bluuebunny/crossref_metadata_2025_split huggingface dataset:
Less frequent radiological exams to avoid futile response assessments from 177-LuDOTATE therapy for patients with advanced neuroendocrine tumors
Authors: Marques Carolina C , Brito Angelo B , Lima Eduardo N , Donadio Mauro D , Riechelmann Rachel P 
Published: September 2024

Background
177-LuDOTATE is an effective but expensive treatment for neuroendocrine tumors (NETs). Reducing treatment-related costs, such as the number of images, could improve access to 177-LuDOTATE. We evaluated early radiological tumor progression and prognostic factors in patients with NETs treated with 177-LuDOTATE.

Methods
We retrospectively included all patients with NETs who received at least one cycle of 177-LuDOTATE. The primary endpoint was the rate of early radiological progression between cycles 2 and 3 (in 10–16 weeks). Secondary endpoints were progression-free survival (PFS) and overall survival (OS) according to prognostic factors (tumor grade, primary site, functioning syndrome, 177-LuDOTATE treatment line) in Cox proportional hazards models.

Results
The median number of 177-LuDOTATE cycles was 3 (range 1–6) among 59 patients included. Ten (17%) patients had early progression. Among 14 patients who received ≤2 cycles of 177-LuDOTATE, ten (72%) stopped treatment due to disease progression, with five patients having a G2 (ki67: 5–25%) and 4, a G3 (ki67: 25–90%) NET. In the Cox multivariable analysis, higher grade (G2 or G3 vs G1) were significantly associated with inferior PFS and OS. The median PFS of G1, G2 and G3 NET patients were: 34.1, 11.7 and 6.1 months (P = 0.015), respectively.

Conclusions
It is feasible to perform imaging tests after 177-LuDOTATE completion for patients with indolent NETs with the intent to avoid futile assessments. For patients with more aggressive diseases, such as G3 NETs and G2 tumors with high tumor burden, we advise to perform more frequent images during 177-LuDOTATE therapy.
CHRONOLOGIES OF GAS COMPONENTS IN DECIDUOUS TREE RINGS
Authors: АГЕЕВ Б.Г. , САПОЖНИКОВА В.А. , ГРУЗДЕВ А.Н. , САВЧУК Д.А. 
Published: September 2024

Проведены измерения газов, десорбированных вакуумным методом из колец спилов лиственных деревьев с использованием оптико-акустического газоанализатора с перестраиваемым СО2-лазером. Получены хронологии остаточных газов СО2 и (СО2 + Н2О) некоторых лиственных деревьев, произрастающих в районе г. Томска (Западная Сибирь). Хронологии характеризуются хорошо выраженными 2-4-летними циклами. Найдена корреляция содержания газов с летними температурами и осадками. Полагаем, что погодичное распределение остаточных газов в спилах отражает картину поступления газов из стволов лиственных деревьев в атмосферу.
Gases desorbed by the vacuum method from the tree rings of discs of deciduous trees are measured. The content of residual gases vacuum-desorbed from tree rings is analyzed with an opto-acoustic gas analyzer with a tunable CO2 laser. The chronologies of residual CO2 and (CO2 + H2O) of some deciduous trees growing near the city of Tomsk (West Siberia) have been derived. All the chronologies are cyclic with pronounced 2-4-year cycles. A correlation was found between the content of gases and summer temperatures and precipitation. We believe that the annual distribution of residual gases in the discs reflects the pattern of annual release of the gases from the stems of the deciduous trees into the atmosphere.
ESTIMATES OF CO2 FLUX INTO THE FOREST ECOSYSTEM BASED ON THE RESULTS OF GROUND-BASED HYPERSPECTRAL SOUNDING OF THE ATMOSPHERE AND AN ARTIFICIAL NEURAL NETWORK MODEL
Authors: РОЗАНОВ А.П. , ЗАДВОРНЫХ И.В. , ГРИБАНОВ К.Г. , ЗАХАРОВ В.И. 
Published: September 2024

Приведены результаты гиперспектрального зондирования атмосферы на Уральской атмосферной станции в пос. Коуровка Свердловской обл. за период 2012-2022 гг. Показано, что средняя скорость роста СО2 в атмосфере данного региона составляет ~ 2,5 ppm/год. Двумя независимыми методами оценено количество поглощаемого из атмосферы углекислого газа лесной экосистемой на единицу площади за вегетационный период (апрель - сентябрь) в окрестности карбонового полигона в Коуровке. Первый метод основан на использовании данных о содержании СО2 в атмосферном столбе, полученных при зондировании атмосферы наземным ИК-Фурье-спектрометром высокого разрешения, а во втором методе применяется оригинальная нейросетевая модель, на вход которой подаются данные спектральных каналов спутникового сенсора MODIS. Полученные результаты демонстрируют хорошее согласие: количество СО2, поглощенного лесной экосистемой из атмосферы, в окрестности карбонового полигона за вегетационный период 2022 г. составляет ~ 1,5 т/га (первый метод) и ~ 1,3 т/га (второй метод).
The results of hyperspectral sounding of the atmosphere at the Ural Atmospheric Station in Kourovka from 2012-2022 are presented. It is shown that the average rate of CO2 growth in the atmosphere of this region is about 2.5 ppm per year. The amount of carbon dioxide absorbed from the atmosphere by the forest ecosystem per unit area during the growing season (April-September) in the vicinity of the carbon landfill in Kourovka is estimated using two independent methods. One method is based on the data on the CO2 total column obtained from sounding the atmosphere with a ground-based high-resolution infrared Fourier spectrometer. The second method is based on the use of an artificial neural network with data from spectral channels of the MODIS satellite sensor as injnit. The results obtained by both methods demonstrate good agreement. The estimates made show that the amount of CO2 absorbed from the atmosphere by the forest ecosystem in the vicinity of the carbon landfill site during the growing season of 2022 is about 1.5 t/ha (the first method) and about 1.3 t/ha (the second method).
CARBON DIOXIDE EMISSIONS FROM RIVERS IN WESTERN SIBERIA
Authors: АРШИНОВ М.Ю. , БЕЛАН Б.Д. , ДАВЫДОВ Д.К. , СИМОНЕНКОВ Д.В. , ФОФОНОВ А.В. 
Published: September 2024

Одним из возможных источников поступления углекислого газа в атмосферу могут быть речные экосистемы. Приводятся результаты измерения потоков СО2 с поверхности нескольких рек и озер Томской обл. Показано, что в период экспериментов средние потоки углекислого газа составляли для р. Оби 143,7 ± 21,7 (13-14.08.2023 г.), 53,3 ± 21,2 (19.08.2023 г.) и 80,4 ± 59,9 мгС × м-2 × ч-1 (20.08.2023 г.); для р. Кеть - 66,1 ± 17,3; болотного озера Карасевое - 33,3 ± 17,3; р. Суйга 50,2 ± 23,0; р. Икса - 81,9 ± 11,5 мгС × м-2 × ч-1. Их величина существенно зависела не только от объекта исследования, но и от гидрометеорологических условий.
One of the possible sources of carbon dioxide entering the atmosphere may be river ecosystems. The paper presents the results of measuring CO2 fluxes from the surface of a number of rivers and lakes in the Tomsk region. It is shown that during the period of experiments the average carbon dioxide flows for the Ob River were 143.7 ± 21.7 (August 13-14, 2023), 53.3 ± 21.2 (August 19), and 80.4 ± 59.9 mgC × m-2 × hour-1 (August 20), respectively. On the river Ket: 66.1 ± 17.3, on the swamp lake Karasevoye 33.3 ± 17.3, on the Suiga River 50.2 ± 23.0, and the Iksa River 81.9 ± 11.5 mgC × m-2 × hour-1. Their magnitudes depended significantly not only on the object of study, but also on hydrometeorological conditions.
AUTOMATED SYSTEM FOR THE ANALYSIS OF FLUORESCENT CHARACTERISTICS OF MICROALGAE MONOCULTURES
Authors: ПОПИК А.Ю. , ГАМАЮНОВ Е.Л. , ВОЗНЕСЕНСКИЙ С.С. 
Published: September 2024

Методы лазерно-индуцированной флуоресценции и их использование в средствах мониторинга позволяют решать ряд ключевых задач по обнаружению цветений водорослей. Разработана автоматизированная система обработки и анализа больших массивов флуоресцентных спектральных характеристик культур микроводорослей. Она позволяет определять доминирующие в акватории культуры на уровне рода и оценивать возможность возникновения их цветения. С помощью этой системы можно формировать каталоги эталонных оптических характеристик культур микроводорослей и реализовывать интерактивные алгоритмы обнаружения опасных видов микроводорослей.
Methods of laser-induced fluorescence and their use in monitoring tools allow solving a number of key problems in the detection of algal blooms. The automated system developed by us makes it possible to process and analyze huge amount of fluorescent spectral characteristics of microalgae monocultures, to determine the dominant monocultures in the water area at the level of genus, and to estimate a possibility of their blooming. In addition, the system makes it possible to catalog reference optical characteristics of microalgae monocultures and to implement interactive algorithms for detecting dangerous microalgae species.
Methodology study for determining the half-value layer using the Monte Carlo code PHITS
Authors: Soares Ronald , Lacerda Marco Aurélio 
Published: September 2024

For most purposes, the quality of a beam can be specified in terms of the half-value layer (HVL), which is the thickness of material required to reduce the air kerma to half, at one meter from the source, from a unidirectional beam of infinitesimal width. Just like many other radiological quantities of interest, the HVL can be estimated via simulations employing the Monte Carlo Method (MCM). Among the variety of MCM based codes available, the Particles and Heavy Ions Transport Code System (PHITS) was the one adopted in this study. Primarily, simulations were conducted to determine the X-ray spectra resulting from the interaction of electron beams with different energies with a tungsten anode. Each of these spectra was then defined as a probability distribution for the photon source energies in a second round of simulations, where it was possible to estimate the X-ray beam qualities as specified by the reference literature. At this stage, it was possible to estimate the mean energy of the beam and the conversion coefficient for air kerma per unit fluence for each of the qualities. The results obtained in this phase were used to define the sources for other groups of simulations, where the air kerma was quantified for each source configuration, for different thicknesses of an aluminum metallic attenuator, which was also done with spectra for the same X-ray beam qualities obtained from a reference catalog. Curve fitting on the scatter of kerma points as a function of attenuation allowed the estimation of the HVL. The results obtained are consistent with the values described in the literature and demonstrate the efficiency of the developed methodology, as well as the use of the code in the evaluated energy range for X-rays.
Analisis Budi Daya Lobster Berkelanjutan di Lombok, Nusa Tenggara Barat
Authors: Rohmanurcaesari Abdari , Anggraini Eva , Buhari Nurliah 
Published: September 2024

ujuan penelitian ini adalah untuk melihat kelayakan usaha dan merumuskan pengelolaan usaha budi daya lobster yang berkelanjutan di Lombok, Nusa Tenggara Barat dengan melihat dari dimensi ekologi, ekonomi, kelembagaan, sosial dan teknologi. Kelayakan dihitung dengan analisis biaya manfaat dan keberlanjutan usaha dilihat dengan analisis RAPFISH (Rapid Appraisal for Fisheries). Lokasi penelitian dilakukan di kecamatan Jerowaru. Penentuan responden dilakukan menggunakan purposive sampling. Jumlah responden ditentukan dengan rumus Slovin didapat hasil 92 pembudidaya, akan tetapi untuk mengantisipasi outlier data maka diambil 99 pembudidaya. Berdasarkan data yang telah diolah memiliki hasil bahwa pada kapasitas usaha 8 lubang, 12 lubang dan 16 lubang layak, sedangkan pada kapasitas usaha 4 lubang tidak layak. Hasil indeks keberlanjutan menunjukan bahwa dimensi ekologi, dimensi ekonomi, dan dimensi sosial adalah cukup berkelanjutan, dimensi teknologi adalah kurang berkelanjutan, dan dimensi kelembagaan adalah tidak berkelanjutan. Title: Sustainable Management of Lobster Farming in Lombok, West Nusa TenggaraThe purpose of this study is to look at business feasibility and formulate sustainable management of lobster farming in Lombok, West Nusa Tenggara by looking at the ecological, economic, institutional, social and technological dimensions. Feasibility is calculated by benefit cost analysis and business sustainability is seen by RAPFISH (Rapid Appraisal for Fisheries) analysis. The research location was in Jerowaru sub-district. Determination of respondents was done using purposive sampling. The number of respondents was determined by the Slovin formula, resulting in 92 cultivators, but to anticipate data outliers, 99 cultivators were taken. Based on the data that has been processed, the results show that the business capacity of 8 holes, 12 holes and 16 holes is feasible, while the business capacity of 4 holes is not feasible. The results of the sustainability index show that the ecological dimension, economic dimension, and social dimension are quite sustainable, the technological dimension is less sustainable, and the institutional dimension is unsustainable.
Dampak Kebijakan Pelarangan Cantrang di Kecamatan Paciran, Kabupaten Lamongan, Provinsi Jawa Timur
Authors: Syamsuddin Azrin , Fauzi Akhmad , Fahrudin Achmad , Anggraini Eva 
Published: September 2024

Pelarangan operasi alat tangkap cantrang (ATC) melalui Permen KP No.2/Permen-KP/2015 yang kemudian diperbaiki dengan Permen KP No.71/Permen-KP/2016 berpengaruh terhadap kegiatan perikanan di Kecamatan Paciran, Kabupaten Lamongan, Jawa Timur. Penelitian ini bertujuan untuk menganalisis dampak ekonomi dan sosial bagi pelaku usaha yang bergantung pada komoditas ikan tangkapan ATC. Penelitian dilaksanakan pada Maret—April 2019 di tiga desa nelayan di kecamatan tersebut. Pengumpulan data dilakukan melalui wawancara terhadap pelaku usaha perikanan yang memanfaatkan alat tangkap cantrang. Penelitian ini merupakan penelitian deskriptif kualitatif yang memberikan gambaran kondisi ekonomi dan sosial pelaku usaha di lapangan. Analisis pada penelitian ini dilakukan dengan menggunakan pendekatan mactor, smic-prob, dan multipol. Hasil analisis menunjukkan bahwa kebijakan pelarangan ATC berpengaruh signifikan terhadap pelaku usaha perikanan, khususnya nelayan penangkap ikan dan pelaku usaha industri hilirnya. Oleh karena itu, strategi skenario pembangunan ke depan adalah perlunya adaptasi dengan memodifikasi alat tangkap cantrang, koordinasi seluruh aktor di lapangan dalam implementasi adaptasi, penggantian alat tangkap dengan melibatkan aparat keamanan, dan pengalihan mata pencaharian nelayan dari penangkapan ikan ke pembudidayaan ikan.Title: The Impacts of Cantrang Prohibition Policy in Paciran Sub-district, Lamongan Regency, East Java Province The prohibition on the operation of cantrang through the Ministerial Decree No. 2/Permen-KP/2015 which was later corrected by the Ministerial Decree No. 71/Permen-KP/2016 has an effect on fisheries activities in Paciran District, Lamongan Regency, East Java. This study aims to analyze the economic and social impacts on business actors who depend on cantrang caught fish commodities. The research was conducted in March—April 2019 in three fishing villages in the sub-district. Data was collected through interviews with fisheries business actors who used cantrang. This research is a qualitative descriptive study that provides an overview of the economic and social conditions of business actors in the field. The analysis in this study was carried out using the Mactor, Smic-Prob, and Multipol approaches. The results of the analysis show that the cantrang prohibition policy has a significant effect on fisheries business actors, especially fishers and their downstream industry business actors. Therefore, the future development scenario strategy is adaptation toward this policy by modifying cantrang fishing gear, coordinating of all actors in implementing adaptation, replacing fishing gear by involving security forces, and diverting fishers livelihoods from fishing to fish cultivation.
Logistics Cost Analysis of Catfish in Special Region of Yogyakarta, Indonesia: Internal and External of Logistics Component Costing Systems
Authors: Sylvia Teny , Widodo Kuncoro Harto , Ismoyowati Dyah 
Published: September 2024

Catfish are the most popular cultivated fish in special region of yogyakarta in special region of yogyakarta especially Sleman, Kulon Progo, and Bantul District. These products are categorized as high perishable product so need a special handling to keep the quality from fish farmers to the customers. The aims of this study are to identify and calculate the logistics cost component that needed to keep the quality along the supply chain of catfish. There are three types of data collection methods used, namely observation, in- depth interview, and literature review. The analysis includes descriptive analysis, logistics cost components using ABC, and cost charging systems. Furthermore, it can be known the proportion of each logistics cost component of catfish. This study shows that there are six component of catfish logistics cost, i.e. procurement, material handling, transportation, maintenance, inventory, and customer communication. It also shows that the highest logistics cost component averaged proportion is, 76.421%, material handling.
Analisis Illegal Fishing Di Perairan Aceh
Authors: Afriandi Fadli , Ariyadi Fachriza , Abdillah Ligar , Lestari Yeni Sri 
Published: September 2024

Tulisan ini merupakan kajian politik keamanan nontradisional yang berfokus kepada illegal fishing. Illegal fishing merupakan bentuk ancaman yang dapat merusak hubungan antar negara, lingkungan hidup, dan berdampak terhadap keamanan manusia. Tulisan ini berupaya menganalisis mengapa kasus illegal fishing oleh kapal ikan asing dan kapal ikan Indonesia di Provinsi Aceh sering kali terjadi. Kasus illegal fishing yang terjadi di Aceh dianalisis menggunakan pendekatan keamanan nontradisional dengan menggunakan Teori Sea Power Mahan. Metode penelitian yang digunakan adalah metode kualitatif dengan teknik pengumpulan data melalui wawancara mendalam dan studi pustaka. Penelitian dilaksanakan dari bulan Agustus hingga September 2022. Hasil dari penelitian ini adalah kasus illegal fishing terjadi disebabkan oleh faktor wilayah, masyarakat, dan pemerintah. Faktor wilayah seperti jauhnya Aceh dari pusat pemerintahan dan berada di wilayah perbatasan. Faktor dari masyarakat misalnya sedikitnya jumlah nelayan, adanya tradisi larangan melaut, dan masih menggunakan alat tangkap yang dilarang. Terakhir faktor pemerintah adalah rendahnya pengawasan, dan kebijakan yang tidak ramah illegal fishing. Title: Analysis Illegal Fishing in The Aceh WatersThis paper studies non-traditional security politics that focus on illegal fishing. Illegal fishing is a form of threat that can damage relations between countries and the environment and have an impact on human security. This paper analyses why illegal fishing by foreign and Indonesian fishing boats often occurs in Aceh Province. Cases of illegal fishing that occurred in Aceh were analyzed using a nontraditional security approach using Mahan’s Sea Power Theory. The research method used is qualitative, with data collection techniques through in-depth interviews and literature study. The research was conducted from August to September 2022. The results of this study are cases of illegal fishing that occur due to regional, community, and government factors. Regional factors include Aceh’s distance from the central government, and being in a border area. Aspects from the community, for example, the small number of fishermen, the tradition of prohibiting going to sea, and still using prohibited fishing gear. Finally, the government factor is the low level of supervision and policies that could be more friendly to illegal fishing.
Analisis Faktor-Faktor yang Memengaruhi Buoyancy PNBP Sektor Perikanan Subsektor SDA
Authors: Rahmawati Nur Alifah , Purwanti Evi Yulia 
Published: September 2024

Indonesia memiliki wilayah perairan yang luas dengan sumber daya perikanan melimpah yang dapat meningkatkan penerimaan negara khususnya dari penerimaan bukan pajak subsektor sumber daya alam (SDA). Dengan daya apung PNBP, responsivitas PNBP sektor perikanan subsektor SDA terhadap perubahan PDB dapat diukur. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi daya apung PNBP sektor perikanan subsektor SDA pada tahun 2002—2021. Penelitian ini menggunakan data sekunder yang diperoleh dari Kementerian Keuangan, Kementerian Kelautan dan Perikanan, dan BPS dengan metode analisis regresi Error Correction Model (ECM). Hasil penelitian menunjukkan dalam jangka pendek, nilai produksi perikanan dan reformasi PNBP sektor perikanan berpengaruh positif dan signifikan, illegal fishing berpengaruh negatif dan signifikan. Akan tetapi realisasi belanja KKP tidak berpengaruh signifikan terhadap daya apung PNBP sektor perikanan subsektor SDA. Dalam jangka panjang nilai produksi perikanan, realisasi belanja KKP, illegal fishing, dan reformasi PNBP sektor perikanan tidak berpengaruh signifikan terhadap daya apung PNBP sektor perikanan subsektor SDA. Sebagai rekomendasi, perlu adanya kebijakan yang terukur dan konsisten dilakukan dalam mendukung optimalisasi pemanfaatan SDA perikanan sebagai sumber penerimaan negara.Title: Analysis of Factors Affecting Buoyancy of PNBP in the Fisheries Sector of Natural Resources SubsectorIndonesia has vast territorial waters with abundant fishery resources which can increase state revenues, especially from PNBP of the natural resources. With the buoyancy of PNBP, the responsiveness of PNBP in the fisheries sector of natural resources can be measured against changes in GDP. This research aims to analyze the buoyancy of PNBP in the fisheries sector of natural resources from 2002 – 2021. This research used secondary data obtained from the Ministry of Finance, the Ministry of Marine Affairs and Fisheries, and the Central Statistics Agency, using the Error Correction Model (ECM) regression analysis method. The results showed that in the short term, the fishery production value and PNBP reform in the fisheries sector have a positive and significant effect, and illegal fishing has a negative and significant effect. However, the realization of KKP spending does not have a significant effect on the buoyancy of PNBP in the fisheries sector of the natural resources subsector. In the long term, the fishery production value, the realization of KKP spending, illegal fishing, and PNBP reform in the fisheries sector do not significantly affect the buoyancy of PNBP in the fisheries sector of the natural resources subsector. As a recommendation, there needs to be a measurable and consistent policy carried out in supporting the optimization of the use of fishery resources as a source of state revenue.