bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypertrophy Determination of H9c2 Cardiomyoblast Cell Line Using Wright-Giemsa Staining: An Experience in Developing an Acceptable and Easy-to-handle In-vitro Protocol
Authors: Fadhillah Muhamad Rizqy , Arozal Wawaimuli , Wibowo Heri , Bustami Arleni , Sukmawati Dewi , Kusmardi Kusmardi , Triana Novi , Khatimah Nurul Gusti 
Published: September 2024

Introduction
Cell-size area (CSA) becomes the standard parameter routinely tested in vitro for cardiac hypertrophy studies. Thus, staining is an essential tool for this purpose. As reported in a previous study, immunofluorescence staining is an established method for CSA. However, because it is expensive and requires a specialized microscope, e.g., immunofluorescence or confocal microscope, it is not applicable in a laboratory with limited equipment. Wright-Giemsa staining is a standard procedure in hematology laboratories and is inexpensive and convenient. Here, we shared our experience developing a CSA determination protocol using Wright-Giemsa in H9c2 cardiomyoblast.

Methods
The viability tests were performed on H9c2 to determine the effective dosage of angiotensin II and Irbesartan (standard drug). The H9c2 were divided into three groups: the control group (without either angiotensin II or irbesartan), the negative control (with angiotensin II), and the positive control (with angiotensin II and Irbesartan), triplicate for each group. The cells then are acclimatized overnight, serum-starved for one day, and incubated with angiotensin and irbesartan for 48 hours. Lastly, Wright-Giemsa was observed using a light microscope in three fields. The CSA was determined by three independent observers blindly, statistically different if the p<0.05 using ANOVA ways or Kruskal-Wallis.

Results
After the H9c2 induced by angiotensin-II 1 μM and Irbesartan 1μM, we found the CSA significantly differed among each group (p<0,0001). The negative control has a higher median and interquartile range (IQR) CSA (10.78 (6.79) um2) compared to the control group (median (IQR) 7.27 (4.91) um2) and positive control (median (IQR) 7.849(5.31) um2).

Conclusion
It can be concluded that the Wright-Giemsa might help determine the CSA for in-vitro hypertrophic studies.
Non-invasiv behandling af det slidte tandsæt med adhæsiv teknik
Authors: Pallesen Ulla 
Published: September 2024

Hovedbudskap
Alvorligt tandslid defineres som substantiel mistet tandsubstans og signifikant tab (>1/3) af den kliniske krone
Patologisk tandslid er atypisk for patientens alder og giver anledning til smerte/ubehag eller funktionelle/æstetiske problemer og som – hvis progression – kan give anledning til uønskede komplikationer af øget kompleksitet
Additiv behandling med direkte plast er minimal invasiv, er reversibel, gør det muligt at reparere, holder fremtidige behandlingsmuligheder åbne og er forbundet med begrænsede omkostninger, men behandlingerne er teknikfølsomme og har behov for vedligeholdelse
Subtraktiv behandling med indirekte teknik udføres med materialer, der har bedre mekaniske og æstetiske egenskaber, men behandlingen er mere invasiv, er forbundet med biologiske og økonomiske omkostninger og fejl vil ofte være mere alvorlige
Lokaliseret anteriort tandslid kan ofte behandles ved hjælp af Bjørn Dahl-teknik
Oral Health Policy Framing For Thirumazhisai Town Panchayat, Thiruvallur District, Tamilnadu
Authors: Elumalai Maheswari 
Published: September 2024

Introduction
Oral health is an integral part of general health and no individual can be considered fully healthy while there is active disease in the mouth as “Health is a state of complete physical, mental and social wellbeing and not merely an absence of disease or infirmity. Aim of the study was to assess the prevalence of oral diseases and treatment needs among 5 years, 12 years, 15 years, 35–44 years, and 65–74 years age group population residing in Thirumazhisai town panchayat, India.
Materials and methods
It is a Cross- sectional study conducted in Thirumazhisai town panchayat. Permanent residents with the index age group -5, 12, 15, 35- 44, 65-74 years were included. A systematic random sampling methodology is used to carry out a cross sectional study in Thirumazhisai. Sample size, N= 207. Data collection to be done using a pre-tested questionnaire and clinical examination of study participant. The first part involved collection of demographic information of participant. The dentition status, oral mucosal lesions and treatment needs were assessed based on WHO proforma. All the subjects were examined under adequate illumination using plane mouth mirror and CPITN probe.
Results
In this study, among 35 to 44 years age group 27%(56) were females and 19.4%(40) were males. Prevalence of dental caries was found to be high about 42% among 35-44 years age group. Prevalene of partial denture wearers ( lower denture about 5.3% and upper denture about 4.8%) among 35-44 years old age group population. Prevalence of complete denture (about 2.4% )was found to be more among 65-74 years age group of study population
Conclusion
In the present study, Preventive treatment was highly required among 12 years age group of study subjects.. Urgent treatment was highly required among 35-44 years old study population. Prevalence of dental caries and partial denture wearers was found to be high among 35-44 years old age group of study population.
ДО ПИТАННЯ ДОСЛІДЖЕННЯ МОГИЛИ ГЕТЬМАНА КИРИЛА РОЗУМОВСЬКОГО В БАТУРИНІ: УВЕДЕННЯ В НАУКОВИЙ ОБІГ ВИТЯГУ З ЛИСТА М. ВАЙНШТЕЙНА від 30.06.1927 р.
Authors: Oksin Tetiana 
Published: September 2024

Актуальність дослідження. Питання несанкціонованого розкриття склепу гетьмана Кирила Розумовського досі залишається актуальним. Цій події присвячені ґрунтовні наукові дослідження, зокрема відомих істориків та краєзнавців Ф. Ернста, В. Різниченка, С. Білоконя, О. Коваленка. Результативними стали систематичні напрацювання істориків Національного заповідника «Гетьманська столиця». Проте ця тема потребує подальшого дослідження. Влітку 1927 р. поховання гетьмана України Кирила Розумовського відкрив завідувач Конотопського краєвого музею О. Поплавський. Ця блюзнірська подія обурила й згуртувала українську інтелігенцію, істориків, захисників старовини, небайдужих до збереження пам’яток, зокрема Федора Ернста, Київського краєвого інспектора з охорони пам’яток культури, та директора Чернігівського державного музею Марка Вайнштейна. Мета дослідження полягає в уведенні в науковий обіг нових відомостей та документу про розкриття склепу гетьмана, а саме – витягу з листа завідуючого Чернігівським окрмузеєм М. Вайнштейна до співробітника Лаврського музею в Києві В. Шугаєвського. Методи. У процесі підготовки публікації використано загальнонаукові (аналіз, синтез, порівняльний, класифікації, систематизації) та історичний (проблемно-хронологічний) методи. Наукова новизна зумовлена аналізом та введенням у науковий обіг виявленого документа – витягу з листа Марка Вайнштейна, – який зберігається у Центральному державному архіві вищих органів влади та управління України (м. Київ). Висновки. Підготовлено до друку й уведено в науковий обіг архівний документ – витяг з листа завідуючого Чернігівським окрмузеєм М.І. Вайнштейна до співробітника Лаврського музею в Києві В.А. Шугаєвського про деталі несанкціонованого розкриття могили гетьмана Кирила Розумовського у Воскресенській церкві Батурина від 30.06.1927 р. із фондів ЦДАВО України в м. Київ.
Aborsi: Kajian Dalam Perspektif Hukum Islam Dan Peraturan Perundangan Di Indonesia
Authors: Yudha Ardy Tama  , Rachmat Ihya  
Published: September 2024

ABSTRAK

Tujuan dilakukan penelitian ini adalah untuk mengetahui kajian tentang tindakan aborsi apabila ditinjau dari perspektif hukum Islam serta mengetahui kajian tentang tindakan aborsi apabila ditinjau dari peraturan perundang-undangan di Indonesia. Penelitian menggunakan metode yuridis. Hasil penelitian menunjukkan bahwa kajian tentang tindakan aborsi apabila ditinjau dari perspektif hukum Islam menunjukkan bahwa tahun 2005 Majelis Ulama Indonesia mengeluarkan Fatwa MUI 4/2005 atas pertimbangan bahwa dewasa ini semakin banyak terjadi tindakan aborsi yang dilakukan oleh masyarakat tanpa memperhatikan tuntunan agama. MUI menyatakan bahwa: a) Aborsi haram hukumnya sejak terjadinya implantasi blastosis pada dinding rahim ibu (nidasi); b) Aborsi dibolehkan karena adanya uzur, baik yang bersifat darurat ataupun hajat; Aborsi yang dibolehkan karena uzur sebagaimana dimaksud pada angka 2 hanya boleh dilaksanakan di fasilitas kesehatan yang telah ditunjuk oleh pemerintah; serta d) Aborsi haram hukumnya dilakukan pada kehamilan yang terjadi akibat zina. Hasil penelitian juga menunjukkan bahwa kajian tentang tindakan aborsi apabila ditinjau dari peraturan perundang-undangan di Indonesia meunjukkan bahwa peraturan perundang-undangan di Indonesa yang mengatur tentang tindakan aborsi yakni pada Kitab Undang-undang Hukum Pidana (KUHP) dan Undang-Undang Nomor 36 tahun 2009 Tentang Kesehatan.

Kata kunci: Aborsi, Hukum Islam, Undang-Undang

ABSTRACT

The purpose of this research is to find out the study of abortion when viewed from the perspective of Islamic law and to know the study of abortion when viewed from the laws and regulations in Indonesia. The study used juridical methods. The results showed that the study of abortion when viewed from the perspective of Islamic law showed that in 2005 the Indonesian Ulema Council issued MUI Fatwa 4/2005 on the consideration that today there are more and more abortions carried out by the community without regard to religious guidance. MUI states that: a) Abortion is illegal since the implantation of blastocyst in the mother's uterine wall (nidation); b) Abortion is permissible due to old age, whether emergency or emergency; Abortions that are permitted due to old age as referred to in number 2 may only be carried out in health facilities that have been designated by the government; and d) Unlawful abortions are performed in pregnancies resulting from adultery. The results also show that the study of abortion when viewed from the laws and regulations in Indonesia shows that the laws and regulations in Indonesia that regulate the act of abortion are in the Criminal Code (KUHP) and Law Number 36 of 2009 concerning Health.

Keywords: Abortion, Islamic Law, Law
Sikap Moderat Pengamalan Ajaran Agama Menumbuhkan Moderasi Beragama Sikap Tolerasi Dan Kecintaan Terhadap Kehidupan Bernegara
Authors: Suaidi Suaidi  
Published: September 2024

The realization of religious moderation in a multi-cultural society is a must, with religious moderation, peace can be realized mutual respect, respect and tolerance as a foundation for developing social life in society. With religious moderation, peaceful life goes well among people of different faiths. Religious moderation guides the right religious way for believers. Every religion teaches compassion and peace, so why look at others with hatred. In order to realize interaction with the foundation of religious moderation, a massive movement is needed, one of which is through learning at educational institutions. Research aims to contribute to the growth of harmony among human beings a necessity, because every religion teaches goodness. Religion is not used as a tool to justify behaviour that actually causes unrest and conflict.
Peran Penting Dan Implementasi Empat Pilar Negara Pancasila Dalam Pembangunan Indonesia
Authors: Wiryadi Wiryadi  , Arkaan Fadhlurrahman  , Muhammad Alif Atasyah  , Muhammad Ardan Aldika  
Published: September 2024

In people's lives as Indonesian citizens, there are 4 pillars of the Pancasila State which are very important in the ideology and development of the country, which consist of Pancasila as the state ideology, the 1945 Constitution, the Republic of Indonesia in the form of the Republic of Indonesia which has the sovereignty of the people, Bhinneka Tunggal Ika as the state motto. , and mutual cooperation as the spirit of cooperation in society, is a strong foundation for the development of the Indonesian nation. In the context of development, the 4 Pillars of the Pancasila State provide clear direction and guidance for the government and society to achieve sustainable and inclusive development goals. By strengthening the values of Pancasila, respecting diversity, and implementing mutual cooperation in various areas of development, Indonesia can achieve sustainable progress and realize prosperity for all its people. challenges and opportunities in implementing the 4 Pillars of the Pancasila State in the context of Indonesian development, as well as providing recommendations to increase the effectiveness of this implementation. By contributing to understanding the importance of the 4 Pillars of the Pancasila State in guiding Indonesia's development towards a better future.
Pengaruh Disiplin Kerja dan Lingkungan Kerja Terhadap Kinerja Karyawan pada UD. Karya Pala Kediri
Authors: Imanda Mafesa Milania  , Rike Kusuma Wardhani  , Nuril Aulia Munawaroh  
Published: September 2024

This study aims to determine the effect between work discipline (X1) and work environment (X2) variables on employee performance (Y) at UD Karya Pala Kediri. This type of research is quantitative research. The data collection techniques used are primary data and secondary data. Sample selection using saturated sampling method, the number of samples in the study obtained as many as 34 respondents at UD Karya Pala Kediri. This research data was obtained through questionnaires, interviews, and literature studies. The analysis techniques used are Validity Test, Reliability Test, Classical Assumption Test, Multiple linear regression analysis, t test, F test and Determination coefficient test. The results obtained multiple linear regression equation Y = 11.312 + 0.365X1 + 0.603X2 and the results of the t test variable work discipline and work environment partially significant effect on employee performance. The F test results obtained Fcount results with a significance value of 0.000 <0.05. From the results of the analysis it can be concluded that work discipline and work environment simultaneously and significantly affect employee performance.
Fenomena Eyelash extension: Tinjauan Hukum Kesehatan dan Islam
Authors: Annisa Qurratul’ain  , Hafidzatul Ilmi Kamila  , Siti Aisyah  
Published: September 2024

This article examines the eyelash extension phenomenon from Islamic's perspective and health perspective. Eyelash extension or installing false eyelashes has become a popular beauty trend among women. From a health perspective, eyelash extensions also cause various potential problems. Eyelash extension can damage natural eyelashes, causing eye irritation and infection if not managed properly. In the context of Islamic law, there are discussions regarding the legality of this practice, with some scholars viewing it as a haram act because it involves changing one's natural disposition. However, another view holds that eyelash extensions are acceptable if they do not violate Islamic principles. This article will discuss the health risks associated with eyelash extension. By combining Islamic law and health perspectives, this article aims to provide a better understanding of the eyelash extension phenomenon. Thus, readers can make decisions based on knowledge and careful consideration before deciding whether to do it or leave it.
Inventarisasi Kearifan Lokal Etnis Karo Dalam Pembuatan Minyak Karo Desa Namo Ukur Kecamatan Sei Bingai Kabupaten Langkat
Authors: Nadila Kirani  , Nuriza Dora  
Published: September 2024

Research on the study of Minyak Karo ethnobotany aims to determine the types of plants that are the raw material for making Minyak Karo and its utilization. The method used in the study is a qualitative descriptive method with data collection techniques carried out through an emic approach and an ethical approach to the interview method with producers of Minyak Karo. The results obtained in this study are 42 species from 24 families which are used as ingredients in the production of Minyak Karo. Zingiberaceae is the type most widely used in these herbs. Plan tparts used are leaves (16 species), rhizomes (7 species), roots (6 species), seeds (5 species),fruit (4 species), flowers and tubers (2 species each), and stems (1 species). Benefits of Minyak Karo treat aches, treat colds, reduce heat / fever, heal wounds, dry out and treat sunburn, treat itching, strengthen bones in infants, treat lumbago, treat rheumatism, treat sprains, treat body aches, and treat muscle cramps. Minyak Karo is an external medicine so that its use is enough by way of being rubbed applied or massaged.
Etika Guru Menurut Imam Ibnu Jama’ah As-Syafi’i Dalam Kitab Tadzkirotus Sami Wal Mutakallimi Fi Adabil Alim Wal Muta’alim
Authors: Ahmad Hadziq  , Ahmad Zuhdi  , Ngatoillah Linnaja  
Published: September 2024

The importance of good teacher ethics in the educational process is able to create a positive and productive educational environment that can affect academic learning, moral and social development for students. This research aims to: 1) find out the intraksi between teachers and students according to the book tadzkirotus sami' wal mutakallim fi adabil alim wal muta'alim; 2) knowing good teacher manners so that they are channeled and can set an example as a good example for students; 3) knowing the internal and external factors that can contribute to the teacher so that there is a misappropriation that affects the image of the teacher. This study uses a strong research approach where the type of research is library research. The results of this study show that: 1) good interaction between teachers and students in the book tadzkirotus sami' wal mutakallim fi adabil alim wal muta'alim, one of which is by sincerely intending to seek the pleasure of Allah SWT, patience, and gentleness. In addition, students are taught to always be polite to anyone, as well as interact positively which is emphasized to form relationships full of moral and ethical values. 2) Good teacher ethics can certainly create a positive and productive learning environment, including professionalism and providing a good example to form a good character in students. 3) Internal factors include a lack of ethical awareness and emotional pressure, then external factors, namely economic demands and lack of supervision that can result in the emergence of unethical behavior. To prevent these abuses, it is necessary to increase ethical leadership and increase supervision of character education for teachers and students.
Peran Psikologi Tasawuf Mengenai Kesehatan Mental dan Spiritualitas Generasi Z Pada Era Digital
Authors: Mashita Putri Waluyojati  , Darsista Irma Swari  
Published: September 2024

This research aims to explore the role of Sufism in overcoming the weak mental health and spirituality of generation Z in the digital era. The research method uses qualitative research and is descriptive, namely library research by examining and studying theories from various data sources from journals, books and previously existing research so that it is relevant to the title of this research. Based on the results of this research, it shows that digital technology can disrupt social interactions and spiritual abilities, but also offers opportunities to increase religious knowledge and moral awareness through easy access to information. Sufism, with concepts such as takhalli and tazkiyah al-nafs, can help individuals cleanse their hearts, develop noble qualities, and find inner peace. Supported by easy access to information and interaction, individuals are more aware of mental health. However. The use of digital technology also has a negative impact on mental health, namely individuals experience anxiety, stress, depression and addiction to using digital technology. Therefore, Sufism has great potential in strengthening the spirituality and mental health of Generation Z in the digital era.
Pelaksanaan Pendekatan Contekstual Teaching And Learning (CTL) Dalam Pembelajaran PAI Di SMK Negeri 3 Payakumbuh
Authors: Dinda Ha Yahya  , Junaidi Junaidi  , Muhiddinur Kamal  , Arman Husni  
Published: September 2024

Penelitian ini dilatar belakangi bahwa sebagai siswa yang memiliki tingkat kesadaran yang rendah dalam mengikuti kegiatan pembelajaran terutama kegiatan melakuka praktik yang mengaitkan dengan kehidupan sehari-hari. siswa kurang antusias dalam mengikuti kegiatan pembelajaran dan siswa kurang terlibat dalam proses kegiatan belajar mengajar. Dalam permasalahan yang ada peneliti tertarik untuk meneliti pelaksanaan pendekatan CTL pada mata pelajaran PAI di SMK N 3 Payakumbuh. Penelitian ini bertujuan untuk mengetahui bagaimana penerapan dari model pembelajaran kontekstual dan faktor penghambatnya. Jenis penelitian ini adalah penelitian kualitatif deskriptif yang menggambarkan tentang pelaksanaan pendekatan CTL pada mata pelajaran PAI di SMK N 3 Payakumbuh. Dalam mengumpulkan data peneliti menggunakan teknik observasi, wawancara, dan dokumentasi. Sedangkan untuk menganalisisnya peneliti menggunakan langkah reduksi data, penyajian data dan penarikannya kesimpulan. Untuk menguji kreadibilitas dan kevalidan data peneliti mengecek data yang sudah diperoleh dari berbagai instrumen penelitian yaitu guru, kepala sekolah dan siswa dengan menggukana triangulasi sumber, triangulasi peneliti dan triangulasi metode. Sehingga menghasilkan kesimpulan yang kredibel. Dari penelitian yang telah dilakukan dapat ditarik kesimpulan bahwa pelaksanaan pendekatan Contekstual Teaching and Learning (CTL) pada mata pelajaran PAI di SMK N 3 Payakumbuh dimulai dari perencanaa guru dalam mempersiapkan pembelajaran dengan membuat RPP yang menjadi pedoman guru dalam kegiatan belajar mengajar yang dilakukan di dalam kelas. Pelaksanaan pendekatan CTL adalah siswa mengamati, menganalisis dan menemukan sendiri terkait pembelajaran dalam kegiatan diskusi dan menghubungkan materi dengan kehidupan nyata sehari-hari. adapun faktor penghambat yang ditemukan adalah alokasi waktu yang singkat, kemampuan guru dalam mengkaitkan pembelajaran, siswa bermain-main saat diskusi, siswa bermain handphone dan siswa perempuan lebih aktf dibandingkan dengan siswa laki-laki.
Upaya Guru Pendidikan Agama Islam Dalam Mengatasi Kenakalan Peserta Didik Di SMA Negeri 1 Siotapina
Authors: Asrifa Asrifa  
Published: September 2024

Permasalahan pokok penelitian ini adalah bagaimana upaya guru Pendidikan Agama Islam dalam mengatasi kenakalan peserta didik di SMA Negeri 1 Siotapina. Penelitian ini bertujuan: (1). Mengetahui bagaimana upaya guru Pendidikan Agama Islam dalam mengatasi kenakalan peserta didik SMA Negeri 1 Siotapina, (2). Mengetahui factor-faktor yang mendukung dan penghambat upaya guru Pendidikan Agama Islam dalam mengatasi kenakalan peserta didik SMA Negeri 1 Siotapina.
Penelitian ini adalah penelitian berbentuk deskriptif kualitatif yang menganalisa data secara mendalam tidak berdasarkan angka. Teknik pengumpulan data yang digunakan adalah observasi, interview, dan dokumentasi. Sedangkan Teknik Analisa dapat melalui 3 tahap, yaitu: Data Reduction ( reduksi data), Data Display (penyajian data), dan Conclusion Drawing/verification.
Hasil penelitian ini menunjukkan bahwa: 1). Upaya guru Pendidikan Agama Islam dalam mengatasi kenakalan peserta didik di SMA Negeri 1 Siotapina adalah memberikan bimbingan khusus tentang pemaham kehidupan beragama, berkerja sama dengan guru BK untuk mengetahui asal-ususl siswa, memanggil kedua orang tua siswa, serta pemberian sanksi apabila masih melakukan kenakalan tersebut. 2). Faktor-faktor yang mendukung upaya guru Pendidikan Agama Islam dalam mengatasi kenakalan peserta didik di SMA Negeri 1 Siotapina adalah adanya kerjasama dengan wali kelas, lingkungan sekolah yang baik, dan adanya kebijakan sekolah. 3). factor-faktor yang menghambat adalah tindak lanjut yang kurang maksimal, latar belakang keluarga yang berbeda, pengaruh teknologi, dan kurangnya pengawasan orang tua terhadap kehidupan anak di masyarakat.