bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of the Electronic Medical Record to Facilitate Intervention for Patients With Rising Prostate-Specific Antigen Values After Radical Prostatectomy: A Feasibility Study
Authors: Kishan Amar U. , Cheng Eric M. , Schmidt Eric , Saigal Christopher , Reiter Robert E. , Kupelian Patrick A. , Steinberg Michael L. , King Christopher R. 
Published: July 2017

Purpose Salvage radiotherapy (SRT) is the standard of care offered when postprostatectomy prostate-specific antigen (PSA) levels are ≥ 0.2 ng/mL. However, emerging evidence suggests that early SRT (ie, SRT delivered at PSA values < 0.2 ng/mL, but generally ≥ 0.05 ng/mL) improves oncologic outcomes. We evaluated the feasibility of improving referral rates for discussion of early SRT by using a dynamic registry that identifies through the electronic medical record patients with rising postprostatectomy PSA levels. Methods We developed an iteratively updated registry that identifies patients who fall within two postoperative PSA strata: ≥ 0.05 to < 0.1 ng/mL and ≥ 0.1 to < 0.2 ng/mL. We compared referral rates to radiation oncology during a 3-year period before use of this registry with those during a 1-year period after promotion of the registry in multidisciplinary tumor board settings. Results Before promotion of the registry, referral rates for patients with PSA values ≥ 0.05 to < 0.1 ng/mL and ≥ 0.1 to < 0.2 ng/mL were 35% and 65%, respectively. After promotion of the registry, referral rates within each stratum increased significantly to 82% and 94%, respectively ( P < .05 for both by Fisher’s exact test). The overall rate of referral for patients with PSA values ≥ 0.05 to < 0.2 ng/mL rose from 48% to 90% ( P < .001). Conclusion The creation of a registry of patients with rising postprostatectomy PSA values can facilitate increased referral rates for early SRT without burdening providers with a clinical support tool embedded within the EMR itself. This is true even in the case of already high baseline rates of referral for early SRT. The changes reported herein most likely reflect a Hawthorne effect wherein the ability to track referrals rather than a direct function of the registry influenced practice patterns. Nonetheless, the registry provided an integral framework to allow for tracking.
Uncommon neoplasms of the biliary tract: radiological findings
Authors: Granata Vincenza , Fusco Roberta , Catalano Orlando , Filice Salvatore , Avallone Antonio , Piccirillo Mauro , Leongito Maddalena , Palaia Raffaele , Grassi Roberto , Izzo Francesco , Petrillo Antonella 
Published: July 2017

Objective:
To report our cancer centre experience in the biliary tumours incidence other than cholangiocellular-carcinoma, emphasizing the radiological features.

Methods:
197 patients with biliary disease undergoing Gd-EOB-DTPA-enhanced MRI were reviewed. Four radiologists evaluated retrospectively size, structure, anatomical site and signal intensity of lesions on MRI. Enhancement-pattern during the arterial-, portal- and late-phase on ultrasound, CT and MR study was assessed as well as the enhancement pattern during the hepatobiliary-phase on MRI.

Results:
23 patients were selected. The lesion was intraductal in 5 cases, periductal in 14 and intrahepatic in 4. 16 lesions were solid, 5 uniloculated cystic and 2 complex cystic. In five patients the lesion was simple cyst, with a signal intensity in T 1 weighted (T1W) and T 2 weighted (T2W) similar to the gallbladder. In two patients with complex cystic lesion, the solid component was heterogeneously hypointense in T 1 W, hyperintense in T 2 W with a restricted diffusion. The solid component showed heterogeneous contrast-enhancement on CT, MR and ultrasound. The tumour was intrahepatic in two patients, with signal hypointense in T 1 W and hyperintense in T 2 W. Diffusion was restricted. The lesions showed heterogeneous contrast-enhancement. The periductal lesions were hypointense in T 1 W, hyperintense in T 2 W with restricted diffusion. The lesion showed progressive contrast-enhancement. Peribiliary melanoma was hyperintense in T 1 W, hyperintense in T 2 W with restricted diffusion and progressively contrast-enhanced.

Conclusion:
Biliary tumours can have a wide spectrum of radiologic appearances and consequently represent a diagnostic challenge for the radiologist.

Advances in knowledge:
MRI is the technique of choice in diagnosing biliary tumours, including rare (non-CCC) tumours.
Η Κρίση και τα Μνημόνια Ισοπεδώνουν την Εργασία
Authors: Κουζής Γιάννης 
Published: July 2017

Οι αλλαγές που συντελούνται στο πεδίο της εργασίας κατά την περίοδο της κρίσης και των μνημονίων στην Ελλάδα χαρακτηρίζονται από μια βίαιη ανατροπή των εργασιακών σχέσεων στην κατεύθυνση της εργασιακής απορρύθμισης που καταγράφεται σταδιακά, αλλά με βραδύτερους ρυθμούς, από τις αρχές της δεκαετίας του 1990 στη χώρα. Η περίοδος των μνημονίων που συνοδεύουν την κρίση αποτελεί την αφορμή για την ραγδαία εντατικοποίηση των ρυθμών απελευθέρωσης της «αγοράς εργασίας» σε βαθμό που, σε τόσο σύντομο χρονικό διάστημα, συμβάλλει στην διαμόρφωση ενός εντελώς νέου εργασιακού τοπίου. Οι εξελίξεις αυτές, σε συνάρτηση με τα πρωτοφανή μεταπολεμικά ποσοστά ανεργίας, επηρεάζουν καθοριστικά το περιεχόμενο των εργασιακών σχέσεων και συνεπάγονται σοβαρές παρενέργειες στο πεδίο των συνθηκών εργασίας και διαβίωσης σε συνδυασμό με την συντελούμενη απορρύθμιση του ανέκαθεν ελλειμματικού κράτους πρόνοιας στην Ελλάδα. Η πλήρης αποδιάρθρωση του συστήματος των συλλογικών συμβάσεων και του τρόπου διαμόρφωσης των μισθών, η απελευθέρωση των ατομικών και ομαδικών απολύσεων, η ελαστικοποίηση των ωραρίων και η ενίσχυση των ευέλικτων μορφών εργασίας σε βάρος της πλήρους και σταθερής απασχόλησης αποτελούν τους κύριους άξονες στους οποίους κινούνται οι εν λόγω αλλαγές. Αυτές συμπληρώνονται και από δραστικά μέτρα περιορισμού της απασχόλησης και υποβάθμισης της εργασίας στον δημόσιο τομέα στο πλαίσιο της συντελούμενης σύγκλισης του εργασιακού καθεστώτος του Δημοσίου με το αντίστοιχο που ισχύει στις ιδιωτικές επιχειρήσεις με όρους συνολικής υποβάθμισης και απορρύθμισης της εργασίας. Οι επιβαλλόμενες αλλαγές στην Ελλάδα από ισχυρούς εθνικούς και διεθνείς οικονομικούς κύκλους δημιουργούν μια περιοχή χαμηλών δαπανών για την εργασία κατάλληλη για υψηλή κερδοφορία του κεφαλαίου εντός του χώρου της ευρωζώνης. Παράλληλα αποτελούν το έναυσμα για την επέκταση του ελληνικού πειράματος στον υπόλοιπο ευρωπαϊκό νότο σε ένα γενικότερο πλαίσιο εργασιακής απορρύθμισης που καταγράφεται στην γηραιά ήπειρο, στο σύνολό της, κατά τις τελευταίες δεκαετίες και την υιοθέτηση από την Ευρωπαϊκή Ένωση παρεμβάσεων στην αγορά εργασίας με στόχο την ανταγωνιστικότητα των επιχειρήσεων και με άξονα την ευελιξία της εργασίας για την επίτευξη χαμηλότερου «εργατικού κόστους».
Proteolytic processing of the L-type Ca2+ channel alpha11.2 subunit in neurons
Authors: Buonarati Olivia R. , Henderson Peter B. , Murphy Geoffrey G. , Horne Mary C. , Hell Johannes W. 
Published: July 2017

Background: The L-type Ca2+ channel Cav1.2 is a prominent regulator of neuronal excitability, synaptic plasticity, and gene expression. The central element of Cav1.2 is the pore-forming α11.2 subunit. It exists in two major size forms, whose molecular masses have proven difficult to precisely determine. Recent work suggests that α11.2 is proteolytically cleaved between the second and third of its four pore-forming domains (Michailidiset al,. 2014).Methods: To better determine the apparent molecular masses (MR)of the α11.2 size forms, extensive systematic immunoblotting of brain tissue as well as full length and C-terminally truncated α11.2 expressed in HEK293 cells was conducted using six different region–specific antibodies against α11.2.Results: The full length form of α11.2 migrated, as expected, with an apparent MRof ~250 kDa. A shorter form of comparable prevalence with an apparent MRof ~210 kDa could only be detected in immunoblots probed with antibodies recognizing α11.2 at an epitope 400 or more residues upstream of the C-terminus.Conclusions: The main two size forms of α11.2 are the full length form and a shorter form, which lacks ~350 distal C-terminal residues. Midchannel cleavage as suggested by Michailidiset al. (2014) is at best minimal in brain tissue.
Robust Adaptive Routing Under Uncertainty
Authors: Flajolet Arthur , Blandin Sébastien , Jaillet Patrick 
Published: July 2017

We consider the problem of finding an optimal history-dependent routing strategy on a directed graph weighted by stochastic arc costs when the objective is to minimize the risk of spending more than a prescribed budget. To help mitigate the impact of the lack of information on the arc cost probability distributions, we introduce a robust counterpart where the distributions are only known through confidence intervals on some statistics such as the mean, the mean absolute deviation, and any quantile. Leveraging recent results in distributionally robust optimization, we develop a general-purpose algorithm to compute an approximate optimal strategy. To illustrate the benefits of the robust approach, we run numerical experiments with field data from the Singapore road network. The e-companion is available at https://doi.org/10.1287/opre.2017.1662 .
Characteristics of women with unplanned pregnancy: results from Botswana AIDS Impact Survey IV
Authors: Mogobe Keitshokile Dintle , Tshiamo Wananani 
Published: July 2017

Background: In sub-Saharan Africa, there are 40 million pregnancies each year. Of these, one-quarter are unplanned and have negative health and socio-economic consequences. Aim: The aim of this article is to share findings on demographic characteristics of childbearing women who reported unplanned pregnancy. Methods: Botswana AIDS Impact Survey IV data were used to respond to the question, ‘What are the demographic characteristics of women who reported unplanned pregnancy in Botswana?’ The data extracted related to 311 687 women who responded to the question, ‘Have you given birth in the past 5 years?’ The authors then focused on data for 160 482 women who responded to the question ‘Was the last pregnancy planned?’ Using SPSS version 22, frequencies, means and standard deviations were calculated and demographic characteristics were analysed. Findings: More women with low educational status, unemployed, never married or cohabiting and residing in rural areas reported unplanned pregnancy. Conclusions: Unplanned pregnancy in Botswana requires targeted interventions.
Fetal heart rate monitoring: the challenge in under-resourced settings
Authors: Jagau Anneke , Maughan-Brown Rebecca , Fawcus Sue R , Crede Sarah , Woods David , Lawn Joy E 
Published: July 2017

Background: Intrapartum-related deaths are the second most common cause of neonatal death, resulting in 1.2 million stillbirths each year, many of which could be prevented with improved intrapartum monitoring. The partograph was developed as a tool to help health professionals to provide better and more efficient care during labour. This study set out to address whether this low-cost tool was reaching under-resourced settings and whether it was being used correctly. Aim: To assess barriers and enablers for the use of a partograph in under-resourced settings, especially to monitor fetal heart rate. Method: Evaluation of 538 partographs as well as in-depth interviews and knowledge assessments with 24 midwives. Findings: The general score for partograph use and completion was 59.3%. The score for fetal heart rate assessment was 56%. The midwives interviewed felt that partograph use and fetal heart rate monitoring were important but also felt insecure and undertrained in this aspect of midwifery practice. Conclusions: This review showed that very few partographs were completed according to standard, despite the fact that the midwives knew the importance of fetal heart rate monitoring and were motivated to monitor well. Time constraints and a lack of training were identified as the biggest barriers to correct monitoring.
Concepts of the database in contemporary media practice
Authors: Moran Ruth Alexandra 
Published: July 2017

Abstract
Contemporary remix practices in online video have flourished, due to the unprecedented access to our shared media culture that has been made possible by the databases underpinning online space. The technological and functional specificities of the database intercede our experiences in digital culture and influence how we understand our culture that increasingly occupies the database. They also influence how we express ideas about that culture through creative practices. The technological and, correspondingly, cultural significances of the database are articulated in the digitally specific remix video sub-genre, YouTube Poop. YouTube Poop relies on the database for the existing media content that it appropriates. Moreover, it narratively and aesthetically responds to the database by articulating the concepts of technological error, ahistoricism, multi-temporality, media abundance, the constant availability and the achronological, non-hierarchical, unclassified nature of media that the database has introduced to contemporary culture. In this article, the audio-visual narratives of three recent YouTube Poop videos are analysed in order to establish how they articulate the conceptual implications of the database in contemporary digital culture.
Da-Sein design: Linking phenomenology with Self-Determination Theory for game design
Authors: Conway Steven , Elphinstone Bradley 
Published: July 2017

Abstract
In this article we propose a phenomenological foundation for the application of Self-Determination Theory (SDT) in game design. While SDT provides much value in describing why a person engages with and is motivated to continue engaging with games (of all types) as meaningful experiences, it currently lacks an overt definition of meaning and how it occurs. We argue that the Heideggerian phenomenology offers an explicit delineation of meaning in the human experience, and, furthermore, is already implicit in the conceptualization of SDT’s core needs, as we demonstrate. Finally, we show how this understanding of meaning (phenomenology) and needs (SDT) can be fruitfully linked to provide a robust set of theoretical concepts for comprehending the experience of gameplay through a short case study of the camera system as designed within digital games.
What you hear is what you (don’t) see. Mario Wienerroither’s Foley art in Musicless Musicvideos
Authors: Dotto Simone 
Published: July 2017

Abstract
Mario Wienerrother’s Musicless Musicvideos series have recently surfaced on the Internet and since 2006, they have gained millions of views as a humorous YouTube sensation. As a professional sound designer, he re-edits already released and often widely known music videos by depriving them of music and adding a different, entirely sonic audio track that he records himself. All of these reworkings seem to raise the same hypothetical question: what if these audio-visual excerpts were deprived of their most signifying aural expression, namely music? Would they still have the same meaning? Would they tell the same ‘story’? This article aims to explore Wienerroither’s practices and the effects they provoke on our understanding of the aesthetic conventions of the music video. As a first step, I will provide a detailed account of the process for realizing the Musicless Musicvideos by drawing on an interview I carried out with the author. Secondly, I will investigate a number of Wienerroither’s productions in relation to (1) the aesthetic conventions of music video and (2) the practical realm of Foley artistry. Through these comparisons, I will explore how the renewed sonic dimension in these videos matches the settings, objects and human figures we see on-screen and the extent to which this can change our understanding of the images themselves, through the production of a humorous effect and the construction of a sonic diegesis superimposed to the re-edited materials. The objective of the article is to demonstrate how, by relying on a sound-centred practice, Musicless Musicvideos undermine the overall balance between the visual and the aural elements in a typical music video.
‘Formation’ of the female author in the hip hop visual album: Beyoncé and FKA twigs
Authors: Barrett Ciara 
Published: July 2017

Abstract
This article explores how and why, from a feminist standpoint, two black female hip hop artists – Beyoncé and FKA twigs – have turned in recent years to the emerging audio-visual format of the visual album towards a radical expression of female authorship. This is ‘radical’, specifically, in two contexts: firstly hip hop, the genre with which these artists are traditionally associated and which has been associated, historically, with a repressive politics of gender and race representation through music videos and secondly, that of the classical paradigm of film style and narration, which the visual album as long-form video implicitly confronts. Synthesizing traditional feminist film theory with more recent theorization of music video aesthetics and representational trends, this article considers how Beyoncé and FKA twigs have remediated certain formal and narrative paradigms of film and music video to create a uniquely hybrid form. Beyoncé’s self-titled visual album from 2013 will be considered as an initial interrogation-cum-problematization of the sexist representational paradigms endemic to hip hop music videos and classical cinema from the inside out, while her more recent Lemonade and twigs’s M3ll155X will be analysed as radically formally innovative and assertive of a subjective, female authorial voice. These two artists will be seen to have self-consciously invoked a filmic mode of representation and spectatorship across the formally experimental audio-visual format of the video album to exert a remarkable degree of control over their audio-self-images’ narrativization and signification.
High-octave soprano to auto-tuned rapper: Item numbers and technologies of sonic eroticism
Authors: Mukherjee Silpa 
Published: July 2017

Abstract
The item number, a microfilmic musical form, has been shaped by a wide range of intersecting influences: the fashion industry, music video culture and the 24/7 music television format introduced with globalization in India. The name item number (a special song and dance sequence) is probably derived from the term ‘item’ (nowadays used for petite gay men as well), the Bombaiya equivalent of the slang ‘looker’, the worst way of objectifying a human body by disintegrating it into individual units (items). Item numbers tend to be big budget productions, like stand-alone attractions that are staged to have a life independent of the narrative. The production economy for these dances is intricately designed with a special focus on sets, costumes, make-up, digital technologies for lighting, music, cinematography and editing. The identifying marker of an item number is the way in which it foregrounds the body as a sexualized force. In this article, I locate the sensual affect of the item number in its sonic template. DJs, rappers, playback sopranos and mixing engineers are the assembling figures of this article. While questions of new media technologies, in terms of lip-syncing and digital mixing battles, form the vortex of enquiry here, cultural references to the gender and sexual charge of the voices are equally significant. I argue that the technical matrices of its circulation, sound amplification and the performative force of the item number conjure a new sonic ecology that heightens the wildness that is associated with its loud sound. The article also enquires into censorship debates that frame this sonic eroticism.
Finding meaning in data: Using data elements to sonify and visualize the found environment
Authors: Tsang Cissi 
Published: July 2017

Abstract
Visiting a natural setting can be a deeply visceral experience. Experiencing a landscape is a two-part process: firstly, the senses take in information from a three-dimensional world – for most of us, these take the forms of sights and sounds. Secondly, this information is translated into a mental landscape flecked with the nuances of personal meaning. How one interprets a landscape cannot be separated from the observer; our personal experiences (and biases) filter and colour our observations. Arguably, the use of landscapes in the creation of artefacts is a form of communicative expression, both between the artist and the landscape and between the artist and their own experiences. These considerations then raise the question of how an artist can then depict these visual and aural experiences, and the impact they have on the artist, as tangible artefacts that can be shared with others? One answer is through the creation of audio-visual works that combine the visual and aural aspects of a setting, and which then leads to another question: how do you create – or re-create – representations of a landscape? How does one establish relationships and associations between visual and aural information drawn from the found environment (i.e. the environment in situ as seen and heard through the eyes and ears of an observer) and place these into audio-visual compositions? This article explores the creation of audio-visual representations of the found environment using elements of data as methods of sonification, the compositional processes involved with organizing these data elements, using data as a structural process that informs the parameters of a composition and the use of music visualization. Multiple data elements such as hexadecimal data, field footage, field recordings and contours of a landscape can be used to sonify the found environment by creating multiple perspectives of the environment into the work. It also strengthens the connection between the aural and the visual by creating links between both mediums. This article will discuss these points through analysis of the creation of Civil Eyes // The Wild, an audio-visual performance that was commissioned by the You Are Here Festival in 2016 – using the performance as an example of how the found environment can be used as parameters for sonification and visualization.