bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economic globalization and ecological impact in emerging economies in the post‐COP21 agreement: A panel econometrics approach
Authors: Bekun Festus Victor , Ozturk Ilhan 
Published: February 2024

AbstractGlobally, the need for ecological well‐being and sustainable development attracted research and policy attention over the years. However, issues concerning the nexus between globalization and ecological safety remain contentious and unresolved. Therefore, this study contributes to the discourse by evaluating the impact of economic globalization on ecological footprints in seven emerging economies (E7) while accounting for other drivers of environmental degradation in the outlined bloc for the period of 1990–2021. The present study leverages on panel data econometric techniques to achieve the study objectives. The findings shows that economic globalization and increase in economic activities drive a higher ecological footprint and thus reduce environmental quality in emerging economies. This study concludes that the economic progress of emerging economies and the increasing wave of their economic integration is detrimental to environmentally sustainable development. Therefore, this study recommends, among other insightful policy inferences, that the global agenda on sustainable development should be prioritized, environment‐friendly integration among emerging economies should be pursued. Environmental regulations should be strictly observed by the countries in their bid for economic development and integration.
Fat embolism syndrome associated with atraumatic compartment syndrome of the bilateral upper extremities: An unreported etiology
Authors: Ali Zabiullah , Troncoso Juan C. , Redding‐Ochoa Javier 
Published: February 2024

AbstractFat embolism syndrome (FES) is a potentially life‐threatening condition that develops when fat embolism leads to clinical symptoms and multisystem dysfunction. The classic triad of respiratory distress, neurologic symptoms, and petechial rash are non‐specific, and the lack of specific laboratory tests makes the diagnosis of FES difficult. Although FES is most common after long bone fractures, multiple conditions some of which are atraumatic have been associated with the development of FES. We report a case of FES that occurred in the setting of a non‐traumatic compartment syndrome of the upper extremities. The pathologic and clinical findings, pathophysiology, diagnostic challenges, and pathologic methods to properly diagnose FES are discussed with a review of the relevant literature. This case highlights the importance of the autopsy in making a diagnosis of FES in cases where death could otherwise be incorrectly attributed to multi‐organ system failure, shock, or sepsis.
Remarkable response to pazopanib plus vivolumab in a patient with pericardial synovial sarcoma carrying a novel genotype BRCA2 c.968dupT: A case report
Authors: Zhang Xing , Xu Qinqin , Zhang Yongchang 
Published: February 2024

AbstractPericardial synovial sarcomas (PSS) have a low incidence rate and are highly invasive with a dismal prognosis. Standard treatment includes surgery, radiotherapy and chemotherapy but with limited response. Here, we report the case of a 15‐year‐old nonsmoking youngster diagnosed with PSS who developed disease relapsed from surgery after 1 month. Next‐generation sequencing (NGS) using baseline tissue was performed, and BRCA2 c.968dupT was detected. Then pazopanib (a multitargeted inhibitor) plus nivolumab (an immune checkpoint inhibitor) was administered, with a partial response and progression‐free survival of 14 months. BRCA2 c.968dupT has not previously been reported in PSS and its response to targeted combination immunotherapy are not well characterized. Here, we report the efficacy of pazopanib combined with nivolumab in a PSS patient harboring BRCA2 c.968dupT and also provide the clinical evidence of the utility of NGS in exploring actionable mutations for solid tumor. Combination therapy based on immunotherapy may be a potential treatment choice for PSS harboring BRCA2 mutation.
A multistate transition model of changes in loneliness and carer stress among community‐dwelling older adults in Aotearoa New Zealand
Authors: Abey‐Nesbit Rebecca , Bergler Hans Ulrich , Keeling Sally , Gillon Deb , Bullmore Irihapeti , Schluter Philip J. , Jamieson Hamish 
Published: February 2024

AbstractObjectivesTo identify changes in loneliness and carer stress between two time points for older people of different ethnicities who had repeated interRAI home care assessments.MethodsParticipants consisted of community‐dwelling older adults across New Zealand who received two interRAI‐HC assessments between 5 July 2012 and 31 December 2019. Two multistate models were developed: the first model was not lonely versus lonely, and the second model was no carer stress versus carer stress. The one‐year transition probabilities were calculated. Mean sojourn times were calculated for each state except death. Paired t‐tests assessed the differences in transition probabilities between the different ethnic groups.ResultsThe mean age of the cohort was 82.5 years (SD 7.7 years). At first assessment, 14,646 (21%) older people stated they were lonely and 26,789 carers (38%) experienced stress. The most common first transition type was not lonely to not lonely: Māori 42%, Pacific 54%, Asian, 48% and Other 40%. The highest one‐year transition probability in the loneliness model was living in aged residential care to death (0.79). The most common first transition type for the carer stress was no carer stress to no carer stress: Māori 35%, Pacific, 46%, Asian, 43% and Other 33%. The highest one‐year transition probability in the carer stress model was living in aged residential care to death (0.80). The statuses not lonely and no carer stress had a mean sojourn time of approximately one year, and eight months to one year, respectively.ConclusionsLoneliness can change over time due to circumstances and an individual's perception of loneliness at the time of assessment. Carer stress is enduring and has a low probability of improvement.
Negative Performance Aspiration Gap and Stock Price Crashes: Based on Behavioral Theory and Agency Theory Perspective*
Authors: Wang Mengsha 
Published: February 2024

AbstractThe paper explores how agency behavior of insiders within a company influences the risk of a stock price crash in the context of a continued expansion of the performance expectation gap. A panel data analysis of 10 727 observations of Chinese A‐share listed companies over the period 2003–2020 shows that as the negative performance aspiration gap widens, stock price crashes are more likely to occur. Furthermore, the separated role of top management and chairperson and an increase in the ownership proportion of major shareholders significantly amplifies the positive effect, whereas the increase in managerial shareholding and the equity balance diminish the main relationship.
Older adults experience better affective well‐being in solitude: The moderating role of goal for conflict de‐escalation
Authors: Jiang Da , Lay Jennifer C. , Fung Helene H. 
Published: February 2024

AbstractOlder adults report greater affective well‐being in solitude than younger adults, but prior findings are based on correlational designs. We aim to examine age differences in affective well‐being in solitude using an experimental design and to examine conflict de‐escalation as a potential mechanism. In Study 1, 207 participants were randomly assigned to either a solitude or a social interaction condition. In Study 2, 128 participants were randomly assigned to one of four conditions: solitude‐escalation, solitude‐de‐escalation, interaction‐escalation, and interaction de‐escalation. After a 15‐min solitude or social interaction period, they reported their affective experiences. In Study 1, older (vs. younger) adults reported more positive affect overall. This age‐related difference was greater in the solitude (vs. social interaction) condition; older adults reported less negative affect than younger adults in the solitude, but not the social interaction, condition. In Study 2, older (vs. younger) participants reported more high‐arousal positive affect in the solitude‐escalation condition. This difference was not significant in conflict de‐escalation conditions. Our studies provide causal evidence of the relationship between solitude and affective well‐being and advance our understanding of motivations that explain why older adults maintain better affective well‐being in solitude.
Earliest known well‐preserved flour comestibles unearthed in the Wupu Cemetery in Hami, Xinjiang, China
Authors: Wang Lijing , Ge Yong , Wang Yongqiang , Zhang Guilin , Wang Binghua , Jiang Hongen 
Published: February 2024

AbstractExploring the utilisation of flour in ancient Xinjiang is crucial for understanding the use of different grain crops as staple comestibles. In this study, multiple analyses were applied to identify five flour food remnants discovered in the Wupu Cemetery (1100–400 BCE) in Hami, Xinjiang. Results show that two of the samples were comprised of broomcorn millet (Panicum miliaceum) mixed with wheat (Triticum aestivum) and barley (Hordeum spp.), one of wheat and barley, and the remaining two primarily of broomcorn millet with a low quantity of foxtail millet (Setaria italica). Plant microfossils analysis and microscopic observation of cross‐sections of the five samples indicate that these crop materials were coarsely ground into flour and then probably baked without fermentation. These findings provide the earliest evidence that broomcorn millet, wheat, and barley were processed as cakes in Hami 3000 years ago. Moreover, the findings in this study also emphasise the reassessment of the role of foxtail millet in the dietary consumption of the ancient Wupu inhabitants, as foxtail millet was abundant in tombs, but scarce in comestible food sources. This research sheds light on and contributes to a more precise reconstruction of the dietary patterns of ancient indigenous people in Hami.
Rumen degradable protein levels on fatty acid profile of rumen bacteria and milk fat of dairy cows supplemented with calcium salts of fatty acids
Authors: Del Valle Tiago Antônio , de Castro Zilio Elissandra Maiara , Ghizzi Lucas Ghedin , Marques Julia Avansi , Sakamoro Lucas Yudi , Sconamiglio Nathalia Trevisan , da Silva Dias Mauro Sérgio , de Paula Silva Tássia Barrera , Nunes Alanne Tenório , Silva Guilherme Gomes da , Gheller Larissa Schneider , Rennó Francisco Palma 
Published: February 2024

AbstractThis study aimed to evaluate the effects of calcium salts of fatty acids (CSFA) from soybean oil in diets with different levels of rumen degradable protein (RDP) on bio‐hydrogenation extent, and fatty acid (FA) profile intake, omasal digesta, rumen bacteria, and milk fat. Eight Holstein lactating cows were used in a replicated 4 × 4 Latin square design. Treatments were arranged in a 2 × 2 factorial design with two CSFA levels (0 or 33.2 g/kg DM of CSFA) and two RDP levels (98.0 or 110 g/kg DM). There was RDP and CSFA interaction effect on the omasal flow of total FA and some specific FA. Only in −CSFA diets, the higher RDP level increased omasal flow of total FA. Dietary RDP levels did not affect the FA profile of bacteria and milk fat. Feeding CSFA reduced or tended to reduce the bacterial proportion of C15:0, C16:0, C16:1, C17:0, and C18:0 FA and decreased the concentrations of short‐ and medium‐chain FA (<18C) and increased the concentrations of unsaturated and long‐chain FA (≥18C) in milk fat. Feeding CSFA of soybean oil increases the intake and omasal flow of FA and augments unsaturated FA content in bacteria pellets and milk fat.
Physicochemical properties as indicators of sensory characteristics of jidori and broiler chicken meat
Authors: Yoshida Yuri , Honma Fumika , Obana Naoaki , Matsumoto Kazunori , Nishimura Takanori , Irie Masakazu 
Published: February 2024

AbstractTo improve the eating quality of chicken, the physicochemical properties were examined, which serve as indicators for breeding. Thigh meat was collected from 384 chickens from seven and nine types of the jidori (free‐range local traditional pedigree chickens) or broiler chickens, respectively. The principal component analysis of the physicochemical values of the jidori and broilers were arranged as different groups in the score plot. The results of multiple regression analysis of the sensory characteristics and physicochemical properties of thigh meat indicated that the tenderness decreased with the higher crude protein content and cooking loss in the jidori and increased with lower cooking loss and higher moisture and ether extract content in the broiler. The juiciness of the jidori decreased as the moisture content decreased, and that of the broiler decreased as the cooking loss and crude protein content increased. The umami of both the jidori and broiler was improved by increasing the 5′‐inosinic acid content. Therefore, it was suggested that the physicochemical properties, which serve as indicators of the eating quality of chicken, differed between the jidori and broiler, and that the general biochemical components, cooking loss and 5′‐inosinic acid content may serve as breeding indicators.
Population pharmacokinetics and dose optimization of levofloxacin in elderly patients with pneumonia
Authors: He Yun‐Ying , Sun Jing , Wu Yue‐E , Wang Yong‐Bin , van den Anker John , Hao Guo‐Xiang , Sun De‐Qing , Zhao Wei 
Published: February 2024

AimsLevofloxacin is a quinolone antibiotic with a broad antibacterial spectrum. It is frequently used in elderly patients with pneumonia. The pharmacokinetic profile of elderly patients changes with age, but data on the pharmacokinetics of levofloxacin in these patients are limited. The aim of this study was to establish a population pharmacokinetic model of levofloxacin in elderly patients with pneumonia and to optimize individualized dosing regimens based on this newly developed model.MethodsThis is a prospective, open‐label pharmacokinetic study in elderly patients with pneumonia. Blood samples were collected using an opportunistic approach. The plasma concentrations of levofloxacin were determined by high‐performance liquid chromatography. A population pharmacokinetic model was established using nonlinear mixed‐effect model software. Monte Carlo simulations were used for dose simulation and dose optimization.ResultsData from 51 elderly patients with pneumonia were used for the population pharmacokinetic analysis. A one‐compartment model with first‐order elimination was most suitable for describing the data, and the estimated glomerular filtration rate was the only covariate that had a significant impact on the model. The final model estimated that the mean clearance of levofloxacin in elderly patients with pneumonia was 5.26 L/h. Monte Carlo simulation results showed that the optimal dosing regimen for levofloxacin was 750 mg once a day in elderly patients with pneumonia, with a minimum inhibitory concentration of 2 mg/L.ConclusionsThe population pharmacokinetic model of levofloxacin in elderly patients with pneumonia was established, and the dose optimization of levofloxacin was completed through Monte Carlo simulation.
Team ethical culture as a coupling mechanism between a well‐implemented organizational ethics program and the prevention of unethical behavior in teams
Authors: Cabana Guillem C. , Kaptein Muel 
Published: February 2024

AbstractMany organizations have adopted an organizational ethics program to prevent unethical behavior within the organization. Decoupling the adoption of ethics programs from their implementation has been identified in the literature as an explanation for the ineffectiveness of such programs. In addition to this so‐called policy–practice decoupling, means–ends decoupling may also occur when a well‐implemented ethics program is nevertheless ineffective. This study investigates whether team ethical culture (TEC) acts as a coupling mechanism that mediates the effects of a well‐implemented ethics program on unethical behavior in teams. We conducted a survey of 202 teams working in a business organization in the UK. The results of a structural equation analysis support the claim that TEC mediates this relationship. Based on this team‐level case study, we argue that organizations that aim to implement an effective ethics program should acknowledge and manage TECs to avoid means‐ends decoupling.
Identifying predictors of a favourable outcome for outpatients with a persistent depressive disorder treated with Cognitive Behavioural Analysis System of Psychotherapy: A prospective cohort study
Authors: Dean Juliana A. , Eldering Marieke J. , Schoevers Robert A. , van Driel Catheleine M. G. 
Published: February 2024

AbstractObjectivesCognitive Behavioural Analysis System of Psychotherapy (CBASP) is the first therapy specifically developed for persistent depressive disorder (PDD). This study aimed to identify predictors of favourable treatment outcome after group CBASP and assess change in depression severity over 24 weeks.DesignA prospective cohort study was conducted in patients with PDD treated with group‐CBASP.MethodsOutcomes were depression severity measured by the Inventory of Depression Severity—self‐report (IDS‐SR) after 6 and 12 months. Potential predictors investigated were baseline depression severity, prior antidepressant use, age, family status, income source, age of onset and childhood trauma. Multivariate logistic regression was performed to assess their effects with a ≥25% IDS‐SR score decrease as the dependent variable.ResultsThe IDS‐SR score (range 0–84) significantly decreased from 37.78 at start to 33.45 at 6 months, an improvement which was maintained at 12 months. Having paid work and no axis I comorbidity significantly predicted favourable response. In the groups without a favourable outcome predictor a substantial percentage still showed at least partial response (16.7% and 19.2%).ConclusionsSource of income and axis I comorbidity were predictors of response to group‐CBASP. Within the group without favourable outcome predictors, a subgroup showed at least partial response. These results suggest that group‐CBASP has promise for patients who do not respond to standard treatments. Future studies should include outcome measures that take into account comorbidity and other clinically relevant changes, such as social functioning.
Being pressed for time leads to treating others as things: Exploring the relationships among time scarcity, agentic and communal orientation and objectification
Authors: Jiang Xinying , Zhang Nan , Sun Xiaomin , Liu Zhenzhen , Wang Yuqiao Lilly 
Published: February 2024

AbstractTime scarcity has become one of the most ubiquitous phenomena in daily life worldwide. Five studies (total valid N = 1332) examined whether time scarcity elicits people's agentic orientation and dampens their communal orientation, thus increasing the likelihood of objectification towards others. Results suggested that people who perceived time scarcity were more likely to exhibit objectification towards others regardless of whether time scarcity was measured (Studies 1 and 3) or manipulated using either a scenario (Study 2a) or a recall task (Studies 2b and 4). Furthermore, agentic and communal orientations mediated the link between time scarcity and objectification (Studies 3 and 4). Additionally, the current research provided a nuanced understanding of these effects by differentiating the people being objectified into acquaintances and close friends (Study 2b) and by taking into consideration the trait‐level prosociality of participants (Study 4). Results suggested that the effect persisted when people interacted with others who were close to them, and it was also applicable to people who were highly prosocial by nature. Overall, our findings highlighted the serious interpersonal consequence of time scarcity and highlighted the crucial role of value orientation in understanding this effect.
Developing a model for child participation in child welfare services
Authors: Henze‐Pedersen Sofie , Bengtsson Tea Torbenfeldt 
Published: February 2024

AbstractIn this article, we develop a model for child participation in child welfare services (CPC). Child participation has gained increasing attention in research, policy and practice in the last couple of decades. Two perspectives have concurrently moved this agenda forward—childhood sociology and children's rights—leading to an almost irrefutable understanding of children as social actors with independent rights. We integrate these perspectives in one model in our CPC model. We base the model on the rights‐based Lundy model of child participation and develop it with theoretical insights from childhood sociology and social work as well as empirical insights from the literature on CPC. To capture the specific conditions of child welfare services and the social world of the child, we add contexts as a new overarching element in our CPC model. We also expand the four elements in the original Lundy model to include time and space, voices, direct and indirect audiences and influence and statutory power. The CPC model is designed to conceptualize how child participation unfolds as both a right of the child a social practice within the specific setting of child welfare services.
Peri‐implant epidermoid cyst: A case report and literature analysis
Authors: Wei Shibo , Zhang Xu , Yu Fei , Guo Shuigen , Wei Hongwu 
Published: February 2024

AbstractBackgroundA peri‐implant cystic lesion is a rare finding, and to date most investigators have considered that its pathogenesis is caused by trauma and infection related to dental implantation. However, the pathogenesis of these cysts remains unclear and is recognized to have multifactorial origins.Case presentationIn February 2021, a 75‐year‐old male patient underwent implant restoration due to mobility of the left maxillary central incisor. The implant achieved good osseointegration and was successfully restored. However, in March 2023, the patient sought treatment due to mobility of the dental implant. Clinical examination showed that the implant had loosened in three directions (vertical, mesial‐distal, and labial‐lingual), and the peri‐implant mucosa was slightly red and swollen. Radiographic examination (cone beam computed tomography) showed a large radiolucent area with clear boundaries involving the cervical and middle portions of the dental implant, and white bone lines were observed at the edge of the low‐density shadow. Intraoperatively, we removed the patient's implant, performed a complete debridement, and conducted bone augmentation surgery in the area of bone defect. Postoperatively, the patient recovered well. The final histopathological result confirmed an epidermoid cyst.ConclusionsPeri‐implant epidermoid cyst is a rare complication that affects the long‐term outcome of implant therapy. This case serves as a warning to clinicians to avoid involving epithelial tissue in the implant site during implant surgery, in order to prevent the potential occurrence of a peri‐implant epidermoid cyst, thereby creating better conditions for the patient's recovery and the long‐term efficacy of the implant.