bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fluorene‐containing cardo and fully aromatic single ion conducting polymer electrolyte for room temperature, high performance lithium ion batteries
Authors: Zhang Yunfeng , Liu Yuan , Liu Xupo , Li Cuicui , Dong Jiaming , Sun Yubao , Zeng Danli , Yang Zehui , Cheng Hansong 
Published: September 2017

AbstractThe self‐assembly process between rigid fully aromatic single ion conducting polymer electrolytes (SIPEs) and flexible aliphatic binder for fabrication of macro‐scale porosity of membrane for enhancement of ionic conductivity has been demonstrated in our previous works. In this article, the bulky and rigid fluorene cardo groups are successfully introduced into the fully aromatic polymeric backbone to synthesize the fluorene‐containing cardo fully aromatic single ion conducting polymer electrolyte (fca‐SIPE). The synthesized fca‐SIPE is then blended with a flexible aliphatic PVDF‐HFP binder to prepare fca‐SIPE membrane via a solution cast method. By comparing with results of the previous works, in this case, not only the macro‐scale porous morphology derived from the self‐assembly process between PVDF‐HFP and fca‐SIPE, but also the interior nano‐scale lithium ion transport pathway throughout the free volume formed by the fluorene groups is obtained. The effect of the fluorene group on the key properties of membrane, such as ionic conductivity and battery performance, is systematically investigated. The excellent performance at high C‐rates at room temperature is demonstrated.
An Efficient Synthesis of 2,4,5‐Trisubstituted and 1,2,4,5‐Tetrasubstituted Imidazoles Using Dihydroquinolines as Novel Organocatalyst
Authors: Waheed Mohammed , Ahmed Naseem , A Alsharif Meshari , Alahmdi Mohammed Issa , Mukhtar Sayeed 
Published: September 2017

AbstractA simple, and environmentally benign synthesis of 2,4,5‐trisubstituted and 1,2,4,5‐tetrasubstituted imidazoles has been successfully accomplished via multi‐component cyclo‐condensation of 1,2‐dicarbonyl, aldehyde, and ammonium acetate and aniline respectively, using dihydroquinoline based novel organocatalysts at refluxed temperature in ethanol. High yields (94 %), easy work‐up and purification of products without column chromatography are the key advantages of the method.
Stretchable Electronic Sensors of Nanocomposite Network Films for Ultrasensitive Chemical Vapor Sensing
Authors: Yan Hong , Zhong Mengjuan , Lv Ze , Wan Pengbo 
Published: September 2017

AbstractA stretchable, transparent, and body‐attachable chemical sensor is assembled from the stretchable nanocomposite network film for ultrasensitive chemical vapor sensing. The stretchable nanocomposite network film is fabricated by in situ preparation of polyaniline/MoS2 (PANI/MoS2) nanocomposite in MoS2 suspension and simultaneously nanocomposite deposition onto prestrain elastomeric polydimethylsiloxane substrate. The assembled stretchable electronic sensor demonstrates ultrasensitive sensing performance as low as 50 ppb, robust sensing stability, and reliable stretchability for high‐performance chemical vapor sensing. The ultrasensitive sensing performance of the stretchable electronic sensors could be ascribed to the synergistic sensing advantages of MoS2 and PANI, higher specific surface area, the reliable sensing channels of interconnected network, and the effectively exposed sensing materials. It is expected to hold great promise for assembling various flexible stretchable chemical vapor sensors with ultrasensitive sensing performance, superior sensing stability, reliable stretchability, and robust portability to be potentially integrated into wearable electronics for real‐time monitoring of environment safety and human healthcare.
Encapsulated Vanadium‐Based Hybrids in Amorphous N‐Doped Carbon Matrix as Anode Materials for Lithium‐Ion Batteries
Authors: Long Bei , Balogun Muhammad‐Sadeeq , Luo Lei , Luo Yang , Qiu Weitao , Song Shuqin , Zhang Lei , Tong Yexiang 
Published: September 2017

AbstractRecently, researchers have made significant advancement in employing transition metal compound hybrids as anode material for lithium‐ion batteries and developing simple preparation of these hybrids. To this end, this study reports a facile and scalable method for fabricating a vanadium oxide–nitride composite encapsulated in amorphous carbon matrix by simply mixing ammonium metavanadate and melamine as anode materials for lithium‐ion batteries. By tuning the annealing temperature of the mixture, different hybrids of vanadium oxide–nitride compounds are synthesized. The electrode material prepared at 700 °C, i.e., VM‐700, exhibits excellent cyclic stability retaining 92% of its reversible capacity after 200 cycles at a current density of 0.5 A g−1 and attractive rate performance (220 mAh g−1) under the current density of up to 2 A g−1. The outstanding electrochemical properties can be attributed to the synergistic effect from heterojunction form by the vanadium compound hybrids, the improved ability of the excellent conductive carbon for electron transfer, and restraining the expansion and aggregation of vanadium oxide–nitride in cycling. These interesting findings will provide a reference for the preparation of transition metal oxide and nitride composites as well.
Multicolor Photo‐Crosslinkable AIEgens toward Compact Nanodots for Subcellular Imaging and STED Nanoscopy
Authors: Fang Xiaofeng , Chen Xuanze , Li Rongqin , Liu Zhihe , Chen Haobin , Sun Zezhou , Ju Bo , Liu Yifei , Zhang Sean Xiao‐An , Ding Dan , Sun Yujie , Wu Changfeng 
Published: September 2017

AbstractAggregation induced emission (AIE) has attracted considerable interest for the development of fluorescence probes. However, controlling the bioconjugation and cellular labeling of AIE dots is a challenging problem. Here, this study reports a general approach for preparing small and bioconjugated AIE dots for specific labeling of cellular targets. The strategy is based on the synthesis of oxetane‐substituted AIEgens to generate compact and ultrastable AIE dots via photo‐crosslinking. A small amount of polymer enriched with oxetane groups is cocondensed with most of the AIEgens to functionalize the nanodot surface for subsequent streptavidin bioconjugation. Due to their small sizes, good stability, and surface functionalization, the cell‐surface markers and subcellular structures are specifically labeled by the AIE dot bioconjugates. Remarkably, stimulated emission depletion imaging with AIE dots is achieved for the first time, and the spatial resolution is significantly enhanced to ≈95 nm. This study provides a general approach for small functional molecules for preparing small sized and ultrastable nanodots.
The connections between group maturity, software development velocity, and planning effectiveness
Authors: Al‐Sabbagh Khaled Walid , Gren Lucas 
Published: September 2017

AbstractEmpirical evidence regarding the connection between group development (maturity) and the success of software development teams is lacking. The purpose of this research is to gain a qualitative and quantitative understanding of how velocity and planning effectiveness of software teams connect to a group development model. The Group Development Questionnaire was given to 19 software developers from 4 work groups to assess their group development maturity. The work groups' responses to the survey were checked for correlation with development velocity and planning effectiveness. Semistructured interviews were conducted with 16 individuals from the same 4 work groups to explore issues about their group maturity and to validate the responses of the interviewees in the Group Development Questionnaire. The measurement of the fourth stage of group development had a strong association with the planning effectiveness measurement, which means that a team with less issues in the fourth phase of group development is more effective in adhering to its plans. On the other hand, group development and velocity showed no significant convergent validity. We conclude that the dynamics within software development teams might correlate to their ability to deliver the expected outcome as planned but not to their ability to develop tasks faster.
Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton’s Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase
Authors: Bustos Francisco , Sepúlveda Hugo , Prieto Catalina P. , Carrasco Margarita , Díaz Lorena , Palma José , Lattus José , Montecino Martín , Palma Verónica 
Published: September 2017

Abstract
Novel bone regeneration approaches aim to obtain immature osteoblasts from somatic stem cells. Umbilical cord Wharton’s jelly mesenchymal stem cells (WJ-MSCs) are an ideal source for cell therapy. Hence, the study of mechanisms involved in WJ-MSC osteoblastic differentiation is crucial to exploit their developmental capacity. Here, we have assessed epigenetic control of the Runt-related transcription factor 2 (RUNX2) osteogenic master regulator gene in WJ-MSC. We present evidence indicating that modulation of RUNX2 expression through preventing Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase activity is relevant to enhance WJ-MSC osteoblastic potential. Hence, JARID1B loss of function in WJ-MSC results in increased RUNX2/p57 expression. Our data highlight JARID1B activity as a novel target to modulate WJ-MSC osteoblastic differentiation with potential applications in bone tissue engineering.
Bone marrow‐derived multipotent mesenchymal stromal cells from horses after euthanasia
Authors: Schröck Carmen , Eydt Carina , Geburek Florian , Kaiser Lena , Päbst Felicitas , Burk Janina , Pfarrer Christiane , Staszyk Carsten 
Published: September 2017

AbstractAllogeneic equine multipotent mesenchymal stromal cells (eMSCs) have been proposed for use in regenerative therapies in veterinary medicine. A source of allogeneic eMSCs might be the bone marrow from euthanized horses. The purpose of this study was to compare in vitro characteristics of equine bone marrow derived eMSC (eBM‐MSCs) from euthanized horses (eut‐MSCs) and from narcotized horses (nar‐MSCs). Eut‐MSCs and nar‐MSCs showed typical eMSC marker profiles (positive: CD44, CD90; negative: CD11a/CD18 and MHCII) and possessed tri‐lineage differentiation characteristics. Although CD105 and MHCI expression varied, no differences were detected between eut‐MSCs and nar‐MSCs. Proliferation characteristics did not differ between eut‐MSCs and nar‐MSCs, but age dependent decrease in proliferation and increase in MHCI expression was detected. These results suggest the possible use of eut‐MSCs for therapeutic applications and production of commercial available eBM‐MSC products.
Critical appraisal of genotype assessment in molybdenum cofactor deficiency
Authors: Hinderhofer Katrin , Mechler Konstantin , Hoffmann Georg F. , Lampert Anette , Mountford William K. , Ries Markus 
Published: September 2017

AbstractIntroductionMolybdenum cofactor deficiency (MoCD) is an ultra‐orphan, life‐threatening disease. Substrate substitution therapy has successfully been performed in single cases of MoCD type A and clinical trials are underway for drug registration. We present an innovative approach for classification of genotype severity to test the hypothesis that milder sequence variants in MoCD result in a less severe disease phenotype quantitated by patient survival.MethodsAll available worldwide published cases with clinical and genetic data were included (n = 40). We stratified the already published disease causing sequence variants as mild or severe with the use of in silico prediction programs, where possible and assessed the possible impact of the variants on the expression of the gene or function of the expressed protein. In a compound heterozygous situation the mildest sequence variant determined the genotype. Subsequently, clinical manifestations and outcomes of both groups were compared.ResultsPatients with a severe genotype showed a median survival of 15 months and had a lower probability of survival compared to patients with mild genotypes who were all alive at last reported follow‐up (p = 0.0203, Log‐rank test).DiscussionThe severity of the genotype assessed by in silico prediction and further classification explained survival in molybdenum cofactor deficiency and may therefore be considered a confounder for the outcome of therapeutic clinical trials requiring adjustment in the clinical trial design or analysis. These results should further be investigated by future in vitro or in vivo functional studies. Caution should be taken with this approach for the classification of variants in molecular genetic diagnostics or genetic counseling.
Species diversity of herbivorous insects: a brief review to bridge the gap between theories focusing on the generation and maintenance of diversity
Authors: Nakadai Ryosuke 
Published: September 2017

AbstractHerbivorous insects are remarkably species‐diverse, and the cause of such diversity remains a classical issue in the fields of ecology and evolution. The traditional explanation for the huge diversity of such insects is that repeated dietary changes over evolutionary time provided opportunities for speciation, thereby enhancing the diversification rate. A different view suggests that herbivore diversity became saturated over time, with factors affecting the points of dynamic equilibrium of species diversity within each lineage (and thus associated with maintenance of species diversity) being the determinants of the diversity evident today. Thus, both generation and maintenance processes, and their relative importance, are critical for understanding the diversity of herbivorous insects. Furthermore, the neutral theory of biodiversity and biogeography has recently gained attention as an alternative explanation for the generation and maintenance of diversity, as opposed to adaptive processes centred around host specificity. However, these possible routes toward herbivore diversity have rarely been evaluated in parallel, and the work of various groups has become both segmentalised and complicated, compromising any comprehensive understanding of the issue. Thus, in the present paper, I briefly review our knowledge of herbivore diversity and the major relevant studies. The aim was to share knowledge, creating a common starting point from which future discussions among researchers may be generated. It may be that no single approach can resolve the many remaining questions on herbivore diversity. However, an improved understanding of such diversity can be achieved by combining knowledge gained in studies of both the generation and maintenance of diversity.
Remote Sensing of Chaco Roads Revisited
Authors: Friedman Richard A. , Sofaer Anna , Weiner Robert S. 
Published: September 2017

ABSTRACTThis paper reports on the first and highly effective use of Light Detection and Ranging (lidar) technology to document Chaco roads, monumental linear surface constructions of the precolumbian culture that occupied the Four Corners region of the American Southwest between approximately AD 600 and 1300. Analysis of aerial photographs supplemented by ground survey has been the traditional methodology employed to identify Chaco roads, but their traces have become increasingly subtle and difficult to detect in recent years due to the impacts of natural weathering, erosion, and land development. Roads that were easily visible in aerial photography and on the ground in the 1980s are now virtually invisible, underscoring the need for new, cutting-edge techniques to detect and document them. Using three case studies of the Aztec Airport Mesa Road, the Great North Road, and the Pueblo Alto Landscape, we demonstrate lidar's unprecedented ability to document known Chaco roads, discover previously undetected road segments, and produce a precise quantitative record of these rapidly vanishing features.
Preliminary Results for Estimating the Bone Background Uncertainties at SUERC Using Statistical Analysis
Authors: Naysmith P , Dunbar E , Scott E M , Cook G T , Tripney B G 
Published: September 2017

AbstractBone is frequently dated in archaeological studies and, especially for very old bones (more than 40,000 years old), it is critical to have an accurate and precise measure of the material-specific background value and its associated uncertainty. The SUERC Radiocarbon Laboratory has obtained a mammoth bone as a background bone standard and an appropriate number are now routinely prepared and measured in each AMS batch, resulting in the accumulation of a large number of background bone results over a two-year period. Additionally, information on which of the two accelerator mass spectrometry (AMS) instruments was used to make the radiocarbon (14C) measurements, and which sample pretreatment method (modified Longin or modified ultrafiltration) was used to extract and purify the collagen, is recorded for each sample. These data have been used to estimate the laboratory bone background (to be subtracted from each unknown bone sample prepared in the laboratory) and its associated analytical uncertainty. The statistical analysis of the bone results has made use of a linear mixed effects model to examine the variation, and to apportion the overall variation between and within batches on both AMS instruments, and the different pretreatment methods used at SUERC.
Diminished medial prefrontal cortex activation during the recollection of stressful events is an acquired characteristic of PTSD
Authors: Dahlgren M. K. , Laifer L. M. , VanElzakker M. B. , Offringa R. , Hughes K. C. , Staples-Bradley L. K. , Dubois S. J. , Lasko N. B. , Hinojosa C. A. , Orr S. P. , Pitman R. K. , Shin L. M. 
Published: September 2017

AbstractBackgroundPrevious research has shown relatively diminished medial prefrontal cortex activation and heightened psychophysiological responses during the recollection of personal events in post-traumatic stress disorder (PTSD), but the origin of these abnormalities is unknown. Twin studies provide the opportunity to determine whether such abnormalities reflect familial vulnerabilities, result from trauma exposure, or are acquired characteristics of PTSD.MethodsIn this case–control twin study, 26 male identical twin pairs (12 PTSD; 14 non-PTSD) discordant for PTSD and combat exposure recalled and imagined trauma-unrelated stressful and neutral life events using a standard script-driven imagery paradigm during functional magnetic resonance imaging and concurrent skin conductance measurement.ResultsDiminished activation in the medial prefrontal cortex during Stressfulv.Neutral script-driven imagery was observed in the individuals with PTSD, relative to other groups.ConclusionsDiminished medial prefrontal cortex activation during Stressfulv.Neutral script-driven imagery may be an acquired characteristic of PTSD. If replicated, this finding could be used prospectively to inform diagnosis and the assessment of treatment response.
LEGITIMACY OF MEDICINES FUNDING IN THE ERA OF ACCELERATED ACCESS
Authors: Pace Jessica , Pearson Sallie-Anne , Lipworth Wendy 
Published: September 2017

Objectives: In recent years, numerous frameworks have been developed to enhance the legitimacy of health technology assessment processes. Despite efforts to implement these “legitimacy frameworks,” medicines funding decisions can still be perceived as lacking in legitimacy. We, therefore, sought to examine stakeholder views on factors that they think should be considered when making decisions about the funding of high-cost breast cancer therapies, focusing on those that are not included in current frameworks and processes.Methods: We analyzed published discourse on the funding of high-cost breast-cancer therapies. Relevant materials were identified by searching the databases Google, Google Scholar, and Factiva in August 2014 and July 2016 and these were analyzed thematically.Results: We analyzed fifty published materials and found that stakeholders, for the most part, want to be able to access medicines more quickly and at the same time as other patients and for decision makers to be more flexible with regards to evidence requirements and to use a wider range of criteria when evaluating therapies. Many also advocated for existing process to be accelerated or bypassed to improve access to therapies.Conclusions: Our results illustrate that a stakeholder-derived conceptualization of legitimacy emphasizes principles of accelerated access and is not fully accounted for by existing frameworks and processes aimed at promoting legitimacy. However, further research examining the ethical, political, and clinical implications of the stakeholder claims raised here is needed before firm policy recommendations can be made.
First Colombian Solar Radio Interferometer: current stage
Authors: Gómez J. C. Guevara , Oliveros J. C. Martínez , Calvo-Mozo B. 
Published: September 2017

AbstractSolar radio astronomy is a fast developing research field in Colombia. Here, we present the scientific goals, specifications and current state of the First Colombian Solar Radio Interferometer consisting of two log-periodic antennas covering a frequency bandwidth op to 800 MHz. We describe the importance and benefits of its development to the radioastronomy in Latin America and its impact on the scientific community and general public.
sTools – a data reduction pipeline for the GREGOR Fabry-Pérot Interferometer and the High-resolution Fast Imager at the GREGOR solar telescope
Authors: Kuckein C. , Denker C. , Verma M. , Balthasar H. , Manrique S. J. González , Louis R. E. , Diercke A. 
Published: September 2017

AbstractA huge amount of data has been acquired with the GREGOR Fabry-Pérot Interferometer (GFPI), large-format facility cameras, and since 2016 with the High-resolution Fast Imager (HiFI). These data are processed in standardized procedures with the aim of providing science-ready data for the solar physics community. For this purpose, we have developed a user-friendly data reduction pipeline called “sTools” based on the Interactive Data Language (IDL) and licensed under creative commons license. The pipeline delivers reduced and image-reconstructed data with a minimum of user interaction. Furthermore, quick-look data are generated as well as a webpage with an overview of the observations and their statistics. All the processed data are stored online at the GREGOR GFPI and HiFI data archive of the Leibniz Institute for Astrophysics Potsdam (AIP). The principles of the pipeline are presented together with selected high-resolution spectral scans and images processed with sTools.
Small magnetic structures near the polar regions of the Sun
Authors: Cabello I. , Rodríguez J. Blanco , Balmaceda L. , Domingo V. 
Published: September 2017

AbstractThe study of the small magnetic structures of the solar photosphere is of great relevance because of their association with concentrations of magnetic field and their possible contribution to the variations of the Total Solar Irradiance. These structures are known to appear close to active regions and ubiquitously in the quiet Sun areas. Numerous studies about their distribution across all over the solar surface have been done with high-resolution instrumentation. However, since the observations have always been carried out from the ecliptic plane, their distribution near the polar regions is not well known. Future missions, like Solar Orbiter, will certainly provide valuable information on these yet unexplored regions. In this work, and in preparation for that moment, we select favorable periods for the observation of the polar regions of the Sun, and study the fraction of covered surface by small magnetic structures and its variation with the solar activity.