bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using reflection and dialog feedback to promote the development of situated and dynamic pedagogical content knowledge
Authors: Li Xijuan , Li Fangfang , Chen Xiaoge , Wang Lei 
Published: October 2024

AbstractThis study explores the reflection and dialog feedback of preservice teachers (PTs) in a one-semester chemistry teaching design and practice course with the aim of improving their situated and dynamic pedagogical content knowledge (PCK). Using a collective case study method, reflections and dialogs from 18 PTs across six teaching cycles were analyzed. The research results indicate that teaching reflection focuses on five themes: the diversity of student situations, the functionality of teaching contexts, the consistency of teaching content, the construction of teacher‒student dialog, and the progression of subject practice activities. The reflection of the PTs strengthened meaningful teaching content and corresponding specific skills, and effective dialog feedback provided external evaluation standards. The reflection prompted teachers to evaluate from multiple perspectives and levels and provided important insights to promote the development of situated and dynamic PCK. This study concludes with a discussion of the practical implications and potential for future research to develop a situated and dynamic PCK for PTs.
Relationship between internet and smartphone addiction and eating attitude and feelings of loneliness in young and adults
Authors: Sanlier Nevin , Özyalçin Büşra , Kocabaş Şule , Ercan Şeyma Nur 
Published: October 2024

Abstract
Background
The developing technology and the rapid increase in the use of the internet, smartphones, and mobile applications can disrupt the daily quality of life of individuals. This research aimed to scrutinize the link between the internet and smartphone addiction of individuals, eating attitude, and loneliness status. This research was carried out in Ankara, Turkey, and cross-sectional study. A total of 643 (M = 240, F = 403) volunteers between the ages of 18 and 50 participated in the study. Eating Attitude Test (EAT-26), Young Internet Addiction Test (YIAT), Smartphone Addiction Scale (SAS), and UCLA Loneliness Scales were used in this study.

Results
As the age of the participants increased, YIAT (r =  − 0.352, p < 0.01), SAS scale (r =  − 0.302, p < 0.01), and UCLA questionnaire scores (r =  − 107, p < 0.01) decreased. When BMI of individuals increas, YIAT (r =  − 0.163, p < 0.01), and SAS scale (r =  − 0.173, p < 0.01) scores decrease. As a result of logistic regression multiple analysis, the odds ratio (OR) and 95% confidence interval (95% CI) values for the risk of abnormal eating attitudes were 1.654 (1.166–2.607) in overweight and 2.257 (1.466–3.477) in smartphone addiction (p < 0.05).

Conclusions
According to the results of this study, it can be put forth that smartphone and internet addiction is associated with abnormal eating attitude and loneliness.
Relationship between locus of control and health-related quality of life in chronic stroke patients: a cross-sectional study
Authors: Vasu Deepak Thazhakkattu , Pang Yui Gi 
Published: October 2024

Abstract
Introduction
Stroke is a major cause of disability in adults and the elderly worldwide. Post-stroke rehabilitation success largely depends on consistent participation in treatment sessions and adherence to prescribed physical exercises; however, factors such as individual belief about their health status often affect motivation, slowing recovery. Addressing these influences is essential for improving health-related quality of life and optimizing recovery outcomes.

Methods
This study employed a cross-sectional and correlational design with convenience sampling. The aim was to explore the relationship between recovery locus of control (RLOC) and health-related quality of life (HRQoL) among chronic stroke survivors. The Recovery Locus of Control scale and the EuroQol 5D-5L scale were utilized for assessment.

Results
A total of 69 participants were included in this survey. The mean RLOC score was 34.91, with internal RLOC at 21.16 and external RLOC at 13.77 and the total EQ5D index was 0.659. Age was a significant grouping factor, with the 30–39 age group showing a significant positive relationship (r = 1.000, p = 0.002), pain and anxiety/depression (p = .045), mobility and anxiety/depression (p = .009), anxiety/depression and self-care (p = .047), IRLOC and ERLOC (p = .013).

Conclusion
The study found that while respondents exhibited high RLOC scores, there was no significant relationship between RLOC scores and the EQ5D-5L index score, suggesting that other factors may play a more critical role in influencing HRQoL among chronic stroke survivors.
GDF15 Knockout Does Not Substantially Impact Perinatal Body Weight or Neonatal Outcomes in Mice
Authors: Mulcahy Molly C , El Habbal Noura , Redd JeAnna R , Sun Haijing , Gregg Brigid E , Bridges Dave 
Published: October 2024

Abstract
Growth differentiation factor-15 (GDF15) increases in circulation during pregnancy and has been implicated in food intake, weight loss, complications of pregnancy, and metabolic illness. We used a Gdf15 knockout mouse model (Gdf15−/−) to assess the role of GDF15 in body weight regulation and food intake during pregnancy. We found that Gdf15−/− dams consumed a similar amount of food and gained comparable weight during the course of pregnancy compared with Gdf15+/+ dams. Insulin sensitivity on gestational day 16.5 was also similar between genotypes. In the postnatal period, litter size and survival rates were similar between genotypes. There was a modest reduction in birth weight of Gdf15−/− pups, but this difference was no longer evident from postnatal day 3.5 to 14.5. We observed no detectable differences in milk volume production or milk fat percentage. These data suggest that GDF15 is dispensable for changes in food intake, and body weight as well as insulin sensitivity during pregnancy in a mouse model.
Liraglutide for the Treatment of Severe Hypoglycemia Following Total Pancreatectomy and Islet Autotransplantation
Authors: Chan Christopher , Hawthorne Wayne , Pleass Henry , Holmes-Walker Deborah Jane 
Published: October 2024

Abstract
Total pancreatectomy and islet autotransplantation (TPIAT) is an effective treatment for chronic and recurrent acute pancreatitis, and it provides a significant potential additional benefit of insulin independence. Spontaneous hypoglycemia in the absence of insulin therapy following TPIAT is a recognized complication, which has been attributed to lack of protective glucagon responses to hypoglycemia, following intrahepatic islet autotransplantation. We describe the use of liraglutide to treat spontaneous hypoglycemia following TPIAT. Continuous glucose monitoring was used to identify timing of hypoglycemia in relation to meals and monitor treatment effect. Liraglutide has been used for management of hypoglycemia following bariatric surgery, but, to our knowledge, this is the first application of its effective use to treat spontaneous severe hypoglycemia following TPIAT.
Juvenile Hemochromatosis Connecting Cardiac Arrest and Hypogonadotropic Hypogonadism in a Young Woman
Authors: Zinecker Kevin Alexander , Sliwinska Aleksandra , Wilson Leah M , Zahr Roula 
Published: October 2024

Abstract
Juvenile hemochromatosis (JH) is a subtype of hereditary hemochromatosis, a genetic disorder characterized by excessive iron absorption and deposition in various organs, leading to cardiomyopathy, cirrhosis, and diabetes. Endocrine dysfunction is a common manifestation and may appear years before end-organ damage. This report describes a rare case of JH, emphasizing the consequences of delayed diagnosis. A 28-year-old woman with a history of hypogonadotropic hypogonadism presented with cardiac arrest complicated by acute renal failure and cerebral vascular accidents. She initially exhibited signs of severe cardiomyopathy and multiorgan failure, which led to workup for an underlying cause. Laboratory values showed significantly elevated ferritin and transferrin saturation. Subsequent genetic screening revealed HJV gene pathogenic variants consistent with juvenile hemochromatosis. Treatment involved aggressive iron chelation therapy and outpatient referral for cardiac transplant. This case calls for heightened awareness and early screening of JH, particularly among patients with unexplained endocrine dysfunction. Early diagnosis and treatment are paramount in preventing irreversible organ damage and improving patient outcomes.
Awake Supraglottic Airway Placement in Pediatric Patients for Airway Obstruction or Difficult Intubation: Insights From an International Airway Registry (PeDI)
Authors: Longacre Mckenna , Park Raymond S. , Staffa Steven J. , Rowland Matthew J. , Meserve Jonathan , Lord Charles , Templeton T. Wesley , Garcia-Marcinkiewicz Annery G. , Peyton James M. , Fiadjoe John E. , Kovatsis Pete G. , Stein Mary Lyn ,   the PeDI Collaborative Investigators
Published: October 2024

BACKGROUND:
Small case series have described awake supraglottic airway placement in infants with significant airway obstruction and difficult intubations. We conducted this study to determine outcomes when supraglottic airways were placed in awake children enrolled in the international Pediatric Difficult Intubation Registry including success of ventilation, success of tracheal intubation, and complications.

METHODS:
We reviewed the Pediatric Difficult Intubation Registry to identify all cases of awake supraglottic airway placement before planned tracheal intubation from August 2012 to September 2023 with subsequent review of details of awake supraglottic airway placement in the medical record. We present descriptive statistics of patient demographics, ventilation and intubation outcomes, and complications.

RESULTS:
A supraglottic airway was placed in an awake child in 95 of 8061 (1.2%) cases in the Pediatric Difficult Intubation Registry. Median age was 37 days (range 0–17.6 years) and median weight was 3.7 kg (1.6–46.7 kg). Sixteen (17%) cases were in patients older than 2 years and 7 (7%) were in adolescents. Adequate ventilation via a supraglottic airway was achieved in 81/95 (85%, 95% confidence interval [CI], 77%–93%) encounters. Inadequate (n = 13) or impossible (n = 1) ventilation occurred in 14/95 (15%). No complications were reported with supraglottic airway placement. For subsequent intubation, there was a 35% (33/95) first-attempt success rate and 99% (94/95) eventual success, with 1 patient awakened after failed attempts at tracheal intubation. Hypoxia occurred during the first intubation attempt in 9/95 (9%) encounters. The incidence of hypoxia was lower in encounters in which ventilation via the supraglottic airway was adequate (4/81, 5%) than in encounters in which ventilation via the supraglottic airway was inadequate or impossible (5/14, 36%).

CONCLUSIONS:
Although infrequently attempted, awake placement of a supraglottic airway in children with difficult airways achieved adequate ventilation and provided a conduit for oxygenation and ventilation after induction of anesthesia across a spectrum of ages.
Hindlimb kinematics, kinetics and muscle dynamics during sit-to-stand and sit-to-walk transitions in emus (Dromaius novaehollandiae)
Authors: Lin Yuting , Rankin Jeffery W. , Lamas Luís P. , Moazen Mehran , Hutchinson John R. 
Published: October 2024

ABSTRACT
Terrestrial animals not only need to walk and run but also lie prone to rest and then stand up. Sit-to-stand (STS) and sit-to-walk (STW) transitions are vital behaviours little studied in species other than humans so far, but likely impose biomechanical constraints on limb design because they involve near-maximal excursions of limb joints that should require large length changes and force production from muscles. By integrating data from experiments into musculoskeletal simulations, we analysed joint motions, ground reaction forces, and muscle dynamics during STS and STW in a large terrestrial, bipedal and cursorial bird: the emu (Dromaius novaehollandiae; body mass ∼30 kg). Simulation results suggest that in both STS and STW, emus operate near the functional limits (∼50% of shortening/lengthening) of some of their hindlimb muscles, particularly in distal muscles with limited capacity for length change and leverage. Both movements involved high muscle activations (&gt;50%) and force generation of the major joint extensor muscles early in the transition. STW required larger net joint moments and non-sagittal motions than STS, entailing greater demands for muscle capacity. Whilst our study involves multiple assumptions, our findings lay the groundwork for future studies to understand, for example, how tendon contributions may reduce excessive muscle demands, especially in the distal hindlimb. As the first investigation into how an avian species stands up, this study provides a foundational framework for future comparative studies investigating organismal morphofunctional specialisations and evolution, offering potential robotics and animal welfare applications.
Socjologia epidemii. Wyłaniające się choroby zakaźne w perspektywie nauk społecznych
Authors: Afeltowicz Łukasz , Wróblewski Michał 
Published: October 2024

Epidemics of infectious diseases are also social phenomena. Taking into consideration social, cultural, and political factors is important while explaining why a disease spreads and also while considering how to slow it down or stop it. This applies not only to diseases known for centuries, such as plague, tuberculosis, and cholera, but also to those that have emerged more recently, such as HIV/AIDS, Ebola, swine flu, and COVID-19. This work is a guide to the social aspects of epidemics. It shows the role that pathogens have played in the development of human civilisations, the relationship between epidemics and modernity, and why the late modern world encourages the emergence of new infectious threats. The book shows how pathogens have been made a significant element of various policies and what impact epidemics have had on the concept of public health. It also discusses how infectious diseases are presented in popular culture and analyses the mechanisms of collective and institutional responses to the threat associated with them. Finally, the book presents the results of studies from 2018 and 2020 on the attitudes of Polish women and men towards infectious diseases and their attitudes towards the pandemic. All this means that this work allows us to put the scale of our response to COVID-19 in the right perspective. Interview with Prof. Michał Wróblewski:
Development and evaluation of a free-form-based optical antenna with enhanced channel performance
Authors: Peng Xing , Shen Xiao , Liao Rongjie 
Published: October 2024

Optical receiving antennas play a pivotal role in enhancing the communication quality of visible light communication (VLC) systems. In this study, we propose an innovative optical receiving antenna based on free-form surfaces. Initially, the layout scheme for the LED array is meticulously optimized to ensure uniform indoor illumination. Subsequently, a three-piece integrated optical receiving antenna is designed using XY polynomial free-form surfaces with the primary objectives of amplifying the optical gain, augmenting the received power, and elevating the signal-to-noise ratio (SNR). To further validate the efficacy of the proposed optical receiving antenna, an indoor VLC channel model is established, and its performance is rigorously analyzed. Experimental outcomes reveal that the mean square error of indoor illumination stands at 113.3 lx, the optical gain of the free-form optical receiving antenna reaches an impressive 11.29, the semiregular field of view spans 35.2°, the average received power amounts to 6.1251 dBm, the average SNR attains 84.7054 dB, and the radius of the optical spot is a mere 1.5 mm. Consequently, the optimized free-form optical receiving antenna can guarantee high-speed and stable communication within indoor VLC systems, thereby furnishing crucial technical support for the advancement of VLC communication technology.
A scoping review of substance use brief interventions in Africa
Authors: Jaguga Florence , Kiburi Sarah Kanana , Temet Eunice , Aalsma Matthew C. , Ott Mary A. , Maina Rachel W. , Wachira Juddy , Mostert Cyprian , Kosgei Gilliane , Tenge Angeline , Atwoli Lukoye 
Published: October 2024

Background
The burden of substance use in Africa is substantial. Brief interventions (BIs) are a recommended public health strategy for the prevention and early intervention for substance use problems. The objective of this scoping review was to map the literature on substance use BIs in Africa, identify gaps, and provide directions for future research.

Methods
The scoping review was guided by the Arksey O’Malley Framework and the PRISMA-Scoping review (PRISMA-ScR) guidelines. A search of five bibliographic databases (PubMed, PsychINFO, Web of Science, Cumulative Index of Nursing and Allied Professionals (CINAHL) and Cochrane Library) was conducted from inception until 1st November 2023. BIs were defined as those targeting substance use and delivered over 1–4 sessions, or interventions delivered over more than four sessions if the authors referred to them as ‘brief’. Results of the review have been summarized descriptively and organized by three broad outcomes: BI effect and feasibility; feasibility and effectiveness of training providers to deliver BIs; Other outcomes i.e. cost-effectiveness, BI adaptation and development, and knowledge attitude and practice of BIs by providers.

Results
Of the 80 studies that were eligible for inclusion, 68 investigated the effect and feasibility of BIs, six studies investigated the feasibility and effectiveness of training providers to deliver BIs, and six explored other outcomes. Most of the available studies had been conducted in Eastern and Southern Africa. BIs were largely based on motivational interviewing and psychoeducational principles. Overall, the BIs were reported as feasible to implement from the perspective of policy makers, providers, and the intervention recipients. Findings on the effect of BIs on substance use were mixed. Key evidence gaps emerged. There was paucity of BI research focusing on substances other than alcohol, and there was limited literature on feasibility and efficacy of BIs among youth and adolescents.

Conclusion
The results of this scoping review provide important directions for future substance use BI research in Africa.
Mutational analysis of cytoplasmic domain of integrin subunit alpha-1 and its association with periapical wound healing after surgical endodontic treatment
Authors: Ghazal Tuba , Ahmed Muhammad Adeel , Qazi Fazal-ur-Rehman , Haider Muhammad Mohsin , Naeem Sana , Jouhar Rizwan , Umer Muhammad Farooq , Faheemuddin Muhammad , Jasthi Veeriah Chowdary , Mughal Nouman 
Published: October 2024

Background
Numerous studies reported that the healing after surgical endodontic retreatment is influenced by multiple factors which include the genetic profile of the patient, epigenetics, and immune responses. The genes which are primarily responsible for the healing potential in different individuals are those which are involved in the regulation of the cytoskeleton and cellular adhesion which subsequently affects bone deposition and healing. Integrins are cell-surface molecules, possess a key role in the cytoskeleton and cellular adhesion. Integrin Subunit Alpha 1 (ITGA1) is one among the integrin family and helps in regulating the Epidermal Growth Factor receptor (EGFR) pathway, consequently affects proliferation and healing. The objectives of the study were to identify mutations in the cytoplasmic domain of Integrin Subunit Alpha 1 (ITGA1), to assess the expression of activated EGFR, EGFRPhospho and TC-PTP in the periapical wound and to correlate these mutations and expression patterns with periapical wound healing.

Methods and findings
Thirty-seven patients between ages 18–60 years reported chronic apical periodontitis of single-rooted anterior teeth with periapical radiolucency, equal or greater than 4 mm or periapical lesion in an open apex of single-rooted teeth due to trauma were included in the study from 01st June 2018 till 31st October 2019. Patients with persistent radiolucency after primary root canal treatment and endodontic retreatment were kept on follow-up for 3–4 months surgical endodontic treatment was performed in cases with persistent periapical lesions of 4mm or more in diameter. Periapical lesion sample was collected and used for (1) histo-pathological analysis after Hematoxylin & Eosin staining, (2) total DNA extraction for ITGA1 cytoplasmic domain mutational analysis and immunohistochemistry for EGFR and TCPTP. A positive correlation was observed between the expression levels of EGFRPhospho and the healing of periapical lesions. Moreover, a negative weak correlation was observed between the expression levels of EGFR and TCPTP and the healing of periapical lesions. Out of nine sequences of cytoplasmic domain of ITGA1 which were analyzed, none of them was detected with SNP.

Conclusion
Higher expression levels of EGFRPhospho and lower expression levels of EGFR and TCPTP were associated with patients with good healing potential in periapical area. However, immunohistochemistry scores were statistically insignificant to draw any conclusion.