bluuebunny/crossref_metadata_2025_split huggingface dataset:
МОЖЛИВОСТІ ГОЛОВНОГО ТРЕНЕРА УПРАВЛЯТИ ТАКТИЧНИМИ ДІЯМИ ВОЛЕЙБОЛЬНОЇ КОМАНДИ ПІД ЧАС ЗМАГАНЬ
Authors: МОЗОЛЕВ Олександр , КОВАЛЬЧУК Роман 
Published: October 2023

В статті проаналізовані ігри кращих волейбольних команд Чемпіонату України у сезоні 2022-2023 років. Загальна кількість ігор (n=20). Надана експертна оцінка результатів втручання головного тренера в тактичні дії команди під час тайм-аутів (n=207); ефективності замін гравців (n=438); використання відео повторів (n=171). Мета – проаналізувати можливості головного тренера впливати на тактичні дії волейбольної команди під час змагань. Встановлено, що тренер професійної волейбольної команди корегує тактичні і технічні дії гравців під час змагань в залежності від ігрової ситуації та дій суперника. Він має право проводити заміни гравців, брати тайм аути та вимагати від суддів відео повтори спірних епізодів гри. Своїми діями головний тренер впливає на темп гри, емоційне та психологічне налаштування гравців. Він використовує штучно створені паузи в грі для надання тактичних настанов та порад щодо дій гравців у складних епізодах. Використання тайм-аутів у професійному волейболі є одними з найбільш ефективних засобів оперативного управління командою. Під час тайм аутів головний тренер корегує тактичні моделі дій гравців волейбольної команди. Найчастіше він акцентує увагу на зміні схеми взаємодії гравців, визначенні особливостей розташування волейболістів під час складних подач суперника; доведення до гравців особливостей організації дій у захисті та нападі. Встановлено, що у 63,3 % увага головного тренера волейбольної команди акцентується на організації дій у захисті, у 35,3 % на ефективному завершенні атакуючих дій. Заміни гравців найчастіше проводяться з метою зміни тактичної моделі гри команди і проводиться з метою: урізноманітнення тактичних дій команди; вирішення окремих ігрових епізодів на свою користь; отримання додаткових тактичних пауз у грі. Відео перегляд спірних епізодів гри проводяться з метою зміни рішення суддів. Встановлено, що позитивне рішення мають 29,82 % відео переглядів. Використання системи відео повторів позитивно впливає на об’єктивність прийняття суддівських рішень.
ТЕОРЕТИЧНІ ОСНОВИ ФОРМУВАННЯ ГОТОВНОСТІ ДО ПЕДАГОГІЧНОГО ДИЗАЙНУ У ТРЕНЕРІВ З ФУТБОЛУ
Authors: ТИМЕНКО Володимир 
Published: October 2023

У статті звертається увага на відповідність модернізованих дескрипторів Національної рамки кваліфікацій сучасній екзистенційно зорієнтованій філософії освіти. З’ясовуються і формулюються філософські і психолого-педагогічні засади формування готовності до педагогічного дизайну у тренерів з футболу.
Підкреслюється відповідність різних філософських ідей різним видам освітньої філософії тренерів: традиційний освітній перенніалізм тренера – ідеалістичній філософії; освітній есенціалізм – його реалістичному світогляду; освітній прогресивізм – філософії прагматизму; освітній реконструкціонізм – філософії екзистенціалізму.
Екзистенціалізм розглянуто як сучасну філософську теоретичну засаду формування готовності тренерів-реконструкціоністів до педагогічного дизайну – професійного наміру застосовувати інтерактивний метод у футбольно-ігровому проектуванні матчів, в розвитку футбольної культури та здобутті рівнів спеціалізованої спортивної освіти. Тренер-екзистенціаліст засобами педагогічного дизайну створює умови для вибору власної траєкторії розвитку кожним футболістом команди.
Теорію «множинного інтелекту» Г. Гарднера визначено як психолого-педагогічну теоретичну засаду готовності тренера до педагогічного дизайну. Виокремлено складові «множинного інтелекту» тренера з футболу: практичну, емоційну, вербальну. Вказано на складові «механізму спортивної творчості» В. Клименка: психомоторику, енергопотенціал, критичність і на їх відповідність складовим «множинного інтелекту». Детально описано практичну складову і психомоторику як пріоритетні для творчого «множинного інтелекту» сучасного тренера з футболу.
Pathogenic germline variants in patients with breast cancer: conversations across generations, practices and patients’ attitude
Authors: Abdel-Razeq Hikmat , Mustafa Rawan , Abdel-Razeq Sarah , Abu-Fares Hala , Al Masri Sama , Damsees Rana , El-Atrash Mariam , Elemian Shatha , Alkyam Mais , Ammar Khawlah , Bater Rayan , Kderat Marah , Alhajahjeh Abdulrahman 
Published: October 2023

Background: Breast cancer susceptibility genes such as BRCA1, BRCA2, PALB2, CHEK2 and many others are increasingly recognized among our patient population. In addition to their impact on treatment decisions of tested patients themselves, identifying at-risk family members offer opportunities for cancer preventive measures.Methods: This is an observational cross-sectional study of adult breast cancer patients with positive breast-cancer-susceptibility germline variants who received treatment at our institution. Patients with variants of uncertain significance (VUS), or who refused to give consent, were excluded. The data was collected from an eligible sample of breast cancer patients using a structured questionnaire developed by the study team and tested for validity and reliability, as well as a clinical chart review form. Patients were invited to participate in the study during their scheduled oncology clinics visit.Results: 169 patients were enrolled, including 42 (24.9%) with pathogenic/likely pathogenic (P/LP) BRCA1 variants, 84 (49.7%) with BRCA2 and 43 (25.4%) with non-BRCA variants. All patients were female and the mean age was 45 ± 9.9 years. Among 140 eligible patients, 104 (74.3%) underwent prophylactic mastectomy, while 79 (59.0%) of 134 eligible patients had prophylactic bilateral salpingo-oophorectomy (BSO). Results were communicated with family members by majority (n = 160, 94.7%), including 642 first degree female relatives, and 286 (44.5%) of them have taken no action. Fear of positive test results, cost of testing, unwillingness to undergo preventive measures, and social stigma were cited as barriers to genetic testing in 54%, 50%, 34% and 15%, respectively.Conclusion: Risk-reducing interventions including mastectomy and BSO were carried by majority of patients with P/LP variants. However, though the rate of communication of genetic testing results with family members was high, proper preventive measures were relatively low. Cost and fear of cancer diagnosis, were the leading causes that prevented cascade testing in our cohort.
Sanwei sandalwood decoction improves function of the gut microbiota in heart failure
Authors: Ma Kuiying , Bai Tingting , Hu Pengfei , Zhao Ming , Xiu Zhi , Surilige  , Dalintai  , Zhang Qingshan , Wan Quan 
Published: October 2023

ObjectiveTo investigate the effects of Sanwei sandalwood decoction on improving function of the intestinal flora in doxorubicin-induced heart failure in rats.Materials and methodsThirty Sprague–Dawley rats were screened and randomly assigned into a blank group, a model group, and a Sanwei sandalwood decoction group (treatment group). The rat model of heart failure was prepared and established in the latter two groups. After successful model establishment, the treatment group received Sanwei sandalwood decoction by continuous gavage at 2 g/kg, once daily for 4 weeks. The other groups were given an equivalent volume of saline. After the final dose, fecal samples were collected from each group and analyzed by macrogenomics and nontargeted metabolomics to characterize the intestinal flora and associated metabolites.ResultsThe composition of gut microbiota was significantly different between the three groups. There were 778,808 common genes between the blank and model groups, while 49,315 genes were lost and 521,008 were gained in the model group relative to the blank group. At the phylum level, all groups of rat fecal samples were dominated by Firmicutes, Bacteroidota, Actinobacteria, and Proteobacteria. At the genus level, the microbial community composition in all experimental groups of rat fecal samples was dominated by Lactobacillus, Bifidobacterium, Limosilactobacillus, Allobaculum, Prevotella, and Ligilactobacillus spp. Interestingly, cluster analysis was performed on the top 30 KEGG ontology (KO) terms displaying significant differences in relative abundance in the rat fecal microbiome among experimental groups. The relative frequency of posttranslational modification, coenzyme transport and metabolism, cell wall, membrane, and envelope biogenesis in the eggNOG and CAZy databases. In the nontargeted metabolomics, the group principal component analysis revealed that the groups were well distinguished from one another. The different metabolites were screened with VIP &gt;1, and the KEGG different metabolite classification and enrichment analysis revealed that there includes 15 metabolites pathway, including loxoprofen, conifery-l-acetate, trichilin A, and others. The arachidonic acid pathway also accounted for a significant portion of the KEGG pathway classification analysis.ConclusionSanwei sandalwood decoction positively affects the intestinal microbial environment of rats with heart failure, improving the gut dysbiosis that is caused by the condition. This treatment intervention inhibits the growth of pathogenic bacteria and promotes the growth of beneficial species.
Repression of GhTUBB1 Reduces Plant Height in Gossypium hirsutum
Authors: Zhang Lihua , Ma Caixia , Wang Lihua , Su Xiaofeng , Huang Jinling , Cheng Hongmei , Guo Huiming 
Published: October 2023

The original ‘Green Revolution’ genes are associated with gibberellin deficiency. However, in some species, mutations in these genes cause pleiotropic phenotypes, preventing their application in dwarf breeding. The development of novel genotypes with reduced plant height will resolve this problem. In a previous study, we obtained two dwarf lines, L28 and L30, by introducing the Ammopiptanthus mongolicus (Maxim. ex Kom.) Cheng f. C-repeat-binding factor 1 (AmCBF1) into the upland cotton variety R15. We found that Gossypium hirsutum Tubulin beta-1 (GhTUBB1) was downregulated in L28 and L30, which suggested that this gene may have contributed to the dwarf phenotype of L28 and L30. Here, we tested this hypothesis by silencing GhTUBB1 expression in R15 and found that decreased expression resulted in a dwarf phenotype. Interestingly, we found that repressing AmCBF1 expression in L28 and L30 partly recovered the expression of GhTUBB1. Thus, AmCBF1 expression presented a negative relationship with GhTUBB1 expression in L28 and L30. Moreover, yeast one-hybrid and dual-luciferase assays suggest that AmCBF1 negatively regulates GhTUBB1 expression by directly binding to C-repeat/dehydration-responsive (CRT/DRE) elements in the GhTUBB1 promoter, potentially explaining the dwarf phenotypes of L28 and L30. This study elucidates the regulation of GhTUBB1 expression by AmCBF1 and suggests that GhTUBB1 may be a new target gene for breeding dwarf and compact cultivars.
Kelompok Nelayan dengan Usaha Sampingan Transportasi Perahu di Desa Paputungan Kecamatan Likupang Barat Kabupaten Minahasa Utara
Authors: Longdong Florence V , Tumbol Reiny A 
Published: October 2023

Kegiatan PKM di Desa Paputungan terlaksana dengan tujuan untuk meningkatkan pemahaman dan ketrampilan masyarakat nelayan dalam mengelola usahanya terutama dalam menerapkan manajemen keuangan sederhana sereta memberi penguatan potensi diversifikasi usaha sebagai alternatif ketika tidak melakukan penangkapan ikan. Metode yang diterapkan bersifat klasikal, melalui penyuluhan yang diawali dengan pengamatan langsung melalui pra survei dan wawancara yang dilanjutkan dengan diskusi kelompok. Desa Paputungan merupakan salah satu desa pesisir di Kecamatan Likupang Barat yang sebagian besar masyarakatnya adalah nelayan tradisional. Berprofesi sebagai nelayan dan memiliki usaha sampingan jasa transportasi perahu. Hasil kegiatan pengabdian menyimpulkan: usaha sampingan yang dijalankan nelayan masih dikatagorikan sebagai pekerjaan serabutan yang masih jauh sasarannya terhadap promosi pariwisata di wilayah Likupang yang telah ditetapkan sebagai sebagai Kawasan KEK pariwisata. Tujuannya pekerjaan masih sebatas memenuhi kebutuhan ekonomi rumah tangga sehari-hari. Tindak lanjut yang dapat menjadi saran bagi penentu kebijakan: keterlibatan masyarakat dalam menunjang program pariwisata Nasional ini, perlu menjadi perhatian pemerintah disamping dukungan sarana dan prasarana yang memadai.
Penentuan Prioritas Penanganan Jaringan Jalan Provinsi Metode Analytical Hierarchy Process (Ahp) Berdasarkan Provincial/Kabupaten Roads Management System (Pkrms)
Authors: Halich Ilham , Suraji Akhmad , Hidayat Benny 
Published: October 2023

This PKRMS method combined with the Analytical Hierarrchy Process (AHP) method is expected to get optimal road maintenance results, get the required cost budget and prioritize road handling on strategic roads in West Sumatra province. Road maintenance is carried out to provide road services in accordance with the optimal road service life. West Sumatra Province has 58 provincial roads spread throughout the West Sumatra region, the condition of the road is lightly damaged and heavily damaged. Of the 58 provincial roads, there are 5 strategic sections in the object of research, namely: 2 sections which are transportation access, namely Teluk Bayur Nipah-Purus section (P.098) and Simpang Duku-Ketaping section (P.075) and 3 sections which are agricultural and plantation areas, namely Surantih-Kayo Aro Langgai section (P.086), Panti-Simpang Empat section (P.031) and Abai Sangir-Sungai Dareh section (P.056). The study was conducted by Survey and distributed questionnaires. The survey was conducted by recording inventory data, road condition data, road traffic data which was then processed with PKRMS. The types of handling obtained for the five sections are routine maintenance, periodic maintenance and rehabilitation, the largest budget in the following order: P.056 (Rp. 40,970.5 million), P.086 (Rp. 36,252.5 million), P.031 (Rp. 11,480.5 million), P.075 (Rp. 6,633.8 million), and P.098 (Rp. 5,853.1 million), priority road handling sections are in the following order: P.031, P.056, P.086, P.098, and P.075.
The role of serum ferritin, vitamin B12 and vitamin D levels in childhood primary headaches
Authors: YÜCEL Gül 
Published: October 2023

Aim: In this study, it was aimed to investigate the relationship between headache components and serum ferritin, vitamin B12 and vitamin D levels in pediatric patients with migraine and tension-type headache (TTH).
Methods: The data of patients aged 7-17 years who applied to the outpatient pediatric neurology clinic with a complaint of headache and were diagnosed with migraine and TTH based on the International Classification of Headache Disorder (ICHD)-3 beta criteria were evaluated retrospectively.
Results: The mean age of the patients was 13.80 ± 3.89 years in the migraine group and 14.10± 4.17 years in the TTH group. In the migraine group, the duration of the attack was longer and the pain intensity was higher. Unilateral headache, throbbing character, nausea, vomiting, discomfort from light and sound were statistically significantly higher in the migraine group. In patients with migraine, low vitamin D and low ferritin levels were associated with a prolongation of the disease duration and an increase in the frequency of attacks. A decrease in serum iron level was associated with an increase in pain severity and a decrease in vitamin D levels was associated with an increase in attack duration. It was observed that there was an increase in the frequency of attacks with a decrease in serum ferritin levels in the TTH group. No statistically significant correlation was found between headache characteristics and vitamin B12.
Conclusions: Our study shows the necessity of routine evaluation of vitamin D and ferritin levels in childhood primary headaches.
La planeación financiera como base de permanencia de las Micro, Pequeñas y Medianas Empresas
Authors: Vivanco Florido Jesús Salvador 
Published: October 2023

La presente investigación, tiene como objetivo, establecer la necesidad imperiosa que tienen las Micro, Pequeñas y Medianas Empresas, de realizar la Planeación Financiera como base de sus actividades operativas, con el propósito de que el porcentaje de salida o muerte de las Mipymes, no sea tan elevado en relación al porcentaje de entrada o creación de las Mipymes, ya que en la última década el promedio de mortandad en relación a la creación en los países seleccionados, es del 83.5% (Observatorio Mipymes, 2019). La investigación se realizó mediante el método Cualitativo, descriptivo, consistente en la compilación y análisis de artículos relacionados a la presente investigación en diferentes partes del mundo, como Estados Unidos, Inglaterra, Países Anglo sajones, Turquía y Canadá, que mencionan en sus investigaciones el efecto de la falta de apoyo crediticio para las Mipymes, que ha sido motivado por diferentes factores, entre ellos la falta de credibilidad en la información que poseen, así como la falta de garantías y soporte financiero, provocado según nuestro criterio por la falta de una adecuada Planeación Financiera que les permita establecer objetivos claros y rutas de acción para lograrlos. Con base en los resultados de las investigaciones estudiadas, podemos concluir, que la Planeación Financiera es una herramienta indispensable para el desarrollo y permanencia de las Mipymes que les permita obtener recursos para hacer crecer sus empresas sobre bases realistas y sustentadas.
Probiotic&nbsp;potential&nbsp;of&nbsp;bacterial&nbsp;endophytes&nbsp;isolated&nbsp;from&nbsp;leaves&nbsp;of&nbsp;<em style="mso-bidi-font-style: normal;">Murraya</em><em style="mso-bidi-font-style: normal;">&nbsp;</em><em style="mso-bidi-font-style: normal;">koenigii</em><em style="mso-bidi-font-style: normal;">&nbsp;</em>L.
Authors: Bandara A.C. , Abayasekara C.L. , Karunaratne A.M. , Panagoda G.J. 
Published: October 2023

Probiotics are live microorganisms which confer health benefits to the host when administered in adequate amounts. Endophytes, which live in plant tissues between the plant cells, can act as potential probiotic bacteria. The leaves of Murraya koenigii L. is a common cuisine and herbal ingredient used in indigenous medicine. The main objective of the current study was to assess probiotic characteristics of isolated bacterial endophytes of M. koenigii leaves. Young and mature leaves of M. koenigii were collected from sites in the wet and dry zones of Sri Lanka. The endophytes were isolated using three techniques: placing leaf segments, leaf macerations and preparation of pour plates on three different media viz., nutrient agar, Luria-Bertani (LB), and De Man, Rogosa and Sharpe agar (MRS). They were identified from morphological characteristics and preliminary biochemical tests. Probiotic characterization of the isolates was carried out by using a series of standard tests including resistance to low pH, tolerance of bile salts, antimicrobial activity (Escherichia coli and Pseudomonas aeruginosa), antibiotic resistance (Gentamycine), anti-haemolytic activity, and non-DNase activity. Ten endophytic bacteria (two bacilli, eight cocci including two Gram positive cocci, and eight Gram negative cocci and bacilli) were isolated from the young and mature leaf samples collected. While probiotic characterization tests were positive, four isolates showed antibiotic susceptibility. These results indicate the possibility that M. koenigii leaves possess bacterial endophytes with probiotic potential.
Single and combined effect of fluoride and hardness of drinking water on nephrotoxicity: <em>in-vivo</em> study using Wistar rats as an animal model
Authors: Dilrukshi K.T. , Beneragama D.H. , Suresh T.S. , Wanigasuriya J.K.P. , Manage P.M. 
Published: October 2023

Drinking water in areas with a high prevalence of chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka is known to have high concentrations of fluoride and hardness. The present study evaluated the individual and combined effects of water hardness and fluoride on potential nephrotoxicity, using Wistar rats as an animal model. Thirty-five Wistar rats were randomly assigned into five groups (n=7). Test groups F, H, RL, and RH were given de-ionized water containing 1.5 mg/L fluoride, 200 mg/L hardness, 1.5:200 mg/L fluoride: hardness, and 5:800 mg/L fluoride: hardness respectively, while control group C was given de-ionized water. Body weight and daily water consumption were measured. Serum creatinine, urine creatinine, and urinary biomarker KIM-1 were analyzed. Histopathological changes in the kidneys were observed. There were no significant differences in body weights (p>0.05) while daily water consumption was reduced significantly in the test groups RL and RH (p<0.05). A significant increment in serum creatinine in the RL and RH groups (p<0.05), and a significant reduction in urine creatinine in the F, H, RL and RH groups (p<0.05), were recorded compared to the control. However, the highest magnitude of the effect on serum creatinine and urine creatinine was recorded in the RL group. Significant increment in KIM-1 levels were recorded in the RH group (p<0.05) while the RH group indicated a more rapid increment from the 28th day. When considering histopathology, renal tubular changes were observed in the test groups. The individual and combined effects of water hardness and fluoride may contribute to the aetiology of CKDu in Sri Lanka.
Secure CodeCity: 3-dimensional visualization of software security facets
Authors: Wijesiriwardana C. , Wimalaratne P. , Abeysinghe T. , Shalika S. , Ahmed N. , Mufarrij M. 
Published: October 2023

Over the last few decades, the software industry investigated security best practices to guide software developers in producing less vulnerable software products. As a result, security engineering has emerged as an integral part of the software development lifecycle. With the increase in the number of security vulnerabilities discovered, the software industry encountered challenges finding software security experts. Despite the availability of static code analysis tools to detect security vulnerabilities, they are underused due to several reasons such as inadequate usability and the lack of integration support. For example, such tools are deficient in providing enough information, produce faulty warning messages, and miscommunicate with developers. As a solution, this work presents a conceptual framework and a proof-of-concept visualization tool, Secure CodeCity, as an extension to the CodeCity metaphor, to facilitate security analytics. Secure CodeCity extends the CodeCity metaphor into three different granularity levels in 3-dimensional space, facilitating the vulnerability analysis in different granularities. Thus, software practitioners can use Secure CodeCity to obtain useful security-related information such as "What is the most vulnerable class/method in a particular software project?". A between-subjects design-based user study was conducted with 23 subjects using a set of security-related tasks with two benchmark open-source Apache projects. The evaluation results show that Secure CodeCity surpasses the state-of-the-art security analysis tools in terms of correctness, usability, and time efficiency.