bluuebunny/crossref_metadata_2025_split huggingface dataset:
X‐Ray Absorption Spectroscopy Study of Cu0.25V2O5 and Zn0.25V2O5 Aerogel‐Like Cathodes for Lithium Batteries.
Authors: Frabetti Elisa , Deluga Gregg A. , Smyrl William H. , Giorgetti Marco , Berrettoni Mario 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Temperature Dependent X‐Ray Diffraction Study on Gd5Sn4 Compound.
Authors: Yang H. F. , Rao G. H. , Liu G. Y. , Ouyang Z. W. , Liu W. F. , Feng X. M. , Chu W. G. , Liang J. K. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
High‐Pressure Synthesis, Crystal Structure, and Properties of the New Orthorhombic Rare‐Earth meta‐Oxoborates Ln(BO2)3 (Ln: Dy—Lu).
Authors: Emme Holger , Nikelski Tanja , Schleid Thomas , Poettgen Rainer , Moeller Manfred Heinrich , Huppertz Hubert 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Crystal Structure, Polymorphism, and Properties of the New Vanadyl Phosphate Na4VO(PO4)2.
Authors: Panin Rodion V. , Shpanchenko Roman V. , Mironov Andrei V. , Velikodny Yuri A. , Antipov Evgeny V. , Hadermann Joke , Tarnopolsky Vasily A. , Yaroslavtsev Andrei B. , Kaul Enrique E. , Geibel Christoph 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Efficient Asymmetric Transfer Hydrogenation of Activated Olefins Catalyzed by Ruthenium Amido Complexes.
Authors: Chen Ying‐Chun , Xue Dong , Deng Jin‐Gen , Cui Xin , Zhu Jin , Jiang Yao‐Zhong 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Application of Phosphinous Amide Ligands in Palladium Complex‐Catalyzed Asymmetric Allylic Alkylation: Influence of Steric Effects on Enantioselectivity.
Authors: Chen Xuanhua , Guo Rongwei , Li Yueming , Chen Gang , Yeung Chi‐Hung , Chan Albert S. C. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Construction of Arene‐Fused‐Piperidine Motifs by Asymmetric Addition of 2‐Trityloxymethylaryllithiums to Nitroalkenes: The Asymmetric Synthesis of a Dopamine D1 Full Agonist, A‐86929.
Authors: Yamashita Mitsuaki , Yamada Ken‐ichi , Tomioka Kiyoshi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Unusual Reversal of Regioselectivity in Antibody‐Mediated Aldol Additions with Unsymmetrical Methyl Ketones.
Authors: Maggiotti V. , Bahmanyar S. , Reiter M. , Resmini M. , Houk K. N. , Gouverneur V. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Preparation Asymmetric Reduction of Ketones in a Biphasic Medium with an (S)‐Alcohol Dehydrogenase under in situ‐Cofactor‐Recycling with a Formate Dehydrogenase.
Authors: Groeger Harald , Hummel Werner , Rollmann Claudia , Chamouleau Francoise , Huesken Hendrik , Werner Helge , Wunderlich Christine , Abokitse Kofi , Drauz Karlheinz , Buchholz Stefan 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Mild, Efficient and Environmentally Friendly Method for the Regio‐ and Chemoselective Synthesis of Enaminones Using Bi(TFA)3 as a Reusable Catalyst in Aqueous Media.
Authors: Khosropour Ahmad R. , Khodaei Mohammad M. , Kookhazadeh Mehdi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Use of Diamines Containing the α‐Phenylethyl Group as Chiral Ligands in the Asymmetric Hydrosilylation of Prochiral Ketones.
Authors: Mastranzo Virginia M. , Quintero Leticia , Anaya de Parrodi Cecilia , Juaristi Eusebio , Walsh Patrick J. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Diastereoselective Electrochemical Carboxylation of Chiral α‐Bromocarboxylic Acid Derivatives: An Easy Access to Unsymmetrical Alkylmalonic Ester Derivatives.
Authors: Feroci Marta , Orsini Monica , Palombi Laura , Sotgiu Giovanni , Colapietro Marcello , Inesi Achille 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Chiral Bis(oxazoline) Rh(I)‐, Ir(I)‐ and Ru(II)‐Complexes for Asymmetric Transfer Hydrogenations of Ketones.
Authors: Debono Nathalie , Besson Michele , Pinel Catherine , Djakovitch Laurent 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Allylation of Aldehydes, Aldimines and Ring Opening of Terminal Aromatic Epoxides by Scandium Triflate Using Polyethylene Glycol (PEG) as an Efficient Recyclable Medium.
Authors: Choudary Boyapati M. , Jyothi Karangula , Madhi Sateesh , Kantam Mannepalli L. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Evaluation of Loxoprofen and Its Alcohol Metabolites for Potency and Selectivity of Inhibition of Cyclooxygenase‐2.
Authors: Riendeau Denis , Salem Myriam , Styhler Angela , Ouellet Marc , Mancini Joseph A. , Li Chun Sing 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Novel Arylsulfonamides Possessing Sub‐Picomolar HIV Protease Activities and Potent anti‐HIV Activity against Wild‐Type and Drug‐Resistant Viral Strains.
Authors: Miller John F. , Furfine Eric S. , Hanlon Mary H. , Hazen Richard J. , Ray John A. , Robinson Laurence , Samano Vicente , Spaltenstein Andrew 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 1‐Indanones by Intramolecular Friedel—Crafts Reaction of 3‐Arylpropionic Acids Catalyzed by Tb(OTf)3.
Authors: Cui Dong‐Mei , Zhang Chen , Kawamura Masato , Shimada Shigeru 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Readily Synthesized and Highly Active Epoxide Carbonylation Catalyst Based on a Chromium Porphyrin Framework: Expanding the Range of Available β‐Lactones.
Authors: Schmidt Joseph A. R. , Mahadevan Viswanath , Getzler Yutan D. Y. L. , Coates Geoffrey W. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Concise Route to 2‐Amino‐2‐aryl‐3H‐benzofurans and Their Use as Precursors to 3‐Aryl‐3H‐benzofuran‐2‐one and 1H‐Benzofuro[2,3‐b]pyridin‐2‐one Derivatives
Authors: Gerster Michele , Wicki Reto 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Cyclopenta[b]indol‐1‐ones and Carbazol‐4‐ones from N‐(2‐Halophenyl)‐Substituted Enaminones by Intramolecular Heck Reaction.
Authors: Soerensen Ulrik S. , Pombo‐Villar Esteban 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
3‐Trifluoromethyl‐4‐nitro‐5‐arylpyrazoles Are Novel KATP Channel Agonists.
Authors: Peat Andrew J. , Townsend Claire , McKay M. Craig , Garrido Dulce , Terry Christopher M. , Wilson Jayme L. R. , Thomson Stephen A. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Facile Synthesis of 3‐Trimethylsilylindazoles by [3 + 2]Cycloaddition Reaction of Lithium Trimethylsilyldiazomethane with Benzynes.
Authors: Shoji Yoshimichi , Hari Yoshiyuki , Aoyama Toyohiko 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
N‐[1‐Aryl‐2‐(1‐imidazolo)ethyl]‐guanidine Derivatives as Potent Inhibitors of the Bovine Mitochondrial F1F0 ATP Hydrolase.
Authors: Atwal Karnail S. , et al. et al. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Optically Active α,β‐Unsaturated Triazolyl Alcohols via Chiral Auxiliary‐Modified NaBH4 Reduction of the Corresponding Ketones.
Authors: Zhou Zhenghong , Tang Yilong , Wang Lixin , Zhao Guofeng , Zhou Qilin , Tang Chuchi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Microwave‐Induced in situ Wittig Reaction of Salicylaldehydes with Ethyl Chloroacetate and Triphenylphosphine in Solventless System.
Authors: Valizadeh H. , Shockravi A. , Heravi M. M. , Ghadim H. Abbasi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Antimicrobial Activity of the Dithiocarbamates of Anabasine, Piperidine and Morpholine.
Authors: Baikenova G. G. , Abdulina G. A. , Gazaliev A. M. , Fazylov S. D. , Kudaibergenova S. Zh. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Subtype Selective NMDA Receptor Antagonists: Evaluation of Some Novel Alkynyl Analogues.
Authors: Kornberg Brian E. , Nikam Sham S. , Wright Jon L. , Kesten Suzanne R. , Meltzer Leonard T. , Coughenour Linda , Barr Bridget , Serpa Kevin A. , McCormick Julie 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel Class of Apical Sodium‐Dependent Bile Acid Transporter Inhibitors: The Amphiphilic 4‐Oxo‐1‐phenyl‐1,4‐dihydroquinoline Derivatives.
Authors: Kurata Hitoshi , Suzuki Sayaka , Ohhata Yasuo , Ikeda Takuya , Hasegawa Toru , Kitayama Ken , Inaba Toshimori , Kono Keita , Kohama Takafumi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Fluorinated Dihydroquinolines as Potent n‐NOS Inhibitors.
Authors: Jaroch Stefan , Rehwinkel Hartmut , Hoelscher Peter , Suelzle Detlev , Burton Gerardine , Hillmann Margit , McDonald Fiona M. , Miklautz Heribert 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
An Efficient One‐Pot Synthesis of Annulated Pyridines Utilizing a Directed ortho‐Metalation/Transmetalation Approach.
Authors: Davies Antony J. , Brands Karel M. J. , Cowden Cameron J. , Dolling Ulf‐H. , Lieberman David R. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel Cu‐Catalyzed Three‐Component One‐Pot Synthesis of Dihydropyrimidin‐2(1H)‐ones Using Microwaves under Solvent‐Free Conditions.
Authors: Gohain Mukut , Prajapati Dipak , Sandhu Jagir S. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Efficient One‐Pot Synthesis of 2‐Oxo‐1,9a‐dihydro‐2H‐pyrido[1,2‐a]pyrimidine Derivatives.
Authors: Adib Mehdi , Yavari Hossine , Mollahosseini Mehdi 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Benzodiazepine‐Based Selective Inhibitors of Mitochondrial F1F0 ATP Hydrolase.
Authors: Hamann Lawrence G. , Ding Charles Z. , Miller Arthur V. , Madsen Cort S. , Wang Paulina , Stein Philip D. , Pudzianowski Andrew T. , Green David W. , Monshizadegan Hossain , Atwal Karnail S. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
1,3‐Dipolar Cycloadditions of Azomethine Ylides to Alkenylboronic Esters. Access to Substituted Boron Analogues of β‐Proline and 3‐Hydroxypyrrolidines.
Authors: Belfaitah Ali , Isly Muriel , Carboni Bertrand 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
(2,7‐Disubstituted‐1,8‐biphenylenedioxy)bis(dimethylaluminum) as Bidentate Organoaluminum Lewis Acids: Elucidation and Synthetic Utility of the Double Electrophilic Activation Phenomenon.
Authors: Ooi Takashi , Takahashi Makoto , Yamada Masao , Tayama Eiji , Omoto Kiyoyuki , Maruoka Keiji 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel Metabolite from the Hybrid Soft Coral Sinularia maxima x Sinularia polydactyla: A Biosynthetically Mixed Skeleton Linking Cembrane and Africanane Terpenoids.
Authors: Kamel Haidy Nasr , Fronczek Frank R. , Fischer Nikolaus H. , Slattery Marc 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Rapid Assembly of Polycyclic Substances by a Multicomponent Cascade [4 + 2]—[2 + 2] Cycloadditions: Total Synthesis of the Proposed Structure of Paesslerin A.
Authors: Inanaga Kazato , Takasu Kiyosei , Ihara Masataka 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Bile Acid Amides Derived from Chiral Amino Alcohols: Novel Antimicrobials and Antifungals.
Authors: Hazra Braja G. , Pore Vandana S. , Dey Sanjeev Kumar , Datta Suchitra , Darokar Mahendra P. , Saikia Dharmendra , Khanuja S. P. S. , Thakur Anup P. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Design of Small Molecule Ketoamide‐Based Inhibitors of Cathepsin K.
Authors: Catalano John G. , Deaton David N. , Long Stacey T. , McFadyen Robert B. , Miller Larry R. , Payne J. Alan , Wells‐Knecht Kevin J. , Wright Lois L. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Lysyl 4‐Aminobenzoic Acid Derivatives as Potent Small Molecule Mimetics of Plasminogen Kringle 5.
Authors: Sheppard George S. , Kawai Megumi , Craig Richard A. , Davidson Donald J. , Majest Sandra M. , Bell Randy L. , Henkin Jack 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Asymmetric Synthesis of N‐Protected Amino Acids by the Addition of Organolithium Carboxyl Synthons to ROPHy/SOPHy‐Derived Aldoximes and Ketoximes.
Authors: Cooper Tracey S. , Laurent Pierre , Moody Christopher J. , Takle Andrew K. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Concise and Stereocontrolled Syntheses of Phosphonate C‐Glycoside Analogues of β‐D‐ManNAc and β‐D‐GlcNAc 1‐O‐Phosphates.
Authors: Wen Xianghui , Hultin Philip G. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Embellished Bicyclo[2.2.2]octenones and a Sigmatropic 1,2‐Acyl Shift in an Excited State: A Novel and Stereoselective Route to (.+‐.)‐Hirsutic Acid C and Complicatic Acid.
Authors: Singh Vishwakarma , Tosh Dilip K. , Mobin Shaikh M. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Furanaphin: A Novel Naphtho[2,3‐c]furan‐4(1H)‐one Derivative from the Aphid Aphis spiraecola Patch.
Authors: Horikawa Mitsuyo , Noguchi Tadashi , Takaoka Shigeru , Kawase Masaki , Sato Masao , Tsunoda Tetsuto 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Hydroamination of Olefin in a Special Conjugated Spiroketal Enol Ether System, Diastereoselective Synthesis of Amino‐Containing Tonghaosu Analogues.
Authors: Yin Biao‐Lin , Hu Tai‐Shan , Wu Yu‐Lin 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
The Design and Synthesis of Sulfonamides as Caspase‐1 Inhibitors.
Authors: Harter William G. , Albrecht Hans , Brady Kenneth , Caprathe Bradley , Dunbar James , Gilmore John , Hays Sheryl , Kostlan Catherine R. , Lunney Beth , Walker Nigel 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of New Thiophene and Benzo[b]thiophene Hydrazide Derivatives as Human NPY Y5 Antagonists.
Authors: Galiano Silvia , Erviti Oihana , Perez Silvia , Moreno Antonio , Juanenea Laura , Aldana Ignacio , Monge Antonio 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Azomethine, Carbonyl and Thiocarbonyl Ylides—Generation and Intermolecular [3 + 2]‐Cycloaddition of Non‐Stabilized Carbonyl Ylides
Authors: Hosomi Akira , Hojo Makoto , Aihara Hidenori 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Azomethine, Carbonyl and Thiocarbonyl Ylides—Generation of Non‐Stabilized Azomethine Ylides by Decarboxylative Condensation of Aldehydes with N‐Substituted α‐Amino Esters
Authors: Nyerges M. , Toke L. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Molecular Engineering of Extended Chiral and Enantiopure Multiporphyrinic Architectures: Towards the Control of Their Physicochemical Properties
Authors: Solladie Nathalie , Aubert Nicolas , Gisselbrecht Jean‐Paul , Gross Maurice , Sooambar Chloe , Troiani Vincent 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Heterogeneous Asymmetric Catalysis: Mechanisms and Applications
Authors: Carneiro Jose Walkimar de M. , de Oliveira Ceciliana da S. B. , Passos Fabio B. , de Souza Paulo Rogerio N. , Aranda Donato A. , Hernandez‐Valdez Ricardo , Gomes Jr. Marlito , Puzer Luciano , Sabino Silvio Jose , Antunes O. A. C. 
Published: May 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Probing the Basicity of Regular and Defect Sites of Alkaline Earth Metal Oxide Surfaces by BF3 Adsorption: A Theoretical Analysis
Authors: Di Valentin Cristiana , Locati Corrado , Pacchioni Gianfranco 
Published: May 2004

AbstractThe basicity of regular and low‐coordinate (LC) sites (steps, edges and corners) at the surface of alkaline earths with NaCl structure (MgO, CaO, SrO, and BaO) has been investigated by using BF3 as a probe molecule. BO and BF distances; OBF bond angles; BF asymmetric stretching frequencies; O, B and F 1s core‐level binding energies; and the interaction energy of adsorbed BF3 were determined by means of DFT calculations on cluster models. These adsorption properties were compared with those of complexes of BF3 with molecules with various basicities (water, ammonia, phosphine, etc.). We show that many properties of adsorbed BF3, and in particular the experimentally accessible shifts in vibrational frequency, in B and F 1s core levels, and in BF3 desorption temperature, exhibit a linear correlation with the surface basicity as measured by the vertical ionization potential of the oxide anions. On the other hand, shifts of the O 1s core level binding energy do not provide a simple way to detect surface basicity. On a given oxide surface, the differeing basicities of various sites result in measurable differences in adsorption properties. This suggests the potential use of BF3 as a probe molecule for titrating LC sites on the surface of ionic oxides.
Novel metalloprotease–disintegrin, meltrin ϵ (ADAM35), expressed in epithelial tissues during chick embryogenesis
Authors: Watabe‐Uchida Mitsuko , Masuda Aki , Shimada Naoko , Endo Masateru , Shimamura Kenji , Yasuda Kunio , Sehara‐Fujisawa Atsuko 
Published: May 2004

AbstractMembers of the ADAM (a
disintegrin and metalloprotease) family are involved in fertilization, morphogenesis, and pathogenesis. Their metalloprotease domains mediate limited proteolysis, including ectodomain shedding of membrane‐anchored growth factors and intercellular‐signaling proteins, and their disintegrin domains play regulatory roles in cell adhesion and migration. In screening for cDNAs encoding chicken ADAM proteins expressed during muscle development, we identified Meltrin ϵ as a novel member of this family. To elucidate its functions, we investigated its expression during development by using antibodies raised against its protease domain. In the somites, Meltrin ϵ protein was specifically expressed in the myotomal cells, which delaminate from the dermomyotome to form epithelial sheets. It was also found in the surface ectoderm, lens placodes, otic vesicles, and the gut epithelia. Basolateral localization of Meltrin ϵ in these epithelial cells suggests its unique roles in the organization of the epithelial tissues and development of the sensory organs and the gut. Developmental Dynamics 230:557–568, 2004. © 2004 Wiley‐Liss, Inc.
Laser capture microdissection (LCM) for analysis of gene expression in specific tissues during embryonic epithelial–mesenchymal transformation
Authors: Nawshad A. , LaGamba D. , Olsen B.R. , Hay E.D. 
Published: May 2004

AbstractThe analysis of gene expression in developing organs is a valuable tool for the assessment of genetic fingerprints during the various stages of tissue differentiation and epithelial–mesenchymal transformation (EMT). However, the variety of differentiating cells and the close association of epithelial and mesenchymal cells makes it difficult to extract protein and mRNA from specific cells and tissue and, thus, to assign expressed genes to specific cell populations. We report here the analysis of LEF1 mRNA in epithelial and mesenchymal cells isolated by LCM from different stages of EMT during development of the mouse palate and describe our techniques in detail. By applying a laser capture microdissection (LCM) technique and real‐time polymerase chain reaction, we were able to determine mRNA levels that accurately reflect changes in gene expression in specific cells. The sensitivity of the technique is remarkable. Indeed, the mRNAs can be detected for many proteins too low in abundance to stain with antibodies. These techniques will enable embryologists to collect homogeneous groups of cells from heterogeneous populations in developing organs, which otherwise would not be available for gene analysis. Developmental Dynamics 230:529–534, 2004. © 2004 Wiley‐Liss, Inc.
Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
Authors: Olson L.E. , Roper R.J. , Baxter L.L. , Carlson E.J. , Epstein C.J. , Reeves R.H. 
Published: May 2004

AbstractTwo mouse models are widely used for Down syndrome (DS) research. The Ts65Dn mouse carries a small chromosome derived primarily from mouse chromosome 16, causing dosage imbalance for approximately half of human chromosome 21 orthologs. These mice have cerebellar pathology with direct parallels to DS. The Ts1Cje mouse, containing a translocated chromosome 16, is at dosage imbalance for 67% of the genes triplicated in Ts65Dn. We quantified cerebellar volume and granule cell and Purkinje cell density in Ts1Cje. Cerebellar volume was significantly affected to the same degree in Ts1Cje and Ts65Dn, despite that Ts1Cje has fewer triplicated genes. However, dosage imbalance in Ts1Cje had little effect on granule cell and Purkinje cell density. Several mice with dosage imbalance for the segment of the Ts65Dn chromosome not triplicated in Ts1Cje had phenotypes that contrasted with those in Ts1Cje. These observations do not readily differentiate between two prevalent hypotheses for gene action in DS. Developmental Dynamics 230:581–589, 2004. © 2004 Wiley‐Liss, Inc.
Stereochemistry of Caracurine V, iso‐Caracurine V, Bisnortoxiferine, and Tetrahydrocaracurine V Ring Systems
Authors: Zlotos Darius P. 
Published: May 2004

AbstractThe 3D structures of the Strychnos toxifera alkaloids caracurine V and toxiferine I, and of the related iso‐caracurine V and tetrahydrocaracurine V ring systems were determined by means of NMR spectroscopy and semiempirical calculations. The relative spatial arrangement of the aromatic indole rings is similar in all three “caracurine” ring systems. Opening of both tetrahydrooxepine rings of caracurine V to give the bisnortoxiferine ring skeleton leads to the conformational change of the central eight‐membered ring from a crown form to a boat form, resulting in a considerably changed geometry of the whole ring skeleton. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)