bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renin‐angiotensin system blockade promotes a cardio‐renal protection in albuminuric homozygous sickle cell patients
Authors: Haymann Jean‐Philippe , Hammoudi Nadjib , Stankovic Stojanovic Katia , Galacteros Frederic , Habibi Anoosha , Avellino Virginie , Bartolucci Pablo , Benzerara Yahia , Arlet Jean‐Benoit , Djebbar Morad , Letavernier Emmanuel , Grateau Gilles , Tabibzadeh Nathalie , Girshovich Alexei , Chaignon Michel , Girot Robert , Levy Pierre , Lionnet Francois 
Published: October 2017

SummaryThe management of sickle cell nephropathy (SCN) at an early stage is an important issue to prevent renal and cardiovascular morbidity and mortality. This study aimed to evaluate in this population, whether angiotensin converting enzyme inhibitors (ACEIs) treatment could exert a cardio‐renal protection in a SCN cohort. Forty‐two SCN patients (urine albumin:creatinine ratio (ACR) > 10 mg/mmol) were treated with ACEIs for 6 months, then evaluated for ACR, measured glomerular filtration rate (mGFR) together with haematological and cardiovascular parameters. A 1‐month washout was also performed in order to differentiate short‐ and long‐term ACEIs effects. A decrease in ACR baseline value (>30%) was detected in 62% of cases (mean ACR: 46·4 ± 7·6 and 26·4 ± 3·9 mg/mmol at baseline and 6 months respectively; P = 0·002), whereas mGFR values were unchanged. ACR decrease was detected at 1 month following ACEI initiation (32·9 ± 6·9, P = 0·02) with a persistent trend after withdrawal (P = 0·08). ACEIs also decreased diastolic blood pressure (P = 0·007), pulse wave velocity (P = 0·01), tricuspid regurgitation velocity (TRV; P = 0·04), asymmetric dimethyl arginine (ADMA: P = 0·001) and haemoglobin (P = 0·01) while conventional haemolytic biomarkers were unchanged. Our data suggest that ACEIs are safe and effective at decreasing albuminuria in sickle cell patients with a beneficial effect on specific mortality risk factors, such as TRV and asymmetric dimethyl arginine.
In search of a family: The contribution of art psychotherapy to a collaborative approach with a man residing in a forensic learning disability setting
Authors: Caveney Domanic , Wassall Shaun , Rayner Kelly 
Published: October 2017

Accessible Summary

Some clients in learning disability services have problems in their relationships with people.

Some clients with learning disability have broken the law and live in hospital.

For clients in hospital, treatment can be learning about managing behaviour, feelings and relationships. This treatment is given by different professionals.

This treatment is important to help stop these clients getting into trouble with the police again.

An important part of treatment is to help clients understand their experiences in relationships.

This case study is about Oliver, and how psychologists and an art therapist worked together to help him.​

AbstractBackgroundClients with attachment issues are over‐represented in learning disability services. Forensic inpatient services are no exception. Treatment pathways comprise multidisciplinary interventions, and skills‐based treatments are considered vital to recovery and maintenance of prosocial and adaptive behaviour and reduction in risk. An important aspect of treatment is the psychological intervention to enable clients to understand their early experiences and the way this may have impacted on later relationships and behaviour. Without exploring the difficult early lives that many clients in forensic inpatient services have experienced, skills‐based treatments and attempts to facilitate discharge may not be effective.Materials and methodsThis case study presents the theoretical background of attachment, autism, learning disability and sexual offending that informed the collaborative multidisciplinary psychological treatment offered to one man with learning disabilities and autism in a secure forensic setting.ResultsThe introduction of Art Psychotherapy enabled the client to explore his history and the potential internal barriers to his therapeutic progress. Issues of safety and belonging, previously unexplored with this man, were uncovered and these themes were incorporated into his risk formulation and treatment plan.ConclusionsThe paper reflects on the specific contribution of Art Psychotherapy in specialist services, and the importance of the collaborative relationship between the Art Psychotherapist and the ward Multi‐Disciplinary Team.
Active adult lives for persons with learning disabilities—The perspectives of professionals
Authors: Witsø Aud Elisabeth , Kittelsaa Anna M. 
Published: October 2017

Accessible Summary

The government says that all adults should have the opportunity to live active adult lives.

Many people with learning disabilities need support from professionals to realise living active adult lives.

We asked some professionals what active adult living means and they believed it is about self‐determination and making healthy choices.

Some of those we talked to said it was necessary to have more time to support active adult living in people with learning disabilities.

AbstractBackgroundLiving active adult lives is both a value and a right, but the right to do so is associated with restrictions among adults with learning disabilities. This research aimed to capture professionals’ understanding and perception of active adult living for people with learning disabilities living in clustered housing in a Norwegian community.Materials and MethodsField notes and transcripts of interviews were analysed by systematic text condensation based on Giorgi's psychological phenomenological analysis, with focus on the professionals’ own expressions about their experiences and not an exploration of deeper meanings.Results and DiscussionThe analysis identified four main themes: (i) active adult life as independent living and self‐determination, (ii) choice of lifestyle, (iii) accommodation and privacy and (iv) the role of professionals. Results are discussed against concepts like dependence, independence and interdependence.ConclusionThe role of professionals and structural conditions for support and care is crucial for how active adult living is realised for people with learning disabilities. The results highlight the need for further discussions of conditions for active adult living in people with learning disabilities.
Predictive value of BRCA1/2 mRNA expression for response to neoadjuvant chemotherapy in BRCA‐negative breast cancers
Authors: Xu Ye , Ouyang Tao , Li Jinfeng , Wang Tianfeng , Fan Zhaoqing , Fan Tie , Lin Benyao , Xie Yuntao 
Published: October 2017

It is well known that BRCA1 and BRCA2 play a central role in DNA repair, but the relationship between BRCA1 and BRCA2 mRNA expression and response to neoadjuvant chemotherapy in sporadic breast cancer patients has not been well established. Here, we investigate the association between BRCA1 or BRCA2 mRNA expression levels and pathological response in 674 BRCA1/2 mutation‐negative breast cancer patients who received neoadjuvant chemotherapy. BRCA1 and BRCA2 mRNA expression were assessed using quantitative real‐time polymerase chain reaction in core biopsy breast cancer tissue obtained prior to the initiation of neoadjuvant chemotherapy. A total 129 patients (19.1%) achieved pathological complete response (pCR) after neoadjuvant chemotherapy. Among patients treated with anthracycline‐based chemotherapy (n = 531), BRCA1 mRNA low expression patients had a significantly higher pCR rate than intermediate or high BRCA1 mRNA expression groups (24.6% vs 16.8% or 14.0%, P = .031) and retained borderline significance (OR = 1.54, 95% CI = 0.93‐2.56, P = .094) in multivariate analysis. Among the 129 patients who received a taxane‐based regimen, pCR rate showed no differences in BRCA1 low, intermediate, and high mRNA level subgroups (19.6%, 26.8% and 21.4%, respectively; P = .71). BRCA2 mRNA level was not associated with pCR rate in the anthracyline‐based treated subgroup (P = .60) or the taxane‐based regimen subgroup (P = .82). Taken together, our findings suggested that BRCA1 mRNA expression could be used as a predictive marker in BRCA1/2 mutation‐negative breast cancer patients who received neoadjuvant anthracycline‐based treatment.
The Impact of Multilateral Trade Liberalisation on Economic Development: Some Empirical Evidence
Authors: Gnangnon Sena Kimm 
Published: October 2017

AbstractThis article examines the impact of multilateral trade policy liberalisation on countries' levels of economic development, proxied by their real per capita income. The study is particularly relevant in the current context of growing rhetoric against international trade, which could fuel domestic protectionism and would likely undermine multilateral trade liberalisation. The analysis has been conducted on a panel data set of 155 countries, over non‐overlapping four‐yearly sub‐periods during 1995–2014. The empirical results suggest strong support for the view that multilateral trade liberalisation promotes economic development. Hence, the rise in unilateral protectionist trade measures around the world would likely endanger the prospects of further multilateral trade liberalisation and ultimately undermine countries' prospects of economic development.
The Demand for ‘Guard Labour’: Another Explanation
Authors: Geloso Vincent , Kufenko Vadim 
Published: October 2017

AbstractWe consider the argument that inequality drives society to expend more resources on supervision, which imposes an extra cost on doing business – an argument advanced notably by Samuel Bowles, who framed it as a coordination failure. We propose an alternative, though not mutually exclusive, explanation in the form of government failure. We argue that the efforts of government to prohibit drugs leads to increases in violence and policing failure, which in turn force private actors to deploy resources to supervise workers and protect themselves. Our explanation complements and moderates the argument regarding the link between inequality and ‘guard labour’.
Price level convergence and purchasing power divergence
Authors: Eleftheriou Maria , Müller‐Plantenberg Nikolas A. 
Published: October 2017

AbstractWe construct four large data sets of bilateral real exchange rates based on traded good prices (food and clothing, respectively) and broader price indices (consumer price index, CPI, and wholesale price index, WPI). On these data sets, we run non‐parametric regressions to examine how the real exchange rate, the price differential, and the nominal exchange rate react to an overvalued real exchange rate over time. In line with the theory we develop, our regressions show the following: First, real exchange rates are mean‐reverting. Second, prices converge. Third, price convergence implies purchasing power divergence and thus does not contribute to real exchange rate convergence. Indeed, when price adjustment is fast (as for our traded good price data sets), we even observe diverging nominal exchange rates. Our findings suggest that movements both away from and towards PPP may be less related to traded good price movements than is commonly thought.
Optimization of a gadolinium‐rich oxyhalide glass scintillator for gamma ray spectroscopy
Authors: Struebing Christian , Beckert Meredith Brooke , Nadler Jason H. , Kahn Bernd , Wagner Brent , Kang Zhitao 
Published: October 2017

AbstractA transparent gadolinium‐rich oxyhalide glass scintillator was developed for gamma ray spectroscopy with an energy resolution of 14.0% at 662 keV. To the best of our knowledge, this is the highest energy resolution reported for a glass‐based scintillator. The high gadolinium content facilitated a scintillator density of 4.4 g/cm3. The high fluorine and bromine incorporation is advantageous for better uniformity and a good light output of ~3200 Ph/MeV. The peak emission at 431 nm with a FWHM of 90 nm, resulting from the fast Ce3+ transitions, yielded pulse‐height spectra with distinctive peaks from 122 keV to 1.33 keV for gamma radiation from different nuclides.
Chemical stability of KNbO3, NaNbO3, and K0.5Na0.5NbO3 in aqueous medium
Authors: Ozmen Ozcan , Ozsoy‐Keskinbora Cigdem , Suvaci Ender 
Published: October 2017

AbstractIn recent years, potassium sodium niobate (K0.5Na0.5NbO3, KNN) has become popular and promising among perovskite lead‐free piezoceramic systems. In this study, the chemical stability of KNN powders in aqueous medium was investigated as a function of pH, time, and powder surface area. To better understand the dissolution behavior of the complex KNN stoichiometry, subconstituents such as potassium niobate (KNbO3, KN) and sodium niobate (NaNbO3, NN) were investigated separately first. Results showed that all of the cations in the structure underwent dissolution in different values. Indicating that KNN undergoes incongruent dissolution in aqueous medium, the dissolution of A site cations was higher at lower pH while the dissolution of B site cations increased at higher initial pH. The order of released cation concentrations (CA1 = K > CA2 = Na > CB = Nb) fits with inverse relationship of cation field strength (FS) order, B = Nb5+FS > A2 = Na+FS>A1 = K+FS, at pH 4, 7 and 10 for NN, KN, and KNN. Calculated diffuse layer thickness from the ICP data confirmed to outer amorphous layer in TEM image. Also, the ratio of normalized cation concentration versus surface area of powders showed that incongruent dissolution kinetic was driven by the diffusion step.
False gold: Safely navigating open access publishing to avoid predatory publishers and journals
Authors: McCann Terence V. , Polacsek Meg 
Published: October 2017

AbstractAimThe aim of this study was to review and discuss predatory open access publishing in the context of nursing and midwifery and develop a set of guidelines that serve as a framework to help clinicians, educators and researchers avoid predatory publishers.BackgroundOpen access publishing is increasingly common across all academic disciplines. However, this publishing model is vulnerable to exploitation by predatory publishers, posing a threat to nursing and midwifery scholarship and practice. Guidelines are needed to help researchers recognize predatory journals and publishers and understand the negative consequences of publishing in them.DesignDiscussion paper.Data sourcesA literature search of BioMed Central, CINAHL, MEDLINE with Full Text and PubMed for terms related to predatory publishing, published in the period 2007–2017.Implications for NursingLack of awareness of the risks and pressure to publish in international journals, may result in nursing and midwifery researchers publishing their work in dubious open access journals. Caution should be taken prior to writing and submitting a paper, to avoid predatory publishers.FindingsThe advantage of open access publishing is that it provides readers with access to peer‐reviewed research as soon as it is published online. However, predatory publishers use deceptive methods to exploit open access publishing for their own profit. Clear guidelines are needed to help researchers navigate safely open access publishing.ConclusionA deeper understanding of the risks of predatory publishing is needed. Clear guidelines should be followed by nursing and midwifery researchers seeking to publish their work in open access journals.
Structured nurse‐led follow‐up for patients after discharge from the intensive care unit: Prospective quasi‐experimental study
Authors: Jónasdóttir Rannveig J. , Jones Christina , Sigurdsson Gisli H. , Jónsdóttir Helga 
Published: October 2017

AbstractAimsThe aim of this study was to describe a structured 3‐month nurse‐led follow‐up of patients after discharge from intensive care and measure its effects on health status.BackgroundPatients requiring intensive care stay frequently have lengthy and incomplete recovery suggesting need for additional support. The effects of intensive care nurse‐led follow‐up have not been sufficiently elucidated.DesignA prospective, quasi‐experimental study of patients who received structured nurse‐led follow‐up from intensive care nurses after discharge from intensive care until 3 months afterwards. The control group received usual care.MethodsOf 574 patients assessed for eligibility, from November 2012 ‐ May 2015, 168 were assigned to the experimental group (N = 73) and the control group (N = 75). Primary outcome was health status, measured with eight scales of Short Form‐36v2, before the intensive care admission and at four time points until 12 months after intensive care. A mixed effect model tested differences between the groups over time. Criteria for Reporting Development and Evaluation of Complex Interventions 2 guideline, guided the reporting of the intervention.ResultsThe structured nurse‐led follow‐up did not improve patients’ health status compared with usual care (mixed effect model,p = .078–.937).ConclusionThe structured nurse‐led follow‐up did not reveal an effect on the intensive care patients studied. Further examination of intensive care nurse‐led follow‐up is needed, taking into account the heterogeneity of the patient population, variations in length of ward stay, patients’ health care needs during the first week at home after discharge from general ward and health status before intensive care admission.
Incidence and risk factors of colorectal cancer based on 56 324 health checkups: A 7‐year retrospective cohort study
Authors: Fujii Toshiko , Ohisa Masayuki , Sako Toru , Harakawa Takayuki , Sakamune Kazuaki , Nagashima Shintaro , Sugiyama Aya , Matsuura Yuichiro , Tanaka Junko 
Published: October 2017

AbstractBackground and AimAlthough mortality rates of colorectal cancer (CRC) have been increasing in Japan, its screening rates remain stagnant at 19.2% among Japanese population aged > 40 years in 2014. To evaluate the importance of CRC screening by fecal occult blood test (FOBT), this study estimated the incidence of FOBT‐positivity and CRC by sex–age stratification and clarified the risk factors for CRC.MethodsBetween 2007 and 2014, 56 324 residents (21 517 men and 34 807 women) were enrolled in this study. The sex–age‐stratified incidence rates of FOBT‐positivity and CRC were estimated by records from health checkups and colonoscopy. Regarding CRC incidence rate in particular, positive predictive value was adopted to adjust bias of FOBT‐positivity that did not undergo colonoscopy by person‐year method. To investigate the risks of CRC onset, a nested case–control study with 1:10 person‐matching on sex and age was performed.ResultsIncidence rates of FOBT‐positivity and CRC are 4183/100 000 person‐year (100 Kpy) and 141.3/100 Kpy, respectively. In both cases, men has higher incidence rate than women (1.3 times for FOBT; 4977 vs 3718/100 Kpy and 2.3 times for CRC; 217.0 vs 96.4/100 Kpy).ConclusionsThe records from health checkups were useful to estimate incidence rates of CRC with this procedure. The age‐stratified incidence rate indicated the importance of CRC screening by FOBT, especially for men and those aged > 50 years. Additionally, it is strongly recommended to do further investigation if positive for initial FOBT screening especially for those who are > 70 years.
Student veterans’ construction and enactment of resilience: A constructivist grounded theory study
Authors: Reyes A. T. , Kearney C. A. , Isla K. , Bryant R. 
Published: October 2017

Accessible summaryWhat is known on the subject?

Resilience is an ability and a process that allows an individual to develop positive adaptation despite challenges and adversities.

Many military veterans returning to college after their military service have difficulty transitioning to civilian life.

Although some research exists that explores factors related to the resilience of college student veterans, limited theoretical descriptions exist that explain how student veterans construct resilience, and how resilience is enacted and enhanced in their academic and personal (non‐academic) lives.

What this paper adds to existing knowledge?

The resilience of student veterans involves a complex process of transitioning from military to civilian life and an iterative journey between positive adaptation and transient perturbations.

Student veterans’ resilience is a result of integrating and resolving various aspects of their academic and personal challenges.

What are the implications for practice?

Nurses can apply this grounded theory as a practical framework for equipping student veterans with effective strategies to develop and enhance resilience.

Nurses can employ a holistic approach of care in their interactions with military veterans and student veterans that includes fostering psychological resilience, helping to manage their multiple non‐academic responsibilities and supporting their academic success.

AbstractIntroductionAdjusting to college life is one of the most difficult experiences in a military veteran's transition to civilian life. Many military veterans returning to college not only encounter academic challenges, but also deal with physical and psychiatric disabilities, loss of military camaraderie and social disconnect. These often negatively affect their personal and academic lives. Hence, it is important to explore resilience to best support student veterans as they transition from military to civilian life.AimThe aim of this study was to explore how student veterans construct and enact resilience within their personal and academic lives.MethodUsing constructivist grounded theory methodology, in‐depth individual interviews were conducted with 20 military veterans enrolled as undergraduate students at a U.S. university.ResultsThe process of “integrating,” which represents student veterans’ construction and enactment of resilience, was the core category. This category has three subcategories: (1) the aspects; (2) the expressions; and (3) the enactments of resilience.Implications for practiceNurses can use this grounded theory as the practical framework for their interactions with military veterans, and more particularly with supporting student veterans in their academic lives, in their personal lives and in the transition from military to civilian life.
Validation of the German version of the Ford Insomnia Response to Stress Test
Authors: Dieck Arne , Helbig Susanne , Drake Christopher L. , Backhaus Jutta 
Published: October 2017

SummaryThe purpose of this study was to assess the psychometric properties of a German version of the Ford Insomnia Response to Stress Test with groups with and without sleep problems. Three studies were analysed. Data set 1 was based on an initial screening for a sleep training program (n = 393), data set 2 was based on a study to test the test–retest reliability of the Ford Insomnia Response to Stress Test (n = 284) and data set 3 was based on a study to examine the influence of competitive sport on sleep (n = 37). Data sets 1 and 2 were used to test internal consistency, factor structure, convergent validity, discriminant validity and test–retest reliability of the Ford Insomnia Response to Stress Test. Content validity was tested using data set 3. Cronbach's alpha of the Ford Insomnia Response to Stress Test was good (α = 0.80) and test–retest reliability was satisfactory (r = 0.72). Overall, the one‐factor model showed the best fit. Furthermore, significant positive correlations between the Ford Insomnia Response to Stress Test and impaired sleep quality, depression and stress reactivity were in line with the expectations regarding the convergent validity. Subjects with sleep problems had significantly higher scores in the Ford Insomnia Response to Stress Test than subjects without sleep problems (P < 0.01). Competitive athletes with higher scores in the Ford Insomnia Response to Stress Test had significantly lower sleep quality (P = 0.01), demonstrating that vulnerability for stress‐induced sleep disturbances accompanies poorer sleep quality in stressful episodes. The findings show that the German version of the Ford Insomnia Response to Stress Test is a reliable and valid questionnaire to assess the vulnerability to stress‐induced sleep disturbances.