bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functionalization of Biomass-derived Activated Carbon and Electrochemical Reduction for the Recovery of Gold from Mobile Phone Leachate
Authors: Firmansyah Mochamad Lutfi , Amalina Ilma , Rizki Intan Nurul , Alfaza Asmaul Mashad , Jiwanti Prastika Krisma , Jalil Aishah Abdul , Goto Masahiro 
Published: October 2023

AbstractIn this age of cutting-edge technology, electronic equipment consumption, such as mobile phones, has increased tremendously. This was followed by a staggering increase in electronic waste (e-waste). However, it has been known that e-wastes contain higher amounts of precious metals than pristine sources, such as Au, which is valuable as an alternative precious metal source. Due to its various advantages, adsorption has emerged as one of the most common metal removal or recovery methods. A crucial aspect of adsorption is developing a cost-effective adsorbent for selective recovery of Au from the e-wastes. Thus, functionalized biomass-based adsorbent was developed to recover precious metals from e-waste. Functionalized activated carbon (ACIL900) has an appealing high adsorption capacity (116.2 mg g−1) performance and follows the chemisorption route, which fits with the monolayer model. The presence of IL boosts the adsorption efficiency due to its compatible interaction with the metal complexes. Remarkably, ACIL900 could quantitatively adsorb precious metals and several base metals from mobile phone leachate. The selective recovery of Au from the adsorbent was performed by sequential desorption using various solutions. Finally, Au was successfully recovered from the desorption solution using an electrochemical reduction process. ACIL900 was also found to maintain its performance for three adsorption–desorption cycles. This work reported the full recovery of Au from e-waste to its final pure product through the combination of adsorption, sequential desorption, and electrochemical reduction.
How Food Choices Impact on Male Fertility
Authors: Pecora Giulia , Sciarra Francesca , Gangitano Elena , Venneri Mary Anna 
Published: October 2023

Abstract
Purpose of Review
Increasing evidence on the significance of nutrition in reproduction is emerging from both animal and human studies, suggesting an association between nutrition and male fertility. Here, we have highlighted the impact of the various food groups on reproductive hormones and on spermatogenesis, and the effects of classical and latest dietary patterns such as Mediterranean diet, Western diet, intermittent fasting, ketogenic diet, and vegan/vegetarian diet on male fertility.

Recent Findings
Nutrients are the precursors of molecules involved in various body’s reactions; therefore, their balance is essential to ensure the correct regulation of different systems including the endocrine system. Hormones are strongly influenced by the nutritional status of the individual, and their alteration can lead to dysfunctions or diseases like infertility. In addition, nutrients affect sperm production and spermatogenesis, controlling sexual development, and maintaining secondary sexual characteristics and behaviors.

Summary
The consumption of fruit, vegetables, fish, processed meats, dairy products, sugars, alcohol, and caffeine importantly impact on male fertility. Among dietary patterns, the Mediterranean diet and the Western diet are most strongly associated with the quality of semen. Nutrients, dietary patterns, and hormonal levels have an impact on male infertility. Therefore, understanding how these factors interact with each other is important for strategies to improve male fertility.
A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
Authors: Reina-Mahecha Alejandro , Beers Martine J. , van der Veen Hugo C. , Zuhorn Inge S. , van Kooten Theo G. , Sharma Prashant K. 
Published: October 2023

Abstract
Background:
Osteoarthritis (OA) is the most common degenerative joint disease without an ultimate treatment. In a search for novel approaches, tissue engineering (TE) has shown great potential to be an effective way for hyaline cartilage regeneration and repair in advanced stages of OA. Recently, induced pluripotent stem cells (iPSCs) have been appointed to be essential stem cells for degenerative disease treatment because they allow a personalized medicine approach. For clinical translation, bioreactors in combination with iPSCs-engineerd cartilage could match patients needs, serve as platform for large-scale patient specific cartilage production, and be a tool for patient OA modelling and drug screening. Furthermore, to minimize in vivo experiments and improve cell differentiation and cartilage extracellular matrix (ECM) deposition, TE combines existing approaches with bioreactors.

Methods:
This review summarizes the current understanding of bioreactors and the necessary parameters when they are intended for cartilage TE, focusing on the potential use of iPSCs.

Results:
Bioreactors intended for cartilage TE must resemble the joint cavity niche. However, recreating human synovial joints is not trivial because the interactions between various stimuli are not entirely understood.

Conclusion:
The use of mechanical and electrical stimulation to differentiate iPSCs, and maintain and test chondrocytes are key stimuli influencing hyaline cartilage homeostasis. Incorporating these stimuli to bioreactors can positively impact cartilage TE approaches and their possibility for posterior translation into the clinics.
Orientation Mixing in Active Suspensions
Authors: Coti Zelati Michele , Dietert Helge , Gérard-Varet David 
Published: October 2023

AbstractWe study a popular kinetic model introduced by Saintillan and Shelley for the dynamics of suspensions of active elongated particles where the particles are described by a distribution in space and orientation. The uniform distribution of particles is the stationary state of incoherence which is known to exhibit a phase transition. We perform an extensive study of the linearised evolution around the incoherent state. We show (i) in the non-diffusive regime corresponding to spectral (neutral) stability that the suspensions experience a mixing phenomenon similar to Landau damping and we provide optimal pointwise in time decay rates in weak topology. Further, we show (ii) in the case of small rotational diffusion $$\nu $$
ν
that the mixing estimates persist up to time scale $$\nu ^{-1/2}$$

ν

-
1
/
2

until the exponential decay at enhanced dissipation rate $$\nu ^{1/2}$$

ν

1
/
2

takes over. The interesting feature is that the usual velocity variable of kinetic models is replaced by an orientation variable on the sphere. The associated orientation mixing leads to limited algebraic decay for macroscopic quantities. For the proof, we start with a general pointwise decay result for Volterra equations that may be of independent interest. While, in the non-diffusive case, explicit formulas on the sphere allow to conclude the desired decay, much more work is required in the diffusive case: here we prove mixing estimates for the advection-diffusion equation on the sphere by combining an optimized hypocoercive approach with the vector field method. One main point in this context is to identify good commuting vector fields for the advection-diffusion operator on the sphere. Our results in this direction may be useful to other models in collective dynamics, where an orientation variable is involved.
Chitosan decorated cobalt zinc ferrite nanoferrofluid composites for potential cancer hyperthermia therapy: anti-cancer activity, genotoxicity, and immunotoxicity evaluation
Authors: Sharifi Esmaeel , Reisi Fatemeh , Yousefiasl Satar , Elahian Fatemeh , Barjui Shahrbanou Parchami , Sartorius Rossella , Fattahi Najmeh , Zare Ehsan Nazarzadeh , Rabiee Navid , Gazi Elham Pahlevani , Paiva-Santos Ana Cláudia , Parlanti Paola , Gemmi Mauro , Mobini Gholam-Reza , Hashemzadeh-Chaleshtori Morteza , De Berardinis Piergiuseppe , Sharifi Ibrahim , Mattoli Virgilio , Makvandi Pooyan 
Published: October 2023

AbstractCancer, as the leading cause of death worldwide, has been constantly increasing in mortality every year. Among several therapeutics, nanoscale compounds showed promising results in overcoming cancer diseases. There are numerous types of research on the paramagnetic nanoparticles of iron oxide, which cause apoptosis and cancer cell death. In this study, cobalt/zinc/ferrite nanoferrofluid composites (~ 39 nm) were synthesized and decorated with chitosan to enhance the cell entry for potential applications in cancer therapy. The neat and chitosan-adorned cobalt zinc ferrite nanoferrofluid composites (~ 94 nm) displayed superparamagnetic properties. The nanocomposite exhibited anti-cancer activity against WEHI164 cancer cells in a dose- and time-dependent manner. The chitosan-coated nanocomposite was found to induce oxidative stress in WEHI164 cancer cells, as indicated by reactive oxygen species (ROS) production. Furthermore, DNA damage was indicated in WEHI164 cancer cells after exposure to chitosan-coated nanocomposites. Chitosan-coated nanocomposites promoted dendritic cell maturation by inducing the release of interleukin-6 proinflammatory cytokines. According to the results and ancillary studies, superparamagnetic nanoparticles coated with chitosan can be considered an effective and promising treatment for the destruction of cancer cells.
Graphical Abstract

Summary: Chitosan decorated cobalt zinc ferrite nanoferrofluid composites was fabricated for potential cancer hyperthermia therapy with high biocompatibility.
Effect of high temperature annealing on the microstructure evolution and hardness behavior of the Inconel 625 superalloy additively manufactured by laser powder bed fusion
Authors: Dubiel Beata , Gola Kewin , Staroń Sylwia , Pasiowiec Hubert , Indyka Paulina , Gajewska Marta , Zubko Maciej , Kalemba-Rec Izabela , Moskalewicz Tomasz , Kąc Sławomir 
Published: October 2023

Abstract
Additive manufacturing of Inconel 625 components attracts great interest due to its ability to produce parts with complex geometries that are needed for high-temperature applications in the aerospace, energy, automotive and chemical industries. To take full advantage of the potential of additive manufacturing, an in-depth understanding of the effects of prolonged high-temperature annealing on microstructure and hardness evolution is needed. Previous research in this field has mainly focused on a limited range of temperature and time. This study aims to determine the effect of prolonged high-temperature annealing on the evolution of intermetallic phases and carbides, as well as changes in the dislocation substructure of Inconel 625 superalloy additively manufactured by laser powder bed fusion subjected to stress relief annealing and subsequent isothermal annealing at a temperature up to 800 °C for 5–500 h. The microstructure development is correlated with hardness behaviour. It is determined that the microstructure evolution proceeds in four stages with temperature and time increase. In the initial stress-relieved condition, a cellular microstructure with nano-sized precipitates of the Laves phase and NbC carbides at the cell walls occurs, and hardness is equal to 300 HV10. In the 1st stage of the microstructure evolution, the γ'' phase particles precipitate on the cell walls, which results in hardening up to 383 HV10 in the specimen annealed at 700 °C for 5 h. The 2nd stage involves the precipitation of the γ'' phase both on the cell walls and inside the cells, as well as the formation of dislocation networks, which contribute to the softening effect and hardness drop to 319 HV10. In the 3rd stage, at temperature 700 and 800 °C, the δ phase, M23C6 carbides, and the Laves phase precipitate and grow, and the subgrain boundaries are formed. The hardness is in the range of 340–350 HV10 and is higher than in the 2nd stage. In the 4th stage, as the annealing time is increased at a temperature of 800 °C, the δ phase and M23C6 carbides coagulate, and the Laves phase particles spheroidize or partially dissolve. Very intense precipitation and growth of the hard δ phase particles provide an increase in hardness to 402 HV10. As a result of systematic studies, the various strengthening and softening mechanisms acting during high-temperature annealing are determined.

Graphical abstract
Hepatitis B virus–associated diffuse large B cell lymphoma: epidemiology, biology, clinical features and HBV reactivation
Authors: Jiayu Zhu , Zhang Qingyuan 
Published: October 2023

AbstractDiffuse large B cell lymphoma (DLBCL) is the most common type of lymphoma in adults with high heterogeneity. Recent studies have manifested that the occurrence and development of DLBCL is related to hepatitis B virus (HBV) infection. As a medium-to-high prevalence area of HBV infection in China, the importance and exact mechanism of HBV infection in the occurrence of DLBCL have attracted considerable attention. HBV-associated DLBCL has unique clinical characteristics, poor treatment effect and inferior prognosis. HBV reactivation caused by DLBCL treatment also needs for constant vigilance. In this review we summarize the current research progress in the epidemiology, pathogenesis, clinical characteristics, HBV reactivation and antiviral therapies of HBV-associated DLBCL, in order to provide reference for clinical diagnosis and treatment.
State of the art review on the production and bond behaviour of reinforced geopolymer concrete
Authors: Cui Yifei , Ai Weixia , Tekle Biruk Hailu , Liu Menghua , Qu Shihao , Zhang Peng 
Published: October 2023

AbstractGeopolymer is produced through the polymerization of active aluminosilicate material with an alkaline activator, leading to the formation of a green, inorganic polymer binder. Geopolymer concrete (GPC) has become a promising low-carbon alternative to traditional Portland cement-based concrete (OPC). GPC-bonded reinforcing bars offer a promising alternative for concrete structures, boasting excellent geopolymer binder/reinforcement bonding and superior corrosion and high-temperature resistance compared to Portland cement. However, due to differences in the production process of GPC, there are distinct engineering property variations, including bonding characteristics. This literature review provides an examination of the manufacturing procedures of GPC, encompassing source materials, mix design, curing regimes, and other factors directly influencing concrete properties. Additionally, it delves into the bond mechanism, bond tests, and corresponding results that represent the bond characteristics. The main conclusions are that GPC generally has superior mechanical properties and bond performance compared to ordinary Portland cement concrete (OPC). However, proper standardization is needed for its production and performance tests to limit the contradictory results in the lab and on site.
Analysis of the Medical Consequences of Global Terrorist Attacks in Turkic States in the Last 50 Years by Weapon and Attack Type
Authors: Çalışkan Cüneyt , Dağ Nihal , Kınık Kerem 
Published: October 2023

AbstractObjective:This research aimed to conduct an epidemiological analysis of the terrorist attacks, which took place in the Turkic states between 1970 and 2019, and their medical consequences in terms of weapons and attack types. The data collected from this research will be valuable for the development of preventive systems against attacks on Turkic states and offer insights on how to effectively prepare for potential future attacks.Methods:The population of the research consisted of the weapons and types of attacks of the terrorist attacks in the Turkic states drawn from the Global Terrorism Database provided free of charge by START. The number of deaths, injuries, property damage, primary weapons, and types of attacks were analyzed by country.Results:Between 1970 and 2019, 4629 terrorist incidents occurred and 7496 people lost their lives and 10 928 people were injured. Among the types of weapons, the number of people who lost their lives was mostly in firearms, whereas the number of the injured was mostly in explosive weapons. Among the types of attacks, the number of people who lost their lives was mostly observed in the armed attack, whereas the injuries occurred mostly in the bombing attacks. Among the Turkic states, Turkey is the country most affected in terms of medical outcomes.Conclusion:The terrorist attacks in the Turkic states reached their maximum number in the last 10 years. It is predicted that this number will increase further in the next years and affect more people medically.
Mikhuspa Ukyaspa Ima Tinkuyku: Food and Drinks as Mediators of Encounters in Andean Festivals
Authors: Tello Barreda Carlos A. 
Published: October 2023

AbstractMikhuspa ukyaspa ima tinkuyku is Quechua for “eating and drinking, we encounter one another.” Food and drinks have historically been important mediators in the development and renewal of relationships of reciprocity in the Andean region. This article demonstrates how contemporary Andean people continue to use food and drinks to mediate encounters where knowledge transmission and community building take place. In particular, the article explains how members of a dance troupe in Cusco, Peru, use food and drinks to integrate its new members into the dance troupe, teach them the traditions of the group, and explore and (re)define their relationships of reciprocity. By sharing food and drinks, dancers connect their Quechua heritage with their lived experiences to explore and (re)shape their own identities. The article employs a research methodology that centers local epistemology, particularly the Quechua concept of tinkuy, defined as an encounter of different elements that creates something new.
Microplastics: A threat for developing and repairing organs?
Authors: Hofstede Lars T. , Vasse Gwenda F. , Melgert Barbro N. 
Published: October 2023

Abstract
Plastic production has greatly increased in the past decades and has become central to modern human life. Realization is dawning that plastics break down into smaller pieces resulting in micro- or nanoplastics (MNP) that can enter humans directly via the environment. Indeed, MNP have been detected in every part of the human body, including the placenta, which is concerning for development. Early developmental stages are crucial for proper growth and genome programming. Environmental disruptors in MNP can have detrimental effects during this critical window as well and can increase the risk of developing disease and dysfunction. In addition, MNP may impact situations in which developmental pathways are reactivated after birth such as during organ repair. Currently, there is no overview of how MNP can impair (human) development and repair. Therefore, we provide an extensive overview of available evidence on MNP impacting developmental and regenerative processes in various organs in humans and rodent models. In addition, we have included the impact of some additives that can leach from these MNP. We conclude that MNP and their additives can have modulating effects on developing and regenerating organs.
Resolving Debates about Scientific Realism: The Challenge from Stances
Authors: Chakravartty Anjan 
Published: October 2023

AbstractEpistemic stances are collections of attitudes, values, aims, and policies relevant to assessing evidence, eventuating in belief or agnosticism regarding the output of scientific investigations. If, in some cases, conflicting stances promoting scientific realism and antirealism, respectively, are rationally permissible, this would seem to undermine the possibility of resolving certain debates between realists and antirealists. In this article I reply to two concerns about this conception of stances, to the effect that: (1) a stance underlying realism is, in fact, rationally obligatory for realists, given certain natural assumptions; and (2) this sort of permissivism would validate pseudoscience and science denialism.
The Importance of Breaking Even: How Local and Aggregate Returns Make Politically Feasible Policies
Authors: Gerber Alan S. , Huber Gregory A. , Tucker Patrick D. , Cho John J. 
Published: October 2023

AbstractPolicies that promote the common good may be politically infeasible if legislators representing ‘losing’ constituencies are punished for failing to promote their district's welfare. We investigate how varying the local and aggregate returns to a policy affects voter support for their incumbent. In our first study, we find that an incumbent who favours a welfare-enhancing policy enjoys a discontinuous jump in support when their district moves from losing to at least breaking even, while the additional incremental political returns for the district doing better than breaking even are modest. This feature of voter response, which we replicate, has significant implications for legislative politics generally and, in particular, how to construct politically feasible social welfare-enhancing policies. In a second study, we investigate the robustness of this finding in a competitive environment in which a challenger can call attention to a legislator's absolute and relative performance in delivering resources to their district.
Anti-Toxoplasma gondii screening of MMV pandemic response box and evaluation of RWJ-67657 efficacy in chronically infected mice
Authors: dos Santos Bruna Ramos , Ramos Amanda Bruno da Silva Bellini , de Menezes Renata Priscila Barros , Scotti Marcus Tullius , Colombo Fábio Antônio , Marques Marcos José , Reimão Juliana Quero 
Published: October 2023

AbstractToxoplasmosis is a significant public health concern with limited therapeutic options. The medicines for malaria venture (MMV) developed the pandemic response box (PRB) containing 400 drug-like molecules with broad pathogen activity. The aim of this work is to evaluate PRB compounds for their anti-Toxoplasma gondii activity and identify promising candidates for further evaluation. Screening identified 42 selective compounds with half effective concentration (EC50) ranging from 2.4 to 913.1 nm and half cytotoxic concentration (CC50) ranging from 6 μm to >50 μm. Selectivity index (SI) values (CC50/EC50) ranged from 11 to 17 708. Based on its in silico and in vitro profile and its commercial availability, RWJ-67657 was selected for further studies. Molecular docking analysis showed RWJ-67657 is predicted to bind to T. gondii p38 mitogen-activated protein kinase (TgMAPK). Oral administration of RWJ-67657 (20 mg kg day−1/10 days) significantly reduced parasite burden in chronically infected mice compared to mock-treated group (P < 0.01). These findings highlight the PRB as a promising source for anti-T. gondii compounds, with several showing favourable drug properties, including MMV1634492, MMV002731, MMV1634491, MMV1581551, MMV011565, MMV1581558, MMV1578577, MMV233495 and MMV1580482, firstly described here as anti-T. gondii agents. RWJ-67657 emerges as a valuable drug candidate for experimental chronic cerebral toxoplasmosis therapy.