bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avant-Garde and Kitsch in María Blanchard’s Neo-Cubism
Authors: De Ros Xon 
Published: October 2023

Abstract
The exceptionality of the women artists who achieved recognition within the circles of the avant-garde in the first decades of the twentieth century involved a number of performative strategies to avoid the risk of being confined to the category of ‘women painters’. The case of María Blanchard, a Spanish painter integrated in the School of Paris, exemplifies the problematics faced by women working in the avant-garde. Her trajectory from synthetic Cubism to neo-Cubist figuration follows the pattern of many of her male contemporaries working under the sociopolitical and market pressures in the post-war period, but the simultaneous assimilation of and ironic distance from the prevailing aesthetic ideologies is a distinctive feature of her style shared by other women artists. As Cubism became mainstream and began to lose its subversive power, Blanchard’s interest in challenging conventional artistic discourses and hierarchies found expression in kitsch aesthetics.
Optimal Use of Radar Radial Winds in the HARMONIE Numerical Weather Prediction System
Authors: Ridal Martin , Sanchez-Arriola Jana , Dahlbom Mats 
Published: October 2023

Abstract
The use of radial velocity information from the European weather radar network is a challenging task, because of a heterogeneous radar network and the different ways of providing the Doppler velocity information. Preprocessing is therefore needed to harmonize the data. Radar observations consist of a very high resolution dataset, which means that it is both demanding to process as well as that the inherent resolution is much higher than the model resolution. One way of reducing the number of data is to create “super observations” (SO) by averaging observations in a predefined area. This paper describes the preprocessing necessary to use radar radial velocities in the data assimilation where the SO construction is included. Our main focus is to optimize the use of radial velocities in the HARMONIE–AROME numerical weather model. Several experiments were run to find the best settings for first-guess check limits as well as a tuning of the observation error value. The optimal size of the SO and the corresponding thinning distance for radar radial velocities was also studied. It was found that the radial velocity information and the reflectivity from weather radars can be treated differently when it comes to the size of the SO and the thinning. A positive impact was found when adding the velocities together with the reflectivity using the same SO size and thinning distance, but the best results were found when the SO and thinning distance for the radial velocities are smaller than the corresponding values for reflectivity.
Criticality dimension-based probabilistic framework to detect near crashes in a roundabout
Authors: Trullos Juan , Zhang Meng , Junghans Marek , Gimm Kay 
Published: October 2023

Abstract
Background
Preventing fatal traffic accidents towards Vision Zero is a challenge for the society. The collection of critical events from video recorded traffic data is of essential value for a better understanding on how and under what circumstances critical situations evolve. Identified behavioral patterns and derived infrastructural measures cannot only help to make driving safer, but also help to mature automated driving functions (ADFs) to make automated vehicles drive and interact more like humans especially in challenging situations. One flaw when developing ADFs is the dependency on synthetic simulated traffic scenarios.

Method
In this paper, a novel probability-based framework is proposed allowing to measure the degree of criticality C(d) based on two dimensions explaining risk: severity (delta-v) and proximity (distance).

Results
This metric is applied on real data of a roundabout. An initial evaluation of it was conducted using both a novel proposed method that takes the reaction of the second vehicle merged into account, and a practical application that shows a potential correlation between the traffic expert's perceived risk and the metric.

Conclusion
Quantifying risk on each of the collected real traffic scenarios makes testing ADFs possible in further more reliable and significant scenarios like near-crashes.
Summary-data based Mendelian randomization identifies gene expression regulatory polymorphisms associated with bovine paratuberculosis by modulation of the nuclear factor Kappa β (NF-κß)-mediated inflammatory response
Authors: Badia-Bringué Gerard , Canive Maria , Fernandez-Jimenez Nora , Lavín José Luis , Casais Rosa , Blanco-Vázquez Cristina , Vázquez Patricia , Fernández Almudena , Bilbao Jose Ramón , Garrido Joseba M. , Juste Ramón A. , González-Recio Oscar , Alonso-Hearn Marta 
Published: October 2023

AbstractGenome-wide association studies (GWAS) have identified host genetic variants associated with paratuberculosis (PTB) susceptibility. Most of the GWAS-identified SNPs are in non-coding regions. Connecting these non-coding variants and downstream affected genes is a challenge and, up to date, only a few functional mutations or expression quantitative loci (cis-eQTLs) associated with PTB susceptibility have been identified. In the current study, the associations between imputed whole-genome sequence genotypes and whole RNA-Sequencing data from peripheral blood (PB) and ileocecal valve (ICV) samples of Spanish Holstein cows (N = 16) were analyzed with TensorQTL. This approach allowed the identification of 88 and 37 cis-eQTLs regulating the expression levels of 90 and 37 genes in PB and ICV samples, respectively (False discorey rate, FDR ≤ 0.05). Next, we applied summary-based data Mendelian randomization (SMR) to integrate the cis-eQTL dataset with GWAS data obtained from a cohort of 813 culled cattle that were classified according to the presence or absence of PTB-associated histopathological lesions in gut tissues. After multiple testing corrections (FDR ≤ 0.05), we identified two novel cis-eQTLs affecting the expression of the early growth response factor 4 (EGR4) and the bovine neuroblastoma breakpoint family member 6-like protein isoform 2 (MGC134040) that showed pleiotropic associations with the presence of multifocal and diffuse lesions in gut tissues; P = 0.002 and P = 0.017, respectively. While EGR4 acts as a brake on T-cell proliferation and cytokine production through interaction with the nuclear factor Kappa β (NF-κß), MGC134040 is a target gene of NF-κß. Our findings provide a better understanding of the genetic factors influencing PTB outcomes, confirm that the multifocal lesions are localized/confined lesions that have different underlying host genetics than the diffuse lesions, and highlight regulatory SNPs and regulated-gene targets to design future functional studies.
Comparative genomics analysis provides insights into evolution and stress responses of Lhcb genes in Rosaceae fruit crops
Authors: Li Xiaolong , Jiang Zeyu , Zhang Chaofan , Cai Kefan , Wang Hui , Pan Weiyi , Sun Xuepeng , Gao Yongbin , Xu Kai 
Published: October 2023

Abstract
Background
Light-harvesting chlorophyll a/b binding proteins (Lhcb) play crucial roles in plant growth, development, and the response to abiotic stress in higher plants. Previous studies have reported that Lhcb genes were involved in the phytochrome regulation and responded to different light and temperature conditions in Poaceae (such as maize). However, the evolution and functions of Lhcb genes remains poorly characterized in important Rosaceae species.

Results
In this investigation, we conducted a genome-wide analysis and identified a total of 212 Lhcb genes across nine Rosaceae species. Specifically, we found 23 Lhcb genes in Fragaria vesca, 20 in Prunus armeniaca, 33 in Malus domestica ‘Gala’, 21 in Prunus persica, 33 in Rosa chinensis, 29 in Pyrus bretschneideri, 18 in Rubus occidentalis, 20 in Prunus mume, and 15 in Prunus salicina. Phylogenetic analysis revealed that the Lhcb gene family could be classified into seven major subfamilies, with members of each subfamily sharing similar conserved motifs. And, the functions of each subfamily was predicted based on the previous reports from other species. The Lhcb proteins were highly conserved within their respective subfamilies, suggesting similar functions. Interestingly, we observed similar peaks in Ks values (0.1–0.2) for Lhcb genes in apple and pear, indicating a recent whole genome duplication event (about 30 to 45 million years ago). Additionally, a few Lhcb genes underwent tandem duplication and were located across all chromosomes of nine species of Rosaceae. Furthermore, the analysis of the cis-acting elements in the 2000 bp promoter region upstream of the pear Lhcb gene revealed four main categories: light response correlation, stress response correlation, hormone response correlation, and plant growth. Quantitative expression analysis demonstrated that Lhcb genes exhibited tissue-specific expression patterns and responded differently to low-temperature stress in Rosaceae species.

Conclusions
These findings shed light on the evolution and phylogeny of Lhcb genes in Rosaceae and highlight the critical role of Lhcb in pear’s response to low temperatures. The results obtained provide valuable insights for further investigations into the functions of Lhcb genes in Rosaceae, and these functional genes will be used for further fruit tree breeding and improvement to cope with the current climate changes.
RFC2 promotes aerobic glycolysis and progression of colorectal cancer
Authors: Lou Fuchen , Zhang Mingbao 
Published: October 2023

Abstract
Background
Replication factor C subunit 2 (RFC2) participates in the growth and metastasis of various malignancies. Our study investigated the roles of RFC2 in colorectal cancer (CRC).

Results
RFC2 expression was upregulated in CRC tissues and cells. High RFC2 expression was associated with poor prognosis. Knockdown RFC2 inhibited proliferation, induced apoptosis, and suppressed migration and invasion of CRC cells. CREB5 was a transcription factor of RFC2, and CREB5 knockdown suppressed RFC2 expression. Furthermore, RFC2 promoted aerobic glycolysis and MET/PI3K/AKT/mTOR pathway.

Conclusion
RFC2 promoted the progression of CRC cells via activating aerobic glycolysis and the MET/PI3K/AKT/mTOR pathway.
Does disaster-related relocation impact mental health via changes in group participation among older adults? Causal mediation analysis of a pre-post disaster study of the 2016 Kumamoto earthquake
Authors: Matsuoka Yoko , Haseda Maho , Kanamori Mariko , Sato Koryu , Amemiya Airi , Ojima Toshiyuki , Takagi Daisuke , Hanazato Masamichi , Kondo Naoki 
Published: October 2023

Abstract
Background
Disaster-related relocation is associated with depression and post-traumatic stress disorder, especially in older adults. Disaster-related relocation often deprives survivors of opportunities for social group participation, potentially deteriorating their mental health. On the contrary, the relocation could also be an opportunity for optimizing social relationships, ending/reducing unwanted participation. This study examined the potential mediation effects of changing participation for the link of disaster-related relocation to mental health.

Methods
We analyzed a pre-post disaster dataset of functionally independent older adults from the Japan Gerontological Evaluation Study. Following the 2013 survey, a follow-up survey was conducted seven months after the 2016 Kumamoto earthquake (n = 828).

Results
The causal mediation analyses indicated that compared to no relocation, the relative risk for experiencing major depressive episodes among those relocating to temporary housing was 3.79 [95% confidence interval: 1.70–6.64] (natural direct effect). By contrast, the relative risk for those renewing (either ceased or started) group participation was 0.60 [95% CI: 0.34–0.94] (natural indirect effect).

Conclusions
Optimization of social ties according to a renewal of group participation status might have protected older adults in temporary housing against depression.
Evaluation of the effectiveness of the human-baited double net traps and BG traps compared with the human landing catches for collecting outdoor Aedes albopictus in China
Authors: Wu Yuyan , Hou Juan , Liu Qinmei , Wang Jinna , Li Tianqi , Luo Mingyu , Gong Zhenyu 
Published: October 2023

AbstractDengue fever is one of the biggest threats to public health in China, causing huge disease burden and economic loss. Aedes-mosquito surveillance could be a cornerstone for predicting the risk of Aedes-borne diseases and evaluating the effect of vector management during diseases outbreaks. The human landing catch (HLC) method is regarded as the “gold standard” for catching Aedes mosquitoes, but it potentially exposes field professionals to vectors of known or unknown pathogens. Human-baited double net (HDN) was recommended to replace HLC for emergency monitoring in China when Aedes-borne diseases break out, but it had been reported with low efficiency for capturing Aedes mosquitoes. In this study, we compared HLC with HDN and BG traps for field Aedes albopictus monitoring, with the aim of evaluating the effectiveness of HDN replacing HLC and finding an effective and safe alternative to the HLC for monitoring Aedes albopictus. Six sites in Hangzhou, Shaoxing, and Yiwu, Zhejiang Province, China, were chosen to conduct outdoor HLC, HDN, and BG trap catches from June to October 2021. The tests were performed 3 h apart: 8:30–9:30 AM, 16:30–17:30 PM, and 17:30–18:30 PM. A total of 2330 adult mosquitoes were collected, and Aedes albopictus was the most abundant species in all three catches with 848(98.95%), 559(97.39%) and 867 (96.44%) caught in HLC, HDN and BG traps respectively. Compared to HLC, HDN collected significantly less Ae. albopictus and Ae. albopictus females per trapping period (P < 0.001, P < 0.001), whereas no statistical differences were found between the HLC and BG trap (P = 0.970, P > 0.05). Statistically significant positive spatial correlations for Ae. albopictus sampling was found between HLC and HDN traps (r = 0.543, P < 0.001) and HLC and BG traps (r = 0.658, P < 0.001). In conclusion, both the BG trap and HDN have a significant positive spatial correlation with HLC, making them safer alternatives to HLC for Ae. albopictus monitoring in China. However, with better a sampling efficiency, being less labor intensive, and no human-baited attraction bias, the BG trap could be a better choice than the HDN trap.
A scoping review linking early childhood caries to violence, neglect, internally displaced, migrant and refugee status
Authors: Folayan Morenike Oluwatoyin , Schroth Robert J. , Ayouni Imen , Nguweneza Arthemon , Arheiam Arheiam , Al-Batayneh Ola B. , Virtanen Jorma I. , Gaffar Balgis , Duangthip Duangporn , Sun Ivy Guofang , Mohebbi Simin , Feldens Carlos A. , Tantawi Maha El 
Published: October 2023

Abstract
Background
The aim of the scoping review was to identify and synthesize the available literature concerning the relationship between the status of refugees, migrants, and internally displaced persons (IDPs) and Early Childhood Caries (ECC) as it relates to the United Nation’s Sustainable Development Goal 16 (SDG 16).

Methods
Data regarding the links between the status of refugees, migrants, and internally displaced persons (IDPs) and Early Childhood Caries (ECC), and the associations between ECC and maternal and child exposure to physical and sexual abuse, insecurity, crime, exploitation, torture, and displacement were extracted. The search was carried out in January 2023 across three databases (PubMed, Web of Science, and Scopus). Only publications in English with accessible full texts were included. Descriptive statistics were utilized to summarize the categories of the retrieved papers, and graphical representation was employed for visualization purposes. The relationships between the publications and each of the 10 targets of Sustainable Development Goal 16 (SDG 16) were also assessed.

Results
Forty-five studies were reviewed. Most studies (42.2%) originated from the Americas Regions, while no studies were identified from the Africa Region. A significant portion (46.7%) of the papers focused on abuse, violence, and neglect as risk factors for ECC. Migrants, refugees, and IDPs were the most investigated populations (44.4%). Only one study specifically focused on IDPs and migrants respectively. The prevalence of untreated caries was higher among migrants, refugees, and IDPs compared to the host community, ECC was more prevalent among children who experienced abuse, neglect, or were in protective care. The was no clear direction on the associations between ECC and intimate partner violence, adverse childhood experiences, and wars. In terms of the SDGs, the reviewed publications addressed four targets (SDG16.1, SDG16.2, SDG16.3, and SDG16.5) out of the ten targets outlined in SDG 16.

Conclusion
There is available evidence regarding the connections between ECC and war, refugees, migration, violence, and neglect, as outlined in SDG 16. Future studies are needed to investigate how forced movements directly affects ECC status, how disruptions of peace and stability is a risk factor for ECC, and the associations between ECC and other indicators related to SDG 16 targets.
The effect of secondhand smoke exposure on dental caries and gingival health among schoolchildren in Damascus, Syria: a cross-sectional study
Authors: Misrabi Ghalia , Karkoutly Mawia , Bshara Nada 
Published: October 2023

Abstract
Objective
This study aimed to evaluate the effect of secondhand smoke on dental caries and gingival health among schoolchildren in Damascus, Syria.

Materials and methods
This was a cross-sectional study. It was carried out at government schools in Damascus, Syria. This study included healthy children aged 10 to 13 years old. Schoolchildren were interviewed to answer the researcher-administered questionnaire to obtain answers regarding demographic information and family smoking behavior. A dental examination was performed by a dentist, and the number of decayed (D), missing (M), and filled (F) permanent teeth (DMFT) was scored based on the World Health Organization (WHO) 1997. A gingival examination was performed using the modified gingival index (MGI) and Silness-Leo plaque index (PI) to assess gingival inflammation and plaque accumulation, respectively.

Results
A total of 284 schoolchildren participated. More than half (61.26%) of them were exposed to secondhand smoke (SHS), and about half of them (52.11%) resided in a house with at least one cigarette smoked in a day. About one-third of the passive smokers (33.30%) had poor plaque control, with a statistically significant difference from non-passive smokers (p < 0.05). The multivariate regression model showed that the number of smokers at home was significantly associated with the DMFT score, dental plaque accumulation, and gingival inflammation (p < 0.1). However, the number of cigarettes smoked at home in a day was not a predictor for dental caries and gingival status (p = 1.000).

Conclusions
Within the limitations of this study, the number of smokers at home appears to have more adverse effects on children’s oral health compared to the quantity of smoke inhaled. In addition, SHSe was associated with more dental plaque accumulation among schoolchildren.
Design and evaluation of blended teaching in the smart classroom combined with virtual simulation training in basic nursing courses
Authors: Meng Ya , Song Jian , Yu Xiaojing , Xu Xiaoxia , Zhang Hao 
Published: October 2023

Abstract
Objective
This study explored the application effect of smart classrooms combined with virtual simulation training in basic nursing courses for nursing undergraduates.

Methods
In this quasi-experimental study, a total of 135 undergraduate nursing students in the 2021 matriculating cohort were selected as the research subjects. The experimental group of Class 1 had 71 students, and a blended teaching design utilizing a smart classroom and virtual simulation training was adopted. The control group of Class 2 had 64 students, and traditional lecture-based teaching design was adopted. After the course, the independent learning ability scale, test scores and teaching effectiveness questionnaire were used to evaluate the teaching effect. All tests had a maximum score of 100.

Results
Nursing undergraduates in the experimental group had scores of 86.32 ± 8.25 for virtual simulation training and 84.82 ± 9.04 for peer-assisted learning. The scores of the theoretical examination, experimental examination, and subjective questions in the experimental group were significantly higher than those in the control group (P < 0.05). The approval rate of nursing undergraduates in the experimental group was significantly higher than that of the control group for four items (Ps < 0.05). Among the 71 students, most students (91.55%) claimed that the use of instructional designs increased the fun of the classroom. In addition to the dimension of information literacy, the total score of independent learning ability and the other three dimensions of the experimental group were significantly higher than those of the control group (P < 0.05).

Conclusion
The teaching design combining smart classrooms and virtual simulation training can be applied to realize online blended teaching and classroom informatization, improving the academic performance and independent learning ability of nursing undergraduates, and thus achieving good teaching effects.
Clinical teaching in applied health science: effects of a student-led journal club on aging and physical activity
Authors: Fleiner Tim , Trumpf Rieke , Schnorr Thiemo , Buchner Theresa , Haussermann Peter , Zijlstra Wiebren , Morat Tobias 
Published: October 2023

Abstract
Background
This project aims to investigate the effects of a student-led journal club on students’ critical thinking and clinical application skills in the academic field of aging and physical activity.

Methods
A pre-post design analysis with data collected in four successive cohorts of the program M.Sc. Sport and Movement Gerontology was conducted. Each student assigned himself/herself to a study, and then led the journal club discussion and published a summary of the journal club via graphical abstract on social media. The students rated their perceived confidence in the beginning (T0) and after the semester (T1) via questionnaire and 5-point Likert scales addressing their ability to review and summarize the evidence, to present it in a journal club and to lead the discussion.

Results
41 students (32 women, M = 25 years SD 1.9 years) were included. The journal club was rated as “very good” (median 2, IQR 1). Students’ confidence on participating, leading the journal club and transferring the results into clinical practice improved significantly (r ≥ 0.6, p < 0.01) – e.g.: “I feel confident in leading a discussion on the literature presented”, T0: “undecided” (median 3, IQR 2) to T1: “rather agree” (median 4, IQR 1, Z= -5.41, r = 0.85, p < 0.01).

Discussion
The student-led journal club shows to be an effective teaching approach for the field of aging and physical activity within applied health science education. Especially the students’ self-assignment to the studies and involving the scientific community via social media was rated as useful and highly motivating for students and lecturers.