bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Fat Grafts for Stabilizing Microvascular Pedicle Geometry in Head and Neck Reconstruction
Authors: Yagi Shunjiro , Suyama Yoshiko , Fukuoka Kohei , Morita Maki , Kambe Miki , Toriyama Kazuhiro , Kamei Yuzuru 
Published: November 2017

Background Even after careful microanastomosis, microsurgeons sometimes encounter unexpected twisting, kinking, and destabilizing mechanical forces. In these cases, a small fat graft is a useful technique for stabilizing the pedicle geometry in free flap transfer. However, few reports have provided the details with an analysis of fat graft use. The use of fat grafts for free flap transfer in head and neck reconstruction was reviewed.
Materials and Methods This was a retrospective review of 157 patients (116 men, 41 women; average ± SD age: 64 ± 13.1 years) who had undergone head and neck reconstruction with free flap transfer between 2010 and 2016. We used a fat graft to stabilize pedicle geometry to prevent kinking and other problems. Postoperative thrombosis formation and the use of a fat graft at the pedicle depending on recipient vessel selection and reconstructed site were examined.
Results In 23 patients (14.6%), fat grafting was performed to correct pedicle geometry. A fat graft was used at the arterial anastomosis in 13 patients and at the venous anastomosis in 10. There were no significant differences in postoperative thrombosis formation depending on the use of a fat graft. However, fat grafts were more likely to be performed with the superior thyroid artery as a recipient artery and in tongue and/or oral cavity reconstruction.
Conclusion A fat graft is a reliable and easy procedure to correct pedicle geometry. However, reconstructive surgeons should consider the use of a fat graft based on the selection of the recipient vessels and the recipient site.
The Independent Contribution of Uterine Blood Flow to Birth Weight and Body Composition in Smoking Mothers
Authors: Bernstein Ira , Skelly Joan , Heil Sarah , Higgins Stephen , Cooper Kylie 
Published: November 2017

Objective This study aims to evaluate the relationship of maternal smoking to uterine artery hemodynamics and examine independent contributions to birth weight and fetal body composition.
Study Design Women were enrolled in a prospective randomized controlled study targeting smoking abstinence. Uterine artery Doppler ultrasound was performed and volumetric blood flow was calculated. Third trimester ultrasound estimates of fetal body composition were performed and birth weight was recorded.
Results Uterine artery volumetric flow and resistance index (RI) were significantly correlated with birth weight adjusted for gestational age (R = 0.35, p = 0.002; R = − 0.27, p = 0.02). Volumetric flow was significantly associated with fetal fat mass (R = 0.30, p = 0.018). Smoking status did not have significant effects on lean body mass (t [61] = 0.60, p = 0.55), fat mass (t [61] = 1.67, p = 0.10), or volumetric flow (t = 0.86, df = 87, p = 0.39). Stepwise regression identified volumetric flow (β = 0.81, 95% confidence interval [CI]: 0.35–1.27, p < 0.001), maternal prepregnancy body mass index (β = 16.04, 95% CI: 2.57–29.50, p = 0.02), and fetal sex (β = 346.28, 95% CI: −532.64 to 159.91, p < 0.001, where male = 0 and female = 1) as independent contributors to birth weight adjusted for gestational age.
Conclusion No direct relationship of smoking to uterine artery hemodynamics was demonstrated. Volumetric flow was an independent contributor to birth weight and was associated with fetal fat deposition, while smoking was not independently associated with either outcome.
Epidemiological Features of Patients with Subdural Hygroma in a Prospective Case Series
Authors: Hamamoto Filho Pedro , Pereira Tamara , Zanini Marco 
Published: November 2017

AbstractSubdural hygroma is an accumulation of a cerebrospinal fluid-like fluid in the subdural space. It is a common epiphenomenon after a traumatic brain injury (TBI), but it may also occur after brain surgeries. A total of 17 patients in a prospective case series with subdural hygromas were analyzed. A male predominance (82.4%) was found. The mean age was 58.6 years. Traumatic brain injury was the main mechanism (76.5%); however, other mechanisms, such as post-craniotomy (17.6%), post-chronic subdural hematoma drainage (5.9%), and post-ventricle shunt (5.9%), were also observed. Incidental findings were diagnosed in 11.8% of the cases (mainly in elderly patients). Four patients required subdural shunt (23.5%)—all of them had TBI. Small subdural effusions were present in 35.5% of the cases. The mean time from admission to diagnosis was 6.1 days. The majority of the cases must have involved lesions of the dura–arachnoid interface since TBIs were the main causes of hygroma. The findings of incidental hygroma in elderly patients and its development after a ventricle shunt suggest that brain atrophy also plays a significant role in subdural hygroma formation.
The Fifty Most Cited Articles on Extra-articular Hip Pathology
Authors: Swindell Hasani , Mayeux Sophie , Noticewala Manish , Ahmad Christopher , Lynch T. , Trofa David 
Published: November 2017

AbstractThe number of times an article has been cited is thought to correspond with its level of academic influence. Within the orthopaedic literature, several citation analyses have been performed, including a recent investigation on the most commonly cited articles on femoroacetabular impingement (FAI); however, no study has determined the most cited investigations on extracapsular hip pathologies, including osteitis pubis, athletic pubalgia, and muscle strains. Such pathologies constitute a significant proportion of lower extremity injuries among athletes. The purpose of this study was to determine the 50 most cited investigations on extra-articular hip injuries by performing a systematic query of the Institute for Scientific Information (ISI) Web of Science (Thomson Reuters, Philadelphia, PA). The following characteristics were determined for each article: number of citations, citation density, journal and publication year, country of origin, language, article type, article subtype, and level of evidence. The number of citations ranged from 46 to 202 (mean 84.4), and the citation densities ranged from 1.7 to 28.4 citations per year (mean: 7.9). Sixty-eight percent of the selected articles involved hamstring strains. The majority of articles were published in the American Journal of Sports Medicine (58%), followed by the Journal of Orthopaedic and Sports Physical Therapy (12%). Most articles were published during the 2000s, originated from the United States, and 100% were written in English. Eighty percent were clinical studies; the majority of which had Level IV evidence. This collection of academic investigations on athletic extra-articular hip injuries can aid in the establishment of a reading curriculum for trainees participating in orthopaedic training programs.
Relation of Carotid Artery Plaque to Coronary Heart Disease and Stroke in Chinese Patients: Does Hyperglycemia Status Matter?
Authors: Zhou Huanhuan , Wang Xiaoyun , Zhu Junya , Fish Anne , Kong Weimin , Li Fan , Liu Lin , Yuan Xiaodan , Gao Xin , Lou Qingqing 
Published: November 2017

Abstract
Objective To examine the association of carotid artery plaque with the incident coronary heart disease and stroke events in Chinese patients and explore whether the association differs between patients with and without hyperglycemia.
Methods We evaluated plaque, and blood pressure, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, fasting serum insulin, fasting plasma glucose, 2 h postprandial glucose and Homeostasis model assessment of insulin resistance in 253 Chinese patients. T-test and X2 test were used to compare the clinical characteristics and Binary logistic regression was applied to analyze the association of coronary heart disease and stroke between patients with and without hyperglycemia.
Results Among 253 patients, 162 patients had hyperglycemia (i. e., diabetes, impaired glucose regulation and stress induced hyperglycemia) and 155 (61.3%) patients had plaque. Fasting plasma glucose, 2 h postprandial glucose and Homeostasis model assessment of insulin resistance, triglycerides, plaque were significantly higher in the hyperglycemia group than non-hyperglycemia. The incident coronary heart disease and stroke events in patients with plaque were 2.254 (95%CI,1.203–4.224) and 2.437 (95%CI,1.042–5.701) times higher than those without plaque, respectively. Among hyperglycemia subgroup, plaque was an independent risk factor for coronary heart disease (OR,3.075,95%CI,1.353–6.992) and stroke (OR,3.571,95%CI,1.460–8.737). The slopes (associations between coronary heart disease/stroke and plaque) were steeper in the hyperglycemia group than those in the non-hyperglycemia group (coronary heart disease OR,3.075 vs. 2.614; stroke OR,3.571 vs. 3.307).
Conclusions The incident coronary heart disease and stroke events in patients with plaque were higher than those without plaque, and this difference was more pronounced for patients with hyperglycemia vs. those without hyperglycemia.
Organspende bei Patienten nach nicht traumatischem außerklinischem Herzstillstand
Authors: Christ Martin , von Auenmüller Katharina , Brand Michael , Gessner Verena , Grett Martin , Zalloum Nedall , Dierschke Wolfgang , Trappe Hans-Joachim 
Published: November 2017

Zusammenfassung
Einleitung Der außerklinische Herzstillstand (out-of-hospital cardiac-arrest = OHCA) ist in der Kardiologie eine der häufigsten Todesursachen. Obwohl jedoch schon frühere Studien zeigen konnten, dass die Möglichkeit besteht, Organe auch von reanimierten Spendern zu transplantieren, bleiben Organspenden nach OHCA selten. Diese Studie wurde daher initiiert, um den Prozentsatz von Organspenden unter Patienten nach außerklinischem Herzstillstand in einem deutschen Universitätsklinikum zu ermitteln.
Material und Methode Es wurden die Daten aller Patienten nach außerklinischer Reanimation ermittelt, die zwischen dem 1. Januar 2008 und dem 31. Mai 2017 in unser Krankenhaus eingeliefert wurden.
Ergebnisse Insgesamt wurden 385 Patienten nach außerklinischem Herzstillstand in unsere Klinik eingeliefert. 126 Patienten (32,8 %) überlebten nach OHCA bis zur Krankenhausentlassung, 259 (67,2 %) starben innerklinisch, darunter 7 Patienten (1,8 %) mit nachgewiesenem Hirntod. 5 Patienten nach OHCA (1,5 %) spendeten ihre Organe und insgesamt konnten 14 Organe erfolgreich transplantiert werden.
Diskussion Die Organspende nach außerklinischem Herzstillstand ist selten. Die häufigere Durchführung einer Hirntoddiagnostik ist erstrebenswert, erhalten momentan doch noch nicht einmal all diejenigen Patienten eine Hirntoddiagnostik, bei denen in der Computertomografie eine nachgewiesene Hirnschädigung besteht.
Eine ICF-Checkliste als Instrument zur Beurteilung von Inklusion bei alten Menschen mit geistiger Behinderung – Pilotstudie zur psychometrischen Güte
Authors: Queri Silvia , Eggart Michael , Wendel Maren , Peter Ulrike 
Published: November 2017

Zusammenfassung
Hintergrund Zur Beurteilung, inwieweit Inklusionsbemühungen für alte geistig Behinderte erfolgreich sind, wurde ein Messinstrument entwickelt. Dazu wurden aus der ICF das Teilhabekonzept sowie die Umweltfaktoren verwendet. So können Teilhabefortschritte evaluiert und Umweltfaktoren identifiziert werden, die Barrieren für Teilhabe und Inklusion darstellen.
Methodik 138 Items der ICF wurden mit dem VINELAND-II verlinkt. Diese ICF-Checkliste wurde zu t1 retrospektiv und zu t2 aktuell durch Proxy-Befragungen (67 Mitarbeiter) ausgefüllt. 50 geistig Behinderte (F70/F71), durchschnittlich 68 Jahre alt, wurden zu ihrer subjektiv wahrgenommen Lebensqualität (IEM/LZF) direkt befragt. Zum Nachweis der psychometrischen Güte wurde die Inhaltsvalidität anhand von Faktorenanalysen geprüft. Die Kriteriumsvalidität wurde korrelativ mit den Kriterien wahrgenommener Lebensqualität (IEM/LZF) sowie notwendiger Hilfebedarf (SIS) und dem Ausmaß an Verhaltensauffälligkeiten (VFE) geprüft, die letzten beiden via Proxy-Befragungen erhoben. Die quantitativen Analysen wurden durch eine qualitative Inhaltsanalyse validiert.
Ergebnisse Variablencluster zeigen eine inhaltslogische Struktur. Die Checkliste ist reliabel und valide. Es zeigen sich alterskorrelierte Veränderungen und die qualitative Analyse korrespondiert mit den Ergebnissen.
Schlussfolgerung Die ICF-Checkliste kann für die anstehende Versorgungsplanung dieser Personengruppe und als Evaluationsinstrument eingesetzt werden.
Osmosensing by the bacterial PhoQ/PhoP two-component system
Authors: Yuan Jing , Jin Fan , Glatter Timo , Sourjik Victor 
Published: November 2017

Significance
Whether residing in or invading the host, enterobacteria have to deal with host-related stress conditions. These stress factors also serve as sensory cues, informing bacteria that they are present inside the host. Here, we report that the PhoQ/PhoP two-component system, which was known to sense several host-related environmental changes, responds to osmotic upshift, another key stimulus associated with the host. This sensing is proposed to rely on a mechanism that detects changes in the physical properties of the membrane. Thus, a single enterobacterial kinase, PhoQ, senses a major part of host-associated stimuli. The PhoQ-mediated osmosensing increases bacterial fitness under hyperosmotic conditions found inside the host, and it is likely to play an important role in the regulation of virulence.
A comparison of diminutive expressions in English and Slovene
as exemplified by Roald Dahl’s Matilda
Authors: Sicherl Eva 
Published: November 2017

Abstract
The article presents and compares ways of expressing diminution in English and
Slovene nouns, verbs and adjectives with the aim of testing a hypothesis
suggesting that Slovene uses diminutive forms more frequently than English.
Depending on language typology, diminutiveness can be realized predominantly
word-formationally or predominantly analytically. The hypothesis is tested
against an analysis of diminutive forms used in Dahl’s Matilda
and its Slovene translation, showing that Slovene indeed prefers to use
diminutives more frequently than English. A tendency can be established for
Slovene to form diminutives by word-formational means in the categories of noun
and verb. In verbs, English tends towards neutrality of expression. Frequent use
of multiple diminutiveness and the ability of analytic and synthetic diminutive
forms to be freely interchangeable in Slovene testify to the strong presence of
diminutive forms in the language system.
Shallow features as indicators of English–German contrasts in lexical cohesion
Authors: Kunz Kerstin , Lapshinova-Koltunski Ekaterina , Martínez Martínez José Manuel , Menzel Katrin , Steiner Erich 
Published: November 2017

Abstract
This paper contrasts lexical cohesion between English and German spoken and
written registers, reporting findings from a quantitative lexical analysis.
After an overview of research aims and motivations we formulate hypotheses on
distributions of shallow features as indicators of lexical cohesion across
languages and modes and with respect to register ranking and variation. The
shallow features analysed are: highly frequent words in texts, lexical density,
standardized type-token-ratio, top-frequent content words of the language within
individual registers and texts, and several types of Latinate words. Descriptive
analyses of the corpus are then presented and statistically validated with the
help of univariate and multivariate analyses. The results are interpreted
relative to our hypotheses and related to the following properties of texts in
terms of lexical cohesion: semantic variability, cohesive strength, number and
length of nominal chains, degree of specification of lexis, and degree of
variation along all of these properties.
Blood Cockle Shells Waste as Renewable Source for the Production of Biogenic CaCO3 and Its Characterisation
Authors: Asmi D , Zulfia A 
Published: November 2017

Abstract
The prowess to reuse and recycle of blood cockle shells for raw material in bio-ceramics applications is an attractive component of integrated waste management program. In this paper an attempt is made to introduce a simple process to manufacture biogenic CaCO3 powder from blood cockle shells waste. The biogenic CaCO3 powder was produced from rinsing of blood cockle shells waste using deionised water and oxalic acid for cleaning the dirt and stain on the shells, then drying and grinding followed by heat treatment at 500 and 800 °C for 5 h. The powder obtained was characterised by XRF, DTA/TG, SEM, FTIR, and XRD analysis. The amount of 97.1 % CaO was obtained from XRF result. The thermal decomposition of CaCO3 become CaO due to mass loss was observed in the TG curve. The SEM result shows the needle-like aragonite morphology of blood cockle shells powder transformed to cubic-like calcite after heat treated at 500 °C. These results were consistent with FTIR and XRD results.
Complete Integrability of the Parahoric Hitchin System
Authors: Baraglia David , Kamgarpour Masoud , Varma Rohith 
Published: November 2017

AbstractLet $\mathcal {G}$ be a parahoric group scheme over a complex projective curve X of genus greater than one. Let $\mathrm {Bun}_{\mathcal {G}}$ denote the moduli stack of $\mathcal {G}$-torsors on X. We prove several results concerning the Hitchin map on $T^{\ast }\!\mathrm {Bun}_{\mathcal {G}}$. We first show that the parahoric analogue of the global nilpotent cone is isotropic and use this to prove that $\mathrm {Bun}_{\mathcal {G}}$ is “very good” in the sense of Beilinson–Drinfeld. We then prove that the parahoric Hitchin map is a Poisson map whose generic fibres are abelian varieties. Together, these results imply that the parahoric Hitchin map is a completely integrable system.
Luminous quasars do not live in the most overdense regions of galaxies at z ∼ 4
Authors: Uchiyama Hisakazu , Toshikawa Jun , Kashikawa Nobunari , Overzier Roderik , Chiang Yi-Kuan , Marinello Murilo , Tanaka Masayuki , Niino Yuu , Ishikawa Shogo , Onoue Masafusa , Ichikawa Kohei , Akiyama Masayuki , Coupon Jean , Harikane Yuichi , Imanishi Masatoshi , Kodama Tadayuki , Komiyama Yutaka , Lee Chien-Hsiu , Lin Yen-Ting , Miyazaki Satoshi , Nagao Tohru , Nishizawa Atsushi J , Ono Yoshiaki , Ouchi Masami , Wang Shiang-Yu 
Published: November 2017

Abstract
We present the cross-correlation between 151 luminous quasars (MUV &lt; −26) and 179 protocluster candidates at z ∼ 3.8, extracted from the Wide imaging survey (∼121 deg2) performed as part of the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP). We find that only two out of 151 quasars reside in regions that are more overdense compared to the average field at &gt;4 σ. The distributions of the distances between quasars and the nearest protoclusters and the significance of the overdensity at the positions of quasars are statistically identical to those found for g-dropout galaxies, suggesting that quasars tend to reside in almost the same environment as star-forming galaxies at this redshift. Using stacking analysis, we find that the average density of g-dropout galaxies around quasars is slightly higher than that around g-dropout galaxies on 1.0–2.5 pMpc scales, while at &lt;0.5 pMpc that around quasars tends to be lower. We also find that quasars with higher UV luminosity or with more massive black holes tend to avoid the most overdense regions, and that the quasar near-zone sizes are anti-correlated with overdensity. These findings are consistent with a scenario in which luminous quasars at z ∼ 4 reside in structures that are less massive than those expected for the progenitors of today’s rich clusters of galaxies, and possibly that luminous quasars may be suppressing star formation in their close vicinity.
A Pilot Study of Responses to Suctioning Among Neonates on Bubble Nasal Continuous Positive Airway Pressure
Authors: Sweet Michele , Armbruster Debra , Bainbridge Erin , Reiner Brianna , Tan Alai , Chipps Esther 
Published: November 2017

Background:
Maintenance of a patent airway while the neonate is on nasal continuous positive airway pressure (nasal CPAP) requires vigilant monitoring and oral/nasopharyngeal suctioning. Currently, no evidence-based guidelines for safe suctioning in neonates while on bubble nasal CPAP have been published.

Purpose:
(1) To characterize the clinical and behavioral responses of neonates on bubble nasal CPAP in a level III neonatal intensive care unit following routine oral and nasopharyngeal suctioning.

Methods:
This pilot study has a 1-sample within-subject repeated-measures design in which neonates (N = 16) served as their own control. Data on a neonate's physiological and behavior measures (heart rate, respiratory rate, oxygen saturation [Sao
2], and Premature Infant Pain Profile [PIPP] score) were collected before, during, and after the completion of suctioning sequence.

Finding/Results:
A total of 16 neonates with a mean gestational age of 29.76 weeks and an average day of life of 3.4 were enrolled. The infant's heart rates did not differ significantly (P = .51) across the suctioning sequence. There were no statistical significant changes in the average respiratory rate across the suctioning sequences (P = .79). Sao
2 demonstrated a drop between baseline and after each suctioning (P < .001). The PIPP score demonstrated a precipitous increase throughout the procedure (P < .001). On average, it took 9.5 seconds (SD = 4.9) to complete the suctioning sequences.

Implications for Practice:
Our results suggest that the guideline tested is safe and tolerated by infants.

Implications for Research:
This guideline should be tested in a larger sample and with neonates on other nasal CPAP systems.
Relationship Between Pityriasis Lichenoides and Mycosis Fungoides: A Clinicopathological, Immunohistochemical, and Molecular Study
Authors: Zaaroura Hiba , Sahar Dvora , Bick Tova , Bergman Reuven 
Published: November 2017

Background:
Several cases of pityriasis lichenoides (PL) have been reported to evolve into mycosis fungoides (MF).

Objective:
To elucidate clues to this progression.

Methods:
Fifty-eight patients with PL between 2000 and 2013 (follow-up: 3–16 years, average: 8.3).

Results:
A total of 3 (5.2%) of the 58 patients with PL developed MF after 3–11 years of prolonged clinical course. Papules and small plaques characterized PLs, and patches and larger plaques subsequent MFs. A total of 35 of 41 (85%) followed up non-MF associated patients with PL reported lasting complete remissions. Histopathologically, apoptotic keratinocytes disappeared mostly or completely in subsequent MFs. The presence of epidermotropism, folliculotropism, and epidermal lymphocytic nuclear atypia in PLs was not predictive of MF. CD8+ cells were the dominant intraepidermal lymphocytes in the 3 PLs but remained so in only 1 subsequent MF. CD7+ lymphocytes decreased substantially in 2 MFs, and lymphocytic nuclear atypia increased markedly in 1. T-cell receptor gene rearrangement studies demonstrated clonal populations in 1 of 2 studied PLs and in all 3 subsequent MFs.

Conclusions:
A few PLs may evolve into MF. Prolonged clinical course, appearance of patches and larger plaques, markedly increased lymphocytic nuclear atypia, marked diminution of apoptotic keratinocytes and CD7+ and CD8+ lymphocytes, and clonal T-cell receptor gene rearrangement may serve as clues.