bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo
Authors: Tosti Luca , Ashmore James , Tan Boon Siang Nicholas , Carbone Benedetta , Mistri Tapan K , Wilson Valerie , Tomlinson Simon R. , Kaji Keisuke 
Published: July 2017

AbstractThe identification of transcription factor (TF) binding sites in the genome is critical to understanding gene regulatory networks (GRNs). While ChIP-seq is commonly used to identify TF targets, it requires specific ChIP-grade antibodies and high cell numbers, often limiting its applicability. DNA adenine methyltransferase identification (DamID), developed and widely used in Drosophila, is a distinct technology to investigate protein-DNA interactions. Unlike ChIP-seq, it does not require antibodies, precipitation steps or chemical protein-DNA crosslinking, but to date it has been seldom used in mammalian cells due to technical impediments. Here we describe an optimised DamID method coupled with next generation sequencing (DamID-seq) in mouse cells, and demonstrate the identification of the binding sites of two TFs, OCT4 and SOX2, in as few as 1,000 embryonic stem cells (ESCs) and neural stem cells (NSCs), respectively. Furthermore, we have applied this technique in vivo for the first time in mammals. Oct4 DamID-seq in the gastrulating mouse embryo at 7.5 days post coitum (dpc) successfully identified multiple Oct4 binding sites proximal to genes involved in embryo development, neural tube formation, mesoderm-cardiac tissue development, consistent with the pivotal role of this TF in post-implantation embryo. This technology paves the way to unprecedented investigations of TF-DNA interactions and GRNs in specific cell types with limited availability in mammals including in vivo samples.
The leaders’ emotional intelligence
Authors: Dartey-Baah Kwasi , Mekpor Benjamin 
Published: July 2017

PurposeThe purpose of this paper is to determine the extent to which leaders’ emotional intelligence (EI) predict the voluntary work behaviors (i.e. organizational citizenship behavior (OCB) and counterproductive workplace behavior (CWB)) of employees in the Ghanaian banking sector.Design/methodology/approachQuantitative approach was adopted to collect data from 234 respondents working in both high- and low-performing banks in Ghana. Both purposive and simple random sampling techniques were used for the selection of the respondents.FindingsThe findings of the study revealed that the leaders’ EI positively predicted the OCB of employees while a negative relationship was found between leaders’ EI and its prediction of employees’ CWB. Thus, emotionally intelligent leaders are able to evoke citizenship behaviors while mitigating CWBs of employees in the Ghanaian banking sector.Research limitations/implicationsThe research addresses the gap in literature on how leaders’ EI influence employees’ tendency to exhibit either OCB or CWB specifically in the Ghanaian context.Practical implicationsThe findings suggest that organizational leaders especially in the Ghanaian banking sector should be trained to be emotionally intelligent in their relationship with employees as such skills boost positive voluntary behaviors and have the tendency to alleviate the negative behaviors by employees.Originality/valueThe study provides an in-depth account on how the leaders’ EI influence both employees’ OCB and CWB and how to appropriately evoke or alleviate them, respectively.
The use of big data in corporate communication
Authors: Wiencierz Christian , Röttger Ulrike 
Published: July 2017

Purpose
The purpose of this paper is to illustrate the current state of research on the significance of big data in and for corporate communication and to introduce a framework which provides specific connecting points for future research. This is achieved by summarizing and reviewing the insights provided by relevant articles in the most significant scholarly journals. The paper also investigates trends in the literature.

Design/methodology/approach
On the basis of a systematic literature review, 53 key articles from 2010 to 2015 were further analyzed.

Findings
The literature review illustrates the potentialities of big data for corporate communication, especially with regard to the field of marketing communication. It also reveals a dramatic lack of research in the fields of public relations and internal communication with respect to big data applications.

Research limitations/implications
The online databases used in this paper comprised of refereed scientific journals with the highest impact factor in the respective disciplines. Journals with a lower impact factor and books were not included in the search process for this thematic analysis.

Practical implications
This paper provides a conceptual framework that describes four phases of strategic big data usage in corporate communication. The results show how big data is able to highlight stakeholders’ insights so that more effective communication strategies can be created.

Originality/value
This paper brings together previously disparate streams of work in the fields of communication science, marketing, and information systems with respect to big data applications in corporate communication. It represents the first attempt to undertake a systematic and comprehensive interdisciplinary overview of this kind.
CEO communication: engagement, longevity and founder centrality
Authors: Conte Francesca , Siano Alfonso , Vollero Agostino 
Published: July 2017

PurposeThe purpose of this paper is to analyse the engagement of chief executive officers (CEOs) in corporate communication and focus on how their approach to communication develops in relation to the longevity of their tenure. The paper also explores how founder centrality is linked to the objectives of CEO communication and the CEOs’ use of personal social media.Design/methodology/approachThe paper brings together the relevant literature from different disciplines, related to leadership communication, CEO longevity and founder centrality, and reveals a number of unexplored issues. Four research questions were defined and an exploratory survey was carried out, involving 93 CEOs from large companies located in Italy.FindingsThe results show that CEOs are strongly engaged in institutional communication. Short-tenured CEOs seem more engaged in building and consolidating relationship networks with specific stakeholders (customers and employees), while long-tenured CEOs tend to be more involved in institutional and financial communications.Research limitations/implicationsDue to the exploratory research design and the circumscribed sample from a single country (Italy), further cross-national evidence is needed to substantiate the suggested links between engagement in communication activities and longevity. The study highlights the managerial and communication skills that CEOs must be provided with during their corporate tenure, thus suggesting the need to further examine the “life cycle” of CEO communication activities.Originality/valueThe paper sheds light on CEO communication dynamics. It is the first of its kind in the Italian context, where some factors, such as longevity of tenure, seem to play an important role in shaping corporate communication objectives and activities.
Explicating the information vacuum: stages, intensifications, and implications
Authors: Woon Eugene , Pang Augustine 
Published: July 2017

Purpose
Information vacuums (IVs) arise from organizational failure to satisfy the stakeholders’ informational demands during crises. The purpose of this paper is to expand Pang’s (2013) study of the phenomenon of IV by investigating its nature, stages, intensifying factors and resolution.

Design/methodology/approach
Print and social media data of five recent international crises with apparent IVs were analyzed.

Findings
Poor crisis communications are intensifying factors that induce media hijacks and hypes, distancing, and public confusion. A four-stage model maps the phenomenon into a flow chart describing its development. IV termination begins when organizations either respond with information or provide solutions, results, and/or compensation. Natural and strategic silence were observed and defined.

Research limitations/implications
The study lays the foundation for future examination of how media literacy, governments, and culture, both societal and organizational, induce or exacerbate the phenomenon.

Practical implications
Immediate, adequate, transparent, credible, and consistent crisis responses manage the IV and crisis, diminish the intensification of subsequent crises, and potentially reduce image and reputational damages.

Originality/value
The knowledge of the phenomenon is further developed and new theoretical models are conceptualized to provide researchers and practitioners a clearer understanding of how an IV can develop, persist, deepen, and resolve.
A cross-cultural perspective on relational exchange
Authors: Jukka Minna , Andreeva Tatiana , Blomqvist Kirsimarja , Puumalainen Kaisu 
Published: July 2017

PurposeThis study aims to examine relational norms in cross-cultural business settings. Cross-cultural business partners may differ in their normative orientations toward relational exchange. Owing to the high extent of international trade, there is a need for developing a more nuanced understanding of cross-cultural relational exchange.Design/methodology/approachThe repertory grid method was used to elicit the personal constructs characterizing the perceptions of business-to-business (B2B) relational exchange for 22 Russian and Finnish managers. These items were further categorized into categories of relational elements drawn from relational exchange literature using a content analysis. Then, the category means of scored importance and scored evaluations of domestic and foreign business partners were tested statistically.FindingsRelational norms of flexibility, information exchange, long-term orientation, mutuality and solidarity were equally important to both Russian and Finnish managers. The importance of a business partner’s ability seems to be culturally dependent. Sharing the same cultural background might have an adverse effect when evaluating poorly functioning business relations.Research limitations/implicationsThe validity of these findings is limited to this context and material. Future research should repeat cross-cultural comparisons of the relational norms with more data and other nationalities.Practical implicationsFirms should focus on long-term orientation and mutual targets to form well-functioning cross-cultural business relationships.Originality/valueThis study provides new knowledge into B2B marketing literature by revealing the role of relational norms, business partner’s ability and shared cultural background on functionality of cross-cultural business relations. It also demonstrates the use of the repertory grid method in studying perceptions of relational norms.
Does an own-brand produce higher profitability? Evidence from Taiwan’s manufacturing firms
Authors: Yang Chih-Hai , Tsou Meng-Wen 
Published: July 2017

Purpose
This study aims to investigate the determinants of own-branding strategy and whether branding contributes to higher profitability among industrial firms. Building a strong brand can be a source of competitive advantage. However, brands may not be equally important to all firms, especially in the business-to-business (B2B) context.

Design/methodology/approach
This study develops and empirically tests a conceptual model by considering the endogenous choice of branding strategy in the relationship between branding and financial performance. A large, nationally representative dataset from Taiwan, consisting of 13,098 manufacturing firms, is used.

Findings
The present study suggests that larger, younger, more innovative and export-oriented firms have a higher propensity to develop their own brands. E-commerce usage is shown to be the strongest predictor of the decision to brand. The positive effect of branding on profitability is evident for small- and medium-sized enterprises (SMEs), but not for large firms.

Originality/value
Research integrating the perspectives of the decision to brand and branding effectiveness is scant. The methodology used in this study makes a theoretical contribution to the link between branding and firm performance. The findings indicate that large firms have more advantages for building their own brands, yet SMEs stand to gain more financially from branding relative to their large counterparts. This provides the important implication that SMEs benefit from building a strong brand in the B2B context.
Information technology and performance in industrial business relationships: the mediating effect of business development
Authors: Lindh Cecilia , Rovira Nordman Emilia 
Published: July 2017

Purpose
The study addresses a gap in research concerning the specific purpose of information technology (IT) in business relationships and how it impacts business development and relationship performance. To fill this gap, the purpose of this study is to investigate the prospective effects of IT on business development and relationship performance in the business relationships of industrial firms.

Design/methodology/approach
Building on previous research from the industrial business relationship field, 353 relationships between Swedish industrial firms and their customers are analyzed with linear structural relations in LISREL.

Findings
The findings show that the effect of IT on relationship performance is not direct but mediated by business development measured in terms of business creation and product development.

Research limitations/implications
The study’s results imply that IT that is integrated in inter-firm operations has to be assigned a specific purpose to effectively influence relationship-specific performance. The results also indicate that more research is needed to provide additional insights about the relation between IT and performance in business relationships.

Social implications
If the full potential of IT-based solutions could be reached, then this could lead to the generation of new products and technologies and more competitive companies, which in turn would create more jobs and greater wealth.

Originality/value
In conclusion, this study fills a gap in research by highlighting that IT studied with a business relationship approach is particularly important under certain conditions. As such, the study contributes to the research stream seeking to understand the role of IT in industrial marketing and how IT should be used for increasing relationship performance.
Can salesperson guilt lead to more satisfied customers? Findings from India
Authors: Gabler Colin B. , Agnihotri Raj , Itani Omar S. 
Published: July 2017

PurposeThe purpose of this paper is to investigate guilt proneness as a prosocial salesperson trait and its impact on outcomes important to the firm, the customer as well as the salesperson. Specifically, the authors look at how this variable relates to job effort and the indirect effects on customer satisfaction. The corollary purpose is to uncover how managers influence these constructs through positive outcome feedback.Design/methodology/approachProsocial motivation theory grounds the conceptual model which the authors test through survey implementation. The final sample consisted of 129 business-to-business (B2B) salespeople working across multiple industries in India. Latent moderated structural equation modeling was utilized to test the proposed model.FindingsThe results suggest that guilt proneness positively influences the likelihood that a salesperson adopts a relational orientation, which has a direct effect on individual effort and an indirect effect on customer satisfaction. Supervisors have the ability to amplify this effort through positive outcome feedback, but only when relational orientation is low. Their support had no effect on salespeople with a high relational orientation.Originality/valueThe study is unique in that it combines an overlooked prosocial trait with a B2B Indian dataset. We provide value for firms because our results show that guilt-prone salespeople put more effort into their job – ”something universally desirable among sales managers” – through the development of a relational orientation. The authors also give practical implications on how to support salespeople given their level of relational orientation.
The impact of customer knowledge and marketing dynamic capability on innovation performance: an empirical analysis
Authors: Falasca Mauro , Zhang Jiemei , Conchar Margy , Li Like 
Published: July 2017

Purpose
This paper aims to explore the intermediary role of marketing dynamic capability (MDC) in the relationship between customer knowledge management (CKM) and product innovation performance (PIP).

Design/methodology
A conceptual model is proposed and a survey instrument is developed. The model is tested empirically in an organizational buyer/seller setting using a survey among middle and top management of firms engaged in business-to-business relationships within high-tech industries in China.

Findings
Results show that MDC fully mediates the relationship between CKM and PIP. Empirical findings thus demonstrate that CKM is related to improved firm PIP through the deployment of firm-specific MDCs.

Research implications/limitations
The study provides clarification for a unique distinction between organizational learning and dynamic capabilities. Findings suggest that knowledge creation occurs within the scope of CKM, while the analytical and perceptual processes that lead to insights and redeployment of firm resources fall under the umbrella of MDCs.

Practical implications
Dynamic capabilities play an essential role in transforming the firm’s knowledge resources to create new configurations in response to market needs. Hence, this study reinforces the role of marketing decision-makers with appropriate decision-making power who, in an ongoing cooperation with other functional areas, are able to adapt and redeploy resources to reflect environmental changes and implement marketing strategy decisions.

Originality/value
This study contributes to the literature by addressing simultaneously the relationship between CKM, MDC and PIP. Specifically, the study demonstrates the mediating influence of MDCs on the relationship between CKM and firm PIP. The study also clarifies a key distinction between organizational learning and dynamic capabilities, demonstrating that knowledge serves an antecedent role to the deployment of dynamic capabilities.
Culture as a moderator of cognitive age and travel motivation/perceived risk relations among seniors
Authors: Le Serre Delphine , Weber Karin , Legohérel Patrick , Errajaa Karim 
Published: July 2017

Purpose
This study contributes to greater understanding of the senior market and the cultural differences regarding aging in Western and Asian cultures. The review of the literature highlights the cultural differences toward the concept of aging in Asian and Western countries and describes a useful age concept for investigating senior consumers, namely, that of subjective age. The purpose of this study is to investigate the influence of subjective age dimensions on seniors’ behavior and to assess the role of culture as a moderator of this influence.

Design/methodology/approach
Data were collected in France and Mainland China and consisted of answers to 300 questionnaires for the French seniors and 264 questionnaires for the Chinese seniors. Two dimensions of subjective age were measured: cognitive age and ideal age, along with travel motivations and travel perceived risk.

Findings
The study provides valuable information regarding the Western and Asian senior markets. Subjective age dimensions prove to be related with seniors’ behaviors (perceived travel risks). The present study also demonstrates that nationality has a moderating role on this relation. This theoretical contribution will have to be confirmed by other studies in Asian and Western countries; it opens the door to new research on Chinese/Asian seniors involving these age variables.

Originality/value
The study gives academics and managers insights on the influence of subjective age on seniors’ behaviors in European and Asian cultural contexts.
Attitudinal determinants of environmentally sustainable behavior
Authors: Paswan Audhesh , Guzmán Francisco , Lewin Jeffrey 
Published: July 2017

Purpose
This study aims to focus on people’s pro-environmental behavior and investigates its dimensions and determinants. As environmental sustainability attracts increased scrutiny, understanding end consumers’ pro-environmental behavior becomes imperative for various stakeholders in our highly networked marketplace – e.g. policymakers, businesses, consumers, the public and society at large.

Design/methodology/approach
Using data from the general public in the USA, the hypothesized relationships are tested using structural equation modeling (SEM).

Findings
The results indicate that if people find enjoyment in nature, believe in achieving a balance between “mankind” and nature, and believe that the benefits of conservation activities are going to accrue in the near term (present), they are more likely to engage in pro-environmental behavior at all levels – supportive, active and lifestyle.

Research limitations/implications
Although only one aspect of environmental sustainability – environmental conservation – is analyzed, these findings support assertions set forth in the theory of environmentally significant behavior (Stern, 1999), the norm-activation theory of altruism (Schwartz, 1973), the theory of reasoned action (Fishbein, 1979) and the theory of planned behavior (Ajzen, 1985).

Practical implications
Messages about sustainability, environmental conservation and pro-environmental behavior should be framed using people’s fondness for and enjoyment of nature; should focus on present benefits of conservation; and should be targeted and differentiated for men, women and older people to encourage conservation behaviors among these differing demographic groups.

Originality/value
This study identifies three different levels of intensity of pro-environmental behavior – supportive, active and lifestyle – and empirically examines the relationships between these behavior types and the attitudinal antecedents revolving around time when the benefits of environmental conservation accrue, nature and human–nature interaction.