotic resources constituting it, rather than assuming a labeled language as the starting point for our teaching or research. In place of relying on formal proficiency in English grammar, which might have variable relevance in communicative practices, we must prepare students for the diverse semiotic repertoires needed for their purposes and develop in them the dispositions to always attune to the mix of entangled resources in any activity.
Post‐combustion capture and other Carbon Capture and Sequestration (CCS) technologies: A review
Authors: Ibigbami Olayinka Abidemi , Onilearo Oluwatimilehin Daniel , Akinyeye Richard Odunayo 
Published: January 2024

AbstractTechnologies for capturing and storing carbon dioxide (CO2) and strategies for sequestering carbon dioxide have received a lot of interest in recent years as potential remedies for the curtailment of the growing concerns of emissions of greenhouse gases and global warming. This article provides a comprehensive analysis on the trends in research and development in the area of CO2 carbon capture and sequestration at the moment. The review explores various technological approaches for capturing CO2 from industrial emissions, such as post‐combustion capture systems, pre‐combustion capture systems, and oxy‐fuel combustion system. It also gives a major insight into the post‐combustion capture of carbon by means of a summary, information obtained via a personal interview with a Combustion Based Unit (CBU) plant manager. Additionally, different methods for storing and sequestering the aforementioned gas, including geological and oceanic archiving, and mineralization, are examined. By synthesizing the findings from a wide range of studies and research papers, this literature review provides valuable insights into the current technologies for CO2 capture, storage, and sequestration, contributing to the ongoing efforts in addressing climate change and achieving sustainable development goals.
Maternal supplementation with docosahexaenoic acid does not cause constriction of fetal ductus arteriosus: randomized controlled trial
Authors: Zielinsky P. , Alves D. R. , Foresti J. D. Á. , Guimarães D. B. , Zucatti K. P. , Vian I. 
Published: January 2024

ABSTRACTObjectiveDocosahexaenoic acid (DHA) is recommended routinely in pregnancy to promote fetal development. DHA has anti‐inflammatory activity, but its effects on the fetal heart and circulation are unknown. This study aimed to investigate whether maternal DHA supplementation in the third trimester affects maternal prostaglandin levels and fetal ductus arteriosus flow dynamics.MethodsThis was a double‐blind randomized controlled trial with parallel groups conducted between 2018 and 2021. Pregnant women aged over 18 years with a normal fetus at 27–28 weeks' gestation showing no cardiac/extracardiac anomalies or ductal constriction were eligible for the trial. Women consuming substances with a known inhibitory effect on prostaglandin metabolism, such as non‐steroidal anti‐inflammatory drugs and polyphenol‐rich foods, were excluded. The intervention group received oral supplementation of omega‐3 with 450 mg/day of DHA for 8 weeks and the placebo group received capsules of soy lecithin for 8 weeks. Anthropometric measurements, assessment of polyphenol and omega‐3 consumption, fetal morphological ultrasound examination, fetal Doppler echocardiographic examination and blood sample collection were performed at the start of the study and the latter two were repeated at follow‐up. Prostaglandin E2 (PGE2) level and echocardiographic parameters were compared between the intervention and placebo groups and between baseline and follow‐up.ResultsA total of 24 participants were included in each group. After 8 weeks, there were no significant differences between the intervention and placebo groups in maternal serum PGE2 level or Doppler echocardiographic parameters of ductal flow. No case of ductus arteriosus constriction was observed. The expected intragroup changes in cardiac morphology, as a result of advancing gestation, were present.ConclusionsMaternal DHA supplementation in the third trimester at a clinically recommended dose did not result in inhibition of PGE2 or constriction of the ductus arteriosus. These findings should be confirmed in postmarket surveillance studies with larger patient numbers in order to test the full safety profile of DHA and provide robust clinical reassurance. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.