bluuebunny/crossref_metadata_2025_split huggingface dataset:
ปัจจัยที่มีผลต่อการประยุกต์นโยบาย ส่งเสริมความหลากหลาย ทางวัฒนธรรมของอาเซียน
Authors: ธำรงธัญวงศ์ สมบัติ , ไทยจงรักษ์ ณัฐพร , ขอบใจกลาง จุฬาภรณ์ 
Published: October 2023

วัตถุประสงค์ของงานวิจัยเพื่อศึกษาการนำนโยบายไปประยุกต์ใช้ของโรงเรียนในโครงการ Spirit of ASEAN ของ สพฐ. โดยศึกษาปัจจัยที่มีผลต่อการส่งเสริมความหลากหลายทางวัฒนธรรมในสถานศึกษา และเสนอแนวทางในการประยุกต์นโยบายส่งเสริมความหลากหลายวัฒนธรรมของอาเซียนโดยผ่านผู้บริหาร ครูอาจารย์ นักเรียน และผู้ปกครอง/ชุมชน
จากผลการวิจัยพบว่า โรงเรียนในโครงการ Spirit of ASEAN มีความรู้ ความตระหนัก และความเข้าใจเกี่ยวกับการส่งเสริมความหลากหลายทางวัฒนธรรมโดยผ่านหลักสูตรอาเซียน การเรียนการสอน ภาษาต่างประเทศ กิจกรรมการเรียนการสอน การสร้างเครือข่ายกับโรงเรียนในประเทศอาเซียน และ การมีศูนย์อาเซียนของตนเอง ในส่วนของปัจจัยที่มีผลต่อการส่งเสริมความหลากหลายทางวัฒนธรรม ประกอบด้วยปัจจัยด้านลักษณะส่วนบุคคล ได้แก่ การตระหนักรู้ ทัศนคติ และพฤติกรรม ของประชากรที่ศึกษา กลุ่มที่ 1 ผู้บริหาร พบปัจจัยสำคัญด้านการบริหารสถานศึกษาซึ่งเกี่ยวข้องกับการกำหนดนโยบาย กลุ่มที่ 2 ครู/อาจารย์ เกี่ยวข้องกับปัจจัยด้านการเรียนการสอนที่จะต้องถ่ายทอดคทวามรู้ด้านความหลากหลายทาง วัฒนธรรมให้กับนักเรียน กลุ่มที่ 3 นักเรียน เกี่ยวข้องกับปัจจัยด้านคุณลักษณะของผู้เรียนซึ่งนักเรียนต้อง เปิดใจยอมรับความแตกต่าง และกลุ่มที่ 4 ผู้ปกครอง/ชุมชน เกี่ยวข้องกับปัจจัยด้านการมีส่วนร่วมโดยการให้ความร่วมมือกับโรงเรียนเมื่อมีการจัดกิจกรรมต่างๆ และการร่วมในการกำหนดนโยบายในสถานศึกษาในส่วนของแนวทางการประยุกต์นโยบายส่งเสริมความหลากหลายวัฒนธรรมของอาเซียนสามารถแบ่งออกได้ 2 รูปแบบคือ รูปแบบที่ 1 การพัฒนาโรงเรียนในเมือง (Urban model) มีความหลากหลาย ด้านโครงสร้าง ประชากร อาชีพ เชื้อชาติ ศาสนา ดังนั้น ควรใช้ประโยชน์จากการเข้าถึงสื่อ และความสะดวกด้านเทคโนโลยี สารสนเทศ ในด้านการส่งเสริมความหลากหลายทางวัฒนธรรม รูปแบบที่ 2 การพัฒนาโรงเรียนในชนบท (Rural model) ควรใช้ทุนทางวัฒนธรรมให้เป็นประโยชน์
Triphenylamine‐Substituted Nile Red Derivatives with Efficient Reactive Oxygen Species Generation for Robust and Broad‐Spectrum Antimicrobial Photodynamic Therapy and Abscess Wound Healing
Authors: Dai Jianan , Fang Laiping , Fan Zhijin , Wang Xuan , Hua Jie , Dong He , Tu Yike , Li Shufang , He Kuo , Fang Jin , Hang Lifeng , Li Shumei , Wang Jin , Wang Wei , Ma Ping'an , Jiang Guihua 
Published: January 2025

AbstractInfections caused by drug‐resistant bacteria represent a major contributor to high mortality rates, underscoring the urgent need for effective non‐antibiotic drugs and alternative therapies. Antimicrobial photodynamic therapy (aPDT) emerges as an innovative treatment due to its minimal drug resistance. Herein, a series of Nile Red derivatives is synthesized by a donor engineering strategy. Notably, NTPA featuring triphenylamine (TPA) as the electron‐donating group, exhibited the highest production of reactive oxygen species (ROS). The enhanced electron donating‐accepting (D‐A) property effectively reduced the energy gap between S1 and T1 (ΔES‐T), facilitating intersystem crossing (ISC) with a larger spin‐orbit coupling (SOC) constant. Furthermore, the twisted conformation profoundly suppressed the quenching of ROS. As expected, an over 470‐fold increase in ROS production is observed, predominantly comprising type‐I ROS. NTPA nanoparticles (NPs) exhibited exceptional in vitro killing ability against various drug‐resistant bacteria, with inhibition efficiency even reaching 99.9%. In the methicillin‐resistant staphylococcus aureus (MRSA)‐induced abscess model, NTPA NPs facilitated complete wound healing within just 8 days following a single administration and irradiation, highlighting their exceptional bactericidal and wound‐healing promotion capabilities. Overall, this work inspired the construction of efficient Nile Red‐based type‐I photosensitizers (PSs) and the development of a new broad‐spectrum aPDT method for drug‐resistant bacteria treatment.
Sulfonic Acid Ligands Promote Surface Reconstruction of Perovskite Quantum Dots for High‐Performance Light‐Emitting Diodes
Authors: Wang Jiaxiang , Yang Zunxian , Chen Ye , Zhang Hui , Chen Yue , Bai Yuting , Jiang Xudong , Liu Benfang , Hong Jiajie , Fang Zhezhou , Gao Jinzhu , Zhou Zheyu , Yu Runsen , Song Xuanyao , Yuan Zhiyu , Guo Tailiang , Li Fushan , Chen Yongyi , Weng Zhenzhen 
Published: January 2025

AbstractPerovskite quantum dots (PQDs) have emerged as promising candidates for next‐generation high‐quality lighting and high‐definition displays due to their outstanding luminescence properties, characterized by a narrow emission spectrum and tunable color. However, during the purification process involving polar solvents, ligand detachment from the quantum dot surface often induces crystal defects, thereby compromising their long‐term stability. Herein, the effects of various post‐processing strategies on PQD performance are systematically explored, including the use of oleic acid (OA), didodecyldimethylammonium bromide (DDAB), and their combinations, alongside OA‐assisted synthesis. Furthermore, a synergistic post‐processing strategy based on DDAB‐NaMeS (sodium methanesulfonate) is proposed to elucidate the mechanism of ligand reconstruction on the quantum dot surface during purification. The resulting PQDs demonstrated excellent stability over a storage period exceeding one month, and the corresponding Quantum Dots Light‐Emitting Diodes (QLEDs) achieved a peak external quantum efficiency (EQE) of 9.82%, representing a 1.91‐fold improvement over standard devices. These QLEDs exhibited exceptional optoelectronic performance, underscoring their potential for application in other sulfonic acid ligands and perovskite‐based materials.
Anomalous Ultra‐Broadband Photoresponse Based on PdSe2 with Asymmetric Contact
Authors: Liu Mingli , Wang Wanqian , Zhang Xuemin , Shi Hongxiang , Wang SuoFu , Han Tao , Li Feng , Kang Lixing , Luo Wei , Shan Lei , Long Mingsheng 
Published: January 2025

AbstractAnomalous photoresponse with negative photoconductance (NPC) is rarely observed which is quite different from the common semiconductor with positive photoconductance (PPC) as the light can induce additional carriers. NPC effect is not widely studied because the performance of the NPC is limited and the device fabrication is uncontrollable. Here, a controllable way is reported to fabricate an anomalous photoresponse device through asymmetric metal contact with the PdSe2. A mirror electrode‐enhanced vertical asymmetric contact (VAC) PdSe2 device is designed. The VAC PdSe2 device demonstrated the NPC effect in an ultra‐broadband spectral range from 637 nm to the long‐wave infrared (LWIR) 10.6 µm. Notably, the device exhibits excellent uncooled mid‐wave infrared (MWIR) and LWIR detection ability with a high photoresponsivity (R) of 128.4 AW−1 and 38.2 AW−1, respectively. Furthermore, the lateral asymmetric contact (LAC) PdSe2 device is also investigated. The LAC PdSe2 device demonstrated competitive performance including high photovoltaic responsivity up to 0.22 AW−1 and external quantum efficiency (EQE) of 67.5%, fast photoresponse speed with rise time τr = 28.7 µs and decay time τd = 31.2 µs, and anisotropic dichroic ratio (γ) of ≈1.15. The results open a new platform for studying anomalous photoresponse with high performance in uncooled LWIR photodetection.
Eco‐Friendly and Scalable Preparation of High‐Efficiency Passive Daytime Radiative Cooling Film Based on Dual‐Layer Strategy
Authors: Wu Yingjie , Liu Bin , Zhang Renyan , Wang Yingeng , Pu Mingbo , Li Xiong , Luo Xiangang 
Published: January 2025

AbstractPassive daytime radiative cooling (PDRC), as a zero‐energy cooling technology, has attracted wide attention. It achieves high reflectivity in the solar band by scattering the incoming sunlight. According to Mie's theory, attaining elevated scattering efficiency necessitates a substantial refractive index disparity between the matrix material and the scattering particles in the PDRC film. Here, the study introduces barium titanate (BTO) nanoparticles as scattering particles, which have the highest theoretical refractive index among dielectric nanoparticles reported in the literature. A two‐layer strategy is implemented to mitigate the strong absorption of BTO nanoparticles in the ultraviolet (UV) band. Furthermore, using a liquid material as the matrix for the film and fabricating it via scrape coating technology enables an eco‐friendly and scalable preparation process. Ultimately, the obtained high‐efficiency PDRC (HE‐PDRC) film exhibits superb solar reflectance (0.948) and infrared atmospheric window emissivity (0.964). The HE‐PDRC film can achieve a cooling effect of ≈8 °C below the ambient temperature under clear weather conditions. The theoretical maximum cooling power is 87.5 W m−2 during the daytime and 125.2 W m−2 at night, respectively. This work paves the way for practical large‐scale applications of HE‐PDRC for human thermal comfort in buildings.
MaTableGPT: GPT‐Based Table Data Extractor from Materials Science Literature
Authors: Yi Gyeong Hoon , Choi Jiwoo , Song Hyeongyun , Miano Olivia , Choi Jaewoong , Bang Kihoon , Lee Byungju , Sohn Seok Su , Buttler David , Hiszpanski Anna , Han Sang Soo , Kim Donghun 
Published: January 2025

AbstractEfficiently extracting data from tables in the scientific literature is pivotal for building large‐scale databases. However, the tables reported in materials science papers exist in highly diverse forms; thus, rule‐based extractions are an ineffective approach. To overcome this challenge, the study presents MaTableGPT, which is a GPT‐based table data extractor from the materials science literature. MaTableGPT features key strategies of table data representation and table splitting for better GPT comprehension and filtering hallucinated information through follow‐up questions. When applied to a vast volume of water splitting catalysis literature, MaTableGPT achieves an extraction accuracy (total F1 score) of up to 96.8%. Through comprehensive evaluations of the GPT usage cost, labeling cost, and extraction accuracy for the learning methods of zero‐shot, few‐shot, and fine‐tuning, the study presents a Pareto‐front mapping where the few‐shot learning method is found to be the most balanced solution owing to both its high extraction accuracy (total F1 score >95%) and low cost (GPT usage cost of 5.97 US dollars and labeling cost of 10 I/O paired examples). The statistical analyses conducted on the database generated by MaTableGPT revealed valuable insights into the distribution of the overpotential and elemental utilization across the reported catalysts in the water splitting literature.
Galectin‐1‐Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs
Authors: Yu Xizhi , Qian Junjie , Ding Limin , Pan Caixu , Liu Xi , Wu Qinchuan , Wang Shuai , Liu Jianpeng , Shang Mingge , Su Rong , Guo Danjing , Xie Haiyang , Yin Shengyong , Zhou Lin , Zheng Shusen 
Published: January 2025

AbstractTumor‐associated macrophages (TAMs) are commonly considered accomplices in tumorigenesis and tumor development. However, the precise mechanism by which tumor cells prompt TAMs to aid in evading immune surveillance remains to be further investigated. Here, it is elucidated that tumor‐secreted galectin‐1 (Gal1) conferred immunosuppressive properties to TAMs. Specifically, patient specimens and a public database is first used to analyze the clinical relevance of Gal1 in hepatocellular carcinoma (HCC). Then, it is demonstrated that TAMs functioned as a critical mediator in the Gal1‐induced progression of HCC and the establishment of an immunosuppressive tumor microenvironment. Furthermore, RNA‐sequencing determined that Gal1 promoted the upregulation of chemokine (C‐C motif) ligand 20 (CCL20) in TAMs via activating the PI3K/AKT/NF‐κB pathway. Employing an anti‐CCL20 neutralizing antibody and Foxp3DTR mice, it is demonstrated that CCR6+Foxp3+ regulatory T cells (Tregs) recruited by Gal1‐induced TAMs contributed to reduced infiltration and dysfunctional state of CD8+ T cells, subsequently facilitating tumor progression. Targeting Gal1 dampened the secretion of CCL20 and inhibits the recruitment of Tregs, thereby activating anti‐tumor immunity and ameliorating anti‐PD‐1 resistance. Together, this findings revealed that Gal1‐induced TAMs recruited Tregs through the CCL20‐CCR6 axis. Inhibition of Gal1 improves the effectiveness of anti‐PD1 therapy, shedding important new light on the combination immunotherapy of HCC.
Recent Advances in Nanoenzymes Based Therapies for Glioblastoma: Overcoming Barriers and Enhancing Targeted Treatment
Authors: Wang Liyin , Gu Min , Zhang Xiaoli , Kong Tingting , Liao Jun , Zhang Dan , Li Jingwu 
Published: January 2025

AbstractGlioblastoma multiforme (GBM) is a highly aggressive and malignant brain tumor originating from glial cells, characterized by high recurrence rates and poor patient prognosis. The heterogeneity and complex biology of GBM, coupled with the protective nature of the blood–brain barrier (BBB), significantly limit the efficacy of traditional therapies. The rapid development of nanoenzyme technology presents a promising therapeutic paradigm for the rational and targeted treatment of GBM. In this review, the underlying mechanisms of GBM pathogenesis are comprehensively discussed, emphasizing the impact of the BBB on treatment strategies. Recent advances in nanoenzyme‐based approaches for GBM therapy are explored, highlighting how these nanoenzymes enhance various treatment modalities through their multifunctional capabilities and potential for precise drug delivery. Finally, the challenges and therapeutic prospects of translating nanoenzymes from laboratory research to clinical application, including issues of stability, targeting efficiency, safety, and regulatory hurdles are critically analyzed. By providing a thorough understanding of both the opportunities and obstacles associated with nanoenzyme‐based therapies, future research directions are aimed to be informed and contribute to the development of more effective treatments for GBM.
Is Social Jetlag Associated With Physical Fitness Among Spanish Adolescents? Insights From the EHDLA Study
Authors: Miño Camila , García‐Hermoso Antonio , Gutiérrez‐Espinoza Héctor , Olivares‐Arancibia Jorge , Yañéz‐Sepúlveda Rodrigo , Duclos‐Bastías Daniel , Smith Lee , López‐Gil José Francisco 
Published: January 2025

ABSTRACTBackgroundThe misalignment of sleeping times during weekdays/weekends (i.e., social jetlag) is particularly common among adolescents and plausibly associated with their physical fitness. However, literature on this topic is scarce. Therefore, this study aimed to investigate the association between social jetlag and physical fitness in Spanish adolescents.MethodsA secondary analysis was conducted on cross‐sectional data from the Eating Healthy and Daily Life Activities (EHDLA) study among 812 adolescents (54.9% girls) aged 12–17 years from the Valle de Ricote (Region of Murcia, Spain). Social jetlag was calculated from self‐reported data on bedtimes and wake times for weekdays and weekends. Physical fitness was evaluated with the Assessing the Levels of PHysical Activity and Fitness (ALPHA‐FIT) for children and adolescents and included cardiorespiratory fitness, muscular fitness, speed agility, and flexibility.ResultsThe analysis revealed significant negative associations between worse social jetlag and detrimental overall physical fitness (unstandardized beta coefficient [B] = −0.06, 95% confidence interval [CI]: −0.09, −0.02; p = 0.002), cardiorespiratory fitness (B = −1.28; 95% CI −2.22, −0.34; p = 0.008), and lower body muscular fitness (B = −2.01; 95% CI −3.90, −0.12; p = 0.038) after the adjustment for potential covariates (age, sex, socioeconomic status, physical activity level, sedentary behavior, nocturnal sleep duration, energy intake, and body mass index). In contrast with other fitness components, a significant positive association was identified between social jetlag and speed agility (B = 0.07; 95% CI 0.00, 0.14; p = 0.049).ConclusionsIn adolescents, social jetlag is significantly linked to poorer physical fitness, especially for cardiorespiratory fitness and lower‐body muscular fitness. Maintaining regular and well‐synchronized sleep could be crucial for optimizing physical health and preventing the decline of physical fitness during adolescence.
Genetic Services in Appalachia Conference Series
Authors: Kelly Kimberly M. , Dhumal Trupti , Scott Virginia G. , Falah Nadia , Kronk Rebecca , Terry Alissa Bovee , Graves Kristi , Pickarski Justine , Au Margaret 
Published: January 2025

ABSTRACTThis study examined the data generated as part of a seven‐session webinar series that focused on genetics care provision in the medically underserved, rural Appalachian region and examined how these services have adapted to challenging practice environments. Barriers and facilitators to care in our region were considered. Data included a baseline survey of registrants, transcripts of sessions, and feedback about sessions. We analyzed data with a sequential and concurrent mixed methods approach. Registrants (n = 137) were disproportionately healthcare providers with genetic services expertise (37.2%). Approximately half (43.8%) of registrants were from KY, WV, and TN in the central Appalachian region. Our baseline survey found that the most noted barriers were the cost of services, lack of providers, and access to care. The most common facilitator was telehealth. Analysis of transcripts identified barriers that were consistent with those noted in the baseline survey, but additional support and network opportunities were discussed to allow for learning across services. Numerous barriers to service delivery were noted; however, despite challenges, participants identified opportunities and resources in the community. These insights will inform a research agenda aimed at advancing genetics services in rural Appalachia, addressing challenges, and leveraging assets for improved healthcare access and outcomes.
A surgical orthotopic xenograft approach with immune response for colorectal cancer research
Authors: Hou Xiaoying , Li Xiaoxuan , Fang Qian , Deng Yufei , Wang Haiping , Sun Binlian , Zhang Chengliang , Du Hongzhi , Liu Yuchen 
Published: January 2025

AbstractThe high morbidity and mortality of colorectal cancer (CRC) is a major challenge in clinical practice. Although a series of alternative research models of CRC have been developed, appropriate orthotopic animal models that reproduce the specific clinical response as well as pathophysiological immune features of CRC are still lacking. In the current study, we constructed a CRC orthotopic xenograft model by implanting the tumor tubes at the colorectum of mice and monitored the model development using bioluminescence imaging. This model successfully recapitulates the clinical chemotherapy efficacy, including reduced total flux, tumor weight, and the expression of Ki67 after treatment of the first‐line chemotherapy regime of CRC (FOLFOX: oxaliplatin and 5‐fluorouracil/calcium folinate). The model also reproduced the immunosuppressive effect of FOLFOX, indicated by decreased infiltration of macrophages and increased Treg cells in tumor. Additionally, the orthotopic xenograft approach may be applied in immunodeficient NCG/NSG mice for constructing patient‐derived xenografts, and being used in clinical precision medicine and drug evaluation. We believe the current model is a successful surgical orthotopic xenograft approach for cancer research and deserves to be popularized, which will provide a convenient and efficient platform for in‐depth mechanism exploration of CRC and preclinical drug evaluation.
High‐Performance Overall Water Splitting Dominated by Direct Ligand‐to‐Cluster Photoexcitation in Metal–Organic Frameworks
Authors: Lin Qia‐Chun , Liao Wei‐Ming , Li Jiayu , Ye Bowei , Chen Da‐Tang , Zhou Xiao‐Xiang , Li Peng‐Hui , Li Meng , Li Ming‐De , He Jun 
Published: January 2025

AbstractExpanding the spectral response of photocatalysts to facilitate overall water splitting (OWS) represents an effective approach for improving solar spectrum utilization efficiency. However, the majority of single‐phase photocatalysts designed for OWS primarily respond to the ultraviolet region, which accounts for a small proportion of sunlight. Herein, we present a versatile strategy to achieve broad visible‐light‐responsive OWS photocatalysis dominated by direct ligand‐to‐cluster charge transfer (LCCT) within metal–organic frameworks (MOFs). Three synthesized OWS MOFs, namely Fe2MCbz (M2+ = Mn2+, Co2+, Ni2+), exhibited intrinsic OWS capability without the requirement for extra photosensitizer or sacrificial agent or cocatalyst. Among these, Fe2NiCbz was identified as the superior performer, and when dispersed with polyacrylonitrile nanofibers using electrospinning technology, it achieved the highest OWS rates of 170.2 and 85.1 μmol g−1 h−1 for H2 and O2 evolution, surpassing all previously documented MOF‐based photocatalysts. Experimental and theoretical analyses revealed that direct LCCT played a crucial role in enhancing the photocatalytic efficiency, with exceptional performance of Fe2NiCbz attributed to its well‐optimized energy level structures and highly efficient charge transfer mechanism. This work not only sets a benchmark in OWS MOF photocatalysts but also paves the way for maximizing solar spectrum utilization, thereby advancing renewable hydrogen production strategy.
Co‐digestion of olive mill wastewater and municipal solid waste landfill leachate promotes medium‐chain fatty acids and hydrogen production
Authors: Saadoun Lamia , Campitelli Alessio , Kannengiesser Jan , Stanojkovski Daniel , Mandi Laila , Ouazzani Naaila 
Published: January 2025

AbstractThe management of olive mill wastewater (OMWW) and municipal solid waste landfill leachate presents a significant challenge due to their high concentrations of organic matter and phenolic compounds. These substances complicate treatment processes, hinder their potential use in agriculture, and inhibit key biological processes such as acetogenesis and methanogenesis. Nonetheless, an urgent need remains to develop a sustainable solution for managing hazardous waste while generating valuable resources. This research hypothesizes that co‐digestion can enhance the production of medium‐chain fatty acids (MCFAs) and hydrogen (bioenergy), which are target molecules due to their wide range of applications. Several batch reactor experiments were conducted to investigate the co‐digestion of OMWW and landfill leachate at varying ratios, with and without the addition of ethanol as an electron donor. The results show 30% landfill leachate:70% OMWW, supplemented with ethanol, achieved the highest MCFA production, predominantly of hexanoic acid, along with significant hydrogen generation. Finally, co‐digestion of OMWW and landfill leachate demonstrated significant potential for producing both MCFAs and hydrogen, offering a solution to the environmental issues posed by these effluents and promoting the circular economy.