bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimized table describing the relationship between breast volume and breast size used for implant size selecting in surgery
Authors: Chen Xiaona , Lu Yaya , Sun Guangwu , Sun Tiantian 
Published: December 2023

Abstract
The relationship between breast volume/mass and breast size helps surgeons choose implants with proper size. However, current breast volume/mass table is incomplete or inaccurate. This study aims to compare breast volumes obtained by two methods and achieve a complete relationship between breast volume/mass and breast size. Data of breast volume measured by water displacement method, breast mass predicted by breast tissue cut off in breast reduction surgery, and breast density was acquired by literature research. Breast volume was calculated by breast mass multiply breast density. The quantitative relationship between measured breast volume and calculated breast volume was analysed. It was found that exponential relationship exists between the two kinds of breast volumes. Breast volume table was supplemented according to this relationship and accurate breast mass table was calculated. In the future, more breast volume/mass studies with expanded breast size ranges should be explored to enrich the application group.
Response of soil fungal community in winter wheat to warming and fertilization regimes
Authors: Han Ning , Yang Chaoran , Liu Mengting , Pei Xinyu , Mao Ruilin , Chen Changqing 
Published: December 2023

Abstract
Understanding soil fungal diversity under global warming is significant for the assessment of climate change impacts on soil health and soil nutrient transformation. The interaction effect of warmer temperatures and fertilization regimes on fungal communities in the soils of winter wheat fields is unclear. Two-year potting experiments were conducted under nighttime warming and different fertilization regimes. The two-year continuous temperature increase significantly decreased the soil’s pH. Warming and fertilization did not significantly change the dominant fungal phyla in the soil. However, it significantly increased the soil fungal richness and diversity compared with no warming and no fertilization. Warming increased richness and diversity by 4.15% and 4.24%, respectively, and fertilization increased richness and diversity by 14.15% and 4.27%, respectively. Furthermore, warming significantly increased the relative abundance of Fusarium, which is the causal agent of winter wheat weat root rot, from 1.75–3.62%. However, fertilization reduced the relative abundance of Fusarium, especially under the combined application of organic and inorganic fertilizers, suggesting that organic manure addition could impair soil fungal pathogens under future warming. The structural equation model demonstrated that the influence of soil temperature on fungal diversity was direct and mediated through soil carbon nitrogen ratios. Soil temperature and soil organic matter directly affected soil fungal diversity and were the most significant parameters influencing fungal diversity.
Mathematical Modelling using Full Factorial Design in Response Surface Methodology Applied in the Adsorptive Removal of Dye Basic Blue 9 From Synthetic Aqueous Solutions Onto Oryza Sativa Husk-derived Nano-silica Doped Smectic Clay
Authors: Kepdieu Jean Marie , Djangang Chantale Njiomou , Njimou Jacques Romain , Tchanang Gustave , Ekani Cyprien Joel , Maicaneanu Sanda Andrada , Tizaoui Chedly 
Published: December 2023

Abstract
The present work aimed to use Oryza sativa husk (rice husk) in the fabrication of a nanosilica-doped smectic clay for the adsorption of Basic Blue 9 in synthetic aqueous solutions. Response surface methodology was used to evaluate the effects of the considered factors namely, initial dye concentration (10 - 30 mg/L), initial pH (8 - 11), and contact time (0 - 100 min) on the adsorption process. The regression model was found to be able to predict more than 99 % of the targeted response variation in the studied range (R2 = 99.98 %) based on 95% confidence. The analysis of variance proved the significance and the accuracy of the mathematical model. The F-values (1539.08) and p-values (< 0.05) generated by Minitab21 Sofware©, indicating that almost all the independent factors were statistically significant in the studied ranges. Based on the coefficients, initial dye concentration was more influential, followed by pH and contact time. Also, concentration x pH interaction was more effective followed by concentration x contact time. The pH x contact time interaction was very weak and those results were in accordance with factorial, surfaces, and contours plots. The pseudo-second-order kinetic and Langmuir models fitted well to the experimental data with determination coefficients of 0.976 and 0.965 respectively. Under the optimal conditions (30 mg/L, pH 11, t > 50 min; and adsorbent dose of 0.5 g/L, almost 96.33% of the dye was removed. Os-sm is thus an interesting and effective alternative for the removal of BB9 in aqueous solutions.
Method Development and Validation of Simultaneous Estimation of Olmesartan Medoximil and Hydrcohlorthiazide by RP-HPLC in Pharmaceutical Dosage Form
Authors: M.Harika  , Madhuri P.Laxmi , Kamal B. Raj 
Published: December 2023

Abstract
Olmesartan Medoxomil and Hydrochlorothiazide can be estimated simultaneously in commercial formulations using a straightforward, quick, precise, and accurate reverse phase high performance liquid chromatography approach. A Protocol C18 ENDURO Column (250 × 4.6 mm ×5µ), with a mobile phase composed of Acetonitrile and Water 50:50 v/v, was used to estimate the concentration of the medicines in this combination. At 270 nm, the separation was seen while the flow rate was 1 ml/min. OLM and HCTZ had retention times that were, respectively, 1.4 and 1.9 minutes. For OLM and HCTZ, it was discovered that the technique was linear over the range of 10–50 µg/ml. The technique was successfully used to estimate commercial formulations after receiving ICH guideline validation.
Application of alkali-activated cements for immobilization of dry low-level radioactive waste containing copper ferrocyanide
Authors: Guzii Sergii , Zlobenko Borys 
Published: December 2023

Summary: The possibility of using alkali-activated slag-Portland cement for immobilization of dry radioactive waste containing copper ferrocyanide they been confirmed. Because of optimization, the areas of existence of compositions that provide the criterion requirements for strength have been established. Introduction of magnetite additives in the amount of 14...15 wt. % (factor X1), zeolite in the amount of 6.5...7.5 wt. % (factor X2) and dry radioactive waste on the basis of copper ferrocyanide in the amount of 10...12 wt. % (factor X3) provides criterion requirements for compressive strength. The maximum value of strength – 13.2 MPa on the 28th day of hardening is characteristic for the above-mentioned quantities of additives, and it is 1.32 times higher than the standard level of strength. Introduction of zeolite for 6.5...7.5 wt. % allows to reduce the mass and density (1.07 times), radioactivity (1.09 times) of composites. Because of modelling of compound compositions, especially in the expected reactions, the factor X3 shows a weakening factor contributing to the reduction of values of output parameters. Therefore, the introduction of dry radioactive waste into the alkaline slag-Portland cement matrix containing copper ferrocyanide is limited to no more than 12 wt. %. The processes occurring in the volume of the material explain the reduction of mass, density and radioactivity of the compounds. The energy released during radioactive decay of cesium, strontium and other radionuclides is absorbed by magnetite and converted into heat. Heat promotes the removal of physically bound and partially chemically bound water from the structure of tobermorite-like low-basic calcium hydrosilicates, hydrogranates, alkaline-alkaline-earth zeolite-type hydroaluminosilicates, and copper ferrocyanide hydrate shell. However, the passage of radiolysis does not affect the kinetics of strength gain of the compounds, but contributes to the increase of their compressive strength by 1.87 times compared to the strength of the compounds on 7 days of curing
Pneumonia Net: Pneumonia Detection and Categorization in Chest X-ray
Images
Authors: Srivastava Somya , Verma Seema , Das Nripendra Narayan , Sharma Shraddha , Dubey Gaurav 
Published: December 2023

Background:
Pneumonia is one of the leading causes of death and disability due to
respiratory infections. The key to successful treatment of pneumonia is in its early diagnosis
and correct classification. PneumoniaNet is a unique deep-learning model based on CNN for
identifying pneumonia on chest X-rays.

Objective:
A deep learning model that combines convolutional, pooling, and fully connected
layers is presented in this study.

Methods:
In order to learn how to identify cases of pneumonia and healthy controls on chest
X-ray pictures, PneumoniaNet was trained on a large labeled library of such images. A robust
data augmentation technique was adopted to enhance the model generalization and training set
diversity. Standard measures like as accuracy, precision, recall, and F1-score were applied to
PneumoniaNet's performance evaluation.

Results:
The suggested model performed effectively in detecting pneumonia cases with an accuracy of 93.88%.

Conclusion:
The model was evaluated against the current state-of-art methods and showed that
PneumoniaNet outperformed the other models.
Escala de Clima Ético Universitário (ECEU): Propriedades psicométricas
Authors: Frick Loriane Trombini , Matias Zechi Juliana Aparecida , Stelko Pereira Ana Carina , Nozaki Yano Vitor Atsushi , Moreira da Cunha Josafá , Cortez Pedro Afonso 
Published: December 2023

Compreender o Clima Ético Universitário é fundamental para a promoção de políticas e práticas institucionais que visem a formação ética dos atores sociais inseridos neste espaço. Assim, o objetivo deste estudo foi desenvolver um novo instrumento para avaliar o Clima Ético Universitário, para o contexto brasileiro, e analisar as suas evidências de validade baseadas na estrutura interna, consistência interna e validade critério. A amostra foi composta por 3.484 universitários, com idade média de 22,8 anos (DP = 6,92). A escala é um instrumento de autorrelato, com 28 itens. Empregou-se análise fatorial exploratória e confirmatória, resultando em uma escala formada por oito fatores de primeira ordem: segurança, acolhimento institucional à diversidade, engajamento acadêmico institucional, indicadores de vitimização, bem-estar, indicadores de ansiedade e depressão, enfrentamento institucional ao abuso ou assédio, suporte social e institucional percebido, os quais conjuntamente explicam cerca de 71,3% da variância, e um fator de segunda ordem: clima ético universitário. As correlações evidenciaram validade convergente entre os fatores positivos da escala, como segurança, respeito e não discriminação; e validade divergente entre os fatores negativos da escala, como indicadores de vitimização, de ansiedade e depressão, e os fatores de segurança e respeito e não discriminação. Em relação à validade preditiva, verificou-se que seis dos oito fatores foram preditores da ocorrência de respeito e não discriminação. Os resultados apontam a escala como uma alternativa confiável, prática e original para avaliações de Clima Ético Universitário, podendo ser ferramenta de análise que oriente ações institucionais para promoção da convivência ética.
ANTIOXIDANT ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACT FROM SURIAN LEAVES (TOONA SINENSIS)
Authors: LESTARI UCE , MUHAIMIN MUHAIMIN , CHAERUNISAA ANIS YOHANA , SUJARWO WAWAN 
Published: December 2023

Objective: The objective of the present study is to determine antioxidant activities and phytochemical screening of ethanol extract from surian leaves (Toona sinensis).
Methods: This study evaluated the antioxidant activity and conducted phytochemical screening of ethanol extracts obtained from surian leaves. Phytochemical screening was performed using qualitative Thin-Layer Chromatography (TLC), and antioxidant activity was assessed using the DPPH method.
Results: The results revealed the presence of polyphenolic compounds (153.10±0.310 mg/g), tannins, flavonoids (33.19±0.890 mg/g), monoterpenoids, quinones, and saponins with Rf values of 0.607±0.019 (flavonoids) and 0.958±0.019 (terpenoids) 0.513±0.038 (steroids) 0.418±0.019 (phenolics). The antioxidant activity test of the ethanol extract from Surian leaves yielded an IC50 value of 12.351±0.092 ppm, which closely matches the IC50 value of the reference vitamin C (7.805±0.686 ppm).
Conclusion: In conclusion, based on research methods, the ethanol extract of surian leaves contains flavonoid and phenolic compounds which show strong antioxidant activity.
IMMUNOSTIMULANT ACTIVITY OF HANTAP (STERCULIA COCCINEA JACK) LEAVES EXTRACT ON NON-SPECIFIC AND SPESIFIC IMMUNE RESPONSES
Authors: YULIET  , KHAERATI KHILDAH , WIDODO AGUSTINUS , SHARON NELA , TANDI JONI 
Published: December 2023

Objective: This study aims to determine the immunostimulant effect and the effective dose of hantap leaf ethanolic extract against non-specific and specific immune responses.
Methods: The immunostimulant activity of the extract was tested by the carbon clearance method (non-specific response). The effect of the extract on delay-type hypersensitivity/DTH (cellular-specific response) was determined by the paw edema method. The number of leukocyte cells and the percentage of leukocyte cell types were also calculated. The antibody titer (humoral-specific response) test was carried out by the hemagglutination method.
Results: The results of the non-specific immune response demonstrated that three doses of hantap leaf extract, when compared to the negative control, could accelerate the rate of carbon elimination and increase the phagocytosis index. Hantap leaf extract can provide an immunomodulatory effect by increasing the delayed-type hypersensitivity response by showing a greater volume of leg swelling than the negative control received CMC Na 0.5%, which was significantly different (p<0.05), increasing leukocyte count and leukocyte differential and increasing primary and secondary antibody titers. The effective dose of hantap leaves extract was 200 mg/kg body weight.
Conclusion: This study proves that hantap leaf extract has an immunomodulatory effect that increases the immune system (immunostimulant)
POLYHERBAL FORMULATION OPTIMIZATION FROM CLITORIA TERNATEA, ROSMARINUS OFFICINALIS AND AQUILARIA MALACCENSIS USING SIMPLEX LATTICE DESIGN
Authors: AKMAL TUBAGUS , JULIANTI ANDI IKA , SYAMSUDIN SILVIA SYADZA’AH 
Published: December 2023

Objective: This study aimed to optimize the composition of Clitoria ternatea flowers, Rosmarinus officinalis herbs, and Aquilaria malaccensis leaves as a polyherbal formulation.
Methods: The polyherbal formulation (PHF) was systematically optimized using a simplex lattice design generated by Design Expert software. The selected independent variables were the percent of C. ternatea flowers extract (X1), the percent of R. s officinalis herbs extract (X2), and the percent of A. malaccensis leaves extract (X3). The dependent variables were total phenolic contents (Y1) and 2,2-diphenyl-l-picrylhydrazyl (DPPH) radical scavenging activity (Y2).
Results: The results showed that the optimum composition of PHF was C. ternatea flowers extract (10%), R. officinalis herbs extract (80%), and A. malaccensis leaves extract (10%) to obtain 135.794 mg GAE/g dried extract for total phenolic contents and 22.879 µg/ml (IC50) for DPPH radical scavenging activity.
Conclusion: The findings suggest that the polyherbal formulation consisting of C. ternatea flowers (CTF), R. officinalis herbs (ROH), and A. malaccensis leaves (AML), when formulated with the optimal composition has the potential to enhance the total phenolic content and antioxidant activity.
INTERACTION EFFECT OF APIS TRIGONA HONEY, ETHANOLIC EXTRACTS KEMUNING (MURRAYA PANICULATE), YAKON (SMALLANTHUS SONCHIFOLIUS) AND THEIR COMBINATION AGAINST STAPHYLOCOCCUS AUREUS INFECTIONS
Authors: KUSUMA SRI AGUNG FITRI , HERAWATI IRMA ERIKA , RAMDHANI DANNI , RISNAND ALYA 
Published: December 2023

Objective: This study was investigated the antibacterial interaction of Murraya paniculate extract, Smallanthus sonchifolius extract, Apis trigona honey and their combinations for their interaction effect against Staphylococcus aureus ATCC 29213.
Methods: All extracts and honey were evaluated for antibacterial interaction effects both alone and in combination. The disk diffusion method was employed with clindamycin phosphate as the standard antibiotic. The minimum inhibitory concentration (MIC) of the most potent extract was determined using microdilution assays and performed in line with CLSI guidelines.
Results: Among all, S. sonchifolius extract provided the most effective inhibitory activity in higher inhibition than clindamycin phosphate with the range MIC value of 12.5-25% w/v. However, significant different interactions (synergistic, additive and antagonistic) were observed between honey and plant crude extracts. The S. sonchifolius extract displayed additive interaction with M. paniculate extract but antagonistic with A. trigona honey. The antagonistic interaction also produced when M. paniculate extract combined with A. trigona honey. Consequently, their total combination of all tested sample produced an additive interaction.
Conclusion: Thus, we concluded that their combination was ineffective to be used as the antibacterial cocktails against S. aureus infections.
EFFECT OF HYDROXYPROPYL METHYLCELLULOSE (HPMC) AS GELLING AGENT ON PHYSICAL CHARACTERISTICS AND ANTIBACTERIAL POTENTIAL OF TAMOENJU LEAVES EXTRACT GEL (HIBISCUS SURATTENSIS L) AGAINST STAPHYLOCOCCUS AUREUS
Authors: SHARON NELA , YULIET  , PRATIWI RITHA , SULISTIANA SRI 
Published: December 2023

Objective: The target of the study was to know the impact of gelling agent in tamoenju (Hibiscus surattensis L) leaves extract gel and evaluate their physical characteristics and antibacterial potential.
Methods: Three gel formulations were prepared using different concentrations (1, 1.5, and 2%) of gelling agents HPMC and they were evaluated for physical characteristics such as organoleptic, pH, viscosity, spreadability, adhesiveness and antibacterial potential against Staphylococcus aureus.
Results: The consequences of the organoleptic test for three recipes showed a blackish-green color with a thick texture. The addition of tamoenju leaves extract to the gel base affected the base pH from pH around 7 to 4.4-4.5 and increase viscosity of the gel. The spreadability test of F2 and F3 met the standard, namely 5-7 cm. The adhesion test of the three formulas met the standard for more than 4 seconds. The inhibition test against S. aureus for the three formulas had an inhibitory activity ranging from 10-11 mm, categorized as a moderate and strong category.
Conclusion: Antibacterial gel formulations can be made using tamoenju leaf extract. The physical stability parameters of all gel preparations containing tamoenju leaf extract show good results on day 1, but they alter after 36 d of storage. F2 (1.5% of HPMC) outperformed the other formulations in terms of physical stability and has the strongest inhibitory effect against the growth of Staphylococcus aureus.
IN SILICO STUDY OF EUCALYPTOL FROM EUCALYPTUS GLOBULUS LABILL. AGAINST ANGIOTENSIN-CONVERTING ENZYME AS AN ANTIHYPERTENSIVE IN COVID-19 COMORBID
Authors: MUSTARICHIE RESMI , SAPTARINI NYI MEKAR , PRATAMA EDWIN , MEGANTARA SANDRA 
Published: December 2023

Objective: This study aimed to determine the best compound from the 62 compounds of Eucalyptus globulus Labill. as an antihypertensive based on its interaction with angiotensin-converting enzyme (ACE) using the in silico study.
Methods: The study was carried out in silico through molecular docking simulations, analysis of potential compounds using Lipinski’s rule, and ligand-based ADMET prediction on 62 compounds of the E. globulus.
Results: It was found that eucalyptol (1,8-cineole) had the best interaction with the ACE as indicated by a bond energy value (∆G) of-6.40 kcal/mol with an inhibition constant of 20.82 µM, and interacted with key amino acid residues in captopril, namely HIS513, HIS353, TYR523, and ALA354. Eucalyptol also had good physicochemical properties by fulfilling Lipinski’s rule and had the best ADMET profile compared to other compounds.
Conclusion: Eucalyptol was the best antihypertensive against ACE based on amino acid residue interaction, physicochemical properties, and ADMET profile.
Pengenalan Mendeley untuk Pengelolaan Referensi Penulisan Karya Ilmiah bagi Mahasiswa UTD
Authors: Ida Afriliana  , Aries Setyani  
Published: December 2023

Setiap mahasiswa diwajibkan untuk menghasilkan sebuah karya ilmiah, baik itu untuk laporan praktik kerja lapangan atau untuk menuliskan hasil laporan tugas akhir bagi mahasiswa diploma tiga ataupun strata satu. Dalam penulisan karya ilmiah, penulisan sitasi dan pengelolaan referensi jurnal merupakan hal yang penting. Tujuan dilaksanakannya pengabdian masyarakat ini adalah untuk memberikan peningkatan keterampilan kepada mahasiswa Universitas Teknologi Digital (UTD) Kota Tegal dalam hal penulisan sitasi dan pengelolaan artiel jurnal sebagai referensi penulisan karya ilmiah menggunakan Mendeley. Mitra dalam pengabdian masyarakat ini adalah mahasiswa semester 6 dan mahasiswa semester 4, UTD Kota Tegal yang berjumlah 50 mahasiswa. Metode pengabdian masyarakat ini dilakukan dengan ceramah, pelatihan dan pendampingan, mulai dari instalasi mendeley hingga penggunaan mendeley dalam menuliskan sitasi dan penulisan daftar pustaka secara otomatis. Pengambilan data dilakukan dengan cara memberikan kuisioner sebagai instrumen untuk mengetahui sejauh mana pemahaman mahasiswa terhadap materi yang disampaikan hingga impelementasinya pada proses penulisan laporan kerja praktik lapangan (PKL) bagi mahasiswa semester 4 dan penulisan laporan tugas akhir bagi mahasiswa semester 6. Hasil dari pengabdian masyarakat ini adalah semua mahasiswa telah mengimplementasikan mendeley dalan penulisan laporan karya ilmiah dan hanya beberapa mahasiswa yang belum mahir dalam penggunaan sitasi dengan memanfaatan mendeley desktop ini.Dengan adanya pelatihan pengenalan dan implementasi mendeley kepada mahasiswa UTD ini telah memberikan peningkatan kemampuan keterampilan mahasiswa dalam hal penulisan jurnal ilmiah kepada mahasiswa, khususnya untuk melakukan sitasi, pengelolaan artikel jurnal ilmiah sebagai referensi penelitian dan cara menuliskan daftar pustaka secara otomatis.Metode yang digunakan dalam pengabdian masyarakat ini adalah ceramah tentang mendeley dan implementasinya.