bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of health education in forensic psychiatry departments
Authors: Fojcik Joanna , Górski Mchał , Krzystanek Marek 
Published: September 2024

Cel pracyPrzedmiotem badania była ocena wartości terapeutycznej autorskiego programu edukacji zdrowotnej opracowanego dla grupy pacjentów oddziałów psychiatrii sądowej prowadzonego w grupie pacjentów długotrwale izolowanych od ich naturalnego środowiska. Celem głównym badania była odpowiedź na pytanie czy edukacja zdrowotna prowadzona w oddziałach psychiatrii sądowej jest skuteczna i jaką przedstawia wartość w procesie leczenia i rehabilitacji pacjentów oddziałów psychiatrii sądowej.MetodaBadanie zostało przeprowadzone w Państwowym Szpitalu dla Nerwowo i Psychicznie Chorych w Rybniku w oddziałach psychiatrii sądowej i trwało od grudnia 2019r do maja 2020r. Podczas badania pacjenci zdobywali wiedzę z zakresu szeroko pojętej edukacji zdrowotnej. Grupę badaną stanowiło 67 mężczyzn w przedziale wiekowym od 22 – 73 lat z rozpoznaniem schizofrenii. Metodę dwukrotnych pomiarów (przed cyklem edukacji zdrowotnej i po jej ukończeniu) zastosowano przy użyciu autorskiego kwestionariusza wiedzy pacjentów z zastosowanego programu edukacyjnego.WynikiPo realizacji programu edukacji zdrowotnej nastąpiła istotna poprawa stanu wiedzy pacjentów.WnioskiDziałania edukacyjne prowadzone wśród pacjentów oddziałów psychiatrii sądowej skutecznie zwiększają poziom ich wiedzy.
First-Order Algorithms for Robust Optimization Problems via Convex-Concave Saddle-Point Lagrangian Reformulation
Authors: Postek Krzysztof , Shtern Shimrit 
Published: September 2024

Robust optimization (RO) is one of the key paradigms for solving optimization problems affected by uncertainty. Two principal approaches for RO, the robust counterpart method and the adversarial approach, potentially lead to excessively large optimization problems. For that reason, first-order approaches, based on online convex optimization, have been proposed as alternatives for the case of large-scale problems. However, existing first-order methods are either stochastic in nature or involve a binary search for the optimal value. We show that this problem can also be solved with deterministic first-order algorithms based on a saddle-point Lagrangian reformulation that avoid both of these issues. Our approach recovers the other approaches’ [Formula: see text] convergence rate in the general case and offers an improved [Formula: see text] rate for problems with constraints that are affine both in the decision and in the uncertainty. Experiment involving robust quadratic optimization demonstrates the numerical benefits of our approach. History: Accepted by Antonio Frangioni, Area Editor for Design & Analysis of Algorithms–Continuous. Funding: This work was supported by the Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Grant VI.Veni.191E.035] and the Israel Science Foundation [Grant 1460/19]. Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplemental Information ( https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2022.0200 ) as well as from the IJOC GitHub software repository ( https://github.com/INFORMSJoC/2022.0200 ). The complete IJOC Software and Data Repository is available at https://informsjoc.github.io/ .
Do Consumers Respond to Social Movements? Evidence from Gender-Stereotypical Purchases After #MeToo
Authors: Bellet Clément S. , Dubois David , Godart Frédéric 
Published: September 2024

This paper explores whether and how consumers respond to global social movements challenging systemic discrimination and stereotypes. We examine the impact of the #MeToo movement on the market for products with stereotypical markers of femininity. Our analysis of high-frequency stockout and price data from a leading global fashion retailer spans from January 2017 to December 2018 and covers 32 countries, or 89% of the Organization for Economic Cooperation and Development (OECD) population. Using a triple-difference approach across time, countries, and products, we identify changes in product-level stockouts, corresponding to a drop in the purchase of stereotypically “feminine” items. Our findings suggest a sudden shift in demand, with no immediate adjustments in product assortments or pricing. We discuss potential driving mechanisms, as well as implications for product management and marketing in marketplaces where segmentation is gender based. This paper was accepted by Yan Chen, behavioral economics and decision analysis. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.02352 .
Good Prophets Know When the End Is Near
Authors: Banerjee Siddhartha , Freund Daniel 
Published: September 2024

We consider a class of online decision-making problems with exchangeable actions, where in each period a controller is presented an input type drawn from some stochastic arrival process. The controller must choose an action, and the final objective depends only on the aggregate type-action counts. Such a framework encapsulates many online stochastic variants of common optimization problems with knapsack, bin packing, and generalized assignment as canonical examples. In such settings, we study a natural model-predictive control algorithm. We introduce general conditions under which this algorithm obtains uniform additive loss (independent of the horizon) compared with an optimal solution with full knowledge of arrivals. Our condition builds on the recently introduced compensated coupling technique, providing a unified view of how uniform additive loss arises as a consequence of the geometry of the underlying decision-making problem. Our characterization allows us to derive uniform loss algorithms for several new settings, including the first such algorithm for online stochastic bin packing. It also lets us study the effect of other modeling assumptions, including choice of horizon, batched decisions, and limited computation. In particular, we show that our condition is fulfilled by the above-mentioned problems when the end of the time horizon is known sufficiently long before the end. In contrast, if at a late stage, there is still uncertainty about the end of the time horizon we show that such uniform loss guarantees are impossible to achieve. We use real and synthetic data to illustrate our findings. This paper was accepted by J. George Shanthikumar, data science. Funding: This work was supported by the Division of Mathematical Sciences [Grant 1839346]; the Division of Electrical, Communications and Cyber Systems [Grant 1847393]; and the Army Research Laboratory [Grant W911NF-17-1-0094]. The authors also gratefully acknowledge support from the NSF [Grants ECCS-1847393, CNS-195599, and DMS-1839346], AFOSR [Grant FA9550-23-1-0068], an ARL award [Grant W911NF-17-1-0094], and ARO MURI [Grant W911NF-19-1-0217]. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2023.04307 .
Immunoglobulin G4-related spinal pachymeningitis: A case report
Authors: Chae Tae-Seok , Kim Da-Sol , Kim Gi-Wook , Won Yu Hui , Ko Myoung-Hwan , Park Sung-Hee , Seo Jeong-Hwan 
Published: September 2024

BACKGROUND
Immunoglobulin G4-related disease (IgG4-RD) is a complex immune-mediated condition that causes fibrotic inflammation in several organs. A significant clinical feature of IgG4-RD is hypertrophic pachymeningitis, which manifests as inflammation of the dura mater in intracranial or spinal regions. Although IgG4-RD can affect multiple areas, the spine is a relatively rare site compared to the more frequent involvement of intracranial structures.
CASE SUMMARY
A 70-year-old male presented to our hospital with a two-day history of fever, altered mental status, and generalized weakness. The initial brain magnetic resonance imaging (MRI) revealed multiple small infarcts across various cerebral regions. On the second day after admission, a physical examination revealed motor weakness in both lower extremities and diminished sensation in the right lower extremity. Electromyographic evaluation revealed findings consistent with acute motor sensory neuropathy. Despite initial management with intravenous immunoglobulin for presumed Guillain-Barré syndrome, the patient exhibited progressive worsening of motor deficits. On the 45th day of hospitalization, an enhanced MRI of the entire spine, focusing specifically on the thoracic 9 to lumbar 1 vertebral level, raised the suspicion of IgG4-related spinal pachymeningitis. Subsequently, the patient was administered oral prednisolone and participated in a comprehensive rehabilitation program that included gait training and lower extremity strengthening exercises.
CONCLUSION
IgG4-related spinal pachymeningitis, diagnosed on MRI, was treated with corticosteroids and a structured rehabilitation regimen, leading to significant improvement.
Fatores relacionados ao óbito por COVID-19: estudo transversal em município catarinense
Authors: Pereira Corrêa Vanessa , Reis da Silveira Edenice , Rodrigues da Luz Jaíne , Vanti da Rocha Bruna 
Published: September 2024

Objetivo: Compreender os fatores relacionados aos óbitos de Síndrome Respiratória Aguda Grave (SRAG) por COVID-19, no município de Itajaí, Santa Catarina. Métodos: Estudo transversal com dados públicos do DataSUS, sobre as hospitalizações por SRAG notificadas por ocorrência no município, entre a 1ª/2020 – 52ª/2021 semana epidemiológica. Os resultados foram expressos em frequências absolutas, relativas e razão de chance (análise de dados completos) com seus respectivos IC95%. Todas as análises foram realizadas no Stata 16.0. Resultados: De 2.297 casos de SRAG, 51,7% foram notificados como SRAG por COVID-19. O perfil dos óbitos e das hospitalizações foram semelhantes - sexo masculino (54,9%), com 60 anos ou mais (45,1%), cor da pele branca (87,4%) e com ensino fundamental (56,4%). No entanto, em análise bivariada, o estudo mostra maior frequência de óbitos naqueles que historicamente são marginalizados: negros, indígenas e pessoas de baixa escolaridade. Ser da faixa etária entre 20 e 39 anos diminuiu as chances de óbitos por SRAG por COVID-19 quando comparado à faixa etária entre 0-12 anos (OR: 0,71 (0,60-0,85).
Living donors kidney transplantation and oxidative stress: Nitric oxide as a predictive marker of graft function
Authors: Izemrane Djamila , Benziane Ali , Makrelouf Mohamed , Hamdis Nacim , Rabia Samia Hadj , Boudjellaba Sofiane , Baz Ahsene , Benaziza Djamila 
Published: September 2024

Background
Glomerular filtration rate is the best indicator of renal function and a predictor of graft and patient survival after kidney transplantation.

Methods
In a single-centre prospective analysis, we assessed the predictive performances of 4 oxidative stress biomarkers in estimating graft function at 6 months and 1 year after kidney transplantation from living donors. Blood samples were achieved on days (D-1, D1, D2, D3, D6 and D8), months (M1, M3 and M6) and after one year (1Y). For donors, a blood sample was collected on D-1. Malondialdehyde (MDA), nitric oxide (NO), glutathione s-transferase (GST), myeloperoxydase (MPO), and creatinine (Cr) were measured by spectrophotometric essays. The estimated glomerular filtration rate by the modification of diet in renal disease equation (MDRD-eGFR) was used to assess renal function in 32 consecutive donor-recipient pairs. Pearson’s and Spearman’s correlations have been applied to filter out variables and covariables that can be used to build predictive models of graft function at six months and one year. The predictive performances of NO and MPO were tested by multivariable stepwise linear regression to estimate glomerular filtration rate at six months.

Results
Three models with the highest coefficients of determination stand out, combining the two variables nitric oxide at day 6 and an MDRD-eGFR variable at day 6 or MDRD-eGFR at day 21 or MDRD-eGFR at 3 months, associated for the first two models or not for the third model with donor age as a covariable (P = 0.000, r2 = 0.599, r2adj = 0.549; P = 0.000, r2 = 0.548, r2adj = 0.497; P = 0.000, r2 = 0.553, r2adj = 0.517 respectively).

Conclusion
Quantification of nitric oxide at day six could be useful in predicting graft function at six months in association with donor age and the estimated glomerular filtration rate in recipient at day 6, day 21 and 3 months after transplantation.
Perioperative PD-1/PD-L1 inhibitors for resectable non-small cell lung cancer: A meta-analysis based on randomized controlled trials
Authors: Huang Hai , Li Lianyun , Tong Ling , Luo Houfu , Luo Huijing , Zhang Qimin 
Published: September 2024

Background
PD-1/PD-L1 inhibitors (PI) have shown promising results in both neoadjuvant and adjuvant therapies for resectable non-small cell lung cancer (NSCLC). However, substantial evidence from large-scale studies is still lacking for their use in the perioperative setting (neoadjuvant plus adjuvant). This meta-analysis aims to evaluate the integration of perioperative PI (PPI) with neoadjuvant chemotherapy for resectable NSCLC.

Methods
To identify appropriate randomized controlled trials (RCTs), we thoroughly explored six different databases. The primary endpoint was survival, while the secondary measures included pathological responses and adverse events (AEs).

Results
Six RCTs involving 2941 patients were included. The PPI group significantly improved overall survival (OS) (hazard ratio [HR]: 0.62 [0.51, 0.77]), event-free survival (EFS) (HR: 0.57 [0.51, 0.64]), pathological complete response (risk ratio [RR]: 5.81 [4.47, 7.57]), and major pathological response (RR: 2.60 [1.77, 3.82]). Benefits in EFS were seen across all subgroups. OS rates at 12–48 months and EFS rates at 6–48 months were higher in the PPI cohort. Furthermore, the advantages in OS and EFS increased with prolonged survival times. The PPI group also exhibited higher rates of surgery and R0 resections. However, the PPI group experienced more grade 3–5 AEs, serious AEs, and treatment discontinuations due to AEs.

Conclusions
The integration of perioperative PI with neoadjuvant chemotherapy can significantly improve survival and pathological responses for resectable NSCLC. However, the increased incidence of grade 3–5 AEs must be carefully evaluated.
Dynamics of Splenic Transient Elastography in Patients With Alcohol Use Disorder
Authors: Khalid Mian B. , Blaney Hanna L. , Vittal Anusha , Yang Alexander H. , Asif Bilal A. , Kamal Natasha , Wright Elizabeth C. , Koh Chris , George David , Goldman David , Horneffer Yvonne , Diazgranados Nancy , Heller Theo 
Published: September 2024

INTRODUCTION:
Splenic stiffness (SS) measurement (SSM) is an evolving noninvasive assessment to evaluate portal hypertension. Studies with respect to SSM in patients with alcohol use disorder are limited.

METHODS:
We studied patients seeking treatment for alcohol use disorder in an inpatient treatment protocol at the National Institutes of Health and parsed SSM into 3 groups based on degree of change.

RESULTS:
The improved SS group had statistically higher initial SSM and a nonstatistically increased liver stiffness measurement compared with others.

DISCUSSION:
SS is dynamic in a subset of patients immediately after alcohol cessation, and improved SS is associated with a normalization of platelet count.
Academic and Research Libraries in Italy from Past to Future
Authors: Fontana Antonia Ida , Mataloni Maria Cristina , Morriello Rossana 
Published: September 2024

Abstract
In Italy academic and research libraries were invigorated in the 1990s and again in the 2000s. These years include the automation of catalogues, the development of the National Library Service (SBN), the birth of consortia to deal with organizational and management needs introduced by the digital library with the birth of the World Wide Web and the paradigm shift from ownership to access. The article outlines the main stages of this path at a technological, organizational, legislative, and professional development level up to more recent times in which the vitality of those years seems increasingly more difficult to achieve, despite being crucial to face the challenges raised by the growing complexity of the digital information context.
Macrofungal sporocarp community in the lichen Scots pine forests
Authors: Grzesiak Barbara , Węgrzyn Michał Hubert , Turowska Agnieszka , Twarużek Magdalena 
Published: September 2024

Abstract
The lichen-rich pine forests of Cladonio-Pinetum represent special habitats protected under the Natura 2000 scheme. A rapid decline in their density has been observed in recent years. Macrofungi are an important component of the community and sensitive bioindicators; therefore, observations of the response of their sporocarps can be used to draw conclusions about changes induced in habitats. In our study, we tried to detect differences in species richness, composition, and biomass of the ectomycorrhizal fungal communities in areas rich in lichens indicating the good state of the community, and rich in bryophytes signaling its progressive degradation. The influence of precipitation and temperature on species richness and biomass was checked, and the possibility of using the sporocarps-based method to assess the effectiveness of active protection treatments, which are a form of partial protection carried out to maintain specific natural habitats. For detailed studies, six plots were selected from which sporocarps were collected, dried and weighed. A total of 1,575 sporocarps, representing 49 taxa were collected. A higher number of taxa (39) in lichen-rich plots were found. In bryophyte-rich areas, 27 taxa were recorded. The total yield was 13,151 g dry weight ha−1. In lichen-rich plots, the biomass was almost half lower.
Agreement of lymphocyte subsets detection permits reference intervals transference between flow cytometry systems: direct validation using established reference intervals
Authors: Liu Mei , Yu Sihua , Li Siyao , Yu Xiaowen , Wang Heqiao , Wang Jiaqi , Wang Pan , Su Zihan , Fu Yajing , Jiang Yongjun , Zhao Min , Zhang Zining , Shang Hong 
Published: September 2024

Abstract

Objectives
With the increasing demand and application of lymphocyte subsets detection in clinical laboratories, different single-platform flow cytometer (FCM) systems have been developed. There is an urgent need to establish the reference intervals (RIs) for different single-platform FCMs and transferring them from one FCM system to another provides a much more feasible and convenient approach. This study aimed to explore the transferability of RIs for lymphocyte subsets across different flow cytometry platforms.

Methods
We first conducted the pairwise method comparison across four FCM platforms, including NovoCyte, BriCyteE6, DxFLEX, and FACSCantoII systems. Next, the transferability of RIs of lymphocyte subsets was evaluated. Furthermore, we conducted the RIs transference based on the FACSCantoII system, BriCyteE6 system and DxFLEX system, except for NK cells. The transferred RIs were further verified by calculating the bias (CV) between the established ones.

Results
The results of lymphocyte subsets detection based on the NovoCyte, BriCyteE6, DxFLEX, and FACSCantoII systems were comparable and it was feasible to transfer the RIs of lymphocyte subsets detected by the four FCM systems. The RIs of lymphocyte subsets detection using FACSCantoII, DxFLEX, and BriCyteE6 systems were established. Upon transferring the RIs of lymphocyte subsets from the FACSCantoII system to the BriCyteE6 system, and DxFLEX system except for NK cells, the CV between the transferred RIs and the established ones was below 20 % for all parameters.

Conclusions
The present study illustrated that the RIs of lymphocyte subsets could be transferred across different flow cytometry systems except for NK cells with different definition strategies.
Antioxidant and antidiabetic potentials of methoxy-substituted Schiff bases using in vitro, in vivo, and molecular simulation approaches
Authors: Kashif Muhammad , Naz Sumaira , Zahoor Muhammad , Shah Syed Wadood Ali , Uddin Jalal , Esa Muhammad , ur Rashid Haroon , Ullah Riaz , Alotaibi Amal 
Published: September 2024

Abstract
The current study attempted to synthesize methoxy-substituted Schiff’s bases, namely MK1 and MK2, and evaluate their antidiabetic effects using in vitro, in vivo, and molecular docking studies. Experimental animals (rat model) received the synthetic compounds, MK1 and MK2, orally in doses of 25 and 50 mg/kg body weight, respectively. When comparing compound MK2 at the tested doses to glibenclamide on day 28, the diabetic rats’ blood glucose levels were nearly normal (139.02 and 121.23 mg/dL at 25 and 50 mg/kg body weight doses). The IC50 for MK1 against α-glucosidase inhibitory potential was found to be 281.29 μg/mL, while for MK2, it is reported to be 204.69 μg/mL. Furthermore, the acute toxicity, lipid profile, and its effect on blood biochemical parameters were also examined. In addition, through in silico analysis, the binding of MK1 and MK2 was elucidated with α-glucosidase enzyme, showcasing its antidiabetic mechanism at molecular levels. The in silico studies also predicted the two compounds to be inactive toward the human hERGs cardiac potassium channel, which indicates no potential risk of cardiac toxicity. Overall, the toxicity predictions suggest that compounds MK1 and MK2 are non-toxic and non-carcinogenic.
Investigation of DG units influence on 66 kV sub-transmission system network considering region load growth: a case study
Authors: Sultan Adel S. , Abdelaziz Almoataz Y. , Attia Mahmoud A. , Ray Papia 
Published: September 2024

Abstract
Voltage breakdown in sub-transmission networks resulting from an increase in load demand can be addressed by incorporating distributed generation (DG) units such as hydro, wind, photovoltaic, and geothermal in some buses. This approach can lower power losses and the price of the primary generated energy while increasing network dependability and efficiency. Feasibility of dispersed generation integration & its effect on sub-transmission system operation were investigated using Ben Walied 66 kV sub-transmission network in Libya as a state. This study presents modified particle swarm optimization (MOPSO) technique to select the best option with dispersed generation units under various operating conditions. The Ben Walied 66 kV sub-transmission network has been subject of effects research on both normal operation and load growth scenarios. The goal of this study was to find best way to adjust penetration level of the three DGs in response to changes in the network loading. Three DG units have been refitted to study the effects on test networks for sub-transmission, which consist of 30 and 51 buses. A comparison analysis shows that while the ideal locations of DG units remain constant with load expansion, the optimal solution for the penetration level percentage of three DG units was boosted by new optimal sizes. Research has been done on how the power factor of distributed generators (DGs) affects the practical performance of 66 kV networks in steady-state conditions. The integration of DG units in regulating these losses and voltage variations is demonstrated by the results, which indicate that the ideal solution for DG unit’s power factor was at a value of 0.87 lagging.