bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of Carbapenemase Genes among Carbapenem-Resistant Klebsiella pneumoniae Isolates from the Patients in Najaf, Iraq
Authors: Mohanna Zahraa A. , AL-Yasseen Ahlam Kadhum 
Published: September 2024

Abstract

Background:
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a global threat, causing serious community- and hospital-acquired infections with limited treatment options. Understanding the local epidemiology of CRKP is crucial for guiding antimicrobial stewardship and infection control measures. This study aimed to investigate the phenotypic characteristics, antimicrobial resistance profiles, and carbapenemase genes among CRKP isolates from the patients in Najaf, Iraq.

Methods:
This cross-sectional research was performed at diverse hospitals and centers in Najaf, Iraq, from September 2023 to March 2024. The study was approved by the Ethics Committee of Kufa University. CRKP isolates were collected from various health-care facilities and tested for hypermucoviscosity, antimicrobial susceptibility, and carbapenemase production using phenotypic methods. The presence of carbapenemase genes (blaNDM, blaVIM, blaKPC, blaOXA-48, blaOXA-23, and blaOXA-51) was examined by polymerase chain reaction.

Results:
Of the 27 CRKP isolates, 9 (33.3%) exhibited a hypermucoviscous phenotype. Regarding antimicrobial resistance, 12 (44.4%) were multidrug resistant, 14 (51.9%) were extensively drug resistant, and 1 (3.7%) was pandrug resistant. Phenotypic carbapenemase production was detected in 5 (18.5%) and 11 (40.7%) isolates by the modified Hodge test and E-test metallo-β-lactamase strips, respectively. Molecular analysis revealed that all CRKP harbored the blaOXA-51 gene, whereas blaNDM, blaOXA-23, and blaVIM were detected in 70.4%, 40.7%, and 11.1% of the isolates, respectively. Neither blaKPC nor blaOXA-48 genes were found. In addition, 22 (81.5%) isolates carried multiple carbapenemase genes.

Conclusions:
The high prevalence of blaOXA-51 and blaNDM carbapenemases, along with the high rates of multidrug resistance among CRKP isolates in Najaf, Iraq, are alarming. This necessitates the immediate implementation of effective antimicrobial stewardship and infection control measures to prevent the further spread of these difficult-to-treat pathogens.
Comparison of muscle response in patients treated with rigid and flexible fixed functional appliances
Authors: Saini Ruchi , Batra Puneet , Saini Nidhi , Punia Komal , Shair Tanjula , Raza Monis 
Published: September 2024

AIM:
The present study was undertaken to evaluate and compare muscle activity after the treatment with rigid and flexible fixed functional appliance.

MATERIAL AND METHOD:
The study was conducted on 14 skeletal Class II malocclusion patients in the age group of 13–17 years, divided into two groups comprising 7 patients in each group. Group I was treated with a rigid fixed functional appliance (MPA IV), and Group II was treated with a flexible fixed functional appliance (Churro Jumper). Masseter and anterior temporalis muscle activities were recorded using needle electromyography (EMG) at postural rest, saliva swallowing, and clenching during five intervals (T0 to T4) during fixed functional appliance treatment. Unpaired t-test, Mann–Whitney U, and Wilcoxon sign rank test were applied for statistical analysis, and a P value of <.05 was considered statistically significant.

RESULTS:
Group I (MPA IV) showed a significant increase in EMG activity during postural rest position (P = 0.003, P = 0.001), swallowing (P = 0.013, P = 0.005), and clenching (P = 0.001, P = 0.002) in masseter and anterior temporalis muscle, respectively. Group II (Churro jumper) also showed a significant increase in EMG activity during postural rest position (P = 0.000, P = 0.000), swallowing (P = 0.001, P = 0.000), and clenching (P = 0.001, P = 0.000) in masseter and anterior temporalis muscle, respectively.

CONCLUSION:
Both rigid (MPA IV) and flexible (Churro Jumper) fixed functional appliances caused a significant increase in EMG activity of masseter and anterior temporalis muscle during postural rest position, swallowing, and clenching in 6 months of the observation period, but the flexible appliance (Churro Jumper) showed more significant increase.
Meniscus root tears: what is the hype?
Authors: Wang Ming , Lee Dave Yee Han 
Published: September 2024

Abstract
Meniscus root tears are increasingly being studied due to their importance in meniscus function. Meniscus root tears can increase the joint contact pressure significantly, similar to a total meniscectomy. This may cause rapid progression of joint degeneration and produce inferior clinical outcome. Historically, they were treated with partial meniscectomy, which did not change the natural history. New repair techniques such as transtibial pull-out repair and suture anchor repair have improved the clinical outcome. This review article summarises the anatomy of the meniscus, the pathology of meniscus root tears and different repair techniques with their clinical outcomes.
PENGARUH PENERAPAN AKUNTANSI BERBASIS AKRUAL, GOOD GOVERNANCE, DAN PENGAWASAN PENGELOLAAN KEUANGAN TERHADAP PENCEGAHAN FRAUD PADA KEUANGAN DAERAH
Authors: Nafisah Maya Yulia , Witono Banu 
Published: September 2024

This study aims to analyze the effect of accrual-based accounting implementation, good governance, and financial management supervision on fraud prevention in regional finances. This research method is quantitative with the type of causality research. The data collection technique used by researchers in this study was a questionnaire method. The population in this study were subjects related to the research that the authors conducted at the secretariat of the Surakarta Privy Council. The sampling criteria set are employees or structural officials of the finance department who are in the secretariat of the Surakarta Keresidenan council. The sampling technique used is purposive sampling technique. The data source used by this researcher is primary data. Data analysis techniques are measured on a Likert scale using SPSS 20 software with data quality tests, classical assumption tests, and hypothesis testing. The results of this study are that the application of accrual-based accounting has a significant effect on fraud prevention both partially and simultaneously. Good governance has a significant effect on fraud prevention. Financial management supervision has no effect on fraud prevention
ANALISIS KELAYAKAN FINANSIALUSAHA TANI KOPI ARABIKA DI DESA MASOSO KECAMATAN BAMBANG KABUPATEN MAMASA
Authors: Pratama Irwan , Idrus Mukhammad , Sahade Sahade 
Published: September 2024

This study aims to determine the Financial Feasibility of Arabica Coffee Farming Business in Masoso Village, Bambang District, Mamasa Regency. This research is an analysis of financial feasibility as a single variable. The source of data in this study is data collected through interviews and documentation studies. Based on the type of data needed, in this study, the participants were coffee farmers in Masoso Village. Data collection was carried out using documentation and interview techniques. Data analysis is carried out by quantative descriptive analysis. The data analysis used is Usaahatani Cost (fixed costs and variable costs), and calculates the total production and income of farmers. Then calculate the difference between revenue and cost, then a financial feasibility analysis is carried out to find out whether the farming business is feasible or not, namely B/C ratio, R/C ratio and L/R. The results of this study show that the characteristics of coffee farmers such as gender (male and female), age of coffee farmers are said to be productive, education level of formal and non-formal coffee farmers, the number of dependents of family members is at most 1 person, the land area of arabica coffee farmers is at most 9 people with an area of 0.5-1 Ha and for the status of coffee land ownership, which is their own. The results of the financial feasibility of arabica coffee farming R/C Ratio of 4,03, B/C of 3,03 can be said to be feasible, the resulting production profit of Rp 5.204.034 is said to be feasible, because it makes a profit
ANALISIS EFEKTIVITAS PENDAMPINGAN KONSULTAN PAJAK DALAM PENYELESAIAN KASUS PERPAJAKAN KLIEN
Authors: Aliefah Nur Azizatul , Djasuli Mohamad 
Published: September 2024

This study aims to analyze the effectiveness of tax consultant assistance in resolving client tax cases at the Accounting Services Office (KJA) in Bojonegoro. This qualitative research uses a case study approach at KJA Lilis Ardini. Using qualitative data analysis, it was found that tax consultants have an important impact on clients in resolving tax problems, such as late payment and tax reporting. Key factors that affect the effectiveness of tax consultant assistance include the mentoring routine, good cooperation between consultants and clients, client honesty, and client awareness of the importance of tax compliance. The success of resolving tax cases is measured by the absence of complaints from the Tax Office and the sustainability of the client-consultant partnership. Although it has only been operating for one year, KJA Lilis Ardini has shown consistency in providing effective services to clients, without any significant changes in the approach or strategy used
COMPETÊNCIAS DIGITAIS NA APRENDIZAGEM DA LÍNGUA PORTUGUESA: INTEGRAR A ALFABETIZAÇÃO DIGITAL COM O ENSINO TRADICIONAL DA LÍNGUA PORTUGUESA PARA PREPARAR OS ALUNOS PARA A COMUNICAÇÃO NO MUNDO DIGITAL
Authors: Giovanelli Roberta Preissler Marcolino , Coutinho Diógenes José Gusmão 
Published: September 2024

O presente tem o intuito de analisar o processo que o individuo faz para atingir um desenvolvimento intelectual, social através das habilidades desenvolvidas em seu processo escolar e em seu meio de convivência, pensando em contribuir com um bom desenvolvimento através do letramento digital em junção com ensino tradicional da língua portuguesa. Nessa perspectiva, busca-se evidenciar de que forma a alfabetização digital desempenha as capacidades múltiplas do indivíduo em seu processo educacional, social e cultural para o preparo dos alunos para a comunicação no mundo digital. O tema foi escolhido por ser dinâmico e atual, sem perder a verdadeira essência da sede do conhecimento e do aprendizado. As capacidades múltiplas do indivíduo são desenvolvidas através do seu contato diariamente com diferentes tipos de textos, sejam eles impressos ou digitais, caracterizados como gêneros textuais, com estrutura verbal ou não verbal. Conclui-se que, embora o ensino tradicional da língua portuguesa necessite que seja dado continuidade, é possível e benéfico a integração com a alfabetização digital.
Postoperative Supine Sleeping Position Following Total Knee Arthroplasty Decreases Knee Flexion Contractures
Authors: Zondervan Robert L. , Riggle Patrick K. , Cien Adam J. , Penny Philip C. , Cochran Jason M. 
Published: September 2024

Background Total knee arthroplasty (TKA) is an orthopaedic operation that improves quality of life and reduces pain in patients with disabling arthritis of the knee. One commonly recognized postoperative complication is flexion contracture of the knee. While early physical therapy and range of motion (ROM) exercises have helped improve ROM postoperatively, flexion contractures still remain a significant postoperative complication of TKA. This study evaluated postoperative sleeping position and its effect on terminal knee extension and ROM following primary TKA. We hypothesized that patients who slept in the supine position would achieve earlier knee extension and ROM when compared to those in the lateral recumbent position. Methods A total of 150 consecutive primary total knee arthroplasties (TKAs) were conducted by a single surgeon (JMC). Prospective data collection included assessments of preoperative range of motion (ROM), postoperative ROM, patient-reported outcome measures, and sleeping positions. Functional outcomes and patient-reported measures were compared between pre- and postoperative phases, as well as across different sleeping position groups. Results Postoperative follow up was a mean of 29.6 days. Mean postoperative terminal extension ROM at one month was 2.98 degrees in the supine group versus 6.03 degrees in the lateral group (P < 0.001). Overall, there was significant improvement in patient reported outcome measures (WOMAC, Oxford, and pain) after surgery, but no difference existed between sleeping groups. For knee extension, a two-way ANOVA revealed that there was a statistically significant interaction between the effects of surgery and sleep position (p = 0.0053). Conclusions Our results demonstrate that sleeping position does affect initial postoperative knee terminal extension; however, there is no effect on patient reported outcomes. We found a statistically significant difference in extension when comparing patients in the supine versus lateral group. Patients who slept in the lateral position lacked 6.03 degrees of extension which is greater than the 5 degrees threshold needed for normal gait mechanics. Conversely, those in the supine group only lacked 2.98 degrees of extension, allowing for normal gait mechanics. This study identifies an easy, effective means of increasing patient knee range of motion following TKA.
Predictors of thyroid cancer survival in Saudi Arabia: A retrospective 10-year analysis
Authors: Bawazir Amen , Alhalafi Sadeem , Al-Aidaross Omer , Jazieh Abdulrahman , Khan Wasif Ali 
Published: September 2024

Background: Thyroid cancer (TC) is becoming more prevalent in Saudi Arabia, currently ranking among the top three cancers affecting women. Despite its rising prevalence, there has been limited assessment of the factors influencing the survival rate (SR) among the Saudi population over an extended period. Therefore, this study aims to address this critical gap in knowledge by identifying the factors affecting the SR of TC, comparing the SR with previous studies, and exploring potential areas for improving the SR of patients.
Methods: A retrospective study analyzed secondary data from patients diagnosed with TC, as recorded in the King Abdulaziz Medical City Cancer Registry in Riyadh, Saudi Arabia, over 10 years from 2009 to 2018.
Results: Of the total 665 TC cases, the mean age at diagnosis was 46.2 years (±SD 16), and most patients were women (78.5%), with the majority being under 50 years old. The most common type of cancer was papillary thyroid carcinoma, comprising 88.6% of all TCs. Over half of the cases were localized to one of the lobes of the thyroid gland, with almost equal frequency between the two lobes. The 5-year SR of localized papillary thyroid carcinoma reached 96.5%, in contrast to the extremely low SR of anaplastic thyroid carcinoma, where most patients died within a few months of the diagnosis. Factors such as morphology, tumor extension, male gender, and age at diagnosis significantly impacted patient survival, as analyzed by the Kaplan–Meier test (p < 0.001). Compared to other types of cancer, those with anaplastic thyroid carcinoma had a lower SR.
Conclusion: The SR of TC patients is predicted by factors such as their age, morphological type, and the presence of distant metastasis.
Liver ultrasound evaluation of acutely increased liver function tests of COVID-19 hospitalized patients
Authors: Almughalles Salah , Khojaly Shazaly N. , Nashwan Abdulqadir J. , Darweesh Adham 
Published: September 2024

Background: The incidence of hepatic abnormalities has been notably higher following the coronavirus disease 2019 (COVID-19) infection, attributed to the virus’s entry into cells via angiotensin-converting enzyme 2 (ACE2) surface expression. The gastrointestinal tract’s significant ACE2 expression, alongside a lesser degree in the biliary epithelium, has been implicated in gastrointestinal symptoms and liver injury.
Purpose: The aim of this study was to determine whether specific ultrasonographic findings in the liver correlate with acute increases in liver function tests (LFTs) among hospitalized patients.
Methods: A retrospective analysis was conducted on hospitalized COVID-19 patients at Hazem Mebaireek General Hospital in Qatar, from March 1, 2020, to June 30, 2020. The study focused on patients who experienced acute increases in LFTs, excluding those with chronic liver disease. Ultrasound imaging and patient records were reviewed to gather data.
Results: Out of 223 ultrasound studies of COVID-19 patients, 158 met the inclusion criteria. The majority were male, with a mean age of 47.76 ± 13.76 years. Ultrasound results showed 43.7% normal liver parenchyma, while 56.3% exhibited nonspecific abnormalities such as diffuse liver hyperechogenicity (39.2%), enlargement with diffuse hyperechogenicity (12.7%), and other findings (4.4%). The biliary tree was predominantly normal (96.2%), with 3.8% showing abnormalities, including intrahepatic (2.5%) and extrahepatic (1.3%) dilatation. Gallbladder evaluations were normal in 60.1% of cases, with 39.9% showing abnormalities like stones (6.3%), stones with sludge (13.3%), polyps (6.3%), wall thickening (1.9%), and other conditions (12%). A significant correlation was found between abnormal liver parenchyma findings and elevated levels of bilirubin (total and direct) and alkaline phosphatase, with p-values < 0.05. Only aspartate aminotransferase levels showed a significant correlation with biliary tree abnormalities.
Conclusion: The most common ultrasonographic finding associated with acute increases in LFTs among hospitalized COVID-19 patients was diffuse liver hyperechogenicity, with or without enlargement. These findings suggest a nonspecific yet significant association with liver function anomalies in the context of COVID-19.
DAANISH: A mnemonic to aid in memorizing and recalling important strategies contributing to the prevention of perioperative stroke
Authors: Mitarnun Witoon 
Published: September 2024

Background: Perioperative stroke, defined as a stroke occurring within 30 days post-surgery, typically emerges within the first week. The incidence of perioperative stroke among adults undergoing non-cardiac and non-neurological surgeries ranges from 0.1% to 1% after a surgical intervention. Mortality rates following perioperative stroke surge, reaching up to eight times higher than controls, with approximately one in four cases resulting in death. Fortunately, various strategies are available to potentially prevent perioperative strokes. However, the vast amount of data poses challenges for physicians in memorization and recall for clinical use. This study aims to summarize essential perioperative stroke prevention strategies and determine an effective mnemonic for their memorization and recall.
Method: The initial search in PubMed focused solely on review articles published within the last 10 years. It utilized the keywords “perioperative stroke” and “prevention.”
Results: An initial search found 39 articles, with two suitable for review. Using data from selected review articles, further searches were conducted on Google Scholar and PubMed for articles from 2000 to 2024, identifying 30 additional suitable references. From these 32 articles, the author developed a mnemonic, “DAANISH,” to aid in remembering strategies for preventing perioperative stroke.
Conclusion: Implementing this mnemonic may help reduce the risk of perioperative stroke and improve patient outcomes. Future research is needed to confirm its effectiveness.
Pengolahan Air Limbah Wudhu Menjadi Air Siap Pakai Non Konsumtif di Lingkungan Pondok Pesantren Darul Aman Gombara
Authors: Irmawanty Irmawanty , Hayati Riza Sativani , Syam Haerul 
Published: September 2024

Air merupakan salah satu kebutuhan esensial bagi makhluk hidup. Air yang dibutuhkan ini tentunya air bersih yang dapat digunakan untuk berbagai aktifitas sehari-hari. Melihat banyaknya penggunaan air maka perlu dilakukan pengolahan limbah air agar tidak terbuang percuma ke badan air. Salah satu limbah air yang dapat diolah kembali adalah air limbah wudhu. Dalam lingkungan Pesantren, volume air wudhu jumlahnya sangat tinggi setiap harinya. Untuk itu maka perlu dilakukan re-use atau pengolahan agar dapat digunakan kembali. Pengolahan air limbah wudhu dilakukan dengan metode filtrasi agar diperoleh air yang siap pakai. Metode filtrasi yang dilakukan adalah secara biologi, fisika dan kimiawi. Hasil akhir dari pengolahan ini menghasilkan air yang dapat digunakan untuk peruntukan kolam ikan. Kegiatan ini memberi banyak manfaat di antaranya pemanfaatkan air limbah wudhu, menambah kegiatan ekstrakurikuler santri yaitu budidaya ikan dengan air yang telah tertampung dalam kolam ikan yang telah dibuat.
Deformation in the Carbonate Rocks of the Lennard Shelf
Authors: Dörling S.L. , Dentith M.C. , Playford P.E. 
Published: September 2024

Abstract
Faulting is an important control during carbonate reef development and evolution, and is widely documented (e.g. Burchette, 1988; Crevello et al., 1 989: Tucker et al., 1990). Generally, the tectonic style during reef growth is characterized by phases of extension, rifting and subsidence associated with marine transgression. These tectonic processes exert a controlling role on reef development, in that they determine the spatial and geometric distribution of reefs, and reef-bounded platforms. Elongated reefal build-ups form parallel to subsiding passive cratonal margins (Wilson, 1990), or platforms develop over and around fault blocks along such borders (e.g. Burchette, 1988; Ellis et al., 1990). Narrow platform rims with a spectrum of carbonate facies, such as the Devonian reefs of the Lennard Shelf (Playford et al., 1989), may evolve fringing a major subsiding basin in which there are fault controls on reef distribution.
Discussion
Authors: Vearncombe J.R. , Chisnall A.W. , Christensen J.N. , Dentith M.C. , Dörling S.L. , Reed A.R. 
Published: September 2024

Abstract
The movement of MVT-forming brines has been tied to the histories of adjacent sedimentary basins, but the precise causal link is still not well established because the timing of MVT mineralization is usually poorly constrained relative to basin evolution (see Chapter 1). Thus, the precise dating of MVT mineralization would allow discrimination among the various models for the transport of the fluids responsible for ore deposition.
Geological relationships which may give a time constraint on mineralization are often ambiguous. Until the successful development of Rb-Sr dating of sphalerite (Nakai et al., 1993), some deposits, such as Pine Point (Canada), were constrained only by the age of the host rocks representing the maximum age of the deposit, and a knowledge of when it was first found by man (see Garven and Sverjensky, 1 994; Lyons, 1994). On the Lennard Shelf we can be more precise because the deposits are hosted in Devonian limestones, and Zn-Pb mineralization in faults and veins is truncated by the unconformity at the base of the late Carboniferous and Permian Grant Group. Locally, as at Blendevale, detrital clasts of mineralized limestone are preserved in erosional channels filled with Grant Group sandstone, thus providing a minimum age for mineralization as late Carboniferous. However, as with MVT deposits worldwide, the precise date on mineralization is controversial.