bluuebunny/crossref_metadata_2025_split huggingface dataset:
Woven EndoBridge Device for Unruptured Wide-Neck Bifurcation Aneurysm: A Multicenter 5-Year Follow-up
Authors: Semeraro Vittorio , Palmisano Vitanio , Limbucci Nicola , Comelli Simone , Comelli Chiara , Ganimede Maria Porzia , Lozupone Emilio , Barone Michele , Marrazzo Antonio , Paladini Andrea , della Malva Giuseppina , Briatico Vangosa Alessandra , Laiso Antonio , Renieri Leonardo , Capasso Francesco , Gandini Roberto , Di Stasi Carmine , Resta Maurizio , Mangiafico Salvatore , Burdi Nicola 
Published: December 2023

BACKGROUND AND OBJECTIVES:
This multicenter study aimed to assess the safety and efficacy of the Woven EndoBridge (WEB) device for treating unruptured wide-neck intracranial bifurcation aneurysms (WIBAs) with short-, mid-, and long-term follow-ups (FUPs).

METHODS:
Consecutive patients with unruptured WIBAs treated with WEB between December 2014 and January 2018 were included. Patient, aneurysm, and device characteristics were collected and analyzed retrospectively. Morbidity and mortality rates were determined by collecting intraprocedural, periprocedural, and delayed complications. Aneurysm occlusion was assessed at 1, 3, and 5 years using a 3-grade scale: complete occlusion, neck remnant, and residual aneurysm. Complete occlusion and neck remnant were considered as adequate occlusion. Patients who received re-treatment were also evaluated.

RESULTS:
The study included 104 consecutive patients (55.8% female, mean age 58.6 ± 11.8 years). Aneurysm maximum size, neck, and dome-to-neck mean were, respectively, 6.9 ± 2.1 mm, 4.5 ± 1.2 mm, and 1.4 ± 0.3 mm. One-year FUP was collected for 95 patients, and 3- and 5-year FUPs were collected for 83 patients. Adequate occlusion was observed at 1-year FUP in 90.5% (86/95), 91.6% (76/83) was observed at 3-year FUP, and 92.8% (77/83) at 5-year FUP. None of the aneurysms bled after treatment. During FUP, 6/83 patients (7.2%) were re-treated for residual aneurysm. Morbidity and mortality rates closely related to aneurysm occlusion were 0% (0/104).

CONCLUSION:
The WEB device was safe and effective for treating unruptured WIBAs, both in short-term and long-term FUPs.
Superiority of Endovascular Coiling Over Surgical Clipping for Clinical Outcomes at Discharge in Patients With Poor-Grade Subarachnoid Hemorrhage: A Registry Study in Japan
Authors: Ishikawa Tatsuya , Ikawa Fusao , Ichihara Nao , Yamaguchi Koji , Funatsu Takayuki , Nakatomi Hirofumi , Shiokawa Yoshiaki , Sorimachi Takatoshi , Murayama Yuichi , Suzuki Kaima , Kurita Hiroki , Fukuda Hitoshi , Ueba Tetsuya , Shimamura Norihito , Ohkuma Hiroki , Morioka Jun , Nakahara Ichiro , Uezato Minami , Chin Masaki , Kawamata Takakazu 
Published: December 2023

BACKGROUND AND OBJECTIVES:
The differences in clinical outcomes between endovascular coiling (EC) and surgical clipping (SC) in patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH) are controversial. Therefore, this study aimed to evaluate whether EC is superior to SC and identify risk factors in patients with poor-grade aSAH.

METHODS:
We used data from the “Predict for Outcome Study of aneurysmal SubArachnoid Hemorrhage.” World Federation of Neurological Societies (WFNS) grade III–V aSAH was defined as poor-grade aSAH, and unfavorable clinical outcomes (modified Rankin Scale scores 3-6) were compared between SC and EC after propensity score matching (PSM). In-hospital mortality was similarly evaluated. Predictors of unfavorable clinical outcomes were identified using multivariable analysis.

RESULTS:
Ultimately, 1326 (SC: 847, EC: 479) and 632 (SC: 316, EC: 316) patients with poor-grade aSAH were included before and after PSM, respectively. Unfavorable clinical outcomes at discharge were significantly different between SC and EC before (72.0% vs 66.2%, P = .026) and after PSM (70.6% vs 63.3%, P = .025). In-hospital mortality was significantly different between groups before PSM (10.5% vs 16.1%, P = .003) but not after PSM (10.4% vs 12.7%, P = .384). Predictors of unfavorable clinical outcomes in both SC and EC were WFNS grade V, older than 70 years, and Fisher computed tomography (CT) grade 4. Predictors of unfavorable clinical outcomes only in SC were WFNS grade IV (odds ratio: 2.46, 95% CI: 1.22-4.97, P = .012) and Fisher CT grade 3 (4.90, 1.42-16.9, P = .012). Predictors of unfavorable clinical outcome only in EC were ages of 50s (3.35, 1.37-8.20, P = .008) and 60s (3.28, 1.43-7.52, P = .005).

CONCLUSION:
EC resulted in significantly more favorable clinical outcomes than SC in patients with poor-grade aSAH, without clear differences in in-hospital mortality. The benefit of EC over SC might be particularly remarkable in patients with WFNS grade IV and Fisher CT grade 3.
How to Estimate the Sigma Level of the Process
Authors: Terek Milan 
Published: December 2023

Purpose: This paper proposes a procedure for estimating the sigma level of the process through a confidence interval.
Methodology/Approach: The approach is based on a model in which the process has a normal distribution and constant variance, and its mean is shifted to the right or left by 1.5 standard deviations.
Findings: The paper explains a method for creating a random sample along with determining the sample size to estimate the “defects per million opportunities” characteristic through a confidence interval. Based on it, the confidence interval for the “sigma level” of the process is determined.
Research Limitation/implication: We assume a discrete process in which n pieces of the product are selected. The proposed procedure assumes that the process is in statistical control.
Originality/Value of paper: Applying the proposed random sampling and estimation procedure can improve evaluations of process performance, aiding decision-making for Six Sigma projects.
Proximity and Flatness Bounds for Linear Integer Optimization
Authors: Celaya Marcel , Kuhlmann Stefan , Paat Joseph , Weismantel Robert 
Published: December 2023

This paper deals with linear integer optimization. We develop a technique that can be applied to provide improved upper bounds for two important questions in linear integer optimization. Given an optimal vertex solution for the linear relaxation, how far away is the nearest optimal integer solution (if one exists; proximity bounds)? If a polyhedron contains no integer point, what is the smallest number of integer parallel hyperplanes defined by an integral, nonzero, normal vector that intersect the polyhedron (flatness bounds)? This paper presents a link between these two questions by refining a proof technique that has been recently introduced by the authors. A key technical lemma underlying our technique concerns the areas of certain convex polygons in the plane; if a polygon [Formula: see text] satisfies [Formula: see text], where τ denotes [Formula: see text] counterclockwise rotation and [Formula: see text] denotes the polar of K, then the area of [Formula: see text] is at least three. Funding: J. Paat was supported by the Natural Sciences and Engineering Research Council of Canada [Grant RGPIN-2021-02475]. R. Weismantel was supported by the Einstein Stiftung Berlin.
No difference in patient-reported outcomes with cruciate-retaining, anterior-stabilized, and posterior-stabilized total knee arthroplasty designs
Authors: Rehman Yasser , Korsvold Ann M. , Lerdal Anners , Aamodt Arild 
Published: December 2023

AimsThis study compared patient-reported outcomes of three total knee arthroplasty (TKA) designs from one manufacturer: one cruciate-retaining (CR) design, and two cruciate-sacrificing designs, anterior-stabilized (AS) and posterior-stabilized (PS).MethodsPatients scheduled for primary TKA were included in a single-centre, prospective, three-armed, blinded randomized trial (n = 216; 72 per group). After intraoperative confirmation of posterior cruciate ligament (PCL) integrity, patients were randomly allocated to receive a CR, AS, or PS design from the same TKA system. Insertion of an AS or PS design required PCL resection. The primary outcome was the mean score of all five subscales of the Knee injury and Osteoarthritis Outcome Score (KOOS) at two-year follow-up. Secondary outcomes included all KOOS subscales, Oxford Knee Score, EuroQol five-dimension health questionnaire, EuroQol visual analogue scale, range of motion (ROM), and willingness to undergo the operation again. Patient satisfaction was also assessed.ResultsPatients reported similar levels of pain, function, satisfaction, and general health regardless of the prosthetic design they received. Mean maximal flexion (129° (95% confidence interval (CI) 127° to 131°) was greater in the PS group than in the CR (120° (95% CI 121° to 124°)) and AS groups (122° (95% CI 120° to 124°)).ConclusionDespite differences in design and constraint, CR, AS, and PS designs from a single TKA system resulted in no differences in patient-reported outcomes at two-year follow-up. PS patients had statistically better ROM, but the clinical significance of this finding is unclear.Cite this article: Bone Joint J 2023;105-B(12):1271–1278.
ROTATOR CUFF TEAR IN FRACTURE SHOULDER DISLOCATION
Authors: Elgendy M , Makki D , White C , ElShafey A 
Published: December 2023

IntroductionWe aim to assess whether radiographic characteristics of the greater tuberosity fragment can predict rotator cuff tears inpatients with anterior shoulder dislocations combined with an isolated fracture of the greater tuberosity.MethodsA retrospective single-centre case series of 61 consecutive patients that presented with anterior shoulder dislocations combined with an isolated fracture of the greater tuberosity between January 2018 and July 2022. Inclusion criteria: patients with atraumatic anterior shoulder dislocation associated with an isolated fracture of the greater tuberosity with a minimum follow-up of 3-months. Exclusion criteria: patients with other fractures of the proximal humerus or glenoid. Rotator cuff tears were diagnosed using magnetic resonance or ultrasound imaging. Greater tuberosity fragment size and displacement was calculated on plain radiographs using validated methods.ResultsThe case series was composed of 22 men and 39 women with a mean age of 65 years (29 - 91 years). The mean follow-up was 15months and median follow up 8.5 months (3 – 60 months). A rotator cuff tear was diagnosed in 14 patients (16%) and involved the supraspinatus (13), infraspinatus (4) and subscapularis (2). Full-thickness tears occurred in 6 patients and partial-thickness tears in 8patients. The mean time from initial injury to rotator cuff tear diagnosis was 5 months (2 – 22 months).The mean greater tuberosity fragment length was 23.4 mm in rotator cuff tear patients versus 32.6 mm in those without a tear (p = 0.006, CI: -15 - -2). The mean greater tuberosityfragment width was 11.1 mm in rotator cuff tear patients versus 17.8 mm in those without a tear (p = 0.0004, CI: -10 - -2). There was no significant difference in the super inferior and anteroposterior fragment displacement between the two groups.ConclusionIn patients with shoulder dislocations combined with an isolated fracture of the greater tuberosity, rotator cuff tears are associated with a smaller sized greater tuberosity fragment.
Effects of the excitation wavelength and temperature on the zero-phonon emission line of Cr:YAG
Authors: Zheng Yuruo , Zhou Yimin , Zhang Debao , Ning Jiqiang , Tang Fei , Zheng Changcheng 
Published: December 2023

In this work, a detailed study was conducted of the temperature and excitation wavelength-dependent photoluminescence (PL) spectra of the chromium-doped yttrium aluminum garnet (Cr:YAG) transparent ceramic. Focusing on the two sets of zero-phonon lines (ZPLs) of the 2E→4A2 transition in this material, the PL spectra are discovered to evolve significantly with respect to temperature and be highly dependent on the excitation wavelength. Compared to the continuous variation behavior with temperature, an increase in the excitation wavelength leads to a blueshift of the peak position within the regions of 450 nm to 465 nm, 465 nm to 490 nm, and 490 nm to 500 nm, and a sharp change in the PL position at the excitation wavelengths of 465 nm and 490 nm. The electron–phonon coupling (EPC) effect is believed to be more sensitive to the excitation wavelength. Different excitation wavelengths involve different electronic levels participating in the light emission processes, which explains the evolution behavior of the PL peak position with respect to the excitation wavelength. Moreover, the emergence of weak peaks next to the ZPLs at particular temperatures and excitation wavelengths is also observed. This work compares the influence of the temperature and excitation wavelength to the PL properties of the Cr:YAG transparent ceramic, which promotes an advanced understanding of the luminescence behavior of the Cr:YAG transparent ceramics.
Cost analysis of ultrawideband transmission in optical networks
Authors: Souza André , Correia Bruno , Napoli Antonio , Curri Vittorio , Costa Nelson , Pedro João , Pires João 
Published: December 2023

We examine the cost associated with increasing traffic on a reference transport network for both single- and multiband systems, with a total transmission bandwidth ranging from 4.8 to 20 THz (S2 + S1 + C + L-band, where S2 and S1 are the two halves of the S-band). The number and cost of amplifiers, transceivers, and fibers are considered. To ensure stable transmission power and simplified network management, we take noise loading into account. The optimal combination of transmission bands—for each system—is evaluated based on the maximization of the capacity calculated from the minimum per-band generalized signal-to-noise ratio of each band. The results reveal that, despite the lower spectral efficiency due to the higher fiber attenuation and band MUX/DEMUX insertion losses, multiband systems can effectively reduce the number of fibers needed, thus postponing the deployment of new fibers. The most cost-effective solution depends on the fiber and S-band amplifier costs and the forecast of the required network capacity. When additional fibers are freely available or fiber costs are minimal, employing a C-band-only system proves to be the most economical choice. As fiber costs increase, additional bands gradually become more appealing, progressing from the C-band-only to the C + L-band, and then to the addition of half of the S-band (S1 + C + L-band) or the whole S-band (S2 + S1 + C + L). Furthermore, multiband transmission systems are more attractive when considering higher traffic loads. We also propose an optimal order of deployment of transmission bands in a pay-as-you-grow approach. The corresponding cost evolution demonstrates that this approach is a viable solution to mitigate excessive costs during the initial stages of a network operation, even though it leads to an increased number of fibers and transceivers used before all transmission bands are enabled. Additionally, we show that the S1- and S2-bands have worse optical performance, making them more suitable for shorter lightpaths. Consequently, operating the S-band in single-hop links and simplifying the add-drop multiplexer architecture could be beneficial.
Ensuring access to essential health products: Lessons from Colombia’s leishmaniasis control and elimination initiative
Authors: Vlassoff Carol , Giron Nora , Vera Soto Mauricio Javier , Maia-Elkhoury Ana Nilce Silveira , Lal Arush , Castellanos Luis Gerardo , Almeida Gisele , Lim Christopher 
Published: December 2023

Background
This paper identifies opportunities and challenges for leishmaniasis control and elimination in Colombia, emphasizing the role of pooled procurement of essential medicines and supplies. Colombia is among the countries most affected by leishmaniasis globally, and also faces the dual challenge of procuring critically needed medicines in the context of limited national resources. It recently renewed its commitment to the control and elimination of leishmaniasis under its 2022–2031 Public Health Plan (PDSP) through a comprehensive public health approach.

Methodology/Principal findings
The methodology comprises a comprehensive literature review and key informant interviews with leishmaniasis experts from the Colombian national control program and PAHO/WHO, focusing on cutaneous, mucocutaneous, and visceral leishmaniasis. Leishmaniasis is endemic throughout Colombia, with over 11 million people at risk, many of whom live in poverty-stricken, remote and isolated rural areas with limited access to health services. Leishmaniasis care, including medicines, is provided free of charge, but many barriers were nonetheless identified at environmental, population, and health system levels, including the supply of quality-assured medicines. Opportunities to alleviate these barriers were identified, including the support of the PAHO Strategic Fund. Within the context of the sustainable development goals and international leishmaniasis control and elimination targets, Colombian officials have established their own priorities, the highest of which is the reduction of deaths from visceral leishmaniasis.

Conclusions/Significance
The elimination of leishmaniasis as a public health problem presents significant challenges, given its biological complexity and diversity, physical and clinical manifestations, social and economic impacts, frequently burdensome treatment regimens, and insufficient supply of necessary medicines. However, rigorous prevention and control efforts through strong political commitment and a highly motivated workforce can dramatically reduce its burden. Colombia’s new PDSP, which highlights leishmaniasis control, is an opportunity for a revitalized health system response through committed leadership, intersectoral actions, and partnerships with international organizations that share a common vision.
Endocannabinoid and psychological responses to acute resistance exercise in trained and untrained adults
Authors: Sirotiak Zoe , Gallagher Brandon T. , Smith-Hernandez Courtney A. , Showman Lucas J. , Hillard Cecilia J. , Brellenthin Angelique G. 
Published: December 2023

Introduction
This study examined the effects of acute resistance exercise on circulating endocannabinoid (eCB) and mood responses in trained and untrained healthy adults.

Methods
Thirty-two healthy adults (22.1 ± 2.9 years) were recruited from trained (reporting resistance exercise at least twice per week for ≥ previous three months) and untrained (performing no resistance exercise for ≥ previous three months) groups. Participants (13 male, 19 female) completed three sets of resistance exercise (16 repetitions at 50% 1-repetition max, 12 repetitions at 70% 1-repetition max, 8 repetitions at 80% 1-repetition max). Resistance machines targeted the legs, chest, back, and abdominal muscles. Mood states, affect, and circulating eCB concentrations were evaluated before and after resistance exercise.

Results
There were significant decreases in AEA, PEA, and OEA levels following acute resistance exercise (p <0.05; ds = -0.39, -0.48, -0.65, respectively), with no significant group differences or group by time interactions. 2-AG did not change significantly. Positive affect increased significantly following resistance exercise (p = 0.009), while negative affect decreased (p <0.001). Depressive symptoms, anger, confusion, and total mood disturbance decreased significantly (p <0.05), while vigor increased significantly following resistance exercise (p = 0.005). There were no significant group differences or group by time interactions for any psychological outcomes.

Conclusion
These results indicate that acute resistance exercise may reduce eCB and related lipid concentrations, which is opposite to the increase in lipids typically observed with acute aerobic exercise. Furthermore, psychological improvements occur after resistance exercise regardless of decreases in eCBs, supporting the notion that psychological changes with exercise likely occur through a wide variety of biological and environmental mechanisms.
definición de estándares en la Agricultura 4.0. La Agricultural Industry Electronics Foundation (AEF) e ISOBUS
Authors: Vidosa Regina , Sanz Cerbino Gonzalo , Jelinski Federico 
Published: December 2023

La definición de un estándar común para la interconexión de equipos electrónicos destinados a la producción agrícola constituye un punto nodal en el sendero de convergencia entre la industria de maquinaria agrícola e implementos y las nuevas tecnologías digitales de la Agricultura 4.0. Las estrategias empresariales para la definición de estándares resultan tan importantes como el control, mediante alianzas, adquisiciones y/o fusiones, de las firmas tecnológicas emergentes en las que se desarrollan las nuevas funcionalidades propias de la Agricultura 4.0.
A fin de ampliar nuestro conocimiento sobre la difusión e implementación del estándar ISOBUS y sus implicancias en el sector de la maquinaria agrícola, nos proponemos avanzar en un análisis de los orígenes, el funcionamiento y la composición de la Agricultural Industry Electronics Foundation (AEF). Utilizamos un enfoque metodológico cualitativo, a partir de la revisión de documentación y análisis bibliográfico de fuentes secundarias académicas, periodísticas y empresariales de diferente índole.
La educación sexual integral como política pública con perspectiva de género en la Provincia de La Rioja, 2019-2022
Authors: Estrada María Victoria 
Published: December 2023

El presente trabajo busca dar cuenta de las intervenciones públicas llevadas adelante por el gobierno de la Provincia de La Rioja a partir de la sanción de la Ley de Educación Sexual Integral (ESI) en el año 2006.
Para ello, en primer lugar se realiza una revisión normativa e institucional, respecto de la incorporación de la ESI en la provincia bajo la responsabilidad ejecutiva del Ministerio de Educación de la La Rioja; para luego describir las políticas públicas llevadas adelante en términos educativos y culturales. Finalmente, se reflexionará sobre las resistencias encontradas en el camino y los desafíos a futuro. Es así que se exponen determinadas políticas públicas, como ESIarte o “Chaya es amor por tu pueblo”, las cuales transparentan el vínculo entre la cultura local y su transformación a partir de la ESI.
Si bien este trabajo presenta un abordaje descriptivo, sirve como insumo para entender los avances y resistencias que se plantean en diversas regiones del país, en este caso el noroeste argentino, a la hora de implementar esta ley nacional.
El paradigma del desarrollo sustentable y el dilema del avance científico tecnológico
Authors: Ferrer Esther H. S , Garrido Cordobera Lidia M. R. , Etcheverry Raúl A , Fernández Leonardo F , Piccinino Centeno Garrido Roque , Bermejo Paula N , Etchevers S. Francisco , Vivó Silvana C , Martinez Lima Lucia 
Published: December 2023

El desarrollo sustentable entre sus múltiples implicancias importa que el logro de los avances en materia científica-tecnológica no perjudiquen la vida y el ambiente, tanto en la actualidad como para las generaciones futuras. La problemática que se presenta importa confluir la resolución de dos necesidades que requieren ser igualmente satisfechas: por un lado el necesario avance científico tecnológico y por otro lado, el desarrollo sustentable con especial enfoque en el consumo como derecho humano, centrado en los aspectos preventivos, precautorios y resarcitorios.
En tal sentido, atendemos a las problemáticas que se plantean en torno al consumo sustentable y la afectación que pudiere producirse en algunos casos debido al avance de la ciencia y tecnología, contemplando pues aquí, aspectos de gran relevancia como los que pudieren resultar de los defectos del producto en sentido amplio, y del riesgo del desarrollo en particular.
Estas cuestiones resultan de gran relevancia a fin de proteger efectivamente los derechos de los consumidores y de las generaciones futuras. En tal sentido, nuestra preocupación se compromete en atender aspectos relativos a la faz resarcitoria pero fundamentalmente a la preventiva y precautoria. Para ello, tomamos como caso cuestiones relativas a la industria farmaceútica.