bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medical Ozone Treatment Alleviate Blood Oxidative Stress And Pancreas Damage In an Alloxan-Induced Diabetes Model in Rats
Authors: Falih Shaymaa , Bushra F. HASAN  
Published: December 2023

Diabetic mellitus (DM ) is a prevalent systemic disease affecting a human and animals. The effects of diabetes are devastating and well documented. The increased production and/or ineffective scavenging of reactive oxygen species (ROS) may play a critical role in the development of diabetic complications. Therefore, it seems reasonable that antioxidants can play an important role in the improvement of diabetes. So, use medical ozone to study if it can regulate the oxidative complications of DM .The study was carried out on forty eight albino females rats included six groups Group I (Control) : 8 female rats were injected IP with citrate buffer (0.1 M, pH 5) daily for 6 weeks ,Group II (MO ): 8 female rats were injected IP 1.1 mg/kg b.w of MO daily for 6 weeks ,Group III (DM): 8 female rats induce diabetes by injection IP with freshly prepared alloxan 150 mg/kg b.w in citrate buffer (pH 5), Group IV(DM+MO): 8 diabetic female rats were injected IP 1.1 mg/kg b.w of MO daily for 6 weeks, group V(DM + Insulin): 8 diabetic female rats were injected subcutaneously 0.75 IU/100 g b.w. of Insulin daily for 6 weeks ,Group VI(DM +MO +Insulin):8diabetic female rats were injected IP 1.1 mg/kg b.w of MO and Insulin injected subcutaneously at a dose of 0.75 IU/100 g b.w , respectively daily for 6 weeks. experimental study parameters include antioxidant enzymes assay and histology the study for pancreas.
Estimation of NLRP3 Inflammasome Role and some Biochemical Parameters in Patients with Chronic Kidney Diseases (CKD)
Authors: Faraj Hadeel , Nada Hussain Alwan  
Published: December 2023

Chronic kidney disease (CKD) is a widespread condition that poses a major threat to human health. With substantial public health costs, severe morbidity, and mortality, CKD prevalence is increasing. The study aimed to look at NLRP3 inflammasome , hsCRP , Urea , Creatinine, Uric acid and GFR levels. Serum NLRP3 inflammasome , hsCRP , Urea , Creatinine, Uric acid and GFR levels were determined in 90 patients with Chronic Kidney Diseases (CKD) , and 85 healthy subjects, an age range (30-75). The results of current study show a significant increase in the concentration of serum NLRP3 inflammasome, hs-CRP, urea , creatinine and uric acid in (CKD) patients group in comparison with controls group (p<0.05). While shows a significant decrease in GRF in (CKD) patients group in comparison with controls group (p<0.05). The aim of this study is estimated the NLRP3 inflammasome , Inflammation marker , kidney function tests and Glomerular filtration rate (GFR) in patients with Chronic Kidney Disease.
O QUE DIZEM OS DISCURSOS OFICIAIS PROFERIDOS PELO EX-PRESIDENTE DO BRASIL, JAIR BOLSONARO, DURANTE O ENFRENTAMENTO DA COVID-19 NO PAÍS
Authors: SILVA Thaís Ohanna de Oliveira , Rosana de Araujo Oliveira Sydia 
Published: December 2023

Introdução: Em dezembro de 2019, na China, emergiu o novo coronavírus (SARS-CoV-2), causador da pandemia da Covid-19, e, desde então, uma preocupante crise sanitária tem assolado o mundo. A pandemia decretada exigiu dos governantes uma resposta rápida e eficiente à disseminação da doença, de forma a evitar o adoecimento na sua forma mais grave e, consequentemente, muitas mortes. Objetivo: Analisar os discursos oficiais proferidos pelo ex-presidente do Brasil, Jair Bolsonaro, durante o enfrentamento da Covid-19 no país. Método: Foram identificados 13 discursos, os quais foram analisados utilizando-se como base o método da Análise de Conteúdo. Os dados foram organizados em 4 categorias empíricas. Resultados: O ex-presidente desestimulou a adoção de medidas sanitárias necessárias ao enfretamento da pandemia; priorizou a economia em detrimento da saúde; minimizou o impacto da doença e defendeu a volta ao estado de normalidade; criticou a atuação dos demais entes governamentais e se desresponsabilizou pelos efeitos negativos da pandemia; assim como promoveu o uso de medicamentos sem eficácia comprovada. Conclusão: Em meio a uma das maiores crises sanitárias já enfrentadas pelo país, a vida e a saúde do povo não foram prioridade.
PALABRAS-CHAVE:Covid-19. Pandemias. Cloroquina. Políticas Sanitárias. Discurso Público.
UMA PROPOSTA DE MENSURAÇÃO SENIANA DA POBREZA MULTIDIMENSIONAL NA CIDADE DO RECIFE
Authors: Melo Ielyson José Rodrigues de , Monteiro Costa Ana 
Published: December 2023

Este trabalho apresenta um breve histórico acerca da pobreza, enfatizando o debate entre o seu caráter uni e multidimensional, com destaque à abordagem seniana, que trata o tema não como a privação de um determinado nível de renda, mas como a privação de capacitações, ou seja, da liberdade de ser e agir conforme se considere digno. Neste sentido, foram analisadas as questões socioeconômicas no Recife, onde foi possível observar uma desigualdade de renda extremamente elevada contrastando com um Índice de Desenvolvimento Humano médio-alto. Isso é explicado pela distância social existente entre algumas Unidades de Desenvolvimento Humano (UDHs), que estão bem próximas a de países de Índice de Desenvolvimento Humano (IDH) alto, como a Noruega, e outras que estão mais próximas dos países de IDH mais baixo, como os mais pobres da África subsaariana. Dito isto, este trabalho teve como questão fundamental apresentar o método Alkire-Foster para medir a pobreza multidimensional no Recife. Essa proposta de operacionalização da abordagem das capacitações visa compreender as privações que a população recifense sofre e que não são captadas pela análise estritamente monetária. Para tanto, incorporam-se variáveis como educação, saúde, condições de habitação, etc, dando atenção à heterogeneidade existente entre os seres humanos.
PALAVRAS-CHAVE: Pobreza multidimensional. Abordagem seniana. Recife.Método Alkire-Foster.
ESCOLAS DE TEMPO INTEGRAL EM PERNAMBUCO
Authors: Barbosa Ingrid , Lima Ytalo , Maria Lima Rodrigues Cibele 
Published: December 2023

O artigo discute a concepção curricular que está presente no Programa das Escolas de Referência de Pernambuco, cujo objetivo é a implantação de escolas de ensino médio em tempo integral. Ele abrange cerca de 40% (463) escolas da rede estadual. Como recurso metodológico foi realizado o levantamento bibliográfico que culminou na identificação e análise de doze trabalhos acadêmicos (teses e dissertações). Fizemos uma classificação que distingue entre perspectivas otimistas (funcionalistas e da teoria do capital humano) e abordagens críticas (marxistas). No primeiro grupo, elogiam o Programa pela gestão de resultados e por desenvolver competências dos indivíduos para se inserirem no mercado de trabalho, seguindo uma cultura empresarial. Por outro lado, os trabalhos marxistas apontam as contradições de uma formação que se diz integral, mas se restringe a contribuir com a reprodução do capitalismo.
PALAVRAS-CHAVE: Educação. Escola em tempo integral. Ensino Médio. Pernambuco.
NOTA EDITORIAL
Authors: Pessoa de Arruda Raposo Isabel , Maria Lima Rodrigues Cibele , Da Mota Távora Luciana Elizabeth 
Published: December 2023

É com satisfação que encerramos o ano de 2023 com a publicação do segundo número da edição semestral da Revista Cadernos de Estudos Sociais. Essa edição, de fluxo contínuo, apresenta seis artigos de temáticas diversas das ciências sociais e humanidades. Com a valiosa ajuda dos pareceristas ad hoc e dos autores, conseguimos manter a revista atualizada e com um número crescente de submissões.
Theory and Practice: A Path from ENERPO Graduate to Lead Surveillance Analyst at a Commodities Futures Exchange
Authors: Roh M. , Mironova I. 
Published: December 2023

In today’s changing international environment, it is important for young specialists to find their place in the professional world. Education is a cornerstone of this process, so the ENERPO educational program helps students pave their way for a successful career in the energy sector. This is an interview with Michael Roh, an ENERPO graduate now working as a lead surveillance analyst at a commodities futures exchange.
В сегодняшней изменчивой международной обстановке молодым специалистам важно найти своё место в профессиональном мире. Образование является краеугольным камнем этого процесса, поэтому образовательная программа ЭНЕРПО помогает студентам проложить путь к успешной карьере в энергетическом секторе. Данная статья представляет собой интервью с Майклом Ро, выпускником ЭНЕРПО, который в настоящее время является ведущим аналитиком биржи товарных фьючерсов.
PENGEMBANGAN MEDIA ARTICULLATE STORYLINE 3 BERBASIS SAINTIFIK PADA PEMBELAJARAN TEMATIK TERPADU DI KELAS III SEKOLAH DASAR
Authors: Anggraini Tri Suci , Reinita  
Published: December 2023

This research is motivated by the use of learning media which only focuses on the use of textbooks in the delivery of learning materials, and the use of technology as a learning medium in learning activities is still rarely used. The purpose of the research was to develop a scientific based Articulate Storyline 3 media in integrated learning in the third grade of elementary school.The type of research used is research an development (R&D) research or development research. The model used in this study is the ADDIE model. The ADDIE model has five stages in its development, namely Analysis, Design, Development, Implementation, and Evaluation.The results of this study stated that the use of scientific based Articulate Storyline 3 learning media obtained a valid category with the results of material validation 83.95%, media validation 76.6% and language validation 82%. the result of the practicality test are stated to be very practical. This is obtained from the teacher response questionnaire and the student response questionnaire for class III SD Negeri 02 Jambak Lubuk Sikaping attitude where the results obtained are 88.6% student response questionnaires. Thus, the scientific based Articulate Storyline 3 learning media in integrated thematic learning in grade III elementary school is declared valid and very practical.
PENGARUH PENERAPAN MODEL PROBLEM BASED LEARNING TERHADAP HASIL BELAJAR SUBTEMA BANGGA TERHADAP DAERAH TEMPAT TINGGALKU
Authors: Amalia Intan , Muhajang Tatang , Hikmah Nur 
Published: December 2023

Penelitian ini adalah penelitian eksperimen quasi. Penelitian ini bertujuan untuk mengetahui pengaruh model Problem Based Learning terhadap hasil belajar subtema bangga terhadap daerah tempat tinggalku. Penelitian ini dilaksanakan di Sekolah Dasar Negeri Cimanggis 02 Kabupaten bogor Kelas IV A, san IV B pada bulan Mei sampai semester genap. Perhitungan N-Gain model Problem Based Learning sebesar 70 dengan kiteria tinggi dan ketuntasan hasil belajar 83%, nilai N-Gain model konvensional sebesar 37 dengan kriteria sedang dan ketuntasan hasil belajar 70%. Hasil pengujian hipotesis menyatakan bahwa H0 ditolak dan Ha diterima, karena hasil perhitungan thitung (5,8718) > ttabel (2,00172). Berdasarkan hasil penelitian, disimpulkan bahwa terdapat pengaruh dari penggunaan model Problem Based Learning terhadap hasil belajar subtema bangga terhadap daerah tempat tinggalku. Model pembelajaran yang sangat efektif untuk digunakan pada subtema bangga terhadap daerah tempat tinggalku yaitu model Problem Based Learning.
Kata Kunci: Problem Based Learning, Hasil Belajar.
Increasing Mathematical Logic Intelligence Through Problem Based Learning Learning Models in Grade 1 Elementary School Students
Authors: Sari Hayati Yulia Lisa , Anggarini Vina , Yayuk Erna 
Published: December 2023

Kecerdasan logis matematis merupakan kemampuan yang penting untuk dimiliki agar dapat berpikir secara logis dalam memecahkan kasus atau permasalahan sehari-hari yang berhubungan dengan perhitungan matematis. Maka dalam penanaman kecerdasan logis matematis diperlukan stimulus permasalahan kontekstual melalui penerpan model pembelajaran Problem Based Learning (PBL). Penelitian ini bertujuan untuk menjelaskan penerapan model Problem Based Learning (PBL) dalam menanamkan kecerdasan logis matematis pada siswa sekolah dasar. Metode penelitian ini ialah penelitian tindakan kelas (PTK), dengan pelaksanaan penelitian sebanyak dua siklus. Tahapan dalam penelitian ini yaitu: (1) Planning, (2) Acting and Observing, (3) Reflecting. Hasil penelitian menunjukkan peningkatan kecerdasan logis matematis pada siswa kelas 1 SD Negeri Balung Jeruk melalui penerapan model pembelajaran Problem Based Learning (PBL). Tahap pra-siklus menunjukkan kemampuan kecerdasan logis matematis sebesar 19%. Siklus I menunjukkan peningkatan kemampuan kecerdasan logis matematis sebesar 11% sehingga menjadi 30%. Siklus II menunjukkan kemampuan kecerdasan logis matematis sebesar 12% sehingga menjadi 52%.
Prevalence and factors associated with restless legs syndrome among pregnant women in middle-income countries: a systematic review and meta-analysis
Authors: Mislu Esuyawkal , Assalfew Betel , Arage Mulugeta Wodaje , Chane Fiker , Hailu Tilahun , Tenaw Lebeza Alemu , Kidie Atitegeb Abera , Kumsa Henok 
Published: December 2023

IntroductionRestless legs syndrome (RLS) is a debilitating condition characterized by uncomfortable sensations in the legs, typically occurring during periods of rest or sleep. It is more prevalent during pregnancy and is linked to sleep disturbances, diminished quality of life, and pregnancy complications. However, previous studies yielded inconsistent findings among pregnant women in middle-income countries. Consequently, this systematic review and meta-analysis sought to determine the pooled prevalence of restless legs syndrome and its associated factors in these populations.MethodA systematic review and meta-analysis was conducted on published studies from middle-income countries until May 2023. The review strictly adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant search terms were used to search for studies in PubMed, MEDLINE, EMBASE, and Google Scholar. Data extraction was performed using the Joanna Briggs Institute tool for prevalence studies. The meta-analysis was conducted using STATA 17 software, and heterogeneity was assessed using the I2 test, while publication bias was evaluated using Egger's test. Forest plots were also used to present the pooled prevalence and odds ratio (OR) with a 95% confidence interval (CI) using the random-effects model.ResultThis review included 22 studies from nine countries with a total of 17, 580 study participants. The overall pooled prevalence of RLS among pregnant women in middle-income countries was 13.82% (95% CI: 13.31, 14.32), and having low hemoglobin level (AOR: 1.68, 95% CI: 1.29, 2.18), history of RLS (AOR: 7.54, 95% CI: 3.02, 18.79), muscle cramps (AOR: 3.58, 95% CI: 1.21, 10.61), excessive day time sleepiness (AOR: 4.02, 95% CI: 1.34, 12.04), preeclampsia (AOR: 2.06, 95% CI: 1.28, 3.30), and taking prophylactic iron supplementation (AOR: 0.59, 95% CI: 0.50, 0.69) were the identified factors associated with it.ConclusionGenerally, nearly one in every eight pregnant women in middle-income countries develop restless legs syndrome during pregnancy. Having low hemoglobin level, a history of RLS, muscle cramps, excessive daytime sleepiness, preeclampsia, and taking prophylactic iron supplementation were the identified factors associated with it. These findings underscore the importance of addressing the identified factors associated with RLS in order to effectively mitigate its occurrence among pregnant women.
Protective and risk factors associated with substance use coping among healthcare workers during the COVID-19 pandemic
Authors: Bryant Vaughn E. , Sorna Michael J. , Dana Audrey , Leon Kalie G. , Guastello Andrea D. , Sambuco Nicola , Huxhold Ashley , Allen Brandon , Cuffe Steven P. , Mathews Carol A. , Dale Lourdes P. 
Published: December 2023

BackgroundHealthcare workers (HCWs) experienced high levels of stress and mental health consequences associated with the COVID-19 pandemic, which may have contributed to unhealthy coping behaviors, such as substance use coping (SUC). This study aimed to understand the extent of and predictors of SUC.MethodsThe sample consisted of 263 HCWs in North Central Florida. Univariable and multivariable logistic regression analyses investigated whether moral injury and other work risk factors, protective factors, and clinically relevant symptoms (i.e., work exhaustion, interpersonal disengagement, depression, anxiety, and/or PTSD) were associated with likelihood of SUC.ResultsClinically relevant levels of interpersonal disengagement and anxiety increased the likelihood of SUC. Mediational analyses found that interpersonal disengagement and anxiety explained 54.3% of the relationship between Self Moral Injury and SUC and explained 80.4% of the relationship between professional fulfillment and SUC.ConclusionHealthcare supervisors should be aware that providers who are experiencing moral injury and less professional fulfillment may be experiencing significant interpersonal disengagement and anxiety, which could lead to SUC. Future studies should examine the effects of implementing targeted prevention and treatment interventions, along with longitudinal outcomes related to SUC behaviors.
ПРОБЛЕМНІ ПИТАННЯ КРИМІНАЛЬНОЇ ВІДПОВІДАЛЬНОСТІ ЗА ПОРУШЕННЯ НЕДОТОРКАННОСТІ ЖИТЛА, А ТАКОЖ ВЧИНЕННЯ ЦИХ ДІЯНЬ СЛУЖБОВОЮ ОСОБОЮ: НАЦІОНАЛЬНЕ ТА МІЖНАРОДНЕ ЗАКОНОДАВСТВО
Authors: Кришевич О. 
Published: December 2023

Недоторканність житла особи є принципом, визнаним світовою спільнотою. При здійсненні своїх прав і свобод кожна людина може зазнаватитільки таких обмежень, які встановлені законом виключно з метою забезпечення належного визнання і поваги до прав і свобод інших та забезпеченнясправедливих вимог моралі, громадського порядку і загального добробуту вдемократичному суспільстві (пункт 2 статті 29 Загальної декларації прав людини 1948 року, стаття 18 Конвенції про захист прав людини і основоположних свобод 1950 року (постанова Верховного Суду, справа №757/41727/19-цвід 12.03.2020). Зокрема, ст. 12 Загальної декларації прав людини, яка прийнята і проголошена резолюцією 217 А (III) Генеральної Асамблеї ООН від 10грудня 1948 р., передбачено: «Ніхто не може зазнавати безпідставного втручання у його особисте і сімейне життя, безпідставного посягання на недоторканність його житла... Кожна людина має право на захист закону від такого втручання або таких посягань». Аналогічна вимога міститься в ст. 17 Міжнародного пакту про громадянські і політичні права, прийнятого ГенеральноюАсамблеєю ООН 16 грудня 1966 р., який набув чинності для України 23 березня 1976 р. Гарантія недоторканності житла встановлена ст. 30 Конституції України [1], ст. 311 Цивільного кодексу України [6] та ст.ст. 7, 13, 233 Кримінального процесуального кодексу України [4]. В Конституції та інших законах не передбачено право будь-кого і будь-коли проникати в житло чи інше володіння особи тільки тому, що там хтось незаконно перебуває та володіє ним, окрім невідкладних випадків, зазначених у ч. 2 ст. 30 Конституції.
Çocuk Yoğun Bakım Ünitesi'nde Perfüzyon İndeksi Kullanımı ve Klinik İzlemleri
Authors: TALAY Mehmet Nur , ORHAN Özhan 
Published: December 2023

Amaç: Çocuk Yoğun Bakım Ünite’sinde (ÇYBÜ) invaziv olmayan ölçümler, hastaların hemodinamik izlemlerinde standart yöntemler olarak kullanılmaktadır. Bu çalışmanın amacı, ÇYBÜ’sinde takip edilen kritik hastalarda non-invaziv bir belirteç olan perfüzyon indeksinin (PI) kullanılabilirliğini araştırmak, diğer vital bulgularla karşılaştırmak ve mortaliteyi öngörmede kullanılabilirliğini analiz etmektir.
Yöntem: 01.Haziran.2018 – 31.Aralık.2019 tarihleri arasında yoğun bakımda izlenen 1 ay-18 yaş arası dolaşım bozukluğu olan kritik hasta çalışmaya dahil edildi. Hastaların yoğun bakıma alındıktan sonraki ilk 6 saat içinde PI, vital bulguları ve mortalite skorları karşılaştırıldı.
Bulgular: 0.saat değerleri incelendiğinde dehidratasyon-akut gastroenterit ve metabolik hastalık grubunda olanların PI değerleri düşük, kapiller dolum zamanı (KDZ) uzun ve laktat düzeyleri yüksek izlendi. Hastalar dehidratasyon bulgusu olan ve olmayan şeklinde gruplandırıldı. Dehidratasyon bulgusu olan hasta grubunda 0.saat PI ile KDZ, sistolik kan basıncı ve laktat düzeyleri arasında korelasyon analizinde; orta düzeyde (sırasıya r=-0,53/0,11/-0,36) negatif yönde ve anlamlı (p
Diagnóstico ultrassonográfico de abscesso prostático em canino SRD jovem orquiectomizado com paraparesia - relato de caso
Authors: De Oliveira Neto José Cardoso , Martins Junior Raul 
Published: December 2023

Abscessos prostáticos são descritos, rotineiramente, na clínica médica; porém, o diagnóstico, por vezes, pode tornar-se lento por existir a possibilidade de ser confundido com outras patologias. A principal causa dos abscessos prostáticos é a infecção do trato urinário inferior. As prostatopatias tendem a acometer com mais frequência animais idosos e não castrados. O presente trabalho relata um caso de um animal canino, de 5 anos de idade, com dificuldade de locomoção há mais de 1 ano. Referido animal deu entrada na clínica médica para realização de radiografia de coluna e internação para controle de dor. Após internação, foi identificado hematúria e o animal foi submetido a exames hematológicos, e, posteriormente, à ultrassonografia abdominal para auxiliar na identificação da causa base da hematúria. Na ocasião, restou visibilizada uma próstata aumentada e com a presença de galerias anecogênicas. Após a realização da ultrassonografia, foi realizada a punção da próstata e verificada a presença de conteúdo caseoso, tendo sido diagnosticado abscesso prostático.
Pessoas, estratégias e operações: os fundamentos da organização empresarial e da liderança de sucesso
Authors: Gomes Carla Prieto Contento , Ferreira Danieli Francine , Murasaki Denise Mitiko , De Andrade Laísa Ângelo , Vieira Leda de Aguiar , Utida Marina Atsuko , Moraes Rosângela Fátima Saris 
Published: December 2023

Esta é uma resenha do livro “Execução – a disciplina para atingir resultados”, de Larry Bossidy e Ram Charan, o qual trata de todo um conjunto de técnicas e de comportamentos para unir pessoas, estratégias e operações – os três processos essenciais a um negócio - a fim de garantir o sucesso ou, até mesmo, a sobrevivência de empresas. É fundamental a criação de uma cultura de execução dentro do universo empresarial, pois é ela a forma sistemática de se expor a realidade e de se agir sobre ela. Os autores ressaltam a importância de se ter as pessoas certas nos lugares certos, de se criar um modelo para uma mudança cultural dentro da empresa e de se ter uma liderança a qual insista no realismo, que estabeleça metas e prioridades claras e que amplie as habilidades das pessoas pela orientação. O livro destina-se a qualquer um que lidere pessoas no ambiente de trabalho.