bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dietary Intake of DHA and EPA in a Group of Pregnant Women in the Moncton Area
Authors: Bishop Nicole Arsenault , Leblanc Caroline P. 
Published: February 2017

Purpose: To compare docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and fish intake of pregnant women at 30 weeks of gestation to current recommendations and to determine the factors associated with omega-3 (ω-3) intake. Methods: A food frequency questionnaire was completed by 54 women (54/131 = 41%) at 30 ± 0.8 weeks gestation. Supplement intake, sociodemographic characteristics, and ω-3 food habits were evaluated. Results: Among this high socioeconomic status (SES) group, 66.7% and 64.8% met the Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) recommendation of 200 mg/d DHA and 300 mg/d DHA + EPA, respectively, and only 48.1% met the Academy of Nutrition and Dietetics (Academy) recommendation of 500 mg/d DHA + EPA. Eighteen of the 54 women took a ω-3 supplement during the third trimester. This significantly improved their total intake to meet the FAO/WHO (88.9% ≥200 mg/d DHA and 94.4% ≥300 mg/d DHA + EPA) and the Academy (77.8% ≥500 mg/d DHA + EPA) recommendations. Among nonsupplement users (36/54), 50% met the FAO/WHO recommendations and only 33.3% met the Academy recommendations. Conclusions: Results suggest that the majority of high SES women did not meet ω-3 recommendations from food alone. Continued prenatal education on the importance of fish intake and on the addition of ω-3 prenatal supplement is essential.
The Voice of Experience: Diet and Weight Change in Women with Breast Cancer Associate with Psychosocial and Treatment-Related Challenges
Authors: Vance Vivienne , Campbell Sharon , Mccargar Linda , Mourtzakis Marina , Hanning Rhona 
Published: February 2017

Purpose: This study investigated relationships between psychosocial and treatment-related factors, diet, and weight change in women treated with chemotherapy for early-stage breast cancer. Methods: Comprehensive qualitative interviews were conducted with 28 women who were within 12 months of completing chemotherapy treatment. Results: Changes in food intake and eating patterns were universal over the course of chemotherapy, with broad variability in treatment effects and associated dietary responses linked to weight change. Increased appetite, food cravings, and intake of energy-dense comfort foods were more common among women who gained weight during treatment (n = 11). Changes in taste, nausea, and emotional distress were central in promoting these dietary responses. Women who lost weight during treatment (n = 6) tended to report more severe and persistent side effects of treatment leading to poor appetite and lower food intake, and they were more likely to live alone. Conclusions: While the etiology of weight change in this population is complex, this study suggests that changes in food intake related to treatment and psychosocial challenges may play an important role for some women. These findings may help to identify women who are most at risk of weight change during treatment and may inform the development of tailored dietary interventions.
Multilevel cervical arthroplasty: current evidence. A systematic review
Authors: Joaquim Andrei F. , Riew K. Daniel 
Published: February 2017

OBJECTIVE
Cervical disc arthroplasty (CDA) has been demonstrated to be an effective treatment modality for single-level cervical radiculopathy or myelopathy. Its advantages over an anterior cervical discectomy and fusion (ACDF) include motion preservation and decreased reoperations at the index and adjacent segments up to 7 years postoperatively. Considering the fact that many patients have multilevel cervical disc degeneration (CDD), the authors performed a systematic review of the clinical studies evaluating patients who underwent multilevel CDA (2 or more levels).

METHODS
A systematic review in the MEDLINE database was performed. Clinical studies including patients who had multilevel CDA were selected and included. Case reports and literature reviews were excluded. Articles were then grouped according to their main study objective: 1) studies comparing multilevel CDA versus ACDF; 2) studies comparing single-level CDA versus multilevel CDA; and 3) multilevel CDA after a previous cervical spine surgery.

RESULTS
Fourteen articles met all inclusion criteria. The general conclusions were that multilevel CDA was at least as safe and effective as ACDF, with preservation of cervical motion when compared with ACDF and potentially with fewer reoperations expected in most of the studies. Multilevel CDAs are clinically effective as single-level surgeries, with good clinical and radiological outcomes. Some studies reported a higher incidence of heterotopic ossification in multilevel CDA when compared with single-level procedures, but without clinical relevance during the follow-up period. A CDA may be indicated even after a previous cervical surgery in selected cases.

CONCLUSIONS
The current literature supports the use of multilevel CDA. Caution is necessary regarding the more restrictive indications for CDA when compared with ACDF. Further prospective, controlled, multicenter, and randomized studies not sponsored by the device manufactures are desirable to prove the superiority of CDA surgery over ACDF as the treatment of choice for CDD in selected cases.
Current practice of cervical disc arthroplasty: a survey among 383 AOSpine International members
Authors: Chin-See-Chong Timothy C. , Gadjradj Pravesh S. , Boelen Robert J. , Harhangi Biswadjiet S. 
Published: February 2017

OBJECTIVE
The use of cervical disc arthroplasty (CDA) in spinal practice is controversial. This may be explained by the lack of studies with a large sample size and long-term outcomes. With this survey the authors aimed to evaluate the opinions of spine surgeons on the use of CDA in the current treatment of cervical disc herniation (CDH).

METHODS
A web-based survey was sent to all members of AOSpine International by email using SurveyMonkey on July 18, 2016. A single reminder was sent on August 18, 2016. Questions included geographic location; specialty; associated practice model; number of discectomies performed annually; the use of CDA, anterior cervical discectomy (ACD), and anterior cervical discectomy and fusion (ACDF); and the expectations for clinical outcomes of these procedures.

RESULTS
A total of 383 questionnaires were analyzed. Almost all practitioners (97.9%) were male, with a mean of 15.0 ± 9.7 years of clinical experience. The majority of responders were orthopedic surgeons (54.6%). 84.3% performed ACDF as the standard technique for CDH. 47.8% of the surgeons occasionally used CDA, whereas 7.3% used CDA as standard approach for CDH. The most common arthroplasty device used was the ProDisc-C. Low evidence for benefits and higher costs were the most important reasons for not offering CDA. The risk of adjacent-level disease was considered smaller for CDA as compared with ACDF. However, ACDF was expected to have the highest effectiveness on arm pain (87.5%), followed by CDA (77.9%), while ACD had the least (12.6%).

CONCLUSIONS
In this survey, CDA was not considered to be the routine procedure to treat CDH. Reported benefits included the reduced risk of adjacent-level disease and preservation of motion of the neck. Lack of enough evidence on its effectiveness as well as higher costs were considered to be disadvantages of CDA. More research should be conducted on the implementation impact of CDA and the cost-effectiveness from society's perspective.
<i>In vitro</i> Regeneration and Rapid Multiplication of <i>Dendrobium bensoniae</i>, an Indigenous Ornamental Orchid
Authors: Riva S S , Islam A , Hoque M E 
Published: February 2017

An experiment was conducted on in vitro regeneration and multiplication of Dendrobium bensoniae. Different concentrations of BA and IBA alone or combination of both hormones were used as treatment for regeneration. It was revealed that shoot regeneration from node was the best at 2.0 mg/l BA supplemented to MS medium. It gave better responses than all other concentrations and combinations of BA and BA+IBA, used in the present study. The highest number of shoots and leaves were found when 1.0 mg/l BA with 1.5 mg/l IBA was supplemented into MS medium. For rooting, 0.5 mg/l BA with 1.0 mg/l IBA was found to be the most effective. The well-rooted plantlets were successfully acclimatized under 70-80% humidity and planted in pots and transferred to the shade house for establishment. Around 85% of plantlets survived in the field. From the present result, it may be recommended that MS medium supplemented with 2.0 mg/l BA may be used for rapid shoot induction and regeneration of D. bensoniae.The Agriculturists 2016; 14(2) 24-31
The First Simultaneous X-Ray/Radio Detection of the First Be/BH System MWC 656
Authors: Ribó M. , Munar-Adrover P. , Paredes J. M. , Marcote B. , Iwasawa K. , Moldón J. , Casares J. , Migliari S. , Paredes-Fortuny X. 
Published: February 2017

Abstract
MWC 656 is the first known Be/black hole (BH) binary system. Be/BH binaries are important in the context of binary system evolution and sources of detectable gravitational waves because they are possible precursors of coalescing neutron star/BH binaries. X-ray observations conducted in 2013 revealed that MWC 656 is a quiescent high-mass X-ray binary (HMXB), opening the possibility to explore X-ray/radio correlations and the accretion/ejection coupling down to low luminosities for BH HMXBs. Here we report on a deep joint Chandra/VLA observation of MWC 656 (and contemporaneous optical data) conducted in 2015 July that has allowed us to unambiguously identify the X-ray counterpart of the source. The X-ray spectrum can be fitted with a power law with Γ ∼ 2, providing a flux of ≃4 × 10−15 erg cm−2 s−1 in the 0.5–8 keV energy range and a luminosity of L
X ≃ 3 × 1030 erg s−1 at a 2.6 kpc distance. For a 5 M⊙ BH this translates into ≃5 × 10−9 L
Edd. These results imply that MWC 656 is about 7 times fainter in X-rays than it was two years before and reaches the faintest X-ray luminosities ever detected in stellar-mass BHs. The radio data provide a detection with a peak flux density of 3.5 ± 1.1 μJy beam−1. The obtained X-ray/radio luminosities for this quiescent BH HMXB are fully compatible with those of the X-ray/radio correlations derived from quiescent BH low-mass X-ray binaries. These results show that the accretion/ejection coupling in stellar-mass BHs is independent of the nature of the donor star.
Postoperative Patient-Controlled Analgesia in the Pediatric Cardiac Intensive Care Unit
Authors: Epstein Hanna M. 
Published: February 2017

BACKGROUNDHigh rates of uncontrolled pain in critically ill patients remain common. Patient-controlled analgesia is more effective than traditional intravenous as-needed dosing regimens for managing postoperative pain in older children and adults.OBJECTIVETo determine whether pain-related clinical outcomes in patients from age 10 years to adult following cardiac surgery are improved by using patient-controlled analgesia as a pain management strategy.METHODSUsing the plan-do-study-act method of quality improvement, a process was instituted to have both staff and patients’ families support the use of patient-controlled analgesia postoperatively as opposed to traditional pain control with as-needed analgesics. Use of as-needed medications and pain scores were retrospectively compared from before to after initiation of patient-controlled analgesia.RESULTSThe cumulative mean pain score from the time of extubation through the following 24 hours decreased from 4.14 (on a scale from 0 to 10) when strictly as-needed medications were used to 2.8 with patient-controlled analgesia. Further, the mean amount of opioid consumed decreased from 14.98 mg of morphine and 22.27 mg of oxycodone to 13.58 mg of morphine and 3.33 mg of oxycodone after implementation of patient-controlled analgesia.CONCLUSIONSStandardized use of patient-controlled analgesia for postoperative pain management in patients 10 years of age through adulthood is efficient and effective, as evidenced by less medication being consumed by patients and lower mean pain scores.
Disertaciones elementales sobre teoría combinatoria: hacia una inculturación de las matemáticas
Authors: Reyes Centeno Marcos Antonio 
Published: February 2017

En este trabajo se abordó la enseñanza de la teoría combinatoria con dos tipos de problemas, aquellos cuyos resultados pueden ser comprobados por conteo directo y los que no pueden verificarse, porque la cantidad de eventos obtenidos no permiten por cuestiones de tiempo, verificar uno a uno, todos los arreglos obtenidos. Además, se determinó la utilidad didáctica y académica de ambos tipos de problemas. Otro aspecto que se incluyó es la atención a las singularidades, como parte de la atención a la diversidad: La atención particularizada que ha de darse a los estudiantes de avanzada.Se incorporó en este trabajo, una serie de ejemplos sobre problemas conmensurables y su uso didáctico, que no pretenden, por la brevedad del documento, dar una respuesta definitiva sobre la enseñanza de las técnicas de conteo, si no mostrar levemente, los posibles derroteros para abordar didácticamente esta apasionante temática. Se visualizaron también ejemplos de problemas inconmensurables y su utilidad académica, para atender las singularidades de estudiantes amantes de las matemáticas.
Profiling of microRNAs in tumor interstitial fluid of breast tumors – a novel resource to identify biomarkers for prognostic classification and detection of cancer
Authors: Halvorsen Ann Rita , Helland Åslaug , Gromov Pavel , Wielenga Vera Timmermans , Talman Maj‐Lis Møller , Brunner Nils , Sandhu Vandana , Børresen‐Dale Anne‐Lise , Gromova Irina , Haakensen Vilde D. 
Published: February 2017

It has been hypothesized based on accumulated data that a class of small noncoding RNAs, termed microRNAs, are key factors in intercellular communication. Here, microRNAs present in interstitial breast tumor fluids have been analyzed to identify relevant markers for a diagnosis of breast cancer and to elucidate the cross‐talk that exists among cells in a tumor microenvironment. Matched tumor interstitial fluid samples (TIF, n = 60), normal interstitial fluid samples (NIF, n = 51), corresponding tumor tissue specimens (n = 54), and serum samples (n = 27) were collected from patients with breast cancer, and detectable microRNAs were analyzed and compared. In addition, serum data from 32 patients with breast cancer and 22 healthy controls were obtained for a validation study. To identify potential serum biomarkers of breast cancer, first the microRNA profiles of TIF and NIF samples were compared. A total of 266 microRNAs were present at higher level in the TIF samples as compared to normal counterparts. Sixty‐one of these microRNAs were present in > 75% of the serum samples and were subsequently tested in a validation set. Seven of the 61 microRNAs were associated with poor survival, while 23 were associated with the presence of immune cells and adipocytes. To our knowledge, these data demonstrate for the first time that profiling of microRNAs in TIF can identify novel biomarkers for the prognostic classification and detection of breast cancer. In addition, the present findings demonstrate that microRNAs may represent the cross‐talk that occurs between tumor cells and their surrounding stroma.
A technique for multitarget tracking in synthetic aperture radar spotlight imaging mode based on promoted PHD filtering approach
Authors: Daryasafar N. , Sadeghzadeh R. A. , Naser‐Moghadasi M. 
Published: February 2017

AbstractThis paper investigates a new method based on promoted probability hypothesis density (PHD) filtering to simultaneously track several moving targets in data received by synthetic aperture radar (SAR) in spotlight imaging mode. Simultaneous tracking of several targets in the presence of high‐density clutters in environment, as the particular capability of the PHD filter, has turned it into a robust approach in SAR to track moving targets. Given the PHD filter function as a sequence of prediction and update steps, it is more reasonable to apply the approach to the data received by the SAR in spotlight imaging mode; however, according to the specified system parameters, such method is not impossible to be implemented using the Stripmap imaging mode. According to simulation results, applying Range Cell Migration Compensation to the raw data received by SAR before tracking operation results in high‐quality tracking of moving targets.
Hodographic approach for determining spacecraft trajectories through magnetic reconnection diffusion regions
Authors: Shuster J. R. , Argall M. R. , Torbert R. B. , Chen L.‐J. , Farrugia C. J. , Alm L. , Wang S. , Daughton W. , Gershman D. J. , Giles B. L. , Russell C. T. , Burch J. L. , Pollock C. J. 
Published: February 2017

AbstractWe develop an algorithm that finds a trajectory through simulations of magnetic reconnection along which input Magnetospheric Multiscale (MMS) spacecraft observations are matched. Using two‐dimensional particle‐in‐cell simulations of asymmetric reconnection, the method is applied to a magnetopause electron diffusion region (EDR) encountered by the MMS spacecraft to facilitate interpretation of the event based on fully kinetic models. The recently discovered crescent‐shaped electron velocity distributions measured by MMS in the EDR are consistent with simulation distributions at the corresponding time along the computed trajectory.
Derivation and Application of a Generalized Correlation for Mass Transfer in Packed Beds
Authors: Reichelt Erik , Jahn Matthias , Lange Rüdiger 
Published: February 2017

AbstractA generalized correlation for mass transfer in packed beds is developed. It is derived from considerations on single sphere mass transfer. The correlation is validated over a wide range of Reynolds numbers, Schmidt numbers, and bed porosities with literature data. Particular attention is paid to gas‐solid mass transfer at low Reynolds numbers where own experimental results are presented. With the help of the developed correlation, the influence of different bed properties and axial dispersion on mass transfer is discussed.
Resource allocation for full‐duplex–based heterogeneous cellular networks considering back‐haul capacity
Authors: Mardi A. , Azmi P. , Mokari N. , Parsaeefard S. 
Published: February 2017

AbstractIn this paper, we propose a heterogeneous cellular network based on orthogonal frequency division multiple access consisting of full‐duplex femtorelays. Then, we design schemes for the uplink radio resource allocation. The goal of the proposed schemes is to maximize the sum rate, taking into account the back‐haul and transmission power constraints. Moreover, the superiority of the proposed system is shown by comparing it with the half‐duplex femtorelay‐assisted counterpart. Since the proposed resource allocation optimization problem is nonconvex and intractable, we divide it into subcarrier and transmission power allocation subproblems and then use an iterative algorithm to solve each of them. Toward this end, in each iteration, subcarriers are allocated via a binary linear program, while the successive convex approximation method is adapted to transform the nonconvex transmission power allocation subproblem into a sequence of convex subproblems. To achieve this goal, we use 1 of the 3 proposed approaches, namely, dual, arithmetic‐geometric mean approximation, and difference of 2 concave functions. In addition, we investigate the performance, convergence, and computational complexity of these approaches. The simulation results reveal that the proposed approaches are close to the optimal solution while providing less computational complexity. Moreover, they illustrate that even by considering self‐interference in the full‐duplex mode, the sum rate will be increased approximately by 41% in comparison with the half‐duplex mode.
Biochemie: Genetisches Tipp‐Ex für die Landwirtschaft
Authors: Groß Michael 
Published: February 2017

AbstractCrispr‐Cas lässt sich zielgenau an beliebigen Orten der DNA einsetzen. Nun wird die Methode in der Landwirtschaft eingeführt. Aufgrund ihrer molekularen Präzision ist sie sowohl der Genmanipulation des 20. Jahrhunderts als auch der traditionellen Züchtung weit überlegen.
A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum
Authors: Lithgow Karen V. , Hof Rebecca , Wetherell Charmaine , Phillips Drew , Houston Simon , Cameron Caroline E. 
Published: February 2017

AbstractSyphilis is a prominent disease in low- and middle-income countries, and a re-emerging public health threat in high-income countries. Syphilis elimination will require development of an effective vaccine that has thus far remained elusive. Here we assess the vaccine potential of Tp0751, a vascular adhesin from the causative agent of syphilis,Treponema pallidumsubsp.pallidum. Tp0751-immunized animals exhibit a significantly reduced bacterial organ burden uponT. pallidumchallenge compared with unimmunized animals. Introduction of lymph nodes from Tp0751-immunized,T. pallidum-challenged animals to naive animals fails to induce infection, confirming sterile protection. These findings provide evidence that Tp0751 is a promising syphilis vaccine candidate.
Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung
Authors: Dautel Sydney E. , Kyle Jennifer E. , Clair Geremy , Sontag Ryan L. , Weitz Karl K. , Shukla Anil K. , Nguyen Son N. , Kim Young-Mo , Zink Erika M. , Luders Teresa , Frevert Charles W. , Gharib Sina A. , Laskin Julia , Carson James P. , Metz Thomas O. , Corley Richard A. , Ansong Charles 
Published: February 2017

AbstractLung immaturity is a major cause of morbidity and mortality in premature infants. Understanding the molecular mechanisms driving normal lung development could provide insights on how to ameliorate disrupted development. While transcriptomic and proteomic analyses of normal lung development have been previously reported, characterization of changes in the lipidome is lacking. Lipids play significant roles in the lung, such as dipalmitoylphosphatidylcholine in pulmonary surfactant; however, many of the roles of specific lipid species in normal lung development, as well as in disease states, are not well defined. In this study, we used liquid chromatography-mass spectrometry (LC-MS/MS) to investigate the murine lipidome during normal postnatal lung development. Lipidomics analysis of lungs from post-natal day 7, day 14 and 6–8 week mice (adult) identified 924 unique lipids across 21 lipid subclasses, with dramatic alterations in the lipidome across developmental stages. Our data confirmed previously recognized aspects of post-natal lung development and revealed several insights, including in sphingolipid-mediated apoptosis, inflammation and energy storage/usage. Complementary proteomics, metabolomics and chemical imaging corroborated these observations. This multi-omic view provides a unique resource and deeper insight into normal pulmonary development.