bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nomogram for preoperative estimation of symptomatic subdural hygroma risk in pediatric intracranial arachnoid cysts
Authors: Zhao Heng , Chen Yufan , Tian Shuaiwei , Wang Baocheng , Zhao Yang , Ma Jie 
Published: December 2023

OBJECTIVE
The occurrence and predictors of symptomatic subdural hygroma (SSH) subsequent to the fenestration of pediatric intracranial arachnoid cysts (IACs) are unclear. In this study, the authors aimed to investigate the likelihood of an SSH following IAC fenestration and the impact on operative efficacy with the ultimate goal of constructing a nomogram.

METHODS
The medical records of 1782 consecutive patients who underwent surgical treatment at the Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine were reviewed. Among these patients, a training cohort (n = 1214) underwent surgery during an earlier period and was used for the development of a nomogram. The remaining patients formed the validation cohort (n = 568) and were used to confirm the performance of the developed model. The development of the nomogram involved the use of potential predictors, while internal validation was conducted using a bootstrap-resampling approach.

RESULTS
SSH was detected in 13.2% (160 of 1214) of patients in the training cohort and in 11.1% (63 of 568) of patients in the validation cohort. Through multivariate analysis, several factors including Galassi type, IAC distance to the basal cisterns, temporal bulge, midline shift, IAC shape in the coronal view, area of the stoma, and artery location near the stoma were identified as independent predictors of SSH. These 7 predictors were used to construct a nomogram, which exhibited a concordance statistic (C-statistic) of 0.826 and demonstrated good calibration. Following internal validation, the nomogram maintained good calibration and discrimination with a C-statistic of 0.799 (95% CI 0.665–0.841). Patients who had nomogram scores < 30 or ≥ 30 were considered to be at low and high risk of SSH occurrence, respectively.

CONCLUSIONS
The predictive model and derived nomogram achieved satisfactory preoperative prediction of SSH. Using this nomogram, the risk for an individual patient can be estimated, and the appropriate surgery can be performed in high-risk patients.
Safety and efficacy of intrathecal baclofen trials for the treatment of hypertonia: a retrospective cohort study
Authors: Abdelmageed Sunny , Horak Victoria Jane , Mossner James , Wang Ryan , Krater Timothy , Raskin Jeffrey S. 
Published: December 2023

OBJECTIVE
Intrathecal baclofen (ITB) is an effective treatment for refractory hypertonia in children. ITB has long been effective for the treatment of spasticity, and indications have naturally evolved to include dystonia and mixed pediatric movement disorders (PMDs). The established uses for ITB trials are insurance prerequisite, mixed tone, and family request. Despite agreement for ITB therapy by a multidisciplinary group of subspecialists in a complex PMD program, insurance companies often require an ITB trial be performed. A longitudinal cohort was identified to determine the safety and efficacy of ITB trials and to determine the utility of test dosing in this population.

METHODS
Retrospective data analysis was performed for patients with hypertonia who underwent ITB bolus trials at the authors’ institution between 2021 and 2023. Nonmodifiable risk factors and clinical variables were collected.

RESULTS
Thirty-one patients (11 female) underwent 32 ITB trials. Of these patients, 67.7% had a diagnosis of mixed hypertonia, 32.3% pure spasticity, and 9.1% secondary dystonia. The mean age at test dose was 12.8 years, and 58.1% of patients were born premature. The mode Gross Motor Function Classification System score was 5. The mean difference in Barry-Albright Dystonia Scale (BADS) scores was −7.33 points (p = 0.01) at 2.5 hours postoperatively. The mean difference in upper-extremity modified Ashworth Scale (mAS) scores was −5.36 points (p = 0.003), and that for lower-extremity mAS scores was −6.61 (p < 0.001). In total, 21.9% of patients developed a post–dural puncture headache. Conversion to a permanent baclofen pump was performed in 22/32 (68.8%) patients. Of those who did not pursue pump placement, 1 patient had high surgical risk, 1 had an ineffective response, 1 had a bad reaction to the test dose and cited both regression and increased discomfort, and 2 declined despite an effective trial owing to family preferences.

CONCLUSIONS
ITB trials require hospitalization in some form and carry risks of procedural complications. The decision to pursue a trial should be made on a case-by-case basis by clinicians and should not be determined by insurance companies. The complication rate of ITB trials is high, and a test dose is unnecessary in this fragile population.
PERBANDINGAN KADAR ALANINE AMINOTRANSFERASE BERDASARKAN FREKUENSI TRANSFUSI DARAH PASIEN TALASEMIA β MAYOR DI RSD BANJARBARU
Authors: Rahmawati  , Oktiyani Neni , Kustiningsih Yayuk , Cahyono Jujuk Anton 
Published: December 2023

Talasemia merupakan kelainan darah bawaan yang diakibatkan adanya gangguan sintesis hemoglobin di dalam sel darah merah yang mengharuskan mereka untuk mendapatkan transfusi secara rutin. Transfusi yang berulang-ulang dapat menyebabkan penumpukan zat besi dalam tubuh terutama organ hati, sehingga menyebabkan kadar Alanine Aminotransferase meningkat. Penelitian bertujuan mengetahui perbandingan kadar ALT berdasarkan frekuensi transfusi darah pada penderita talasemia β mayor di RSD Banjarbaru. Penelitian ini menggunakan jenis penelitian survei analitik. Teknik pengambilan menggunakan teknik accidental sampling. Hasil penelitian sebanyak 9 orang (30%) subjek penelitian memiliki kadar ALT diatas normal. Hasil pemeriksaan kadar ALT transfusi darah 2 minggu sekali kisaran 15-70 U/L, 3 minggu sekali kisaran 30-51 U/L, dan 4 minggu sekali kisaran 12-41 U/L. berdasarkan Uji One Way Anova didapatkan signifikansi (p = 0,044) yang berarti terdapat perbedaan bermakna paling tidak antar 2 kelompok. Kesimpulan ada perbedaan yang bermakna antara kadar ALT dengan frekuensi transfusi darah.
Faktor Risiko Infeksi Sifilis Pada Warga Binaan Pemasyarakatan Di Wilayah Kerja Puskesmas Cempaka Banjarbaru
Authors: Hafidh Muhammad , Nia Alda , Adawiyah Rabiyatul , Khatami Azizah Mustika , Herlina Tini Elyn 
Published: December 2023

Abstrak
Infeksi menular seksual (IMS) masih menjadi masalah besar sampai saat ini. Menurut survei terpadu biologi dan perilaku (STBP) tahun 2011, prevalensi sifilis pada warga binaan pemasyarakatan (WBP) yaitu 5%, populasi sifilis pada positif HIV sebesar 23,8% sedangkan pada HIV negatif 16,67%.Warga binaan merupakan salah satu populasi yang berisiko terinfeksi sifilis, pada lingkungan padat hunian prevalensi penyakit menular cenderung lebih tinggi dibandingkan di luar penjara.Tujuan dari penelitian adalah untuk mengetahui faktor risiko infeksi sifilis pada warga binaan pemasyarakatan di wilayah kerja Puskesmas Cempaka Banjarbaru. Penelitian ini menggunakan teknik purposive sampling dengan jumlah populasi WBP pada lapas kelas II B Banjarbaru blok kamar 1 B sampai 10 B sebanyak 100 orang dan 40 orang yang memenuhi kriteria inklusi dan eksklusi. Sampel diuji skirining dengan metode VDRL dan uji semi kuantitatif metode TPHA, untuk melihat bahwa sampel benar-benar positif sifilis bukan positif infeksi lain/positif palsu. Dari hasil pemeriksaan ada 3 orang responden dengan hasil TPHA positif dan VDRL negatif, serta satu orang responden positif sifilis. Setelah dianalisis data menggunakan uji Chi-Square Fisher dapat disimpulkan tidak ada hubungan faktor risiko yang diteliti terhadap kejadian sifilis dengan Odds Rasio lama tahanan (0,484), hubungan seksual (0,867), transfusi darah (0,846), memiliki tato (0,417), narkoba suntik (0,897), dan variabel pengetahuan (1,174) berisiko terkena sifilis pada warga binaan pemasyarakatan di wilayah kerja Puskesmas Cempaka Banjarbaru.
Lifts of hypersurfaces on a Sasakian manifold to tangent bundles
Authors: KHAN Mohammad Nazrul Islam , DAS Lovejoy 
Published: December 2023

The aim of present paper is to introduce a Sasakian manifold immersed with Quartersymmetric semi-metric connection to tangent bundle. We deduce the relation between
Riemannian connection and Quarter-symmetric semi-metric connection to the tangent bundle on
a Sasakian manifold and obtain theorems on the totally geodesic and totally umbilical.
Pengaruh Pertumbuhan Pendapatan, Kebijakan Dividen, Kebijakan Hutang, Ukuran Perusahaan dan Kinerja Perusahaan terhadap Nilai Perusahaan Infrastruktur yang Terdaftar di BEI
Authors: Liong Felix , Cherry Irvania , Vanny Sheyla Tri 
Published: December 2023

The purpose of this research is to analyze the effect of sales growth, dividend policy, debt policy, company’s size, and company’s performance to infrastructure’s company value listed in Indonesia Exchange Stocks. The method of this research is clause method and use the purposive sampling method as the method to sampling the research’s population. The total of this research’s sample is 26 company. The result of the hypothesis test of the sales growth is the sales growth doesn’t affect the company’s value. The result is t-test 0.477 < t-table 1,666462. The result of the hypothesis test of the dividend policy is the dividend policy doesn’t affect the company’s value. The result is t-test 0.6389 < t-table 1,666462. The result of the hypothesis test of the debt policy is the debt policy affect the company’s value positively significant. The result is t-test 3,956 > t-table 1,666462. The result of the hypothesis test of the company’s size is the company’s size affect the company’s value positively significant The result is t-test 6,083 > t-table 1,666462. The result of the hypothesis test of the company’s performance is the company’s performance doesn’t affect the company’s value The result is t-test 1,080 < t-table 1,666462. The result of simultaneously test is sales growth, dividend policy, debt policy, company’s size, company’s performance affects the company’s value, with the test result is F-test 5,607862 > F-table 2,332.
Analisis Pemilihan Merchant Menggunakan Metode Segmentation Model Two Step Clustering pada Bank X
Authors: Riyani Sari , Kristianto Fajar , Wulandari Rayuli , Heikal Jerry , Purnawati Elisa 
Published: December 2023

Dalam penelitian ini data yang digunakan berasal dari transaksi pembelian dalam satu bulan nasabah Bank X yang dianalisis menggunakan metode two step cluster analysis. Penelitian ini bertujuan untuk mengidentifikasi kelompok nasabah yang memiliki karakteristik serupa dan merekomendasikan strategi dalam pemilihan merchant untuk membantu Bank X dalam menentukan target pasar yang tepat untuk meningkatkan kepuasan nasabah, dan meningkatkan transaksi serta memicu nasabah yang tidak aktif agar dapat aktif melakukan transaksi dengan program - program yang tepat sasaran guna meningkatkan kepuasan nasabah, dan mendorong pertumbuhan bisnis. Berdasarkan hasil pembahasan proses segmentasi cluster yang telah dilakukan pada aplikasi pengolahan data SPSS dan menggunakan algoritma two step cluster analysis, diperoleh 4 cluster yang memiliki persona dengan karakteristik dan preferensi yang berbeda-beda. Cluster 1 dengan label persona Foodie Cluster, sedangkan Cluster 2 dengan label persona Mobile Cluster (karena persona transaksinya di SPBU). Cluster 3 dengan label persona Groceries Cluster (karena berdasarkan data persona transaksi di supermarket/minimarket). Cluster 4 dengan label persona Fashion. Dari hasil analisis dan pembahasan 4 cluster yang ada, disimpulkan bahwa produk yang dominan transaksinya adalah pada segment food & beverage. Bank X memilih segment food & Beverage sebagai merchant target pasar yang tepat untuk meningkatkan kepuasan nasabah serta meningkatkan transaksi. “Cashback untuk Pembelian di Merchant Food & Beverage” sebagai value proposition dari Bank X.
Upaya Pencegahan Intoksikasi Merkuri Melalui Penyuluhan Pemanfaatan Herbal Bagi Masyarakat Kawasan Industri Sidoarjo
Authors: Dyah Wulandari Devyana , Santoso Andreas Putro Ragil , Salim Hotimah Masdan , Putri Endah Budi Permana 
Published: December 2023

Merkuri merupakan salah satu logam yang berbahaya dan dapat menyebabkan efek toksik pada manusia. Paparan merkuri dapat ditimbulkan akibat kegiatan yang dapat menghasilkan merkuri, seperti pembakaran batu bara perumahan, proses industri, insinerator limbah, penambangan merkuri, emas, dan logam lainnya, serta penggunaan kosmetik yang mengandung merkuri. Persenyawaan merkuri beracun bagi sistem saraf pusat dan perifer. Efek berbahaya akibat paparan merkuri terjadi pada sistem saraf, pencernaan dan kekebalan tubuh, paru-paru dan ginjal, dan dapat berakibat fatal. Garam merkuri anorganik bersifat korosif pada kulit, mata, dan saluran pencernaan, dan dapat menyebabkan toksisitas ginjal jika tertelan. Tujuan dari kegiatan pengabdian ini dilakukan untuk mengedukasi masyarakat yang tinggal di wilayah industri tentang bahaya intoksikasi merkuri serta pemanfaatan herbal untuk mengurangi bahaya paparan merkuri. Metode pelaksanaan kegiatan adalah penyuluhan. Evaluasi kegiatan dilakukan dengan memberikan kuisioner untuk mengukur peningkatan pemahaman mitra. Hasil kegiatan ini adalah peningkatan pemahaman masyarakat tentang bahaya intoksikasi merkuri serta peningkatan keterampilan masyarakat dalam memanfaatkan herbal untuk mengurangi efek toksik merkuri. Berdasarkan nilai signifikansi P = 0,01 (P < 0,05) menunjukkan bahwa terdapat perbedaan signifikan pemahaman masyarakat sebelum dan sesudah mengikuti kegiatan pengabdian ini. Kegiatan ini dapat meningkatkan pemahaman masyarakat mitra tentang intoksikasi merkuri dan meningkatan keterampilan masyarakat dalam memanfaatkan herbal untuk mengurangi efek toksik merkuri.
IMPLICAÇÕES DAS MUDANÇAS CLIMÁTICAS NAS URBANAS
Authors: Antonio Arcelia 
Published: December 2023

O presente artigo tem por objectivo analisar os impactos das mudanças climáticas nas zonas urbanas de Moçambique. Para a realização de este estudo recorreu-se a revisão da literatura, nomeadamente, artigos científicos, monografias, dissertações que abordam a cerca de mudanças climáticas e suas consequências. Moçambique localiza-se na África Oriental é quinto país do mundo mais vulnerável as mudanças climáticas, devido a sua localização geográfica, à sua costa, existência de zonas com altitude baixa em relação ao nível das águas do mar. Os fenómenos frequentes no país são: secas, ciclones, cheias. Ciente da gravidade o governo através Ministério da Terra e Ambiente tem levado a cabo várias acções de mitigação e efeitos das mesmos. A ocorrência de desastres naturais tem tido um impacto negativo na comunidade em várias níveis, nomeadamente: económico, agrícola, infraestrutural e humano. Moçambique tem registado nos últimos anos inundações nas áreas urbanas, lembrando que a urbanização ocorre de forma espontânea e desordenada
O PROTAGONISMO JUVENIL EM CONTEXTOS EDUCACIONAIS
Authors: Corrêa Shirlei de Souza , Santos João Derli de Souza , Simão Vera Lúcia 
Published: December 2023

A juventude vem demarcando um campo de mudanças, de lutas e de conquistas na sociedade. Tais mudanças vêm favorecendo a quebra de alguns paradigmas e, ainda, instalando outros. O próprio conceito de juventude que a sociedade contemporânea vem adotando, aponta um olhar além das questões biológicas, se ocupando, sobretudo, com o jovem que assume o desafio de agir, interagir e influenciar as estruturas existentes. Essa questão, a do protagonismo juvenil, quando discutida no contexto escolar, pode ganhar espaço e promover a ampla participação do jovem como verdadeiro ator da dinâmica escolar. Com o objetivo de perceber como os profissionais visualizam esta questão no interior das escolas, esta pesquisa, sob a metodologia do grupo focal, percebeu que estes movimentos são marcados mais pelas exigências legais - instituídas por documentos ou ações que são impostas às unidades escolares, do que pelos desejos e necessidades dos próprios jovens.
Palavras-chave: Protagonismo escolar. Juventude. Contexto escolar.

ABSTRACT
The youth has been demarcating a field of changes, fights and achievements in society. Such changes have been favoring the breaking of some paradigms and also installing others. The very concept of youth that contemporary society has been adopting points to a look beyond biological issues, focusing, above all, on young people who take on the challenge of acting, interacting and influencing existing structures. The issue of youth protagonism, when discussed in the school context, can gain space and promote the broad participation of young people as true actors in school dynamics. With the aim of understanding how professionals see this issue within schools, this research, using the focus group methodology, realized that these movements are marked more by legal requirements - established by documents or actions that are imposed on school units, rather than by the desires and needs of young people themselves.
Keywords: School protagonism. Youth. School context.
A adoção de dieta flexível frente a adoção de dieta restritiva: Uma revisão de literatura
Authors: Gonsalves Maria Eduarda Cabral Pellicione Sulz , Barros Marília Vieira de Camargo , Silva Maria Cláudia da 
Published: December 2023

O estudo observou mudanças na imagem corporal ao longo do tempo, especialmente entre adolescentes, influenciando a busca por corpos perfeitos e levando a escolhas por dietas restritivas. No entanto, uma abordagem mais flexível mostrou-se benéfica, promovendo comportamentos e resultados saudáveis e mantendo uma relação positiva com a comida. A pressão social por um corpo perfeito afetou a saúde mental, desequilibrando a relação das pessoas com a comida. A pesquisa comparativa entre dietas restritivas e flexíveis destacou os riscos do emagrecimento rápido e a realidade dos adolescentes em relação à comida, com foco em distorções de imagem, ressaltou que dietas restritivas não são ideais para a saúde global. A revisão bibliográfica abrangeu artigos científicos nacionais e internacionais de 1981 a 2023, utilizando diversas fontes, como BIREME, SciELO, CAPES, Google Scholar, livros, sites e PubMed. A coleta de dados ocorreu de março a novembro, com palavras-chave como "restrição alimentar", "dieta restrita", "dieta consciente", "seletividade com comida", "dietas da moda". Concluiu-se que dietas flexíveis contribuem para a saúde e o bem-estar, enquanto dietas restritivas podem causar traumas e medos alimentares. Restrições extremas muitas vezes resultam em emoções negativas, prejudicando a perda de peso saudável e uma relação positiva com a comida. A abordagem flexível, enfatizando equilíbrio, aspectos sociais e bem-estar, é considerada mais sustentável a longo prazo.
Desenvolvimento de VLPs (vírus like particle) como potencial vacina recombinante contra o vírus da dengue (DENV)
Authors: Reimberg Ariane Aparecida , Santos Gabrielle Ferrari , Silva Erika Gomes Vidal da , Simões Ermi , Almeida Beatriz Rodrigues de , Santos Deny Anderson dos 
Published: December 2023

A Dengue é uma doença grave, cuja erradicação ainda não foi alcançada em grande parte do mundo. A ausência de uma vacina eficaz e promissora para a prevenção da doença é um dos principais fatores que contribuem para essa situação. O desenvolvimento de Vírus Like Particles (VLPs) tem se mostrado uma estratégia promissora na busca por uma vacina eficaz contra a Dengue. Segundo a literatura, a dengue é caracterizada como um dos principais problemas de saúde pública mundial. Deste modo, é descrita como uma doença infecto contagiosa considerada a principal arbovirose que acomete humanos na atualidade. No entanto, nenhum tratamento específico ou vacina está disponível atualmente no mercado. Sendo assim, a produção de uma vacina multivalente capaz de induzir uma resposta imunológica contra os quatro sorotipos do vírus (DENV) seria a melhor opção para a prevenção da doença. Considerando que as vacinas de partículas semelhantes a vírus (VLP) tem alcançado resultados positivos na prevenção de outras doenças contagiosas, é possível questionar se este tipo de vacina não teria uma boa eficácia se aplicada a prevenção da dengue. Diante deste cenário, podemos compreender e justificar a importância deste trabalho, uma vez que estudos sobre aplicação da VLP na prevenção da dengue podem auxiliar no desenvolvimento de novos métodos de controle desta doença.
Kredit sindikasi dalam perspektif hukum dan peraturan perbankan (studi kasus pada pt bank dki)
Authors: Kharis Umardani Mohamad 
Published: December 2023

Penelitian ini dilakukan atas proyek PLTU Fast Track Program 10.000 MW PT PLN (Persero) yang dibiayai secara sindikasi oleh PT Bank DKI sebagai Lead Arranger dan Agent serta 23 (dua puluh tiga) Bank Pembangunan Daerah (BPD) di seluruh Indonesia yang tergabung dalam Asosiasi Bank Pembangunan Daerah (ASBANDA) pada 13 proyek PLTU dengan porsi IDR dan USD dalam 1 (satu) paket pendanaan dengan total kebutuhan pendanaan sebesar Rp. 4.848.047.835.643,- dimana kebutuahan pendanaan atas porsi USD dikonversi kedalam IDR dengan asumsi 1 USD = Rp. 12.000,-. Hasil dari penelitian ini adalah bagaimana konstruksi hukum dalam kredit sindikasi pada proyek tersebut mengingat jumlah dana yang cukup besar dan banyaknya proyek PLTU yang dibiayai, Bank DKI selaku arranger dan agent membentuk dua Perjanjian Kredit Sindikasi (PKS) No. 61 dan PKS No.62 yang mengatur hubungan hukum yang timbul diantara para pihak. Kewajiban kreditur dalam kredit sindikasi secara umum telah sesuai terlihat telah diatur pada klausula Perjanjian Kredit Sindikasi. Penerapan prinsip kehati-hatian perbankan atas pemberian kredit sindikasi pada proyek tersebut menjadi sangat penting mengingat mengenai legal lending limit atau Batas Maksimum Pemberian Kredit (BMPK) dari bank peserta sindikasi ada yang dilampaui namun pada kredit sindikasi ini dikecualikan dikarenakan adanya Surat Pengecualian BMPK yang diterbitkan oleh Bank Indoneisa serta dengan Surat Jaminan Pemerintah (Letter of Guarantee) yang diterbitkan oleh Menteri Keuangan selaku wakil Pemerintah Indonesia.
Sertifikat Halal Pada Produk Makanan Dan Minuman Memberi Perlindungan Dan Kepastian Hukum Hak-Hak Konsumen Muslim
Authors: Syafrida Syafrida 
Published: December 2023

Latar belakang masalah dengan adanya globalisasi, perdagangan bebas dan Masyarakat Ekonomi Asia (MEA) menyebabkan meningkatnyaÂ peredaran produk makanan dan minuman di masyarakat Indonesia. Indonesia adalah negara dengan penduduk agama Islam terbesar di dunia. Dalam Pasal 29 ayat (2) UUD RI Tahun 1945 disebutkan bahwaÂ â€œNegara menjamin tiap tiap penduduk untuk memeluk agamanya sesuai dengan kepercayaannyaâ€. Rumusan masalah tulisan ini adalah apa manfaat sertifikat halal produk makanan dan minuman yang diperdagangkan di masyarakat. Tujuan penulisan untuk mengetahui manfaat sertifikat halal pada produk makanan dan minuman yang diperdagangkan di msyarakat. Metode Penelitian yang digunakan dalam penulisan adalah penelitian Kepustakaan berupa data sekunder mengunakan bahan hukum primer, bahan sekunder dan bahan tersier. Kesimpulan dari tulisan ini untuk mendapat sertifikat halal pelaku usaha mengajukan permohonan sertifikat halal ke LPPOM MUI disertai data pendukungnya. LPPOM MUI membentuk Â Tim auditorÂ untukÂ melakukan audit pada saat proses produksi dan hasil audit disampaikan ke komisi Fatwa MUI untuk mendapat penetapan halal dan MUI mengeluarkan sertifikat halal, manfaat sertifikat halal pada produk yang diperdagangkan adalah untuk memberi perlindungan dan kepastian hukum hak-hak konsumen muslim terhadap produk yang tidak halal.