bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, characterisation, in silico & in vitro anti-cholinesterase activity of some novel 2 amino 5-substituted oxadiazoles
Authors: Suchitra M. , Kiranmai A. , Deepika P. , Joshna K. 
Published: January 2025

An individual with Alzheimer's disease (AD) experiences cognitive decline, memory loss, and behavioral abnormalities. The complex condition known as AD is brought on by acetylcholinesterase (AChE), which breaks down acetylcholine. The current investigation aimed to evaluate synthetic AChE inhibitors that may be utilized to treat AD. To do this, synthetic two amino five substituted oxadiazole derivative compounds (1a-5e) were assessed and shown to be potential AChE inhibitors, with IC50 values ranging from 73 ± 0.67 to 98 ± 0.7 µmol/min/mg of tissue. In silico docking investigations were performed using Schrodinger, revealing that most of the compounds are held together by ?–? and hydrogen bonding and interact with the anionic subsite of AChE. Chem Bio Draw Ultra 12.0 (www.cambridgesoft.com) was used to create the 2D structures of each drug. 2. The RSC PDB (www.rscb.org) provided the crystallographic three-dimensional structure of AChE target receptors, with PDB ID: 4EY5 &604 w for AChE. The most potent compound is 5e; consequently, these compounds can potentially be used as therapeutic agents to treat AD and its related conditions because of their AChE inhibitory capacity cytotoxicity safe profile.
Evaluation of Pesticide Effects on Honeybee Health and Colony Collapse: Findings from a Beekeeper Survey in the Beni Mellal-Khenifra Region, Morocco
Authors: Brhich Amina , Hachimi Tarik , Chatoui Hicham , Ait Sidi Brahim Malika , Hnini Rachid , Chatoui Redouane , Merzouki Hasna , Merzouki Mohamed 
Published: January 2025

Since it first appeared in 2022, the phenomenon referred to as Colony Collapse Disorder (CCD) has affected several regions of Morocco to varying degrees. In order to assess the possible impact of pesticides on the appearance of this syndrome, we conducted a study aimed at evaluating the impact of pesticide use on the emergence of this syndrome through a year-long survey involving 160 beekeepers in the Beni Mellal–Khenifra Region (BKR) who also experienced an unprecedented desertion of hives during the same period. The majority of surveyed beekeepers practice mixed (45%) or migratory beekeeping (42%) and provide supplementary feeding (83.75%) to support their bees. Nearly 37.5% of the hives are located near crops treated with pesticides, exposing the bees to these chemicals. The results showed that the majority of beekeepers reported a cessation of queen laying (74.38%), high mortality rates among worker bees (81.25%), drones (65.63%), and queens (61.88%). Abnormal behaviors such as immobility with trembling (42.50%), reduced flights (47.50%), and disoriented navigation (28.75%) were also observed. Correlation analyses indicate that proximity to treated crops significantly increases the risk of queen laying cessation (Odds Ratio 6.0) and a reduction in waggle dances (Odds Ratio 2.41). Extended foraging flights show a borderline statistical significance (Odds Ratio 2.33), suggesting a disruption of natural food sources. These results highlight the potential impact of pesticides on colony health and bee behavior, pointing out the need to adapt beekeeping practices and implement protective measures against pesticides.
Digital-Based Religious Moderation: Analyszing Ustadz/Kyai’s Dakwah Content on Youtube
Authors: Shofiyuddin Haris , Alindah Lutfiyah , Juma’ Juma’ 
Published: January 2025

Abstract: YouTube serves as a media platform that offers not only knowledge and education but also a means for sharing religious content. However, not all religious content on YouTube conveys messages of religious moderation. There is a substantial amount of content that promotes rigidity and violence in understanding religion, potentially influencing individuals' religious attitudes. This study aims to explore religious moderation within the da'wah content of ustadz or kyai on Youtube. This qualitative research employs Van Dijk's discourse analysis approach. The study reveals that the da'wah content by Hanan Attaki, Adi Hidayat, Khalid Basamalah, and Gus Miftah predominantly incorporates pillars of thought by connecting the meanings of verses, hadiths, or historical contexts. The pillars of action are exemplified through acts of tolerance and wisdom in dealing with differences. The implementation of these pillars of religious moderation in their da'wah content is primarily confined to national commitment and the strengthening of tolerance.Keyword: moderation, Youtube, ustadz/kyai Abstrak: Youtube merupakan sebuah media platform yang tidak hanya menyuguhkan seputar pengetahuan atau pendidikan, tetapi juga sebagai sarana sharing agama. Namun, tentu tidak semua konten YouTube agama mengandung pesan-pesan moderasi beragama. Ada banyak konten YouTube yang justru menyuguhkan kekakuan dan kekerasan dalam memahami agama. Sehingga, akan berpengaruh terhadap sikap beragama seseorang. Dalam hal ini, penelitian ini berusaha memotret moderasi beragama dalam konten dakwah ustadz atau kyai di YouTube. Penelitian ini adalah penelitian kualitatif dengan pendekatan analisis wacana Van Dijk. Hasil penelitian menunjukkan bahwa konten dakwah yang disampaikan oleh Hanan Attaki, Adi Hidayat Khalid Basamalah, dan Gus Miftah lebih banyak menerapkan pilar pemikiran, yaitu dengan mengkaitkan makna ayat, hadist, atau bahkan sejarah. Sedangkan pilar perbuatan lebih pada percontohan hablum minannas, baik bersikap toleransi maupun bijak dalam perbedaan. Adapun implementasi dari pilar-pilar moderasi agama dalam konten dakwah ini adalah pada batas komitmen bernegara dan penguatan toleransi semata.Kata Kunci: Moderasi, Youtube, ustadz/kiai
Patterns of Relations between Adolescents and Parents and Their Impact on Religious Moderation Attitudes (Case Studies in Bali and Madura)
Authors: Sahari Sahari , Gunawan Edi , Aisa Siti , Tohis Reza Adeputra 
Published: January 2025

Abstract: This study aims to examine the patterns of relationships between adolescents and parents and their influence on the attitudes toward religious moderation among student adolescents in Bali's multicultural society and Santri adolescents in Madura's religious and homogeneous society. This research employs a quantitative research method with a survey approach. The results indicate that the relationship between parents and adolescent students in Bali and Madura shows a very good pattern, with an average score of 53.88. There are differences in the patterns of relationships between adolescents and parents in Madura and Bali. In Madura, the adolescent-parent relationship demonstrates authoritarian and democratic patterns, while in Bali, it shows permissive and neglectful patterns. The democratic relationship pattern has the highest average value compared to other relationship patterns. Overall, relationship patterns have a significant positive correlation with religious moderation among adolescents in Madura and Bali.Keywords: Relationship Patterns; Adolescents and Parents; Religious Moderation; Multicultural Abstrak: Penelitian ini bertujuan mengkaji pola relasi remaja dan orangtua serta pengaruhnya terhadap sikap moderasi beragama remaja pelajar pada masyarakat Bali yang multikultural dan remaja santri pada masyarakat Madura yang religius dan homogen. Penelitian ini menggunakan metode penelitian kuantitatif dengan pendekatan survei. Hasil penelitian menunjukan bahwa relasi antara orang tua dan remaja pelajar di Bali dan Madura memiliki pola yang sangat baik dengan skor rata-rata 53,88. Terdapat perbedaan pola relasi remaja dan orang tua pada masyarakat Madura dan Bali. Di Madura relasi remaja-orang tua menunjukkan pola otoriter dan demokratis, sedangkan di Bali menunjukan pola permisif dan abai. Pola relasi demokratis memiliki nilai rata-rata paling tinggi dari pola relasi yang lain. Secara keseluruhan pola relasi memiliki hubungan positif yang signifikan dengan moderasi beragama pada remaja di Madura dan Bali.Kata Kunci: Pola Relasi; Remaja dan Orang Tua; Moderasi Beragama; Multikultural
APPRECIATE BUT NOT ACKNOWLEDGE: (State Construction Towards Religion and Regulations with Discriminatory Nuances)
Authors: Indara Rona , Mantu Rahman 
Published: January 2025

Abstract: The meaning and recognition of religions in Indonesia are closely related to politics. Political sentiment during the transition of power from the old order to the new order affects how the State interprets religion in the constitution. Especially during the New Order period, minority religions or beliefs received discriminatory treatment, this fact was evidenced by various regulations that were impartial and protected minority religions and until now these policies continue to be used. The state, in this case, the government is intensively campaigning for the idea and practice of diversity, tolerance, and religious moderation, along with which there are many cases of violence and discrimination based on religious backgrounds. Using a socio-juridical approach, the author then found many regulations related to religion and beliefs that are still discriminatory and do not protect all citizens of the nation, as mandated by the 1945 Constitution.Keywords: Religion, Regulation, Discrimination, Diversity, Government.Abstrak : Pemaknaan dan pengakuan Agama-agama di Indonesia sangat berkait erat dengan Politik. Sentimen politik saat peralihan kekuasaan dari orde lama ke orde baru berpengaruh terhadap bagaimana Negara memaknai Agama di dalam konstitusi. Terlebih di masa Orde baru agama atau kepercayaan minoritas mendapatkan perlakuan yang diskriminatif, fakta itu dibuktikan dengan berbagai macam regulasi yang tidak berpihak dan melindungi agama minoritas dan sampai sekarang kebijakan-kebijakan tersebut terus digunakan. Negara dalam hal ini pemerintah sedang gencar mengkampanyekan gagasan dan praktik kebhinekaan, toleransi, serta moderasi beragama, seiring dengan itu muncul banyak kasus kekerasan dan diskriminasi berlatar belakang agama. Dengan menggunakan pendekatan sosio-yuridis penulis kemudian menemukan banyak regulasi-regulasi berkaitan dengan agama dan kepercayaan yang masih bernuansa diskriminatif dan tidak melindungi segenap warga bangsa, sebagaimana amanat UUD 1945.Kata Kunci: Agama, Regulasi, Diskriminatif, Kebhinekaan, Pemerintah.
ANALISIS KECEPATAN GELOMBANG GESER (Vs) MENGGUNAKAN MULTICHANNEL ANALYSIS OF SURFACE WAVE (MASW) DI KECAMATAN JAMBI LUAR KOTA
Authors: Musyarofah Leni Nurli , Resta Ichy Lucya , MZ Nasri 
Published: January 2025

Kecamatan Jambi Luar Kota merupakan salah satu kecamatan dengan tingkat kepadatan masyarakat dan pembangunan yang terus meningkat yang dapat dilihat selama 10 tahun terakhir (2010-2020) yaitu 39 jiwa per-Km2. Pembuatan peta kelas tanah perlu dilakukan sebagai bahan pertimbangan pembangunan infrastruktur dengan memperhatikan aturan pembangunan yang sesuai dengan SNI 1726-2012. Penelitian menggunakan metode Multichannel Analysis Of Surface Wave (MASW) yang mengukur variasi kecepatan gelombang permukaan sebagai sinyal utamanya dengan jumlah lintasan sebanyak 21 (L01-L21). Nilai rata-rata kecepatan gelombang geser dikedalaman 30 m pengukuran MASW berkisar 153.24 m/s – 420.86 m/s yang terdiri dari kelas tanah SC, kelas tanah SD dan kelas tanah SE. Kelas tanah SC dengan nilai Vs30 sebesar 358.88 m/s 420.86m/s terdapat di 3 lokasi penelitian yaitu L01, L03 dan L04. Sedangkan kelas tanah SD tersebar merata di Kecamatan Jambi Luar Kota. Untuk kelas tanah SE terdapat di L13 dan L07 dengan nilai Vs30 sebesar 153.24 m/s yang dalam hal ini didukung oleh data geoteknik berupa kadar air (w) (43.03%), indeks plastisitas (PI) (23.26) dan uji kuat geser sebesar 17.652 kPa. Apabila dilihat dari nilai Vs30 yang rendah, maka daerah ini merupakan daerah yang berpotensi untuk mendapatkan guncangan yang relatif lebih besar ketika terjadi pergerakan tanah.
El screen tourism y su relación con los referentes culturales en la serie de ficción Emily in Paris, temporada 1 (Netflix, 2020)
Authors: Sánchez-Martínez Josefina , Sarabia-And´úgar Isabel 
Published: January 2025

Introducción: El binomio turismo-cine (turismo inducido o turismo de pantalla) ha sido ampliamente investigado, desde que, en el año 1992, Riley y Van Doren vincularan las dos industrias y vaticinaran su repercusión positiva en la economía. Uno de los recursos susceptibles de reforzar los lazos entre pantalla y turismo, aún por abordar en los estudios sobre screen tourism, es el de “referentes culturales”, directamente relacionados con la “afinidad cultural”. El objetivo de esta investigación es reflexionar sobre el uso de este componente en la trama de una ficción audiovisual como factor para acercar los rasgos distintivos de una comunidad al espectador y generar así en él un mayor interés que podría derivar en una visita turística al lugar representado. Metodología: Se elabora una ficha de análisis que sirve para identificar los referentes culturales en la primera temporada de la serie Emily in Paris. Resultados: La información se presenta en cuatro niveles: narratológico, icónico, psicoanalítico y experiencial. Discusión: Se constata que Emily in Paris es un paradigma en la construcción de la narración a través de referentes culturales. Conclusiones: La inclusión de referentes culturales en una serie, utilizada como estrategia para fomentar el turismo, solo puede ser efectiva si la trama es contemporánea al espectador y si las localizaciones mencionadas son reales.
Infraestructura portuaria, ferroviaria, almacenamiento y el transporte terrestre y aéreo de carga y por tuberías tienen un impacto económico en Panamá
Authors: Valverde Batista Reyes Arturo 
Published: January 2025

Introducción: El sistema multimodal está compuesto por un diverso conjunto de infraestructura, equipos y maquinaria, orientado a satisfacer operaciones de manejo, almacenamiento y transbordo de carga. Metodología: Se requiere de las Tablas Input-Output 2019 y 2020, cuya dimensión es 45X45, elaboradas a partir de los Cuadros de Oferta y Utilización publicados por el Instituto Nacional de Estadística y Censo (INEC), el 8 de febrero de 2023 y cuya denominación es “Sistema de Cuentas Nacionales de Panamá, nuevas series preliminares con año de referencia 2018: Años 2018-21”. A la vez, se utilizan los datos de la Encuestas Entre Empresas No Financieras (EEENF), para el 2019 presentados por el INEC el 6 de junio de 2022 y EEENF para el 2020 publicados el 13 de junio de 2022. Resultados: Apuntan a superar el 4% en producción, mientras que en el VAB hay una horquilla entre el 2.6% y 3%; por su parte en empleos este conglomerado produce entre 43 y 59 mil en los años analizados. Discusión: Se constata la importancia del sistema multimodal en la economía panameña al ser parte de la ventaja comparativa de la plataforma de servicios. Conclusión: Se concluye que este grupo de servicios tiene un peso económico relevante.
La forma del agua: influencia o referencia. Andrei Tarkovski y Guillermo del Toro
Authors: Flores García Laura Gemma 
Published: January 2025

Introducción: En este estudio se comparan dos filmes artísticos: El espejo (Zerkalo) (1975) de Andrei Tarkovski y La forma del agua (2018) de Guillermo del Toro. Metodología: Basándonos en el análisis del lenguaje visual, encontramos mensajes subyacentes que coinciden en ambas obras. Resultados: En el año de 1975, El Espejo de Tarkovsky fue proyectada en el Festival de Moscú y al pasar de los años sus recursos estéticos sentaron un precedente, hasta el grado de que el estreno de La forma del agua parece haber recogido algunas referencias que los hacen confluir en recursos visuales y simbólicos que, para nuestra época, se han convertido en clichés artísticos. Discusión: Deshilvanando los recursos de ambos filmes, fuimos encontrando paradigmas visuales que nos permitieron tocar aguas más profundas. Basándonos en la crítica filosófica de Gilles Deleuze a partir de su ensayo Diferencia y repetición, analizamos el trasvase e interdependencia entre los principios gnoseológicos de una y otra producción. Conclusiones: Los recursos visuales de ambas películas se presentan como una conciencia filogenética del hombre y son razones para presentar un análisis –a través del teórico Gilles Deleuze- de los posibles hilos conductores de dos momentos relevantes de la historia del cine.
Legal Analysis of the Determination of the Age Limit of Children Related to Sexual Crimes Committed by Children (ABH) in the Perspective of Law Enforcement in Indonesia and International Law
Authors: Sumartini Raden Siti , Hamja Hamja , Fathurrahman Farhan 
Published: January 2025

The development of sexual crimes against children, both children as perpetrators or children as victims lately is very concerning. Sexual crimes are greatly influenced by time and place. The high level of human civilization and the phenomenon of globalization that increasingly knows no boundaries, in this case, is the negative impact of the influence of globalization also contributes to the emergence of various crimes of sexual harassment. Often crimes or criminality occur around our lives, including on the streets or public spaces. From the presentation, the formulation of the problem will arise, namely how is the Status and Position of Children in the positive legal system of Indonesia and International Law? What is the form of legal protection for children who have committed criminal acts in Indonesia's positive law? How is the concept of legal reform on the determination of children's age limits so that they can make a positive contribution to law enforcement?
The methodology used in the study uses a normative legal research method (doctrinal research) which mainly analyzes primary legal materials and secondary legal materials, in this case the researcher also complements the method of interviewing sources that is autorotac, because its nature is more focused on conceptualizing ideas in the form of models, so that the expected results can be applied by policy makers. Violations of the law that have been committed by a child, of course, in terms of law enforcement, are treated differently (diversion) from the procedures applied by adults. Therefore, researchers argue that there is a shift in understanding related to the age of children and people who are considered adults at this time, remembering the fact that some children are not yet 18 years old, but they are physically and psychologically mature. Based on the above explanation, according to the author, it is important to be able to conduct a study on the age limit of children so that they are limited legal subjects because this can be a measure for law enforcement and can provide legal protection for children who are facing the law.
Tutorial on Fourier Transform for Ultrafast Optics
Authors: Chen Yi-Hao 
Published: January 2025

This tutorial is designed for individuals who are new to the field of ultrafast optics. It was written in response to the apparent lack of comprehensive introductions to the basic Fourier transform, extending beyond the flat-phase description. Additionally, there is a need for complete derivations of several relations involving the Fourier transform, maintaining its most general formulation. This approach avoids the arbitrary selection of Fourier-transform constants and ensures a complete understanding. It shows the importance of having Fourier-transform constants as parameters, which I would like to advocate people to do. Most important of all, I have seen misuse of Fourier transform over my years of discussion in the lab and from others’ questions since I shared my code publicly on Github [https://github.com/AaHaHaa/MMTools]. Surprisingly, since people check the correctness of numerical implementation only by seeing if the simulation result is smooth and if it duplicates the “overall physics,” this seems to be a widespread problem from my perspective, which can be solved by a simple tutorial (see Sec. 2B). This is why I hope that this tutorial can help people understand more about the Fourier transform, especially in the context of ultrafast optics.

Feel me to send me an email if there is any confusion, or you think that there is more to add to this tutorial.
Faktor-Faktor yang Mempengaruhi Potensi Pupuk Organik Dalam Pertanian Raman Lingkungan Berkelanjutan (PRLB) di Kabupaten Ngawi
Authors: Sujito Sujito , Talkah Abu , Suparno Suparno 
Published: January 2025

Pertanian Ramah Lingkungan saat ini telah berkembang secara luas, baik dari sisi budidaya, sarana produksi, jenis produk, pemasaran, pengetahuan konsumen, dan organisasi/lembaga masyarakat yang menaruh minat pada pertanian organik. Tujuan penelitian ini untuk mengetahui faktor yang mempengaruhi potensi petani terhadap penggunaan pupuk organik yaitu faktor internal dan faktor eksternal. Faktor internal seperti usia petani, pendidikan formal petani serta pendidikan non formal petani. Metode penelitian kualititaf. Penelitian ini dilaksanakan di Kecamatan Pitu Kabupaten Ngawi. Selama empat bulan mulai dari Bulan April sampai Agustus 2023. Informan dalam penelitian ini sebanyak 20 orang petani. Hasil dari penelitain ini adalah faktor internal tesebut dapat mendukung keberhasilan usahatani, sementara pada faktor eksternal yang mempengaruhi respon petani yang ada di Kecamatan Pitu, Kabupaten Ngawi yakni manfaat yang di harapkan, selang waktu antara awal penggunaan dengan memperoleh manfaat dan enersi/korbanan yang dikeluarkan, kendala yang masih ada di lapangan beberapa petani masih ada yang ketergantungan pada pupuk kimia, dan di sisi lain kurangnya apresiasi terhadap produk â€“produk organik dari hasil panen.
Kelayakan Non Finansial Sistem Pembelian Tebu Putus Terhadap Jumlah Bahan Baku Pabrik Gula Tjoekir
Authors: Mashudiana Mashudiana , Mulyaningtyas Ratna Dewi , Askafi Eka 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui kelayakan non finansial sistem pembelian tebu putus terhadap jumlah bahan baku PG Tjoekir. Penelitian ini dilaksanakan di PG Tjoekir dalam waktu 2 Bulan yaitu pada Bulan Agustus â€“ September 2023. Metode analisis menggunakan analisis kualitatif dengan mendeskripsikan kelayakan non-finansial meliputi aspek pasar, aspek teknis, aspek manajemen, dan aspek lingkungan. Metode Pengambilan data dengan data primer yaitu wawancara, observasi lapangan, dan data sekunder dari internet, data dari PG Tjoekir. Hasil penelitian menunjukkan bahwa Kelayakan non finansial berpengaruh terhadap jumlah bahan baku tebu di PG Tjoekir. aspek pasar, teknis, manajemen, dan lingkungan berpengaruh terhadap jumlah bahan baku tebu
Pengaruh Disiplin, Motivasi Kerja Dan Kerjasama Tim Terhadap Kinerja (e-Kinerja) DiKantor Polsek Ngantru Kabupaten Tulungagung
Authors: Sumaji Sumaji , Arisyahidin Arisyahidin , Rusandy Deby Satyo 
Published: January 2025

The purpose of this research is to know and analyze the influence of discipline, the team work and cooperation on performance in ( e-kinerja ) Ngantru Police Tulungagung District. This study using descriptive quantitative methods. With a population and those members of the Police Ngantru District Tulungagung totaling 28 respondents. A method of collecting the data using a questionnaire, literature and methods of observation field. While the data analysis using analysis linear regression.
The results of this study show that discipline, work motivation and teamwork against performance (e-kinerja). It is supported by the result of r square or coefficient determination (KD ) shows 83.8 % so interpreted if variable X1 (work discipline ), X2 (work motivations) and X3 (team cooperation ) have a contribution of 83.8 % to variable Y the performance (e-kinerja ) and 16.2% others are influenced by other factors besides variable X. In addition, in the f count 18,077 receive is worth of 0,000 sig. Thus showing that the f count greater than f table or 18,077 > 2,99 with the sig 0,000< 0,05 Thus received hypothesis, while on the outcome of the t known for partial that discipline, the team work and cooperation on performance ( e-kinerja ) Ngantru Police Officer At Tulungagung District.