bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of different types of exercise intensity on improving physical health in children and adolescents: A systematic review
Authors: Zhou Xianxian , Li Jiayu , Jiang Xiaoping 
Published: January 2024

Abstract
A substantial body of empirical evidence reveals that physical activity is associated with a wide range of positive physical and mental health outcomes. However, a dearth of comprehensive syntheses is observed concerning the varying effects of different exercise intensities on the improvement of physical health among children and adolescents. This review aims to systematically study the effects of different exercise intensities on the physical fitness of children and adolescents, to determine the optimal exercise intensity for improving physical fitness and health, and to provide a relevant theoretical basis for optimal the physical education curriculum in schools.This study employed a systematic search strategy across four online databases (PubMed, Scopus, EBSCO, and Web of Science). Intervention studies that met the inclusion criteria underwent a thorough screening process, and their methodological quality was assessed utilizing the PEDro scale. The selected literature was systematically analyzed and evaluated through induction, summary, analysis, and evaluation. These findings indicate that high-intensity exercise training exerts significant positive effects on body composition, cardiopulmonary function, blood pressure, and muscle health in children and adolescents. Therefore, we suggest that schools should focus on high-intensity sports in their physical education curriculum, which can further improve the students' physical fitness and health.
Gluten-free corn cookies fortified with stinging nettle leaf flour: Effect on instrumental properties, storage stability, and health benefits.
Authors: Tanyitiku Mary Nkongho , Bessem Prisca , Petcheu Igor Casimir Njombissie 
Published: January 2024

Abstract
Background
The consumption of gluten-free corn cookies is becoming very popular among non-celiac and celiac individuals. However, the absence of gluten and other nutrients in corn generally leads to cookies of lower quality in terms of nutritional value, texture, colour, and shelf-life. To improve the quality characteristics of corn cookies and thus contribute to the increasing demand for gluten-free products, this study investigated the nutritional and physicochemical effect of incorporating an underutilised herb (stinging nettle leaves) into corn cookie preparations. The storage stability at room and frozen temperatures of the formulated nettle enriched corn cookies was also investigated and compared with 100% corn cookies.
Results
Nettle leaf flour increased (p < 0.05) the mineral and protein content of corn cookies from 0.32 to 2.56% and 6.44 to 21.52% as well as decreased the fat content from 2.13 to 1.81% respectively. Total phenolic content and antioxidant activity also increased in all formulated nettle enriched cookies while starch digestion significantly (p < 0.05) reduced from 48.60 to 30.18%. Furthermore, cookie hardness and colour, which are important determinants of consumers acceptance of corn cookies, significantly (p < 0.05) changed indicating a softer nettle enriched corn cookies. All nettle-enriched corn cookies were within acceptable shelf-life limits in terms of water activity, peroxide value, and microbial count within six months of storage.
Conclusion
The incorporation of nettle leaf flour improved the nutritional, physical and shelf-life properties of gluten-free corn cookies, as well as indicated the hypoglycemic potential of nettles as a food ingredient in bakery products.
Based on Logistic regression analysis, the prediction model of joint detection factors for postoperative incision infection in spinal surgery was established
Authors: Xie Bang-lin , Wang Zhi-yong , lin ling-zhen , Guo Run-sheng , Xu Tian-tian , Yang Xiao-wei , Yang Xin-ming , Ai Qiu-xiao , Zhang Meng-yi , Zhang Bin 
Published: January 2024

Abstract

OBJECTIVES
A retrospective study was conducted on patients who underwent spinal implant surgery in our hospital from June 2019 to June 2022. The predictive model of postoperative incision infection combined detection factor was constructed by Logistic regression analysis and other statistical methods, and receiver operating characteristic curve (ROC) was drawn to analyze the application value of the model.
METHODS
A total of 888 patients who underwent spinal surgery in our hospital from June 2019 to June 2022 were included. The patients' age, hypertension, diabetes and other disease history were retrospectively analyzed. Patients who underwent blood cell analysis and C-reactive protein serological detection 3 days after surgery were screened out, and relevant clinical data were collected. The independent risk factors of SSI were screened out by Lasso regression and Logistics regression analysis, and the prediction model of SSI joint detection factors was established according to the independent risk factors, and the application value of the model was analyzed by receiver operating characteristic curve (ROC) and calibration curve.
RESULTS
A total of 16 risk factors of 888 patients were analyzed by Lasoo regression model. Gender (regression coefficient: -0.241), age (regression coefficient: 0.0382), hypertension (regression coefficient: -0.826), diabetes (regression coefficient: 1.953), smoking history (regression coefficient: 0.692) 5 related predictors. Logistic regression analysis of Lasoo analysis results showed that age: (OR= 1.024,95%CI: 0.984-1.169), smoking history: (OR=1.512,95%CI :0.416-4.513), diabetes: (OR=5.898,95%CI: 2.075-16.240); CRP: (OR= 1.029,95%CI: 1.020-1.039) four independent risk factors. Combined factor prediction Normogram was established according to age, diabetes, smoking history and C-reactive protein value 3 days after operation. The C index of the Normograph model based on the above predictive factors was 0.9, and the AUC value was 0.900. The calibration curve shows that the predicted results are in good agreement with the observed results。
CONCLUSION
The combined prediction model based on age, diabetes, smoking history and C-reactive protein 3 days after surgery has potential clinical application value for surgical site infection after spinal surgery.
Familial and Cultural Dynamics: Nurturing Healthy Eating Habits and Combating Obesity Among Palestinian Children: A mixed method study
Authors: Jabali Oqab , Jabali Shaden 
Published: January 2024

Abstract
Background
Not enough research has been done to specifically examine how family monitoring affects how Palestinian children develop their eating habits, especially when it comes to preventing and treating obesity. Motivated by the Health Belief Model (HBM) and with an emphasis on familial and cultural dynamics, this study attempts to explore how families and communities shape healthy eating habits and fight obesity in Palestinian children.
Methods
To comprehensively characterize these processes, a mixed-methods approach is employed, combining quantitative analysis and structured interviews. The study used a purposive sampling technique to administer a survey, resulting in an initial sample of (185) friends. After data collection, (165) surveys were available for statistical analysis. In the qualitative approach, (18) individuals were chosen from the researchers' network, focusing on those actively involved in society and displaying high social networking site engagement.
Results
The quantitative findings indicate that while familial participation greatly influences children's eating choices, combining religious and cultural traditions prevents childhood obesity significantly. With the exception of variances in parental engagement depending on place of residence, which favor villages over towns, no substantial differences in parental involvement are detected across demographic categories. Qualitatively, a large portion of Palestinian couples believe their children are not vulnerable due to resilience and proactive health consciousness. They prioritize preventative measures like food choices, and consider economic constraints, cost, availability, and cultural influences in their nutritional decisions.
Conclusion
The study highlights the importance of culturally responsive public health initiatives and the cultural foundations of eating patterns. Notwithstanding certain drawbacks, such as the cross-sectional design and dependence on self-reported data, the results advance our knowledge of how families shape health-related behaviors. This study recommends the development of culturally relevant interventions for the Palestinian setting, looking into intersectionality, and expanding samples to address childhood obesity using other methodologies.
Adherence to mask wearing and social distancing following vaccination and use of lateral flow testing during the COVID-19 pandemic in England and Wales: Results from a cross-sectional study nested within the prospective Virus Watch household community cohort study
Authors: Antonopoulou Vivi , Ong Madeline , Meyer Carly , Beale Sarah , Lorencatto Fabiana , Michie Susan , Aldridge Robert W. , Hayward Andrew 
Published: January 2024

Abstract
Background
Personal protective behaviours (PPBs) played a crucial role in limiting the spread of infection during the COVID-19 pandemic, yet adherence to these behaviours varied at population level. Understanding the factors influencing adherence to protective behaviours is important, as PPBs will be a critical part of the response in future pandemics. Using behavioural science, we investigated the influences on adherence to PPBs, focusing on face mask wearing, social distancing, and lateral flow testing (LFT).
Methods
Two online surveys, the first gathering data on mask wearing and social distancing, and the second on lateral flow testing, were conducted in July and August 2021 with a sample from England and Wales (N = 20,488 (survey 1) and N = 26,613 (survey 2)). The survey questions were designed based on the Capability, Opportunity, Motivation (COM-B) model of Behavior. Multivariate models were used to examine associations between identified influences and adoption of these protective behaviours.
Results Most respondents reported wearing a face mask in public indoor places (88.5%) and maintaining a 1+ metre distance (86.8%) all or most of the time. After two doses of COVID-19 vaccine, social distancing decreased with 48.3% reporting meeting friends or family and 38.3% visiting indoor places more frequently. Motivation, Opportunity and Capability factors were significantly associated with increased odds of wearing a face covering and social distancing.
Among individuals who indicated using an LFT (comprising 68% of the total sample), 50.4% reported engaging in routine testing. For those who had never used an LFT, the predominant reason cited was a perceived lack of necessity for testing (55.3%). Statistically significant associations were found between routine testing and accurate interpretation of test results across all LFT belief-based statements (p < 0.05).
Conclusions
Findings indicated high levels of adherence to face masks, social distancing, and lateral flow testing, even amid reduced restrictions and high vaccination rates. Utilising a behavioural science framework, factors related to capability, opportunity, and motivation were found to significantly influence the use of these protective behaviours. Our recommendations can inform public health intervention design and guide the selection of implementation strategies for public health emergencies preparedness.
Changes in the Quality of Life in Patients Suffering from Knee Osteoarthritis Treated with Bone Marrow Aspirate Concentrate, Platelet-Rich Plasma, and Hyaluronic Acids- A Prospective, Randomised Study
Authors: Dulic Oliver , Abazovic Dzihan , Matijevic Sara , Rasovic Predrag , Janjic Natasa , Obradovic Mirko , Ninkovic Srdjan , Tosic Milan , Lalic Ivica , Baljak Branko , Matijevic Radmila , Milinkov Milan 
Published: January 2024

Abstract
Background: The aim of this investigation was to identify and compare changes in the quality of life among patients with knee osteoarthritis treated with injections of bone marrow aspirate concentrate, platelet-rich plasma, and hyaluronic acid.
Methods: The study employed a single-center prospective clinical trial with three study arms, and data were collected through repeated measurements using the self-reported SF-36 scale. To analyze the data's nature, linear mixed models (LMMs) were utilized to determine which of the three injection types was most effective in enhancing the quality of life. LMMs extend the principles of linear regression to accommodate correlated observations and analyze data collected at various time points.
Results: A total of 175 patients underwent treatment and screening over a 12-month period. Patients who received bone marrow aspirate concentrate (BMAC) exhibited greater score improvement compared to those receiving hyaluronic acid (HA) or platelet-rich plasma (PRP). This effect was most prominent in role limitations due to physical health and physical functioning. Additionally, results indicated score improvements for patients receiving PRP compared to those receiving HA, though not all findings achieved statistical significance.
Conclusions: Our study demonstrated that patients treated with BMAC experienced a more significant enhancement in quality of life compared to those receiving HA and PRP. The most substantial improvement was observed in factors related to physical movement, indicating the effectiveness of BMAC in restoring patients' physical functioning. Study limitations include recruitment from a single center and a relatively small dataset, particularly for those undergoing HA and PRP therapy
Clinical Trial Registration:retrospectively registered NCT03825133 ( ClinicalTrials.gov)
First detection and diversity of Astroviruses in wild migratory birds of Sakhalin Island, North Pacific
Authors: Zhirov Dmitry , Dubovitskiy Nikita , Derko Anastasiya , Loginova Arina , Sobolev Ivan , Ktitorov Pavel , Kulikova Olga , He Guimei , Wang Zhenghuan , Wang Wen , Alekseev Aleksander , Shestopalov Alexander , Sharshov Kirill 
Published: January 2024

Abstract

Avastrovirus (AAstV) is a genus of bird viruses infected are associated with avian diseases, including enteritis, growth retardation, nephritis and hepatitis leading to economic losses to farms and affecting food production worldwide. Despite numerous studies, data on diversity, phylogeny and epidemiology are presented mainly for poultry viruses. Studies on astroviruses of wild bird population highlight broad genetic diversity of viruses and limited understanding of their biological and ecological properties. In this study, we detected avastrovirus for the first time in wild migratory birds of the families Anatidae and Columbidae from Sakhalin Island, North Pacific Ocean. Phylogenetic analysis data showed the presence of Avastrovirus 2 and Avastrovirus 3 in wild doves and wild ducks, respectively. The data obtained shed light on the circulation of astroviruses on Sakhalin Island, which is crossed by East Asian–Australasian Flyway.
Prophylactic Third Molar Removal: Are Oral Surgeons and Orthodontists Aligned in Preventive Approaches?
Authors: Guldiken Ipek Necla , Gulsever Serap , Malkoc Yagmur , Yilmaz Zeynep Cukurova , Ozcan Mutlu 
Published: January 2024

Abstract

Background: A consensus favors extracting impacted third molars in the presence of clinical symptoms, but no consensus exists on their management when asymptomatic. Healthcare professionals from different fields of expertise may approach the extraction of these teeth differently.
Methods: This study aimed to compare the perspectives of oral surgeons and orthodontists regarding the indications for asymptomatic third molar removal. This cross-sectional study collected information by asking participants why they prefer extracting asymptomatic third molars. Descriptive statistics were used to evaluate the obtained data. The significance level was p<0.05.
Results: Prophylactic extraction of partially impacted molars was more favored among the participants (p<0.01). The orthodontists preferred prophylactic extraction due to the risk of late anterior dental crowding (LADC); however, the surgeons preferred pre-pregnancy extractions (p<0.05). The extraction decision for partial impaction was higher in females when the risk of distal caries was considered. For fully impacted ones, it was higher in males when the risk of caries and pericoronitis were considered (p<0.05).
Conclusions: Orthodontists preferred extraction because of the risk of LADC and caries, while surgeons focused on preventing pericoronitis, pathology, focal infection, and symptoms during pregnancy. This divergence between the participants may inform the guidelines for prophylactic management of third molars. These findings may be pertinent in gender medicine.
Clinical relevance: This study has been enlightening for departments to consult each other before the extraction of a patient's asymptomatic third molar.
Translator IL2RA contributes to poor prognosis in kidney clear cell carcinoma by affecting the early stage of lymphocyte activation
Authors: Chen Xiaochi , jiang kui , liu Weiqi , Qu Meijun , Jin Minli , Li Yutong , Zhang Tianqi , Liang Yixin , Lu Ye , Wang Huada 
Published: January 2024

Abstract
Background
IL2RA has been shown to play an important function in tumorigenesis. However, the exact mechanism by which it functions in KIRC is poorly understood.
Methods
Initially, we performed a pan-cancer study using the TIMER database to identify the expression variation of IL2RA in KIRC. Then, Kaplan-Meier, clinicopathological, and COX regression analyses using the TCGA database were performed to show the association of the IL2RA expression level with overall survival and clinicopathology of KIRC patients. Next, we used GO and KEGG enrichment analysis to reveal the association of IL2RA level with immunity. Finally, in order to explore the association of IL2RA expression levels with immunity, our group adopted an immunotherapeutic research approach to determine the mechanism of its influence.
Results
IL2RA was found to have high expression levels in KIRC and to be correlated with clinicopathology. Based on GSEA analysis, it was discovered that IL2RA is associated with immune pathways in KIRC. Immunotherapy analysis provided further clarification on the correlation between IL2RA and immunotherapy.
Conclusions
The expression level of IL2RA has an important role in the development and escape of KIRC. IL2RA has a complex immunoregulatory mechanism in this tumor. Our study suggests that it contributes to the poor prognosis for KIRC patients mainly by affecting the early stages of lymphocyte response.
Comparative analysis of Attention-based CNN andViT for processing ECG image data in joint fusion
Authors: Thakur Arjun , Agasthi Pradyumna , Chao Chieh-Ju , Farina Juan Maria , Holmes David R. , Fortuin David , Ayoub Chadi , Arsanjani Reza , Banerjee Imon 
Published: January 2024

Abstract

Percutaneous Coronary Intervention (PCI) is a widely utilized standard ofcare and efficacious intervention in the management of coronary artery disease,improving prognosis and symptoms for many patients. Prediction of post-PCIoutcomes contributes to effective patient management and quality improvementinitiatives in healthcare. Our study focuses on comparative performance analysisfor state-of-the-art vision transformer (ViT) and convolutional neural network(CNN) on multimodal data analysis in a joint fusion framework. We integrateimages of electrocardiogram (ECG) data and tabular electronic health records(EHR) to predict 3 clinically relevant post-PCI (6 months) endpoints - heart failure hospitalization, all-cause mortality, and ischemic stroke. To design a comparativemodel for ViT, we proposed a new joint fusion architecture that consistsof a convolutional neural network (CNN) with a convolutional block attentionmodule (CBAM). The learned representations are combined at an intermediatelayer followed by processing these representations using a fully connectedlayer. The proposed model demonstrates excellent performance with the highestAUROC scores of 0.849, 0.913, and 0.794 for predicting heart failure hospitalization,all-cause mortality, and stroke, respectively. Surpassing the baseline EHRmodel and ViT, the proposed CNN+CBAM fusion model showcases superiorpredictive capabilities for heart failure prediction.
The quality of bone and paraspinal muscle in the fragility osteoporotic vertebral compression fracture: a comprehensive comparison between different indicators
Authors: Zhan Sizheng , Ma Haoning , Duan Xingguang , Yi Pi 
Published: January 2024

Abstract

Purpose: To evaluate the value of five indicators in predicting OVCF through a retrospective case-control study, and explore the internal correlation of different indicators.
Method: We retrospectively enrolled patients over 50 years of age who had been subjected to surgery for fragility OVCF at China Japan Friendship Hospital from January 2021 to September 2023. Demographic characteristics, T-score based on dual-energy X-ray absorptiometry (DXA), CT-based Hounsfield unit (HU) value, vertebral bone quality (VBQ) score based on magnetic resonance imaging (MRI), relative cross-sectional area (rCSA) and the rate of fat infiltration (FI) of paraspinal muscle were collected. A 1:1 age- and sex-matched, fracture-free control group was established from patients admitted to our hospital for lumbar spinal stenosis or lumbar disk herniation.
Results: A total of 78 patients with lumbar fragility OVCF were included. All the five indicators were significantly correlated with the occurrence of OVCFs. Logistic regression analysis showed that average HU value and VBQ score were significantly correlated with OVCF. The area under the curve (AUC) of VBQ score was the largest (0.89). There was a significantly positive correlation between average T-score, average HU value and average total rCSA. VBQ score was significantly positive correlated with FI.
Conclusion: VBQ score and HU value has good value in predicting of fragility OVCF. In addition to bone mineral density, we should pay more attention to bone quality, including the fatty signal intensity in bone and the FI in paraspinal muscle.