bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study the effect of adding rectangular fins along the riser pipe on the thermal performance of the flat‐plate solar water heater system
Authors: Theeyzen Sabaa , Freegah Basim 
Published: October 2024

AbstractThe earlier studies investigated many parameters affecting the flat plate solar collectors (FPSCs) while employing an active approach to transmit the heat transfer fluid and running under a constant heat flux. In contrast, the presented study investigates enhancing the thermal performance through added fins with different heights and numbers to FPSC in a changing heat‐flux condition and relies on a passive technique. Thus, Models A, B, and C included adding five fins along the riser‐pipe with heights of 5, 7.5, and 10 mm, respectively, while Models D and E used four and three fins of 10 mm height, and the numerical calculations were conducted using ANSYS Fluent 2022R1. Then, the experimental work was done for the traditional model in Baghdad City, Iraq, to validate the results of numerical work, and the numerical and experimental work difference was found to be 10.17% for the tank's average temperature and the heat transfer liquid's temperature at the riser outlet is 10.14%. The numerical results indicate that the thermal efficiency of the system in all test models (A, B, C, D, and E) is enhanced than the classical model regarding the water's temperature in the tank and the working liquid's temperature at the pipe's outlet. In addition, the study concluded that Model C achieved a greater overall thermal efficiency than the traditional model by 38.59% and higher than Models A, B, D, and E by 11.77%, 6.65%, 8.19%, and 18.09%, respectively.
Association between family history with lung cancer incidence and mortality risk in the Asia Cohort Consortium
Authors: Kishida Rie , Yin Xin , Abe Sarah Krull , Rahman Md. Shafiur , Saito Eiko , Islam Md. Rashedul , Lan Qing , Blechter Batel , Rothman Nathaniel , Sawada Norie , Tamakoshi Akiko , Shu Xiao‐Ou , Hozawa Atsushi , Kanemura Seiki , Kim Jeongseon , Sugawara Yumi , Park Sue K. , Kweon Sun‐Seog , Ahsan Habibul , Boffetta Paolo , Chia Kee Seng , Matsuo Keitaro , Qiao You‐Lin , Zheng Wei , Inoue Manami , Kang Daehee , Seow Wei Jie 
Published: October 2024

AbstractFamily history of lung cancer (FHLC) has been widely studied but most prospective cohort studies have primarily been conducted in non‐Asian countries. We assessed the association between FHLC with risk of lung cancer (LC) incidence and mortality in a population of East Asian individuals. A total of 478,354 participants from 11 population‐based cohorts in the Asia Cohort Consortium were included. A Cox proportional hazards regression model was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). A total of 7,785 LC incident cases were identified. FHLC (any LC subtype) was associated with an increased risk of LC incidence (HR = 1.45, 95% CI = 1.30–1.63). The positive association was observed in men and women (HR = 1.44, 95% CI = 1.26–1.66 in men; HR = 1.47, 95% CI = 1.22–1.79 in women), and in both never‐smokers and ever‐smokers (HR = 1.43, 95% CI = 1.18–1.73 in never‐smokers; HR = 1.46, 95% CI =1.27–1.67 in ever‐smokers). FHLC was associated with an increased risk of lung adenocarcinoma (HR = 1.63, 95% CI: 1.36–1. 94), squamous cell carcinoma (HR = 1.88, 95% CI: 1.46–2.44), and other non‐small cell LC (HR = 1.94, 95% CI: 1.02–3.68). However, we found no evidence of significant effect modification by sex, smoking status, and ethnic groups. In conclusion, FHLC was associated with increased risk of LC incidence and mortality, and the associations remained consistent regardless of sex, smoking status and ethnic groups among the East Asian population.
Exploring the cessation process from adolescence to young adulthood in individuals with lived experience of nonsuicidal self‐injury: a qualitative study
Authors: Andersson H. , Korhonen L. , Holmqvist Larsson K. , Gustafsson B. M. , Zetterqvist M. 
Published: October 2024

AbstractIntroductionNonsuicidal self‐injury (NSSI) is a common and concerning behavior in adolescents. However, most adolescents cease NSSI as they transition into adulthood. Increased knowledge of the cessation process is needed. This study aimed to qualitatively explore the factors contributing to NSSI cessation in individuals with lived experience of NSSI, providing valuable insights for treatment strategies.MethodsTwenty‐six individuals assigned female sex at birth, between ages 20–22 years, from Sweden were interviewed between 2021 and 2023 in Linköping, Sweden. Of these, 21 individuals perceived themselves as having ceased NSSI and were included in the analysis. Thematic analysis and Hooley and Franklins' Benefits and Barriers Model of NSSI were used to analyze the transcripts.ResultsThree overarching themes were generated: “Something inside me changed”, “Something in my close relationships changed”, and “Something in my life context changed”. The cessation of NSSI was associated with several key factors. Improved well‐being and envisioning a different future were pivotal in initiating the cessation process. Additionally, interpersonal relationships and support from others were interpreted as powerful motivators for change. Transitioning to a new social context and leaving behind a destructive environment provided opportunities for personal growth and enhanced well‐being, interpreted as initiators in the participants' broader life context.ConclusionThis study underscores the complexity of the NSSI cessation process and highlights the need for a comprehensive understanding of the underlying factors. Access to emotion regulation skills was perceived as a significant barrier to NSSI engagement. Clinical implications and different interventions to support NSSI cessation are discussed.
Developmental trajectories of students' beliefs about social success: Differences between students with and without a middle school transition
Authors: Brass Nicole R. , Ryan Allison M. 
Published: October 2024

AbstractIntroductionAttaining social success is a significant concern during early adolescence. The characteristics that youth believe will bring social success are known to change over time and vary across contexts, especially over the transition to middle school.MethodsThe analytic sample included 614 students (52% girls, 48% boys; 53% Black, 47% White) from the Midwestern United States. At yearly intervals during grades 6–8, participants completed self‐report surveys assessing their endorsement of five characteristics (sincerity, academic responsibility, dominance, disingenuity, athleticism/attractiveness) that described peers in their grade who have lots of friends and get along well with others (i.e., social success). The sample included students who attended the same school from kindergarten‐eighth grade (K8) and students who made a transition from an elementary to a middle school after 6th grade (ESMS).ResultsMultigroup longitudinal growth models revealed some concerning trends over time. For both ESMS and K8 students, their endorsement of sincerity decreased, their endorsement of disingenuity increased, and their endorsement of athleticism/attractiveness was high and stable. ESMS students' endorsement of academic responsibility decreased over time and their endorsement of dominance showed increasing trends. K8 students' endorsements of academic responsibility and dominance were stable. However, across contexts, compared to the other characteristics, sincerity was most often ranked the highest.ConclusionsThe findings highlight that some changes in students' beliefs about social success may be unique to students who experience a school transition whereas others may be developmentally normative. Implications for the education of young adolescent students are discussed.
KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53‐Mediated Tumor Suppressor Pathway
Authors: Hasan Arif Ul , Serada Satoshi , Sato Sachiko , Obara Mami , Hirata Sho , Nagase Yukako , Kondo Yukiko , Taira Eiichi 
Published: October 2024

ABSTRACTDespite significant advances in the treatment of cutaneous melanoma (hereafter melanoma), the prognosis remains less favorable due to therapeutic resistance, which is presumably linked to epigenetic dysregulation. We hypothesized that the histone lysine demethylase KDM4B could play a pivotal role in controlling therapy‐resistant melanoma. To validate our hypothesis, we retrieved RNA sequencing data from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) program and observed upregulation of KDM4B in both primary and metastatic melanoma, which was associated with poor survival. To explore its role, we used murine B16, human SK‐MEL‐5, and G‐361 melanoma cells as in vitro models of melanoma. We found that KDM4B inhibition using NCGC00244536 increased global levels of H3K9me3 and downregulated the expressions of cell cycle progression–related genes Cdk1, Cdk4, Ccnb1, and Ccnd1. Moreover, genetic ablation of KDM4B or its chemical inhibition using NCGC00244536 reduced p53 production by upregulating MDM2, which enhances the proteolytic degradation of p53. Interestingly, despite the reduction of p53, these interventions augmented apoptosis and senescence‐induced cell death by activating pathways downstream of p53, as evidenced by reduced levels of pro‐survival Bcl‐2 and Bcl‐xL proteins and increased production of pro‐apoptotic cleaved caspase‐3, caspase‐7, Bax, and the senescence inducer Cdkn1a. Compared to the FDA‐approved anti‐melanoma agent dacarbazine, NCGC00244536 exhibited more pronounced cytotoxic and antiproliferative effects in melanoma cells. Importantly, NCGC00244536 demonstrated minimal cytotoxicity to low Kdm4b‐expressing mouse embryonic fibroblasts. In conclusion, our findings suggest that KDM4B inhibition can override the antitumor effect of p53, and potentially serve as a therapeutic strategy for melanoma.
Undergraduate endodontic curricula across Canadian Dental Schools: A cross‐sectional analysis
Authors: Goyal Dee , Alghahtani Fahda , Santos Juliana Nascimento , Graziotin Renata , Hieawy Ahmed 
Published: October 2024

AbstractIntroductionThis study aimed to evaluate and assess the degree of uniformity in endodontics education at the undergraduate level among Canadian dental schools. The objective is to enhance Canadian dental education programs to meet societal oral health needs while incorporating advancements in the field of endodontics.MethodsAn online survey comprising 36 multiple‐choice questions targeting the nature of endodontic teaching was conducted as our methodology. Participation was sought from directors of the undergraduate endodontics program at all ten Canadian dental schools in 2021 and 2022.ResultsA remarkable 100% response rate and the findings revealed a certain level of consistency among Canadian schools concerning pedagogical and assessment methods, as well as the endodontic topics taught to undergraduate students. However, notable variations were observed in the equipment and materials utilized. This study serves as a fundamental reference for identifying future modifications to the undergraduate endodontics curriculum in Canada.
Incidence and risk factors of de novo hepatitis E virus infection after receiving liver transplantation
Authors: He Ping , Li Jialei , Wang Chen , Zhang Jiayue , Jiang Yiyun , Liu Hongyang , Zhao Yao , Li Zhiwei , Gao Yinjie , Wang Yijin 
Published: October 2024

AbstractOrgan transplant recipients with hepatitis E virus (HEV) infection bears high risk to develop chronic hepatitis, which is generally associated with immunosuppressive therapies. This study aimed to identify the incidence and predictors of de novo HEV infection in patients after receiving transplantation. We performed a large retrospective study to investigate the prevalence of anti‐HEV at baseline, incidence of de novo HEV infection after transplantation, and the risk factors of HEV infection among patients with liver transplant in China. A total of 407 liver transplant recipients were examined for the presence of anti‐HEV immunoglobulin G, IgM antibodies, and HEV RNA in serum. Basal indexes in individuals with evidence of post‐transplant HEV infection were compared with those without evidence of that, and risk factors associated with HEV infection were assessed. The prevalence of anti‐HEV at pretransplant in liver transplant recipients was 25.8% (105/407). Serum‐negative conversion occurred in 34 (32.38%) of 105 liver transplant patients. Sixty‐five out of 302 patients had de novo HEV infection after transplantation, with a cumulative incidence of 42.74% during follow‐up. After transplantation, HEV infection was associated with liver failure (p = 0.012), hypoproteinemia (p = 0.030) and higher level of r‐glutamyl transferase (GGT) (p = 0.022) before transplantation. Graft rejection (OR = 0.075; p = 0.045) was negatively associated with serum‐negative conversion in patients who had positive anti‐HEV antibody before transplantation. The incidence of de novo HEV infection after transplantation were higher in China. Liver failure, hypoproteinemia, and GGT elevation may be associated with HEV infection after liver transplantation. This study suggests that prevention and control of HEV infection after liver transplantation should be paid attention in patients bearing these risk factors.
Influenza outbreak during the surge of SARS‐CoV‐2 omicron in a metropolitan area from southern Brazil: genomic surveillance
Authors: de Abreu Góes Pereira Vyctoria Malayhka , Gularte Juliana Schons , Demoliner Meriane , da Silva Mariana Soares , Girardi Viviane , Filippi Micheli , Frohlich Julia , Fink Pietra , Hansen Alana Witt , Ferreira Helena Lage , Afrough Babak , Kritz‐Wilson Angelika , Spilki Fernando Rosado 
Published: October 2024

AbstractInfluenza circulation was significantly affected in 2020–21 by the COVID‐19 pandemic. During this time, few influenza cases were recorded. However, in the summer of 2021–22, an increase in atypical influenza cases was observed, leading to the resurgence of influenza in the southernmost state of Brazil, Rio Grande do Sul (RS). The present study aimed to identify the circulation of FLUAV, FLUBV and SARS‐CoV‐2 and characterize the influenza genomes in respiratory samples using high‐throughput sequencing technology (HTS). Respiratory samples (n = 694) from patients in RS were selected between July 2021 and August 2022. The samples were typed using reverse transcriptase real‐time PCR (RT‐qPCR) and showed 32% (223/694) of the samples to be positive for SARS‐CoV‐2, 7% for FLUAV (H3) (49/694). FLUBV was not detected. RT‐qPCR data also resulted in FLUAV and SARS‐CoV‐2 co‐infections in 1.7% (4/223) of samples tested. Whole genome sequencing of FLUAV produced 15 complete genomes of the H3N2 subtype, phylogenetically classified in the 3C.2a1b.2a.2a.3 subclade and revealing the dominance of viruses in the southern region of Brazil. Mutation analysis identified 72 amino acid substitutions in all genes, highlighting ongoing genetic evolution with potential implications for vaccine effectiveness, viral fitness, and pathogenicity. This study underscores limitations in current surveillance systems, advocating for comprehensive data inclusion to enhance understanding of influenza epidemiology in southern Brazil. These findings contribute valuable insights to inform more effective public health responses and underscore the critical need for continuous genomic surveillance.
Climate variability in West Anatolia from Last Glacial Maximum to present based on the µXRF data from Buldan Yayla Lake (Denizli)
Authors: DoĞan Mustafa , Ünlü Yasemin , Gürboğa Şule , Fiołna Sabina , Şenkul Çetin 
Published: October 2024

ABSTRACTStudying climate changes in the Eastern Mediterranean and Aegean region, particularly in Western Anatolia, is crucial for understanding environmental dynamics over time. We present high‐resolution, long‐term micro‐X‐ray fluorescence data from Buldan Yayla Lake (Denizli‐Buldan), a key area, covering the period from the Last Glacial Maximum (LGM) to the present. Sedimentological and paleoclimate data are supported by high‐resolution radiocarbon analyses, as well as two tephra chronologies from Cape Riva and Minoan. According to the results, a cold and arid climate is observed during the LGM, Post‐LGM and Younger Dryas. From the LGM to the present, there has been a trend towards increasing warmth and humidity. During the Late Glacial (LG) and Holocene (especially in the early Holocene), the climate was warmer and more humid. A short‐lived climate change associated with the Older Dryas is recorded during the Bølling–Allerød warm period (~13 200–12 350 cal a bp) within the LG. The data indicate that the sediment cores of Buldan Yayla Lake are highly sensitive in reflecting climate information between the LGM and the present day. At the same time, the climate in Western Anatolia is recorded as more stable throughout the Holocene. In conclusion, this study enhances our understanding of Western Anatolia's climate dynamics and environment–society relationship from the LGM to the present.
A novel isolation technique for sweetpotato starch and its application in thermal property characterization
Authors: Zhao Lingxiao , Wang Jie , Xiao Shizuo , Du Mingjuan , Zhao Donglan , Dai Xibin , Zhou Zhilin , Cao Qinghe 
Published: October 2024

AbstractBACKGROUNDThe utilization of sweetpotato starch in the food industry is significantly influenced by the granule size of the starch. To isolate sweetpotato starch fractions with different sizes, an efficient isolation method is in demand. The differences in thermal properties of starch fractions with different sizes from various sweetpotato varieties were revealed insufficiently.RESULTSIn this study, we devised a time‐saving isolation technique to effectively isolate sweetpotato starch fractions based on granule sizes. The new technique was proved applicable for sweetpotato varieties with different flesh colors. The amylose contents of the isolated starch fractions were in the range 16.49–23.27%. A positive association was observed between amylose content, relative crystallinity of starch fractions and their granule size. Conversely, both the swelling power and water solubility at 95 °C displayed a consistent decline from more than 30 g g−1 to lower than 20 g g−1 as the granule size increased. Tp, To and Tc decreased gradually with an increase of starch granule size, while the medium‐ or small‐sized starch fractions showed higher ΔH. In the first stage of thermogravimetric analysis curves, the weight of the small‐sized starch fractions decreased the slowest, but no definite pattern was detected in the second or third stage.CONCLUSIONTherefore, the newly established technique and the results of this study will help better understand the properties of sweetpotato starch fractions with different sizes and certainly provide guidelines for the utilization of sweetpotato starch in food processing and product development. © 2024 Society of Chemical Industry.
Disparities in Health Outcomes in Surgical Oncology
Authors: Johnson Shaneeta M. , Miller‐Hammond Kimberly , McKenzie‐Johnson Tamra , Stewart John 
Published: October 2024

ABSTRACTCancer health disparities refer to the unequal burden, treatment, and outcomes of cancer care experienced by specific populations. These disparities are systemic and often preventable, impacting diverse populations, including racial and ethnic minorities, medically underserved populations, populations in rural areas, individuals from the LGBT communities, disabled persons, extremes of age, and those living in persistent poverty. Addressing this topic is essential and timely to ensure equitable oncologic outcomes for all populations. Experts in surgical oncology and health disparities have collaborated to produce this seminar issue on Disparities in Surgical Oncology.
Perceptions and tolerance of American crocodiles and their management by South Florida residents
Authors: Deem Vincent R. , Cleary Matteo , Steen David A. 
Published: October 2024

AbstractThe American crocodile (Crocodylus acutus) is a federally and state‐protected species classified as threatened by the United States Fish and Wildlife Service and the State of Florida; however, its population has increased since gaining legal protection in 1967. Concurrently, the number of reported human–crocodile conflicts has also increased, analogous to known conflicts surrounding other large (typically terrestrial) predators recovering from historical population declines. Although biology and ecology are the foundation of effective wildlife management strategies, human dimensions need to be considered to develop realistic and attainable conservation objectives. To better understand how South Florida residents perceive American crocodiles and their management, we used a mixed‐mode internet and mail survey. We obtained survey data from 28 May 2021 to 20 September 2021 from people living within the range of the American crocodile in Florida. There was little variation in opinions of 6 management actions presented for consideration under each of 3 different human–crocodile interaction scenarios. The strongest consensus was around euthanizing a crocodile (highly unacceptable under all 3 scenarios) with the management action of leaving the crocodile alone and monitoring the situation showing the least amount of consensus and shifting from slightly acceptable to slightly unacceptable the closer a hypothetical crocodile was in proximity to a resident's private property. Regression modeling showed respondents who were older, female, and those with children at home were less likely to prefer an increase in the crocodile population. Respondents who perceived more benefits from crocodiles and less risk from them tended to be relatively knowledgeable about crocodiles, had higher trust in the Florida Fish and Wildlife Conservation Commission (FWC), and were more likely to prefer a larger crocodile population. Further, spatial mapping revealed variation in tolerance for crocodiles and trust in FWC's ability to manage them. We reveal opportunities for targeted education and outreach efforts with the potential to affect tolerance of a large reptilian carnivore in a region experiencing rapid human development.
More knee reinjuries after ACL reconstruction compared to nonsurgical treatment of the ACL. A 2‐year follow‐up of the NACOX prospective cohort study
Authors: Selin Anna S. , Gauffin Håkan , Hedevik Henrik , Fältström Anne , Kvist Joanna 
Published: October 2024

AbstractPurposeTo describe knee reinjuries and surgeries within 2 years after an acute anterior cruciate ligament (ACL) injury, in patients treated with or without ACL reconstruction (ACLR).MethodsTwo years follow‐up of 275 patients (52% females, mean age 25.2 [SD 7.0] years) about knee reinjuries and surgeries were analysed from the prospective NACOX cohort study, aiming to describe recovery after an acute ACL injury treated according to clinical routine. Knee reinjury was defined as increase or new symptoms due to new trauma. At 2 years after injury, 169 (61%) had undergone an ACLR. Results are presented with descriptive statistics and risk ratios (RR).ResultsThirty‐two patients sustained reinjuries within 2 years; 6 in the non‐ACLR group, and 26 in the ACLR group (7 before and 19 after ACLR). Twelve patients in the ACLR group sustained a graft rupture and three did an ACL revision. Patients with non‐ACLR, aged 21–25 years, had a 5.9‐fold higher risk for reinjury than those aged 15–20 years (RR 5.9 [1.3–26.9]; p = 0.012). Twenty‐four patients had surgery in the non‐ACLR group and 36 patients in the ACLR group (excluding primary ACLR), where six were before ACLR and 30 were after ACLR.ConclusionTwelve percent sustained a knee reinjury and 21% underwent knee surgery within 2 years after the index ACL injury. There was a higher reinjury incidence in the ACLR group, but no difference in incidence of surgeries. Thus, ACLR did not reduce the risk of traumatic reinjuries or surgeries, which is important for treatment decision considerations.Level of EvidenceLevel I.