bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symmetry and monotonicity property of a solution of $(p,q)$ Laplacian equation with singular terms
Authors: Jana Ritabrata 
Published: February 2024

This paper examines the behavior of a positive solution

u\in C^{1,\alpha}(\overline{B_R(x_0)})

of the

(p,q)

Laplace equation with a singular term and zero Dirichlet boundary condition. Specifically, we consider the equation

\left\{ \begin{aligned}-\operatorname{div}(\lvert\nabla u\rvert^{p-2}\nabla u+ a(x) \lvert\nabla u\rvert^{q-2}\nabla u)&= \frac{g(x)}{u^\delta}+h(x)f(u)&&\text{in}\ B_{R}(x_{0}),\\ u&= 0&&\text{on}\ \partial B_{R}(x_{0}).\end{aligned} \right.

We assume that

0<\delta<1

,

1<p\leq q<\infty

, and

f

is a

C^{1}(\mathbb{R})

nondecreasing function. Our analysis uses the moving plane method to investigate the symmetry and monotonicity properties of

u

. Additionally, we establish a strong comparison principle for solutions of the

(p,q)

Laplace equation with radial symmetry under the assumptions that

1<p\leq q\leq 2

and

f\equiv1

.
Systemic Inflammation Response Index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial
Authors: Pacheco-Barcia Vilma , Custodio-Cabello Sara , Carrasco-Valero Fatima , Palka-Kotlowska Magda , Mariño-Mendez Axel , Carmona-Bayonas Alberto , Gallego Javier , Martín A J Muñoz , Jimenez-Fonseca Paula , Cabezon-Gutierrez Luis 
Published: February 2024

BACKGROUND
The prognostic value of the Systemic Inflammation Response Index (SIRI) in advanced pancreatic cancer is recognized, but its correlation with patients´ nutritional status and outcomes remains unexplored.
AIM
To study the prognostic significance of SIRI and weight loss in metastatic pancreatic cancer.
METHODS
The PANTHEIA-Spanish Society of Medical Oncology (SEOM) study is a multicentric (16 Spanish hospitals), observational, longitudinal, non-interventional initiative, promoted by the SEOM Real World-Evidence work group. This pilot study sought to analyze the association between weight loss and inflammatory status as defined by SIRI. The cohort stems from a proof-of-concept pilot study conducted at one of the coordinating centers. Patients with pathologically confirmed metastatic pancreatic adenocarcinoma, treated from January 2020 to January 2023, were included. The index was calculated using the product of neutrophil and monocyte counts, divided by lymphocyte counts, obtained within 15 days before initiation chemotherapy. This study evaluated associations between overall survival (OS), SIRI and weight loss.
RESULTS
A total of 50 patients were included. 66% of these patients were male and the median age was 66 years. Metastasis sites: 36% liver, 12% peritoneal carcinomatosis, 10% lung, and 42% multiple locations. Regarding the first line palliative chemotherapy treatments: 50% received gemcitabine plus nab-paclitaxel; 28%, modified fluorouracil, leucovorin, irinotecan and oxaliplatin, and 16% were administered gemcitabine. 42% had a weight loss > 5% in the three months (mo) preceding diagnosis. 21 patients with a SIRI ≥ 2.3 × 103/L exhibited a trend towards a lower median OS compared to those with a SIRI < 2.3 × 103/L (4 vs 18 mo; P < 0.000). Among 21 patients with > 5% weight loss before diagnosis, the median OS was 6 mo, in contrast to 19 mo for those who did not experience such weight loss (P = 0.003). Patients with a weight loss > 5% showed higher SIRI levels. This difference was statistically significant (P < 0.000). For patients with a SIRI < 2.3 × 103/L, those who did not lose > 5% of their weight had an OS of 20 mo, compared to 11 mo for those who did (P < 0.001). No association was found between carbohydrate antigen 19-9 levels ≥ 1000 U/mL and weight loss.
CONCLUSION
A higher SIRI was correlated with decreased survival rates in patients with metastatic pancreatic cancer and associated with weight loss. An elevated SIRI is suggested as a predictor of survival, emphasizing the need for prospective validation in the upcoming PANTHEIA-SEOM study.
Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer
Authors: Lu You-Wang , Ding Zhao-Li , Mao Rui , Zhao Gui-Gang , He Yu-Qi , Li Xiao-Lu , Liu Jiang 
Published: February 2024

BACKGROUND
Aberrant methylation is common during the initiation and progression of colorectal cancer (CRC), and detecting these changes that occur during early adenoma (ADE) formation and CRC progression has clinical value.
AIM
To identify potential DNA methylation markers specific to ADE and CRC.
METHODS
Here, we performed SeqCap targeted bisulfite sequencing and RNA-seq analysis of colorectal ADE and CRC samples to profile the epigenomic-transcriptomic landscape.
RESULTS
Comparing 22 CRC and 25 ADE samples, global methylation was higher in the former, but both showed similar methylation patterns regarding differentially methylated gene positions, chromatin signatures, and repeated elements. High-grade CRC tended to exhibit elevated methylation levels in gene promoter regions compared to those in low-grade CRC. Combined with RNA-seq gene expression data, we identified 14 methylation-regulated differentially expressed genes, of which only AGTR1 and NECAB1 methylation had prognostic significance.
CONCLUSION
Our results suggest that genome-wide alterations in DNA methylation occur during the early stages of CRC and demonstrate the methylation signatures associated with colorectal ADEs and CRC, suggesting prognostic biomarkers for CRC.
Study of Release Time 25 NM Runway 34 At Airnav Palangka Raya Branch
Authors: Pasa Inda Tri , Tommy Hutabarat Liber , Restiana Rizny , Ramadhini Fadril Deby 
Published: February 2024

Bandar Udara Tjilik Riwut memberikan pelayanan lalu lintas penerbangan yaitu Aerodrome Control Tower (ADC) dan Approach Control Procedure (APP). Bandara ini merupakan salah satu bandara penghubung untuk bandara perintis yang ada disekitarnya. Dalam memberikan pelayanan, pendekatan utama yang digunakan untuk runway 34 adalah Instrument Landing System (ILS) dan straight in approach. Selama melaksanakan observasi di Airnav Cabang Palangka Raya, ditemukan sebuah permasalahan yang menimbulkan pendapat berbeda-beda antara ATC yaitu belum adanya pengkajian ulang terkait standar separasi yang tersedia dalam SOP akibat dari adanya penambahan apron baru. Berdasarkan Standar Operasional Prosedur (SOP) Palangka Raya disebutkan bahwa pesawat udara yang akan berangkat dapat dijzinkan masuk landasan saat pesawat udara yang akan mendarat berjarak minimal 25 NM dari Threshold RWY, namun jarak tersebut dihitung dari north apron yang merupakan apron lama dari Bandar Udara Tjilik Riwut menuju RWY 34 sedangkan saat ini Bandar Udara Tjilik Riwut terdapat penambahan apron baru yaitu south apron sehingga perlu adanya pengkajian ulang apakah jarak 25 NM bisa dijadikan sebagai acuan juga untuk memasukkan pesawat ke landasan apabila pesawat line up dari south apron. Dalam melaksanakan observasi, penulis mengumpulkan data pergerakan pesawat yang akan berangkat dan yang akan mendarat menggunakan runway 34. Dari observasi yang telah dilakukan dapat disimpulkan bahwa jarak 25 Nm masih layak untuk digunakan sebagai standar untuk memasukkan pesawat ke landasan. Dengan adanya penambahan apron tentu harus ada pengkajian ulang dalam Standar Operasional Prosedur (SOP). Kajian inilah yang diharapkan dapat membantu Airnav Cabang Palangka Raya dalam menentukan standar separasi untuk mengizinkan pesawat masuk landasan dan dengan adanya standar separasi tersebut, diharapkan para ATC dapat mewujudkan pelayanan lalu lintas yang aman dan efektif.
Suporte social para acolhimento de irmãos de prematuros em UTI neonatal:"caderninho de histórias para colorir e brincar" / Social support for siblings of premature infants in nicu: the “notebook of stories to color and play”
Authors: Ruas Teresa Cristina Brito , Gagliardo Heloisa GRG , Françozo Maria de Fátima de Campos , Mello Bernadete Balanin Almeida , De Freitas Márcia , Albuquerque Raquel Costa 
Published: February 2024

O nascimento de um bebê prematuro e sua internação trazem mudanças na rotina familiar e sofrimento para os irmãos. Práticas humanizadas em UTIN promovem ações focadas no núcleo familiar e acolhimento. Esta proposta apresenta material lúdico de suporte social para acolhimento dos irmãos de prematuros. Propomos um “Caderninho de Histórias”, para que os irmãos compreendam o ambiente neonatal, as necessidades do bebê e elaborem sentimentos decorrentes da ausência dos pais. Esperamos que esse material fortaleça vínculos afetivos familiares para que sejam continuados após alta hospitalar. AbstractThe birth of premature babies and their hospitalization changes family routine and causes suffering for siblings. The humanization in NICUs is focused on the family nucleus and on holding them. We present ludic material as a means of supporting siblings coping with the new situation. A “Notebook of Stories” for siblings was devised to help them understand the neonatal environment, the baby's needs, and to help them elaborate feelings arising from the absence of the parents. We expect this material to strengthen family bounds which may last after hospital discharge.Keywords: Infant Premature, Holding, Social Support, Sibling Relations, Humanization of Assistance.ResumenEl nacimiento de un bebé prematuro y su hospitalización traen cambios en la rutina familiar y el sufrimiento de los hermanos. Las prácticas humanizadas en la UCIN promueven acciones enfocadas en el núcleo familiar y la recepción. Esta propuesta presenta material lúdico de apoyo social para dar la bienvenida a los hermanos de bebés prematuros. Proponemos un "Cuaderno de historias", para que los hermanos entiendan el entorno neonatal, las necesidades del bebé y los sentimientos elaborados que resultan de la ausencia de los padres. Esperamos que este material fortalezca los lazos afectivos familiares para que puedan continuar después de alta hospitalaria.Palabras clave: Recien Nacido Prematuro, Acogimiento, Apoyo Social, Relaciones entre Hermanos, Humanización de la Atención.
Implications of the Role of Tourism Carrying Capacity in the Development of Sustainable Tourism Destinations
Authors: Haribudiman Irwan , Berliandaldo Mahardhika , Holman Fasa Angga Wijaya 
Published: February 2024

Tourism contributes to increasing global and national Gross Domestic Product (GDP) growth. However, there are also negative impacts on tourism activities. One of the implementations to minimize negative impacts can be carried out by applying the carrying capacity of the destination (tourism carrying capacity/TCC). This study aims to determine the implications of the role of tourism carrying capacity in sustainable tourism development, which focuses on the causality relationship between tourism destination governance policies and tourism carrying capacity (TCC). This study uses a qualitative library/desk study method with a Driving Forces, Pressures, State, Impacts, and Responses (DPSIR) framework analysis approach. The five dimensions of the carrying capacity of tourism destinations used in the DPSIR framework are territorial, governance, economic, social, and environmental. As a result, three framework findings and strategic analysis implications were obtained. First, it required the restoration of natural resources, environment, and ecosystems; second, carrying out integrated planning in land use, economic growth, strengthening socio-demographics, and a sustainable environment; third, educating tourists to transform the attitude, behavior, and ethics of tourists. The overall strategic analysis framework aligns with various tourism development programs to maintain natural, economic, social, and environmental balances that apply sustainable tourism by implementing stakeholder cooperation.
Unveiling Impact of Electron Beam Optics on Weld Attributes in EN30B Steel
Authors: Singh Vasundhara , Roy Gour Gopal , Srirangam Prakash 
Published: February 2024

The influence of electron optics in terms of beam oscillation (BO) has been studied on weld quality of several steels and reported to develop cosmetic weld with smooth surface and enhanced weld properties. However, effect of electron BO on the weld quality of medium carbon low alloy steel, especially EN30B, has not reported well and investigated in this study. By manipulating magnetic lens in-line with electron beam, the diameter of oscillating beam (OD) and its effect on weld quality has been studied. The OD was changed between 0.5 mm and 2 mm. Numerous tests, including X-ray diffraction, scanning electron microscopy (SEM), Electron Backscattered Diffraction (EBSD), hardness, wear, and tensile, were used to characterize the weld quality. Welds with BO significantly lowered the heat input rate than welds without oscillation. In presence of BO, retained austenite (RA) in the weld increased and it became least in welds made without BO. Tensile residual stress was found in the fusion zone (FZ) and it was higher with BO, especially with higher OD. In contrast to columnar grains predominantly found in welds made without BO, significant equiaxed grains were identified in welds made with BO. Nonmetallic inclusions (NMIs) in the weld became finer and less by use of BO. Introducing BO enhanced the hardness and reduced wear rate of weld, particularly at greater beam OD. Although weld strength was diminished in comparison to the base metal (BM), BO increased the weld's ductility and strength.

Received: 26 October 2023 | Revised: 15 January 2024 | Accepted: 18 January 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
Seehofers Erbe
Authors: Vetter Bernhard 
Published: February 2024

Frankfurt a.M. Die Windkraftwerke in der Nordsee haben im vergangenen Jahr weniger Strom geliefert. Grund sind Abregelungen wegen Engpässen im Stromnetz. So zahlen alle Stromverbraucher für die Folgen bayerischer Politik.
PENGARUH KONFLIK DAN LINGKUNGAN KERJA TERHADAP EFEKTIVITAS KERJA PEGAWAI PADA DINAS PENDIDIKAN DAN KEBUDAYAAN KABUPATEN MUSI BANYUASIN
Authors: . Heriyana , Alamsyah Rully , Erlina Neti 
Published: February 2024

ABSTRAK
Tujuan penelitian yang dilakukan adalah untuk mengetahui pengaruh konflik dan lingkungan kerja secara simultan terhadap efektivitas kerja pegawai pada kantor Dinas Pendidikan dan Kebudayaan Kabupaten Musi Banyuasin. Metode penelitian yang digunakan adalah metode deskriptif kuantitatif. Teknik pengumpulan data yang digunakan adalah penelitian kuesioner, observasi dan studi dokumentasi. Analisis data dilakukan menggunakan uji validitas, uji reliabilitas, uji asumsi klasik, regresi linier berganda, koefisien korelasi dan uji hipotesis (uji t dan uji F). Berdasarkan hasil pengujian hipotesis secara parsial variabel konflik (X1) menunjukkan nilai t hitung> t tabel (2,717> t tabel 1,983), maka Ho ditolak, artinya secara parsial ada pengaruh signifikan antara konflik terhadap efektivitas kerja, Jadi dari kasus ini dapat disimpulkan bahwa secara parsial terdapat pengaruh antara konflik terhadap efektivitas kerja pegawai pada kantor Dinas Pendidikan dan Kebudayaan Kabupaten Musi Banyuasin. Sedangkan hasil pengujian hipotesis variabel lingkungan kerja (X2) menunjukkan nilai t hitung> t tabel (2,463> t tabel 1,983), m
aka H0 ditolak, artinya secara parsial ada pengaruh signifikan lingkungan kerja terhadap efektivitas kerja. Jadi dari kasus ini dapat disimpulkan bahwa secara parsial ada pengaruh lingkungan kerja terhadap efektivitas kerja pegawai pada kantor Dinas Pendidikan dan Kebudayaan Kabupaten Musi Banyuasin. Kata Kunci : Konflik, Lingkungan Kerja, Efektivitas kerja
PENGARUH KEADILAN ORGANISASI TERHADAP INTENSI KELUAR PADA KARYAWAN DENGAN KEPUASAN KERJA SEBAGAI VARIABEL MEDIASI PADA PT. NUSANTARA CARD SEMESTA KOTA MEDAN
Authors: Laia Welisa , Lase Herlina , Elanda Yonci 
Published: February 2024

ABSTRAK
Tujuan dari penelitian ini adalah untuk menjelaskan: a) pengaruh keadilan organisasional terhadap niat keluar karyawan di PT Nusantara Card Semesta Kota Medan; b) pengaruh keadilan organisasional terhadap tingkat kepuasan kerja karyawan di PT Nusantara Card Semesta Kota Medan; c) pengaruh antara tingkat kepuasan kerja karyawan dan niat keluar karyawan di PT Nusantara Card Semesta Kota Medan; dan d) pengaruh keadilan organisasional terhadap keinginan karyawan untuk meninggalkan perusahaan. Hasil penelitian menunjukkan bahwa keinginan karyawan untuk keluar secara signifikan dipengaruhi oleh keadilan organisasional, yang diperkuat oleh pernyataan thitung > ttabel (5,845 > 1,679). Hasil ini menunjukkan bahwa keadilan organisasional memiliki pengaruh sekitar 19,080% terhadap kepuasan kerja dan pengaruh sekitar 58,45% terhadap intensi keluar karyawan. Faktor keadilan organisasional memiliki dampak signifikan terhadap tingkat kepuasan kerja, yang dibuktikan dengan nilai thitung > ttabel (13,444 > 1,679). Dari grafik tersebut, terlihat bahwa tingkat kepuasan kerja dipengaruhi oleh keadilan organisasional sekitar 13,4%, sementara intensi keluar karyawan dipengaruhi oleh tingkat kepuasan kerja (thitung 4,689 > 1,679). Hasil pengujian menunjukkan bahwa di PT Nusantara Card Semesta Kota Medan, kepuasan kerja memiliki pengaruh sekitar 46,89% terhadap intensi keluar karyawan, keadilan organisasi memiliki pengaruh sekitar 79,6%, dan sisanya sekitar 20,4% dijelaskan diluar penelitian ini.
Kata Kunci: Keadilan Organisasi, Intensi Keluar, Kepuasan Kerja, Mediasi
Non-destructive multi-sensor core logging allows for rapid imaging and estimation of frozen bulk density and volumetric ice content in permafrost cores
Authors: Pumple Joel , Monteath Alistair , Harvey Jordan , Roustaei Mahya , Alvarez Alejandro , Buchanan Casey , Froese Duane 
Published: February 2024

Abstract. Permafrost cores provide physical samples that can be used to measure the characteristics of frozen ground. Measurements of core physical properties, however, are typically destructive and time intensive. In this study, multi-sensor core logging (MSCL) is used to provide a rapid (∼2–3 cm core depth per minute), high-resolution, non-destructive method to image and collect the physical properties of permafrost cores, allowing for the visualization of cryostructures and estimation of frozen bulk density, magnetic susceptibility, and volumetric ice content. Six permafrost cores with differing properties were analyzed using MSCL and compared with established destructive analyses to assess the potential of this instrument both in terms of accuracy and relative rate of data acquisition. A calibration procedure is presented for gamma ray attenuation from a 137Cs source that is specific to frozen-core materials. This accurately estimates frozen bulk density over the wide range of material densities found in permafrost. MSCL frozen bulk density data show agreement with destructive analyses based on discrete-sample measurements, with an RMSE of 0.067 g cm−3. Frozen bulk density data from the gamma attenuation, along with soil dry bulk density measurements for different sediment types, are used to estimate volumetric ice content. This approach does require an estimation of the soil dry bulk density and assumption of air content. However, the averaged results for this method show good agreement with an RMSE of 6.7 %, illustrating MSCL can provide non-destructive estimates of volumetric ice contents and a digital archive of permafrost cores for future applications.
MOLDED ACTIVATED CARBON BASED ON A SYNTHETIC BINDER OBTAINED BY TREATING TAR WITH SULFURIC ACID
Authors: Кугатов П.В. , Ивашкина Е.А. , Жирнов Б.С. 
Published: February 2024

В работе предложен способ получения углеродного адсорбента в виде экструдатов на основе гудрона и различных углеродных наполнителей. Для получения гранул сорбента навеску гудрона растворяли в избытке гептана, при непрерывном перемешивании раствора добавляли наполнитель, далее концентрированную серную кислоту. После образования связующего материала из гудрона отделяли твердый продукт; из образовавшейся пасты экструдировали «зеленые» гранулы, которые подвергали карбонизации и последующей активации водяным паром. Определены соотношения, позволяющие получать углеродные гранулы с наилучшими показателями поверхности (до 900 м2/г) и механической прочности: массовое соотношение гудрон/наполнитель 0,5:1, кислота/гудрон – 1:1. При использовании двух различных наполнителей (скорлупа грецкого ореха и кокс на основе гудрона) показано различие формирования микро-, мезопористой структуры углеродных гранул после активации: образцы на основе кокса дают более однородную микропористую структуру с меньшим содержанием мезопор. Благодаря возможности строго контролировать параметры процесса на стадии формования (свойства гудрона, соотношение компонентов) данная методика позволяет получать углеродные гранулы со стабильными характеристиками (удельная поверхность, механическая прочность).
The paper proposes a method for obtaining a carbon adsorbent in the form of extrudates based on bitumen and various carbon fillers: the bitumen suspension was dissolved in excess of heptane, with continuous mixing of the solution, filler was added, then concentrated sulfuric acid, after the formation of a binder, the resulting solid product was separated; «green» granules were extruded from the resulting paste, which were subjected to carbonization and subsequent activation by steam. The ratios allowing to obtain carbon granules with the best surface indicators (up to 900 m2/g) and mechanical strength are determined: the mass ratio of bitumen/filler is 0.5 to 1, acid/bitumen is 1 to 1. When using two different fillers (walnut shell and bitumen-based coke), the difference in the formation of the micro/meso porous structure of carbon granules after activation is shown: coke-based samples give a more homogeneous microporous structure with a lower content of mesopores. Due to the ability to strictly control the process parameters at the molding stage (properties of bitumen, the ratio of components), this technique allows you to obtain carbon granules with a stable set of characteristics (specific surface area, mechanical strength).
DNI Forecast Tool for the Smart Operation of a Parabolic Trough Collector System With Concrete Thermal Energy Storage
Authors: Sattler Johannes Christoph , Atti Vikrama , Alexopoulos Spiros , Teixeira Boura Cristiano , Herrmann Ulf , Dutta Siddharth , Kioutsioukis Ioannis 
Published: February 2024

This work presents a basic forecast tool for predicting direct normal irradiance (DNI) in hourly resolution, which the Solar-Institut Jülich (SIJ) is developing within a research project. The DNI forecast data shall be used for a parabolic trough collector (PTC) system with a concrete thermal energy storage (C-TES) located at the company KEAN Soft Drinks Ltd in Limassol, Cyprus. On a daily basis, 24-hour DNI prediction data in hourly resolution shall be automatically produced using free or very low-cost weather forecast data as input. The purpose of the DNI forecast tool is to automatically transfer the DNI forecast data on a daily basis to a main control unit (MCU). The MCU automatically makes a smart decision on the operation mode of the PTC system such as steam production mode and/or C-TES charging mode. The DNI forecast tool was evaluated using historical data of measured DNI from an on-site weather station, which was compared to the DNI forecast data. The DNI forecast tool was tested using data from 56 days between January and March 2022, which included days with a strong variation in DNI due to cloud passages. For the evaluation of the DNI forecast reliability, three categories were created and the forecast data was sorted accordingly. The result was that the DNI forecast tool has a reliability of 71.4 % based on the tested days. The result fulfils SIJ’s aim to achieve a reliability of around 70 %, but SIJ aims to still improve the DNI forecast quality.