bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les énoncés averbaux : de l’identification à l’évaluation
Authors: Guillemin-Flescher Jacqueline 
Published: November 2017

Résumé Cette étude a un double objectif : à la fois théorique et contrastif. Sur le plan théorique, il s’agit de proposer une explication des énoncés averbaux en termes d’opération qualitative. Celle-ci se ramène à deux variables : soit on identifie le prédicat, soit on l’évalue. Le deuxième objectif consiste à dégager les conditions sous lesquelles ces énoncés apparaissent selon les langues. Les exemples sont relevés dans un corpus bilingue anglais / français dans la mesure où les traductions s’avèrent systématisables. Bien que la même opération soit en jeu quelle que soit la langue, la comparaison des textes originaux et de leurs traductions permet de déterminer les contraintes qui conditionnent les choix récurrents des traducteurs.
Essential Role of CARD14 in Murine Experimental Psoriasis
Authors: Tanaka Mayuri , Kobiyama Kouji , Honda Tetsuya , Uchio-Yamada Kozue , Natsume-Kitatani Yayoi , Mizuguchi Kenji , Kabashima Kenji , Ishii Ken J. 
Published: November 2017

Abstract
Caspase recruitment domain family member 14 (CARD14) was recently identified as a psoriasis-susceptibility gene, but its immunological role in the pathogenesis of psoriasis in vivo remains unclear. In this study, we examined the role of CARD14 in murine experimental models of psoriasis induced by either imiquimod (IMQ) cream or recombinant IL-23 injection. In all models tested, the psoriasiform skin inflammation was abrogated in Card14−/− mice. Comparison of the early gene signature of the skin between IMQ-cream–treated Card14−/− mice and Tlr7−/−Tlr9−/− mice revealed not only their similarity, but also distinct gene sets targeted by IL-23. Cell type–specific analysis of these mice identified skin Langerinhigh Langerhans cells as a potent producer of IL-23, which was dependent on both TLR7 and TLR9 but independent of CARD14, suggesting that CARD14 is acting downstream of IL-23, not TLR7 or TLR9. Instead, a bone marrow chimera study suggested that CARD14 in radio-sensitive hematopoietic cells was required for IMQ-induced psoriasiform skin inflammation, controlling the number of Vγ4+ T cells producing IL-17 or IL-22 infiltrating through the dermis to the inflamed epidermis. These data indicate that CARD14 is essential and a potential therapeutic target for psoriasis.
Alimentation minérale et urolithiases félines
Authors: Wolter Roger Michel 
Published: November 2017

L’urolithiase à phosphates ammoniacomagnésiens (struvite) a représenté dans le passé plus de 90% de l’ensemble des urolithiases félines. Aujourd’hui, elle est beaucoup mieux prévenue et même traitée par voie alimentaire, en augmentant le taux de sel, en limitant la teneur magnésique, surtout en acidifiant les urines par l’apport renforcé d’anions.
Toutefois, on constate à l’inverse une forte progression de l’urolithiase à oxalate de calcium qui tendrait à devenir majoritaire. Il semblerait donc qu’une manipulation trop simpliste et trop brutale de l’équilibre alimentaire fasse tomber d’un écueil dans l’autre, vérifiant la loi du juste milieu.
Répression du génome de l’embryon : comment, pourquoi ?
Authors: Delouis Claude , Forlani Sylvie , Jule Sophia 
Published: November 2017

L’expression du génome de l’embryon a été étudiée en utilisant des lapins dont la lignée germinale a été enrichie avec un gène marqueur associé au promoteur du gène tk du virus de l’herpès, et à des séquences régulatrices dérivées d’introns et d’exons du gène humain hprt et de la séquence F101 du polyome. Cette construction, nommée IIPytl2LacZ, s’exprime dans les cellules de l’embryon transgénique collecté au stade une cellule et maintenu en culture.
Lorsqu’il est d’origine paternelle, le transgène ne s’exprime in vitro qu’à partir du stade 8 cellules alors que d’origine maternelle il s’exprime à partir du stade 16 cellules. Ainsi, in vitro, l’expression du génome est réprimée pendant les premiers stades de développement de l’embryon de lapin. La répression du génome d’origine maternelle a une durée plus longue que celle du génome d’origine paternelle ; la différence correspond au temps nécessaire à la réalisation un cycle cellulaire supplémentaire.
La présence d’aphidicoline, un inhibiteur de synthèse de l’ADN, dès le début de la culture s’oppose au passage de l’embryon du stade 2 au stade 4 cellules. Dans ces conditions, le transgène n’est plus exprimé quelle que soit l’origine germinale du gène. L’addition plus tardive de l’aphidicoline dans le milieu de culture, qui permet d’arrêter le développement de l’embryon au stade 4 cellules, réduit encore significativement l’expression du génome d’origine paternelle ou maternelle. Ces résultats montrent que la transcription devient possible seulement après la réalisation des phases de synthèse de l’ADN, ce qui suggère qu’une réoganisation fonctionnelle du génome de l’embryon est nécessaire pour la levée de la répression de la transcription.
Eugenia bandeirista: o melhoramento da raça brasileira como falso propósito de saúde pública
Authors: Coelho George Leonardo Seabra 
Published: November 2017

Neste artigo avaliaremos como os temas da Saúde Pública e da eugenia são apropriados pelo Movimento Bandeira e divulgado pela revista S. Paulo e pelo jornal Anhanguera. Não consideramos que esses temas sejam exclusivos do ideário bandeirista, visto que, esse debate já estava posto pelos higienistas e eugenistas no início do século XX, assim como, já havia sido tratado pela escrita literária de Monteiro Lobato. Mesmo que a relação entre Saúde Pública e eugenia não seja inaugurada com o ideário bandeirista, esse grupo ainda não estudado pela historiografia brasileira apresentou uma forma peculiar de abordar o tema da Saúde Pública e da eugenia. Nesse sentido, demonstraremos como o ideário deste grupo se colocou na arena política da década de trinta como mais uma proposta autoritária de remodelação da Nação.
ANÁLISE DA TRANSFERÊNCIA DE CONHECIMENTOS ADQUIRIDOS EM UM PROGRAMA DE TREINAMENTO EM ALVENARIA ESTRUTURAL
Authors: Bressiani Lucia , Oliveira Ana Maria de Sousa Santana de , Oliveira Ricardo Rocha de 
Published: November 2017

RESUMO: A transferência de aprendizagem é um dos processos de maior interesse nos modelos de avaliação de treinamento. Muitos trabalhos buscam investigar após o treinamento, quais eventos do ambiente de trabalho influenciam na eficácia do programa, contribuindo para a transferência de conhecimentos. Desta forma, este trabalho busca efetuar uma análise da transferência dos conhecimentos, após a realização de um treinamento em uma obra em alvenaria estrutural. O objetivo é verificar quais fatores afetam de forma positiva ou negativa na transferência de conhecimentos. Para o trabalho foi utilizado um modelo de avaliação de transferência já testado e validado por outros pesquisadores. O modelo foi aplicado para os funcionários envolvidos com o processo de execução das paredes em alvenaria estrutural em uma obra na cidade de Toledo, PR. Com isso, procura-se contribuir para a melhoria dos processos de treinamentos no setor da construção civil, de forma a se obter os melhores resultados em termos de desempenho no trabalho.ABSTRACT: The transfer of learning is one of the processes of greatest interest in models of training evaluation. Many studies seek to investigate after training, what events influence the effectiveness of the program, contributing to the transfer of knowledge. Thus, this work aims to make an analysis of the transfer of knowledge, after the completion of training in a work in masonry. The goal is to determine which factors affect positively or negatively the transfer of knowledge. For the study we used a transfer valuation model already tried and tested by other researchers. The model was applied to the staff involved in the implementation process of the walls in masonry in a work in the city of Toledo, PR. It seeks to contribute to the improvement of training processes in the construction sector in order to obtain the best results in terms of job performance.
Incidence and quantitative analysis of dissociated optic nerve fiber layer appearance: real loss of retinal nerve fiber layer?
Authors: Kim Yoon J. , Lee Kyoung S. , Joe Soo G. , Kim June-Gone 
Published: November 2017

Purpose: To assess the association between appearance of dissociated optic nerve fiber layer (DONFL) after internal limiting membrane (ILM) peeling and changes in the macular nerve fiber layer (NFL) area by spectral-domain optical coherence tomography (SD-OCT). Methods: This study included 132 consecutive patients who had successfully undergone vitrectomy with ILM peeling for idiopathic epiretinal membrane or macular holes and had been followed up for ≥6 months. Two examiners evaluated macular 5-line raster horizontal SD-OCT images and categorized the patients on the basis of presence (group I) or absence (group II) of DONFL. The average macular NFL areas in both groups were measured using ImageJ at baseline and 1, 3, and 6 months after surgery. Results: Among the 132 eyes of 132 patients, DONFL was noted in 42 (31.8%), 104 (78.8%), 106 (80.3%), and 106 (80.3%) eyes at 1, 3, and 6 months and at the last visit (12.8 ± 6.5 months) after surgery. These layers appeared most commonly between 1 and 3 months after ILM peeling. There was no significant difference in average macular NFL area between groups I and II (3453.4 ± 125.3 and 3513.0 ± 100.2 pixels, respectively) at 6 months after surgery (p = 0.56). Conclusions: Appearance of DONFL increased between postoperative months 1 and 3. Moreover, there was no significant difference in average NFL in terms of DONFL. Thus, appearance of DONFL might represent macular NFL rearrangement and reorganization rather than true mechanical damage to the NFL after ILM peeling.
Blindness and visual impairment in opera
Authors: Aydin Pinar , Ritch Robert , O’Dwyer John 
Published: November 2017

Purpose: The performing arts mirror the human condition. This study sought to analyze the reasons for inclusion of visually impaired characters in opera, the cause of the blindness or near blindness, and the dramatic purpose of the blindness in the storyline. Methods: We reviewed operas from the 18th century to 2010 and included all characters with ocular problems. We classified the cause of each character’s ocular problem (organic, nonorganic, and other) in relation to the thematic setting of the opera: biblical and mythical, blind beggars or blind musicians, historical (real or fictional characters), and contemporary or futuristic. Results: Cases of blindness in 55 characters (2 as a choir) from 38 operas were detected over 3 centuries of repertoire: 11 had trauma-related visual impairment, 5 had congenital blindness, 18 had visual impairment of unknown cause, 9 had psychogenic or malingering blindness, and 12 were symbolic or miracle-related. One opera featured an ophthalmologist curing a patient. Conclusions: The research illustrates that visual impairment was frequently used as an artistic device to enhance the intent and situate an opera in its time.
An unusual case of bilateral pigmented maculopathy and anterior segment dysgenesis
Authors: Bloch Edward , Pefkianaki Maria , Hakim Jamil 
Published: November 2017

Purpose: Pigmentary maculopathy can occur in the context of various inherited and acquired diseases. Anterior segment dysgenesis arises due to developmental anomalies and may be associated with systemic disease, as in Rieger syndrome. Case report: A 49-year-old woman presented with longstanding reduction in vision, evidence of anterior segment dysgenesis, and multiple discrete pigmented lesions throughout the macula bilaterally. Electroretinographic findings were consistent with severe macular dysfunction. Gene array analysis did not reveal any chromosomal imbalances or other specific abnormalities. Conclusions: This is a unique case of bilateral pigmentary maculopathy and anterior segment dysgenesis, with clinical findings that are not characteristic of previously reported disease.
Blue Planet dialysis: novel water-sparing strategies for reducing dialysate flow
Authors: Molano-Triviño Alejandra , Wancjer Benjamin , Neri Mauro M. , Karopadi Akash N. , Rosner Mitchell , Ronco Claudio 
Published: November 2017

Introduction: Hemodialysis (HD) is an expensive therapy in economic and in ecological terms, owing to a high carbon footprint and significant consumption of natural sources, especially water. Our aim was to review strategies to diminish waste of water in maintenance dialysis, exploring previously described water reuse trends and less known strategies for reducing the dialysate flow. Methods: We conducted a systematic review of water-sparing strategies, including the reuse of reverse osmosis rejected water and the reduction of dialysate flux. We performed a search in Medline, Pubmed, Scielo, OVID and Biblioteca Redentor, using key words: Dialysate flow rate, Dialysate flux, and decrease; excluding: online, peritoneal, continuous, blood access, needle, hemodiafiltration, acute, pharmacokinetics, increase. We limited our search to adult humans or in vitro trials in English, Spanish, Italian and Portuguese, between January 1980 and June 2017. We found 816 trials. 37 articles were retrieved for review, and 11 articles were analyzed. Results and conclusions: Conservation of water in chronic HD should be considered an important responsibility of healthcare practitioners all over the world. We present a wider usage of dialysate flow rates, considering that it would lead to significant water conservation without much compromise on dialysis efficacy in small patients. We believe that further investigation into the utility of reduced dialysate flux in different populations is needed to broaden our understanding of how we can use these techniques in order to significantly reduce water consumption during chronic HD while still ensuring optimum efficacy and efficiency of the therapy.
Printability of papers recycled from toner and inkjet-printed papers after deinking and recycling processes
Authors: Karademir Arif , Aydemir Cem , Tutak Dogan , Aravamuthan Raja 
Published: November 2017

Background: In our contemporary world, while part of the fibers used in the paper industry is obtained from primary fibers such as wood and agricultural plants, the rest is obtained from secondary fibers from waste papers. To manufacture paper with high optical quality from fibers of recycled waste papers, these papers require deinking and bleaching of fibers at desired levels. High efficiency in removal of ink from paper mass during recycling, and hence deinkability, are especially crucial for the optical and printability quality of the ultimate manufactured paper. Methods: In the present study, deinkability and printability performance of digitally printed paper with toner or inkjet ink were compared for the postrecycling product. To that end, opaque 80 g/m2 office paper was digitally printed under standard printing conditions with laser toner or inkjet ink; then these sheets of paper were deinked by a deinking process based on the INGEDE method 11 p. After the deinking operation, the optical properties of the obtained recycled handsheets were compared with unprinted (reference) paper. Then the recycled paper was printed on once again under the same conditions as before with inkjet and laser printers, to monitor and measure printing color change before and after recycling, and differences in color universe. Results: Recycling and printing performances of water-based inkjet and toner-based laser printed paper were obtained. The outcomes for laser-printed recycled paper were better than those for inkjet-printed recycled paper. Conclusions: Compared for luminosity Y, brightness, CIE a* and CIE b* values, paper recycled from laser-printed paper exhibited higher value than paper recycled from inkjet-printed paper.
Targeting zero catheter-related bloodstream infections in pediatric intensive care unit: a retrospective matched case-control study
Authors: Biasucci Daniele G. , Pittiruti Mauro , Taddei Alessandra , Picconi Enzo , Pizza Alessandro , Celentano Davide , Piastra Marco , Scoppettuolo Giancarlo , Conti Giorgio 
Published: November 2017

Introduction: The aim of this study was to evaluate the effectiveness and safety of a new three-component ‘bundle’ for insertion and management of centrally inserted central catheters (CICCs), designed to minimize catheter-related bloodstream infections (CRBSIs) in critically ill children. Methods: Our ‘bundle’ has three components: insertion, management, and education. Insertion and management recommendations include: skin antisepsis with 2% chlorhexidine; maximal barrier precautions; ultrasound-guided venipuncture; tunneling of the catheter when a long indwelling time is expected; glue on the exit site; sutureless securement; use of transparent dressing; chlorhexidine sponge dressing on the 7th day; neutral displacement needle-free connectors. All CICCs were inserted by appropriately trained physicians proficient in a standardized simulation training program. Results: We compared CRBSI rate per 1000 catheters-days of CICCs inserted before adoption of our new bundle with that of CICCs inserted after implementation of the bundle. CICCs inserted after adoption of the bundle remained in place for a mean of 2.2 days longer than those inserted before. We found a drop in CRBSI rate to 10%, from 15 per 1000 catheters-days to 1.5. Conclusions: Our data suggest that a bundle aimed at minimizing CR-BSI in critically ill children should incorporate four practices: (1) ultrasound guidance, which minimizes contamination by reducing the number of attempts and possible break-down of aseptic technique; (2) tunneling the catheter to obtain exit site in the infra-clavicular area with reduced bacterial colonization; (3) glue, which seals and protects the exit site; (4) simulation-based education of the staff.
How to treat arteriovenous graft infection: total versus partial graft excision
Authors: Min Kim Suh , Min Seung-Kee , Ahn Sanghyun , Min Sang-Il , Ha Jongwon , Chung Jung Kee 
Published: November 2017

Introduction: Arteriovenous graft (AVG) infection can result in life-threatening sepsis and loss of vascular access. A retrospective study was performed to establish an appropriate treatment strategy for AVG infection. Methods: A total of 50 cases of AVG infection were treated between January 2005 and June 2016. The surgical methods used were total graft excision (TGE) (n = 34), or partial graft excision (PGE) with interposition graft (n = 16). Results: Infection was noted at a puncture site (n = 22), a prior incision for surgery or endovascular therapy (n = 20), and abandoned (currently unused) grafts (n = 5). Infection occurred within 1 month after AVG creation (n = 1), or any intervention (n = 14), and more than 1 month after creation or intervention (n = 35). Simultaneous remote infection was identified in 7 patients, 2 of whom underwent an operation for infective endocarditis and spondylitis. After PGE, 5 patients (5/16, 31.2%) having recurrent infection were treated with further graft excision; however, no patient showed life-threatening complications. After TGE, a central venous catheter (CVC) was inserted and used for a median period of 90 days. Among 34 patients who underwent TGE, new vascular access was created in 18 patients at a median period of 2 months later, and 12 patients continued to use a CVC until last follow-up or death. Conclusions: PGE could be a treatment option for AVG infection to achieve both infection eradication and vascular access preservation in selected patients. Because of a higher risk of recurrent infection, sufficient surgical removal and careful postoperative management are warranted.
Intraspinal Mesenchymal Chondrosarcoma: Report of a Pediatric Case and Literature Review
Authors: Di Giannatale Angela , Colletti Marta , Russo Ida , Ferruzzi Valentina , Anna Vito Andrea Dell , Cozza Raffaele , Colafati Giovanna Stefania , Messina Raffaella , Mastronuzzi Angela , De Vito Rita , Milano Giuseppe Maria 
Published: November 2017

Purpose Mesenchymal chondrosarcoma (MCS) is an aggressive variant of chondrosarcoma and is a rare tumor, particularly within the pediatric population. Commonly, MCS originates in the bone, but it can also arise in extraskeletal sites, such as the brain and the intraspinal area. Due to the rarity of this tumor, there are no guidelines for its optimal treatment. Methods We report a case of intradural extra medullary MCS, located at the T11–T12 level, in a 14-year-old male. The tumor was documented by magnetic resonance imaging and treated with gross total resection (GTR) without adjuvant treatment. We further reviewed the relevant pediatric literature and discussed the management and outcome of intracranial and intraspinal MCS. Results The patient's follow-up showed no evidence of disease 2 years from diagnosis. A total of 51 cases of intracranial and intraspinal MCS have been reported (24 intraspinal and 27 intracranial). Recurrence has been described in only 4 patients with intraspinal MSC, and among them 3 received adjuvant chemotherapy and radiotherapy. GTR seems to reduce the risk of recurrence and, due to a higher cancer-mortality rate for these patients, adjuvant chemotherapy and radiotherapy are recommended in case aggressive surgery is not possible. Conclusions According to our single experience, we would suggest that adjuvant therapy might be unnecessary in cases where a localized MCS undergoes GTR. Chemotherapy and radiotherapy should be recommended when GTR cannot be obtained. Further studies are needed to investigate a standard treatment approach for this rare tumor.
ФОКУС НА ЗАДОВОЉСТВО КОРИСНИКА У ИНТЕГРИСАНОМ МЕНАЏМЕНТУ КРОЗ ПРИМЈЕНУ БСЦ КОНЦЕПТА У ГРАДСКОЈ УПРАВИ БАЊА ЛУКА // CUSTOMER SATISFACTION FOCUS IN INTEGRATED MANAGEMENT APPLIED THROUGH BSC CONCEPT IN ADMINISTRATIVE SERVICE IN LOCAL GOVERNMENT OF BANJA LUKA
Authors: Бобрек Мацановић Кристина 
Published: November 2017

Задовољан корисник је основни приоритет како профитно оријентисанихкомпанија, тако и непрофиних организација или појединаца који се баве билокаквом испоруком производа или услуга. Глобални процеси у европској исвјетској економији афирмишу поступке мјерења задовољства корисника ипримјену многих метода менаџмента у вођењу организација према његовомсталном расту. Међутим, често у пракси није лако направити мост између визијекоју има главни менаџмент, преко оперативних циљева и стратегије којуспроводи оперативни менаџмент, па до запослених који су у свакодневномконтакту са корисником. У овом смислу значајну помоћ менаџментуорганизација пружају процеси стандардизације менаџмента који истовременопредстављају својеврсне облике глобализације на свјетском (ИСО стандарди) иевропском (ЕН норме) простору. Ови стандарди афирмишу примјенумногобројних метода и алата менаџмента који помажу организацијама далокална ограничења претварају у глобалне предности. Један од концепата којије веома успјешан управо у овој конкретизацији циљева и мјерењу њиховогостваривања је BSC - Balanced scorecard. Због тога је и циљ овог рада да покажепримјену концепта Balanced scorecard, у оквиру интегрисаног система менаџмента, са посебним акцентом на задовољство корисника. Конкретанпримјер ће бити приказан кроз BSC карту Градске управе Бањалука.