bluuebunny/crossref_metadata_2025_split huggingface dataset:
Live Transport of Yellow Perch and Nile Tilapia in AQUI-S 20E (10% Eugenol) at High Loading Densities
Authors: Cupp Aaron R , Schreier Theresa M , Schleis Susan M 
Published: March 2017

Abstract
Fish transport costs are a substantial portion of the operational expenses for aquaculture facilities in the USA. Safely transporting higher loading densities of fish would benefit haulers by increasing efficiency and reducing costs, but research evaluating transport for individual species is generally lacking. In this study, Yellow Perch Perca flavescens and Nile Tilapia Oreochromis niloticus were transported for 6 h immersed in water containing AQUI-S 20E (10% eugenol) at fish loading densities of 240 g/L (2 lb/gal) for perch and 480 g/L (4 lb/gal) for tilapia. Survival was quantified for fish transported in AQUI-S 20E concentrations of (1) control or 0 mg/L of water, (2) 100 mg/L, or (3) 200 mg/L. Yellow Perch had 98–100% survival, and Nile Tilapia had 100% survival up to through 14 d after transport across all AQUI-S 20E levels, including the control. Eugenol concentrations decreased rapidly in transport tank water, and fish showed no signs of sedation by the end of transport. We conclude that live transport of Yellow Perch and Nile Tilapia at higher loading densities resulted in high survival regardless of the AQUI-S 20E concentrations we tested.
Metastatic Liposarcoma of the Skull Base: A Case Report and Review of Literature
Authors: Zagzoog Nirmeen , Ra Greta , Koziarz Alex , Provias John , Sommer Doron , Almenawer Saleh A. , Reddy Kesava 
Published: March 2017

Abstract

BACKGROUND AND IMPORTANCE: Myxoid liposarcoma is not an uncommon form of sarcoma. However, it usually affects the lower extremity long bones. Scapular involvement is extremely rare, as is a metastasis to the parasellar region. We present a case of liposarcoma of the skull base originating in the scapular region and metastasizing to the sellar and parasellar regions and provide a review of the pertinent literature.

CLINICAL PRESENTATION: A 43-year-old female patient diagnosed with left scapular myxoid liposarcoma was treated with surgical resection. She had clear resection margins and was treated pre- and postoperatively with radiotherapy to the region. She remained asymptomatic for 2 years following surgery, after which she abruptly developed diplopia with right lateral gaze. There were no symptoms of raised intracranial pressure or impaired vision. Her examination was normal apart from complete right sixth nerve palsy. Imaging studies of the brain showed a large mass in the clivus eroding into the floor of the sella, encircling the right internal carotid artery in the cavernous sinus. The mass also displaced the sellar contents superiorly. An endonasal, endoscopic skull base approach was undertaken, and a subtotal resection was performed in an effort to avoid multiple cranial nerve pareses.

CONCLUSION: Our literature search revealed that this case report is the first to document liposarcoma metastasis to the skull base originating from the scapular region. Subtotal surgical resection resulted in minimal improvement of the patient's sixth nerve palsy. Postoperative radiation was undertaken. A multidisciplinary approach on an individual patient basis is recommended.
C. elegansexhibits coordinated oscillation in gene activation in single-cell developmental data
Authors: Hutchison Luke A.D. , Berger Bonnie , Kohane Isaac 
Published: March 2017

AbstractBackgroundThe advent ofin vivoautomated single-cell lineaging and sequencing will dramatically increase our understanding of development. New integrative analysis techniques are needed to generate insights from single-cell developmental data.ResultsWe applied novel meta-analysis techniques to the EPIC single-cell-resolution developmental gene expression dataset forC. elegansto show that a simple linear combination of the expression levels of the developmental genes is strongly correlated with the developmental age of the organism, irrespective of the cell division rate of different cell lineages. We uncovered a pattern of collective sinusoidal oscillation in gene activation, in multiple dominant frequencies and in multiple orthogonal axes of gene expression, pointing to the existence of a coordinated, multi-frequency global timing mechanism. We developed a novel method based on Fisher’s Discriminant Analysis (FDA) to identify linear gene expression weightings that are able to produce sinusoidal oscillations of any frequency and phase, adding to the evidence that oscillatory mechanisms likely play an important role in the timing of development. We cross-linked EPIC with gene ontology and anatomy ontology terms, employing FDA methods to identify previously unknown positive and negative genetic contributions to developmental processes and cell phenotypes.ConclusionsThis meta-analysis demonstrates new evidence for direct linear and/or sinusoidal mechanisms regulating the timing of development. We uncovered a number of previously unknown positive and negative correlations between developmental genes and developmental processes or cell phenotypes. The presented novel analysis techniques are broadly applicable within developmental biology.
Older consumers’ TV shopping: emotions and satisfaction
Authors: Lim Chae Mi , Kim Youn-Kyung 
Published: March 2017

PurposeThe purpose of this paper is to identify the emotional factors that affect older consumers’ satisfaction with TV shopping and examined the relationships among these factors.Design/methodology/approachA sample of 285 consumers aged 60 years and older who had watched a TV home shopping channel was used. Structural equation modeling (SEM) examined the relationships among emotional factors that affect satisfaction.FindingsThis study found that loneliness was an antecedent of both gratification shopping motivation and telepresence and that telepresence positively affected consumer satisfaction with TV shopping.Research limitations/implicationsThe findings of this study validate social-compensation motive of media consumption and deficiency paradigm in the context of TV shopping. The relationship between telepresence and satisfaction also supported transportation theory. However, the findings of the current study should be interpreted with caution due to the non-random sampling method. Constructs other than those employed in this study could be examined regarding outcomes of loneliness.Practical implicationsThis study suggested that telepresence and shopping for self-gratification are effective ways to alleviate older consumers’ loneliness. In addition, the findings from relationships among emotional variables suggested potential marketing strategies for shaping positive consumer attitudes toward and satisfaction with TV shopping networks.Originality/valueThis study extended knowledge on loneliness by demonstrating how it related to attitudinal outcomes such as satisfaction and knowledge on telepresence by examining it in the context of TV shopping.
The state of social media engagement in Saudi universities
Authors: Alsufyan Norah Khalid , Aloud Monira 
Published: March 2017

Purpose
The purpose of this paper is to investigate the way that Saudi universities are engaging their audience via social media platforms by means of the five meaningful themes: visibility, branding, authenticity, commitment, and engagement. The study will answer the questions: how do Saudi universities exploit social media platforms to engage their target audience? What are the recommendations for Saudi universities toward maximizing the value of social media engagement?

Design/methodology/approach
A content analysis approach was used to study all Saudi universities (26 public, 11 private). Facebook, YouTube, LinkedIn and Twitter were the anticipated social media platforms in this study.

Findings
The results showed that Twitter is the most frequently used platform to communicate with audiences. While visibility in the anticipated social media platforms was high, the engagement was lacking. On the other hand, authenticity and branding in the anticipated social media platforms were medium, while commitment was low except on Twitter. In general, the private universities exceed the public universities in terms of visibility, branding, authenticity, commitment and engagement in the anticipated social media platforms, which indicates their attention on gaining their audience’s satisfaction, a dynamic of trust which will lead to maintaining current relationships or building new ones.

Originality/value
Since there are few studies in the field regarding social media platforms usage by Saudi universities, this study aims to understand how Saudi universities are utilizing social media platforms to engage their audiences and propose recommendations for how Saudi universities can build value from social media platforms.
Supervisor/peer involvement in evaluation Transfer of Training process and results reliability
Authors: Capaldo Guido , Depolo Marco , Rippa Pierluigi , Schiattone Domenico 
Published: March 2017

Purpose
The aim of this paper is to present a study performed in conjunction with a branch of the Italian Public Italian Administration, the ISSP (Istituto Superiore di Studi Penitenziari – the Higher Institute of Penitentiary Studies). The study aimed to develop a Transfer of Training (ToT) evaluation methodology that would be both scientifically robust and practitioner-friendly, in an attempt to build a bridge between researchers and practitioners on the topic of ToT process evaluation.

Design/methodology/approach
The ToT evaluation system was built using an action research approach, taking into account workplace specifics and stakeholder needs. An “action research” (with the researchers involved throughout the ToT system building phases) and a “Focus Group” (to identify factors influencing ToT and to define items and grids for behavioural assessment) were used.

Findings
This study showed that the active engagement of stakeholders (trainees and their supervisors and colleagues) is useful in designing context-adapted tools for ToT evaluation and can help organizations improve the fit between their training activities and organizational goals.

Research limitations/implications
The generalizability of the proposed ToT evaluation methodology is not guaranteed, and the procedure needs to be replicated and monitored in different organizational settings and cultures.

Practical implications
The organization decided to implement the ToT evaluation methodology developed during the course of the study for all future training programmes.

Originality/value
In this study, a ToT evaluation methodology was built that will be both scientifically robust and practitioner-friendly.
OligoG CF‐5/20 normalizes cystic fibrosis mucus by chelating calcium
Authors: Ermund Anna , Recktenwald Christian V , Skjåk‐Bræk Gudmund , Meiss Lauren N , Onsøyen Edvar , Rye Philip D , Dessen Arne , Myrset Astrid Hilde , Hansson Gunnar C 
Published: March 2017

SummaryThe goal of this study was to determine whether the guluronate (G) rich alginate OligoG CF‐5/20 (OligoG) could detach cystic fibrosis (CF) mucus by calcium chelation, which is also required for normal mucin unfolding. Since bicarbonate secretion is impaired in CF, leading to insufficient mucin unfolding and thereby attached mucus, and since bicarbonate has the ability to bind calcium, we hypothesized that the calcium chelating property of OligoG would lead to detachment of CF mucus. Indeed, OligoG could compete with the N‐terminus of the MUC2 mucin for calcium binding as shown by microscale thermophoresis. Further, effects on mucus thickness and attachment induced by OligoG and other alginate fractions of different length and composition were evaluated in explants of CF mouse ileum mounted in horizontal Ussing‐type chambers. OligoG at 1.5% caused effective detachment of CF mucus and the most potent alginate fraction tested, the poly‐G fraction of about 12 residues, had similar potency compared to OligoG whereas mannuronate‐rich (M) polymers had minimal effect. In conclusion, OligoG binds calcium with appropriate affinity without any overt harmful effect on the tissue and can be exploited for treating mucus stagnation.
Ageing in remote and cyclone‐prone communities: geography, policy, and disaster relief
Authors: Astill Sandra 
Published: March 2017

AbstractFocusing on the experience of independent‐living older adults, this study explored how those in regional Australian coastal communities have coped with repeated natural disasters. Using an exploratory, mixed‐method, and phenomenological approach, an array of non‐probability snowballing techniques was used to seek participation from residents aged 65 years or more, and from emergency services officers, disaster managers, and community health care providers located in regional communities affected by Cyclone Larry (2006) and Cyclone Yasi (2011). The research found that post‐disaster political decisions have had a negative long‐term impact on local economies, causing outmigration by those seeking employment, and resulting in many elderly residents facing a future without family support. As government policies encourage ageing‐in‐place by providing subsidised in situ care, increasingly older adults are remaining in exposed vulnerable locations, reliant on authorities for their survival both day‐to‐day and during an emergency. Findings also uncovered inconsistent disaster management policies between neighbouring local government councils and an unrealistic reliance on in situ care organisations by disaster managers during preparation and recovery stages of a natural hazard. These results highlight the need for those charged with emergency management to reassess both the future natural hazard adaptive capacities of ageing regional communities and policy responses to such challenges.
Functional responses of cougars (Puma concolor) in a multiple prey‐species system
Authors: SORIA‐DÍAZ Leroy , FOWLER Mike S. , MONROY‐VILCHIS Octavio , ORO Daniel 
Published: March 2017

AbstractThe study of predator–prey interactions is commonly analyzed using functional responses to gain an understanding of predation patterns and the impact they have on prey populations. Despite this, little is known about predator–prey systems with multiple prey species in sites near the equator. Here we studied the functional response of cougars (Puma concolor) in relation to their main prey, armadillo (Dasypus novemcinctus), coati (Nasua narica) and white‐tailed deer (Odocoileus virginianus). Between 2004 and 2010, cougar scats were collected along 5 transects to estimate the consumption of different prey species. A relative abundance index (RAI) was calculated for each prey species and cougar using 18 camera traps. We compared Holling type I, II and III functional response models to determine patterns in prey consumption based on the relative abundance and biomass of each prey species consumed. The 3 main prey species comprised 55% (armadillo), 17% (coati) and 8% (white‐tailed deer) of the diet. Type I and II functional responses described consumption of the 2 most common prey species armadillos and coati similarly well, while a type I response best characterized consumption of white‐tailed deer. A negative correlation between the proportions of armadillo versus coati and white‐tailed deer biomass in cougar scats suggests switching to consume alternative prey, confirming high foraging plasticity of this carnivore. This work represents one of the few studies to compare functional responses across multiple prey species, combined with evidence for prey‐switching at low densities of preferred prey.
Remote physiological ischemic training promotes coronary angiogenesis via molecular and cellular mobilization after myocardial ischemia
Authors: Zheng Yu , Xiao Mingyue , Li Ling , Li Jianan , Reinhardt Jan D. , Lu Xiao 
Published: March 2017

SummaryAimThis study was designed to explore the mechanism of physiological ischemic training (PIT) on remote limbs, with a special focus on the potential role of endothelial progenitor cells (EPCs), vascular endothelial growth factor (VEGF), and nitric oxide (NO) in local ischemic myocardium.MethodMyocardial ischemia (MI) rabbit models were randomly assigned to sham‐operated group (SO), training‐only group (TO), MI group, PIT group, VEGF inhibitor group (VEGF‐), NO inhibitor group (NO‐), VEGF and NO inhibitor group (VEGF‐/NO‐), and EPC inhibitor group (EPC‐). A constrictor was implanted around the left ventricular branch to induce controlled MI. The PIT procedure consisted of three cycles of a 3‐minutes cuff inflation on the hindlimbs with a reperfusion of 5 minutes. Plasma and myocardial EPC numbers, VEGF level, and NO concentration, as well as capillary density (CD), coronary blood flow (CBF), and coronary collateral blood flow (CCBF) in myocardium, were measured.ResultsNonparametric statistical techniques were applied to identify the differences between groups, and regression models were used to detect correlations between agents. VEGF levels, NO concentrations, and also EPC counts in both plasma and myocardium were highest in the PIT group. Capillary density, CCBF, and CCBF/CBF were also statistically elevated in the PIT group. VEGF explained 74% of variance in NO. NO explained 65% of variance in EPCs. EPCs explained 68% of variance in capillary density. Capillary density explained 78% of variance in CCBF and CCBF/CBF.ConclusionPIT mobilized EPCs and promoted revascularization through upregulating VEGF and NO level.
Loss of phosphatase and tensin homolog expression correlates with clinicopathological features of non‐small cell lung cancer patients and its impact on survival: A systematic review and meta‐analysis
Authors: Zhao Yongsheng , Zheng Renyan , Li Jian , Lin Feng , Liu Lunxu 
Published: March 2017

BackgroundPhosphatase and tensin homolog (
PTEN
), regarded as a tumor suppressor gene, may act as a prognostic biomarker in human cancers.MethodsAll eligible studies from MEDLINE, Embase, CENTRAL, and the Chinese BioMedical Literature Database to October 2016 were incorporated. Two reviewers independently screened the literature according to inclusion and exclusion criteria, extracted the data, assessed the methodological quality of the included studies, and conducted meta‐analysis.ResultsA total of 2486 patients from 19 studies were included. PTEN expression was significantly correlated with gender, smoking history, histology (adenocarcinoma [ADC] vs. squamous cell carcinoma), tumor node metastasis stage (I–II vs. III–IV), N status (N0 vs. N1–N3), and distant metastasis (M0 vs. M1). Loss of PTEN expression was associated with poorer overall survival, but had no significant association with disease‐free survival. Subgroup analysis showed that negative PTEN expression was associated with a poorer outcome in Asian and ADC patients, but not in Western or squamous cell carcinoma patients.ConclusionLoss of PTEN might play an unfavorable prognostic role for overall survival of non‐small cell lung cancer patients, especially Asian or ADC patients.
Management of postoperative pain in Spain: a nationwide survey of practice
Authors: Montes A. , Aguilar J. L. , Benito M. C. , Caba F. , Margarit C. ,   Acute Pain Group of the Spanish Pain Society (SED)
Published: March 2017

BackgroundAlthough the need for structured assessment and management of acute postoperative pain has been recognized, practices and responsibilities vary between and within hospitals and countries. We sought to determine current pain management practices in Spanish hospitals with and without acute pain services (APSs) or acute pain management programmes (APMPs) and compare them to practices reported for 1997–1998.MethodsMembers of the Spanish Pain Society and APS/APMP heads were asked to respond to a survey. Responses were stratified by hospital size (< 200 or ≥ 200 beds) and APS/APMP presence or not. Categorical variables were described by percentages and the 95% confidence interval and continuous ones by the median and interquartile range.ResultsResponses were received from 42.4% of hospitals with ≥ 200 beds (vs. 9.6% of the smaller ones). We fully analysed only data for the larger hospitals, 57.7% of which had an APS or APMP. Full‐time pain physicians were on staff in 28.6% of large hospitals; 25% had full‐time nurses. Patients received written information about postoperative pain in 34.8% of APS/APMP hospitals, and 72% of them recorded pain assessments routinely. Protocols reflected interdepartmental consensus in 80.8%; training in postoperative pain was organised in 54%. Respondents thought pain was well or very well managed in 46.4%. In APS/APMP hospitals the following results had improved: provision of written information for patients (58.5% vs. 0%), the recording of pain assessments (93% vs. 43.8%), consensus on a pain scale (92.5% vs. 41.9%), use of protocols (99.7% vs. 55.2%), analysis of quality indicators (52.8% vs. 15.4%), training (73% vs. 26.9%), and respondents’ satisfaction with pain management in their hospital (68.6% vs. 9.5%).ConclusionsThe presence of an APS or APMP is associated with better results on indicators of quality of acute postoperative pain management.
Environmental and spatial drivers of spider diversity at contrasting microhabitats
Authors: Barton Philip S. , Evans Maldwyn J. , Foster Claire N. , Cunningham Saul A. , Manning Adrian D. 
Published: March 2017

AbstractThe relative importance of environmental and spatial drivers of animal diversity varies across scales, but identifying these scales can be difficult if a sampling design does not match the scale of the target organisms' interaction with their habitat. In this study, we quantify and compare the effects of environmental variation and spatial proximity on ground‐dwelling spider assemblages sampled from three distinct microhabitat types (open grassland, logs, trees) that recur across structurally heterogeneous grassy woodlands. We used model selection and multivariate procedures to compare the effects of different environmental attributes and spatial proximity on spider assemblages at each microhabitat type. We found that species richness and assemblage composition differed among microhabitat types. Bare ground cover had a negative effect on spider richness under trees, but a positive effect on spider richness in open grassland. Turnover in spider assemblages from open grassland was correlated with environmental distance, but not geographic distance. By contrast, turnover in spiders at logs and trees was correlated with geographic distance, but not environmental distance. Our study suggests that spider assemblages from widespread and connected open grassland habitat were more affected by environmental than spatial gradients, whereas spiders at log and tree habitats were more affected by spatial distance among these discrete but recurring microhabitats. Deliberate selection and sampling of small‐scale habitat features can provide robust information about the drivers of arthropod diversity and turnover in landscapes.