bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENINGKATAN EFEKTIVITAS PEMBELAJARAN MELALUI KREATIVITAS DAN INOVASI GURU DALAM MENCIPTAKAN KELAS YANG DINAMIS
Authors: Mea Firmina 
Published: October 2024

Pendidikan saat ini menghadapi tantangan signifikan, dengan kesulitan pemahaman materi oleh peserta didik yang disebabkan oleh pendekatan pengajaran tradisional dan rendahnya minat serta motivasi belajar, menekankan perlunya kreativitas dan inovasi guru untuk menciptakan kelas yang dinamis guna meningkatkan efektivitas pembelajaran. Tujuan penelitian ini adalah merinci praktik-praktik kreatif dan inovatif yang dapat diterapkan oleh guru, mengukur dampaknya terhadap partisipasi dan pemahaman peserta didik. Penelitian ini menerapkan metode kualitatif deskriptif dengan pendekatan studi kepustakaan, melalui pendekatan ini, diharapkan penelitian ini dapat memberikan kontribusi nyata pada pemahaman guru tentang bagaimana menciptakan kelas yang efektif dan memotivasi Berdasarkan hasil penelitian dapat disimpulkan bahwa pendidikan mengandalkan peran guru sebagai pembimbing utama yang memerlukan perencanaan yang sistematis. Kreativitas dan inovasi guru penting dalam proses pembelajaran, melibatkan penggunaan pendekatan kreatif dan respons terhadap dinamika kelas. Dalam manajemen kelas, tantangan kompleks dari dinamika sosial dan perkembangan teknologi membutuhkan inovasi terus-menerus untuk meningkatkan motivasi dan hasil belajar peserta didik mengalami peningkatan. Education today faces significant challenges, with learners struggling to understand material due to traditional teaching approaches and low interest and motivation to learn, emphasizing the need for teacher creativity and innovation to create dynamic classrooms to improve learning effectiveness. The aim of this research is to detail creative and innovative practices that teachers can implement and measure their impact on learner participation and understanding. This research applies a descriptive qualitative method with a literature study approach. Based on the results of the study, it can be concluded that education relies on the role of the teacher as the main guide, requiring systematic planning. Teacher creativity and innovation are important in the learning process, involving the use of creative approaches and responses to classroom dynamics. In classroom management, the complex challenges of social and technological dynamics require constant innovation to improve learner motivation and learning outcomes.
ĐÁNH GIÁ KHẢ NĂNG KHÁNG CÁC NHÓM VI KHUẨN GÂY ĐỘC THỰC PHẨM CỦA CHỦNG LỢI KHUẨN E. FAECIUM F26BA VÀ E. FAECIUM F54BA
Authors: Bùi Thị Lan Anh  , Nguyễn Thị Ngọc Sương  , Lê Thị Lan Anh  , Đào Nguyên Mạnh  , Hoàng Đức Hậu  , Võ Viết Cường  , Nguyễn Đắc Hiệu  , Đỗ Danh Thắng  
Published: October 2024

Mục tiêu: Đánh giá khả năng kháng vi khuẩn gây ngộ độc thực phẩm của hai chủng lợi khuẩn E. faecium F26BA và E. faecium F54BA (thành phần trong chế phẩm probiotic EntVN 500 mg).
Đối tượng và phương pháp: Nghiên cứu sử dụng hai chủng lợi khuẩn E. faecium F26BA và E. faecium F54BA là thành phần của chế phẩm probiotic EntVN 500 mg và các nhóm vi khuẩn gây độc thực phẩm phân lập tại Việt Nam (gồm 10 chủng E. coli sinh độc tố Shiga; 20 chủng Salmonella spp.; 10 chủng Shigella spp.; 2 chủng Staphylococcus aureus có độc tố). Phương pháp khuếch tán giếng thạch theo Ridwan được áp dụng để đánh giá hoạt tính kháng khuẩn của hai chủng lợi khuẩn.
Kết quả: Hai chủng lợi khuẩn F26BA và F54BA đều có tính kháng khuẩn mạnh với các nhóm vi khuẩn gây độc thực phẩm. Đường kính vùng ức chế của F26BA và F54BA với 10 chủng E. coli sinh độc tố Shiga; 20 chủng Salmollela spp.; 10 chủng Shigella spp.; 2 chủng Staphylococcus aureus có độc tố trong cả 3 lần thực nghiệm trên giếng thạch đều lớn hơn 10 mm.
Wind Tunnel Tests of a Two-Element Wingsail with Focus on Near-Stall Aerodynamics
Authors: Hillenbrand Antonia , Giovannetti Laura Marimon , Dhomé Ulysse , Kuttenkeuler Jakob 
Published: October 2024

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Modern wind propulsion systems on ocean-going cargo vessels require automated trimming. Rigid wingsail designs often incorporate more than one degree of freedom enabling to trim for optimal performance in all sailing conditions. A profound understanding of the aerodynamic behavior is the basis for any trimming strategy. The region around stall is of particular importance as this is where the largest lift but also potential hysteresis effects are expected. In the present research, a two-element wingsail (main wing and flap) was tested in wind tunnel experiments investigating the two available degrees of freedom: the orientation of the main wing to the inflow and the deflection of the flap. Aerodynamic loads were measured in dynamic actuation sequences over both degrees of freedom capturing stall and reattachment. The consistent data reveals two stall stages. In the region between the first and the second stall, when changing the direction of rotation, the flow is found to be reversible. The hysteresis loop is in this case smaller and reattachment occurs at larger angles compared to when both stall stages occur. This smaller hysteresis loop could be exploited in trimming. The second stall stage, however, is identified as detrimental both in the forces and the amount of required actuation to allow the flow to reattach. A considerate flap trim, i.e. the adjustment of the wingsail curvature, is suggested to avoid the second stall.

Keywords
Wind propulsion; Wind tunnel tests; Stall hysteresis; Two-element wing; Rigid wingsail; Trimming; Automation
Students' Behavior in the Learning Process Using Zoom Meeting Media: Problems and Solutions
Authors: Zaim Muhammad , Zakiyah Muflihatuz , Zaim Rifqi Aulia 
Published: October 2024

Recent digital technologies have increased the flexibility of learning. Online learning is now seen as a good alternative, not a force anymore. Among all online learning media that can aid, Zoom is an interactive online learning media mainly used by lecturers to carry out synchronous learning processes when offline lectures cannot be carried out. Using Zoom, lecturers and students can interact synchronously, like face-to-face learning in class. Many studies have been conducted to see the impacts of online learning on students’ learning behaviors using various media, yet studies on how students behave while learning using Zoom have not yet been explored in more detail. This research aims to reveal how students behave in the learning process by using Zoom in English classes through a survey study. Data were collected through a questionnaire delivered online to some 142 English Department students of Universitas Negeri Padang who experienced online learning. They voluntarily took part in this survey. Carrying quantitative analysis, the research showed that most students did not follow the Zoom-mediated learning process as well as they did face-to-face learning, which was carried out offline, for various reasons. Several positive and negative behaviors were found when implementing the learning process using Zoom. Therefore, for the learning process to run well, it is necessary to agree on the ethics of the learning process by using Zoom. The findings of this research can provide a reference for making conventional ethics of online learning using Zoom or other media.
Analisis Risiko K3 pada Aktivitas Pembuatan Pagar di Bengkel Las Makmur Jaya Kabupaten Cilacap
Authors: Sari Dyah Nur Indah , Saptadi Julian Dwi 
Published: October 2024

Manajemen risiko K3 merupakan usaha untuk mengelola risiko K3 untuk mencegah kecelakaan kerja secara sistematis dan terstruktur. Pencegahan risiko kecelakaan kerja dapat menggunakan metode HIRADC. Bengkel Las Makmur Jaya merupakan usaha bidang sektor informal yang bergerak dibidang fabrikasi. Selama proses pembuatan pagar berlangsung, terdapat beberapa aktifitas seperti penggerindaan, pengelasan, pengecatan. Tingkat kesadaran para pekerja dalam penggunaan APD dinilai masih kurang. Tujuan penelitian ini adalah menganalisis bahaya dan risiko K3 pada proses pembuatan pagar di Bengkel Las Makmur Jaya. Jenis penelitian merupakan penelitian kualitatif dengan metode penelitian deskriptif. Bahaya yang ditimbulkan saat proses pembuatan pagar ialah bahaya ergonomi, radiasi, listrik, mekanik, asap dan gas, fisika, kimiawi, api/panas,dan bahaya debu. Hasil penilaian risiko proses pembuatan pagar ialah terdapat 18 risiko rendah, 26 risiko sedang dan 21 risiko tinggi. Pengendalian yang telah dilakukan oleh Bengkel Las Makmur Jaya ialah pengendalian administratif dan penggunaan APD. Pembuatan pagar terdapat 4 tahapan, dengan jumlah tingkat risiko yang berbeda pada tiap tahapannya. Tahap pra-fabrikasi terdapat 2 risiko rendah, tahap fabrikasi 7 risiko rendah, 8 risiko sedang dan 5 risiko tinggi, tahap pemasangan pagar dengan 9 risiko rendah, 16 risiko sedang dan 15 risiko tinggi, tahap finishing 2 risiko sedang dan 1 risiko tinggi
Manajemen Risiko Keselamatan dan Kesehatan Kerja pada Pekerja di Pabrik Tahu Tugumulyo Sumatera Selatan
Authors: Mustakim Meliyanto Taufik 
Published: October 2024

Pabrik tahu Tugumulyo, Sumatera Selatan merupakan industri yang sudah beroperasi sejak tahun 2014 yang bergerak dibidang produksi tahu dan memiliki 4 orang pekerja. Selain menimbulkan dampak yang positif, pabrik tahu yang aktif beroperasi ini juga menimbulkan dampak yang negatif terutama bagi pekerja di sana. Di industri produksi makanan rentan terjadi kecelakaan yang menimpa pekerja dikarenakan potensi bahaya yang ada di lingkungan kerja dan berisiko mengakibatkan kecelakaan kerja. Berdasarkan hasil studi pendahuluan yang dilakukan pada tanggal 25 Maret 2022 dari hasil pengamatan ditemukan beberapa permasalahan, salah satunya pada saat bekerja mereka mengalami cidera ringan, terpleset dan terluka yang diakibatkan kurangnya hati-hati dalam bekerja serta kondisi lingkungan kerja yang terlihat tidak baik seperti lantai yang licin, tidak menggunakan Alat Pelindung Diri salah seperti Apron, sepatu boot dan sarung tangan. Sedangkan Sikap juga berpengaruh terhadap perilaku tidak aman karena kurangnya kepedulian pekerja terhadap keselamatan diri sendiri sehingga mudah terjadinya kecelakaan kerja. Jenis penelitian yang digunakan adalah penelitian kualitatif dengan desain penelitian deskriptif. Pendekatan penelitian yang digunakan ialah observasional. Proses penilaian risiko mengacu pada Construction Industry Standard 25:2018. Identifikasi risiko dilakukan dengan menggunakan metode Hazard Identification, Risk Assessment, and Risk Control (HIRARC). Metode ini dimulai dengan mengklasifikasikan aktivitas kerja, mengidentifikasi kemungkinan bahaya yang terjadi di tempat kerja kemudian dilanjutkan dengan penilaian risiko lalu memberikan rekomendasi pengendalian bahaya dan risiko sehingga diharapkan dapat meminimalisir tingkat risiko. Subjek pada penelitian kali ini berjumlah 3 orangpekerja. Pemilihan informan pada penelitian ini yaitu dipilih dengan menggunakan teknik Snowball Sampling. Penilaian risiko menggunakan metode Hazard Identification, Risk Assessment, and Risk Control pada proses produksi Tahu di Pabrik Tugumulyo terdapat 12 sumber bahaya tingkat low, 26 sumber bahaya tingkat medium dan 2 sumber bahaya tingkat high. Aktivitas kerja perebusan dan penggorengan memiliki sumber bayaha yang berada pada tingkat risiko high yaitu suhu lingkungan kerja yang tinggi, sementara sumber bahaya yang terdapat hampir disemua aktivitas kerja adalah lantai yang licin dan basah. Pada proses pembuatan Tahu di Pabrik Tahu Tugumulyo Sumatera Selatan terdapat 6 sumber bahaya yaitu physical hazard, mechanical hazard, ergonomic hazard, electricity hazard, sound hazard, dan vibration hazard. Pengendalian risiko sementara yang dapat diterapkan yaitu Engineering controls pada sebagian peralatan produksi serta penggunaan PPE controls berupa sepatu boot dan apron. Rekomendasi pengendalian yang dibuat pada manajemen risiko berupa Elimination, Substitution, Engineering controls, Administrative controls, dan Personal protective equipment (PPE).
A novel gene silencing strategy based on tobacco rattle virus in Hibiscus mutabilis
Authors: Sang Shiye , Liu Yiqiong , Li Xiu , Ma Jiao , Liu Xiaoli , Yang Yuanzhao 
Published: October 2024

Background
Hibiscus mutabilis L. is a popular regional characteristic plant in China, cultivated for its attractive flower colors, extended bloom time, and medicinal properties. To enhance molecular breeding and gene function studies, we conducted transcriptome analysis and identified valuable genes in previous research. Nonetheless, the current inefficient and labor-intensive transformation techniques have hindered their applications. Virus-induced gene silencing (VIGS) provides a precise and effective strategy for post-transcriptional down-regulation of endogenous gene expression.

Methods
We investigated the performance of tobacco rattle virus (TRV) as a tool for targeting and silencing the gene encoding the protein involved in chloroplast development, cloroplastos alterados 1 (altered chloroplast; CLA1), of H. mutabilis through Agrobacterium tumefaciens-mediated infiltration.

Results
By effectively suppressing the CLA1 gene associated with chloroplast development in H. mutabilis via the TRV-VIGS system, we have illustrated the inaugural implementation of VIGS in this species. Quantitative RT-PCR proved that HmCLA1 expression in agro-infiltrated plants was lower than in the mock-infiltrated (mock) and the control (CK) plants. Phenotypic observations corroborated the albino phenotype in leaves following successful HmCLA1 silencing.

Conclusions
Our study showcases TRV-VIGS as a potential gene silencing tool for H. mutabilis, facilitating functional genomics studies and molecular breeding efforts in this species.
A Comprehensive Review of Unmanned Aerial Vehicle (UAV) Sprayers Used in Modern Agriculture
Authors: Bharad N. B. , Vagadia V. R. , Lakhani A. L. , Khanpara B. M. , Dulawat M. S. 
Published: October 2024

Global demand for food is increasing daily due to increase in population growth. Hence to meet these food demands for the growing population crop productivity must be enhanced. Plant pests and diseases are major threats to crop productivity causing an annual reduction of 20 to 40% in global crop production. For management of these pest and diseases spraying using manual sprayers is quite laborious and also not precise. Further manual spraying is hazardous to farmer’s health, World Health Organization (WHO) reported one million incidences of illness as a result of manually application of insecticides to crop fields. As a result, new automated drone technology techniques were unveiled. This review examines the application of Unmanned Aerial Vehicle (UAV) sprayers in modern agriculture, highlighting their transformative role in enhancing crop management and increasing efficiency. UAV technology has emerged as a vital tool for precision agriculture, offering benefits such as targeted pesticide and fertilizer application, reduced labor costs, and minimized environmental impact. This paper discusses the various types of UAV sprayers, their operational mechanisms, and the advantages they provide over traditional methods. Additionally, we explore challenges associated with UAV adoption, including regulatory issues, technical limitations, and the need for operator training. The review emphasizes the future potential of UAV sprayers in sustainable agriculture, suggesting that continued advancements in technology and regulatory frameworks will further integrate UAVs into mainstream agricultural practices.
Adding stable carbon isotopes improves model representation of the role of microbial communities in peatland methane cycling
Authors: Deng Jia , McCalley Carmody K , Frolking Steve , Chanton Jeff , Crill Patrick , Varner Ruth , Tyson Gene , Rich Virginia , Hines Mark , Saleska Scott R. , Li Changsheng 
Published: May 2017

AbstractClimate change is expected to have significant and uncertain impacts on methane (CH4) emissions from northern peatlands. Biogeochemical models can extrapolate site‐specificCH4 measurements to larger scales and predict responses of CH4 emissions to environmental changes. However, these models include considerable uncertainties and limitations in representing CH4 production, consumption, and transport processes. To improve predictions of CH4 transformations, we incorporated acetate and stable carbon (C) isotopic dynamics associated with CH4 cycling into a biogeochemistry model, DNDC. By including these new features, DNDC explicitly simulates acetate dynamics and the relative contribution of acetotrophic and hydrogenotrophic methanogenesis (AM and HM) to CH4 production, and predicts the C isotopic signature (δ13C) in soil C pools and emitted gases. When tested against biogeochemical and microbial community observations at two sites in a zone of thawing permafrost in a subarctic peatland in Sweden, the new formulation substantially improved agreement with CH4 production pathways and δ13C in emitted CH4 (δ13C‐CH4), a measure of the integrated effects of microbial production and consumption, and of physical transport. We also investigated the sensitivity of simulated δ13C‐CH4 to C isotopic composition of substrates and, to fractionation factors for CH4 production (αAM and αHM), CH4 oxidation (αMO), and plant‐mediated CH4 transport (αTP). The sensitivity analysis indicated that the δ13C‐CH4 is highly sensitive to the factors associated with microbial metabolism (αAM, αHM, and αMO). The model framework simulating stable C isotopic dynamics provides a robust basis for better constraining and testing microbial mechanisms in predicting CH4 cycling in peatlands.
Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis
Authors: Schulert Grant S. , Minoia Francesca , Bohnsack John , Cron Randy Q. , Hashad Soah , KonÉ‐Paut Isabelle , Kostik Mikhail , Lovell Daniel , Maritsi Despoina , Nigrovic Peter A. , Pal Priyankar , Ravelli Angelo , Shimizu Masaki , Stanevicha Valda , Vastert Sebastiaan , Woerner Andreas , de Benedetti Fabrizio , Grom Alexei A. 
Published: May 2017

ObjectiveTo assess performance of the 2016 macrophage activation syndrome (MAS) classification criteria for patients with systemic juvenile idiopathic arthritis (JIA) who develop MAS while treated with biologic medications.MethodsA systematic literature review was performed to identify patients with MAS while being treated with interleukin (IL)‐1 and IL‐6 blocking agents. Clinical and laboratory information was compared to a large previously compiled historical cohort.ResultsEighteen publications were identified, and after removing duplicates, 35 patients treated with canakinumab and 49 patients with tocilizumab were available for analysis; 5 anakinra‐treated patients were excluded due to limited numbers. MAS classification criteria were less likely to classify tocilizumab‐treated patients as having MAS compared to the historical cohort or canakinumab‐treated patients (56.7%, 78.5%, and 84%, respectively; P < 0.01). Patients who developed MAS while treated with canakinumab trended towards lower ferritin at MAS onset than the historical cohort (4,050 versus 5,353 ng/ml; P = 0.18) but had no differences in other cardinal clinical or laboratory features. In comparison, patients who developed MAS while treated with tocilizumab were less likely febrile and had notably lower ferritin levels (1,152 versus 5,353 ng/ml; P < 0.001). Other features of MAS were more pronounced in patients treated with tocilizumab, including lower platelet counts, lower fibrinogen, and higher aspartate aminotransferase levels. Mortality rates for patients with MAS treated with tocilizumab or canakinumab were not significantly different from the historical cohort.ConclusionThese findings show substantial alterations in MAS features that may limit utility of defined criteria for diagnosis of systemic JIA patients treated with biologic agents.
Coordinating Biointeraction and Bioreaction of a Nanocarrier Material and an Anticancer Drug to Overcome Membrane Rigidity and Target Mitochondria in Multidrug‐Resistant Cancer Cells
Authors: Zhang Rui Xue , Li Lily Yi , Li Jason , Xu Zhensong , Abbasi Azhar Z. , Lin Lucy , Amini Mohammad A. , Weng Wei Yu , Sun Yu , Rauth Andrew M. , Wu Xiao Yu 
Published: May 2017

AbstractMultidrug resistance (MDR) is a main cause of chemotherapy failure in cancer treatment. It is associated with complex cellular and molecular mechanisms including overexpression of drug efflux transporters, increased membrane rigidity, and impaired apoptosis. Numerous efforts have been made to overcome efflux transporter‐mediated MDR using nanotechnology‐based approaches. However, these approaches fail to surmount plasma membrane rigidity that attenuates drug penetration and nanoparticle endocytosis. Here, a “one‐two punch” nanoparticle approach is proposed to coordinate intracellular biointeraction and bioreaction of a nanocarrier material docosahexaenoic acid (DHA) and an anticancer prodrug mitomycin C (MMC) to enhance mitochondrion‐targeted toxicity. Incorporation of DHA in solid polymer‐lipid nanoparticles first reduces the membrane rigidity in live cancer cells thereby increasing nanoparticle cellular uptake and MMC accumulation. Subsequent intracellular MMC bioreduction produces free radicals that in turn react with adjacent DHA inducing significantly elevated mitochondrial lipid peroxidation, leading to irreversible damage to mitochondria. Preferential tumor accumulation of the nanoparticles and the synergistic anticancer cytotoxicity remarkably inhibit tumor growth and prolonged host survival without any systemic toxicity in an orthotopic MDR breast tumor model. This work suggests that combinatorial use of biophysical and biochemical properties of nanocarrier materials with bioreactive prodrugs is a powerful approach to overcoming multifactorial MDR in cancer.
Porous Carbon Composites for Next Generation Rechargeable Lithium Batteries
Authors: Liu Hao , Liu Xiaoxue , Li Wei , Guo Xin , Wang Yong , Wang Guoxiu , Zhao Dongyuan 
Published: May 2017

AbstractRechargeable lithium batteries have attracted great attention as next generation power systems for electric vehicles (EVs). Lithium ion batteries, lithium–sulfur batteries, and lithium–oxygen batteries are all suitable to be the power systems for next generation EVs, but their power densities and cycling performance still need to be improved to match the requirements of practical EVs. Thus, rational design and controllable synthesis of electrode materials with unique microstructure and outstanding electrochemical performance are crucially desired. Porous carbon‐based composites have many advantages for energy storage and conversion owing to their unique properties, including high electronic conductivity, high structural stability, high specific surface area, large pore volume for efficient electrolyte flux, and high reactive electrode materials with controllable size confined by porous carbon frameworks. Therefore, porous carbon composites exhibit excellent performance as electrode materials for lithium ion batteries, lithium–sulfur batteries, and lithium–oxygen batteries. In this review, we summarize research progress on porous carbon composites with enhanced performance for rechargeable lithium batteries. We present the detailed synthesis, physical and chemical properties, and the innovation and significance of porous carbon composites for lithium ion batteries, lithium–sulfur batteries, and lithium–oxygen batteries. Finally, we conclude the perspectives and critical challenges that need to be addressed for the commercialization of rechargeable lithium batteries.