bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mutation of the SUMOylation site of Aurora-B disrupts spindle formation and chromosome alignment in oocytes
Authors: Chen Shan-Shan , Li Li , Yao Bo , Guo Jia-Lun , Lu Ping-Shuang , Zhang Hao-Lin , Zhang Kun-Huan , Zou Yuan-Jing , Luo Nan-Jian , Sun Shao-Chen , Hu Lin-Lin , Ren Yan-Ping 
Published: October 2024

AbstractAurora-B is a kinase that regulates spindle assembly and kinetochore-microtubule (KT-MT) attachment during mitosis and meiosis. SUMOylation is involved in the oocyte meiosis regulation through promoting spindle assembly and chromosome segregation, but its substrates to support this function is still unknown. It is reported that Aurora-B is SUMOylated in somatic cells, and SUMOylated Aurora-B contributes the process of mitosis. However, whether Aurora-B is SUMOylated in oocytes and how SUMOylation of Aurora-B impacts its function in oocyte meiosis remain poorly understood. In this study, we report that Aurora-B is modified by SUMOylation in mouse oocytes. The results show that Aurora-B colocalized and interacted with SUMO-2/3 in mouse oocytes, confirming that Aurora-B is modified by SUMO-2/3 in this system. Compared with that in young mice, the protein expression of SUMO-2/3 decreased in the oocytes of aged mice, indicating that SUMOylation might be related to mouse aging. Overexpression of Aurora-B SUMOylation site mutants, Aurora-BK207R and Aurora-BK292R, inhibited Aurora-B recruitment and first polar body extrusion, disrupting localization of gamma tubulin, spindle formation and chromosome alignment in oocytes. The results show that it was related to decreased recruitment of p-HDAC6 which induces the high stability of whole spindle microtubules including the microtubules of both correct and wrong KT-MT attachments though increased acetylation of microtubules. Therefore, our results corroborate the notion that Aurora-B activity is regulated by SUMO-2/3 in oocytes, and that SUMOylated Aurora B plays an important role in spindle formation and chromosome alignment.
Changes in breast cancer incidence and surgical treatment in Baden–Württemberg (Germany) during the COVID-19 pandemic
Authors: Jansen Lina , Hermann Silke , Bergbold Susanne , Arndt Volker 
Published: October 2024

AbstractThe COVID-19 pandemic affected the diagnostics and treatment of breast cancer. Numerous studies reported an early decline in breast cancer (BC) incidence during the COVID-19 pandemic. Less evidence is available on changes in medical care. Reports from individual patients have provided anecdotal evidence for a shift from breast-conserving surgery to mastectomy to reduce the number of visits to radiation units during the pandemic. This study aimed to explore changes in BC incidence and surgical treatment in the south of Germany. Using data from the Baden-Württemberg Cancer Registry, the age-standardized incidence of BC (ICD-10 C50 and D05) (women) in 2018–2021 was investigated overall and by age and stage using standardized incidence ratios. Among pre-operative stage I/IIA BC patients, differences in the time to surgery and type of surgery were investigated using negative binomial and logistic regression models. The incidence of invasive BC decreased significantly from 170.9 per 100,000 women in 2018/2019 to 159.7 in 2020 and increased to 169.2 in 2021. This decrease resulted from a lower incidence around April 2020 and was also observed for non-invasive BC. In 2021, incidence of invasive BC was still decreased by 8% in women aged 80 + years. Surgical treatment was analyzed in 22,708 BC patients with a pre-operative stage ≤ IIA. The median time to surgery was 33 days in 2018/2019, 32 days in 2020 and 36 days in 2021. The proportion of mastectomies increased from 16.1% in 2018/2019 to 17.1% in 2020 and 17.3% in 2021 (adjusted odds ratio and 95% confidence interval (2021 vs. 2018/2019): 1.13 (1.03–1.24)). The adjusted increase was strongest for patients aged 50–59 years (1.34 (1.09–1.64)) and those with high-grade tumors (1.27 (1.07–1.51)). While the early return to pre-pandemic age-standardized BC incidence rates is promising, missed cases have not been caught up until 2021. Furthermore, the decreased incidence in elderly women in 2021 warrants further attention. In early-stage BC, a slightly greater rate of mastectomies was observed, although such a change was not recommended. This result underlines the importance of good communication of adapted treatment guidelines in such exceptional circumstances.
Solvent mediated synthesis of multicolor narrow bandwidth emissive carbon quantum dots and their potential in white light emitting diodes
Authors: Sami Mohamed , El-Khouly Mohamed E. , Ghali Mohsen 
Published: October 2024

AbstractThe development of efficient and environmentally sustainable materials for white light-emitting diodes (WLEDs) is of paramount importance in the field of lighting technology. In this study, we present a solvent-modulated synthesis approach for the fabrication of multicolor narrow-bandwidth emissive carbon quantum dots (CQDs) as a promising solution for constructing WLEDs. The synthesis method involves the controlled reaction of organic precursors in different solvent environments, leading to the formation of CQDs with distinct emission wavelengths with a relatively small full width at half maximum, ranging from 28 to 42 nm. Moreover, these synthesized multicolor CQDs demonstrate a remarkably high fluorescence quantum yield of up to 65%, indicating their potential for constructing efficient WLED when incorporated in polymer matrix and coated on the surface of blue light-emitting diode (LED).
Groundwater-surface interaction amplified post-seismic streamflow fluctuation
Authors: Wang Chi-Yuen , Wang Lee-Ping , Manga Michael , Liang Xiuyu 
Published: October 2024

AbstractFollowing the 2014 South Napa earthquake near the end of a long drought in Central California, streamflow in Sonoma Creek increased and showed amplified daily fluctuation. However, no such changes occurred in the shallow groundwater. Here we show that the amplified fluctuation reflected increased interaction between the post-seismic rising water table and plant roots in the riparian zone, according to results from numerical simulation constrained by streamflow data and hydraulic properties of riparian sediments. Evapotranspiration during the day kept the water table low beneath the riparian zone, lowering the discharge to the stream. At night, the water table rose and increased discharge to the stream. The study also show substantial spatial difference in earthquake-induced interactions between groundwater and the surface, which may influence our understanding of the spatial scale of earthquake impacts on vegetation and ecosystems.
DFT-based 11B solid-state NMR calculations for guiding fine local structure identification and phase-property modulation in ZnxY1−xBO3–0.5x borate oxide ion conductors
Authors: Gou Yuan , Li Xiaohui , Wang Xiaoge , Zhang Mengjia , Zhang Jinxiao , Li Qiang , Xing Xianran , Kuang Xiaojun 
Published: October 2024

DFT-based 11B NMR aided by 3D cRED method identified multiple 11B NMR signals for complex (BO)n anions and phase formation in Zn-doped YBO3, giving new insights into the local structure and phase-property modulation of inorganic functional materials.
Inkjet‐printed capacitively loaded Marchand baluns with enhanced fractional bandwidths
Authors: Steele Joe , Psychogiou Dimitra 
Published: October 2024

AbstractA comprehensive design methodology for the realization of ultra‐wideband and highly miniaturized capacitively loaded Marchand baluns (MBs), suitable for integration into balanced antenna systems is presented. A design technique to maximize the fractional bandwidth (FBW) for a given manufacturing process is demonstrated for the first time. Furthermore, a novel MB integration scheme using broadside‐coupled lines and 3D vertically integrated capacitors in a two‐material inkjet printing process is uniquely proposed. The concept has been experimentally validated within the S and C bands. It exhibits a footprint of 0.128 × 0.098 λg2, centre frequency of 4.4 GHz, and FBW of 121%. Its power loss, phase imbalance and amplitude imbalance were measured between 0.8 and 2.2 dB, 3 ± 2°, and 0.4 ± 0.4 dB, respectively.
Serial resonant converter (SRC) polynomial model implemented in a digital signal controller (DSC)
Authors: Díaz Gonzalez Juan , Rwamurangwa Evode , Villegas Saiz Pedro Jose , Martin‐Ramos Juan Antonio , Pernia Alberto Martin , Busto María G. 
Published: October 2024

AbstractThis work describes the process of modelling resonant converters by means of polynomial equations, in such a way that they can be easily implemented in digital controllers as digital signal controller. As an example, the serial resonant converter is modelled and its implementation in the TMS320F28335 Texas Controller.
Secondary halo bias through cosmic time
Authors: Balaguera-Antolínez Andrés , Montero-Dorta Antonio D. 
Published: October 2024

Context. When constructing mock galaxy catalogs based on suites of dark matter halo catalogs generated with approximated, calibrated, or machine-learning approaches, assigning intrinsic properties for these tracers is a step of paramount importance, given that they can shape the abundance and spatial distribution of mock galaxies and galaxy clusters.
Aims. We explore the possibility of assigning properties of dark matter halos within the context of calibrated or learning approaches, explicitly using clustering information. The goal is to retrieve the correct signal of primary and secondary large-scale effective bias as a function of properties reconstructed solely based on phase-space properties of the halo distribution and dark matter density field.
Methods. The algorithm reconstructs a set of halo properties (such as virial mass, maximum circular velocity, concentration, and spin) constrained to reproduce both primary and secondary (or assembly) bias. The key ingredients of the algorithm are the implementation of individually-assigned large-scale effective bias, a multi-scale approach to account for halo exclusion, and a hierarchical assignment of halo properties.
Results. The method facilitates the assignment of halo properties, aiming to replicate the large-scale effective bias, both primary and secondary. This constitutes an improvement over previous methods in the literature, especially for the high-mass end population.
Conclusions. We have designed a strategy for reconstructing the main properties of dark matter halos obtained using calibrated or learning algorithms, such that the one- and two-point statistics (on large scales) replicate the signal from detailed N-body simulations. We encourage the application of this strategy (or the implementation of our algorithm) for the generation of mock catalogs of dark matter halos based on approximated methods.
Retraction Note: A Post-Evaluation Method for Integrated Energy Systems Based on Triangular Whitening Weight Function
Authors: Wang Yongli , Teng Yue , Zhou Hanzhi , Dou Zhenlan , Zhang Chunyan , Sun Pei 
Published: October 2024

The authors have expressed the wish to retract this article on the ground that there are
some technical issues that require to be corrected.
1. The indicator does not provide a specific quantification method.
2. The indicator weight is obtained through subjective evaluation where there is a
significant deviation between the actual project verification and the current
comprehensive energy system operation results.
3. The post evaluation index values in the article are only obtained based on the average
value obtained from expert scoring, and the fitting results do not have reference
significance.
The Publisher and Editor(s) approved to the retraction.
Betrachtung der Wahrnehmung der Hilfsmittelnutzung und -versorgung im
Spannungsfeld der Entwicklung im Kindes- und Jugendalter und Symptomprogredienz
bei Betroffenen mit hereditärer Ataxie
Authors: Liebich Annika , Hentzgen Leonie , Nadke Marion , Heise Kirstin-Friederike 
Published: October 2024

Zusammenfassung
Ziel Hilfsmittel haben eine große Bedeutung in der Neuropädiatrie, jedoch
ist die Datenbasis zur selbsteingeschätzten Hilfsmittelnutzung und -versorgung
bei Betroffenen mit hereditärer Ataxie gering. Ziel der vorliegenden Arbeit ist
es daher, die individuelle Perspektive von Betroffenen auf die
Hilfsmittelnutzung und -versorgung zu untersuchen und diese im Spannungsfeld der
physiologischen und psychosozialen Entwicklung sowie der Symptomprogredienz zu
diskutieren.
Methodik Das Forschungsprojekt fand in Kooperation mit der Deutschen
Heredo-Ataxie-Gesellschaft e.V. im Sinne des Ansatzes „Patienten als Partner in
der Wissenschaft“ statt. Die Daten wurden per Online-Fragebogen und
Fokusgruppenbefragungen erhoben und mittels gemischt methodischen Vorgehens
sowohl quantitativ als auch qualitativ analysiert.
Ergebnisse Auf der Basis der vorliegenden Stichprobe mit Betroffenen aus
dem Jugend- und Erwachsenenbereich (n=47 Online-Fragebogen, n=6
Fokusgruppenbefragung) zeigt sich eine grundsätzlich positive Einschätzung der
Hilfsmittelnutzung. Im Kontrast dazu steht die individuelle Wahrnehmung des
Hilfsmittelversorgungsprozesses, bei dem vier wesentliche Problemfelder
identifiziert werden, die teilweise auf andere Krankheitsbilder übertragbar
sind, sich aber im Kinder- und Jugendbereich und durch die Seltenheit der
hereditären Ataxie verstärken. Zum einen besteht ein Spannungsfeld, dass sich
gerade in der Pädiatrie aus dem langwierigen Prozess bis der Diagnosestellung
und der damit verbundenen Lücke in der Indikation für ein Hilfsmittel während
der Erstversorgung ergibt. Zum anderen unterscheidet sich der Hilfsmittelbedarf
in der Pädiatrie vom Erwachsenenbereich und gerade bei den Hilfsmitteln, die
altersspezifisch zum Einsatz kommen fehlt häufig die Evidenz, die eine
Verordnung rechtfertigen würde.
Schlussfolgerung Neben der Notwendigkeit der Verbesserung des
Versorgungsprozesses, besteht bei Kindern und Jugendlichen mit seltenen
Erkrankungen, die von einer Symptomprogredienz gekennzeichnet sind, wesentliche
Lücken im Kenntnisstand bezüglich des Zusammenhangs zwischen Selbstbewusstsein
und Krankheitsverarbeitung einerseits und der Akzeptanz von Hilfsmitteln
andererseits. Darüber hinaus zeigt sich eine dringende Notwendigkeit zur
Verbesserung der Evidenzbasis für spezifische Hilfsmitteln insbesondere in ihrer
Bedeutung für die Selbstständigkeitsförderung entsprechend des jeweiligen Alters
und der jeweiligen Entwicklungsphase.
Effect of load-resisting force on photoisomerization mechanism of a single second generation light-driven molecular rotary motor
Authors: Pang Xiaojuan , Zhao Kaiyue , Hu Deping , Zhong Quanjie , Zhang Ningbo , Jiang Chenwei 
Published: October 2024

A pivotal aspect of molecular motors is their capability to generate load capacity from a single entity. However, few studies have directly characterized the load-resisting force of a single light-driven molecular motor. This research provides a simulation analysis of the load-resisting force for a highly efficient, second-generation molecular motor developed by Feringa et al. We investigate the M-to-P photoinduced nonadiabatic molecular dynamics of 9-(2,3-dihydro-2-methyl-1H-benz[e]inden-1-ylidene)-9H-fluorene utilizing Tully’s surface hopping method at the semi-empirical OM2/MRCI level under varying load-resisting forces. The findings indicate that the quantum yield remains relatively stable under forces up to 0.003 a.u., with the photoisomerization mechanism functioning typically. Beyond this threshold, the quantum yield declines, and an alternative photoisomerization mechanism emerges, characterized by an inversion of the central double bond’s twisting direction. The photoisomerization process stalls when the force attains a critical value of 0.012 a.u. Moreover, the average lifetime of the excited state oscillates around that of the unperturbed system. The quantum yield and mean lifetime of the S1 excited state in the absence of external force are recorded at 0.54 and 877.9 fs, respectively. In addition, we analyze a time-dependent fluorescence radiation spectrum, confirming the presence of a dark state and significant vibrations, as previously observed experimentally by Conyard et al.
The effects of thumb position on backhand disc golf throws of a mid-range disc
Authors: Koch Noah , McGuire Hayden , Cole Connor , Lindsey Zachary 
Published: October 2024

In disc golf, having a comfortable and proper grip on the disc is crucial to achieving optimal throw dynamics, and the placement of the thumb is a key component of the grip. This research investigated the relationship between thumb position on a mid-range disc and the resulting angular speed, translational speed, and torque generated during the throw. Using a Discraft Buzzz disc equipped with a TechDisc sensor, measurements were obtained for throws made using five different thumb positions, starting near the outer edge of the disc (p = 1) and ending near the center of the disc (p = 5). Participants were sorted into two skill level groups that were determined based on their Professional Disc Golf Association rating. Each participant performed five throws at each thumb position with maximum effort, and angular and translational speeds of each throw were measured. The results varied between skill groups, but collective data displayed a general linear correlation between angular and translational speeds achieved across all thumb positions. While angular speed and applied torque were observed to be maximum for the thumb position with the largest radial distance from the center of the disc (p = 1), thumb positions located ∼3–5 cm radially inward from the outer edge (p = 2 and p = 3) resulted in the highest translational speeds. In general, a universally favorable thumb position was determined as that resulting in simultaneously large values of both angular and translational speeds for all participants, which occurred closest to the p = 2 position (∼3 cm from the outer edge).
The model of the local Universe in the framework of the second-order perturbation theory
Authors: Sikora Szymon , Ostrowski Jan J 
Published: October 2024

Abstract
Recently, we constructed the specific solution to the second-order cosmological perturbation theory, around any Friedmann–Lemaître–Robertson–Walker background filled with dust matter and a positive cosmological constant. In this paper, we use the Cosmicflows-4 sample of galaxies from the Extragalactic Distance Database to constrain this metric tensor. We obtain an approximation to the local matter distribution and geometry. We numerically solve for null geodesics for randomly distributed mock sources and compare this model with the Lemaître–Hubble constant inferred from the observations under the assumption of perfect isotropy and homogeneity. We conclude on effects of realistic inhomogeneities on the luminosity distance in the context of the Hubble tension and discuss limitations of our approach.
Dynamical friction in rotating ultralight dark matter galactic cores
Authors: Gorkavenko V M , Barabash O V , Gorkavenko T V , Teslyk O M , Zaporozhchenko A O , Jia Junji , Yakimenko A I , Gorbar E V 
Published: October 2024

Abstract
Dynamical friction and stellar orbital motion in spiral galaxies with dark matter composed of ultralight bosons in the state of rotating Bose–Einstein condensate (BEC) are studied. It is found that the dynamical friction force is significantly affected by the topological charge of the vortex structure of the BEC core with the strongest effect at distances near the galactic center. It is also shown that the ultralight dark matter self-interaction plays an important role in studying the dynamical friction.
A liquid crystal device-based apparatus for observing optical vortex and manipulating micro-particles
Authors: Zheng Zhi-Gang , Luo Duan-Bin , Shen Dong , Wang Xiao-Qian 
Published: October 2024

Abstract
In this paper, we disclose a self-developed liquid crystal device-based optical apparatus for undergraduate teaching experiments. Three relevant experiments have been presented through the experiment-based class: the undergraduates learned about light-matter interaction, the photo-patterning of a liquid crystal q-plate and the generation of an optical vortex, and the manipulation of micro-particles via angular momentum. Most undergraduates held positive remarks on the optical apparatus and were satisfied with the assigned tasks in the experiment. Indeed, our proposed optical apparatus is not only applicable to the explorative research work but also suitable for the undergraduates’ teaching laboratories.
A uniqueness theory on determining the nonlinear energy potential in phase-field system
Authors: Ni Tianhao , Lai Jun 
Published: October 2024

Abstract
The phase-field system is a nonlinear model that has significant applications in material sciences. In this paper, we are concerned with the uniqueness of determining the nonlinear energy potential in a phase-field system consisting of Cahn–Hilliard and Allen–Cahn equations. This system finds widespread applications in the development of alloys engineered to withstand extreme temperatures and pressures. The goal is to reconstruct the nonlinear energy potential through the measurements of concentration fields. We establish the local well-posedness of the phase-field system based on the implicit function theorem in Banach spaces. Both of the uniqueness results for recovering time-independent and time-dependent energy potential functions are provided through the higher order linearization technique.
Rydberg atom-based microwave electrometry using polarization spectroscopy
Authors: Duarte Gomes Naomy , Marrara Pepino Vinicius , Viana Borges Ben-Hur , Varela Magalhães Daniel , de Jesus Napolitano Reginaldo , Alejandro Lefrán Torres Manuel , Douglas Massayuki Kondo Jorge , Gustavo Marcassa Luis 
Published: October 2024

Abstract
In this study, we investigated Rydberg atom-based microwave (MW) electrometry using polarization spectroscopy in a room-temperature vapor cell. By measuring Autler-Townes splitting in the electromagnetically induced transparency (EIT) spectrum, we determined that the minimum measurable MW electric field is approximately five times lower than conventional EIT techniques. The results are well reproduced by a full optical Bloch equation model, which takes into account all the hyperfine levels involved. Subsequently, the EIT setup was used to characterize a custom MW cylindrical lens, which increases the field at the focus by a factor of three, decreasing the minimum measurable MW electric field by the same amount. Our results indicate that the combination of polarization spectroscopy and a MW lens may enhance MW electrometry, and may allow its use as a secondary standard.
Photoelectron momentum distribution in structured strong fields
Authors: Sinha Abhisek , Sen Arnab , Sen Sanket , Sharma Vandana , Gopal Ram 
Published: October 2024

Abstract
In this study, a reaction microscope is used to explore the behavior of electrons in shaped beams under strong field conditions. Photoelectron momentum spectra indicate that the inclusion of orbital angular momentum (OAM) of light does not significantly impact the available electron angular momentum states. However, the distinctive donut shape of the beam plays a crucial role in determining the observed Photoelectron Angular Distributions (PADs). TDSE simulations, incorporating focal volume averaging indicates that the geometric properties of the focal region of the OAM and the Gaussian beams affect the photoelectron spectra differently. By averaging the spectra across different intensity regions, we have provided a qualitative explanation for the variations in photoelectron spectra resulting from the shapes of the individual beams. This result shows that the transfer of OAM in ultrashort light pulses cannot be detected in gas ensembles due to the ionization being overwhelmed by atoms in the most intense region with minimal spatial phase variation within the laser field. We demonstrate that the differences in the momentum spectra arising from shaped beams can be qualitatively explained using models that incorporate the spatial averaging of the beam, rather than focusing on the OAM content.