bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enabling 4.5 V Solid Polymer Batteries through a 10 µm, Crosslinked Polyether Electrolyte
Authors: Zhang Min , Wang Helin , Shao Ahu , Wang Zhiqiao , Tang Xiaoyu , Li Shaowen , Liu Jiacheng , Ma Yue 
Published: February 2024

AbstractThe implementation of solid polymer electrolytes (SPEs) in energy‐dense batteries faces severe challenges including sluggish ionic diffusion, oxidation tendency at the cathode interface, dendrite protrusion from the metallic anode, as well as the technological incompatibility with the layer stack‐up cell assembly. Herein, an in‐situ polymerization strategy is presented to deal with above dilemma for the solid battery prototyping. The in situ cross‐linked poly(ethylene glycol) diglycidyl ether is embedded within the nanocellulose framework, endowing SPE membrane with the reinforced mechanical strength (11.31 MPa) at the thickness of 10 µm as well as superior ionic conductance (150 mS). After a rigorous selection, the sacrificial triphenylphosphine additive preferentially oxidizes on the LiNi0.8Mn0.1Co0.1O2 (NCM811) cathode to form the cathode electrolyte interface during the formation charging. Concurrently, the solvated zinc(II) bis(trifluoromethylsulfonyl)imide constructs the polyether/LiZn mosaic layer on the Li foil, which effectively promotes interfacial cation diffusion and horizontal deposits propagation. By pairing the polymerized SPE with the thin‐layer Li foil (50 µm) and the NCM811 cathode (25 mg cm−2), the 94 mAh pouch‐format cell can realize a gravimetric/volumetric energy density of 397.5 Wh kg−1 and 1197.6 Wh L−1, high‐voltage tolerance till 4.5 V, and robust cyclability (95.1% capacity retention for 200 cycles).
Coupling atomic layer deposition with supercritical fluid processing to provide a highly C3H6‐selective ZIF‐8 membrane
Authors: Liu Liangliang , Hu Wenjing , Sun Yanwei , Ji Taotao , He Yongfu , Yu Kunpeng , Wu Mingming , He Gaohong , Liu Yi 
Published: February 2024

AbstractZeolitic Imidazolate Framework‐8 (ZIF‐8) membrane is well recognized for its great capability in efficient C3H6/C3H8 separation, and their sustainable fabrication is extremely advantageous for batch production and commercial application. In this study, a solvent‐free protocol was developed for sustainable production of ZIF‐8 membranes with exceptional C3H6/C3H8 selectivity through combining atomic layer deposition (ALD) technique with in situ supercritical fluid (SCF) processing. Experimental results indicated that maintaining appropriate deposition number and conducting SCF processing in gas‐like supercritical carbon dioxide region were crucial for obtaining ZIF‐8 membranes with excellent C3H6/C3H8 selectivity (~185), one of the highest among ZIF‐8 membranes reported in the literature. Noteworthy, not only residual 2‐methylimidazole ligands along with vented gaseous CO2 could be fully recycled and repetitively utilized, but also obsoleting ZIF‐8 membranes could be effectively patched upon SCF‐based treatment. The above‐mentioned solvent‐free protocol holds great application prospects for sustainable production of diverse high‐performance metal–organic framework membranes.
Role of mechanotransduction on decision making for treatment of chronic wounds
Authors: McElvain Kelly , Gopalakrishnan Sandeep , Dabagh Mahsa 
Published: February 2024

AbstractThe objective of this study is to take an initial step to determine and interpret the extents to which biophysical wound dressing properties impact mechanotransduction within a wound tissue. Current experimental techniques make it challenging to investigate many of the complexities of the wound healing process. Thus, the purpose of this study is to begin with computational models and theoretical descriptions that propose predictions and explanations of the role of various mechanical wound dressing characteristics on mechanotransduction in wound tissues. Three‐dimensional models of wound tissue and wound dressings have been developed to analyze how von Mises stresses are distributed within the tissue models. Our results show that shorter ellipsoid dressings lead to highest stresses within the wound tissue where dressing's thickness and stiffness don't show a significant impact. When using a rectangular dressing, shorter, softer, thinner ones lead to high stress transmission to a wound tissue.
Mothers and sportsmen: The gendered and racialised nature of role model selection for Aboriginal and/or Torres Strait Islander youths
Authors: Guerzoni Michael Andre , Prehn Jacob , Peacock Huw 
Published: February 2024

AbstractThis article seeks to understand who Aboriginal and Torres Strait Islander children select as role models, and the reasons underlying these choices. Drawing data from Wave 8 of the Longitudinal Study of Indigenous Children, it comprises a sample of 307 children (169 male and 138 female) aged between 10.5 and 12 years at the time of data collection. Content analysis was used to analyse survey responses regarding two questions pertaining to role models, the analytical process being underpinned by Indigenous standpoint theory. The findings show that participants tended to select role models correlating with their gender and who were Indigenous or people of colour. For boys, most selected Indigenous sportsmen, whilst girls more evenly selected mothers, women from the entertainment industry, and sportswomen. The reasons why these individuals were selected were similar for boys and girls: the role model's ability, mastery and/or competency in a given field. These findings are important for educators and schools in guiding Aboriginal and Torres Strait Islander youths in their educational and career choices, and for policymakers in creating campaigns and pathways into fields where Indigenous persons are underrepresented.
Patient perspectives on chronic rhinosinusitis in cystic fibrosis: Symptom prioritization in the era of highly effective modulator therapy
Authors: Liu Christine M. , Han Ethan J. , Fischer Jakob L. , Mace Jess C. , Mattos Jose L. , Markarian Karolin , Alt Jeremiah A. , Bodner Todd E. , Chowdhury Naweed I. , Eshaghian Patricia H. , Getz Anne E. , Hwang Peter H. , Khanwalkar Ashoke , Kimple Adam J. , Lee Jivianne T. , Li Douglas A. , Norris Meghan , Nayak Jayakar V. , Owens Cameran , Patel Zara M. , Poch Katie , Schlosser Rodney J. , Smith Kristine A. , Smith Timothy L. , Soler Zachary M. , Suh Jeffrey D. , Turner Grant A. , Wang Marilene B. , Taylor‐Cousar Jennifer L. , Saavedra Milene T. , Beswick Daniel M. 
Published: February 2024

AbstractBackgroundChronic rhinosinusitis (CRS) is common in people with cystic fibrosis (PwCF). Rhinologic symptom prioritization and areas that influence CRS treatment choices, including pursuing endoscopic sinus surgery (ESS), remain understudied.MethodsAdult PwCF + CRS were enrolled at eight centers into a prospective, observational study (2019–2023). Participants were administered the 22‐SinoNasal Outcome Test (SNOT‐22) survey and a modified SNOT‐22 instrument examining symptom importance. We determined importance rankings for individual symptoms and SNOT‐22 symptom importance subdomains in two sets of subgroups—those pursuing ESS versus continuing medical management (CMT), and those on elexacaftor/tezacaftor/ivacaftor (ETI) versus not on ETI.ResultsAmong 69 participants, the highest priorities were nasal congestion (n = 48, 69.6% important), post‐nasal discharge (32, 46.4%), facial pain (29, 43.3%), waking up tired (27, 39.1%), and fatigue (26, 37.7%). Those electing surgery (n = 23) prioritized sleep and psychological dysfunction symptoms compared to those pursuing CMT (n = 49) (sleep median score = 19.0 [interquartile range: 12.0, 25.0] vs. 4.5 [0.0, 12.8]; p < 0.0001; psychological = 17.0 [7.0, 26.0] vs. 7.0 [0.0, 15.8]; p = 0.002). ETI users had comparable SNOT‐22 total symptom importance scores to non‐ETI users (p = 0.14). Non‐ETI users (n = 34) showed a trend toward prioritizing sleep symptoms compared to ETI users (n = 35) (13.0 [2.8, 22.3] vs. 6.0 [2.0, 17.0]; p = 0.055).ConclusionsNasal congestion and post‐nasal discharge were top priorities reported by PwCF + CRS. Those electing surgery prioritized sleep and psychological symptoms, highlighting their importance in pre‐operative discussions. Non‐ETI users’ prioritization of sleep improvement may highlight their unique disease impact and therapeutic needs; however, additional investigation is required.
Assessment of social vulnerability impact in care and prognosis of sinonasal cancers in the United States
Authors: Kanaris Achilles A. , Fei‐Zhang David J. , Fletcher Lily B. , Smith Stephanie S. , Patel Urjeet A. , D'Souza Jill N. , Chelius Daniel C. , Sheyn Anthony M. , Rastatter Jeffrey C. 
Published: February 2024

Key point
Social determinants of health interactively influence sinonasal cancer care and prognosis.
Housing‐transportation and socioeconomic status showed the largest associations with disparities.
The social vulnerability index can reveal the social determinants of sinonasal cancers.
Flexible Zn‐ion Electrochromic Batteries with Multiple‐color Variations
Authors: Liu Qinbo , Ou Xu , Niu Yajuan , Li Legeng , Xing Doudou , Zhou Yingjie , Yan Feng 
Published: February 2024

AbstractElectrochromic batteries as emerging smart energy devices are highly sought after owing to their real‐time energy monitoring through visual color conversion. However, their large‐scale applicability is hindered by insufficient capacity, inadequate cycling stability, and limited color variation. Herein, a flexible Zn‐ion electrochromic battery (ZIEB) was assembled with sodium vanadate (VONa+) cathode, ion‐redistributing hydrogel electrolyte, and Zn anode to address these challenges. The electrolyte contains anchored −SO3− and ‐NH3+, which facilitates ionic transportation and prevents Zn dendrite formation by promoting orientated Zn2+ deposition on the Zn (002) surface. The ZIEB exhibits a continuous reversible color transition, ranging from fully charged orange to mid‐charged brown and drained green. It also demonstrates a high specific capacity of 302.4 mAh ⋅ g−1 at 0.05 A ⋅ g−1 with a capacity retention of 96.3 % after 500 cycles at 3 A ⋅ g−1. Additionally, the ZIEB maintains stable energy output even under bending, rolling, knotting, and twisting. This work paves a new strategy for the design of smart energy devices in wearable electronics.
Synthesis and Reactivity of Ruthenium(BINAP)(PPh3)
Authors: Zhou Yifei , Wensink Niels H. , Pécharman Anne‐Frédérique , Miloserdov Fedor M. 
Published: February 2024

AbstractRu(BINAP)(PPh3)HCl cleanly reacts with LiCH2TMS to give Ru(BINAP)(PPh3) (1) that has been fully characterized, including by X‐ray diffraction (BINAP and TMS stand for (2,2′‐bis(diphenylphosphino)‐1,1′‐binaphthyl and trimethylsilyl respectively). In sharp contrast with other carbonyl‐free phosphine complexes of Ru(0), 1 demonstrates a strikingly high thermal stability and no propensity for intramolecular C−H activation (cyclometalation). Yet 1 coordinates acetonitrile and readily exchanges its PPh3 ligand with alkenes and dienes, thus behaving like a “masked” 16‐e Ru(0) species. Electron‐poor alkenes coordinate more readily than electron‐rich ones, which testifies for the nucleophilic character of the Ru(0)‐BINAP fragment. While being thermally stable, 1 is highly reactive and is capable of activating C−H and N−H bonds, and even of cleaving an inert N−Et bond. The combination of high reactivity and stability originates from the P,arene‐chelation by the BINAP ligand, i.e., the coordinated π‐arene stabilizes Ru(0) to prevent cyclometalation, yet it can slide upon substrate coordination, thereby enabling a variety of inert bond activation reactions to occur under mild conditions.
Amine‐releasable Mediator In situ Repair Perovskites for Efficient and Stable Perovskite Solar Cells
Authors: Zhao Ruonan , Tan Licheng , Luo Xiao , He Jiacheng , Dai Runying , Feng Chuizheng , Zhang Qingguo , Yang Jia , Chen Yiwang 
Published: February 2024

AbstractResidual lead iodide (PbI2) is deemed to a double‐edged sword in perovskite film as small amounts of PbI2 are beneficial to the photovoltaic performance, but excessive will cause degradation of photovoltaic performance and stability. Herein, an in situ repair strategy has been developed by introducing amine‐releasable mediator (methylammonium pyridine‐2‐carboxylic, MAPyA) to eliminate over‐residual PbI2 and regulate the crystal quality of perovskite film. Notably, MAPyA can be partially decomposed into methylamine (MA) gas and pyridine‐2‐carboxylic (PyA) during high temperature annealing. The released MA can locally form liquid intermediate phase, facilitating the reconstruction of perovskite microcrystals and residual PbI2. Moreover, the leftover PyA is confirmed to effectively passivate the uncoordinated lead ions in final perovskite film. Based upon this, superior perovskite film with optimized crystal structure and holistic negligible PbI2 is acquired. The assembled device realizes outstanding efficiency of 24.06 %, and exhibits a remarkable operational stability that maintaining 87 % of its origin efficiency after continuous illumination for 1480 h. And the unencapsulated MAPyA‐treated devices present significant uplift in humidity stability (maintaining ~93 % of the initial efficiency over 1500 h, 50–60 % relative humidity). Furthermore, the further optimization of this strategy with nanoimprint technology proves its superiority in the amplificative preparation for perovskite films.
Public support for carbon tax in South Korea: The role of tax design and revenue recycling
Authors: Kim Sung Eun , Kim Seung Yeob , Suh Junwoo 
Published: February 2024

AbstractCarbon tax is widely regarded as an effective and efficient method to reduce carbon emissions. However, the introduction of carbon tax has faced resistance from the public and interest groups. In this article, we examine the determinants of public support for carbon taxation in South Korea. While the expected cost of the carbon tax on individual citizens appears to be the most important determinant of preferences towards carbon tax, we also find that the public support changes depending on the design of the revenue recycling system. The public is more likely to support a carbon tax scheme that is earmarked to support the energy‐poor population compared to one that uses tax revenues for general government expenditures. The use of carbon tax revenues to create green sector jobs appears to significantly increase the support for carbon tax compared to the use of revenue for the general environment budget. Our findings suggest that while opposition towards carbon tax exists, certain design features such as universal carbon dividends can alleviate some resistance from the public.
Effect of inner diameter, filter length, and pore size on hollow fiber filter fouling during perfusion cell culture
Authors: WuDunn Dominique , Squeri Andrea , Vu Jimmy , Dhingra Ashna , Coffman Jon , Lee Ken 
Published: February 2024

AbstractAs the need for higher volumetric productivity in biomanufacturing grows, biopharmaceutical companies are increasingly investing in a perfusion cell culture process, most commonly one that uses a hollow fiber filter as the cell retention device. A current challenge with using hollow fiber filters is fouling of the membrane, which reduces product sieving and can increase transmembrane pressure (TMP) past process limitations. In this work, the impact of hollow fiber filter geometries on product sieving and hydraulic membrane resistance profiles is evaluated in a tangential flow filtration (TFF) perfusion system. The hollow fibers tested had lengths ranging from 19.8 to 41.5 cm, inner diameters (IDs) ranging from 1.0 to 2.6 mm, and pore sizes of 0.2 or 0.65 μm. The results showed that the shortest hollow fibers experienced higher product sieving while larger IDs contributed to both higher product sieving and lower hydraulic membrane resistances, illustrating the impact of filter geometry on process performance. The results also showed 0.2 μm pore size filters maintain higher product sieving, but also higher membrane resistances compared to 0.65 μm pore size filters. This study highlights the need for optimized hollow fiber filter geometries to maximize use of the membrane area, which in turn can reduce production costs and increase scalability of the perfusion process.
Feasible diet and circadian interventions reduce in vivo progression of FLT3‐ITD‐positive acute myeloid leukemia
Authors: Rodriguez Megan , Fekry Baharan , Murphy Brianna , Figueroa Mary , Cheng Tiewei , Raber Margaret , Wartenberg Lisa , Bell Donna , Triche Lisa , Crawford Karla , Ma Huaxian , Allton Kendra , Ahmed Ruwaida , Tran Jaime , Ranieri Christine , Konopleva Marina , Barton Michelle , Nunez Cesar , Eckel‐Mahan Kristin , Chandra Joya 
Published: February 2024

AbstractBackgroundAcute myeloid leukemia (AML) with an internal tandem duplication in the fms‐like tyrosine kinase receptor 3 gene (FLT3‐ITD) is associated with poor survival, and few studies have examined the impact of modifiable behaviors, such as nutrient quality and timing, in this subset of acute leukemia.MethodsThe influence of diet composition (low‐sucrose and/or low‐fat diets) and timing of diet were tested in tandem with anthracycline treatment in orthotopic xenograft mouse models. A pilot clinical study to test receptivity of pediatric leukemia patients to macronutrient matched foods was conducted. A role for the circadian protein, BMAL1 (brain and muscle ARNT‐like 1), in effects of diet timing was studied by overexpression in FLT3‐ITD‐bearing AML cells.ResultsReduced tumor burden in FLT3‐ITD AML‐bearing mice was observed with interventions utilizing low‐sucrose and/or low‐fat diets, or time‐restricted feeding (TRF) compared to mice fed normal chow ad libitum. In a tasting study, macronutrient matched low‐sucrose and low‐fat meals were offered to pediatric acute leukemia patients who largely reported liking the meals. Expression of the circadian protein, BMAL1, was heightened with TRF and the low‐sucrose diet. BMAL1 overexpression and treatment with a pharmacological inducer of BMAL1 was cytotoxic to FLT3‐ITD AML cells.ConclusionsMouse models for FLT3‐ITD AML show that diet composition and timing slows progression of FLT3‐ITD AML growth in vivo, potentially mediated by BMAL1. These interventions to enhance therapy efficacy show preliminary feasibility, as pediatric leukemia patients responded favorable to preparation of macronutrient matched meals.
Genetic variants in primary cilia‐related genes associated with the prognosis of first‐line chemotherapy in colorectal cancer
Authors: Qiu Lei , Chen Silu , Ben Shuai , Cui Jinxin , Lu Shan , Qu Rong , Lv Jinghuan , Shao Wei , Yu Qiang 
Published: February 2024

AbstractBackgroundPrimary cilia are antenna‐like organelles that conduct physical and chemical signals, which affect cell proliferation, migration, and differentiation. Some researchers have reported the correlation between primary cilia‐related genes and prognosis of colorectal cancer (CRC).MethodsThe association between single nucleotide polymorphisms (SNPs) of primary cilia‐related genes and outcome after the first‐line chemotherapy was explored by the Cox regression model. Expression qualitative trait locus (eQTL) analysis was performed to explore the impact of SNPs on gene expression. Tumor Immune Estimation Resource and TISIDB databases were used for investigating the relevance betweenODF2Land tumor infiltration immune cells and immunomodulators.ResultsWe identified that rs4288473 C allele ofODF2Lhad poor progression‐free survival (PFS) and overall survival (OS) of CRC patients in the additive model (adjusted HRPFS = 1.39, 95% CI = 1.14–1.70,p = 1.36 × 10−3, and adjusted HROS = 1.31, 95% CI = 1.03–1.65,p = 2.62 × 10−2). The stratified analysis indicated that rs4288573 CC/CT genotype was involved with poor prognosis in the irinotecan‐treated subgroup (PPFS = 1.03 × 10−2,POS = 3.29 × 10−3). Besides,ODF2LmRNA expression level was notably up‐regrated in CRC tissues. The C allele of rs4288573 was notably related to higherODF2LmRNA expression levels based on eQTL analysis. Functionally, knockdown ofODF2Linhibited cell proliferation and decrease the chemoresistance of HCT‐116 and DLD‐1 cells to irinotecan.ConclusionOur study indicates that rs4288573 inODF2Lis a potential predictor of the chemotherapy prognosis of CRC.
Warm autoimmune hemolytic anemia and hemophagocytic lymphohistiocytosis/macrophage activation syndrome occurring after COVID19 infection and administration of Casirivimab + Imdevimab (COVID19 monoclonal antibody)
Authors: Swartz Andrew W. , Novelli Enrico M. 
Published: February 2024

Key Clinical MessageWarm Autoimmune Hemolytic Anemia (WAHA) is the most common form of autoimmune hemolysis and there is a growing body of evidence of an association between SARS‐CoV‐2 infection, WAHA and a hyperinflammatory state, including hemophagocytic lymphohistiocytosis/macrophage activation syndrome. However, there is no literature to date of WAHA or hyperinflammatory state following administration of anti‐SARS‐CoV‐2 monoclonal antibody treatment. This report documents a case of a patient with history of WAHA who developed brisk hemolysis and a hyperinflammatory state consistent with hemophagocytic lymphohistiocytosis/macrophage activation syndrome after COVID‐19 infection and treatment with an anti‐SARS‐CoV‐2 monoclonal antibody. He was successfully treated with multimodal treatment involving steroids, intravenous immunoglobulins, rituximab, anakinra, and vincristine with resolution of the hemolysis.
Trifoliate gallbladder: A rare congenital anomaly masquerading as acute cholecystitis
Authors: Hussain Akbar , Inban Pugazhendi , Akuma Chinaza Mercy , Raj Rohan , Akuma Ogbonnaya , Nwoke Nnamdi Lionel , Kelechi Anasonye Emmanuel 
Published: February 2024

Key Clinical MessageTriple gallbladder, an extremely rare congenital anomaly, can mimic more common biliary conditions. Accurate diagnosis through imaging and a multidisciplinary approach is essential for timely surgical management, preventing complications, and ensuring better patient outcomes.AbstractThe multiplication of the gallbladder is a congenital malformation with a rare incidence of 1 in 4000 patients, among which the trifoliate gallbladder, even rarer, is included. Gallbladder anomalies are typically discovered incidentally while investigating conditions like gallstones, sedimentation, gallbladder inflammation, or malignancy. The clinical presentation of trifoliate gallbladder disease varies, and it may require a variety of imaging modalities to obtain a preoperative diagnosis. Recommended therapeutics for this anomaly are open or laparoscopic cholecystectomy, depending on the patient's condition. Early diagnosis of gallbladder multiplications is vital to improve prognosis and mitigate the risk of complications like cholelithiasis, cholecystitis, metaplasia, and adenocarcinoma. In our case, we present a 30‐year‐old male with the diagnosis of acute cholecystitis with triple gallbladder. A confirmatory diagnosis was made with magnetic resonance cholangiopancreatography (MRCP). The patient responded well to the therapy given and was discharged for follow‐up.
An unusual case of pleomorphic adenoma of the nasolacrimal duct
Authors: Zhang Katherynn , Mendez Adrian Ivar 
Published: February 2024

Key Clinical MessagePleomorphic adenoma is a common epithelial tumor but is unusual to involve the nasolacrimal duct and lacrimal sac. Current reported cases are sparse but may be helpful for delineating patterns of malignant transformation in the future.AbstractThis is a report of a 66‐year‐old patient with a pleomorphic adenoma involving the nasolacrimal duct and lacrimal sac, which is an unusual location for these tumors. To our knowledge, there are scarce publications in the current literature of similar cases.