bluuebunny/crossref_metadata_2025_split huggingface dataset:
Boys with fragile X syndrome: investigating temperament in early childhood
Authors: Low Kapalu C. M. , Gartstein M. A. 
Published: June 2016

AbstractBackgroundFragile X syndrome (FXS) is an x‐linked genetic disorder that represents the most common hereditary cause of Intellectual Disability (ID). Very specific behavioural features (e.g. attention deficit hyperactivity disorder and stereotyped behaviour) are associated with FXS in adolescents and adults, yet research on temperament and behavioural characteristics in young children with FXS has been more limited and less conclusive.MethodThis study investigated temperament differences in young boys (3–7 years old) with FXS (N = 26) recruited from a national FXS centre and controls (N = 26) matched on age, gender and race.ResultsCompared with controls, boys with FXS exhibited less overall surgency/extraversion and effortful control. Boys with FXS also displayed significantly greater activity and shyness and less attentional focusing, inhibitory control, soothability and high intensity pleasure (tendency to enjoy intense/complex activities), relative to comparison children. A significant interaction between age and diagnosis (FXS or control) was observed for negative affectivity only.ConclusionsAttention difficulties commonly found in adolescents and adults with FXS appear to also be characteristic of young boys with FXS, as reflected by lower effortful control. Age‐related findings concerning negative affectivity may be particularly significant, leading to improved intervention/preventative efforts.
Oriented inclusions of pyroxene, amphibole and rutile in garnet from the Lüliangshan garnet peridotite massif, North Qaidam UHPM belt, NW China: an electron backscatter diffraction study
Authors: Xu H. J. , Wu Y. 
Published: June 2016

AbstractOriented inclusions of clinopyroxene, orthopyroxene, sodic amphibole and rutile have been identified in garnet from the Lüliangshan garnet peridotite massif in the North Qaidam ultrahigh‐pressure metamorphic (UHPM) belt, northern Tibetan Plateau, NW China. Electron backscatter diffraction (EBSD) analyses demonstrate that nearly half of the measured intracrystalline clinopyroxene (8 out of 17) have topotactic crystallographic relationships with host garnet, that is, (100)Cpx//{112}Grt, (010)Cpx//{110}Grt and [001]Cpx//<111>Grt. One‐fifth of the oriented sodic amphibole (23 out of 110) inclusions of have topotactic crystallographic relationships with host garnet, that is, (010)Amp//{112}Grt, (100)Amp//{110}Grt and [001]Amp//<111>Grt. Over a third of rutile (36 out of 99) inclusions also show a close crystallographic orientation relationship with host garnet in that one <103>Rt and one <110>Rt parallel to two <111>Grt while the axes of [001]Rt exhibit small girdles centred the axes of <111>Grt. But, no ‘well‐fit’ crystallographic relationship was observed between orthopyroxene inclusions and host garnet. Considering a very long and complex history for the Lüliangshan garnet peridotite, we suggest that the low fit rates for these oriented minerals may result from several possible assumptions including different generations or multi‐stage formation mechanisms, heterogeneous nucleation and growth under non‐equilibrium conditions, and partial changes of initial crystallographic orientations of some inclusions. However, the residual quantitative ‘well‐fit’ crystallographic information is sufficient to indicate that the nucleation and growth of many pyroxene, amphibole and rutile are controlled by the lattice of the host garnet. The revealed close topotactic relationships accompanied by clear shape orientations provide quantitative microstructural evidence demonstrating a most likely exsolution/precipitate origin for at least some of the oriented phases of pyroxene, sodic amphibole and rutile from former majoritic garnet and support an ultra‐deep (>180 km depth) origin of the Lüliangshan garnet massif.
Comparison between the efficacy and safety of platelet‐rich plasma vs microdermabrasion in the treatment of striae distensae: clinical and histopathological study
Authors: Hersant Barbara , Niddam Jeremy , Meningaud Jean‐Paul 
Published: June 2016

SummaryThe article entitled “Comparison between the efficacy and safety of platelet‐rich plasma vs microdermabrasion in the treatment of striae distensae: clinical and histopathological study” (Zeinab Abd El‐Samad Ibrahim, et al.) is very interesting but the methodology is not robust. Our mains comments concerned the count of the cells, the activation of the PRP and the method of assessment.
The experience of people with dementia and nurses in hospital: an integrative review
Authors: Digby Robin , Lee Susan , Williams Allison 
Published: June 2016

Aims and objectivesTo identify and examine existing research exploring how people with dementia and nurses view acute hospital care.BackgroundAdmission to hospital can be traumatic for a person with dementia due to an inability to cope with unfamiliar environments, faces and routines. Adverse behavioural and health outcomes can result. Dementia adds complexity to patient care. Inability to deliver appropriate care is a source of stress and frustration for nurses.MethodsIntegrative review of the literature 2005–2015 reporting the experience of people with dementia and nurses caring for them in an acute hospital setting (n = 24).ResultsHospitals focus on acute medical care; consequently people with dementia are considered low priority and a disruption to normal routine. Risk management often takes priority over patient dignity. People with dementia are stigmatised. Families have significant roles to play in the care of a person with dementia in hospital but are often excluded. Nurses struggle to complete even basic patient care, and focus on tasks often at the expense of specific patient needs. Support for nurses is lacking. The job satisfaction of nurses caring for people with dementia is poor.ConclusionsNurses require improved education and support to care for patients with dementia. Hospitals must focus on genuine caring concurrently with rapid discharge requirements, risk mitigation and fiscal restraint. More research is needed to inform the development of appropriate care for people with dementia in hospitals.Relevance to clinical practiceNurses must understand the complex needs of people with dementia in hospital. Nurse education about dementia, practical support, strong clinical leadership and role‐modelling is needed. Empathy for patients regardless of diagnosis must remain a core attribute of nurses. Current hospital culture requires wider system review to mitigate against stigmatisation of patients with dementia.
An integrative review of skin assessment tools used to evaluate skin injury related to external beam radiation therapy
Authors: Baines Carol R , McGuiness William , O'Rourke Geraldine A 
Published: June 2016

Aims and objectivesTo review literature associated with external beam radiotherapy and skin damage. A focus of the literature search is to highlight and discuss the myriad of skin assessment tools that are available to the clinician when assessing skin injury in patients receiving external beam radiation therapy.BackgroundIt is apparent that despite considerable work being progressed in the development of individualised skin assessment tools, uptake and use is poor. These tools are designed to assist the clinician in the evaluation of damaged skin and predict the radiation wound development pathway.DesignAn integrated review can be used to address a mature or new and emerging topic through a systematic methodology, which is either theoretical or empirical, gained from research, practice or policy initiatives (Whittemore & Knafl, Journal of Advanced Nursing, 52, 2005, 546). This review is particularly concerned with the employment of skin assessment tools by clinicians in patients with radiation damaged skin. Using the search terms synonyms for radiation, skin and epidermal damage, PubMed/MEDLINE, Medical Complete and Web of Science databases were searched. Consulting professional peers was employed as part of the inclusion and exclusion process.ConclusionThere is a high level of unpredictability about which patient will have an uncomplicated course of external beam radiotherapy. Variables may include, but are not limited to, an acute reaction, a delayed reaction resulting in actual skin damage or no visible skin disturbance. The skin assessment tools that are readily available are not regularly referenced in clinical practice when attempting to manage the many side effects of radiation therapy. Skin assessment tools require ongoing clinical validation, so they can be used to guide practitioners to undertake further assessment of skin integrity.Relevance to clinical practiceThe current body of knowledge suggests clinicians caring for patients receiving therapeutic radiotherapy should consider integrating a recognised patient assessment skin framework into their daily routine. Such validated tools may add value to postradiotherapy patient care by providing a consistency of management and accordingly refining best practice.
Nurses' experience of caring for people with intellectual disability and dementia
Authors: Cleary Josephine , Doody Owen 
Published: June 2016

Aims and objectivesTo explore nurses' experiences of caring for older people with intellectual disability and dementia.BackgroundAgeing and dementia prevalence is increasing along with the life expectancy of people with intellectual disability. As a population group, people with intellectual disability have a high prevalence of dementia, which is higher within the subpopulation of Down syndrome. People with intellectual disability live in residential care, community or residential settings, and nurses are required to adapt their practices to meet the changed needs of the individual.DesignA qualitative Husserlian descriptive phenomenological methodology facilitated the researcher to become absorbed in the quintessence of meaning and explore nurses' experience of working with older people with intellectual disability and dementia.MethodsEthical approval was obtained, and data were collected utilising semistructured interviews (n = 11). Interviews were transcribed and analysed using Colaizzi's framework for data analysis.ResultsThree key themes were identified: ‘knowledge of dementia’, ‘person‐centred care’ and ‘transitioning within the service’. The study highlights the need for proactive planning, life story books of the patient, and funding to support client and staff.ConclusionsOverall, the study highlights the importance of knowing the person, supporting the individual and recognising presenting behaviours as outside the control of the individual.Relevance to clinical practiceThis article presents the experiences of nurses caring for the older person with intellectual disability and dementia. Transitions are often very difficult for both the person and their peers, and they experience benefit from the efforts of a multidisciplinary team facilitating a person‐centred approach.
Impact of teamwork on missed care in four Australian hospitals
Authors: Chapman Rose , Rahman Asheq , Courtney Mary , Chalmers Cheyne 
Published: June 2016

Aims and objectivesInvestigate effects of teamwork on missed nursing care across a healthcare network in Australia.BackgroundMissed care is universally used as an indicator of quality nursing care, however, little is known about mitigating effects of teamwork on these events.DesignA descriptive exploratory study.MethodsMissed Care and Team Work surveys were completed by 334 nurses. Using Stata software, nursing staff demographic information and components of missed care and teamwork were compared across the healthcare network. Statistical tests were performed to identify predicting factors for missed care.ResultsThe most commonly reported components of missed care were as follows: ambulation three times per day (43·3%), turning patient every two hours (29%) and mouth care (27·7%). The commonest reasons mentioned for missed care were as follows: inadequate labour resources (range 69·8–52·7%), followed by material resources (range 59·3–33·3%) and communication (range 39·3–27·2%). There were significant differences in missed care scores across units. Using the mean scores in regression correlation matrix, the negative relationship of missed care and teamwork was supported (r = −0·34, p < 0·001). Controlling for occupation of the staff member and staff characteristics in multiple regression models, teamwork alone accounted for about 9% of missed nursing care.ConclusionSimilar to previous international research findings, our results showed nursing teamwork significantly impacted on missed nursing care. Teamwork may be a mitigating factor to address missed care and future research is needed.Relevance to clinical practiceThese results may provide administrators, educators and clinicians with information to develop practices and policies to improve patient care internationally.
‘Feeling someone is there for you’ – experiences of women with vulvar neoplasia with care delivered by an Advanced Practice Nurse
Authors: Kobleder Andrea , Mayer Hanna , Senn Beate 
Published: June 2016

Aims and objectivesTo explore the experiences of women with vulvar neoplasia with care delivered by an Advanced Practice Nurse.BackgroundWomen with vulvar neoplasia suffer from a high number of symptoms and report a lack of information and support by health care professionals. Further, talking about their disease, which is still a social taboo, is difficult for them. From approaches for other patients, it can be suggested that support from an Advanced Practice Nurse can be helpful. For Advanced Practice Nurse development, implementation and evaluation, it is important to assess patients’ perceptions. But so far, little is known about how patients with vulvar neoplasia experience support of an Advanced Practice Nurse.DesignA qualitative interview study was chosen to gain understanding of the experience of women with vulvar neoplasia who received care delivered by an Advanced Practice Nurse.MethodsNarrative interviews were conducted with a purposive sample of 13 women with vulvar neoplasia after they received care from an Advanced Practice Nurse for six months. Thematic analysis was used to analyse the data from the interviews.ResultsFour main themes could be identified: a trusting relationship; accessibility; feeling safe and secure; and feeling someone is there for you. Women felt more secure and less alone in the experience of their illness through having the possibility of contacting an Advanced Practice Nurse and getting sufficient information and psychosocial support.ConclusionsWomen with vulvar neoplasia experienced care delivered by an Advanced Practice Nurse as ‘feeling someone is there for you’. Due to the localisation of the disease and the associated social taboo, psychosocial support from the Advanced Practice Nurse beyond months after surgery was very important for them.Relevance to clinical practiceAddressing psychosocial needs in caring for women with vulvar neoplasia must be given greater attention in clinical practice. Further, continuous nursing support delivered by an Advanced Practice Nurse beyond the acute treatment phase can be recommended.
Assessment of disease‐related knowledge and possible factors associated with the knowledge level among Chilean patients with inflammatory bowel disease
Authors: Simian Daniela , Flores Lilian , Quera Rodrigo , Kronberg Udo , Ibáñez Patricio , Figueroa Carolina , Lubascher Jaime 
Published: June 2016

Aims and objectivesTo assess disease‐related knowledge among patients with inflammatory bowel disease and to identify the factors that are possibly associated with the knowledge level.BackgroundDisease‐related knowledge can positively influence the acceptance of the disease, increase treatment compliance and improve the quality of life in patients with inflammatory bowel disease.DesignAn observational, cross‐sectional study was conducted and prospectively included patients from the inflammatory bowel disease programme between October 2014–July 2015.MethodsA Spanish‐translated version of the 24‐item Crohn's and Colitis Knowledge score was used to assess disease‐related knowledge. Patients also completed a demographic and clinical questionnaire.ResultsA total of 203 patients were included, 62% were female, and 66% were diagnosed with ulcerative colitis; the median age was 34 years (range 18–79), and the median disease duration was four years. The median disease‐related knowledge score was 9 (range 1–20). Only 29% of the patients answered more than 50% of the questions correctly. Lower disease‐related knowledge was observed in questions related to pregnancy/fertility and surgery/complications. Patients older than 50 years, with ulcerative colitis, with disease durations less than five years and patients without histories of surgery exhibited lower disease‐related knowledge. There was no association between the knowledge scores and the educational levels.ConclusionsThe patients who attended our inflammatory bowel disease programme exhibited poor disease‐related knowledge that was similar to the knowledge levels that have been observed in developed countries. It is necessary to assess patient knowledge to develop educational strategies and evaluate the influences of these strategies on patient compliance and quality of life.Relevance to clinical practiceThese results will allow the inflammatory bowel disease team to develop educational programmes that account for the disease‐related knowledge of each patient. Inflammatory bowel disease nurses should evaluate their interventions to provide evidence that educating our patients contributes to improving their treatment outcomes and overall health statuses.
An exploration of paediatric nurses’ views of caring for infants who have suffered nonaccidental injury
Authors: Barrett Emma , Denieffe Suzanne , Bergin Michael , Gooney Martina 
Published: June 2016

Aims and objectivesTo explore paediatric nurses’ views of caring for infants who have suffered nonaccidental injury.BackgroundChildren less than two years of age are at greater risk of serious abuse than those in any other age group. An infant's physical and mental immaturity makes them especially vulnerable. Abuse in this age group is often caused by a parent who does not report the abuse. The experience of caring for abused children is recognised as being both personally and professionally challenging. However, despite the increased risk of serious or fatal injury, caring for these infants who have suffered abuse is relatively unexplored.DesignA qualitative research design using purposive sampling was adopted. The setting for this research was a paediatric unit in Ireland.MethodSemi‐structured interviews were conducted with 10 paediatric nurses and data were analysed using the framework approach.ResultsPaediatric nurses’ views of caring for infants who have suffered a nonaccidental injury were established under four main themes: (1) ‘Personal impact’, (2) ‘Professional roles’, (3) ‘Nurse‐client relationship’ and (4) ‘Resources’.ConclusionFindings highlighted that the experience for the nurse is complex. Personal emotions are evoked and the experience influenced reflection on their own lives. Communication with the parents of the infant is often difficult. Professional relationships were sometimes hindered by poor sharing of information. However, nurses strived to maintain their professionalism and to provide nursing care for the infant and their parents that was holistic. Paediatric nurses relied heavily on each other for support and their nursing experience was a valuable resource for managing nonaccidental injuries.Relevance to clinical practiceThe general consensus was that a nurse could never fully be prepared to care for an infant who had suffered a nonaccidental injury. However, recommendations for future practice and education are identified and include frequent and practical education sessions.
From powerlessness to striving for control – experiences of invasive treatment while awake
Authors: Wermström Johanna , Ryrlén Eva , Axelsson Åsa B 
Published: June 2016

Aims and objectivesTo describe patients’ experiences of being cared for during invasive monitoring and treatment while awake.BackgroundPatients with acute heart failure treated in cardiac intensive care are awake during invasive monitoring and treatment and forced to remain in bed rest, sometimes for several days.DesignExploratory qualitative design.MethodEight patients were interviewed during invasive treatment. Analyses were conducted according to qualitative content analysis.ResultsThe participants described their way from a sense of powerlessness and striving to regain control when undergoing invasive monitoring and treatment. Due to their severe illness, they were exposed to the treatment implying a forced loss of empowerment. They surrendered to hospital care. To feel hope and resting from the illness helped the participants to endure the situation. When their condition improved, the need to regain control increased and they wanted to influence their daily care. The participants in present study did not desire to participate in decisions about the medical treatment, but wanted comprehensible information.ConclusionThis study shows how the patients’ illness forced them to surrender to the staff's knowledge and treatment. As the patients became more aware, it was important that the healthcare staff did not take over decisions and functions the patients could manage themselves. This helped the patients to endure.Relevance to clinical practiceThe result of present study could provide guidance for healthcare staff working with the patients cared for using invasive monitoring and treatment while they are awake. If staff has an increased insight of how the patients’ condition affects their ability to be involved, they have better understanding of the patients’ individual needs. Thus, the staff easier can respond to where the patients are in the process of powerlessness and striving to regain control.
Primary osteosarcoma of the uterine corpus: A case report
Authors: Tsukasaki Nanami , Mori Taisuke , Yasukawa Satoru , Konishi Eiichi , Kokabu Tetsuya , Kitawaki Jo 
Published: June 2016

AbstractPure osteosarcoma arising from the uterus is extremely rare. Only 15 cases of this type of cancer have been reported to date. Most patients showed local or lung metastasis early after surgery and died within a year of treatment initiation, regardless of multimodality therapy, indicating that this tumor is aggressive with a poor prognosis. Herein, we report the first clinical experience treated with a combination of docetaxel and gemcitabine for local and lung metastasis from primary osteosarcoma of the uterus. Although the disease was considered stable after three cycles of treatment, new metastatic lesions appeared in the lungs after six cycles. The patient was asymptomatic for 13 months; however, she died two months after symptom recurrence. Our case demonstrates that a combined regimen of docetaxel and gemcitabine may be a sound therapeutic option to control primary osteosarcoma of the uterus.