bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cannabis in Wisikk: a tempting venture
Authors: Stack Ryan , Gould Storm , Malsch Bertrand 
Published: December 2023

Research methodology
This case was developed using a mixture of publicly available documents created by the partner community, general information from public sources like the First Nations Finance Authority (FNFA) website and Government of Canada websites, and personal and first-hand experience of the indigenous coauthor, Storm Gould.

Case overview/synopsis
Wisikk is a Mi’kmaq sovereign reserve territory located in Mi’kmaq’ki in the place that settler governments call Nova Scotia. The community has existed in its location since time immemorial and has been recognized by the settler government since the early 19th century. An opportunity for community-run business has arisen for Wisikk based on the legalization of cannabis throughout Canada in 2018. This case’s protagonist is the community’s Vice-President for Business Development, Andrew Googoo, as he considers bringing a proposal for a cannabis retailing venture to the Chief and Council. Cannabis legalization in Canada left sales policies to the provinces and was silent as to the rules governing cannabis sales by indigenous communities on their sovereign territory. Considering both potential negative impacts to the community, as well as the potential financial benefits from a successful reserve-based cannabis dispensary, Andrew must soon present his initial findings to the Chief and Council for their deliberation and decision. Any venture undertaken by the reserve would require a loan from the FNFA, so Andrew must also consider the projections and reports that the FNFA would require to support their lending decision.

Complexity academic level
The case is appropriate for mid-level or capstone undergraduate and graduate business courses, especially those focused on entrepreneurship, business ownership or indigenous ownership. The case was originally developed for the accounting division of an international undergraduate case competition. In addition to accounting concepts like pro forma/budgeted income statements and decision analysis, it is intended to showcase some legal and cultural features of community-led indigenous business ventures. The idea is for students to explore concepts of sovereignty, community involvement and broader stakeholder impact, as well as more technical accounting and financial concepts.
Treatment preferences of adults and adolescents with alopecia areata: A discrete choice experiment
Authors: Tervonen Tommi , Whichello Chiara , Law Ernest , Mauer Jonathan , Mitra Debanjali , Trapali Myrto , Krucien Nicolas , Hauber Brett 
Published: December 2023

AbstractPRODUCTS with janus kinase (JAK) inhibition have been shown to promote hair regrowth in patients with alopecia areata (AA). To guide drug‐approval and treatment decisions, it is important to understand patients' willingness to accept the potential risks of JAK inhibition in exchange for potential benefits. We quantified the treatment preferences of adult (≥18 years) and adolescent patients (12–17 years) with AA in the US and Europe to determine the trade‐offs they are willing to make between benefits and risks. Preferences for oral AA treatment attributes were elicited using a discrete choice experiment consisting of 12 tasks in which patients chose between two hypothetical treatment alternatives and no treatment. Benefits included the probability of 80%–100% scalp hair regrowth (Severity of Alopecia Tool score ≤ 20) and achieving moderate‐to‐normal eyebrow and eyelash hair. Treatment‐related risks included 3‐year probabilities of serious infection, cancer, and blood clots. Preference estimates were used to calculate the maximum level of each risk that patients were willing to accept for increases in treatment benefits. The most important attribute to both adults (n = 201) and adolescents (n = 120) was a 50% probability of achieving hair regrowth on most or all the scalp; however, adolescents placed greater relative importance on this attribute than did adults. Adults were averse to the risks of serious infection, cancer, and blood clots, whereas adolescents were averse to the risk of cancer. For a 20% increase in the probability of 80%–100% scalp hair regrowth, adults were willing to accept a mean (95% confidence interval) 3‐year risk of serious infection, cancer, and blood clots of 7.4% (5.5–9.3), 2.5% (1.9–3.1), and 9.3% (6.4–12.2). Adolescents were willing to accept a 3‐year risk of cancer of 3.3% (2.4–4.2). Patients with AA in the US and Europe are willing to accept substantial risks to obtain an effective treatment.
Successful treatment of classic Kaposi sarcoma with Trichophyton rubrum–infected onychomycosis and tinea pedis utilizing combination of oral itraconazole and thalidomide
Authors: Chen Jincong , Zheng Yaxuan , Zhu Changhua , Lin Lihang , Su Huichun 
Published: December 2023

AbstractKaposi sarcoma (KS) is a vascular proliferative tumor caused by human herpesvirus 8. At present, the treatment of KS is difficult and refractory. Here, we report a 68‐year‐old man who was diagnosed with a classical KS with tinea pedis and onychomycosis, infected by Trichophyton rubrum, and treated with itraconazole and thalidomide after locational excision of several bigger nodules. The lesions were relieved during treatment, and recurred after discontinuation. Retreatment still achieved good effect and the therapy was tapered down after control. After the whole course of treatment, the skin lesions subsided significantly without obvious adverse reactions, which showed that itraconazole combined with thalidomide may be another effective and safe treatment for KS in some cases.
Leveraging Patients’ Creative Ideas for Innovation in Health Care
Authors: LEE YUNA S. H. , GROB RACHEL , NEMBHARD INGRID , SHALLER DALE , SCHLESINGER MARK 
Published: December 2023

Policy Points
Patients’ creative ideas may inform learning and innovation that improve patient‐centered care.
Routinely collected patient experience surveys provide an opportunity to invite patients to share their creative ideas for improvement. We develop and assess a methodological strategy that validates question wording designed to elicit creative ideas from patients.
Health care organizations should consider how to report and use these data in health care delivery and quality improvement, and policymakers should consider promoting the use of narrative feedback to better understand and respond to patients’ experiences.
ContextLearning health systems (LHSs) have been promoted for a decade to achieve high‐quality, patient‐centered health care. Innovation driven by knowledge generated through day‐to‐day health care delivery, including patient insights, is critical to LHSs. However, the pace of translating patient insights into innovation is slow and effectiveness inadequate. This study aims to evaluate a method for systematically eliciting patients’ creative ideas, examine the value of such ideas as a source of insight, and examine patients’ creative ideas regarding how their experiences could be improved within the context of their own health systems.MethodsThe first stage of the study developed a survey and tested strategies for elicitation of patients’ creative ideas with 600 patients from New York State. The second stage deployed the survey with the most generative open‐ended question sequence within a health care system and involved analysis of 1,892 patients’ responses, including 2,948 creative ideas.FindingsActionable, creative feedback was fostered by incorporating a request for transformative feedback into a sequence of narrative elicitation questions. Patients generate more actionable and creative ideas when explicitly invited to share such ideas, especially patients with negative health care experiences, those from minority racial/ethnic backgrounds, and those with chronic illness. The most frequently elicited creative ideas focused on solving challenges, proposing interventions, amplifying exceptional practices, and conveying hopes for the future.ConclusionsA valid and reliable method for eliciting creative ideas from patients can be deployed as part of routine patient experience surveys that include closed‐ended survey items and open‐ended narrative items in which patients share their experiences in their own words. The elicited creative ideas are promising for patient engagement and innovation efforts. This study highlights the benefits of engaging patients for quality improvement, offers a rigorously tested method for cultivating innovation using patient‐generated knowledge, and outlines how creative ideas can enable organizational learning and innovation.
Rooftop gardening complexities in the Global South: Motivations, practices, and politics
Authors: Turner Sarah , Pham Thi‐Thanh‐Hiên , Ngô Hạnh Thúy , Zuberec Celia 
Published: December 2023

AbstractAn increasing number of urban residents in the Global South are turning to rooftop gardening, whether through soil or hydroponics, to cultivate their own vegetables, fruit, and herbs. In Hanoi, Vietnam’s capital, rooftop gardening serves as an important alternative to traditional wet markets and more recently established supermarkets. In this paper, we examine the motivations, practices, and constraints of Hanoi’s rooftop gardeners, along with the level of government support or disapproval for rooftop gardening. Our study is grounded in critical urban geography and urban political ecology and specific debates regarding informal life politics. Our findings reveal that Hanoi’s rooftop gardeners feel confronted by a critical food safety crisis, emphasising their need to access safe, fresh, and affordable produce through rooftop gardening. Simultaneously, they express scepticism about the capacity and willingness of formal political institutions at both the municipal and national levels to address and resolve these concerns. We explore whether Hanoi’s urban rooftop gardeners can be considered to be engaging in a form of everyday life politics and examine the dynamics emerging in this regard. We conclude by offering potential policy recommendations for Global South cities to support urban gardening communities.
Elevated proton motive force is a tetracycline resistance mechanism that leads to the sensitivity to gentamicin in Edwardsiella tarda
Authors: Li Shao‐hua , Xiang Jiao , Zeng Ying‐yue , Peng Xuan‐xian , Li Hui 
Published: December 2023

AbstractTetracycline is a commonly used human and veterinary antibiotic that is mostly discharged into environment and thereby tetracycline‐resistant bacteria are widely isolated. To combat these resistant bacteria, further understanding for tetracycline resistance mechanisms is needed. Here, GC–MS based untargeted metabolomics with biochemistry and molecular biology techniques was used to explore tetracycline resistance mechanisms of Edwardsiella tarda. Tetracycline‐resistant E. tarda (LTB4‐RTET) exhibited a globally repressed metabolism against elevated proton motive force (PMF) as the most characteristic feature. The elevated PMF contributed to the resistance, which was supported by the three results: (i) viability was decreased with increasing PMF inhibitor carbonylcyanide‐3‐chlorophenylhydrazone; (ii) survival is related to PMF regulated by pH; (iii) LTB4‐RTET were sensitive to gentamicin, an antibiotic that is dependent upon PMF to kill bacteria. Meanwhile, gentamicin‐resistant E. tarda with low PMF are sensitive to tetracycline is also demonstrated. These results together indicate that the combination of tetracycline with gentamycin will effectively kill both gentamycin and tetracycline resistant bacteria. Therefore, the present study reveals a PMF‐enhanced tetracycline resistance mechanism in LTB4‐RTET and provides an effective approach to combat resistant bacteria.
The New Development Bank in Africa: Mid‐term evaluation and lessons learned
Authors: Bradlow Daniel D. , Masamba Magalie L. 
Published: December 2023

AbstractThe New Development Bank (NDB) launched its first project in Africa on April 13, 2016, and on August 17, 2017, the Bank opened its Africa Regional Centre (ARC) in Johannesburg, South Africa. This article assesses the NDB's presence in Africa. It addresses the following questions: what role is the NDB playing in Africa? What is the ARC and why was its created? How well have the NDB and the ARC been performing? Have they delivered on their intended purpose? If the NDB or the ARC have not performed as well as hoped, or expected, what has stood in their way? We assess the NDB and the ARC within the context of the general experience of some of the projects that the NDB has been financing in Africa and determine whether there are lessons that can help the NDB as it expands further into the continent. The main policy recommendation is that the ARC be strengthened in ways that enhance the NDB's transparency and make it a truly new type of multilateral development bank.
Mental health service use and cost by Australian women in metropolitan and rural areas
Authors: Dolja‐Gore Xenia , Depczynski Julie , Byles Julie , Loxton Deborah 
Published: December 2023

AbstractIntroductionThe use and costs of mental health services by rural and remote Australian women are poorly understood.ObjectiveTo examine the use of the Better Access Scheme (BAS) mental health services across geographical areas.DesignObservational epidemiology cohort study using a nationally representative sample of 14 247 women from the Australian Longitudinal Study on Women's Health born 1973–1978, linked to the Medical Benefits Schedule dataset for use of BAS services from 2006 to 2015. The number and cost of BAS services were compared across metropolitan and regional/remote areas for women using the mental health services.Findings31% of women accessed a BAS mental health service, 12% in rural populations. Overall, 90% of women with estimated high service need had contact with professional services (83% rural vs 92% metropolitan regions). Mean mental health scores were lower for women accessing a BAS service in remote areas compared with metropolitan, inner and outer regional areas (61.9 vs 65.7 vs 64.8 vs 64.2, respectively). Higher proportion of women in remote areas who were smokers, low/risky drinkers and underweight were more likely to seek treatment. Compared with metropolitan areas, women in inner, outer regional and remote areas accessed a lower mean number of services in the first year of diagnosis (6.0 vs 5.0 vs 4.1 vs 4.2, respectively). Actual mean overall annual costs of services in the first year of diagnosis were higher for women in metropolitan areas compared with inner, outer regional or remote areas ($733.56 vs $542.17 vs $444.00 vs $459.85, respectively).DiscussionWomen in rural/remote areas not accessing services need to be identified, especially among those with the highest levels of distress. In remote areas, women had greater needs when accessing services, although a substantial proportion of women who sought help through the BAS services lived in metropolitan areas.ConclusionRegardless of lower cost to services in rural/remote areas, geographic and economic barriers may still be major obstacles to accessing services.
Militant Research in the Housing Movement: The Community Action Tenants Union Rent Strike History Project
Authors: Tubridy Fiadh 
Published: December 2023

AbstractKnowledge generated by and with radical housing movements is necessary to achieve a more just housing system. This article analyses a militant research project involving collective investigation of the history of rent strikes in Ireland undertaken within the Community Action Tenants Union Ireland. Drawing on the tradition of workers’ inquiry, it explores the relationships between militant research, class composition, and radical history, and how collective investigation of housing movement history might contribute to contemporary organising. The article is based on both oral history and archival research as well as reflections on the research process. The analysis focuses on how the project has or might contribute to current organising efforts through lessons drawn from historical analysis and connections developed through the research process, while also identifying tensions between research and organising. Overall, it highlights the value of radical history research as a form of organising and strategy for political recomposition.
Letter: Estimating the incidence of HBsAg seroclearance after cessation of tenofovir and entecavir ‐ potential influence of censored observation
Authors: Tsai Ying‐Nan , Wu Jia‐Ling , Hsu Yao‐Chun 
Published: December 2023

LINKED CONTENTThis article is linked to Chen et al papers. To view these articles, visit https://doi.org/10.1111/apt.17602 and https://doi.org/10.1111/apt.17788
Editorial: Monitoring methotrexate polyglutamates in Crohn's disease—Authors' reply
Authors: van de Meeberg Maartje M. , Fidder Herma H. , de Jonge Robert , Bouma Gerd , Bulatović Ćalasan Maja 
Published: December 2023

LINKED CONTENTThis article is linked to van de Meeberg et al papers. To view these articles, visit https://doi.org/10.1111/apt.17719 and https://doi.org/10.1111/apt.17743
Online counter‐mobilisation via social media: Exploration of pro‐regime opinion leaders in Hong Kong under Chinese sovereignty
Authors: Kwong Ying‐ho 
Published: December 2023

AbstractThe literature has long recognised non‐democratic regimes that are increasingly using Internet manipulation to undermine the opposition. Apart from network control, content surveillance and paying for Internet commentators, the implications of the new trend of online counter‐mobilisation remain to be explored. By analysing 5124 YouTube videos of Hong Kong's Anti‐extradition Bill Protests, this study examines how pro‐regime opinion leaders counter‐mobilised pro‐regime contents and Internet users responded to their videos. The results indicate that the main concern of the pro‐regime opinion leaders was to (i) demobilise the protests, (ii) condemn opposition figures and (iii) show their support for the authorities. Users were mainly participative in videos related to (i) justify suppression, (ii) support for front‐line police officers against protesters and (iii) criticism of the opposition. These differences reflect the apparent asymmetry between opinion leaders, who provide more negative contents, and followers, who have better responses to positively framed contents. The findings further contribute to exploring the strategies of the pro‐regime counter‐framing to overcome the challenges of the opposition camp.
Magnolol supplementation alleviates diquat‐induced oxidative stress via PI3K–Akt in broiler chickens
Authors: Peng Wei‐Shi , Gao Ming , Yao Xiao‐Feng , Tong Yue‐Yue , Zhang Hai‐Han , He Xi 
Published: December 2023

AbstractThis experiment was conducted to investigate the effects of magnolol on the oxidative parameters and jejunum injury induced by diquat in broiler chickens. This test adopts a 2 × 2 factors design, a total of 288 one‐day‐old male AA broiler chicks randomly allocated to four groups, consisting of six replicates of 12 birds each, which was then denoted as CON group, diquat (DIQ) group (16 mg/kg BW diquat was injected into birds at the age of 21 days), magnolol (MAG) group (basic bird diet supplemented with 300 mg/kg magnolol), and MAG + DIQ group. At 21 days of age, broilers in the DIQ group and the MAG + DIQ group were intraperitoneally injected with 16 mg/kg BW diquat. Results showed that diet supplementing with MAG could alleviate the decrease of ADG to a certain extent after exposure to DIQ. Addition of magnolol to the diet alleviated the decrease of ADG during injection, antioxidant enzymes, and gene expression and increased the markers of oxidative damage induced by diquat induction. Magnolol supplement reversed the increase of apoptotic cells in the diquat‐induced chicken jejunum. RNA sequencing showed that PI3K–Akt, calcium, and NF‐kappa B signaling pathways were the main enrichment pathways between the DIQ group and the MAG + DIQ group. Our findings revealed that magnolol may improve antioxidant enzyme activity and expression of related genes through the PI3K–Akt pathway to alleviate oxidative stress.
Peer acceptance and rejection during secondary school: Do associations with subsequent educational outcomes vary by socioeconomic background?
Authors: Plenty Stephanie , la Roi Chaïm 
Published: December 2023

AbstractResearch shows that peer relationships are associated with students' school adjustment. However, the importance of advantageous and disadvantageous factors for students' educational outcomes may vary by socioeconomic positioning. Drawing on sociometric and register data from a nationally representative sample of Swedish youth (n = 4996, girls 50%; migration background 19%), this study asks if family socioeconomic status moderates associations between youth's peer relationships and their subsequent educational outcomes. Based on preregistered analyses, associations that peer acceptance and rejection at age 14–15 years share with school grades at ~16 years and completion of upper secondary school at ~20 years were tested. The findings showed that positive and adverse peer relationships are most consequential for the educational outcomes of socioeconomically disadvantaged youth.
The N400 is Elicited by Meaning Changes but not Synonym Substitutions: Evidence From Persian Phrasal Verbs
Authors: Stone Kate , Khaleghi Naghmeh , Rabovsky Milena 
Published: December 2023

AbstractWe tested two accounts of the cognitive process underlying the N400 event‐related potential component: one that it reflects meaning‐based processing and one that it reflects the processing of specific words. The experimental design utilized separable Persian phrasal verbs, which form a strongly probabilistic, long‐distance dependency, ideal for the study of probabilistic processing. In sentences strongly constraining for a particular continuation, we show evidence that between two low‐probability words, only the word that changed the expected meaning of the sentence increased N400 amplitude, while a synonym of the most probable target word did not. The findings support an account of the N400 in which its underlying process is driven by the processing of meaning rather than of specific words.
Impact of Share 35 liver transplantation allocation in Australia and New Zealand
Authors: Fink Michael A. , Gow Paul J. , McCaughan Geoffrey W. , Hodgkinson Peter , Chen John , McCall John , Jaques Bryon , Crawford Michael , Strasser Simone I. , Hardikar Winita , Brooke‐Smith Mark , Starkey Graham , Jeffrey Gary P. , Gane Ed , Stormon Michael , Evans Helen , Tallis Caroline , Byrne Amanda J. , Jones Robert M. 
Published: December 2023

AbstractPatients with high model for end‐stage liver disease (MELD) scores waiting for liver transplantation in Australia and New Zealand (ANZ) have had limited access to deceased donor livers and therefore binational sharing of livers, for patients with a MELD score ≥35 was introduced in February 2016. Waiting list mortality, post‐transplant outcomes and intention‐to‐treat survival were compared between patients whose MELD score reached 35 on the waiting list between October 2013 and April 2015 (Pre‐Share 35 group, n = 23) and patients who were Share 35 listed between February 2016 and May 2022 (Share 35 group, n = 112). There was significantly reduced waiting list mortality in share 35 listed patients in comparison to the pre‐Share 35 group (11.7% vs. 52.2%, OR .120 95% CI .044–.328, P < .001). Post‐transplant patient and graft survival were not significantly different between the groups (5‐year patient survival 82% vs. 84%, P = .991, 5‐year graft survival 82% vs. 76%, P = .543). Intention‐to‐treat survival was superior in the Share 35 group (HR .302, 95% CI .149–.614, P < .001). Introduction of Share 35 in ANZ resulted in a 78% risk reduction in waiting list mortality, equivalent post‐transplant survival and an improvement in intention‐to‐treat survival.