bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilisation of Information and Communication Technology in Teaching and Assessment of Secondary School Students in Tanzania
Authors: Swai Saukwaeli E. 
Published: January 2024

This study assessed the implementation of ICT as a pedagogical tool in teaching and assessment of secondary school students in Tanzania. The study employed a survey design with 179 secondary school science teachers. One teacher was randomly sampled from each of 179 randomly selected secondary schools. The teachers responded to questionnaires. Responses from questionnaires were coded and numbers entered into M-Excel for processing. Results obtained were presented in Tables showing absolute numbers and percentages. The study established that 62 per cent of teachers were trained in ICT as a pedagogical tool. They used the knowledge in teaching and assessment aspects such as searching teaching materials through internet (90%), examination word-processing (81%), typing notes (80%), processing examination results (59%) and using projectors in classroom instruction (56%). However, no teacher was found to use computer technology for assessment. Teachers faced various challenges in utilisation of ICT such as inadequate number of ICT equipment (78%), inadequate knowledge and skills in ICT (59%), unreliable internet (35%) and absence of electricity or power cut-off (34%). The study recommends that all teachers should be trained in the use of ICT in both teaching and assessment. Moreover, the challenges observed in the use of ICT should be addressed for effective utilisation and integration of ICT in secondary education.
HUBUNGAN PERILAKU MEROKOK DENGAN MEMORI JANGKA PENDEK PADA REMAJA
Authors: Setianingsih Setianingsih , Purnomo Romadhoni Tri , Qotifah Ninda Lilis , Murtono Agus 
Published: January 2024

Perilaku merokok merupakan kebiasaan buruk yang sering ditemui dalam kehidupan sehari-hari. Dianggap sebagai permasalahan yang dapat mengganggu perkembangan remaja di masa depan dan perubahan tersebut mempengaruhi perilaku anak di lingkungan masyarakat, selain itu dapat mengganggu kesehatan serta faktor risiko dari suatu penyakit tidak menular. Hal tersebut menjadi masalah di seluruh dunia baik negara maju maupun negara berkembang. Penelitian ini bertujuan untuk mengetahui hubungan perilaku merokok dengan memori jangka pendek pada remaja kelas X di SMK Muhammadiyah 1 Klaten Utara. Penelitian ini menggunakan desain deskriptif korelasional dengan pendekatan cross sectional. Populasi penelitian ini adalah remaja laki-laki usia (16-19 tahun). Responden penelitian sebanyak 135 siswa yang diperoleh dengan teknik purposive sampling yang sesuai dengan kriteria inklusi dalam penelitian. Instrumen pengumpulan data menggunakan kuesioner dan tes digit span. Analisa data bivariat menggunakan uji Kendall Tau. Hasil penelitian ini rerata usia 61,43 tahun. Hasil penelitian menunjukkan perilaku merokok pada derajat sedang (34,1 %), memori jangka pendek pada remaja di SMK Muhammadiyah 1 Klaten Utara adalah memori lemah (52,6 %). Hasil uji Kendall Tau menunjukkan ada hubungan antara perilaku merokok dengan memori jangka pendek pada remaja p value 0,00 (p < 0,05). Kesimpulan antara perilaku merokok memiliki hubungan dengan memori jangka pendek pada remaja di SMK Muhammadiyah 1 Klaten Utara.
Hubungan HUBUNGAN INDEKS MASA TUBUH DENGAN PREMENSTRUAL SYNDROME (PMS)
Authors: Haniyah Siti , Dewi Pramesti 
Published: January 2024

PMS often occurs in teenage girls which appears with a set of symptoms both mental and physical and behavioral during the luteal phase of the menstrual cycle around 7-10 days before menstruation and disappears when menstrual blood comes out. One of the factors causing the syndrome is Body Mass Index. The aim of this study was to determine the relationship between Body Mass Index and premenstrual syndrome. The formula used in selecting respondents was total sampling with a cross-sectional approach. The assessment form used is SPAF and data analysis used Spearman rank to measure the relationship between Body Mass Index and PMS in Harapan Bangsa University. The conclusion of this study there is a relationship between BMI and PMS p: 0.00 and the relationship is quite close (0.456). Women with PMS disorders have low serotonin levels which causes early or late ovulation. This can trigger the hormones estrogen and progesterone, which cause complaints such as breast pain and bloating. At the same time, an increase in the hormone prostaglandin causes the uterus to contract which causes abdominal pain during the menstrual cycle.
Keywords: Body Mass Indeks, premenstrual syndrome, female student
HUBUNGAN FATIGUE DENGAN KUALITAS HIDUP PASIEN CA MAMMAE YANG MENJALANI KEMOTERAPI DI RSUP DR. SOERADJI TIRTONEGORO KLATEN
Authors: Susilowati Eni , Nurhidayati Istianna , Suparti Sri 
Published: January 2024

Ca mammae merupakan jenis kanker dengan jumlah prevalensi tertinggi dari seluruh kasus kanker pada perempuan di Indonesia. Data DepKes menyebutkan ca mammae adalah jenis kanker yang paling banyak diderita wanita dengan kontribusi sebesar 42,1% dengan rata-rata kematian 17%. Penatalaksanaan untuk pasien ca mammae adalah kemoterapi. Pasien ca mammae dengan kemoterapi beresiko mengalami beberapa efek samping antara lain fatigue, nyeri, mual serta muntah. Salah satu masalah yang dialami penderita kanker yang melakukan kemoterapi adalah gejala fatigue yang dapat berdampak pada menurunnya kualitas hidup pasien itu sendiri. Penelitian ini bertujuan untuk mengetahui hubungan fatigue dengan kualitas hidup pasien ca mammae yang menjalani kemoterapi di RSUP dr. Soeradji Tirtonegoro Klaten
Jenis penelitian ini adalah deskriptif korelasional dengan pendekatan cross sectional. Teknik pengambilan sampel menggunakan purposive sampling. Sampel yang digunakan sejumlah 40 responden. Instrumen pengumpulan data menggunakan Brief Fatigue Inventory dan EORTC QLQ-C30. Uji statistik bivariat menggunakan kendall tau
Hasil penelitian diperoleh kejadian fatigue pada responden mayoritas adalah fatigue non-severe yaitu sebanyak 33 responden (82,5%), kualitas hidup responden mayoritas baik yaitu sebanyak 27 responden (67,5%), analisis bivariat diperoleh p value sebesar 0,017 (p < 0,05). Kesimpulan penelitian ini adalah ada hubungan fatigue dengan kualitas hidup pasien ca mammae yang menjalani kemoterapi di bangsal RSUP dr. Soeradji Tirtonegoro Klaten
Genetic Parameter Estimation of Teak Clonal Test At 5 Years Old in Wonogiri, Central Java
Authors: Hamdan Hamdan Adma Adinugraha , Mahfudz Mahfudz 
Published: January 2024

Trial research of teak clones was located in Wonogiri, Central Java. This research was conducted in order to evaluate the growth performance of teak clones that can be developed for forest plantation and private forest. Establishment of teak clones test was conducted in 2002 using 20 clones with Randomized Completely Block Design/RCBD consisting of 5 ramets and 5 replications with plant spacing of 2 m x 6 m . The second plot was established in 2005 using 100 clones with RCBD that consisted of 3 ramets and 5 replications with spacing of 2 m x 6 m. The observation and measurement on height and diameter at breast height/dbh were carried out periodically in every year to determine the level of plant growth The results showed that the average growth at the age of 5 years in two test plot clones are height from 8,73 to 9,97 m , tree diameter from 8.61 to 13.14 cm and tree volume estimated 0,046 - 0,103 m3. Estimated heritability clones of tree height and diameter were 0,18; 0,29 in plot 1 and 0,32; 0,38 in plot 2.
Birds Species of Rallidae Family in Forestry and Environment Research and Development Institute of Manado
Authors: Diah Diah Irawati Dwi Arini 
Published: January 2024

This study aims to determine species and conservation status of Rallidae family in Forestry and Environment Research and Development Institute of Manado; also the prospect of its development. This study may provide a source of data and information on the diversity of certain bird species. Observations conducted in June 2015 included the species of birds in Rallidae family found around the Forestry and Environment Research and Development Institute of Manado. Data were analyzed descriptively in the forms of figures and tables. Results showed that there were three species within this family found in Manado Forestry Research Institute. Those were isabelline bush-hen (Amaurornis isabellina), buff-banded rail (Gallirallus philippensis), and Barred Rail (Gallirallus torquatus). All three species are not protected in Indonesia and IUCN categorized them as Least Concern (LC). Isabelline bush-hen is endemic to the island of Sulawesi, while buff-banded rail and barred rail have a wide distribution. Weris has a good prospect to be domesticated.
Distribution of Avifauna in Aketajawe Lolobata National Park Based on Zone and Land Cover Typology
Authors: Supratman Supratman Tabba , Nurrani Lis Nurrani 
Published: January 2024

Aketajawe Lolobata National Park (TNAL) is a protected area for paradise birds, parrots and others North Maluku endemic wildlife. As a former of commercial logging concessions, this areas have been damaged and loss of wildlife habitat. The purpose of this research was to determine bird species of TNAL area based on zone category, this research is important in order to validate data related to the birds species diversity. Data collection used the observation point system with purposive sampling by direct observation and audio. The number of observation points were six points in core zone, ten points in both of jungle and traditional zone, and six points in buffer zone. Research showed that there are 39 species found in the buffer zone, 45 species in jungle and traditional zone, and 19 species in core zone. Wallace’s standardwing (Semioptera wallacei) is one of the 15 endemic species of North Maluku was found along drummer rail (Habroptila wallacii) which is Halmahera’s endemic species. Distribution pattern of birds in TNAL is very varied. The jungle and traditional zone have the amount and the highest species diversity while the highest species variation was in the buffer zone. The natural habitat of bird in this area generally located in open area along former road skid as well as forest edge and only a few were found in primary forest of core zone.
Growth Comparison of Red Jabon in North Bolaang Mongondow and North Minahasa
Authors: Irawan Arif Irawan , Hidayah Hanif Nurul Hidayah 
Published: January 2024

Red Jabon is priority species that projected to be developed in plantation forests of North Minahasa Regency. Red Jabon is can adapt well various environmental conditions. The natural habitat of the red Jabon in North Sulawesi region was known in North Bolaang Mongondow. This study aimed to compare the growth of red jabon at the age of 1 year in North Minahasa Regency and North Bolaang Mongondow. The experiment was conducted in two (2) locations i.e. in Talawaan Village (North Minahasa Regency) and Nunuka Village (North Bolaang Mongondow). Two independent samples t test was conducted to determine the differences in height and diameter growth parameters at two test sites.The results showed that there was no difference in the growth of red Jabon between North Minahasa and North Bolaang Mongondow. The average height and diameter of red Jabon in North Minahasa Regency is at 215.84 cm and 4.34 cm, while the same parameters of North Bolaang Mongondow amounted to 231.79 cm and 4.14 cm. The development efforts on the plantations of red Jabon North Minahasa Regency need to be improved because of the environmental conditions in this region is very suitable for the growth of red Jabon.
The profitability of artificial and natural regeneration: A forest investment comparison of Poland and the U.S. South
Authors: Chudy Rafał , Cubbage Frederick , Siry Jacek , Chudy Jacek 
Published: January 2024

The historical development of silviculture has been closely related to an increasing need for timber, which resulted in more planted forests and artificial regeneration over time. The idea of natural regeneration through shelterwood cutting was often not accepted by forest owners as a management practice because of inadequate financial returns and less certain outcomes. Despite the evolving dominance of planted forests, questions remain if the lower costs of natural regeneration may still provide sufficient profitability of forest investments. In this paper, the profitability of planted versus natural forest management in Poland and the U.S. South was examined. A discounted cash flow model was developed to evaluate the profitability of artificial and natural regeneration in hypothetical Scots and loblolly pine stands in Poland and the U.S. South, respectively, and hardwood stands (dominated by oak spp.) in both countries. The results have shown that for both countries and species, natural regeneration regimes produce higher internal rates of return (IRR), largely due to less expensive establishment costs. The largest difference in returns is observed for hardwood in the US South (97 basis points, bps, or almost 1 percentage point), followed by pine in the US South (84 bps) and pine and hardwood in Poland (both ca. 70 bps). Southern pines in the U.S. South may have larger net present values (NPV) at moderate discount rates, as well as provide more certain wood production outcomes, which have contributed to their pervasive adoption. We conclude that natural stand forest management, in addition to better rates of return, may bring other non-financial benefits (e.g., genetic diversity, resilience), which may support forest owners and the environment, especially under changing climate conditions. Nevertheless, the regeneration method and its feasibility and profitability should be carefully considered on a case-by-case basis for each forest investment.
Small cooperative activity of old rat hepatocytes may depend on composition of the intercellular medium
Authors: Brodsky Vsevolod Y. , Nechaeva Natalia V. , Zvezdina Natalia D. , Novikova Tatjana E. , Gvasava Inessa G. , Fateeva Valentina I. , Malchenko Ludmila A. 
Published: April 2004

AbstractUltradian oscillations of protein synthesis were used as a marker of hepatocyte synchronous cooperative activity producing a common rhythm in vitro; amplitude of the rhythm defines expression of the cell cooperation. Dense synchronous and sparse non‐synchronous rat hepatocyte cultures on slides in a serum‐free incubation medium 199 supplemented with 0.2 mg/ml albumin and 0.5 μg/ml insulin have been studied. The amplitude of the rhythm averaged ∼2× in dense cultures of young (3 month old) rats than in old (2 year old) rats. But some cultures of young rats had the amplitude patterns similar to cultures of old rats, and vice versa. Addition to the medium of either 0.3 μM bovine brain gangliosides or 2 μM phenylephrine resulted in increase of the oscillation amplitude in dense cultures of old rats to the level inherent in young ones. Addition to the medium of 10% rat blood serum in non‐synchronous sparse cultures from young rats resulted in detection of a protein synthetic rhythm. Although after serum from young rats, the rhythm expression was high, the rhythm after serum from old rats had been given was weak. Addition of gangliosides to old‐rat serum resulted in synchronization of sparse cultures with amplitudes inherent of young‐rat serum. The data tend to the conclusion that cell cooperation depends to a greater extent on the composition of the medium rather than on the age of the cell or animal.
FRET Sensor‐Modified Synthetic Hydrogels for Real‐Time Monitoring of Cell‐Derived Matrix Metalloproteinase Activity using Fluorescence Lifetime Imaging
Authors: Yan Ziqian , Kavanagh Thomas , da Silva Harrabi Ricardo , Lust Suzette T. , Tang Chunling , Beavil Rebecca L. , Müller Manuel M. , Beavil Andrew J. , Ameer‐Beg Simon , da Silva Ricardo M.P. , Gentleman Eileen 
Published: January 2024

AbstractMatrix remodeling plays central roles in a range of physiological and pathological processes and is driven predominantly by the activity of matrix metalloproteinases (MMPs), which degrade extracellular matrix (ECM) proteins. How MMPs regulate cell and tissue dynamics is not well understood as in vivo approaches are lacking and many in vitro strategies cannot provide high‐resolution, quantitative measures of enzyme activity in situ within tissue‐like 3D microenvironments. Here, a Förster resonance energy transfer (FRET) sensor of MMP activity is incorporated into fully synthetic hydrogels that mimic many properties of the native ECM. Fluorescence lifetime imaging is then used to provide a real‐time, fluorophore concentration‐independent quantification of MMP activity, establishing a highly accurate, readily adaptable platform for studying MMP dynamics in situ. MCF7 human breast cancer cells encapsulated within hydrogels are then used to detect MMP activity both locally, at the sub‐micron level, and within the bulk hydrogel. This versatile platform may find use in a range of biological studies to explore questions in the dynamics of cancer metastasis, development, and tissue repair by providing high‐resolution, quantitative, and in situ readouts of local MMP activity within native tissue‐like environments.
Near‐Field Nanoimaging of Colloidal Transition Metal Dichalcogenide Waveguides
Authors: Li Jingang , Yang Rundi , Yao Kan , Huang Yun , Rho Yoonsoo , Fan Donglei Emma , Zheng Yuebing , Grigoropoulos Costas P. 
Published: January 2024

AbstractBulk transition metal dichalcogenide (TMDC) nanostructures are regarded as promising material candidates for integrated photonics due to their high refractive index at the near‐infrared wavelengths. In this work, colloidal TMDC waveguides with tailorable dimensions are prepared by a scalable synthetic approach. The optical waveguiding properties of colloidal nanowires are studied by the near‐field nanoimaging technique. In addition to dependence on thickness and wavelength, the excitonic responses and resultant waveguide modes in TMDC nanowires can be modulated by the environmental temperature. With the high‐throughput production and tunable optical properties, colloidal TMDC nanowires highlight the potential for active optical components and integrated photonic devices.
Dissecting the Interplay Mechanism among Process Parameters toward the Biofabrication of High‐Quality Shapes in Embedded Bioprinting
Authors: Wu Yang , Yang Xue , Gupta Deepak , Alioglu Mecit Altan , Qin Minghao , Ozbolat Veli , Li Yao , Ozbolat Ibrahim T. 
Published: January 2024

AbstractEmbedded bioprinting overcomes the barriers associated with the conventional extrusion‐based bioprinting process as it enables the direct deposition of bioinks in 3D inside a support bath by providing in situ self‐support for deposited bioinks during bioprinting to prevent their collapse and deformation. Embedded bioprinting improves the shape quality of bioprinted constructs made up of soft materials and low‐viscosity bioinks, leading to a promising strategy for better anatomical mimicry of tissues or organs. Herein, the interplay mechanism among the printing process parameters toward improved shape quality is critically reviewed. The impact of material properties of the support bath and bioink, printing conditions, cross–linking mechanisms, and post‐printing treatment methods, on the printing fidelity, stability, and resolution of the structures is meticulously dissected and thoroughly discussed. Further, the potential scope and applications of this technology in the fields of bioprinting and regenerative medicine are presented. Finally, outstanding challenges and opportunities of embedded bioprinting as well as its promise for fabricating functional solid organs in the future are discussed.
Cancer‐Thylakoid Hybrid Membrane Camouflaged Thulium Oxide Nanoparticles with Oxygen Self‐Supply Capability for Tumor‐Homing Phototherapy
Authors: Zuo Yu‐Cheng , Huo Cong‐Min , Chen Yu , Ding Peng‐Li , Tong Si‐Ye , Xue Wei , Zhu Jing‐Yi 
Published: January 2024

AbstractNanomaterials that generate reactive oxygen species (ROS) upon light irradiation have significant applications in various fields, including photodynamic therapy (PDT) that is widely recognized as a highly momentous strategy for the eradication of cancer cells. However, the ROS production rate of photosensitizers, as well as the tumor hypoxia environment, are two major challenges that restrict the widespread application of PDT. In this study, a cancer‐thylakoid hybrid membrane‐camouflaged thulium oxide nanoparticles (Tm2O3) for tumor‐homing phototherapy through dual‐stage‐light‐guided ROS generation and oxygen self‐supply is developed. Tm2O3 as a type II photosensitizer are viable for NIR‐stimulated ROS generation due to the unique energy levels, large absorption cross section, and long lifetime of the 3H4 state of Tm ions. The thylakoid membrane (TK) plays a catalase‐like role in converting hydrogen peroxide into oxygen and also acts as a natural photosensitizer that can generate lethal ROS through electron transfer when exposed to light. In addition, fluorescence dye DiR is embedded in the hybrid membrane for in vivo tracing as well as photothermal therapy. Results show that tumors in Tm2O3@TK‐M/DiR group are effectively ablated following dual‐stage‐light irradiation, highlighting the promising potential of rare‐earth element‐based type II photosensitizers in various applications.
Tailoring Biomaterials Ameliorate Inflammatory Bone Loss
Authors: Cheng Shi , Wang Kong‐Huai , Zhou Lu , Sun Zhi‐Jun , Zhang Lu 
Published: January 2024

AbstractInflammatory diseases, such as rheumatoid arthritis, periodontitis, chronic obstructive pulmonary disease, and celiac disease, disrupt the delicate balance between bone resorption and formation, leading to inflammatory bone loss. Conventional approaches to tackle this issue encompass pharmaceutical interventions and surgical procedures. Nevertheless, pharmaceutical interventions exhibit limited efficacy, while surgical treatments impose trauma and significant financial burden upon patients. Biomaterials show outstanding spatiotemporal controllability, possess a remarkable specific surface area, and demonstrate exceptional reactivity. In the present era, the advancement of emerging biomaterials has bestowed upon more efficacious solutions for combatting the detrimental consequences of inflammatory bone loss. In this review, the advances of biomaterials for ameliorating inflammatory bone loss are listed. Additionally, the advantages and disadvantages of various biomaterials‐mediated strategies are summarized. Finally, the challenges and perspectives of biomaterials are analyzed. This review aims to provide new possibilities for developing more advanced biomaterials toward inflammatory bone loss.