bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanical Properties of ABS Embedded with Basalt Fiber Fillers
Authors: Abdelhaleem Ayman M. M. , Abdellah Mohammed Y. , Fathi Hesham I. , Dewidar Montasser 
Published: May 2016

AbstractAcrylonitrile-butadiene-styrene (ABS) has great verity applications in aerospace and automobiles industries. Mechanical strength of the ABS is superior to even that of impact resistant polystyrene. In addition metallic coatings can be applied to the surface of ABS moldings. The main aim of the present work is to investigate the mechanical properties of additives of basalt fibers (BF) to ABS with (5, 10, and 15) wt% embedded into the polymer matrix by using plastic injection molding technique. This new perceptions has been done on basalt fibers that have a potential low cost with its good mechanical performance. The ultimate tensile strength that obtained from the composite with 15 wt% is 56.67 MPa with 40.52 % increase value than neat ABS, Young’s modulus gradually increases with increasing the amount of additives. Impact un-notched strength decreases with a reported increment of 24.617 KJ.m–2. A Rockwell hardness test is also used and with the increases of additives the amount of hardness of the composite increases. A scan electron microscopy (SEM) on the fracture surface is captured to check the morphologies structure of the composite comparable with a neat ABS. and it is showed a very good distribution and bonding of the B.F. with the pure ABS. As well as the cost of the ABS and BF is reduced by a percentage of 15 %.
Zoledronate for Osteogenesis imperfecta: evaluation of safety profile in children
Authors: Kumar Chanchal , Panigrahi Inusha , Somasekhara Aradhya Abhishek , Meena Babu Lal , Khandelwal Niranjan 
Published: May 2016

Abstract

Background:
The advent of bisphosphonates (BPs) has revolutionised the outcome of Osteogenesis imperfecta (OI) in the last few years. There has always been a safety concern regarding zoledronate’s use due to a paucity of studies. The current study is a retrospective evaluation of children with OI on the short- and long-term side effects of zoledronate and the frequency of fractures per year after the drug was introduced.

Methods:
A total of 26 children diagnosed with OI, with a median age of 84 (45–121) months were enrolled in the study. They received cyclical zoledronate for a median duration of 36 (11–61) months at quarterly intervals between January 2008 and December 2014. Safety evaluation involved assessment of its short- and long-term effects in addition to the frequency of fractures after its usage.

Results:
One (3%) neonate had symptomatic hypocalcemia 15 days after the infusion. Three children (11%) had acute phase reactions. None had long-term side effects, including osteonecrosis of the jaw, in our 7-year experience. OI of types III and IV (total of 22) had significant reductions in the number of fractures (p<0.05).

Conclusions:
Further long-duration studies are necessary to evaluate the longterm safety of zoledronate.
Evaluation of left and right ventricular functions using conventional and tissue Doppler echocardiography in children with type 1 diabetes mellitus
Authors: Caglar Acar Onur , Epcacan Serdar , Uner Abdurrahman , Ece Ibrahim , Dogan Murat 
Published: May 2016

Abstract

Background:
The aim of the study was the evaluation of the effects of glycemic control in children and adolescents with type 1 diabetes on cardiac functions.

Methods:
Diabetic patients were divided into two groups as well-controlled and poorly controlled patients. All patients underwent M-mode, two-dimensions (2D), pulsed wave (PW) Doppler, and tissue Doppler (TDI) echocardiography to evaluate systolic and diastolic functions.

Results:
Early diastolic mitral flow velocity (Em) and the ratio of early to late diastolic mitral flow velocity (Em/Am) obtained with TDI were found to be significantly lower in the well-controlled then the control group and significantly lower in the poorly-controlled group than the well-controlled group. Am, isovolumetric relaxation time (IVRT) and myocardial performance index (MPI) were significantly higher in the poorly controlled group. The ratio of early mitral diastolic flow velocity obtained with PW Doppler (E) to Em (E/Em) was significantly higher in the diabetic group. According to the mitral valve PW Doppler results, 13.6% of the well-controlled group and 31% of the poorly-controlled group had type 1 diastolic dysfunction. According to the mitral TDI results, 18% of the well-controlled group and 40.4% of poorly-controlled group had type 1 diastolic dysfunction.

Conclusions:
Conventional and TDI echocardiography revealed impairment in left ventricular functions in some patients. Tissue Doppler echocardiography also revealed diastolic impairment in some patients who appeared normal with PW Doppler echocardiography. The present study found that impairment in left ventricular diastolic functions is directly related to glycemic control and the rate of diabetic cardiomyopathy was higher in children with poor metabolic control.
Central precocious puberty in a boy with 22q13 deletion syndrome and NOTCH-1 gene duplication
Authors: Giannakopoulos Aris , Fryssira Helen , Tzetis Maria , Xaidara Athina , Kanaka-Gantenbein Christina 
Published: May 2016

AbstractThe 22q13 deletion syndrome or Phelan-McDermid syndrome is a neurodevelopmental disorder associated with developmental delay, hypotonia, delayed or absent speech, autistic-like behavior, normal to accelerated growth and dysmorphic faces. We report the occurrence of central precocious puberty in a boy diagnosed with Phelan-McDermid syndrome. At the age of 1 year, our patient presented with increased testicular volume for his age, bone age advancement and growth acceleration. Stimulated gonadotropin levels demonstrated a premature activation of the hypothalamic-pituitary-gonadal (HPG) axis. Central precocious puberty was treated with gonadotropin-releasing hormone (GnRH) analog. Molecular diagnosis with array-comparative genomic hybridization (CGH) revealed a major deletion of 5.8 Mb at the 22q13 chromosomal region and a 25 kb duplication at the 9q34.3 region that included the
Elevated serum adiponectin is related to elevated serum ferritin and interleukin-6 in β-thalassaemia major children
Authors: El-Rasheidy Farida H. , Essa Enas S. , Mahmoud Asmaa A.S. , Nada Abd El-wahab A.A. 
Published: May 2016

Abstract

Background:
There is evidence that iron affects lipid metabolism and adipocyte biology. Given the effects of iron on adiponectin, the role of iron in lipid oxidation, and the potential additive effects of oxidative stress from excess iron and lipid metabolism. We aimed to investigate serum adiponectin in relation to clinical and laboratory parameters including the inflammation markers [C-reacitve protein (CRP) and interleukin-6 (IL-6)] in β-thalassaemia major children.

Methods:
We investigated 58 β-thalassaemia major children under scheduled blood transfusion and 30 controls. Routine clinical evaluation, laboratory investigations including serum ferritin as well as CRP measured by immunoturbidimetry, IL-6 and serum adiponectin measured by ELISA are performed.

Results:
CRP, IL-6 and serum adiponectin levels were higher in patients than controls (p<0.001, p=0.04 and p<0.001, respectively). Patients received desferoxamine showed significantly lower levels of adiponectin than those did not receive it (mean±SD=4.50±3.37 vs. 9.96±9.68, p=0.006). Serum adiponectin was significantly negatively correlated with hemoglobin (Hb) concentration (r=–0.36, p=0.005). It was significantly positively correlated with platelets count, serum ferritin, CRP and IL-6 (r=0.27, r=0.26, r=0.30, r=0.35, respectively and p=0.04, p=0.04, p=0.01, p=0.008, respectively). Serum ferritin and IL-6 were the significant predictors of serum adiponectin level (p<0.001 and p=0.003, respectively).

Conclusions:
Serum adiponectin was increased in β-thalassaemia major as were pro-inflammatory markers (CRP and IL-6). Its level is directly associated with ferritin and IL-6 levels.
Effect of DHA supplements during pregnancy on the concentration of PUFA in breast milk of Chinese lactating mothers
Authors: Deng Juan , Li Xiang , Ding Zhen , Wu Yixia , Chen Xueyan , Xie Lin 
Published: May 2016

Abstract

Objective:
To determine whether there is an effect of prenatal supplementation with docosahexaenoic acid (DHA) on the concentration of polyunsaturated fatty acids (PUFAs) in the breast milk of Chinese lactating women.

Methods:
A total of 409 participants were recruited at the postpartum care center during their 1-month postpartum care. They were assigned to the supplement group or the control group according to whether or not DHA supplements were taken during pregnancy. Dietary intake was assessed with a food frequency questionnaire (FFQ). Breast milk samples were collected on 1 day between the 22nd and 25th day postpartum and levels of eight kinds of fatty acids in the breast milk were measured by gas chromatography.

Results:
DHA intake was divided into three levels (<57 mg/day, 57–185 mg/day and >185 mg/day). The concentration of DHA postpartum in the breast milk of the group receiving a DHA supplement >185 mg/day was significantly higher (P=0.003) compared to the control group.

Conclusions:
DHA intake >185 mg/day resulted in increased DHA concentrations in breast milk. This finding suggests that mothers with inadequate dietary intake of DHA should change their dietary habits to consume a diet rich in DHA or take sufficient DHA supplements to meet the average nutritional needs of infants.
Risk factors of uterine rupture with a special interest to uterine fundal pressure
Authors: Sturzenegger Karin , Schäffer Leonhard , Zimmermann Roland , Haslinger Christian 
Published: May 2016

AbstractPurpose:Uterine rupture is a rare but serious event with a median incidence of 0.09%. Previous uterine surgery is the most common risk factor. The aim of our study was to analyze retrospectively women with uterine rupture during labor and to evaluate postulated risk factors such as uterine fundal pressure (UFP).Methods:Twenty thousand one hundred and fifty-two deliveries were analyzed retrospectively. Inclusion criteria were 22 weeks and 0 days–42 weeks and 0 days of gestation, singleton pregnancy and cephalic presentation. Women with primary cesarean section were excluded. A logistic regression analysis adjusting for possible risk factors was conducted and a subgroup analysis of women with unscarred uterus was performed.Results:Twenty-eight cases of uterine rupture were identified (incidence: 0.14%). Uterine rupture was noticed in multipara patients only. In the multivariate analysis among all study patients, only previous cesarean section remained a statistically significant risk factor [adjusted odds ration (adj. OR) 12.52 confidence interval (CI) 95% 5.21–30.09]. In the subgroup analysis among women with unscarred uterus (n=19,415) three risk factors were associated with uterine rupture: UFP (adj. OR 5.22 CI 95% 1.07–25.55), abnormal placentation (adj. OR 20.82 CI 95% 2.48–175.16) and age at delivery >40 years (adj. OR 4.77 CI 95% 1.44–15.85).Conclusions:The main risk factor for uterine rupture in the whole study population is previous uterine surgery. Risk factors in women with unscarred uterus were UFP, abnormal placentation, and age at delivery >40 years. The only factor which can be modified is UFP. We suggest that UFP should be used with caution at least in presence of other supposed risk factors.
Can laser therapy be the answer for radiodermatitis in anal cancer patients? Two case reports
Authors: Gobbo Margherita , Ottaviani Giulia , Rupel Katia , Biasotto Matteo , Guglielmi Alessandra 
Published: May 2016

Abstract

Background:
Patients suffering from anal cancer have to undergo different anticancer therapies, including radiotherapy. Radiodermatitis represents a debilitating side effect of radiotherapy, often leading to painful lesions and a suspension of the radiotherapy treatment. No widely recognized treatment of radiodermatitis is currently available.

Objective:
The present report introduces an innovative technique based on the use of laser light to manage radiodermatitis of the anal region in a decisive fashion.

Study design:
Two cases of radiodermatitis are presented, the occurrence of which followed combined chemoradiotherapy for anal squamous cell carcinoma. Both patients complained about strong pain, severe itch and spontaneous bleeding from the lesions. In addition, they reported limitations in their daily life activities as well as a negative impact on their quality of life. Both patients received laser irradiation therapy by applying two wavelengths simultaneously (970±15 nm and 660±15 nm) for a total of six laser sessions. The chosen treatment parameters were as follows: peak power, 6 W, 50% duty cycle for 360 s; peak power, 6 W in continuous mode for another 120 s resulting in spatially averaged energy fluences of 67.5 J/cm2 and 45 J/cm2, respectively.

Results:
Complete healing of the lesions and symptoms was achieved within 2 weeks. Remission of the symptoms continued after 2 months with no documented side effects. Both patients managed to complete the radiotherapy sessions and reported maximum satisfaction with the treatment.

Conclusions:
These cases can prepare the ground to consider class-IV laser therapy, an innovative option to manage radiodermatitis with predictable effectiveness and a consequent improvement in the quality of life of the patients. Patients experiencing radiodermatitis suffer from pain accompanied by limited independence in daily activities, decreased life quality, and reduced self-esteem which often leads to depression. Resolution of radiodermatitis can result in fewer cases of radiotherapy suspension and a better outcome in the oncological treatment as well as an improved quality of life, usually very quickly.
La conversaciónguasap
Authors: Gascueña Rosa Martín 
Published: May 2016

ResumenEsta investigación sobre la aplicación para teléfonos móviles inteligentesWhatsAppse enfoca desde los presupuestos del análisis de la conversación coloquial (Briz y Grupo Val.Es.Co, 2000). Se propone una configuración estructural de estas conversaciones basada en secuencias de apertura, continuidad y cierre. Nuestro objetivo es describir las estrategias comunicativas y discursivas empleadas en este canal de comunicación tan cotidiano, y comprobar, por un lado, cómo los elementos no exclusivamente lingüísticos funcionan como anclajes semánticos que sirven para cohesionar y referenciar la información inferida de cada acto de habla y, por otro, cómo se utilizan estos elementos en la negociación de las relaciones sociales y guían la interacción. Así pues, la funcionalidad de los emoticonos es múltiple; a veces pueden sustituir a unidades léxicas y, en ocasiones, vehiculan la interpretación de la emoción del enunciador. Además, otras veces recapitulan la intención del enunciador y también pueden ser elementos de (des)cortesía (según al grado de confianza que mantengan los interlocutores). Por otra parte, su uso está relacionado con variables diatópicas, diastráticas y diafásicas. Para esta investigación hemos analizado cien conversaciones de once grupos integrados por un número variable de tres a doce individuos por grupo, con edades comprendidas entre los doce y los sesenta años.
Discurso institucional e imagen en los mensajes de Navidad del rey de España (1975–2013)
Authors: López Javier Medina 
Published: May 2016

ResumenLos mensajes de Navidad del rey Juan Carlos I constituyen una de las pocas ocasiones en las que el jefe del Estado español se dirige a los españoles a través de la televisión. El objetivo principal de este artículo es analizar estos textos emitidos por el monarca en el período de su reinado (1975–2013). Estamos ante unos mensajes que los pronuncia el representante de la institución de la Corona, pero que no tienen el correspondiente refrendo legal. Son costumbres y tradiciones aceptadas por todos. El estudio se lleva a cabo desde la perspectiva del análisis del discurso y desde la semiótica de la comunicación, para poner de relieve cómo el texto es utilizado con fines ideológicos para consolidar la imagen de la Monarquía, a la vez que la estructura del Estado. Las figuras delethosy de laauctoritasreales se ponen de relieve cuando se quiere afianzar la imagen del monarca y de la institución que encarna. Los mensajes siguen el modelo de la oratoria clásica y se utilizan como medio para comentar, persuadir y arbitrar un marco de convivencia en España en la que el rey juega un papel de moderador entre el Estado y la ciudadanía.
“Mais vous avez tout à fait raison M. le Premier ministre”Termes d’adresse et débats politiques télévisés de l’entre-deux-tours (1974–2012)
Authors: Sullet-Nylander Françoise , Roitman Malin 
Published: May 2016

Résumé
Depuis 1974, le débat de l’entre-deux-tours affrontant les “finalistes” avant le second tour des élections présidentielles est devenu une “institution” en France (1974: Giscard d’Estaing / Mitterrand; 1981: Mitterrand / Giscard d’Estaing; 1988: Mitterrand / Chirac; 1995: Chirac / Jospin; 2007: Sarkozy / Royal et 2012: Hollande / Sarkozy). Après avoir mené plusieurs études linguistico-discursives sur ce même corpus − en particulier sur les modes de questionnement, la réfutation et les formes de discours rapporté −, les auteures s’intéressent ici aux termes d’adresses utilisés par les deux candidats en face-à-face dans les six débats susnommés. Les études de l’ouvrage dirigé par Catherine Kerbrat-Orecchioni (2010), S’adresser à autrui. Les formes nominales d’adresse en français, ont bien a montré que les usages appellatifs varient considérablement d’un genre interactionnel à l’autre. Il semble ainsi justifier de mener une étude approfondie, à la fois quantitative et qualitative, de l’évolution de ces usages appellatifs au sein du genre discursif des débats politiques télévisés de l’entre-deux-tours, ceux-ci couvrant une période d’une quarantaine d’années. Les auteures s’interrogent sur les formes (Monsieur +  patronyme, Madame +  patronyme, Monsieur le Premier ministre, etc.) des termes d’adresse et sur la fréquence avec laquelle ils sont utilisés au fil des décennies. L’analyse porte également sur l’emploi de ces formes en allocution et / ou en délocution et sur les fonctions pragmatiques que jouent ces unités dans les débats de l’entre-deux-tours.
A highly efficient CuI nanoparticles-catalyzed synthesis of tetrahydrochromenediones and dihydropyrano[c]chromenediones under grinding
Authors: Abdolmohammadi Shahrzad , Ghiasi Reza , Ahmadzadeh-Vatani Sam 
Published: May 2016

Abstract
A concise and CuI nanoparticle-catalyzed synthesis of tetrahydrochromenediones and dihydropyrano[c]chromenediones under solvent-free grinding conditions via the three-component condensation reaction of Meldrum’s acid, an aromatic aldehyde, and an active methylene compound, including dimedone or 4-hydroxycoumarin, was developed. This new method gives desirable advantages such as simple reaction setup, very mild reaction conditions, production of the desired products in high yields without by-products, recyclability of the catalyst, and environmentally benign procedure.
Resistance Training Alters the Proportion of Skeletal Muscle Fibers but Not Brain Neurotrophic Factors in Young Adult Rats
Authors: Antonio-Santos José , Ferreira Diórginis José S. , Gomes Costa Gizelle L. , Matos Rhowena Jane B. , Toscano Ana E. , Manhães-de-Castro Raul , Leandro Carol G. 
Published: May 2016

Abstract
Antonio-Santos, J, Ferreira, DJS, Gomes Costa, GL, Matos, RJB, Toscano, AE, Manhães-de-Castro, R, and Leandro, CG. Resistance training alters the proportion of skeletal muscle fibers but not brain neurotrophic factors in young adult rats. J Strength Cond Res 30(12): 3531–3538, 2016—Resistance training (RT) is related to improved muscular strength and power output. Different programs of RT for rats have been developed, but peripheral and central response has not been evaluated directly in the same animal. To test the hypothesis that RT induces central and peripheral adaptations, this study evaluated the effects of a RT on the performance of a weekly maximum overload test, fiber-type typology, and brain neurotrophic factors in young adult rats. Thirty-one male Wistar rats (65 ± 5 days) were divided in 2 groups: nontrained (NT, n = 13) and trained (T, n = 18). Trained group was submitted to a program of RT ladder climbing, gradually added mass, 5 days per week during 8 weeks at 80% of individual maximum overload. This test was weekly performed to adjust the individual load throughout the weeks for both groups. After 48 hours from the last session of exercise, soleus and extensor digital longus (EDL) muscles were removed for myofibrillar ATPase staining analysis. Spinal cord, motor cortex, and cerebellum were removed for RT-PCR analysis of BDNF and insulin-like growth factor-1 (IGF-1) gene expression. In EDL muscle, T animals showed an increase in the proportion of type IIb fibers and a reduction of type IIa fibers. Insulin-like growth factor-1 gene expression was reduced in the cerebellum of T animals (NT: 1.025 ± 0.12; T: 0.57 ± 0.11). Our data showed that 8 weeks of RT were enough to increase maximum overload capacity and the proportion of glycolytic muscle fibers, but there were no associations with the expression of growth neurotrophic factors.
Longitudinal Body Composition Changes in NCAA Division I College Football Players
Authors: Trexler Eric T. , Smith-Ryan Abbie E. , Mann J. Bryan , Ivey Pat A. , Hirsch Katie R. , Mock Meredith G. 
Published: May 2016

Abstract
Trexler, ET, Smith-Ryan, AE, Mann, JB, Ivey, PA, Hirsch, KR, and Mock, MG. Longitudinal body composition changes in NCAA Division I college football players. J Strength Cond Res 31(1): 1–8, 2017—Many athletes seek to optimize body composition to fit the physical demands of their sport. American football requires a unique combination of size, speed, and power. The purpose of the current study was to evaluate longitudinal changes in body composition in Division I collegiate football players. For 57 players (mean ± SD, age = 19.5 ± 0.9 years, height = 186.9 ± 5.7 cm, weight = 107.7 ± 19.1 kg), body composition was assessed via dual-energy x-ray absorptiometry in the off-season (March-Pre), end of off-season (May), mid-July (Pre-Season), and the following March (March-Post). Outcome variables included weight, body fat percentage (BF%), fat mass, lean mass (LM), android and gynoid (GYN) fat, bone mineral content (BMC), and bone mineral density (BMD). For a subset of athletes (n = 13 out of 57), changes over a 4-year playing career were evaluated with measurements taken every March. Throughout a single year, favorable changes were observed for BF% (Δ = −1.3 ± 2.5%), LM (Δ = 2.8 ± 2.8 kg), GYN (Δ = −1.5 ± 3.0%), BMC (Δ = 0.06 ± 0.14 kg), and BMD (Δ = 0.015 ± 0.027 g·cm−2, all p ≤ 0.05). Across 4 years, weight increased significantly (Δ = 6.6 ± 4.1 kg) and favorable changes were observed for LM (Δ = 4.3 ± 3.0 kg), BMC (Δ = 0.18 ± 0.17 kg), and BMD (Δ = 0.033 ± 0.039 g·cm−2, all p ≤ 0.05). Similar patterns in body composition changes were observed for linemen and non-linemen. Results indicate that well-trained collegiate football players at high levels of competition can achieve favorable changes in body composition, even late in the career, which may confer benefits for performance and injury prevention.