bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using cGANs for Anomaly Detection: Identifying Astronomical Anomalies in JWST Imaging
Authors: Pearce-Casey Ruby , Dickinson Hugh , Serjeant Stephen , Bromley Jane 
Published: October 2023

Abstract
We present a proof of concept for mining JWST imaging data for anomalous galaxy populations using a conditional Generative Adversarial Network (cGAN). We train our model to predict long wavelength NIRcam fluxes (LW: F277W, F356W, F444W between 2.4 and 5.0 μm) from short wavelength fluxes (SW: F115W, F150W, F200W between 0.6 and 2.3 μm) in ∼2000 galaxies. We test the cGAN on a population of 37 Extremely Red Objects (EROs) discovered by the CEERS JWST Team. Despite their red long wavelength colors, the EROs have blue short wavelength colors (F150W − F200W ∼ 0 mag) indicative of bimodal SEDs. Surprisingly, given their unusual SEDs, we find that the cGAN accurately predicts the LW NIRcam fluxes of the EROs. However, it fails to predict LW fluxes for other rare astronomical objects, such as a merger between two galaxies, suggesting that the cGAN can be used to detect some anomalies. (The source code and trained model (Pearce-Casey 2023) are available at https://github.com/RubyPC/Anomaly_Detection_with_cGANs.)
Results of Polarimetric Observations of Near-Earth Asteroid 433 Eros
Authors: Petrov Dmitry , Zhuzhulina Elena 
Published: October 2023

Abstract
Near-Earth asteroids are of great importance for science. We present the results of polarimetric observations of near-Earth asteroid 433 Eros. Previous polarimetric observations of this asteroid did not cover a range of phase angles less than 9°. We were able to measure the degree of linear polarization of asteroid 433 Eros at a phase angle ≈4.°8. The data obtained made it possible to determine the parameters of the negative branch of the degree of linear polarization of this asteroid, such as the magnitude and position of the polarization minimum in four spectral ranges.
La cybercriminalité, criminalité sans frontière
Authors: Watin-Augouard Marc 
Published: October 2023

La cybercriminalité connaît une croissance inquiétante en raison du comportement des prédateurs qui bénéficient d’un rapport gain/risque pénal nettement plus favorable que celui qui s’attache à la criminalité classique. En outre, les délinquants profitent de l’effet de frontière qui est un obstacle pour les Etats en raison de la limitation territoriale de leur souveraineté et donc de leur capacité à agir contre des auteurs agissant depuis l’étranger. La coopération internationale se développe par le biais notamment de la Convention de Budapest, mais se heurte au fait que les États « cybervoyous » sont précisément ceux qui ne l’ont pas ratifiée. De son côté, l’Union européenne a pour ambition de hisser le niveau de cybersécurité des États membres. Le dernier règlement e-Evidence facilite un accès rapide aux preuves numériques qui conditionne le succès des enquêtes.
Filling the Gaps: Evaluation of an Online Continuing Professional Development Program for Australian Registered Nurses to Build Capacity to Care for People With Developmental Disability
Authors: Cashin Andrew , Pracilio Amy , Buckley Thomas , Trollor Julian N. , Wilson Nathan J. 
Published: October 2023

Background:
People with autism spectrum disorder and/or intellectual disability have some of the worst health outcomes of any population group. Internationally, it has been identified that RNs are not adequately prepared to provide care to these groups through mainstream health care services.

Method:
A cross-sectional online evaluation survey of participants who completed learning to build the capacity of RNs to care for people with autism spectrum disorder and/or intellectual disability was conducted.

Results:
The learning site was found to be easily accessible and engaging, and it facilitated knowledge construction. A statistically significant increase in self-reported comfort, confidence, and preparedness compared with the sample of RNs in a national survey conducted before the site launch was identified.

Conclusion:

This online continuing professional development program facilitated RNs' perceived comfort, confidence, and preparedness to care for people with autism spectrum disorder and/or intellectual disability. Findings suggest the merit of high-quality online continuing professional development programs to fill this educational gap.

[
J Contin Educ Nurs.
2023;54(12):554–560.]
La narration est-elle un genre de l’activité verbale au travail ?
Authors: Boutet Josiane 
Published: October 2023

Dans cet article je m’interroge sur la présence du genre de la narration dans la vie verbale au travail. Le couplage entre l’activité de travail et l’activité de langage s’inscrit dans une histoire longue : j’évoquerai les décennies de l’industrialisation (xixe siècle – milieu du xxe siècle) qui se sont caractérisées par l’interdiction de toute activité verbale durant l’activité de travail ; a fortiori par l’éviction de la narration. Depuis le premier choc pétrolier de 1973 et la disparition progressive du modèle taylorien, d’autres modes d’organisation du travail se sont mis en place qui ont reconnu et valorisé la part langagière du travail : mais qu’en est-il du récit ? En analysant différentes situations de travail, je montrerai comment un ensemble de déterminants organisationnels, sociaux ou écologiques viennent empêcher ou contraindre le développement d’une activité narrative. Lorsqu’on observe une activité narrative orale, elle peut avoir comme énonciateurs des salariés comme des clients ou demandeurs. Il en va de même des narrations écrites qui possèdent souvent une fonction de contrôle de l’activité des salariés.
Mouse Memory CD8 T Cell Subsets Defined by Tissue-Resident Memory Integrin Expression Exhibit Distinct Metabolic Profiles
Authors: Sportiello Mike , Poindexter Alexis , Reilly Emma C , Geber Adam , Lambert Emo Kris , Jones Taylor N , Topham David J 
Published: October 2023

Abstract
Tissue-resident memory CD8 T cells (TRM) principally reside in peripheral nonlymphoid tissues, such as lung and skin, and confer protection against a variety of illnesses ranging from infections to cancers. The functions of different memory CD8 T cell subsets have been linked with distinct metabolic pathways and differ from other CD8 T cell subsets. For example, skin-derived memory T cells undergo fatty acid oxidation and oxidative phosphorylation to a greater degree than circulating memory and naive cells. Lung TRMs defined by the cell-surface expression of integrins exist as distinct subsets that differ in gene expression and function. We hypothesize that TRM subsets with different integrin profiles will use unique metabolic programs. To test this, differential expression and pathway analysis were conducted on RNA sequencing datasets from mouse lung TRMs yielding significant differences related to metabolism. Next, metabolic models were constructed, and the predictions were interrogated using functional metabolite uptake assays. The levels of oxidative phosphorylation, mitochondrial mass, and neutral lipids were measured. Furthermore, to investigate the potential relationships to TRM development, T cell differentiation studies were conducted in vitro with varying concentrations of metabolites. These demonstrated that lipid conditions impact T cell survival, and that glucose concentration impacts the expression of canonical TRM marker CD49a, with no effect on central memory-like T cell marker CCR7. In summary, it is demonstrated that mouse resident memory T cell subsets defined by integrin expression in the lung have unique metabolic profiles, and that nutrient abundance can alter differentiation.
Indigenous knowledge on medicinal plants used by local villagers associated with Sadasivakona—A sacred grove of Chittoor district, Andhra Pradesh, India
Authors: Sivaramakrishna Pasupuleti , Yugandhar Pulicherla , Manjunatha Reddy Yarramreddy 
Published: October 2023

BACKGROUND:
The local villagers residing at Sadasivakona sacred grove are associated with medicinal plants and utilize many medicinal plants to cure ailments. Because of this, the present study was intended to document the traditional uses of medicinal plants used by local villagers residing at Sadasivakona—a sacred grove of Chittoor district, Andhra Pradesh, India.

METHODS:
The documentation of indigenous knowledge on medicinal plants used by local villagers of Sadasivakona sacred grove was carried out with a structured questionnaire. The documentation of indigenous knowledge was made by conducting several tours and personal interviews with their local dialect from 2019 to 2020.

RESULTS:
Sixty-seven potential medicinal plants belonging to 59 genera and 36 families were documented from Sadasivakona—a sacred grove of Chittoor district, Andhra Pradesh, India. For the preparation of medicine, leaves (49%) among the plant parts, paste (36%) among the form of medicine, internal administration (53%) among the intake of medicine, and cough (16%) among the ailment treatment were noticed as the highest percentages. Altogether, 41 types of ailments were successfully documented from the herbal practitioners of Sadasivakona sacred grove.

CONCLUSIONS:
There is no documentation on the indigenous knowledge of local villagers of Sadasivakona sacred grove so far. Hence the present study focuses on the documentation of perishing knowledge of this sacred grove. Among the documented plants, the therapeutic uses of 28 medicinal plants were matched with Dr. Duke’s Phytochemical and Ethnobotanical database and 10 medicinal plants with Foundation for Revitalization of Local Health Traditions database. The documented information may be helpful to the pharmaceutical industries in the preparation of novel drugs.
Assessing the effect of Shodhana (detoxification) process using chromatographic profiling (HPTLC, HPLC, LC-MS, and GC-MS) and estimation of toxic content Abrine in Abrus precatorius L. (Gunja) seeds
Authors: Meena Ajay Kumar , Venktaraman Poorna , Ganji Kusuma , Kumar Neeraj , Singh Ravindra , Dixit Amit Kumar , Ilavarasan R. , Srikanth N , Dhiman Kartar Singh 
Published: October 2023

BACKGROUND AND OBJECTIVE:Abrus precatoriusL. (Gunja) is popular in Ayurveda system of medicine for its seeds, which are toxic because of the presence of Abrine–an alkaloid. It is used for the management of skin disease (Kustha), itching (kandu), cough (kasa), wound (vrana), and alopecia (indralupta). Theshodhanaprocess in Ayurveda is used for the purification and detoxification of toxic plant materials. This study aimed to observe the effect of theshodhana(purification) on phytochemicals and the Abrine content ofA. precatoriusL. (Gunja) seeds.MATERIALS AND METHODS:The ethanolic and chloroform extracts ofA. precatoriusL. (Gunja) seeds are used to determine theRfvalue through high-performance thin-layer liquid chromatography (HPTLC) technique. Chemical profiling of seeds was carried out using sophisticated modern chromatographic different such as HPTLC, high-performance liquid chromatography (HPLC), gas chromatography with mass spectrometry (GC-MS), and liquid chromatography with mass spectrometry (LC-MS).RESULTS:TheRfvalue 0.45 corresponds to Abrine and confirms its presence inGunjaseeds. GC-MS and LC-MS results show the presence of 19–22 compounds. Results of HPLC analysis showed that Abrine content in chloroform extract and ethanol extract reduced to 30.36% and 10.20%, respectively, aftershodhanaprocess.CONCLUSIONS:These results showed the significance and effectiveness ofshodhanaprocess in reducing the toxins present inA. precatorius.
First-order kinetic study-based comparative shelf-life assessment of Raw Vetas (Salix alba L. stem bark) and Vetas Ghana (a semisolid form of Salix alba L. stem bark aqueous extract)
Authors: Verma Ravi , Jain Vipin , Rawat Hemant , Kushwaha Vikram , Gandhi Yashika , Mishra Sujeet K. , Kumar Vijay , Tandon Smriti , Charde Vaibhav , Jagtap Chandrashekar , Babu Gajji , Singh Arjun , Singh Ravindra , Sharma Bhagwan Sahai , Srikanth Narayanam 
Published: October 2023

BACKGROUND:
Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India (API). The aim of this study to evaluate the comparative long-term shelf-life study of Raw Vetas (Salix alba stem bark) and Vetas Ghana (a semisolid form of Salix alba Stem bark aqueous extract).

METHODS:
A stability chamber with environmental conditions 30°C ± 2°C/60% RH ± 5% was used for the long-term shelf-life study of Raw Vetas and Vetas Ghana. Physicochemical parameters like loss on drying, pH, total ash, acid insoluble ash, water extractive value, and alcohol extractive value were evaluated at a regular frequency (0th, 3rd, 6th, 9th, and 12th months).

RESULTS:
There are significant changes that have been observed w.r.t. physicochemical parameters analysis. Physicochemical parameters revealed that the shelf-life of Raw Vetas ranged from 31 to 66 months and the shelf-life of Vetas Ghana ranged from 38 to 62 months.

CONCLUSIONS:
The average shelf-life of Raw Vetas and Vetas Ghana was 41.83 and 47.50 months, respectively. This study may help to understand the shelf-life of various Ayurvedic formulations consisting of Raw Vetas and Vetas Ghana.
Computational modeling and analysis of Ayurvedic compounds in fighting against COVID-19
Authors: Gupta Pramodkumar P. , Nayak Shraddha U. , Parab Mala M. , Dasgupta Debjani , Harit Maheshkumar S. 
Published: October 2023

AIM:
To screen the selective Ayurvedic amalgams against severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) main protease in the investigation of antiviral activity using computational-based methods.

MATERIALS AND METHODS:
The current research study endeavors to gauge the in silico potency of Ayurvedic molecules/drugs, chosen from primeval classical literature and former human medication protocols of Ayurveda for the preemption and treatment of contagion (COVID-19). Overall, 84 Ayurvedic compounds on the basis of antiviral activity were searched from literature and public database sources and canonical smiles format molecular information was retrieved from the PubChem database. All the compounds were sketched using Chemsketch tool and optimized using UFF force field. The selected molecules were then virtually screened against the SARS-CoV-2 main protease available structure.

RESULTS:
The outcomes were evaluated based on docking scores and pharmacophoric-based interactions; five compounds exhibited an optimum interaction within the binding site of SARS-CoV-2 main protease.

CONCLUSION:
The current research study lay the foundation of drug repurposing with the amalgamation of knowledge of Ayurveda and computational aided modeling in fighting against COVID-19. Therefore, the pragmatic dogma proposed here will facilitate learning, generate evidence, and pave the way forward.
Preliminary analysis of Rasayana Vati—A novel herbal medicine
Authors: Rani Renu , Bhinde Sonam Sagar , Kori Virendra Kumar , Patel Kalpana S. , Harisha Channappa Rudrappa , Shukla Vinay J. 
Published: October 2023

BACKGROUND:

Rasayana Vati (RV) is an herbal preparation containing Amalaki (Phyllanthus emblica L.), Haridra (Curcuma longa L.), and Guduchi (Tinospora cordifolia (Willd.) Miers) in an equal proportion. It is a useful formulation in Beejadushtijanya Pandu (thalassemia). Till date, analytical data are not available for this herbal preparation. The present study was aimed to generate analytical data of the RV for its quality assurance.

METHODS:
Pharmacognostical, physicochemical, and high-performance thin-layer chromatography (HPTLC) analysis was carried out at Pharmacognosy and Pharmaceutical laboratory, ITRA, Jamnagar.

RESULTS:
The presence of cork cells, starch grains, parenchymal cells, stone cells, pitted vessels, and collenchyma cells was the characteristic features observed in the microscopy of drug. Physicochemical analysis showed 3.7 kg/cm2 hardness, 0.15% w/w loss on drying, 25.19% w/w water soluble extract, and pH was 6. HPTLC showed five spots at 254 and four spots at 366 nm.

CONCLUSION:
The results of pharmacognostical and pharmaceutical parameters have generated preliminary data, which could be used as fingerprinting of RV for future researchers.
Comparative shelf-life study of Raw Guggulu (Commiphora wightii oleo-gum resin) and Shodhita Guggulu (cow urine processed C. wightii oleo-gum resin)
Authors: Charde Vaibhav , Jagtap Chandrashekar , Kumar Vijay , Kushwaha Vikram , Grewal Jyotika , Mishra Sujeet K. , Shakya Santosh K. , Soni Hemant , Singh Gagandeep , Babu Gajji , Singh Arjun , Singh Ravindra , Khanduri Shruti , Sharma Bhagwan Sahai , Srikanth Narayanam 
Published: October 2023

BACKGROUND:
Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India. The objective of this article is to evaluate and compare the long-term shelf-life study of Raw Guggulu (RG) (C. wightii oleo-gum resin) and Shodhita Guggulu (SG) (cow urine processed C. wightii oleo-gum resin).

MATERIALS AND METHODS:
A stability chamber with environmental conditions 30°C ± 2°C/60% ± 5% RH was used for long-term shelf-life study of RG and SG. Physico-chemical parameters such as loss on drying, pH, total ash, acid-insoluble ash, water extractive value, and alcohol extractive value were tested at regular frequency (0th, 3rd, 6th, 9th, and 12th month).

RESULTS:
Significant changes have been observed w.r.t. analysis of physico-chemical parameters. Physico-chemical parameters revealed that the shelf-life of RG ranged from 42 to 66 months and shelf-life of SG ranged from 39 to 62 months.

CONCLUSION:
The average shelf-life of RG and SG was found out to be 55.16 and 48.16 months, respectively. These studies may help to understand the shelf-life of various ayurvedic formulations of RG and SG.
Ethnic recipes from the tribes of Jawhar and Shahapur forest division
Authors: Gurav Arun Manohar , Kolhe Rasika , Prasad Goli Penchala , Rath Chinmay , Mangal Anupam Kumar , Srikanth Narayanam 
Published: October 2023

BACKGROUND:
Tribals have developed their tradition of the food system by using native plants having nutritional as well as medicinal values. Different parts of wild edible plants are consumed by them in various forms such as curry, pickles, fried, etc. Such knowledge is applied to cope with starvation and survive in unfavorable conditions. But this valuable information is not preserved well by the next generation. Therefore, there is a need to systematically record such unexplored traditional knowledge for further detailed study. Present study aimed to document and record wild edible plants and details of the recipes prepared by the tribal of Jawhar and Shahapur forest division.

METHODS:
A Medico-Ethno Botanical Survey was carried out in Jawhar and Shahapur forest divisions of Maharashtra during the year 2018–19. The study includes the documentation of the traditionally used edible plants by the ethnic group of people in the studied area and is presented systematically.

RESULT:
A total of 34 recipes prepared from 32 different species were described in detail. Out of 32 species, 28 species are wild and only four species are cultivated on the farm or yard. Ten recipes using leaves (fresh and dried), six using fruits, five using flowers, six using tubers (dry and curry of Dioscorea bulbifera L.), four using pods, two using seeds, and one recipe using shoot are reported, which are not familiar in the urban areas. The use of ash for the processing of Dioscorea species to make it more palatable was found as a unique method.

CONCLUSION:
Vegetable recipes of nine species were reported as noteworthy after validating from the available literature. Further investigation of collected data from the perspective of their phytochemical and nutraceutical studies may provide better nutritional and medicinal sources for the future.
DNA bar-coding, pharmacognostical, and phytochemical analysis of Atalantia monophylla DC. leaves
Authors: Nathulal Das Ashokkumar , Acharya Rabinarayan , Rudrappa Harisha C. , Shukla Vinay J. , Hegde Satisha 
Published: October 2023

BACKGROUND:
Leaves of Atalantia monophylla DC. (Syn. Limonia monophylla L.), family Rutaceae, are traditionally used to treat rheumatoid pain, hemiplegia, itch and cutaneous complaints, cough, and as an antidote to snake bite, etc. The present study reports the detailed morphology, anatomy, genetic barcoding, physiochemical, and phytochemical aspects of A. monophylla leaves.

METHODS:
The sample of leaves of the plant were collected from one of its natural habitat, Athagarh forest, Odisha, India. The detailed macroscopic observations were made with naked eyes, and microscopy characters of leaf, stomatal index, and powder microscopy were done as per standard protocol. Physicochemical and qualitative preliminary phytochemical analysis, high-performance thin layer chromatography (HPTLC), and DNA bar-coding studies were carried out as per Ayurvedic Pharmacopoeia of India methods and other standard guidelines.

RESULTS:
Leaves were opposite, unifoliate, ovate-elliptic, entire, emarginate, and glabrous. Transverse section (TS) through petiole showed epidermis, cortex, pericyclic fibers, and vascular bundles along with trichome. TS of lamina passing through midrib shows lamina with upper and lower epidermis, lignified elements, interrupted by stomata and unicellular trichome. Microscopic characteristics of the leaves powder show the presence of oil globule, rhomboidal crystal, prismatic crystal, and fragment of paracytic stomata. The result of loss on drying, total ash, acid-insoluble ash, water, methanol-soluble extractive, and the obtained pH values were about 10.47 ± 0.40%, 6.94 ± 0.95%, 1.00 ± 0.00%, 30.41 ± 2.26%, 7.64 ± 0.56%, and 6.6, respectively. Qualitative phytochemical analysis shows the presence of carbohydrates, glycosides, saponins, alkaloids, tannins, and flavonoids and the HPTLC study revealed 29 spots at both short (254 nm) and long (366 nm) ultraviolet rays.

CONCLUSION:
Epidermal cells, oil globule, rhomboidal crystal, prismatic crystal, paracytic stomata, and simple unicellular trichome are key characters for identification of its leaves. The results obtained from pharmacognostical, phytochemical, physicochemical, and DNA bar-coding studies may serve as the diagnostic tool of A. monophylla toward its authentication and identification and also in maintaining of quality, strength, purity, and efficacy of the leaves.