bluuebunny/crossref_metadata_2025_split huggingface dataset:
СУЧАСНІ АСПЕКТИ ФОРМУВАННЯ ТА РЕАЛІЗАЦІЇ ПУБЛІЧНОЇ БЕЗПЕКИ: ЄВРОПЕЙСЬКИЙ ДОСВІД
Authors: Мюджахіт Бал , Стельмах Андрій 
Published: December 2023

У статті зазначено, що публічна безпека – це стан і процес, що забезпечує узгодженість цілей національної безпеки поряд із гарантіями виживання, сталого розвитку та добробуту суспільства. Тому вона заснована на загальновизнаних правових нормах та цінностях, що стосуються тривалості та розвитку держави. Саме держава, в ідеальній моделі, є гарантом справедливого перерозподілу громадських товарів та послуг та забезпечує рівні можливості для громадян. У країнах Європейського Союзу дефініція «громадська (публічна) безпека» не має чіткого законодавчого формулювання і, таким чином, її трактування залежить від історичних та інституційних особливостей. Це пов’язано із тим, що у демократичних суспільствах процес забезпечення громадської (публічної) безпеки визначається передусім як реалізація своїх безпосередніх функцій фаховими інститутами (поліцією, національною гвардією, жандармерією тощо), які обирають найоптимальніші механізми та інструменти для забезпечення громадської (публічної) безпеки з метою підтримання громадського порядку у кожному конкретному випадку.
Проведений аналіз європейського досвіду формування та забезпечення публічної безпеки дає підстави зазначити, що державно-правове забезпечення публічної безпеки є основою функціонування її системи. Завдяки йому створюються відповідні умови для діяльності уповноважених суб’єктів у сфері публічної безпеки, контроль за виконанням ними (суб’єктами) обов’язків та повноважень, законодавче гарантування умов для ефективної діяльності.
Публічна безпека за кордоном розглядається як основа забезпечення безпекової життєдіяльності суспільства, тобто як внутрішня безпека держави і є основним компонентом національної безпеки.
Основними державними інституціями в країнах ЄС, які реалізують функції з забезпечення публічної безпеки є поліція та правоохоронні органи, які не лише формують публічну безпеку на певній території, а й забезпечують постійний діалог з громадськістю з метою формування позитивних довірчих відносин між працівниками поліції та мешканцями територій.
Основою якісної та ефективної діяльності поліції за кордоном є професійність, чесність, довіра з боку суспільства.
A TRANSIÇÃO DE PESSOAS TRANSGÊNERO NO SISTEMA DE SAÚDE PÚBLICA BRASILEIRO
Authors: Verbicaro Soares Douglas , Araújo Stephany Lauren Silva , Silva Bruno Gabriel Sousa da 
Published: December 2023

Esse estudo tem por objetivo compreender as realidades vividas por pessoas transgênero no Brasil, em destaque a questão da transição no âmbito da saúde pública. Nesse sentido, busca-se compreender como ocorre essa transição e o acesso a cirurgia de redesignação sexual, com a análise dos obstáculos encontrados pela comunidade trans na concretizaçaõ desse direito garantido desde 2008, por meio da Portaria n° 1.707. Dessa forma, será empregada uma investigação qualitativa e multidisciplinar, baseada no regramento nacional sobre a viabilidade ou não de procedimentos realizados pelo sistema único de saúde brasileiro. Utilizou-se a pesquisa bibliográfica, documental e doutrinaria, com uma abordagem qualitativa-quantitativa dos dados disponibilizados pelo Sistema Público de Saúde (SUS) sobre a quantidade de cirurgias e procedimentos ambulatoriais realizados durante os anos.Assim, a presente pesquisa buscará contestar a eficácia dos processos disponíveis para a transição de pessoas transgêneros, além promover a discussão sobre a inercia estatal de garantir a concretização desse direito à saúde e dignidade humana.
ACCOUNTABILITY JUDICIAL INTERNA
Authors: Barroso Ana Beatriz de Mendonça , Andrade Mariana Dionísio de 
Published: December 2023

A pesquisa tem o intuito de responder ao seguinte problema de pesquisa: a automação proposta pelo Sistema de Estatísticas e Informações do Poder Judiciário no Tribunal de Justiça do Ceará pode ser considerada uma forma de accountability interna? Para isso, é necessário tratar de temas como accountability, a contribuição do CNJ para o Poder Judiciário, e fiscalização no TJCE sobre o trabalho realizado pelas varas de violência doméstica e familiar. A abordagem metodológica é do tipo bibliográfica e documental, qualitativa e quantitativa, com base em dados secundários obtidos no Site do CNJ e informações repassadas pela Coordenadoria de Estatísticas do TJCE. Aplica-se o critério objetivo da amostra intencional na escolha de análise apenas das Unidades Judiciárias de violência Doméstica e Familiar do Estado do Ceará para se obter êxito nas respostas que se concentram no período de 2017 e 2019. Conclui-se que o SEI pode ser considerado como uma forma de accountability interna devido a sua integração com os funcionários que podem acompanhar sua evolução e desempenho, além de ser uma forma de plataforma informacional a ser repassada ao CNJ para realizar sua própria fiscalização, incentivando atualização mais positiva quanto à produtividade e eficácia no SEI
Presentation and Outcome of Children with Kawasaki Disease: Experience in A Tertiary Care Hospital in Bangladesh
Authors: Zabeen Fahmida , Hassan M Quamrul , Nazrin Tahera , Farheen Chowdhury , Mohammad Iqbal Abu Sayeed , Hossain M Istiaque , Sultana Sabina , Farooq Nusrat 
Published: December 2023

Background: Kawasaki disease (KD) is an acute difficult-to-diagnose febrile illness in children caused by self limiting vasculitis in medium and small sized arteries.
Objetive: This study has been conducted to analyze its presenting symptoms, clinical course, laboratory findings, and therapeutic options in a tertiary hospital in Bangladesh to aid early diagnosis and optimum management.
Methods: This is a retrospective study where the medical records of 31 children admitted and diagnosed with Kawasaki Disease (KD) in Evercare Hospital Dhaka between 2009 and 2020, were assessed. Through a structured form, the demographic information, clinical profile, laboratory results, and echocardiographic data were obtained from the hospital records and then entered into a Microsoft Excel sheet. Cleaned and verified data were transferred to SPSS program version 23 and analyzed to obtain descriptive statistics.
Results: Out of total 31 patients with KD enrolled, 64.5% of the patients were between six months to five years of age with a median age of three years; 97% had an age below 6 months. Though 68% of patients met all the required criteria for KD, one-third (32%) were diagnosed as incomplete KD with fewer manifestations. Along with high fever in all cases, the most common clinical features were polymorphous rash (90%) and changes in extremities (90%) followed by changes in the lips and oral cavity (77.4%), cervical lymphadenopathy (68%) and conjunctival injection (61%). Common laboratory abnormalities found were anemia (90%), leukocytosis (65%), thrombocytosis especially in the second week (78%), high ESR (100%), and elevated CRP (84%). About 42% of patients had cardiac abnormalities at the onset. Seven children (63.6%) had coronary artery aneurysms (CAA) whereas 18% had coronary dilatations. In subsequent followups, coronary artery changes remained almost the same up to 6-8 weeks. After 3-6 months, 87.5 % of children recovered from cardiac abnormality.
Conclusion: A high index of suspicion for KD and an active search for compatible findings in children with unexplained fever can help in early diagnosis. Timely initiation of IVIG treatment is needed to reduce the risk of cardiac complications. Young infants under six months of age need further careful early suspicion and evaluation because of their incomplete presentation and more vulnerability to developing cardiac complications.
DS (Child) H J 2022; 38(2): 70-78
Socio-demographic Profile and Complications of Measles in Children: A Hospital Based Study
Authors: Rahat Farhana , Abiduzzaman AFM , Khanam Morsheda , Choudhury Ahmed Murtaza 
Published: December 2023

Background: Measles is a self-limited viral disease. But it can cause serious complications in young children and still remains as an important cause of mortality and morbidity in under five children worldwide.
Objectives: The aim of the study was to determine the complications of measles in hospitalized children and to observe the socio-demographic profile of them.
Methods: A prospective observational study was conducted in Dr M R Khan Shishu Hospital and Institute of Child Health from March to December 2019. Children of 6 months to 10 years who came with signs and symptoms of measles according to the case definition criteria by WHO, like fever with maculopapular rash associated with cough, runny nose and conjunctivitis were included in the study. Their sociodemographic profile was recorded and different complications were noted.
Results: A total of 86 children suffering from measles with different complications were admitted during the study period. They were from 6 months to 10 years. Among them 59% were below 1 year, 80% were below 4 years and 94% were less than 7 years. Thirty eight percent children were from lower and thirty percent from middle socioeconomic background. Pneumonia was the main complication found in 62(72%) cases followed by diarrhea 28(32%), oral ulcer 26(30%), croup 5(6%) and febrile seizure 4(4.6%). Most (79%) of the children, had normal nutritional status. Among 62 children aged 9 months to 10 years, only 16(26%) received 2 doses of measles vaccine, 14(23%) only the first dose and 32(52%) was not vaccinated at all. Vaccination rate was poor (27%) in low socio-economic condition. The mortality rate was 1(1.16%).
Conclusion: About 60% of the children, suffering from measles, were less than one year of age. Fifty nine percent of them were not vaccinated. The children developed complications like pneumonia, diarrhea, oral ulcers etc. Vaccination status was poor in low socio-economic condition. So, awareness should be created about timely vaccination of measles.
DS (Child) H J 2022; 38(2): 84-88
Exchange Transfusion in Neonatal Hyperbilirubinemia: Experience of A Tertiary Care Hospital in Dhaka
Authors: Rahman Shyla , Afroze Sharmin , Parvin Ruma , Iman Kazi , Zinnatunnesa  
Published: December 2023

Background: Hyperbilirubinaemia is a benign condition in newborn babies in some infants may become severe, progressing to kernicterus with substantial risk of neonatal mortality and long-term neurodevelopmental impairments. Among many treatment options exchange transfusion (ET) is the standard method for treatment of severe hyperbilirubinemia.
Objectives: To investigate the frequency of primary risk factors for neonatal hyperbilirubinemia leading to ET, to evaluate the complications and immediate outcome of ET.
Methods: This was an observational cross sectional study conducted in Dr. MR Khan Shishu Hospital and ICH, Dhaka. Frequency of primary risk factors for severe neonatal hyperbilirubinemia leading to ET, characteristics of babies undergoing ET, complications and immediate outcome of ET were analyzed among the neonates admitted between January 2017 to February 2021.
Results: Among 61 neonates 49.18% were male and 50.82% were female, 65.57% of neonates were term and 34.43% pre term. The mean gestational age was 37.00 ± 1.50 weeks and mean birth weight was 2619±50gm. The leading causes of jaundice requiring ET were sepsis 31.17%, ABO incompatibility 24.59%, Rh incompatibility 14.75%, PT LBW with sepsis 14.75%, Infant of diabetic mother (IDM) 6.55%, PT LBW 6.55%, and neonatal sepsis with Down syndrome with congenital hypothyroidism 1.63%. Twenty (32.79%) neonates presented with signs of Kernicterus. Seven neonates (35%) presented with lethargy/poor feeding or hypotonic posture, 4(20%) patients had opisthotonus posture/hypertonia, and 9(45%) had convulsion. Nineteen (31.14%) neonates had complications related to ET. The most frequent complication was bradycardia (16.34%), then Catheter block (9.83%), apnaea (6.55%), cardiac arrest (6.55%), hypothermia (4.92%), NEC after ET (1.64%). Immediate outcome was good in 72.13% patients with smooth recovery, 14.75% had neurological deficit and 1.64% died. Among 20 neonates who presented with signs of Kernicterus 35% patients discharged with good recovery, 45% had neurological deficit.
Conclusion: The common causes of exchange transfusion in neonatal jaundice were sepsis, ABO incompatibility, PT LBW, and infants of diabetic mothers. Overall outcome was good few developed neurological deficit.
DS (Child) H J 2022; 38(2): 89-95
Rare Complication of Chicken Pox in Children - Acute Respiratory Distress Syndrome (ARDS): A Case Report
Authors: Yasmin Farhana , Afroz Shireen , Ferdous Tahmina , Tanjila Umme , Baroi Sukriti 
Published: December 2023

Abstract not available
DS (Child) H J 2022; 38(2): 107-110
Mitigasi Bahaya Penguatan Refraksi Gelombang Tsunami Bagi Komunitas Sekolah
Authors: Johan Septi , Supiyati  , Suwarsono  
Published: December 2023

SDIT Nurul Fikri belum perna mendapat pelatihan atau sosialisai mengenai mitigasi gempa dan tsunami, termasuk informasi mengenai peningkatan bahaya akibat penguatan gelombang tsunami yang disebabkan Teluk Sungai Serut. Padahal sekolah ini berada di ujung Sungai serut. Kegiatan pengabdian ini bertujuan untuk Meningkatkan pengetahuan dan pemahaman tentang bahaya penguatan gelombang tsunami akibat amplifikasi dari refraksi gelombang Tsunami yang memasuki teluk Sungai Serut, Mensosialisaikan akses-akses berupa peta jalur evakuasi yang aman dan realistis serta mudah dijangkau pada warga sekolah SDIT Nurul Fikri. Dalam kegiatan pengabdian ini metode yang digunakan adalah metode ceramah, sosialisasi, identifikasi potensi lokal sekolah, tanya jawab dan curah pendapat (brain storming) serta pembuatan pocket book. Berdasarkan kegiatan yang sudah dilakukan menunjukan bahwa kegiatan pengabdian pada masyarakat di SDIT Nurul Fikri sudah terlaksana dengan baik. Hal ini dapat dilihat dari jumlah kehadiran peserta yang cukup banyak sesuai undangan. Tersusunya pocket book sebagai bahan bacaan khalayak sasaran dalam upaya mitigasi gempa dan tsunami. Hasil evaluasi dari kegiatan menunjukan kegiatan berjalan lancar sesuai dengan yang direncanakan, terlihat antusiasnya khalayak sasaran sebagai stake holders dalam bertanya dan diskusi. Berdasarkan hasil pre-test dan post-test terlihat terjadi peningkatan pemahaman khalayak sasaran 97% terkait pengetahuan mitigasi gempa dan tsunami.
Pengajaran Berbicara Bahasa Inggris Bagi Pemuda di Objek Wisata Marimbunna
Authors: La'biran Roni , Roberto Salu Situru’  , Theresyam Kabanga’  , Resnita Dewi  
Published: December 2023

Keterampilan berkomuniasi dengan wisatawan mancanegara dan wisatawan domestik. Berdasarkan pertimbangan potensi Pemuda Toraja Utara, di Tangrante sebagai daerah kawasan pariwisata, maka program ini didesain berkenaan untuk meningkatkan kompetensi SDM terutama Generasi muda desa Tikala dengan dua fokus yaitu: Kompetensi Bahasa Inggris Praktis. Tujuan Kegiatan Pengabdian kepada Masyarakat ini ini adalah (1) membantu kemampuan berbahasa Inggris praktis, (2) menyiapkan SDM pariwisata yang memiliki kompetensi dan wawasan kepariwisataan yang luas dan kompetensi berbahasa Inggris Praktis. Metode yang digunakan adalah role play atau praktek langsung. Indikatornya dapat dilihat dari sisi peserta, yakni melebihi dari yang direncanakan, yaitu 30 orang, namun yang hadir 49 orang. Materi sajian mencapai 90% dari target ideal yang diharapkan (80%). Daya serap mencapai di atas 60% dari target ideal. Kemampuan berbahasa yang terdiri dari ketrampilan berbicara, membaca, menulis dan menyimak mencapai 50% dari target ideal yang diharapkan.
Evaluasi Kualitas Jalur Pedestrian dengan Menggunakan Walkability Analysis di Jalan Kusuma Bangsa Surabaya
Authors: Saputri Diyah Ayu , Tantyo Muhammad Andi Finaldi Nur 
Published: December 2023

Koridor Jalan Kusuma Bangsa adalah salah satu koridor di Kota Surabaya yang di padati dengan area perdagangan dan jasa yang memiliki intensitas aktivitas yang cukup tinggi. Identitas yang terdapat di koridor ini adalah adanya Hi-Tech Mall dan Taman Remaja Surabaya. Dengan kondisi tersebut, maka perlu adanya penilaian keramahan koridor Jalan Kusuma Bangsa dengan menggunakan walkability analysis. Penelitian ini menggunakan metode deskriptif kualitatif untuk menggali serta menjelaskan fenomena secara mendetail. Hasil dari penelitian ini adalah nilai tingkat walkability Jalan Kusuma Bangsa Kota Surabaya dengan menggunakan 7 kriteria diantaranya Connected, Convivial, Conspicuous, Comfortable, Conveniet, Coexistence dan Commitment. Dapat disimpulkan bahwa tingkat walkability pada Jalan Kusuma Bangsa memiliki nilai yang kurang pada keramahan, kenyamanan, kemudahan dan keikatan. Hal ini ditunjukan dengan tactical paving yang tidak merata, penerangan jalan yang tidak maksimal dimalam hari, banyaknya gangguan fisik pada trotoar dan tindak vandalisme yang memberikan kesan tidak aman pada pengguna.
Investigation of the «Structure – analgesic activity» Relationship Using Molecular Docking for Cyclooxygenases 1 and 2 in the Series 5-<i>N</i>-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thiones
Authors: Buzmakova N. A. , Аndryukov K. V. , Zamaraeva T. M. , Rudakova I. P. , Podchezertseva K. V. , Goman A. S. , Avdeeva E. V. , Slepova N. V. , Dozmorova N. V. 
Published: December 2023

Introduction. Molecular modeling methods are very popular in the scientific community at the present time. The value of the pharmacological action depends on the affinity of the substance to the biological target. Molecular docking makes it possible to assess the degree of affinity of the studied compound with the active center of the molecular target. The enzyme cyclooxygenase (COX) plays a key role in the cascade of synthesis of proinflammatory cytokines and, as a consequence, in pain.Aim. To identify the dependence "structure – analgesic activity" using the method of molecular docking for cyclooxygenase type 1 and type 2 in the series of 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions.Materials and methods. 19 compounds 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions are objects of research The study of the interaction of tetrahydropyridine derivatives with COX 1 and 2 was carried out by the method of molecular docking by the AutoDock 4 program using scoring functions.Results and discussion. Molecular docking of 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions (I–XIX) with COX 1 and 2 is described. Quantitative studies of the "structure – analgesic activity" in the studied series of compounds of the dependence of experimental values of analgesic activity (ААex.) on scoring functions (BeCOX1, KiCOX1, BeCOX2, KiCOX2) and physico-chemical descriptors (log Ppred., рКаpred., рКvpred.) were performed. By checking on an independent sample of 5 compounds, equation No. 3 (ААpred. 3 = 32,6215 – 4,4894 × Becox1 + 0,0066 × Kicox1 + 3,6032 × log Ppred. (R = 0,854, F = 9,01, S = 7,73, Q2LOO = 0,53) was found, with a high value of the correlation coefficient of the predicted values ААex. with experimental values (Rpred. = 0,878) and a minimum forecast error (Spred. = 6,74).Conclusion. The "structure-activity" models for predicting analgesic activity in a series of 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions are obtained. The result of the prediction of biological activity is confirmed by the values of the correlation coefficient (R) obtained when testing models on independent samples.
Assessment of Antihypoxic Activity of S-analoges of Dihydropyrimidin-2-ones and Their Condensed Derivatives
Authors: Buzmakova N. A. , Zamaraeva T. M. , Ivkin D. Yu. , Apushkin D. Yu. , Slepova N. V. , Dozmorova N. V. 
Published: December 2023

Introduction. Antioxydant activity, membrane stabilizing and cytoprotective effect of dihydropyrimidin analoges are widely described in various literary sources. One of the importantant mechanisms of action of antioxidants is their antihypoxic activity. It is the ability to increase tissue resistance to hypoxia. The search for drugs to increase the body's resistance under hypoxic conditions is an actual task in experimental and clinical pharmacology.Aim. Study of the antihypoxic activity of new S-analogs of dihydropyrimidin-2-ones and their condensed derivatives in various models of hypoxia.Materials and methods. 13 compounds S-analogs of dihydropyrimidin-2-ones and their condensed derivatives are objects of research. Their structure has been confirmed by spectroscopy methods. The antihypoxic activity was carried out by recommended methods for preclinical study of new pharmacological substances.Results and discussion. This paper presents the results of testing the obtained compounds of different structures on three models of hypoxia. The activity of a number of condensed tricyclic derivatives of dihydropyrimidine-2-thiones was studied in more detail using a model of acute normobaric hypoxia with hypercapnia.Conclusion. The compounds did not demonstrate high antihypoxic activity; some «structure-property» patterns were revealed.
Antimicrobial Activity of New <i>N</i>-substituted Amides of Aroylpyruvic Acids and Their Silver Salts
Authors: Novikova V. V. , Vasilev V. O. , Gein V. L. , Nazarets O. V. , Romanova A. V. , Bobrovskaya O. V. , Buzmakova N. A. 
Published: December 2023

Introduction. An important direction of modern pharmacy is the production of new domestic substances with anti-infectious activity, within the framework of ensuring the technological sovereignty of the state. Optimization of methods for determining antimicrobial activity is an integral part of these studies. Previously obtained silver salts of pyrazoles and pyrazolecarboxamideshad high antimicrobial activity. This work presents the results of determining the antimicrobial activity of new biologically active compounds synthesized by a salt formation reaction with silver ions at the carboxyl group of aroylpyruvic acid amides containing anthranilic acid in the amide fragment.Aim. Obtaining previously unknown amides of aroylpyruvic acids and their silver salts and studying their antimicrobial activity (AMA).Materials and methods. New N-substituted amides of anthranilic acids and their silver salts were obtained by organic synthesis methods. To study their antimicrobial activity, a micromethod of double serial dilutions was used on screening strains of S. aureus ATCC 6538P, E. coli ATCC 25922, as well as E. faecalis ATCC 29212, S. aureus Wood 46, S. abony No. 103/39 for highly active compounds. Additionally, a method of accounting for the results was carried out using the phenomenon of fluorescence in interaction with rezazurin, indicating the presence of living microbial cells.Results and discussion. The presence of antibacterial activity of silver salts 2a and 2b in relation to the studied strains was established: the minimum suppressive concentration (MPC) of compound 2a is 23.4–31.2 micrograms/ml, 2b is 3.9–5.8 micrograms/ml. When taking into account the results of the study of AMA using the phenomenon of fluorescence, it was found that they either coincide with the values of MPC determined visually, or indicate less antibacterial activity. Comparison of these results and seeding of the contents of the wells on a dense nutrient medium with respect to screening strains indicates that the suppression of fluorescence in experimental wells in the range of 99–82 % compared with the control is accompanied by the absence of bacterial growth (bactericidal effect), with fluorescence inhibition of less than 60 %, a pronounced growth of microorganisms is observed. In the intermediate range, the growth of single colonies is observed (bacteriostatic effect).Conclusion. The results of the study showed that the new silver salts of N-substituted amides of aroylpyruvic acids have high antimicrobial activity. The correspondence of the type of antibacterial activity to the degree of fluorescence inhibition was established.