bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid detoxification via glutathione S‐transferase (GST) conjugation confers a high level of atrazine resistance in Palmer amaranth (Amaranthus palmeri)
Authors: Nakka Sridevi , Godar Amar S , Thompson Curtis R , Peterson Dallas E , Jugulam Mithila 
Published: May 2017

AbstractBACKGROUNDPalmer amaranth (Amaranthus palmeri) is an economically troublesome, aggressive and damaging weed that has evolved resistance to six herbicide modes of action including photosystem II (PS II) inhibitors such as atrazine. The objective of this study was to investigate the mechanism and inheritance of atrazine resistance in Palmer amaranth.RESULTSA population of Palmer amaranth from Kansas (KSR) had a high level (160 − 198‐fold more; SE ±21 − 26) of resistance to atrazine compared to the two known susceptible populations MSS and KSS, from Mississippi and Kansas, respectively. Sequence analysis of the chloroplastic psbA gene did not reveal any known mutations conferring resistance to PS II inhibitors, including the most common Ser264Gly substitution for triazine resistance. However, the KSR plants rapidly conjugated atrazine at least 24 times faster than MSS via glutathione S‐transferase (GST) activity. Furthermore, genetic analyses of progeny generated from reciprocal crosses of KSR and MSS demonstrate that atrazine resistance in Palmer amaranth is a nuclear trait.CONCLUSIONAlthough triazine resistance in Palmer amaranth was reported more than 20 years ago in the USA, this is the first report elucidating the underlying mechanism of resistance to atrazine. The non‐target‐site based metabolic resistance to atrazine mediated by GST activity may predispose the Palmer amaranth populations to have resistance to other herbicide families, and the nuclear inheritance of the trait in this dioecious species further exacerbates the propensity for its rapid spread. © 2017 Society of Chemical Industry
Using Academic Word Lists to Support Disciplinary Literacy Development
Authors: Joseph Picot Christine 
Published: May 2017

AbstractAn elementary mathematics coach describes her process and instructional strategies for using academic word lists to support students’ disciplinary literacy development. Using teacher coaching, the author explores methods for classroom teachers to embed and authentically integrate best practices in vocabulary instruction to support disciplinary literacy development. The author also provides classroom examples and student work to support recommended instructional strategies.
Influence of trap modifications and environmental predictors on capture success of southern flying squirrels
Authors: Jacques Christopher N. , Zweep James S. , Scheihing Mary E. , Rechkemmer Will T. , Jenkins Sean E. , Klaver Robert W. , Dubay Shelli A. 
Published: May 2017

ABSTRACTSherman traps are the most commonly used live traps in studies of small mammals and have been successfully used in the capture of arboreal species such as the southern flying squirrel (Glaucomys volans). However, southern flying squirrels spend proportionately less time foraging on the ground, which necessitates above‐ground trapping methods and modifications of capture protocols. Further, quantitative estimates of the factors affecting capture success of flying squirrel populations have focused solely on effects of trapping methodologies. We developed and evaluated the efficacy of a portable Sherman trap design for capturing southern flying squirrels during 2015–2016 at the Alice L. Kibbe Field Station, Illinois, USA. Additionally, we used logistic regression to quantify potential effects of time‐dependent (e.g., weather) and time‐independent (e.g., habitat, extrinsic) factors on capture success of southern flying squirrels. We recorded 165 capture events (119 F, 44 M, 2 unknown) using our modified Sherman trap design. Probability of capture success decreased 0.10/1° C increase in daily maximum temperature and by 0.09/unit increase (km/hr) in wind speed. Conversely, probability of capture success increased by 1.2/1° C increase in daily minimum temperature. The probability of capturing flying squirrels was negatively associated with trap orientation. When tree‐mounted traps are required, our modified trap design is a safe, efficient, and cost‐effective method of capturing animals when moderate weather (temp and wind speed) conditions prevail. Further, we believe that strategic placement of traps (e.g., northeast side of tree) and quantitative information on site‐specific (e.g., trap location) characteristics (e.g., topographical features, slope, aspect, climatologic factors) could increase southern flying squirrel capture success. © 2017 The Wildlife Society.
Analytical Prediction of Stability Lobes for Passively Damped Boring Bars
Authors: Fallah M. , Moetakef-Imani B. 
Published: May 2017

AbstractThe present article proposes the closed-form solution for analytical prediction of stability lobes in internal turning process. The passively damped boring bar is modeled as a cantilevered Euler-Bernoulli beam with constant cross sectional properties in which a Tuned Mass Damper (TMD) is embedded for the purpose of chatter suppression. The non-dimensional equations of motion are derived, assuming that the boring bar dynamics is well-represented by the fundamental mode of vibration. The stability of equivalent two-DOF dynamic model, i.e. boring bar with TMD, is analyzed in frequency domain. The closed- form expressions for critical depth of cut and spindle speed are presented in terms of boring bar and TMD characteristics. The proposed solution considers the effects of boring bar's structural damping and cutting geometry of insert on the stability behavior of passively damped cutting tool. An unconstrained optimization method is utilized to compute the most optimal set of tuning parameters for anti-chatter TMD. In order to improve the boundary of stability in a global sense, maximization of minimum critical depth of cut is selected as the objective of optimization. The superior performance of anti-chatter TMD is compared to H∞and H2TMDs for a wide range of applications. Moreover, the achieved results show a remarkable improvement of stability boundary compared to recent research works.
THE PRINCIPLE OF SYSTEMIC INTEGRATION IN HUMAN RIGHTS LAW
Authors: Rachovitsa Adamantia 
Published: May 2017

AbstractInternational lawyers and courts consider the principle of systemic integration to be a potential answer to difficulties arising from the fragmentation of public international law. This article questions the application of this approach in the context of human rights treaties. It is argued, first, that in many instances, systemic integration raises serious interpretational and jurisdictional concerns and, second, that systemic integration may give rise to a less diverse international law.
Dactylogyrids (Platyhelminthes, Monogenoidea) from the gills of Hoplias malabaricus (Characiformes: Erythrinidae) from coastal rivers of the Oriental Amazon Basin: species of Urocleidoides and Constrictoanchoratus n. gen.
Authors: Ferreira K.D.C. , Rodrigues A.R.O. , Cunha J.-M. , Domingues M.V. 
Published: May 2017

AbstractFive species of Urocleidoides (one new) and two new species of Constrictoanchoratus n. gen. are described in this study. All were collected from the gills of Hoplias malabaricus (Characiformes: Erythrinidae) captured in six localities of coastal rivers of the north-eastern sector the State of Pará (Oriental Amazon): Urocleidoides brasiliensis Rosim, Mendoza-Franco & Luque, 2011; Urocleidoides bulbophallus n. sp.; Urocleidoides cuiabai Rosim, Mendoza-Franco & Luque, 2011; Urocleidoides eremitus Kritsky, Thatcher & Boeger, 1986; Urocleidoides malabaricusi Rosim, Mendoza-Franco & Luque, 2011; Constrictoanchoratus lemmyi n. gen. n. sp.; and Constrictoanchoratus ptilonophallus n. gen. n. sp. This is the first reported occurrence of the four previously described species of Urocleidoides parasitizing H. malabaricus from streams in the Oriental Amazon Basin. The analysis of voucher specimens of U. eremitus parasitizing the gills of H. malabaricus from the Upper Paraná River floodplain in the limits of States of Paraná and Mato Grosso do Sul, Brazil, indicates that these specimens are members of a new species of Urocleidoides, described here as Urocleidoides paranae n. sp. Constrictoanchoratus n. gen. is proposed for the species with a male copulatory organ sclerotized, coiled, clockwise; ventral anchor with elongate superficial root, inconspicuous deep root; dorsal anchor with inconspicuous roots, and a constriction at the intersection between the shaft and the point. The host–parasite diversity scenario and host specificity of the species of Constrictoanchoratus n. gen. and Urocleidoides from the gills of H. malabaricus are also discussed in this study.
Infection, specificity and host manipulation ofAustralapatemonsp. (Trematoda, Strigeidae) in two sympatric species of leeches (Hirudinea)
Authors: KARVONEN ANSSI , FALTÝNKOVÁ ANNA , CHOO JOCELYN MAH , VALTONEN E. TELLERVO 
Published: May 2017

SUMMARYFactors that drive parasite specificity and differences in infection dynamics among alternative host species are important for ecology and evolution of host–parasite interactions, but still often poorly known in natural systems. Here, we investigated spatiotemporal dynamics of infection, host susceptibility and parasite-induced changes in host phenotype in a rarely explored host–parasite system, theAustralapatemonsp. trematode infecting two sympatric species of freshwater leeches,Erpobdella octoculataandHelobdella stagnalis. We show significant variation in infection abundance between the host species in both space and time. Using experimental infections, we also show that most of this variation likely comes from interspecific differences in exposure rather than susceptibility. Moreover, we demonstrate that the hiding behaviour ofE. octoculata, but not that ofH. stagnalis, was impaired by the infection irrespective of the parasite abundance. This may increase susceptibility ofE. octoculatato predation by the final avian host. We conclude that differences in patterns of infection and in behavioural alterations among alternative sympatric host species may arise in narrow spatial scales, which emphasises the importance of local infection and transmission dynamics for parasite life cycles.
Buffer zones: Anachronism, power vacuum, or confidence builder?
Authors: Menon Rajan , Snyder Jack L. 
Published: May 2017

AbstractAmidst calls for containing an assertive Russia, politicians and pundits have been debating whether Ukraine should serve as a ‘buffer zone’ between the Russian and Western spheres of influence. These debates provide an opportunity to revisit the long and varied history of major powers’ efforts to manage buffer zones. We draw on this history to learn the conditions under which buffer zones succeed or fail to stabilise regions, how buffers are most successfully managed, and when alternative arrangements for borderlands work better.
The Effects of Specific Learning Difficulties on Processes of Multilingual Language Development
Authors: Kormos Judit 
Published: May 2017

ABSTRACTThis article reviews current research findings on how specific learning difficulties (SLDs) impact on the processes of multilingual language development. The review includes studies of young language learners in instructed classroom settings, as well as of multilingual children in second language (L2) contexts. Starting with a definition of the concepts of disability and SLDs, it next discusses the interaction of cognitive factors with first language (L1) and L2 literacy development and L2 learning. Also outlined are possible ways in which SLDs can be identified in different L2 learning contexts. A detailed analysis of how cognitive factors influence the development of L2 skills of young learners with learning difficulties is given in the last part of the article.
Refining the Frommelt Attitude Toward the Care of the Dying Scale (FATCOD–B) for medical students: A confirmatory factor analysis and Rasch validation study
Authors: Loera Barbara , Molinengo Giorgia , Miniotti Marco , Leombruni Paolo 
Published: May 2017

ABSTRACTObjective:Given the increasing number of patients requiring palliative care and the need for more professionals who are able to provide care for the dying comfortably, assessment of medical attitudes toward end-of-life care is becoming a key aspect of medical education. The present study aimed to establish whether the Frommelt Attitude Toward the Care Of the Dying, Form B (FATCOD–B) meets current psychometric standards of validity for an assessment tool in medical education.Method:The participants were 200 undergraduate medical students. Since in a previous study the FATCOD–B was found to have a weak structure due to poor item validity, a refined version was proposed and tested in the present study. Confirmatory factor analysis and the Rasch model were employed to assess its dimensionality and psychometric properties.Results:The construct measured by the FATCOD–B continues to be misspecified. The tool has a two-dimensional structure. The first is well-structured and demonstrates appreciable measurement and discriminant capabilities. The second has low validity because its measurement capabilities are based on weakly correlated items.Significance of results:Our results suggest that the FATCOD–B measures a two-dimensional construct and that only its first dimension is a robust measurement tool for use in medical education to evaluate undergraduates' attitudes about caring for the dying.
MicroRNA-122 ameliorates corneal allograft rejection through the downregulation of its target CPEB1
Authors: Wang Ting , Li Fengjie , Geng Wenwen , Ruan Qingguo , Shi Weiyun 
Published: May 2017

AbstractTransplant rejection is a major cause of corneal transplantation failure. MicroRNAs (miRNAs) are a family of small RNAs that regulates gene expression in a sequence-specific manner. miRNAs have recently been shown to have important roles in human organ transplantation, but reports of miRNAs directly associated with corneal transplantation rejection remain limited. To investigate the role of miRNAs during corneal allograft rejection, we established a mouse penetrating keratoplasty model and used microarrays to screen for differentially expressed miRNAs. Our results revealed that the expression of miR-122 was significantly decreased in the allogeneic group. Consistent with this result, the expression of cytoplasmic polyadenylation element-binding protein-1 (CPEB1), a direct target of miR-122, was significantly increased. Further analysis demonstrated that miR-122 inhibited inflammatory cytokine-induced apoptosis in corneal keratocytes through the downregulation of its target CPEB1. We also found that increased miR-122 expression significantly reduced the risk of corneal transplantation rejection. Thus, our results indicate that miR-122 is an important miRNA associated with corneal graft rejection and can be used as a therapeutic target for the prevention of immune rejection after keratoplasty.
Energy efficiency to reduce residential electricity and natural gas use under climate change
Authors: Reyna Janet L. , Chester Mikhail V. 
Published: May 2017

AbstractClimate change could significantly affect consumer demand for energy in buildings, as changing temperatures may alter heating and cooling loads. Warming climates could also lead to the increased adoption and use of cooling technologies in buildings. We assess residential electricity and natural gas demand in Los Angeles, California under multiple climate change projections and investigate the potential for energy efficiency to offset increased demand. We calibrate residential energy use against metered data, accounting for differences in building materials and appliances. Under temperature increases, we find that without policy intervention, residential electricity demand could increase by as much as 41–87% between 2020 and 2060. However, aggressive policies aimed at upgrading heating/cooling systems and appliances could result in electricity use increases as low as 28%, potentially avoiding the installation of new generation capacity. We therefore recommend aggressive energy efficiency, in combination with low-carbon generation sources, to offset projected increases in residential energy demand.
New Blatter-type radicals from a bench-stable carbene
Authors: Grant Jacob A. , Lu Zhou , Tucker David E. , Hockin Bryony M. , Yufit Dmitry S. , Fox Mark A. , Kataky Ritu , Chechik Victor , O’Donoghue AnnMarie C. 
Published: May 2017

AbstractStable benzotriazinyl radicals (Blatter’s radicals) recently attracted considerable interest as building blocks for functional materials. The existing strategies to derivatize Blatter’s radicals are limited, however, and synthetic routes are complex. Here, we report that an inexpensive, commercially available, analytical reagent Nitron undergoes a previously unrecognized transformation in wet acetonitrile in the presence of air to yield a new Blatter-type radical with an amide group replacing a phenyl at the C(3)-position. This one-pot reaction of Nitron provides access to a range of previously inaccessible triazinyl radicals with excellent benchtop stabilities. Mechanistic investigation suggests that the reaction starts with a hydrolytic cleavage of the triazole ring followed by oxidative cyclization. Several derivatives of Nitron were prepared and converted into Blatter-type radicals to test the synthetic value of the new reaction. These results significantly expand the scope of using functionalized benzotriazinyls as stable radical building blocks.
Mid-infrared coincidence measurements on twin photons at room temperature
Authors: Mancinelli M. , Trenti A. , Piccione S. , Fontana G. , Dam J. S. , Tidemand-Lichtenberg P. , Pedersen C. , Pavesi L. 
Published: May 2017

AbstractQuantum measurements using single-photon detectors are opening interesting new perspectives in diverse fields such as remote sensing, quantum cryptography and quantum computing. A particularly demanding class of applications relies on the simultaneous detection of correlated single photons. In the visible and near infrared wavelength ranges suitable single-photon detectors do exist. However, low detector quantum efficiency or excessive noise has hampered their mid-infrared (MIR) counterpart. Fast and highly efficient single-photon detectors are thus highly sought after for MIR applications. Here we pave the way to quantum measurements in the MIR by the demonstration of a room temperature coincidence measurement with non-degenerate twin photons at about 3.1 μm. The experiment is based on the spectral translation of MIR radiation into the visible region, by means of efficient up-converter modules. The up-converted pairs are then detected with low-noise silicon avalanche photodiodes without the need for cryogenic cooling.
Explosive eruption, flank collapse and megatsunami at Tenerife ca. 170 ka
Authors: Paris Raphaël , Bravo Juan J. Coello , González María E. Martín , Kelfoun Karim , Nauret François 
Published: May 2017

AbstractGiant mass failures of oceanic shield volcanoes that generate tsunamis potentially represent a high-magnitude but low-frequency hazard, and it is actually difficult to infer the mechanisms and dynamics controlling them. Here we document tsunami deposits at high elevation (up to 132 m) on the north-western slopes of Tenerife, Canary Islands, as a new evidence of megatsunami generated by volcano flank failure. Analyses of the tsunami deposits demonstrate that two main tsunamis impacted the coasts of Tenerife 170 kyr ago. The first tsunami was generated during the submarine stage of a retrogressive failure of the northern flank of the island, whereas the second one followed the debris avalanche of the subaerial edifice and incorporated pumices from an on-going ignimbrite-forming eruption. Coupling between a massive retrogressive flank failure and a large explosive eruption represents a new type of volcano-tectonic event on oceanic shield volcanoes and a new hazard scenario.
YAP regulates cell mechanics by controlling focal adhesion assembly
Authors: Nardone Giorgia , Oliver-De La Cruz Jorge , Vrbsky Jan , Martini Cecilia , Pribyl Jan , Skládal Petr , Pešl Martin , Caluori Guido , Pagliari Stefania , Martino Fabiana , Maceckova Zuzana , Hajduch Marian , Sanz-Garcia Andres , Pugno Nicola Maria , Stokin Gorazd Bernard , Forte Giancarlo 
Published: May 2017

AbstractHippo effectors YAP/TAZ act as on–off mechanosensing switches by sensing modifications in extracellular matrix (ECM) composition and mechanics. The regulation of their activity has been described by a hierarchical model in which elements of Hippo pathway are under the control of focal adhesions (FAs). Here we unveil the molecular mechanism by which cell spreading and RhoA GTPase activity control FA formation through YAP to stabilize the anchorage of the actin cytoskeleton to the cell membrane. This mechanism requires YAP co-transcriptional function and involves the activation of genes encoding for integrins and FA docking proteins. Tuning YAP transcriptional activity leads to the modification of cell mechanics, force development and adhesion strength, and determines cell shape, migration and differentiation. These results provide new insights into the mechanism of YAP mechanosensing activity and qualify this Hippo effector as the key determinant of cell mechanics in response to ECM cues.
Food security is related to adult type 2 diabetes control over time in a United States safety net primary care clinic population
Authors: Shalowitz M U , Eng J S , McKinney C O , Krohn J , Lapin B , Wang C-H , Nodine E 
Published: May 2017

AbstractBackground/Objectives:Successful Type 2 diabetes management requires adopting a high nutrient-density diet made up of food items that both meet dietary needs and preferences and can be feasibly obtained on a regular basis. However, access to affordable, nutrient-dense foods often is lacking in poorer neighbourhoods. Therefore, low food security should directly impair glucose control, even when patients have full access to and utilize comprehensive medical management. The present study sought to determine whether food security is related longitudinally to glucose control, over-and-above ongoing medication management, among Type 2 diabetes patients receiving comprehensive care at a Midwestern multi-site federally qualified health centre (FQHC).Subjects/Methods:In this longitudinal observational study, we completed a baseline assessment of patients’ food security (using the US Household Food Security Module), demographics (via Census items), and diabetes history/management (using a structured clinical encounter form) when patients began receiving diabetes care at the health centre. We then recorded those patients’ A1C levels several times during a 24-month follow-up period. Three hundred and ninety-nine patients (56% with low food security) had a baseline A1c measurement; a subsample of 336 (median age=52 years; 56% female; 60% Hispanic, 27% African American, and 9% White) also had at least one follow-up A1c measurement.Results:Patients with lower (vs higher) food security were more likely to be on insulin and have higher A1c levels at baseline. Moreover, the disparity in glucose control by food security status persisted throughout the next 2 years.Conclusions:Although results were based on one multi-site FQHC, potentially limiting their generalizability, they seem to suggest that among Type 2 diabetes patients, low food security directly impairs glucose control—even when patients receive full access to comprehensive medical management—thereby increasing their long-term risks of high morbidity, early mortality, and high health-care utilization and cost.