bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanistic Insight of Innovative Biomarkers for Screening of Type II Diabetes
Mellitus
Authors: Yadav Shubh Deep , Singh Neelam 
Published: December 2023

Abstract:
Diabetes Mellitus (DM) is a compounded, persistent illness symbolized by an increased range of glucose levels in the blood caused by cellular
resistance to insulin action, insufficient insulin production by pancreatic -cells, or both. Type 1 Diabetes Mellitus (T1DM), the extremely
widespread form of DM, is recorded for almost 85-90% of worldwide cases. T2DM is mostly common in middle-aged and older people, and its
causes are multifaceted. The use of efficient and profitable solutions for DM screening is critical to ensure pre-identification and minimising
patients' risk of acquiring the life-compromising illness. Identification of innovative biomarkers with test methods of DM is therefore critical in
order to establish vigorous, non-invasive, pain-free, highly sensitive, and precise procedures for screening. The purpose of this review article is to
mention and review all the necessary biomarkers that play a vital role in disease diagnosis and to highlight the present-day findings of the latest
clinically validated and traditional biomarkers and procedures for determining them, which provide cost-efficient options for T2DM screening with
early detection. It is concluded that various biomarkers, both conventional and innovative, go hand in hand to diagnose the DM of any type.
Peningkatan Pemecahan Masalah Matematika Menggunakan Model Pembelajaran Problem Based Learning Berbantuan Bar Modelling Untuk Siswa Sekolah Dasar
Authors: Jaya Greesla Anggera , Kelana Jajang Bayu 
Published: December 2023

Salah satu materi dalam pelajaran matematika di sekolah dasar yang sering menjadi masalah bagi siswa adalah Â pecahan. Â Siswa Â sering kesulitan Â dalam Â memahami Â pemecahan masalah terutama Â dalam menyelesaikan soal cerita yang berkaitan dengan pecahan. Tujuan penelitian ini adalah untuk mengkaji dan mengetahui ketercapaian peningkatan pemecahan masalah matematika menggunakan model pembelajaran problem based learningÂ berbantuan bar moddeling untuk siswaÂ sekolah dasar. Penelitian ini menggunakan metode kualitatif. Hasil pembelajaran matematika terhadap pemecahan masalah tentang konsep pecahan menggunakan bar modelling Â denganÂ beberapa Â tahapanÂ penelitian. Â Diantaranya adalah Â pemberian Â materi Â ajar Â sesuai skenario pembelajaran dengan menggunakan bar modelling, evaluasi akhir berupa tes tertulis yang diperoleh masing-masing siswa dibandingkan dengan kriteria ketuntasan minimal (KKM). Selain itu, hail penelitian menunjukkan bahwa siswa kelas VI SDK Yahya memiliki respon positif terhadap pembelajaran matematika dengan bar modelling.
Pengembangan Bahan Ajar Modul Berbasis Pendekatan Kontekstual Berbantuan Aplikasi Canva Materi Pecahan Untuk Meningkatkan Hasil Belajar Siswa Kelas III Sekolah Dasar
Authors: Rukman Vinka Riantini , Samsudin Asep 
Published: December 2023

Penelitian ini dilatar belakangi pada pelaksanaan kegiatan pembelajaran Matematika di Sekolah Dasar. Permasalahan yang dialami oleh guru yaitu kurangnya kemampuan dalam teknologi dan adanya keterbatasan kemampuan dalam penggunaan teknologi. Di sisi lain, terdapat permasalahan pada siswa yaitu kurangnya hasil belajar sehingga kualitas pendidikan individu menurun. Dengan begitu, memerlukan penggunaan bahan ajar tambahan yang menggunakan teknologi serta bisa dikembangkan atau di ciptakan oleh guru sebagai pilihan fasilitas dalam membimbing siswa di kelas terhadap materi pecahan. Pada penelitian memakai metode Research and Development (R&D) serta mengumpulkan berbagai data meliputi lembar validasi ahli, respon penggunaan dari siswa. Berdasarkan penelitian yang sudah dilakukan memperlihatkan hasil jikaÂ pengembangan Modul menggunakan model Borg and Gall. Penilaian dilaksanakan oleh validator yakni ahli media dan ahli materi menyatakan pengembangan bahan ajar termasuk kedalam kategori â€œSangat Layakâ€ agar bisa diimplementasikan kepada siswa. Respon dari para pengguna menyatakan pengembangan bahan ajar yang sudah dilakukan termasuk kedalam kategori â€œSangat Baikâ€ jika dipergunakan pada kegiatan belajar Matematika.
Racismo ambiental e o caso Braskem em Maceió-AL
Authors: Silveira Alexandre Marques , França Karine Agatha , Dias Felipe da Veiga 
Published: December 2023

A Braskem é uma das empresas petroquímicas mais rentáveis do Brasil e, desde a década de 1970, minerou sal-gema na cidade de Maceió, em Alagoas. Em 2018, a prática da empresa provocou o afundamento do solo em cinco bairros da cidade, atingindo cerca de 14 mil domicílios. A presente pesquisa busca saber qual é a relação existente entre as práticas de racismo ambiental e o caso Braskem em Maceió-AL? Para tanto, as bases teóricas que fundamentam a investigação partem da literatura em criminologia verde do Sul, sobretudo, trazendo uma perspectiva da teoria do dano social e das bases epistemológicas do racismo ambiental. Utilizou-se o método dedutivo e monográfico, bem como a técnica de pesquisa da documentação indireta. A conclusão indica que o caso da Braskem em Maceió, no estado de Alagoas, insere-se na lógica do racismo ambiental praticado por Estados, mercados e corporações, em conexão com o projeto político e econômico de exclusão e eliminação das populações pobres e marginalizadas. Isso ocorre porque Alagoas ocupa a terceira posição no ranking dos estados com extrema pobreza no Brasil, conforme dados do IBGE, e vem sofrendo há anos com os danos socioambientais perpetrados pela empresa.
Palavras-chave: Criminologia Verde; Crimes dos poderosos; Danos sociais; Racismo ambiental.
Educational Innovation for Industry 4.0: An Exploration of Integrated Work-Based Learning's Contribution
Authors: Prohimi Afwan Hariri Agus , Syihabudhin  , Juariyah Lohana , Bidin Rosmiza , Gunawan Ari , Syafruddin Afis Baghiz 
Published: December 2023

Purpose: The purpose of this research is to explore the role of integrated work-based learning in preparing students to meet the challenges of the Industry 4.0 work environment. It aims to investigate how incorporating work-based learning elements into the educational curriculum can enhance students' readiness for the dynamic and technology-driven landscape of Industry 4.0.

Theoretical framework: This study is grounded in the theoretical framework of constructivism and experiential learning. Constructivism emphasizes active learning and the development of meaningful understanding through real-world experiences. Experiential learning theories, particularly Kolb's model, inform the research, highlighting the importance of concrete experiences, reflective observation, abstract conceptualization, and active experimentation in the learning process.

Method/design/approach: A mixed-methods approach will be employed for this research. Quantitative data will be collected through surveys and assessments to measure the impact of integrated work-based learning on students' technical and soft skills. Qualitative data will be gathered through interviews and focus groups to explore students' perceptions and experiences.

Results and conclusion: The results will provide insights into the effectiveness of integrated work-based learning in enhancing students' technical and soft skills. It will reveal the impact on their readiness for Industry 4.0 careers, as well as their ability to navigate the complexities of the modern workplace.

Research implications: This research holds implications for educational institutions, policymakers, and industry stakeholders. It underscores the need to integrate work-based learning elements into curricula to better prepare students for Industry 4.0 careers. The findings will inform the development of strategies that enhance students' workforce readiness.

Originality/value: This research contributes to the growing body of literature on work-based learning and its role in Industry 4.0 preparedness. It provides original insights into the effectiveness of integrated work-based learning programs, their impact on students, and their value in addressing the demands of the rapidly evolving work environment.
Urban Agglomeration: A Qualitative Assessment of Landscape Patterns on a Slope in Jaboatão dos Guararapes, Pernambuco
Authors: Albuquerque Rejane de Assis , Lafayette Kalinny Patricia Vaz , Da Silva Rayane Gabriella Pereira , Ferreira Vinícius Dias , Pessoa Neto Amaury Gouveia , Da Silva Luciana Cássia Lima 
Published: December 2023

Objective: To carry out a qualitative assessment on a slope in Jaboatão dos Guararapes/PE, due to its physical-natural characteristics and significant inadequate urbanization.

Theoretical Framework: Urban growth, associated with disordered occupation, causes a series of changes in the environment. This urbanization without adequate planning can have several negative consequences for the environment and the population's quality of life.

Method: The Impact Matrix was used to facilitate the visualization and assessment of impacts on the different components of the environment, enabling a qualitative analysis. An assessment of possible impacts was also carried out, based on criteria, regarding environmental factors in the physical, biotic and anthropic environment, as well as actions that can be eliminated or mitigated.

Results and conclusions: With the application of the methodology, it was possible to make decisions to establish planning, support environmental management and resolve land use and occupation conflicts in terms of socio-environmental impacts. As for positive impacts, environmental education raised awareness among the population. In relation to negative impacts, greater attention from the population in the hillside area and on the river bank is important, especially in the winter period, when intense rains are observed, which can alter soil parameters, increasing landslides and floods.

Implications of the research: Methodologies used to eliminate or minimize impacts caused by the urban growth process.

Originality/value: This study proposed to evaluate the impacts of human actions in the city of Jaboatão dos Guararapes.
Analisis Fatwa MUI Nomor 4 Tahun 2003
Authors: Desriani Desriani , Hasibuan Zulfan Efendi , Harahap Risalan Basri 
Published: December 2023

Various kinds of culinary are rife in the middle of the city of padangsidimpuan by using thr name of processed food using a strange name. one of the branded products thet are currently becoming a tren in the community are meatballs with children, devil’s noodles, missile meatball cones and so on.Islam requires that the products to be consumed will be guaranteed to be halal and pure. Halal is not only from the type but also from the name. where in the explanation of the MUI Fatwa Number 4 of 2003 concerning standardization of halal fatwas, it is contained in the fourth section: the problem of using names and ingredients in point 1, namely “not to consume and use names and/or symbols of food/drinks that leat to kufr and falsehood”. From this background for naming processed foods in padangsidimpuan city based on MUI Fatwa Analysis Number 4 of 2003.This research is a field research. The research used is to collect data on the phenomena that occur. The data sources of this research are primary data and secondary data. Data collection techniques using field studies, namely ovservation, interviews and documentation.The results of this study indicate that traders or sesllers give the names of the foods they make with strange names because of the many business competitors. Based on the MUI Fatwa Number 4 of 2003, the author’s analysis of the naming of processed foods that are contrary to the MUI Fatwa are devil noodles, dragon whiskers, and devil’s chili chicken, while the names of processed foods that are allowed or not contrary to the MUI Fatwa Number 4 of 2003 such as meadballs with planet chicken because these names do not lead to kufr/falsehood as described in the MUI Fatwa.
Double pituitary neuroendocrine tumors in a patient with normal growth hormone level acromegaly: A case report and review of the literature
Authors: Nakazato Ichiro , Oyama Kenichi , Ishikawa Hisashi , Tabei Yusuke , Inomoto Chie , Osamura Yoshiyuki , Teramoto Akira , Matsuno Akira 
Published: December 2023

Background:
Acromegaly is a rare disease caused by growth hormone (GH) hypersecretion caused by a pituitary neuroendocrine tumor (PitNET). However, some acromegaly patients show normal GH levels, and they can be a pitfall in clinical diagnosis. Moreover, rarely, synchronous true double or multiple PitNETs are encountered. Moreover, these PitNETs increase the risk of a left lesion during surgical exploration.

Case Description:
The patient, who was a 73-year-old female, was referred to our hospital with a chief complaint of headache. Assessment of basal anterior pituitary function revealed a slightly high level of insulin-like growth factor-1 (IGF-1) (standard deviation, 2.4), and her physical findings exhibited mild acromegalic features. The endocrine evaluation confirmed acromegaly and magnetic resonance imaging (MRI) showed a macro PitNET with suprasellar extension. Endoscopic endonasal surgery (EES) was performed to remove the macro PitNET. Although postoperative MRI showed complete removal of the macro PitNET, endocrinological testing indicated no improvement in GH or IGF-1 excess. Pathological examination of the surgical specimen revealed a gonadotropic PitNET. Therefore, we repeated the MRI scan and found a micro PitNET in the thin left normal pituitary gland. A second EES was successfully performed to remove the micro PitNET completely, and both endocrinological and pathological examinations confirmed that the disease was cured.

Conclusion:
Diagnosing acromegaly with low GH levels requires close monitoring. Double PitNETs are relatively rare and can cause incomplete remission of functional PitNETs.
Prevalence of idiopathic normal pressure hydrocephalus in patients with vertebral compression fractures
Authors: Tanaka Tatsuya , Iwashita Hideki , Liu Xuan , Momozaki Nobuaki , Honda Eiichiro , Matsuno Akira , Morimoto Tadatsugu 
Published: December 2023

Background:
Patients with idiopathic normal pressure hydrocephalus (iNPH) may be more prone to all fracture types due to falls. Vertebral compression fractures (VCFs) are a global burden that temporarily or permanently affects millions of elderly people. This study aimed to investigate the prevalence of iNPH in patients with VCFs.

Methods:
We retrospectively reviewed 128 patients aged 60–102 years who underwent balloon kyphoplasty (BKP) for VCFs between November 1, 2017, and March 31, 2020. We also assessed the presence of the iNPH triad (i.e., gait disturbance, cognitive impairment, and urinary incontinence). Patients with Evans’ index (EI) >0.3 and the iNPH triad were defined as having possible iNPH, those with clinical improvement after a cerebrospinal fluid tap test were defined as having probable iNPH, and those with clinical improvement after a shunt surgery were defined as having definite iNPH.

Results:
Of the 128 patients, seven were excluded due to a history of intracranial disease that could cause ventricular enlargement or gait disturbance. Another 70 patients who did not undergo head computed tomography or magnetic resonance imaging one year before or after BKP were excluded from the study. Finally, 51 patients with a mean age of 78.9 years were enrolled. The mean EI value of these 51 patients was 0.28, with 18 patients showing EI >0.3. Moreover, 18 had possible iNPH, one had probable iNPH, and one had definite iNPH.

Conclusion:
Screening for iNPH in elderly patients with VCFs can allow early diagnosis of iNPH and benefit them more from surgical treatment.
DIREITO, ARTE E ANTROPOFAGIA
Authors: De Oliveira Mara Regina 
Published: December 2023

Este artigo retoma a ideia modernista de antropofagia, pensada por Oswald de Andrade, como uma metáfora criativa para expressar o ato de deglutição canibal como meio de transformação da estética europeia, para recriá-la com olhos de brasilidade. Uma das ideias propostas no manifesto refere-se, explicitamente, ao direito, quando diz: Perguntei a um homem o que era o Direito. Ele me respondeu que era a garantia do exercício da possibilidade. Esse homem chamava-se Galli Mathias. Comi-o. Esta genial frase de Oswald de Andrade, que usa um nome autoral fictício de Galli Mathias, aparece como epígrafe de um instigante livro chamado Teoria da Norma Jurídica, de autoria Tercio Sampaio Ferraz Jr. Em nossa análise, demonstraremos como esta obra desenvolve um inteligente e original estudo pragmático-linguístico da norma jurídica, que parte, a nosso ver, de uma deglutição de autores estrangeiros geradora de uma reflexão autoral interdisciplinar muito relevante. As reflexões pragmáticas também ganham ressonância em outras obras que destacam a análise histórica e artística de obras de William Shakespeare, reforçando o elemento antropofágico de sua caracterização metodológica interdisciplinar.
Laju Pengendapan dan Konsentrasi Hidrokarbon di Sedimen Perairan Sungai Donan
Authors: Handayani Yanny 
Published: December 2023

Tujuan penelitian ini adalah menghitung sebaran hidrokarbon di permukaan perairan, ketebalan hidrokarbon di permukaan perairan dan laju pengendapan konsentrasi hidrokarbon di sedimen dengan pendekatan model hidrodinamika menggunakan Persamaan Stokes. Metode pelaksanaan dilakukan sampling in situ maupun ex situ pada tujuh stasiun sejak Mei sampai Juni 2010. Laju pengendapan hidrokarbon kecepatan 0,0054 m/detik, proses pengendapannya berkisar 15,43 menit dengan ketebalan rerata lapisan minyak 0,047 mikrometer, volume minyak yang tumpah di perairan sekitar 102 mililiter dengan jarak distribusi sebaran minyak di permukaan air 281,63 meter.
Pembuatan Adsorben Co2 Berbahan Dasar Zeolit Alam Yang Diimpregnasi Dengan Methyl Diethanol Amine Dan Uji Kapasitas Adsorpsi Co2 Dengan Sistem Batch
Authors: Adriany Roza Adriany , Sakarani Devitra , Haris Abdul , Yenti Efa , Herlina Leni , Hidayati Nurul , Morina Morina , Herizal Herizal , Atmoko Atyanto Daru , Suhartono Rudi , Arief Rahmadian 
Published: December 2023

Telah dilakukan penelitian mengenai pembuatan adsorben CO2 berbahan dasar zeolit alam dari daerah Bayah dan pengujian kapasitas adsorpsi CO2 dengan sistem batch. Metodologi pembuatan adsorben adalah zeolit diaktivasi kemudian diimpregnasi dengan MDEA yang mengandung Piperazin 6% yang berfungsi sebagai aktivator reaksi. Konsentrasi MDEA yang diimpregnasikan yaitu 10% dan 15%. Adsorben kemudian dianalis dengan alat FTIR, XRD, SEM, dan dilakukan uji kapasitas adsorpsi CO2 pada suhu ruang menggunakan alat uji adsorpsi CO2 sistem batch. Hasil penelitian menunjukkan kapasitas adsorpsi CO2 maksimum diperoleh pada konsentrasi MDEA 15% yaitu 5,152 mg CO2 /g adsorben.
PEMBERDAYAAN KELOMPOK PKK MELALUI PELATIHAN BUDIDAYA MICROGREENS SEBAGAI UPAYA PEMANFAATAN LAHAN SEMPIT DI KELURAHAN BLIMBING
Authors: Putri Adhellya Novia , Puspitasari Elfi Indriani , Rahman Eric Andika , Vilantika Elok 
Published: December 2023

Kegiatan sosialisasi dan pelatihan budidaya microgreens telah menjadi inisiatif yang penting dan bermanfaat bagi Ibu-Ibu PKK di Kelurahan Blimbing. Wilayah yang padat penduduk sering kali memiliki kendala dalam memanfaatkan lahan sempit untuk keperluan pertanian. Dalam rangka mengatasi masalah ini, program kerja pelatihan ini didesain untuk memberikan pengenalan dan pemahaman dalam menanam dan merawat microgreens. Kegiatan sosialisasi melibatkan interaksi komunitas dan penyuluhan tentang manfaat budidaya microgreens sebagai solusi cerdas dalam memaksimalkan lahan sempit. Selanjutnya, pelatihan prakti s memberikan panduan langkah demi langkah tentang teknik penanaman, perawatan, dan pemanenan microgreens. Selama pelatihan, para peserta juga diajak untuk berpartisipasi aktif, mempraktikkan konsep yang diajarkan. Hasil evaluasi awal menunjukkan bahwa kegiatan ini telah memberikan manfaat yang signifikan bagi Ibu-Ibu PKK di Kelurahan Blimbing. Mereka telah meningkatkan pemahaman mereka tentang potensi lahan sempit dalam budidaya microgreens. Selain itu, pelatihan ini juga mendorong kolaborasi komunitas dala m menciptakan lahan pertanian bersama, meningkatkan asupan gizi keluarga, serta memberikan peluang tambahan melalui penjualan hasil panen microgreens. Kegiatan sosialisasi dan pelatihan budidaya microgreens ini memiliki potensi untuk meningkatkan ketahanan pangan, kemandirian ekonomi, dan kesejahteraan keluarga di Kelurahan Blimbing. Program ini juga menciptakan lingkungan yang mendukung pertanian perkotaan berkelanjutan dan berkontribusi pada pengelolaan lahan yang lebih efisien dalam wilayah yang padat penduduk.
Картины Поля Сезанна в Собрании И. А. Морозова
Authors: Семенова Наталия 
Published: December 2023

Аннотация
В статье прослеживается история прославленной коллекции картин Поля Сезанна Ивана Морозова с момента приобретения первых работ в 1907 году (La Montagne Sainte-Victoire vue du chemin de Valcros, c.1878–1879, Государственный музей изобразительных искусств имени А. С. Пушкина, Москва; и Nature morte à la draperie, c.1892–1894, Государственный Эрмитаж, Санкт-Петербург) до национализации коллекции в 1918 г.; его преобразование в 1919 г. во Второй музей новой западной живописи, переименованный в 1923 г. во Второй музей нового западного искусства; слияние в 1928 г. с коллекцией Сергея Щукина и образование Государственного музея нового западного искусства, располагавшегося в бывшем особняке Морозова; продажа некоторых работ Сезанна в 1930-х годах; окончательное закрытие музея в 1948 году, когда произведения были распределены между ГМИИ им. А. С. Пушкина и Государственным Эрмитажем. Отчет включает, где это возможно, происхождение и даты покупки конкретных произведений, суммы, которые заплатил Морозов, а также отношения коллекционера с различными дилерами, такими как Амбруаз Воллар и Поль Дюран-Рюэль. К сожалению, фотографий того, как развешивалась коллекция до революции, нет, поэтому автор изучает различные рассказы и впечатления посетителей, которые дают некоторое представление о том, как она могла выглядеть. Поскольку Морозов был менее склонен показывать свою коллекцию художникам и отдельным представителям публики, чем Щукин, эти сведения ограничены. Первые фотографии развески датируются началом 1920-х и сделаны после национализации в 1918 году.
Сезанн и сезаннизм в исследовательской практике Государственного института художественной культуры
Authors: Карасик Ирина 
Published: December 2023

Аннотация
Данная статья посвящена той роли, которую теория и практика Сезанна сыграли в исследовательской работе, проводившейся под руководством Казимира Малевича в Государственном институте художественной культуры (Гинхуке) в Петрограде/Ленинграде в 1924–1926 гг. Это свидетельствовало о появлении более аналитического и теоретического отношения к Сезанну. Придя к пониманию супрематизма как кульминации живописи, Малевич теперь сосредоточился на изучении вопросов, связанных с “живописной культурой” и “наукой об искусстве,” формулируя свою теорию добавочного элемента в живописи. Сезанн был ключевой фигурой в генезисе и разработке этих идей, а также в разработке Малевичем понятия “живопись как таковая” и понятия “живописная ткань.” Эти теории легли в основу новой учебной программы Малевича для художников. Автор рассматривает теории Малевича в том виде, в каком они развивались в Гинхуке, и институтские исследования поверхности живописи, света, цвета, структуры, объема, композиции и фактуры. Она также исследует подход Константина Рождественского к Сезанну, воплощенный в его неопубликованном эссе “Живописная система Сезанна”.