bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Intensity of Post-Vaccination Immunity to Hepatitis B among HIV-infected and Conditionally Healthy Persons in Western Siberia
Authors: Kartashov M. Yu. , Svirin K. A. , Krivosheina E. I. , Chub E. V. , Ternovoi V. A. , Kochneva G. V. 
Published: January 2024

Relevance. Hepatitis B often causes liver cirrhosis and hepatocellular carcinoma, especially among patients with HIV. Vaccination is the main prophylaxis of HBV for preventing infection and developing chronic disease. Studying the duration of postvaccination immunity and the expediency of revaccination in different age and risk groups is important for improving the strategy of immunoprophylaxis of B hepatitis.Aims. Study was to determine the level of post-vaccination immunity to HBV and specific antibodies (anti-HBc and anti-HBs) among HIV-positive patients and the healthy population of Novosibirsk and Tomsk.Materials and methods. 536 blood samples were taken from HIV-positive patients and 337 blood samples from healthy people (pregnant women and persons undergoing a routine medical examination). The presence of HBsAg, anti-HBs IgG, and anti-HBcIgG were determined in the samples.Results. The proportion of post-vaccination immunity decreased in older age groups with an increase in the proportion of post-exposure immunity. The proportion of HIV-positive patients who had contact with HBV was higher than among healthy people. Around 70% of people in each group had a low level of protective antibodies anti-HBs (lower than 100 IU). A high level of anti-HBs (higher than 400 IU) was determined in 10% of examined people. The proportion of low levels of anti-HBs increased with age, while average and high levels of post-vaccination immunity were less common with increasing age.Conclusion. A low proportion of HIV-positive people, who have been effectively vaccinated against hepatitis B, was noticed. Annual blood tests for the presence of HBsAg, anti-HBs, and anti-HBc, in combination with determining DNA HBV, can be recommended for HIV-positive patients who have a risk of developing an occult form of hepatitis B.
Formation of Genetically Determined Resistance against Human Norovirus Infection through Polymorphism of the FUT2 gene: a Review of the Literature
Authors: Bykov R. O. , Semenov A. V. , Starikova P. K. , Itani T. M. 
Published: January 2024

Relevance. Human Noroviruses (HuNoV) are highly contagious pathogens responsible of acute human norovirus infection. HuNoV is the cause of every fifth case of acute non-bacterial gastroenteritis, annually causing about 699 million cases of the disease and more than 200 thousand deaths worldwide. Controlled expression of the HBGA antigens by the FUT2 gene causes resistance to human norovirus. Polymorphisms of the FUT family genes contribute to partial or complete immunity to certain genogroups/ genotypes of norovirus.Aims. To characterize the effect of FUT2 gene polymorphisms on susceptibility to HuNoV.Results. Nonsensemutations of G428A in two homologous alleles contribute to the formation of a secretory-negative phenotype (se), which is a factor determining immunity to noroviruses. Some missense-mutations in the nucleotide positions se385,571 form partial resistance against certain genotypes. People with a secretory-negative phenotype are immune to infection by the GII.4 genotype and its genovariants.Conclusions. The expression of HLA antigens by the functionally inactive FUT2 gene plays a key role in the resistance of the human population to HuNoV. Susceptibility to HuNoV largely depends on the prevalence of HBGA phenotypic diversity among ethnic populations around the world. Targeted screening aimed at identifying polymorphisms of the FUT family will allow identifying risk groups more susceptible to HuNoV.
Analysis of the Causes and Conditions for the Formation of a High Incidence of Acute Respiratory Infections (ARI) in the Population of the Altai Krai (Part 1. Features of Long-Term and Intra-Annual Dynamics of ARI Incidence in 2011–2021)
Authors: Blokh A. I. , Pen`evskaya N. A. , Rudakov N. V. , Egorova O. F. , Manokhina Kh. A. , Abdrashitova L. V. , Saveliev D. A. 
Published: January 2024

Relevance. The Altai Krai (AK) is among the least prosperous subjects of the Russian Federation in terms of the incidence of acute respiratory infections (ARI).Aim: to analyze the causes and conditions for the formation of a high incidence of ARI among the population of the Altai Krai based on an assessment of the long-term and intra-annual dynamics of the epidemic process in 2011–2021.Materials and methods. In the course of a retrospective epidemiological study according to the annual forms No. 2 of the state statistical observation (SOS) for 2011-2021 a comparative analysis of the incidence of ARI and community-acquired pneumonia (CAP) in various groups of the population of the AK, the Siberian federal district (SFD) and the population of the Russian Federation as a whole was carried out. Data for 2020–2021 («covid» period) was analyzed separately in comparison with the precovid period of 2011–2019. The intra-annual dynamics of the incidence of ARI and CAP in the AK were studied using the method of trend-seasonal decomposition according to the monthly forms No. 2 of the SOS.Results and discussion. It is established that in 2011–2021. the epidemic process of ARI in the AK was characterized by a higher level and rate of increase in the incidence of all population groups (adults and children, urban and rural) compared to the all-Russian and average for the Siberian Federal District; a higher proportion of children in the overall structure of ARI cases, despite the fact that the proportion of the child population did not exceed (or was even less) than in other regions; no decrease in the incidence of ARI in children in the period 2020–2021; the presence of a trend towards an increase in the incidence of ARI in both urban and rural residents in the pre-covid period; higher incidence in the rural population in 2011–2019 compared to the whole of the Russian Federation or the Siberian Federal District. A less pronounced role of the seasonal component in the registration of CAP was revealed, in comparison with ARI. In some years, an increase in the registration of CAP was observed in the spring-summer period. For 2020-2021 there was a close coincidence of the curves of the intra-annual dynamics of the registered incidence of ARI and COVID-19 among the general population, CAP and COVID-19.Conclusion. The obtained results indicate the need to study the possible impact of environmental factors, as well as the shortcomings of the etiological interpretation and differential diagnosis of some natural focal and zoonotic infections that occur with fever and respiratory symptoms on the formation of a high incidence of ARI in the Altai Territory.
The effect of Locally Applied Bacillus safensis Strain 440-1 from Antarctic Soil on the Course of Experimental Wound Staphylococcal Infection
Authors: Aslanov B. I. , Kolodzhieva V. V. , Lebedeva E. A. , Tumanyan I. A. , Won Yu. D. , Mokhov A. S. , Dolgiy A. A. , Goncharov A. E. 
Published: January 2024

Relevance. Infections caused by methicillin-resistant strains of Staphylococcus aureus are an urgent problem of hospital epidemiology, and control measures involve the development of new antimicrobials. Probiotics based on bacterial strains isolated fro natural habitats are considered promising means of combating MRSA.Aims. To test the possibility of using the Bacillus safensis 440-1 strain isolated from Antarctic soil. as an antibacterial agent for the treatment of experimental staphylococcal infection.Purpose of the study – check the possibility of using the Bacillus safensis 440-1 strain, isolated from Antarctic soil, as a topical antibacterial agent for the treatment of experimental staphylococcal infection.Material and methods. The potential virulence of Bacillus safensis strain 440-1 was studied on a mouse peritonitis model, and its activity against the methicillin-resistant Staphylococcus aureus SA776 test strain was studied on a localized wound infection model.Results and discussion. Our study demonstrated the safety of the tested strain due intraperitoneal use. We found that the use of the studied strain reduces the staphylococci amount in wounds from the third day from the start of the study to the end of the observation period, without aggravating the course of the infection.Conclusion. Bacillus safensis strain is a promising potential probiotic and it can be used as a part of complex antiseptic or disinfectant after additional studies aimed at developing an optimal mode of its use.
Immunological Efficacy of Vaccination against COVID-19 in Employees of Medical Institutions of Various Profiles: Psychiatric Hospital and Regional Hospital
Authors: Murzina A. A. , Zubkov A. V. , Svitich O. A. , Kaira A. N. 
Published: January 2024

Relevance. On the territory of the Russian Federation, mass vaccination of the population is recognized as a priority health strategy against COVID-19, Gam-COVID-Vac vaccine has been widely used. The main risk group, which is subject to priority vaccination, are employees of medical organizations (MO). The determination of IgG to SARS-CoV-2 is an important parameter for assessing the intensity and duration of post-vaccination immunityAims. Study the immunological efficacy of the vaccine Gam-COVID-Vac used by employees of a psychiatric hospital and a regional hospital.Materials and methods. A study of the blood sera of 410 employees of two MO of various profiles who received one full course of the Gam-COVID-Vac» vaccine for the presence of IgG to RBD Spike SARS-CoV-2 using a set of reagents «SARS-CoV-2-IgG quantitative-ELISA-BEST» and IgG to NC SARS-CoV-2 using a set of reagents «ELISA anti-SARS-CoV-2 IgG».Results and discussion. Specific IgG to RBD Spike SARS-CoV-2 after vaccination with «Gam-COVIDVac » were found in 92.9% of psychiatric hospital staff and 98.0% of the regional hospital. Antibodies of class G to SARS-CoV-2 with a level of 300 BAU/ml or more were detected in 11.6% of psychiatric hospital staff and in 70.0% of regional hospitals, which is associated with the smallest proportion of persons in a psychiatric hospital with hybrid immunity than in a regional hospital (67.4% vs. 89.0%, respectively). A study of employees of the Ministry of Defense of various profiles revealed a difference in the level of IgG to RBD Spike SARS-CoV-2: 178.0 BAU/ml in a psychiatric hospital and 366.0 BAU/ml in a regional hospital. In a psychiatric hospital, the IgG level was highest up to 3 months after the completed vaccination – 166.4 BAU/ml, in a regional hospital from 3 to 6 months – 362.8 BAU/ml, then the number of antibodies decreases, which indicates the importance of monitoring for class G antibodies to SARS-CoV-2 at different times after vaccinations. Among the employees of the two MO, mild forms of the COVID-19 disease prevailed.Conclusion. Thus, the high immunological effectiveness of vaccination against COVID-19 with Gam-COVID-Vac was established in a group of employees of two MO, and the need for serological monitoring for the purpose of revaccination was also shown.
Geosteering, application of synthetic logging to horizontal wellbore sections
Authors: Novitskaya E. V. , Shiryaev A. A. 
Published: January 2024

This article provides an analysis of the process and optimization of horizontal wellbore tracking using geosteering control. Recently, the issue of high-quality and efficient drilling of wells through the reservoir and determining the position of the wellbore in the formations has been raised. In this regard, complex data analysis is used based on a 3D geological model and special software for well geosteering. In preparation for drilling a well, it is necessary to prepare voluminous, comprehensive information on previously drilled wells in a particular field and upload the results of seismic surveys. The article also describes an analysis of activities at various stages of drilling support, starting with geophysical reference and opening the target formation with the transport section. When drilling a horizontal section of a well, geosteering software is used while drilling wells, equipped with various tools, one of which is the 2D synthetic logging method. The method is based on the superposition of logging curves of a previously drilled reference vertical well and a directional well with a horizontal end currently being drilled. The two-dimensional synthetic logging method is the main and most optimal way to optimize the placement of wells with horizontal completion when drilling terrigenous reservoirs in Western Siberia.
Pengaruh Citra Merek Dan Harga Terhadap Keputusan Pembelian Pada E-Commerce Shopee
Authors: Hatta Pinasthika Al Shifa , Alam Iskandar Ali 
Published: January 2024

This research was conducted to analyze the effect of brand image and price on the purchasing decisions of Shopee Indonesia customers. This type of research is quantitative. The number of samples in this study amounted to 107 respondents with a non-probability sampling technique with a purposive sampling approach. Data collection was carried out by distributing questionnaires that had been tested for validity and reliability. Respondents in this study were students of management class 20 at the University of Bandar Lampung. This research uses multiple linear regression analysis. The research results show that brand image has a significant influence on purchasing decisions, then price has a significant influence on purchasing decisions, and brand image and price together have a significant influence on purchasing decisions.
Keywords: Brand Image; Price; Purchase Decision
Experience of using the visualized programming environment Scratch for teaching the basics of algorithmization and programming in grades VI—VIII in schools of Belarus
Authors: Frantskevich A. A. , Prostak O. Yu. 
Published: January 2024

"Algorithmization and programming" is an important content line of the school informatics course. However, many students have difficulty learning it due to insufficient development of abstract thinking and lack of practical experience in programming. The visual programming language Scratch can become a propaedeutic tool for studying this content line, allowing one to overcome these difficulties and make the study of programming more accessible and interesting for schoolchildren.The article presents examples of tasks to be performed in the visualized programming environment Scratch, which are offered to students of the VI—VIII grades of schools in Belarus to master the content line "Fundamentals of algorithmization and programming" of the academic subject "Informatics". Each task is presented at three levels: reproductive, productive and creative.The material will be useful to informatics teachers working with students who find it difficult to master the concepts of algorithmization and programming using text-based programming languages (Pascal, Python, C++, etc.).
Sosialisasi SOSIALISASI PEMBUATAN NIB DALAM RANGKA PENGEMBANGAN UMKM DI LAPANGAN GEMEK, KECAMATAN KEDUNGWUNI, KABUPATEN PEKALONGAN
Authors: Ulfiana Hilda , Febriana Riski , Amanah Khorissatul 
Published: January 2024

ABSTRACT
Gemek Kedungwuni Field, located in front of SMA 1 Kedungwuni, Pekalongan Regency, is a large public area with a number of MSMEs actively selling in it. Unfortunately, most of them have yet to complete their business legality in the form of a Business Identification Number (NIB) and Halal certificate. Many businesses feel that the process of obtaining these documents is complicated and time-consuming. In order to support the development of micro, small and medium enterprises (MSMEs) in Indonesia, assistance with NIB registration and socialization of the importance of halal certificates is a very important step. The main objective of this activity is to increase the understanding and awareness of MSME players regarding NIB registration procedures and the urgency of halal certification in expanding market share. The methods applied include observation, counseling, and direct assistance to MSME players in the field. It is hoped that the results of this activity can increase the number of registered MSMEs and obtain halal certificates, and make a positive contribution to improving the overall quality of MSME products. The conclusion of this activity indicates that NIB assistance and halal certificate socialization have a significant positive impact in advancing the MSME sector in Indonesia.
REGULASI DIRI DAN KECENDERUNGAN ADIKSI INSTAGRAM PADA MAHASISWA PENGGUNA INSTAGRAM DI UNIVERSITAS X
Authors: Paramesti Anidiah , Purnamasari Ayu , Juniarly Amalya 
Published: January 2024

ABSTRAK
Tujuan penelitian ini adalah untuk mengetahui hubungan antara regulasi diri dan kecenderungan adiksi Instagram pada mahasiswa pengguna Instagram di Universitas Sriwijaya. Hipotesis dari penelitian ini adalah ada hubungan antara regulasi diri dengan kecenderungan adiksi Instagram di Universitas X.
Subjek penelitian adalah 160 mahasiswa Universitas X yang aktif menggunakan Instagram setiap hari dan menghabiskan waktu 5 jam hingga lebih dalam sehari. Kecenderungan adiksi Instagram diukur dengan skala baku Test for Instagram Addiction (TIA) yang dibuat oleh D'Souza, Samyukta, dan Bivera (2019) dan regulasi diri dukur dengan skala baku The Self-Regulation Questionnaire (SRQ) yang dibuat oleh Brown, Miller, & Lawendowski (1999). Hasil data penelitian dianalisis dengan menggunakan metode korelasi Spearman.
Hasil penelitian menunjukkan ada hubungan ada hubungan antara regulasi diri dan kecenderungan adiksi Instagram pada mahasiswa pengguna Instagram di Universitas X dengan nilai r = -0,460, dan p = 0,000 (p<0,05). Hal ini menunjukkan bahwa regulasi diri memiliki hubungan yang sedang, negatif, dan signifikan dengan kecenderungan adiksi Instagram. Dengan demikian hipotesis penelitian yang diajukan dapat diterima.
Kata Kunci: Regulasi diri, Kecenderungan Adiksi Instagram

ABSTRACT
This research aims to know the relationship between self-regulation and tendency of Instagram addiction in Instagram users at X University. This hypothesis was there is relationship between. Self-regulation and tendency of Instagram addiction in Instagram users at X University.
The subject was 160 X University student who actively using Instagram every day and spend 5 hours to more for a day. Tendency of Instagram addiction was measured by Test for Instagram Addiction (TIA) scale from D'Souza, Samyukta, dan Bivera (2019) and self-regulation measured by Self-Regulation Questionnaire (SRQ) from Brown, Miller, & Lawendowski (1999). Data analysis using simple correlation Spearman analysis.
The result of the correlation Spearman showed that there is relationship between self-regulation and tendency of Instagram addiction in Instagram users at X University with value of r = -0,460, and p = 0,000 (p<0,05). It shows that self-regulation has moderate, negative, and significant relationship with tendency of Instagram addiction. Thus the hypothesis in this research was accepted.
Keyword: Self-regulation, Tendency of Instagram addiction
Job Insecurity dan Keterlibatan Kerja pada Karyawan Outsourcing
Authors: Vini Alamanda Putri  , Pratiwi Marisya , Puspasari Maya 
Published: January 2024

Tujuan penelitian ini adalah untuk mengetahui hubungan antara job insecurity dengan keterlibatan kerja pada karyawan outsourcing di PT. KAI Palembang. Hipotesis dari penelitian ini adalah ada hubungan antara job insecurity dengan keterlibatan kerja pada karyawan outsourcing di PT. KAI Palembang.
Subjek penelitian adalah karyawan outsourcing di PT. KAI Palembang yang berjumlah 115 orang. Job insecrurity dan keterlibatan kerja diukur dengan skala job insecurity dan keterlibatan kerja dengan berlandaskan dimensi job insecurity dari Dachapalli dan Parumasur (2012) dan dimensi keterlibatan kerja dari Yoshimura (1996). Hasil data penelitian dianalisis dengan menggunakan metode korelasi Spearman.
Hasil penelitian menunjukkan ada hubungan antara job insecurity dengan keterlibatan kerja pada karyawan outsourcing di PT. KAI Palembang dengan nilai r = -0,838, dan p = 0,000 (p<0,05). Hal ini menunjukkan bahwa job insecurity memiliki hubungan yang sangat kuat, negatif, dan signifikan dengan keterlibatan kerja. Dengan demikian hipotesis penelitian yang diajukan dapat diterima.
REGULASI EMOSI DAN PEMAAFAN PADA DEWASA AWAL KORBAN PERSELINGKUHAN
Authors: Febriyanti Atikah , Juniarly Amalia 
Published: January 2024

Abstrak. Penelitian bertujuan untuk mengetahui hubungan antara regulasi emosi dengan pemaafan pada dewasa awal korban perselingkuhan di kota Palembang. Hipotesis penelitian yaitu ada hubungan antara regulasi emosi dengan pemaafan pada dewasa awal korban perselingkuhan di kota Palembang. Populasi penelitian adalah dewasa awal di kota Palembang korban perselingkuhan dalam relasi romantis, dengan jumlah tidak diketahui. Sampel penelitian sebanyak 100 orang dan untuk uji coba sebanyak 50 orang, diambil melalui teknik purposive sampling. Alat ukur penelitian mengunakan skala pemaafan mengacu pada dimensi-dimensi pemaafan dari Baumeister, Exline, dan Sommer (1998); skala regulasi emosi mengacu pada aspek-aspek regulasi emosi dari Gross dan Thompson (2007). Analisis data penelitian menggunakan korelasi Pearson’s Product Moment. Hasil analisis korelasi menunjukkan bahwa regulasi emosi memiliki hubungan yang signifikan dengan pemaafan, nilai p=0,012 (p<0,05) dan r= 0.250. Dengan demikian, hipotesis yang diajukan diterima.
Kata kunci: Regulasi Emosi, Pemaafan.
Abstract. The research objective was to determine the relationship between emotion regulation with forgiveness in early adults, the victim of infidelity at Palembang city. The hypothesis of this research has a relationship between emotion regulation with forgiveness in early adults, the victim of infidelity in Palembang city. The research population were early adults at Palembang city, the victim of infidelity in romantic relationship, with unknown population. The research sample were 100 people and for try out were 50 people, taken by purposive sampling technique. The research measurement instruments used forgiveness scale that referring to dimensions of forgiveness from Baumeister, Exline, and Sommer (1998); emotion regulation scale that referring to aspects of emotion regulation from Gross and Thompson (2007). The data analysis used Pearson’s Product Moment correlation. The result of correlation analysis showed that emotion regulation has a significant relationship with forgiveness, p-value=0,012 (p<0,05) and r=0.250. Therefore, the proposed hypothesis is accepted.
Keywords: Emotion Regulation, Forgiveness.