bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing spatial omics resolution by pseudo-interstitial pixels inference
Authors: Mendoza-Parra Marco Antonio , Duvina Maximilien , Galindo-Albarrán Ariel 
Published: January 2025

AbstractMotivationSpatially resolved omics technologies are enhancing our understanding of tissues architecture. Despite major technological improvements, gaining in spatial resolution becomes experimentally expensive, while generating spatial landscapes at moderate resolution combined with computational methods for depixelating data represent a cost-effective strategy allowing to enlarge the number of experiments to be performed.ResultsWe have developed a computational strategy able to gain several-folds of resolution by inferring pseudo-interstitial pixels from their closest neighbors. This strategy has been validated in the context of public spatial transcriptomics data issued from melanoma, and human brain cortex tissue sections, by improving the identification of distinct tissue substructures. Furthermore, this methodology has been used for enhancing the resolution of consecutive sections collected from human brain organoids, as a way to demonstrate that a moderate resolution technology, combined with spatial depixelation processing allows to properly discern molecular tissue structures even in small tissues.Contactmmendoza@genoscope.cns.fr
Epigenetic Control of TERRA by FTSJ3 is Critical for Telomerase-Driven Cancers
Authors: Price Jared D.W. , Vizeacoumar Frederick S. , Abuhussein Omar , Maranda Vincent , Zhang Yue , Adachi Hironori , Kyrylenko Liliia , Rangel-Pozzo Aline , Dong He , Gong Li Hui , Walke Prachi , Ganapathysamy Ashtalakshmi , Denomy Connor , Freywald Tanya , Dahiya Renuka , Elhasasna Hussain , Saxena Anjali , Vizeacoumar Jeff P. , Patel Hardikkumar , Rajamanickam Karthic , Nguyen Kathryn , de Oliveira Diego M. , Lazell-Wright Mary , Morales Alain Morejon , Aggarwal Aanchal , Xu Jia Lin , Alli Nezeka , Munhoz Erika P. , Gao Peng , Salsman Jayme , Dahiya Dinesh , Gonzalez-Lopez Cristina , Thibault Patricia , Levin Michael , Dellaire Graham , Jette Nicholas , Groot Gary , Krishnan Anand , Ahmed Shahid , Eskiw Christopher , Barakat Khaled H. , Wu Yuliang , DePinho Ronald A. , Mai Sabine , Yu Yi-Tao , Wong Judy M.Y. , Freywald Andrew , Vizeacoumar Franco J. 
Published: January 2025

SummaryTelomerase reverse transcriptase (hTERT) overexpression, a hallmark of most cancers, drives tumorigenesis by enabling limitless replicative potential. Direct targeting of hTERT is challenging, necessitating alternative strategies. Through genome-wide synthetic dosage lethality (SDL) screening in cancer models, including patient-derived organoids, we identify FTSJ3, an RNA 2’-O-methyltransferase, as a critical vulnerability in hTERT-overexpressing cells. FTSJ3 methylates telomeric repeat-containing RNA (TERRA), a modification essential for recruiting SUV39H1 to telomeric ends to mediate H3K9 trimethylation and establish stable heterochromatin. Loss of FTSJ3 disrupts this cascade, impairing H3K9 trimethylation, HP1-alpha recruitment, and telomeric heterochromatin maintenance. Notably, this reveals an unexpected dependency on TERRA methylation for telomeric heterochromatin stability in hTERT-driven cancers. Non-malignant cells, lacking telomerase activity andde novotelomere repeat synthesis, are unaffected by FTSJ3 suppression. Our findings establish the FTSJ3/TERRA/SUV39H1 axis as a critical mechanism supporting telomeric heterochromatin stability in hTERT-driven cancers. This telomere-directed epigenetic strategy provides a robust framework for translational therapeutic innovation.
Behavior Outpaces Form when Linking Traits to Ecological Responses within Populations: A Meta-Analysis
Authors: Rota Thibaut , Raffard Allan , Lang Iris , Petitjean Quentin , Jacquin Lisa , Dézerald Olivier , Blanchet Simon , Hendry Andrew P. , Céréghino Régis 
Published: January 2025

AbstractIntraspecific trait variability (ITV) is an important aspect of community ecology, but we still have a poor understanding of what drives the magnitude of relationships between ITV and ecological dynamics. In order to guide ecologists interested in unravelling the ecological implications of ITV, we asked whether relationships’ magnitudes differ (i) between intraspecific levels (among-vs. within- populations), (ii) among ecological responses spanning levels of biological organization (from individual performances to ecosystem functioning), and (iii) among trait categories (morphology, physiology and behavior). We performed a meta-analysis synthesizing a thousand effect sizes from nearly two-hundred studies, encompassing relationships between traits measured among individuals or populations of animals and a broad range of ecological responses. The average effect size was |r| = 0.24 [0.20 – 0.27] (95% confidence intervals). Within populations, relationships’ magnitudes were higher for ecological performance (foraging, diet), community and ecosystem responses than for fitness (reproduction). Relationships were 28% stronger for physiological and behavioral traits than for morphological traits. Our meta-analysis confirms the central aspect of ITV within populations of animals to drive ecological dynamics, and emphasizes physiological and behavioral traits to enhance the integration between the individual component of diversity and processes at community and ecosystem-levels.
Impaired thalamic burst firing in Fragile X syndrome
Authors: O’Shea Ronan T. , Priebe Nicholas J. , Brager Darrin H. 
Published: January 2025

AbstractThe thalamus performs a critical role in sensory processing by gating the flow of sensory information to the neocortex and directing sensory-driven behaviors; functions which are disrupted in people with autism spectrum disorders (ASD). We have identified cellular changes in thalamic neurons in a mouse model of Fragile X syndrome (FX), the leading monogenic cause of ASD, that alter how the thalamus transmits sensory information to neocortical circuits. In awake animals, thalamic relay cells gate input by shifting between two firing modes: burst and tonic. Relay cells in FX mice, however, do not shift between these modes and instead operate primarily in the tonic mode. We demonstrate that the lack of burst mode firing is caused by a shift in the voltage sensitivity for the Ca2+-dependent low threshold spike, which underlies normal burst firing.
Emotional intelligence and academic engagement of graduate students: the moderating role of digital learning support
Authors: Falola Hezekiah , Joel Opeyemi Olunike , Akinbode James , Ojebola Oluwatunmise 
Published: January 2025

PurposeThis study examined the effect of emotional intelligence on graduate students' academic engagement in Ogun State, Nigeria. This study also explored the moderating role of digital learning support in the relationship between emotional intelligence and academic engagement.Design/methodology/approachA descriptive design was used, with purposive and convenient sampling methods were adopted to select the respondents. A total of 341 graduate students were drawn from different schools of postgraduate studies at selected universities in Nigeria. SmartPLS (3.0) was used to explore the relationships between the variables.FindingsThe results revealed that emotional intelligence dimensions significantly influence graduate students' academic engagement. In addition, digital learning support positively moderated the relationship between emotional intelligence and students' academic engagement. Further, to the empirical evidence from the findings, the study concludes that digital learning support moderates the relationship between emotional intelligence and students' academic engagement.Research limitations/implicationsIt is impossible to extrapolate the findings from the research to other industries in Nigeria. Practical Implication: It is recommended that the leadership of graduate schools pay attention to a digital learning support system that enhances emotional intelligence and will stimulate productive research activities, practical engagement and academic excellence.Originality/valueThis study contributes significantly by filling a research lacuna in strategic human resource management (HRM), personnel psychology and organisational behaviour literature within the context of private universities in Nigeria. This study advances the literature by demonstrating how digital learning support moderates the relationship between emotional intelligence and graduate students' academic engagement.
Modelling the environmental performance of logistics distribution processes: a business case in the agri-food supply chain
Authors: Barbieri Federico , Cannava Luca , Colicchia Claudia , Perotti Sara 
Published: January 2025

PurposeLogistics practitioners face a significant challenge in meeting local and international regulations and the United Nations' Sustainable Development Goals (SDGs) due to the complexities of measuring and assessing the CO2e emissions of logistics processes. This challenge is pronounced in distribution processes, where the literature currently lacks a structured approach based on existing guidelines and regulations or real-case implementation examples.Design/methodology/approachTo analyse the environmental performance of distribution processes, a model with Visual Basic for Applications (VBA) algorithms compliant with the Global Logistics Emissions Council (GLEC) framework was developed. An integrative review identified key elements for evaluating the environmental impact of distribution processes, leading to model development. The model was validated through a business case in the agri-food supply chain, demonstrating its applicability and enabling the analysis of optimisation scenarios.FindingsThe findings suggest potential savings in CO2e emissions of up to 50% by improving vehicle efficiency and maximising vehicle capacity utilisation. Further savings of up to 30% are highlighted for the business case company by increasing intermodal transport modes use.Originality/valueThis study offers several academic and managerial contributions. On the one hand, it offers a structured approach to assess the environmental performance of the logistics distribution processes based on a comprehensive European standard and enriches the literature by providing an industrial application of GLEC framework guidelines. On the other hand, it empowers logistics practitioners with a model to assess the environmental impact of distribution processes, and it enables an enhanced decision-making process in selecting transport modes to achieve the company’s sustainability goals.
Creative tourism: reviewing the past and charting the future
Authors: Sharma Ishani , Lim Weng Marc , Aggarwal Arun 
Published: January 2025

PurposeWith a growing preference for active, authentic, and cultural experiences over traditional ones, creative tourism has garnered significant academic interest. This study offers a comprehensive review of creative tourism research, delineating its evolution, prominent contributors, pivotal areas, and prospective trajectories through a bibliometric analysis.Design/methodology/approachEmploying a bibliometric analysis using the biblioshiny and VOSviewer software, this study systematically reviews 198 articles on creative tourism identified and retrieved from the Scopus database.FindingsA notable increase in creative tourism research is witnessed in recent times, with Portugal and the Netherlands leading in publications and citations, respectively. This review also pinpoints key authors, countries, institutions, and journals shaping the field, and presents emerging themes such as authenticity and creative experience, culture and heritage, urban and rural contexts, and co-creation in creative tourism.Practical implicationsIdentifying core research contributors (authors, countries, institutions, journals) and contributions (themes, topics) assists academics in seeking collaborations and shaping future research. Practitioners are advised to adapt these trends (authenticity, co-creation, sustainability) into their strategic planning to meet market demands.Originality/valueThis study offers a seminal review of creative tourism through a bibliometric analysis, a technique that leverages the power of technology (data, software) to engage in retrospection and projection—the hallmark of benchmarking studies across fields, including tourism. Noteworthily, this study provides a detailed summary of the field’s trajectory and significant trends, positioning itself as an essential reference for academic scholars, industry professionals, and policymakers with a keen interest in creative tourism.
Research on the resilience path of digitally driven project-based organizations: configuration analysis based on multivalue-set qualitative comparative analysis
Authors: Ma Teng , Zhao Kexin 
Published: January 2025

PurposeThe use of digital technology is crucial for building resilience and shaping competitive advantages in project-based organizations (PBOs). The purpose of this study is to explore the impact of digital elements on organizational resilience and resilience enhancement paths in PBOs represented by the construction industry in the context of digitization.Design/methodology/approachThis study uses multivalue-set qualitative comparative analysis (mvQCA). First, we collect digitization keywords from the annual reports of PBOs in the construction industry and classify them as process digitization, digital technology application and production intelligence while also considering word frequency statistics as antecedent conditions. Second, through a literature review and the use of the data collected, we define organizational resilience as the ability of organizations to defend, resist, recover and develop. Then, we use the mvQCA approach to examine how digital antecedent variables collectively advance PBO resilience.FindingsBy collecting data on 79 listed Chinese construction companies and utilizing mvQCA, we identify five combinations of conditions that produce high levels of organizational resilience, and the solution coverage is 1. These methods are (1) digital technology application-oriented, (2) process digitalization-oriented, (3) digitized multifactor coupling, (4) process digitization and digital technology application-driven and (5) process digitalization and production intelligence-driven.Originality/valueThese findings have important theoretical and practical implications for revealing the digital-driven path to high levels of PBO resilience. In theory, this study enriches the research on organizational resilience and expands the application scope of organizational resilience theory and the QCA method. Furthermore, this study provides new ways and ideas for PBOs to effectively integrate and utilize internal and external digital resources to increase their levels of organizational resilience.
Shielding effectiveness of high-polymer short-staple-based fabric implanted with the metamaterial structure of “split ring resonator”
Authors: Tian Hong , Li Yayun , Xie Xingli , Ye Jindong , Liu Zhe , Wang Xiuchen 
Published: January 2025

PurposeElectromagnetic shielding (EMS) fabrics composed of cotton, polyester and other high-polymer short-staple fibers are widely utilized in various fields. However, the inevitable pores in these fabrics lead to the leakage of electromagnetic waves, which severely diminishes the fabric’s shielding effectiveness (SE). To address this issue, this paper proposes the implantation of a metamaterial structure known as the “split ring resonator (SRR)” into the fabric.Design/methodology/approachFirstly, the types and principles of SRRs are analyzed. Through electromagnetic simulation and emulation, the effectiveness of SRRs in dissipating electromagnetic waves is confirmed. By selecting different embroidery methods, various shapes of SRRs are implanted into the fabric. Subsequently, through testing and analysis of sample fabrics embroidered with SRRs, it is concluded that implanting appropriate SRRs into pure cotton fabrics and cotton/polyester/stainless steel-blended EMS fabrics can effectively impart or enhance the SE of these fabrics.FindingsFor pure cotton fabric without inherent SE, the peak SE value can reach over 30 dB within the 6.57 GHz–7 GHz frequency band, and the minimum SE is greater than 10 dB in the 7 GHz–9.99 GHz frequency band. For the cotton/polyester/stainless steel-blended EMS fabric, the improvement in SE across all frequency bands exceeds 10 dB, averaging around 15.6 dB. The circular type SRR demonstrates the most significant improvement in fabric SE. When the substrate is composed of pure cotton or a cotton/polyester/stainless steel blend, the circular SRRs provide an average enhancement of more than 4 dB and 6 dB, respectively, than other shapes. The fewer the holes created by the implantation method, the higher the SE of the fabric after SRR implantation, with the invisible embroidery technique being the most effective. It improves the fabric’s SE by an average of about 2 dB more than flat embroidery and can be up to an average of around 6 dB higher than the backstitch embroidery technique. For every 0.2 cm increase in the size of the SRRs, the average SE increases by about 4 dB, and for every 0.5 cm increase in the spacing between them, the fabric’s SE decreases by an average of more than 2.7 dB.Originality/valueThis paper offers a novel approach to counteract the issue of pores reducing the SE of EMS fabrics and provides a new method for developing lightweight, thin, low-cost and high-performance EMS fabric composite materials.
What drives trust building in live streaming E-commerce? From an elaboration likelihood model perspective
Authors: Ding Ruolin , Chen Xiayu , Wei Shaobo , Wang Jiawen 
Published: January 2025

PurposeLive streaming e-commerce, which integrates real-time video interaction with online shopping, has quickly become a popular sales channel. It not only allows for immediate feedback but also builds a sense of trust and connection between streamers and consumers. Drawing on the elaboration likelihood model (ELM), we investigate how central and peripheral route factors affect consumers’ trust building and purchase intentions. Additionally, we identify consumer involvement as a key moderator affecting the relationship between central route factors and trust in product as well as the relationship between peripheral route factors and trust in streamer.Design/methodology/approachTo test the research model, we collected data from 423 consumers on TaoBao Live.FindingsThe findings show that information completeness, accuracy and currency positively affect trust in the product, while perceived physical characteristic similarity, streamer humor attractiveness and passion attractiveness positively affect trust in the streamer. Trust in the streamer positively influences trust in the product, which subsequently impacts purchase intention. Moreover, involvement moderates the effects of information accuracy, currency, perceived physical characteristic similarity and passion attractiveness on trust.Originality/valueFirst, we examine the direct influence of product- and streamer-related cues on consumer trust and purchase intention through distinct pathways. Second, we adopt ELM to explain the process of consumer trust building by investigating how central and peripheral route factors influence purchase intention through consumer trust in live streaming settings. Third, we incorporate involvement as a crucial moderator, shedding light on the boundary conditions of trust building in live streaming e-commerce.
Situating sustainable food systems within the international trading regime: what is at stake for developing countries?
Authors: Srivastava Vishakha , Kashyap Ashutosh 
Published: January 2025

Purpose
This paper aims to analyse the concept of the sustainable food system, and discussion on this topic at the international fora. This paper further explores increasing confluence of sustainable food system with international trade. Finally, this paper briefly traces the potential implications of sustainable food systems related obligations for developing countries and least developed countries (LDCs). This paper aims to bring forth the growing confluence of sustainable food system on international trade and potential implications.

Design/methodology/approach
This paper studies the concept of the sustainable food system, growing interlinkage between sustainable food system and international trade through tracing the evolution of discussions related to sustainable food systems at various forums and the potential implications for developing countries.

Findings
This paper shows that there is growing confluence of sustainable food systems with international trade. This paper also highlights the potential implications of the same for developing countries and LDCs. It is difficult, however, to conclusively trace all potential implications.

Originality/value
This paper presents one of the first systematic accounts of the increasing confluence of sustainable food systems and international trade. It shows, at the same time, that developing countries and LDCs need to tread carefully in view of potential implications of the growing confluence of sustainable food systems and international trade.
Taylorism, trade unions and participatory management
Authors: Nyland Chris , Bruce Kyle 
Published: January 2025

Purpose
This study aims to demonstrate that in the latter years of his life, Frederick Winslow Taylor embraced union participation in management decision-making and that interwar US Taylor Society members and organized labor extended his support for this endeavor.

Design/methodology/approach
This study engages with primary materials not previously present in the management history literature and secondary works generated by researchers in disciplines commonly ignored by management scholars.

Findings
This study contests the claim that the scientific managers reached out to unions only after Taylor’s death and demonstrates Taylor welcomed union participation in the management of enterprises, held it was necessary to “show” and not merely “tell” unions that scientific management could be “good” for them, that his inner circle and organized labor jointly promoted these propositions within F.D. Roosevelt’s New Deal administration, and that the US union movement was eventually compelled to settle for a form of industrial relations pluralism that limited their participation to bargaining over the conditions of employment and consequently doomed them to a disastrous future.

Practical implications
This study might support trade unionists develop strategies that may dampen employer hostility and thus revitalize the labor movement and assist management studies rediscover insights that once enabled the discipline to evolve beyond the enterprise. The latter is necessary for this study to live in an age when an increasing number of liberal market economies are characterized by austerity and retrenchment.

Originality/value
This study provides new evidence that demonstrates that Frederick Taylor embraced union participation in enterprise management and also that Taylor Society members actually made a significant contribution to Roosevelt’s New Deal labor policies.