bluuebunny/crossref_metadata_2025_split huggingface dataset:
Absorbed dose estimates from a single measurement one to three days after the administration of 177Lu-DOTATATE/-TOC
Authors: Lapa Constantin , Buck Andreas , Lassmann Michael , Werner Rudolf , Hänscheid Heribert 
Published: November 2017

SummaryAim: To retrospectively analyze the accuracy of absorbed dose estimates from a single measurement of the activity concentrations in tumors and relevant organs one to three days after the administration of 177Lu-DOTA-TATE/TOC assuming tissue specific effective half-lives. Methods: Activity kinetics in 54 kidneys, 30 neuroendocrine tumor lesions, 25 livers, and 27 spleens were deduced from series of planar images in 29 patients. After adaptation of mono- or bi-exponential fit functions to the measured data, it was analyzed for each fit function how precise the time integral can be estimated from fixed tissue-specific half-lives and a single measurement at 24, 48, or 72 h after the administration. Results: For the kidneys, assuming a fixed tissue-specific half-life of 50 h, the deviations of the estimate from the actual integral were median (5 % percentile, 95 % percentile): -3 °% (-15 %>; +16 °%) for measurements after 24 h, +2 %> (-9 %>; +12 %>) for measurements after 48 h, and 0 % (-2 %; +12 %) for measurements after 72 h. The corresponding values for the other tissues, assuming fixed tissue-specific half-lives of 67 h for liver and spleen and 77 h for tumors, were +2 % (-25 %; +20 %) for measurements after 24 h, +2 °% (-16 %>; +17 %>) for measurements after 48 h, and +2 %> (-11 %>; +10 %>) for measurements after 72 h. Conclusions: Especially for the kidneys, which often represent the dose limiting organ, but also for liver, spleen, and neuroendocrine tumors, a meaningful absorbed dose estimate is possible from a single measurement after 2, more preferably 3 days after the administration of 177Lu-DOTA-TATE/-TOC assuming fixed tissue specific effective half-lives.
Réflexions sur la notion de vide à partir du travail du négatif
Authors: Aloupis Panos 
Published: November 2017

L’auteur s’interroge sur les liens entre les notions de vide et de négatif. Dans la première partie, il prend appui sur deux conférences publiées de Green sur Winnicott et Bion en rapport avec le travail du négatif ; dans la deuxième partie ce rapport sera abordé à l’aide d’une vignette clinique et d’un article de Green au sujet de la clinique psychosomatique.
L’accompagnement global par les sages-femmes
Authors: Thomas Catherine 
Published: November 2017

L’institutionnalisation et le développement des technologies biomédicales concernant la prise en charge de la grossesse et de l’accouchement imposent aux femmes et aux professionnels de santé qui les accompagnent un grand nombre de « recommandations » basées sur un principe de prévention du risque. Les sages-femmes qui pratiquent l’accompagnement global se positionnent à contre-courant de cette standardisation de l’encadrement de la périnatalité. Leur regard critique sur le système hospitalier et les effets iatrogènes de la médicalisation les amène à répondre à la demande de femmes en recherche d’une réappropriation des conditions de la naissance. Ainsi elles participent plus largement à une dynamique de démocratisation sanitaire visant à mettre leur expérience et celle des parturientes au cœur d’une réflexion sur l’efficacité des techniques de prévention et de gestion des risques.
Breast Involvement by Hematologic Malignancies: Ultrasound and Elastography Findings with Clinical Outcomes
Authors: Aslan Hulya , Pourbagher Aysin 
Published: November 2017

Objective:
Hematological malignancies very rarely involve the breast. The aim of this study is to retrospectively evaluate B-mode ultrasound (US) and elastography (ES) findings of breast involvement by hematologic malignancies with clinical outcomes.

Materials and Methods:
All core-needle biopsy results that were performed at our tertiary breast center from January 2013 to September 2016 were searched. Our search revealed 9 patients with breast involvement either by leukemia or lymphoma. All patients were examined using B-mode US and ES. US and ES findings were analyzed with the consensus of two radiologists, and clinical outcomes were noted.

Results:
The mean age of the study population was 41.6 years (range, 20–83 years). Two patients showed diffuse hypoechoic parenchymal infiltration. The elasticity assessments of these lesions were soft and intermediate. The remaining 7 patients had mass lesions. The elasticity assessment of these masses according to Breast Imaging Reporting and Data System US was as follows: Soft (n = 1), intermediate (n = 4), high (n = 2).

Conclusions:
It is important to consider that hematologic malignancies may appear as soft or intermediate lesions on ES. Patients’ history and clinical background should help us to consider breast involvement. In addition, the clinical outcomes may not be related with elasticity assessments.
Persoonsdeixis in het zuidelijk Bargoens van de negentiende en de twintigste eeuw
Authors: Van Hauwermeiren Paul 
Published: November 2017

Abstract

Person deixis in southern Dutch Cant of the nineteenth and twentieth century

The dialects of Dutch Cant (Bargoens) spoken in the Low Countries south of the great rivers used a specific person deixis. The speaker and the addressee were not referred to by means of pronouns, as in standard Dutch, but by means of lexicalized nominal markers. Nominal person deixis, however, is less suitable for differentiation than pronominal deixis and so tends to make reference to the addressee less precise – which contributes to the deliberate incomprehensibility that a secret group language such as Dutch Cant seeks after.
This article presents a linguistic description of person deixis as found in the dialects of younger southern Dutch Cant. Most of these dialects no longer being spoken, we can describe them only on the basis of sources which have preserved them. For at least twenty dialects such written sources are available. However, apart from a few exceptions these sources are mere lists of Cant words in which examples of specific person deixis are few and far between. To establish the system of person deixis in a given Cant dialect, we need texts written in that dialect, dialogues with sentences and references to speaker and addressee. There are no texts with an adequate number of occurrences of person deixis that might make an exhaustive description of the whole domain possible, since the domain of person deixis also covers possessive and reflexive constructions as well as non-specific person deixis. The only dialects for which longer texts in younger southern Dutch Cant are available are those of Zele in the province of East-Flanders (Belgium) and the Groenstraat in Landgraaf in the southern province of Limburg (the Netherlands).
The article describes the differences between person deixis in Standard Dutch and in the dialects of younger southern Cant. To this end the available source material is used. On the basis of some fifty lists of Cant words it is shown which person markers are used in which dialects. Person deixis in the Cant of Zele and of the Groenstraat in Landgraaf is described as exhaustively as possible by the sole means of sentences from the texts available for these two places.
Possessor truncation in kinship terms in Dutch dialects
Authors: Postma Gertjan 
Published: November 2017

Abstract

Possessor truncation in kinship terms in Dutch dialects

In this study we report a hardly noticed, poorly studied, and non-understood property of kinship terms in many Dutch dialects: a distinct, more impoverished possessor inflection in kinship terms, which was coined “possessor truncation” in Goeman et al. (2008). After reporting dialect-geographical, diachronic, and morphological properties of possessor truncation, we give a morphosyntactic account inspired on determiner drop in kinship terms in Italian. Possessor truncation in Dutch and determiner drop in Italian can be unified under the assumption that kinship terms generate their referential role within in the sub-lexical domain, while ordinary nouns merge these argumental properties in the supra-lexical domain.
Verbreiding en oorzaak van h-procope en h-prothese in het Middelnederlands
Authors: Rem Margit , van der Sijs Nicoline , van Os Marjolein 
Published: November 2017

Abstract

The diffusion and cause of procope and prothesis of h in Middle Dutch

In this article we examine the geographical distribution of procope and prothesis of h in Dutch charters from the 13th and 14th centuries, and the frequency with which these phenomena occur, while trying to find patterns in the data. We then venture an explanation of why these phenomena originate in the Flemish dialects. Our hypothesis is that procope of h was induced by language contact between Dutch (Flemish) and French, due to the many bilinguals in Flanders. The contact situation triggered an already existing internal tendency by which h was lost or weakened before sonorants and glides to also affect prevocalic h.
Household Waste Generating Factors and Composition Study for Effective Management in Gorkha Municipality of Nepal
Authors: Maskey Bijan , Singh Mrinila 
Published: November 2017

Municipal solid waste is a growing concern in cities of developing countries and households are the main contributor. Lack of reliable data sources remain one of the major drawbacks for deciding on effective waste management option. The study area Gorkha municipality is selected because it is one of the highly under-researched and least resource intensive municipalities in Nepal. However, continued growth in municipal waste if left unattended will only intensify the problem and thus demands proactive action. Therefore, the objective of this study is to analyze waste composition and to evaluate the socioeconomic factors impacting household waste generation for effective management. Using stratified sampling method, 401 households were selected from all 15 municipal wards. Socioeconomic factors impacting household waste generation were assessed using Ordinary Least Square regression model. The rate of household waste generation in Gorkha municipality is found to be 0.24 kg/capita/day and estimated total household waste generation of 9.4 tonnes/day. Household size and income are found to have positive impact on waste generation, both statistically significant at 1% and thus can be important indicators to forecast solid waste generation trend. Household waste composition was 47.25% organic waste, 37.52% recyclable waste that comprised of 10.38% paper and paper products, 9.88% glass, 6.92% metal, 5.39% plastic, 3.57% textile and 1.38% rubber and leather, and rest 15.23% other waste. Organic waste has the highest share and if not managed properly, creates serious health and environmental hazards. It could be managed efficiently by composting at household and local government level.
The Updated World Health Organization Glioma Classification: Cellular and Molecular Origins of Adult Infiltrating Gliomas
Authors: Pisapia David J. 
Published: November 2017

Context.—
In the recently updated World Health Organization (WHO) classification of central nervous system tumors, our concept of infiltrating gliomas as a molecular dichotomy between oligodendroglial and astrocytic tumors has been codified. Advances in animal models of glioma and a wealth of sophisticated molecular analyses of human glioma tissue have led to a greater understanding of some of the biologic underpinnings of gliomagenesis.

Objective.—
To review our understanding of gliomagenesis in the setting of the recently updated WHO classification of central nervous system tumors. Topics addressed include a summary of an updated diagnostic schema for infiltrating gliomas, the crucial importance of isocitrate dehydrogenase mutations, candidate cells of origin for gliomas, environmental and other posited contributing factors to gliomagenesis, and the possible role of chromatin topology in setting the stage for gliomagenesis.

Data Sources.—
We conducted a primary literature search using PubMed.

Conclusions.—
With multidimensional molecular data sets spanning increasingly larger numbers of patients with infiltrating gliomas, our understanding of the disease at the point of surgical resection has improved dramatically and this understanding is reflected in the updated WHO classification. Animal models have demonstrated a diversity of candidates for glioma cells of origin, but crucial questions remain, including the role of neural stem cells, more differentiated progenitor cells, and glioma stem cells. At this stage the increase in data generated from human samples will hopefully inform the creation of newer animal models that will recapitulate more accurately the diversity of gliomas and provide novel insights into the biologic mechanisms underlying tumor initiation and progression.
Controllability of Surface Water Networks
Authors: Riasi M. Sadegh , Yeghiazarian Lilit 
Published: November 2017

AbstractTo sustainably manage water resources, we must understand how to control complex networked systems. In this paper, we study surface water networks from the perspective of structural controllability, a concept that integrates classical control theory with graph‐theoretic formalism. We present structural controllability theory and compute four metrics: full and target controllability, control centrality and control profile (FTCP) that collectively determine the structural boundaries of the system's control space. We use these metrics to answer the following questions: How does the structure of a surface water network affect its controllability? How to efficiently control a preselected subset of the network? Which nodes have the highest control power? What types of topological structures dominate controllability? Finally, we demonstrate the structural controllability theory in the analysis of a wide range of surface water networks, such as tributary, deltaic, and braided river systems.
Pseudohalide‐Induced Recrystallization Engineering for CH3NH3PbI3 Film and Its Application in Highly Efficient Inverted Planar Heterojunction Perovskite Solar Cells
Authors: Dong Hua , Wu Zhaoxin , Xi Jun , Xu Xiaobao , Zuo Lijian , Lei Ting , Zhao Xingang , Zhang Lijun , Hou Xun , Jen Alex K.‐Y. 
Published: November 2017

AbstractHigh crystallinity and compactness of the active layer is essential for metal‐halide perovskite solar cells. Here, a simple pseudohalide‐induced film retreatment technology is developed as the passivation for preformed perovskite film. It is found that the retreatment process yields a controllable decomposition‐to‐recrystallization evolution of the perovskite film. Corresponding, it remarkably enlarges the grain size of the film in all directions, as well as improving the crystallinity and hindering the trap density. Meanwhile, owing to an intermediate catalytic effect of the pseudohalide compound (NH4SCN), no crystal orientation changing and no impurity introduction in the modified film. By integrating the modified perovskite film into the planar heterojunction solar cells, a champion power conversion efficiency of 19.44% with a stabilized output efficiency of 19.02% under 1 sun illumination is obtained, exhibiting a negligible current density–voltage hysteresis. Moreover, such a facile and low‐temperature film retreatment approach guarantees the application in flexible devices, showing a best power conversion efficiency of 17.04%.
Synthesis of Low‐Dimensional Polyion Complex Nanomaterials via Polymerization‐Induced Electrostatic Self‐Assembly
Authors: Ding Yi , Cai Meng , Cui Zhigang , Huang Leilei , Wang Lei , Lu Xinhua , Cai Yuanli 
Published: November 2017

AbstractNanostructured polyion complexes (PICs) are appealing in biomaterials applications. Yet, conventional assembly suffers from the weakness in scale‐up and reproducibility. Only a few low‐dimensional PICs are available to date. Herein we report an efficient and scalable strategy to prepare libraries of low‐dimensional PICs. It involves a visible‐light‐mediated RAFT polymerization of ionic monomer in the presence of a polyion of the opposite charge at 5–50 % w/w total solids concentration in water at 25 °C, namely, polymerization‐induced electrostatic self‐assembly (PIESA). A Vesicle, multi‐compartmental vesicle, and large‐area unilamellar nanofilm can be achieved in water. A long nanowire and porous nanofilm can be prepared in methanol/water. An unusual unimolecular polyion complex (uPIC)‐sphere‐branch/network‐film transition is reported. This green chemistry offers a general platform to prepare various low‐dimensional PICs with high reproducibility on a commercially viable scale under eco‐friendly conditions.
Total Synthesis of (+)‐Sarcophytin
Authors: Nannini Leonardo J. , Nemat Suren J. , Carreira Erick M. 
Published: November 2017

AbstractA total synthesis of the cembranoid (+)‐sarcophytin is presented, featuring a Diels–Alder cycloaddition of an enone as the dienophile with an ester‐derived dienoate. The study highlights a peculiar geometric preference for the Z dienoate to furnish the cycloadduct. The endgame involves a reaction cascade, including lactone opening, alcohol oxidation, and ketone epimerization to complete an efficient synthesis. A salient feature of the synthesis is the resulting reassignment of the absolute configuration, which corrects the previously reported nominal structure.
A Water‐Driven Triboelectric Generator for Electrocatalytic Wastewater Treatment
Authors: Kushwaha Himmat S. , Kumar Anuruddh , Kumar Rajeev , Vaish Rahul 
Published: November 2017

AbstractTriboelectric generators (TEGs) have been shown to be advantageous at energy harvesting for sensors and portable devices. Here, a water‐driven triboelectric generator (WD‐TEG) powered wastewater treatment reactor that harvests energy from the water flow via the triboelectric effect is introduced. The WD‐TEG is an efficient and green approach towards wastewater treatment. With the electricity generated from WD‐TEG, a degradation efficiency of up to 80 % for estrogenic pollutants, estriol, and 17‐β estradiol is achieved within just 150 min. The effect of water rotation on degradation rate is also investigated. The observed results show that triboelectric coupled electrochemical systems can be promising solution for wastewater treatment.
Modelling soil moisture in a high‐latitude landscape using LiDAR and soil data
Authors: Kemppinen Julia , Niittynen Pekka , Riihimäki Henri , Luoto Miska 
Published: November 2017

AbstractSoil moisture has a pronounced effect on earth surface processes. Global soil moisture is strongly driven by climate, whereas at finer scales, the role of non‐climatic drivers becomes more important. We provide insights into the significance of soil and land surface properties in landscape‐scale soil moisture variation by utilizing high‐resolution light detection and ranging (LiDAR) data and extensive field investigations. The data consist of 1200 study plots located in a high‐latitude landscape of mountain tundra in north‐western Finland. We measured the plots three times during growing season 2016 with a hand‐held time‐domain reflectometry sensor. To model soil moisture and its temporal variation, we used four statistical modelling methods: generalized linear models, generalized additive models, boosted regression trees, and random forests. The model fit of the soil moisture models were R2 = 0.60 and root mean square error (RMSE) 8.04 VWC% on average, while the temporal variation models showed a lower fit of R2 = 0.25 and RMSE 13.11 CV%. The predictive performances for the former were R2 = 0.47 and RMSE 9.34 VWC%, and for the latter R2 = 0.01 and RMSE 15.29 CV%. Results were similar across the modelling methods, demonstrating a consistent pattern. Soil moisture and its temporal variation showed strong heterogeneity over short distances; therefore, soil moisture modelling benefits from high‐resolution predictors, such as LiDAR based variables. In the soil moisture models, the strongest predictor was SAGA (System for Automated Geoscientific Analyses) wetness index (SWI), based on a 1 m2 digital terrain model derived from LiDAR data, which outperformed soil predictors. Thus, our study supports the use of LiDAR based SWI in explaining fine‐scale soil moisture variation. In the temporal variation models, the strongest predictor was the field‐quantified organic layer depth variable. Our results show that spatial soil moisture predictions can be based on soil and land surface properties, yet the temporal models require further investigation. Copyright © 2017 John Wiley & Sons, Ltd.
Tracking trachyte on the Roman routes: Provenance study of Roman infrastructure and insights into ancient trades in northern Italy
Authors: Germinario Luigi , Zara Arturo , Maritan Lara , Bonetto Jacopo , Hanchar John M. , Sassi Raffaele , Siegesmund Siegfried , Mazzoli Claudio 
Published: November 2017

AbstractRoman colonization of northern Italy during the late Republican Age brought about significant building activity in the newly acquired territories, involving the construction of new infrastructure that demanded large amounts of stone. Trachyte of the Euganean Hills was among the most commonly used materials for building roads, bridges, forum squares, and aqueducts. This paper addresses the recognition of the provenance quarry of Euganean trachyte used in Roman public infrastructure in northeastern Italy. Petrographic features and major‐ and trace‐element composition of bulk rock and phenocrysts, analyzed by X‐ray fluorescence (XRF) and laser ablation inductively coupled plasma mass spectrometry (LA‐ICPMS), were used as provenance tracers. The provenance determinations allow for exploring the commercial, political, and economic dynamics involving the supply of trachyte for public works, and the management of Roman quarries, which likely were in competition with each other and separately controlled by the most important nearby cities. Finally, broad insights into ancient trades in northern Italy and the main routes of stone distribution are discussed: most transport was done by ship, being more rapid and less costly, taking advantage of the Adriatic Sea, the Po River, and the many waterways close to the Euganean quarries.
Conservative management of placenta percreta
Authors: Matsuzaki Shinya , Yoshino Kiyoshi , Endo Masayuki , Kakigano Aiko , Takiuchi Tsuyoshi , Kimura Tadashi 
Published: November 2017

AbstractBackgroundMaternal outcomes after conservative management of placenta percreta are poorly understood.ObjectiveTo assess the success and complication rates of conservative management of placenta percreta.Search strategyThe PubMed, MEDLINE, and Scopus databases were searched for English‐language articles published between January 1990 and December 2016, using combinations of search terms related to conservative management of placenta percreta.Selection criteriaOnly studies describing conservative treatment for placenta percreta (without placental removal) were included in the systematic review.Data collection and analysisThere were 44 studies included and maternal outcomes were reviewed and categorized among 72 patients.Main resultsThe uterus was preserved among 42 (58%) patients and severe complications developed among 40 (56%). Prophylactic uterine artery embolization (UAE) did not improve success rates (P=0.807); however, the mean time for complete placental resorption was lower in the UAE group than in the non‐UAE group (22.4 weeks vs 35.3 weeks; P=0.014). Hysterectomy was performed at a mean of 44.6 days after cesarean delivery. Among the 23 patients with hysterectomy‐related complications, 18 (78%) experienced bladder injury, intraoperative bleeding (>2000 mL), or both. The use of chemotherapy did not improve success rates (P=0.064).ConclusionsThe present systematic review revealed high maternal morbidity during conservative management of placenta percreta.