bluuebunny/crossref_metadata_2025_split huggingface dataset:
Precision medicine: Transforming healthcare through personalized treatment and genomic insights
Authors: Mittal Neeti , Bhagat Tripta , Bhagat Rohit , Gulati Gunjan 
Published: January 2024

ABSTRACT
This article explores the paradigm shift brought about by precision medicine in healthcare. It provides an overview of the field’s historical background, key milestones, advantages, real-life examples, major companies, products, challenges, and future prospects. Readers can expect to gain insights into the emergence of precision medicine, its impact on diagnosis and treatment, and its potential to revolutionize healthcare. The article highlights significant achievements such as the completion of the Human Genome Project, the development of targeted therapies, and the role of precision medicine in cancer, cardiovascular disease, rare diseases, infectious diseases, and mental health disorders. It also discusses prominent companies and their contributions to precision medicine. However, challenges such as the cost of genetic testing and the need for robust data infrastructure are explored. The importance of collaboration, education, awareness, regulation, and standardization is emphasized. By the end, readers will have a comprehensive understanding of precision medicine’s promise, its current state, and the steps needed for its widespread adoption, enabling them to grasp its potential impact on patient outcomes and health-care systems.
Navigating psychological and neurobiological etiology with treatment advances of autism-spectrum disorder
Authors: Nandita  , Bhatti Sachinpal , Kumar Saksham , Raj Nishchita , Saran Brijesh 
Published: January 2024

ABSTRACT

Background:
Autism spectrum disorder (ASD) is a complicated neurodevelopmental illness that affects social interaction, communication, and behaviour. It is characterised by a wide range of symptoms and difficulties.

Methods:
Various articles searched from Pubmed central and other search engines for articles related to therapeutic intervention.

Results:
Intense study and clinical attention have been focused on figuring out the causes of autism and the best treatment plans.

Conclusion:
The present level of knowledge about the psychological and neurological aspects influencing the onset of autism, as well as the cutting-edge strategies and therapeutic interventions available for people on the spectrum, are thoroughly reviewed in this article
Diabetes mellitus type II with depression in geriatric population
Authors: Nandita  , Kumar Saksham , Bhatti Sachinpal , Raj Nishchita , Saran Brijesh 
Published: January 2024

ABSTRACT

Background:
Several facets of daily life are impacted by mental health, including how you handle stress, think and feel, interact with people, and make decisions. It makes sense that having a mental health issue could make it more difficult to follow your diabetes treatment plan. Diabetes complications and untreated mental health concerns can both exacerbate each other’s effects. Depression is a medical condition that results in depressed feelings and frequently a loss of interest in previously enjoyed activities. It may interfere with your ability to manage your diabetes and perform effectively at work and at home. Your chance of developing diabetic complications including heart disease and nerve damage increases when you are unable to effectively manage your blood sugar levels. The daily routine traffic jams, family obligations, and daily diabetes care are all sources of stress.

Methods:
Articles searched from Pubmed central and other search engines for articles related to psychological therapeutic intervention.

Results:
Stress can manifest as an emotion, such as fear or rage, as a physical response, such as perspiration or a racing heart, or both. Blood sugar levels can be impacted as well because stress hormones cause blood sugar to fluctuate erratically and because stress from illness or injury can cause blood sugar to rise. Long-term stress might cause other health issues or exacerbate existing ones. The mind and body respond to stress by feeling anxious, which can include anxiety, fear, or tenseness. Anxiety is 20% more common among diabetics than among non-diabetics at some time in their lives.

Conclusion:
These overwhelming emotions, sometimes referred to as diabetes distress, might make you develop bad habits, stop monitoring your blood sugar, and even forget about scheduled doctor’s appointments. The majority of persons with diabetes experience it, frequently following years of effective control.
Stress and Coping among Parents of Preterm Infants Admitted to Neonatal Care |Units of Central Hospitals of Nepal
Authors: Shrestha Tumla , Pandey Bista Archana , Subedi Madhusudan 
Published: January 2024

Background: Hospitalization in neonatal care units (NCUs) is distressing to parents. Stress and inadequate coping with the situation hinder parents' emotional health and parenting roles. The dearth of information is available about it in Nepali context. Therefore, this study was conducted to explore the stress and coping strategies of parents of PTIs in NCUs.
Methods: The descriptive phenomenological study was conducted in NCUs of three public tertiary hospitals in Kathmandu Nepal. In-person in-depth interviews were conducted among the purposively selected 15 parents of preterm and low birth weight infants admitted to NCUs. The obtained data were analyzed using the content analysis method.
Findings: Two themes emerged namely psychological distress and insecurity and coping with the support system. Their distress was related to the condition and progress of their PTIs, infant-parent separation, altered parenting roles, and the burden of longer hospitalization. Family, friends, other parents, and staff of NCUs were their support sources. They coped with the situation with religious faith, patience, sharing with peer parents, being close with the PTIs, and involving in PTI care.
Conclusion: Admission of PTIs to NCUs is distressing to parents. In addition, to support from family and friends, parents valued NCU staffs' support for coping and expected more support. Opportunities for infant-parent attachment, care involvement and peer-to-peer support are their effective coping measures. Improving parental support provision in NCUs considering the stressors and effective coping measures would be praiseworthy to enhance the psychological well-being of the parents
Decision-making: The Process Contributing to Professional Public Administration
Authors: Altunyan Katerina 
Published: January 2024

This article analysis one of the main issues of public administration theory and practice, which is helpful in government functioning and policy-making. Research study includes the discourse on how to plan and make decisions on behalf of democratic attitude. Public administration is utmost outcome, and the success or failure of the government depends on it. Theoretical debate on decision-making process, accordingly, surveys the fundamental perception on rational and incremental decision-making processes. It refers basically to the administrative institutions. Decision making is important for organizational effectiveness because of its central role in the overall process of directing and controlling. Decisions do not automatically guarantee all programmed outcomes, but denoting actions with professionalism and public support. As a valuable process it is likely to be a central element of management and leadership. Comparative study of examples of developed democratic systems shows the high responsibility of public institutes and government as key actors. Particular attention is paid there to the professionalism of government, which is a vital characteristic of any democratic public administration and virtually a policy quality. Findings of current research shows that decisions are not based solely on laws and regulations. Moreover, as the study shows, many other appropriate skills of decision-makers are important that will be seen with the close linkages with strategic governance.
Teachers’ Knowledge and Usage of Ethnomathematics in Asokwa Municipality (Kumasi) of Ashanti Region of Ghana
Authors: Osei Seth Kwame , Bonyah Ebenezer , Arthur Yarhands D 
Published: January 2024

This study investigated teachers’ knowledge and usage of ethnomathematics in Asokwa Municipality (Kumasi) in the Ashanti region of Ghana. The triangulation design of the mixed method was used. Purposive sampling was used to select all the 62 mathematics teachers from all the public junior high schools in the municipality. Results from the data analysis showed that mathematics teachers in Asokwa Municipality possess a high level of knowledge of ethnomathematics, with an overall mean score of 3.68 and a standard deviation of 0.61. The study recommended that Ghana Tertiary Education Commission (GTEC) should ensure that teachers’ colleges of education train mathematics teachers on the integration of ethnomathematics in the teaching of mathematics
The Use of Deixis in Students’ Writing of Descriptive Texts
Authors: Indriastuti Mutia Olivia , Pulungan Anni Holila , Natsir Muhammad 
Published: January 2024

This study aims to identify the types of deixis, and the deixis used, and to analyze the reason deixis used in the students’ writing descriptive text at the tenth grade MIA 2 high school Kemala Bhayangkari Medan. This research used descriptive qualitative research where the participants were 20 students who took English class. The result of this research showed five types of deixis, how the deixis are used, and the reason deixis is used in their writing using Levinson's theory (1983). Five types of deixis are spatial deixis, temporal deixis, person deixis, social deixis, and discourse deixis. From 20 total data, the researcher found 186 deictic words in the students’ writing. 84 or 45% in the spatial deixis, 40 or 22% in the person deixis, 25 or 13% in the temporal deixis, 22 or 12% in the discourse deixis, and 15 or 8% in the social deixis. Therefore, the reasons students used deixis are: to Indicate a specific location, chronology of events, to convey a personal point of view, to incorporate cultural and social signifiers, and to create a strong and coherent connection.
PENGARUH PARTISIPASI PENYUSUNAN ANGGARAN TERHADAP KINERJA MANAJERIAL PADA PT JASA MARGA (PERSERO) Tbk CABANG PURBALEUNYI BANDUNG
Authors: ELISABETH CHRISTINE , Suwarsa Toto 
Published: January 2024

PT Jasa Marga merupakan perusahaan infrastruktur yang bergerak dibidang pelayanan jasa dan penyediaan jalan tol. Agar pelayanan jasa berjalan dengan baik maka dibutuhkan suatu manajemen yang harus dilaksanakan sesuai dengan komitmen pencapaian tujuan. Penelitian ini bertujuan untuk mengetahui bagaimana partisipasi penyusunan anggaran, kinerja manajerial dan adakah pengaruh antara partisipasi penyusunan anggaran terhadap kinerja manajerial di PT Jasa Marga (Persero) Tbk Cabang Purbaleunyi Bandung.
Pada penelitian ini metode yang digunakan adalah metode uji validitas, uji reliabilitas, regresi linear sederhana, korelasi spearman rank, koefisien determinasi dan pengujian hipotesis yaitu uji t.
Adapun regresi linear sederhana dengan nilai yang diperoleh sebesar Y=9,960+0,761X. Untuk analisis determinasi (Kd) menunjukkan angka sebesar 0,858, uji t menunjukkan thitung > ttabel (5,925 > 2,101) berarti bahwa thitung untuk variabel partisipasi penyusunan anggaran berada di daerah penolakan HO atau daerah penerimaan Ha. Berdasarkan penelitian dilakukan dapat disimpulkan bahwa pengaruh partisipasi penyusunan anggaran memiliki hubungan yang kuat terhadap kinerja manajerial.
PENGARUH PAJAK HOTEL, PAJAK RESTORAN, DAN PAJAK HIBURAN TERHADAP PENDAPATAN ASLI DAERAH KABUPATEN GARUT
Authors: Latipatul Hamdah Dida Farida , Wahyuni Resa Sri 
Published: January 2024

This research aims to explore the impact of hotel, restaurant and entertainment taxes on original regional income of Garut Regency during the 2015-2022 period. The data for this research is sourced from the implementation reports hotel, restaurant and entertainment tax submitted by the Garut Regency Regional Revenue Agency.
The research adopts a quantitative approach, employing data collection methods such as interviews and documents analysis, while data analysis techniques applied in this study include multiple linear regression analysis, coefficient of determination and hypothesis testing using the F test and t test. Data processing in this study was carried out using the SPSS version 26 for Windows program.
The findings of this research reveal that collectively hotel, restaurant and entertainment taxes significantly impact local revenue. However, when examined hotel and entertainment taxes do not have a significant impact on local revenue while restaurant taxes have a significant impact on local revenue.
International Effect: The Ongoing Tension with Medical Marijuana Legalization
Authors: Vadasz Gabriel 
Published: January 2024

Purpose: In the landscape of the United States, an escalating number of states are ushering in a new era by enacting legislation that affords individuals the right to employ cannabis for medical purposes. However, this commendable stride toward medical autonomy is accompanied by an escalating tension, a discordant symphony of conflict between state and federal jurisdictions. This study embarks on a journey through the labyrinth of legislative intricacies, seeking to unravel the roots of this tension and proffering insights into potential resolutions. At the heart of the matter lies the dichotomy between state and federal legislation. While states pave the way for medical cannabis use, the federal stance casts a looming shadow of ambiguity and discord. The conflict, multifaceted and dynamic, beckons for a nuanced exploration.
Methodology: The study adopted desktop literature research design.
Findings: By delving into the intricacies of the legislative measures themselves, this research identifies mitigating factors that can potentially alleviate the tension between conflicting jurisdictions. Mitigation, however, requires more than a superficial understanding of legislative nuances. It demands a comprehensive acknowledgment of the extensive legal and medical data interwoven with the fabric of cannabis use for medical purposes.
Unique Contribution to Theory, Practice and Policy: The study advocates for a holistic approach, urging policymakers to draw upon a repository of knowledge that transcends mere legal frameworks. In doing so, it seeks to bridge the gap between state and federal perspectives, fostering a more informed and cooperative discourse. Navigating the path toward resolution involves a delicate balance. The sculpting of legislative measures should be informed by a deep appreciation of the medical intricacies associated with cannabis use. The study underscores the significance of considering medical data as an essential compass in the journey toward harmonizing state and federal regulations. By acknowledging the complex interplay between legality and medical efficacy, this research contributes to the ongoing dialogue surrounding cannabis legislation. In conclusion, this study illuminates the intricate dance between state and federal jurisdictions in the realm of medical cannabis use. Through a meticulous examination of legislative intricacies and a robust consideration of legal and medical data, it endeavors to pave the way for a more harmonious coexistence between state and federal perspectives.
The Role of Social Capital in Public Health: Implications for Social Health Promotion
Authors: Ndayiragije Francine 
Published: January 2024

This examine investigates the position of social capital in public health and its effect on promoting social health by means of studying the sample's demographic traits from 18-24 to 55, exercising habits, and universal properly-being rankings from 18-24 to 55, in addition to the correlation between hours of exercising and nicely-being rankings Table three unveils the complex relationship between exercise hours and nicely-being rankings, supplying a quantitative perception into how those two variables interconnect throughout all age groups inside the have a look at. The demographic evaluation in Table 1 provides a deeper understanding of the sample populace, guiding the development of fitness promoting strategies focused to specific network wishes. Table 2 highlights the relationship among workout conduct and well-being scores, stressing the capability impact of bodily hobby on an man or woman's properly-being. Correlation evaluation in Table 3 shows a complicated relationship among hours of exercise and well-being, strain and social capital mediation. The implications for social fitness advertising highlight that interventions that intersect with social capital can play an essential function in shaping healthier communities. By leveraging the insights of demographic evaluation and correlations, practitioners and coverage makers can layout interventions that not most effective encourage physical pastime however additionally improve the social surroundings that helps health behaviors. While acknowledging the restrictions of the take a look at, these findings provide a foundation for future studies and proof-based interventions. A holistic method that integrates social capital issues into public fitness initiatives has the capacity to create resilient, connected, and healthier groups.
Translation of Auxiliary Verbs in Novel the Fault in Our Stars
Authors: Yoel Maureen Vanessa , Wibowo Agung Prasetyo 
Published: January 2024

This study intends to: (i) analyze the forms of auxiliary verbs and their translation found in the data source, (ii) analyze the translation strategies used in the translation process from the source language and target language. This research study focuses on English auxiliary verbs and their translations into Indonesian found in the novel entitled “The Fault in Our Stars” and the translation strategies in the translation process. In analyzing the data, the analysis uses the translation strategies proposed by (Chesterman, 2016). The method that the researcher employs is namely qualitative method, while the approach is descriptive qualitative. The data taken is purposeful sampling. The data taken for each auxiliary verbs are 50 data. This research shows that most of the English auxiliary verbs are not translated in Indonesian because there is no fixed equivalent for auxiliary verbs in Indonesian. There are only four strategies out of thirty strategies proposed by Chesterman are used. The strategies are literal (7 data), transposition (28 data), unit shift (12 data), and compression (28 data). Moreover, the dominant strategy used are transposition and compression, for each of them is 28 data. Thus, it can be implied that only 2 of 30 translation strategies that mostly used in translating auxiliary verbs.
HUBUNGAN INDEKS MASSA TUBUH DENGAN KADAR KOLESTEROL PADA LANSIA DI WILAYAH KERJA PUSKESMAS KOTA BATAM
Authors: Erda Roza , Yunaspi Didi , Nuraisyah Siti , Devi Putri Yulia 
Published: January 2024

High cholesterol levels (hypercholesterolemia) is a very serious problem because it is one of the most important risk factors for heart disease and hypertension. Abnormalities found in increasing total cholesterol levels. The purpose of this study was to assess the relationship between body mass index and cholesterol levels in the elderly at Health Center, Batam City. This study used Observational Analitic method of cross-sectional approach. The ampling technique used simple random sampling of 65 respondents. This research was conducted in the work area of the Health Center, Batam City in 2022. the tools used to measure Body Mass Index (BMI) with digital scales with an accuracy of 0.1 kg. measuring height is a stature meter with a length range of 0-200 cm, measuring cholesterol levels with Cholesterol Meter. Univariate analysis in this study consists of independent variables, namely BMI (body mass index) and the dependent variable, namely Total Cholesterol Levels in the elderly, while bivariate analysis uses the chi-square test (x²). There is a significant relationship between the relationship between body mass index and cholesterol levels in the elderly in the Health Center Working Area, Batam City in 2022, with the results; statistical tests obtained a p-value of 0.000 (p-value <0.05). For Health Services It is expected to provide counseling to the elderly to better assist and help to realize health
Ecosystem Services and Urban Planning
Authors: Sangha Savun 
Published: January 2024

Purpose: The main objective of the study was to explore ecosystem services and urban planning.
Methodology: The study adopted a desktop research methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library.
Findings: The findings revealed that there exists a contextual and methodological gap relating to ecosystem services and urban planning. Preliminary empirical review emphasized the need for sustainable urban planning practices that integrate ecological considerations, prioritize green infrastructure and biodiversity conservation, and address disparities in access to ecosystem services. Urban planners and policymakers are key actors in ensuring the well-being of urban populations and the environment, making informed decisions about land use, transportation, and sustainability practices crucial. These findings have implications for environmental advocacy groups and policymakers, as they underscore the importance of advocating for eco-friendly urban development to protect and enhance critical ecosystem services, ultimately creating more resilient and equitable cities that benefit both people and the environment.
Unique Contribution to Theory, Practice and Policy: The Urban Political Ecology Theory (UPE), Ecological Modernization Theory and Resilience theory may be used to anchor future studies on ecosystem services. The study provided recommendations to enhance urban planning practices. It suggests integrating ecosystem services into planning processes, emphasizing the importance of green infrastructure and biodiversity conservation within cities, and promoting community engagement and collaboration among stakeholders. These recommendations aim to create more resilient and sustainable urban environments that prioritize the well-being of residents while safeguarding and enhancing the valuable ecosystem services urban areas provide.