bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal Proximity Promotes Integration of Overlapping Events
Authors: Zeithamova Dagmar , Preston Alison R. 
Published: March 2017

Abstract
Events with overlapping elements can be encoded as two separate representations or linked into an integrated representation, yet we know little about the conditions that promote one form of representation over the other. Here, we tested the hypothesis that the proximity of overlapping events would increase the probability of integration. Participants first established memories for house–object and face–object pairs; half of the pairs were learned 24 hr before an fMRI session, and the other half 30 min before the session. During scanning, participants encoded object–object pairs that overlapped with the initial pairs acquired on the same or prior day. Participants were also scanned as they made inference judgments about the relationships among overlapping pairs learned on the same or different day. Participants were more accurate and faster when inferring relationships among memories learned on the same day relative to those acquired across days, suggesting that temporal proximity promotes integration. Evidence for reactivation of existing memories—as measured by a visual content classifier—was equivalent during encoding of overlapping pairs from the two temporal conditions. In contrast, evidence for integration—as measured by a mnemonic strategy classifier from an independent study [Richter, F. R., Chanales, A. J. H., & Kuhl, B. A. Predicting the integration of overlapping memories by decoding mnemonic processing states during learning. Neuroimage, 124, 323–335, 2016]—was greater for same-day overlapping events, paralleling the behavioral results. During inference itself, activation patterns further differentiated when participants were making inferences about events acquired on the same day versus across days. These findings indicate that temporal proximity of events promotes integration and further influences the neural mechanisms engaged during inference.
Binding by Random Bursts: A Computational Model of Cognitive Control
Authors: Verguts Tom 
Published: March 2017

Abstract
A neural synchrony model of cognitive control is proposed. It construes cognitive control as a higher-level action to synchronize lower-level brain areas. Here, a controller prefrontal area (medial frontal cortex) can synchronize two cortical processing areas. The synchrony is achieved by a random theta frequency-locked neural burst sent to both areas. The choice of areas that receive this burst is determined by lateral frontal cortex. As a result of this synchrony, communication between the two areas becomes more efficient. The model is tested on the classical Stroop cognitive control task, and its operation is explored in several simulations. Both reactive and proactive controls are implemented via theta power modulation. Increasing theta power improves behavioral performance; furthermore, via theta–gamma phase–amplitude coupling, theta also increases gamma frequency power and synchrony in posterior processing areas. Thus, the model solves a central computational problem for cognitive control (how to allow rapid communication between arbitrary brain areas), while making rich contact with behavioral and neurophysiological data.
Noradrenergic Stimulation Impairs Memory Generalization in Women
Authors: Kluen Lisa Marieke , Agorastos Agorastos , Wiedemann Klaus , Schwabe Lars 
Published: March 2017

Abstract
Memory generalization is essential for adaptive decision-making and action. Our ability to generalize across past experiences relies on medial-temporal lobe structures, known to be highly sensitive to stress. Recent evidence suggests that stressful events may indeed interfere with memory generalization. Yet, the mechanisms involved in this generalization impairment are unknown. We tested here whether a pharmacological elevation of major stress mediators—noradrenaline and glucocorticoids—is sufficient to disrupt memory generalization. In a double-blind, placebo-controlled design, healthy men and women received orally a placebo, hydrocortisone, the α2-adrenoceptor antagonist yohimbine that leads to increased noradrenergic stimulation, or both drugs, before they completed an associative learning task probing memory generalization. Drugs left learning performance intact. Yohimbine, however, led to a striking generalization impairment in women, but not in men. Hydrocortisone, in turn, had no effect on memory generalization, neither in men nor in women. The present findings indicate that increased noradrenergic activity, but not cortisol, is sufficient to disrupt memory generalization in a sex-specific manner, with relevant implications for stress-related mental disorders characterized by generalization deficits.
Long-term Correction in Sleep Disturbance Is Sustained After Arthroscopic Rotator Cuff Repair
Authors: Horneff John G. , Tjoumakaris Fotios , Wowkanech Charles , Pepe Matthew , Tucker Bradford , Austin Luke 
Published: March 2017

Background: Sleep disturbance is a major complaint of patients with rotator cuff disease that often leads them to seek treatment. The authors previously reported a prospective analysis of patients who underwent rotator cuff repair and found that sleep disturbance significantly improved at 3 months after surgery. That improvement in sleep was maintained at 6 months. Hypothesis: In the current study, the authors sought to gain medium-term data on this same population at greater than 2 years. The hypotheses were that improvement in sleep disturbance after arthroscopic rotator cuff repair is maintained at 2-year follow-up and that the continued use of narcotic pain medication has a negative effect on sleep quality at 2-year follow-up. Study Design: Case series; Level of evidence, 4. Methods: The original cohort of patients was contacted at a minimum of 24 months after their surgery. Thirty-seven of the 56 patients (66%) involved in the original study were available. Patient outcomes were scored using the Pittsburgh Sleep Quality Index (PSQI), Simple Shoulder Test (SST), visual analog scale (VAS) for pain, and Single Assessment Numeric Evaluation (SANE). The newly obtained scores were compared with prior scores, which ranged from preoperatively to 6 months postoperatively. Results: The statistically significant improvement of the PSQI score demonstrated in our prior analysis at 6 months postoperatively was maintained, with a mean PSQI score of 5.5 for the 37 patients followed beyond 24 months. Of those patients, 41% still had a PSQI score >5, indicative of sleep disturbance. However, even those patients in our study with a PSQI score >5, indicative of sleep disturbance, had an improved mean score of 9.3 at greater than 24 months compared with those patients with a PSQI score >5 at 6 months, who had a mean PSQI score of 11.5 ( P = .13). Both the SST and VAS scores displayed continued improvement at greater than 24 months, with both displaying moderate strength correlation to the PSQI score (VAS: Spearman rho = 0.479, P < .001; SST: Spearman rho = −0.505, P < .001). Regression models again demonstrated the continued use of narcotic pain medication correlating with poor sleep as the difference in the mean PSQI score between users and nonusers increased as postoperative time increased. At greater than 24 months after surgery, patients using narcotics had a mean PSQI score that was 7.4 points higher than narcotic nonusers (standard error [SE] = 1.93; P = .00017). Conclusion: At greater than 24 months, 41% of patients still demonstrated sleep disturbance, with both SST and VAS scores showing improvement. The prolonged use of narcotic medication negatively affects sleep, with a greater effect seen over time.
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo
Authors: Gao Chang , Sun Rui , Xie Ya-Rong , Jiang An-Li , Lin Mei , Li Min , Chen Zheng-Wang , Zhang Ping , Jin Honglin , Feng Jue-Ping 
Published: March 2017

Vglycin, a novel natural polypeptide isolated from pea seeds, possesses antidiabetic properties. Our previous studies have shown that Vglycin can induce the differentiation of human colon adenocarcinoma cells. We aimed to determine the anticancer activity of Vglycin against colon cancer cells and to elucidate related apoptosis-inducing mechanisms. Treatment with purified Vglycin significantly reduced growth, viability, and colony formation of CT-26, SW480, and NCL-H716 colon cancer cells in a dose-dependent manner while down-regulating the expression of proliferating cell nuclear antigen. Mouse xenograft studies showed a 38% inhibition of colon cancer growth in mice treated with Vglycin (20 mg/kg/day) at day 21. Furthermore, the potential mechanisms involved in Vglycin-induced cell apoptosis were examined using cell cycle studies, ultrastructural examination, as well as apoptosis-associated pathway analysis. The results showed that Vglycin significantly promoted apoptosis and G1/S phase cell cycle arrest. As revealed by Western blot, the expression of CDK2 and Cyclin D1 was down-regulated in all three Vglycin-treated colon cancer cells, indicating that the CDK2/Cyclin D1 cell cycle pathway involved in the initiation and progression of colon cancer. Moreover, the inhibition of Vglycin-induced cell proliferation in colon cancer cells was accompanied by alteration of the expression levels of the apoptosis-related proteins Bax, Bcl-2 and Mcl-1, and an increase of caspase-3 activity. Together, our results suggest that Vglycin may be another plant-derived peptide that suppresses colon cancer, supporting the continued investigation of Vglycin as therapeutic agent for colon cancer. Impact statement The antidiabetic properties and the capability of inducing differentiation of human colon adenocarcinoma cells of Vglycin have been reported in our previous studies. However, the anticancer potential of Vglycin on colon cancer cells and its possible related mechanisms were still unknown. In this study, we found that Vglycin could reduce growth, viability, and colony formation or colony size of CT-26, SW480, and NCL-H716 colon cancer cells. Moreover, Vglycin decreased tumor volume by 38% in xenograft mice transplanted with CT-26 cells. The mechanisms of these phenomena may be due to the down-regulated CDK2 and Cyclin D1, G1/S phase cell cycle arrest, and the dysregulated expression of Bax, Bcl-2, and Mcl-1. The findings highlight the anticancer potential of Vglycin against colon cancer cells, and suggest Vglycin may be another colon cancer potential suppressive component of plant-derived peptides.
Evaluation of Metatarsal Head Resurfacing Hemiarthroplasty in the Surgical Treatment of Hallux Rigidus: A Retrospective Study and Mid- to Long-Term Follow-up
Authors: Mermerkaya Musa Uğur , Alkan Erkan , Ayvaz Mehmet 
Published: March 2017

Background. The aim of this study was to evaluate the mid- to long-term outcomes of metatarsal head resurfacing hemiarthroplasty in the surgical treatment of advanced-stage hallux rigidus. Methods. We performed a retrospective review of 57 consecutive patients (25 [43.9%] males, 32 [56.1%] females; mean age, 61.0 ± 6.4 years) who underwent first metatarsal head resurfacing hemiarthroplasty (HemiCAP) for hallux rigidus between August 2007 and September 2010. Sixty-five implantations were performed in 57 patients; 8 patients underwent bilateral procedures. All patients were clinically rated prior to surgery and at the final follow-up visit using the American Orthopaedic Foot and Ankle Society (AOFAS) hallux metatarsophalangeal-interphalangeal scale and first metatarsophalangeal joint range of motion (MTPJ ROM). Results. The median follow-up duration was 81 (range = 8-98) months. The median preoperative AOFAS score was 34 (range = 22-59) points, which had increased to 83 (range = 26-97) points at the final follow-up visit (P < .001). The median preoperative first MTPJ ROM was 25° (range = 15° to 40°), which had increased to 75° (range = 30° to 85°) at the final follow-up visit (P < .001). Conclusions. First MTPJ hemiarthroplasty is an effective treatment method that recovers toe function and first MTPJ ROM, and provides good mid- to long-term functional outcomes. Levels of Evidence: Level IV: Retrospective case series
New or presumed new left bundle branch block in patients with suspected ST-elevation myocardial infarction
Authors: Pera Vijaya K , Larson David M , Sharkey Scott W , Garberich Ross F , Solie Christopher J , Wang Yale L , Traverse Jay H , Poulose Anil K , Henry Timothy D 
Published: March 2017

Aims: Using a comprehensive large prospective regional ST-elevation myocardial infarction (STEMI) system database, we evaluated the prevalence, clinical and angiographic characteristics, and outcomes in patients with ischemic symptoms and new or presumed new left bundle branch block (LBBB). We then tested a new hierarchical diagnosis and triage algorithm to identify more accurately new LBBB patients with an acute culprit lesion. Methods and results: From March 2003 to June 2013, 3903 consecutive STEMI patients were treated using the Minneapolis Heart Institute regional STEMI protocol including 131 patients (3.3%) with new LBBB. These patients had fewer culprit arteries (54.2% vs. 86.4%; P<0.001), were older, more commonly women, with a lower ejection fraction, and more frequently presented with cardiac arrest or heart failure than those without new LBBB. At 1 year follow-up, all-cause mortality accounting for baseline differences was higher in patients with new LBBB (hazard ratio 1.73, 95% confidence interval 1.17–2.58; P=0.007). The new algorithm yielded high sensitivity (97%) and negative predictive value (94%) for identification of a culprit lesion. Using the definition of new LBBB with either hemodynamically unstable features or Sgarbossa concordance criteria on electrocardiogram (ECG), 45% of new LBBB patients would have been treated as ‘STEMI equivalent’. Conclusion: Patients with acute ischemic symptoms and new LBBB represent a high-risk population with unique clinical challenges. If validated in an independent dataset, the new algorithm may improve the diagnostic accuracy regarding reperfusion therapy for new LBBB patients.
Expert Consensus on Predictive Parameters for the Occurrence of a Fall and a Contralateral Hip Fracture 1 and 3 Years After Hip Fracture: A Delphi Survey
Authors: Joeris Alexander , Hurtado-Chong Anahí , Blauth Michael , Goldhahn Joerg , Bodmer Nicolas S. , Bachmann Lucas M. 
Published: March 2017

Background: Early identification of people at risk for a contralateral hip fracture would be desirable to favorably influence patients’ prognosis. A recent systematic review failed to depict stringent patterns of risk parameters to be used for decision-making in clinical practice. Objective: To perform a consensus study using the Delphi method to reach an expert consensus on predictive parameters for the occurrence of a fall and a contralateral hip fracture 1 and 3 years after hip fracture. Methods: A list of potential members of the expert panel was identified based on the authors’ list of a recently conducted systematic review. Participating experts were asked to name parameters determining the probability for a fall and a contralateral hip fracture 1 and 3 years after an occurred hip fracture, separately. Additionally, we asked how those stated parameters should be measured. All mentioned parameters were compiled and sent back to the experts asking them to weight each single parameter by assigning a number between 1 (not important) and 10 (very important). The survey was conducted online using the REDCap software package. We defined expert agreement if the interquartile range of attributed weights for a parameter was ≤2. A relevant parameter had at least a median weight of 8. Results: Twelve experts from 7 countries completed the survey. Presence of fall history and mental and general health status were considered relevant irrespective of the outcome. For falling within 1 and 3 years, the number of medications and residential status were considered relevant, while for fractures within 1 and 3 years, osteoporosis management was considered important. Conclusion: Using the insights gained in this consensus study, empiric studies need to be set up assessing the prognostic value of the selected parameters.
Trends in Public Debt in India: Lessons from Greek Crisis?
Authors: Bhattacharjee Subhomoy , Das Dakshita 
Published: March 2017

There is not much new in the divide in economic literature between fiscal and monetary policy; what is new post-2008 is the emergence of the role of money supply and that of public debt to prominence as the instrument of choice for central banks and the government treasury. To a large degree, money supply and public debt now eclipsed the central role variables such as tax and interest rates had played in the setting of economic policies in countries both developed and developing. While literature is evaluating how the change in the role of these stock parameters to that of policy variables will play out, this article takes up the more mundane task of examining only one of them, which is public debt in the context of India. We believe that there is a key reason to do so. The Indian government has not used public debt as an active policy tool, so far, even as several countries have begun to do so ( Mohanty, 2012 ). Instead, it has held on to a general desideratum of the need to reduce it; borne out of the scare of the balance of payments crisis of 1991. But 25 years after the crisis, it is important to examine if there is a conscious understanding within the government for the need to measure and deploy public debt especially as the room for active deployment of other fiscal tools, namely taxation is circumscribed. By FY14 India’s public debt (centre and states combined), as percentage of GDP, stood at 66.7 per cent; it was 70.6 per cent in FY09. For the sake of comparison, the world’s most indebted countries include Greece, of course, with its general government net debt at 173 per cent of its GDP. Others in the top 20 include Italy, Egypt, Portugal, Spain, France, the United Kingdom, Japan and the United States of America. By current estimates, India does not rank amongst the most indebted countries of the world. But is the position, one of strength or of a passive arrival that offers little or no policy direction to the government? Moreover, this article also argues that in the absence of such direction, there has been a build-up of debt in the economy instead of a reduction. Most of that build-up has been sought to be balanced by recourse to non-tax revenue. As fresh options to tap non-tax revenue dry up, public debt could emerge as the new pressure point for the economy.
Intellectual Potential of Labour Resources in the Modern Russia: Formation, Retention, Utilization
Authors: Аношин  , Anoshin A. 
Published: March 2017

The article considers trends in labour potential of modern Russia from the point of view of formation, preservation and use of intellectual abilities of labour
resources. The author provides that the growth of labour potential at the extensive factor, i.e. in quantitative terms, is becoming less likely to Russia even if the
increase in the birth rate. The author evaluates the possibilities of increasing the employment potential due to the intellectual component that is due to other
factors, related with development of the knowledge economy. In the article the main «points of growth» and problematic issues in the management of intellectual
resources forming a new quality of the labour force. The author marks unintended consequences of labour mobility from the point of view of economic
losses from quantitative imbalances of supply and demand in the modern Russian labour market, associated with the outflow of skilled labour abroad.
Coaching as a Tool for Innovative Leader Development
Authors: Медведева  , Medvedeva E. 
Published: March 2017

Peculiarities of using couching for the purpose of leaders development in organizations. In a highly competitive environment a company would be able to
perform effectively only if there are leaders at all organizational levels, capable of initiating and implementing innovative processes. Coaching is considered
to be one of the innovation leadership fostering tool and grows in popularity worldwide largely due to its remarkable efficiency. The essence of coaching as a
tool for leaders development is revealed, as well as its purpose and process.
The original approach is proposed to emancipate consciousness removing barriers blocking new ideas generation based on a synthesis of the classical methods
of ideas generating. This approach can be used in the process of innovations creation. Also described are the role and methods of choosing professional
coach.
Personnel Recruitment and Selection for an Organization
Authors: Анисимова  , Anisimova Galina , Дроздова  , Drozdova Ekaterina , Палагутина  , Palagutina N. , Мельникова  , Melnikova Marina 
Published: March 2017

As the shortage of competent well-trained employees is becoming more and more acute, so is the problem of recruiting and selecting appropriate personnel
for organizations.
Meanwhile the healthy performance of HRM service, and particularly, well-considered personnel recruitment and selection procedure, helps to slow down
employee turnover, which in turn, positively influences on financial well-being and performance of an organization. Employee turnover can have several effects
on the organizational performance. Dependant on the sphere of activity and jobs of permanently changing employees, this effect can be favorable or virtually
imperceptible, but in certain cases can lead to loss of competitiveness and setback in production. Despite the urgency of the high employee turnover problem,
employee retention programs are still can be found in only few organizations.
The major guidelines for shaping recruitment and selection process are presented in the paper, accompanied by the list of the most popular and efficient
methods of hiring, based on internal and external sources. Especially emphasized are the conditions and stage-after-stage recommendations for proper personnel
selection, making it possible to hire employees, whose personal character traits qualify for the job and/or the set of activities to be implemented. The
above said proves high theoretic and practical importance of the study, carried out by the authors.
Subject matter of civil law
Authors: Хохлов Вадим , Khokhlov Vadim 
Published: March 2017

Given overall evaluation of subject matter of civil law, correlation
with «civil regulation», proposed to continue the establishment
of definition, which coming from the combining interpretation
of private autonomy; referred to fact that civil standards can function
when there are no express reference. Author defends precedence of
law relations as the leading form of legal regulation.
Sunk Cost Fallacy in Driving the World’s Costliest Cars
Authors: Ho Teck-Hua , Png I. P. L. , Reza Sadat 
Published: March 2017

We develop a behavioral model of durable good usage with mental accounting for sunk costs. It predicts higher-than-rational usage that attenuates at a rate that increases with sunk costs. Singapore government policy varied the sunk cost of buying a new car. Using Singapore data, we estimate the elasticity of driving with respect to sunk costs to be 0.048, which implies that government policy between 2009 and 2013 was associated with 86 kilometers per month, or 5.6%, more driving. The results are robust to specifying sunk costs as relative to buyer income and estimation with Hong Kong data. We believe this to be the first field evidence of the sunk cost fallacy in usage of a major durable good. The online appendix is available at https://doi.org/10.1287/mnsc.2016.2651 . This paper was accepted by John List, behavioral economics.