bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategies for modern operations management
Authors: Chiarini Andrea , Vagnoni Emidia 
Published: April 2017

Purpose
This research enlarges the debate on the operations management strategies pursued by manufacturing companies. The purpose of this paper is to focus on issues concerning servitisation and customisation, enterprise resource planning (ERP) and Lean-agile, supply chain orchestration, corporate social responsibility (CSR) and Lean for design management.

Design/methodology/approach
A questionnaire of eight questions which stemmed from a literature review was completed by 152 senior operations managers from 120 large European manufacturing companies. Responses were scaled from strongly agree to strongly disagree. The results were tested for reliability using Cronbach’s α test. The questions were tested through a one-sample t-test.

Findings
The 152 respondents consider servitisation and standardisation to be a trade-off. They consider integration of ERP strategies with Lean and agile systems and customised products/processes to be difficult. Furthermore, suppliers’ orchestration is considered not that suitable for manufacturing companies and suppliers’ CSR performance measurement excessive. By contrast, a CSR internal performance measurement is helpful for increasing sales. The respondents also indicate that there is a lack of Lean tools for design and development processes and Six Sigma is the only strategy for improving quality performance in design and development processes.

Research limitations/implications
The findings are applicable only to the manufacturing sector. The findings of this research indicate many avenues of research for scholars.

Practical implications
The findings can be very useful for manufacturing operations managers deciding their future strategies on operations.

Originality/value
Findings related to servitisation and customisation, ERP and Lean-agile, supply orchestration for manufacturing companies and Lean and agile for product design are original and open a valuable debate.
Tensions in managerial attention in a company in crisis
Authors: Bourmistrov Anatoli , Kaarbøe Katarina 
Published: April 2017

PurposeThe purpose of this paper is to understand how in a situation of a crisis can Management Accounting Systems (MAS) create tensions in attention to information between top and line managers.Design/methodology/approachThe study is based on a field study.FindingsThe findings based on an attention-based view on organizations demonstrate how change to an MAS introduced to handle the crisis failed to integrate top and line managers’ attention toward the common issues. Tightening of budget control was an expected response in such a situation. However, this change produced rather the opposite result – attention to information articulated by the top and line managers became even more disintegrated. This was visible in terms of different interpretations of both the reasons and the strategy of how to get out of the crisis – this is what we call a tension in attention.Research limitations/implicationsThe study is subject to the usual limitations of case-based research.Practical implicationsImplications from the study is that there is a need for caution about how managers move in the beginning of the crisis because the initial response sets a tone and trajectory of the crisis. In practice, this means that sense making processes are important in an early stage of a crisis to avoid tensions in attention between different groups in the organization.Originality/valueThe authors argued that little research has been conducted so far regarding what information managers focus their attention on in organizations under financial distress conditions. The originality is the use of an attention-based view together with organizational psychology to understand this area.
Positive and negative effects of affective and continuance brand commitment in a service context
Authors: Raju Sekar 
Published: April 2017

PurposeThe findings from the brand commitment literature suggest that the outcomes of commitment are not always favorable to the brand. This research aims to integrate the multi-component view of commitment with the relationship investment model to suggest a possible explanation to understand the mixed findings in the literature.
Design/methodology/approachA random mall intercept method was used. A total of 1,000 surveys were distributed to participants to answer and mail back. The data were analyzed using structural equation modeling.
FindingsThis research finds that consumers in affective and continuance commitment relationships differ significantly from each other both from an antecedent and an outcome perspective. Specifically, affective commitment consumers were more willing to make sacrifices, felt better about their brand relationship, held less favorable impressions about a competitor brand and were likely to continue patronizing the brand in the future. Continuance commitment consumers were unwilling to make sacrifices for the relationship, did not feel that their brand relationship was superior, were not keen on continuing the brand relationship in the future and were more favorable toward a competitor brand.
Originality/valueThis paper contributes to the development of theory on brand commitment and provides a way to understand the mixed findings in the literature. Importantly, by examining the antecedents and outcomes, a more complete understanding of affective and continuance commitment is possible. The marketing manager benefits by understanding that not all brand commitments are the same. This research might help them to think more broadly about important brand-related outcomes in a service setting.
Knowledge management as a factor for the formulation and implementation of organization strategy
Authors: Dayan Rony , Heisig Peter , Matos Florinda 
Published: April 2017

Purpose
Knowledge management (KM) and organization strategy are both important to the success of an organization. This study aims to assess the research needs of their interrelationship.

Design/methodology/approach
The research is based on a collection of over 200 interviews of KM worldwide experts. Their inputs have been categorized based on the frequency of their occurrence.

Findings
This study looked at the research themes recommended by the experts and concluded that KM is to be regarded as a factor for the formulation and implementation of the organization strategy.

Research limitations/implications
The sample of scholars and practitioners interviewed, the analysis approach used and the use of broad questions and dimensions are some of the limitations of this study. Nevertheless, a variety of effects KM has on the formulation and implementation of company strategy has emerged.

Practical implications
Organizations would improve their chances of success in a changing and competitive world by integrating the KM approach, methods and goals within the articulation of their strategy.

Originality/value
This study is original in variety because of the wide demographic sample supplied, and to its involvement both of KM academic experts as well as of practitioners. Its value is in the recommendations on the research of KM and organization strategy that would be of value, not only to organizations looking for ways to make their strategy more effective but also to those willing to implement KM in a better way.
Citation classics published in knowledge management journals. Part III: author survey
Authors: Serenko Alexander , Dumay John 
Published: April 2017

PurposeThis paper is the third part of a series of works investigating the top 100 knowledge management (KM) citation classic articles. The purpose of this paper is to understand why KM citation classics are well-cited.Design/methodology/approachThe results of a survey of 58 KM citation classic authors were reported as descriptive statistics and subjected to content analysis.FindingsAn archetype of a KM citation classic author was constructed including demographics, personal characteristics, motivation and work preferences. There is a need for developing novel ideas in KM research. Timeliness of a publication is directly linked to its future impact. Editors should involve citation classics authors as reviewers, and KM researchers should improve their citation practices. Serendipity played a very important role in early KM research, especially from the perspective of discovering new and interesting phenomena.Research limitations/implicationsWhereas the importance of serendipity is not questioned, future KM researchers should rely more on a formal, meticulous and well-planned research approach rather than on the hope of making a discovery by accident or luck. KM citation classics authors relied on serendipity to form the foundation of the discipline, but extending their work requires formal and structured inquiries.Practical implicationsMany authors conducted research to solve a problem to serve the needs of both practice and academia, rather than being overly theoretical.Originality/valueBecause KM researchers can no longer rely on past bibliometric theories, this paper helps understand why specific articles are highly cited and recommends how to conduct and develop future KM research that has impact.
Business group affiliation, earnings management and audit quality: evidence from Bangladesh
Authors: Muttakin Mohammad Badrul , Khan Arifur , Mihret Dessalegn Getie 
Published: April 2017

PurposeThis study aims to investigate the moderating role of audit quality on the association between business group affiliation of firms and earnings management in the South Asian emerging economy of Bangladesh.Design/methodology/approachA usable sample of 917 firm-year observations was drawn from companies listed on the Dhaka Stock Exchange from 2005 to 2013. Data were collected from the annual reports of sample companies. Earnings management was measured using the absolute value of discretionary accruals, and two proxies were used to measure audit quality: auditor size and industry specialisation.FindingsResults showed that the level of discretionary accruals is positively associated with business group affiliation status, and higher audit quality reduces this association. This suggests that in environments without strong investor protection, complex ownership structures create opportunities for controlling shareholders to expropriate minority shareholders. The controlling shareholders could then mask this practice through earnings management. The findings also show that in environments lacking strong investor protection, audit quality can help improve earnings quality for group-affiliated firms.Practical implicationsThe results suggest that financial statement users need to consider audit quality for a reasonable evaluation of the earnings quality of business groups. The study also informs regulators by illuminating audit quality as a key area of focus in any effort directed at enhancing stock market efficiency through improved earnings quality in environments where business group affiliation is prevalent.Originality/valueThis study documents empirical evidence on the moderating effect of audit quality on the positive association between business group affiliation and earnings management.
Time-driven activity-based costing
Authors: Barros Rúben Silva , Ferreira Ana Maria Dias Simões da Costa 
Published: April 2017

Purpose
By designing a pilot time-driven activity-based costing (TDABC) model, this study aims to examine in depth the suitability and the complexity of TDABC in a manufacturing company.

Design/methodology/approach
To obtain a deeper understanding on the matters to analyse, this research adopts an interventionist approach. The host organisation is GP, a Portuguese company in the frozen food sector.

Findings
The authors’ experience allows them to assert that TDABC is suitable for a manufacturing company and it is able to deal with the variability of the industrial processes. Nonetheless, through a comparison with the models presented in the literature, TDABC appears to be more complex for manufacturing. The authors argue that this happens for two reasons. First, the two types of resources (human labour and machinery) used in production areas create a need to split tasks and to create two equations for each process, something that does not happen in service companies. Second, times are difficult to individualise for certain highly automated procedures, which could also give rise to some errors.

Research limitations/implications
The designed model is compared to other models presented in the literature.

Practical implications
This study shows a real example of TDABC in manufacturing and the procedural innovation of the time equations.

Originality/value
As the TDABC literature has been mostly focused on examples of service companies, the authors examine the technical suitability and the complexity of TDABC in manufacturing companies.
Proteomic composition of the acrostyle: Novel approaches to identify cuticular proteins involved in virus–insect interactions
Authors: Webster Craig Graham , Thillier Mäelle , Pirolles Elodie , Cayrol Bastien , Blanc Stéphane , Uzest Marilyne 
Published: April 2017

AbstractThe acrostyle is a distinct anatomical region present on the cuticle at the inner face of the common food/salivary canal at the tip of aphid maxillary stylets. This conserved structure is of particular interest as it harbors the protein receptors of at least 1 plant virus, Cauliflower mosaic virus, and presumably has other roles in plant–insect interactions. Previously we reported immunolabeling of a highly conserved motif of cuticular proteins from the CPR family (named for the presence of a Rebers and Riddiford consensus) within the acrostyle. Here we report the development of novel tools to further study the proteomic composition of this region and to identify proteins involved in insect‐virus interactions. Using a series of antibodies against cuticular proteins from the RR‐2 subfamily, we identified additional peptides present within the acrostyle. Our results demonstrated that the acrostyle is a complex structure containing multiple domains of cuticular proteins accessible for interaction. In addition, an array of overlapping peptides, which covers the diversity of the majority of the RR‐2 subfamily, was developed as a generic tool to characterize cuticular protein/pathogen interactions. Upon probing this array with Cucumber mosaic virus particles, consensus peptide sequences from hybridizing peptides were identified. Use of these novel tools has extended our knowledge of the proteomic composition of insect maxillary stylets and identified sequences that could be involved in virus binding, thus contributing to further elucidation of the various properties and functions of the acrostyle.
RVX 208: A novel BET protein inhibitor, role as an inducer of apo A‐I/HDL and beyond
Authors: Ghosh Gopal C. , Bhadra Rajarshi , Ghosh Raktim K. , Banerjee Kinjal , Gupta Anjan 
Published: April 2017

SummaryLow‐density cholesterol (LDL) has been the prime target of currently available lipid‐lowering therapies although current research is expanding the focus beyond LDL lowering and has included high‐density cholesterol (HDL) also as the target. Bromo and extra‐terminal (BET) proteins are implicated in the regulation of transcription of several regulatory genes and regulation of proinflammatory pathways. As atherosclerosis is an inflammatory pathway and studies showed that BET inhibition has a role in inhibiting inflammation, the concept of BET inhibition came in the field of atherosclerosis. RVX 208 is a novel, orally active, BET protein inhibitor and the only BET inhibitor currently available in the field of atherosclerosis. RVX 208 acts primarily by increasing apo A‐I (apolipoprotein A‐I) and HDL levels. RVX 208 has a novel action of increasing larger, more cardio‐protective HDL particles. Post hoc analysis of Phase II trials also showed that RVX 208 reduced major adverse cardiovascular events (MACE) in treated patients, over and above that of apo A‐I/HDL increasing action. This MACE reducing actions of RVX 208 were largely due to its novel anti‐inflammatory actions. Currently, a phase III trial, BETonMACE, is recruiting patients to look for the effects of RVX 208 in patients with increased risk of atherosclerotic cardiovascular disease. So BET inhibitors act in multiple ways to inhibit and modulate atherosclerosis and would be an emerging and potential option in the management of multifactorial disease like coronary artery disease by inhibiting a single substrate. But we need long‐term phase III trial data's to look for effects on real‐world patients.
Ivabradine vs metoprolol in patients with acute inferior wall myocardial infarction—“Expanding arena for ivabradine”
Authors: Priti Kumari , Ranwa Bhanwar L. , Gokhroo Rajendra K. , Kishore Kamal , Bisht Devendra Singh , Gupta Sajal 
Published: April 2017

SummaryBackgroundAtrioventricular (AV) blocks are of concern with the use of beta blockers in inferior wall myocardial infarction (MI). Ivabradine lowers heart rate with a lesser risk of AV blocks.ObjectivesTo compare ivabradine with metoprolol in acute inferior wall MI in terms of feasibility, tolerability, and efficacy.MethodsIt was a prospective double‐blind single‐center randomized controlled study. Of 1032 patients with acute inferior wall MI, 468 eligible patients were randomized in 1:1 manner to ivabradine (group A) and metoprolol (group B). Intention to treat analysis of 426 patients (group A‐232 and group B‐232) was performed. The primary endpoint was 30‐day incidence of major adverse cardiovascular events including death, reinfarction, complete heart block (CHB), and heart failure. Secondary endpoints included 30 days incidence of recurrent angina, readmission, first‐ or second‐degree AV block, and tachyarrhythmias.ResultsBoth the drugs decreased the mean heart rate to 62.22±2.95 (group A) vs 62.53±3.59 (group B) beats per minute (P=0.33). Ejection fraction improved in both the groups (5.15±1.93% in group A vs 5.52±2.18% in group B, P=0.065). The two groups did not differ significantly in their primary endpoints in terms of death (group A=1.72% vs group B=1.72%, OR=1.00, 95% CI=0.25‐4.05, P=1.00), reinfarction (group A=0.86% vs group B=0.86%, OR=1.00, 95% CI=0.14‐7.16, P=1.00), heart failure (group A=4.31% vs group B=2.59%, OR=1.70, 95% CI=0.61‐4.75, P=0.31), or CHB (0% vs 2.59%, OR=0.07, 95% CI=0.00‐1.34, P=0.08). There were no significant differences in the secondary endpoints of recurrent angina, readmission, and tachyarrhythmias except for more first‐ and second‐degree AV blocks with metoprolol (12.93% vs 2.59%, OR=5.59, 95% CI=2.28‐13.72, P=0.0002).ConclusionsIvabradine is well tolerated and equally effective as metoprolol in acute inferior wall ST elevation myocardial infarction patients for lowering the heart rate with lesser risk of AV blocks.
Assessment of vascular response to BiOSS LIM C® stents vs Orsiro® stents in the porcine coronary artery model
Authors: Bil Jacek , Gil Robert J. , Pawlowski Tomasz , Milewski Krzysztof P. 
Published: April 2017

SummaryAimsThe optimal treatment strategy for coronary bifurcation lesions is still unknown. The aim of the study was to assess applicability of the new cobalt‐chromium version of the sirolimus‐eluting dedicated bifurcation BiOSS® LIM C stent in comparison with regular sirolimus‐eluting Orsiro® stent in a porcine coronary model.MethodsA total of 13 BiOSS® LIM C stents and 6 Orsiro® stents were implanted in normal nonatherosclerotic porcine straight coronary arteries of six animals using 1.2:1.0 stent‐to‐artery ratio. Stent geometry and morphology were evaluated by Faxitron imaging. Vascular response was assessed by quantitative coronary angiography (QCA), optical coherence tomography (OCT), and histological analyses.ResultsOCT performed at 28 days confirmed that all stents were patent with no signs of thrombus. In morphometric analysis, no differences between groups regarding stent diameter (P=.141), neointima area (P=.247), % area stenosis (P=.293), or % diameter stenosis (P=.069) were observed. Also, no significant differences were noted between groups regarding their histopathology scores. The injury and inflammation scores were low (mean grade<1) in all groups.ConclusionsThe novel BiOSS® LIM C stent demonstrates good short‐term vascular effects in a porcine coronary bifurcation model which are comparable with Orsiro® stents.
External Validation of the DHAKA Score for Diagnosing Severe Dehydration in Children with Acute Diarrhea in Resource‐limited Settings
Authors: Levine Adam C. , Glavis‐Bloom Justin , Modi Payal , Nasrin Sabiha , Atika Bita , Rege Soham , Schmid Christopher H. , Alam Nur H. 
Published: April 2017

BackgroundAcute diarrhea remains both common and deadly in children worldwide. Proper treatment depends on accurately assessing dehydration status. Current World Health Organization (WHO) guidelines include an algorithm for classifying children as having no, some, or severe dehydration, which has never been properly validated. The Dehydration: Assessing Kids Accurately (DHAKA) study recently derived a new scoring system for dehydration in children, but it requires external validation.MethodsOur study enrolled a random sample of children with acute diarrhea in Bangladesh. Local nurses prospectively applied both the DHAKA score and the WHO algorithm to children on arrival and obtained serial weights as they were rehydrated. The percent weight change with rehydration was used to classify subjects with severe (>9%) dehydration, some (3%–9%) dehydration, or no (<3%) dehydration. Test characteristics and the area under receiver operator characteristic curves (AUC) were calculated and compared for both diagnostic tools.ResultsA total of 546 children were enrolled, with 488 included in the final analysis. The DHAKA score had an AUC of 0.77 compared to 0.72 for the WHO algorithm for the diagnosis of severe dehydration (p = 0.001) and 0.84 compared to 0.62 for the diagnosis of any dehydration (p < 0.001). The DHAKA score had a sensitivity of 86% and specificity of 54% for diagnosing severe dehydration and 93 and 50% for diagnosing any dehydration.ConclusionThe DHAKA score is now the first dehydration assessment tool both derived and validated in resource‐limited settings, and it outperformed the WHO algorithm. Frontline providers may use this new tool to better manage acute diarrhea in children.DHAKA score.image