bluuebunny/crossref_metadata_2025_split huggingface dataset:
The quality of equality: thinking differently about gender inclusion in organizations
Authors: Adamson Maria , Kelan Elisabeth K. , Lewis Patricia , Rumens Nick , Slíwa Martyna 
Published: October 2016

Purpose
This paper aims to suggest a shift in thinking about how to improve gender inclusion in organizations, as well as offering a number of practical action points.

Design/methodology/approach
This paper takes a perspective based on the authors’ own ongoing research, as well as synthesis of existing insights into gender inclusion in organizations.

Findings
To retain top talent and improve organizational climate, the authors need to re-think how the authors measure the success of organizational inclusion policies. Specifically, the paper suggests moving from numbers and targets to looking at the quality of gender inclusion in the workplace. The paper explains why this shift in thinking is important and how to approach it in practice.

Practical implications
The paper provides strategic insights into and practical thinking about ways in which progressive organizations can continue to improve gender equality.

Originality/value
The paper makes a provocative call for a change of perspective on gender inclusion in organizations based on cutting-edge research and puts forward action points in an accessible format.
Hospital-based violence intervention programs targeting adult populations: an Eastern Association for the Surgery of Trauma evidence-based review
Authors: Affinati Steven , Patton Desmond , Hansen Luke , Ranney Megan , Christmas A Britton , Violano Pina , Sodhi Aparna , Robinson Bryce , Crandall Marie ,   from the Eastern Association for the Surgery of Trauma Injury Control and Violence Prevention Section and Guidelines Section
Published: October 2016

BackgroundViolent injury and reinjury take a devastating toll on distressed communities. Many trauma centers have created hospital-based violent injury prevention programs (HVIP) to address psychosocial, educational, and mental health needs of injured patients that may contribute to reinjury.ObjectivesTo evaluate the overall effectiveness of HVIPs for violent injury prevention. We performed an evidence-based review to answer the following population, intervention, comparator, outcomes (PICO) question: Are HVIPs attending to adult patients (age 18+) treated for intentional injury more effective than the usual care at preventing: intentional violent reinjury and/or death; arrest and/or incarceration; substance abuse and/or mental issues; job and/or school attainment?Data sourcesPubMed, Web of Science, Google Scholar, and the Cochrane Library were queried for salient articles by a professional librarian on two separate occasions, and related articles were identified from references.Study eligibility criteria, participants, interventionsEligible studies examined adult patients treated for intentional injury in a hospital-based violence prevention program compared to a control group.Study appraisal and synthesis methodsWe used the Grading of Recommendations Assessment, Development, and Evaluation methodology to assess the breadth and quality of the evidence.Results71 articles were identified. After discarding duplicates, reviews, and those articles that did not address our PICO questions, we ultimately reviewed 10 articles. We found insufficient evidence to recommend adult-focused HVIP interventions.LimitationsThere was a relative paucity of data, and available studies were limited by self-selection bias and small sample sizes.ConclusionsWe make no recommendation with respect to adult-focused HVIP interventions.
The energy separation effect based on the disk resonance multichannel MIM waveguide
Authors: Wang Liu , Zeng Ya-Ping , Wang Zhi-Yong , Xia Xiong-Ping , Liang Qiu-Qun 
Published: October 2016

In this paper, a multichannel metal–insulator–metal (MIM) waveguide structure based on a disk resonator is proposed. The transmission characteristics of visible and near-infrared light in the waveguide are investigated by using the finite-difference time-domain (FDTD) method. The results show that the structure has typical band-pass filter function due to the wave resonance in the nanodisk. The energy of the second-order resonance wavelength of the disk can transmit through each output port averagely, which is realized by the energy separation function of the electromagnetic wave. Moreover, the wavelength will transmit through the output port in redshift as the radius and/or the refractive index of the disk are increased. The transmissivity is sharply reduced with the increase of the coupling thickness between the disk and the output port waveguide.
Bactericidal Efficiency of Silver Nanoparticles Synthesized from Annona squamosa
Authors: Jayavardhanan R. , Nanda Anima 
Published: October 2016

Nanotechnology is described as an emerging technology that not only holds promise for society, but also is capable of providing novel approaches to overcome our common problems. The present study focused on the synthesis of silver nanoparticles using the metabolites of Annona squamosa seeds. The biological reduction procedure proposed in this method was considered as better one compared to chemical mediated reduction methods. The advantages include nontoxic to the environment, less energy consuming and highly suitable for further biological applications. The seeds were separated from the fruit pulp, grinded into powder and dissolved in distilled water. The suspension was used as reducing agent and treated with silver nitrate at the concentration of 1[Formula: see text]mM. The reduction reaction was continuously monitored by UV-visible photo spectrometer. Further the samples were subjected to AFM, SEM and XRD analysis for the confirmation of their size, structure, agglomerations and the arrangements of crystals. Finally the antibacterial properties of nanoparticles were tested against clinically important pathogenic microorganisms using disc diffusion method and compared with the activities of standard antibiotics. The combinational effects of nanoparticles with commercial antibiotics also were tested by the same method.
Cracking the Code of Resistance across Multiple Lines of ALK Inhibitor Therapy in Lung Cancer
Authors: Qiao Huan , Lovly Christine M. 
Published: October 2016

Abstract
Summary: In the setting of recent exciting clinical results and numerous ongoing trials, Gainor and colleagues explored mechanisms of acquired resistance to first- and second-generation ALK inhibitors in ALK-rearranged non–small cell lung cancer and found that an increased frequency and distinct spectrums of resistance mutations emerged with the more potent second-generation inhibitors. Their findings have important and immediate clinical implications as the resistance mutations detected impart differential sensitivities to available ALK inhibitors, thereby highlighting the need for sequential biopsies with molecular testing to determine the most effective treatment strategy upon disease progression. Cancer Discov; 6(10); 1084–6. ©2016 AACR.
See related article by Gainor et al., p. 1118.
Accurate Medicine: Indirect Targeting of NPM1-Mutated AML
Authors: Hourigan Christopher S. , Aplan Peter D. 
Published: October 2016

Abstract
Summary: Acute myeloid leukemia (AML) is now recognized to be an imprecise term that refers to a range of myeloid malignancies that have different genetical etiologies, clinical characteristics, and therapeutic sensitivities. Targeting the MLL1 and DOT1L histone modification complexes, both alone and in combination, showed activity against AML driven by a mutant NPM1 protein in several preclinical models and may represent a new treatment direction for this devastating disease. Cancer Discov; 6(10); 1087–9. ©2016 AACR.
See related article by Kühn and colleagues p. 1166.
On Blaps Fabricius, 1775 (Coleoptera: Tenebrionidae) from Western Kazakhstan with description of a new species from Tyuleniy Archipelago (Caspian Sea)
Authors: CHIGRAY IVAN A. , ABDURAKHMANOV GAYIRBEG M. , NABOZHENKO MAXIM , SHAPOVALOV ANDREY M. 
Published: October 2016

A new species of darkling beetles Blaps caspica sp. n. from Western Kazakhstan Kulaly Island (Tyuleniy Archipelago, Caspian Sea) is described. This new taxon belongs to the 6th group of the 2nd section according to Seidlitz’s classification and is most similar to Blaps kadyrbekovi G. Medvedev, 2004, B. lethifera Marsham, 1802 and B. parvicollis Zoubkoff, 1829. Blaps caspica sp. n. differs from B. kadyrbekovi by the presence of a hair tuft between male abdominal ventrites 1 and 2, from B. parvicollis by having narrow acute short spurs on the mesotibiae, the structure of the gastral spicula, ovipositor and female genital tubes, from B. lethifera by the slender elliptic body, punctated (not granulated) epipleura and the structure of the female genital tubes. Images, an identification key and local distribution are given for ten Western Kazakhstan species of the genus Blaps Fabricius, 1775.
Regional Variability of Rain Clouds in the Amazon Basin as Seen by a Network of Weather Radars
Authors: Saraiva I. , Silva Dias M. A. F. , Morales C. A. R. , Saraiva J. M. B. 
Published: October 2016

AbstractA new dataset based on 5 yr of operational meteorological weather radars from the Amazon Protection System has enabled new knowledge in relation to rainfall in the Amazon basin. The rainy features are analyzed for 10 different regions in terms of the annual and diurnal cycles of radar reflectivity, as well as the vertical distribution, in addition to lightning data. Similarities between the annual and diurnal cycles are found in the northwestern and western, southwestern and southern, and northeastern and northern Amazon. Nocturnal peaks are found in stratiform fraction in the southern, southwestern, western, northwestern, northern, central western, and coastal regions. The convective fractions in the western, northwestern, northern, and central eastern regions also show nocturnal peaks. The radar reflectivity vertical distributions analysis indicates that in the northern coast close to Belém, heavy rainfall with deep convective systems is observed throughout the year, while heavy rainfall in the central Amazon close to Manaus, Tefé, and Santarém occurs in the dry season. More oceanic-like clouds are also observed there and in other locations on the northern coast like Macapá, where the frequency of lightning is quite low. São Gabriel da Cachoeira, located in the northwest portion of the Amazon basin, has a regime with rainfall in all seasons with a slight decrease from August to October when the systems become more convective and have more lightning.
Handling missing rows in multi-omics data integration: multiple imputation in multiple factor analysis framework
Authors: Voillet Valentin , Besse Philippe , Liaubet Laurence , San Cristobal Magali , González Ignacio 
Published: October 2016

AbstractBackgroundIn omics data integration studies, it is common, for a variety of reasons, for some individuals to not be present in all data tables. Missing row values are challenging to deal with because most statistical methods cannot be directly applied to incomplete datasets. To overcome this issue, we propose a multiple imputation (MI) approach in a multivariate framework. In this study, we focus on multiple factor analysis (MFA) as a tool to compare and integrate multiple layers of information. MI involves filling the missing rows with plausible values, resulting inMcompleted datasets. MFA is then applied to each completed dataset to produceMdifferent configurations (the matrices of coordinates of individuals). Finally, theMconfigurations are combined to yield a single consensus solution.ResultsWe assessed the performance of our method, named MI-MFA, on two real omics datasets. Incomplete artificial datasets with different patterns of missingness were created from these data. The MI-MFA results were compared with two other approaches i.e., regularized iterative MFA (RI-MFA) and mean variable imputation (MVI-MFA). For each configuration resulting from these three strategies, the suitability of the solution was determined against the true MFA configuration obtained from the original data and a comprehensive graphical comparison showing how the MI-, RI- or MVI-MFA configurations diverge from the true configuration was produced. Two approaches i.e., confidence ellipses and convex hulls, to visualize and assess the uncertainty due to missing values were also described. We showed how the areas of ellipses and convex hulls increased with the number of missing individuals. A free and easy-to-use code was proposed to implement the MI-MFA method in the R statistical environment.ConclusionsWe believe that MI-MFA provides a useful and attractive method for estimating the coordinates of individuals on the first MFA components despite missing rows. MI-MFA configurations were close to the true configuration even when many individuals were missing in several data tables. This method takes into account the uncertainty of MI-MFA configurations induced by the missing rows, thereby allowing the reliability of the results to be evaluated.
The Foundation Programme in psychiatry: a qualitative study into the effects of a foundation placement
Authors: Boyle Ann , Davies Sophie , Dogra Nisha , Perry Jennifer , Fosker Hannah 
Published: October 2016

Aims and methodThere is a drive to increase the number of psychiatry foundation placements to ensure that training keeps up with the changing health and social care landscape. This qualitative study aimed to explore, by interview, the experiences of 17 doctors who have completed a foundation placement in psychiatry.ResultsThe study highlights the benefits of foundation psychiatry placements and some of their positive and negative aspects.Clinical implicationsThose developing foundation placements will need to ensure they are of high quality.
Digitally enabled patients, professionals and providers: making the case for an electronic health record in mental health services
Authors: Richardson Jonathan , McDonald Joe 
Published: October 2016

SummaryThe move to a digital health service may improve some components of health systems: information, communication and documentation of care. This article gives a brief definition and history of what is meant by an electronic health record (EHR). There is some evidence of benefits in a number of areas, including legibility, accuracy and the secondary use of information, but there is a need for further research, which may need to use different methodologies to analyse the impact an EHR has on patients, professionals and providers.
The application of Rasch measurement theory to psychiatric clinical outcomes research
Authors: Barbic Skye P. , Cano Stefan J. 
Published: October 2016

SummaryThis commentary argues the importance of robust, meaningful assessment of clinical and functional outcomes in psychiatry. Outcome assessments should be fit for the purpose of measuring relevant concepts of interest in specific clinical settings. As well, the measurement model selected to develop and test assessments can be critical for guiding care. Three types of measurement models are presented: classical test theory, item response theory, and Rasch measurement theory. To optimise current diagnostic and treatment practices in psychiatry, careful consideration of these models is warranted.
Evolutionary psychiatry: a new College special interest group
Authors: Abed Riadh , John-Smith Paul St 
Published: October 2016

SummaryEvolutionary science remains an overlooked area in psychiatry and medicine. The newly established Royal College of Psychiatrists' Evolutionary Psychiatry Special Interest Group aims to reverse this trend by raising the profile of evolutionary thinking among College members and others further afield. Here we provide a brief outline of the importance of the evolutionary approach to both the theory and practice of psychiatry and for future research.
Premature Ovarian Insufficiency: New Perspectives on Genetic Cause and Phenotypic Spectrum
Authors: Tucker Elena J. , Grover Sonia R. , Bachelot Anne , Touraine Philippe , Sinclair Andrew H. 
Published: October 2016

AbstractPremature ovarian insufficiency (POI) is one form of female infertility, defined by loss of ovarian activity before the age of 40 and characterized by amenorrhea (primary or secondary) with raised gonadotropins and low estradiol. POI affects up to one in 100 females, including one in 1000 before the age of 30. Substantial evidence suggests a genetic basis for POI; however, the majority of cases remain unexplained, indicating that genes likely to be associated with this condition are yet to be discovered. This review discusses the current knowledge of the genetic basis of POI. We highlight genes typically known to cause syndromic POI that can be responsible for isolated POI. The role of mouse models in understanding POI pathogenesis is discussed, and a thorough list of candidate POI genes is provided. Identifying a genetic basis for POI has multiple advantages, such as enabling the identification of presymptomatic family members who can be offered counseling and cryopreservation of eggs before depletion, enabling personalized treatment based on the cause of an individual's condition, and providing better understanding of disease mechanisms that ultimately aid the development of improved treatments.
Career Advancement: Meeting the Challenges Confronting the Next Generation of Endocrinologists and Endocrine Researchers
Authors: Santen Richard J. , Joham Anju , Fishbein Lauren , Vella Kristen R. , Ebeling Peter R. , Gibson-Helm Melanie , Teede Helena 
Published: October 2016

Context:
Challenges and opportunities face the next generation (Next-Gen) of endocrine researchers and clinicians, the lifeblood of the field of endocrinology for the future. A symposium jointly sponsored by The Endocrine Society and the Endocrine Society of Australia was convened to discuss approaches to addressing the present and future Next-Gen needs.

Evidence Acquisition:
Data collection by literature review, assessment of previously completed questionnaires, commissioning of a new questionnaire, and summarization of symposium discussions were studied.

Evidence Synthesis:
Next-Gen endocrine researchers face diminishing grant funding in inflation-adjusted terms. The average age of individuals being awarded their first independent investigator funding has increased to age 45 years. For clinicians, a workforce gap exists between endocrinologists needed and those currently trained. Clinicians in practice are increasingly becoming employees of integrated hospital systems, resulting in greater time spent on nonclinical issues. Workforce data and published reviews identify challenges specifically related to early career women in endocrinology.

Strategies to Address Issues:
Recommendations encompassed the areas of grant support for research, mentoring, education, templates for career development, specific programs for Next-Gen members by senior colleagues as outlined in the text, networking, team science, and life/work integration. Endocrine societies focusing on Next-Gen members provide a powerful mechanism to support these critical areas.

Conclusions:
A concerted effort to empower, train, and support the next generation of clinical endocrinologists and endocrine researchers is necessary to ensure the viability and vibrancy of our discipline and to optimize our contributions to improving health outcomes. Collaborative engagement of endocrine societies globally will be necessary to support our next generation moving forward.
“We Then Went to England”: Shawnee Storytelling and the Atlantic World
Authors: Lakomäki Sami 
Published: October 2016

Abstract
Between 1795 and 1808 several Shawnee orators recounted to British and US officials a story about a Shawnee voyage to England. These narratives push scholars to reconsider the Atlantic world paradigm from an Indigenous perspective. They reveal Native constructions of space and historicity that cannot be easily integrated into the standard frameworks of Atlantic history. Instead of an ocean that united four continents into a single “Atlantic world,” the Shawnee storytellers imagined a kčikami, a dangerous borderland separating radically different cultural, spiritual, and racial realms. Such Native understandings of the sea are critical for indigenizing past landscapes often framed in Eurocentric terms. Moreover, the Shawnee narratives highlight the complex roles of storytelling in Native-newcomer relations and Shawnee intranational debates during a critical period when growing colonial power rapidly eroded the “middle ground” across the lower Great Lakes and political disputes factionalized the Shawnees, putting new pressures on how people constructed and forgot the past.
Wabanaki Homeland and Mobility: Concepts of Home in Nineteenth-Century Maine
Authors: Pawling Micah 
Published: October 2016

AbstractIn the nineteenth century the Penobscot and Passamaquoddy Indian nations preserved considerable mobility across their traditional homeland. This case study uses petitions and other primary sources to show that many Native families maintained connections to places that their ancestors once inhabited. While the Penobscot reservation consisted of the river islands above the head of tide, families continued to return to Penobscot Bay to harvest marine resources. Other kin groups revisited old sites on the Kennebec River. Non-Native town officials wanted to send the Indians home but were blind to the fact that the Wabanaki peoples already understood themselves to be home. For the Passamaquoddy at Pleasant Point (Sipayik), resources such as birch bark and firewood were scarce, prompting them to harvest wood on private property for survival. Tension between private property and traditional homeland remained unresolved as Wabanaki peoples persevered in their partially colonized homeland.
Collecting clinical data in primary ciliary dyskinesia- challenges and opportunities
Authors: Amirav Israel , Roduta Roberts Mary , Mussaffi Huda , Mandelberg Avigdor , Roth Yehudah , Abitbul Revital , Luder Anthony , Blau Hannah , Alkrinawi Soliman , Aviram Micha , Ben-Ami Marta , Rotschild Moshe , Bentur Lea , Shoseyov David , Cohen-Cymberknoh Malena , Kerem Eitan , Avital Avraham , Springer Chaim , Hevroni Avigdor , Dabbah Husein , Elizur Arnon , Picard Elie , Goldberg Shmuel , Rivlin Joseph , Livnat Galit , Lavie Moran , Alias Nael , Soferman Ruth , Olbrich Heike , Raidt Johanna , Wallmeier Julia , Werner Claudius , Loges Niki T. , Omran Heymut 
Published: October 2016

Rationale: Primary ciliary dyskinesia (PCD) is under diagnosed and underestimated. Most clinical research has used some form of questionnaires to capture data but none has been critically evaluated particularly with respect to its end-user feasibility and utility. Objective: To critically appraise a clinical data collection questionnaire for PCD used in a large national PCD consortium in order to apply conclusions in future PCD research. Methods: We describe the development, validation and revision process of a clinical questionnaire for PCD and its evaluation during a national clinical PCD study with respect to data collection and analysis, initial completion rates and user feedback. Results: 14 centers participating in the consortium successfully completed the revised version of the questionnaire for 173 patients with various completion rates for various items. While content and internal consistency analysis demonstrated validity, there were methodological deficiencies impacting completion rates and end-user utility. These deficiencies were addressed resulting in a more valid questionnaire. Conclusions: Our experience may be useful for future clinical research in PCD. Based on the feedback collected on the questionnaire through analysis of completion rates, judgmental analysis of the content, and feedback from experts and end users, we suggest a practicable framework for development of similar tools for various future PCD research.