bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolism of mineral‐sorbed organic matter and microbial lifestyles in fluvial ecosystems
Authors: Hunter William Ross , Niederdorfer Robert , Gernand Anna , Veuger Bart , Prommer Judith , Mooshammer Maria , Wanek Wolfgang , Battin Tom J 
Published: January 2016

AbstractIn fluvial ecosystems mineral erosion, carbon (C), and nitrogen (N) fluxes are linked via organomineral complexation, where dissolved organic molecules bind to mineral surfaces. Biofilms and suspended aggregates represent major aquatic microbial lifestyles whose relative importance changes predictably through fluvial networks. We tested how organomineral sorption affects aquatic microbial metabolism, using organomineral particles containing a mix of 13C, 15N‐labeled amino acids. We traced 13C and 15N retention within biofilm and suspended aggregate biomass and its mineralization. Organomineral complexation restricted C and N retention within biofilms and aggregates and also their mineralization. This reduced the efficiency with which biofilms mineralize C and N by 30% and 6%. By contrast, organominerals reduced the C and N mineralization efficiency of suspended aggregates by 41% and 93%. Our findings show how organomineral complexation affects microbial C:N stoichiometry, potentially altering the biogeochemical fate of C and N within fluvial ecosystems.
Dendritenfreie elektrochemische Abscheidung von nanokristallinem Zink aus einer Nickeltriflat‐haltigen ionischen Flüssigkeit für wiederaufladbare Zn‐Batterien
Authors: Liu Zhen , Cui Tong , Pulletikurthi Giridhar , Lahiri Abhishek , Carstens Timo , Olschewski Mark , Endres Frank 
Published: January 2016

AbstractMetallisches Zink ist ein vielversprechendes Anodenmaterial für wiederaufladbare Zn‐Batterien, allerdings verhindert das Dendritenwachstum von Zink bisher eine praktische Verwendung. Hier wird gezeigt, dass man nanokristallines Zink durch Versetzen mit Nickeltriflat als Additiv aus einer Zinktriflat enthaltenden ionischen Flüssigkeit dendritenfrei abscheiden kann. Die Bildung einer dünnen Schicht aus einer Zn‐Ni‐Legierung (η‐Phase und γ‐Phase) auf der Elektrodenoberfläche während der ersten Stadien der Abscheidung und die Entstehung von Grenzflächenschichten beeinflussen stark die Keimbildung und das Wachstum des Zinks. Eine einheitliche und nanokristalline Zinkabscheidung mit Partikelgrößen von ca. 25 nm wird in Gegenwart von NiII erzielt. Außerdem wird deutlich, dass dieses nanokristalline Zink eine hohe Zyklenstabilität (50 Abscheide‐/Auflösezyklen) aufweist. Das Konzept, den Elektrolyten, also die ionische Flüssigkeit, mit einem anorganischen Salz zu versetzen, erweist sich für das dendritenfreie Wachstum von Zink als zielführend.
Study of the binding and energy transfer of erbium ion with rhaponticin and its pharmacokinetics application
Authors: Sun Yang , Wang Wanqiang , Cheng Hua , Jiang Xiangsheng , Wu Junjun 
Published: January 2016

AbstractBinding and energy transfer of an erbium ion with rhaponticin (RH) was investigated and a simple spectrofluorimetric method was developed for determination of RH using an Er3+ probe. Results using spectra, chromatography and density functional theory (DFT) indicated that binding of Er3+ to RH occurred at the hydroxyl group of C‐11 and at the methoxy group at C‐12 of the conjugated aromatic ring through hydrogen bonding. Resonance energy transfer (RET) occurred from intramolecular charge transfers (ICT), the binding of RH to Er3+ ion induced fluorescence enhancement (FE) of the Er3+ ion. This method was applied to the pharmacokinetic detection of RH. The main advantages of the proposed method compared with previously reported ones are its simplicity and lower cost. Copyright © 2016 John Wiley & Sons, Ltd.
Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults
Authors: Humes D J , Walker A J , Hunt B J , Sultan A A , Ludvigsson J F , West J 
Published: January 2016

Abstract

Background
Appendicectomy is the commonest intra-abdominal emergency surgical procedure, and little is known regarding the magnitude and timing of the risk of venous thromboembolism (VTE) after surgery. This study aimed to determine absolute and relative rates of symptomatic VTE following emergency appendicectomy.

Methods
A cohort study was undertaken using linked primary (Clinical Practice Research Datalink) and secondary (Hospital Episode Statistics) care data of patients who had undergone emergency appendicectomy from 2001 to 2011. Crude rates and adjusted incidence rate ratios (IRRs) for VTE were calculated using Poisson regression, compared with baseline risk in the year before appendicectomy.

Results
A total of 13 441 patients were identified, of whom 56 (0·4 per cent) had a VTE in the first year after surgery. The absolute rate of VTE was highest during the in-hospital period, with a rate of 91·29 per 1000 person-years, which was greatest in those with a length of stay of 7 days or more (267·12 per 1000 person-years). This risk remained high after discharge, with a 19·1- and 6·6-fold increased risk of VTE in the first and second months respectively after discharge, compared with the year before appendicectomy (adjusted IRR: month 1, 19·09 (95 per cent c.i. 9·56 to 38·12); month 2, 6·56 (2·62 to 16·44)).

Conclusion
The risk of symptomatic VTE following appendicectomy is relatively high during the in-hospital admission and remains increased after discharge. Trials of extended thromboprophylaxis are warranted in patients at particularly high risk.
Fully automated open‐source lesion mapping of T2‐FLAIR images with FSL correlates with clinical disability in MS
Authors: Wetter Nathan C. , Hubbard Elizabeth A. , Motl Robert W. , Sutton Bradley P. 
Published: January 2016

AbstractBackgroundT2 Lesion Volume (T2LV) has been an important biomarker for multiple sclerosis (MS). Current methods available to quantify lesions from MR images generally require manual adjustments or multiple images with different contrasts. Further, implementations are often not easily or openly accessible.ObjectiveWe created a fully unsupervised, single T2 FLAIR image T2LV quantification package based on the popular open‐source imaging toolkit FSL.MethodsBy scripting various processing tools in FSL, we developed an image processing pipeline that distinguishes normal brain tissue from CSF and lesions. We validated our method by hierarchical multiple regression (HMR) with a preliminary study to see if our T2LVs correlate with clinical disability measures in MS when controlled for other variables.ResultsPearson correlations between T2LV and Expanded Disability Status Scale (EDSS: r = 0.344, P = 0.013), Six‐Minute Walk (6MW: r = −0.513, P = 0.000), Timed 25‐Foot Walk (T25FW: r = −0.438, P = .000), and Symbol Digit Modalities Test (SDMT: r = −0.499, P = 0.000) were all significant. Partial correlations controlling for age were significant between T2LV and 6MW (r = −0.433, P = 0.002), T25FW (r = −0.392, P = 0.004), and SDMT (r = −0.450, P = 0.001). In HMR, T2LV explained significant additional variance in 6MW (R2 change = 0.082, P = 0.020), after controlling for confounding variables such as age, white matter volume (WMV), and gray matter volume (GMV).ConclusionOur T2LV quantification software produces T2LVs from a single FLAIR image that correlate with physical disability in MS and is freely available as open‐source software.
A prospective ascertainment of cancer incidence in sub‐Saharan Africa: The case of Kaposi sarcoma
Authors: Semeere Aggrey , Wenger Megan , Busakhala Naftali , Buziba Nathan , Bwana Mwebesa , Muyindike Winnie , Amerson Erin , Maurer Toby , McCalmont Timothy , LeBoit Philip , Musick Beverly , Yiannoutsos Constantin , Lukande Robert , Castelnuovo Barbara , Laker‐Oketta Miriam , Kambugu Andrew , Glidden David , Wools‐Kaloustian Kara , Martin Jeffrey 
Published: January 2016

AbstractIn resource‐limited areas, such as sub‐Saharan Africa, problems in accurate cancer case ascertainment and enumeration of the at‐risk population make it difficult to estimate cancer incidence. We took advantage of a large well‐enumerated healthcare system to estimate the incidence of Kaposi sarcoma (KS), a cancer which has become prominent in the HIV era and whose incidence may be changing with the rollout of antiretroviral therapy (ART). To achieve this, we evaluated HIV‐infected adults receiving care between 2007 and 2012 at any of three medical centers in Kenya and Uganda that participate in the East Africa International Epidemiologic Databases to Evaluate AIDS (IeDEA) Consortium. Through IeDEA, clinicians received training in KS recognition and biopsy equipment. We found that the overall prevalence of KS among 102,945 HIV‐infected adults upon clinic enrollment was 1.4%; it declined over time at the largest site. Among 140,552 patients followed for 319,632 person‐years, the age‐standardized incidence rate was 334/100,000 person‐years (95% CI: 314–354/100,000 person‐years). Incidence decreased over time and was lower in women, persons on ART, and those with higher CD4 counts. The incidence rate among patients on ART with a CD4 count >350 cells/mm3 was 32/100,000 person‐years (95% CI: 14–70/100,000 person‐years). Despite reductions over time coincident with the expansion of ART, KS incidence among HIV‐infected adults in East Africa equals or exceeds the most common cancers in resource‐replete settings. In resource‐limited settings, strategic efforts to improve cancer diagnosis in combination with already well‐enumerated at‐risk denominators can make healthcare systems attractive platforms for estimating cancer incidence.
The effects of hemoglobin levels and their interactions with cigarette smoking on survival in nasopharyngeal carcinoma patients
Authors: Zeng Qi , Shen Lu‐Jun , Li Sheng , Chen Ling , Guo Xiang , Qian Chao‐Nan , Wu Pei‐Hong 
Published: January 2016

AbstractThere is very little published information regarding the prognostic value of hemoglobin (Hb) levels combined with smoking on the survival of patients with nasopharyngeal carcinoma (NPC), and the interactions between them remain unclear. A total of 2440 NPC patients were confirmed, and multivariate analysis was performed to identify valuable prognostic Hb levels in the entire population and in the cohort of smokers. The survival differences were compared using log‐rank tests. The multiplicative and additive interactions were assessed using Cox regression and a Microsoft Word Excel spreadsheet. Postradiotherapy (RT) Hb was an independent prognostic factor for overall survival (OS) (HR = 0.797; P = 0.006), failure‐free survival (FFS) (HR=0.811; P = 0.010), and loco‐regional failure‐free survival (LR‐FFS) (HR = 0.725; P = 0.000). In the cohort of smokers, pack‐years was also an independent predictor of OS (HR = 0.673; P < 0.001) and FFS (HR = 0.681; P < 0.001), LR‐FFS (HR = 0.663; P = 0.001). A significant positive additive effect was found for the interaction between low post‐RT Hb and high SI on OS, with RERI = 5.616, AP = 0.665, and S = 4.078. Stratified analyses demonstrated that heavy smokers with low post‐RT Hb had HRs of 2.295 (P < 0.001) for death, 2.222 (P < 0.001) for disease failure, and 2.267 (P < 0.001) loco‐regional recurrence compared with light smokers with high post‐RT Hb levels, and post‐RT Hb level is an important predictor of survival in patients with NPC. The positive interaction between post‐RT Hb level and pack‐years contributes to the elevated risk of poor survival. Oncologists should devote particular attention to heavy smokers with low post‐RT Hb levels in the future.
Confirmation of a Protein–Protein Interaction in the Pantothenate Biosynthetic Pathway by Using Sortase‐Mediated Labelling
Authors: Morrison Philip M. , Balmforth Matthew R. , Ness Samuel W. , Williamson Daniel J. , Rugen Michael D. , Turnbull W. Bruce , Webb Michael E. 
Published: January 2016

AbstractHigh‐throughput studies have been widely used to identify protein–protein interactions; however, few of these candidate interactions have been confirmed in vitro. We have used a combination of isothermal titration calorimetry and fluorescence anisotropy to screen candidate interactions within the pantothenate biosynthetic pathway. In particular, we observed no interaction between the next enzyme in the pathway, pantothenate synthetase (PS), and aspartate decarboxylase, but did observe an interaction between PS and the putative Nudix hydrolase, YfcD. Confirmation of the interaction by fluorescence anisotropy was dependent upon labelling an adventitiously formed glycine on the protein N‐terminal affinity purification tag by using Sortase. Subsequent formation of the protein–protein complex led to apparent restriction of the dynamics of this tag, thus suggesting that this approach could be generally applied to a subset of other protein–protein interaction complexes.
Partial Blockage of the Reversible Solid‐Solid Transition of Strontium Succinate
Authors: Couvrat Nicolas , Martins Damien , Lafontaine Anaïs , Sanselme Morgane , Dupray Valérie , Taulelle Pascal , Lerestif Jean‐Michel , Lynch Michael , Vaysse‐Ludot Lucile , Coquerel Gérard 
Published: January 2016

AbstractStrontium succinate, an active pharmaceutical ingredient against osteoporosis, exhibits two polymorphs related by a reversible order‐disorder transformation at about 50 °C. However, during the industrial crystallization process, the transition from the high‐temperature form towards the low‐temperature form was partially inhibited, leading to a mixture of phases at room temperature. The stressful character of the industrial process as demonstrated by in situ X‐ray diffraction and Raman analyses led to defects, constraints, and a coarse mosaicity within crystals. Moreover, thermogravimetric analyses revealed that a non‐negligible amount of water was trapped inside the crystalline solid. The combination of these two factors (stressful crystallization and trapped water) could be at the origin of the partial blockage of the transition.
Electrochemical Study of Oxygen Reduction on a Carbon‐Supported Core–Shell Platinum–Gold Electrocatalyst with Tuneable Gold Surface Composition
Authors: Mahesh Ijjada , Sarkar A. 
Published: January 2016

AbstractThe presence of gold on the surface of platinum nanoparticles can have profound effects on the activity in the electrochemical oxygen reduction reaction (ORR). In this work, the ORR activity is studied at different surface coverage of gold on two types of core–shell platinum–gold catalysts. Surface‐limited redox reaction and redox transmetalation methods are used to synthesize core–shell catalysts with varying degrees of gold coverage on their surface. Experimental results indicate that the presence of gold on the surface intrinsically decreases the ORR activity. Furthermore, the effect of the core on the activity for ORR has been studied.
Discrimination of mushroom disease‐related mould species based solely on unprocessed chromatograms
Authors: Radványi Dalma , Gere Attila , Sipos László , Kovács Sándor , Jókai Zsuzsa , Fodor Péter 
Published: January 2016

AbstractAgaricus bisporus A15 species (bisporic button mushroom) and its two main mould diseases (Mycogone perniciosa and Trichoderma aggressivum) were analysed using headspace solid‐phase microextraction sampling coupled with gas chromatograpy–mass spectrometry analysis. The presence or absence of mushroom disease‐related moulds can easily be detected and monitored in the air by headspace solid‐phase microextraction gas chromatograpy–mass spectrometry via their emitted microbial volatile organic compounds. Detrended fluctuation analysis (DFA) was first applied to distinguish different mould samples based on their unprocessed total ion chromatograms, which describe the air polluted by microbial volatile organic compounds. A two‐dimensional plot, generated from the results of DFA, visualizes the relationship of the analysed samples. The pattern found by DFA was compared with the pattern found by the traditionally applied principal component analysis. Cluster analysis (using Euclidean distance and Ward's method) of the principal component analysis scores and DFA coefficients showed characteristic groupings. A methodology is introduced, which uses the unprocessed chromatogram, without any time‐consuming feature extraction and can indicate the presence of infected samples. The proposed methodology is able to give a support to the mushroom growers to indicate different mushroom disease‐related infection via air monitoring. Additionally, DFA is a sample‐independent and universal method. Hence, it can be also applied to distinguish unprocessed chromatograms produced by any other analytical equipment. Copyright © 2016 John Wiley & Sons, Ltd.
ChemInform Abstract: Enhancement of the Thermoelectric Properties of MnSb2Se4 Through Cu Resonant Doping.
Authors: Zhao Huaizhou , et al.  
Published: January 2016

AbstractSingle phases of Mn1‐xCuxSb2Se4 (x = 0‐0.35) thermoelectric materials are prepared by heating stoichiometric mixtures of the elements (evacuated quartz tubes, 1.
ChemInform Abstract: Single Crystal Growth, Structural Characteristics and Magnetic Properties of Chromium Substituted M‐Type Ferrites.
Authors: Niewa Rainer , et al.  
Published: January 2016

AbstractSingle crystals of SrFe12‐xCrxO19 (I) and BaFe12‐xCrxO19 (II) ferrites are grown using two different fluxes, Na2CO3 (30 wt%) and mixtures of SrCl2 and BaCl2, further containing Fe2O3, Cr2O3, and BaCO3 (Pt crucible, 1260 °C, 3 h or 1310 °C, 40 h, resp.).
ChemInform Abstract: BiOI Solar Cells.
Authors: Sfaelou S. , Raptis D. , Dracopoulos V. , Lianos P. 
Published: January 2016

AbstractBiOI nanoflakes combined with a thin nanoparticulate TiO2 layer form a visible‐light responsive photoanode, which can be employed with a liquid electrolyte solar cell.
ChemInform Abstract: “Water‐in‐Salt” Electrolyte Enables High‐Voltage Aqueous Lithium‐Ion Chemistries.
Authors: Suo Liumin , Borodin Oleg , Gao Tao , Olguin Marco , Ho Janet , Fan Xiulin , Luo Chao , Wang Chunsheng , Xu Kang 
Published: January 2016

AbstractHighly concentrated aqueous solutions of LiN(SO2CF3)2 (5—20 M at 25 °C) are used as an electrolyte in a CR2032‐type coin cell containing either LiMn2O4 or LiNi0.8Co0.15Al0.05O2 as the cathode and Cu‐leached Mo6S8 Chevrel phase as the anode separated by glass fiber fabrics.
ChemInform Abstract: Electrochemical Oxidation of 243Am(III) in Nitric Acid by a Terpyridyl‐Derivatized Electrode.
Authors: Dares Christopher J. , Lapides Alexander M. , Mincher Bruce J. , Meyer Thomas J. 
Published: January 2016

AbstractA high‐surface area, tin‐doped indium oxide electrode surface‐derivatized with a terpyridine ligand is used to oxidize Am(III) to Am(IV) and Am(VI) in nitric acid.
ChemInform Abstract: Perovskites with the Framework‐Forming Xenon.
Authors: Britvin Sergey N. , Kashtanov Sergei A. , Krzhizhanovskaya Maria G. , Gurinov Andrey A. , Glumov Oleg V. , Strekopytov Stanislav , Kretser Yury L. , Zaitsev Anatoly N. , Chukanov Nikita V. , Krivovichev Sergey V. 
Published: January 2016

AbstractThe new double‐perovskites KM(XeNaO6) (M: Ca, Sr, Ba) are obtained from the hydrothermal reactions of equimolar amounts of alkaline earth nitrates and Na4XeO6 in strong alkaline solution (10N KOH, autoclave, 170 °C, 24 h).
ChemInform Abstract: The Catalytic Asymmetric Synthesis of Tetrahydropyridazines via Inverse Electron‐Demand Aza‐Diels—Alder Reaction of Enol Ethers with Azoalkenes.
Authors: Wei Liang , Wang Chun‐Jiang 
Published: January 2016

AbstractThe scalable reaction provides the products in high yields and with high enantiomeric excesses.
ChemInform Abstract: Phosphido‐ and Amidozirconocene Cation‐Based Frustrated Lewis Pair Chemistry.
Authors: Normand Adrien T. , Daniliuc Constantin G. , Wibbeling Birgit , Kehr Gerald , Le Gendre Pierre , Erker Gerhard 
Published: January 2016

AbstractNovel cationic Zr phosphido and amido complexes catalyze the hydrogenation of electron‐rich olefins and alkynes under mild conditions.
ChemInform Abstract: Amination of ω‐Functionalized Aliphatic Primary Alcohols by a Biocatalytic Oxidation—Transamination Cascade.
Authors: Pickl Mathias , Fuchs Michael , Glueck Silvia M. , Faber Kurt 
Published: January 2016

AbstractA five‐enzyme cascade for the amination of primary alcohols by coupling a long‐chain alcohol oxidase with an ω‐transaminase is successfully extended to also encompass nonactivated fatty alcohols as substrates.
ChemInform Abstract: Nucleophilic Iododifluoromethylation of Aldehydes Using Bromine/Iodine Exchange.
Authors: Levin Vitalij V. , Smirnov Vladimir O. , Struchkova Marina I. , Dilman Alexander D. 
Published: January 2016

AbstractA method for the iododifluoromethylation of aldehydes using (bromodifluoromethyl)trimethylsilane is described.
ChemInform Abstract: Transition‐Metal‐Free Synthesis of Polysubstituted Cyclopropane Derivatives from N‐Tosylhydrazones and Their Cytotoxic Activities.
Authors: Lawson Marie , Bignon Jerome , Brion Jean‐Daniel , Hamze Abdallah , Alami Mouad 
Published: January 2016

AbstractThe isoCA4 analogue (XII) is found to exhibit good antiproliferative activity against HCT116 cells.
ChemInform Abstract: Acetoxy‐Substituted Cyclopropane Dicarbonyls as Stable Donor—Acceptor—Acceptor Cyclopropanes.
Authors: Reyes Yahaira , Mead Keith T. 
Published: January 2016

AbstractThe rhodium‐catalyzed reaction of aryl‐substituted α‐diazo‐β‐keto esters with vinyl acetate is shown to form acyloxy‐substituted donor‐acceptor‐acceptor cyclopropanes, and depending on the aryl substituent the products are obtained in low to high yields.
ChemInform Abstract: Alkynylation of Tertiary Cycloalkanols via Radical C—C Bond Cleavage: A Route to Distal Alkynylated Ketones.
Authors: Wang Shun , Guo Li‐Na , Wang Hua , Duan Xin‐Hua 
Published: January 2016

AbstractThe tandem alkynylation/ring opening reaction of cyclobutanols (I) and (VII) with hypervalent iodide compound (II) proceeds readily in the presence of Na2S2O8 to afford alkynylated ketones (III) and (VIII), respectively.
ChemInform Abstract: Visible Light Mediated Reductive Cleavage of C—O Bonds Accessing α‐Substituted Aryl Ketones.
Authors: Speckmeier Elisabeth , Padie Clement , Zeitler Kirsten 
Published: January 2016

AbstractA mild and effective method for the photocatalytic deoxygenation of simple O‐acrylbenzoin and ‐acyloin derivatives is developed.
ChemInform Abstract: ZrO2 Nanoparticles as a Reusable Solid Dual Acid—Base Catalyst for Facile One‐Pot Synthesis of Multi‐Functionalized Spirooxindole Derivatives under Solvent Free Condition.
Authors: Bodhak Chandan , Kundu Ashis , Pramanik Animesh 
Published: January 2016

AbstractA convenient and eco‐friendly method for the simple two‐step one‐pot synthesis of the title compounds from isatins, malononitrile, cyclohexane 1,3‐diones/pyrazoles is developed.
ChemInform Abstract: Synthesis of Functionalized Tryptamines by Broensted Acid Catalyzed Cascade Reactions.
Authors: Melis Nicola , Secci Francesco , Boddaert Thomas , Aitken David J. , Frongia Angelo 
Published: January 2016

AbstractSolvent‐free PTSA‐catalyzed reaction between 2‐hydroxycyclobutanone and N‐alkylanilines gives tryptamine derivatives in low to good yields.
ChemInform Abstract: Efficient Pd‐Catalyzed Domino Synthesis of 1‐Phenyl‐1H‐indol‐2‐amine and 5‐Amino‐indolo[1,2‐a]quinazoline Derivatives.
Authors: Jiang Min , Xiang Haoyue , Zhu Fangxia , Xu Xing , Deng Lianfu , Yang Chunhao 
Published: January 2016

AbstractThe title compounds are prepared from 2‐bromophenylmalononitriles and anilines via Buchwald—Hartwig coupling and base‐promoted intramolecular nucleophilic reaction.
ChemInform Abstract: One‐Pot Three‐Component Route for the Synthesis of Rhodanine Derivatives in Water.
Authors: Ziyaei Halimehjani Azim , Hosseinkhany Samaneh 
Published: January 2016

AbstractVarious rhodanine derivatives are efficiently and environmentally friendly synthesized from primary amines, carbon disulfide, and maleic anhydride by a sequential Michael addition‐intramolecular amide bond formation.