bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Analysis of the Structures People With Shoulder Pain Recall After Receiving Their Diagnostic Imaging Results
Authors: Brotman Yotam B. , Malliaras Peter , Farlie Melanie K. 
Published: September 2024

ABSTRACTAimsRotator cuff related shoulder pain (RCRSP) is a prevalent cause of musculoskeletal pain. Patients presenting with this condition often undergo diagnostic imaging. However, many patients appear to have difficulty recalling the nature of their diagnosis. This may impact their rehabilitation outcomes. The aim of this study was to explore peoples' recall of their structural features relating to RCRSP by comparing their recalled description of their condition with the contents of their imaging reports as reported in an online questionnaire. In doing so, we aim to explore the potential emphasis they place on structural features related to their condition.MethodsThis study was a content analysis embedded within a larger survey study published previously. Data containing patients' recall of their diagnosis was used from the study, and analysed using content analysis to quantify content in terms of codes and categories. The aims of frequency, completeness and accuracy of recall were then explored.ResultsThe analysis identified eight categories of terminology either recalled by patients or reported in imaging reports. The most frequent categories in reports were tendinopathy (71%) and joint (67%), but only 17% and 36% of participant responses contained these codes, respectively. Participants' completeness of recall compared with their imaging report was 30% on average. In terms of accuracy, only 8 out of 95 participants recalled their diagnoses 100% correctly.ConclusionThis study indicates that patients have poor overall recall of their RCRSP‐related structural features. We contend that participants may have been able to recall what they viewed to be the most prominent structural feature in their imaging findings. It may be important for clinicians to consider the impact of diagnostic labelling, and whether a patient's ability to recall such labelling may have an influence on their outcomes.
NADPH oxidases in healthy white adipose tissue and in obesity: function, regulation, and clinical implications
Authors: Jornayvaz François R. , Gariani Karim , Somm Emmanuel , Jaquet Vincent , Bouzakri Karim , Szanto Ildiko 
Published: September 2024

AbstractReactive oxygen species, when produced in a controlled manner, are physiological modulators of healthy white adipose tissue (WAT) expansion and metabolic function. By contrast, unbridled production of oxidants is associated with pathological WAT expansion and the establishment of metabolic dysfunctions, most notably insulin resistance and type 2 diabetes mellitus. NADPH oxidases (NOXs) produce oxidants in an orderly fashion and are present in adipocytes and in other diverse WAT‐constituent cell types. Recent studies have established several links between aberrant NOX‐derived oxidant production, adiposity, and metabolic homeostasis. The objective of this review is to highlight the physiological roles attributed to diverse NOX isoforms in healthy WAT and summarize current knowledge of the metabolic consequences related to perturbations in their adequate oxidant production. We detail WAT‐related alterations in preclinical investigations conducted in NOX‐deficient murine models. In addition, we review clinical studies that have employed NOX inhibitors and currently available data related to human NOX mutations in metabolic disturbances. Future investigations aimed at understanding the integration of NOX‐derived oxidants in the regulation of the WAT cellular redox network are essential for designing successful redox‐related precision therapies to curb obesity and attenuate obesity‐associated metabolic pathologies.
Relationship between surfactant content and the properties of microfibrillated cellulose/high density polyethylene composites
Authors: Yang Xiaohui , Wang Weihong , Long Mei , Xiang Li , Cao Yan , Hao Jianxiu 
Published: September 2024

AbstractMicrofibrillated cellulose (MFC) was uniformly dispersed in high‐density polyethylene (HDPE) using a large amount of surfactant, and composites were prepared after removing the surfactant at different contents. The structural, morphological, thermal, and tensile properties of these composites were systematically investigated. The results demonstrated an asymptotic relationship between the amount of surfactant removed and the number of removal cycles. A negative linear correlation was observed between the surfactant content and the tensile strength, tensile modulus, and storage modulus at −20 °C of the composites, while a positive linear correlation was found with the loss modulus at −20 °C. Excessive surfactant adversely affected the dispersion of MFC, as well as the mechanical properties and thermal stability of the composites. However, when the surfactant content was below 2.8%, its impact on the composite properties was minimal, and the tensile strength, modulus, and thermal stability of the composites were significantly improved compared to neat HDPE. These findings indicate that surfactant pretreatment is an effective strategy for dispersing MFC in non‐polar polymers, and controlling the surfactant content in the final product can effectively tailor the properties of the resulting composites.Highlights
Confirms the relationship between surfactant content and MFC/HDPE composite properties.
Surfactant content showed an asymptotic relationship with removal cycles.
Surfactant content and mechanical properties exhibited a negative linear correlation.
Surfactant content and thermal stability exhibited a negative relationship.
Surfactant content had minor impact when below 2.8%.
Simple preparation of ultra‐thin white g‐C3N4 nano‐sheets and their use as nanofillers to enhance the tribological properties of epoxy composite coating
Authors: Li Xiang , Zhang Xiaoni , Chen Beibei , Chen Kai 
Published: September 2024

AbstractGraphite phase carbon nitride (g‐C3N4) has shown great promise as a functional filler in the field of friction. But at present, research in the field of friction mainly focuses on bulk g‐C3N4 or obtaining g‐C3N4 nano‐sheets through inefficient exfoliation strategies, which greatly limits its industrial applications. In the study, a simple and effective secondary calcination method has been developed to successfully fabricate ultrathin white g‐C3N4 nano‐sheets. The mass ratio of the same volume of bulk g‐C3N4 and white g‐C3N4 nano‐sheets was as high as 50:1. Subsequently, the tribological performance of epoxy (EP) composite coatings containing different contents of bulk g‐C3N4 and g‐C3N4 nano‐sheets were researched. The EP composite coatings containing 1 wt.% g‐C3N4 nano‐sheets possess the lowest wear rate and friction coefficient in all samples, which is attributed to the two‐dimensional planar structure and high specific surface area of g‐C3N4 nano‐sheets make it easier to transfer to the dual surface to form the excellent transfer film under the action of friction force, so that the friction mainly occurs between a dual surface and a transfer film, which effectively improves the tribological performance of the coatings.Highlights
Ultrathin white g‐C3N4 nano‐sheets were prepared by secondary calcination.
EP‐1 wt.% g‐C3N4 nanosheets show the best tribological properties.
g‐C3N4 nanosheet is easy to transfer to dual surfaces to form transfer films.
This work provides guidance for the application of nanofillers in tribology.
‘I Live With Lynch. Cancer Worry Ebbs Into the Background, Then Something Brings It to the Fore.’ A Qualitative Interview Study Exploring How Lynch Syndrome Carriers Make Sense of Their Cancer Risks and Implications to Support Decision Making
Authors: Kohut Kelly , Morton Kate , Turner Lesley , Foster Rebecca , Bancroft Elizabeth K. , Esplen Mary Jane , Hanson Helen , Hurley Karen , Snape Katie ,   CanGene‐CanVar Patient Reference Panel,   International Lynch Decision Aid Stakeholder Panel, Eccles Diana , Foster Claire 
Published: September 2024

ABSTRACTBackgroundLynch syndrome carriers (‘carriers’) are presented with complex, emotionally laden choices regarding management of increased genetic cancer risks. Decision aids encourage active involvement in values‐based health decisions. This paper aimed to address the research question: How do Lynch syndrome carriers make sense of their chances of developing cancer, and what are the implications for providing support with decision making about genetic cancer risk management?MethodsAdult carriers were recruited through a genetics service or involvement with Lynch Syndrome UK. Semi‐structured interviews explored lived experiences of carriers' access to care with a focus on decision support. Themes were constructed using framework analysis. These were developed into a conceptual model with recommendations for codevelopment of improved information and support including a tailored decision aid to complement integrated healthcare.ResultsTwenty participants included 12 women and eight men, half with a history of cancer. Six overarching themes were: (1) finding balance with Lynch; (2) living ‘on higher alert’; (3) managing uncertainty: ‘I've thought about it a lot’; (4) burden of responsibility: ‘It's on me’; (5) access to joined‐up care and support: ‘There's something missing’; and (6) influence/pressure from others.ConclusionsThis qualitative interview study provided in‐depth insights from Lynch syndrome carriers about their lived experiences, informed by their values. Recommendations to empower carriers to make sense of genetic cancer risks and support decisions included accessible, trusted information, educated healthcare professionals, shared decision making, and joined‐up integrated care pathways complemented by tailored decision aids.
Clinical characteristics of Chinese children with EV‐D68‐associated pneumonia: A single‐center retrospective analysis
Authors: Xu Shasha , Tang Yu , Li Min , Zhang Lei , Su Yanyan , Wang Yanqiong , Liu Yuemei , Shen Yuelin 
Published: September 2024

AbstractBackgroundHuman enterovirus D68 (EV‐D68) has been associated with an increase in mild‐to‐severe pediatric respiratory diseases in western countries. However, the prevalence and clinical characteristics of EV‐D68‐associated pneumonia in China remain understudied.MethodsBetween January 2022 and January 2024, 28 patients with EV‐D68‐associated pneumonia were enrolled. We described the prevalence, demographic, and clinical characteristics of patients with EV‐D68‐associated pneumonia.ResultsAmong the 28 enrolled patients, the male‐to‐female ratio was 1.5:1, and the average age at onset was 4.6 ± 2.7 years. Four (14.3%) required intensive care support. Monoinfection occurred in 11 cases (39.3%), while coinfections were seen in 17 cases (60.7%). 82.1% of patients had a history of one or more atopic diseases. The primary symptoms of EV‐D68‐associated pneumonia included cough (100%), wheezing (53.6%), and fever (53.6%). Radiologically, patchy opacity was the predominant feature, observed in 72.7% of cases. No statistically significant differences were found in symptoms, laboratory tests, or imaging findings between the monoinfection and coinfection groups. Except for one case who developed quadriplegia sequelae, all patients had a favorable prognosis.ConclusionEV‐D68 is not a common pathogen for community‐acquired pneumonia in China. It mainly affects young children, particularly those with atopic constitution. The overall prognosis is favorable, although neurological complications are rare and may lead to severe sequelae. This study is the first investigation into the prevalence and clinical characteristics of EV‐D68‐associated pneumonia in China.
Evaluating the Use of Predicted Cushion Curves for Comparing the Performance of Some Sustainable Cushion Systems
Authors: Rouillard V. , Lamb M. J. 
Published: September 2024

ABSTRACTThis paper studies the cushion performance of a range of sustainable cushion systems and applies two methods to estimate cushion curves from limited cushion test data. The methods employed were previously developed to allow for (1) the conversion of cushion curves representing a material's performance for a given drop height and sample thickness to alternative (non‐measured) drop heights and sample thicknesses and (2) generating a complete cushion curve for a given thickness and drop height from a single acceleration (shock) measurement. The results include those generated for medium‐density polyethylene (MDP) closed‐cell foam for benchmarking of the materials and to aid in validating the approach. The results indicate that predicting cushion curves from single shock measurements is generally accurate for polymeric materials (MDP closed‐sell foam and HDPE inflated bag) but much less so for organic materials (sugarcane bagasse and perforated cardboard). Finally, all alternative cushioning materials and systems evaluated are shown to only be effective for very low static stresses. This finding demonstrates that much higher volumes are required when using the alternative materials to achieve the same cushioning effectiveness as MPD foam.
Separation of mycolic acid isomers by cyclic ion mobility‐mass spectrometry
Authors: de las Heras Prieto Hector , Cole Laura M. , Forbes Sarah , Palmer Martin , Schwartz‐Narbonne Rachel 
Published: September 2024

RationaleMycobacterial species contain high concentrations of mycolic acids in their cell wall. Mycobacteria can pose a threat to both human health and the environment. Mass spectrometry lipidomic characterization can identify bacterial species and suggest targets for microbiological interventions. Due to the complex structures of mycolic acids and the possibility of isobaric isomers, multiple levels of separation are required for complete characterization. In this study, cyclic ion mobility (cIM) mass spectrometry (MS) was used for the analysis, separation and fragmentation of mycolic acids isomers from the bacterial species Gordonia amarae and Mycobacterium bovis.MethodsMycolic acid isomers were interrogated from cultured G. amarae biomass and commercially available M. bovis mycolic acid extracts. These were infused into a cIM‐enabled quadrupole time‐of‐flight MS. Ions of interest were non‐simultaneously selected with the quadrupole and passed around the cyclic ion mobility device multiple times. Fragment ion analysis was then performed for the resolved isomers of the quadrupole‐selected ions.ResultsRepeated passes of the cIM device successfully resolved otherwise overlapping MA isomers, allowing isomer isolation and producing an ion‐specific post‐mobility fragmentation spectrum without isomeric interference.ConclusionsMycolic acids (MA) isomers from G. amarae and M. bovis were resolved, resulting in a high mobility resolution and low interference fragmentation analysis. These revealed varying patterns of MA isomers in the two species: G. amarae's most abundant ion of each set of MA has 1–2 conformations, while the MA + 2 m/z the most abundant ion of each set has 3–6 conformations. These were resolved after 70 passes of the cyclic device. M. bovis' most abundant ion of each keto‐MA set has 2 conformations, while the keto‐MA + 2 m/z has 1–2 conformations. These were resolved after 75 passes.
The Effect of Resistance Training on Markers of Cachexia in Patients with Heart Failure: A Systematic Review and Meta‐Analysis
Authors: Hanania Reina , Marina Nephtali , Cucchiaro Brittany , Slee Adrian 
Published: September 2024

ABSTRACTBackgroundCachexia is a metabolic syndrome characterised by muscle wasting that is highly prevalent in subjects with heart failure (HF) and negatively affects physical function, quality of life, morbidity and mortality. Resistance training has been recently incorporated into cardiac rehabilitation exercise programmes to increase muscle strength in patients with HF. This systematic review and meta‐analysis aim to assess the effects of resistance training on markers of cachexia in patients with HF.MethodsFour electronic databases (MEDLINE, Embase, CENTRAL and CINAHL) were searched to identify randomised controlled trials (RCTs) evaluating the effects of resistance training‐only programmes on published criteria for cachexia assessment including muscle strength, body composition (e.g. lean mass/muscle mass) or biochemical markers of cachexia (e.g. inflammatory markers) in patients with HF. Studies were selected based on pre‐specified inclusion and exclusion criteria, with a risk of bias assessment carried out. Meta‐analyses of muscle strength outcomes were completed using RevMan 5.4.1.ResultsNine studies were included in this review. Pooled analysis of one repetition‐maximum strength test of the lower [SMD 0.67 (95% Cl – 0.12, 1.22) p‐value = 0.02] and upper extremities [SMD 1.20 (95% Cl – 0.62, 1.79) p‐value <0.0001] showed a significant increase in muscle strength associated with resistance training, which are both important indicators of physical function. Resistance training did not increase muscle strength during rapid movements measured via peak torque at 60, 90 or 180°/s. There were no significant results recorded for changes in body composition and biochemical markers of cachexia. There were inconsistent findings for the effect of resistance training on quality of life. No studies reported findings on measures of anorexia or fatigue.ConclusionsThe findings of this review reveal the potential benefits of resistance training in preserving and enhancing muscle strength in patients with HF who are at risk of cardiac cachexia. Despite inconclusive results on body composition and quality of life, the inclusion of resistance training in cardiac rehabilitation guidelines has the potential to address issues of muscle weakness and frailty. Specific resistance training protocol recommendations to prevent or treat the development of cachexia cannot be made without the publication of more robust RCTs, specifically examining cachectic patients with heart failure with careful assessment of clinical outcomes of markers of cachexia.
Robotic Left Hepatectomy Using the Glissonean Approach and Saline‐Linked Bipolar Clamp‐Crush Technique
Authors: Kajiwara Masatoshi , Naito Shigetoshi , Sasaki Takahide , Nakashima Ryo , Hasegawa Suguru 
Published: September 2024

ABSTRACTBackgroundWe have previously reported a saline‐linked bipolar clamp‐crush technique as a novel robotic liver resection method. Herein, we present the surgical techniques and outcomes of robotic left hepatectomy using the Glissonean approach and our liver transection technique.MethodsThe key procedures included the following: (1) encircling the left Glissonean pedicle using the Tip‐Up fenestrated grasper, (2) dissecting the liver parenchyma using the saline‐linked bipolar clamp‐crush technique, (3) moving the endoscope one trocar to the right to facilitate visualisation of the liver transection plane, and (4) stapling the left pedicle and left hepatic vein. Seven robotic left hepatectomies were performed.ResultsThe median operative time and estimated blood loss were 395 min and 50 mL, respectively. The median length of postoperative hospital stay was 9 days. Pneumothorax was the only severe postoperative complication.ConclusionsRobotics left hepatectomy using the Glissonean approach and the saline‐linked bipolar clamp‐crush technique appears safe and feasible.
Compound heterozygous KCTD19 variants in a man with isolated nonobstructive azoospermia
Authors: Muranishi Yuki , Katoh‐Fukui Yuko , Hattori Atsushi , Kobori Yoshitomo , Osaka Akiyoshi , Okada Hiroshi , Iwahata Toshiyuki , Kon Masafumi , Shinohara Nobuo , Fukami Maki 
Published: September 2024

AbstractCaseA 40‐year‐old Japanese man with nonobstructive azoospermia (NOA) was found to carry rare variants in KCTD19, a newly identified causative gene for spermatogenic failure. This patient was identified through mutation screening of KCTD19 in 97 men with etiology‐unknown isolated NOA.OutcomeThe patient had two heterozygous variants in KCTD19 that affect consensus sequences of splice‐donor sites [c.300+2T>A and c.2667C>T (p.E889E)]. Both variants were predicted to cause exon skipping. Long‐read sequencing confirmed the compound heterozygosity of the variants. The patient exhibited small testes and a mildly elevated level of follicle‐stimulating hormone but no other phenotypic abnormalities. Testicular histology showed borderline findings between spermatocyte maturation arrest and severe hypospermatogenesis.ConclusionThese results provide evidence that biallelic loss‐of‐function variants of KCTD19 represent rare causes of isolated NOA.
Contingent Contradictions and the (Il)Logics of Adolescence: Examining How Undergraduates in an LGBTQ+ Young Adult Literature Course Read Queer Youth
Authors: Smith Kyle P. , Wargo Jon M. 
Published: September 2024

AbstractThis article explores how undergraduate students enrolled in a postsecondary course centering LGBTQ+ young adult literature came to discursively construct notions of queer youth. Braiding postdevelopmental and poststructural theories of childhood with queer theory, we interrogated how what we name as the (il)logics of adolescence shaped who and what queer youth, as a construct, was and could be for participants. Reading across classroom artifacts and student talk about texts, our findings highlight the shifting and multiple (il)logics offered by students as they attempted to unsettle understandings of queer youth in conjunction with course novels. In particular, we examine how two constitutive theories—homonormativity and chrononormativity—generated both contingent and contradictory moments wherein the subject of the queer child was both regulated and liberated by participants. Offering implications that expand understandings in both the reading and teaching of queer young adult literature, the study closes by discussing this particularly contentious moment, noting possibilities in how LGBTQ+ adolescents can and cannot be rendered and understood through stories of youth.
Experimental and Quantum Chemical Studies of a Green Corrosion Inhibitor for Mild Steel in Acidic Chloride Solution
Authors: Zou Jiawei , Ai Wenying , Zhao Qifeng , Liu Kexin , Zhang Wenjing , Liu Yuan , Li Ping , Li Pengyu , Cui Siwen , Cao Jian , Jiao Mingli , Li Xia 
Published: September 2024

AbstractA green corrosion inhibitor was prepared from the bio‐based platform compound 5‐hydroxymethylfurfural through a green synthetic route, which avoid the use of toxic reagent. The inhibition performance and mechanism of this compound for the corrosion of mild steel in 0.1 M HCl was investigated by using the weight loss experiments, polarization measurements, EIS measurements and quantum chemical calculations. The corrosion inhibition efficiency by weight loss measurement (ηWLM%) of this inhibitor can reach up to 90.3 % at 303 K with 1.2 mM concentration. Moreover, the electrochemical experiments revealed that this corrosion inhibitor acts as a mixed‐type inhibitor. Thermodynamic studies gave the values of the standard Gibbs free energy
, fall within the range of −20 kJ/mol to −40 kJ/mol, suggested the adsorption of this compound is a spontaneous process involving both physisorption and chemisorption. In addition, quantum chemical calculations were conducted to further validate the formation of an effective absorption layer by this inhibitor on metal surfaces, which showed that the electron density iso‐surfaces of HOMO was mainly distributed on chloride ions, while LUMO tended to be distributed on furan rings and aldehyde groups. Besides, the other quantum chemical parameters of this inhibitor were also calculated to explore the molecular activity, such as, the molecular volume (ν, 333.105 Å), global hardness (η, 4.706 eV), global softness (σ, 0.2125 eV), electronegativity (χ, 4.93 eV), dipolemoment (μ, 13.1429 D) and vertical ionization energy (VIE, 7.2646 eV).