bluuebunny/crossref_metadata_2025_split huggingface dataset:
Структура та поширеність поліорганної патології корів післяродового періоду
Authors: Zubkov O.O. , Skliarov P.M. 
Published: November 2017

Among the diseases of the postpartum period, the most common are ketosis, hypo-luteolysis, subinvolution of the uterus, hypocalcemia, delayed afterbirth and endometritis. These pathologies exert the greatest influence on the further course of lactation and may even call into question the further productive use of animals. To date, there is a lot of information about these diseases separately, and very few people pay attention to the combination of ketosis-endometritis, endometritis-hypoluteolysis and ketosis-endometritis-hypoluteolysis as a polyorganis pathology. In connection with the foregoing, the aim of the work was to determine the structure and prevalence of multi-organ pathology of postpartum cows in the conditions of a particular farm.The total number of 290 cows of the postpartum period was subject to research. Of these, obstetric pathologies were detected in 230 animals (79%), including ketosis of 23 head (8%), endometritis – 38 head (13%), hypoluteolysis – 35 head (12%) and concomitant diseases: ketosis endometritis – 55 head (19%), ketosis-hypoluteolysis – 29 heads (10%), endometritis-hypoluteolysis – 29 heads (10%) and ketosis-endometritis-hypoluteolysis – 20 heads (7%).Thus, only 21% of the total herd of cows were clinically healthy, 8% ‒ had ketosis, 12% had ‒ hypolyteolysis, and 13% had ‒ endometritis. Diagnosis for diorgan pathology of endometritis-hypoluteolysis and ketosis-hypoluteolysis was established in 10%, ketosis-endometritis in 19%. The multi-organ pathology of ketosis-endometritis-hypoluteolysis was recorded in 7% of animals.
Prevalence of bipolar disorder in a sample of older adults
Authors: Bisol Luísa Weber , Porciúncula Letícia Rodrigues , Mello Elisa Fasolin , Nogueira Eduardo Lopes , Gomes Irênio , Cataldo Neto Alfredo 
Published: November 2017

***Prevalence of bipolar disorder in a sample of older adults***AIMS: To estimate the prevalence of bipolar disorder in a sample of older adults and to examine associated socio-demographic and clinical factors.METHODS: Cross-sectional population-based study of individuals aged 60 years or older registered with the Family Health Strategy in Porto Alegre, Rio Grande do Sul, Brazil, selected randomly from 30 different basic health units. Participants were subjected to diagnostic assessment for bipolar disorder and suicide risk using the Mini International Neuropsychiatric Interview Plus 5.0.0. Categorical variables were described as absolute and relative frequencies. Quantitative variables were expressed as means and standard deviations. The Pearson chi-square or Fisher’s exact tests were used as appropriate to evaluate potential associations between the independent variables suicide attempt and risk of suicide. To control for possible confounders and assess variables independently associated with the outcome of interest, the strength association among different risk factors was assessed by means of prevalence ratios, which were estimated with a controlled Poisson model or multivariate Poisson regression. The significance level was set at 5% (p≤0.05).RESULTS: The sample comprised 550 older adults. The lifetime prevalence of bipolar disorder in the sample was 5.8% and the point prevalence was 1.5%. In those with bipolar disorder, 59.4% were type I and 40.6% type II. Significant associations were observed between bipolar disorder regardless of type and female gender (prevalence rate [PR] 2.42, 95% confidence interval [CI] 1.01-5.81), living with a partner (PR 2.52, 95%CI 1.21-5.24), history of suicide attempt (PR 3.16, 95%CI 1.53-6.25), and suicide risk (PR 2.98, 95%CI 1.47-6.06). When analyzed each type of bipolar disorder, statistically significant associations were found between age under 70 years and type I bipolar disorder; having companion and type II bipolar disorder; and risk of suicide was associated with both types of bipolar disorder.CONCLUSIONS: Regardless of the type of bipolar disorder, women and those living with a partner were more affected. History of suicide attempts and suicide risk were more frequent in elderly subjects with bipolar disorder than in those without the disorder.
Correlation of HDL cholesterol serum and Wagner’s severity level of diabetic foot ulcers
Authors: Kartono Tommy , Mallapasi Muhammad Nuralim , Mulawardi Mulawardi , Laidding Sachraswaty R. , Aminyoto Meiliati , Prihantono Prihantono 
Published: November 2017

Background: Diabetic foot ulcers are one of the leading causes of amputation in non-traumatic patients. This research aimed to investigate the correlation between the level of HDL cholesterol and the severity level of diabetic foot ulcer based on Wagner classification. The study conducted at Wahidin Sudirohusodo Hospital, Makassar, Indonesia.Methods: This is an observational study with the cross-sectional design. The data collected before and after the treatment. The change of the levels of HDL cholesterol and the severity level of the diabetic foot ulcer based on Wagner classification during the treatment were analyzed. Data analyzed using Spearman Correlation test, the paired t-test to assess the change in the levels of HDL cholesterol and the levels of severity of diabetic foot ulcer based on Wagner classification at the time admission and after the treatment. ANOVA test was used to observe the reduction significance of the severity of diabetic foot ulcer based on Wagner classification, and it was categorized as significant if p<0.05.Results: The results indicated that there is a correlation between the level of HDL cholesterol and the severity level of diabetic foot ulcer based on Wagner classification either at the early treatment with p-value = 0.003 (r = - 0.448) and the end of the treatment with p-value = 0.001(r = - 0.477). The lower of the level of cholesterol HDL, the higher was the severity level of the diabetic foot ulcer. Meanwhile, the correlation between the increase of the level of HDL cholesterol and the reduction of Wagner classification during the treatment was statistically insignificant with p-value = 0.100 (r = - 0.215).Conclusions: there was a correlation between elevated HDL cholesterol levels during treatment with Wagner classification decrease during treatment, the higher the HDL change, the higher the Wagner classification, but this was weak correlation and statistically insignificant.
Analysis of FNAC in diagnosis of lymphadenopathy-a retrospective study from a regional cancer centre, Cuttack, Odisha
Authors: Pathy Pramod Chandra , Hota Subhransu Kumar , Dash Sashibhusan , Samantaray Sagarika , Panda Sasmita , Rout Niranjan 
Published: November 2017

Background: Lymphadenopathy is one of the most common clinical presentations and major causes of morbidity. Thus, clinical recognition and urgent diagnosis is of paramount importance. So, we aimed to analysis the diagnostic role of fine needle aspiration cytology (FNAC) in superficial lymphadenopathy in a regional cancer centre, Odisha, India.Methods: A total 1129 cases were retrieved from the hospital record retrospectively from the patients who had presented with superficial lymphadenopathy from January 2015 to December 2015.Results: Out of 1129 lymphadenopathy cases, 671 (59.43%) were male and 458 (40.56%) were female with male to female ratio 1.46:1. The age of the patients ranged from 4 years to 83 years with mean age 48.57 years. The most common site was observed in cervical lymph node 493 (43.66%) followed by submandibuar lymph nodes 198 (17.53%) and supraclavicular lymph nodes 172 (15.23%). 584 (51.27%) were malignant and 545 (48.27%) were benign. Reactive hyperplasia was most common 318 (58.34%) among benign cases where as metastatic squamous cell carcinoma was the most common 261 (50.77%) among malignant lesions. By FNAC all benign lesions were correctly diagnosed, and primary sites of malignancy identified in 442 (85.59%) cases. Cyto-histo correlation was done in 399 cases. The overall diagnostic accuracy of FNAC was found to be 93.98%, sensitivity 93.88%, specificity 94.64%, positive predictive value 99.8% and negative predictive value 71.62%.Conclusions: FNAC is a highly sensitive and specific tool for early detecting primary malignancy and metastatic lesions. Many inflammatory lesions can be treated based on FNAC alone.
Haemolysis by urea: a simple method to improve quality of pre and post stained fine needle aspiration smears
Authors: Simon K. Ankita , Gadkari Rasika Uday , Dattar Sonali , Shrikhande Anuradha Vijay 
Published: November 2017

Background: Fine needle aspiration smears may contain large amount of blood which obscures cell morphology and cause inadequacy of smears in guided aspirates and highly vascular tumors. Resolving this problem can be done by urea. Red cell lysis by urea is a simple technique without affecting the diagnostic material of smears or losing them during the procedure. To evaluate utility of urea solution for red cell lysis for improving the adequacy of prestained and Poststained smears.Methods: For prestained and Poststained slides urea concentration, time of alcohol fixation and time in urea were standardized. Ethanol fixed smears are placed in coplin jars containing urea solution and then transferred back to ethanol fixative and stained routinely. Stained smears coverslip is removed then placed in urea solution which are later transferred back to ethanol fixative and stained routinely. Conventional and urea smears are compared using scoring system by Mair et al.Results: Urea treated smears had a cleaner background when compared with conventional smears with preservation of cell morphology in ethanol fixed smears. Stastical analysis showed significant improvement in adequacy of smears after urea treatment of smears.Conclusions: The technique is reliable and applicable method to improve the adequacy of cytology smears.
Metastatic germ cell tumor with complete response-7 years follow up
Authors: Jakovljevic Branislava Golub , Đokanović Dejan , Miličević Snježana , Škobić Anđa , Ćazić Dejan , Krivokuća Vladimir 
Published: November 2017

Cancer of the testis is a relatively uncommon disease, accounting for approximately 1-1.5% of all cancers in males. 5% of the malignant germ cell tumors are made of extragonadal origin. Germ cell tumors occur in men younger, usually between 20 and 35 years old. We report a case of a patient with metastatic extragonadal germ cell tumor with multiple sites of metastases, and very high initial values of tumor marker human chorionic gonadotrophin (HCG)- 1351308. At the time of diagnosis, the patient was in a very poor general condition. After the applied chemotherapy, there was a complete response and 7 years later the patient is without any symptoms of disease.
Head neck neuroblastoma in early childhood: a rare case report
Authors: Das Amit Kumar , Sengupta Prashant , Singh Richa , Kihemba Kas 
Published: November 2017

Neuroendocrine tumors (NETs) comprise a heterogeneous group of malignancies from cells derived from the neural crest with neuroendocrine differentiation. Neuroblastoma is an embryonal malignancy of the sympathetic nervous system arising from neuroblasts (pluripotent sympathetic cells). It can be sporadic or nonfamilial in origin. Despite the differences in the site of origin, nomenclature, biological behaviour, and functional status, NETs share certain immunohistochemical and ultrastructural features. NETs are relatively rare tumors with an annual incidence of 6 new cases per 100000 inhabitants. It is primarily a tumor of abdominal origin from where it metastasizes to lymph nodes, liver, orbital sites, and central nervous system. Head and neck NETs are uncommon. We report a rare case of neuroblastoma in a 3-year-old child presenting with an unusual large fungating mass in left parotid region.
Neurological outcome and postoperative stability after anterior cervical spine fixation by the use of cervical spine locking plate
Authors: Manzoor Ch Ali , Irshad Muhammad , Aamir Muhammad 
Published: November 2017

Background: The fractures of cervical spine are divided into upper cervical spine (C1-C2) and lower cervical spine (C3-C7) also called sub axial cervical spine. Sub axial cervical injuries are common, ranging in severity from minor ligamentous strain or spinous process fracture to complete fracture dislocation with bone and ligament disruption, resulting in severe spinal cord injury. The objective of this study was to determine the neurological outcome and postoperative stability after anterior cervical spine fixation by the use of cervical spine locking plate (CSLP) attached with cancellous screws.Methods: This descriptive study was carried out in the Department of Neurosurgery, Nishtar Hospital, Multan, Pakistan. One hundred and fifteen patients fulfilled the inclusion criteria were selected. Patient of either gender more than 15 years of age and less than 60 years of age having unstable lower cervical spine injuries from C-3 to C 7 on X-ray underwent anterior cervical fixation.Results: Age range from 15 to 60 years with mean 32.34±standard deviation (SD) =12.06. The mean Frankel grading of the patients was 3.26±standard deviation (SD) =1.33. There were 97 (84.3%) male patients and 18 (15.7%) female patients. The neurological outcome was good in 107(89.6%) patients and poor in 12 (10.4%). The postoperative stability was YES in 109 (94.8%) patients and NO in 06 (5.2%). In the mode of injury there were 65 (56.5%) patients having road traffic accident, 41 (35.7%) patients having fall from tree/roof/stairs, 6 (65.2%) patients having fall of brick on the patient, 1 (0.9%) patient having Buffalo hit/animal contact, 2 (1.7%) patient having contact of head at floor of swimming pool after jumped in.Conclusions: It is concluded from this study that good results were achieved with the use of the CSLP. The use of anterior approach in treatment of the injured lower spine is safe and effective.
Is it possible to alleviate thoracic surgery? chest tube removal before the extubation
Authors: Hazem Zribi , Ahmed Ben Ayed , Amina Abdelkbir , Sarra Maazaoui , Mahdi Abdennadher , Taher Mestiri , Adel Marghli 
Published: November 2017

Background: The ambulatory surgery (AS), is an operative management that does not require an overnight hospital stay. But, the application of AS still limited in the thoracic surgery due to the necessity of air leaking management. The aim of this study is to review our AS institutional experience by a chest drain removal before the extubation, in thoracic sympathectomy surgery.Methods: We have carried out a retrospective analysis of patients who underwent thoracic sympathectomy between November 2012 and July 2016 in the Thoracic Surgery Department of Abderrahmen MAMI University Hospital.Results: During the study period, 17 patients underwent thoracic bilateral sympathectomy. Twelve (12) females were operated versus 5 males. The mean age was 24.47 (range:17-33) years. There is no chest X-ray disorder detected during all frame times. No patient had developed a respiratory distress during the postoperative period. In addition to that, no postoperative morbidities had been detected during the follow up. All patients were satisfied about the procedure at the end of the follow up.Conclusions: The ambulatory thoracic surgery procedures can safely, and efficiency be applied if the patient is well selected. The progression on operative mini invasive techniques will increase the number of patients who can profit from an "alleviated thoracic surgery".
To compare the efficacy of topical negative pressure dressing with that of conventional moist wound dressings, in healing of wounds
Authors: Hebsur Narayanchandra I. , Pandey Kalyan , Puttannavar Girish 
Published: November 2017

Background: Wounds and their management are fundamental to the practice of surgery. In the past 15 years there have been significant advances in complex acute and chronic wound management. One of the most significant discoveries was the improvement in wounds with negative pressure–assisted wound closure. The aim and objective of the study was efficacy of topical negative pressure dressing with that of a control group using conventional moist wound dressings, in healing of wounds, were assessed with quality of wound healing.Methods: This prospective randomized controlled study 50 patients with acute and traumatic wounds, sub-acute wounds, chronic open wounds, of which 25 patients underwent topical negative pressure dressing. The remaining 25 patients underwent conventional moist wound dressings. The results were compared after second week. Wounds were assessed depending on wound size and percentage of reduction of wound size, wound bed score and increase in wound bed score, percentage of granulation tissue cover, graft take up as the percentage of ulcer surface area.Results: Our present study shows significant reduction in wound size, in the study group 19.52 cm2 as compare to control group, (6.64 cm2) found to be statistically significant (p <0.001). There is significant increase in wound bed score in the study group (mean difference was 9.60±2.16) where as in the control group there was not much increase in wound bed score (mean difference was 5.12±1.99) (p-valve 0.00001) which is statistically significant. The % of granulation tissue formation in the study group was 81.0±8.29 and in the control group was 53.60±19.23.Conclusions: Topical negative pressure dressing was better than conventional wound dressings in quality of wound healing.
A prospective clinico-pathological study of cervical lymphadenopathy
Authors: N. R. Narender , J. Yadagiri Rao 
Published: November 2017

Background: Lymphadenopathy refers to one or more lymph nodes that are abnormal in size, consistency or number. There are various causes for lymphadenopathy which range from benign conditions to malignant either primary or secondary from draining primary tumour. Lymphadenopathy can be localised to a single group or generalised.Methods: Prospective observational study was performed for the patients attending outpatient department of general surgery at Kamineni academy of medical sciences, LB nagar Hyderabad, Telangana with complaints of enlarged or swollen lymph nodes in the neck. This study included 46 cases. In cases where fine needle aspiration cytology was inconclusive and there was need for excision biopsy, only these cases were included in the study. After biopsy lymph node was sent for gross and microscopic examination for expert opinion from department of pathology.Results: The present study includes 46 patients in a period of two years from 01-8-2015 to 31-7-2017. Of these case tuberculosis lymphadenopathy (n=25,54.3%) was the most common aetiology followed by nonspecific chronic lymphadenopathy (n=16,34.7%) followed by some relatively rare cases and unusual presentation Schwannoma, pleomorphic adenoma, Kikuchi disease, non-Hodgkin’s lymphoma and secondaries from carcinoma tongue (n=1,2.1%).Conclusions: In the present prospective study tubercular lymphadenopathy was the most common cause for cervical lymphadenopathy followed by chronic nonspecific lymphadenopathy.
Evaluation of intestinal injuries from blunt abdominal trauma
Authors: U. D. Manoranjan , S. Nikhil , M. S. Chandrashekar 
Published: November 2017

Background: To Evaluate the cause, presentation, anatomical extent, diagnostic method, management and outcome of intestinal injuries from blunt abdominal injuries.Methods: The study included 40 patients who underwent laparotomy for intestinal injuries from blunt abdominal trauma over a period of 1 year. A retrospective study was conducted, and the patients were evaluated with respect to the cause, presentation, anatomical distribution, diagnostic methods, associated injuries, treatment and mortality.Results: 40 patients with 58 major injuries to the bowel and mesentery due to blunt abdominal trauma were reviewed. The male to female ratio was 9: 1 and the average age was 32.51 years. There were 38 injuries to the small intestine including 1 duodenal injury, 13 colonic injuries and 6 isolated injuries to the mesentery. Out of 29 patients with intestinal perforation, free peritoneal air was present on plain abdominal and chest radiography in 23 patients. The commonest injury was a perforation at the antimesenteric border of the small bowel. Treatment consisted of laparotomy followed by simple closure of the perforation, resection and anastomosis and repair followed by protective colostomy for colonic perforations. 3 (7.56%) deaths were recorded, while 6 (15%) patients developed major complications.Conclusions: Bowel and mesenteric injuries may be significant and require immediate surgery or may be nonsignificant and permit nonsurgical treatment. Although early recognition of intestinal injuries from blunt abdominal trauma is difficult only by clinical assessment, nevertheless important to establish the right diagnosis due to its high infective potential. Intestinal perforations are often found accompanying other severe intra-peritoneal injuries which probably, are the determining factors in morbidity and mortality hence the main emphasis lying on early detection of the injuries and reducing the time from admission to the surgery thus playing a role in the reduction of mortality and morbidity associated with intestinal injuries following blunt trauma abdomen.
Role of early debridement in non-healing ulcer
Authors: Tote Darshan , Jajoo Suhas , Tote Sachin 
Published: November 2017

Background: Non-healing wound is a commonly encountered entity with a broader effect on both the sufferer and the treating doctor. Time taken in healing these wound is directly related to financial loss as well as loss of working hours, thus ultimately increasing the financial burden. Chronic wound has devitalized tissue at the base which is barrier to cell migration and acts as supportive environment for bacterial growth. Considering the effect of devitalized tissue on wound healing there lies importance of debridement in wound management. Debridement is an effective technique to achieve desirable wound bed preparation by removing the dead and devitalized tissue. Hence a study was conducted at a rural hospital with main aim to assess role of surgical sharp debridement in non-healing wound in complete healing or preparing wound for further definitive treatment.Methods: The study was conducted at AVBRH Sawangi (Meghe), Wardha. Random 50 patients of non-healing ulcer were selected for the study. One group was of early debridement while other group of dressing with moist dressing only. Wound were assessed for healing, wound contraction, scar quality at regular intervals. They were assessed for duration of wound to heal completely/ get ready for further intervention like SSG/ Flaps, Cost of treatment and Time taken by the patient to return back to work.Results: 36% of patients in moist dressing group heal completely by 4 weeks while 56% of patients in debridement group heal completely by 4 weeks. Early recovery leads to early normalcy so less loss of wages and thus making the group cost effective.Conclusions: Early debridement was found to be an effective tool in wound healing in non-healing ulcers.