bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association between frequency of blood donation and the occurrence of low birthweight, preterm delivery, and stillbirth: a retrospective cohort study
Authors: Germain Marc , Delage Gilles , Robillard Pierre , Katz Louis M. , Grégoire Yves 
Published: August 2016

BACKGROUNDWomen who donate blood on a regular basis are at high risk of becoming iron depleted. Iron deficiency anemia has been shown to increase the risk of low birthweight and possibly preterm birth. Therefore, there is a concern that regular blood donation by female donors might adversely impact the well‐being of their offspring. This retrospective cohort study examined the association between blood donation and the occurrence of adverse pregnancy outcomes.STUDY DESIGN AND METHODSThe study sample included 18,483 female blood donors in their childbearing years (age 18 to 45 years) who delivered during the period 2001 to 2011 in the province of Québec (Canada). The occurrence of low birthweight (<2500 g), preterm delivery (<37 weeks of gestation), and stillbirth was ascertained by linking the donor information with provincial birth and stillbirth registries.RESULTSThere was no association between the frequency of donation in the 2‐year period before pregnancy and adverse pregnancy outcomes; compared to women who did not donate during that period, those who donated three or more donations (mean, 3.9 donations) had a relative risk of 0.83 (95% confidence interval [CI], 0.65‐1.06) for low birthweight, 0.91 (95% CI, 0.75‐1.11) for preterm birth, and 0.62 (95% CI, 0.18‐2.12) for stillbirth. These associations remained unchanged after adjusting for baseline characteristics.CONCLUSIONWomen who donate blood on a regular but moderate basis do not appear to be at higher risk of adverse pregnancy outcomes. These findings, while reassuring, will need to be replicated in different settings.
Fixed Export Costs and Trade Patterns: The Case of China
Authors: Gao Yu , He Yin , Yin Xiaopeng 
Published: August 2016

AbstractCurrent research on heterogeneous firms does not include firms' choices on trade patterns. This is an important issue in developing countries. The growth in the number of low‐productivity processing firms in developing countries needs further study to show how these firms survive and prosper. In this study, we adopt the idea in Castro, Li, Maskus and Xie that fixed trade costs should be a co‐determinant of a firm's export decisions and it is a substitute for productivity. We use firm‐level data for China, for the period 2000–2006, to show that fixed export costs play a key role in firms' trade pattern decisions. More specifically, firms with low productivity and low fixed trade costs have a significantly higher probability to choose the processing trade pattern. Although the processing trade is often criticised for its low productivity and value added, it has natural advantages in its savings on fixed export costs. Therefore, the exporting firm is able to survive, prosper and contribute to growth in developing regions.
Registration of human skull computed tomography data to an ultrasound treatment space using a sparse high frequency ultrasound hemispherical array
Authors: O'Reilly Meaghan A. , Jones Ryan M. , Birman Gabriel , Hynynen Kullervo 
Published: August 2016

Purpose:Transcranial focused ultrasound (FUS) shows great promise for a range of therapeutic applications in the brain. Current clinical investigations rely on the use of magnetic resonance imaging (MRI) to monitor treatments and for the registration of preoperative computed tomography (CT)‐data to the MR images at the time of treatment to correct the sound aberrations caused by the skull. For some applications, MRI is not an appropriate choice for therapy monitoring and its cost may limit the accessibility of these treatments. An alternative approach, using high frequency ultrasound measurements to localize the skull surface and register CT data to the ultrasound treatment space, for the purposes of skull‐related phase aberration correction and treatment targeting, has been developed.Methods:A prototype high frequency, hemispherical sparse array was fabricated. Pulse‐echo measurements of the surface of five ex vivo human skulls were made, and the CT datasets of each skull were obtained. The acoustic data were used to rigidly register the CT‐derived skull surface to the treatment space. The ultrasound‐based registrations of the CT datasets were compared to the gold‐standard landmark‐based registrations.Results:The results show on an average sub‐millimeter (0.9 ± 0.2 mm) displacement and subdegree (0.8° ± 0.4°) rotation registration errors. Numerical simulations predict that registration errors on this scale will result in a mean targeting error of 1.0 ± 0.2 mm and reduction in focal pressure of 1.0% ± 0.6% when targeting a midbrain structure (e.g., hippocampus) using a commercially available low‐frequency brain prototype device (InSightec, 230 kHz brain system).Conclusions:If combined with ultrasound‐based treatment monitoring techniques, this registration method could allow for the development of a low‐cost transcranial FUS treatment platform to make this technology more widely available.
Should regional ventilation function be considered during radiation treatment planning to prevent radiation‐induced complications?
Authors: Lan Fujun , Jeudy Jean , Senan Suresh , van Sornsen de Koste J. R. , D'Souza Warren , Tseng Huan‐Hsin , Zhou Jinghao , Zhang Hao 
Published: August 2016

Purpose:To investigate the incorporation of pretherapy regional ventilation function in predicting radiation fibrosis (RF) in stage III nonsmall cell lung cancer (NSCLC) patients treated with concurrent thoracic chemoradiotherapy.Methods:Thirty‐seven patients with stage III NSCLC were retrospectively studied. Patients received one cycle of cisplatin–gemcitabine, followed by two to three cycles of cisplatin–etoposide concurrently with involved‐field thoracic radiotherapy (46–66 Gy; 2 Gy/fraction). Pretherapy regional ventilation images of the lung were derived from 4D computed tomography via a density change–based algorithm with mass correction. In addition to the conventional dose–volume metrics (V20, V30, V40, and mean lung dose), dose–function metrics (fV20, fV30, fV40, and functional mean lung dose) were generated by combining regional ventilation and radiation dose. A new class of metrics was derived and referred to as dose–subvolume metrics (sV20, sV30, sV40, and subvolume mean lung dose); these were defined as the conventional dose–volume metrics computed on the functional lung. Area under the receiver operating characteristic curve (AUC) values and logistic regression analyses were used to evaluate these metrics in predicting hallmark characteristics of RF (lung consolidation, volume loss, and airway dilation).Results:AUC values for the dose–volume metrics in predicting lung consolidation, volume loss, and airway dilation were 0.65–0.69, 0.57–0.70, and 0.69–0.76, respectively. The respective ranges for dose–function metrics were 0.63–0.66, 0.61–0.71, and 0.72–0.80 and for dose–subvolume metrics were 0.50–0.65, 0.65–0.75, and 0.73–0.85. Using an AUC value = 0.70 as cutoff value suggested that at least one of each type of metrics (dose–volume, dose–function, dose–subvolume) was predictive for volume loss and airway dilation, whereas lung consolidation cannot be accurately predicted by any of the metrics. Logistic regression analyses showed that dose–function and dose–subvolume metrics were significant (P values ≤ 0.02) in predicting volume airway dilation. Likelihood ratio test showed that when combining dose–function and/or dose–subvolume metrics with dose–volume metrics, the achieved improvements of prediction accuracy on volume loss and airway dilation were significant (P values ≤ 0.04).Conclusions:The authors’ results demonstrated that the inclusion of regional ventilation function improved accuracy in predicting RF. In particular, dose–subvolume metrics provided a promising method for preventing radiation‐induced pulmonary complications.
Genome Sequence of
Gordonia
Phage Emalyn
Authors: Pope Welkin H. , Guido Madeline J. , Iyengar Pragnya , Nigra Jonathan T. , Serbin Matthew B. , Kasturiarachi Naomi S. , Pressimone Catherine A. , Schiebel Johnathon G. , Furbee Emily C. , Grubb Sarah R. , Warner Marcie H. , Montgomery Matthew T. , Garlena Rebecca A. , Russell Daniel A. , Jacobs-Sera Deborah , Hatfull Graham F. 
Published: August 2016

ABSTRACT

Emalyn is a newly isolated bacteriophage of
Gordonia terrae
3612 and has a double-stranded DNA genome 43,982 bp long with 67 predicted protein-encoding genes, 32 of which we can assign putative functions. Emalyn has a prolate capsid and has extensive nucleotide similarity with several previously sequenced phages.
Complete Genome Sequence of
Escherichia coli
ER1821R, a Laboratory K-12 Derivative Engineered To Be Deficient in All Methylcytosine and Methyladenine Restriction Systems
Authors: Jobling Michael G. , Raleigh Elisabeth A. , Frank Daniel N. 
Published: August 2016

ABSTRACT

We present here the complete genomic sequence of a rifampin-resistant derivative of the
Escherichia coli
K-12 laboratory strain ER1821, engineered to be deficient in all known restriction systems, making it suitable for generating unbiased libraries from organisms with non-K-12 methylation patterns. The ER1821R genome is most closely related to that of DH1, another popular cloning strain (both derived from MM294), but is deleted for the
e14
prophage (McrA
-
) and the immigration control (McrBC
-
EcoKI R
-
M
-
Mrr
-
) loci.
Draft Genome Sequences of
Citrobacter freundii
Strains CF04 and A41 Isolated from Moribund, Septicemic Giant Gourami (
Osphronemus goramy)
in Sri Lanka
Authors: Honein Karim , Jagoda S. S. S. De S. , Arulkanthan Appudurai , Ushio Hideki , Asakawa Shuichi 
Published: August 2016

ABSTRACT

Citrobacter freundii
is a Gram-negative opportunistic pathogen associated with many infectious conditions including septicemia in humans and animals. Here, we announce the draft genome sequences of two multidrug-resistant
C. freundii
strains (CF04 and A41) isolated from septicemic giant gourami (
Osphronemus goramy
) collected from aquaria in Sri Lanka.
Draft Genome Sequence of
Anoxybacillus suryakundensis
Strain JS1
T
(DSM 27374
T
) Isolated from a Hot Spring in Jharkhand, India
Authors: Deep Kamal , Poddar Abhijit , Whitman William B. , Das Subrata K. 
Published: August 2016

ABSTRACT

Anoxybacillus suryakundensis
strain JS1
T
, a facultative anaerobic, moderately thermophilic, alkalitolerant bacterium, was isolated from a hot spring. The estimated genome is 2.6 Mb and encodes 2,668 proteins.
Draft Genome Sequence of
Gulbenkiania indica
Strain HT27
T
(DSM 17901
T
) Isolated from a Sulfur Spring in India
Authors: Badhai Jhasketan , Narayan Kunwar Digvijay , Whitman William B. , Das Subrata K. 
Published: August 2016

ABSTRACT

Gulbenkiania indica
strain HT27
T
was isolated from a sulfur spring. Here, we report the first representative draft genome sequence of a type strain of the genus
Gulbenkiania
. The estimated genome is 2.8 Mb, with 2,713 protein-coding sequences.
Draft Genome Sequence of
Idiomarina woesei
Strain W11
T
(DSM 27808
T
) Isolated from the Andaman Sea
Authors: Lepcha Rinchen T. , Poddar Abhijit , Whitman William B. , Das Subrata K. 
Published: August 2016

ABSTRACT

Idiomarina woesei
strain W11
T
was isolated from the Andaman Sea. Heterotrophic growth was observed at 30 to 37°C and pH 7 to 9. It grows in the presence of 0.5 to 12% (wt/vol) NaCl, and optimum growth occurred at 5 to 6% NaCl. The estimated genome is 2.4 Mb and encodes 2,305 proteins.
Draft Genome Sequence of
Tepidiphilus thermophilus
Strain JHK30
T
(JCM 19170
T
) Isolated from a Terrestrial Hot Spring in India
Authors: Poddar Abhijit , Lepcha Rinchen T. , Whitman William B. , Das Subrata K. 
Published: August 2016

ABSTRACT

Tepidiphilus thermophilus
strain JHK30
T
was isolated from a hot spring at Surajkund, Jharkhand, India. It is a Gram-negative rod, nonsporulating, aerobic, and motile. The estimated genome is 2.3 Mb, with 2,186 protein-coding sequences.
Draft Genome Sequence of
Comamonas thiooxydans
Strain S23
T
(DSM 17888
T
), a Thiosulfate-Oxidizing Bacterium Isolated from a Sulfur Spring in India
Authors: Narayan Kunwar Digvijay , Badhai Jhasketan , Whitman William B. , Das Subrata K. 
Published: August 2016

ABSTRACT

The genus
Comamonas
contains species isolated from various environments, such as termite guts, wetlands, activated sludge, soil, humans, and fresh water. Here, we report the draft genome sequence of
Comamonas thiooxydans
strain S23
T
capable of oxidizing thiosulfate under mixotrophic growth conditions. Based upon draft genome sequencing, the genome is 5.3 Mb and encodes 4,767 proteins. The
Comamonas thiooxydans
whole-genome sequence will help understand the metabolic diversity in sulfur oxidation pathways.
Draft Genome Sequence of Colistin-Resistant
Acinetobacter baumannii
Strain VB22595 Isolated from a Central Line-Associated Bloodstream Infection
Authors: Veeraraghavan Balaji , Anandan Shalini , Ragupathi Naveen Kumar Devanga , Vijayakumar Saranya , Sethuvel Dhiviya Prabaa Muthuirulandi , Biswas Indranil 
Published: August 2016

ABSTRACT

Acinetobacter baumannii
is an important emerging pathogen that causes health care-associated infections. In this study, we determined the genome of a multidrug-resistant clinical strain, VB22595, isolated from a hospital in Southern India. The draft genome indicates that strain VB22595 encodes a genome of ~3.92 Mb in size and does not contain plasmid derived MCR-1 for colistin resistance.
Draft Genome Sequence of
Mycobacterium acapulcensis
Strain CSURP1424
Authors: Asmar Shady , Rascovan Nicolás , Robert Catherine , Drancourt Michel 
Published: August 2016

ABSTRACT

Mycobacterium acapulcensis
is a rapidly growing scotochromogenic acid-fast bacillus. The draft genome of
M. acapulcensis
CSURP1424 comprises 5,290,974 bp, exhibiting a 66.67% G+C content, 4,870 protein-coding genes, and 71 predicted RNA genes.
Complete Genome Sequence of
Serratia marcescens
U36365, a Green Pigment–Producing Strain Isolated from a Patient with Urinary Tract Infection
Authors: Sahni Rani Diana , Amalanathan Rabecca , Devanga Ragupathi Naveen Kumar , Mathai John , Veeraraghavan Balaji , Biswas Indranil 
Published: August 2016

ABSTRACT

Serratia marcescens
is an emerging nosocomial pathogen associated with urinary and respiratory tract infections. In this study, we determined the genome of a green pigment–producing clinical strain, U36365, isolated from a hospital in Southern India.
De novo
assembly of PacBio long-read sequencing indicates that the U36365 genome consists of a chromosome of 5.12 Mbps and no plasmids.
Genome Sequence of
Corynebacterium pseudotuberculosis
Strain PA02 Isolated from an Ovine Host in the Amazon
Authors: Muge Gabriel R. S. , Veras Adonney A. O. , de Sá Pablo H. C. G. , Cavalcante Ana Lídia Queiroz , Alves Jorianne Thyeska Castro , Morais Ezequiel , Silva André G. M. , Guimarães Luís C. , Azevedo Vasco , Folador Adriana Ribeiro Carneiro , Silva Artur , Ramos Rommel T. J. 
Published: August 2016

ABSTRACT

In this work, we report the complete genome sequence of
Corynebacterium pseudotuberculosis
strain PA02 isolated from an ovine host. The genome contains 2,328,435 bp, a 52.2% G+C content, 2,035 coding sequences, 12 rRNA operons, 45 tRNAs, and 14 predicted pseudogenes.
How do males recover from eating disorders? An interview study
Authors: Pettersen Gunn , Wallin Karin , Björk Tabita 
Published: August 2016

ObjectivesThe aim of the current study is to investigate what males experience as helpful in their recovery process from eating disorders (ED).MethodsQualitative in-depth interviews within a phenomenological approach, and using content analysis to excavate overarching text themes.SettingNorway and Sweden.ParticipantsIncluded were 15 males with an age range from 19 to 52 years. Duration of illness varied between 3 and 25 years of experience with anorexia nervosa (n=10), bulimia nervosa (n=4) or ED not otherwise specified (n=1).ResultsThe content analysis revealed four main categories, that is, ‘the need for a change’, ‘a commitment to leave the eating disorder behind’, ‘interpersonal changes’ and ‘searching for a life without an eating disorder’. These categories comprise features like motivation to change, gaining structure in eating situations, a re-learning of personal and interpersonal skills as well as accepting losses and starting a reorientation of identity and meaning. We noted a rather goal-oriented approach to help seeking and a variation in how the males engaged their social network in resolving the challenges associated with the recovery process. Still, the overall nature of the recovery process highly accords with what has been reported for women.DiscussionA clinical implication from our findings is that symptom relief is important to facilitate good circles of improvement, but that the nature of the recovery process would require a wider perspective in treatment. Clinicians may also be informed about challenges related to an instrumental approach to help seeking reported in this study.
Testing the impact of local alcohol licencing policies on reported crime rates in England
Authors: De Vocht F , Heron J , Campbell R , Egan M , Mooney J D , Angus C , Brennan A , Hickman M 
Published: August 2016

BackgroundExcessive alcohol use contributes to public nuisance, antisocial behaviour, and domestic, interpersonal and sexual violence. We test whether licencing policies aimed at restricting its spatial and/or temporal availability, including cumulative impact zones, are associated with reductions in alcohol-related crime.MethodsReported crimes at English lower tier local authority (LTLA) level were used to calculate the rates of reported crimes including alcohol-attributable rates of sexual offences and violence against a person, and public order offences. Financial fraud was included as a control crime not directly associated with alcohol abuse. Each area was classified as to its cumulative licensing policy intensity for 2009–2015 and categorised as ‘passive’, low, medium or high. Crime rates adjusted for area deprivation, outlet density, alcohol-related hospital admissions and population size at baseline were analysed using hierarchical (log-rate) growth modelling.Results284 of 326 LTLAs could be linked and had complete data. From 2009 to 2013 alcohol-related violent and sexual crimes and public order offences rates declined faster in areas with more ‘intense’ policies (about 1.2, 0.10 and 1.7 per 1000 people compared with 0.6, 0.01 and 1.0 per 1000 people in ‘passive’ areas, respectively). Post-2013, the recorded rates increased again. No trends were observed for financial fraud.ConclusionsLocal areas in England with more intense alcohol licensing policies had a stronger decline in rates of violent crimes, sexual crimes and public order offences in the period up to 2013 of the order of 4–6% greater compared with areas where these policies were not in place, but not thereafter.
Improving value-add work and satisfaction in medical residents training: a resident-led quality improvement project employing the lean method to improve hospital supply usage
Authors: Yang Jesse X , Hunt Tristan D , Ting Henry H , Henderson Dan , Finkelstein Julia , Davidson Karina W 
Published: August 2016

ABSTRACTPurposeOur hospital has a Housestaff Quality Council that fosters education and mentorship of medical residents for quality improvement methodologies. Medical residents on our council identified non-standardised storage rooms as a source of medical resident inefficiency and dissatisfaction. To improve value-add work, medical residents implemented and evaluated a quality improvement project of storage room supplies using the lean method.MethodsUsing 5S principle and lean methodology, we designed and implemented a standardised supply cart with physician specific supplies. Between April 2014 and April 2015, 40 random observations (20 residents and 20 nurses) both before and after the standardised supply cart implementation were made. The duration time to locate an item was measured in seconds. The paths taken to locate items were drawn as spaghetti diagrams. Nurses served as our control group given that their supplies were not moved in the implementation. Fifty residents were surveyed to assess their satisfaction.ResultsImplementation of the standardised supply cart reduced the time for residents to locate an item per visit from 50.8 to 30.2 s in one unit (p&lt;0.05) and 127 to 28.3 s in the second unit (p&lt;0.05). Mean time savings per day per resident were 5 min. The spaghetti diagrams indicated that finding supplies became more efficient after the intervention for residents. After the intervention, 92% of residents reported finding supplies more rapidly and 86% reported less frustration with finding supplies.ConclusionsResidents applied the 5S principles and lean methodology to identify and solve a problem that created inefficiency and dissatisfaction.
An overview of the Upper Palaeozoic–Mesozoic stratigraphy of the NE Atlantic region
Authors: Stoker M. S. , Stewart M. A. , Shannon P. M. , Bjerager M. , Nielsen T. , Blischke A. , Hjelstuen B. O. , Gaina C. , McDermott K. , Ólavsdóttir J. 
Published: August 2016

Abstract
This study describes the distribution and stratigraphic range of the Upper Palaeozoic–Mesozoic succession in the NE Atlantic region, and is correlated between conjugate margins and along the axis of the NE Atlantic rift system. The stratigraphic framework has yielded important new constraints on the timing and nature of sedimentary basin development in the NE Atlantic, with implications for rifting and the break-up of the Pangaean supercontinent. From a regional perspective, the Permian–Triassic succession records a northwards transition from an arid interior to a passively subsiding, mixed carbonate–siliciclastic shelf margin. A Late Permian–earliest Triassic rift pulse has regional expression in the stratigraphic record. A fragmentary paralic to shallow-marine Lower Jurassic succession reflects Early Jurassic thermal subsidence and mild extensional tectonism; this was interrupted by widespread Mid-Jurassic uplift and erosion, and followed by an intense phase of Late Jurassic rifting in some (but not all) parts of the NE Atlantic region. The Cretaceous succession is dominated by thick basinal-marine deposits, which accumulated within and along a broad zone of extension and subsidence between Rockall and NE Greenland. There is no evidence for a substantive and continuous rift system along the proto-NE Atlantic until the Late Cretaceous.