bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lichen planus: A Systematic Review
Authors: Garbacz Karolina , Maciąg Maria , Pasztelan Małgorzata , Pulikowski Jarosław , Słaboń Małgorzata , Sobczyk Maciej , Muca Aleksandra , Marczak Aleksandra , Krawczuk vel Walczuk Julia , Baran Joanna 
Published: February 2024

Lichen planus (LP) is a chronic skin, mucous membrane, and nail disease. Lichen planus is a rare skin condition occurring in less than 1% of the general population, affecting both children and adults. Oral lichen planus (OLP) involvement is much more common. It is an autoimmune disease caused by T lymphocytes, with epigenetic factors playing a significant role in the development of autoimmune skin diseases. MicroRNAs (miRNAs), a group of non-coding RNAs, play a substantial role in regulating the immune response.1 The etiology of lichen planus in not fully understood. It can be triggered by antihypertensive drugs, beta-blockers, infections, viral hepatitis, psychological stress, and others. Cases of lichen planus appearing after recovering from COVID-19 have been reported, as well as a significant increase in cases after COVID-19 vaccination.2–5 Diagnosis is based on clinical presenstation and characteristic histopathological findings. The disease is often self-limiting, accompanied by persistent itching and painful erosions of the mucous membrane, affecting the patient’s quality of life and mental well-being. First-line treatments inculde topical corticosteroids and/or oral corticosteroids. There are reports of new potential treatments, such as biologic drugs (anti-IL12/13, anti-IL17) and Janus kinase inhibitors. Consequently, a dramatic change in lichen planus treatment can be expected in the near future. The majority of patients suffering from lichen planus develop metabolic syndrome which is the cause of other diseases. This article provides a comprehensive overview of current knowledge about lichen planus and its variants.
Finding Regions of Counterfactual Explanations via Robust Optimization
Authors: Maragno Donato , Kurtz Jannis , Röber Tabea E. , Goedhart Rob , Birbil Ş. İlker , den Hertog Dick 
Published: February 2024

Counterfactual explanations (CEs) play an important role in detecting bias and improving the explainability of data-driven classification models. A CE is a minimal perturbed data point for which the decision of the model changes. Most of the existing methods can only provide one CE, which may not be achievable for the user. In this work, we derive an iterative method to calculate robust CEs (i.e., CEs that remain valid even after the features are slightly perturbed). To this end, our method provides a whole region of CEs, allowing the user to choose a suitable recourse to obtain a desired outcome. We use algorithmic ideas from robust optimization and prove convergence results for the most common machine learning methods, including decision trees, tree ensembles, and neural networks. Our experiments show that our method can efficiently generate globally optimal robust CEs for a variety of common data sets and classification models. History: Accepted by Andrea Lodi, Area Editor for Design & Analysis of Algorithms—Discrete. Funding: This work was supported by the Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Grant OCENW.GROOT.2019.015, Optimization for and with Machine Learning (OPTIMAL)]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/ijoc.2023.0153 .
Mapping U.S.–China Technology Decoupling: Policies, Innovation, and Firm Performance
Authors: Han Pengfei , Jiang Wei , Mei Danqing 
Published: February 2024

We develop measures of technology decoupling and dependence between the United States and China based on combined patent data. The first two decades of the century witnessed a steady increase in technology integration (or less decoupling), but China’s dependence on the United States increased (decreased) during the first (second) decade. Firms covered by China’s Strategic Emerging Industries policies became less decoupled with the United States, gained cash flows, and gained valuation, but they saw no improvement in either innovation output/quality or productivity. Post-U.S. sanctions, firms in sanctioned sectors and their downstream suffered in performance but also became less decoupled with the United States. However, firms in the upstream of the sanctioned sectors improved productivity and produced more high-quality innovations. This paper was accepted by William Cong, finance. Funding: P. Han acknowledges financial support from China’s Natural Science Foundation [Grant 72103003]. W. Jiang acknowledges financial support from the Chazen Institute of Global Business at Columbia Business School. D. Mei acknowledges financial support from the Association of Southeast Asian Nations Business Research Initiative [grant with Cheung Kong Graduate School of Business and Singapore Management University]. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.02057 .
Minimax Regret Robust Screening with Moment Information
Authors: Wang Shixin , Liu Shaoxuan , Zhang Jiawei 
Published: February 2024

Problem definition: We study a robust screening problem where a seller attempts to sell a product to a buyer knowing only the moment and support information of the buyer’s valuation distribution. The objective is to maximize the competitive ratio relative to an optimal hindsight policy equipped with full valuation information. Methodology/results: We formulate the robust screening problem as a linear programming problem, which can be solved efficiently if the support of the buyer’s valuation is finite. When the support of the buyer’s valuation is continuous and the seller knows the mean and the upper and lower bounds of the support for the buyer’s valuation, we show that the optimal payment is a piecewise polynomial function of the valuation with a degree of at most two. Moreover, we derive the closed-form competitive ratio corresponding to the optimal mechanism. The optimal mechanism can be implemented by a randomized pricing mechanism whose price density function is a piecewise inverse function adjusted by a constant. When the mean and variance are known to the seller, we propose a feasible piecewise polynomial approximation of the optimal payment function with a degree of at most three. We also demonstrate that the optimal competitive ratio exhibits a logarithmic decay with respect to the coefficient of variation of the buyer’s valuation distribution. Managerial implications: Our general framework provides an approach to investigating the value of moment information in the robust screening problem. We establish that even a loose upper bound of support or a large variance can guarantee a good competitive ratio. Funding: The research of S. Wang is partially supported by the National Natural Science Foundation of China [Grant 72394395]. The research of S. Liu is partly supported by the National Natural Science Foundation of China [Grant NSFC-72072117]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.0072 .
Cognitive Economy and Product Categorization
Authors: Piazzai Michele , Liu Min , Montauti Martina 
Published: February 2024

In mediated markets, the categorization of products by mediators is critical to efficient interaction between producers and consumers. As organizational research tends to focus on the consequences of categorization rather than its antecedents, however, we know relatively little about why mediators assign one category label or another to a product. In this study, we argue that two informational properties of labels, specificity and distinctiveness, determine the outcomes of mediators’ categorization decisions. Our analysis of product categorization decisions made by members of an online music community, 2000–2020, supports this argument. We find that a label’s odds of being assigned to a product increase (a) if this label encodes information that is neither too similar nor too different from that which is encoded by a superordinate label, that is, it has moderate specificity; and (b) if it encodes information that differs as much as possible from that which is encoded by horizontally related labels, that is, it has maximal distinctiveness. These findings persist after controlling for other possible determinants of mediators’ categorization decisions, including producers’ claims to labels, products’ typicality, and mediators’ expertise. Funding: M. Piazzai received funding from the Community of Madrid [EPUC3M12, VPRICIT] and the Spanish Ministry of Science and Innovation [RYC2021-032325-I]. M. Liu received funding from Durham University Business School. Supplemental Material: The e-companion is available at https://doi.org/10.1287/orsc.2021.15751 .
Practice tutors' readiness to support nursing students who require reasonable adjustments for clinical placement
Authors: King Liz 
Published: February 2024

Background:Preregistration nursing students (trainee nursing associates and student nurses) may have a disability or impairment that requires reasonable adjustments while they are on clinical placement. At The Open University, practice tutors support nursing students on clinical placement, which includes overseeing the facilitation of any such reasonable adjustments. However, they may not feel prepared to provide this support.Method:A qualitative approach with a broad interpretivist paradigm was adopted. Data were collected from three focus groups that included a total of 10 nursing practice tutors. Audio data were transcribed and analysed using complete coding followed by thematic analysis.Findings:Three main themes were identified – it's complex; impact of engagement; and a cohesive approach – along with associated subthemes.Conclusion:Despite their clear interest in helping nursing students who require reasonable adjustments for practice-based learning, practice tutors can be hindered by barriers resulting from a lack of both training and guidelines. The complexity of the practice tutor role and student issues can compound this. Consistency in practice tutor training is recommended, as well as regular access to peer support to address these difficulties and develop the skills and knowledge.
A narrative review of patients' lived experience of having a pressure injury
Authors: Ibeh Chioma , Hambridge Kevin 
Published: February 2024

Aim: To explore patients' experiences of living with pressure injuries. Design: A qualitative narrative review and thematic synthesis of qualitative research studies. Data sources: Six electronic databases were searched: Medline, CINAHL, Scopus, Web of Science, Embase, and Google Scholar (for grey literature). The search was conducted between October 2022 and April 2023. Setting: Acute, community and care home settings across the UK, France, Belgium and the US. Review methods: The PRISMA checklist for reporting systematic reviews was used. The included studies were evaluated for quality using the CASP tool. The Joanna Briggs Institute data extraction tool was used to extract data from the included studies. Thematic synthesis was used to identify themes to present a coherent and nuanced understanding of patients' experiences of living with pressure injuries. Results: Nine studies involving 244 participants, aged 21 to 101, with pressure injuries, met the inclusion criteria. Three key themes emerged using thematic analysis: physiological, emotional and psychological, and social effects. Within these themes, subthemes such as endless pain and discomfort, loss of mobility and independence, and social isolation were dominant in all aspects of the lives of patients living with pressure injuries. Conclusions: This narrative review gives clear and multifaceted insight into the impact of pressure injuries on individuals' lives, emphasising the necessity for patient-centred care and the integration of evidence-based tools for effective pain management and risk assessment. The impact of pain on emotional and psychological wellbeing was significant, and the financial implications are scarcely known. Future research is needed to explore the experiences of younger adults and the financial consequences of living with pressure injuries.
My Experiences as a Researcher
Authors: Linnenkamp Brad 
Published: February 2024

Abstract
My name is Brad Linnenkamp and, in this article, I will share about my lived experience as a researcher, including my experience transitioning from an advocate to a researcher. I currently work as a paid researcher at the Kansas University Center on Developmental Disabilities (KUCDD) and have a long history of engagement in disability advocacy. I think it’s been really important as a person with a disability to be involved in the research and being a researcher gives me an opportunity to shape what is happening and educate individuals with and without disabilities and also teach them how to communicate in a way that is easier for others to understand. I also share about barriers I have faced, especially when getting started and various projects I have worked on. All the research in its own way really means something to me, and it means something to me to be a part of all parts of research.
Pauline Bosma’s Tips on How to Be a Good Research Ally
Authors: Bosma Pauline 
Published: February 2024

Abstract
My name is Pauline Bosma and in this article I share my lived experience as a researcher. I have worked on projects that support people with disabilities to recognize, respond to, and report abuse. I am now leading a research study with other self-advocates to interview LGBT adults with intellectual and developmental disabilities about their lives. I have also worked on projects with the Social Security Administration. I like doing research because it helps people. In this article, I also offer recommendations for other research teams who want to practice inclusive research.
Feeding and swallowing outcomes of children receiving long-term ventilation: A scoping review protocol
Authors: Lee Sabrena , Marshall Jeanne , Clarke Michael , Smith Christina H. 
Published: February 2024

Background
The last three decades have seen a growth in the number of children requiring long-term ventilation. Children with long-term ventilation present with underlying respiratory and neurological conditions that place them at risk of feeding and swallowing difficulties. To date, a scoping review or systematic review investigating the feeding and swallowing outcomes of children with long-term ventilation needs has not been conducted.

Aims
This paper describes a protocol for a scoping review of the feeding and swallowing outcomes of children receiving long-term ventilation.

Methods
This scoping review protocol will utilize the Joanna Briggs Institute scoping review methodology guideline. Our review will focus on the feeding and swallowing outcomes of children aged 0 to 18 years with long-term ventilation needs. A full search strategy initially created by the authors and a research librarian was conducted on the PubMed database. Following this, pilot testing took place to determine discrepancies in eligibility criteria. A full search strategy will be conducted across several databases. A data extraction form has been developed by the authors and will be used during the scoping review process.

Discussion
This protocol has been created to provide a rigorous and comprehensive basis for undertaking a scoping review. All necessary steps have been completed in order to commence the scoping review.

Registration
This scoping review protocol was registered on Open Science Framework on the 26th November 2021 (Registration DOI 10.17605/OSF.IO/NQBPD).
Effectiveness of online training in improving primary care doctors’ competency in brief tobacco interventions: A cluster-randomized controlled trial of WHO modules in Delta State, Nigeria
Authors: Moeteke Nnamdi Stephen , Oyibo Patrick , Ochei Oboratare , Ntaji Maureen Iru , Awunor Nyemike Simeon , Adeyemi Mitchell Oritsewino , Enemuwe Ibobo Mike , Agbatutu Eseoghene , Adesoye Oluwaseun Opeyemi 
Published: February 2024

Background
The World Health Organization (WHO) strongly recommends that brief tobacco interventions should be routinely offered in primary care. However, medical doctors do not consistently and effectively intervene during their encounters with cigarette smokers. There is a paucity of studies assessing the effect of training on the tobacco intervention competency of primary care doctors in Nigeria.

Aim
To evaluate the effectiveness of online training in improving competency in brief tobacco interventions among primary care doctors in Delta State, Nigeria.

Methods
A cluster-randomized controlled trial was conducted among eligible doctors working in government-owned facilities. The 22 eligible Local Government Areas (LGAs) served as clusters. The intervention group received a WHO six-hour online course on brief tobacco cessation intervention, delivered via Zoom. The control group received no intervention. A structured questionnaire was sent to participants via WhatsApp before and six months after the training. The primary outcome variables were scores for knowledge, attitude, self-efficacy, and practice. Differences in change of scores between intervention and control groups were assessed with t-test. To adjust for clustering, these inter-group differences were further analyzed using linear mixed-effects regression modeling with study condition modeled as a fixed effect, and LGA of practice entered as a random effect.

Results
The intervention group had a significantly higher mean of change in scores for knowledge (effect size 0.344) and confidence (effect size 0.52).

Conclusion
The study shows that training, even online, positively affects clinician competency in brief tobacco intervention. This is important for primary care systems in developing countries. Mandatory in-service training and promotion of the WHO modules are recommended.
The impact of the COVID-19 virus and pandemic on healthcare utilization, access, delivery, experiences, and outcomes in the spinal cord injuries/dysfunction population: A scoping review study
Authors: Senthinathan Arrani , Cimino Stephanie , Jaglal Susan B. , Craven B. Catharine , Tu Karen , Guilcher Sara 
Published: February 2024

Background
Individuals with spinal cord injuries or disease (SCI/D) require frequent healthcare services. The COVID-19 pandemic may have impacted healthcare. Furthermore, due to secondary health conditions and comorbidities persons with SCI/D are at increased risk of experiencing severe symptoms or outcomes if infected with the COVID-19 virus. It is unclear to what extent research has investigated the pandemic and virus impacts on the SCI/D population.

Objective
To identify and summarize what is reported in the literature on the impact the COVID-19 virus and pandemic had on healthcare, health outcomes, and experiences in the adult SCI/D population.

Methods
Electronic databases and grey literature were searched for articles that included an adult population with a SCI/D and investigated the impact the COVID-19 virus and pandemic had on healthcare-related outcomes and experiences. Articles were double screened, and data were extracted, and synthesized to provide a descriptive summary of the findings.

Results
Twenty-four studies were included in this review with eight qualitative, fifteen quantitative, and one mixed methods study. Sixteen studies investigated healthcare utilization/access; nine investigated care delivery, nine investigated patient outcomes, and eight investigated patient experiences, with multiple studies spanning different categories of investigation. The pandemic was detrimental to healthcare utilization, access, and outcomes, but no studies quantified these changes. Virtual care was well-received by the SCI/D population to maintain continuity of care. The SCI/D population had issues with maintaining caregiving support. It was unclear if the COVID-19 virus infection impacted individuals with SCI/D differently than the general population.

Conclusions
This scoping review found the pandemic negatively impacted multiple aspects of healthcare in individuals with SCI/D, however further investigation on health outcomes is required. More research, particularly large-scale quantitative studies, investigating healthcare access, utilization, and delivery, as well as patient outcomes and experiences is needed to improve care in the SCI/D population post-pandemic onset.
Prospective evaluation of deep learning image reconstruction for Lung-RADS and automatic nodule volumetry on ultralow-dose chest CT
Authors: Yoo Seung-Jin , Park Young Sik , Choi Hyewon , Kim Da Som , Goo Jin Mo , Yoon Soon Ho 
Published: February 2024

Purpose
To prospectively evaluate whether Lung-RADS classification and volumetric nodule assessment were feasible with ultralow-dose (ULD) chest CT scans with deep learning image reconstruction (DLIR).

Methods
The institutional review board approved this prospective study. This study included 40 patients (mean age, 66±12 years; 21 women). Participants sequentially underwent LDCT and ULDCT (CTDIvol, 0.96±0.15 mGy and 0.12±0.01 mGy) scans reconstructed with the adaptive statistical iterative reconstruction-V 50% (ASIR-V50) and DLIR. CT image quality was compared subjectively and objectively. The pulmonary nodules were assessed visually by two readers using the Lung-RADS 1.1 and automatically using a computerized assisted tool.

Results
DLIR provided a significantly higher signal-to-noise ratio for LDCT and ULDCT images than ASIR-V50 (all P < .001). In general, DLIR showed superior subjective image quality for ULDCT images (P < .001) and comparable quality for LDCT images compared to ASIR-V50 (P = .01–1). The per-nodule sensitivities of observers for Lung-RADS category 3–4 nodules were 70.6–88.2% and 64.7–82.4% for DLIR-LDCT and DLIR-ULDCT images (P = 1) and categories were mostly concordant within observers. The per-nodule sensitivities of the computer-assisted detection for nodules ≥4 mm were 72.1% and 67.4% on DLIR-LDCT and ULDCT images (P = .50). The 95% limits of agreement for nodule volume differences between DLIR-LDCT and ULDCT images (-85.6 to 78.7 mm3) was similar to the within-scan nodule volume differences between DLIR- and ASIR-V50-LDCT images (-63.9 to 78.5 mm3), with volume differences smaller than 25% in 88.5% and 92.3% of nodules, respectively (P = .65).

Conclusion
DLIR enabled comparable Lung-RADS and volumetric nodule assessments on ULDCT images to LDCT images.
A retrospective cohort study to observe the efficacy and safety of Endoscopic Submucosal Dissection (ESD) with adjuvant radiotherapy for T1a-MM/T1b-SM Esophageal Squamous Cell Carcinoma (ESCC)
Authors: Lu Hongna , Bei Yanping , Wang Chunnian , Deng Xi , Hu QinQin , Guo Wenying , Zhang Xuesong 
Published: February 2024

Background and aim
The clinical outcome of endoscopy submucosal dissection with subsequent radiotherapy for esophageal squamous cell carcinoma remain unclear. In this study we aim to investigate the efficacy and safety of endoscopic submucosal dissection with adjuvant radiotherapy in the treatment of superficial esophageal squamous cell carcinoma involving the muscularis mucosae (T1a-MM) or the submucosa < 200 μm (T1b-SM1).

Methods
We analyzed 20 patients with pathologically confirmed T1a-MM or T1b-SM1 esophageal squamous cell carcinoma treated by endoscopic submucosal dissection from 2016 to 2020 in Lihuili Hospital, 9 patients received adjuvant radiotherapy (RT group) and 11 patients received did not (non-RT group).

Results
All 20 patients underwent en bloc resection, and both the vertical and horizontal margins were negative. There was no recurrence or lymph node metastasis in the RT group, and no serious complications or death were observed. In the non-RT group, 2 patients had local recurrence and 1 had distant metastasis. None of the 20 patients died of esophageal carcinoma.

Conclusions
Adjuvant radiotherapy following endoscopic submucosal dissection may be a safe and effective method for the treatment of T1a-MM/T1b-SM1 superficial esophageal squamous cell carcinoma.