bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two-person interactive action recognition based on hypergraph convolutional networks
Authors: Jiangtao Cao , Li Wang , Jinli Dai , Xiaofei Ji 
Published: October 2024

Abstract

Two-person interactive action recognition has broad application prospects in security monitoring, educational assistance etc. Currently, the recognition methods based on the combination of joint point data and graph convolutional networks have made satisfactory progress. However, this type of method still has the problem that the behavioral feature of two-person interaction is not sufficient to represent action information, and the model is also very complex, which cannot be practically applied. To address these problems, a two-person interactive action recognition algorithm based on hypergraph convolutional networks is proposed. Firstly, the input data are symmetrically processed and enhanced, then the hypergraph structure is used to build the two-person interaction hypergraph, which includes the two-person hypergraph part and the two-person interaction relation matrices part. Finally, the two-person interaction hypergraph is deployed into a graph convolutional network with multiple stream inputs, and the Spatial-Temporal Part Attention(STPA) is added to realize the recognition of two-person interaction actions. With fewer parameters, the algorithm can capture both adjacent and long-distance spatiotemporal information within an individual, as well as better utilize interaction information between two people. Experiments on the NTU RGB+D interactive dataset show that the recognition accuracy of this algorithm is 98.24\%, and the inference speed of the model is faster than other methods.
Physicochemical characteristics of surimi from Rainbow trout (Oncorhynchus mykiss) and using surimi for production of novel fisheries products instead of fresh fish for healthy nutrition of Iranian people
Authors: Aberoumand Ali , Adelnia Najmeh 
Published: October 2024

Abstract

Fish processing leads to diversity in products based on consumer needs. Surimi is one of these high-tech intermediate products that can enable the human population to use fish as the most important source of protein. Surimi is concentrated myofibril protein that is extracted from fish meat by a washing process. The purpose of this research was to investigate on produced surimi quality from the fish O. mykiss. The water holding capacity, yield of surimi protein, expressible moisture content, pH value, and chemical composition evaluated with standard methods. The results showed yield of surimi was 43.16%, while the yield of product protein was 99.63%. Water holding capacity in surimi was 88.82%. Chemical analysis showed product protein, fat and ash contents found lower than fresh fish duo to washing steps. The energy level in washing fourth stage (T5) and T1 (control) were 194.99 kcal/100g and 256.51 kcal/100g respectively. The results showed the washing step with salt water improved produced surimi. It can be concluded that produced surimi was suitable for production of good quality fisheries products. It concluded that this fish species was an appropriate raw material for surimi production.
YOLO-E: A Lightweight Object Detection Algorithm for Military Targets
Authors: SUN YONG , WANG JIANZHONG , YOU YU , YU ZIBO , BIAN SHAOBO , WANG ENDI , WU WEICHAO 
Published: October 2024

Abstract

Images of military targets typically exhibit characteristics such as camouflage, varying scales, and uneven distribution, making the task of target detection complex and challenging. Furthermore, the limited computing resources of unmanned platforms, such as drones and ground unmanned vehicles, make it difficult to deploy detectors with large parameter counts on these systems. In this study, we enhanced the components of YOLOv8n and proposed a new lightweight military target detection algorithm named YOLO-E. We constructed a military target dataset composed of armed personnel holding various weapons to facilitate the verification of different algorithms. In our designed algorithm, we applied an efficient multi-scale convolution module in the feature extraction network to improve the detection speed of military targets. Additionally, we designed a head network based on weight sharing, significantly reducing the model parameters. We also proposed a novel bounding box loss function, the Normalized Corner Distance IoU, to further enhance the detection accuracy of military targets. We tested YOLO-E on a self-developed military target dataset. Experimental results showed that compared to the original YOLOv8n algorithm, YOLO-E improved detection accuracy by approximately 1.30\%, increased detection speed by 1.68\%, reduced parameter count by 30.87\%, and decreased computational complexity by 37.33\%. Furthermore, we compared our method with several advanced object detection algorithms. The results demonstrated that YOLO-E also outperformed in terms of comprehensive parameters, real-time performance, and accuracy. The proposed network model provides effective auxiliary support for analyzing battlefield situations.
Replicas for success - microplastics sampling strategy for low-polluted waterbodies
Authors: Barone Marta , Antonsson Egill , Blache Mathis , Buhhalko Natalja , Mischke Steffen , Saarni Saija , Svipsta Sanda , Dimante-Deimantovica Inta 
Published: October 2024

Abstract

There has been a long debate about the importance of reliable microplastic (MP) monitoring in aquatic environments, which includes the need for appropriate replication. This article examines a methodological weakness in surface water MP research, offering a practical recommendation to improve the reliability of environmental MP data and addressing the need for robust sampling methodology, i.e., replication of samples. Two sets (marine and freshwater) of 15 consecutively collected surface water MP samples from Iceland were obtained via net (300 µm) trawling and evaluated to determine the optimal number of replicas needed for precise environmental data acquisition in environments with low MP concentrations. The results revealed significant variability in MP concentrations between trawlings, emphasizing the influence of sporadic occurrences of MPs in surface waters. Increasing the number of replicates can lead to smaller maximal differences between MP concentration estimates, which is particularly crucial in environments with low MP pollution levels. At least three replicate trawlings should be performed per site to obtain representative results. Additionally, estimating filtered water volume using flow meters or alternative devices is recommended over theoretical calculations.
3D Creatine Kinase Imaging (CKI) for In Vivo Whole-Brain Mapping of Creatine Kinase Reaction Rates with 31P-Magnetization Transfer MR Fingerprinting
Authors: Widmaier Mark Stephan , Kaiser Antonia , Pandurevic Pontus , Döring Andre , Huang Zhiwei , Wenz Daniel , Xiao Ying , Jiang Yun , Xin Lijing 
Published: October 2024

Abstract

The creatine kinase (CK) is a key enzyme involved in brain bioenergetics, but imaging its activity noninvasively in the human brain remains a significant challenge. This study aims to advance the magnetization transfer (MT)-31P magnetic resonance fingerprinting (MRF) framework for 3D Creatine Kinase Imaging (CKI), delivering the first whole-brain CK reaction rate maps. The method was implemented and validated on a clinical 7 Tesla MRI scanner with a 49:30-minute acquisition time and the within-session reproducibility was assessed. The CKI method successfully enables the whole-brain mapping of CK reaction rates, showing robust reproducibility with coefficients of variation (CV) below 11% for 25-minute scan sessions. Furthurmore, CKI acquisition provided simultaneous mapping of adenosine triphosphate (ATP) and phosphocreatine (PCr) concentrationratios, PCr longitudinal relaxation time (T1PCr), and phosphorus-based B0 maps at a 7.2 × 7.2 × 20 mm3 resolution. CKI provides, for the first time,3D whole-brain mapping of kCK rates in high resolution, using a user-friendly, push-button approach. A functional CKI (fCKI) study demonstrated the first CK activation cluster map in response to visual stimulation, revealing a mean 17% increase in CK rates in the visual cortex. The novel imaging modalities, CKI and fCKI, have the potential to offer new insights into brain bioenergetics both at rest and during activity.
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Authors: Hoshmand Rafiq Ibrahim  , Tavga Qader Omer  
Published: October 2024

توێژینەوەکە هەوڵدەدات لێکۆڵینەوە لە ڕۆڵی گواستنەوەی ئاسمانی بکات لە هاوردەکردنی زێڕدا لێکۆڵینەوەیەکی شیکارییە لەسەر بۆچوونەکانی کۆمپانیاکانی گواستنەوەی ئاسمانی بۆ کاڵاکان ڕۆڵی گواستنەوەی ئاسمانی وەک گۆڕاوێکی سەربەخۆ نیشان دەدرێت و پەیوەستە بە دوو ڕەهەندەوە، کە بریتین لە ( رادەی سەرکەوتنی بەکارهێنانی ئامرازەکانی گواستنەوەی ئاسمانی، روونکردنەوەی کاریگەرییەکانی بەکارهێنانی ئامرازەکانی گواستنەوەی ئاسمانی، و کۆمپانیاکانی گواستنەوەی ئاسمانی لەخۆگرتبوو، واتە هاوردەکردنی زێڕ، وەک گۆڕاوێک لەسەر بنەمای دوو رەهەند، کە بریتین لە (پشتیوانی و پێشخستنی بازرگانی، دەستڕاگەیشتن و متمانەپێکردن).
بۆ گەیشتن بە ئامانجەکانی توێژینەوەکە پشتی بە ڕێبازە وەسفیی و شیکارییەکان بەستووە لە ڕێبازی وەسفییدا کۆمپانیاکانی هێڵی ئاسمانی بۆ کاڵاکان باس دەکرێن و دەستنیشان دەکرێن، هەرچەندە ژمارەی کۆمپانیاکانی هێڵی ئاسمانی (57) کۆمپانیایە، و فۆڕمێکی راپرسی بەسەریاندا دابەشکرا و پشتیان پێ بەسترا وەک ئامرازێک بۆ کۆکردنەوەی زانیاری، پاشان ئێمە مۆدێلێکی گریمانەییمان پەرەپێدا، پشتمان بە کۆمەڵێک گریمانە بەست، لەوانە:
1- لە ڕووی ئامارییەوە پەیوەندییەکی بەرچاو لە نێوان گواستنەوەی ئاسمانی و هاوردەکردنی زێڕدا هەیە.
2- لە ڕووی ئامارییەوە پەیوەندییەکی بەرچاو هەیە لە نێوان ڕەهەندەکانی ئامرازەکانی گواستنەوەی ئاسمانی و هاوردەکردنی زێڕ.

کاریگەری هەر ڕەهەندێکی ئامرازەکانی گواستنەوەی ئاسمانی لەسەر هاوردەکردنی زێڕ لە ڕێگەی ئاسمانییەوە هەیە.

ڕێبازی شیکاری لەسەر بنەمای شیکردنەوەی ئەو داتا و زانیاریانەی کە بە شێوەیەکی چەندایەتی کۆکراونەتەوە، کە شیکاری دیجیتاڵییە، بە پشتبەستن بە پەیوەندی و هاوکێشە بیرکاری و ئامارییەکان و بەکارهێنانیان بۆ شیکردنەوەی ئەنجامەکان.

وشەی سەرەکی: گواستنەوەی ئاسمانی، هاوردەکردنی زێڕ، کۆمپانیاکانی هێڵی ئاسمانی بۆ کاڵا.
ڕۆڵی ڕوسیا و تورکیا لە ململانێی نێوان ئەرمینیا و ئازەربایجان لەسەر هەرێمی ناگۆرنۆ قەرەباغ
Authors: Ahmed Othman Abdulla , Mohammed Farid Dilshad 
Published: October 2024

پوخته
ئەم توێژینەوەیە هەوڵیداوە لێکۆڵینەوە لە ڕۆڵی ڕوسیا و تورکیا لە ململانێی نێوان ئەرمینیا و ئازەربایجان لەسەر هەرێمی ناگۆرنۆ قەرەباغ بکات. توێژینەوەکە جگە لە خستنەڕووی پاشخانی مێژوویی و هۆکارەکانی ململانێکە لە نێوان هەردوو دەوڵەتی ئازەربایجان و ئەرمینیادا، ئامانجی ئەوەیە کە ڕۆڵی هەریەکە لە ڕوسیا و تورکیا وەک دوو دەوڵەتی سەرەکی ناوچەیی لە ململانێکەدا ڕوونبکاتەوە. پشت بەست بە بەکارهێنانی میتۆدەکانی (مێژوویی، شیکاری ناوەڕۆک) توێژینەوەکە گەیشتووە بەو ئەنجامەی کە بەهۆی جیۆپۆلەتیکی ناوچەکە و بوونی بەرژەوەندییە سیاسی و ئابورییەکانەوە، هەریەکە لە ڕوسیا و تورکیا ڕۆڵی کاریگەر دەگێڕن لە ململانێی نێوان ئەرمینیا و ئازەربایجاندا، بەشێوەیەک ڕوسیا لەسەرەتادا زیاتر وەک ناوبژیوانێک ڕەفتاری کردووە و هەوڵی پاراستنی پەیوەندییەکانی لەگەڵ هەردوو دەوڵەتدا داوە، هەرچەندە پەیوەندییەکانی زیاتر لەگەڵ ئەرمینیا بووە، بەڵام جەنگی روسیا و ئۆکرانیا و هەوڵەکانی ئەرمینیا بۆ نزیک بوونەوە لە دەوڵەتانی ڕۆژئاوا؛ گۆڕانی لە هەڵوێستی ڕوسیادا دروستکردووە، بەجۆرێک ڕوسیا لە ئاست دەست بە سەرداگرتنی هەرێمی قەرەباغ لەلایەن ئازەربایجانەوە بێدەنگی هەڵبژارد و ئەوەش بووە مایەیی نیگەرانی ئەرمینیا. هەرچی تورکیایە هەر لەسەرەتاوە لایەنگری ئازەربایجان بووە دژ بە ئەرمینیا، تورکیا لە ململانێکەدا بە کرداری لەڕووی دیپلۆماسیی و سیاسی و سەربازییەوە هاوکار و پاڵپشتی تەواوی ئازەربایجان بووە، کە ئەوەش هۆکارێکی گرنگ بوو بۆ سەرکەوتنی ئازەربایجان بەسەر ئەرمینیادا لە ململانێیان لەسەر هەرێمی ناگۆرنۆ قەرەباغ.
Delegation of Powers In Higher Education Facilities in Iraq and the Kurdistan Region
Authors: Badrkhan Abdullah Hamza  , Othman Yaseen Ali  
Published: October 2024

بما إن العملية الديمقراطية في اي دولة ما تركز على اللامركزية الإدارية وتوزيع الاختصاصات بصورة شفافة بما ينسجم مع حسن سير المرفق العام بانتظام واطراد وان ذلك من المهام الأساسية للسلطة الإدارية، وإن تفويض في الاختصاصات يسهل تمشية أعمال الادارة في مرافقها.ومرفق التعليم العالي من المرافق الحيوية في الدولة وان التفويض في الاختصاص يسهل تمشية اعمال هذا المرفق وسرعة إنجازها،وان هذا البحث يتناول موضوع تفويض الاختصاص في هذا المرفق في العراق وإقليم كوردستان من حيث التنظيم القانوني لهذا العمل الإداري وان هذا البحث بعد ان يمهدلموضوع تفويض الاختصاص وشروطه وانواعه واليات ممارسته يتناول النظام القانوني للتفويض في مرفق التعليم العالي في العراق وإقليم كوردستان بموجب القانون النافذ،حيث تم تحديد الخلل التشريعي في هذا التنظيم في قانوني وزارة التعليم العالي والبحث العلمي في العراق وإقليم كوردستان. وذكرنا أهم الاستنتاجات التي توصلنا إليها وتقديم بعض التوصيات لسد الثغرات التي لاحظناها اثناء البحث.
Ecofeminism in the Poetic Texts of Qubadi Jalizadeh: The Collection of Baxchakany Malaka Taws
Authors: Ibrahim Ibrahim Mohammed , Pirot Barzan Ali 
Published: October 2024

لێکۆڵینەوەکە بە ناونیشانی (ئیکۆفێمینیزم لە دەقەشیعرییەکانی ''قوبادی جەلیزادە''دا دیوانی ''باخچەکانی مەلەکە تاووس'' بە نمونە) بە ئەنجامگەیەندراوە. ئەم تیۆرە لە پەیوەندی و هاوئاهەنگی ژن و سروشت دەدوێت و ئامانجی پاراستنی ژینگە و کۆتاییهێنانە بە چەوساندنەوەی ژن. پێیوایە کولتوری پیاوسالاری هۆکاری سەرەکی چەوسانەوەی ژن و وێرانکاریی ژینگەی سروشتییە. ئامانجی لێکۆڵینەوەکە: دەرخستنی دید و ڕوانگە ئیکۆفێمینیزمییەکانی شاعیرە، کە لە دووتوێی دەقە شیعرییەکانی ئەم دیوانەدا لەبارەی پرسی چەوسانەوەی ژن و نابوتکردنی سروشت بەیانیکردوون. میتۆدی لێکۆڵینەوەکە: تیۆری ڕەخنەی ئیکۆفێمینیزمییە، کە سودمان لە چەمک و تێڕوانینەکانی ئەم تیۆرە بۆ شیکاری دەقەکان وەرگرتووە.
ئەنجامەکانی لێکۆڵینەوەکە بریتین لە: ئاوێتەکردنی ژن و سروشت بەڕوونی هەستی پێدەکرێت، چ لە ڕووی شەقڵ و سیفەتی هاوبەشی نێوانیان، وەک سەرچاوەی بەرهەمهێنان و بژێوی ژیانی مرۆڤایەتی. ژن وەک هەوێن و چارەسەر بۆ قەیرانی ژینگە و مرۆیی دەبینێت. پرسی ململانێی ژن لەگەڵ کولتوری پیاوسالاری لای شاعیر دیار و بەرچاوە و بەرگری لە مافەکانی ژن دەکات. جۆری پەیوەندی پیاوسالاری لەگەڵ ژن و سروشتدا، بە هۆکاری سەرەکیی نەهامەتییەکان وێنا دەکات.
وشە سەرەکییەکان: ئیکۆفێمینیزم، فێمینیزم، ئیکۆلۆژی، کولتوری پیاوسالاری، شیعرەکانی قوبادی جەلیزادە.
Aktivitas Antifungi Ekstrak Metanol Sarcotheca diversifolia (Miq) Hallier F terhadap Pertumbuhan Candida albicans
Authors: Yuliati  , Kurniatuhadi Rikhsan , Khotimah Siti 
Published: October 2024

Asam Kalimbawan (Sarcotheca diversifolia (Miq) Hallier F.) merupakan tumbuhan liar yang berpotensi sebagai tanaman obat dan diketahui sebagai antioksidan. Tujuan penelitian ini untuk mengetahui potensi antifungi ekstrak metanol buah Sarcotheca diversifolia terhadap Candida albicans. Ekstraksi buah asam kalimbawan (S. diversifolia) dilakukan dengan metode maserasi pada pelarut metanol pro analis. Pengujian antifungi menggunakan metode difusi lubang sumuran di media Saboraud Dextrose Agar. Konsentrasi ekstrak metanol buah S. diversifolia yang diujikan adalah 0,2; 0,4; 0,6; dan 0,8 g/ml, kontrol positif ketokonazol 2%, dan kontrol negatif DMSO 10%. Hasil penelitian memperlihatkan bahwa ekstrak metanol buah asam kalimbawan (S. divesifolia) dapat menghambat pertumbuhan C. albicans melalui pembentukan zona bening di sekitar sumuran. Daya hambat ekstrak metanol buah asam kalimbawan pada ketiga konsentrasi termasuk dalam kategori sedang dengan sifat daya hambat fungistatik. Kekuatan daya hambat dari ekstrak metanol buah asam kalimbawan tersebut memiliki 29-28% dibandingkan dengan daya hambat 2% ketokonazol dengan kategori kuat. Semua konsentrasi uji bersifat fungistatik di jam ke 48. Metabolit sekunder yang terdeteksi pada ekstrak metanol buah S. diversifolia terdiri atas alkaloid, flavonoid, steroid, terpenoid, saponin, dan tanin. Buah asam kalimbawan (S. divesifolia) diduga berpotensi sebagai fungistatik berbasis bahan alam.
Impacto na vida de mulheres ao se tornarem mãe de portadores de necessidades especiais: revisão integrativa
Authors: Lima Mônica Moura da Silveira , Silva Rose Mary Costa Rosa Andrade , Pereira Eliane Ramos , De Deus Vilza Aparecida Handan , De Paulo De Moura Verônica Bessa , Silva Rita de Cássia Ferreira da 
Published: October 2024

Objetivo: analisar estudos referentes ao impacto na vida de mulheres ao se tormarem mãe de portadores de necessidades especiais. Métodos: revisão integrativa por meio das bases de dados: National Library of Medicine National Institutes of Health (PubMed), Medical Literature Analysis and Retrieval System Online (MEDLINE), Cummulative Index to Nursing and Allied Health Literature (CINAHL) e SCOPUS. Resultados: estudos demonstram alterações no cotidiano familiar, social e emocional, como estresse e depressão de mães de filhos portadores de necessidades especiais. O apoio familiar e profissional agregam de maneira significativa o enfrentamento das questões vivenciadas por essa população. Conclusão: o apoio profissional, familiar e social têm impacto direto na saúde física e emocional de mulheres com filhos portadores de necessidades especiais, portanto, compreender questões do mundo vivenciado por essas mulheres visa contribuir na elaboração de políticas públicas para essa população. Contribuições para a prática: identificar questões relacionadas a mulheres mães de pessoas portadoras de necessidades especiais, instrumentaliza gestores e equipe multitisciplinar acerca da proposta e execução de políticas públicas direcionadas a essa população, que muitas vezes se encontra na invisibilidade social.
Palavras-Chave: Adaptação Psicológica; Crianças com Deficiência; Necessidades e Demandas de Serviços de Saúde; Percepção; Relação Materno-Filial.
Synthesis of Novel Indolyl Aryl Sulfone-clubbed Hydrazone Derivatives as Potential HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Molecular Modeling and QSAR Studies
Authors: Ali Hazrat , Latif Abdul , Ali Mumtaz , Ammara  , Waqas Muhammad , Ahmad Manzoor , Khalid Asaad , Khan Ajmal , Al-Harrasi Ahmed 
Published: October 2024

Background:
Non-Nucleoside Reverse Transcriptases Inhibitors (NNRTIs)
are among the most extensively studied enzymes for understanding the biology of Human
Immunodeficiency Viruses (HIV) and designing inhibitors for managing HIV infections.
Indolyl aryl sulfones (IASs), an underexplored class of potent NNRTIs, require
further exploration for the development of newer drugs for HIV.

Aims:
In this context, we synthesized a series of novels by Indolyl Aryl Sulfones with a
hydrazone moiety at the carboxylate site of the indole nucleus. A 2D-QSAR model was
developed to predict Reverse Transcriptase inhibitory activity against wild-type RT
(WT-RT) enzyme.

Method:
The model was successfully applied to predict the HIV-1 inhibitory activity of
known Indolyl Aryl Sulfones. Considering the reliability, robustness, and reproducibility
of the 2D-QSAR model, we made an in-silico prediction of the RT inhibition for our
synthesized compounds (1-14).

Results:
Molecular docking and dynamics simulations established our synthesized Indolyl
Aryl Sulfones, particularly compounds 23, 24, and 28, as effective NNRTIs by stabilizing
HIV reverse transcriptase's structure. Binding energy calculations revealed compound
28 as the strongest inhibitor (-43.21 ± 0.09 kcal/mol), followed by 23 (-40.94 ±
0.10 kcal/mol) and 24 (-39.18±0.08 kcal/mol), emphasizing their binding affinity towards
HIV reverse transcriptase.

Conclusion:
In summary, the synthesized Indolyl Aryl Sulfones, particularly compounds
23, 24, and 28, demonstrate significant potential as Non-Nucleoside Reverse
Transcriptase Inhibitors (NNRTIs) against HIV. These results highlight the promising
role of these compounds in developing novel NNRTIs for managing HIV infections.
Molecular Docking to Predict a Novel Bioactive Compound as an Inhibitor of Beta Catenin in Oral Squamous Cell Carcinoma
Authors: Kannan Neha , Ramalingam Karthikeyan , Ramani Pratibha , E Dilipan 
Published: October 2024

Background:
Efforts aimed at enhancing patient survival have focused on early detection
and diagnosis, followed by prompt treatment of potentially malignant disorders, aiming to halt their
advancement into oral cancer. Recent research has shed light on the pivotal role of the Wnt/B-catenin
signaling pathway in the pathogenesis of potentially malignant oral conditions. This pathway undergoes
a progressive activation process across various degrees of epithelial dysplasia, including mild,
moderate, and severe dysplasia. Beta-catenin (B-catenin) triggers the activation of genes associated
with crucial cellular processes, which include cell growth, viability, differentiation, and migration.

Aims:
In the present study, we aimed to design a novel drug with 3 bioactive compounds through insilico
analysis, assess its efficacy against B-catenin, and develop a new pharmacophore with an emphasis
on B-catenin inhibition.

Materials and Methods:
Based on prior literature, three molecules possessing potent beta-cateninblocking
properties were selected, namely rosmarinic acid, zosterin, and stigmasterol. To evaluate
their binding affinities, molecular docking studies were conducted using the Lamarckian Genetic Algorithm
implemented in AutoDock Tools 1.5.7. Initially, AutoGrid was employed to construct a grid
box for docking purposes. The estimated binding poses of each compound were subjected to clustering
analysis. The interactions between the compounds and beta-catenin were visualized and explored
using PyMOL software.

Results:
Stigmasterol displayed the most substantial binding energy with a value of -3.86 kcal/mol,
followed by rosmarinic acid and zosterin.

Conclusion:
Bioactive components can be used for beta-catenin pathway blocking. Future research
should be carried out to assess these substances in more clinically relevant cancer models.
CLPr_in_ML: Cleft Lip and Palate Reconstructed Features with Machine Learning
Authors: Chen Baitong , Li Ning , Bao Wenzheng 
Published: October 2024

Background:
Cleft lip and palate are two of the most common craniofacial congenital malformations
in humans. It influences tens of millions of patients worldwide. The hazards of this disease
are multifaceted, extending beyond the obvious facial malformation to encompass physiological functions,
oral health, psychological well-being, and social aspects.

Objective:
The primary objective of our study is to demonstrate the importance of imaging in detecting
cleft lip and palate. By observing the morphological and structural abnormalities involving the lip
and palate through imaging methods, this study aims to establish imaging as the primary diagnostic
approach for this disease.

Methods:
In this work, we proposed a novel model to analyze unilateral complete cleft lip and palate
after velopharyngeal closure and non-left lip and palate patients from the Department of Stomatology
of Xuzhou First People's Hospital, Conical Beam CT (CBCT) images in silicon. In order to demonstrate
the generalization, the simulated dataset was constructed using the random disturbance factor,
which is from the actual dataset. We extracted several raw features from CBCT images in detail.
Then, we proposed a novel feature reconstruction method, including six types of reconstructed factors,
to reconstruct the existing features. Then, the reconstructed features weretrained with machine learning
algorithms. Finally, the testing and independent data model was utilized to analyze the performance
of this work.

Results:
By comparing different operator features, the min operator, max operator, average operator, and
all operators can achieve good performances in both the testing set and the independent set.

Conclusion:
With the different operator features, the majority of classification models, including Gradient
Boosting, Hist Gradient Boosting, Multilayer Perceptron, lightGBM, and broadened learning, classification
algorithms can get the well-performances in the selected reconstructed feature operators.