bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgery Outcomes of Glaucoma Drainage Device Implantation in Refractory Glaucoma Patients at Sardjito General Hospital
Authors: Saputra Yuandani , Jati Krisna Dwi Purnomo , Ekantini Retno , Gani Tatang T 
Published: February 2024

Introduction & ObjectivesGlaucoma drainage device (GDD) implantation was an effective surgical procedure in treatinguncontrolled intraocular pressure (IOP) of glaucoma patients in certain complicated conditions. GDDimplants were classified into valved and non-valved in which its surgical outcomes in different typesof device and various etiologies were not similar. This study aimed to evaluate the surgery outcomesof GDD implantation in patients with refractory glaucoma at Sardjito General Hospital.
MethodsAll 12 eyes of 11 patient’s medical records who underwent GDD implantation during 2022 at SardjitoGeneral Hospital was reviewed. Baseline data include age, gender, eye laterality, type of glaucoma,IOP and visual acuity. The IOP and visual acuity (LogMAR) were measured at week 1, month 1, 2and 3. Type of GDD implants, postoperative glaucoma medications, complications and need forfurther glaucoma surgery were documented.
ResultsThe mean IOP at baseline was 44 ± 14.2 mmHg with 3.4 ± 0.6 glaucoma medications. It decreasedafter surgery into 19.1 ± 11.2 mmHg (p=0.003) at 3 months follow up with 0.7 ± 1.7 (p=0.002)glaucoma medications. The mean initial visual acuity was 1.9 ± 0.6 and changed insignificantly to1.7 ± 0.8 (p=0.624) at last follow up. Six eyes (50%) were implanted with valved implant. The mostcommon early postoperative complications were recurrent high IOP (4 eyes, 33.3%) associated toripcord of non-valved implant (p=0.025). Five eyes (41.7%) needed additional surgery related tonon-valved implant type (p=0.003).
ConclusionGDD implantation especially valved type appears to be safe and effective surgical option in treatingrefractory glaucoma patients.
Microinvasive Glaucoma Surgery using Goniotomy as A Potential Surgical Treatment Modality in Indonesia: A Descriptive Study and Literature Review
Authors: Wetarini Krisnhaliani , Rahayu Ni Kompyang , Kusumadjaja I Made Agus , Suryaningrum I Gusti Ayu Ratna 
Published: February 2024

Introduction & ObjectivesMicro-invasive glaucoma surgery with goniotomy is a recent surgical treatment modality that targetsthe trabecular outflow to maintain intraocular pressure. This study aims to describe the clinicaloutcomes of excisional goniotomy using KDB and to review the published literature regarding amodified goniotomy technique as a potential surgical treatment modality in Indonesia.
MethodsA cross-sectional descriptive study was conducted in patients that underwent goniotomy stand-aloneor combined with cataract surgery. Main outcome parameters consist of visual acuity, intraocularpressure (IOP), number of glaucoma medications, and complications during post-operative follow-up.
ResultsA total of 7 patients (8 eyes) were included in the study, consisting of 5 (71,4%) males and 2 (28,6%)females. The mean age of the subjects was 47.7 years. Subjects consisted of primary,pseudoexfoliative, steroid-induced, and angle-recess glaucoma. Mean pre-operative IOPmeasurements showed 20.74 mmHg with visual acuity consisting of 1 (14.3%) mild visualimpairment and 7 (85.7%) severe visual impairment. Postoperatively there was progressiveimprovement in the mean IOP to 13.81 and 11.31 mmHg on first-day and one-week follow-up,respectively. Visual improvement was observed in 2 (28.5%) with mild visual impairment, 3 (42.6%)with severe visual impairment, and 2 (28.5%) with hand movement due to complications of cornealedema following phacoemulsification. A week later, visual acuity improved to 4 (57.1%) with mildvisual impairment and 3 (42.9%) with moderate visual impairment.
ConclusionGoniotomy is a simple surgical method that may be applied in Indonesia as a novel technique toprovide an effective intraocular pressure-lowering effect.
SECONDARY GLAUCOMA AFTER VITREORETINAL SURGERY: A RETROSPECTIVE OBSERVASIONAL STUDY
Authors: Gunawan Liani Mulasari , Rifada R. Maula , Gustianty Elsa , Umbara Sonie 
Published: February 2024

Introduction & ObjectivesSecondary glaucoma is the most common complication after vitreoretinal surgery. Pars PlanaVitrectomy (PPV) is a common surgical procedure aimed at removing vitreous gel and replacing itwith variety of substances denominated tamponades. Vitreous removal and replacement may causeincreased intraocular pressure (IOP). The IOP can be reduced with medical treatment or surgery.The purpose of this study is to describe the characteristics of secondary glaucoma after vitreoretinalsurgery in National Eye Center Cicendo Hospital from January 2019 - December 2020.
MethodsThis study was a retrospective descriptive study which data were obtained from medical records.Data such as age, gender, vitrectomy tamponades, IOP, onset of glaucoma, and glaucoma treatmentwere collected.
ResultsOne hundred fifty-three eyes were referred to Glaucoma Unit with increasing IOP after vitreoretinalsurgery. PPV with tamponade was done in 141 eyes (92.16%) and silicone oil (SO) 1000 centistokes(cSt) was the most used tamponade in 101 eyes (66.07%). Secondary glaucoma with open angle wasthe most common type in 124 eyes (81.04%). Secondary glaucoma developed in 4-7 weeks aftersurgery, with the highest IOP recorded at 31-40 mmHg. The IOP decreased after SO evacuation withinitial glaucoma treatment in 121 eyes (79.09%), and glaucoma surgery was performed in 32 eyes(20.91%).
ConclusionSilicon oil as a tamponade agent after PPV may cause rise IOP in the post-operative period.Evacuation SO needs to be done after retinal adhesion to prevent secondary glaucoma. Therefore,timely detection and anti-glaucoma treatment are important to decreased IOP, or filtration surgerycan be performed.
INTRAOPERATIVE MITOMYCIN-C, 5-FLUOROURACIL, RETROBULBAR TRIAMCINOLON ACETONIDE, IS IT EQUALLY EFFECTIVE TO DECREASE INTRA OCULAR PRESSURE AFTER TRABECULECTOMY?
Authors: Sari Yessi Primanda , Ekantini Retno , Gani Tatang Talka , Jati Krisna Dwi Purnomo 
Published: February 2024

Introduction & ObjectivesTo evaluate the effect of mitomycin-C (MMC), 5-fluorouracil (5-FU), and retrobulbar triamcinoloneacetonide (TA) on the surgical result of trabeculectomy.
MethodsAll consecutive trabeculectomies with releasable sutures performed in Sardjito General Hospitalbetween January 2022 and December 2022 were retrospectively reviewed from medical records.Patients without any intraoperative metabolite (control group, n=5) were compared to those withretrobulbar TA (n=5), MMC group (n=19), and 5-FU group (n=11) in terms of surgical success.Successful surgery results were defined as IOP between 5 - 21 mm Hg without any furthermedications or surgical intervention and fewer complications.
Results40 eyes of 35 patients (15 male, 25 female, mean age 52.4 years) were included in the study. Patientwas observed until post-operation day (POD) 90. There were no significant differences of intraocularpressure at POD 1, 7, 30, 60, and 90 between control group compared to TCA, MMC, and 5-FUgroup. Intraocular pressure pre- and post-operation in each group was significantly different(p<0.05). The lowest mean intraocular pressure of POD 90 was in 5-FU group (13.64 ± 4.08).Complication after trabeculectomy in TCA group was 21%, MMC group was 27%, 5-FU group was10%, and control group was 42%.
ConclusionMMC, 5-FU, and TCA in this study are equally effective to decrease IOP after trabeculectomy.
ASSOCIATION BETWEEN ESTROGEN LEVELS WITH INTRAOCULAR PRESSURE IN PRIMARY OPEN ANGLE GLAUCOMA PATIENT
Authors: Rambe Alvin , Sari Masitha Dewi , Aldy Fithria , Ashar Taufik 
Published: February 2024

Introduction & ObjectivesThere are studies that state that estrogen deficiency can exacerbate visual disturbances in glaucomapatients. To determine the relationship between estrogen levels and intraocular pressure (IOP) inpatients with POAG.
MethodsThis study used a case-control design in 30 POAG patients who came to the OphthalmologyPolyclinic at the University of North Sumatra Hospital and Network Hospital. The data collectionmethod in this study used a consecutive sampling technique starting from February 2022 until thesample was filled. The inclusion criteria in this study were all women with POAG who were ?40years old and willing to be the research sample. The exclusion criteria for this study were patientswith a history of secondary glaucoma or a history of optic nerve disease, a history of ocular surgery(except cataracts), a history of orbital trauma, menstrual disorders, or currently on hormonaltherapy, a history of systemic or autoimmune disease. Data is then collected and analyzed.
ResultsOf the 30 patients with POAG, the majority were aged 45-65 years (46.7%) with an average age of55.87(±12.91) years and had suffered from POAG for an average of 1.62(±2.08) years. The averagepatient had an intraocular pressure of 25.07(±6.12) mmHg, MD -12.99(±8.28) dB, VCDR0.78(±0.13) mm, and estrogen levels 2.47(±2.11) pg/dL. There was no significant relationshipbetween estrogen levels and intraocular pressure (p=0.851).
ConclusionThere was no significant association between estrogen levels and intraocular pressure in patientswith POAG.
TWO YEARS DESCRIPTIVE STUDY OF MACULAR HOLE PATIENTS OPERATED IN DR. KARIADI GENERAL HOSPITAL, SEMARANG
Authors: Partomuan Andreas Tigor , Wildan Arief 
Published: February 2024

Introduction & ObjectivesMacular hole (MH) is a vitreomacular interface disorder that could cause visual impairment. Clinicalcharacteristics of MH are important for predicting MH treatment outcomes. This study purpose wasto describe MH patients’ characteristics and postoperative outcomes in Dr. Kariadi Hospital.
MethodsA retrospective study held on January 2021–December 2022 utilizing patients’ medical records.Preoperative data: sex, age, symptoms, duration of symptoms, origin, preoperative visual acuity(VA), modified Gass classification stage, macular hole index (MHI), and hole forming factor (HFF)were obtained. Postoperative outcomes data: postoperative VA and anatomical closure were alsocollected.
Results20(20 eyes) patients were obtained, with 14(70%) female, 12(60%) aged >60 years old, 13(65%)metamorphopsia, 12(60%) central visual loss, 10(50%) preoperative VA 6/24-6/60, 10(50%) durationof symptoms <3 months, and 16(80%) idiopathic origin. OCT (Ocular Coherence Tomography)findings revealed base diameter mean was 780,7 um(+ SD 312). 13 patients (65%) stage 3 of MH,12(60%) MHI <0,5, 12(60%) HFF > 0,9. All patients underwent MH surgery procedures.Postoperative examination showed 10 patients(50%) with VA 6/6-6/20. 11(100%) with preoperativeVA>6/60, 10(100%) with duration of symptoms <3 months, 8(100%) with MHI > 0,5, and 11(100%)with HFF > 0,9 had improved visual acuity and anatomical closure. It also revealed 17(85%) hadanatomical closure.
ConclusionThe most common characteristics found in MH patients were female sex, age >60 years old, anddisorder of idiopathic origin. Preoperative VA, duration of symptoms <3 months before surgery, MHI> 0,5, and HFF > 0,9 were positive prognostic factors for better postoperative functional andanatomical outcomes.
REDUCTION OF INTRAOCULAR PRESSURE POST MICRO PULSE TRANSSCLERAL CYCLOPHOTOCOAGULATION IN REFRACTORY GLAUCOMA PATIENTS
Authors: Rahayu Annisa , Gustianty Elsa , Knoch Andrew M.H , Rifada Maula , Umbara Sonie 
Published: February 2024

Introduction & ObjectivesCyclodestructive laser is one of the last resource managements for refractory glaucoma, especiallywith low visual potential. Conventional laser using CW-TSCPC showed unstable IOP reduction withcollateral tissue damage. MP-TSCPC using on and off cyclic waves is considered to have a gooddegree of IOP reduction and fewer complications. The purpose of this study is to assess the IOPreduction after the MP-TSCPC procedures for patients with refractory glaucoma.
MethodsThis is a prospective observational study for refractory glaucoma patients treated with the MPTSCPClaser procedure. Measurement of IOP was carried out preoperatively and on postoperativedays 1, 7, and 30 with the gold standard Goldmann applanation tonometry.
ResultsA total of 33 eyes from 33 patients were enrolled in this study. The mean baseline IOP was 48.45 ±12,79 mmHg. The mean degree of IOP reduction on follow-up days 1, 7, and 30 were 14.39 ±23.52%, 45,83 ± 24,80 and 27.09 ± 23.86% respectively. On the 30th day after the laser treatment,no complications were observed. The number of anti-glaucoma medication was reduced from 2.39 ±0.49 at the baseline to 1.91 ± 0.58 at one month follow up.
ConclusionMicro-pulse transscleral cyclophotocoagulation laser showed a good degree of IOP reduction with noincidence of complication observed at day 30.
Bevacizumab vs Ranibizumab in Macular Edema due to Retinal Vein Occlusion: Short-term Outcomes
Authors: KURNIAWAN CHALID 
Published: February 2024

Introduction & ObjectivesBevacizumab or Ranibizumab was widely used as therapy for macular edema (ME) in retinal veinocclusion (RVO) and diabetic retinopathy. The purpose of this study was to comparing short-termoutcomes for patients who received intravitreal Bevacizumab (IVB) injection or Ranibizumab (IVR)for ME due to RVO
MethodsThis was observational, cross sectional study comparing patients received IVB or IVR. Primaryoutcomes data (visual acuity and central macular thickness/CMT) and secondary outcomes data(number injection and intra ocular pressure/IOP) were collected at baseline and 3 months afterinjection
ResultsThere were 4 eyes in each group. There were no significant difference in mean change of visualacuity (-0.275±0.25 vs -0.15±0.5 logMAR; p=0.676) and CMT (-171.50±129.08 vs -98.25±37.67 um;p=0.345) in IVB vs IVR groups. There were also no significant difference in mean change of IOP(2±2.16 vs 2±4.69 mmHg; p=1) and number of injection (2.25±0.50 vs 1.75±0.9; p=0.401 ) in bothgroups.
ConclusionIn short-term both IVB and IVB have relative similar outcomes on increasing visual acuity anddecreasing CMT in ME due to RVO
Relationship between Serum Homocysteine Levels and Manganese Superoxide Dismutase (MnSOD) on Retinal Nerve Fiber Layer (RNFL) Thickness in Diabetic Retinopathy and Non-Diabetic Retinopathy Patients
Authors: Nurrakhmah Rini , Delfi  , Lubis Rodiah Rahmawaty , Virgayanti Vanda 
Published: February 2024

Introduction & ObjectivesDiabetic retinopathy is a visual disorder caused by abnormalities in the retina, where there is aprogressive microangiopathy characterized by damage and blockage of fine blood vessels, resultingin impaired nutrition of the retina. This study is to find out the relationship between serumhomocysteine levels and MnSOD on retinal nerve fiber layer (RNFL) thickness in diabeticretinopathy and non-diabetic retinopathy patients.
MethodsThis study is an analytic observational case-control study with a total of 31 subjects for each group.3cc of venous blood samples were taken to assess the serum levels of homocysteine and MnSOD andthen analyzed by ELISA method in the integrated laboratory of the USU Medical Faculty.
ResultsThere was a significant difference in Avg RNFL and Nasal RNFL thickness between the two groups(p=0.015) with the mean Avg RNFL thickness being 100.94 (SD=17.04) and the mean RNFL nasalthickness being 90.16 (SD=33.68). The highest MnSOD levels were found in non-diabeticretinopathy subjects with a mean of 142.77 (SD=101.77). There was no significant relationshipbetween homocysteine and thickness of superior RNFL (p=0.346), inferior RNFL (p=0.292),temporal RNFL (p=0.109), nasal RNFL (p=0.190). However, a significant association was foundbetween homocysteine and Avg RNFL (p=0.007).
ConclusionIn the group of cases of diabetic retinopathy, a significant relationship was found between Hcy andAvg RNFL (p=0.007). An increase in serum homocysteine levels will be followed by a decrease in thethickness of the Avg RNFL.
Theory and practice of the deferrization and demanganation technology: experience of the Republic of Belarus and Russian Federation (part 1)
Authors: Рублевская О.Н. , Гвоздев В.А. , Портнова Т.М. , Сазанова Н.И. , Давидович А.С. , Витковская Р.Ф. , Нестерова Т.М. 
Published: February 2024

Статья посвящена анализу методов удаления железа и марганца из подземных вод на объектах водоподготовки с обоснованием каждого этапа технологической схемы на основе физико-химических закономерностей процессов. Представлены сведения о факторах, влияющих на состав подземных вод, теоретические основы физико-химических процессов обезжелезивания и деманганации, инновации в области развития технологий. Приведена оценка эффективности действующих станций производства питьевой воды Республики Беларусь и РФ. Статья, приуроченная к 150-летию УП «Минскводоканал», подтверждает взаимодействие водоканалов двух соседних государств, которые имеют аналогичные геохимические характеристики водоносных грунтов.
The paper dwells upon the analysis of methods for removing iron and manganese from groundwater at water treatment facilities with the justification of each stage of the process flow scheme based on the physical and chemical process patterns. Information is presented on the factors effecting the composition of groundwater, on the theoretical foundations of the physical and chemical processes of deferrization and demanganation, and on the technology innovations. An estimation of the efficiency of the operating water treatment facilities in the Republic of Belarus and Russian Federation is given. The paper confined to the 150th anniversary of the Minskvodokanal Unitary Enterprise corroborates the cooperation of water utilities of the two neighboring states that have similar geochemical characteristics of the aquifers.
Pelatihan Manajemen Pariwisata dan Ekonomi Kreatif di Kabupaten Bandung
Authors: Setiawan Agustina , Rohayatin Titin , Nurdin Iing , Wulan Widuri Wulandari 
Published: February 2024

Desa yang ada di Kabupaten Bandung memiliki peluang untuk mewujudkan manajemen pengelolaan pariwisata dan ekonomi kreatif. Namun, sampai saat ini belum seluruhnya desa di Kabupaten Bandung dapat mewujudkannya. Pelatihan ini bertujuan untuk meningkatkan pengetahuan aparatur pemerintah desa dalam manajemen pariwisata dan ekonomi kreatif. Metode pelaksanaan yaitu dengan cara pemberian materi tentang manajemen pariwisata dan ekonomi kreatif, pelatihan pengelolaan/ workshop manajemen pariwisata dan ekonomi kreatif dan Focus Group Discussion (FGD) dengan para aparatur pemerintah Desa terkait manajemen pariwisata dan ekonomi kreatif se-Kabupaten Bandung. Hasil dari FGD, ditemukan masih ada beberapa desa yang memiliki potensi, namun belum mampu untuk dikembangkan menjadi desa wisata, ataupun mewujudkan ekonomi kreatif. Hal ini dikarenakan keterbatasan anggaran, pengetahuan, dan infrastruktur dari desa. Untuk itu, diperlukan pelatihan lanjutkan dengan tema yang sama.
Kata Kunci: Manajemen; Ekonomi Kreatif; Pemerintah Desa
influence of training, discipline, and innovation on the performance of members of the Regional National Crafts Council (Dekranasda) in Tanjungpinang City: A quantitative study
Authors: Afriyani Nur , Indrayani Indrayani , Indrawan Mohamad Gita , Wibisono Cablullah , Ngaliman Ngaliman 
Published: February 2024

Purpose: This Purpose is The study examines the impact of innovation, discipline, and training on Tanjungpinang City members of the Regional National Crafts Council (Dekranasda) performance.
Research methodology: The Methodology used a quantitative approach with a descriptive quantitative design and surveyed 130 Dekranasda members. The data was collected through questionnaires and analyzed using SEM-PLS and path analysis.
Results: The Result found that training has a significant influence on motivation, discipline, and performance. Discipline and innovation also have a significant influence on motivation and performance. The study also found that motivation has a significant influence on performance. The study concludes that training, discipline, and innovation are important factors in improving the performance of Dekranasda members.
Limitations: Recognizing inherent limitations, this study acknowledges constraints related to sample size and potential biases in self-reported data. These limitations inform the boundaries of the generalizability of the findings.
Contribution: This research contributes valuable empirical evidence to the field, shedding light on the nuanced interactions between training, discipline, and innovation within the specific context of Dekranasda. The findings offer practical implications for enhancing the performance of regional crafts councils.
Implementation: The implementation is Training has a major impact on performance, discipline, and motivation. Motivation and performance are also greatly impacted by creativity and discipline. The study also discovered a strong correlation between motivation and performance. The study concludes that training, discipline, and innovation are important factors in improving the performance of Dekranasda members.
Comparison of Black-Scholes Models Using Historical Volatility and Garch Volatility in Collar Strategy as Hedging Efforts for Towr and Tbig Stocks
Authors: Rikumahu Brady , Akhmad Mu’arif Fandhi 
Published: February 2024

Purpose: Telecommunications has undergone significant development in accordance with the times. Telecommunications narrows distances and facilitates information access. The infrastructure within telecommunications plays a crucial role in the establishment and continuity of communication. Investment involves the allocation of money or capital with the aim of gaining profit. Stocks are one of the instruments in investment; besides gaining profits, investors also face the risk of experiencing losses. Therefore, it is necessary to provide value protection to stocks owned by investors. The objective of this research is to explore the implementation of option contracts in the Black-Scholes model using Historical Volatility and GARCH Volatility with a collar strategy.
Research methodology: The data used in this study consists of the closing prices of TOWR and TBIG stocks from the period of 2011-2022. The research findings conclude that, for TOWR stocks under non-crisis conditions with a maturity of 3 months, the Black-Scholes model with GARCH Volatility performs better than the model with Historical Volatility in every scenario. Meanwhile, for TOWR stocks under crisis and non-crisis conditions with maturities of 1 and 3 months, the Black-Scholes model using Historical Volatility is superior to the model using GARCH Volatility in one of the scenarios.
Results: In the case of TBIG stocks under crisis conditions with a maturity of 3 months, the Black-Scholes model with GARCH Volatility outperforms the model with Historical Volatility in all scenarios. However, under the conditions of a 1-month maturity and non-crisis conditions for 1 and 3 months in one scenario, the Black-Scholes model using Historical Volatility is superior to the model using GARCH Volatility.
Contribution: The contribution is Investment involves the allocation of money or capital with the aim of gaining profit.