bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relation between the Co-O bond lengths and the spin state of Co in layered Cobaltates: a high-pressure study
Authors: Chin Yi-Ying , Lin Hong-Ji , Hu Zhiwei , Kuo Chang-Yang , Mikhailova Daria , Lee Jenn-Min , Haw Shu-Chih , Chen Shin-An , Schnelle Walter , Ishii Hirofumi , Hiraoka Nozomu , Liao Yen-Fa , Tsuei Ku-Ding , Tanaka Arata , Hao Tjeng Liu , Chen Chien-Te , Chen Jin-Ming 
Published: June 2017

AbstractThe pressure-response of the Co-O bond lengths and the spin state of Co ions in a hybrid 3d-5d solid-state oxide Sr2Co0.5Ir0.5O4 with a layered K2NiF4-type structure was studied by using hard X-ray absorption and emission spectroscopies. The Co-K and the Ir-L
3
X-ray absorption spectra demonstrate that the Ir5+ and the Co3+ valence states at ambient conditions are not affected by pressure. The Co Kβ emission spectra, on the other hand, revealed a gradual spin state transition of Co3+ ions from a high-spin (S = 2) state at ambient pressure to a complete low-spin state (S = 0) at 40 GPa without crossing the intermediate spin state (S = 1). This can be well understood from our calculated phase diagram in which we consider the energies of the low spin, intermediate spin and high spin states of Co3+ ions as a function of the anisotropic distortion of the octahedral local coordination in the layered oxide. We infer that a short in-plane Co-O bond length (<1.90 Å) as well as a very large ratio of Co-Oapex/Co-Oin-plane is needed to stabilize the IS Co3+, a situation which is rarely met in reality.
C-C Chemokine Ligand-5 is critical for facilitating macrophage infiltration in the early phase of liver ischemia/reperfusion injury
Authors: Lee Chiou-Mei , Peng Hsin-Hsin , Yang Polung , Liou Jiin-Tarng , Liao Chia-Chih , Day Yuan-Ji 
Published: June 2017

AbstractCCL5/RANTES, a chemoattractant for myeloid cells, is induced by hepatic ischemia/reperfusion injury (IRI). The roles of CCL5 in hepatic IRI were carried out by means of CCL5 immunodepletion, antagonistic competition by Met-CCL5, and treatment with recombinant murine CCL5 (rmCCL5). Depletion or inhibition of CCL5 reduced severity of hepatic IRI, whereas rmCCL5 treatment aggravated liver IRI as manifested in elevated serum alanine aminotransferase (ALT) and tissue myeloperoxidase (MPO) levels. Moreover, IRI severity was reduced in CCL5-knockout (CCL5-KO) mice versus wildtype (WT) mice, with drops in serum ALT level, intrahepatic MPO activity, and histological pathology. Bone marrow transplantion (BMT) studies show that myeloid cells and tissue cells are both required for CCL5-aggravated hepatic IRI. The profile of liver-infiltrating leukocyte subsets after hepatic reperfusion identified CD11b+ cells as the only compartment significantly reduced in CCL5-KO mice versus WT controls at early reperfusion phase. The role of CCL5 recruiting CD11b+ cells in early reperfusion was validated by in vitro transwell migration assay of murine primary macrophages (broadly characterized by their CD11b expression) in response to liver lysates after early reperfusion. Taken together, our results demonstrate a sequence of early events elicited by CCL5 chemoattracting macrophage that result in inflammatory aggravation of hepatic IRI.
Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells
Authors: Piltti Juha , Bygdell Joakim , Fernández-Echevarría Cecilia , Marcellino Daniel , Lammi Mikko J. 
Published: June 2017

AbstractArticular chondrocytes are slowly dividing cells that tend to lose their cell type-specific phenotype and ability to produce structurally and functionally correct cartilage tissue when cultured. Thus, culture conditions, which enhance the maintenance of chondrocyte phenotype would be very useful for cartilage research. Here we show that Rho-kinase inhibition by Y-27632 under hypoxic conditions efficiently maintains and even enhances chondrocyte-specific extracellular matrix production by chondrocytic cells. The effects of long-term Y-27632 exposure to human chondrosarcoma 2/8 cell phenotype maintenance and extracellular matrix production were studied at normoxia and at a 5% low oxygen atmosphere. Y-27632 treatment at normoxia induced ACAN and COL2A1 gene up-regulation and a minor increase of sulfated glycosaminoglycans (sGAGs), while type II collagen expression was not significantly up-regulated. A further increase in expression of ACAN and COL2A1 was achieved with Y-27632 treatment and hypoxia. The production of sGAGs increased by 65.8%, and ELISA analysis revealed a 6-fold up-regulation of type II collagen. Y-27632 also induced the up-regulation of S100-A1 and S100-B proteins and modified the expression of several other S100 protein family members, such as S100-A4, S100-A6, S100-A13 and S100-A16. The up-regulation of S100-A1 and S100-B proteins is suggested to enhance the chondrocytic phenotype of these cells.
Human bipedalism and body-mass index
Authors: Yi Su Do , Noh Jae Dong , Minnhagen Petter , Song Mi-Young , Chon Tae-Soo , Kim Beom Jun 
Published: June 2017

AbstractBody-mass index, abbreviated as BMI and given by M/H2 with the mass M and the height H, has been widely used as a useful proxy to measure a general health status of a human individual. We generalise BMI in the form of M/H
p
and pursue to answer the question of the value of p for populations of animal species including human. We compare values of p for several different datasets for human populations with the ones obtained for other animal populations of fish, whales, and land mammals. All animal populations but humans analyzed in our work are shown to have p ≈ 3 unanimously. In contrast, human populations are different: As young infants grow to become toddlers and keep growing, the sudden change of p is observed at about one year after birth. Infants younger than one year old exhibit significantly larger value of p than two, while children between one and five years old show p ≈ 2, sharply different from other animal species. The observation implies the importance of the upright posture of human individuals. We also propose a simple mechanical model for a human body and suggest that standing and walking upright should put a clear division between bipedal human (p ≈ 2) and other animals (p ≈ 3).
Effect of sliding friction in harmonic oscillators
Authors: Vitorino Miguel V , Vieira Arthur , Rodrigues Mario S 
Published: June 2017

AbstractSliding friction is ubiquitous in nature as are harmonic oscillators. However, when treating harmonic oscillators the effect of sliding friction is often neglected. Here, we propose a simple analytical model to include both viscous and sliding friction in common harmonic oscillator equations, allowing to separate these different types of dissipation. To compare this model with experimental data, a nanometric vibration was imposed on a quartz tuning fork, while an atomic force microscope tip was used to disturb its motion. We analyzed tuning fork resonance and ‘ring down’ experimental curves and for each case calculated the amount of sliding friction and of viscous damping, finding an agreement between the two different experiments and the model proposed.
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer
Authors: Xie Ruyi , Wang Jing , Liu Xuehua , Wu Liqing , Zhang Hui , Tang Weimei , Li Yueqiao , Xiang Li , Peng Ying , Huang Xiaoting , Bai Yang , Liu Guangnan , Li Aimin , Wang Yadong , Chen Ye , Ren Yuexin , Li Guoxin , Gong Wei , Liu Side , Wang Jide 
Published: June 2017

AbstractRUFY3 is highly expressed in brain tissue and has a role in neuronal development. Transcriptional factor FOXK1 is involved in cell growth and metabolism. We knew that RUFY3 or FOXK1 has been correlated with the malignant of tumor cells. However, the role of these molecules in colorectal cancer (CRC) progression remains unknown. We investigated the protein expression levels by Western blot, immunofluorescence and immunohistochemistry analyses. The migration and invasive abilities of CRC cells were assessed using shRNA-mediated inhibition in vitro and in vivo. We showed that RUFY3 expression was up-regulated in CRC compared with its expression in a normal human colon cell line (FHC). RUFY3 suppression inhibited anchorage independent cell tumorigenesis. RUFY3 induced elevated expression of eight major oncogenes. Moreover, RUFY3 physically interacts with FOXK1 in CRC. A positive correlation was observed between the expression patterns of RUFY3 and FOXK1. Furthermore, RUFY3 and FOXK1 expression were correlated with tumor progression and represented significant predictors of overall survival in CRC patients. SiRNA-mediated repression of FOXK1 in RUFY3-overexpressing cells reversed the epithelial-mesenchymal transition (EMT) and metastatic phenotypes. In vivo, FOXK1 promoted RUFY3-mediated metastasis via orthotopic implantation. These findings suggest that the RUFY3-FOXK1 axis might promote the development and progression of human CRC.
Asymptotic g modes: Evidence for a rapid rotation of the solar core
Authors: Fossat E. , Boumier P. , Corbard T. , Provost J. , Salabert D. , Schmider F. X. , Gabriel A. H. , Grec G. , Renaud C. , Robillot J. M. , Roca-Cortés T. , Turck-Chièze S. , Ulrich R. K. , Lazrek M. 
Published: June 2017

Context. Over the past 40 years, helioseismology has been enormously successful in the study of the solar interior. A shortcoming has been the lack of a convincing detection of the solar g modes, which are oscillations driven by gravity and are hidden in the deepest part of the solar body – its hydrogen-burning core. The detection of g modes is expected to dramatically improve our ability to model this core, the rotational characteristics of which have, until now, remained unknown.
Aims. We present the identification of very low frequency g modes in the asymptotic regime and two important parameters that have long been waited for: the core rotation rate, and the asymptotic equidistant period spacing of these g modes.
Methods. The GOLF instrument on board the SOHO space observatory has provided two decades of full-disk helioseismic data. The search for g modes in GOLF measurements has been extremely difficult because of solar and instrumental noise. In the present study, the p modes of the GOLF signal are analyzed differently: we search for possible collective frequency modulations that are produced by periodic changes in the deep solar structure. Such modulations provide access to only very low frequency g modes, thus allowing statistical methods to take advantage of their asymptotic properties.
Results. For oscillatory periods in the range between 9 and nearly 48 h, almost 100 g modes of spherical harmonic degree 1 and more than 100 g modes of degree 2 are predicted. They are not observed individually, but when combined, they unambiguously provide their asymptotic period equidistance and rotational splittings, in excellent agreement with the requirements of the asymptotic approximations. When the period equidistance has been measured, all of the individual frequencies of each mode can be determined. Previously, p-mode helioseismology allowed the g-mode period equidistance parameter P0 to be bracketed inside a narrow range, between approximately 34 and 35 min. Here, P0 is measured to be 34 min 01 s, with a 1 s uncertainty. The previously unknown g-mode splittings have now been measured from a non-synodic reference with very high accuracy, and they imply a mean weighted rotation of 1277 ± 10 nHz (9-day period) of their kernels, resulting in a rapid rotation frequency of 1644 ± 23 nHz (period of one week) of the solar core itself, which is a factor 3.8 ± 0.1 faster than the rotation of the radiative envelope.
Conclusions. The g modes are known to be the keys to a better understanding of the structure and dynamics of the solar core. Their detection with these precise parameters will certainly stimulate a new era of research in this field.
What Is High Enough? Elevated NT-pro-BNP in Decompensated Paroxysmal Supraventricular Tachycardia
Authors: Womack Clayton , Lutherer L. , Todd Christopher , Pinkney Kerrie , Kasemsri Thivakorn , Reeves Shawn 
Published: June 2017

AbstractSince the late 1980s, elevated atrial natriuretic peptide (ANP) was considered the cause of brisk diuresis in adult patients with paroxysmal supraventricular tachycardia (PSVT). Pro-brain natriuretic peptide (pro-BNP) and related molecules, e.g., N-terminal pro b-type natriuretic peptide (NT-pro-BNP) are known biomarkers of heart failure in adult patients from many causes with probable relevance in children. Perhaps, pro-BNP or related molecules such as NT-pro-BNP are useful in the management of PSVT in infants, thus hastening treatment in children who may otherwise significantly decompensate. Case series of one infant and two neonates presenting with cardiogenic shock and evidence of heart failure are presented. Cardiac monitoring or electrocardiogram (ECG) confirmed the presence of PSVT. Adenosine was administered resulting in successful chemical cardioversion with each case. Significantly elevated NT-pro-BNP levels correlated with heart failure prior to cardioversion. In each case, patients were discharged home with lower NT-pro-BNP levels and maintenance with a β-blocker. Due to documented relationships between elevated pro-BNP level and heart failure in adults, the authors measured the related biomarker NT-pro-BNP in each case, as the relationship could be similar in pediatric PSVT. Based on our experience with children in acute heart failure from other causes, NT-pro-BNP can increase to potentially extreme levels in infants. It appears to correlate with clinical signs of insufficient cardiac output, such as tachycardia, respiratory distress, and moribund appearance. Indeed, in the case series, extremely high NT-pro-BNP values were obtained when the patients appeared moribund from decompensated PSVT. The question arising from these observations is: At what level of elevated NT-pro-BNP, would patients be identified for cardioversion prior to appearance of other signs and symptoms? For each patient within the case series, NT-pro-BNP levels of approximately 20,000 pg/mL were indicative of decompensated heart failure, which was subsequently confirmed by examination of the patient. Further investigation is needed to determine the clinical significance of NT-pro-BNP and related peptides in pediatric patients with PSVT and intermittent PSVT. However, the possibility exists that an increase in NT-pro-BNP and related peptides could be a biomarker for cardiac decompensation after prolonged or intermittent PSVT, thereby shortening the time of diagnosis and intervention, and hence, potentially preventing morbidity, mortality, and extended hospitalization. Additional evidence-based research would help provide biomarker information during PSVT allowing practitioners to more objectively analyze risks.
Revisiting Retrograde Ventriculosinus Shunt as an Alternative for Treating Hydrocephalus in Children
Authors: Oliveira Matheus , Teixeira Manoel , Oliveira Marcelo , Shu Edson , Pinto Fernando 
Published: June 2017

Introduction Retrograde ventriculosinus shunt (RVSS) is a useful option in the daily routine of neurosurgeons dealing with hydrodynamics. The objective of this manuscript is to review the main data about RVSS.
Methods We performed a critical review. The keywords used were hydrocephalus, shunt, venous sinus, ventriculosinus shunt, retrograde ventriculosinus shunt, and sagittal sinus. The search was performed in the Medline (Pubmed) and EMBASE databases.
Results Van Canneyt et al (2008) and Pinto et al (2016) performed experimental studies confirming the effectiveness of RVSS. El Shafei et al (1985, 1987, 2001) authors reported several cases treated with efficacy and few complications. Oliveira et al (2015, 2016) compared RVSS and ventriculoperitoneal shunt (VPS) in the treatment of hydrocephalus after myelomeningocele repair in infants, with similar functional results. Oliveira et al (2015, 2016) also described the applicability of RVSS in situations when VPS is not feasible, or when the peritoneum is not useful.
Discussion Retrograde ventriculosinus shunt is a safe and more physiological option, which requires the use of less prosthetic material. It is feasible and applicable. Especially in children, it generates a normotensive state after shunting, allowing centrifugal head growth, once there is no intracranial hypotension due to overdrainage, which may reflect in long-term better psychomotor development.
Conclusions The surgical technique of RVSS is feasible. The clinical results are comparable with those of the VPS.
Qualitätskriterien in der Anwendung auf Beispiele guter Praxis in der Bewegungsförderung in
Deutschland
Authors: Henn A. , Karger C. , Wöhlken K. , Ungerer-Röhrich U. , Graf C. , Woll A. 
Published: June 2017

ZusammenfassungFür die Aufrechterhaltung von Gesundheit ist ein gewisses Maß an körperlich-sportlicher Aktivität
notwendig und das Erfüllen bestimmter Bewegungsempfehlungen unabdingbar. In Deutschland existieren daher
bereits zahlreiche Maßnahmen zur Bewegungsförderung. Ziel des Beitrags ist, exemplarisch Projekte
vorzustellen, die als „Good-Practice“-Beispiele für die Zielgruppen „Kinder und Jugendliche“,
„Erwachsene“, „ältere Menschen“, „Menschen mit Vorerkrankungen“ genannt werden können. Die Auswahl
basiert auf der Erfüllung bestimmter Qualitätskriterien. Für jede Zielgruppe wird beispielhaft ein
Bewegungsförderungsprogramm näher erläutert.
Representing Chinese nationalism/patriotism through President Xi Jinping’s “Chinese Dream” Discourse
Authors: Wang Jiayu 
Published: June 2017

Abstract
This paper analyzes the Chinese nationalism or patriotism embodied in Xi Jinping’s “Chinese Dream” discourse. It first reviews the “typological tradition” of categorizing nationalism into different types, for instance, banal, hot and cultural nationalism. Xi Jinping’s “Chinese Dream” discourse goes beyond the explanation of these distinct types of nationalism. Instead, it embodies a “hybrid” type of nationalism/patriotism that is at once banal, state, cultural, and “de-banalized”. This study adopts a dialectical-relational perspective by viewing the “Chinese Dream” discourse as representations of social practices through which politicians utilize a wide range of discursive resources including thematic, evaluative and cultural representations to evoke the imagination of a common identity in support of their governance. Through the analysis, this study advocates a holistic view of nationalism in real political practices; it also focuses on how nationalism is evoked and propagated through the integration of various discursive resources embodying a hybrid type of nationalism.
Discourse theory in populism research
Authors: Stavrakakis Yannis 
Published: June 2017

Abstract
‘Populism’ constitutes one of the most hotly debated topics in contemporary politics and academia. The concept is used to describe a series of heterogeneous phenomena: on the one hand, Donald Trump, BREXIT supporters and the European Far Right in government or in opposition; on the other, Bernie Sanders, the so-called Pink Tide of left-wing populist governments in Latin America and inclusionary populisms in the European South. Recent developments have undoubtedly generated significant research material and a new impetus to the scope and impact of populism research. However, major challenges have also been created, requiring urgent attention. This paper discusses three such challenges (reflexivity, definition, typology) from a discursive perspective. Starting from a double hermeneutic focus on the interaction between academic theorization and political orientation, it highlights the importance of discourse theory in populism research and concludes by formulating a crucial theoretico-political dilemma populism researchers are increasingly facing today.
Electrophysiological and experimental-behavioral approaches to the study of intra-sentential code-switching
Authors: van Hell Janet G. , Fernandez Carla B. , Kootstra Gerrit Jan , Litcofsky Kaitlyn A. , Ting Caitlin Y. 
Published: June 2017

Abstract
A hallmark of bilingual language processing is intra-sentential code-switching. An emergent body of research seeks to understand the intricate neural and cognitive mechanisms that underlie this seemingly effortless skill. In this paper, we discuss electrophysiological and experimental-behavioral research approaches that have been used to study intra-sentential code-switching, and illustrate the use of these techniques by discussing a select number of empirical studies. More specifically, we discuss electrophysiological approaches that are used to study the comprehension of visually and auditorily presented code-switched sentences, including the Event-Related brain Potentials (ERPs) method, time-frequency analysis, and approaches to study inter-individual variation in electrophysiological response profiles. This is followed by a discussion of experimental-behavioral techniques to study the comprehension and production of code-switched sentences, including self-paced reading, shadowing, and confederate scripting.
Substance use Education in US Schools of Pharmacy: A Systematic Review of the Literature
Authors: Muzyk Andrew J. , Peedin Emily , Lipetzky Juliana , Parker Haley , McEachern Mark P. , Thomas Kelan 
Published: June 2017

Background The authors sought to systematically review the quantity and quality of literature describing substance use disorders (SUDs) education in US schools of pharmacy and determine the effectiveness of the educational interventions employed. Methods The authors conducted a systematic review of SUDs education studies in US pharmacy schools. All literature database searches were performed on April 30, 2016, in 5 databases: Ovid MEDLINE, Ovid MEDLINE In-Process & Other Non-Indexed Citations, Embase.com , ERIC via FirstSearch, and CINAHL via EBSCOhost. The study authors conducted this systematic review according to the Preferred Reporting Items for Systemic Reviews and Meta-analyses guidelines and registered it with PROSPERO, which is an international prospective register of systematic reviews. The PROSPERO registration number is CRD42016037443. The study authors created a modified data extraction sheet based on the Best Evidence in Medical Education coding sheet. A Medical Education Research Study Quality Instrument (MERSQI) score was calculated for included articles. Results From the 1626 retrieved records, 7 were included in the present review. The studies assessed students’ impressions and abilities regarding SUDs pre- and post-intervention. The mean ± SD MERSQI score of the 7 studies was 9.86 ± 1.21 (range: 8–11.5). The included articles assessed pharmacy students at various academic years, with the majority students in either their first or second year of pharmacy school, and described both required and elective courses. The educational interventions varied in design and outcomes measured. Education included nicotine, alcoholism, and SUDs in general. None of the included articles reported on education regarding opioid use disorders. Conclusions The studies included in this systematic review demonstrate that teaching pharmacy students about SUDs produces a positive impact in their attitudes and knowledge on this subject.