bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inflammation and response to nutrition interventions
Authors: Wunderle Carla , Stumpf Franziska , Schuetz Philipp 
Published: January 2024

AbstractThe complex interplay between nutrition and inflammation has become a major focus of research in recent years across different clinical settings and patient populations. Inflammation has been identified as a key driver for disease‐related malnutrition promoting anorexia, reduced food intake, muscle loss, and on a cellular level, insulin resistance, which together stimulate catabolism. However, these effects may well be bidirectional, and there is strong evidence showing that nutrition influences inflammation. Several single nutrients and dietary patterns with either proinflammatory or anti‐inflammatory properties have been studied, such as the long‐chain ω‐3 fatty acids eicosapentaenoic acid or docosahexaenoic acid. The Mediterranean diet combines several such nutrients and has been shown to improve medical outcomes in the outpatient setting. In addition, there is increasing evidence suggesting that inflammation affects the metabolism and modulates the response to nutrition support interventions. In fact, recent studies from the medical inpatient setting suggest that inflammation, mirrored by high levels of C‐reactive protein, diminishes the positive effects of nutrition support. This may explain the lack of positive effects of some nutrition trials in severely ill patients, whereas similar approaches to nutritional support have shown positive results in less severely ill patients. The use of biomarkers, such as C‐reactive protein, may help to identify patients with a lower response to nutrition, in whom other treatment options need to be used. There is need for additional research to understand how to best address the malnourished patient with inflammation by specifically lowering inflammation through anti‐inflammatory medical treatments and/or nutrition interventions.
Where did the water come from? Wetlands and shallow lakes in semi‐arid dunefields from South America during the Pleistocene–Holocene transition
Authors: Tripaldi Alfonsina , Ozán Ivana L. , Heider Guillermo , Orgeira María J. , Forman Steven L. 
Published: January 2024

ABSTRACTStabilized and active dunes and sand sheet deposits abound in a small lake‐dotted semi‐arid region of the Western Pampean Dunefield, Argentina. Here, a multi‐scale and multi‐proxy study of three sites, across a hydrologic gradient from lakes to a dryland with groundwater levels at more than 25 m depth, analyzes calcareous and ferruginous rhizoliths, calcareous crusts, hypocoatings, pedogenic carbonate and amorphous Mn‐oxide precipitates within blowout dunes. These palustrine‐related features indicate significantly wetter conditions that allowed the development of shallow lakes and expanding wetlands during the Pleistocene–Holocene transition, limited by associated optically stimulated luminescence ages between ca. 14.7 and 11.6 ka. These wetter conditions, also identified in other nearby proxy records, may be associated with a strengthened South American Monsoon System, potentially during the Younger Dryas Chronozone, though other geological, ecological and climatic forcings cannot be ruled out with available data. Such a scenario lacks a modern analogue, since current hydrologic excess, evidenced in the formation of lakes and new rivers, is not observed in the localities which record paleolakes. This study underlines the variable conditions for pronounced hydrologic excess in semi‐arid eolian environments in western Argentina with complex ecological, anthropogenic and climatic linkages.
Distribution, abundance, and density of harbor porpoises in Hood Canal, Washington
Authors: Rone Brenda K. , Zerbini Alexandre N. , Falcone Erin A. , Keene Erin L. , Schorr Gregory S. 
Published: January 2024

AbstractHarbor porpoises (Phocoena phocoena) are the only cetaceans routinely sighted in Hood Canal, a narrow fjord that comprises the western edge of Puget Sound, Washington, USA. Harbor porpoises are sensitive to anthropogenic sounds, including noise from recreational and commercial vessel traffic, and the United States Navy, which conducts military training and testing within Hood Canal that can include underwater sound sources. This study was funded as part of the Navy monitoring program to assess potential impacts of naval activities on cetaceans. We conducted vessel‐based line‐transect surveys for harbor porpoises in Hood Canal in 2022–2023 to derive seasonal estimates of abundance and density. We carried out surveys over 37 days and surveyed the entire canal twice per season totaling 2,176 km of on‐effort track line. We recorded 809 on‐effort harbor porpoise groups and 1,385 individuals. Seasonal abundance estimates were lowest in winter (308 animals, 95% CI = 189–503) and gradually increased through spring and summer to a peak of 1,336 animals (95% CI = 826–2,160) in fall. Overall porpoise density was highest in central Hood Canal, an area that includes a designated United States Navy training range, though porpoise sightings were notably absent in a 21‐km2 area adjacent to the naval submarine base within this otherwise high‐density region. Though we collected only a single year of data, these results suggest that harbor porpoise abundance in Hood Canal increased significantly since it was last estimated (2013–2015). The notable seasonal fluctuation of harbor porpoise abundance suggests Hood Canal may host a larger percentage of the overall Washington Inland Waters stock during the fall season, raising important management considerations.
Improvement of vertigo symptoms and acoustic power absorbance in cases with endolymphatic hydrops
Authors: Kobayashi Masumi , Yoshida Tadao , Fukunaga Yukari , Hara Daisuke , Sugimoto Satofumi , Naganawa Shinji , Sone Michihiko 
Published: January 2024

AbstractObjectiveThe pathophysiology and symptoms underlying Meniere's disease (MD) manifest as endolymphatic hydrops (EH), potentially impacting acoustic power absorbance in vestibular EH. The longitudinal effects of middle ear pressure therapy (MEPT) and conservative therapies for EH by magnetic resonance imaging (MRI) and on acoustic power absorbance on wideband acoustic immittance (WAI) were evaluated, and their changes were compared with clinical symptoms.MethodsEleven patients with definite MD or delayed endolymphatic hydrops (DEH), resistant to conservative therapies and who continued MEPT for 1 year, were included. Vertigo scores, hearing levels, acoustic power absorbance on WAI, and degrees of EH on 3‐T MRI were evaluated and compared before and after the treatments.ResultsOne year after the start of MEPT, all cases showed symptomatic improvement in vertigo score; however, the degrees of EH showed no improvements except in one case. In the affected ears with EH, their absorbances on WAI improved, particularly at 1580–1905 or 2400–2953 Hz (p < .05).ConclusionAlleviation of vestibular symptoms with the therapy of MD was not necessarily associated with improved EH. Vestibular symptoms could be related to the change in the impedance of inner ear pressure, which was proven by the normalization of acoustic power absorbance. Assessments of acoustic power absorbance may provide useful information for physiological conditions and causative factors of vertigo in ears with EH.Level of evidence4
Who will undertake corporate social responsibility in supply chain encroachment? Manufacturer or retailer
Authors: Cheng Yonghong , Pan Jiaxin , Gong Yu 
Published: January 2024

AbstractAs the sustainable economy has become more of a consensus, supply chain members, both manufacturer (e.g., Apple, Huawei, Xiaomi, Nike, and P&G) and retailer (e.g., Uniqlo, Walmart, and Bravo), are concentrated on corporate social responsibility (CSR). The literature in this area has investigated the role of CSR, but the optimal preference for CSR concern of supply chain members is not well understood, especially when manufacturer sells directly by implementing encroachment. This paper studies the optimal preference for CSR concern of supply chain members with considering manufacturer encroachment. We develop the supply chain with a manufacturer (M) and a retailer (R), where the manufacturer sells products via a retail channel which in turn sells them to the final consumers. The manufacturer can also implement encroachment to meet consumers directly. Meanwhile, by considering the manufacturer or retailer may have CSR concern, we explore four scenarios using a game‐theoretic framework. Several interesting findings are as follows. First, for the sake of profits, retailer CSR should be encouraged, which may achieve Pareto improvement under certain conditions. Notably, manufacturer encroachment may narrow the “win–win” situation. While for the sake of environmental protection and consumer well‐being, manufacturer CSR should be encouraged. Second, manufacturer implementing encroachment may not be blind, because it may be worse for itself when retailer has CSR concern. Third, manufacturer CSR may aggravate the cannibalization effect of encroaching, while retailer CSR may relieve it.
Gastro‐Intestinal Digested Bovine Milk Osteopontin Modulates Gut Barrier Biomarkers In Vitro
Authors: Li Lu , Chen Juchun , Zheng Yuxing , Lane Jonathan , Hu Ruibiao , Zhu Jianzhong , Fu Xiong , Huang Qiang , Liu Feitong , Zhang Bin 
Published: January 2024

ScopeOsteopontin (OPN) is a multifunctional protein naturally present in mammals’ milk, associated with immune homeostasis and intestinal maturation. This study aims to investigate the protein digestion pattern and the cellular bioactivity of bovine milk OPN digesta in vitro.Methods and resultsA modified INFOGEST static in vitro infant digestion protocol and a Caco‐2/HT‐29 co‐culture cell model are employed to evaluate the digestion properties and the anti‐inflammatory effects of OPN. OPN is resistant to gastric hydrolysis but degraded into large peptides during intestinal digestion. Its 10 kDa digesta permeate with predicted extensive bioactivities protects the co‐culture cell model from the inflammation‐induced dysfunction by dose‐dependently recovering the expression of occludin, claudin‐3, and ZO‐1. Low dosage of OPN significantly decreases the production of IL‐8 and IL‐6, and downregulates the mRNA and protein expression of MyD88, NF‐κB p65, and IκB‐α, whereas a high dose evokes a mild pro‐inflammatory response. Interestingly, anti‐inflammatory effect of OPN digesta is stronger than lactoferrin and whey protein concentrate counterparts.ConclusionThe findings demonstrate that the bioactive peptides released from in vitro infant gastrointestinal digestion of bovine milk OPN alleviates intestinal epithelial cell inflammation by inhibiting NF‐κB pathway activation and potentiates the barrier function of the intestinal epithelium.
Polymer Versus Polymerization Fouling: Basic Deposition Mechanisms During Emulsion Polymerization by the Example of a Vinyl Acetate and Versa 10 Copolymer
Authors: Klinkert Annika , Friedrich Zoe , Glatt Elisabeth , Augustin Wolfgang , Scholl Stephan 
Published: January 2024

AbstractThe deposition process during emulsion polymerization can be classified as both particulate and reaction fouling, but a deeper understanding of the deposition mechanism, especially in combination with the polymerization process, is lacking. Here, a more in‐depth understanding of the deposition mechanism is sought by investigating the fouling formation of a Vinyl acetate and Versa 10 copolymer on a heated stainless steel surface during emulsion polymerization. Its deposition behavior is also compared with the behavior of an already reacted polymer. All possible influencing factors are investigated separately, and the fouling is quantified by the mass based fouling resistance and the fouling layer composition. The fouling rates of both experimental approaches (ongoing reaction versus already reacted polymer) are used to determine the fraction of reaction fouling along the reaction pathway. The solids content and the driving temperature difference are identified as the main factors influencing fouling formation. The deposited material is composed of latex particles and emulsifier with particle size and number depending on the respective equilibrium composition of the fluid phase. The reaction fouling rate is correlated with the proportion of free initiator radicals and the amount of dissolved monomer in the aqueous phase.
Predicting dynamic, motion‐related changes in B0 field in the brain at a 7T MRI using a subject‐specific fine‐trained U‐net
Authors: Motyka Stanislav , Weiser Paul , Bachrata Beata , Hingerl Lukas , Strasser Bernhard , Hangel Gilbert , Niess Eva , Niess Fabian , Zaitsev Maxim , Robinson Simon Daniel , Langs Georg , Trattnig Siegfried , Bogner Wolfgang 
Published: January 2024

AbstractPurposeSubject movement during the MR examination is inevitable and causes not only image artifacts but also deteriorates the homogeneity of the main magnetic field (B0), which is a prerequisite for high quality data. Thus, characterization of changes to B0, for example induced by patient movement, is important for MR applications that are prone to B0 inhomogeneities.MethodsWe propose a deep learning based method to predict such changes within the brain from the change of the head position to facilitate retrospective or even real‐time correction. A 3D U‐net was trained on in vivo gradient‐echo brain 7T MRI data. The input consisted of B0 maps and anatomical images at an initial position, and anatomical images at a different head position (obtained by applying a rigid‐body transformation on the initial anatomical image). The output consisted of B0 maps at the new head positions. We further fine‐trained the network weights to each subject by measuring a limited number of head positions of the given subject, and trained the U‐net with these data.ResultsOur approach was compared to established dynamic B0 field mapping via interleaved navigators, which suffer from limited spatial resolution and the need for undesirable sequence modifications. Qualitative and quantitative comparison showed similar performance between an interleaved navigator‐equivalent method and proposed method.ConclusionIt is feasible to predict B0 maps from rigid subject movement and, when combined with external tracking hardware, this information could be used to improve the quality of MR acquisitions without the use of navigators.
Quantifying 3D MR fingerprinting (3D‐MRF) reproducibility across subjects, sessions, and scanners automatically using MNI atlases
Authors: Dupuis Andrew , Chen Yong , Hansen Michael , Chow Kelvin , Sun Jessie E. P. , Badve Chaitra , Ma Dan , Griswold Mark A. , Boyacioglu Rasim 
Published: January 2024

AbstractPurposeQuantitative MRI techniques such as MR fingerprinting (MRF) promise more objective and comparable measurements of tissue properties at the point‐of‐care than weighted imaging. However, few direct cross‐modal comparisons of MRF's repeatability and reproducibility versus weighted acquisitions have been performed. This work proposes a novel fully automated pipeline for quantitatively comparing cross‐modal imaging performance in vivo via atlas‐based sampling.MethodsWe acquire whole‐brain 3D‐MRF, turbo spin echo, and MPRAGE sequences three times each on two scanners across 10 subjects, for a total of 60 multimodal datasets. The proposed automated registration and analysis pipeline uses linear and nonlinear registration to align all qualitative and quantitative DICOM stacks to Montreal Neurological Institute (MNI) 152 space, then samples each dataset's native space through transformation inversion to compare performance within atlas regions across subjects, scanners, and repetitions.ResultsVoxel values within MRF‐derived maps were found to be more repeatable (σT1 = 1.90, σT2 = 3.20) across sessions than vendor‐reconstructed MPRAGE (σT1w = 6.04) or turbo spin echo (σT2w = 5.66) images. Additionally, MRF was found to be more reproducible across scanners (σT1 = 2.21, σT2 = 3.89) than either qualitative modality (σT1w = 7.84, σT2w = 7.76). Notably, differences between repeatability and reproducibility of in vivo MRF were insignificant, unlike the weighted images.ConclusionMRF data from many sessions and scanners can potentially be treated as a single dataset for harmonized analysis or longitudinal comparisons without the additional regularization steps needed for qualitative modalities.
NMR and multivariate methods: Identification of chemical markers in extracts of pedra‐ume‐caá and their antiglycation, antioxidant, and enzymatic inhibition activities
Authors: Oliveira Edinilze S. C. , Pontes Flávia L. D. , Acho Leonard D. R. , da Silva Bárbara Janaína P. , do Rosário Alessandro S. , Chaves Francisco Célio M. , Campos Francinete R. , Bezerra Jaqueline de A. , Lima Emerson S. , Machado Marcos B. 
Published: January 2024

AbstractIntroductionIn Brazil, the plant group popularly known as “pedra‐ume‐caá” is used in folk medicine for the treatment of diabetes, and its raw material is commonly sold.ObjectiveThe aim of the study was to apply a method for chemical identification of extracts of dry pedra‐ume‐caá leaves using HPLC–high‐resolution mass spectrometry (HRMS) and NMR and develop a multivariate model with NMR data to authenticate commercial samples. In addition, to evaluate the biological activities of the extracts.Materials and MethodsDry extracts of Myrcia multiflora, Myrcia amazonica, Myrcia guianensis, Myrcia sylvatica, Eugenia punicifolia leaves, and 15 commercial samples (sold in Manaus and Belém, Brazil) were prepared by infusion. All the extracts were analysed using HPLC–high‐resolution mass spectrometry (HRMS), NMR, principal component analysis (PCA), and hierarchical cluster analysis (HCA). The antidiabetic effect of extracts was evaluated according to enzymatic inhibition. Their content of total phenols, cell viability, and antioxidant and antiglycation activities were also determined.ResultsHPLC‐HRMS and NMR analysis of these extracts permitted the identification of 17 compounds. 1H NMR data combined with multivariate analyses allowed us to conclude that catechin, myricitrin, quercitrin, and gallic and quinic acids are the main chemical markers of pedra‐ume‐caá species. These markers were identified in 15 commercial samples of pedra‐ume‐caá. Additionally, only the extracts of M. multiflora and E. punicifolia inhibited α‐glucosidase. All the extracts inhibited the formation of advanced glycation end products (AGEs) and showed free‐radical‐scavenging activity. These extracts did not present cytotoxicity.ConclusionThis study revealed the chemical markers of matrices, and it was possible to differentiate the materials marketed as pedra‐ume‐caá. Moreover, this study corroborates the potential of these species for treating diabetes.
The effect of career‐related parental support on life satisfaction among vocational school students
Authors: Zeng Qing , Wang Jinqing , He Yingshi , Huang Feifei , Luo Huijun , Wu Jingwen , Zhang Minqiang 
Published: January 2024

AbstractThe current study examines hope and career adaptability as two potential mediators, parent–child closeness as a moderator of the relationship between career‐related parental support and life satisfaction. A total of 521 vocational high school students responded to this study. The result revealed that hope and career adaptability independently and serially mediated the relationship between parental career‐related support and life satisfaction. Moreover, the moderating effect of parent–child closeness on career‐related parental support and hope was found. When students' parent–child closeness was high (vs. low), the indirect pathway linking parental career‐related support to hope to career adaptability to life satisfaction was stronger. This study enlightens parents should give career‐related support to their children and establish a close bond with children.
Investigating school counselor–parent relationships, interaction, and involvement
Authors: Brown Timothy , Akkurt Mehmet , Green Dee‐Anna 
Published: January 2024

AbstractInvolvement of parents plays a crucial role in the implementation of a comprehensive school counseling program. For this study, 404 parents participated in a national survey conducted in the United States. The purpose of the study was to investigate parents’ perceptions of their involvement with the school counseling program and their relationship with the school counselor. Results suggested concerns regarding school counselor communication and the involvement of parents in their child's education and planning after high school. Results also indicated participants held a positive perception of school counselors (e.g., hopeful, positive, and accepting), their competency, and they felt comfortable with the school counselor.
Impact of Aeolus horizontal line‐of‐sight wind observations on tropical cyclone forecasting in a global numerical weather prediction system
Authors: Okabe Izumi , Okamoto Kozo 
Published: January 2024

AbstractThe satellite Aeolus, carrying a Doppler Wind Lidar instrument, was launched in August 2018. It is the first mission of the European Space Agency to provide wind profiles globally with high vertical resolutions. The significant positive impact of assimilating the horizontal line‐of‐sight (HLOS) wind data from Aeolus on numerical weather prediction has been reported in many works. In this study, in terms of tropical cyclone (TC) forecasting, the impact of the assimilated data on the Japan Meteorological Agency's global model was investigated in detail. Especially, the direct effect in each analysis resulting from the increment was studied and validated using a reinitialised analysis experiment. The 23 TCs that occurred in the western North Pacific during the summer of 2020 were focused on in the validation period. The largest improvement of track forecasting was found for cases of the NEAR group in which Aeolus passed within 5 degrees of latitude and longitude from a TC centre. The cases of the EAST or WEST groups in which Aeolus passed east or west of the TC centre also indicated some improvements, suggesting that the prediction accuracy of wind upstream of a TC was important for track forecasting. In the NEAR group cases, the increase in positive bias of the TC central pressure was also observed in the cases wherein Aeolus passed inside the maximum wind radius of the TCs. This is explained by the inability to represent the vorticity field in the upper levels in the analyses. One of the possible reasons for this is the insufficient horizontal resolution of observation. We also include some case studies to assess how Aeolus data improved track forecasting and affected intensity forecasting of TCs, specifically.
Fixed‐time synchronization and energy cost estimation of delayed coupled neural networks
Authors: Xu Zhenyu , Zhu Song , Luo Weiwei , Liu Xiaoyang , Wen Shiping 
Published: January 2024

AbstractThis article concentrates on the fixed‐time synchronization (FTS) and energy cost (EC) problems of delayed coupled neural networks (NNs). A switching controller is proposed and some sufficient conditions are advanced to ensure FTS of delayed coupled NNs based on the comparison theorem. Following that, the required EC is estimated during the control process. The main results of FTS and EC for considered NNs are obtained based on the Lyapunov functions in the sense of vector 1‐norm, 2‐norm, and ‐norm, respectively. Under the same controller parameters, this article shows that the minimum estimation of settling time and EC are sometimes not in one norm sense. Finally, numerical examples are given to show the effectiveness of theoretical results.