bluuebunny/crossref_metadata_2025_split huggingface dataset:
CARACTERIZAÇÃO HIDROGEOQUÍMICA E DE QUALIDADE DA ÁGUA DE POÇOS TUBULARES EM ALDEIAS INDÍGENAS NA REGIÃO DA AMAZÔNIA CENTRAL
Authors: Andrade Simões Clebsch Consuelo , Aniceto Keila , Wahnfried Ingo Daniel , Tokuta Castro Rodrigo , Lima Leylane , De Souza Lima Rita Mileni , Souza de Oliveira Tereza Cristina 
Published: February 2024

Apesar da abundância de água superficial na região amazônica, sua população utiliza predominantemente o recurso subterrâneo. No Amazonas, as águas subterrâneas são única fonte de água em 71% das sedes municipais. Das 276 aldeias cadastradas no Distrito Sanitário Especial Indígena de Manaus (DSEI-MAO) até 2022, 7,6% possuem sistemas de abastecimento de água provenientes de poços profundos. Com o objetivo de avaliar os padrões de qualidade de água preconizados pela legislação brasileira vigente, este estudo apresenta resultados obtidos a partir das águas de três poços tubulares localizados em áreas rurais autodenominadas como indígenas. Foram realizadas análises de pH, Condutividade Elétrica (CE), Sólidos Totais Dissolvidos (STD), elementos maiores Ca2+, Mg2+, Na+, K+ F-, Cl-, NO2-, Br-, NO3-, PO43- e SO42- e traços Al, As, Ba, Cd, Pb, Cu, Cr, Ni e Zn e coliformes totais e Escherichia coli. Os valores de pH (5,4-6,6) e CE (18,1-106 µS.cm-1) encontrados estão dentro das faixas observadas em estudos anteriores. Os resultados analíticos dos períodos sazonais são típicos de águas fracamente mineralizadas, com variação na classificação química de potássica sulfetada para cálcica cloretada em um dos poços. A sequência de abundância dos cátions é K>Ca>>Na>Mg, com o K+ apresentando concentrações maiores que os demais cátions (até 5,1 mg.L-1), o que é incomum devido à sua baixa mobilidade geoquímica. Por outro lado, as concentrações de SO42- são mais elevadas do que em estudos anteriores (até 9,8 mg.L-1). De modo geral, as águas mostram-se próprias para o consumo humano e não apresentam indícios de contaminantes.
CARACTERIZAÇÃO MULTITEMPORAL DE BARRAS FLUVIAIS NO ARQUIPÉLAGO DE MARIUÁ, MÉDIO RIO NEGRO , AMAZONAS
Authors: Jesus de Souza Jefferson , Alberto Amaral Soares Emílio , Hatsue Tatumi Sonia , Raimundo Pantoja Tarabossi Ricieri , Yee Márcio , Dino Rodolfo , Antonioli Luzia , Leite Dias Fábio 
Published: February 2024

Este trabalho apresenta a evolução morfológica de barras arenosas da porção oeste do Arquipélago de Mariuá, médio curso do Rio Negro. Apesar desse arquipélago ser considerado o maior do planeta, estudos referentes à última fase de sedimentação das ilhas e barras ainda são escassos, principalmente relacionados aos processos de erosão e sedimentação. Foram utilizadas ferramentas de sensoriamento remoto, através da análise multitemporal de imagens Landsat, para o entendimento da evolução morfológica das barras arenosas no intervalo temporal de 31 anos (1985 - 1997 - 2016). No primeiro período (1985 - 1997) a taxa de erosão foi maior que a deposição, enquanto no segundo período (1997 - 2016) predominou a dinâmica deposicional acrescionária, ambas relacionadas a variação do aporte sedimentar. Com base nos resultados obtidos, o aumento ou a diminuição do aporte sedimentar foi relacionado com as mudanças morfológicas das barras arenosas, bem como aos períodos de maior e menor precipitação, que refletem as características dos fenômenos El Nino e La Nina na Amazônia. Particularmente, foi possível evidenciar a relação do aumento no aporte sedimentar, indicado pelos dados da carga de sedimentos em suspensão (CSS), descarga sólida e análise multitemporal das barras, com o fenômeno La Nina, que influenciou no aumento na taxa de precipitação na Bacia do Rio Negro. Apesar da análise multitemporal das barras no arquipélago envolverem um intervalo de tempo recente e curto (31 anos), o resultado pontual de datação por Luminescência Opticamente Estimulada (LOE) indica que a sedimentação das barras iniciou há pelo menos cinco (05) séculos.
Quantification of Total Phosphorus Content in Plant Material Using Microwave Digestion and Segmented Flow Analysis
Authors: Cain Sophia , Younes Nicolas , Buss Wolfram , Latimer James 
Published: February 2024

Abstract
This protocol aims to quantify the total phosphorus (P) concentration in leaf material through acid digestion and segmented flow analysis. This method has been tested on plant species including Australian Eucalyptus and other native understory species but could be applicable to foliar leaf material in general with minor modifications. Phosphorus content is often measured using a Kjeldahl digestion, which can be time consuming; we present this microwave digestion method using nitric acid and hydrogen peroxide as an alternative to reduce sample digestion times. This method is limited by the number of positions available in the microwave digestion rotor. Phases of analysis include: (1) acid digestion using microwave digestor (3 hours); (2) preparation of reagents (2 hours); and, (3) analysis for total P on the flow analyser using antimony-phospho-molybdate complexation reaction (30 minutes plus 90 seconds per sample).
The effect of seasonal variation on the antibacterial activity of Tithonia diversifolia (Hemsl.) A. Gray leaf extracts against pathogenic bacterial strains
Authors: Folagboye Emmanuel Ayotunde , Adewole Moses Bamidele , Abimbola Olufemi Gabriel , Adewumi Sanjo Samson , Okafor Chimezie Alphonsus , Adeyemo Stella Mojisola 
Published: February 2024

Abstract
The study investigates the antibacterial activity of Tithonia diversifolia leaves, including methanol, ethanol and water extracts, against Pseudomonas aeruginosa, Klebsiella pneumoniae, Serratia marcescens, Proteus vulgaris, Micrococcus luteus, Staphylococcus aureus, Bacillus subtilis, Clostridium sporogenes using the agar well diffusion technique. Minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) were performed on bacteria by a modification of the standard agar dilution method. Qualitative phytochemical analysis of leaf extract was determined by standard analytic methods. The study found that Klebsiella pneumoniae and Bacillus subtilis showed less susceptibility to water extracts, while Pseudomonas aeruginosa and Proteus vulgaris were sensitive to all water extract samples with zone of inhibition of 20.5 mm and 20.0 mm, respectively. However, all methanol extracts were susceptible to Pseudomonas aeruginosa, Proteus vulgaris, and Staphylococcus aureus with zones of inhibition of 18.0, 14.0, and 15.0 mm, respectively. Serratia marcescens showed less susceptibility to most methanol extracts, while Clostridium sporogenes showed susceptibility to all ethanol extracts. MICs and MBC values against bacterial strains ranged from 12 - 50 mgmL-1 and 25 - 100 mgmL-1 respectively. The study concluded that the leaves of Tithonia diversifolia contain phytochemicals with broad-spectrum antimicrobial effects, with ethanol extracts showing high sensitivity. The concentration of these phytochemicals varies by season, with higher levels observed during rainy seasons. The study highlights the potential of Tithonia diversifolia leaves for antimicrobial properties.
Uncertainty-Aware Graph Neural Network for Semi-Supervised Diversified Recommendation
Authors: Minjie  
Published: February 2024

Abstract
Graphs are a powerful tool for representing structured and relational data in various domains, including social networks, knowledge graphs, and molecular structures. Semi-supervised learning on graphs has emerged as a promising approach to address real-world challenges and applications. In this paper, we propose an uncertainty-aware pseudo-label selection framework for promoting diversity learning in recommendation systems. Our approach harnesses the power of semi-supervised Graph Neural Networks (GNNs), utilizing both labeled and unlabeled data, to address data sparsity issues often encountered in real-world recommendation scenarios. Pseudo-labeling, a prevalent semi-supervised method, combats label scarcity by enhancing the training set with high-confidence pseudolabels for unlabeled nodes, enabling self-training cycles for supervised models. By incorporating pseudo-labels selected based on the model’s uncertainty, our framework is designed to improve the model’s generalization and foster diverse recommendations. The main contributions of this paper include introducing the uncertainty-aware pseudo-label selection framework, providing a comprehensive description of the framework, and presenting an experimental evaluation comparing its performance against baseline methods in terms of recommendation quality and diversity. Our proposed method demonstrates the effectiveness of uncertainty-aware pseudo-label selection in enhancing the diversity of recommendation systems and delivering a more engaging, personalized, and diverse set of suggestions for users.
TopoFormer: Multiscale Topology-enabled Structure-to-Sequence Transformer for Protein-Ligand Interaction Predictions
Authors: Wei Guo-Wei , Chen Dong , Liu Jian 
Published: February 2024

Abstract

Pre-trained deep Transformers have had tremendous success in a wide variety of disciplines. However, in computational biology, essentially all Transformers are built upon the biological sequences, which ignores vital stereochemical information and may result in crucial errors in downstream predictions. On the other hand, three-dimensional (3D) molecular structures are incompatible with the sequential architecture of Transformer and natural language processing (NLP) models in general. This work addresses this foundational challenge by a topological Transformer (TopoFormer). TopoFormer is built by integrating NLP and a multiscale topology techniques, the persistent topological hyperdigraph Laplacian (PTHL), which systematically converts intricate 3D protein-ligand complexes at various spatial scales into a NLP-admissible sequence of topological invariants and homotopic shapes. Element-specific PTHLs are further developed to embed crucial physical, chemical, and biological interactions into topological sequences. TopoFormer surges ahead of conventional algorithms and recent deep learning variants and gives rise to exemplary scoring accuracy and superior performance in ranking, docking, and screening tasks in a number of benchmark datasets. The proposed topological sequences can be extracted from all kinds of structural data in data science to facilitate various NLP models, heralding a new era in AI-driven discovery.
The Burden and Opportunities for Screening NCDs among People Living With HIV/AIDS Attending Care and Treatment Clinic at Temeke Regional Referral Hospital in Dar es Salaam
Authors: Musyani Atuganile , Mosi¹ Grace , Kinyenje¹ Erik , Mizinduko Mucho , Kishimba¹ Rogath , Shimwela Meshack , Leonard Subi 
Published: February 2024

Abstract

Introduction:
People living with HIV (PLHIV) in Tanzania now live longer and hence are at increased risk of developing non-communicable diseases (NCDs). Despite the substantial resources available for HIV care programs, the effective integration of NCD care into these programs remains inadequate. This study aimed to describe the risk factors for NCDs and evaluate the control rates of three-month NCD preventive efforts among PLHIV attending the Care and Treatment Clinic (CTC) at Temeke Regional Referral Hospital (RRH).
Materials and methods
This was a mixed methods study in which a cross-sectional approach was utilized to identify hypertension risk factors among PLHIV attending Temeke RRH in January 2020 and pre- and postintervention follow-ups were used to assess NCD control rates from February to April 2020. The survey included interviews, secondary data review, and blood pressure and glucose screening using the STEPwise approach of the World Health Organization (WHO) STEPS surveillance tool for NCDs. Data analysis was performed using the STATA tool, employing logistic regression to ascertain risk factors. Patients diagnosed with hypertension, increased blood glucose, or both were enrolled in an intervention program to receive NCD-related preventive health education. Blood pressure and blood glucose levels were re-evaluated at the end of the intervention. Control rates were assessed using paired t tests.
Results:
A total of 333 PLHIV were interviewed; 71 (21.32%) were diagnosed with hypertension, and 2.70% had high blood sugar levels. Among the total interviewees, 177 (53.15%) had never had their blood pressure (BP) measured before, and among them, 37 (20.90%) were diagnosed with hypertension. Within the cohort group of 76 patients, 71 had hypertension, 26 (36.6%) of whom were effectively controlled at the end of the intervention. Among the 9 PLHIV with high blood glucose levels, 5 (55.5%) achieved a normal blood sugar level.
Conclusion:
The burden of undiagnosed NCDs among PLHIV attending the care and treatment clinic at Temeke RRH is notably high. Interventions aimed at addressing these NCDs appear to be effective
Sero-prevalence of peste des petits ruminants virus-specific antibodies in Sudanese sheep and goats before and after vaccination
Authors: Algezoli Omer , Kamal Selma , Raouf Yazeed , Alamin Muzdalifa , Ali Hiba , Aljameel Mohamed , Ahmed Sulieman , Mohamed Sir Elkhatim , Elsied Ibtesam Fadul , Nour Tajeldin , Abdalla Mohamed 
Published: February 2024

Abstract

Peste des petits ruminants virus (PPRV) antibodies were studied in Sudanese sheep and goats (n = 855) before and after vaccination with a locally produced Nigeria 75/1 vaccine using a commercial competitive ELISA (cELISA) kit (IDvet Grabels). Animals were kept healthy under field conditions, in four states; Blue Nile (n = 250), North Kordofan (n = 189), South Darfur (n = 225) and the Northern State (n = 191). Before vaccination, sero-prevalence of PPRV antibodies was 54.6% (53.2%-56% 95% CI); high (64.8%-76.4% 95% CI) in South Eastern Sudan (Blue Nile), medium (50.5%-61.9% 95% CI) in Western Sudan (North Kordofan and South Darfur) and low (28.6%-35.2% 95% C.I) in Northern Sudan (Northern State). In high-risk areas (high sero-prevalence), Blue Nile (70.4%) and North Kordofan (57.7%), middle age groups (7–12 and 13–18 months) were identified as high-risk age. Middle age groups showed lower sero-prevalence than preceding (3–6 months) and subsequent (> 18 months) age groups while the risk of exposure increased with age. Current and previous findings suggested a transmission pathway of PPRV involving the South Eastern border (Blue Nile) and neighbouring Central Sudan to North Kordofan. One month after vaccination 88.4% (343/388) of sero-negative animals were sero-converted suggesting the efficacy of the locally produced Nigeria 75/1 vaccine. Had only the high- risk age group (7–18 months) was vaccinated, the overall population immunity (OPI) in high-risk areas (Blue Nile and North Kordofan) would have surpassed the threshold of 70% indicated for blocking PPRV transmission. However, lower vaccination coverage is expected in wider vaccination programme. findings justified targeting PPR control in Sudan, primarily, by vaccination of high-risk age groups in high-risk areas.
Effect of catalyst type on the structure, mechanism and thermal properties of melamine-formaldehyde resins
Authors: Sun Yumiao , Wang Ting , Zeng En 
Published: February 2024

Abstract

The uncertainty of the structure of melamine-formaldehye polymer is one of the important factors limiting its widespread application. The chemical reactions of melamine are almost always reversible, so controlling the microstructure is difficult. For the synthesis of polymer particles in water, it is unclear how the type of catalyst affects the microstructure of melamine-formaldehye polymers. Therefore, we conducted a detailed study to understand how different catalyst types( including 10% NaOH, trimethylamine,and a Na2CO3-NaHCO3 buffersolution)affect the hydroxymethylation reaction, structure and the thermal properties of the melamine-formaldehye polymer). The results showed that with the same molar ratio and pH conditions, the use of triethylamine as catalyst in the melamine-formaldehye polymer increased the possibility of side reactions in the hydroxymethylation reaction. However, the occurrence of side reactions has a favorable effect on the thermal properties of melamine-formaldehyepolymers. Specifically, melamine formaldehyde polymers synthesized using triethylamine as a catalyst exhibit higher thermal decomposition characteristic temperatures, lower kinetic values, and higher reactivity. These results provide insights into the effect of catalyst type on the reaction mechanism, microstructure and thermal properties of melamine-formaldehye polymers, which may prove useful for their improved and controlled synthesis.
Coding and non-coding variants in the ciliopathy gene CFAP410 cause early-onset non-syndromic retinal degeneration.
Authors: Bujakowska Kinga , Sangermano Riccardo , Gupta Priya , Price Cherrell , Han Jinu , Navarro Julien , Condroyer Christel , Place Emily , Antonio Aline , Mukai Shizuo , Zanlonghi Xavier , Sahel José-Alain , Duncan Jacque , Pierce Eric , Zeitz Christina , Audo Isabelle , Huckfeldt Rachel 
Published: February 2024

Abstract

Inherited retinal degenerations are blinding genetic disorders characterized by high genetic and phenotypic heterogeneity. The implementation of next-generation sequencing in routine diagnostics, together with advanced clinical phenotyping including multimodal retinal imaging, have contributed to the increase of reports describing novel genotype-phenotype associations and phenotypic expansions. In this study, we describe sixteen families with early-onset non-syndromic retinal degenerations in which affected probands carried rare bi-allelic variants in CFAP410, a ciliary gene previously associated with syndromic recessive Jeune syndrome. The most common retinal phenotypes were cone-rod and rod-cone dystrophies, but the clinical presentations were unified by their early onset as well as the severe impact on central visual function. Twelve variants were detected (three pathogenic, seven likely pathogenic, two of uncertain significance), eight of which were novel. One deep intronic change, c.373+91A>G, led to the creation of a cryptic splice acceptor site in intron four, followed by the inclusion of a 200-base pair pseudoexon and subsequent premature stop codon formation. To our knowledge this is the first likely pathogenic deep-intronic variant identified in this gene. Meta-analysis of all published and novel CFAP410 variants revealed no clear correlation between the severity of the CFAP410-associated phenotypes and the identified causal variants. This is supported by the fact that the frequently encountered missense variant p.(Arg73Pro), often found in syndromic cases, was also associated with non-syndromic retinal degeneration. This study expands the current knowledge of CFAP410-associated ciliopathy by enriching its mutational landscape and supports its association with non-syndromic retinal degeneration.
Extraction method for edge artifact features of Si3N4 bearing roller microcracks based on two-dimensional discrete wavelet transform and Otsu threshold segmentation
Authors: Chen Tao , Xia Xin , Zhou Jianbin , Zhang Yixiang , Wang Xiang , Wu Nanxing 
Published: February 2024

Abstract

Aiming at the problem that the edge artifacts of Si3N4 bearing roller microcracks have low contrast, contain noise, and easily merge with the background, making it difficult to segment. Design a method based on a two-dimensional discrete wavelet transform and Otsu threshold segmentation. Realize the extraction of edge artifact features of Si3N4 bearing roller microcracks. Wavelet decomposition is used to remove noise, while wavelet reconstruction features are used to restore lost details. Create a discrete wavelet transform function equation in two dimensions that includes wavelet reconstruction and wavelet decomposition. Achieve contrast improvement and noise removal in edge artifact feature images. Aiming at the problem of artifacts existing at the edge of defects in images that are difficult to remove using conventional methods. A threshold segmentation function equation with the core idea of maximizing inter class variance is designed. Finish choosing the ideal threshold. In order to accomplish the goal of eliminating the edge artifact feature. The average PSNR of the image enhanced by point, line, and surface micro crack edge artifact features of the Si3N4 bearing roller is close to 62.69dB. The average SSIM is about 0.77. Increases the contrast of Si3N4 bearing roller microcrack edge artifact features in an efficient manner. Improved the effect of feature extraction of point, line, and surface micro crack edge artifacts in Si3N4 bearing rollers.
Estimating the Cost of Basic Public Health Service in Township Health Centers in Guangxi province, China: Based on Equivalence method
Authors: Wang shuyun , Zhao Yilin , Liang Xia , Kang Jing , Chen Yujun , Zhao Huihan , Lin Lin , Zhang Ying , Huang Zhaoquan , Feng Qiming 
Published: February 2024

Abstract
Objectives
By measuring the cost of basic public health service projects in township health centres in Guangxi, it provides a reference for improving the practical test of the theoretical system of the equivalence method, saving the cost of the projects, and improving the efficiency and quality of the services provided by medical personnel.
Methods
We used a multi-stage stratified sampling method to select 50 township health centres from Guangxi province, China. The cost of the basic public health service projects was measured by the equivalent method through field research and data collection.
Results
In 2020, 50 township health centres in Guangxi carried out 71 primary medical care services in 5 major categories and 37 basic public health services in 13 major categories, with a total cost of RMB 492,818,700. The equivalent cost of a standard service was RMB 18.00, and the per capital cost of the basic public health service items was RMB 110.95.
Conclusion
The equivalent method is applicable to township health centres; the financial subsidy of the basic public health service items is lower than the measured standard cost; there are differences in the project cost in different regions, which are mainly affected by the financial funds allocated by the local government and the efficiency of the services provided by grassroots medical staff. There is a need to improve the arrival rate of financial funds and the standardisation of services provided by grassroots medical staff.
Radiofrequency in the Treatment of Urinary Incontinence of Female Stress: A Pilot Randomized Clinical Trial
Authors: Brasil Cristina , Sodré Danielle , Lemos Amanda , Coutinho João , Vieira Mauricio , Mamede Tuffy , Teles Alcina , Lordelo Patricia 
Published: February 2024

Abstract

Radiofrequency (RF) is a new therapeutic option that may aid one of the pathophysiological mechanisms of stress urinary incontinence (SUI), which is a decrease in collagen in the urethral walls. This study aimed to verify the clinical response to nonablative RF treatment for SUI in women. This randomized clinical trial included women with SUI, randomized into two groups: the RF group (RG), which had five sessions of outpatient kinesiotherapy associated with monopolar nonablative RF, in the external urethral meatus (39–41°C) for 2 min, and the control group (CG), which followed the same protocol, except the RF was replaced with heated glycerin. All participants performed home exercises. Outcomes were assessed one week after treatment completion. The RG and CG had 13 and 9 women, respectively. The median reduced from 7.0 (4.5–14.5) to 1.0 (0.0–4.0) in the RG. In addition, a reduction in urinary loss was observed through a voiding diary, an increase in strength, endurance, resistance, and speed of the PERFECT scheme. There was a reduction in urinary loss in grams in women who underwent nonablative RF in the external urethral meatus.