bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ezrin promotes esophageal squamous cell carcinoma progression via the Hippo signaling pathway
Authors: Ma Lijuan , Liu Li , Ji Min , Su Liping , Guan Yaling , Xiao Jinling , Pu Hongwei 
Published: September 2023

Abstract
The aim of this study was to analyze the role of Ezrin in esophageal squamous cell carcinoma (ESCC) and investigate potential therapeutic targets for ESCC by interfering with Ezrin expression. Bioinformatics analysis revealed that Ezrin expression differed significantly among patients with different clinical stage ESCC. Moreover, there was a significant correlation between Ezrin and yes-associated protein/connective tissue growth factor (YAP1/CTGF) levels in esophageal cancer. Sixty paraffin-embedded ESCC tissue samples were examined and Ezrin and YAP1/CTGF levels were determined using immunohistochemistry. The positive expression rates of Ezrin and YAP1/CTGF were significantly lower in adjacent tissues than in ESCC tissues. Furthermore, knockdown of Ezrin expression inhibited colony formation and reduced cell migration and invasion. Compared with control ESCC cells, protein expression levels of YAP1 and CTGF were significantly downregulated in cells with Ezrin knocked down. We conclude that Ezrin may be involved in ESCC progression through the Hippo signaling pathway.
Akteure der Stadtplanung in der longue durée. Die Stadt Luxemburg
Authors: Pauly Michel 
Published: September 2023

Zusammenfassung
Der Beitrag geht der Frage nach, wer vom 10. bis ins 21. Jahrhundert für Stadtplanung und urbane Raumordnung verantwortlich war. Die institutionellen Akteure werden jeweils in den historischen Rahmenbedingungen politischer, sozialer, wirtschaftlicher und kultureller Natur betrachtet. Im Ergebnis werden Kontinuitäten in der Stadtentwicklung sichtbar, bei denen sich die Frage stellt, ob es sich um Pfadabhängigkeiten oder um die einzig mögliche Option handelte. Das heißt, es wird zu untersuchen sein, welche positiven Effekte die bisherige Entwicklung mit sich brachte, die erklären, warum alternative Pfade – wenn es denn solche gab – nicht eingeschlagen wurden. Vor allem der Festungscharakter der Stadt Luxemburg wird als Entwicklungspfad, dem schwer zu entrinnen ist, auf andere Städte übertragbar sein. Insofern lohnt sich der weite Blick in die Vergangenheit, auch weil viele Veröffentlichungen zur Planungsgeschichte sich auf die jüngsten Jahrzehnte beschränken. So lässt sich nachweisen, dass bis zum Londoner Vertrag von 1867, der die Schleifung der Festungsbauten verordnete, die Militärbehörden am nachhaltigsten wirkten. Seither herrscht eine Planungsrivalität zwischen Landes- und Stadtbehörden, während bis heute die Stadtbewohner kaum Mitspracherechte genießen. Ob die heute sehr verbreitete Verflechtung von politischer Stadt- und Landeselite und privaten Projektentwicklern ein Alleinstellungsmerkmal der Europastadt Luxemburg oder auch andernorts nachweisbar ist, werden erst Vergleichsstudien für andere Städte erweisen können.
Genese eines Feindbilds
Authors: Milz Kristina 
Published: September 2023

Abstract
Im frühen Stürmer ist der Nürnberger Max Süßheim (1876–1933) omnipräsent: Mitte der 1920er Jahre kam kaum eine Ausgabe des Hetzblatts ohne den Sozialdemokraten als Motiv aus, der als Anwalt zu den frühen Gegnern des Nationalsozialismus gehörte. Als Politiker hatte Süßheim zuvor eine wichtige Rolle in der Revolution von 1918/19 gespielt; bis heute ist er der letzte jüdische Landtagsabgeordnete Bayerns geblieben. Wie konnte eine solche Figur sogar in ihrer eigenen Partei in Vergessenheit geraten? Kristina Milz verortet den jüdischen Sozialdemokraten bürgerlicher Herkunft im vor- und frühdemokratischen Bayern und legt dabei die identitätszentrierte Argumentationslogik seiner Gegner offen, die Süßheim von links wie rechts stets auf seine Herkunft zurückwarf.
Zwischen Wehrmachtgemeinde und Gefängniszelle
Authors: Badstieber-Waldt Julika 
Published: September 2023

Abstract
Obwohl die Geschichte der Wehrmacht im Zweiten Weltkrieg intensiv erforscht worden ist, gibt es immer noch weiße Flecken, zu denen auch die Rolle der Wehrmachtseelsorger im deutsch besetzten Europa gehört. Julika Badstieber-Waldt nimmt sich dieses Themas am Beispiel des österreichischen Wehrmachtoberpfarrers Otto Gramann an, der zwischen 1940 und 1944 in Belgien/Nordfrankreich eingesetzt war. Ihr Aufsatz zeigt, wie sich die Rolle der Wehrmachtpfarrer mit zunehmender Dauer der Besatzung veränderte und immer mehr an Komplexität gewann. Während die Wehrmachtseelsorge ursprünglich ausschließlich für deutsche Soldaten gedacht war, waren in den westlichen Besatzungsgebieten rasch auch Häftlinge und zum Tode Verurteilte zu betreuen. Anhand von eindrucksvollen Quellen aus Gramanns Nachlass zeichnet Julika Badstieber-Waldt dessen Tätigkeit zwischen Militärgemeinde und Gefängniszelle nach, die in der Nachkriegszeit erstaunliche Beachtung fand.
INFÂNCIAS, FEMINISMOS E A EDUCAÇÃO
Authors: Ribeiro Moreira Cátia , Medianeira da Silva Flôres Vanessa 
Published: September 2023

O processo da Colonialidade deixou marcas na história que ainda ecoam com consequências drásticas até os dias atuais. Essas marcas afetaram adultos e aqui destacamos as mulheres negras, e não apenas estas, pois, as crianças e suas infâncias também foram afetadas. O racismo, o sexismo, o patriarcalismo e o adultocentrismo, são exemplos de categorias que tem influenciado de forma aniquiladora as mulheres e as crianças e suas infâncias. Esses fatores têm moldado as infâncias em uma sociedade excludente que colocam essas sujeitas em posições subalternas em relação as demais, principalmente as mulheres negras e crianças negras. Compreendemos que, essas práticas decorrentes sobretudo do período colonial, acentua cada vez mais um desequilíbrio econômico, social, político, cultural e social. Em diálogo com a teórica e escritora feminista bell hooks, sobretudo a partir de sua obra “ Ensinando a transgredir: a educação como prática da liberdade (2013)”, propomos pensar através dos conceitos chaves de “Sororidade” e “Pedagogia engajada”, como é possível uma educação que tenha em sua centralidade a luta antirracista, antissexista e que se posicione contraria ao adultocentrismo. Destacamos que as contribuições da feminista bell hooks, tem nos ajudado a pensar em uma educação feminista respeitosa, que tenha como foco o combate a qualquer tipo de opressão e que nos ajude a transformar e superar as desigualdades presentes na sociedade. Ressaltamos que nos estudos das infâncias e na Educação Infantil estas discussões são urgentes e necessárias em prol da superação de concepções cristalizadas sobre a educação que corroboram para reproduzir o sexismo e o racismo.
AS RELAÇÕES DE GÊNERO E HISTÓRIAS DE VIDAS DE MULHERES DO QUILOMBO DA COXILHA NEGRA/RS
Authors: Rinaldi da Rosa Graziela 
Published: September 2023

Conhecer quem são e como vivem as mulheres nos Quilombos de São Lourenço do Sul/RS foi um dos objetivos da pesquisa ação participante intitulada “Mulheres Quilombolas do Município de São Lourenço do Sul: Identidades, vivências e memórias dos quilombos”, desenvolvida com apoio da FAPERGS/CNPq, realizada entre os anos 2016-2019 nos cinco quilombos reconhecidos de São Lourenço do Sul. Nesse artigo, iremos apresentar um recorte dessa pesquisa, como ela foi desenvolvida no Quilombo da Coxilha Negra, de São Lourenço do Sul. Os encontros foram realizados com metodologias híbridas, como por exemplo: Entrevistas individuais e pré-estruturadas; encontros de grupo focal; Oficinas de Bonecas Negras, rodas de diálogos e observação da comunidade, juntamente com as mulheres que vivem nos quilombos. Com essa pesquisa foi possível realizar o primeiro estudo sobre a vida das mulheres dos Quilombos de São Lourenço do Sul, conhecendo suas demandas, suas histórias de vidas, os desafios cotidianos, seus sonhos e a própria história dos Quilombos a partir do protagonismo feminino, além de problematizar as relações de gênero, a divisão do trabalho, escolaridade, Violências, entre outros temas. Tais temas foram discutidos numa perspectiva feminista a partir de autoras que embasaram a pesquisa e as análises das histórias de vidas, como por exemplo: Bell Hooks (2019, 2021); Claudia Korol (2007); Marie-Christine Josso (2007) e Luz Maceira Ochoa (2008), Carla Akotirene (2019), Djamila Ribeiro (2019).
AGAMA SEBAGAI ALAT HEGEMONI DALAM KEKERASAN DOMESTIK PERSPEKTIF ANTONIO GRAMSCI
Authors: Hanafi Ifan 
Published: September 2023

Abstract. Domestic violence is difficult to resolve because this case in private area. Cases of domestic violence released by the Indonesian Ministry of Women Empowerment and Child Protection in 2021 reached 25,210 cases where women were victims. The percentage of these cases as much as 57.8% of violence occurred in the house which is domestic violence. From this number, it is assumed that there are still many unsolved cases. In some cases women feel willing and feel deserving of acceptance. To launch their actions, the husband as the dominant party often uses verses from the Qur'an to legitimize the violence committed. The wife as a subordinate party, psychologically has been locked to provide resistance. This is what Antonio Gramsci calls hegemony. The hegemony theory says that the leader who becomes dominant to pressure subordinates uses consensus or text so that his power will last because there is an agreement between the two parties. Through this theory, it will be able to map out the inaccurate interpretation of religion that is often used by husbands in carrying out domestic violence in the family. Use of QS. An-Nisa' verse 34 by the husband as the dominant party can subordinate the wife to do nuzyuz, namely by beating. With the understanding of this verse, the subordinate or the wife will eventually feel that the husband's actions are worthy of acceptance. Therefore, understanding of religion and understanding of gender needs to be instilled early or no later than before marriage. Abstrak. Kekerasan domestik sulit diselesaikan karena kasus ini mencakup wilayah yang privat. Kasus kekerasan domestik yang dirilis oleh Kemenppa RI pada tahun 2021 mencapai 25.210 kasus dimana perempuan sebagai korban. Persentase dari kasus tersebut sebanyak 57.8% kekerasan terjadi didalam rumah yang merupakan kekerasan domestik. Dari jumlah tersebut diasumsikan masih banyak kasus yang tidak terungkap. Dalam beberapa kasus perempuan merasa rela dan merasa pantas untuk menerima. Untuk melancarkan tindakannya, suami sebagai pihak dominan seringkali memakai ayat Al-Qur'an untuk legitimasi atas kekerasan yang dilakukan. Istri sebagai pihak subordinat, secara psikologis telah terkunci untuk memberikan perlawanan. Hal inilah yang oleh Antonio Gramsci disebut sebagai hegemoni. Teori hegemoni mengatakan bahwa pihak pemimpin yang menjadi dominan untuk menekan pihak subordinat menggunakan konsensus atau teks sehingga kekuasaannya akan langgeng karena terjadi persetujuan antara kedua belah pihak. Melalui teori ini akan mampu memetakan penafsiran agama yang kurang tepat yang seringkali digunakan oleh suami dalam melakukan kekerasan domestik dalam keluarga. Penggunaan QS. An-Nisa’ ayat 34 oleh suami sebagai pihak dominan dapat mengsubordinasi istri melakukan nuzyuz yakni dengan cara pemukulan. Dengan pemahaman ayat ini, pihak subordinat atau istri lama-lama akan merasa bahwa tindakan suami memang layak untuk diterima. Oleh karenanya pemahaman agama dan pemahaman gender perlu ditanamkan semenjak dini atau selambat-lambatnya sebelum menikah.
October 2023 ICD-10-CM Updates for Pediatrics
Authors:   American Academy of Pediatrics
Published: September 2023

Updates to International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) have been implemented for reporting with services provided on and after October 1, 2023. This update includes notable new and revised codes for reporting pediatric conditions, reasons for encounters, and social determinants of health that affect treatment or management. This article provides an overview of the following code changes that may be applicable in pediatric practice:
Appendicitis with and without perforation Nontraumatic coma Foreign bodies entering into or through natural orifices Foreign body sensation Medical clearance for placement outside parental care Newborn observation related to home physiologic monitoring Encounter for HIV preexposure prophylaxis Social determinants of health
ICD-10-CM Q Code Updates for Congenital Conditions
Authors:   American Academy of Pediatrics
Published: September 2023

Diagnosis codes in Chapter 17 of International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) describe congenital malformations, deformations, and chromosomal abnormalities other than inborn errors of metabolism. Multiple new Q codes have been added for services provided on and after October 1, 2023. This includes codes for the following:
Alagille syndrome Specified congenital malformation syndromes Types of craniosynostosis
Triangulations
Authors: Johnson Henry 
Published: September 2023

Japanese film director Nakae Y?ji’s 2009 feature film A Midsummer’s Okinawan Dream: Majir? of the Triangular Mountain (Manatsu no yo no Yume: Sankaku Yama no Majir?) is rooted in the culture, folklore and soundscapes of the Okinawan islands and uses imagery, sound, music and narrative to explore many traits that epitomize Okinawa’s distinct cultural identity in modern-day Japan. This article discusses the film from two main perspectives: (1) how different musical styles operate as distinct elements of the soundtrack (drawing on and embellishing their source contexts and traditions); and (2) how music functions in particular scenes and across the narrative in general. The article identifies the manner in which the film embraces local, national and global musical sources to provide a cultural soundscape that helps show some of the complexities of local identity construction in an era where regional identities are often contrasted against broader national and global influences.
Producción de forraje en híbridos de Urochloa bajo condiciones de sol y sombra de Melia azedarach L.
Authors: Jarillo-Rodríguez Jesús , Castillo-Gallegos Epigmenio , López-Ortiz Silvia 
Published: September 2023

Se evaluaron los híbridos de Urochloa CIAT BR02/1752 y CIAT BR02/1794, bajo condiciones de sol y sombra de árboles en una plantación de M. azedarach (1,000 árboles/ha). El estudio se desarrolló en Tlapacoyan (Veracruz, México), a 847 msnm, en un clima (A)C(m)w´(f), con temperatura media anual >18 °C, y precipitación de 1,991 mm/año. Las gramíneas se establecieron en marzo del 2019 usando material vegetativo, a una distancia de 0.5 × 0.5 m, en parcelas de 2.5 × 5 m, en un diseño de bloques completos al azar con tres repeticiones y un arreglo de parcelas divididas con la condición (sombra y pleno sol) en parcelas, los híbridos en subparcelas, las fechas de muestreo en sub-subparcelas y la edad de rebrote en sub-sub-subparcelas. Se midió la producción de materia seca (MS) por hijato y por macolla, así como también el rendimiento de MS total y de sus componentes, cortando a las 8 y 12 semanas de rebrote una muestra de un 1 m2 en el centro de cada sub-sub-subparcela. El material cosechado se separó en hojas y tallos y se secó a 55 °C durante 72 h. La MS/hijato fue afectada por la Edad (P<0.0001) y Grupo × Edad (P<0.0003); con el Grupo definido como la combinación de Condición × Híbrido. El rendimiento de MS/ha fue afectado (P<0.01) por la Condición, Edad, Condición × Edad y otras interacciones (con Híbridos, Fechas y Edades de muestreo). La MS/hijato fue más afectada por la condición de sombrío que por los híbridos. La producción de forraje fue mayor a pleno sol (1026.8±72.6 kg de MS/ha) que bajo sombra (505.3±72.5 kg de MS/ha), y lo mismo sucedió para hojas y tallos. El híbrido 1752 se comportó mejor que el 1794 (1026.9±72.7 and 695.3±72.7 kg DM/ ha, respectivamente). Así mismo, el rendimiento se incrementó con la edad de rebrote.
Characteristics of Buffalo Traders at the Bolu Animal Market, Toraja Regency, Indonesia
Authors: Sirajuddin Sitti Nurani , Rasyid Ilham , Baharudin  , Rosada Ida , Nurhapsa  
Published: September 2023

The Bolu animal market in North Toraja Regency is the largest livestock market in Indonesia and even in Southeast Asia.The purpose of this study was to determine the characteristics of buffalo livestock traders at the Bolu Animal Market, North Toraja Regency, Indonesia. This research was conducted at the Bolu Animal Market, Tallunglipu District, North Toraja Regency, South Sulawesi from December 2022 to January 2023. Research conducted by interview method. The research respondents were 43 buffalo livestock traders who sold on Bolu Animal market days. The results showed the characteristics of buffalo traders, namely the highest age at 39-46 years, the education of traders was highest at the junior high school level, the most trading experience was 9-12 years.
Modification of Carp (Osphronemus Gouramy) Growth with Insulin-Like Growth Factor-I Recombinant Mouse in Vivo
Authors: Restiadi Tjuk Imam , Satyantini Woro Hastuti , Triakoso Nusdianto 
Published: September 2023

Osphronemus gouramy consumption is increasing every year, which causes a high number of inquiries for this fish, which cannot be offset sufficiently by the amount of production. The growth rate of O. gouramy is relatively slow, so achieving the required consumption is relatively long. Quality improvement of productivity by improving the ability of cell metabolism to intake fish feed through hormone injection recombinant mouse insulin-like growth factor-I (IGF-I) is expected to spur growth so that fish production can be increased. This study aims to determine the effect of the hormone IGF-I recombinant mouse on the increased growth of O. gouramy. The benefits of this research are expected to deliver the benefits of science in the form of scientific information to the public in general and fish farmers, especially about the effect of the hormone recombinant mouse IGF-I on the growth of O. gouramy. The research method is carried out experimentally by using a completely randomized design (RAL); this study uses 80 O. gouramy was divided into 4 treatments P0: without hormone injections of IGF-I, P1: injected with the hormone IGF-I at a dose of 10 ng/ml, P2: injected with the hormone IGF-I at a dose of 20 ng/ml and P3: injected with the hormone at a dose of 40 ng/ml each of 5 replicates each test 4 tail O. gouramy. The hormone IGF-I recombinant mouse is done by injection. The treatment with hormone injection of recombinant mouse IGF-I. The parameters measured were growth. The results showed that the treatment hormone injection of recombinant mouse IGF-I with different doses gave significant differences (p <0.05); weight growth (P0: 0 ng/ml = 7,23 gram ± 0,37-gram dan P3: 40 ng/ml = 26,35 gram ± 1,89 gram.); length growth (P0 : 0 ng/ml = 5,76 cm ± 0,38 cm dan P3: 40 ng/ml = 7,93 cm ± 0,07 cm). The conclusion is that recombinant mouse IGF-I increased the growth by increasing in weight and length of O. gouramy, and improvement of the growth occurred in the treatment injection of the dose: 40 ng/ml.
Organic production - A strategic decision determining the agricultural income of small farms in Poland
Authors: Siemaszkiewicz Paweł 
Published: September 2023

Research objective: The main objective of the work was to determine the change in agricultural income after the implementation of organic production by small farms and to indicate the impact of organic production on the development of the farm, e.g. in the investment area.
Methodology: The study covered a group of 132 small farms engaged in organic production. The primary material was obtained using the survey method using a questionnaire. The study covered farms whose area did not exceed 10 hectares, where organic production was carried out and operated on the territory of the Republic of Poland.
Main conclusions: the implementation of organic production positively affects the agricultural income obtained by a small farm. It causes its growth and also favors making investments by the entity. Agricultural income is one of the basic factors motivating investment in farms. It guarantees a sense of economic security for the farmer and his family and affects the development of the farm.
Application of the study: The findings of this study can be instrumental for policymakers, agricultural organizations, and farmers in the Republic of Poland. By understanding the positive economic implications of organic production for small farms, stakeholders can make informed decisions about promoting and adopting organic farming practices. Additionally, financial institutions might consider these findings when offering financial products or incentives tailored for organic farmers.
Originality/Novelty of the study: This research stands out as one of the few comprehensive studies focusing on the economic implications of organic production specifically for small farms in the Republic of Poland. While there have been studies on organic farming, the emphasis on small farms, which often face distinct challenges and opportunities, brings a fresh perspective to the discourse.
Tarih Felsefesi Bağlamında Hegel ve Popper’ın Özgürlük Anlayışları Üzerine Karşılaştırmalı ve Eleştirel Bir Değerlendirme
Authors: İPLİKCİ Alper 
Published: September 2023

İnsan, tarihin içinde yaşayan bir varlık olduğu için onu tarihten bağımsız değerlendirme olanağı yoktur. Bu nedenle tarihi anlamlandırmak ve açıklayabilmek için önemli çabalar sarf edilmiştir. Tarih üzerine felsefe yapmak da böylesi bir çabayı ifade etmektedir. Felsefe tarihinin önemli filozoflarının insanı anlayıp açıklayabilmek amacıyla yapmış oldukları tüm rasyonel çalışmalarının temel bir ögesi de tarih felsefesidir. Tarih felsefesinin öncüleri denilebilecek isimler, tarihi felsefi bir biçimde irdeleyerek tarih üzerine çeşitli değerlendirmelerde bulunmuşlardır. Bu değerlendirmeler çerçevesinde birbirinden farklı birçok yaklaşım ileri sürülmüştür. Bunların içinde birbirini destekleyen yaklaşımlar olduğu gibi birbirinin tam karşıtı olan yaklaşımlar da söz konusudur. Fakat bu görüşlerin her birinin, insanlık tarihini anlayıp açıklayabilmek ve tarih üzerine yeni değerlendirmeler yapabilmek için temel niteliğinde olduğu tartışmasız bir gerçekliktir.
Felsefe tarihinin iki önemli filozofu G. W. F. Hegel ve K. R. Popper, tarihsel alanı felsefi bir biçimde ele alıp irdeleyen filozoflar arasında yer alırlar. Her iki filozofun tarih görüşleri de aynı zamanda bir özgürlük anlayışı ortaya koymaktadır. Popper, Hegel’in tarih görüşlerini eleştirerek onun özgürlük anlayışının karşıtı bir özgürlük anlayışı ileri sürmüştür. Çalışmamız, Hegel’in ve Popper’ın tarih görüşleri neticesinde ortaya çıkan özgürlük anlayışlarını karşılaştırmalı ve eleştirel bir biçimde değerlendirerek daha uygun bir özgürlük anlayışı ortaya koymayı amaçlamaktadır.