bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Mobilisasi Dini Terhadap Penurunan Skala Nyeri Pada Pasien Pasca Operasi Laparatomi Apendisitis Di Rsud Dr. Tjitrowardojo Kelas B Purworejo: Case Report
Authors: Manisa Afrilianti  , Lisa Musharyanti  
Published: September 2024

Apendisitis adalah peradangan yang disebabkan oleh infeksi pada usus buntu dan memerlukan pembedahan atau laparotomi segera. Di dunia masalah kesehatan masyarakat terkait kasus bedah telah meningkat sebesar 10%. Laparotomi adalah prosedur pembedahan yang membuka rongga perut dan dapat dilakukan pada sistem gastrointestinal, saluran kemih, dan ginekologi. Pasien pasca operasi mengalami nyeri akibat kerusakan jaringan dan luka operasi akibat sayatan selama operasi dan nyeri akibat mempertahankan posisi selama operasi dan pasca operasi. Pengobatan nyeri pasca operasi dapat dilakukan dengan terapi farmakologi dan nonfarmakologi. Salah satu pengobatan non farmakologi yang dapat dilaksanakan dan diajarkan kepada pasien adalah mobilisasi dini. Mobilisasi mencegah ketegangan otot sehingga mengurangi rasa nyeri, menjamin kelancaran peredaran darah, memulihkan metabolisme tubuh, mengembalikan fungsi fisiologis organ vital, dan pada akhirnya mempercepat proses penyembuhan luka. Penelitan ini bertujuan untuk mengetahui pengaruh mobilisasi dini terhadap penurunan skala nyeri pada pasien pasca operasi laparatomi apendisitis Di Rsud Dr. Tjitrowardojo Kelas B Purworejo. Metode yang digunakan pada penelitian ini yaitu case repost yang di lakukan selama 3 hari kunjungan pasca operasi laparatomi apendisitis. Hasil penelitaian menunjukan adanya penurunan skala nyeri sebelum dan sesudah dilakukan mobilisasi dini. Skala nyeri pasien pada hari petama dari skala 8 menjadu skala 7, hari kedua dari skala 7 menjadi skala dan pada hari ke tiga dari sekala 5 nenjadi skala 3. Maka kesimpulkan dalam penelitian ini bahwa terdapat pengaruh mobilisasi dini terhadap penurunan skala nyeri pada pasien pasca operasi laparatomi apendisitis
Penerapan Kompres Lidah Buaya Dalam Menurunkan Derajat Feblitis Pada Anak Rawat Inap Di Rsud Pandan Arang Boyolali
Authors: Lady Ayu Febriana  , Ida Nur Imamah  , Panggah Widodo  
Published: September 2024

Data according to the Ministry of Health of the Republic of Indonesia (2020) the incidence of phlebitis in 2020 reached 0.51%. Children are more at risk because children have different physical characteristics and attitudes than adults. From the results of observations and interviews with nurses of the Dadap Serep ward, it was found that the average child who experienced feblitis was children aged 2-6 years. To determine the results of the application of aloe vera compress in reducing the degree of feblitis in inpatients at Pandan Arang Boyolali Hospital. Descriptive research design with a case study approach conducted on 2 respondents and a pretest-posttest research design, the application was carried out 5 times for 20 minutes in two days. The results of the application after applying aloe vera compresses for 2 days were obtained for both respondents to experience a decrease in feblitis degree from the beginning of 2 to 0. There was a change in the degree of feblitis before and after the aloe vera compress from both .
Pengalaman Bonding Attachment Pada Ibu Postpartum Korban Kekerasan Seksual: Case Report
Authors: Istasyafitri Aulia Rahma , Yuni Astuti  , Rusnaningsih  
Published: September 2024

Jumlah kasus kekerasan seksual yang cukup tinggi di Indonesia memiliki dampak fisik maupun psikologis terhadap korban. Pengalaman kehamilan dan persalinan sebagai akibat fisik kejahatan seksual dapat menimbulkan trauma berkepanjangan dan menghambat terjalinnya ikatan yang kuat (bonding attachment) antara ibu dan anak hasil korban kekerasan seksual. Penelitian ini bertujuan untuk mengetahui gambaran bonding attachment pada ibu postpartum korban kekerasan seksual. Metode penelitian yang digunakan yaitu deskriptif dengan desain penelitian studi kasus asuhan keperawatan. Subjek penelitian ini adalah seorang ibu postpartum yang melahirkan seorang anak hasil pemerkosaan. Instrumen pengkajian menggunakan Postpartum Bonding Questionnaire (PBQ) yang berisi 25 item pertanyaan yang dibagi menjadi empat dimensi pertanyaan. Hasil penelitian menunjukkan pada pengkajian hari pertama postpartum skor bonding attachment sebesar 36. Setelah dilakukan follow-up di hari keenam, terjadi penurunan skor bonding attachment menjadi 14. Semakin rendah skor semakin baik bonding attachment yang terjadi. Studi kasus ini menunjukkan adanya bonding attachment yang baik pada ibu korban pemerkosaan dengan bayinya.
Penerapan Pembelajaran Berdiferensiasi Berbasis Proyek Dalam Implementasi Kurikulum Merdeka pada Pembelajaran Bahasa Arab
Authors: Ma’wa Auladatil , Suparmanto  , Abdurrahman Azmy , Najwa Dewi Qotrun Nada , Karim Syauqi Miftahul 
Published: September 2024

Phenomena in Arabic language teaching found in the field show students' difficulties in understanding and applying Arabic language interpretations. One of the reasons for this is that the learning provided does not pay attention to each student's abilities, so it does not provide learning according to the needs of each student. This learning difficulty is also caused by monotonous learning, which causes students to lack interest and motivation in learning Arabic. Purpose: The aim of this research is to analyze the application of project-based differentiated learning in the implementation of the independent curriculum in Arabic language learning at MTs NW Mercapada. Method: The research uses descriptive qualitative methods. Results and Discussion: By implementing project-based differentiated learning in this research, it shows positive results in increasing students' understanding of mufrodat in Arabic language learning at MTs NW Mercapada
The Influence of Pop Up Book Media on the Mastery of Mufradat for Grade IV Students Mis Al-Mubarakah Mohiyolo
Authors: Daud Siska , Hairuddin  , M. Mooduto Dzulkifli 
Published: September 2024

This study aims to determine the influence of the use of Pop Up Book media in learning Arabic in grade IV, especially in students' mastery of mufradat. The research was conducted at MIS Al-Mubarakah Mohiyolo by involving grade IV students as research subjects. The research method used is an experiment with a quantitative approach with a quasi-experimental design, which can compare the conditions before and after the treatment. Data was collected through pre-test and post-test tests to measure students' mastery of mufrodat. The results of the data analysis showed that there was a significant influence of the use of Pop Up Book media on students' mastery of mufrodat. This can be seen from the results of the hypothesis test using the Mann-Whitney test obtained a significance value (2-tiled) < 0.05, so there is a significant influence on the experimental class. So it can be concluded that the hypothesis is accepted.
Waralaba Franchiese di Indonesia
Authors: Adelina Murti Syafiina  , Rusnandari Retno Cahyani  
Published: September 2024

Franchise is a form of business partnership in which the owner of a brand or business concept (franchisor) gives permission to another party (franchisee) to use and manage their business in accordance with predetermined guidelines. This involves exchanging the right to pay initial fees, royalties, or other fees or special rights owned by individuals or business entities to a business system with business characteristics in order to market goods or services that have proven successful and can be utilized or used by other parties. based on a franchise agreement. A franchise must have a legal basis which is part of the agreement or contract. To avoid undesirable things, before being bound by a franchise agreement, each party involved must pay attention to each point in the franchise agreement carefully and thoroughly. Therefore, the franchise agreement is a very important part of the franchise business.
Analisis Pemahaman Quality Assurance pada Mahasiswa Bisnis Digital Universitas Pendidikan Indonesia
Authors: Gieldy Akhyat Affandi Utama  , Adam Hermawan  , Adi Prehanto  
Published: September 2024

Digital Business students at Universitas Pendidikan Indonesia Tasikmalaya Campus recognize the importance of Quality Assurance (QA), but many do not fully grasp the concept. This study aims to describe and evaluate students’ understanding of QA, with the goal of bridging the gap between awareness and application in the field of Digital Business. The research method used is descriptive quantitative, employing a Probability Sampling technique with a Proportionate Stratified Random Sampling approach. Results indicate that students generally have a good understanding of QA, especially in grasping basic concepts and the significance of QA for product quality. However, some dimensions of QA remain less understood, particularly regarding practical application in the industry. The depth of understanding varies; most students have a sufficient basic grasp, but only a few can relate QA concepts to real-world case studies. Based on these findings, the Digital Business Study Program is advised to integrate practical elements into the QA curriculum, such as QA simulations, industry case studies, and collaborative projects with companies. This is expected to enhance students’ understanding and bridge the gap between QA theory and practice. Future research could test the effectiveness of various QA teaching approaches and compare understanding across different study programs.

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Analisis Faktor-Faktor yang Mempengaruhi Keputusan Pembelian Online di Marketplace Shopee
Authors: Alfin Muslikhun  , Sutopo Sutopo  
Published: September 2024

This study aims to analyze the factors that support the increase in online purchasing decisions in the Shopee marketplace. These factors consist of Online Customer Rating, Online Customer Review, Price, and Free Shipping. The population in this study were all Shopee user consumers with an unlimited number. While the sample used was all Shopee user consumers in the Gunungpati area and its surroundings which were calculated using the lemeshow formula and obtained 100 respondents. The results of hypothesis testing state that the four variables (Online Customer Rating, Online Customer Review, Price, and Free Shipping) have an influence on online purchasing decisions in the shopee marketplace both partially and simultaneously. Testing the coefficient of determination produces findings where the variables online customer rating, online customer review, price, free shipping are able to influence online purchasing decisions in the Shopee application by 89.5%. While the remaining 10.5% is influenced by other variables.

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Evaluation of Public Response to e-PR Implementation by PT KAI: A Case Study of Service Satisfaction and Effectiveness
Authors: Lisdiantini Netty , Azis Aminudin , Subiyantoro Subiyantoro , Surya Pratama Hudha 
Published: September 2024

This research aims to evaluate the public response to the implementation of the e-PR service by PT. KAI, focusing on service satisfaction and effectiveness. In the context of public service digitalization, PT. KAI has taken an innovative step by introducing e-PR, an electronic public relations platform, to enhance engagement and communication with the public. Through online surveys , this study will collect user perception data related to the quality, accessibility, and benefits of the e-PR service. Data analysis will be conducted using descriptive and inferential statistical techniques to identify levels of satisfaction and factors influencing the effectiveness of e-PR. The results of this study are expected to provide valuable insights for PT. KAI in refining its digital communication strategy and improving service quality to the public. Thus, this research is not only relevant to PT. KAI but also to digital PR practices in other industries
Juridical Analysis Of Proof Elements Harm State Finance In Criminal Actions Corruption In Indonesia
Authors: Andre Yosua M  , Tegar Mulia  
Published: September 2024

Policies that are often taken by public officials sometimes give rise to major criticism committing a pattern of criminal acts of corruption. Policies that are considered can fall into the action category corruption is policies that could harm state finances. So it's a loss State finances are one of the elements of criminal acts of corruption in Article 2 paragraph (1) and Article 3 Act No. 31 Year 1999 jo Act No. 20 Year 2001 about Eradication Act Criminal Corruption. The formulation of elements that are detrimental to state finances in these two articles is at the evidentiary level still raises various obstacles because it is an unclear and unclear norm multiple interpretations. Results from study show that prove that element harm state finances in criminal acts of corruption are still understood as formal criminal acts so that the proof Enough with fulfil deed the And No need There is consequence, Good Which potential harm finance country nor loss Which Actually, perpetrator can convicted. After Court Constitution through Decision Number 25/PUU-XIV/2016 mention that the word "can" in Article 2 paragraph (1) and Article 3 is unconstitutional and is fundamentally change qualification corruption become become crime material, However in its implementation There are different views regarding law enforcement officials in proving that element This is detrimental to state finances, giving rise to legal uncertainty. In the upcoming corruption criminal law reform, the more appropriate model of proof is with use draft loss finance country in meaning crime material. Through draft This, something deed new can seen fulfil elements follow criminal corruption with condition There must be a result of the state's loss being real and occurring (actual). lost). Proof concept loss state finances in meaning material ensure law Which fair certainty.
EDUKASI SEKSUALITAS BAGI REMAJA
Authors: Lukas Jesica , Namangge Lini , Makalikis Kezya , Ilat Irene  Preisilia 
Published: September 2024

Pendidikan seks hendaknya diberikan sejak dini, sebagai persiapan menghadapi perubahan pada diri sendiri dan lingkungan. Pendidikan seks pada remaja sangat penting untuk memahami informasi seksual, memiliki kesadaran akan pentingnya memahami masalah seksual, memahami fungsi seksualitas, dan mengatasi masalah seksual pada remaja. Pendidikan seks pada remaja juga membantu mencegah permasalahan seksual,seperti hubungan seks pranikah atau hubungan seks di luar nikah, yang dapat menimbulkan dampak negatif seperti buruknya kesehatan, menurunnya kesehatan reproduksi, dan risiko penyakit menular seksual. Pendidikan seks pada remaja juga mengarahkan remaja pada rendahnya pengetahuan tentang kesehatan reproduksi, khususnya dalam hal melindungi diri dari risiko kesehatan reproduksi. Tingkat pengetahuan remaja Indonesia mengenai kesehatan reproduksi masih rendah, khususnya dalam hal melindungi diri dari risiko kesehatan reproduksi. Pendidikan seks pada remaja diperlukan untuk mencegah kebingungan pada masa peralihan dari masa kanak-kanak ke masa dewasa. Pendidikan seks pada remaja juga diperlukan untuk melindungi organ reproduksi pada tubuhnya dan mencegah orang lain menyentuh organ reproduksinya, khususnya pada remaja perempuan. Pada artikel kali ini kita akan membahas tentang pentingnya pendidikan seks bagi remaja, faktor-faktor yang mempengaruhi pendidikan seks di kalangan remaja, dan dampak yang dialami remaja ketika melakukan hubungan seks pranikah atau hubungan seks di luar nikah
Preparation of transferrin-targeted temozolomide nano-micelles and their anti-glioma effect
Authors: Yu Jun , Xue Yonghua 
Published: September 2024

Objectives
This study aims to develop brain-targeted temozolomide (TMZ) nanograins using the biodegradable polymer material PEG-PLA as a carrier. The model drug TMZ was encapsulated within the polymer using targeted nanotechnology. Key characteristics such as appearance, particle size, size distribution, drug loading capacity, in vitro release rate, stability, and anti-tumor effects were systematically evaluated through in vitro experiments.

Methods
Transmission electron microscopy (TEM) and Malvern size analyzer were employed to observe the morphological and particle size features of the TMZ nanospheres at various time points to assess stability. The effects of TMZ nanograins on glioma cell viability and apoptosis were evaluated using MTT assays and flow cytometry.

Results
The targeted TMZ nano-micelles were successfully synthesized. After loading and targeted modifications, the particle size increased from 50.7 to 190 nm, indicating successful encapsulation of TMZ. The average particle size of the nano-micelles remained stable around 145 ± 10 nm at 1 day, 15 days, and 30 days post-preparation. The release rate of the nano-micelles was monitored at 2 h, 12 h, 24 h, and 48 h post-dialysis, ultimately reaching 95.8%. Compared to TMZ alone, the TMZ-loaded PEG-PLA nano-micelles exhibited enhanced cytotoxicity and apoptosis in glioma cells. This was accompanied by increased mitochondrial membrane potential and reactive oxygen species (ROS) levels following treatment with the TMZ nano-micelles.

Conclusions
TMZ-loaded nano-micelles demonstrated a gradual release profile and significantly enhanced inhibitory effects on human glioma U251 cells compared to TMZ alone. The findings suggest that TMZ-loaded PEG-PLA nano-micelles may offer a more effective therapeutic approach for glioma treatment.
Evaluation of Fertigation and Foliar Spray of Nutrients for the Performance of Bottle Gourd [Lagenaria siceraria (Molina) Standl.] on Yield, Quality and Economics
Authors: Sarap P.A. , Hadole S. S. , Sarode M.D. , Reddy Y. A. , Parmar J. N. , Dangore S. T. , Nandukar S.D. , Shukla Prashant 
Published: September 2024

The field experiment entitled “Evaluation of fertigation and foliar spray of nutrients for the performance of bottle gourd [Lagenaria siceraria (Molina) Standl.] on yield, quality and economics” was conducted during Kharif season from 2020-21 to 2022-2023 at Chilli and Vegetable Research Unit, Dr. Panjabrao Deshmukh Krishi Vidyapeeth, Akola (Maharashtra). The site is Situated in the subtropical region at 22042’ North latitude and 77002’ East longitude and at an altitude of 307.42 m above mean sea level with average annual precipitation was 944.4 mm. Experimental field is situated at the latitude of 200 40' 35'' North and longitude of 760 59' 10'' East. The experiment was laid out in factorial randomized block design with twelve treatments combinations and three replications. The two factors i.e., fertigation levels and foliar spray levels i.e. soil application with S₁ (200:100:100 kg ha-1) NPK through fertigation in ten equal doses along with two foliar spray of F3 (ZnSO4 @ 0.25% + FeSO4 @ 0.25%) at flower initiation and fruit setting (S₁F3) was found better for maximum highest yield and B:C ratio (2.17) of bottle gourd followed by statistically at par with the treatment with (S2F3) soil application of S2 (150:75:75 kg ha-1) NPK through fertigation in ten equal doses along with foliar application of F3 (ZnSO4 @ 0.25% + FeSO4 @ 0.25%) at flower initiation and fruit setting. Similarly, the quality parameters like reducing, non -reducing sugars (g/100g) and ascorbic acid content (%) were significantly improved with fertigation level of S₁ (200:100:100) kg NPK along with foliar spray of F3 (foliar spray of ZnSO4 @ 0.25% + FeSO4 @ 0.25%).
Patient Knowledge and Utilization of Over-the-Counter (OTC) Medications: A Comprehensive Study
Authors: Amjad Umair , Ali Wasiq , Rehman Talha , Aamir Muhammad , Shahzadi Mahnoor , Abdullah  , Saeed Muhammad Ahmed , Sabri M. Sohaib Sultan , Salah Adeel , Qaisar Mahnoor , Iqbal Muhammad Zahid 
Published: September 2024

Background: Over-the-Counter (OTC) medications are the drugs that do not require prescription. In earlier times, self-medication of OTC drugs was not considered a healthy practice. But now FDA stated that “when these medications are used according to guidelines, they are considered safe and effective”. Although along with the potential benefits over-use and miss-use is considered harmful and can cause potential side effects.
Objective: The research is carried out with objective to assess patient knowledge regarding OTC medicines use pattern, potential side effects and interactions.
Methods: The cross-sectional, observational study was conducted in different cities of Punjab, Pakistan. Data was collected on validated questionnaire after getting consent from 162 patients. And SPSS version 26 was used for statistical analysis of the collected data. Patients below 18 years of age were excluded from the study.
Results: A total of 162 patients participated in the current study. A statistically non-significant association was observed between the participants' gender and their level of knowledge regarding OTC medication, with a p-value of 0.442. However, a statistically significant association was found between having healthcare providers among family members and knowledge about OTC medication, with a p-value of 0.015 and an effect size of 0.008, indicating a weak positive association. Additionally, geographical location demonstrated a direct positive effect, with a p-value of 0.001 and an effect size of 0.330, which reflects a moderate positive association according to Cohen's classification.
Conclusion: Gender does not affect overall knowledge of OTC medications; however, education has a direct impact on understanding and using medications. Among the sources of information regarding OTC medications, healthcare providers within family members are identified as the most significant source.
Polar tongue of ionization (TOI) and associated Joule heating intensification investigated during the magnetically disturbed period of 1–2 October 2001
Authors: Horvath Ildiko , Lovell Brian C. 
Published: June 2016

AbstractWe investigate storm‐enhanced density (SED) and polar tongue of ionization (TOI) over North America under southward Interplanetary Magnetic Field conditions. We focus on the 30 September to 1 October 2001 medium magnetic storm's recovery phase (Period 1) and on the last substorm (Period 2) of the following 2 October substorm series. We aim to study the SED‐TOI structure in the time frame of solar wind energy input to the magnetosphere‐ionosphere system and in terms of Joule heating. We utilize GPS total electron content maps tracking SED plume and polar TOI, and spectrogram images detecting polar rain and precipitation void and thus evidencing dayside merging. The variations of merging electric (E) field (EM) and its mapped‐down polar equivalent (EP), energy input efficiency (EIeff), and modeled Joule heating rate (QJoule) are monitored. Results show multiple Joule heating intensification points implying multiple energy deposition points at high latitudes where the magnetic pole was one of the preferred locations. During the higher EIeff (~1.5%) Period 2, the polar TOI was associated with a well‐defined strong QJoule intensification and with polar rain (or void) on the dayside (or nightside). During the lower EIeff (~0.5%) Period 1, only weak QJoule intensification occurred in the absence of both polar TOI and polar rain. We highlight the polar TOI's potential impact on the thermosphere. We conclude that (i) strong (EM ≈ 5 mV/m during Period 2) or weak (EM ≈ 0.5–2 mV/m during Period 1) EM facilitated energy deposition close to the magnetic pole and (ii) EIeff could be used as a diagnostic of the polar TOI's intensity.