bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective analysis of prescriptions in the management of lepra reactions: Results of a single center study from tertiary hospital in Maharashtra
Authors: Kulkarni Madhuri , Patil Anant , Aathawale Siddharth 
Published: May 2017

Objective: To examine pattern of lepra reaction andmedicines used in the treatment of lepra reactions in a tertiary hospital. Material methods: In this retrospective study, prescriptions of patients treated for the lepra reactions were reviewed to find out prevalence of type 1 and type 2 reactions and medicines used in the treatment of lepra reactions. Results:A total of66 patients (male 59.1%; female 40.9%) with mean age of 36.6 (+13.1) years were included in the study. Multibacillary leprosy was present in 93.7% patients. A total of 39 (60%) patients had type 2 reaction whereas 26 (40%) had type 1 reaction. Mean number of medicines per patients was 7.5. Prednisolone was used in 62 (93.9%) patients with mean duration of 33.32 (+33.2) days whereas chloroquine was used in 52 (78.8%) patients for 36.6 (+27.9) days. Thalidomide was used in 25 (37.9%) patients. Analgesic and anti-inflammatory and anti-acidity drugs were used in 63 (95.4%) patients each whereas paracetamol was given to 41 (62.1%) patients. Antihistamine, antimicrobial agent and vitamins were given to 27 (40.9%), 27 (40.9%) and 35 (53.0%) patients respectively. Conclusion:Lepra 2 reaction is more common than lepra 1 reaction. Prednisolone and chloroquine are the two most commonly used medicines in the treatment of lepra reaction. Similarly, thalidomide, older drug has emerged as common treatment for lepra reaction.
POTENTIAL BENEFIT OF CURCUMIN ADJUVANT THERAPY TO THE STANDARD H. PYLORI ERADICATION THERAPY IN PATIENTS WITH PEPTIC ULCER DISEASE
Authors: Abdulridha Manal Khalid 
Published: May 2017

Objective: This study was designed to explore the benefit of curcumin as adjuvant therapy to the standard H pylori eradication triple therapy in both duodenal and gastric ulcers patients. Methods: The present study enrolled 40 patients newly diagnosed endoscopically with peptic ulcer disease to be allocated into group1 treated with standard H. pylori eradication triple therapy, and group2 patients treated with curcumin (500mg) capsules three times daily for 14 day as adjuvant to standard triple therapy. Stool antigen test, immunoglobulin M serology test, tumor necrosis factor-alpha (TNF-α), interleukin 1 beta (IL1β), and total antioxidant capacity (T-AOC) are measured at the baseline and after 6 weeks of treatment.Results: The result showed that the use of curcumin as adjuvant therapy produced highly significant improvement in healing efficacy which was significantly distinguished in duodenal ulcer patients compared to gastric ulcer groups 2 patients (p <0.05), along with highly significant reduction in pro inflammatory IL1β level in group 2 patients(p<0.01). After 6 weeks of treatment there was highly significant elevation in level of TNF- α in groups 1 (p value <0.01), though, group 2 patients presented with non significant elevation in TNF-α level. Moreover, the total antioxidant capacity was improved with curcumin adjuvant therapy, though non- significant, compared to group 1patients who showed reduction in total antioxidant capacity.Conclusion: This study revealed that addition of curcumin as adjuvant therapy produced improvement in ulcer healing efficacy, and controlled the inflammatory and oxidative stress process induced by H pylori infection.Keywords: Peptic ulcer disease, Curcumin, H. pylori infection, inflammation and oxidation markers.
GC-MS ANALYSIS AND IN VITRO ANTIOXIDANT ACTIVITIES OF RUTA GRAVEOLENS L. FROM WESTERN GHATS REGION –SOUTH INDIA
Authors: Kathirvel Poonkodi , Poonkodi Kathirvel , Gomathi Kalimuthu , Akila Murugan 
Published: May 2017

Aims:The present study examines the chemical composition of essential oil of Ruta graveleons and antioxidant activity of petroleum ether and methanol extracts of dry leaves of R. graveleons which belongs to Rutaceae family found in many parts of the India. There are few reports are available for its essential oil in India.Materials and methods:The fresh leaves were hydrodistilled by Clevenger type apparatus, the obtained essential oil was analyzed using GC-MS. The petroleum ether and methanol extracts were tested for antioxidant activity by DPPH˙ and ABTS methods.Results:The GC-MS results showed that 2-nonanol (34.25), 2-nonanone (32.15) and nonyl ester (15.43) are the major components and some of the other minor compounds are 2-dodecanone (2.77), tri decanone (2.54) and tumeronol (2.16). The preliminary phytochemical investigation of petroleum ether and methanol extracts showed the presence of carbohydrates, phenolic compounds, flavonoids, furano coumarins, fatty acids and alkaloids. So an attempt was made to find the possible sources for future novel antioxidants in food and pharmaceutical formulations.Conclusions: GC-MS studies indicated that 2-nonanone (32.15) and nonyl ester (15.43) are the major components. The methanol extract showed highest IC50 values for DPPH (19.50±1.25 μg/ml) and ABTS (48.32±0.9 μg/ml) and petroleum ether extract showed moderate activity, both results are comparable with standard employed for each method.Keywords: Ruta graveolens, Rutaceae, Gas chromatography-mass spectrometry, Essential oil, antioxidant, 2,2-diphenyl-1-picrylhydrazyl, 2,2’-azinobis( 3-ethylbenzothiazoline-6-sulphonic acid).
ASSOCIATION BETWEEN RHEUMATOID ARTHRITIS AND HEALTH-RELATED QUALITY OF LIFE IN KOREAN WOMEN AGED 50 YEARS AND OVER
Authors: Park Hyejin 
Published: May 2017

Objective: The purpose of this study is to evaluate the association between rheumatoid arthritis (RA) and health-related quality of life (HRQoL) in Korean women.Methods: Participants (n=2068) aged 50 years or older were selected from Korea National Health and Nutrition Examination Survey (KNHANES) 2005-2008. Sociodemographic characteristics, medical history of RA, and EuroQol-5 dimension were obtained from the KNHANES dataset.Results: The results revealed that demographic variables, including age, education level, income, exercise, smoking, and alcohol drinking, were important factors associated with HRQoL. In this study, RA was an important factor affecting HRQoL in Korean women. The adjusted odds ratio for HRQoL in participants with RA was 2.15 (95% confidence interval [CI]: 1.46-3.18, p=0.001) in mobility, 2.30 (95% CI: 1.60-3.32, p<0.001) in usual activities, and 3.41 (95% CI: 2.20-5.28, p<0.001) in pain/discomfort.Conclusion: These findings suggest that there is a strong associationbetween RA and HRQoL and preventing and controlling RA may significantly improve the quality of life for elderly Korean women. Keywords: Demographic factor, EuroQol-5 dimension, Health-related quality of life, Rheumatoid arthritis.
La criminalidad como tema historiográfico: Chile en el siglo XIX
Authors: Estay-Sepúlveda Juan Guillermo , Monteverde-Sánchez Alessandro 
Published: May 2017

La problemática de la criminología ha sido indagada por diversos historiadores a través del tiempo. Sin embargo, se ha encontrado con la carencia de falta de respuestas la cual ha sido suplida por estudios generales de acontecimientos y aproximaciones temáticas. Lo que se presenta es una tratativa de llenar un vacío con trabajos de significación, que al analizarlos cubren esta falencia en parte, y ayudan a entender el trabajo individual de varios investigadores, quienes han sistematizado una problemática. Se trata de una problemática recurrente y discursiva en la actualidad, la cual periódicamente se cubre de nuevas y valiosas interpretaciones. Al analizar las obras de los historiadores que han ingresado a la temática de la criminalidad y la criminología, queremos ser un aporte sustancial para desvelar nuevas interpretaciones y crear nuevo conocimiento.
La teoría del conocimiento de Berkeley: empirismo y colonialidad
Authors: Hernández-Castro Gustavo 
Published: May 2017

Se establece la relación existente entre la teoría del conocimiento de George Berkeley y su concordancia con la enunciación cognitiva construida en Europa para la instauración de un humanismo global. El empirismo de Berkeley, ha sido un puente sólido, para justificar la posibilidad de un conocimiento que, desde el sustento filosófico-teológico, desvincula al sujeto de la ontología y con ello, elimina la subjetividad de todo cuerpo y espacio geográfico. Con esto crea universalismos abstractos y justificados desde la política, la religión, el derecho, la economía, entre otras. Berkeley al establecer que percibir es lo mismo que existir, elimina la posibilidad de que el sujeto puede tener conciencia de sí y para sí y con esto, transformar su realidad.
Evaluación del efecto biocontrolador de Bacillus spp., frente a Fusarium spp., bajo condiciones de invernadero en Rosmarinus officinalis L
Authors: Bautista Diana , Corrales Ramírez MSC Lucía Constanza , Cuervo Andrade PhD Jairo Leonardo , González Lady , Guevara Marcela , Sánchez Leal MSC Ligia Consuelo 
Published: May 2017

El romero es una de las plantas aromáticas más importantes dentro del mercado de exportación colombiano. El cultivo de esta planta se ve afectado por marchitez vascular producida por Fusarium spp. El objetivo principal de este trabajo fue establecer en el romero el efecto biocontrolador de Bacillus spp., frente a Fusarium spp., bajo condiciones de invernadero. Para ello se seleccionaron Bacillus liqueniformis (B1), Bacillus subtilis (B2), Bacillus megaterium (B14), Bacillus brevis (E2), aislados de rizósfera de plantas aromáticas, a los cuales se les realizaron pruebas de viabilidad, identificación enzimática manual y automatizada, y pruebas de antagonismo in vitro en medio PDA frente a Fusarium acuminatum aislado de las plantas de romero, comprobando la patogenicidad del hongo por postulados de Koch.El ensayo se realizó con 30 plántulas de romero, un control negativo y uno positivo, bioensayos con sólo Bacillus spp., y tratamientos con Bacillus spp., más el patógeno. Para evaluar la severidad del patógeno y el comportamiento de las bacterias cada ensayo se realizó por triplicado y bajo condiciones de invernadero. En las pruebas de antagonismo in vitro B1 y B2 presentaron entre el 70–100% de inhibición del micelio y B14 y E2 entre el 40–69%. Los Bacillus spp., disminuyeron la severidad de la marchitez vascular en todos los ensayos; por la producción de sustancias antifúngicas facilitaron el aumento del peso seco de las hojas de las plantas al permitir la obtención de nutrientes y B14 aumentó la longitud de la raíz y el tallo. Se precisa secuenciar el aislamiento de Fusarium, para confirmar la especie.
Las bibliotecas públicas híbridas en el contexto brasileño
Authors: Da Silva Rafaela Carolina , Caldas Rosângela Formentini 
Published: May 2017

Las transformaciones sociales derivadas del uso de las Tecnologías de la Información y las Comunicaciones en los ambientes institucionales, en los cuales existe una actuación del profesional de la información, reflejan las diferentes perspectivas evidenciadas de las comunidades con las que trabajan. Se debe tener en cuenta que en el escenario brasileño existen pocos estudios acerca de las bibliotecas híbridas, lo que refleja la práctica de lo cotidiano en estas instituciones; si estas prácticas fuesen una constante se podrían constar beneficios ideales para las bibliotecas públicas. El objetivo de esta investigación es realizar una comparación de las actuaciones de las bibliotecas híbridas existentes en el contexto brasileño y, de ese modo, destacar la diferencia de grupos culturales híbridos en las localidades brasileñas. Se utilizó el método de estudio de casos múltiples en las bibliotecas: BSP/São Paulo, BNB/Brasilia y BHEGS/Bahía. Las bibliotecas públicas híbridas brasileñas tienen un elevado potencial para articular propuestas defendiendo nuevas posturas y concepciones de diseminación de información. Por tanto, las estrategias de desarrollo de comunidades que desean adoptar el modelo híbrido para sus bibliotecas deben orientarse hacia el acceso a la información, por medio de políticas públicas, tecnologías y estructuras organizacionales como aporte para la ciudadanía de los individuos que interactúan socialmente en sus localidades.
RUANG JELAJAH HOABINHIAN DI PULAU SUMATRA
Authors: Wiradnyana Ketut 
Published: May 2017

Thir article intends to interpret the Hoabinh Culture Dispersal from the Hoabinh culture presence on the western part of Sumatra island, with different activities period. It can be achieved by recognizing archaeological material and carbon analysis results, and is part to surveys dan excavation results. The results is Hoabinh occupation range at coastal and highlands. Carbon analysis explains that, Hoabinh migrationfrom the coast to the higlands. Menginterpretasikan alur sebaran atas keberadaan situs budaya Hoabinh di Pulau Sumatra bagian utara,dengan berbagai perbedaan masa aktivitasnya, merupakan tujuan dari uraian artikel ini. Hal tersebut dapat dicapai dengan mengenali sisa tinggalan arkeologisnya dan juga hasil analisa karbon yang merupakan bagian dari hasil kegiatan survei dan ekskavasi. Adapun hasilnya menyangkut ruang jelajah pendukung budaya Hoabinh di pesisir dan dataran tinggi. Dari data analisa karbon diketahui bahwa sebaran pendukung budaya Hoabinh itu berlangsung dari pesisir Pulau Sumatra ke wilayah dataran tinggi.
PRODUKSI DAN DISTRIBUSI GERABAH DI SITUS GUNUNG WINGKO: KAJIAN ARKEOLOGI EKONOMI
Authors: Alifah Alifah 
Published: May 2017

Mount Wingko site is one of the sites which is rich in artifacts and ecofacts findings. This research aims to understand how production and distribution activities occur in the community at Gunung Wingko site. This research applied economic archaeology approach with tray pottery artifacts as primary data supported by other findings. Based on the analysis, it is found that there are two activities at Mount Wingko site that is salt production and cattle raising. Formerly, distribution activity was done by exchange, then it was developed into trading. Situs Gunung Wingko merupakan salah satu situs yang kaya akan temuan artefak dan ekofak. Penelitian ini bertujuan untuk memahami bagaimana kegiatan produksi dan distribusi yang terjadi pada masyarakat di situs Gunug Wingko. Pendekatan yang digunakan adalah arkeologi ekonomi dengan data utama yang dipakai dalah artefak gerabah tampah dan didukung oleh temuan lain. Berdasarkan analisis yang dilakukan diketahui bahwa, di situs Gunung Wingko terdapat dua aktivitas produksi yaitu pembuatan garam dan pemeliharaan binatang. Aktivitas distribusi pada awalnya dilakukan secara pertukaran, kemudian berkembang menjadi perdagangan.
SITUS-SITUS ARKEOLOGI SEBAGAI MOTIVASI PENARIK (PULL FACTORS) WISATAWAN LANJUT USIA (SILVER TOURISM) BERKUNJUNG KE PROVINSI BALI
Authors: Astiti Ni Komang Ayu 
Published: May 2017

The potential and readiness of archaeological sites as good tourist destination from attraction, accessibility, amenity and community acceptability become important as one of the elderly tourists motivation to visit Bali. This research aims to explore the strategy management of archaeological sites as comfortable and secure cultural tourism attraction by conserving so that it becomes the pull factor of elderly tourist visit. The research was conducted by survey method and using combined analytical technique of quantitative and qualitative. From the data analysis, it is known that elderly tourists in Bali gives a positive value on diversity of cultural tourism attractions with activity visiting archaeological sites (17.89 %), visiting museum (9.47 %), religious or spiritual activity (18.95 %), enjoying Balinese people tradition (27.37 %), and attending cultural events of Bali (24.21 %). Management through zoning system formulation is quietly efective. Besides accessibility, Various facilities can be provided at the development zone which can motivate elderly tourists to visit. Today, the management of archaeological site in Bali has not given much attention to the facilities of elderly tourists and people with disabilities. Potensi dan kesiapan situs-situs arkeologi sebagai destinasi wisata baik dari atraksi, aksesbilitas, amenitas dan penerimaan masyarakat menjadi penting sebagai salah satu motivasi wisatawan lanjut usia untuk berkunjung. Tujuan penelitian ini adalah untuk mencari strategi pengelolaan situs-situs arkeologi sebagai atraksi wisata budaya yang nyaman dan aman dengan menjaga pelestarian sehingga menjadi motivasi penarik (pull factor) wisatawan lanjut usia berkunjung ke Bali. Penelitian dilakukan dengan metode survei dan menggunakan teknik analisis gabungan antara kuantitatif dan kualitatif. Dari analisis data diketahui bahwa wisatawan lanjut usia di Bali memberikan nilai positif pada keragaman atraksi wisata budaya dengan aktivitas berkunjung ke situs-situs arkeologi (17,89 %), ke museum (9,47 %), aktivitas religi/spritual (18,95 %), tradisi masyarakat Bali (27,37 %), dan event-event budaya Bali ( 24,21%). Pengelolaan dengan melakukan penataan sistem zoning sangat efektif, pada zona pengembangan dapat disediakan berbagai fasilitas yang dapat menjadi motivasi wisatawan lanjut usia berkunjung selain aksesbilitas. Pengelolaan situs-situs arkeologi di Bali saat ini belum banyak memberikan fasilitas khusus untuk kebutuhan wisatawan lanjut usia dan penyandang disabilitas.
MAKAM KUNO SUTAN NASINOK HARAHAP, POLA PENGUBURAN ETNIS BATAK ANGKOLA-MANDAILING DI PADANG LAWAS UTARA
Authors: Nasoichah Churmatin 
Published: May 2017

The purpose of this paper is to understand of the Ancient Tomb Complex of Sutan Nasinok Harahap and its relation to the tombs of ancient Batak in the territory of North Padang Lawas. In writing this paper uses inductive deductive reasoning which moved from the main data in the form of the Ancient Tomb of Sutan Nasinok Harahap associated pattern that is then analyzed by comparing burial tombs of other ancient Batak is also located in the region of North Padang Lawas. The Ancient tomb complex Sutan Nasinok Harahap an ancient Batak tomb and a burial place formed in a mound that is prepared and bounded by some flat stones. Burial patterns as it is also seen in the tombs of ancient Batak else in North Padang Lawas District, such as the ancient tomb of Raja Soritaon, Tuat Sohatembalon Siregar ancient tombs, and ancient tombs Lobu Dolok. Tujuan penelitian ini adalah untuk mengetahui gambaran mengenai Kompleks Makam Kuno Sutan Nasinok Harahap dan kaitannya dengan makam-makam Batak Kuno lainnya di wilayah Padang Lawas Utara. Penelitian ini menggunakan penalaran induktif yang beranjak dari data utama yang berupa Makam Kuno Sutan Nasinok Harahap, dianalisis terkait pola penguburan dengan membandingkannya dengan makam-makam Batak kuno lainnya yang juga berlokasi di wilayah Padang Lawas Utara. Kompleks makam kuno Sutan Nasinok Harahap merupakan makam Batak Kuno dan sebuah tempat penguburan, dibentuk dalam sebuah gundukan yang disusun, dibatasi oleh beberapa batu pipih. Pola penguburan seperti itu juga terlihat pada makam-makam Batak kuno lain yang ada di Kabupaten Padang Lawas Utara, seperti makam kuno Raja Soritaon, makam kuno Tuat Sohatembalon Siregar, dan makam kuno Lobu Dolok.
Analisis Pengaruh Efisiensi dan Kecukupan Modal terhadap Kinerja Keuangan pada Bank Pembangunan Daerah di Indonesia
Authors: Sparta Sparta 
Published: May 2017

<p><em>This study aims to investigate the efficiency of Indonesian regional development banks (BPD) and the effects of efficiency, capital adequacy, bank size, and macroeconomic indicators on the performance of BPDs in 2008-2012. Our variables of interests are BOPO, CAR, LNSIZE, PDRB, GCRED and INF. We analyze these variables on 130 firm-year observations using the OLS with panel data. Our findings show that on average the BOPO of our BPD sample is 72.45%. During that period, BPD Sulawesi Selatan (BPD Aceh) is the most (least) efficient BPD as indicated by its BOPO of 54.03% (92.98%). Next, our year-to-year analysis reveals that the most (least) efficient BPDs for the year 2008, 2009, 2010, 2011, and 2012 are BDKI, BSTR,BACH, BSUA, and BSSN (BSST, BSTA, BKTm, BSTA, and BSTA), respectively. Our study also indicates that none of BPD in Java have assets higher than their counterparts outside Java that are the most efficient BPDs for the whole Indonesia. Finally, we find that BOPO, CAR, LNSIZE, and GCREDR negatively affect BPDs’ financial performance while INFR is positively associated with financial performance. However, GPDRBT has no significant effect on BPDs’ financial performance.</em></p><p><em><br /></em></p><p align="center"><strong>Abstrak</strong></p><p align="center"><strong> </strong></p><p><em>Penelitian ini bertujuan untuk mengetahui gambaran efisiensi BPD di Indonesia dan pengaruh efisiensi, kecukupan modal, ukuran bank dan indikator makro ekonomi terhadap kinerja BPD di Indonesia periode 2008-2012. Variabel-variabel yang dianalisis dalam riset ini adalah BOPO, CAR, LNSIZE, PDRB, GCRED dan INF. Alat analisis yang digunakan adalah OLS dengan data panel. Jumlah observasi dalam studi ini adalah sebanyak 130. Hasil penelitian menunjukkan bahwa efisiensi bank BPD di Indonesia selama periode 2008-2012, yang ditunjukkan oleh rata-rata BOPO, adalah 72,45 persen. Selama periode tersebut, BPD Aceh mendapat predikat bank paling tidak efisien dengan BOPO 92,98 persen dan BPD Sulawesi Selatan mendapat predikat bank BPD paling efisien dengan BOPO 54,03 persen. Bank BPD paling efisien untuk tahun 2008, 2009, 2010, 2011 dan 2012 berturut adalah BDKI, BSTR, BACH, BSUA dan BSSN. Sedangkan bank BPD paling tidak efisien untuk tahun 2008, 2009, 2010, 2011, dan 2012 berturut-turut adalah BSST, BSTA, BKTm, BSTA dan BSTA. Hasil penelitian ini menunjukkan bahwa tidak ada satupun bank BPD di pulau jawa yang memiliki total aset lebih besar dibandingkan bank BPD di luar jawa yang mendapatkan predikat bank BPD paling efisien di Indonesia. Hasil penelitian ini juga menunjukkan bahwa BOPO, CAR, LNSIZE, dan GCREDR secara signifikan berpengaruh negatif pada kinerja keuangan bank BPD. INFR ditemukan berpengaruh secara signifkan dan positif terhadap kinerja keuangan BPD. Sementara itu, GPDRBT tidak memiliki pengaruh signifikan pada kinerja keuangan BPD.<br /></em></p>
Historiografias do Contemporâneo
Authors: Asbury Michael 
Published: April 2017

Desde o advento da exposição Global Conceptualisms: points of origin 1950s-1980s’, realizada no Museu de Queens, Nova York, em 1999, o termo “conceitualismo” firmou-se como o principal meio para descrever “práticas artísticas globais” de 1950 até à presente data. O termo foi se consolidando e, em grande medida ultrapassou as intenções originais da exposição para tornar-se uma forma derivativa da arte conceitual norte-americana. Tenho como hipótese de que essa relação histórica com arte conceitual é metodologicamente problemática, já que ela foi um movimento amplamente descrito como tendo surgido a partir da rejeição do formalismo greenbergiano e sua crença na especificidade dos meios. Nesse sentido, é uma denominação que é cultural, geopolítica e historicamente situada. Minha palestra terá por objetivo discutir outras terminologias possíveis para essas práticas diversas, enfatizando genealogias em que propostas de caráter conceitual surgiram sem reação direta com essa genealogia específica com a arte conceitual canônica.