bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autogenous platelet concentrates for treatment of intrabony defects—A systematic review with meta‐analysis
Authors: Miron Richard J. , Moraschini Vittorio , Estrin Nathan , Shibli Jamil Awad , Cosgarea Raluca , Jepsen Karin , Jervøe‐Storm Pia‐Merete , Wang Hom‐Lay , Sculean Anton , Jepsen Søren 
Published: October 2024

AbstractTo provide an overview of the use of autogenous platelet concentrates (APCs) in periodontal regeneration and to conduct a systematic review (SR) of the treatment outcomes of periodontal intrabony defects by using platelet‐rich fibrin (PRF) compared with other commonly utilized modalities. The eligibility criteria comprised randomized controlled trials (RCTs) comparing the clinical outcomes of PRF with that of other modalities. Studies were classified into 21 categories and into five different groups as follows: Group I (1) open flap debridement (OFD) alone versus OFD/PRF, (2) OFD versus Titanium‐PRF (T‐PRF) Group II, (3) Comparative PRF protocols (PRF vs. T‐PRF), Group III (Comparative Studies to PRF): (4) OFD/PRP versus OFD/PRF, (5) OFD/bone graft(BG)/PRGF versus OFD/BG/PRF, (6) OFD/EMD versus OFD/PRF, (7) OFD/BG/EMD versus OFD/BG/PRF, (8) OFD/collagen membrane (CM) versus OFD/PRF, (9) OFD/BG/BM versus OFD/BG/PRF, (10) OFD/BG versus OFD/PRF, Group IV (Addition of PRF to treatment groups) (11) OFD/BG versus OFD/BG/PRF, (12) OFD/GTR versus OFD/GTR + PRF (13) OFD/EMD versus OFD/EMD/PRF (14) OFD/BG/BM versus OFD/BG/BM/PRF, Group V (Addition of Biomaterial/Biomolecule to PRF): OFD/PRF versus … (15) OFD/PRF/BG, (16) OFD/PRF/antibiotic, (17) OFD/PRF/Metformin, (18) OFD/PRF/Bisphosphonates, (19) OFD/PRF/Statins, (20) OFD/BG/PRF versus OFD/BG/PRF/Statins, and (21) OFD/PRF/low‐level laser therapy (LLLT). Weighted means and forest plots were calculated for probing pocket depth (PPD), clinical attachment level (CAL), and radiographic bone fill (RBF). From 596 records identified, 55 RCTs were included. Group I: The use of OFD/PRF statistically significantly reduced PPD and improved CAL and RBF when compared to OFD. Group II: A significant difference between various PRF protocols was only observed for PPD. Group III: No significant advantage was found when comparing OFD/PRF to the following groups: OFD/PRP, OFD/EMD, OFD/BM, or OFD/BG. Group IV: The addition of PRF to OFD/BG led to significant improvements in PPD, CAL and RBF compared with OFD/BG alone. Group V: The addition of either a BG as well as three of the following biomolecules (metformin, bisphosphonates, and statins) to OFD/PRF led to statistically significant improvements in PPD, CAL, and/or RBF when compared to OFD/PRF alone. The use of PRF significantly improved clinical outcomes in intrabony defects when compared to OFD alone. Similar results were observed when OFD/PRF was compared with OFD/BG, OFD/EMD, OFD/PRP, and OFD/BM. The addition of PRF to a bone grafting material as well as the addition of various small biomolecules to PRF may offer additional clinical advantages, thus warranting further investigations. Future research investigating various protocols of PRF, longer‐term outcomes, as well as PRF at the human histological level remains needed.
An adaptation and validation of disaster resilience scale based on community engagement theory
Authors: Gokmenoglu Tuba , Dasci Sonmez Elif 
Published: October 2024

AbstractThis study aimed to adapt and validate the Disaster Resilience Scale, originally developed by Becker et al. and revised by Paton et al., for assessing disaster resilience within the Turkish school community with a focus on Community Engagement Theory. This theory emphasizes the role of community involvement in disaster resilience at various levels, including the individual, community, and societal/institutional. The study was conducted in two phases. In the first phase, data from 428 teachers were analyzed to assess the validity and reliability of the scale's Turkish version and its alignment with dimensions. In the second phase, data from 1,422 teachers were used to further verify the reliability of using the Generalizability Theory test, and confirm validity through confirmatory factor analysis. The results confirmed that the Turkish version of the scale, with its 12 factors and 52 items was valid and reliable. Cronbach's Alpha coefficients for the dimensions ranged from 0.80 to 0.91, indicating high reliability. The findings highlight the practical implications of adapting the DRS for enhancing disaster resilience in school communities and underscore the importance of community engagement in disaster preparedness and education.
Assessment of structural and functional profile of dental centers for people with disabilities
Authors: Dua Kirti , Miglani Sanjay , Katyal Sakshi , Batra Panchali 
Published: October 2024

AbstractAimsPeople with disabilities (PWD) often face more significant oral healthcare needs than the general population. This study, conducted in response to the urgent and pressing need for improved dental care for PWD, aims to assess the infrastructural and work process flow of dental centers in Delhi that provide specialized dental care for PWD.Methods and resultsA descriptive cross‐sectional study was conducted across primary, secondary, and tertiary healthcare centers in Delhi, evaluating their infrastructure adaptations and work processes in delivering oral healthcare to PWD. The findings, which highlight the disparities in adaptations and work processes among different healthcare centers, are crucial for understanding the current state of oral healthcare for PWD in Delhi. The study reveals that while secondary and tertiary healthcare centers exhibit better adaptations for PWD than primary centers, challenges persist with insufficient accessibility and smooth functioning of the work process.ConclusionThis study underscores the need for dentists to be equipped with the competence to address the unique needs of PWD. It also highlights the significant potential for improvement in oral healthcare for PWD, as dentists should become more aware of the importance of designing clinics that are accessible for PWD.
Fitness, Gray Matter Volume, and Executive Function in Cognitively Normal Older Adults: Cross‐Sectional Findings From the AGUEDA Trial
Authors: Coca‐Pulido Andrea , Solis‐Urra Patricio , Fernandez‐Gamez Beatriz , Olvera‐Rojas Marcos , Bellón Darío , Sclafani Alessandro , Toval Angel , Martín‐Fuentes Isabel , Bakker Esmée A. , Fernández‐Ortega Javier , Gomez‐Rio Manuel , Hillman Charles H. , Erickson Kirk I. , Ortega Francisco B. , Mora‐Gonzalez Jose , Esteban‐Cornejo Irene 
Published: October 2024

ABSTRACTThe aim of the study is to investigate the association of cardiorespiratory fitness (CRF) and muscular strength indicators with gray matter volume (GMV) and to study whether fitness‐related regions of GMV are associated to executive function (EF) in cognitively normal older adults. Ninety‐one cognitively normal older adults (71.69 ± 3.91 years; 57.14% females) participated in this study from the AGUEDA trial. CRF was measured by a 2‐km walking test and a 6‐min walking test. Muscular strength was measured by handgrip, biceps curl, squats, and isokinetic strength tests. T1‐weigthed images were obtained through a magnetic resonance scan. GMV was determined by voxel‐based morphometric analysis. Standardized EF tests were performed. CRF did not show any positive association with GMV. Handgrip strength was positively associated with GMV (p < 0.001) in nine regions (β from 0.6 to 0.8 and k from 106 to 1927) and knee extension strength in three regions (β from 0.4 to 0.5 and k from 76 to 2776). Squats strength was negatively associated with GMV (p < 0.001) in two regions (β = −0.3, k = 1102 and k = 152) and the 2‐km walking test in one region (β = −0.4, k = 99). Only handgrip strength‐related GMV was associated with cognitive flexibility (p = 0.039, β = 0.215) and spatial working memory (p < 0.03, β 0.247–0.317), but not with EF score (p > 0.05). Muscular strength, but no CRF, may be positively related to GMV in cortical and subcortical regions, with implications for specific cognitive domains rather than the overall EF score. Specifically, handgrip strength was the indicator most associated with higher GMV, while squats strength and CRF were negatively related to GMV.ClinicalTrials.gov identifier: NCT05186090.
NUMERICAL AND EXPERIMENTAL RESEARCH ON THE DI-CI ENGINE PERFORMANCE CHARACTERISTICS UNDER LPG - DIESEL DUAL FUEL COMBUSTION MODE
Authors: Tan Chau Vo , Vu Truong Giang Hoang , Huynh Giang Luong , Quoc Sy Nguyen 
Published: October 2024

Properties of Liquefied Petroleum Gas (LPG) are suitable as an alternative fuel for internal combustion engines. This work aims to combine both numerical optimization analysis of LPG injector placement angle and subsequent experiment with selected mounting injector angle to investigate the effects of using LPG as a parallel-partial substitute fuel with diesel fuel under dual-fuel combustion mode. An electronic injection fuel control system was applied to the modified intake manifold to generate the appropriate LPG injection. Three mounting angle injector positions including 450, 900 and 1350 in the upstream direction of intake air have been defined by Ansys Fluent to take into account efficient LPG-air mixing. Then, the experiment was conducted with LPG-diesel dual-fuel combustion mode (DFC mode) and compared to entirely diesel combustion mode as baseline data. Different load conditions ranging from idle to 4.0 kW were imposed at a constant engine speed of 1700rpm. The obtained results revealed that the injector’s mounting angle position by 45 opposite to the intake air flow showed the correlation with the calculated LPG-air ratio in dual fuel combustion reaction. In DFC mode, the brake thermal efficiency (BTE) decreased on average by 4.6% and the LPG substitution rate gradually decreased while brake-specific fuel consumption (BSFC) increased for all engine loads. The exhaust temperature in the dual-fuel combustion mode was found to be higher than that of full diesel fuel mode at low loads (less than 2.5 kW) and began to decrease at higher loads.
Multi-State Reliability Modeling and Assessment for Corrosion of Organic Coating-Substrate Structure
Authors: Xie Chaoyang , Zhang Hao 
Published: October 2024

Abstract
The organic coating-substrate structure suffers from corrosion reaction between the substrate material and water molecules during the storage stage. Multiphysics simulation is a promising tool for corrosion modeling and assessing the reliability of the organic coating-substrate structure. In this paper, a multistate modeling method is proposed toward the reliability modeling and assessment. First, to analyze the physicochemical process involved in the corrosion of organic coating-substrate structures, a multiphysics simulation method is developed. Then, the degradation performance of the organic coating-substrate structure is discretized into several states, and a Markov model is utilized to model the degradation process of the structure. The transition intensities of the Markov model are estimated by using the multiphysics simulation data. In the proposed method, the multiphysics simulation method can incorporate the diffusion equation and the kinetic equation of the corrosion, allowing for the simulation of water molecule diffusion within the organic coating and the coupling simulation of the metal corrosion process. Subsequently, the reliability of the organic coating-substrate structure is analyzed under varying temperatures, humidity levels, and protective material parameters. The result shows that higher ambient temperatures and relative humidity levels contribute to an accelerated corrosion rate of the substrate, and the reliability decreases.
Use of a Porcine Cadaver Model as a Human Surrogate for Behind Armor Blunt Trauma
Authors: McMahon Justin , Berthelson Parker , Eaton Madelyn , Lorente Ana , Leite Trevor , McEntire B. Joseph , Salzar Robert 
Published: October 2024

Abstract
Current body armor design evaluation is based on legacy backface deformation criteria for protection despite limited medical basis. This uniform protection approach, which does not account for anatomical and physiological variability within the torso, may result in heavy armors that limit Warfighter mobility. To optimize armor design, anatomical and physiological regional injury tolerances must be assessed through live animal experimentation. Prior to this, the animal and human must first be compared to determine the animal model's viability as a surrogate for thoracoabdominal behind armor blunt trauma (BABT) response. Here, 74 BABT impacts were conducted using ten midsized male postmortem human subjects (PMHS) and ten 40-kg porcine cadavers in matched testing conditions over the lungs, liver, and sternum. Injury risk functions were generated from experimental data and compared across surrogates at each body region. The PMHS and 40-kg porcine cadaver correlated well for chest wall injuries in the lung region, and similarities were noted in high-severity impacts to the liver. Further, assessment of the backface intrusion injury risk function showed regional tolerance differences between anatomical regions, highlighting the need for separate region-specific design criteria. These results indicate that the 40-kg porcine cadaver was an appropriate torso surrogate for certain PMHS regions, such as the ribcage overlaying the lungs and the liver, in BABT conditions. As this study used cadaveric tissue, future studies should investigate the physiological components of BABT-induced injury in a live animal model, focusing on quantifying regional injury tolerances toward armor design optimization.
HANNES: A Modular Neurointerventional Training Model
Authors: Schmiech Jonte , Wegner Marie , Wortmann Nadine , Sobirey Eve , Guerreiro Helena , Kyselyova Anna , Ramdani Nora , Krause Dieter 
Published: October 2024

Abstract
This work introduces version 2.0 of the Hamburg ANatomical NEurointerventional Simulator (HANNES): a novel modular neurointerventional simulator designed to provide a realistic platform for simulating various neurovascular pathologies and their endovascular therapies. Collaboratively developed by physicians and engineers, the neurointerventional simulator is designed with a modular product architecture combining standardized and variant modules to represent different training scenarios. The additively manufactured patient-based and patient-specific blood vessel tree consists of up to 13 individual components, including standardized features and interfaces for ease of connection. Patient-specific vessel models derived from medical imaging data allow customization and complexity adjustment. HANNES supports diverse neurointerventional training scenarios, including various modalities of aneurysm embolization, internal carotid artery (ICA)-stenosis, and thrombotic vessel occlusions, which can be treated through a transradial or transfemoral approach. The use and benefits of the model were evaluated with a group of trainees, who provided positive feedback, confirming the model's practicality and effectiveness in enhancing neurointerventional technical skills. In conclusion, HANNES represents a significant advancement in neurointerventional training, addressing the limitations of traditional training methods by simulating diverse disease patterns, enhancing medical staff's skills, and facilitating product testing.
Modified Centroid of Root Projection Method for Determining the Center of Resistance of a Tooth
Authors: Wang Jianing , Premaraj Thyagaseely Sheela , Premaraj Sundaralingam Prem , Gu Linxia , Dong Pengfei 
Published: October 2024

Abstract
Center of resistance (CR) has been widely accepted in dentistry as a reference point for controlling tooth moment, which depends on the direction of loading and the morphology of the periodontal ligament (PDL). In clinical practice, dentists estimate the location of CR based on the morphology of the root of teeth, which may lead to a misestimation of orthodontic treatment. A quick method was proposed to efficiently determine the CR by identifying the centroid of the root projection (CRP), according to the orthodontic force. However, the original CRP method was limited to single-rooted teeth, and it did not provide a strategy for handling the overlapping roots projection of multirooted teeth. To address this issue, we expanded the CRP method to accommodate multirooted teeth by calculating a weighted average of each root’s projection. We further validated the modified CRP method using finite element analysis (FEA) simulation for both single-rooted and multirooted teeth considering mesial–distal and buccal–lingual force directions. The evaluation of displacement distribution along the projection direction allowed us to assess translation and rotation movements, which confirmed that the centroid of root projection can accurately serve as the CR for the multirooted teeth. Additionally, we observed heterogeneous stress distributions in the multirooted teeth. Considering the well-acknowledged bone remodeling effect in response to local stress states, this indicated that comprehensive indexes beyond the CR are desired for evaluating or controlling tooth movement.
Quantifying patient satisfaction with process metrics using a weighted bundle approach
Authors: Riebling Nancy B , Norouzzadeh Shaghayegh , Reeder George , Mouradian Christina , Hillier Alison , Cowan Ryan , Doerfler Martin 
Published: October 2024

BackgroundCurrent patient satisfaction assessment results are delayed and obtained from select patient surveys. As a result, these assessments may not represent the experience of the entire patient population. This study developed a method to measure and evaluate all patients’ experiences while they are within the care episode and link it to processes within the organisation.MethodsUsing the Six Sigma methodology, sites assembled diverse teams to categorise and analyse negative experience comments from patients to understand the drivers of dissatisfaction. These customer expectations lead to the development of the four components in the Patient Experience Bundle (PEB): communication, environment, basic needs/comfort and logistics. Individual process elements were ranked to create a numerical relationship between service and the needs expressed by the voice of the customer. Sites created surveys incorporating questions that focused on the bundle elements and measured daily bundle compliance. Graphical analysis and hypothesis testing enabled sites to determine key drivers of patient dissatisfaction within the bundle elements. Improvement strategies were developed and implemented to address the key drivers of patient dissatisfaction.ResultsAfter implementing process improvements focused on issues identified by the PEB, bundle compliance improved from an average of 51% to an average of 82.5% and Press Ganey Likelihood to Recommend (PG LTR) scores improved from an average of 64.73% to an average 74.64%. The data demonstrated that the trends in improving PEB are followed by meaningful changes in PG LTR scores.ConclusionThis work is built on the identification of common elements of care that impact patient satisfaction and detailed mathematical analysis of the relationship between factors. Using the bundle concept, these improvement efforts maintain highly reliable processes to drive outcomes and provide real-time feedback on patient experience.
Cluster Headache Decreases Life Expectancy: A Longitudinal Assessment During 40 Years in a Headache Clinic Cohort
Authors: Madera Jorge , Pascual Julio , Pérez-Pereda Sara , Muñoz Pedro , González-Quintanilla Vicente 
Published: October 2024

Background: Cluster headache (CH) is one of the most disabling primary headaches. Nowadays, it is unknown if it has an impact on reducing life expectancy.Methods: We calculated years of potential life lost (YPLL) in deceased individuals from a CH registry of a third‐level hospital, using as cutoff the estimated life expectancy for our general population according to their sex and year of death. Furthermore, a descriptive and comparative analysis of the main causes of death, risk factors, and toxic habits was carried out.Results: There were 25 deaths among the 152 individuals included. Twenty‐one (84%) died earlier than expected with a mean of 9.14 YPLL (p = 0.001). Cancer was the most common cause of death in CH patients (64% of deaths vs. 28.5% expected in general population, p ≤ 0.001). Eighty percent and 45% of our deceased patients were smokers and 60% and 45% regular alcohol consumers at the diagnosis of CH and at death, respectively. The percentage of smokers at diagnosis was significantly higher than that in the reference population (80% vs. 33.2%, p < 0.001). There was a significantly higher frequency of arterial hypertension (76% vs. 19.82%, p < 0.001) and diabetes mellitus (40% vs. 7.8%, p < 0.001) at death in CH individuals compared to general population.Conclusions: CH implies a loss of almost one decade of life expectancy by an increase in cancer deaths. Tobacco and alcohol consumption seem to be the main underlying causes. These results call for an action plan for a better management of CH patients since their diagnosis.
Anatomical Variations of the Gallbladder and Bile Ducts: An MRI Study
Authors: Yason Kigundu , Gonza Kirum Gonzaga , Michael Okello , William Buwembo , Munabi Ian , Michael Kawooya 
Published: October 2024

Background: The anatomy of the biliary tree is complex with anatomical variations which can be found in ~50% of the patients.Purpose: Existing research on these variations primarily stems from studies in developed countries, with uncertain applicability to the Ugandan population due to noted ethnic differences in incidence rates.Objective: The study was aimed at describing the anatomical variations of the gallbladder and bile ducts.Methods: This retrospective cross‐sectional study conducted at Kampala MRI Centre from January 2017 to December 2022 analyzed MRCP images and reports from 231 patients to document gallbladder and bile duct variations.Results: 53.2% of patients exhibited typical cystic duct anatomy, and 51% had Type 1 variations in intrahepatic ducts. Importantly, the study identified a significant correlation between age and common bile duct diameter.Conclusion: The findings showed various anatomical variations that were slightly higher in the study population than those reported in the literature. This study emphasizes the critical need for comprehensive knowledge to enhance surgical safety, minimize iatrogenic trauma, and improve the accuracy of diagnostic imaging and hepatobiliary procedures.