bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the associations between high achievement in reading and school climate: evidence from five South American countries
Authors: Rodríguez De Luque Jesús José 
Published: September 2024

AbstractAn emergent literature has shown that some students overcome adversities related to their low Socio-Economic Status (SES) by attaining high academic achievement. One of the aims of this literature is to identify the factors that explain the capacity of students from low SES backgrounds to attain high academic achievement. However, upon reviewing this literature, I observed that few studies have comparatively investigated the associations between the capacity of students from low SES backgrounds to attain high achievement in reading and school climate characteristics. Additionally, I found that not many studies have researched whether student SES moderates these associations. This paper contributes to fill these two gaps by estimating associations between high achievement in reading and school climate characteristics. Moreover, it examines whether student SES moderates these associations. To do this, this research estimated logit and heterogeneous choice models using representative samples of students from Argentina, Brazil, Chile, Colombia, and Uruguay who participated in the 2018 Programme for International Student Assessment (PISA). The results show that high achievement in reading is positively correlated to certain teaching practices, such as perceived teacher enthusiasm during the instruction and adapting instruction to students’ needs. Conversely, it is negatively correlated to teacher feedback and teacher-directed instruction. Furthermore, the findings indicate that high achievement in reading is negatively correlated to the scarcity and low quality of educational material. Interestingly, the results show that student SES does not moderate these associations. In conclusion, these findings indicate that interventions targeting these areas of school climate may help to increase students’ probability of attaining high achievement in reading, regardless of their SES. Likewise, these results suggest that if these interventions are focused in low SES schools, they may contribute to bridge the gap in reading skills between students from low and middle or high socioeconomic backgrounds.
Using syndromic surveillance for unintentional and undetermined intent drowning surveillance in a large metropolitan area
Authors: Shenoi Rohit P. , Moreland Briana , Jones Jennifer L. , Peoples Nicholas , Camp Elizabeth A. , Levine Ned 
Published: September 2024

Abstract
Introduction
A drowning definition is available for use with National Syndromic Surveillance Program (NSSP) data. However, its accuracy in capturing drowning emergency department and urgent care visits at the regional level is unknown. We tested the ability of the syndromic surveillance (SS) definition in capturing unintentional and undetermined intent drowning (UUID) and describe UUID SS visit trends in a large metropolitan area.

Methods
We applied the drowning definition to NSSP data from 2016 to 2022 for the 8-county metropolitan Houston region. We queried the dataset for UUID ICD-10-CM codes and manually reviewed the chief complaint (CC) and discharge diagnosis (DD) for SS visits. True-positives were calculated by dividing the number of UUID cases identified by UUID ICD-10-CM codes and CC/DD review by the total visits captured by the SS definition. Demographics and trends of UUID visits were calculated from 2018 to 2022 due to limited data from 2016 to 2017 in NSSP.

Results
2,759 visits were captured by the SS definition. After case review, 2,019 (73.2%) had ICD-10-CM drowning codes of any intent; and 2,015 of those (99.8%) were classified as UUID. Of the remaining 740 cases with no ICD-10-CM codes that were pulled by the SS definition, 690 (93.2%) had a CC/DD diagnosis of drowning/submersion/underwater related to aquatic exposure. Taken together, 2,705 (98.0%) were true-positive UUID visits based on the SS drowning definition.. Children (aged < 18 years) constituted 79% of UUID visits. Black, White and Asian/Pacific Islander persons comprised 17%, 60% and 4% of UUID visits respectively. Rates of UUID visits were lowest in 2020.

Conclusion
Syndromic surveillance is a novel and accurate method to conduct real-time drowning surveillance in a large metropolitan region.
Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases
Authors: Aswani Babu Santha , Hegde Mangala , Vishwa Ravichandran , Alqahtani Mohammed S. , Abbas Mohamed , Almubarak Hassan Ali , Sethi Gautam , Kunnumakkara Ajaikumar B. 
Published: September 2024

AbstractNuclear receptors (NRs) function as crucial transcription factors in orchestrating essential functions within the realms of development, host defense, and homeostasis of body. NRs have garnered increased attention due to their potential as therapeutic targets, with drugs directed at NRs demonstrating significant efficacy in impeding chronic disease progression. Consequently, these pharmacological agents hold promise for the treatment and management of various diseases. Accumulating evidence emphasizes the regulatory role of exosome-derived microRNAs (miRNAs) in chronic inflammation, disease progression, and therapy resistance, primarily by modulating transcription factors, particularly NRs. By exploiting inflammatory pathways such as protein kinase B (Akt)/mammalian target of rapamycin (mTOR), nuclear factor kappa-B (NF-κB), signal transducer and activator of transcription 3 (STAT3), and Wnt/β-catenin signaling, exosomes and NRs play a pivotal role in the panorama of development, physiology, and pathology. The internalization of exosomes modulates NRs and initiates diverse autocrine or paracrine signaling cascades, influencing various processes in recipient cells such as survival, proliferation, differentiation, metabolism, and cellular defense mechanisms. This comprehensive review meticulously examines the involvement of exosome-mediated NR regulation in the pathogenesis of chronic ailments, including atherosclerosis, cancer, diabetes, liver diseases, and respiratory conditions. Additionally, it elucidates the molecular intricacies of exosome-mediated communication between host and recipient cells via NRs, leading to immunomodulation. Furthermore, it outlines the implications of exosome-modulated NR pathways in the prophylaxis of chronic inflammation, delineates current limitations, and provides insights into future perspectives. This review also presents existing evidence on the role of exosomes and their components in the emergence of therapeutic resistance.
Rectum necrosis in a patient with severe COVID19 infection after CAR-T therapy: a case report
Authors: Saeki Kiyoshi , Nakagama Hidenobu , Tanaka Yuichi , Goto Yoshitaka , Kaneshiro Kazuhisa , Kono Hiroshi , Yanai Kosuke , Yamamoto Hirofumi , Yoneda Reiko , Shimakawa Takashi , Ueki Takashi 
Published: September 2024

Abstract
Background
Coronavirus disease 2019 (COVID19) can cause gastrointestinal complications as well as respiratory tract disease. Coagulation abnormalities and thrombosis frequently occur in COVID19, especially in cases with severe clinical outcome. The relationship between gastrointestinal perforation and coagulopathy due to COVID19 remains unclear.

Case presentation
A 49-year-old female received Chimeric antigen receptor T (CAR-T) therapy for an early recurrence of diffuse large B-cell lymphoma (DLBCL) that was refractory to chemotherapy. She was diagnosed with cytokine release syndrome (CRS) because of a fever and oxygen desaturation, and administered tocilizumab. Forty days after completing CAR-T therapy, she was infected with COVID19 and transferred to our hospital. Her general condition worsened and she developed COVID19 pneumonia, and then steroid pulse therapy was started. While her respiratory condition improved, she experienced pain in the anal region and computed tomography (CT) revealed a rectal perforation. An emergency surgery was undertaken, and the lower rectum wall was found to be completely necrotic. Removal of the necrotic part of the rectum tissue, and drainage and lavage of necrotic tissue in the pelvic cavity were performed. The remaining rectum was resected with partial sigmoidectomy, but we could not make the anal stump closed. In addition, an end colostomy in the sigmoid colon was performed. Histopathological findings showed thromboses in the rectal mesentery veins. After the first surgery, the pelvic abscess cavity persisted and her high-grade fever continued. Reoperation was laparoscopically performed, and she underwent a resection of anal canal with residual necrotic rectal and mesorectal tissue, and a drainage of the pelvic abscess. After the reoperation, her general condition improved and CT showed that the abscess cavity had significantly improved.

Conclusions
Gastrointestinal perforation, especially rectal necrosis due to coagulopathy caused by severe COVID19 infection, is a rare but life-threatening complication. Physicians should have a high degree of clinical suspicion for timely diagnosis and management, and surgical intervention is necessary in cases of rectal necrosis.
Upper Extremity Stress Fractures
Authors: Koslosky Ezekial J. , Heath David M. , Atkison Cameron L. , Dutta Anil , Brady Christina I. 
Published: September 2024

Abstract
Background
Stress injuries are often missed secondary to their insidious onset, milder symptoms, and subtle or initially absent findings when imaged.

Main Body
This review aims to provide strategies for evaluating and treating upper extremity stress fractures. This article outlines the classic presentation of each fracture, the ages during which these injuries often occur, the relevant anatomy and biomechanics, and the mechanism of each injury. Diagnostic imaging and management principles are also discussed, including the use of conservative versus surgical management techniques.

Short Conclusion
Upper extremity stress fractures are often mild injuries that resolve with conservative management but can lead to more serious consequences if ignored. Given their increasing incidence, familiarity with diagnosis and management of these injuries is becoming increasingly pertinent.
Characteristics of longitudinal changes in quality of life and associated factors in patients post cardiac and thoracic aortic surgery: insights from a prospective cohort study
Authors: Sato Masaaki , Mutai Hitoshi , Yamamoto Shuhei , Tsukakoshi Daichi , Furuhashi Keisuke , Ichimura Hajime , Wada Yuko , Seto Tatsuichiro , Horiuchi Hiroshi 
Published: September 2024

Abstract
Background
Although quality of life (QOL) is an outcome of postoperative cardiac rehabilitation (CR), its course and related factors from postoperative hospitalization to the post-discharge period have not been adequately investigated. Additionally, the EuroQol-5Dimension-5Level (EQ-5D-5L) index score has not been characterized over the same period. We aimed to characterize QOL changes assessed by the EQ-5D-5L, over the period from hospitalization to 1 year post-discharge, in patients post-cardiac and thoracic aortic surgery, and investigate the factors associated with these temporal changes.

Methodology
This prospective, single-center study included 117 patients who underwent open cardiovascular surgery (median age, 72 years; men, 69%). Patients were assessed for QOL status when transferred to the general ward; at discharge; and at 6 and 12 months after discharge, using the EQ-5D-5L index score and a generalized linear mixed model with random intercepts. Patients were classified into two groups based on score changes post-discharge. Logistic regression analysis evaluated factors associated with QOL decrease post-discharge.

Results
The EQ-5D-5L index score significantly increased over time, except between 6 and 12 months post-discharge; “Common activities” was the most common dimension showing score improvement. In 25 patients (21%), the EQ-5D-5L index scores were lower after discharge compared to their scores at discharge. In the logistic regression analysis, Barthel Index pre-admission, preoperative hemoglobin level, and Mini-Mental State Examination-Japanese scores pre-discharge were significantly associated with QOL decline after adjusting for the European System for Cardiac Operative Risk Evaluation II score.

Conclusions
Most patients post-cardiac or thoracic aortic surgery experienced improved QOL from postoperative hospital stay to 1 year post-discharge. However, in patients with pre-operative basic activities of daily living, hemoglobin and post-operative cognitive decline may require ongoing comprehensive CR because of reduced QOL. Given the potential selection bias introduced by the relatively small sample size in this study, future research involving larger populations is necessary.
Medical student attitudes toward mental illness: a cross-sectional study from the Gaza Strip, Palestine
Authors: Aldabbour Belal , Abu-El-Noor Nasser , Elhissi Ahmed , Wafi Jamil , Dabour Asad Mohammad , Aldabbour Osama , Abuabada Amal , Diab Abedelrahman Rizq , Abu-El-Noor Mysoon Khalil 
Published: September 2024

Abstract
Background
Mental illness is highly stigmatized compared to physical illness, often due to false beliefs and a lack of knowledge. Negative attitudes harbored by healthcare providers reflect on the care they provide and impact their patients’ outcomes and may tailor their future preferences away from the psychiatric practice. This cross-sectional study used a stratified, randomized sampling method to survey the beliefs and attitudes of students at a Palestinian medical school toward mental illness using the Beliefs Toward Mental Illness (BMI) scale.

Results
Overall, 79.1% of 282 participants demonstrated positive attitudes toward mentally ill patients (BMI score < 43). The highest mean score (more negative attitude) was received by the ‘dangerousness’ domain (2.75 ± 0.75), while the ‘poor social and interpersonal skills’ domain received the lowest mean score (2.47 ± 0.82). Male sex (p = 0.031) and having a friend (p = 0.035) or a family member (p = 0.035 and p = 0.033, respectively) suffering from a mental illness predicted a more positive attitude toward mental illness. At the same time, age, study level, and having undergone the clinical psychiatry rotation did not impact attitude significantly.

Conclusions
The study shows that medical students in the Gaza Strip are not absolved from the negative stereotypes of their community toward mentally ill patients, which should be addressed systematically by health educators and medical schools in the country.
Anti-inflammatory and anti-arthritic activities of ethanolic extract of Myxopyrum serratulum A.W. Hill
Authors: T Sheela Rani , Jeyabalan Srikanth , Dhanasekaran Sivaraman , Sekar Mahendran , Subramaniyan Vetriselvan , Wong Ling Shing 
Published: September 2024

Abstract
Background
Rheumatoid arthritis (RA) is a debilitating inflammatory disorder characterized by an overactive immune system targeting joints, leading to inflammation and intense pain. While current RA therapies effectively alleviate symptoms, they are often associated with significant side effects. This study aimed to assess the anti-inflammatory and anti-arthritic properties of an Ethanolic Extract of Myxopyrum serratulum A.W. Hill (EEMS) using animal models.

Results
The acute toxicity study with EEMS (2000 mg/kg, p.o.) on rats showed no toxicity or mortality up to the highest dose. Inflammation was induced using carrageenan, and rats were treated with varying doses of EEMS (100, 200, and 400 mg/kg, p.o.) and diclofenac to assess anti-inflammatory effects. Anti-arthritic efficacy was evaluated using Complete Freund’s adjuvant (CFA)-induced inflammation, comparing EEMS to methotrexate. The results revealed dose-dependent anti-inflammatory effects of EEMS and a reversal of arthritic-induced weight loss in treated groups. Paw volume reduction was significant in both EEMS and methotrexate groups. Biochemical analyses showed elevated markers in the arthritic control group, which were normalized by EEMS and methotrexate. Notably, EEMS (400 mg/kg) significantly reduced cathepsin-D levels compared to the positive control. EEMS administration also lowered hepatic lipid peroxidation and increased endogenous antioxidants (SOD, GSH, and GPX). The 200 and 400 mg/kg doses reduced the iNOS/GADPH ratio, while the 400 mg/kg dose restored cellular and joint structure and significantly decreased IL1 levels.

Conclusions
In conclusion, EEMS demonstrated substantial protective effects, mitigating health risks associated with chronic inflammation such as arthritis. These findings underscore the ethnomedical potential of Myxopyrum serratulum as a promising anti-inflammatory and anti-arthritis agent. The study suggests that EEMS could be a viable alternative or complementary therapy for RA, offering therapeutic benefits with potentially fewer side effects than current treatments.
Fermion behavior around Sung-Won Kim wormholes in a generalized Kaluza-Klein gravity
Authors: Cavalcante Everton 
Published: September 2024

Abstract
This paper investigates the behavior of fermions in the vicinity of Sung-Won Kim wormholes (Kim
S.-W., Phys. Rev. D, 53 (1996) 6889) within the framework of a generalized Kaluza-Klein gravity. The study explores the geometric and quantum implications of introducing an extra dimension into the Sung-Won Kim wormhole model. The impact of this additional dimension on the stability and traversability of the wormholes, as well as on the fermionic equations of motion, is analyzed. By examining the modified Dirac equation in this extended framework, the emergence of geometric phases and quantum holonomies is discussed, providing insights into the topological aspects of fermion dynamics in curved spacetimes.
“This Is Not a Performance”: Coming-Out Videos, LGBTQ+ Microcelebrity, and the Tenuous Rise of New Queer YouTube
Authors: O'Gara Clare 
Published: September 2024

Abstract
This article uses three coming-out YouTube videos to narratively map the emergence of “New Queer YouTube,” a phrase used in this article to describe the evolving tactics and styles deployed by LGBTQ+ microcelebrity YouTubers over the previous decade. Encapsulated by Ingrid Nilsen's 2015 YouTube video “Something I Want You to Know (Coming Out),” 2010s-era coming-out videos represent early attempts to reconcile authentic queer disclosure with the performative conditions of microcelebrity. In the 2020s era, coming-out videos and queer YouTubers frequently acknowledge and elevate this legacy with an aesthetic that evokes the postmodern sensibilities of New Queer Cinema and “post-Stonewall” queer documentaries. Two videos are of particular interest here: Natalie Wynn's “Shame | ContraPoints,” and Abigail Thorn's “Identity: A Trans Coming Out Story | Philosophy Tube ★.” While the creators of these texts declare authentic queer identities to their audiences, they pursue different approaches that nonetheless tangle personal confession with performance. These videos and their respective microcelebrity personas wield coming-out and LGBTQ+ embodiment as devices to simultaneously claim agency over a queer identity and, ultimately, enhance perceived authenticity through the revelation of performance and the reflexive rebirth of digital persona. These strategies exemplify an aesthetic of queer, postmodern YouTube microcelebrity necessitated, in part, by the site's increasing stratification and precarity as a meaningfully user-generated platform.
Association of dysphagia and loneliness and their interaction with sleep quality among older adults in nursing homes: A cross-sectional study
Authors: Wen Bihan , Li Yao , Zhang Mengyao , Xu Huilan 
Published: September 2024

Objective
Poor sleep quality is a risk factor for many adverse health outcomes and has become a widespread and serious public health problem, especially among older adults. This study aimed to explore the association between dysphagia, loneliness, and their interaction with sleep quality among older Chinese adults living in nursing homes.

Methods
This cross-sectional study used multistage cluster random sampling to select 56 nursing homes in Hunan Province, China. Data on sociodemographic characteristics, health-related status, lifestyle, and behavioral and social psychological factors were collected. The Pittsburgh Sleep Quality Index was used to evaluate sleep quality. The 30 mL Water Swallowing Test and Eating Assessment Tool-10 items were used to screen for dysphagia, and the 14th item of the Center for Epidemiologic Studies Depression Scale was used to measure loneliness. Binary logistic regression models were used to analyze the relationship between poor sleep quality, dysphagia, and loneliness. The interaction between these variables was evaluated using multiplicative and additive interaction models.

Results
This study included 3,356 older adults aged 60 and above. The mean Pittsburgh Sleep Quality Index score was 6.31 ± 3.11, and the incidence of poor sleep quality was 30.8%. A total of 642 (19.1%) older adults had dysphagia, and 1,358 (40.5%) experienced loneliness. After adjusting for all covariates, dysphagia and loneliness were associated with an increased risk of poor sleep quality. The interaction analysis demonstrated that the risk of poor sleep quality among older adults with dysphagia and loneliness was 3.476 times higher than that in those without dysphagia and loneliness. Dysphagia and loneliness had an additive interaction effect on poor sleep quality in older adults living in nursing homes.

Conclusions
Poor sleep quality can be effectively prevented by focusing on older adults in nursing homes experiencing dysphagia, loneliness, or both and implementing targeted health interventions.
Deep Learning and Automatic Differentiation of Pancreatic Lesions in Endoscopic Ultrasound: A Transatlantic Study
Authors: Saraiva Miguel Mascarenhas , González-Haba Mariano , Widmer Jessica , Mendes Francisco , Gonda Tamas , Agudo Belen , Ribeiro Tiago , Costa António , Fazel Yousef , Lera Marcos Eduardo , Horneaux de Moura Eduardo , Ferreira de Carvalho Matheus , Bestetti Alexandre , Afonso João , Martins Miguel , Almeida Maria João , Vilas-Boas Filipe , Moutinho-Ribeiro Pedro , Lopes Susana , Fernandes Joana , Ferreira João , Macedo Guilherme 
Published: September 2024

INTRODUCTION:
Endoscopic ultrasound (EUS) allows for characterization and biopsy of pancreatic lesions. Pancreatic cystic neoplasms (PCN) include mucinous (M-PCN) and nonmucinous lesions (NM-PCN). Pancreatic ductal adenocarcinoma (P-DAC) is the commonest pancreatic solid lesion (PSL), followed by pancreatic neuroendocrine tumor (P-NET). Although EUS is preferred for pancreatic lesion evaluation, its diagnostic accuracy is suboptimal. This multicentric study aims to develop a convolutional neural network (CNN) for detecting and distinguishing PCN (namely M-PCN and NM-PCN) and PSL (particularly P-DAC and P-NET).

METHODS:
A CNN was developed with 378 EUS examinations from 4 international reference centers (Centro Hospitalar Universitário São João, Hospital Universitario Puerta de Hierro Majadahonda, New York University Hospitals, Hospital das Clínicas Faculdade de Medicina da Universidade de São Paulo). About 126.000 images were obtained—19.528 M-PCN, 8.175 NM-PCN, 64.286 P-DAC, 29.153 P-NET, and 4.858 normal pancreas images. A trinary CNN differentiated normal pancreas tissue from M-PCN and NM-PCN. A binary CNN distinguished P-DAC from P-NET. The total data set was divided into a training and testing data set (used for model's evaluation) in a 90/10% ratio. The model was evaluated through its sensitivity, specificity, positive and negative predictive values, and accuracy.

RESULTS:
The CNN had 99.1% accuracy for identifying normal pancreatic tissue, 99.0% and 99.8% for M-PCN and NM-PCN, respectively. P-DAC and P-NET were distinguished with 94.0% accuracy.

DISCUSSION:
Our group developed the first worldwide CNN capable of detecting and differentiating the commonest PCN and PSL in EUS images, using examinations from 4 centers in 2 continents, minimizing the impact of the demographic bias. Larger multicentric studies are needed for technology implementation.