bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective marketing of high-rise luxury condominiums in a middle-income country like Sri Lanka
Authors: Anthonisz Stephan , Perry Chad 
Published: August 2016

Purpose
The purpose of this paper is to develop an effective process to market high-rise luxury condominiums in a middle-income country in Asia like Sri Lanka, based on empirical evidence.

Design/methodology/approach
The case research methodology used to address the four research issues used multiple sources of data. In stage 1, qualitative data were collected in interviews with managers and salespersons of six condominium developments that ranged from successful to failure. In stage 2, quantitative data were collected in a survey of the buyers of the six cases.

Findings
The authors contributions to knowledge include the first evidence-based findings about what influences the success and failure of high-rise luxury condominium developments in a country like Sri Lanka. In addition, a comprehensive marketing model of an effective marketing process is developed for forward-thinking professionals in the field to use to successfully market their luxury high-rise condominiums projects in the future.

Practical implications
Detailed steps for successful marketing are outlined, from the Board of Management down to salespersons.

Originality/value
This is the first academic research paper to examine the effective marketing of high-rise luxury condominiums in a middle-income country like Sri Lanka.
The impact of work-based research projects at postgraduate level
Authors: Costley Carol , Abukari Abdulai 
Published: August 2016

PurposeThe purpose of this paper is to examine the impact of work-based research projects at postgraduate level. The focus of this paper is to measure the impact of masters- and doctoral-level work-based projects which was the specific contribution of one group of researchers to the Nixonet al.’s (2008) study.Design/methodology/approachThis paper is based on data generated as part of a wider study that examines the impact of work-based learning projects across undergraduate through to doctoral level from the perspective of employers and from the employees perspective. The research study is based on a sample of alumni who had graduated from work-based masters and professional doctorate programmes and their corresponding employers in a UK higher education institution.FindingsAt masters and doctorate level the work-based project can often make an impact on the work context and also have a developmental effect on the employee who becomes a practitioner-researcher to undertake the project.Originality/valueThis paper finds that work-based projects are often an investment that companies make that have the propensity to yield tangible business success as well as providing an incentive for key staff to remain in the company and achieve university recognition.
Canadian think tanks and business research: an annotated Bibliography
Authors: Jones Rhiannon 
Published: August 2016

Purpose
The purpose of this annotated bibliography is to examine Canadian think tanks and their use for business research. This bibliography is aimed at business researchers, both academic and professional, entrepreneurs and librarians interested in exploring open access think tank publications.

Design/methodology/approach
The author chose prominent think tanks from across Canada in terms of relevance to business and economics. The organizations were selected based on open access options, ease of use, currency and geographical focus to optimize research areas.

Findings
Most of the organizations that were examined, emphasized current issues broadly applicable to Canadian business research. The think tanks differed in style and focus, yet all had appropriate applications for business research.

Originality/value
This annotated bibliography presents a unique Canadian perspective on business research by focusing on reputable open access resources.
Extreme climate events counteract the effects of climate and land‐use changes in Alpine tree lines
Authors: Barros Ceres , Guéguen Maya , Douzet Rolland , Carboni Marta , Boulangeat Isabelle , Zimmermann Niklaus E. , Münkemüller Tamara , Thuiller Wilfried 
Published: August 2016

Summary

Climate change and extreme events, such as drought, threaten ecosystems world‐wide and in particular mountain ecosystems, where species often live at their environmental tolerance limits. In the European Alps, plant communities are also influenced by land‐use abandonment leading to woody encroachment of subalpine and alpine grasslands.

In this study, we explored how the forest–grassland ecotone of Alpine tree lines will respond to gradual climate warming, drought events and land‐use change in terms of forest expansion rates, taxonomic diversity and functional composition. We used a previously validated dynamic vegetation model, FATE‐HD, parameterized for plant communities in the Ecrins National Park in the French Alps.

Our results showed that intense drought counteracted the forest expansion at higher elevations driven by land‐use abandonment and climate change, especially when combined with high drought frequency (occurring every 2 or less than 2 years).

Furthermore, intense and frequent drought accelerated the rates of taxonomic change and resulted in overall higher taxonomic spatial heterogeneity of the ecotone than would be expected under gradual climate and land‐use changes only.

Synthesis and applications. The results from our model show that intense and frequent drought counteracts forest expansion driven by climate and land‐use changes in the forest–grassland ecotone of Alpine tree lines. We argue that land‐use planning must consider the effects of extreme events, such as drought, as well as climate and land‐use changes, since extreme events might interfere with trends predicted under gradual climate warming and agricultural abandonment.
Utility of a brief index to measure diet quality of Australian preschoolers in the Feeding Healthy Food to Kids Randomised Controlled Trial
Authors: Duncanson Kerith , Lee Yu Qi , Burrows Tracy , Collins Clare 
Published: August 2016

AimThe aim was to evaluate the utility of a brief dietary intake assessment tool in measuring nutritional adequacy of preschoolers and differences in food and nutrient intake between quartiles stratified by overall diet quality.MethodsDietary intakes of preschoolers (n = 146) from the Feeding Healthy Food to Kids trial were reported by parents/caregivers using a 120‐item food frequency questionnaire (FFQ). Diet quality was assessed using the Australian Recommended Food Score for Preschoolers. Analyses were performed using Kruskal–Wallis one‐way analysis of variance, adjusted for Type 1 error. Participants were grouped into quartiles by total food score for comparison of subscale scores, food groups and nutrient intakes from the FFQ.ResultsParticipants who scored less than the median total food score of 36 were more likely to have suboptimal micronutrient intakes. Median fruit (9 vs 5, P < 0.0001) and vegetable (14 vs 7, P < 0.0001) subscale scores for preschoolers in the highest quartile were significantly higher than the lowest quartile, indicating much greater fruit and vegetable variety. Statistically significant differences in diet quality score by quartiles (P < 0.05) were found for total energy and percentage energy from core foods, protein, fibre and 11 micronutrients.ConclusionsThe Australian Recommended Food Score for Preschoolers is a practical brief diet quality assessment tool to measure food variety and nutritional adequacy in Australian preschoolers. Stratifying children by baseline diet quality in future nutrition interventions is recommended in order to identify those who are likely to benefit or require more targeted approaches to address specific nutritional needs in order to optimise food and nutrient intakes.
Hyperglycemia is associated with increased risk of patient delay in pulmonary tuberculosis in rural areas
Authors: Wang Qiuzhen , Ma Aiguo , Han Xiuxia , Zhao Shanliang , Cai Jing , Kok Frans J. , Schouten Evert G. 
Published: August 2016

背景第一次出现肺结核(PTB)症状与诊断之间的间隔时间过长可导致结核不断传播,并且也增加了在社区中传染的风险,除此之外还可以导致疾病加重,死亡率增高。2型糖尿病(T2DM)患者发生PTB的风险更高。然而,目前还尚未完全明确T2DM对PTB的诊断延误有何影响。这项研究在中国的一个农村地区调查了高血糖(糖尿病与糖尿病前期)以及其他因素对PTB患者诊断延误的影响。方法在当前这项基于社区的调查研究中,从2011年9月至2013年12月在县结核病诊所连续招募了新诊断的年龄 ≥ 16岁的PTB患者。所有的受试者都要测定空腹血糖,并且使用一份结构化的问卷调查表收集基本信息。结果在2280名患者中,605名(26.5%)有高血糖。患者寻求医疗保健的中位数(四分位范围)时间为44(59)天。1754名受试者推迟了寻求医疗保健的时间,并且在年龄 ≥ 30岁的受试者中,高血糖与患者延迟就诊机率增加之间具有独立的相关性(优势比为2.10;95%置信区间为1.49‐2.97)。其他与患者延迟就诊有关的因素包括咳嗽、盗汗以及缺乏对典型结核病症状的认识。发生咯血与患者延迟就诊呈负相关。结论在这个结核病高发的农村地区中,患者延误就诊似乎是一个严重的问题。高血糖与患者延误就诊机率增加之间具有独立的相关性,因此导致患者出现更严重的临床表现。
Effect of fixed‐dose combinations of ezetimibe plus rosuvastatin in patients with primary hypercholesterolemia: MRS‐ROZE (Multicenter Randomized Study of ROsuvastatin and eZEtimibe)
Authors: Kim Kyung‐Jin , Kim Sang‐Hyun , Yoon Young Won , Rha Seung‐Woon , Hong Soon‐Jun , Kwak Choong‐Hwan , Kim Weon , Nam Chang‐Wook , Rhee Moo‐Yong , Park Tae‐Ho , Hong Taek‐Jong , Park Sungha , Ahn Youngkeun , Lee Namho , Jeon Hui‐Kyung , Jeon Dong‐Woon , Han Kyoo‐Rok , Moon Keon‐Woong , Chae In‐Ho , Kim Hyo‐soo 
Published: August 2016

SummaryAimWe aimed to compare the effects of fixed‐dose combinations of ezetimibe plus rosuvastatin to rosuvastatin alone in patients with primary hypercholesterolemia, including a subgroup analysis of patients with diabetes mellitus (DM) or metabolic syndrome (MetS).MethodThis multicenter eight‐week randomized double‐blind phase III study evaluated the safety and efficacy of fixed‐dose combinations of ezetimibe 10 mg plus rosuvastatin, compared with rosuvastatin alone in patients with primary hypercholesterolemia. Four hundred and seven patients with primary hypercholesterolemia who required lipid‐lowering treatment according to the ATP III guideline were randomized to one of the following six treatments for 8 weeks: fixed‐dose combinations with ezetimibe 10 mg daily plus rosuvastatin (5, 10, or 20 mg daily) or rosuvastatin alone (5, 10, or 20 mg daily).ResultsFixed‐dose combination of ezetimibe plus rosuvastatin significantly reduced LDL cholesterol, total cholesterol, and triglyceride levels compared with rosuvastatin alone. Depending on the rosuvastatin dose, these fixed‐dose combinations of ezetimibe plus rosuvastatin provided LDL cholesterol, total cholesterol, and triglyceride reductions of 56%–63%, 37%–43%, and 19%–24%, respectively. Moreover, the effect of combination treatment on cholesterol levels was more pronounced in patients with DM or MetS than in non‐DM or non‐MetS patients, respectively, whereas the effect of rosuvastatin alone did not differ between DM vs non‐DM or MetS vs non‐MetS patients.ConclusionFixed‐dose combinations of ezetimibe and rosuvastatin provided significantly superior efficacy to rosuvastatin alone in lowering LDL cholesterol, total cholesterol, and triglyceride levels. Moreover, the reduction rate was greater in patients with DM or MetS.
Re‐evaluation of progenitor thresholds and expectations for haematopoietic recovery based on an analysis of 810 autologous transplants: Implications for quality assurance
Authors: Watts Michael J. , Ings Stuart J. , Balsa Carmen , Antonio Andrew , Hack Simon , Linch David C. 
Published: August 2016

Haematological engraftment was assessed in 804 autologous transplants. Neutrophil recovery occurred in over 99% within 14 d but platelet recovery was delayed beyond this time in 14·8%. Time to recovery was dependent on the progenitor cell dose infused. The minimum CD34+ cell threshold adopted in this study (2 × 106/kg) was safe although recovery was faster with a dose >5 × 106/kg. CD34+ cell doses of between 1 and 2 × 106/kg were also acceptable if either the granulocyte‐macrophage colony‐forming cell dose exceeded 2 × 105/kg or this dose was due to splitting a higher yield harvest. Prompt neutrophil recovery affords important quality assurance for laboratory processing.
Nurturing the virtuous circle: Looked After Children's participation in reviews, a cyclical and relational process
Authors: Roesch‐Marsh Autumn , Gillies Andrew , Green Dominique 
Published: August 2016

AbstractChildren's participation in decision making of all kinds is of increasing interest across the world as more and more countries seek to comply with Article 12 of the United Nations Convention on the Rights of the Child. The participation rights of children who are in the care of the state are of particular concern. Recent research in England suggests that Independent Reviewing Officers (IROs) can play a crucial role in ensuring that looked after and accommodated children are able to participate in care planning and review processes. This paper outlines the findings of the first Scottish study to investigate the role of Reviewing Officers in encouraging children's participation in reviews. Surveys were collected from social workers, Reviewing Officers and young people after 69 review meetings as part of an action research study. Follow‐up qualitative interviews were then completed with 10 young people and a focus group held with the five participating Reviewing Officers. The findings suggest that participation in looked after reviews can best be understood as a cyclical and relational process and that taking part in action research may enhance participation practices. While the role of the Reviewing Officer was found to be important, the findings suggest that everyone involved in the care and support of the young person needs to encourage participation processes that are individualized.
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta‐analysis
Authors: Gorman D. , Ogston S. , Hussain S.S.M. 
Published: August 2016

BackgroundTonsillotomy (or intracapsular tonsillectomy) is a modern technique which is seen by some as potentially superior to traditional (extracapsular) tonsillectomy for the removal of tonsillar tissue to treat obstructive sleep apnoea in children. It has been suggested that peri‐operative pain and haemorrhage and postoperative haemorrhage are reduced with the tonsillotomy technique. However, no systematic reviews have been carried out to assess its efficacy in treating obstructive sleep apnoea compared to tonsillectomy.Objective of reviewTo assess whether subjective improvement in symptoms of obstructive sleep apnoea following tonsillotomy is comparable to that following tonsillectomy, measured using a standardised questionnaire, the Obstructive sleep apnoea‐18 (OSA‐18) tool.Type of reviewSystematic review of the literature and meta‐analysis.Search strategyPubMed (MEDLINE), followed by Ovid (MEDLINE), Cochrane Database of Systematic Reviews, American College of Physicians Journal Club, and the British Medical Journal were searched for articles published in English between 1995 and 2015 inclusive.Evaluation methodLiterature search, systematic review and meta‐analysis. Studies examining improvement in mean OSA‐18 score following tonsillotomy, improvement in mean OSA‐18 score following tonsillectomy, and examining both were selected, examined and used for meta‐analysis. Studies with and without concurrent adenoidectomy were included.ResultsFour studies examining tonsillotomy and 16 studies examining tonsillectomy were included in the analysis. Using a random effects model, the pooled improvement in OSA‐18 score for tonsillotomy was 2.46 (95% CI 1.92–2.99), and for tonsillectomy, it was 2.10 (95% CI 1.91–2.30). There was no significant difference between the methods.ConclusionThat there is no significant difference in subjective outcome between tonsillotomy and tonsillectomy may support wider use of tonsillotomy over tonsillectomy for the treatment of obstructive sleep apnoea in children.
Expression of embryonic stem cell markers in pyogenic granuloma
Authors: Blackwell Max G. , Itinteang Tinte , Chibnall Alice M. , Davis Paul F. , Tan Swee T. 
Published: August 2016

BackgroundRecent description of hemangioblastic blood islands within pyogenic granuloma (PG) has led us to investigate the expression of embryonic stem cell (ESC) markers in this tumor.MethodsIn this study we examined the expression of ESC markers, OCT4, SOX2, STAT3 and NANOG in PG samples from 11 patients, by immunohistochemical (IHC) staining, NanoString analysis and in situ hybridization (ISH).ResultsIHC staining demonstrated the expression of pSTAT3, OCT4, SOX2 and NANOG by the endothelium of the microvessels in PG whilst pSTAT3, SOX2 and NANOG were also expressed by cells in the interstitium, outside of the microvessels. NanoString and ISH analysis showed mRNA expression for STAT3, OCT4 and NANOG in PG.ConclusionsThe expression of the ESC markers, OCT4, SOX2, pSTAT3 and NANOG, suggests the endothelium of PG displays a primitive phenotype. Cells in the interstitium expressing pSTAT3, SOX2 and NANOG may represent a more downstream derivative of the primitive endothelium, or a separate population. The primitive nature of the endothelium and cells in the interstitium reveals novel insights into the biology of PG. To the best of our knowledge, this is the first demonstration of the expression of ESC markers in PG, implying the presence of a hematopoietic stem cell population.
Sebaceous mantleoma (mantle adenoma): reappraisal of the myth of the problematic benign neoplasm with sebaceous mantle differentiation
Authors: Goto Keisuke , Misago Noriyuki , Sumiya Noriyoshi , Ishikawa Yukio 
Published: August 2016

AbstractFew cases of a true benign neoplasm with sebaceous mantle differentiation have been reported, and little is known about this tumor. Herein, we present a rare case of the neoplasm called sebaceous mantleoma, along with a comparison of the histology and immunoprofile with those of normal sebaceous mantles. A pedunculated polyp occurred on the scalp of a 51‐year‐old woman. Histopathologically, the tumor showed lobulated epithelial‐mesenchymal units that were separated from the normal dermis by clefts. The lesion was composed of cords and columns of basaloid cells containing a few mature sebocytes, with a focal connection to infundibulocystic structures as well as dense fibrotic or fibromyxoid stroma. Immunohistochemically, androgen receptor, estrogen receptor, and CD117 were partially positive for the tumor, and CD8 (C8/144B) and epithelial membrane antigen were focally positive. Additionally, cytokeratin 20‐positive Merkel cells were individually admixed in the tumor nests as well as in normal sebaceous mantles. This case report reveals the characteristic histology and immunoprofile of this problematic benign neoplasm and helps to understand this entity.
Retrospektive Analyse von Zufallsbefunden, die bei Patienten mit kutanem malignen Malignom durch 18F‐Fluordeoxyglucose‐PET/CT erhoben wurden
Authors: Conrad Franziska , Winkens Thomas , Kaatz Martin , Goetze Steven , Freesmeyer Martin 
Published: August 2016

ZusammenfassungHintergrund und ZieleBei der 18F‐Fluordeoxyglucose‐Positronenemissionstomographie/Computertomographie (FDG‐PET/CT) ergeben sich häufig Zufallsbefunde. In der vorliegenden Studie konzentrierten wir uns auf mittels FDG‐PET/CT erhaltene Zufallsbefunde bei Patienten mit kutanem Melanom und überprüften deren Relevanz hinsichtlich weiterer diagnostischer Maßnahmen und Interventionen.Patienten und MethodenDie Krankenakten von 181 konsekutiven Melanom‐Patienten wurden retrospektiv ausgewertet, um das Management von Zufallsbefunden zu dokumentieren. Der Schwerpunkt lag dabei auf den histologischen Befunden.ErgebnisseBei 33 von 181 (18 %) Patienten lagen 39 relevante Zufallsbefunde vor, und zwar im Kolorektalbereich (n = 15 Patienten), in der Schilddrüse (n = 8), der Prostata (n = 2), dem Bewegungsapparat (n = 2), in Lymphknoten (n = 2), der Parotis (n = 1), den Mandeln (n = 1), den Nieren (n = 1) und der Gallenblase (n = 1). Bei 25 Patienten schlossen sich weitere diagnostische Verfahren an, wobei in 21 Fällen ein klinisches Korrelat nachgewiesen wurde. Bei 16 von 21 Patienten ergab sich eine Neoplasie, darunter fünf maligne Läsionen (vier Kolonkarzinome und ein Prostatakarzinom). Die Malignome wurden frühzeitig diagnostiziert und in der Mehrzahl der Fälle erfolgreich entfernt.SchlussfolgerungenDer Einsatz der FDG‐PET/CT als Routine‐Diagnostik wird in den Leitlinien empfohlen und ist indiziert bei malignem Melanom ab Stadium IIC. In dieser Studie wurden auf effektive Weise ansonsten nicht erkannte Krebserkrankungen, insbesondere Kolonkarzinome, detektiert. In den meisten Fällen war eine frühe Intervention möglich. Zufallsbefunde durch FDG‐PET/CT sollten, unter Berücksichtigung des Zustands und der Wünsche des Patienten, mit den geeigneten diagnostischen Maßnahmen abgeklärt werden.
Zum Stellenwert der Unterdruck‐Instillationstherapie in der Dermatologie
Authors: Müller Cornelia Sigrid Lissi , Burgard Barbara , Zimmerman Monika , Vogt Thomas , Pföhler Claudia 
Published: August 2016

ZusammenfassungDie Methoden zur Behandlung akuter und chronischer Wunden unterliegen einer steten Weiterentwicklung, Reevaluierung und Anwendung innovativer Therapieformen. Die Vakuumtherapie zur Wundbehandlung gehört zu den etablierten Behandlungsmodalitäten. Ein innovatives Verfahren kombiniert die Vakuumtherapie mit der automatisierten, kontrollierten Zufuhr und Drainage wirkstoffhaltiger Lösungen zur topischen Wundbehandlung im Wundbett und auch wirkstofffrei durch Instillation physiologischer Kochsalzlösung (Unterdruck‐Instillationstherapie). Hierdurch können die Effekte der konventionellen Vakuumtherapie mit denen der lokalen Antisepsis kombiniert werden. Hierdurch kommt es zu einer Reduktion der Wundfläche, einer Induktion von Granulationsgewebe sowie einer Reduktion der Keimbesiedelung der Wunden. Bisher publizierte Studien konzentrieren sich auf die Anwendung dieses Therapieverfahrens zur Behandlung orthopädisch‐chirurgischer Krankheiten. Die Datenlage bezüglich der Vakuum‐Instillationstherapie in der Dermatochirurgie beschränkt sich derzeit auf Fallberichte und Einzelfallerfahrungen. Randomisierte, prospektive Studien zum Vergleich der Vakuum‐Instillationstherapie zur Behandlung dermatologischer Krankheitsbilder existieren bislang nicht. Ziele des vorliegenden Artikels sind die Vorstellung der Vakuumtherapie mit Instillation einschließlich ihres Wirkprinzips, deren mögliche Komplikationen, die Diskussion erdenklicher Kontraindikationen sowie eine Übersicht über die aktuell verfügbare Datenlage. Zusammenfassend scheint sich die Evidenz zu verdichten, dass mittels Unterdruck‐Instillationstherapie sowohl einfache als auch komplizierte Wunden effizient behandelt werden können, was sich in einer deutlichen Beschleunigung der Wundgranulation mit konsekutiv früher möglichem Defektverschluss äußert.