bluuebunny/crossref_metadata_2025_split huggingface dataset:
Posaconazole followed by combination itraconazole and terbinafine for treatment of disseminated histoplasmosis in a cat
Authors: Farber-Klein Maia V. , McQuinn Erin R. 
Published: February 2024

Abstract

OBJECTIVE
This is the first reported use of posaconazole for the treatment of feline disseminated histoplasmosis.

ANIMALS
Approximately 1-year-old female spayed domestic longhair cat.

CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES
The cat presented to our institution with weight loss, lymphadenomegaly, hepatosplenomegaly, limb edema, abdominal fluid distension and ulcerated cutaneous nodules. The cat had been previously diagnosed with disseminated histoplasmosis at another institution approximately 6 months prior. Clinical signs had been refractory to treatment with fluconazole. Itraconazole had next been tried, and the cat’s weight continued to decline, lesions failed to regress, and the cat formed abdominal fluid distension and marked pelvic limb edema.

TREATMENT AND OUTCOME
The cat was prescribed posaconazole along with prednisolone. The cat’s demeanor, body weight, and lesions all markedly improved. Histoplasma antigen was undetectable in urine samples while the cat was receiving posaconazole. However, posaconazole blood levels paired with markedly elevated ALT suggested potential toxicity and the drug was discontinued. Upon cessation of posaconazole, the cat’s lesions returned with cytologic evidence of intralesional Histoplasma yeast. Itraconazole combine with terbinafine was prescribed. At last follow-up, the cat was clinically well, off all anti-fungal medication, and without detectable Histoplasma antigen in the urine.

CLINICAL RELEVANCE
Posaconazole therapy showed promise in this case. Had a safe and therapeutic dose been arrived at, we suspect that posaconazole would have cleared or maintained clinical remission of this cat’s disease. This is the first report using posaconazole and the first successful report using combination itraconazole and terbinafine for the treatment of feline disseminated histoplasmosis. Generic drugs were used throughout this case report; the drug manufacturers are unknown to the authors.
Implementation of the Energy Justice Concept in Strategies and Projects of Foreign Energy Companies
Authors: Krasnoperova A. B. 
Published: February 2024

Introduction. The given article examines the challenges of ensuring energy justice in business models of energy companies. It identifies ways in which organizations and businesses providing energy services locally, regionally and internationally can successfully integrate social justice values into business strategies, ensuring that their operations are aligned with the principles of equitable provision of energy services.Materials and methods. Materials used for the given research include foreign and Russian studies on energy justice issues, statistical data and news sources from the world media. The methodological basis consists of such scientific methods as qualitative and quantitative analysis, synthesis, comparative research and statistical analysis.Results of the study. Analysis of the activities of foreign energy companies suggests that energy justice is a highly effective “tool” not only from the point of view of conceptualizing the theoretical idea of an energy just world and effectively analyzing a wide range of energy-related issues, but can also be considered as a valuable contribution to the actual process of developing energy policy and a framework for assessing the sustainability of energy-related projects and initiatives. The concept of a public interest company based on the principles of energy and social justice can be defined as a set of guidelines aimed at transforming existing business practices to ensure that these practices are consistent with the principles of energy justice.Discussion and conclusions. The given re­search revealed that the degree of adherence to energy justice principles determines whether certain business practices or specific projects are consistent with its paradigm. At the same time, as evidenced by available scientific research on this issue, commercial activity and the creation of social and environmental values are not internally contradictory concepts. On the contrary, energy justice guidelines and aspects can be successfully integrated into various business models at local, subnational, regional and global levels.
Memorial Law: National and International Aspects
Authors: Vasiliev A. A. , Uzhanov A. E. , Pechatnova Yu. V. 
Published: February 2024

Introduction. This article conducts an interdisciplinary study of memory policy, which includes terminological explication and legal analysis of concepts similar in meaning, assessment of the relevance and need to legalize terms related to memory policy, determination of the effectiveness of official memory policy, prediction of its political and social consequences in the long term and exploring the normative limits of national memorial legislation. The purpose of the study is the conceptualization of memorial law.Materials and methods. The main research method is participant observation of the processes of implementation in Russian society and abroad of the concepts of national, historical and social memory, as well as the construction of norms and regulations for establishing legal relations in the field of conservation of military memorial heritage objects. Methods of express diagnostics of problem situations, legal assessment of incidents, sociological and expert surveys (including questionnaires and testing), and modeling were used.Research results. As a result of the study, the need to develop a special federal law on the protection of the military memorial heritage of the Russian Federation, as well as the development of an international (universal) Charter (Convention) on the protection of military memorial heritage sites formed as a result of the Second World War, was substantiated. Discussion and conclusion. It has been established that there is no single position in the scientific community regarding the need for memorial legislation. This largely depends on the political and ideological preferences of a particular author. At the same time, it was concluded that in legal science the conceptual foundations for the formation of memorial law as a special legal complex for the preservation, transmission and protection of historical memory and memorial (war memorial) heritage have been poorly studied. In addition, both at the level of legal doctrine and according to law enforcement practice, the issue of the status and legal means of preserving military memorial heritage has been practically not studied. In this connection, the authors propose the development of a Union Nation Charter for the Protection of Military Memorial Heritage for the purpose of holistic and comprehensive legal regulation of the area under study.
International Cooperation of BRICS Countries in the Field of Forced Migration: Topical Issues and Prospectives
Authors: Pchelintseva V. V. 
Published: February 2024

Introduction. International law acts of BRICS countries enshrine their attachment to enforcement of the international cooperation in the field of population, in particular migration. The rise in the number of forced migrants on their territories as well the accession of new States to BRICS explains the topicality of the research into the particularities and prospects of BRICS countries’ cooperation in the sphere of forced migration. Meanwhile the international law acts adopted by BRICS countries do not enshrine their unified position as regards general principles of their cooperation in the sphere of forced migration.Materials and Methods. The conciliation theory according to which creation of international law norms results from the reconciliation of international legal position of its subjects serves as the theoretical framework for the present research. While exercising autonomous international legal policy, each State aims at enshrining the principles of its foreign policy in the international law acts. International legal positions of States are enshrined in their treaties, national legislation and unilateral acts. The article contains the results of a comprehensive comparative analysis of international legal positions of BRICS countries as regards international law norms governing the legal status of forced migrants. The subject of the research includes universal treaties, BRICS countries’ international law acts, national legislation and unilateral acts.Results. BRICS is an intergovernmental institution, which is not de jure an international organisation. The acts adopted by BRICS countries are joint unilateral acts enshrining their unified positions on international law. International cooperation of BRICS countries in the sphere of forced migration is based on principles of rule of international law and multilateralism as well as their coincident and similar positions on interpretation and application of international law norms governing the legal status of forced migrants. BRICS international law acts enshrine the international law concepts applicable to the international cooperation in the field of forced migration.Discussion and Conclusions. Conciliation of international law positions of BRICS countries as regards interpretation and application of international law concepts of “durable solution to the problem of forced migrants”, “responsibility sharing”, “solidarity”, “common but differentiated responsibility” as well as other international law concepts upon which the international cooperation in the field of forced migration is based should be considered a prospective area of their international cooperation.
Akuntabilitas Pengelolaan Alokasi Dana Desa
Authors: Mais Rimi Gusliana , Nuryati Tutty , Handoko Sakti Sri , Lestari Lestari 
Published: February 2024

Objectives: This study aims to evaluate the village government's role in effectively managing Village Fund Allocations in Gadung Village, particularly during the planning, implementation, administration, reporting, and accountability stages in adherence to the Minister of Home Affairs Regulation Number 20 of 2018.Design/Method/Approach: Employing qualitative methods such as interviews, observation, and documentation, this research elucidates how the village government handles the allocation of village funds in Gadung Village. The study was conducted at the Gadung Village office.Results/Findings: The findings indicate that the village government demonstrates accountability across all stages of planning, implementation, administration, reporting, and accountability in managing the Village Fund Allocation (VFA) in Gadung Village. The planning stage utilizes Musrenbangdes as a mechanism to ensure accountability. The implementation stage adheres to regulatory mechanisms, while the administration stage showcases accountable management through meticulous bookkeeping and reports. The reporting and accountability stages follow a guided report format to ensure transparency.Theoretical contribution: This study contributes to the enhancement of knowledge and awareness regarding the crucial role of accountability in reporting the use of VFA.Practical contribution: The utilization of VFA report of the Bangka Village requires continuous monitoring at each implementation stage, particularly in administration, to ensure compliance with regulations and prevent legal discrepancies, thereby fostering increased trust in ADD in the future.Limitations: This study specifically explores village financial management as outlined in the Minister of Home Affairs Regulation Number 20 of 2018, encompassing planning, implementation, administration, reporting, and accountability. However, a comprehensive review of each component of VFA financial management and a detailed analysis of nominal village finances have not been undertaken
PREPARO DO SOLO EM FAIXAS NA CULTURA DA CANA-DE-AÇÚCAR: ATRIBUTOS FÍSICOS E DESEMPENHO OPERACIONAL
Authors: Dos Reis Gustavo Naves , Cortez Jorge Wilson 
Published: February 2024

Objetivo: Objetivou-se avaliar o preparo do solo em faixas na cultura da cana-de-açúcar sob os atributos físicos do solo, biometria da cultura e o desempenho dos conjuntos mecanizados em Neossolo Quartzarênico Órtico típico.

Referencial teórico: O preparo de solo consiste na etapa mais importante da instalação do canavial. Esse processo visa proporcionar condições físicas adequadas ao solo, com benefícios ao desenvolvimento e longevidade da cultura.

Método: Foram feitos dois tratamentos (T1 e T2), em que T1 utilizou-se o canteirizador customizado com hastes subsoladoras e enxada rotativa e em T2, grade de discos + subsolador convencional provido de rolo destorroador. O delineamento foi em blocos casualizados e os dados submetidos à análise de variância aplicando-se o teste de Tukey a 5% de probabilidade. A estabilidade do processo com relação à biometria, foi complementada pelo Controle Estatístico de Processo (CEP) por meio das cartas de controle a partir dos limites inferior (LIC) e superior (LSC).

Resultados e conclusão: O T1 melhora a estrutura e o perfil do solo até 0,285 m, quando comparado ao T2. O desempenho operacional foi melhor nos conjuntos mecanizados do T2. A qualidade física do solo no T1 proporciona melhor desenvolvimento da cana-de- açúcar.

Implicações da pesquisa: a pesquisa demonstrou a importância da adequação de maquinário agrícola para aumentar a qualidade física do solo.

Originalidade/valor: com este estudo é possível difundir para a comunidade científica e produtora métodos de melhoria da qualidade física do solo.
Sustainability Index as A Proposal for Socio-Environmental Evaluation of The Performance of The State Court of Justice of Alagoas-Brazil
Authors: Silva Cleriston Santos , Faccioli Gregorio Guirado , Gomes Filho Raimundo Rodrigues , Dos Santos Alane Regina Rodrigues , Pinto Junior Ézio dos Santos , Machado Thiago Perez 
Published: February 2024

Purpose: Analyze sustainability in the socio-environmental management of the judiciary, from the perspective of indicators defined by the National Council of Justice (CNJ) and propose a sustainability index for the socio-environmental management of the PJ.

Theoretical framework: Indicators are present in everyone's lives, they are everywhere. They are considered a management tool. Models for assessing sustainability through specific indicators and indices have been the subject of study in several studies, from the perspective of different dimensions.

Method: Application of the methodology proposed by Calório (1997), combined with Daniel et al (2001), Sobral, Almeida and Gomes (2012), Faccioli and Gomes (2021) and adaptations, with 21 indicators in the environmental, economic and social dimensions in 9 categories defined by the CNJ aligned with the Sustainable Development Goals (SDG). The Sustainability Index, its classification and scenario analysis are obtained.

Results and discussion: An index and model aimed at evaluating the socio-environmental sustainability of the judiciary is presented, in which the general sustainability index - IS0-100 was 20.24%, a level considered bad and classified as a pessimistic scenario, pointing out a warning for the economic and environmental dimensions, in the categories: paper, disposable cups, electricity and mineral water, due to expenses/consumption. The indicators consumption of returnable packaging for mineral water (IA9) and expenditure on mineral water in returnable packaging (IE8) presented the highest level of unsustainability (0.0%).

Implications of the research: This research demonstrated that the methodology can be applied to the Judiciary sphere, in the Courts of Justice, and that it has implications in the form of monitoring, and can be used as a parameter for evaluating sustainability in socio-environmental management and contribute to decision-making.

Originality/value: The literature is silent in relation to socio-environmental management in the judiciary with the SDGs, there is a lack of studies to assess sustainability. Thus, the knowledge developed in this research fills a gap by proposing a Sustainability Index for this sphere of power.
Nonequilibrium Heating/Cooling Effects in a Mach Number 10 Hydrogen-Fueled Scramjet
Authors: Liu Hang , Yao Wei , Zhang Xu , Zhang Xiaoyuan , Liu Jianwen , Yue Lianjie , Sun Quanhua 
Published: February 2024

The influence of thermal/chemical nonequilibrium on a hydrogen-fueled [Formula: see text] 10 scramjet was analyzed by combining the JF-2 4 s hock tunnel test and improved delayed detached eddy simulation modeling. A remarkable change in flame stabilization mode when incorporating the two-temperature nonequilibrium model was observed. The nonequilibrium heating and cooling effects were analyzed for different sections of the scramjet. The nonequilibrium heating effect facilitates the upstream flame propagation by inducing an early ignition and thickening the inlet boundary layer. The nonequilibrium heating or cooling effect is generally weak in the nearly constant-area isolator and combustor, where the flow is mainly influenced by the chemical nonequilibrium with a variation of 10% in reaction rate. The nonequilibrium cooling effect mainly exists in the expanding nozzle, where [Formula: see text], but the energy replenishment from vibrational mode to trans-rotational mode is nearly frozen when [Formula: see text]. Under both conditions, the final mixing is nearly complete, and net thrust has been achieved. When considering the nonequilibrium effects, the final combustion efficiency increases from 87.68 to 99%, together with a 53.94% rise in peak pressure ratio and a 137.04% rise in specific impulse.
Burns in epileptic patients: Pattern and outcome.
Authors: Riaz Ahmed Khan Afridi  , Sadaf Obaid  , Hamza Khan Shahbazi  , Zahra Tauqeer  
Published: February 2024

Objective: To determine the pattern and outcome of burns in epileptic patients. Study Design: Retrospective study. Setting: Plastic and Burn Unit, Lady Reading Hospital, Peshawar. Period: January 2021 to Decmber 2022. Material & Methods: The research was conducted at the Plastic surgery and burn unit of Lady Reading Hospital Peshawar. Digital records of 35 epileptic patients admitted in the last five years were extracted. The demographics, burn pattern, total body surface area, level of burn, surgical outcome, complications, and length of hospital stay of epileptic patients were extracted from the electronic record. IBM-SPSS version 20 was used to analyze the data. Results: Over the last five years, 35 epileptic patients have been admitted to our unit. Males made up 28.6% of our patients, while females were 71.4%. The patient's average age was 24.14 years ±16. 28 SD. The most common pattern in our patients was fire burn (62.9%), followed by scald (25.7%), and the least common pattern was 11.4%. 10 to 20% of body surface area burns were seen in 51.4% of patients, less than 10% in 20% of patients, and >20% burns in 28.6% of patients. The majority of the patients (37.1%) had a full-thickness burn, followed by mixed burns (31.4%), deep partial-thickness burns (20%), and superficial partial-thickness burns (11.4%). Twenty-eight patients stayed in the hospital for 1 to 14 days, 04 patients for 15 to 30 days, and 03 patients for 31 to 45 days. Conclusion: Epilepsy-related burns are a serious public health concern in developing nations, putting a significant burden on burn units due to the severity of the burns and the duration of hospital admissions.
Cardiac wet lab by residents with limited resources in newly established cardiac center: Need of the hour.
Authors: Nasir Abdul , Aamir Iqbal  
Published: February 2024

HIGHLIGHTS

It is possible to establish a wet lab for cardiac surgery training in resource-constrained settings in developing countries.

Residents can arrange wet lab sessions using their own limited resources.

This enhances their surgical skills and boosts their confidence in the operating room.

Faculty can provide supervision and feedback without any concern about harming patients.
Analisa Kekuatan Impact Serta Kekuatan Tarik Komposit Fiberglass Pembuatan Perahu Nelayan
Authors: Abdul karim Ivan junaidy 
Published: February 2024

Indonesia memiliki garis pantai yang panjang sehingga sebahagian besar masyarakat pesisir memilih nelayan sebagai mata pencaharian. Masyarakat pesisir kebanyakan berprofesi sebagai nelayan. Alat tangkap nelayan tradisional kebanyakan terbuat dari kayu atau batang pohon yang digali. Kapal kayu ataupun logam sangat mahal biaya produksinya dibanding dengan faiberglass yang memiliki kelebihan teknis dan ekonomis. Ketebalan lapisan fiber perlu diperhatikan shingga kapal dapat diproduksi dengan efisien. Penelitian ini menggunakan tiga jenis fiberglass yakni dengan fariasi serat matt 350, matt 450, woven 600, dengan variasi layer 4, 8, 12 dengan resin berjenis yukalak 157. Komposit dibuat menggunakan metode hand lay up dengan ukuran spesimen uji impak dibuat menggunakan standarisasi ASTM D256 dan spesimen uji tarik menggunakan standarisasi ASTM D 638 tipe IV. Hasil pengujian impak menunjukan bahwa serat 4 lapis memiliki kekuatan impak sebesar 8.417 , pada serat 8 lapis sebesar 9.88 dan pada serat 12 lapis sebesar 224.1 Kekuatan tarik serat 4 lapis memiliki kekuatan tarik rata-rata sebesar 184,85 MPa serat 8 lapis sebesar 211,62 MPa dan pada serat 12 lapis sebesar 231,70 MPa.
Pengembangan Soal Literasi Numerasi Konteks Budaya Bangka Bagi Siswa SD
Authors: Rachma Kurniasi Eka , Hevitria Hevitria , Fauziani Meilidya , Safitri Indri 
Published: February 2024

Literasi dan numerasi merupakan kemampuan penting abad 21. Soal pada jenjang SD mengenai numerasi masih perlu dikembangkan. Pengembangan ini menyangkut konten numerasi dan konteks budaya daerah yang perlu dimasukkan pada soal. Penelitian ini bertujuan untuk mengembangkan soal literasi numerasi konteks budaya Bangka Belitung untuk siswa SD. Metode penelitian yang dipilih adalah penelirian pengembangan dengan model pengembangan ADDIE. Prosedur yang dilakukan tahap Analisis yaitu menganalisis SK dan KD kelas empat SD pada mata pelajaran matematika, menganalisis kebutuhan siswa, analisis kebutuhan soal literasi numerasi dalam kurikulum 2013 dan kurikulum merdeka. Tahap desain peneliti membuat prototipe soal literasi numerasi konteks budaya Bangka Belitung. Tahap Development dilakukan validasi ahli materi dan ahli evaluasi mengenai soal yang sudah dikembangkan. Tahap Implementation dilakukan uji skala kecil dan skala besar pada subjek siswa kelas 4 SD. Tahap evaluasi dilakukan evaluasi formatif pada setiap tahapan pengembangan. Hasil penelitian yaitu 5 soal literasi numerasi konteks budaya Bangka Belitung dengan validasi ahli media sebesar 87% menyatakan valid, validasi ahli evaluasi menyatakan 92% valid. Pada skala kecil respon siswa 79% menyatakan layak dan pada skala besar 82% menyatakan layak. Uji kualitas butir soal yaitu validitas konstruk dinyatakan semua butir soal valid. Sedangkan reliabilitas dinyatakan soal reliabel. Penelitian ini memberikan hasil bahwa siswa mengalami kesulitan dalam memahami literasinya. Namun pada konten numerasi siswa merasa tidak sulit mengerjakannya. Pada saat membaca soal siswa merasa bangga bahwa beberapa tempat atau makanan yang mereka kenal dan temui sehari-hari bisa dipelajari dalam matematika.