bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender distribution in publishing in five leading optometry journals
Authors: Cardona Genis , Herrera Aitor 
Published: February 2024

AbstractPurposeTo explore gender distribution in authorship and citation parameters of articles published in five optometry journals included in the Ophthalmology category of Journal Citation Reports.MethodsThe Scopus database was used to retrieve all citable articles published in 2011 and 2021 in Optometry and Vision Science, Ophthalmic and Physiological Optics, Clinical Experimental Optometry, Contact Lens and Anterior Eye, and Eye and Contact Lens. Gender of the first, last and single authors of all articles, and citation parameters of articles published in 2011 up to May 2023 were determined. Gender of the editor‐in‐chief and members of the editorial board of these journals was investigated (May 2023).ResultsOnly one journal had a female editor‐in‐chief and three journals had more males than females in their editorial board. In 2011 and 2021, respectively, 40.1% and 48.0% of articles had female as the first authors ( = 5.77; p = 0.02), and 32.7% and 39.6% had female as the last authors ( = 4.61; p = 0.03). Gender parity was observed in one journal for the first author and none for the last author in 2011, and in three journals for the first author and one for the last author in 2021. Regarding combinations of male (M) and female (F) first and last authorship positions, the authors of articles in 2011 were MM (44.5%), FM (22.8%), FF (17.3%) and MF (15.4%), and MM (34.6%), FM (25.8%), FF (22.1%) and MF (17.5%) in 2021. Differences between 2011 and 2021 were statistically significant ( = 9.80; p = 0.02). The proportion of authorship combinations did not show statistically significant differences among journals in 2011 or in 2021. Neither citation nor self‐citation were influenced by gender.ConclusionsGender disparities persist in optometry journals, with females being under‐represented in senior and leadership positions. Increasing the awareness of gender disparity in authorship is a necessary step towards ensuring fairness in science in general, and optometry in particular.
Changes in branched‐chain amino acids in an infant with maple syrup urine disease during perioperative pediatric liver transplant: A case report
Authors: Saeyup Pipat , Tubjaroen Chomchanat , Kamolvisit Wuttichart , Chongsrisawat Voranush , Thaveepunsan Winnie 
Published: February 2024

AbstractAn 11‐month‐old female infant diagnosed with classic subtype IB maple syrup urine disease underwent living donor liver transplantation. Blood samples for plasma amino acid analysis were collected during the three phases of the operation. Despite the perioperative prophylactic administration of 12.5% hypertonic dextrose solution with insulin and a 20% intralipid emulsion, the blood levels of the branched‐chain amino acids increased dramatically during surgery, consistent with an acute intraoperative metabolic decompensation. However, these blood levels normalized soon after liver transplantation with an excellent outcome. We suggest that the occurrence of an intraoperative metabolic crisis during liver transplantation is not necessarily a sign of graft failure.
Temperature‐smart plants: A new horizon with omics‐driven plant breeding
Authors: Raza Ali , Bashir Shanza , Khare Tushar , Karikari Benjamin , Copeland Rhys G. R. , Jamla Monica , Abbas Saghir , Charagh Sidra , Nayak Spurthi N. , Djalovic Ivica , Rivero Rosa M. , Siddique Kadambot H. M. , Varshney Rajeev K. 
Published: February 2024

AbstractThe adverse effects of mounting environmental challenges, including extreme temperatures, threaten the global food supply due to their impact on plant growth and productivity. Temperature extremes disrupt plant genetics, leading to significant growth issues and eventually damaging phenotypes. Plants have developed complex signaling networks to respond and tolerate temperature stimuli, including genetic, physiological, biochemical, and molecular adaptations. In recent decades, omics tools and other molecular strategies have rapidly advanced, offering crucial insights and a wealth of information about how plants respond and adapt to stress. This review explores the potential of an integrated omics‐driven approach to understanding how plants adapt and tolerate extreme temperatures. By leveraging cutting‐edge omics methods, including genomics, transcriptomics, proteomics, metabolomics, miRNAomics, epigenomics, phenomics, and ionomics, alongside the power of machine learning and speed breeding data, we can revolutionize plant breeding practices. These advanced techniques offer a promising pathway to developing climate‐proof plant varieties that can withstand temperature fluctuations, addressing the increasing global demand for high‐quality food in the face of a changing climate.
Exploring the chain mediating roles of frailty and depressive symptoms in the relationship between pain and cognitive function among nursing home older adults
Authors: Zhao Xia , Si Huaxin 
Published: February 2024

AbstractBackgroundThe prevalence of cognitive decline is high among nursing home older adults. Pain is a vital factor in cognitive function. Furthermore, the current literature lacks the complex association between pain, frailty, depressive symptoms, and cognitive function. The aim of this study was to explore the chain mediating roles of frailty and depressive symptoms in the association between pain and cognitive function among nursing home older adults.MethodsThis is a population‐based cross‐sectional study, conducted in China, of 210 nursing home older adults aged 64–98 years old, who completed the measurements of sociodemographic information, pain, frailty, depressive symptoms, and cognitive function. Mediation analyses tested the indirect effect of frailty and depressive symptoms in the relationship between pain and cognitive function by PROCESS macro.ResultsPain, frailty, as well as depressive symptoms, were negatively related to cognitive function. Frailty mediated the association between pain and cognitive function. Importantly, mediation analyses showed that frailty and depressive symptoms acted as sequential mediators of pain and cognitive function.ConclusionsThese findings have crucial clinical implications, as they suggest targeting physiological and psychological factors in older adults with chronic pain to alleviate cognitive decline.
Asymptotic inference of the ARMA model with time‐functional variance noises
Authors: Cai Bibi , Zhu Enwen , Ling Shiqing 
Published: February 2024

AbstractThis paper studies the autoregressive and moving average (ARMA) model with time‐functional variance (TFV) noises, called the ARMA‐TFV model. We first establish the consistency and asymptotic normality of its least squares estimator (LSE). The Wald tests and portmanteau tests are constructed based on the theory for variable selection and model checking. A simulation study is carried out to assess the performance of our approach in finite samples, and two real examples are given. It should be mentioned that the process generated from the ARMA‐TFV model is not stationary, and the technique in this paper is nonstandard and may provide insights for future research in this area.
Effects of anthropometrics, thrust, and drag on stroke kinematics and 100 m performance of young swimmers using path‐analysis modeling
Authors: Morais Jorge E. , Barbosa Tiago M. , Gomeñuka Natalia A. , Marinho Daniel A. 
Published: February 2024

AbstractThe aim of this study was to understand the interactions between anthropometric, kinetic, and kinematic variables and how they determine the 100 m freestyle performance in young swimmers. Twenty‐five adolescent swimmers (15 male and 10 female, aged 15.75 ± 1.01 years) who regularly participated in regional and national competitions were recruited. The 100 m freestyle performance was chosen as the variable to be predicted. A series of anthropometric (hand surface area–HSA), kinetic (thrust and active drag coefficient (CDA)), and kinematic (stroke length (SL); stroke frequency (SF), and swimming speed) variables were measured. Structural equation modeling (via path analysis) was used to develop and test the model. The initial model predicted performance with 90.1% accuracy. All paths were significant (p < 0.05) except the thrust—SL. After deleting this non‐significant path (thrust—SL) and recalculating, the model goodness‐of‐fit improved and all paths were significant (p < 0.05). The predicted performance was 90.2%. Anthropometrics had significant effects on kinetics, which had significant effects on kinematics, and consequently on the 100 m freestyle performance. The cascade of interactions based on this path‐flow model allowed for a meaningful prediction of the 100 m freestyle performance. Based on these results, coaches and swimmers should be aware that the swimming predictors can first meaningfully interact with each other to ultimately predict the 100 m freestyle performance.
Cytonuclear interplay in auto‐ and allopolyploids: a multifaceted perspective from the Festuca‐Lolium complex
Authors: Shahbazi Mehrdad , Majka Joanna , Kubíková Denisa , Zwierzykowski Zbigniew , Glombik Marek , Wendel Jonathan F. , Sharbrough Joel , Hartmann Stephan , Szecówka Marek , Doležel Jaroslav , Bartoš Jan , Kopecký David , Kneřová Jana 
Published: February 2024

SUMMARYRestoring cytonuclear stoichiometry is necessary after whole‐genome duplication (WGD) and interspecific/intergeneric hybridization in plants. We investigated this phenomenon in auto‐ and allopolyploids of the Festuca‐Lolium complex providing insights into the mechanisms governing cytonuclear interactions in early polyploid and hybrid generations. Our study examined the main processes potentially involved in restoring the cytonuclear balance after WGD comparing diploids and new and well‐established autopolyploids. We uncovered that both the number of chloroplasts and the number of chloroplast genome copies were significantly higher in the newly established autopolyploids and grew further in more established autopolyploids. The increase in the copy number of the chloroplast genome exceeded the rise in the number of chloroplasts and fully compensated for the doubling of the nuclear genome. In addition, changes in nuclear and organelle gene expression were insignificant. Allopolyploid Festuca × Lolium hybrids displayed potential structural conflicts in parental protein variants within the cytonuclear complexes. While biased maternal allele expression has been observed in numerous hybrids, our results suggest that its role in cytonuclear stabilization in the Festuca × Lolium hybrids is limited. This study provides insights into the restoration of the cytonuclear stoichiometry, yet it emphasizes the need for future research to explore post‐transcriptional regulation and its impact on cytonuclear gene expression stoichiometry. Our findings may enhance the understanding of polyploid plant evolution, with broader implications for the study of cytonuclear interactions in diverse biological contexts.
Assembly of CpcL‐phycobilisomes
Authors: Guo Rui , Xu Ya‐Li , Zhu Jun‐Xun , Scheer Hugo , Zhao Kai‐Hong 
Published: February 2024

SUMMARYCpcL‐phycobilisomes (CpcL‐PBSs) are a reduced type of phycobilisome (PBS) found in several cyanobacteria. They lack the traditional PBS terminal energy emitters, but still show the characteristic red‐shifted fluorescence at ~670 nm. We established a method of assembling in vitro a rod‐membrane linker protein, CpcL, with phycocyanin, generating complexes with the red‐shifted spectral features of CpcL‐PBSs. The red‐shift arises from the interaction of a conserved key glutamine, Q57 of CpcL in Synechocystis sp. PCC 6803, with a single phycocyanobilin chromophore of trimeric phycocyanin at one of the three β82‐sites. This chromophore is the terminal energy acceptor of CpcL‐PBSs and donor to the photosystem(s). This mechanism also operates in PBSs from Acaryochloris marina MBIC11017. We then generated multichromic complexes harvesting light over nearly the complete visible range via the replacement of phycocyanobilin chromophores at sites α84 and β153 of phycocyanins by phycoerythrobilin and/or phycourobilin. The results demonstrate the rational design of biliprotein‐based light‐harvesting elements by engineering CpcL and phycocyanins, which broadens the light‐harvesting range and accordingly improves the light‐harvesting capacity and may be potentially applied in solar energy harvesting.
Results of clinical effectiveness of conventional versus Mirasol‐treated Apheresis Platelets in Patients with Hypoproliferative Thrombocytopenia (MiPLATE) trial
Authors: Koepsell Scott A. , Stolla Moritz , Sedjo Rebecca L. , Carson Jeffrey , Knudson Michael , Cook Richard , Fasano Ross , Ngamsuntikul Samantha G. , Cohn Claudia , Gorlin Jed , Delaney Meghan , Slichter Sherrill , Ness Paul , McCullough Jeffrey 
Published: February 2024

AbstractBackgroundThe Mirasol® Pathogen Reduction Technology System was developed to reduce transfusion‐transmitted diseases in platelet (PLT) products.Study Design and MethodsMiPLATE trial was a prospective, multicenter, controlled, randomized, non‐inferiority (NI) study of the clinical effectiveness of conventional versus Mirasol‐treated Apheresis PLTs in participants with hypoproliferative thrombocytopenia. The novel primary endpoint was days of ≥Grade 2 bleeding with an NI margin of 1.6.ResultsAfter 330 participants were randomized, a planned interim analysis of 297 participants (145 MIRASOL, 152 CONTROL) receiving ≥1 study transfusion found a 2.79‐relative rate (RR) in the MIRASOL compared to the CONTROL in number of days with ≥Grade 2 bleeding (95% confidence interval [CI] 1.67–4.67). The proportion of subjects with ≥Grade 2 bleeding was 40.0% (n = 58) in MIRASOL and 30.3% (n = 46) in CONTROL (RR = 1.32, 95% CI 0.97–1.81, p = .08). Corrected count increments were lower (p < .01) and the number of PLT transfusion episodes per participant was higher (RR = 1.22, 95% CI 1.05–1.41) in MIRASOL. There was no difference in the days of PLT support (hazard ratio = 0.86, 95% CI 0.68–1.08) or total number of red blood cell transfusions (RR = 1.12, 95% CI 0.91–1.37) between MIRASOL versus CONTROL. Transfusion emergent adverse events were reported in 119 MIRASOL participants (84.4%) compared to 133 (82.6%) participants in CONTROL (p = NS).DiscussionThis study did not support that MIRASOL was non‐inferior compared to conventional platelets using the novel endpoint number of days with ≥Grade 2 bleeding in MIRASOL when compared to CONTROL.
Effects of intranasal and intramuscular administration of butorphanol and zolazepam‐tiletamine combination on intraocular pressure and tear secretion in New Zealand White rabbits
Authors: Cinar Harun , Yanmaz Latif Emrah , Sirin Muhammed Yusuf 
Published: February 2024

AbstractThis study aimed to compare the effect of intranasal (IN) and intramuscular (IM) administration of butorphanol and zolazepam‐tiletamine (ZT) combination on intraocular pressure (IOP) and tear secretion (TS) in rabbits. Fourteen healthy male New Zealand White rabbits weighing 3.05 ± 0.72 kg, aged between 1 and 2 years old, were included in the study. Animals randomly received 0.5 mg/kg butorphanol and 15 mg/kg ZT combination either with IN or IM administration. IOP and TS were measured at baseline (T0), and followed by 5, 15, 30, 45, and 60 min after drug administration. The sedation variables, the time to onset of sedation, duration of sedation, and sedation scores were also recorded. The route of administration for the butorphanol and ZT combination had no significant effect on the mean IOP (p = .301) and TS (p = .445). Furthermore, there were no significant changes observed in the IOP (p = .472) and TS (p = .348) over time. The time to onset of sedation was earlier in the IN group (4.57 ± 0.79 min) than in the IM group (5.86 ± 0.9 min; p = .0004). The duration of sedation was significantly longer for IM (57.43 ± 3.41 min) compared with IN (45.0 ± 1.91 min; p < .0001). No significant difference in the sedation score was observed between groups at all time points. In conclusion, both IN and IM administration of the butorphanol and ZT combination in rabbits had similar effects on IOP and TS.
Dimensional and spatial computed tomographic abnormalities of the rectum and prostate are only partly reversible after surgical repair of perineal hernia in dogs
Authors: Salonen Hanna M. , Åhlberg Tuuli M. , Laitinen‐Vapaavuori Outi M. , Mölsä Sari H. 
Published: February 2024

AbstractCaudal protrusion of pelvic organs and dilatation and deviation of the rectum with perineal hernia (PH) have not previously been studied using CT, and it is not known how completely the changes normalize after PH repair. Objectives of this prospective experimental case series were to evaluate the dimensions and shape of the rectum and the volume, location, and other features (enhancement pattern, presence of cysts, and mineralizations) of the prostate of 66 dogs on CT before and 3 months after PH repair. The rectal cross‐sectional areas were measured at intrapelvic and caudal locations, and the shape was categorized as straight, deviated, flexure, or caudal fold on dorsal images. According to paired samples t‐tests, the caudal rectal dimensions were significantly larger (P < .001) than the intrapelvic dimensions both before and 3 months after PH repair, and according to linear mixed models, the intrapelvic dimensions increased significantly (P < .001) after repair. Before PH repair, the most common rectal shape was flexure (69.2%); after repair, the number of dogs having a straight rectum increased significantly (P < .001) according to the McNemar paired‐samples proportion test. We were also able to show that rectal dimensions increased after PH repair despite straightening in most dogs. According to the linear mixed model, prostate ratio volume, and according to Wilcoxon signed ranks test, the number of prostates with intraprostatic cysts decreased significantly (both P < .001) after PH repair, but the proportion of prostates located in the caudal or perineal area did not. Small mineralizations remained in some dogs.
On the Lindelöf hypothesis for general sequences
Authors: Broucke Frederik , Weishäupl Sebastian 
Published: February 2024

AbstractIn a recent paper, Gonek, Graham, and Lee introduced a notion of the Lindelöf hypothesis (LH) for general sequences that coincides with the usual LH for the Riemann zeta function in the case of the sequence of positive integers. They made two conjectures: that LH should hold for every admissible sequence of positive integers, and that LH should hold for the “generic” admissible sequence of positive real numbers. In this paper, we give counterexamples to the first conjecture, and show that the second conjecture can be either true or false, depending on the meaning of “generic”: we construct probabilistic processes producing sequences satisfying LH with probability 1, and we construct Baire topological spaces of sequences for which the subspace of sequences satisfying LH is meagre. We also extend the main result of Gonek, Graham, and Lee, stating that the Riemann hypothesis is equivalent to LH for the sequence of prime numbers, to the context of Beurling generalized number systems.
A radiomics model based on transrectal ultrasound for predicting prostate cancer
Authors: Huang Yanhua , Qian Hongwei , Zheng Yuanyuan , Song Huiming , Liu Xiatian 
Published: February 2024

Aim: Prostate cancer (PCa) is one of the most common neoplasms in men. However, the value of ultrasound-based radiomics for diagnosing PCa remains uncertain.Material and methods: We retrospectively analyzed ultrasonic and clinical data from 373 patients. Patients were divided into two groups according to the pathological results. Radiomics features wereextracted from TRUS, and we screened the optimal features to construct radiomics models. Relationships between clinical characteristics and prostate lesions were identified by univariate and multivariate logistic regression analysis. Finally, a clinical-radiomics model was developed, and then visualized in the form of a nomogram.Results: Of the 373 patients, 178 had benign disease and 195 had malignant disease. The support vector machine (SVM) classification model showed the best performance, while the diagnostic performance of the clinical model was poorer than that of the radiomics model (p<0.05) or the combined (clinical-radiomics) model (p<0.05). In general, the combined model demonstrated the highest AUC and proved to be more advantageous.Conclusion: The prediction model we constructed based on TRUS predicted PCa preoperatively with high efficiency. In addition, combining radiomics with clinical factors improved diagnostic accuracy.
Outbreak of Oropouche virus in frontier regions in western Amazon
Authors: Moreira Hillquias Monteiro , Sgorlon Gabriella , Queiroz Jackson A. S. , Roca Tarcio P. , Ribeiro Jessiane , Teixeira Karolaine S. , Passos-Silva Ana Maísa , Araújo Adrhyan , Gasparelo Nadson Willian Felipe , Dos Santos Alcione de Oliveira , Lugtenburg Celina Aparecida Bertoni , Roque Rosemary Aparecida , Villalobos Salcedo Juan Miguel , Pereira Dhelio B. , Vieira Deusilene 
Published: February 2024

ABSTRACT

Oropouche virus (OROV) is characterized as a re-emerging arbovirus of great concern for public health, being responsible for several outbreaks of acute fever identified in Latin American countries, registering more than half a million reported cases. The incidence of reports of this virus is intrinsically favored by environmental conditions, in which such characteristics are related to the increase and distribution of the vector population to areas of human traffic. Moreover, there is a problem regarding the lack of diagnosis in Brazil that aggregates the success of the etiologic agent. Thus, by means of molecular techniques, we identified 27 positive cases of the OROV circulating in border locations in western Amazon, with 44.44% (12/27) of the cohort characterized as infected individuals with reported symptoms, mainly ranging from fever, myalgia, and back pain. Among the positive samples, it was possible to obtain a total of 48.14% (13/27) samples to analyze the S and M segments of Oropouche, which showed similarities among the Brazilian sequences. Thus, it was possible to verify the circulation of the OROV in Rondonia and border areas, in which the tracking of neglected arboviruses is necessary for the genomic surveillance of emerging and re-emerging viruses.

IMPORTANCE
The western Amazon region is known for outbreaks of acute febrile illnesses, to which the lack of specific diagnostics for different pathogens hinders the management of patients in healthcare units. The Oropouche virus has already been recorded in the region in the 1990s. However, this is the first study, after this record, to perform the detection of individuals with acute febrile illness using a screening test to exclude Zika, dengue, and chikungunya, confirmed by sequencing the circulation of the virus in the state of Rondonia and border areas. We emphasize the importance of including diagnostics for viruses such as Oropouche, which suffers underreporting for years and is related to seasonal periods in Western Amazon locations, a factor that has a direct influence on public health in the region. In addition, we emphasize the importance of genomic surveillance in the elucidation of outbreaks that affect the resident population of these locations.
Hilbert–Pólya Operators in Krein Spaces
Authors: Kapustin V. V. 
Published: February 2024

AbstractWe construct some class of selfadjoint operators in the Krein spaces consisting of functions on
the straight line $ \{\operatorname{Re}s=\frac{1}{2}\} $.
Each of these operators is a rank-one perturbation of a selfadjoint operator
in the corresponding Hilbert space
and has eigenvalues complex numbers of the form $ \frac{1}{s(1-s)} $,
where $ s $ ranges over the set of nontrivial zeros of the Riemann zeta-function.