bluuebunny/crossref_metadata_2025_split huggingface dataset:
RUIN PROBABILITY IN THE CLASSICAL RISK PROCESS WITH WEIBULL CLAIMS DISTRIBUTION
Authors: Hamzah Dadang Amir , Siahaan Theresia Stefany Anawa , Pranata Vania Chrestella 
Published: December 2023

In the classical risk process, ruin is the situation when the surplus falls below zero. Ruin probability is a tool used to predict bankruptcy in the insurance company. The ruin probability can be determined by solving the Integral-Differential equation that arises from the classical risk process. In this paper, we are interested in calculating the ruin probability when the claim distribution follows the Weibull distribution. Based on the Weibull parameter, the calculation is divided into two cases: when alpha equals 1 and when . The Laplace transform gives the analytical solution of the Integral-Differential equation. However, when the analytical solution cannot be determined since the Laplace transform is no longer applicable due to the presence of an improper integral that is not possible to solve analytically. Therefore, for the case alpha greater than 1, Euler’s method is applied to determine its numerical solution. The accuracy of the numerical solution is validated by comparing it with the analytical solution for the case Then, using the accuracy determined from the first case, we apply the Euler method to determine the numerical solution for the case . The numerical method gives good accuracy to the analytical solution with the order of calculated from until
Studi Analisis Kebutuhan Pengembangan Kurikulum Kecakapan Hidup sebagai Penguatan Profil Pelajar Pancasila di SD
Authors: Novita Freshka Uktolseja  , Nisa Ana Fitrotun , Sutrisna Wibawa  
Published: December 2023

Salah satu tujuan pendidikan adalah dalam rangka membentuk karakter peserta didik yang unggul sesuai dengan falsafah hidup bangsa. Pancasila merupakan falsafah hidup bangsa Indonesia yang harus diinternalisasikan dalam pembelajaran di sekolah dasar. Penelitian ini bertujuan untuk menganalisis kebutuhan terhadap pengembangan kurikulum kecakapan hidup sebagai penguatan profil pelajar pancasila di sekolah dasar. Metode penelitian yang digunakan pada penelitian ini adalah penelitian pengembangan (research and development) dengan menggunakan model ADDIE (analysis, design, develop, implement dan evaluate) yang dibatasi pada tahapan analysis dan design. Teknik pengumpulan data dilakukan dengan teknik observasi, wawancara dan angket/kuesioner. Teknik analisis data dilakukan dengan teknik kualitatif dan kuantitatif. Hasil penelitian yang dilakukan menunjukkan bahwa diperlukan pengembangan kurikulum berbasis kecakapan hidup untuk peningkatan profil pelajar pancasila di SD yang didesain dengan mengintegrasikan aspek head, heart, hand, and health dengan mengintegrasikan 12 kecakapan hidup yaitu peduli/berbagi, relasi interpersonal, komunikasi, kolaborasi, critical thinking & problem solving, manajemen waktu, manajemen uang, leadership, keterampilan domestik, kreatif, kesehatan, keamanan dan keselamatan diri, serta pengelolaan emosi.
Hisse Senedi Piyasası Analizinde Farklı Derin Sinir Ağı Modellerinin Karşılaştırılması
Authors: ÇOBAN Çağrı , HAYAT Elvan 
Published: December 2023

Yatırımcılar, tasarruflarını getiri potansiyeli yüksek varlıklara yönlendirerek portföylerini güçlendirmeyi ve daha yüksek getiri elde etmeyi hedefliyor. Çeşitli finansal araçlar arasında hisse senetleri yüksek getiri potansiyeli sunan yatırım araçları olarak değerlendirilmektedir. Sonuç olarak hisse senedi fiyat tahmini birçok yatırımcı ve araştırmacının merak konusu olmuştur ve olmaya da devam etmektedir. Ancak yüksek getiri arayışı aynı zamanda yüksek riskleri ve belirsizlikleri de beraberinde getiriyor. Bu belirsizliğin temel kaynakları arasında hisse senedi fiyatlarını etkileyen siyasi olaylar, toplumsal gelişmeler, uluslararası ilişkiler ve sektörel değişimler yer alıyor. Bu çok yönlü ve karmaşık faktörlerin tahmini zordur ve hisse senedi fiyat hareketlerini tahmin etme görevini doğası gereği zorlaştırır.
Geleneksel olarak hisse senedi fiyat tahminleri istatistiksel ve ekonometrik yöntemlere dayanmaktaydı. Son yıllarda teknoloji ve bilgisayar bilimlerindeki ilerlemeler, hisse senedi fiyat tahminlerinde yapay zeka ve makine öğrenmesi metodolojilerinin giderek daha fazla kullanılmasına yol açmıştır. 2000'li yıllardan itibaren derin öğrenme yöntemlerinin gelişmesiyle birlikte hisse senedi fiyat hareketlerindeki karmaşık ilişkiler tespit edilmeye başlanmış ve başarılı sonuçlar elde edilmiştir.
Bu çalışmada, çok değişkenli Derin Sinir Ağları (Deep Neural Network-DNN), Evrişimsel Sinir Ağları (Convolutional Neural Network-CNN) ve Tekrarlayan Sinir Ağları (Recurrent Neural Networks-RNN) modelleri kullanılarak hisse senedi fiyatlarını tahmin etmek ve modellerin performanslarını karşılaştırmak amaçlanmıştır. Bu amaçla, Vestel Elektronik Sanayi ve Ticaret A.Ş. (VESTL) için 03/06/2013-28/05/2021 tarihleri arasında günlük hisse senedi kapanış fiyatları serisi ve bu seriye etki edebilecek bağımsız değişkenler ele alınarak analizler yapılmıştır. Analiz sonuçlarına göre, en iyi performans gösteren modelin CNN olduğu belirlenmiş ve bu modelin RMSE değeri 0.0858 olarak hesaplanmıştır.
State Defense Attitudes and Religious Values In The Use of Masks to Prevent Covid-19 at Senior High Scool PK Muhammadiyah Kartasura
Authors: Prasetya Nafilla Titan , Suswardany Dwi Linna 
Published: December 2023

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em>This research aims to </em><em>determine the influence of </em><em>knowledge in creating a sense of participation in national defense among students to prevent the increase in Covid-19 cases in Indonesia. The method used was </em><em>pre-experimental with a one-group pre-test and post-test design approach. </em><em>This research was carried out among all 10th </em><em>grade students at SMA PK Muhammadiyah Kartasura </em><em>on 22 October 2022 with a population of 215 people. This research </em><em>used non-probability sampling with a purposive sampling technique with a total of 30 respondents who met the inclusion and exclusion criteria. Analysis was carried out using the normality statistical test, the paired sample t test, and the Wilcoxon test. This research uses data analysis based on the use of software in the form of the SPSS application. </em><em>The research results show that the </em><em>sig.</em><em> </em><em>0,000</em><em> </em><em> </em><em>The results of the </em><em>paired sample t test </em><em>on education show that </em><em>there is an influence </em><em>between the respondent's knowledge before being given education and Pancasila values, as well as religious values and </em><em>after being given </em><em>education</em><em>. The results of statistical processing carried out using the Wilcoxon attitude test show a sig value. 0.000 indicates that there is </em><em>a significant influence on </em><em>respondents' attitudes before being given education and Pancasila values, as well as religious values and after being given education</em><em>. In conclusion, </em><em>there is </em><em>a significant influence between education, </em><em>respondents' attitudes before being given education and Pancasila values, as well as religious values and after being given education</em><em>.</em><em></em></p><p> </p></td></tr></tbody></table></div><strong><em>Keyword: Covid-19, Defending The Country, Religious Values</em></strong>
Comparación de modelos no lineales para describir curvas de crecimiento del portainjerto limón rugoso (Citrus jambhiri Lush.) bajo condiciones de vivero
Authors: Forlin Alejandro S. , Chabbal Marco D. , Yfran Elvira María de las M. , Giménez Laura I. , Carcaño A. F. , Beltrán V. M. 
Published: December 2023

El objetivo fue encontrar el modelo estadístico que mejor describa el patrón de crecimiento del portainjerto Limón 'Rugoso' (Citrus jambhiri Lusch.) en vivero hasta diámetro de injertación. Para ello se sembró en almácigos y a los 45 días de la emergencia los plantines se trasplantaron a macetas de 5 L con sustrato constituido por cascarilla de arroz (40 %), suelo (40 %), y sustrato comercial (20 %). Se evaluaron variables de crecimiento cada 30 días. Para el crecimiento aéreo se cuantificó: diámetro de cuello (DC); cantidad de hojas (CH), largo del tallo (LT); masa fresca del tallo (MFTa), masa fresca de hojas (MFH), masa seca del tallo (MSTa); masa seca de hojas (MSH). También el crecimiento de raíz mediante: largo de raíz (LR), masa fresca (MFR) y seca de raíz (MSR), y variables totales: masa fresca total (MFTotal); masa seca total (MSTotal) y largo total (LT). Para modelar las curvas de crecimiento se probaron los modelos Logístico, Gompertz y Monomolecular. El modelo Gompertz fue el que mejor ajustó al crecimiento del portainjerto en el tiempo para las variables de crecimiento aéreo (a excepción del número de hojas) y para las variables totales (a excepción del largo total), mientras que el modelo Logístico fue el que mejor ajustó al crecimiento del portainjerto en función del tiempo para las variables de crecimiento radicular. También, obtuvo buen ajuste para las variables número de hojas y largo total, debido a que presentó menor cuadrado medio residual del error comparado con los modelos Logístico, Richards y Monomolecular.
Analysis of the structure of comorbidity in children with gastrointestinal tract pathologies
Authors: Shlieienkova H. O. , Shevchenko N. S. , Tsiura O. M. , Кrutenko N. V. , Voloshyn K. V. , Кovalivska S. O. 
Published: December 2023

Diseases of the gastrointestinal tract take the second place in the structure of somatic pathology in children and adolescents. The number of cases of comorbid pathology also tends to increase. The combination of the most common diseases can be both random and causal relationship, the determination of which is important for improving the health care of the child population.
Objective — to analyse of comorbidities in children with gastrointestinal diseases based on the results of the city specialized children’s gastroenterological department work.
Materials and methods. The performance indicators of Kharkiv City Children’s Clinical Hospital No19 for the period from 01.01.2019 to 31.12.2019 were studied. During 2019, 2633 children aged 5 to 18 years (average age: 10.6±2.9 years) with diseases of the digestive system were hospitalized.
Results. The presence of comorbidity was established in 73.6% of children. The most common among children with diseases of the gastrointestinal tract were manifestations of diseases of the nervous system — 31.8%. Diseases of the endocrine system — 15.4% and cardiovascular system — 15.7% were equally represented. A fairly common pathological condition in patients with gastrointestinal diseases was anemia, which was established in 8.1%. Visual impairment was found in 2.7% children, which coincides with the prevalence of this pathology among the general children’s population.
Conclusions. The leading place is held by the gastroduodenal pathology, notably chronic gastroduodenitis. The presence of comorbidity from other organs and systems was established in 73.6% of children with gastrointestinal diseases. The most common comorbidity in diseases of the gastroduodenal zone are diseases of the nervous system. The greatest chances of combining pathological conditions with the development of comorbid pathology are diseases of the gastroduodenal zone and nervous system, intestines and autoimmune thyroiditis, gastroesophageal reflux diseases and obesity. The results suggest the necessity of additional examination of children with gastrointestinal pathology in order to early diagnosis of comorbidity and provide the required comprehensive assistance.
Modern strategy for management of pediatric patients with gastroesophageal reflux disease in compliance with the international and national guidelines
Authors: Kryuchko T. O. , Nesina I. M. , Poda O. A. , Bubyr L. M. 
Published: December 2023

Recent epidemiological studies demonstrated that gastroesophageal reflux disease (GERD) takes a leading place among acid‑dependent gastroenterological diseases. The problems of GERD development prevention and its treatment are topical since GERD significantly reduces the quality of life, especially when extraesophageal symptoms appear. Timely and correct GERD diagnosis, treatment and monitoring in pediatric patients prevents the development of complicated course of the disease in adults. Last decade, priority attention has been given to improving the quality of medical care in most countries worldwide. To achieve this purpose, effective medical care should be provided and the results of treatment of patients should be improved.
The review presents analysis of current strategies for GERD diagnosis and treatment in pediatric patients based on the international and national guidelines. To ensure the proper quality of medical care, it is necessary to standardize approaches to diagnosis and treatment of diseases in childhood. The preparation of the Medical Standards of Care «Gastroesophageal Reflux Disease in Children» by a multidisciplinary group of experts and the adaptation of the clinical guideline are purposed to the improvement of existing diagnostic and treatment approaches to GERD pediatric patients in Ukraine, to ensuring high‑quality and effective medical care and establishing the uniform requirements for prevention, diagnosis and treatment of this group of patients. The results of modern investigations, based on international consensuses on the GERD diagnosis and treatment in childhood, have been highlighted. The latest information on the expediency of administration of instrumental examinations and treatment tactics has been presented.
Cortisol level in mixed saliva as a marker of periodontal lesions in metabolic associated diseases
Authors: Emelyanova N. Y. 
Published: December 2023

Dysregulation of cortisol levels at account of the increase in inflammatory mediators increases the risk of developing metabolic associated diseases, suppresses secretion of secretory immunoglobulins and neutrophil function, which results in a decrease in protection against periodontal pathogens in the oral cavity.
Objective — to evaluate the possible association of salivary cortisol levels with the main inflammatory markers of metabolic associated diseases and periodontal disease.
Materials and methods. The study included 67 patients, 44 of whom had cardiometabolic diseases. The comparison group consisted of patients, matched by sex and age who did not have clinical manifestations of metabolic associated diseases. To confirm the underlying disease, patients underwent assessment of carbohydrate and lipid metabolism, questionnaire survey on the main dental complaints and a dental examination, and evaluation of salivation rate, saliva viscosity and determination of cortisol level of mixed saliva with enzyme linked immunosorbent assay. Statistical analysis was performed using SPSS software with the calculation of the mean value M, standard error, Student’s test. Percentages were compared using the z‑criterion. The Pearson correlation test was used to identify the relationship between indicators.
Results. Significantly higher levels of mixed salivary cortisol were recorded in patients of the main group (3.34±0.20 ng/ml) (p <0.05). Direct correlation has been established between cortisol levels and presence of diabetes mellitus (r=0.342; p=0.016), levels of blood glucose (r=0.379; p=0.002), low‑density lipoprotein cholesterol (r=0.348; p=0.017); indirect correlation was established with non‑alcoholic fatty liver disease (NAFLD) through triglycerides levels (r=0.345; p=0.007). In addition, reverse correlations were observed between cortisol and alkaline phosphatase (r=–0.328; p=0.0014), salivation rate and the presence of metabolic associated diseases (the most significant with NAFLD (r=–0.499; p=0.000)).
Conclusions. Under conditions of prolonged chronic stress, patients with metabolic associated diseases have a significantly increased rate of gingival lesions. The study of cortisol in mixed saliva is a convenient non‑invasive method that allows the assessment of the presence of chronic stress in patients, as well as its impact on the development, duration, chronicity and response to treatment of metabolic associated diseases.
The significance of catestatin and relaxin-2 in the diagnosis of myocardial remodeling in patients with essential hypertension and type 2 diabetes mellitus
Authors: Pankova O. A. , Korzh O. M. 
Published: December 2023

Objective — to evaluate the peculiarities of electrocardiographic (ECG) and echocardiographic (EchoCG) parameters in patients with essential hypertension (EH) in combination with type 2 diabetes mellitus (T2DM) and their relationships with plasma catestatin (CTS) and relaxin­‑2 (RLN­­2) levels.
Materials and methods. Examinations involved 106 patients with EH, from whom 55 subjects had concomitant T2DM, and 30 practically healthy volunteers. The mean age of the participants was (64.06±8.44) years, and women prevailed in the patients’ group (55.9%). All study participants underwent anthropometric data measurement, laboratory and instrumental investigations. The levels of biomarkers CTS and RLN­­2 were determined with the enzyme‑linked immunosorbent assay. Instrumental investigations included electrocardiography and transthoracic echocardiography.
Results. CTS levels were reduced in patients with concentric (5.04±1.14 ng/mL) and eccentric left ventricular hypertrophy (LVH) (5.08±0.89 ng/mL) compared with the normal geometry (6.63±0.73 ng/mL, p <0.001). The significant correlation has been established between CTS levels and ECG parameters of LVH (Cornell voltage criterion (r=–0.222; p=0.009) and Sokolow‑Lyon index (r=–0.226; p=0.008)), and EchoCG parameters, including LV end‑diastolic dimension (EDD (r=–0.388; p <0.001), LV end‑systolic dimension (ESD (r=–0.453; p <0.001), LV end‑diastolic volume index (EDVi (r=–0.329; p <0.001), LV end‑systolic volume index ESVi (r=–0.415; p <0.001), LV ejection fraction (EF (r=0.469; p <0.001), septal sickness (SS) (r=–0.593; p <0.001), posterior wall thickness (PWS) (r=–0.647; p <0.001), relative wall thickness (RWS) (r=–0.568; p <0.001), and LV myocardial mass index (LVMi) (r=–0.576; p <0.001). Patients with RLN­­2 ≥ 4.69 pg/mL had higher EchoCG parameters, including LV EDD, LV ESD, LV EDVi, LV ESVi, SV, SS, PWS, RWS, LVMi (p <0.05). In addition, a significant positive relationship between CTS and RLN­­2 levels has been revealed (r=0.191; p=0.026), which was also confirmed in the subgroup of patients with RLN­­2 levels above 4.69 pg/mL (r=0.585; p <0.001).
Conclusions. The decrease in CTS levels at LVH and established correlations with the ECG signs of LVH and EchoCG parameters allow us to consider CTS as a predictor of the development of LVH, especially in patients with EH combined with T2DM.
The relationship between polymorphic variants of the endothelial NO-synthase gene and the course of diabetic nephropathy in patients with type 2 diabetes mellitus
Authors: Nesen A. O. , Semenovykh P. S. , Savicheva K. O. , Galchinska V. Y. 
Published: December 2023

Objective — to identify a possible association between the endothelial nitric oxide synthase (eNOS) gene G894T (rs1799983) polymorphism and the markers of renal function and glucose metabolism in patients with type 2 diabetes mellitus (DM2) with diabetic nephropathy (DN).
Materials and methods. Examinations 126 patients with diabetic nephropathy (DN). The control group included 20 healthy individuals. Patients with DM2 were divided into two groups depending on the eNOS rs1799983 gene polymorphism: group I — patients with DN and G/G genotype eNOS G894T gene (n=80); group II — patients with DN and G/T and T/T genotypes eNOS G894T gene (n=46). Genotyping of the of the eNOS rs1799983 gene polymorphism was performed by the Taq‑Man® Fast Universal PCR Master Mix (Applied Biosystems, USA) and TaqMan® SNP Assay (Applied Biosystems, USA).
Results. It has been established that in patients with DN, the distribution of genotypes of the G894T polymorphism of the eNOS gene corresponded to the Hardy‑Weinberg equilibrium in all groups and does not differ significantly from European populations. In diabetic patients with DN the 3 times higher total frequency of G/T and T/T genotypes eNOS G894T gene was established when compared to the control group. These findings prove the undoubted influence of the T allele on the development of DN in this group of patients. DN patients with genotypes G/T and T/T had significantly higher blood glucose and HOMA index (p <0.05) than G homozygotes (genotype G/G). Patients with DN and G/G genotype eNOS G894T gene had better glomerular filtration rate and lower albuminuria compared to patients with G/T and T/T genotypes (p <0.05).
Conclusions. The establishing of association of eNOS gene polymorphism with the disease and further assessment of individual genetic risk is important for the development of a differentiated approach to the prevention and treatment of DN in patients with DM2 depending on the hereditary predisposition of an individual patient. Therefore, currently one of the most progressive approaches is to develop a strategy for early diagnosis, prognosis and preventive therapy of the disease using genetic markers.
Potentiality of natural live food organisms in shrimp culture: A review
Authors: Sharma Khushbu , Gulati Rachna , Singh Sushma , Kumari Ankur , Sharma Pankaj 
Published: December 2023

The aquaculture industry is growing quickly due to increased fish consumption and a decline in wild fish catch. About half of the world's seafood demand for human consumption is now met by farmed seafood. The aquafeed market is expanding along with the aquaculture sector. Some of the elements in shrimp feed are derived from terrestrial plants and low-value forage fishes (fish meal). It is impossible to produce more fish meals since doing so would harm the ocean's environment and sustainability. The reduction in shrimp feed cost can also be done by introducing low-cost, environment-friendly ingredients in shrimp feed formulation. Therefore, new and ecologically friendly shrimp (Litopenaeus vannamei) feed component sources must be created. Live food organisms are a preferable option for this since they provide a variety of essential amino acids and beneficial triglycerides like fat, vitamins, and colors in their cell metabolites. Microalgae biomasses also represent feasible ingredients for shrimp feed sources. Their distinctive variety of bioactive chemicals can enhance color and pellet quality, act as a bulk element in shrimp feed, and boost the viability of farmed species. Live food organisms have a great economic potential since they have the highest biomass productivity of all photosynthetic organisms. In addition to giving farmers and exporters a better choice for feeding their fish, the availability of on-grown live food would also open up the prospect of improving the performance and quality of the fish and shrimp through bioencapsulation. This review study examines the possibility of generating natural food biomass as a component in shrimp feed.