bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental salinity modulates olfactory sensitivity in the euryhaline European seabass, Dicentrarchus labrax, acclimated to seawater and brackish water
Authors: Velez Zélia , Hubbard Peter C. , Alves Alexandra , Costa Rita A. , Guerreiro Pedro M. 
Published: January 2024

ABSTRACT
The olfactory epithelium of fish is – of necessity – in intimate contact with the surrounding water. In euryhaline fish, movement from seawater to freshwater (and vice versa) exposes the epithelium to massive changes in salinity and ionic concentrations. How does the olfactory system function in the face of such changes? The current study compared olfactory sensitivity in seawater- (35‰) and brackish water-adapted seabass (5‰) using extracellular multi-unit recording from the olfactory nerve. Seawater-adapted bass had higher olfactory sensitivity to amino acid odorants when delivered in seawater than in freshwater. Conversely, brackish water-adapted bass had largely similar sensitivities to the same odorants when delivered in seawater or freshwater, although sensitivity was still slightly higher in seawater. The olfactory system of seawater-adapted bass was sensitive to decreases in external [Ca2+], whereas brackish water-adapted bass responded to increases in [Ca2+]; both seawater- and brackish water-adapted bass responded to increases in external [Na+] but the sensitivity was markedly higher in brackish water-adapted bass. In seawater-adapted bass, olfactory sensitivity to l-alanine depended on external Ca2+ ions, but not Na+; brackish water-adapted bass did respond to l-alanine in the absence of Ca2+, albeit with lower sensitivity, whereas sensitivity was unaffected by removal of Na+ ions. A possible adaptation of the olfactory epithelium was the higher number of mucous cells in brackish water-adapted bass. The olfactory system of seabass is able to adapt to low salinities, but this is not immediate; further studies are needed to identify the processes involved.
Honey dressing for penile skin avulsion caused by traditional circumcision: a case report
Authors: Suryadinata Kevin Leonard , Song Agustini , Yovita Nabila Viera 
Published: January 2024

Objective: Penile skin avulsion is a rare complication of circumcision but commonly encountered as the result of traditional practice. We aimed to present the use of honey dressing and the benefit of its wound healing properties for management of such a complex wound. Case: A 24-year-old male patient with penile bleeding presented to the emergency department after undergoing traditional circumcision. Complete degloving of the penis with active bleeding and foul odour, along with heavy contamination of chewed betel leaves and powdered amoxicillin was found. Honey (Madu Nusantara, PT. Madu Nusantara, Indonesia) was used as dressing after copious irrigation using saline and povidone-iodine with bleeding control. Results: Honey dressing was shown to be effective for secondary wound healing of such a complicated and contaminated wound—in this case due to its antimicrobial, anti-inflammatory, immunostimulatory and autolytic debridement properties. A complete re-epithelialisation of the wound was achieved without progression to the hard-to-heal state by day 43. Suboptimal sexual function and aesthetic result due to wound contracture were observed as surgical reconstruction via split-thickness skin graft was refused due to cost. Conclusion: In this case report, honey dressing was shown to be effective for wound healing, even in a penile avulsion with complete skin loss and heavy contamination. In rural settings, where penile avulsion due to traditional circumcision is common, honey should be considered as one of the dressing choices.
Ultrasound blood flow characteristics changes in fetal umbilical artery thrombosis: A retrospective analysis
Authors: Hong Si-Jie , Hong Li-Wei , He Xiao-Qin , Zhong Xiao-Hong 
Published: January 2024

BACKGROUND
Umbilical artery thrombosis (UAT) is extremely uncommon and leads to adverse perinatal outcomes. Hypercoagulation of blood in pregnant women is suspected to be an important risk for UAT. Ultrasound is an effective way to detect thrombosis. The mother can monitor her own fetal health using ultrasound, which enables her to take preventative action in case of emergency.
AIM
To investigate ultrasonic blood signal after UAT in the umbilical artery, and evaluate the relationship between hypercoagulability and UAT.
METHODS
We described a case of a newly formed UAT with markedly altered ultrasonic indices of umbilical artery blood flow, and retrospectively studied it with 18 UAT patients confirmed by histopathology from October 2019 and March 2023 in Xiamen Women and Children's Hospital. Patients’ information was collected from medical archives, including maternal clinical data, neonatal outcomes, pathological findings and ultrasonic indices of umbilical artery blood flow, such as systolic-diastolic duration ratio (S/D), resistance index (RI), pulsatility index (PI) and peak systolic velocity (PSV). Ultrasound and coagulation indices were analyzed with matched samples t -test and Wilcoxon rank sum test using the statistical packages in R (version 4.2.1) including car (version 3.1-0) and stats (version 4.2.1), and visualized by ggplot2 package (version 3.3.6).
RESULTS
A patient with normal findings in second and third-trimester routine ultrasound scan developed UAT with severe changes in ultrasonic indices of umbilical artery blood flow (within 2.5th of reference ranges) in a short period of time. Statistical analysis of umbilical artery blood flow ultrasound indices for 19 patients with UAT showed that the decrease in S/D, RI, and PI and increase of PSV during the disease process was greater than that of non-UAT. All 18 patients delivered in our hospital showed characteristic manifestations of UAT on histological examination after delivery, most of which (16/18) showed umbilical cord abnormalities, with 15 umbilical cord torsion and 1 pseudoknot. Coagulation parameters were not significantly changed in UAT patients compared with normal pregnancy women.
CONCLUSION
Significant changes in ultrasound indicators after UAT were demonstrated. PSV can play important roles in the diagnosis of UAT. Hypercoagulability alone is not sufficient for the occurrence of UAT.
La Primera República a Barcelona als ulls d’un republicà finisecular
Authors: Pocino Àlex 
Published: January 2024

Ressenya de
Miquel González i Sugranyes, La República a Barcelona, 1873-1874,edició i estudi introductori de Jordi Roca Vernet i presentació de documentsi biografies de Ginés Puente, Barcelona, Ajuntament de Barcelona,2023, 429 p.
Decolonial Phenomenologies: The Languages and Affect of In-Betweenness in Gloria E. Anzaldúa and Josefina Báez’s Early Work
Authors: Lara Bonilla Inmaculada 
Published: January 2024

This article explores the intersections between Gloria Anzaldúa’s and Josefina Báez’s textual theories of in- betweenness, as they pertain to issues of textuality, and more broadly relationality, in their early work. In her life-long philosophical search Anzaldúa devised a phenomenology in which the metaphors of the border, borderlands, or bridges, and the concept of nepantla signal the place of writing in the context of coloniality, decoloniality, and migration. From her early thought, these concepts often capture not only issues of location, but also of intentionality and decolonial change. Similarly, Dominican American (DominicanYork) author, director, and performer Josefina Báez, explores the unstable spaces and temporariness of in-betweenness in the context of im/migration and colonization centering the experience of Dominican diasporic communities. Báez proposes concepts such as dominicanish or ‘bliss’ as imagined, relational spaces and states that are non-territorial, fleeting, and that resist the fixity of oppressive categorizations of the subject. Both authors are interested in finding the poetics that may be appropriate for such transfrontera spaces and states, as well as in theorizing new practices of reading (or viewing) and writing from these spaces. This paper describes these theories and shows how, by presenting readers with textual encounters in which the I must enter the unstable, hardly meltable, spaces in Borderlands/La Frontera: The New Mestiza (1987) and Dominicanish (2000), where the authors, as textual hosts, invite audiences to engage in a phenomenology of shifting where unsettling experiences of in-betweenness and impermanence may result in decolonial transformation.
Researching COVID to enhance recovery (RECOVER) tissue pathology study protocol: Rationale, objectives, and design
Authors: Troxel Andrea B. , Bind Marie-Abele C. , Flotte Thomas J. , Cordon-Cardo Carlos , Decker Lauren A. , Finn Aloke V. , Padera Robert F. , Reichard R. Ross , Stone James R. , Adolphi Natalie L. , Casimero Faye Victoria C. , Crary John F. , Elifritz Jamie , Faustin Arline , Ghosh Saikat Kumar B. , Krausert Amanda , Martinez-Lage Maria , Melamed Jonathan , Mitchell Roger A. , Sampson Barbara A. , Seifert Alan C. , Simsir Aylin , Adams Cheryle , Haasnoot Stephanie , Hafner Stephanie , Siciliano Michelle A. , Vallejos Brittany B. , Del Boccio Phoebe , Lamendola-Essel Michelle F. , Young Chloe E. , Kewlani Deepshikha , Akinbo Precious A. , Parent Brendan , Chung Alicia , Cato Teresa C. , Mudumbi Praveen C. , Esquenazi-Karonika Shari , Wood Marion J. , Chan James , Monteiro Jonathan , Shinnick Daniel J. , Thaweethai Tanayott , Nguyen Amber N. , Fitzgerald Megan L. , Perlowski Alice A. , Stiles Lauren E. , Paskett Moira L. , Katz Stuart D. , Foulkes Andrea S. ,   on behalf of the RECOVER Initiative Autopsy Group
Published: January 2024

Importance
SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or organ dysfunction after the acute phase of infection, termed Post-Acute Sequelae of SARS-CoV-2 (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are poorly understood. The objectives of the Researching COVID to Enhance Recovery (RECOVER) tissue pathology study (RECOVER-Pathology) are to: (1) characterize prevalence and types of organ injury/disease and pathology occurring with PASC; (2) characterize the association of pathologic findings with clinical and other characteristics; (3) define the pathophysiology and mechanisms of PASC, and possible mediation via viral persistence; and (4) establish a post-mortem tissue biobank and post-mortem brain imaging biorepository.

Methods
RECOVER-Pathology is a cross-sectional study of decedents dying at least 15 days following initial SARS-CoV-2 infection. Eligible decedents must meet WHO criteria for suspected, probable, or confirmed infection and must be aged 18 years or more at the time of death. Enrollment occurs at 7 sites in four U.S. states and Washington, DC. Comprehensive autopsies are conducted according to a standardized protocol within 24 hours of death; tissue samples are sent to the PASC Biorepository for later analyses. Data on clinical history are collected from the medical records and/or next of kin. The primary study outcomes include an array of pathologic features organized by organ system. Causal inference methods will be employed to investigate associations between risk factors and pathologic outcomes.

Discussion
RECOVER-Pathology is the largest autopsy study addressing PASC among US adults. Results of this study are intended to elucidate mechanisms of organ injury and disease and enhance our understanding of the pathophysiology of PASC.
Treating social cognition impairment with the online therapy ’SoCoBo’: A randomized controlled trial including traumatic brain injury patients
Authors: Lohaus Tobias , Reckelkamm Sally , Thoma Patrizia 
Published: January 2024

Objective
Acquired brain injuries (ABIs), such as traumatic brain injuries (TBIs), often entail impairments of general cognition (e.g., memory, attention or executive functions) and social cognition (e.g. emotion recognition, theory of mind [ToM], social problem-solving). The availability of fully computerized interventions targeting sociocognitive deficits specifically in neurologically impaired patients is extremely limited. Therefore, the Treatment Program for Deficits in Social Cognition and Social Competencies of the Ruhr University Bochum (SoCoBo), a fully computerized online therapy designed for ABI patients was evaluated in a randomized controlled trial involving TBI patients.

Method
Sixty-four patients with TBI were randomly assigned to two groups with 43 patients fully completing either SoCoBo (N = 27) or a commercially available computerized program for cognitive rehabilitation (RehaCom®, N = 16). All participants underwent comprehensive pre-post online neuropsychological assessment and worked with their respective rehabilitation programs for four days a week during a scheduled period of 12 weeks.

Results
After treatment, the SoCoBo group, but not the RehaCom® group showed significant improvements in facial emotion recognition and self-rated empathy. Moreover, in the SoCoBo group, an increase in empathy was also associated with increased life satisfaction after treatment. There were no improvements in ToM and social problem-solving. Furthermore, general cognition did not improve in any of the groups.

Conclusions
SoCoBo represents an effective new online therapy for the amelioration of deficits in key domains of social cognition. Its implementation in clinical practice will serve as a meaningful addition to the existing fully computerized approaches specifically in neurological patient groups.
The relationship of within-individual and between-individual variation in mental health with bodyweight: An exploratory longitudinal study
Authors: Mueller Julia , Ahern Amy L. , Jones Rebecca A. , Sharp Stephen J. , Davies Alan , Zuckerman Arabella , Perry Benjamin I. , Khandaker Golam M. , Rolfe Emanuella De Lucia , Wareham Nick J. , Rennie Kirsten L. 
Published: January 2024

Background
Poor mental health is associated with obesity, but existing studies are either cross-sectional or have long time periods between measurements of mental health and weight. It is, therefore, unclear how small fluctuations in mental wellbeing within individuals predict bodyweight over short time periods, e.g. within the next month. Studying this could identify modifiable determinants of weight changes and highlight opportunities for early intervention.

Methods
2,133 UK adults from a population-based cohort completed monthly mental health and weight measurements using a mobile app over a period of 6–9 months. We used random intercept regression models to examine longitudinal associations of depressive symptoms, anxiety symptoms and stress with subsequent weight. In sub-group analyses, we included interaction terms of mental health variables with baseline characteristics. Mental health variables were split into “between-individual” measurements (= the participant’s median score across all timepoints) and “within-individual” measurements (at each timepoint, the difference between the participant’s current score and their median).

Results
Within-individual variation in depressive symptoms predicted subsequent weight (0.045kg per unit of depressive symptom severity, 95% CI 0.021–0.069). We found evidence of a moderation effect of baseline BMI on the association between within-individual fluctuation in depressive symptoms and subsequent weight: The association was only apparent in those with overweight/obesity, and it was stronger in those with obesity than those with overweight (BMI<25kg/m2: 0.011kg per unit of depressive symptom severity [95% CI -0.017 to 0.039]; BMI 25–29.9kg/m2: 0.052kg per unit of depressive symptom severity [95%CI 0.010–0.094kg]; BMI≥30kg/m2: 0.071kg per unit of depressive symptom severity [95%CI 0.013–0.129kg]). We found no evidence for other interactions, associations of stress and anxiety with weight, or for a reverse direction of association.

Conclusion
In this exploratory study, individuals with overweight or obesity were more vulnerable to weight gain following higher-than-usual (for that individual) depressive symptoms than individuals with a BMI<25kg/m2.
Hubungan Kemampuan Adaptasi Kerja dengan Penerapan Kesehatan dan Keselamatan Kerja Perawat
Authors: Astawa I Made Adi , Wati Ni Made Nopita , Wati Ketut Lisna 
Published: January 2024

The Hospital occupational health and safety programs’ objectives to guarantee and protecting the nurses’ health and safety. However, nurses need to adapt regarding the working conditions to implement the nursing service optimally. This study aims to identify the relationship between the nurses' working adaptability and the implementation of occupational health and safety among associate nurses. This study was a quantitative study employed a cross-sectional design. The sampling technique employed in this study was purposive sampling with a sample size of 103 associate nurses choosen by using inclusion and exclusion criteria. The instruments employed to measure adaptability and application of occupational health and safety was questionnaires that has been tested for validity and reliability. This study has been ethically approved through ethical clearance number 070/5630/RSUDW. The data analyzed employed in this study was Rank Spearman Correlation test. The study results found that the majority of nurses showed have a good working adaptability (86 peoples;83,5%), the occupational health and safety implementation (88 peoples, 85,4%) by p-value = 0.000; r = 0.780 which means there is a significant relationship between the nurses' working adaptability and the implementation of occupational health and safety with a strong positive relationship. Nurses are expected to implement occupational health and safety optimally in order to improve the quality of nursing care services delivered to patients.
Neurodevelopmental outcomes in two cases of artemis deficiency
Authors: Hu Angela , Almatrafi Omar , Kim Vy HD , Wall Donna , Brager Rae 
Published: January 2024

Background: Severe Combined Immunodeficiency (SCID) is a category of inborn errors of immunity where there is impaired T and B cell development and/or function. Artemis SCID (Art-SCID) is characterized by dysfunctional Artemis protein, which is crucial for V(D)J recombination in T and B cell maturation. Art-SCID is fatal without management, and current definitive treatment involves hematopoietic stem cell transplantation (HSCT) or gene therapy. As the prognosis and survival of SCID patients improves, current research has begun unveiling long-term complications and morbidities. Previous literature has reported neurodevelopmental abnormalities in SCID patients, such as developmental delay and Autism Spectrum Disorder (ASD). However, it remains unknown whether these neurodevelopmental differences are linked to the SCID mutation, an adverse outcome of treatment and hospitalization, or comorbid social isolation and psychosocial challenges. Aims: In this case series, we discuss two cases of Art-SCID which presented with neurodevelopmental deficits following successful HSCT. Results: In both cases, SCID was detected on Newborn Screening (NBS), and Art-SCID was confirmed with genetic testing. Both patients were successfully treated with HSCT at 80 days of life, and followed up clinically well, with robust cell counts. Both patients later presented in toddlerhood with developmental, speech and language delay, however only one patient met diagnostic criteria for ASD. Conclusion: The definitive relationship between SCID, HSCT, and neurodevelopmental outcomes remain unclear, and warrants further study to allow for early intervention. We are currently working with colleagues across the country to further investigate and define this complex relationship. Statement of Novelty: We are investigating the complex relationship between SCID, HSCT, and potential neurodevelopmental outcomes. We present two cases of patients with Artemis SCID who were successfully treated with HSCT, and later presented in toddlerhood with developmental, speech, and language delay.
Hypoxic peripheral chemoreflex stimulation‐dependent cardiorespiratory coupling is decreased in swimmer athletes
Authors: Andrade David C. , Arce‐Álvarez Alexis , Salazar‐Ardiles Camila , Toledo Camilo , Guerrero‐Henriquez Juan , Alvarez Cristian , Vasquez‐Muñoz Manuel , Izquierdo Mikel , Millet Gregoire P. 
Published: January 2024

AbstractSwimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory coupling due to their decreased hypoxic peripheral response. To resolve this hypothesis, we conducted a study using coherence time‐varying analysis to assess the cardiorespiratory coupling in swimmer athletes. We recruited 12 trained swimmers and 12 control subjects for our research. We employed wavelet time‐varying spectral coherence analysis to examine the relationship between the respiratory frequency (Rf) and the heart rate (HR) time series during normoxia and acute chemoreflex activation induced by five consecutive inhalations of 100% N2. Comparing swimmers to control subjects, we observed a significant reduction in the hypoxic ventilatory responses to N2 in swimmers (0.012 ± 0.001 vs. 0.015 ± 0.001 ΔVE/ΔVO2, and 0.365 ± 0.266 vs. 1.430 ± 0.961 ΔVE/ΔVCO2/ΔSpO2, both p < 0.001, swimmers vs. control, respectively). Furthermore, the coherence at the LF cutoff during hypoxia was significantly lower in swimmers compared to control subjects (20.118 ± 3.502 vs. 24.935 ± 3.832 area under curve [AUC], p < 0.012, respectively). Our findings strongly indicate that due to their diminished chemoreflex control, swimmers exhibited a substantial decrease in cardiorespiratory coupling during hypoxic stimulation.
Mechanism study on improving aroma quality of pineapple wine by branched-chain amino acids addition
Authors: Peng Mengdi , Wang Huacheng , Yang Shaojie , Wu Dianhui , Yang Hua , Lu Jian 
Published: January 2024

Abstract
The metabolic mechanism of branched-chain amino acids of yeast and the effect of addition of branched-chain amino acids on aroma quality of pineapple wine were investigated. The results showed that adding 400 mg L−1 leucine, isoleucine and valine could increase adenosine triphosphate content, aminotransferase activity and total aroma compounds content of yeast by 80.30 %, 39.94 % and 100.67 % at most, respectively. The total aroma compounds content of pineapple wine fermented with the addition of 400 mg L−1 leucine, 400 mg L−1 isoleucine and 800 mg L−1 valine was increased by 53.80 %, 27.62 %, and 10.70 %, respectively. These results indicated that branched-chain amino acids could promote the growth of yeast to accumulate more adenosine triphosphate content and increased the activity of aminotransferases, thus promoting the entry of amino acids into the Ehrlich pathway to participate in the synthesis of higher alcohols and esters, and improving the aroma and overall quality of pineapple wine.
Uniqueness of meromorphic functions and their powers in set sharing
Authors: BE Manjunath , Waghamore Harina P. 
Published: January 2024

Abstract
The objective of this study is to determine whether the existence of shared sets S containing both meromorphic (entire) functions and their higher derivatives, as well as powers of meromorphic functions and their differential polynomials, could result in uniqueness. The main focus is on determining the precise solutions to various differential equations. This problem is being studied in a broader context, specifically in set sharing.