bluuebunny/crossref_metadata_2025_split huggingface dataset:
The crystal structure of veenite
Authors: Topa Dan , Makovicky Emil 
Published: March 2017

AbstractThe crystal structure of veenite is reported for the first time from a sample from the type locality of Madoc (Ontario, Canada). It has been solved and refined by X-ray single-crystal diffraction on the basis of 4973 observed reflections (withFo> 4σ(Fo)) with a finalR1= 0.0396. Veenite is monoclinicP21, with unit-cell parametersa= 8.429(2),b= 26.069(5),c= 8.962(2) Å, β = 117.447(2)o. The bulk veenite composition is Ag0.15Pb16.029Sb8.836As6.99S39.95(forZ= 1) corresponding to N = 4.09 (Me8NS8N + 8, theoretical value is 4.0), with the percentage of the Ag-(As,Sb) substituted end-member only equal to 3.51 mol.%, i.e., a nearly pure Pb-Sb-As sulfosalt. The crystal structure is typical for the N = 4 sartorite homologue, with zig-zag walls of trigonal coordination prisms of Pb which separate slabs of diagonally oriented double-layers populated by Sb and As with partial Pb substitution. Orientation of three-membered crankshaft chains formed by strong (As,Sb) – S bonds on the two surfaces of double-layers differs substantially from that in dufrénoysite, which is a pure Pb-As (N = 4) sulfosalt.
PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma
Authors: Nayak Lakshmi , Iwamoto Fabio M. , LaCasce Ann , Mukundan Srinivasan , Roemer Margaretha G. M. , Chapuy Bjoern , Armand Philippe , Rodig Scott J. , Shipp Margaret A. 
Published: March 2017

Key Points
Genetic analysis reveals frequent 9p24.1/PD-L1/PD-L2 copy-number alterations and increased expression of the PD-1 ligands in PCNSL and PTL. PD-1 blockade with nivolumab demonstrated activity in patients with relapsed/refractory PCNSL and PTL.
From top to bottom: midkine and pleiotrophin as emerging players in immune regulation
Authors: Sorrelle Noah , Dominguez Adrian T A , Brekken Rolf A 
Published: March 2017

Abstract
Cytokines are pivotal in the generation and resolution of the inflammatory response. The midkine/pleiotrophin (MK/PTN) family of cytokines, composed of just two members, was discovered as heparin-binding neurite outgrowth-promoting factors. Since their discovery, expression of this cytokine family has been reported in a wide array of inflammatory diseases and cancer. In this minireview, we will discuss the emerging appreciation of the functions of the MK/PTN family in the immune system, which include promoting lymphocyte survival, sculpting myeloid cell phenotype, driving immune cell chemotaxis, and maintaining hematopoiesis.
Fiscal Decentralization and Public Spending: Evidence from Heteroscedasticity-Based Identification
Authors: Herwartz Helmut , Theilen Bernd 
Published: March 2017

Abstract
We analyse the instantaneous relation between public spending and expenditure decentralization by means of a novel identification scheme suggested in Lewbel (2012). Our cointegration, error-correction approach indicates that expenditure decentralization impacts negatively on total public spending and most of its subcategories.
Keymorph analysis, or how morphosyntax informs discourse
Authors: Fidler Masako , Cvrček Václav 
Published: March 2017

Abstract
This paper introduces keymorph analysis (KMA), a new extension of the discourse-probing technique of keyword analysis (KWA). While KWA focuses on lexicon and provides a key predominantly to textual topics and their semantic associations, KMA focuses on morphosyntactic features and captures more general characteristics of texts as wholes. Speeches by Czech(oslovak) presidents and corpus of contemporary written Czech SYN2015 are used to illustrate readers’ perception of situations and their participants in these texts. The paper also shows that different levels of morphosyntax facilitate interpretation of discourse: ideological differences can be observed with higher-level morphosyntactic features (parts of speech), while differences in speaker style are observable with lower-level morphosyntactic features (case, number, person, and their combinations).
Mycosynthesis of nanoparticles using edible and medicinal mushrooms
Authors: Owaid Mustafa Nadhim , Ibraheem Ibraheem Jaleel 
Published: March 2017

AbstractThis review distinguishes myco-nanotechnology using metallic nanoparticles (meta-NPs) synthesized from edible mushroom matter. Green chemistry approaches were attempted to myco-synthesize meta-NPs (viz., Ag-NP, Au-NP, Se-NP, CdS-NP, Fe-NP, Pa-NP, and ZnS-NP) via different routes using edible mushrooms and have been tested toward 79% biomedical and 21% industrial applications. Biomaterials were used as biofactors to form metallic NPs. In mushroom science, mycomaterials of mushrooms were used at different percentages to mycosynthesize in an ecofriendly/green way; mycomaterials such as crude extracts of basidocarp (53%), mycelial extract or free cell filtrate (28%), in crude form or in purified form such as polysaccharides at different percentages; 9% (especially glucan), proteins/enzymes (7%) and polysaccharides protein complex (3%) as new research lines. Generally, in this field of mushroom nanoparticles about 84% of mycosynthesized NPs using mushrooms are placed outside the fungal cell (extracellular) and 16% are intracellular in the mushroom hyphae. The knowledge of the performance and influence of meta-NPs in edible mushrooms has developed in the last 10 years. Generally, while
Kinetics of green solid-liquid extraction of useful compounds from plant materials: kinetics coefficients and modeling
Authors: Simeonov Evgeni , Yaneva Zvezdelina , Chilev Chavdar 
Published: March 2017

AbstractA mathematical model for modeling solid-liquid extraction from plants was developed. Two extraction systems, System INicotiana tabacumL.-waterand System IIGeranium sanguineumL.-water, were investigated. The effect of agitation rate on the mode of the extraction process was studied, as the limit values in the case of internal diffusion for System I and System II were determined. The kinetics of extraction for both systems at determined technological parameters (temperature and solid/liquid ratio) was experimentally investigated. The values of the partial mass transfer coefficient,k, were determined by the Regular regime method. A four-parameter empirical model for prediction of the effective diffusivity,Deff, was also presented. The model adequacy is verified with the experimental data and shows very good coincidence.
Anti-inflammatory activity of Elaeagnus angustifolia fruit extract on rat paw edema
Authors: Motevalian Manijeh , Shiri Mehdi , Shiri Saeedeh , Shiri Zahra , Shiri Hadi 
Published: March 2017

Abstract

Background:
The Elaeagnus angustifolia fruit has been traditionally used in Iranian herbal medicine to treat diarrhea and rheumatoid arthritis. In the present study, the effects of E. angustifolia fruit extract on the acute and chronic phases of formalin-induced rat paw edema were examined.

Methods:
The acute and chronic anti-inflammatory effects of E. angustifolia fruit extract were investigated through the subcutaneous injection of 100 μL of formalin (2.5%) into a rat’s hind paw. Thirty minutes before the procedure, the experimental groups were treated intraperitoneally with hydroalcoholic fruit extracts of E. angustifolia (concentrations of 100, 300, 700, and 1000 mg/kg); sodium salicylate (SS, 400 mg/kg) and distilled water were used as positive and negative control groups, respectively. Treatment with SS and the fruit extracts were performed daily for 8 days, and the degree of edema was measured by using mercury plethysmometer and digital caliper.

Results:
In the acute anti-inflammatory study, the extract showed a significant anti-inflammatory effect in a dose-dependent manner. The results of 1000 mg/kg of the extract was significantly different compared with the negative control group (p<0.05) and was comparable to sodium salicylate (p<0.05). Results from the chronic study suggested that E. angustifolia extract significantly reduced paw edema and inflammation in a dose-dependent manner. The results also showed that the measurement by digital caliper and mercury plethysmometer were both reliable and might be applied interchangeably (p<0.01). Phytochemical tests indicated that the hydroalcoholic fruit extract of E. angustifolia was positive for cardiac glycosides, flavonoids, terpenoids, and saponins.

Conclusions:
Based on our findings, the E. angustifolia fruit extract probably has acute and chronic anti-inflammatory activities to support its applications in folk medicine.
Ontology Concept-Based Management and Semantic Retrieval of Satellite Data
Authors: Abburu Sunitha , Dube Nitant 
Published: March 2017

AbstractSeveral satellite data receiving and distributing centers across the world support data storage, processing, and retrieval based on satellite, sensor, product, latitude, longitude, date and time, etc. These systems address queries on satellite products that are mostly high-level concepts. A more sophisticated retrieval system that supports ontological concepts, subconcepts, and concept hierarchical queries delivers refined results that broaden the scientific horizon of the application domain. To achieve this, the current research designed and implemented an ontology concept-based satellite data management and retrieval methodology. This enhances the performance of the satellite data retrieval system and supports semantic queries. The performance of the retrieval system depends upon the strategy followed to maintain domain ontologies and satellite data instances. Three ontology-based satellite data management strategies are discussed, and their performance was evaluated by taking real and benchmark metrics. A semantic query set of 25 queries was chosen covering various concepts, subconcepts, and concept hierarchical-related queries that involve various SPARQL query constructs. The test bed is taken from real-time satellite data received from Kalpana-1 of various sizes of triple stores.
The significance of strong ion gap for predicting return of spontaneous circulation in patients with cardiopulmonary arrest
Authors: Kaneko Minoru , Hagiwara Shuichi , Aoki Makoto , Murata Masato , Nakajima Jun , Oshima Kiyohiro 
Published: March 2017

Abstract
Useful parameters that can predict return of spontaneous circulation (ROSC) in patients with cardiopulmonary arrest (CPA) have not been established. We previously reported the usefulness of anion gap (AG) and albumin-corrected anion gap (ACAG) calculated from a blood sample obtained on arrival at the hospital for the prediction of ROSC. Otherwise, it has been reported that strong ion gap (SIG), which shows the difference between the levels of fully dissociated cations and anions in the serum, is useful to predict the prognosis of critically ill patients.
This was a prospective and observational clinical study. Patients with CPA transferred to the emergency department of our hospital between January 2013 and December 2014 were evaluated. Patients were divided into two groups: patients who obtained ROSC [ROSC(+) group] and those who did not [ROSC(−) group]. We compared AG, ACAG and SIG between the two groups.
A total of 170 patients were enrolled. Fifty patients were included in the ROSC(+) group, and the remaining 120 in the ROSC(−) group. Both AG and ACAG were significantly better in the ROSC(+) group; however, there was no significant difference in SIG between the two groups. The area under the receiver operating characteristic curves (AUC) for ROSC of both AG and ACAG were almost the same (0.72 and 0.708, respectively); the AUC of SIG (0.57) was inferior to those of AG and ACAG.
Our results suggest that AG and ACAG can better predict ROSC following cardiopulmonary resuscitation (CPR) compared with SIG.
Quadratic Convective Flow of a Micropolar Fluid along an Inclined Plate in a Non-Darcy Porous Medium with Convective Boundary Condition
Authors: RamReddy Ch. , Naveen P. , Srinivasacharya D. 
Published: March 2017

AbstractThe objective of the present study is to investigate the effect of nonlinear variation of density with temperature and concentration on the mixed convective flow of a micropolar fluid over an inclined flat plate in a non-Darcy porous medium in the presence of the convective boundary condition. In order to analyze all the essential features, the governing non-dimensional partial differential equations are transformed into a system of ordinary differential equations using a local non-similarity procedure and then the resulting boundary value problem is solved using a successive linearisation method (SLM). By insisting the comparison between vertical, horizontal and inclined plates, the physical quantities of the flow and its characteristics are exhibited graphically and quantitatively with various parameters. An increase in the micropolar parameter and non-Darcy parameter tend to increase the skin friction and the reverse change is observed in wall couple stress, mass and heat transfer rates. The influence of the nonlinear concentration parameter is more prominent on all the physical characteristics of the present model, compared with that of nonlinear temperature parameter.
Velocity and thermal slip effects on MHD third order blood flow in an irregular channel though a porous medium with homogeneous/ heterogeneous reactions
Authors: Gnaneswara Reddy M. 
Published: March 2017

AbstractThis communication presents the transportation of third order hydromagnetic fluid with thermal radiation by peristalsis through an irregular channel configuration filled a porous medium under the low Reynolds number and large wavelength approximations. Joule heating, Hall current and homogeneous-heterogeneous reactions effects are considered in the energy and species equations. The Second-order velocity and energy slip restrictions are invoked. Final dimensionless governing transport equations along the boundary restrictions are resolved numerically with the help of NDsolve in Mathematica package. Impact of involved sundry parameters on the non-dimensional axial velocity, fluid temperature and concentration characteristics have been analyzed via plots and tables. It is manifest that an increasing porosity parameter leads to maximum velocity in the core part of the channel. Fluid velocity boosts near the walls of the channel where as the reverse effect in the central part of the channel for higher values of first order slip. Larger values of thermal radiation parameter
The Evolving Definition of the Term “Gene”
Authors: Portin Petter , Wilkins Adam 
Published: March 2017

AbstractThis paper presents a history of the changing meanings of the term “gene,” over more than a century, and a discussion of why this word, so crucial to genetics, needs redefinition today. In this account, the first two phases of 20th century genetics are designated the “classical” and the “neoclassical” periods, and the current molecular-genetic era the “modern period.” While the first two stages generated increasing clarity about the nature of the gene, the present period features complexity and confusion. Initially, the term “gene” was coined to denote an abstract “unit of inheritance,” to which no specific material attributes were assigned. As the classical and neoclassical periods unfolded, the term became more concrete, first as a dimensionless point on a chromosome, then as a linear segment within a chromosome, and finally as a linear segment in the DNA molecule that encodes a polypeptide chain. This last definition, from the early 1960s, remains the one employed today, but developments since the 1970s have undermined its generality. Indeed, they raise questions about both the utility of the concept of a basic “unit of inheritance” and the long implicit belief that genes are autonomous agents. Here, we review findings that have made the classic molecular definition obsolete and propose a new one based on contemporary knowledge.
Ages and Stages Questionnaire at 3 Years for Predicting IQ at 5–6 Years
Authors: Charkaluk Marie-Laure , Rousseau Jessica , Calderon Johanna , Bernard Jonathan Y , Forhan Anne , Heude Barbara , Kaminski Monique ,   on behalf of the EDEN Mother–Child Cohort Study Group
Published: March 2017

OBJECTIVES:
To assess the predictive value of the 36-month Ages & Stages Questionnaire (ASQ) score for IQ score at age 5 to 6 years in the general population and to identify factors associated with IQ &lt;85 once the ASQ score is taken into account.

METHODS:
Data were collected from 939 children enrolled in a population-based prospective cohort study. Developmental outcomes at 36 months were assessed via the ASQ and at 5 to 6 years via the Wechsler Preschool and Primary Scale of Intelligence. The ASQ threshold was identified via the receiver operating characteristic curve. Additional predictive factors to obtain an IQ &lt;85 were investigated, and their interaction with ASQ score was studied.

RESULTS:
Sixty-nine children (7.3%) had an IQ &lt;85. A 36-month ASQ score threshold of 270 was optimal to identify children with an IQ &lt;85 at 5 to 6 years, with a 0.77 ± 0.11 sensitivity and 0.68 ± 0.03 specificity. Maternal educational level and occupational activity at the time of ASQ completion were associated with the risk of an IQ &lt;85 at a given ASQ level. In the multivariate model, no interaction between the studied factors and ASQ score reached significance.

CONCLUSIONS:
In the general pediatric population, 36-month ASQ parental reports could be used to identify children at later risk of cognitive delay. Low maternal education level should also be considered as a major risk factor for lower IQ in preschool children regardless of ASQ score.
Estado nutricional antropométrico e associação com pressão arterial em crianças e adolescentes: um estudo populacional
Authors: Da Silva Souza Letícia , Cavalheiro do Espírito Santo Rafaela , Franceschi Camila , De Avila Cassiane , Centenaro Suellienn , Soares dos Santos Gisselle 
Published: March 2017

Aims: To evaluate the nutritional status of children and adolescents by anthropometric indicators and to evaluate the association of these results with blood pressure. Methods: Children and adolescents between four and 19 years of age from rural and urban schools of a municipality of Rio Grande do Sul were included in this study. Those who refused (or whose parents refused) to participate or did not sign the consent form, or in whom it was not possible to carry out the anthropometric or blood pressure measurements, were excluded. Weight, height, waist circumference, skin folds and blood pressure were measured, and the body mass index was calculated. Data were described by mean, standard deviation, amplitude of variation, absolute and relative frequencies. Stratification by gender, body mass index and central obesity was performed to analyze the influence of these on the other variables. Pearson's Chi-square was used to evaluate the associations. The level of significance was p<0.05.Results: At the time of data collection, 7,082 children and adolescents within the age group were enrolled in the municipal schools, and they were invited to participate. After applying the exclusion criteria, 5,936 children/adolescents were included in the study. The sample presented prevalence of overweight of 30.3%, central obesity 31.1% and excess body fat 8.7%. Overweight was higher in children from private schools (44.1%) than in state schools (29.5%) and municipal schools (29.9%) (p<0.001). There were statistically significant associations of high blood pressure with overweight, obesity, and central obesity (p<0.001).Conclusions: Prevalence of overweight was high and hypertension was associated with overweight, obesity and central obesity in children and adolescents of the studied population.
Exercise addiction risk and health in male and female amateur endurance cyclists
Authors: Mayolas-Pi Carmen , Simón-Grima Javier , Peñarrubia-Lozano Carlos , Munguía-Izquierdo Diego , Moliner-Urdiales Diego , Legaz-Arrese Alejandro 
Published: March 2017

Background and aims
To determine the relationship between the risk of exercise addiction (REA) and health status in amateur endurance cyclists.

Methods
In 859 (751 men and 108 women) cyclists and 718 inactive subjects (307 men and 411 women), we examined the REA (Exercise Addiction Inventory), training status (volume, frequency, experience, and performance), socioeconomic status, quality of life (QoL) (SF-12), quality of sleep (Pittsburgh Sleep Quality Index), anxiety and depression (Hospital Anxiety and Depression Scale), and cardiometabolic risk: body mass index, physical activity (International Physical Activity Questionnaire), physical condition (International Fitness Scale), adherence to the Mediterranean diet (Mediterranean Diet Adherence Screener), alcohol and tobacco consumption.

Results
In total, 17% of the cyclists showed evidence of REA and 83% showed low REA. REA occurred independent of age, sex, training, and socioeconomic status (all ps > .05). Regardless of REA, the cyclists displayed a better physical QoL and a lower cardiometabolic risk than the inactive subjects (all ps < .05). The cyclists with REA displayed worse values of mental QoL, quality of sleep, and anxiety than cyclists with low REA (all ps < .05). The REA group had better values of mental QoL and anxiety and similar values of quality of sleep than the inactive subjects. The differences in mental QoL between the REA and low REA groups were significantly greater in women (p = .013). There was no Addiction × Sex interaction in the other analyzed variables.

Conclusion
Our results suggest that an increased prevalence of REA limits the benefits that amateur endurance cycling has on mental health and quality of sleep.
PROGRESIVISME JOHN DEWEY DAN PENDIDIKAN PARTISIPATIF PERSPEKTIF PENDIDIKAN ISLAM
Authors: Mualifah Ilun 
Published: March 2017

<p>BAHASA INDONESIA:</p><p>Artikel ini berisi tentang konsep pendidikan partisipatif yang dikaitkan dengan konsep progresivisme pendidikan John Dewey, dan kemudian dikaji dalam perspektif pendidikan Islam. Konsep pendidikan partisipatif dalam progresivisme pendidikan John Dewey merupakan konsep pendidikan yang mengacu pada teori-teori John Dewey yang berpijak pada asas-asas progresivitas. Asas progresivitas berprinsip pada sikap optimistis dalam memandang kemajuan peserta didik dalam proses pendidikannya. Konsep progresivisme pendidikan John Dewey yang megandung asas pendidikan partisipatif dalam pandangan pendidikan Islam bisa dipertegas: bahwa terdapat beberapa aspek kesesuaian (terutama dalam hal kemanfaatan yang bersifat duniawi), dan terdapat banyak aspek perbedaan yang sangat prinsip (terutama mengenai hal-hal yang bersifat metafisik-spiritual). Dengan demikian, ketika akan menerapkan asas partisipatif dalam konsep pendidikan Dewey di dalam kehidupan umat Islam, perlu difilter terlebih dahulu dengan kacamata nilai-nilai Islam. Apabila tidak bertentangan dengan nilai-nilai Islam, maka perlu diterapkan; namun apabila bertentangan dengan nilai-nilai Islam, maka tidak perlu diterapkan (cukup dijadikan pengetahuan saja).</p><p> </p><p>ENGLISH:</p><p>This article discusses about participative education related to education progressivism concept by John Dewey, and then it is examined on Islamic studies perception. Participative education concept on John Dewey’s education progressivism is education concept that refers to John Dewey’s theories that bring up progressive principles. The progressive principles base on optimistic attitude on viewing the progress of learners’ learning process. The education progressivism concept by John Dewey contains participative education principles; it can be strengthened on Islamic education view that there are some compatibility aspects (especially in worldly usefulness), and there are many differences based on principles (especially in metaphysic-spiritual thing). Therefore, when Muslims will implement participative principles on Dewey’s educational concept in their life, they need to filter it based on Islamic views. If it does not contradict to Islamic views, it should be implemented on their life. Nevertheless, if it opposes Islamic views, it should not be implemented on their life (it is enough for them to know it as knowledge).</p>