bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing crisis spillover risks: The role of perceived severity and corporate response effectiveness in China
Authors: Wang Yijing , Laufer Daniel , Ding Jia 
Published: September 2024

AbstractAlthough the spillover effect of crises represents an emerging area of interest within crisis communication studies, the perspective of consumers on the risk of crisis spillover as a result of corporate misconduct by another company remains underexplored in emerging markets like China. This study aims to fill the void through assessing how the severity of a crisis and the strategic responses by companies influence consumer perceptions of spillover risks from corporate misconduct by another company. A pre‐test (N = 120) determined two corporate misconducts as characteristic for the automotive industry in China. These scenarios were utilized in an online experiment (N = 320) to examine the effects of two crisis response strategies (issuing a denial vs. giving no response) by a competitor automaker. The results reveal that when a corporate misconduct is perceived as more severe, the perceived crisis spillover risks to the industry is higher; this perceived risk mediates the impact of crisis severity on negative word‐of‐mouth. Issuing a denial is more effective than giving no response, and leads to more positive consumer outcomes. This research unravels the complex dynamics at play in shaping consumer attitudes towards companies indirectly impacted by a crisis through a spillover effect.
Investigating proxies for retail investor attention in financial markets
Authors: Cahill Daniel , Liu Zhangxin (Frank) , Smales Lee A. 
Published: September 2024

AbstractInvestor attention influences financial markets but “depends on where you search” (Ben‐Rephael et al., The Review of Financial Studies, 2017, 30, 3009). We explore various retail investor attention proxies and their correlations with company characteristics and market reactions. Individually, retail attention proxies have a similar positive association with post‐earnings cumulative abnormal returns; however collectively, only abnormal Twitter (now X) attention remains significant after accounting for other retail attention metrics. Simultaneously high abnormal attention in all proxies captures a subsample that exhibits a post‐earnings announcement drift, contradicting the hypothesis that higher investor attention attenuates such drifts. Using vector autoregression, we find Twitter attention leads other retail attention proxies.
Sleep disorders and orofacial pain: insights for dental practice
Authors: McCloy K , Herrero Babiloni A , Sessle BJ 
Published: September 2024

AbstractIn dental sleep medicine several sleep disorders commonly coexist with pain, contributing to complex clinical presentations which might affect the provision of appropriate and timely treatment. There are associations between sleep disorders and pain in general, as well as with specific orofacial pain conditions. As many as five of six patients with orofacial pain can present with sleep problems. The comorbidity of orofacial pain and sleep disorders overlays a complex web of altered neurobiological mechanisms that predispose to the chronification of orofacial pain. This review discusses the relationship between orofacial pain and sleep disorders and highlights their interactions and the neurobiological mechanisms underlying those relationships.
Thermal balance in Andean lizards: A perspective from the high mountains
Authors: Montoya‐Cruz Alexandra , Díaz‐Flórez Ronald A. , Carvajalino‐Fernández Juan Manuel 
Published: September 2024

AbstractHigh Andean lizards in the Andes face numerous challenges in high‐altitude environments characterized by significant temperature, spatial and temporal variations. These factors greatly influence their thermal characteristics and adaptive strategies for coping with temperature fluctuations. This study aims were to investigate the thermal biology of high mountain lizards (>2000 m) inhabiting the Andes Mountain range, using information from existing literature, and to identify the potential impacts of the original climate change scenarios developed in this study. Within the Andes, high‐altitude species are primarily found in families like Liolaemidae, Gymnophthalmidae, Tropiduridae, Anolidae and Leiourisauridae. Notably, we found in the literature that the higher body temperatures and maximum critical temperatures in southern species compared to those closer to the tropics. Typically, diurnal and seasonal temperature variations have a significant impact on the body temperature of these high‐altitude lizards, but their adaptive behaviours and physiological mechanisms enhance their resistance to extreme temperatures. Populations situated below the equator often exhibit higher body temperatures and maximum critical temperatures, largely due to their exposure to higher ambient temperatures during summer. With all global warming scenarios indicating temperature increases in latitudinal regions, tropical high‐altitude lizards, historically less thermally adaptable, may be particularly susceptible to these temperature rises. It is crucial to consider that additional factors, such as species activity patterns, thermal resource availability and diminishing suitable thermal habitats, will also play a pivotal role in shaping the future of these lizard species, making the situation even more complex and challenging.
Thirty years of stasis in the dynamics of the Knysna Afro‐montane forest, South Africa
Authors: Midgley Jeremy J. , Cramer Michael D. , Durrheim Graham 
Published: September 2024

AbstractWe analysed nearly 31 years (1991–2022) of tree population dynamics in 108 permanent plots each 0.04 ha of the Lilyvlei Nature Reserve, a section of the Knysna Forest in South Africa which has not historically been disturbed by harvesting. The Knysna Forest is the only large piece of forest in South Africa and is marginal for tall forest, having low mean annual rainfall of only about 1000 mm and occurs on nutrient poor soils. In contrast to many studies of other forests globally, we found almost no change in overall biomass. Even at the scale of our small plots and on 10–30 year time scales, there has been little change. The forest has very low recruitment and mortality rates and thus low growth rates. Climatic changes too were minimal over this 30‐year period. The proportion of stems that died per size class was concentrated in the larger size‐classes per species, even for shorter species. This suggests that senescence rather than external disturbances determines the low mortality and thus the low dynamism and the high biomass (approx. 600 Mg ha−1AGB or 41 m2 ha−1 basal area) of the forest. Mortality of some species exceeded conspecific recruitment, a trend accompanied by non‐significant declines in biomass. However, these trends are not significant. In conclusion, neither composition nor biomass has changed significantly in these forests over a period of 30 years. This suggests that not all Southern Hemisphere forests are in a state of decline.
Metabolic dysfunction‐associated steatotic liver disease and MetALD increases the risk of liver cancer and gastrointestinal cancer: A nationwide cohort study
Authors: Park Yewan , Jung Jooyi , Han Seungbong , Kim Gi‐Ae 
Published: September 2024

SummaryBackgroundThe new nomenclature of metabolic dysfunction‐associated steatotic liver disease (MASLD) substituting nonalcoholic fatty liver disease was proposed along with a new category of MASLD with increased alcohol intake (MetALD).AimsWe aimed to explore the cancer risk by MASLD and MetALD.MethodsThis nationwide cohort study included 3,596,709 participants who underwent a health check‐up in 2011 in South Korea. Steatotic liver disease (SLD) was defined as a fatty liver index ≥30. Participants were categorized into four exclusive groups: MASLD, MetALD, other combination aetiology and no SLD. The subdistribution hazard ratio (SHR) was calculated using the Fine–Gray model after adjusting other variables.ResultsDuring the 33.9 million person‐years of follow‐up, 285,845 participants (7.9%) developed cancers. Compared with no SLD, MASLD, MetALD and other combination aetiology had an increased risk of all cancer. Liver cancer risk escalated from no SLD to MASLD (SHR, 1.16; 95% CI, 1.12–1.21), MetALD (SHR, 2.06; 95% CI, 1.92–2.20) and other combination aetiology (SHR, 8.16; 95% CI, 7.69–8.67). Gastrointestinal cancers including oesophagus, stomach, colorectal, biliary and pancreas cancers increased in MASLD (SHR, 1.13; 95% CI, 1.11–1.15), MetALD (SHR, 1.17; 95% CI, 1.14–1.21) and other combination aetiology (SHR, 1.09; 95% CI, 1.05–1.13). A modest increase in lung cancer and hormone‐sensitive cancer was observed with MASLD.ConclusionsThis study showed that MASLD and MetALD are associated with an increased risk of cancer, particularly liver and gastrointestinal cancers. The findings build new evidence for the clinical outcomes of MetALD while highlighting the importance of managing alcohol intake properly in MASLD and MetALD.
Just go with your body? A conversation analytic study of the transition from first to second stage of labor in UK midwife‐led care
Authors: Jackson Clare , Beynon‐Jones Siân 
Published: September 2024

AbstractBackgroundThe transition from first to second stage of labor is poorly understood. While the onset of second stage is defined by cervical measurement, dilation cannot be directly sensed or externally observed. Thus, uncertainty exists when women report pushing urges before dilation is confirmed. This study aimed to explore how sensations of pushing and uncertainty over progress are interactionally managed.MethodsWe audio/video recorded the labors of 37 women in two midwife‐led units in England. Our analysis focused on a subset of 28 recordings that featured discussion of transition from first to second stage of labor. The interactions between midwives, laboring women and their birth partners were transcribed and analyzed using conversation analysis.ResultsWe identified a ‘pushing until proven otherwise’ rule granting temporary, contingent authority to bodily urges to push while tracking progress over time. Specifically, midwives supported reported pushing sensations without insisting on examinations. Caution was occasionally expressed in distinguishing between irresistible and forced pushing. Across multiple contractions, midwives watched and waited for alignment of sensations with signs of descent. Where signs of progress were absent over time, examinations were treated as clinically indicated.DiscussionThus, a complex interplay of women's sensations and midwifery expertise produced care. Compared to past research, our analysis demonstrates increased validation of embodied experience in contemporary midwife‐led practice. However, uncertainty still requires navigation through collaborative work. We evidence how this navigation is accomplished in real‐time interactions.
Children's and adolescents' expectations, evaluations and reasoning about a bystander who challenges social exclusion within intragroup and intergroup peer contexts
Authors: Yüksel Ayşe Şule , Palmer Sally B. , Argyri Eirini K. , Rutland Adam 
Published: September 2024

AbstractThis paper examined British children's (8‐ to 10‐year‐olds) and adolescents' (13‐ to 15‐year‐olds, N = 340; Female N = 171, 50.3%) expectations, evaluations and reasoning about a bystander peer who challenges the social exclusion of an immigrant or non‐immigrant peer by a peer group of non‐immigrant students. Participants read a hypothetical scenario in which a peer was excluded from an afterschool club by the peer group. The scenarios were either intergroup or intragroup contexts. Participants' expectations of a peer bystander challenging the social exclusion by the peer group, their perception of how the peer group would evaluate the challenger, and their reasoning around their expectations were measured. Adolescents were less likely to expect a peer bystander to challenge exclusion compared to children. Participants' perceptions of how the group would evaluate the challenger were significantly lower in intergroup compared to intragroup contexts. In intergroup contexts, adolescents with low expectations of challenging favoured group dynamics and group repercussions reasoning over moral reasoning, while children did not use group repercussions reasoning.
Therapeutic and pharmacological applications of extracellular vesicles and lipoproteins
Authors: Németh Krisztina , Kestecher Brachyahu M. , Ghosal Sayam , Bodnár Bernadett R. , Kittel Ágnes , Hambalkó Szabolcs , Kovácsházi Csenger , Giricz Zoltán , Ferdinandy Péter , Osteikoetxea Xabier , Burkhardt Ralph , Buzas Edit I. , Orsó Evelyn 
Published: September 2024

AbstractIn recent years, various approaches have been undertaken to eliminate lipoproteins co‐isolated with extracellular vesicles, as they were initially regarded as contaminating entities. However, novel discoveries are reshaping our perspective. In body fluids, these distinct particles not only co‐exist, but also interactions between them are likely to occur. Extracellular vesicles and lipoproteins can associate with each other, share cargo, influence each other's functions, and jointly have a role in the pathomechanisms of diseases. Additionally, their association carries important implications for therapeutic and pharmacological aspects of lipid‐lowering strategies. Extracellular vesicles and lipoprotein particles may have roles in the elimination of each other from the circulation. The objective of this minireview is to delve into these aspects. Here, we show that under certain physiological and pathological conditions, extracellular vesicles and lipoproteins are ‘partners’ rather than ‘strangers’ or ‘rivals’.
Tetrabenazine, a vesicular monoamine transporter 2 inhibitor, inhibits vesicular storage capacity and release of monoamine transmitters in mouse brain tissue
Authors: Tod Pál , Varga Anita , Román Viktor , Lendvai Balázs , Pálkovács Roland , Sperlágh Beáta , Vizi E. Sylvester 
Published: September 2024

AbstractBackground and PurposeTetrabenazine (TBZ), used for treating hyperkinetic disorders, inhibits vesicular monoamine transporter‐2 (VMAT‐2), which sequesters monoamines into vesicles for exocytosis. However, our knowledge of the effect of TBZ on monoaminergic transmission is limited. Herein, we provide neurochemical evidence regarding the effect of VMAT‐2 inhibition on vesicular neurotransmitter release from the prefrontal cortex (PFC) and striatum (STR) (brain regions involved in characteristic TBZ treatment side effects). The interaction between TBZ and MDMA was also assessed regarding motor behaviour in mice.Experimental ApproachVesicular storage capacity and release of [3H]‐noradrenaline ([3H]‐NA), [3H]‐dopamine ([3H]‐DA), [3H]‐serotonin ([3H]‐5‐HT), and [3H]‐acetylcholine ([3H]‐ACh) was studied in mouse PFC and STR ex vivo slice preparations using electrical field stimulation. Additionally, locomotor activity was assessed in vehicle‐treated mice and compared with that of MDMA, TBZ, and co‐administered animals (n = 6) using the LABORAS system.Key ResultsTBZ lowered the storage capacity and inhibited the vesicular release of [3H]‐NA and [3H]‐DA from the PFC, and [3H]‐DA and [3H]‐5‐HT from the STR in a concentration‐dependent manner. Unlike vesamicol (vesicular ACh uptake inhibitor), TBZ failed to inhibit the vesicular release of [3H]‐ACh from the PFC. When the vesicular storage of the investigated monoamines was inhibited by TBZ in the PFC and STR, MDMA induced the release of transmitters through transporter reversal; MDMA dose dependently increased locomotor activity in vivo.Conclusion and ImplicationsOur observations provide neurochemical evidence explaining the mechanism of VMAT‐2 inhibitors in the brain and support the involvement of dopaminergic and noradrenergic transmission in hyperkinetic movement disorders.
Examining the relationship between channel disintermediation and chemical fertilizer application: Empirical evidence from smallholder farmers in central China
Authors: Zhou Chunchi , Ruiz‐Menjivar Jorge , Zhang Lu 
Published: September 2024

AbstractDigital advancements have reshaped the sales channels for industrial products like chemical fertilizers, allowing for the elimination of certain intermediaries. Utilizing survey data from 1374 rice‐growing smallholder farmers across counties in central China, this study explored the impact of disintermediation in chemical fertilizer sales channels on application rates among smallholder farmers. Benchmark regression analyses indicated that channel disintermediation significantly decreased chemical fertilizer application across various scenarios. Additionally, the alignment of contractual factors and technical services between chemical suppliers and farmers, facilitated by disintermediation, reduced chemical fertilizer application. Heterogeneity analysis revealed that the reduction in chemical fertilizer application due to channel disintermediation was more pronounced among farmers with higher digital literacy or lower production capacity. These findings highlighted the importance of encouraging chemical suppliers with direct‐to‐consumer channels to enhance their technical services and increase supervision over the quality of their products and services, thereby building trust among farmers and facilitating their adaptation to changes in the sales channel structure.
How Do Chinese Exporting Firms Respond to Environment‐related Notifications? A Green Innovation Perspective
Authors: Chen Wen , Fan Yinzi 
Published: September 2024

AbstractEnvironment‐related notifications play an important role in the coordinated development of trade and environment protection. In this paper, we examine how Chinese exporting enterprises responded to environment‐related notifications implemented by the US through green innovation practices. These notifications significantly encouraged exporting firms to increase green innovation, as evidenced particularly by the number of green utility model patents granted. This effect was most pronounced in non‐foreign‐invested enterprises, high‐total‐factor‐productivity firms, technology‐intensive industries, and nongreen industries. These notifications also increased the probability of enterprises exiting the market while reducing the probability of new enterprises entering it. The innovation motivation of surviving firms was higher than that of the new entrants. Our analysis also suggests that environment‐related notifications had a crowding‐out effect on other innovation rather than a leverage effect. This study offers important empirical evidence that helps enterprises to respond to green non‐tariff measures effectively, enrich the existing literature, and provide practical guidance for both policymaking and corporate development.
Does Structural Matching between Finance and Law Promote Economic Development?
Authors: Wang Baifang 
Published: September 2024

AbstractFinancial systems generally operate under two different models: one where capital markets play a primary role in financial transactions and resource allocation (market‐oriented model), and another where banks are the central institutions for these activities (bank‐oriented model). The degree of investor protection afforded by the legal system varies across these systems. What is the most efficient alignment between financial structure and investor protection? This paper attempts to quantify the structural matching relationship between the financial structure and investor protection in various countries, and examines empirically the impact of this relationship on economic development. Using a sample of cross‐country panel data, it finds that the degree of structural matching was positively related to economic development. Both the combination of a securities market and strong investor protection and the combination of a banking system and weak investor protection can contribute to promoting economic development. It extends the law and finance theory framework, enhances the analysis of scenarios with weak alignment between financial structure and investor protection, explains the growth path of developing countries, and highlights the diversity and the dynamic nature of the optimal financial structure.
The Frontiers in Manufacturing Technologies Initiative and University Innovation
Authors: Leng Xuan , Zhang Yichuan 
Published: September 2024

AbstractBasic innovation, with universities as a key driver, is essential for advancing core technologies in the manufacturing industry. This study used a manufacturing technologies initiative as a natural experiment, combining funding and its outcomes data from the National Natural Science Foundation of China to construct a difference‐in‐differences model. It found that the Frontiers in Manufacturing Technologies Initiative had a positive effect on university innovation, particularly by increasing the number of university patents. Mechanism analysis showed that the policy mainly encouraged university innovation through university‐industry collaboration. The effect was more salient in universities with stronger basic research capabilities and those whose research fields matched strategic emerging industries covered by the initiative. This study underscores the crucial role of the Frontiers in Manufacturing Technologies Initiative in enhancing university‐led innovation. It highlights the effectiveness of industry‐academia partnerships in advancing technology, particularly in emerging strategic industries.
Establishment and characterization of mouse lines useful for endogenous protein degradation via an improved auxin‐inducible degron system (AID2)
Authors: Makino‐Itou Hatsune , Yamatani Noriko , Okubo Akemi , Kiso Makoto , Ajima Rieko , Kanemaki Masato T. , Saga Yumiko 
Published: September 2024

AbstractThe development of new technologies opens new avenues in the research field. Gene knockout is a key method for analyzing gene function in mice. Currently, conditional gene knockout strategies are employed to examine temporal and spatial gene function. However, phenotypes are sometimes not observed because of the time required for depletion due to the long half‐life of the target proteins. Protein knockdown using an improved auxin‐inducible degron system, AID2, overcomes such difficulties owing to rapid and efficient target depletion. We observed depletion of AID‐tagged proteins within a few to several hours by a simple intraperitoneal injection of the auxin analog, 5‐Ph‐IAA, which is much shorter than the time required for target depletion using conditional gene knockout. Importantly, the loss of protein is reversible, making protein knockdown useful to measure the effects of transient loss of protein function. Here, we also established several mouse lines useful for AID2‐medicated protein knockdown, which include knock‐in mouse lines in the ROSA26 locus; one expresses TIR1(F74G), and the other is the reporter expressing AID‐mCherry. We also established a germ‐cell‐specific TIR1 line and confirmed the protein knockdown specificity. In addition, we introduced an AID tag to an endogenous protein, DCP2 via the CAS9‐mediated gene editing method. We confirmed that the protein was effectively eliminated by TIR1(F74G), which resulted in the similar phenotype observed in knockout mouse within 20 h.