bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genomic epidemiology describes introduction and outbreaks of antifungal drug-resistant Candida auris
Authors: Kappel Dana , Gifford Hugh , Brackin Amelie , Abdolrasouli Alireza , Eyre David W. , Jeffery Katie , Schlenz Silke , Aanensen David M. , Brown Colin S. , Borman Andrew , Johnson Elizabeth , Holmes Alison , Armstrong-James Darius , Fisher Matthew C. , Rhodes Johanna 
Published: September 2024

AbstractCandida auris is a globally emerged fungal pathogen causing nosocomial invasive infections. Here, we use cutting-edge genomic approaches to elucidate the temporal and geographic epidemiology of drug-resistant C. auris within the UK. We analysed a representative sample of over 200 isolates from multiple UK hospitals to assess the number and timings of C. auris introductions and infer subsequent patterns of inter- and intra-hospital transmission of azole drug-resistant isolates. We identify at least one introduction from Clade I and two from Clade III into the UK, and observe temporal and geographical evidence for multiple transmission events of antifungal drug resistant isolates between hospitals and identified local within-hospital patient-to-patient transmission events. Our study confirms outbreaks of drug-resistant C. auris are linked and that transmission amongst patients occurs, explaining local hospital outbreaks, and demonstrating a need for improved epidemiological surveillance of C. auris to protect patients and healthcare services.
Exploring Culturally Responsive Voice Care: Introduction
Authors: Sund Lauren Timmons , Morton-Jones Mariah E. , Castro M. Eugenia 
Published: September 2024

Purpose:
The purpose of this introduction is to broadly discuss cultural responsiveness and serve as a prelude to the forum articles, which discuss specific aspects of cultural responsiveness within voice care.

Conclusion:
Cultural responsiveness encompasses practices that consider the patient's cultural beliefs, values, and perspectives in all aspects of the therapeutic process. Voice is a cultural construct, and as such, the presence or impact of a voice disorder is impacted by a patient's culture. Each article in this forum is briefly introduced.
Correction‐enabled reversible data hiding with pixel repetition for high embedding rate and quality preservation
Authors: Kawser Mohammad Ali , Nyeem Hussain , Wahed Md Abdul 
Published: September 2024

AbstractA novel correction‐enabled Pixel Repetition (PR)‐based Reversible Data Hiding (RDH) framework, featuring a new embedding scheme is presented. The proposed RDH scheme uses contextually redundant block pixels, generated via PR, in a two‐phase adaptive embedding process, enhancing both image quality and data embedding rates. Specifically, each block encodes 4 bits of data using new mapping conditions that facilitate seed pixel reconstruction from remaining block pixels and provide additional embedding opportunities. Additionally, an innovative post‐embedding error correction technique, based on ‐bit error‐correction, minimises post‐embedding distortion, further improving image quality. This error correction approach augments data embedding robustness, vital for applications like medical imaging, telemedicine, and digital watermarking that requires high embedding capacity with minimum possible distortion. The proposed scheme surpasses existing state‐of‐the‐art methods in embedding rate‐distortion performance, validated through subjective and objective analyses. Furthermore, statistical analysis, including histogram and fragility testing, confirms the scheme's potential for image authentication across diverse multimedia applications. The correction‐enabled RDH with PR offers enhanced embedding capacity and image quality preservation, making it particularly advantageous for applications requiring robust data hiding while maintaining visual fidelity.
Parameter identification of PV solar cells and modules using bio dynamics grasshopper optimization algorithm
Authors: Jabari Mostafa , Rad Amin , Nasab Morteza Azimi , Zand Mohammad , Padmanaban Sanjeevikumar , Muyeen S. M. , Guerrero Josep M. 
Published: September 2024

AbstractThe escalating global population and energy demands underscore the critical role of renewable energy sources, particularly solar power, in mitigating environmental degradation caused by traditional fossil fuels. This paper emphasizes the advantages of solar energy, especially photovoltaic (PV) systems, which have become pivotal in hybrid energy systems. However, accurate modelling and identification of PV cell parameters pose challenges, prompting the adoption of meta‐heuristic optimization algorithms. This work explores the limitations of existing algorithms and introduces a novel approach, the bio‐dynamics grasshopper optimization algorithm (BDGOA). The BDGOA addresses deficiencies in both exploration and exploitation phases, exhibiting exceptional convergence speed and efficiency. The algorithm's simplicity, achieved through the implementation of an elimination phase and controlled search space, enhances its performance without intricate calculations. The study evaluates the BDGOA by applying it to identify unknown parameters of five solar modules. The algorithm's effectiveness is demonstrated through the extraction of parameters for RTC France, PWP201, SM55, KC200GT, and SW255 models, validated against experimental data under diverse conditions. The paper concludes with insights into the impact of radiation and temperature on module parameters. The subsequent sections of the paper delve into the intricacies of the PV cell and module model, articulate the formulation of the proposed algorithm, present simulations, and analyse the obtained results. The BDGOA emerges as a promising solution, overcoming the limitations of existing algorithms and contributing significantly to the advancement of accurate and efficient PV cell parameter identification, thereby propelling progress towards a sustainable energy future.
High‐speed, two‐stage operational transconductance amplifier without Miller capacitor, suitable for large capacitive load
Authors: Rashtian Mohammad , Shahpasandi Mahdi , Parastari Javad 
Published: September 2024

AbstractA two‐stage Class A‐AB operational transconductance amplifier with low power consumption, high slew rate, and high bandwidth is introduced for handling large capacitive loads. Unlike the conventional two‐stage operational transconductance amplifiers that use a Miller capacitor, compensation is provided by the load capacitor (CL) at the output node. The proposed two‐stage amplifier maintains a 45° phase margin (PM) over any load capacitance. This is achieved through a MOSFET‐based RC network at the output node. Dual nMOS/pMOS differential stages drive output directly, improving both SR+ and SR−. Post‐layout simulation results with a capacitive load of 100 pF (CL) demonstrate that the proposed operational transconductance amplifier has a DC gain of 60.1 dB, an excellent average slew rate of 20.3 V/µs, a gain‐bandwidth product of 10.6 MHz, an average 1% settling time of 122.2 ns and a PM of 76.6°, while consuming only 103.5 µW. Reducing the CL to 10 pF reduces the PM to 47.6°, while increasing the gain‐bandwidth and average slew rate to 82.9 MHz and 142.6 V/µs respectively.
Mass scaling relations for dark halos from an analytic universal outer density profile
Authors: Korkidis Giorgos , Pavlidou Vasiliki 
Published: September 2024

Context. The average matter density within the turnaround scale, which demarcates where galaxies shift from clustering around a structure to joining the expansion of the Universe, is an important cosmological probe. However, a measurement of the mass enclosed by the turnaround radius is difficult. Analyses of the turnaround scale in simulated galaxy clusters place the turnaround radius at about three times the virial radius in a ΛCDM universe and at a (present-day) density contrast with the background matter density of the Universe of δ ~ 11. Assessing the mass at such extended distances from a cluster’s center is a challenge for current mass measurement techniques. Consequently, there is a need to develop and validate new mass-scaling relations, to connect observable masses at cluster interiors with masses at greater distances.
Aims. Our research aims to establish an analytical framework for the most probable mass profile of galaxy clusters, leading to novel mass scaling relations, allowing us to estimate masses at larger scales. We derive such analytical mass profiles and compare them with those from cosmological simulations.
Methods. We used excursion set theory, which provides a statistical framework for the density and local environment of dark matter halos, and complement it with the spherical collapse model to follow the non-linear growth of these halos.
Results. The profile we developed analytically showed good agreement (better than 30%, and dependent on halo mass) with the mass profiles of simulated galaxy clusters. Mass scaling relations were obtained from the analytical profile with offset better than 15% from the simulated ones. This level of precision highlights the potential of our model for probing structure formation dynamics at the outskirts of galaxy clusters.
Endoscopic ultrasound-guided tissue acquisition for focal liver lesions can be safely performed in patients with ascites
Authors: Takano Yuichi , Tamai Naoki , Yamawaki Masataka , Noda Jun , Azami Tetsushi , Niiya Fumitaka , Nishimoto Fumiya , Maruoka Naotaka , Yamagami Tatsuya , Nagahama Masatsugu 
Published: September 2024

Abstract
Background and study aims In patients with ascites, percutaneous liver biopsy is generally contraindicated. Because endoscopic ultrasound-guided tissue acquisition (EUS-TA) allows tissue sample obtention from the digestive tract lumen, a biopsy without the intervention of ascites may prevent adverse events (AEs). This study aimed to evaluate the safety of EUS-TA for focal liver lesions in the presence of ascites.
Patients and methods A retrospective study was conducted using medical records of cases in which EUS-TA was performed on focal liver lesions between 2016 and 2022. Study participants were classified into two groups: those with ascites and those without it, and the outcomes were compared. The primary outcome was AEs.
Results We included 109 cases of EUS-TA for focal liver lesions. Ascites was present in 20.1% of cases (22/109) and absent in 79.8% of cases (87/109). There were no significant differences between the two groups in clinical backgrounds and EUS-TA procedure, although fine-needle biopsy needles were significantly more frequently used in patients without ascites. In the ascites group, puncture without intervening ascites was successful in 90.9% of cases (20/22). The incidence of AEs was 4.5% (1/22) in the ascites group and 1.1% (1/87) in the non-ascites group, showing no significant difference. The two AEs were mild self-limiting abdominal pain.
Conclusions In focal liver lesions with ascites, EUS-TA allows biopsy without the intervention of ascites in most cases. The incidence of AEs did not differ significantly between patients with and without ascites.
Mechanisms and Research Progress of Traditional Chinese Medicine Regulating NF-κB in the Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome
Authors: Zuo Wanzhao , Tian Fanian , Ke Jia , Jiang Cheng , Yang Yi , He Cong 
Published: September 2024

AbstractAcute lung injury (ALI) has multiple causes and can easily progress to acute respiratory distress syndrome (ARDS) if not properly treated. Nuclear factor κB (NF-κB) is a key pathway in the treatment of ALI/ARDS. By exploring the relevance of NF-κB and the pathogenesis of this disease, it was found that this disease was mainly associated with inflammation, dysfunction of the endothelial barrier, oxidative stress, impaired clearance of alveolar fluid, and coagulation disorders. Traditional Chinese medicine (TCM) has the characteristics of multitargeting, multipathway effects, and high safety, which can directly or indirectly affect the treatment of ALI/ARDS. This article summarizes the mechanism and treatment strategies of TCM in recent years through intervention in the NF-κB-related signaling pathways for treating ALI/ARDS. It provides an overview from the perspectives of Chinese herbal monomers, TCM couplet medicines, TCM injections, Chinese herbal compounds, and Chinese herbal preparations, offering insights into the prevention and treatment of ALI/ARDS with TCM.
The Chinese Herbal Formula Weichang'an Reduces the Proliferation of Human Gastric Cancer Cells via Mitochondrial Apoptosis
Authors: Chen Weixia , Niu Yaofei , Chen Bin , Zhao Aiguang 
Published: September 2024

Abstract
Objective The aim of the study was to investigate the effects of Chinese herbal formula Weichang'an (WCA) on the proliferation and mitochondria-mediated apoptosis of human gastric cancer cells.
Methods Cell Counting Kit-8 (CCK8) was used to evaluate the antiproliferative activity of WCA on MKN45 cells; Giemsa staining was used to investigate cell colony formation; flow cytometry was used to analyze cell cycle, apoptosis rate, and caspases activation; and Hoechst staining was used to analyze the morphology of cell nuclei. The mitochondrial membrane potential was analyzed by both flow cytometric measurements and fluorescence microscopy. Western blot was used to analyze the protein levels of pro-caspase-3, Bcl-2, Bax, and Bcl-X. MKN45 cells were subcutaneously injected into the right forelimb of 16 nude mice to establish the tumor xenograft model, and a total of 12 nude mouse tumor xenograft models were successfully created. The nude mice were divided into the control group and the WCA-treated group. The two groups received normal saline and WCA treatment at 35.49 g/kg by a single daily oral gavage for 21 days. The body weight and tumor size of the nude mice were measured twice a week. The ultrastructural changes of subcutaneous tumors were observed by a transmission electron microscope.
Results WCA can suppress cell proliferation and colony formation. It can also induce changes in the mitochondrial membrane potential and increase the activities of caspases-3, caspases-8, and caspases-9 in MKN45 cells. WCA induced S-phase arrest and apoptosis in MKN45 cells, and decreased the expression levels of antiapoptotic proteins Bcl-2 and Bcl-X in MKN45 cells, while increasing the expression levels of the proapoptotic proteins Bax and pro-caspase-3 compared with the control group. WCA inhibited the growth of a xenografted MKN45 tumor in nude mice, and the protein levels of Bax and pro-caspase-3 were significantly increased, while Bcl-X and Bcl-2 were reduced compared with the control group. The differences are statistically significant (p < 0.05).
Conclusion WCA could suppress the proliferation of gastric cancer cells via mitochondrial apoptosis.
Holistic Integrative Medicine Declaration- Secondary publication
Authors: Fan Daiming 
Published: September 2024

AbstractHolistic integrative medicine, abbreviated as HIM, has been officially proposed since 2012. Its theoretical system has been continuously improved, and its practical methods have become increasingly diverse, becoming an inevitable choice and path for the medical development in the new era. This article demonstrates ten major propositions for HIM, elaborating on the connotation and extension of HIM from the perspectives of epistemology and methodology, in order to achieve the transformation and adaptive evolution of modern medicine.
Roadmap to Success: Illustrating Insights from a KAP Study on Cervical Cancer Prevention and HPV Vaccination
Authors: Ganeshkumar Priya , Tank Jaydeep , Choudhury Saswati Sanyal , Acharya Veena , Gaur Yashodhara , Srivastava Reena , Janakiraman Revathy , Ganeshkumar Akshay 
Published: September 2024

Introduction Cervical cancer is a public health challenge in low- and middle-income countries, with India ranking among the highest in cervical cancer burden. The World Health Organization (has set ambitious targets for cervical cancer elimination by 2030, emphasizing the importance of human papillomavirus (HPV) vaccination and screening. In response, the National Technical Advisory Group of Immunization recommends the introduction of HPV vaccination for all eligible girls aged 9 to 14 years in India under the Universal Immunization Program. However, successful implementation requires both vaccine availability and changes in health care providers' knowledge, attitudes, and practices (KAP) regarding cervical cancer prevention and HPV vaccination.
Methodology This study aims to assess KAP among clinicians regarding cervical cancer and HPV vaccination. A cross-sectional survey collected responses from 451 practicing gynecologists and medical practitioners across 15 states of India. The questionnaire sought insights into patient inquiries, information sources, awareness levels, methods of patient education, and common myths and misconceptions.
Results Results indicate a high prevalence of patient inquiries about cervical cancer and the HPV vaccine, emphasizing the need for accurate and accessible information. While doctors were generally knowledgeable, misconceptions persisted among patients, including beliefs about low risk, inevitability of cervical cancer, and concerns about vaccine safety. Doctors primarily relied on verbal communication for patient education, suggesting potential for utilizing digital platforms and visual aids to enhance outreach.
Insights Insights from doctors underscored the importance of addressing misinformation and leveraging various communication channels, including social media, posters, and celebrity endorsements, to improve awareness and acceptance of vaccination. Disparities in vaccine availability and administration rates highlighted the need for targeted interventions to ensure equitable access.
Limitations Limitations of the study included its cross-sectional design and reliance on self-reported data, which may introduce bias. However, findings suggest a need for ongoing medical education and collaboration with stakeholders to drive awareness and acceptance of HPV vaccination.
Conclusion In conclusion, while gynecologists and medical practitioners demonstrate adequate KAP regarding cervical cancer prevention, there is room for improvement in patient education and communication strategies. Refining educational materials and strengthening communication channels would enhance awareness and reduce cervical cancer burden.
Three dimensional branching pipe flows for optimal scalar transport between walls
Authors: Kumar Anuj 
Published: September 2024

Abstract
We are interested in the design of forcing in the Navier–Stokes equation such that the resultant flow maximises the transport of a passive temperature between two differentially heated walls for a given power supply budget. This problem in the community is also known as ‘wall-to-wall optimal transport’ and can be reduced to optimizing the choice of the divergence-free velocity field in the advection-diffusion equation subject to an enstrophy constraint (which can be understood as a constraint on the power required to generate the flow). Previous work established that the transport cannot scale faster than 1/3-power of the power supply. Recently, Tobasco and Doering (2017 Phys. Rev. Lett.
118 264502) and Doering and Tobasco (2019 Commun. Pure Appl. Math.
72 2385–448) constructed self-similar two-dimensional steady branching flows saturating this bound up to a logarithmic correction. This correction appears to arise due to a topological obstruction inherent to two-dimensional steady flows. In this paper, we present a novel design of three-dimensional ‘branching pipe flows’ that bypasses this obstruction and, consequently, eliminates this logarithmic correction and therefore identifies the optimal scaling as a clean 1/3-power law. Our flows resemble the ones obtained in previous numerical studies of the three-dimensional wall-to-wall problem by Motoki, Kawahara and Shimizu (2018 J. Fluid Mech.
851 R4). We also discuss the implications of this result to the heat transfer problem in Rayleigh–Bénard convection and the problem of anomalous dissipation in a passive scalar.
A passive-tuned damper based on magnetorheological porous fabric composite
Authors: Wu Lifan , Dong Xiaomin , Xu Di 
Published: September 2024

Abstract
This paper proposes a novel passive-tuned magnetorheological (PTMR) damper based on developed magnetorheological (MR) porous fabric composite, in which the damping force is tuned by a permanent magnet (PM). Firstly, the influences of the porous fiber structure of composite on the suspended phase are considered, and a continuous constitutive model based on the dipole model is proposed for the first time, which can accurately predict its rheological properties. Subsequently, a stable passive damper for special conditions is designed, and the unique design concept is to achieve completely different damping characteristics for different application scenarios by adjusting the position of the PM relative to the magnetic circuit. The experimental results show that the damping force is relatively stable under specific condition, and can be adjusted within the range of 16.8–77.4 N, with a dynamic range of about 4.6. Moreover, the PTMR damper can exhibit unidirectional negative stiffness characteristic by adjusting the PM to a specific position. The PTMR damper has stable vibration reduction performance, wide dynamic range, and compact structure, which can be comparable to some conventional MR dampers.
Generating grating in cavity magnomechanics
Authors: Liu Wenzhang , Abbas Muqaddar , Hossein Asadpour Seyyed , Hamedi Hamid R , Zhang Pei , Sanders Barry C 
Published: September 2024

Abstract
We investigate the phenomenon of magnomechanically induced grating (MMIG) within a cavity magnomechanical system, comprising magnons (spins in a ferromagnet, such as yttrium iron garnet), cavity microwave photons, and phonons (Li et al 2018 Phys. Rev. Lett.
121 203601). By applying an external standing wave control, we observe modifications in the transmission profile of a probe light beam, signifying the presence of MMIG. Through numerical analysis, we explore the diffraction intensities of the probe field, examining the impact of interactions between cavity magnons, magnon-phonon interactions, standing wave field strength, and interaction length. MMIG systems leverage the unique properties of magnons, and collective spin excitations with attributes like long coherence times and spin-wave propagation. These distinctive features can be harnessed in MMIG systems for innovative applications in information storage, retrieval, and quantum memories, offering various orders of diffraction grating.
Pseudo-proper two-dimensional electron gas formation
Authors: Bennett Daniel , Aguado-Puente Pablo , Artacho Emilio , Bristowe Nicholas C 
Published: September 2024

Abstract
In spite of the interest in the two-dimensional electron gases (2DEGs) experimentally found at surfaces and interfaces, important uncertainties remain about the observed insulator–metal transitions (IMTs). Here we show how an explicit pseudo-proper coupling of carrier sources with a relevant soft mode significantly affects the transition. The analysis presented here for 2DEGs at polar interfaces is based on group theory, Landau–Ginzburg theory, and illustrated with first-principles calculations for the prototypical case of the

LaAlO
3

/

SrTiO
3

interface, for which such a structural transition has recently been observed. This direct coupling implies that the appearance of the soft mode is always accompanied by carriers. For sufficiently strong coupling an avalanche-like first-order IMT is predicted.