bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE NUMBERED HEAD TOGETHER (NHT) TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMK
Authors: Mardiana Mardiana 
Published: October 2023

The instrument used in this research is a test of students' mathematical problem solving abilities which are tested. Before applied the model of learning in both classes pretest in both classes can be seen the result is the average value of control class is 37.6 and the average grade of experimental 38,83. Then after given the treatment of learning model in both classes then given the posttest and got the result is the average value of control class is 58,6 and experiment class average value is 62,77. After the final test, both classes were given a questionnaire of learning responses and obtained a percentage of student responses of 66.53% for the experimental class and 59% for the control class. Based on the results of this study can be concluded tha > or 0.716> 0.381 so it can be said that there is the influence of cooperative learning model type Numbered Head Together (NHT) to the problem solving skills mathematical students class XI SMK Pelita Hamparan Perak. While the results of the research for questionnaire responses obtained students < or -3.125 <1.675 so it can be concluded that there is no difference in student learning response taught by cooperative learning model type Numbered Head Together (NHT) with conventional learning model.
PENGEMBANGAN MEDIA DIORAMA TAMAN SATWA UNTUK MENINGKATKAN MINAT BELAJAR PESERTA DIDIK PADA MATA PELAJARAN IPA KELAS V MI
Authors: Nujum Tis'atun , Hamidah Allinda 
Published: October 2023

This study aims to develop taman satwa diorama media to increase students' learning interest, determine the feasibility level of taman satwa diorama media, and determine the level of students’ learning interest in science subjects class V MI Thoriqotul Hidayah Bulutigo after using taman satwa diorama media in learning activities. This type of research is research and development (R&D) used the ADDIE development model. The sample in this study were fifth grade students, totaling 10 students. The data collection technique in this study were questionnaires and documentation. The analysis technique used is descriptive qualitative and quantitative analysis. The results of research and development of taman satwa diorama media showed that taman satwa diorama media were appropriate to be used as learning media in fifth grade students in science subjects to increase students' learning interest. This could be seen from the results of the validation test of media experts by 91%, material experts by 82%, language experts by 88%, practitioners (teachers) by 100%, and from the results of field trials by 97.4% which showed very valid criteria. Based on the results of the data analysis of students' learning interest questionnaires, there was a significant difference in the initial and final students' learning interest with the acquisition of an average score which was initially only 55% with the moderate category increasing to 93% with the very high category. Thus it could be concluded that taman satwa diorama media can increase students' learning interest in science subjects of fifth grade students at MI Thoriqotul Hidayah Bulutigo for the 2022/2023 academic year.
Relação porto-cidade e a operacionalidade turística do terminal marítimo de passageiros de Natal – RN
Authors: Silva Júnior Francisco Xavier da , Nóbrega Wilker Ricardo de Mendonça 
Published: October 2023

O objetivo desta pesquisa centra-se em compreender quais são os obstáculos operacionais do turismo encontrados no Terminal Marítimo de Passageiros do Porto de Natal que culminam na relação porto-cidade. Para fundamentar o debate, explorou-se sobre os diversos teóricos que pensam zonas portuárias e suas conexões com a cidade e o turismo. Os dados foram obtidos através do material midiático e das atas institucionais do porto. Para analisá-los, foi utilizado como técnica o ciclo de análise issue-attention cycle de Downs (1972) para averiguar os traços das barreiras operacionais do terminal, verificando de que forma a mídia atuou em todo o processo, do pré-problema ao pós-problema. Após a aplicação do ciclo no contexto da política pública do TMP, foi possível entender que a frágil relação porto-cidade dificultou a interconexão com o turismo e não oportunizou um novo olhar para o bairro histórico. Todavia, acredita-se que os interesses na operacionalidade do TMP para fins turísticos são parte para justificar a necessidade de melhores empreendimentos turísticos e parte para estimular os grupos de interesse que se aproximam uns dos outros pelos acúmulos de seus capitais econômicos, culturais e sociais.
Assessing the effect of heavy metals on maize (Zea maysL.) growth and soil characteristics: plants-implications for phytoremediation
Authors: Atta Muhammad Imran , Zehra Syeda Sadaf , Ali Habib , Ali Basharat , Abbas Syed Naveed , Aimen Sara , Sarwar Sadia , Ahmad Ijaz , Hussain Mumtaz , Al-Ashkar Ibrahim , Elango Dinakaran , El Sabagh Ayman 
Published: October 2023

BackgroundHeavy metal pollution has become a global environmental issue. Heavy metals are contaminating the agro-soils, growing crops, and vegetables through different agricultural practices. In this study, besides the phytoremediation potential of maize, the role of chromium (Cr) and lead (Pb) on crop and soil health has been investigated.MethodsTwo maize varieties, Pak-Afgoi and Neelem, were grown under varying concentrations of Cr (50–300 ppm) and Pb (30–300 ppm) and different growth parametersi.e., seed germination, leaf size/number, stem girth, plant height, biomass, chlorophyll content, relative growth rate (RGR), and net assimilation rate (NAR) were studied under Cr and Pb stress. Likewise, the effect of metals was also assessed on different soil characteristics including soil texture, pH, EC, soil organic matter, urease activity and nutrients.ResultsStudied plant attributes were adversely affected by heavy metals toxicity. Affected values of RGR and NAR showed a linear correlation with affected growth and dry matter yield of maize. Heavy metals impacted different soil parameters including soil microbial performance and revealed a declining trend as compared to control soil. Maize varieties showed a significant phytoremediation potentiali.e., uptake of Cr and Pb was 33% and 22% in Pak-Afgoi, while Neelem showed 38% and 24% at 300 ppm, respectively. Data regarding metal translocation factor (TF), bioaccumulation factor (ACF), and biomagnification ratio (BMR) significantly revealed the potential of maize varieties in the removal of Cr and Pb metals from affected soils. However, Cr-accumulation was higher in shoots, and Pb accumulated in plant roots showed a differential behavior of metal translocation and affinity with the varieties. These maize varieties may be recommended for general cultivation in the Cr and Pb-contaminated areas.
Identification of genetic loci for early maturity in spring bread wheat using the association analysis and gene dissection
Authors: Kiseleva Antonina A. , Leonova Irina N. , Ageeva Elena V. , Likhenko Ivan E. , Salina Elena A. 
Published: October 2023

Background
Early maturity in spring bread wheat is highly desirable in the regions where it enables the plants to evade high temperatures and plant pathogens at the end of the growing season.

Methods
To reveal the genetic loci responsible for the maturity time association analysis was carried out based on phenotyping for an 11-year period and high-throughput SNP genotyping of a panel of the varieties contrasting for this trait. The expression of candidate genes was verified using qPCR. The association between the SNP markers and the trait was validated using the biparental F2:3 population.

Results
Our data showed that under long-day conditions, the period from seedling to maturity is mostly influenced by the time from heading to maturity, rather than the heading time. The QTLs associated with the trait were located on 2A, 3B, 4A, 5B, 7A and 7B chromosomes with the 7BL locus being the most significant and promising for its SNPs accelerated the maturity time by about 9 days. Gene dissection in this locus detected a number of candidates, the best being TraesCS7B02G391800 (bZIP9) and TraesCS7B02G412200 (photosystem II reaction center). The two genes are predominantly expressed in the flag leaf while flowering. The effect of the SNPs was verified in F2:3 population and confirmed the association of the 4A, 5B and 7BL loci with the maturity time.
The gray matter atrophy and related network changes occur in the higher cognitive region rather than the primary sensorimotor cortex after spinal cord injury
Authors: Chen Xin , Wang Ling , Zheng Weimin , Yang Yanhui , Yang Beining , Hu Yongsheng , Du Jubao , Li Xuejing , Lu Jie , Chen Nan 
Published: October 2023

Objective
This study used functional magnetic resonance imaging (fMRI) to explore brain structural and related network changes in patients with spinal cord injury (SCI).

Methods
Thirty-one right-handed SCI patients and 31 gender- and age-matched healthy controls (HC) were included. The gray matter volume (GMV) changes in SCI patients were observed using voxel-based morphometry (VBM). Then, these altered gray matter clusters were used as the regions of interest (ROIs) for whole-brain functional connectivity (FC) analysis to detect related functional changes. The potential association between GMV and FC values with the visual analog scale (VAS), the American Spinal Injury Association (ASIA) score, and the course of injuries was investigated through partial correlation analysis.

Results
GMV of the frontal, temporal, and insular cortices was lower in the SCI group than in the HC group. No GMV changes were found in the primary sensorimotor area in the SCI group. Besides, the altered FC regions were not in the primary sensorimotor area but in the cingulate gyrus, supplementary motor area, precuneus, frontal lobe, and insular. Additionally, some of these altered GMV and FC regions were correlated with ASIA motor scores, indicating that higher cognitive regions can affect motor function in SCI patients.

Conclusions
This study demonstrated that gray matter and related network reorganization in patients with SCI occurred in higher cognitive regions. Future rehabilitation strategies should focus more on cognitive functions.
Thermal Performance of Green Roofs in Dry Climate Regions of Mexico through Simulation with Energyplus and Openstudio Tools
Authors: Narváez Gerardo Ashrael Álvarez , Rangel Jaime Moisés Horta , Hernandez Miguel Ángel Pérez Lara y , Zaragoza Juan Bosco Hernández , Rea María Luz Pérez , García Enrique Rico , Lara Teresa López , Gonzalez Eduardo Rojas 
Published: October 2023

Place and Duration of Study: Faculty of Engineering, Universidad Autónoma de Querétaro, January 2022 to May 2023.
Green roofs are often used as an aesthetic resource by architecture, since they help to generate artificial green areas in densely populated urban areas, thanks to the fact that they occupy small spaces. This type of system has the quality that it also serves as a passive thermal insulation system. The majority of built green roofs are based on an extensive system, which is characterized by its low maintenance demand and low cost, as it has a shallow substrate and grass-based vegetation. However, in order to exploit the full potential of this system, the optimal parameters for each region must be studied, since the climatological characteristics of the place will directly affect its operation. Through the applied methodology, a base model configured in relation to a system previously established in the Autonomous University of Queretaro (UAQ) was obtained. With the model generated, the relationship between the thickness of the substrate and the decrease in internal temperature was studied, and differences of 5°C were obtained with respect to the external temperature.
Effects of Integrated Weed Management Practices on Weed Parameters and Yield of Bt Cotton (Gossypium hirsutum L.)
Authors: Reddy Vinod , Kulkarni Shyamrao , Chavan Mohan , Ajayakumar M. Y.  , Rudramurthy  
Published: October 2023

Aim: To know the effect of integrated weed management on weed parameters and yield of bt cotton.
Study Design: Randomized complete block design.
Place and Duration of Study: College of Agriculture Farm, Bheemaraynagudi between July 2021 and Feb 2022.
Methodology: The field experiment was conducted during Kharif 2021 at Experimental block, College of Agriculture, Bheemarayanagudi. The soil of the experiment field was deep black clayey in texture. The experiment comprises 11 weed management practices viz., T1: Pendimethalin 38.7% CS @ 750 g a.i./ha as PE + Hand weeding @ 20-25 DAS and Intercultivation @ 55-60 DAS, T2: Pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb Pyrithiobac Sodium 10 EC @ 75g a.i./ha + Quizalofop ethyl 5 EC @ 37.5g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS. (Tank mix), T3 : Pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb Pyrithiobac Sodium 10 EC @ 50g a.i./ha + Quizalofop ethyl 5 EC @ 25 g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T4 :Pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb Pyrithiobac Sodium 10 EC @ 75g a.i./ha + Quizalofop ethyl 5 EC @ 37.5g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T5 : Pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb Pyrithiobac Sodium 10 EC @ 100g a.i./ha + Quizalofop ethyl 5 EC @ 50g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T6 : Pyrithiobac Sodium 10 EC @ 50g a.i./ha + Quizalofop ethyl 5 EC @ 25g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T7: Pyrithiobac Sodium 10 EC @ 75g a.i./ha + Quizalofop ethyl 5 EC @ 37.5g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T8: Pyrithiobac Sodium 10 EC @ 100g a.i./ha + Quizalofop ethyl 5 EC @ 50g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS, T9: Farmers practice (Hand weeding @ 25 DAS and 2 intercultivations @ 50 and 75 DAS), T10: Weedy check, T11: Weed free check.
Results: Among the treatments, application of pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb pyrithiobac sodium 10 EC @ 100 g a.i./ha + quizalofop ethyl 5 EC @ 50 g a.i./ha as PoE (combi-product) @ 25 DAS and intercultivation @ 55-60 DAS recorded significantly lower weed density and higher weed control efficiency (82.39 %), also recorded higher seed cotton yield (2495 kg ha-1) and stalk yield (4056 kg ha-1) over other treatments.
Conclusion: Application of Pendimethalin 38.7 % CS @ 750 g a.i./ha as PE fb Pyrithiobac Sodium 10 EC @ 100g a.i./ha + Quizalofop ethyl 5 EC @ 50g a.i./ha as PoE @ 25 DAS and Intercultivation @ 55-60 DAS was found effective in controlling the weeds with coupled with higher seed cotton yield .
Genetic Variability and Correlation Studies for Yield and Yield Related Traits in Rice (Oryza sativa L.)
Authors: Madishetty Amulya Rani , Lal Gaibriyal M. , Adarsh K.  
Published: October 2023

The study aims to estimate the genetic parameters of 13 yield-attributing traits to study Genetic Variability and Correlation studies for yield and yield-related traits in rice. The investigation comprised of 20 Rice genotypes used for the experiment carried out during Kharif- 2022 in Randomized Block Design with three replications at the field Experimentation Center, Department of Genetics and Plant Breeding, Sam Higginbottom University of Agriculture Technology and Sciences, Prayagraj (Allahabad), India. The greater value of the phenotypic coefficient of variation (PCV) compared to the corresponding genotypic coefficient of variation (GCV) for all the studied traits indicated that there was an influence of the environment on biological yield per plant, Grain yield per plant, and test weight. All of the traits had high heritability, indicating that direct selection of these characters based on phenotypic expression using a simple selection procedure for yield improvement would be more accurate. Grain yield per plant showed a significant and positive association with biological yield, panicle length, no of spikelets per panicle, plant height, test weight, flag leaf width, and days to maturity indicating selection of these characteristics for yield improvement may be rewarding. Both at phenotype and genotype levels Biological yield per plant, panicle length, no of spikelets per panicle, plant height, test weight, days to flowering, days to maturity, and flag leaf width had positive direct effects on grain yield per plant indicating their importance during selection in the yield improvement program. Furthermore, the data gained by this study can be used in future rice breeding programs.
Effect of Inorganic Fertilizers and Biogas Slurry on Content and Uptake of NPK in Wheat Grown under Sodic Vertisols
Authors: Vishwakarma Megha , Bangre Jyoti , Khandkar U. R. , Tiwari S. C. , Vishwakarma Mahima 
Published: October 2023

Conjoint use of inorganic and organic amendments can be a pragmatic solution for improving soil physico-chemical and biological properties and sustaining crop productivity. Keeping in this view a pot experiment was conducted during rabi season of 2015-16 in net house of AICRP on Management of Salt Affected soils and use of Saline Water in Agriculture, College of Agriculture, Indore to study the effect of recommended doses of fertilizer and biogas slurry on uptake and content of NPK in wheat grown under sodic Vertisols. The treatment comprised of T0-Control, T1-100% RDF, T2- 100% RDF + 750 kg BGS ha-1, T3-75% RDF + 750 kg BGS ha-1, T4- 50% RDF + 750 kg BGS ha-1, T5- 100% RDF + 1000 kg BGS ha-1, T6-75% RDF + 1000 kg BGS ha-1, T7-50% RDF + 1000 kg BGS ha-1, T8-100% RDF + 1250 kg BGS ha-1, T9-75% RDF+ 1250 kg BGS ha-1, T10-50% RDF+ 1250 kg BGS ha-1 were laid in completely randomized design with 3 replications. Results showed that the treatment T9 (75% RDF+1250 kg BGS ha-1) gave maximum dry matter production (0.205, 0.434 and 0.821 g plant-1, respectively), N content (2.39, 1.58 and 1.36% respectively), P content (0.41, 0.30 and 0.24%, respectively) and K content (1.24, 0.68 and 1.68%, respectively) in wheat leaf at 30, 60 and 90 DAS. Maximum uptake of N (1.20 and 0.72 g pot-1, respectively), P (0.132 and 0.119 g pot-1, respectively) and K (0.237 and 1.08 g pot-1, respectively) by grain and straw of wheat respectively, were found with the application of T9 (75% RDF+1250 kg BGS ha-1). Thus, it may be concluded that integrated application of T9 (75% RDF+1250 kg BGS ha-1) not only increases dry matter production but also content and uptake by wheat.
From Bench to Bedside: A Scoping Review of Gene Therapy Approaches in the Management of Cardiomyopathies
Authors: Gopal Shwetha , Imtiaz Zainab , Ijishakin Olumide , Louise-Oluwasanmi Olusayo , Berhe Helen Surafeal , Emmanuel Ogunniyi Kayode , Oni Efe , Agbo Gift Joanna , Gabriel Kareeba Leefoon , Ezeamii Victor Chiedozie , Omole Janet , Okunzuwa Efe , Amiruddin Aaquib Syed , Okunromade Omolola , Rayapati Lakshmi Tulasi 
Published: October 2023

Background: Cardiomyopathies represent a heterogeneous group of heart muscle diseases with diverse etiologies. With the advent of molecular biology and genetic engineering, novel therapeutic strategies are being developed and explored to target the genetic basis of these diseases.
Methods: A scoping review was performed of studies published between 2017 and 2023, exploring gene-based therapeutic interventions for various forms of cardiomyopathies. Literature was selected from a wide range of international databases, including PubMed, EMBASE, and Web of Science, with selection criteria focused on the application of gene therapies in preclinical and clinical studies.
Findings: A total of 9 studies were included in the review, revealing various gene therapy strategies, including antisense therapies, gene editing, miRNA manipulation, and the use of gene therapy vectors for targeted treatment. Although most of the studies were conducted in preclinical models, they exhibited promising outcomes such as improved cardiac function, reduced fibrosis, and amelioration of disease phenotype. The review also highlighted the considerable heterogeneity among studies in terms of the disease models used, targeted genes, and measured outcomes, indicating the complexity of the field.
Conclusion: This scoping review presents an overview of the emerging gene therapy strategies for cardiomyopathies, revealing promising outcomes in preclinical models. However, several challenges remain, including the translation of findings from animal models to humans, ethical considerations, and potential disparities in access to these treatments. Future research should focus on addressing these challenges to pave the way for innovative, efficacious, and accessible therapies for patients with cardiomyopathies.
Amyloid Positron Emission Tomography and Subsequent Health Care Use Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia
Authors: Rabinovici Gil D. , Carrillo Maria C. , Apgar Charles , Gareen Ilana F. , Gutman Roee , Hanna Lucy , Hillner Bruce E. , March Andrew , Romanoff Justin , Siegel Barry A. , Smith Karen , Song Yunjie , Weber Christopher , Whitmer Rachel A. , Gatsonis Constantine 
Published: October 2023

ImportanceResults of amyloid positron emission tomography (PET) have been shown to change the management of patients with mild cognitive impairment (MCI) or dementia who meet Appropriate Use Criteria (AUC).ObjectiveTo determine if amyloid PET is associated with reduced hospitalizations and emergency department (ED) visits over 12 months in patients with MCI or dementia.Design, Setting, and ParticipantsThis nonrandomized controlled trial analyzed participants in the Imaging Dementia–Evidence for Amyloid Scanning (IDEAS) study, an open-label, multisite, longitudinal study that enrolled participants between February 2016 and December 2017 and followed up through December 2018. These participants were recruited at 595 clinical sites that provide specialty memory care across the US. Eligible participants were Medicare beneficiaries 65 years or older with a diagnosis of MCI or dementia within the past 24 months who met published AUC for amyloid PET. Each IDEAS study participant was matched to a control Medicare beneficiary who had not undergone amyloid PET. Data analysis was conducted on December 13, 2022.ExposureParticipants underwent amyloid PET at imaging centers.Main Outcomes and MeasuresThe primary end points were the proportions of patients with 12-month inpatient hospital admissions and ED visits. One of 4 secondary end points was the rate of hospitalizations and rate of ED visits in participants with positive vs negative amyloid PET results. Health care use was ascertained from Medicare claims data.ResultsThe 2 cohorts (IDEAS study participants and controls) each comprised 12 684 adults, including 6467 females (51.0%) with a median (IQR) age of 77 (73-81) years. Over 12 months, 24.0% of the IDEAS study participants were hospitalized, compared with 25.1% of the matched control cohort, for a relative reduction of −4.49% (97.5% CI, −9.09% to 0.34%). The 12-month ED visit rates were nearly identical between the 2 cohorts (44.8% in both IDEAS study and control cohorts) for a relative reduction of −0.12% (97.5% CI, −3.19% to 3.05%). Both outcomes fell short of the prespecified effect size of 10% or greater relative reduction. Overall, 1467 of 6848 participants (21.4%) with positive amyloid PET scans were hospitalized within 12 months compared with 1081 of 4209 participants (25.7%) with negative amyloid PET scans (adjusted odds ratio, 0.83; 95% CI, 0.78-0.89).Conclusions and RelevanceResults of this nonrandomized controlled trial showed that use of amyloid PET was not associated with a significant reduction in 12-month hospitalizations or ED visits. Rates of hospitalization were lower in patients with positive vs negative amyloid PET results.