bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymorphous adenocarcinoma of the buccal space—Rare, reported case from our institute
Authors: Sidhu Manjinder Singh , Gupta Sumit , Kane Shubhada , Paul Davinder 
Published: October 2024

ABSTRACT
Polymorphous adenocarcinoma (PAC) of head and neck tumors is a rare salivary gland neoplasm of indolent course. We reported a 63-year-old female who presented as an asymptomatic mass in buccal space. The patient, after metastatic workup, underwent complete excision of the lesion with a negative margin. Postoperative histopathology and immunohistochemistry (IHC) were suggestive of PAC. Presently patient is on follow-up as per a multidisciplinary team decision. To conclude, PAC diagnosis is challenging due to morphological diversity, which necessities IHC. In addition, presently treatment of choice as per the literature review is complete excision.
Evaluation of the use of Music as a Distraction Technique on Dental Anxiety of Children – A Systematic Review and Meta-analysis
Authors: Gokhale Niraj S. , Hugar Shivayogi M. , Saxena Nivedita , Kohli Neha , Patil Vidyavathi H. , Kadam Krishna S. 
Published: October 2024

Background:
The delivery of dental treatment might be negatively impacted by a child’s unwillingness to cooperate. Judging a behavior-guiding strategy that successfully lowers fear and anxiety during dental treatment, results in a change in the child’s attitude toward the treatment, and is also accepted by the parents is necessary given the variety of behavior management strategies that are available. While conventional techniques of behavior modification have been effective, parents’ and dental professionals’ attitudes regarding them are evolving. New nonaversive approaches that are acceptable to parents are thus required. One such approach that may find favor with parents and dental professionals is music therapy.

Methods:
Pertinent medical databases such as PubMed, Cochrane, Embase, and Google Scholar were searched from January 1, 2001, to April 20, 2023, for randomized controlled trials and clinical studies that used music and no music (control) in children undergoing dental treatment. Primary outcomes included a decrease in pulse rate as measured through pulse oximeter in children undergoing dental treatment.

Results:
Through search strategy and screening through titles and abstracts, four randomized clinical trials (Grading of Recommendations, Assessment, Development, and Evaluation [GRADE] high certainty) and eight nonrandomized studies (GRADE high certainty) were included and the pooled results bared that the music pulse rate was significantly reduced in children who were made to listen to the music than those who did not listen to music during dental treatment.

Conclusion:
It was established that music distraction was a better behavior management technique as compared to no music group and instrumental music was better when compared to the nursery rhyme for anxiety reduction in children.
Assessment of larvicidal, growth-suppressing, and developmentaltering bioefficacy of Ageratum houstonianum against Aedes aegypti (L.)
Authors: Shah Vijay Kumar , Gupta Kamal Kumar 
Published: October 2024

Background & objectives:

Aedes aegypti is a major vector responsible for spreading dengue, chikungunya, yellow fever, and Zika viruses worldwide. These illnesses have increased globally due to climate and environmental changes. Vector control and management are the principal tactics for combating mosquitoes-borne diseases in the absence of an effective vaccine. The study aimed to ascertain bioactivities of Ageratum houstonianum leaf acetone extract (AhLAE) against Aedes aegypti.

Methods:
Bioefficacy of AhLAE was tested against fourth instar larvae (L4) of Ae. aegypti using standard WHO protocol. The mortality, growth, and development of larvae, pupae and adults were recorded after exposure to the extract.

Results:
The AhLAE showed larvicidal activity against L4 with LC50 and LC90 values of 401.88 and 691.24 mg/L, respectively. The mortality of the larvae further increased on subsequent days. The AhLAE caused a significant reduction in pupae formation and adult emergence. It also increased the larval duration of L4 and development duration of the pupa formed from the treated L4, indicating its growth-suppressing effects. The impact of the AhLAE was dose-dependent; high concentrations caused reduction in survival and growth of L4. Consequently, the L4-pupal and L4-adult growth indexes decreased. Additionally, the AhLAE induced developmental anomalies in the form of larva-pupa (L-P) intermediates.

Interpretation & conclusion:
The study found that the AhLAE exhibited larvicidal, growth-suppressing, and development-altering activities against Ae. aegypti. The findings suggest the potential of AhALE as a natural insecticidal agent for controlling mosquitoes.
THE IMPACT OF AGING ON THE ANTIOXIDANT PROPERTIES OF ARMENIAN GRAPE BRANDIES
Authors: Shilajyan Hasmik A. , Grigoryan Karine R. 
Published: October 2024

The antioxidant (AH) properties (antioxidant activity, effective concentration, stoichiometry, and the number of reduced DPPH˙ ) of Armenian grape brandy depending on the aging period and radical scavenging kinetics were studied using DPPH assay and the steady-state kinetics method. The relationship between the antioxidant capacity and total polyphenol content was evaluated. The pseudo-first-order rate constant, which describes the main reaction between antioxidant and DPPH˙ , and the second-order rate constant were determined. It was shown that the AH properties and radical scavenging rate of Armenian grape brandy depend on the aging period noticeably for brandies aged for 3–7 years, subsequent aging shows a mild effect.
Effect of Kshoudradi Aschyotana in Arjuna w.s.r to Sub-Conjunctival Haemorrhage: A Randomised Clinical Trial
Authors: A Adeeb , Biradar Arunkumar , Chandran Amal S 
Published: October 2024

Introduction: Subconjunctival haemorrhage (SCH) is a frequent eye condition marked by bleeding beneath the conjunctiva, which causes noticeable discoloration and generally disturbs the affected person. There is currently no specific treatment for SCH in contemporary medical practices. According to Ayurveda, it correlates with Arjuna. It is a rakta pradoshaj vikara (disease caused by vitiated blood) and primarily a pitta-predominant disease manifesting in the Shukla mandala of netra. Objectives: The objective of the study was to compare the efficacy of Kshoudradi Aschyotana with Flurbiprofen Eye Drops in Arjuna with special reference to sub-conjunctival haemorrhage. Materials and Methods: After securing ethical clearance and registering the trial with the CTRI, twenty patients satisfying the inclusion criteria and diagnosed with arjuna were randomised into two groups(10 in each group). The trial group and the control group received Kshoudradi Aschyotana and Flurbiprofen eye drops for 5 days respectively. Objective parameters were assessed using Slit-Lamp photography and the area of the lesions was recorded on the baseline, 5th, and 7th days. The statistical analysis of the area of haemorrhage was conducted using independent and paired t-test for between and within-group analysis respectively. Results: Kshaudraadi Aschyotana has exhibited better results in reducing the area of subconjunctival haemorrhage as compared with flurbiprofen eye drops within five days(P <0.05). Conclusion: The study concludes that Kshaudraadi Aschyotana has beneficial effects in the management of Arjuna as compared with the flurbiprofen eyedrops.
Evidence based Osteogenic, anti adipogenic and anti- senescence action of Centella asiatica extract on Dental pulp stem cells
Authors: Dhok Mayuri , Kharat Avinash , Bhonde Ramesh , Ghangale Nilima 
Published: October 2024

Aim: Centella asiatica linn family of Apiaceae has been used as a traditional medicine as anti-aging remedy to minimize the severity of aging problems. However the effects of Centella asiatica on stem cell differentiation and anti-aging activity are not fully understood. In this investigation we tested the effect of an aqueous extract of Centella asiatica on senescence and osteogenic, chondrogenic and adipogenic differentiation of human dental pulp stem cells ( hDPSCs). Methods: DPSC (n = 10) from the human pulp was treated with various concentrations of Centella asiatica(CA). The cytotoxicity of CA assessed using the MTT. The hDPSCs were then induced to osteogenic, chondrogenic, and adipogenic differentiation for 6 and 21 days using either CA alone or a combination of Centella asiatica with an appropriate induction media. We also evaluated the early and late passage senescence activity of DPSC. Key finding: Our data demonstrate effect of CA extract on adipogenesis, chondrogenesis and osteogenesis, and anti-aging activity. We found that there was initial increase in adipogenesis which was diminished in long-term culture. Similarly, the extract was found to enhance chondrogenesis and osteogenesis and reduced senescence as revealed by β-galactosidase staining. Significance: The present study demonstrated for the first time that the CA extract was able to inhibit adipogenesis, senescence, and accelerated osteogenesis in DPSCs. Overall results show that CA (Mandukaparni) extract can be used to treat osteoporosis, delay aging and reduce obesity.
Investigating the antioxidant properties and GC-MS profile of Indian native medicinal flower Pandanus odorifer and assessing its cytotoxic effects on HT-29 cells
Authors: Kaniyur Chandrasekaran Meenakshi , Vani Raju Manikandan , Duraisamy Boopana , Velliyur Kanniappan Gopalakrishnan , Muthaiyan Ahalliya Rathi 
Published: October 2024

This study aimed to investigate the antioxidant potential and bioactive compounds of Pandanus odorifer flower. The phytochemical investigation includes both qualitative and quantitative experiments. In vitro antioxidant studies were conducted using DPPH, ABTS and hydroxyl methods. The bioactive compounds present in the ethanol extract were identified using GC-MS analysis. The MTT assay was carried out on HT-29 colon cancer cells to investigate the cytotoxic ability of the ethanolic extract. The qualitative phytochemical analysis demonstrated the presence of flavonoids, phenolic compounds, tannins, saponins, steroids, carboxylic acids and cardiac glycosides. The determination of flavonoid showed 400 ± 0.110 mg/g and 250±0.090 mg/g of quercetin equivalent in ethanol and water extracts. Similarly, the determination of phenol exhibited 108±0.210 mg/g and 87±0.173 mg/g gallic acid equivalent in ethanol and water extracts. The total antioxidant capacity revealed 1.6 ± 0.093 mg/g and 1.3± 0.056 mg/g equivalent of ascorbic acid in ethanol and water extracts. The DPPH assay showed IC50 values of 35.06 µg/mL in ethanol and 44.82 µg/mL in water extract. Likewise, the ABTS assay revealed an IC50 value of 42.20 µg/mL and 47.45 µg/mL in ethanol and water extract. The hydroxyl radical assay showed IC50 value of 23.95 µg/mL in ethanol and 36.56 µg/mL in water extract. 22 bioactive compounds were identified using GC-MS analysis based on their similarity index. The ethanolic extract showed greater cytotoxic activity with the IC50 value of 28.08 µg/mL on HT-29 colon cancer cells. This study concludes that the Pandanus odorifer flower extracts exhibited significant antioxidant and cytotoxic property.
Challenges and Opportunities to Work and Industry Practice in Occupational Therapy: A Practitioner Survey
Authors: Fang Yiyang , Liu Jody , Roll Shawn C. 
Published: October 2024

Abstract
Importance: Work and industry (W&I) is a vital yet underrepresented area of occupational therapy practice. Describing the current practice trends, challenges, and opportunities in W&I provides a foundation for future development and advancements.
Objective: To describe the state of W&I occupational therapy practice and to identify challenges and opportunities in this specialty practice area.
Design: Cross-sectional survey conducted June 12 to July 17, 2020.
Setting: Online survey distributed through direct email invitations and online platforms (i.e., CommunOT, LinkedIn).
Participants: One hundred twenty occupational therapy practitioners who had worked in W&I within the most recent 5 yr.
Outcomes and Measures: We used 30 multiple-choice, Likert-scale, and free-response questions across three topics: (1) training, resources, and research; (2) challenges and barriers; and (3) opportunities.
Results: Most respondents were occupational therapy practitioners working in clinical settings with &gt;5 yr of experience; 29.2% identified as male. The most frequently provided services were ergonomic consultation and worksite evaluation; clinic-based W&I services were less frequently provided. Workplace injury prevention, management of psychosocial issues, and employee wellness programs were ranked as the top opportunities for occupational therapy in W&I. A shortage of accessible training and resources to support W&I practice was found, particularly mentoring and occupational therapy–focused research evidence. Maintaining referrals, competition from other professions, and limited support from professional organizations were key challenges.
Conclusions and Relevance: This study illustrates the evolution of W&I occupational therapy practice and highlights an urgent need for increased professional recognition and educational support to maintain occupational therapy’s presence in this practice area.
Plain-Language Summary: In this study, we describe the current practice trends in work and industry occupational therapy practice. We identify challenges related to resources and training in this practice area and provide insights into opportunities for future development. The study findings show the evolution of work and industry occupational therapy practice and highlight an urgent need for more professional recognition and educational support to maintain occupational therapy’s presence in this practice area.
SISTEM INFORMASI GEOGRAFIS PEMETAAN WILAYAH TANAMAN JAGUNG DAN SINGKONG DI KABUPATEN ENDE BERBASIS WEB
Authors: Pati Aju Pankrasia , Jago Tute Kristianus , Radja Melky 
Published: October 2024

Kabupaten Ende merupakan salah satu daerah di Indonesia yang memiliki potensi besar dalam bidang pertanian, khususnya tanaman jagung dan singkong. Untuk memaksimalkan pengelolaan lahan dan hasil pertanian, diperlukan sebuah sistem yang dapat memberikan informasi geografis secara akurat dan real-time. Penelitian ini bertujuan untuk mengembangkan Sistem Informasi Geografis (SIG) yang memetakan wilayah tanaman jagung dan singkong di Kabupaten Ende. Metode penelitian yang digunakan meliputi pengumpulan data primer dan sekunder, pengolahan data spasial menggunakan perangkat lunak SIG, dan analisis hasil pemetaan. Data yang digunakan dalam penelitian ini mencakup data topografi, data penggunaan lahan, dan data produksi yang diperoleh dari instansi terkait serta survei lapangan.Hasil penelitian menunjukkan bahwa SIG yang dikembangkan mampu memetakan distribusi wilayah tanaman jagung dan singkong dengan tingkat akurasi yang tinggi. Peta yang dihasilkan dapat digunakan oleh pemerintah daerah dan petani sebagai alat bantu dalam perencanaan pengelolaan lahan, pemantauan pertumbuhan tanaman, serta mitigasi risiko gagal panen akibat faktor lingkungan.Dengan adanya sistem ini, diharapkan dapat meningkatkan efisiensi dan efektivitas dalam pengelolaan pertanian di Kabupaten Ende, sehingga kontribusi sektor pertanian terhadap perekonomian daerah dapat lebih optimal
The ALOMAR Rayleigh/Mie/Raman lidar: status after 30 years of operation
Authors: Fiedler Jens , Baumgarten Gerd 
Published: October 2024

Abstract. The ALOMAR (Arctic Lidar Observatory for Middle Atmosphere Research) Rayleigh/Mie/Raman (RMR) lidar is an active remote sensing instrument for investigation of the Arctic middle atmosphere on a routine basis during day and night. It was installed on the island of Andøya in northern Norway (69° N, 16° E) in summer 1994. During the past 30 years of operation, more than 20 200 h of atmospheric data have been measured, approximately 60 % thereof during sunlit conditions. At present, the RMR lidar is the only system measuring aerosols, temperature, and horizontal winds simultaneously and during daytime in the middle atmosphere. We report on the current status of the lidar, including major upgrades made during recent years. This involves a new generation of power lasers and new systems for synchronization, data acquisition, and spectral monitoring of each single laser pulse. Lidar measurements benefit significantly from a control system for augmented operation with automated rule-based decisions, which allows complete remote operation of the lidar. This was necessary in particular during the COVID-19 pandemic, as it was impossible to access the lidar from outside Norway for almost 1.5 years. We show examples that illustrate the performance of the RMR lidar in investigating aerosol layers, temperature, and horizontal winds, partly with a time resolution below 1 s.
Assessing groundwater level modelling using a 1-D convolutional neural network (CNN): linking model performances to geospatial and time series features
Authors: Gomez Mariana , Nölscher Maximilian , Hartmann Andreas , Broda Stefan 
Published: October 2024

Abstract. Groundwater level (GWL) forecasting with machine learning has been widely studied due to its generally accurate results and low input data requirements. Furthermore, machine learning models for this purpose can be set up and trained quickly compared to the effort required for process-based numerical models. Despite demonstrating high performance at specific locations, applying the same model architecture to multiple sites across a regional area can lead to varying accuracies. The reasons behind this discrepancy in model performance have been scarcely examined in previous studies. Here, we explore the relationship between model performance and the geospatial and time series features of the sites. Using precipitation (P) and temperature (T) as predictors, we model monthly groundwater levels at approximately 500 observation wells in Lower Saxony, Germany, applying a 1-D convolutional neural network (CNN) with a fixed architecture and hyperparameters tuned for each time series individually. The GWL observations range from 21 to 71 years, resulting in variable test and training dataset time ranges. The performances are evaluated against selected geospatial characteristics (e.g. land cover, distance to waterworks, and leaf area index) and time series features (e.g. autocorrelation, flat spots, and number of peaks) using Pearson correlation coefficients. Results indicate that model performance is negatively influenced at sites near waterworks and densely vegetated areas. Longer subsequences of GWL measurements above or below the mean negatively impact the model accuracy. Besides, GWL time series containing more irregular patterns and with a higher number of peaks might lead to higher model performances, possibly due to a closer link with precipitation dynamics. As deep learning models are known to be black-box models missing the understanding of physical processes, our work provides new insights into how geospatial and time series features link to the input–output relationship of a GWL forecasting model.
Antimicrobial Efficiency of Hypochlorous Acid Incorporation and its Effect on Surface Properties of Irreversible Hydrocolloid Materials
Authors: M. Abass Shorouq , S. Khalaf Bayan , I. Issa Moamin , Mohammed Al-Khafaji Aseel 
Published: October 2024

Objective: Conventional approaches for disinfection, including spraying and immersion, resulted in only surface disinfection of impressions. As a result, self-disinfecting impression materials incorporated with antimicrobial compounds require more extensive studies. The incorporation of a disinfectant into irreversible hydrocolloid impression materials could eliminate the need for the disinfection step by conventional approaches, including spraying and immersion which only result in surface disinfection of impressions. The study was aimed to investigate the effect of incorporation of hypochlorous acid in irreversible hydrocolloid materials on antimicrobial efficiency, detail reproduction, and dimensional stability.
Materials and Methods: Hypochlorous acid (HOCl) was used in two concentrations, 100 ppm and 200 ppm, and mixed with alginate powder to compare with the control group (distilled water mixed with alginate). Candida albicans, Staphylococcus aureus, and Pseudomonas aeruginosawere chosen for assessing the antimicrobial activity with the disk diffusion test. In addition, the dimensional stability and reproduction of details were tested.
Results: The results revealed that both HOCl concentrations of 100 ppm and 200 ppm imposed significant antimicrobial activity against all three tested microorganisms. There was no significant difference regarding reproduction of details, but the addition of the antimicrobial had a significant adverse effect on the alginate’s dimensional stability.

Conclusion: It may be concluded that the incorporation of HOCL into irreversible hydrocolloid impression material resulted in an impression with antimicrobial activity. In addition, there was no effect on the impression materials ability to reproduce surface details, but the antimicrobial addition may affect its dimensional stability.
Asociación entre el biotipo facial y la clase esqueletal en pacientes entre 11 y 30 años atendidos en la Clínica de especialidades de ortodoncia UDD entre los años 2015 y 2020
Authors: Consigliere Huber Valentina , Donoso Wiedmaier Magdalena , Veloso Casado Valentina , Finkelstein Cañas Andrea , Ramos-Rojas José Tomás 
Published: October 2024

Introducción: En ortodoncia, es importante la concordancia entre la clase esqueletal y biotipo facial para establecer un buen diagnóstico y tratamiento, para así corregir problemas de estética, dinámica mandibular y maloclusiones. Objetivos: Evaluar la asociación entre el biotipo facial y la clase esquelética de paciente chilenos de 11 a 30 años que fueron atendidos en la clínica de especialidades en ortodoncia de la UDD. Metodología: Se realizó un estudio transversal analizando la asociación entre biotipo facial y clase esqueletal de pacientes atendidos en la CESP. Se realizó un análisis descriptivo de las frecuencias absolutas y relativas de las distintas categorías y sus combinaciones. La asociación estadística fue determinada a través de la prueba x2. Resultados: Se incluyeron 290 participantes, 55.5% de sexo femenino, con una media de edad de 19,6 años. El biotipo más prevalente fue dolicofacial y la clase esqueletal fue clase II. En cuanto a la asociación 67 pacientes fueron clase II y dolicofacial, siendo la asociación más frecuente. Un 57.24 % no presento concordancia. Discusión: La normalidad en base al biotipo facial y clase esqueletal no fue predominante, esto se relaciona con problemas de maloclusión, estética y TTM. La terapia interceptiva y la cirugía ortognática son opciones para tratar las anomalías dentomaxilares dependiendo de factores como la edad y severidad de la condición. Conclusión: el 57,24% de la población no presenta una concordancia entre biotipo facial y clase esqueletal, por lo que un correcto diagnóstico, planificación y plan de tratamiento son esenciales para obtener resultados favorables.