bluuebunny/crossref_metadata_2025_split huggingface dataset:
Managing difference: Preliminary research to an enculturational care strategy in the triple periphery of Eastern Saxony, Lower Silesia and North-Eastern Bohemia
Authors: Vogt Matthias Theodor 
Published: November 2023

There may be areas in the world where reflection on strengthening intercultural resilience belongs to the group of amenities–nice to have, but not a must be, and a mere object of evening chit-chat among well-mannered people, after which the brave citizen goes to bed. The triple periphery of East Saxony, Lower Silesia and North-East Bohemia does NOT belong to this type of area. Here, on the contrary, the future of society and its economy, depends on successful intercultural resilience, and not least its political including its party-political preferences.
For the following reflections, we choose the example of the care labour market and focus in particular on the situation in the German part of the European City of Görlitz-Zgorzelec as pars pro toto of the three-countries’-region. A small preliminary empirical study by Monique Ritter commissioned by us can be found in the same volume.
The intercultural integration of care workers from overseas requires special efforts. Max Frisch (1965) wrote about the situation of Italian “guest workers” in Switzerland: They have called for labour, and human beings are coming. This sentence has a special truth when it comes to people who come from far away and hope to find a new home here.
A critical question to be asked in the following is whether the city of Görlitz is at all suitable for such a project, and how the research can do justice to the complex situation in the border triangle. Can the findings from Leipzig (Decker et al., 2023) be transferred one-to-one to the situation in Görlitz? What insights does a more detailed analysis of crime and constitutional protection statistics offer for the safety of foreign trainees in Görlitz? What is the need for research on enculturation? This article concentrates on the background picture from which the concrete research on care will start.
La desconfianza en los partidos políticos y la percepción ciudadana de desempeño gubernamental: México ante América Latina
Authors: Palazuelos Covarrubias Israel 
Published: November 2023

El objetivo de este trabajo es hacer una revisión transversal del fenómeno de la desconfianza en los partidos políticos en México e indagar sobre su relación con la percepción de desempeño gubernamental. Se pretende tener una perspectiva comparada con los otros 17 países de América Latina ubicando al país en la Región y observando a qué países es más parecido y de cuáles es más distinto.Palabras clave: Desconfianza, partidos políticos, desempeño gubernamental, opinión pública, México, América Latina.
La teoría espacial del voto: una propuesta de aplicación en Latinoamérica
Authors: León Ganatios Luis Eduardo 
Published: November 2023

A partir de una revisión teórica sobre los modelos de proximidad y de direccionalidad, correspondientes a la teoría espacial de voto, se establece la aplicabilidad de los mismos en Latinoamérica y qué modelo debe aplicarse en cada país estudiado con base en criterios establecidos por la misma teoría, tales como el índice de fragmentación, número efectivo de partidos, índice de volatilidad e índice de polarización, para establecer un criterio alternativo que ayude a entender la intención de voto de los electores dentro de los procesos electorales de la región.Palabras clave: teoría espacial del voto, Latinoamérica, modelo de proximidad, modelo direccional, “issues”.
El Partido de la Revolución Democrática en el Senado de la República: Análisis del éxito de sus iniciativas 2000-2012
Authors: Cortez Salinas Josafat , Salazar Rebolledo Grisel 
Published: November 2023

El trabajo analiza al Partido de la Revolución Democrática (PRD) en el Senado de la Republica durante el periodo 2000-2012 para comprender el comportamiento de la izquierda en su faceta parlamentaria bajo la nueva dinámica legislativa en México. Buscamos explicar los factores que facilitan la aprobación de las iniciativas presentadas con las premisas básicas de la teoría de la elección racional para estudios congresionales. Se sostiene que un partido político tendrá más posibilidades de tener éxito en sus iniciativas de ley cuando cuente con mayores capacidades dentro de la Cámara, en términos de negociación y expertice técnica. Encontramos que en el caso del PRD existe una relación entre la presidencia de comisiones, la temática de las iniciativas vinculada a la ideología partidista, la relevancia de los temas dada por la coyuntura política.Palabras clave: Partido de la Revolución Democrática, Proceso legislativo, Senado en México.
A vueltas con las ONG: Perspectivas teóricas sobre su papel en el proceso político
Authors: Muñoz Márquez Luz M. 
Published: November 2023

El escaso diálogo entre perspectivas teóricas complica un análisis sistemático sobre el papel de las ONG en el proceso político y más en concreto en las políticas públicas. El objetivo de este artículo es hacer una revisión de los diferentes enfoques sobre las ONG utilizados en la ciencia política y señalar algunas de las consecuencias de la fragmentación teórica. Se constata que las perspectivas de la sociedad civil, tercer sector, movimientos sociales y grupos de interés analizan esencialmente el mismo fenómeno: la acción colectiva a través de organizaciones de ciudadanos que defienden una causa concreta pero centrándose en diferentes aspectos de su función en el proceso político y en la definición de las políticas. Finalmente, se propone una definición operativa de las ONG a partir de los enfoques analizados.Palabras clave: ONG, sociedad civil, movimientos sociales, tercer sector, grupos de interés y políticas públicas.
Entendimiento Comunicativo de Niklas Luhmann, y Acción Comunicativa de Jürgen Habermas: Aportaciones en la teoria organizacional
Authors: Pont Vidal Josep 
Published: November 2023

Describimos los conceptos centrales que configuran el paradigma entendimiento comunicativo de Niklas Luhmann, y la acción comunicativa de Jürgen Habermas, y su posibilidad de utilización en la teoría organizacional. La teoría de sistemas autorreferenciales manifiesta limitaciones al relegar aspectos antropológicos y ontológicos y situar al ser humano en el entorno del sistema. Como posibilidad de superar las limitaciones que aparecen en la teoría de sistemas autorreferenciales respecto a la inclusión antropológica, proponemos la idea de “autopoiesis reflexiva” y su utilización en las observaciones en la observación de las organizaciones e instituciones.Palabras clave: acción comunicativa; entendimiento comunicativo; autopoiesis; administración pública; metodología.
Rendimientos crecientes, trayectorias dependientes y el estudio de la política
Authors: Pierson Paul , Arcos Robledo Traductor: Héctor Sebastián 
Published: November 2023

Es cada vez más común para los científicos sociales describir el proceso político como una “trayectoria dependiente” (path dependence). Sin embargo, a menudo el concepto es empleado sin una elaboración cuidadosa. Este artículo conceptualiza la trayectoria dependiente como un proceso social basado en una dinámica de “rendimientos crecientes”. Examinando la literatura reciente de la economía y sugiriendo su extensión al mundo de la política, el artículo demuestra que los procesos de rendimientos crecientes son claramente valiosos y que existen buenos fundamentos analíticos para explorar sus causas y consecuencias. La investigación de los rendimientos crecientes puede proporcionar un marco más riguroso para el desarrollo de algunas de las afirmaciones clave de la investigación reciente en el institucionalismo histórico, a saber: la importancia de los patrones específicos de tiempo y secuencia; una amplia gama de resultados sociales puede ser posible; grandes consecuencias pueden resultar de acontecimientos relativamente pequeños o contingentes; particulares cursos de acción, una vez introducidos, pueden ser casi imposibles de revertir; y, consecuentemente, el desarrollo político está marcado por momentos o coyunturas que configuran los contornos básicos de la vida social.Palabras clave: trayectorias de dependencia, rendimientos crecientes, desarrollo político, acción colectiva, instituciones.
Elecciones, miedo y democracia en México. Autoritarismo y violencia política
Authors: Vargas González Fernando 
Published: November 2023

El objetivo de este trabajo es analizar los elementos simbólicos y materiales de la etapa electoral a través de casos y hechos de uso de estrategias de violencia política que afectaron el libre ejercicio de los derechos ciudadanos, como se reflejó en 2018 en la elección más violenta del país. Dentro del proceso de consolidación política inconclusa en México, la violencia política, que se expresa en diferentes formas y modalidades, erosiona la confianza y la gobernabilidad, y es un signo de riesgo para la consolidación de la democracia.Palabras clave: Democracia, Violencia política, Elecciones en México, Consolidación democrática, odio político Abstract The purpose of this paper is to analyze the symbolic and material elements of the electoral stage through cases and facts of political violence strategies that affected the free exercise of citizens’ rights, as reflected in 2018 in the most violent election of the country. Within the process of unfinished political consolidation in Mexico, political violence, expressed in different forms and modalities, erodes trust and governability, and is a sign of risk for the consolidation of democracy.Key words: Democracy, Political violence, Elections in Mexico, Democratic consolidation, political hatred
A Network Model of the Modulation of γ Oscillations by NMDA Receptors in Cerebral Cortex
Authors: Susin Eduarda , Destexhe Alain 
Published: November 2023

AbstractPsychotic drugs such as ketamine induce symptoms close to schizophrenia and stimulate the production of γ oscillations, as also seen in patients, but the underlying mechanisms are still unclear. Here, we have used computational models of cortical networks generating γ oscillations, and have integrated the action of drugs such as ketamine to partially block NMDA receptors (NMDARs). The model can reproduce the paradoxical increase of γ oscillations by NMDA receptor antagonists, assuming that antagonists affect NMDA receptors with higher affinity on inhibitory interneurons. We next used the model to compare the responsiveness of the network to external stimuli, and found that when NMDA channels are blocked, an increase of γ power is observed altogether with an increase of network responsiveness. However, this responsiveness increase applies not only to γ states, but also to asynchronous states with no apparent γ. We conclude that NMDA antagonists induce an increased excitability state, which may or may not produce γ oscillations, but the response to external inputs is exacerbated, which may explain phenomena such as altered perception or hallucinations.
Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
Authors: Micheva Kristina D. , Gong Belvin , Collman Forrest , Weinberg Richard J. , Smith Stephen J. , Trimmer James S. , Murray Karl D. 
Published: November 2023

AbstractAntibody (Ab)-based imaging techniques rely on reagents whose performance may be application specific. Because commercial antibodies are validated for only a few purposes, users interested in other applications may have to perform extensive in-house antibody testing. Here, we present a novel application-specific proxy screening step to efficiently identify candidate antibodies for array tomography (AT), a serial section volume microscopy technique for high-dimensional quantitative analysis of the cellular proteome. To identify antibodies suitable for AT-based analysis of synapses in mammalian brain, we introduce a heterologous cell-based assay that simulates characteristic features of AT, such as chemical fixation and resin embedding that are likely to influence antibody binding. The assay was included into an initial screening strategy to generate monoclonal antibodies that can be used for AT. This approach simplifies the screening of candidate antibodies and has high predictive value for identifying antibodies suitable for AT analyses. In addition, we have created a comprehensive database of AT-validated antibodies with a neuroscience focus and show that these antibodies have a high likelihood of success for postembedding applications in general, including immunogold electron microscopy. The generation of a large and growing toolbox of AT-compatible antibodies will further enhance the value of this imaging technique.
Real‐time analysis of the cancer genome and fragmentome from plasma and urine cell‐free DNA using nanopore sequencing
Authors: van der Pol Ymke , Tantyo Normastuti Adhini , Evander Nils , Hentschel Anouk E , Wever Birgit MM , Ramaker Jip , Bootsma Sanne , Fransen Marieke F , Lenos Kristiaan J , Vermeulen Louis , Schneiders Famke L , Bahce Idris , Nieuwenhuijzen Jakko A , Steenbergen Renske DM , Pegtel D Michiel , Moldovan Norbert , Mouliere Florent 
Published: November 2023

AbstractCell‐free DNA (cfDNA) can be isolated and sequenced from blood and/or urine of cancer patients. Conventional short‐read sequencing lacks deployability and speed and can be biased for short cfDNA fragments. Here, we demonstrate that with Oxford Nanopore Technologies (ONT) sequencing we can achieve delivery of genomic and fragmentomic data from liquid biopsies. Copy number aberrations and cfDNA fragmentation patterns can be determined in less than 24 h from sample collection. The tumor‐derived cfDNA fraction calculated from plasma of lung cancer patients and urine of bladder cancer patients was highly correlated (R = 0.98) with the tumor fraction calculated from short‐read sequencing of the same samples. cfDNA size profile, fragmentation patterns, fragment‐end composition, and nucleosome profiling near transcription start sites in plasma and urine exhibited the typical cfDNA features. Additionally, a high proportion of long tumor‐derived cfDNA fragments (> 300 bp) are recovered in plasma and urine using ONT sequencing. ONT sequencing is a cost‐effective, fast, and deployable approach for obtaining genomic and fragmentomic results from liquid biopsies, allowing the analysis of previously understudied cfDNA populations.
ОЦІНКА ЕФЕКТИВНОСТІ ІННОВАЦІЙНИХ ПІДХОДІВ У ФОРМУВАННІ ФАХОВОЇ КОМПЕТЕНТНОСТІ ВЧИТЕЛІВ МУЗИЧНОГО МИСТЕЦТВА
Authors: SHYMAN IRYNA 
Published: November 2023

Автор досліджує проблему ефективності інноваційних підходів у формуванні фахової компетентності вчителів музичного мистецтва, що безпосередньо позначається на їх педагогічній діяльності. Наголошується на тому, які саме компетентності мають бути притаманні вчителям музичного мистецтва; робиться акцент на загальноосвітніх компетентностях.
У статті здійснений аналіз застосування інноваційних підходів у формуванні фахової компетентності вчителів музичного мистецтва; охарактеризовано роботи вчених, котрі досліджували дане питання; виокремлено перспективи подальших напрацювань автора.
Association of Predisposing Factors of Diabetes with six Stages of Disease Progression in Ayurveda (Shatkriyakala): A Cross-Sectional Pilot Study
Authors: Sharma Meenakshi , Nayak AP , Mandal Sisir Kumar , Rai Shalini , More Anand 
Published: November 2023

Introduction: Diabetes has emerged as a global health crisis. It not only causes morbidity and mortality figures but deteriorates quality of life, national productivity and economic burden too. Besides this, no major advancement has been made for early diagnosis and prevention of diabetes. Clinical Staging of morbidity has been depicted in classical texts of Ayurveda modelled on pathogenesis.) This type of classification can serve as the basis of levelled and precise preventive interventions. Thus, identification of cases pertaining to each stage of pathogenesis based on validated parameters is a prerequisite. This research is a preliminary work on validation of clinical staging. This Ayurveda system of staging method can serve as a holistic model of prevention as it includes variable responsible host factors, etiology, risk factor stratification and grading of pathological state. Aim: The present study aimed to explore the six stage pathogonomic model SKK (Shat kriyakala and its relevance in tracking pathogenesis at preclinical stages. Materials and methods: A cross-sectional trial was conducted in forty- two subjects. Study participants were subjected to a questionnaire (Q2) to assess clinical features in latent and clinical stages of Prameha (~ Diabetes Mellitus) and biomarkers (CRP and Serum cortisol).Result: The mean score of SKK questionnaire was found maximum with the corresponding stages designed on the basis of predisposing factors and laboratory parameters.Conclusion: It can be inferred from the study that SKK may act as a tool to check pathogenesis at an early stage. The model may act as a potential paradigm for preventing diabetes risk as well as preventive care from a public health perspective.
Factors Associated With Actionable Gastrointestinal Panel Results in Hospitalized Children
Authors: Ho Erin C. , Cotter Jillian M. , Thomas Jacob , Birkholz Meghan , Dominguez Samuel R. 
Published: November 2023

OBJECTIVES
There is uncertainty regarding which hospitalized patients with acute gastroenteritis (AGE) benefit from gastrointestinal panel (GIP) testing. Unnecessary testing may lead to increased costs, overdiagnosis, and overtreatment. In general, AGE management and outcomes are most impacted if an actionable (bacterial or parasitic) result is obtained. We aimed to assess which clinical reasons for ordering GIP testing (“order indications”) and patient factors were associated with actionable results.

METHODS
This is a cross-sectional study of pediatric patients hospitalized between 2015 and 2018 at a large pediatric health care system with diarrhea and a GIP performed. Multivariable regression analysis was used to determine associations between actionable GIP results and order indication, stool frequency, and demographics. Findings were evaluated in patients with complex chronic conditions (CCC) and non-CCC patients.

RESULTS
There were 1124 GIPs performed in 967 encounters. Non-CCC patients had more actionable results than CCC patients, and reasons for testing differed. Across both cohorts, age ≥1 year old was positively associated with actionable results. For non-CCC patients, actionable results were associated with “diarrhea with blood or pus” order indication and nonwinter season; international travel was associated with non-Clostridioides difficile bacteria and parasites. No order indications were associated with actionable results for CCC patients.

CONCLUSIONS
Patient factors and order indications that may help identify children hospitalized for AGE with actionable GIP results include older age (regardless of CCC status), as well as bloody stools and international travel in previously healthy children. Prospective validation of these findings could help improve diagnostic stewardship and decrease unnecessary testing.
Composition of gut microbiota and its correlations with neurological, intestinal, cardiovascular and metabolic diseases
Authors: Sciuto Morena , Catanzaro Roberto 
Published: November 2023

AbstractThe intestinal microbiota is a microenvironment that has been the subject of studies for several decades. Over time, it has been reconsidered as a possible cofactor of multiple acute and chronic human diseases. In fact, alterations of the intestinal bacterial flora have been found in various neurological diseases. There are three modes of interaction between the intestinal microbiota and the gut-brain-axis: chemical signals, neural pathways and immune system. Even at the gastrointestinal level, the gut microbiota plays certainly an important role in the etiopathogenesis of chronic intestinal inflammatory diseases but also in irritable bowel syndrome. An important correlation has also been demonstrated with non-alcoholic fatty liver disease, as well as in other metabolic, cardiovascular and oncological diseases. Bacteria, viruses, fungi and various microorganisms that normally reside in our intestines can also be called into question as protective factors against these diseases. All this evidence leads researchers to consider the gut microbiota as a key element in the determination of aforementioned diseases. Therefore, it would be foreseeable in the future to associate the use of probiotics with the therapies used in the treatment of all these diseases. In this review we have condensed the main current knowledge regarding the link between the most frequent diseases and the gut microbiota.
Effect of microencapsulation conditions on phenolic compounds and antioxidant activity of propolis using double emulsion solvent evaporation approach
Authors: Amrane S. , Chaalal M. , Bouriche S. , Ydjedd S. , Rezgui F. , Ouchemoukh S. 
Published: November 2023

AbstractThe aim of this work was to microencapsulate propolis phenolic compounds using polycaprolactone as wall material by double emulsion solvent evaporation (w1/o/w2). Microencapsulation experiments were carried out by investigating the effect of sample/solvent ratio (10–100 mg mL−1), poly(ε-caprolactone) (PCL) concentrations (200–1,000 mg mL−1), poly(vinyl alcohol) (PVA) concentrations (0.5–2.5 g mL−1), and stirring speed (200–1,000 r.p.m.) on the microencapsulation efficiency of total phenolic content (TPC%) and antioxidant activity of propolis. The best microencapsulation conditions were selected according to the total phenolic amount and their antioxidant activity. Experimental results showed that all microencapsulation conditions had significant effects (P < 0.05) on total phenolic content and antioxidant activities. The best conditions were: 30 mg mL−1, 600 mg mL−1, 2 g mL−1, and 400 r.p.m. for sample/solvent ratio, PCL concentrations, PVA concentrations, and stirring speed, respectively, with values of 86.98 ± 0.03% for phenolic encapsulation efficiency, 53.81 ± 0.50% for free radical scavenging activity (DPPH), and 45,480 Trolox equivalent, mg TE/100 g dry weight for ferric reducing antioxidant power (FRAP). Under all encapsulation conditions, a significant positive correlation was observed between ferric reducing antioxidant power, free radical scavenging activity, and phenolic content.