bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between paraoxonase 1 (PON1) enzyme activity, PON1 C(−107)T polymorphism, nutritional status, and lipid profile in children
Authors: Uliano Gabriela , Muniz Ludmila C. , Barros Carlos C. , Schneider Augusto , Valle Sandra C. 
Published: December 2016

Abstract
Background
Paraoxonase 1 (PON1) is an enzyme that possesses anti-atherogenic and anti-inflammatory properties with serum levels determined by genetic and exogenous factors. Lower serum PON1 arylesterase activity is associated to metabolic alterations related to childhood overweight and onset and/or development of diabetes and CVD later in life. However, data on the relationship between genetic PON1 polymorphisms and nutritional status as well as lipid profile in children are limited.
To investigate the distribution of the C(−107)T PON1 gene polymorphism and its relation with serum PON1 enzyme activity, nutritional status and lipid profile in children.

Methods
A cross-sectional study was performed including 73 children aged 5 to 7 years who attended public pediatric clinics. PON1 C(−107)T, arylesterase activity, body mass index for the age, and serum lipid profile were evaluated.

Results
PON1 activity was higher in overweight children compared to the normal weight ones (p = 0.02). The genotypic frequency did not differ between the two groups (p > 0.05). Carriers of CC genotype had higher enzyme activity than T allele carriers, and this difference was greater among normal weight children. HDL levels were higher among normal weight children carrying CC genotype, compared to those carrying the T allele (p < 0.01).

Conclusion
The PON1 C(−107)T polymorphism is associated with higher serum enzyme activity in children, as observed previously in adults. In addition, this polymorphism also shows association to higher high density lipoprotein (HDL) levels and serum PON1 arylesterase activity in the normal weight children studied.
Clinical observation of adverse drug reactions to non-ionic iodinated contrast media in population with underlying diseases and risk factors
Authors: Li Xue , Liu Heng , Zhao Li , Liu Junling , Cai Li , Liu Lei , Zhang Weiguo 
Published: December 2016

Objective:
To determine the adverse drug reaction (ADR) profile of non-ionic iodinated contrast media in populations with underlying diseases and risk factors and to provide guidance for more safe and rational use of iodinated contrast media (ICMs) in the clinic.

Methods:
Data from 120,822 cases who underwent enhanced CT examination in our hospital from January 2014 to March 2016 were collected. A standardized case report form was used for data collection and analysis.

Results:
The incidence of ADRs was 0.4% and 0.44% in patients with and without underlying diseases, respectively (p = 0.378). Risk factor analysis revealed that patients with asthma had the highest incidence of ADRs, followed by patients with cardiac insufficiency and patients who were aged had the lowest incidence. There was a low incidence of ADRs in patients under metformin (0.36%) and β-adrenaline receptor antagonist (0.20%) medication. The incidence was the highest in patients with previous ADRs to ICMs (7.17%) and the lowest in those with a history of ICM usage but no previous reactions (0.32%). ADRs were more common in patients at high risk at a higher injection dose (≥100 ml; p &lt; 0.01) and speed (≥5 ml s−1; p &lt; 0.01).

Conclusion:
The incidence of ADRs was extremely low in patients regardless of underlying diseases. Some high-risk factors have certain correlations with the occurrence of ADRs. Particular attention should be given to patients at high risk when performing enhanced CT examination.

Advances in knowledge:
The correlation between various risk factors and underlying diseases and ADRs was comprehensively analyzed in a large-scale population.
SPECIALISTS TRAINING IN QUALITY MANAGEMENT
Authors: Степанов  , Stepanov Anatoliy , Лаптева  , Lapteva Anna 
Published: December 2016

This article presents the analysis of State Educational Standards for the specialty and major &#34;Quality Management&#34;, prepared and brought into force by the Ministry of Education and Science of the Russian Federation in 2000-2015 years. The requirements for quality management specialists training, contained in these educational standards, knowledge, skills and competences required from graduates are compared with the requirements to quality specialists imposed by a modern market economy in Russia. As a result the authors suggest that instead of Bachelors of Applied Science the modern domestic companies need Engineer Quality Managers whose function is fundamentally different. According to the current educational standards the activity of a Bachelor in the company is limited to the maintenance of the quality management systems developed under ISO 9001. It is perfectly acceptable for a developed market economy where all the problems of increasing product marketability are solved within the quality management system. For emerging market economies a Bachelor degree is premature, as it is insufficient or not relevant to work only within the quality management system. Only an Engineer Manager, who for five years of study at the university has obtained knowledge relating to the different areas of company´s activity and mastered special methods and tools of quality management, can provide quality management required nowadays which is important for Russia´s emerging economy. The article also draws attention to the fact that under current conditions there is a need for state support of the quality activities and the implementation of &#34;Concept of National Policy in the Field of Products and Services Quality&#34;, developed and published back in 2009.
For this article the authors have used their own experience in quality assurance in construction and training of quality management specialists in BSTU named after V.G. Shukhov.
DESIGN OF QUALITY MANAGEMENT PROCESSES BASED ON QFD METHOD
Authors: Мирошников Вячеслав , Miroshnikov Vyacheslav , Борбаць Николай , Borbats Nikolay 
Published: December 2016

The creation and introduction of the efficient quality management system (QMS) is impossible without the management realization of its processes, one of key elements in which is designing. And upon that how well is a process designed will the efficiency depend both of the process itself and the whole of the system of interrelated processes a part of which it is. To in-crease the design efficiency of quality management processes the methodology of quality function defini-tion – QFD is offered for use. At the first stage of its realization in processes of quality management it is necessary to determine the demands made to the process under development. For that, in its turn, it is necessary to identify process outlets and basic users of its results. Because of the peculiarities in quality man-agement processes the demands to them should be compiled being guided mainly by corresponding regu-latory documentation regulating both processes outlets and methods of their carrying out.
The requirements revealed further with the aid of a matrix diagram are transformed into parameters subjected to the control in the course of a process ful-fillment. At the next stage for the most critical parame-ters of the process there are defined corresponding kinds of management which is also carried out on the basis of a matrix program. Finally, for the kinds of control revealed at the previous stage one selects methods and means of measurements and control which are most suitable to ensure the specified characteristics of reliability taking into account the requirements to economy and control-appropriateness.
The application of the procedure described is shown by the example of designing the input control process of paint-and-lacquer materials at an industrial enterprise.
MODELING OF GENERATING SURFACES IN FEMALE MILLING CUTTERS WITH DESIGN RADIAL INFEED FOR MACHINING SHAFTS WITH HOMAXONIC PROFILE
Authors: Разумов Михаил , Razumov Mikhail , Сидорова Марина , Sidorova Marina , Куц Вадим , Kuts Vadim , Мальнева Юлия , Malneva Yuliya 
Published: December 2016

The paper reports the solution of the urgent problem on technological solutions searches ensuring the shaping of profile keyless joints. The investigation was carried out with the use of the methodology of a structural-parametric synthesis of metalcutting systems which allowed compiling mathematical and geometrical models of a female milling cutter generating surface with a design radial feed for the shaping of profile keyless joints. On the basis of this there was carried out the analysis of cutting procedures chosen which has shown that the procedure with a coaxial location of a milling cutter regarding a shaft is most promising from the point of view of cost price and machining accuracy.
The research results may be used at the devel-opment of design-engineering documentation at the preparation of profile shafts production to ensure product characteristics specified.
Evaluation of white matter structure changes, as assessed in tractography, and cognitive dysfunctions in patients with early onset schizophrenia and their first-degree relatives
Authors: Gawłowska-Sawosz Marta , Pawełczyk Agnieszka , Gębski Piotr , Pawełczyk Tomasz , Strzelecki Dominik , Rabe-Jabłońska Jolanta 
Published: December 2016

Cel pracyCelem projektu była ocena różnic w strukturze włókien istoty białej, mierzonych miarą wartości anizotropii frakcyjnej (FA), pomiędzy grupą badaną chorych na schizofrenię o wczesnym początku (early onset schizophrenia, EOS), ich krewnych I stopnia i grupą kontrolną oraz niezależna ocena stopnia nasilenia zaburzeń pamięci operacyjnej w grupach.MetodaDo badania włączono 20 pacjentów z rozpoznaniem schizofrenii paranoidalnej, postawionej przed ukończeniem 18. r.ż., 20 – osobową grupę rodziców pacjentów, dobranych pod względem płci oraz 20 osób zdrowej kontroli. U wszystkich uczestników badania wykonano badanie traktograficzne (1,5T) oraz wybrane testy neuropsychologiczne, pozwalające na ocenę pamięci operacyjnej, pamięci bezpośredniej oraz koncentracji uwagi (testu TMT-A i TMT-B, test powtarzania cyfr wprost i wspak).WynikiNie zaobserwowano istotnych różnic pomiędzy analizowanymi grupami w zakresie FA. Grupa pacjentów z istotnie dłużej niż grupa kontrolna wykonywała testy TMT-A i TMT-B oraz uzyskała niższe wyniki w teście powtarzania cyfr. Krewni pacjentów uzyskali wyniki niższe w porównaniu z kontrolą w zakresie testu powtarzania cyfr oraz dłużej wykonywali test TMT-B. Nie obserwowano istotnych różnic pomiędzy badanymi grupami w zakresie liczby błędów przy wykonywaniu testów TMT-A i TMT-B.WnioskiWyniki przeprowadzonych przez nas badań neuropsychologicznych wskazują na obniżenie wyników w zakresie pojemności pamięci bezpośredniej, pamięci operacyjnej, plastyczności poznawczej oraz podzielności uwagi zarówno u pacjentów EOS jak i ich krewnych I stopnia w porównaniu z osobami zdrowymi. Stwierdzane deficyty neuropsychologiczne nie znalazły odzwierciedlenia w ocenie integralności istoty białej, mierzonej miarą FA.
Deforestation in the Amazon: What is illegal and what is not?
Authors: Hummel Antônio Carlos 
Published: December 2016

Abstract
Brazil has succeeded in reducing deforestation rates in the Amazon, but has not succeeded in explaining to the general public how much of this deforestation was illegal and how much was legally authorized. Transparency of deforestation data is limited, and pertinent legislation is little understood and poorly applied in practice. Lack of dissemination of information on authorized clearing of vegetation and lack of implementation of regulatory frameworks are contentious issues when defining strategies to reach zero deforestation in the Amazon region and for building policies related to climate change mitigation. The need to establish the new Forest Code provides an opportunity to establish goals and regulations for zero deforestation. This paper provides recommendations on how to communicate this information to the general public, how to make regulatory instruments effective and how to implement a zero deforestation agenda.
Care of the open wound in abdominal sepsis
Authors: Westrate J T.M. 
Published: December 2016

A recent development in the treatment of patients with intra-abdominal sepsis is to leave the abdomen open after the first laparotomy, thus presenting nurses with the problem of adequate wound care. Over the past 10 years, nurses in the surgical intensive care unit at University Hospital Rotterdam have developed an improved wound-dressing routine, consisting of the application of a large surgical film dressing over the entire abdominal wound. Two suction catheters are positioned under the film, and these are connected to a low-vacuum suction system (1-2kPa) to allow wound drainage. The effectiveness of this method was evaluated in 12 patients. The overall results showed that patients needed a change of dressing once every six days and the majority of problems related to the traditional method of wound care were overcome.
Entrepreneurial orientation in local authorities: A case study of the health care network in Lorraine
Authors: Nobile Didier , Husson Julien 
Published: December 2016

Abstract
This article examines the entrepreneurial dimension in local authorities. We use intervention research conducted at the Lorraine Regional Council in France (Conseil Régional de Lorraine), which decided to develop its health care and biotechnologies network, to show that the notion of entrepreneurial orientation is highly relevant in the local authority context. We also conclude that while this particular local authority demonstrates a tendency for innovativeness, proactiveness and risk-taking, the social dimension is a key feature of its entrepreneurial orientation, and consequently argue that particular attention be paid to this feature.
Prevalência de doenças ocupacionais em professores de uma instituição de ensino superior do Vale do Itajaí-SC
Authors: MORENO Leonel de Alencar , DIAS Maria Aparecida Florêncio , SARDÁ JUNIOR Jamir , DIAS Israel Domingos 
Published: December 2016

Há uma importante prevalência de doenças ocupacionais associadas às diversas atividades laborais. Docentes do ensino superior também são acometidos por doenças ocupacionais, todavia, há necessidade de mais pesquisas sobre o assunto. O presente trabalho investigou a prevalência de doenças ocupacionais em docentes de uma universidade localizada no Vale do Itajaí-SC, durante o período de 2013 a 2014, e os fatores associados a estas doenças, comparando-os com a literatura. Trata-se de uma pesquisa quantitativa, utilizando para a coleta de dados um questionário eletrônico, disponibilizado por meio de link on-line a todos participantes. Cinquenta e sete docentes responderam ao questionário. Os dados foram analisados através de análises de frequência e correlações. Os resultados indicam que os docentes têm uma jornada de trabalho de 44 horas em média, uma idade média de 42 anos, atuando aproximadamente há 17 anos na docência. A prevalência de hipertensão e cefaleia foi de 16% e de dorsalgia 49%. Os professores também apresentam com frequência sintomas de ansiedade, depressão, estresse e distúrbios do sono. A presença de doenças e sintomas psíquicos reportados pelos docentes confirmam as evidências descritas na literatura, ratificando que o exercício de determinadas atividades laborais pode ser um fator concausal na etiologia de doenças. Os resultados deste estudo podem fornecer subsídios para que as Instituições de Ensino Superior desenvolvam estratégias de promoção à saúde e métodos preventivos ou curativos das doenças ocupacionais.
Single-shot phase-measuring deflectometry for cornea measurement
Authors: Liang Hanning , Olesch Evelyn , Yang Zheng , Häusler Gerd 
Published: December 2016

Abstract
Phase-measuring deflectometry (PMD) has become a standard tool to measure the topography of specular surfaces. We implemented PMD for the measurement of the human cornea topography, exploiting an earlier idea of Lingelbach et al. Two problems occur: a large angular dynamical range and a single-shot measurement are required. We solve these problems by an optimized geometry with minimal occlusion and by single sideband demodulation with a pre-distorted fringe pattern with optimal fringe period. An in vivo measurement of an astigmatic cornea displays a deviation from the medical diagnosis of only 0.15 D, which is within the medical quantization step of 0.25 D.
Infrared deflectometry for the inspection of diffusely specular surfaces
Authors: Höfer Sebastian , Burke Jan , Heizmann Michael 
Published: December 2016

Abstract
Deflectometry is a full-field gradient technique that lends itself very well to testing specular surfaces. It uses the geometry of specular reflection to determine the gradient of the surface under inspection. In consequence, a necessary precondition to apply deflectometry is the presence of at least partially specular reflection. Surfaces with larger roughness have increasingly diffuse reflection characteristics, making them inaccessible to usual deflectometry. However, many industrially relevant surfaces exist that change their reflection characteristic during production and processing. An example is metal sheets that are used as car body parts. Whereas the molded but otherwise raw metal sheets show a mostly diffuse reflection without sufficient specular reflection, the final car body panels have a high specular reflectance due to the lacquering. In consequence, it would be advantageous to apply the same inspection approach both for the raw material and for the final product. To solve this challenge, specular reflection from rough surfaces can be achieved using light with a larger wavelength, as the specular reflectivity of a surface depends on the ratio of the surface roughness and the wavelength of the light applied. Wavelengths in the thermal infrared range create enough specular reflection to apply deflectometry on many visually rough metal surfaces. This contribution presents the principles of thermal deflectometry, its special challenges, and illustrates its use with examples from the inspection of industrially produced surfaces.
A Coplanar Waveguide Resonator Based In-Line Material Characterization Sensor for Bulk and Metallized Dielectrics
Authors: Talai Armin , Gold Gerald , Frank Martin , Mann Sebastian , Weigel Robert , Koelpin Alexander 
Published: December 2016

AbstractMicrowave Materials such as Rogers RO3003 are subject to process-related fluctuations in terms of the relative permittivity and dielectric loss. The behavior of high frequency circuits like patch-antenna arrays and their distribution networks is dependent on the effective wavelength. Therefore, fluctuations of the complex permittivity will influence the resonance frequency and beam direction of the antennas. This paper presents a grounded coplanar waveguide based sensor, which can measure the complex permittivity at 77 GHz, as well as at other resonance frequencies, by applying it on top of the manufactured depaneling. The relative permittivity of the material under test (MUT) is a function of the resonance frequency shift and the dielectric loss of the MUT can be determined by transmission amplitude variations at the resonances. In addition, the sensor is robust against floating ground metallizations on inner printed circuit board layers, which are typically distributed over the entire surface below antennas. Furthermore, the impact from conductor surface roughness on the measured permittivity values is determined using the Gradient Model.
The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease
Authors: Small Donna M. , Doherty Declan F. , Dougan Caoifa M. , Weldon Sinéad , Taggart Clifford C. 
Published: December 2016

Abstract
Members of the whey acidic protein (WAP) or WAP four-disulfide-core (WFDC) family of proteins are a relatively under-explored family of low molecular weight proteins. The two most prominent WFDC proteins, secretory leukocyte protease inhibitor (SLPI) and elafin (or the precursor, trappin-2), have been shown to possess multiple functions including anti-protease, anti-bacterial, anti-viral and anti-inflammatory properties. It is therefore of no surprise that both SLPI and elafin/trappin-2 have been developed as potential therapeutics. Given the abundance of SLPI and elafin/trappin-2 in the human lung, most work in the area of WFDC research has focused on the role of WFDC proteins in protecting the lung from proteolytic attack. In this review, we will outline the current evidence regarding the expanding role of WFDC protein function with a focus on WFDC activity in lung disease as well as emerging data regarding the function of some of the more recently described WFDC proteins.
Unbalanced bilingualism, diglossia and class division in postcolonial law
Authors: Powell Richard 
Published: December 2016

AbstractA number of postcolonial jurisdictions function bilingually as a result of policies to open up law to indigenous languages. Planned bilingualism is typical of Asian polities that inherited English-based common law, with Bangladesh, Hong Kong, India, Malaysia, Myanmar and Pakistan all use languages other than English in legal documents and courtroom proceedings. There are also bilingual practices in the hybrid law of Sri Lanka and the Philippines and the civil law of former Portuguese colonies such as Timor Leste and Macao. Bilingualisation typically begins with innovation in the legal lexicon and proceeds to the translation or bilingual drafting of legal texts in order to facilitate use of a second language in litigation and jurisprudence. It may be an interim process ushering in comprehensive vernacularisation, but more often it results in the long-term cohabitation of two or more languages within the legal domain. This study is interested in the implications of such cohabitation for legal practitioners. Focusing primarily on Malaysia while making comparisons with other Asian jurisdictions, it considers the largely political motivations behind language-in-law policies, reviews the process and reception of planning and explores how language choice in legal education may affect career paths. Despite the empowering agendas behind much of the language planning that has gone on, in most cases a balanced bilingual profession remains an elusive goal.
Role of distraction osteogenesis in craniomaxillofacial surgery
Authors: Ernst Nicole , Adolphs Nicolai 
Published: December 2016

Abstract
In the field of orthopedic surgery, distraction osteogenesis (DO) is well known for limb lengthening procedures or secondary corrective surgery in the fracture treatment of the extremities. The principle of gradual expansion of bone and surrounding soft tissues as originally described by G.A. Ilizarov is also applicable to the craniofacial skeleton when growth deficiency is present, and the patients affected by craniofacial or dentofacial anomalies may require distraction procedures. The surgical management is comparable. After osteotomy and the mounting of a specific craniomaxillofacial distraction device, active distraction is started after a latency phase of several days, with a distraction rate of up to 1 mm/day until the desired amount of distraction has been achieved. Subsequently, distractors are locked to provide appropriate stability within the distraction zone for callus mineralization during the consolidation phase of 3–6 months, which is followed by a further remodeling of the bony regenerate. After 14 years of clinical application, the role and significance of craniomaxillofacial DO are discussed after reviewing the files of all patients who were treated by craniomaxillofacial distraction procedures.
Preparation of TiO2/C Photocatalyst by Ethanol Modification of Hydrolysed Titania TiO(OH)2 in a Pressure Reactor
Authors: Janus Magdalena , Toyoda Masahiro , Inagaki Michio , Tryba Beata , Morawski Antoni W. 
Published: December 2016

AbstractA new way of preparation of TiO