bluuebunny/crossref_metadata_2025_split huggingface dataset:
A modern Sr/Ca‐δ18O‐sea surface temperature calibration for Isopora corals on the Great Barrier Reef
Authors: Brenner Logan D. , Linsley Braddock K. , Potts Donald C. 
Published: February 2017

AbstractIsopora (Acroporidae) is a genus of often encrusting, branching to submassive corals that are common in many shallow habitats on modern and fossil Indo‐West Pacific reefs. Although abundant, Isopora is largely absent from paleoceanographic literature. The scarcity of large Porites and the abundance of Isopora retrieved from the Great Barrier Reef (GBR) on Integrated Ocean Drilling Program Expedition 325 focused paleoceanographic attention on Isopora. Here we provide the first independent high‐resolution calibration of both Sr/Ca and δ18O for temperature analyses based on Isopora and demonstrate its consistency with Porites records. We developed modern skeletal Sr/Ca‐ and δ18O‐sea surface temperature (SST) calibrations based on five modern Isopora colonies from Heron Island in the southern GBR. Pairing the coral Sr/Ca record with monthly SST data yielded Sr/Ca‐SST sensitivities from −0.061 ± 0.004 (centered) to −0.083 ± 0.007 (raw) mmol/mol °C−1 based on reduced major axis regressions. These sensitivities are in the middle of the range of published Porites values and overlap most published values for Isopora, −0.075 ± 0.011 to −0.065 ± 0.011 mmol/mol °C−1. The δ18O‐SST sensitivities range from −0.184 ± 0.014 (centered) to −0.185 ± 0.014 (raw) ‰ °C−1, assuming that all seasonal variation in δ18O was due to SST. These δ18O‐SST sensitivities are smaller than the widely accepted value of −0.23‰ °C−1 for biogenic aragonite but are at the upper end of high‐resolution Porites‐defined sensitivities that are consistently less than the aforementioned established value. Our results validate the use of Isopora as an alternative source of paleoceanographic records in habitats where large massive Porites are scarce or absent.
A new record of Atlantic sea surface salinity from 1896 to 2013 reveals the signatures of climate variability and long‐term trends
Authors: Friedman Andrew R. , Reverdin Gilles , Khodri Myriam , Gastineau Guillaume 
Published: February 2017

AbstractSea surface salinity (SSS) is a major ocean circulation component and indicator of the hydrological cycle. Here we investigate an unprecedented Atlantic SSS compilation from 1896 to 2013 and analyze the main modes of SSS decadal variability. Using principal component analysis, we find that the low‐latitude (tropical and subtropical) Atlantic and the subpolar Atlantic have distinct variability. Subpolar and low‐latitude SSS are negatively correlated, with subpolar anomalies leading low‐latitude anomalies by about a decade. Subpolar SSS varies in phase with the Atlantic Multidecadal Oscillation (AMO), whereas low‐latitude SSS varies in phase with the North Atlantic Oscillation (NAO). Additionally, northern tropical SSS is anticorrelated with Sahel rainfall, suggesting that SSS reflects the Intertropical Convergence Zone latitude. The 1896–2013 SSS trend shows amplification of the mean SSS field, with subpolar freshening and low‐latitude salinification. The AMO and NAO have little effect on the long‐term trend but contribute to the trend since 1970.
Synthesis of Fluorenes with an All‐Carbon Quaternary Center via Palladium‐Catalyzed Dual Arylation using Cyclic Diaryliodonium Triflates
Authors: Peng Xiaopeng , Luo Hongwen , Wu Fuhai , Zhu Daqian , Ganesan A. , Huang Peng , Wen Shijun 
Published: February 2017

AbstractCatalyzed by palladium species, cyclic diaryliodonium salts underwent dual C‐aryl functionalization smoothly with activated methylene sources. With this new finding, a series of diversified fluorenes with an all‐carbon quaternary center was quickly constructed. Moreover, our approach also provided various novel spirofluorenes containing barburate acid or indane motifs which are featured in medicinal drugs and functional materials.magnified image
Synthesis of 2‐Substituted Quinolines via Rhodium(III)‐Catalyzed C–H Activation of Imidamides and Coupling with Cyclopropanols
Authors: Zhou Xukai , Qi Zisong , Yu Songjie , Kong Lingheng , Li Yang , Tian Wan‐Fa , Li Xingwei 
Published: February 2017

AbstractAn efficient synthesis of 2‐substituted quinolines from readily available cyclopropanols and imidamides has been developed, where the cyclopropanol acts as a C3 synthon. With the assistance of a bifunctional imidamide directing group, the reaction occurred via sequential C–H/C–C cleavage and C–C/C–N bond formation.magnified image
One‐particle density matrix characterization of many‐body localization
Authors: Bera Soumya , Martynec Thomas , Schomerus Henning , Heidrich‐Meisner Fabian , Bardarson Jens H. 
Published: February 2017

We study interacting fermions in one dimension subject to random, uncorrelated onsite disorder, a paradigmatic model of many‐body localization (MBL). This model realizes an interaction‐driven quantum phase transition between an ergodic and a many‐body localized phase, with the transition occurring in the many‐body eigenstates. We propose a single‐particle framework to characterize these phases by the eigenstates (the natural orbitals) and the eigenvalues (the occupation spectrum) of the one‐particle density matrix (OPDM) in individual many‐body eigenstates. As a main result, we find that the natural orbitals are localized in the MBL phase, but delocalized in the ergodic phase. This qualitative change in these single‐particle states is a many‐body effect, since without interactions the single‐particle energy eigenstates are all localized. The occupation spectrum in the ergodic phase is thermal in agreement with the eigenstate thermalization hypothesis, while in the MBL phase the occupations preserve a discontinuity at an emergent Fermi edge. This suggests that the MBL eigenstates are weakly dressed Slater determinants, with the eigenstates of the underlying Anderson problem as reference states. We discuss the statistical properties of the natural orbitals and of the occupation spectrum in the two phases and as the transition is approached. Our results are consistent with the existing picture of emergent integrability and localized integrals of motion, or quasiparticles, in the MBL phase. We emphasize the close analogy of the MBL phase to a zero‐temperature Fermi liquid: in the studied model, the MBL phase is adiabatically connected to the Anderson insulator and the occupation‐spectrum discontinuity directly indicates the presence of quasiparticles localized in real space. Finally, we show that the same picture emerges for interacting fermions in the presence of an experimentally‐relevant bichromatic lattice and thereby demonstrate that our findings are not limited to a specific model.
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Total Synthesis of the Cytotoxic Marine Triterpenoid Isodehydrothyrsiferol Reveals Partial Enantiodivergency in the Thyrsiferol Family of Natural Products
Authors: Hoshino Akihiro , Nakai Haruka , Morino Miyako , Nishikawa Keisuke , Kodama Takeshi , Nishikibe Kento , Morimoto Yoshiki 
Published: February 2017

AbstractRecently, the phenomenon of enantiodivergence was uncovered as a new phenomenon in the biosynthesis of natural products. In nature, chiral natural products are usually produced in optically active form, but both enantiomers sometimes arise in different genera and/or species or in a single species. Here we show through enantioselective total synthesis that the natural product isodehydrothyrsiferol shows partial enantiodivergency in that six of the nine or ten asymmetric centers are enantiomeric to those of other members of the marine squalene‐derived triterpenoid thyrsiferol family. In addition, isodehydrothyrsiferol and dehydrothyrsiferol, which show partial enantiodivergency, were isolated from the same producer, the red alga Laurencia viridis. These results demonstrate that partial enantiodivergence can develop even between natural products originating from a single species.
C,O‐Chelated BINOL/Gold(III) Complexes: Synthesis and Catalysis with Tunable Product Profiles
Authors: Cui Jian‐Fang , Ko Hok‐Ming , Shing Ka‐Pan , Deng Jie‐Ren , Lai Nathanael Chun‐Him , Wong Man‐Kin 
Published: February 2017

AbstractUnprecedented stable BINOL/gold(III) complexes, adopting a novel C,O‐chelation mode, were synthesized by a modular approach through combination of 1,1′‐binaphthalene‐2,2′‐diols (BINOLs) and cyclometalated gold(III) dichloride complexes [(C^N)AuCl2]. X‐ray crystallographic analysis revealed that the bidentate BINOL ligands tautomerized and bonded to the AuIII atom through C,O‐chelation to form a five‐membered ring instead of the conventional O,O′‐chelation giving a seven‐membered ring. These gold(III) complexes catalyzed acetalization/cycloisomerization and carboalkoxylation of ortho‐alkynylbenzaldehydes with trialkyl orthoformates.
Syntheses, characterization, antibacterial activity and molecular modelling of phenylantimony(III) heteroleptic derivatives containing substituted oximes and piperidine dithiocarbamate
Authors: Beniwal Savita , Chhimpa Sunil , Gaur Deepti , John P.J. , Singh Yashpal , Sharma Jyoti 
Published: February 2017

Six new heteroleptic phenylantimony(III) derivatives containing substituted oximes and dithiocarbamate moieties of the type (where R = ─C6H5, X = ─CH3 (2a); R = ─C6H4CH3, X = ─CH3 (2b); R = ─C6H4Cl, X = ─CH3 (2c); R = ─C6H4Br, X = ─CH3 (2d); R = ─C6H4OH, X = ─H (2e); R(X)C = (2f)) have been synthesized by the reactions of phenylantimony(III) dichloride with the sodium salt of substituted oximes and dithiocarbamate moiety in unimolar ratio with stirring in dichloromethane. All these newly synthesized derivatives have been characterized using physicochemical and elemental analyses. Structures have been proposed on the basis of infrared, 1H NMR, 13C NMR and LC–MS spectral studies and molecular modelling. In these derivatives the oxime behaves in an unidentate manner whereas dithiocarbamate behaves in a monofunctional anisobidentate manner. Pseudo‐trigonal bipyramidal (ψ‐TBP) geometry around the antimony metal centre is proposed for these phenylantimony(III) heteroleptic derivatives. The geometry of a representative complex has been optimized through molecular modelling. These newly synthesized derivatives were screened against Bacillus subtilis (Gram‐positive) and Escherichia coli (Gram‐negative) bacteria to evaluate their antibacterial potential. The structure–activity relationship for antibacterial activity among the four derivatives 2a, 2c, 2e and 2f is discussed.
Eco‐friendly synthesis of 3,4‐dihydroquinoxalin‐2‐amine, diazepine‐tetrazole and benzodiazepine‐2‐carboxamide derivatives with the aid of MCM‐48/H5PW10V2O40
Authors: Vessally Esmail , Hosseinzadeh‐Khanmiri Rahim , Ghorbani‐Kalhor Ebrahim , Es'haghi Moosa , Ejlali Ladan 
Published: February 2017

A heterogeneous material composed of MCM‐48/H5PW10V2O40 was produced and used as an efficient, eco‐friendly and highly recyclable catalyst for the one‐pot and multicomponent synthesis of 3,4‐dihydroquinoxalin‐2‐amine, diazepine‐tetrazole and benzodiazepine‐2‐carboxamide derivatives in aqueous media and at room temperature with high yields in short reaction times (40–60 min). The recoverable catalyst was easily recycled at least five times without any loss of catalytic activity. The structures of obtained products were confirmed using 1H NMR and 13C NMR spectra.
Ethaline and Glyceline binary eutectic mixtures: characteristics and intermolecular interactions
Authors: Mjalli F.S. , Ahmed O.U. 
Published: February 2017

AbstractDeep eutectic solvents (DESs) are ionic liquids analogs that have been the subject of a growing interest in the scientific community. Governed by their favorable chemical and physical properties, they were utilized in a wide variety of fields. DESs possessing both desirable and undesirable properties for a specific application are not uncommon. As such, investigation into the variation of their properties upon mixing, in order to understand and improve their properties for a specific application, seems promising. In this study, the measurement of the physical and selected excess thermodynamic properties of Ethaline upon addition of Glyceline was carried out. The deviation of excess molar volume as a function of Glyceline molar fraction was observed to be alternating between negative and positive. This implies that the predominant interactions is due to either the difference in the sizes and shapes of the constituent molecules or to the effect dispersion forces. The highest deviations of the excess molar volume were observed at 30 and 90 mol% Glyceline. Density, viscosity, pH, RI and conductivity of the pure and DES mixtures were measured at different Glyceline molar fractions within the temperature range of 20 to 80 °C. © 2017 Curtin University of Technology and John Wiley & Sons, Ltd.
Efficient Color‐Tunable Copper(I) Complexes and Their Applications in Solution‐Processed Organic Light‐Emitting Diodes
Authors: So Gary Kwok‐Ming , Cheng Gang , Wang Jian , Chang Xiaoyong , Kwok Chi‐Chung , Zhang Hongxing , Che Chi‐Ming 
Published: February 2017

AbstractA series of dppnc‐ and neocuproine‐based CuI complexes (dppnc=7,8‐bis(diphenylphosphino)‐7,8‐dicarba‐nido‐undecaborate) are synthesized and the emission color of these CuI complexes can be tuned from green to deep red via rational modification of the neocuproine ligand structure. The molecular structures of the emissive CuI complexes, Cu(dppnc)‐G (green emitting), Cu(dppnc)‐Y (yellow emitting), and Cu(dppnc)‐R (red emitting), are characterized and their electronic structures and related transition properties are elucidated by photo‐physical and computational (density functional theory) studies. The calculation results suggest that thermally activated delayed fluorescence (TADF) is the emission mechanism for these CuI complexes. Efficient solution‐processed green‐, yellow‐, and red‐emitting OLEDs are fabricated based on the emissive complexes as the dopants. High external quantum efficiency (EQE) of 15.20 % and current efficiency of 48.15 cd A−1 at 1000 cd m−2 are achieved in the green‐emitting device with Cu(dppnc)‐G. A maximum EQE of 10.17 %, CIE coordinates of (0.61, 0.38) and a maximum electroluminescent peak of 631 nm are achieved in the red device based on Cu(dppnc)‐R.
Semi‐Global Exquisite Disturbance Attenuation Control for Perturbed Uncertain Nonlinear Systems
Authors: Yang Jun , Zhang Chuanlin , Li Shihua , Niu Xitong 
Published: February 2017

AbstractMotivated by the design of disturbance observers with active elimination of the adverse effects caused by system uncertainties and disturbances, the problem of semi‐global exquisite disturbance attenuation control for a class of perturbed nonlinear systems is investigated in this paper. A feedback domination technique is utilized to integrate with the disturbance observer design and then a general composite active anti‐disturbance control law is proposed. With a recursive design procedure, the mismatched lumped disturbances are compensated in a novel step‐by‐step way while the non‐vanishing nonlinearities are treated via a feedback domination approach, rather than utilizing the straightforward feedback linearization method. The closed‐loop control performance and disturbance rejection ability now can be improved. A rigorous stability analysis assures the effectiveness of the proposed strategy. Numerical simulation results affirm the improved control and disturbance rejection performances with respect to several related existing results.
Short‐term highway traffic flow prediction based on a hybrid strategy considering temporal–spatial information
Authors: Li Linchao , He Shanglu , Zhang Jian , Ran Bin 
Published: February 2017

SummaryShort‐term traffic flow prediction is fundamental for the intelligent transportation system and is proved to be a challenge. This paper proposed a hybrid strategy that is general and can make use of a large number of underlying machine learning or time‐series prediction models to capture the complex patterns beneath the traffic flow. With the strategy, four different combinations were implemented. To consider the spatial features of traffic phenomenon, several different state vectors including different observations were built. The performance of the proposed strategy was investigated using the traffic flow measurements from the Traffic Operation and Safety Laboratory in Wisconsin, USA. The results show the overall performance of hybrid strategy is better than a single model. Also, incorporating observations from adjacent junctions can improve prediction accuracy. Copyright © 2017 John Wiley & Sons, Ltd.
Neubau einer integralen Spannbetonbrücke
Authors: Fuchs Maximilian , Blank Gregor , Schneider Andreas , Paukner Florian 
Published: February 2017

AbstractDer Neubau des Überführungsbauwerks BW 03 über die B20 im Zuge des dreistreifigen Ausbaus der Bundesstraße im Abschnitt Burghausen – Marktl am Inn stellte eine spannende Ingenieuraufgabe dar. Der gestalterische Anspruch und die vielfältigen Anforderungen aus Nutzung und Trassierung der sich kreuzenden Verkehrswege erforderten eine unkonventionelle Entwurfslösung. Der Beitrag beschreibt den Entwurf, die Konstruktion und die Ausführung der aufgelösten Rahmenbrücke als integrale Spannbetonkonstruktion.
Messtechnische Dauerüberwachung zur Absicherung der Restnutzungsdauer eines spannungsrisskorrosionsgefährdeten Brückenbauwerks
Authors: Bolle Guido , Mertzsch Olaf , Marx Steffen 
Published: February 2017

AbstractAusgangspunkt für die Dauerüberwachung der Brücke über die Bahn in Waren (Müritz) bilden die Ergebnisse der Nachrechnung und der Spannstahluntersuchungen. Entsprechend diesen war davon auszugehen, dass das Bauwerk zwar spannungsrisskorrosionsgefährdeten Spannstahl enthält, jedoch eine ausreichende Ankündigung bezüglich eines duktilen Versagens besitzt. Damit ist der Weiterbetrieb der Brücke unter Voraussetzung eines verkürzten Inspektionsintervalls möglich. Wegen der stark eingeschränkten Inspizierbarkeit des Bauwerks im laufenden Betrieb wurde die erforderliche zeitlich engmaschige visuelle Begutachtung durch ein Bauwerksmonitoring ersetzt. Im Fokus stand dabei nicht die ganzheitliche messtechnische Observation des Bauwerks, sondern die zielgerichtete und wirtschaftliche Registrierung einer eventuell auftretenden Biegerissbildung.Innerhalb des bisher zweijährigen Messzeitraums wurde das Auftreten eines Biegerisses unter Gebrauchslasten und damit das tatsächliche Eintreten des Riss‐vor‐Bruch‐Kriteriums detektiert. Der Beitrag zeigt die prinzipielle Vorgehensweise beim zielgerichteten Sammeln von Informationen als Grundlage für eine sichere Entscheidungsfindung sowie bei der Planung, Ausführung und Bewertung der Dauermessungen und deren Einordnung in den Begutachtungsprozess des Bauwerks.
ATF6β‐based fine‐tuning of the unfolded protein response enhances therapeutic antibody productivity of Chinese hamster ovary cells
Authors: Pieper Lisa A. , Strotbek Michaela , Wenger Till , Olayioye Monilola A. , Hausser Angelika 
Published: February 2017

ABSTRACTThe dynamics of protein folding and secretion are key issues in improving the productivity and robustness of Chinese hamster ovary (CHO) producer cells. High recombinant protein secretion in CHO producer clones triggers the activation of the unfolded protein response (UPR), an intracellular response to the accumulation of unfolded and misfolded proteins in the endoplasmic reticulum (ER). We previously reported that the human microRNA (miRNA) miR‐1287 enhances productivity in IgG‐expressing CHO cells (CHO‐IgG). Here, through next‐generation sequencing (NGS), we identified the activating transcription factor 6 beta (ATF6β), a repressor of the pro‐survival and UPR promoting factor ATF6α, as a direct target gene of miR‐1287 in CHO‐IgG cells. We show that the transient depletion of ATF6β resulted in enhanced specific productivity comparable to that of miR‐1287‐expressing CHO‐IgG cells. Strikingly, stable  ATF6β knockdown in CHO‐IgG cells significantly improved antibody titer and viable cell density under fed‐batch conditions. This was associated with the elevated expression of the UPR genes glucose‐regulated protein 78 (GRP78), homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1) and CCAAT/enhancer‐binding protein homologous protein (CHOP). We hence demonstrate that ATF6β‐based cell line engineering is a promising strategy to improve the productivity of CHO producer cells by activating an optimally balanced UPR program. Biotechnol. Bioeng. 2017;114: 1310–1318. © 2017 Wiley Periodicals, Inc.
Simultaneous densitometric determination of anthelmintic drug albendazole and its metabolite albendazole sulfoxide by HPTLC in human plasma and pharmaceutical formulations
Authors: Pandya Jui J. , Sanyal Mallika , Shrivastav Pranav S. 
Published: February 2017

AbstractA new, simple, accurate and precise high‐performance thin‐layer chromatographic method has been developed and validated for simultaneous determination of an anthelmintic drug, albendazole, and its active metabolite albendazole, sulfoxide. Planar chromatographic separation was performed on aluminum‐backed layer of silica gel 60G F254 using a mixture of toluene–acetonitrile–glacial acetic acid (7.0:2.9:0.1, v/v/v) as the mobile phase. For quantitation, the separated spots were scanned densitometrically at 225 nm. The retention factors (Rf) obtained under the established conditions were 0.76 ± 0.01 and 0.50 ± 0.01 and the regression plots were linear (r2 ≥ 0.9997) in the concentration ranges 50–350 and 100–700 ng/band for albendazole and albendazole sulfoxide, respectively. The method was validated for linearity, specificity, accuracy (recovery) and precision, repeatability, stability and robustness. The limit of detection and limit of quantitation found were 9.84 and 29.81 ng/band for albendazole and 21.60 and 65.45 ng/band for albendazole sulfoxide, respectively. For plasma samples, solid‐phase extraction of analytes yielded mean extraction recoveries of 87.59 and 87.13% for albendazole and albendazole sulfoxide, respectively. The method was successfully applied for the analysis of albendazole in pharmaceutical formulations with accuracy ≥99.32%.
Structural Changes of Binary/Ternary Spinel Oxides During Ethanol Anaerobic Decomposition
Authors: Vozniuk Olena , Bazzo Cristian , Albonetti Stefania , Tanchoux Nathalie , Bosselet Françoise , Millet Jean‐Marc M. , Di Renzo Francesco , Cavani Fabrizio 
Published: February 2017

AbstractSeveral M‐modified iron oxides of the spinel family have proven to be effective electron and O2− vectors for the production of hydrogen in the chemical‐loop reforming of bio‐alcohols. The present work is specifically focused on investigation of ethanol anaerobic decomposition over spinel oxides, which results in significant structural changes of the oxygen carrier material itself and corresponds to a first step of the chemical‐loop reforming process. In particular, a series of binary/ternary M‐modified ferrospinels were prepared by a co‐precipitation method and tested in terms of both redox properties and intrinsic catalytic activity in addition to a complex ex situ study that encompasses the solid‐state chemistry investigations of the fresh and reduced oxygen carrier materials. It was found that Co/Cu incorporation facilitates total/partial oxidation of ethanol, giving rise to high yields of H2, COx, and H2O; whereas Mn incorporation predominantly favored dehydrogenation and condensation reactions, leading to the formation of acetaldehyde and acetone. In addition, the incorporation of Mn contributed to significantly reduce the amount of coke formed; however, it caused a lower intrinsic reducibility, which was explained by the formation of a thermodynamically stable and hardly reducible layer of MnxFeyO solid solution.