bluuebunny/crossref_metadata_2025_split huggingface dataset:
Continuous Transversus Abdominis Plane Nerve Blocks: Does Varying Local Anesthetic Delivery Method—Automatic Repeated Bolus Versus Continuous Basal Infusion—Influence the Extent of Sensation to Cold?: A Randomized, Triple-Masked, Crossover Study in Volunteers
Authors: Khatibi Bahareh , Said Engy T. , Sztain Jacklynn F. , Monahan Amanda M. , Gabriel Rodney A. , Furnish Timothy J. , Tran Johnathan T. , Donohue Michael C. , Ilfeld Brian M. 
Published: March 2017

BACKGROUND:
It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for transversus abdominis plane (TAP) catheters. We therefore tested the hypothesis that when using TAP catheters, providing local anesthetic in repeated bolus doses increases the cephalad-caudad cutaneous effects compared with a basal-only infusion.

METHODS:
Bilateral TAP catheters (posterior approach) were inserted in 24 healthy volunteers followed by ropivacaine 2 mg/mL administration for a total of 6 hours. The right side was randomly assigned to either a basal infusion (8 mL/h) or bolus doses (24 mL administered every 3 hours for a total of 2 bolus doses) in a double-masked manner. The left side received the alternate treatment. The primary end point was the extent of sensory deficit as measured by cool roller along the axillary line at hour 6 (6 hours after the local anesthetic administration was initiated). Secondary end points included the extent of sensory deficit as measured by cool roller and Von Frey filaments along the axillary line and along a transverse line at the level of the anterior superior iliac spine at hours 0 to 6.

RESULTS:
Although there were statistically significant differences between treatments within the earlier part of the administration period, by hour 6 the difference in extent of sensory deficit to cold failed to reach statistical significance along the axillary line (mean = 0.9 cm; SD = 6.8; 95% confidence interval –2.0 to 3.8; P = .515) and transverse line (mean = 2.5 cm; SD = 10.1; 95% confidence interval –1.8 to 6.8; P = .244). Although the difference between treatments was statistically significant at various early time points for the horizontal, vertical, and estimated area measurements of both cold and mechanical pressure sensory deficits, no comparison remained statistically significant by hour 6.

CONCLUSIONS:
No evidence was found in this study involving healthy volunteers to support the hypothesis that changing the local anesthetic administration technique (continuous basal versus hourly bolus) when using ropivacaine 0.2% and TAP catheters at 8 mL/h and 24 mL every 3 hours significantly influences the cutaneous effects after 6 hours of administration. Additional research is required to determine whether changing variables (eg, local anesthetic concentration, basal infusion rate, bolus dose volume, and/or interval) would provide different results.
Writing the Lives of Saints
Authors: Curtis Sarah A. 
Published: March 2017

AbstractThis article discusses the difficulty of access to the archives of women's religious orders in France based on the author's experiences and research. It argues that the reluctance that these orders often show in allowing outside researchers access to their records results from four overlapping and interlocking contexts: the impact of French culture wars during the Third Republic, the role of gender, the canonization policies of John Paul II, and the self-identification of religious orders as families whose history must remain private. Taken together, they strike at the heart of issues of trust, identity creation and reinforcement, and the relationship between private and public in the past and in the present. The purpose of this article is to reflect on the encounter between sister archivists and lay researchers as a way of thinking about archival practice and also of interrogating how the history of women religious has been conceptualized and studied.Cet article examine les problèmes d'accès aux archives des congrégations religieuses féminines à partir de l'expérience et des recherches de l'auteur. Il constate que la réticence que montrent souvent ces congrégations auprès des chercheurs non-congréganistes s'ensuit de quatre contextes liés : les conséquences des conflits entre l'Etat et l'Eglise pendant la Troisième République ; les rôles des sexes ; la politique de canonisation de Jean-Paul II ; et l'auto-identification des congrégations comme des familles pour lesquelles l'histoire doit rester privée. Ensemble, ces contextes vont au cœur des questions de la confiance, de la création et du renforcement des identités, et des rapports historiques et contemporains entre les sphères privée et publique. L'objectif de cet article est de réfléchir sur la rencontre entre les sœurs-archivistes et les chercheurs laïcs pour penser le problème des archives et aussi pour interroger la manière dont l'histoire des religieuses a été conçue et étudiée.
Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases
Authors: Lu Fei , Wu Xiaojun , Yin Feng , Chia-Fang Lee Christina , Yu Min , Mihaylov Ivailo S. , Yu Jiekai , Sun Hong , Zhang Hui 
Published: March 2017

ABSTRACTDNA replication licensing occurs on chromatin, but how the chromatin template is regulated for replication remains mostly unclear. Here, we have analyzed the requirement of histone methyltransferases for a specific type of replication: the DNA re-replication induced by the downregulation of either Geminin, an inhibitor of replication licensing protein CDT1, or the CRL4CDT2 ubiquitin E3 ligase. We found that siRNA-mediated reduction of essential components of the MLL-WDR5-RBBP5 methyltransferase complexes including WDR5 or RBBP5, which transfer methyl groups to histone H3 at K4 (H3K4), suppressed DNA re-replication and chromosomal polyploidy. Reduction of WDR5/RBBP5 also prevented the activation of H2AX checkpoint caused by re-replication, but not by ultraviolet or X-ray irradiation; and the components of MLL complexes co-localized with the origin recognition complex (ORC) and MCM2-7 replicative helicase complexes at replication origins to control the levels of methylated H3K4. Downregulation of WDR5 or RBBP5 reduced the methylated H3K4 and suppressed the recruitment of MCM2-7 complexes onto replication origins. Our studies indicate that the MLL complexes and H3K4 methylation are required for DNA replication but not for DNA damage repair.
Walking economy at simulated high altitude in human healthy young male lowlanders
Authors: Horiuchi Masahiro , Handa Yoko , Abe Daijiro , Fukuoka Yoshiyuki 
Published: March 2017

ABSTRACTWe measured oxygen consumption during walking per unit distance (Cw) values for 12 human healthy young males at six speeds from 0.667 to 1.639 m s−1 (four min per stage) on a level gradient under normobaric normoxia, moderate hypoxia (15% O2), and severe hypoxia (11% O2). Muscle deoxygenation (HHb) was measured at the vastus lateralis muscle using near-infrared spectroscopy. Economical speed which can minimize the Cw in each individual was calculated from a U-shaped relationship. We found a significantly slower economical speed (ES) under severe hypoxia [1.237 (0.056) m s−1; mean (s.d.)] compared to normoxia [1.334 (0.070) m s−1] and moderate hypoxia [1.314 (0.070) m s−1, P&lt;0.05 respectively] with no differences between normoxia and moderate hypoxia (P&gt;0.05). HHb gradually increased with increasing speed under severe hypoxia, while it did not increase under normoxia and moderate hypoxia. Changes in HHb between standing baseline and the final minute at faster gait speeds were significantly related to individual ES (r=0.393 at 1.250 m s−1, r=0.376 at 1.444 m s−1, and r=0.409 at 1.639 m s−1, P&lt;0.05, respectively). These results suggested that acute severe hypoxia slowed ES by ∼8%, but moderate hypoxia left ES unchanged.
The prevalence of psychological problems among ostomy patients: a cross-sectional study from Iran
Authors: Rafiei Hossein , Hoseinabadi-Farahani Mohammad Javad , Aghaei Sedigheh , Hosseinzadeh Kazem , Naseh Ladan , Heidari Mohammad 
Published: March 2017

Background and aims: Patients with chronic conditions often develop psychiatric disorders, most commonly depression, stress and anxiety, which may worsen the disease. This study examines the prevalence of depression, stress and anxiety among ostomy patients. Methods: A descriptive cross-sectional study was carried out, with participants selected using convenience sampling from all those who presented for follow up for routine stoma care in a wound clinic in Isfahan, Iran. Data were collected using a demographic variables checklist and the Depression, Anxiety, Stress Scale 21 (DASS-21). Results: Of the 70 participants, 51% were women and the rest were men. The mean age was 62.6 ± 14.1 years (range: 32–91 years). The mean scores for depression, anxiety and stress were 10.9 ± 5.4, 13.1±4.8 and 10.6 ± 5.8 respectively. In total, some level of depression, anxiety and stress was reported by 87%, 92.1% and 71% of patients respectively. Factors such as patients' sex, age, type of stoma and duration of living with stoma appeared to affect patients' levels of depression, anxiety and stress. Conclusion: The rate of psychological problems among ostomy patients is high. Health-care providers should be aware of this and plan for prevention. Further study in this regard is strongly recommended.
Changes in Eastern US Sawmill Employment and Estimated Hardwood Lumber Production from 2001 to 2015
Authors: Luppold William G. , Bumgardner Matthew S. 
Published: March 2017

Abstract
Sawmills are an important component of the hardwood industry, developing value-added products derived from the timber resources of the eastern United States. Employment in eastern sawmills has declined during the 21st century, reaching its lowest point in 2009 and 2010. Employment declines in the North and South Central regions of the United States were less than declines in the Northeast and Southeast regions, but East-wide employment was over 30 percent lower in 2010 than in 2001. The number of sawmills also has declined in the East, but since 2010, average employment in those mills has been increasing. Eastern hardwood lumber production followed sawmill employment for the four eastern subregions between 2001 and 2008; the last year estimates were available by state. Initial estimates of hardwood lumber production in 2009 based on production-to-employment ratios for the 2001 to 2008 period appeared higher than US Department of Agriculture estimates from timber product output data. A potential cause of this discrepancy was sawmills maintaining key employees during the Great Recession. After adjusting for these differences, eastern hardwood lumber production for 2009 was estimated to be 6.5 billion board feet (BBF), which was consistent with estimates of hardwood lumber consumption, net exports, and inventory adjustments. Eastern hardwood lumber production had increased to 9.2 BBF by 2015 but still was 28 percent less than the peak production year of 1999.
Hip region muscular dystrophy and emergence of motor deficits in dysferlin‐deficient Bla/J mice
Authors: Nagy Nadia , Nonneman Randal J. , Llanga Telmo , Dial Catherine F. , Riddick Natallia V. , Hampton Tom , Moy Sheryl S. , Lehtimäki Kimmo K. , Ahtoniemi Toni , Puoliväli Jukka , Windish Hillarie , Albrecht Douglas , Richard Isabelle , Hirsch Matthew L. 
Published: March 2017

AbstractThe identification of a dysferlin‐deficient animal model that accurately displays both the physiological and behavior aspects of human dysferlinopathy is critical for the evaluation of potential therapeutics. Disease progression in dysferlin‐deficient mice is relatively mild, compared to the debilitating human disease which manifests in impairment of particular motor functions. Since there are no other known models of dysferlinopathy in other species, locomotor proficiency and muscular anatomy through MRI (both lower leg and hip region) were evaluated in dysferlin‐deficient B6.A‐Dysfprmd/GeneJ (Bla/J) mice to define disease parameters for therapeutic assessment. Despite the early and progressive gluteal muscle dystrophy and significant fatty acid accumulation, the emergence of significant motor function deficits was apparent at approximately 1 year of age for standard motor challenges including the rotarod, a marble bury test, grip strength, and swimming speed. Earlier observations of decreased performance for Bla/J mice were evident during extended monitoring of overall exploration and rearing activity. Comprehensive treadmill gait analyses of the Bla/J model indicated significant differences in paw placement angles and stance in relation to speed and platform slope. At 18 months of age, there was no significant difference in the life expectancy of Bla/J mice compared to wild type. Consistent with progressive volume loss and fatty acid accumulation in the hip region observed by MRI, mass measurement of individual muscles confirmed gluteal and psoas muscles were the only muscles demonstrating a significant decrease in muscle mass, which is analogous to hip‐girdle weakness observed in human dysferlin‐deficient patients. Collectively, this longitudinal analysis identifies consistent disease parameters that can be indicators of efficacy in studies developing treatments for human dysferlin deficiency.
Genetic Insights into Ecological Succession from Oak- (Quercus robur L.) to Beech- (Fagus sylvatica L.) Dominated Forest Stands
Authors: Sandurska Elzbieta , Ulaszewski Bartosz , Burczyk Jaroslaw 
Published: March 2017

AbstractGenetic diversity is often considered a major determinant of long term population persistence and its potential to adapt to variable environmental conditions. The ability of populations to maintain their genetic diversity across generations seems to be a major prerequisite for their sustainability, which is particularly important for keystone forest tree species. However, little is known about genetic consequences of demographic alterations occurring during natural processes of ecological succession involving changes in the species composition. Using microsatellites, we investigated genetic diversity of adult and offspring generations in beech (Fagus sylvaticaL.) and oak (Quercus roburL.) populations coexisting in a naturally established old-growth forest stand, showing some symptoms of ongoing ecological succession from oak- to beech-dominated forest. In general, adult generations of both species exhibited high levels of genetic diversity (0.657 for beech; 0.821 for oak), which, however, depended on the sets of selected genetic markers. Nevertheless, several symptoms such as differences in genetic diversity indices between generations, significant levels of inbreeding (up to 0.029) and low estimates of effective population size (48–80) confirmed the declining status of the oak population. On the other hand, the uniform distribution of genetic diversity indices across generations, low levels of inbreeding (0.004), low genetic differentiation among adults and offspring and, most importantly, large estimates of effective population size (119–716), all supported beech as a successive and successful tree species in the studied forest stand.
Bird ringing in Slovenia in 2015 and the occurrence of Parrot Crossbills Loxia pytyopsittacus
Authors: Vrezec Al , Fekonja Dare 
Published: March 2017

Abstract
In 2015, 170 bird species were recorded during bird ringing activities in Slovenia. We ringed 73,371 birds belonging to 162 species, there were 132 foreign recoveries of birds ringed in Slovenia, 120 recoveries of birds ringed abroad and found in Slovenia, as well as 1964 local recoveries. The most frequently ringed species were Blackcap Sylvia atricapilla and Great Tit Parus major. In ringed nestlings, Great Tits and Tree Sparrows Passer montanus predominated. In 2015, the first preliminary ringing of Scops Owls Otus scops during migration took place, resulting in the highest number of Scops Owls ringed so far. Concerning recoveries of birds ringed in Slovenia and later recorded abroad and birds ringed abroad and later recorded in Slovenia, the commonest were Mute Swans Cygnus olor and Black-headed Gulls Chroicocephalus ridibundus. The longest-distance recovery concerned a Reed Bunting Emberiza schoeniculus found in Sweden (2,144 km away). Among the interesting finds were also the first finds of ringed Pygmy Cormorants Microcarbo pygmeus so far from breeding sites in Hungary. Among rare species, Yellow-browed Warbler Phylloscopus inornatus, Spanish Sparrow Passer hispaniolensis and a pair of Parrot Crossbills Loxia pytyopsittacus were caught and ringed, the latter for the very first time in Slovenia after more than 100 years. An overview of records of the Parrot Crossbill is given herein, as well as analysis of irruptive years of the Red Crossbills Loxia curvirostra between 1980 and 2015, when the probability of boreal Crossbill species occurrence is the highest. According to the ringers’ data, the irruptive years of Red Crossbills in Slovenia were 1984, 1985, 2007, 2008, 2010, 2011 and 2012. The article points to the probability that Parrot Crossbills have been overlooked in the past, since larger specimens of Crossbills were ringed mostly in irruptive years, but no specific bill measurements important for distinguishing between Parrot and Red Crossbill had been taken.
Assessment of the Possibility of Using Reclaimed Materials for Making Cores by the Blowing Method
Authors: Dańko R. , Dańko J. , Skrzyński M. 
Published: March 2017

Abstract
The cumulative results of investigations of the possibility of using the reclaimed materials after the mechanical, thermal or mechanical-thermal reclamation for making cores by means of the blowing method in the alkaline CO2 technology, are presented in the paper. Three kinds of spent sands: with furfuryl resin, bentonite and alkaline phenolic resin, obtained from the foundry, were subjected to three kinds of reclamation: mechanical, thermal and combined mechanical-thermal, applying for this aim adequate experimental devices. The obtained reclaims were assessed with regard to the degree of the matrix liberation from the determined binding material. Reclaims of moulding sands with binders of the form of resin were assessed with regard to ignition loss values and pH reaction, while reclaims of moulding sands with bentonite with regard to the residual clay content and pH value. In all cases the results of the performed sieve analyses were estimated and the average characteristic diameter dl was determined. The reclaimed matrix was applied as a full substitute of the fresh high-silica sand in typical procedures of preparing core sands used for making shaped samples for bending strength investigations, Rgu.
Development of a New ATD-P Tester for Hard Wear Resistant Materials
Authors: Dojka M. , Dojka R. , Studnicki A. 
Published: March 2017

Abstract
The aim of presented studies was to develop a new geometry of the overflow part of standard ATD-C tester for derivative thermal analysis in a way that it would allow to obtain samples for abrasion and mechanical properties tests in the same mould without the need of cutting them from a block of material. The pattern of new ATD-P tester has parts reflecting implemented samples. Computer simulations regarding initial verification of new tester were performed in NovaFlow software. Chromium cast iron melts were made for testing the sampler in real conditions and TDA analysis for casting material were conducted. The sandmix was prepared on silica sand matrix per the ALPHASET technology. This new solution greatly simplifies the preparations of materials difficult to machine.
Studies on the Gases Emission under High Temperature Condition from Moulding Sands Bonded by Modified Starch CMS-Na
Authors: Kaczmarska K. , Bobrowski A. , Żymankowska-Kumon S. , Grabowska B. 
Published: March 2017

Abstract
Emission of gases under high temperature after pouring molten metal into moulds, which contain the organic binder or other additives (solvents or curing agent), may be an important factor influencing both on the quality of the produced castings, and on the state of environment. Therefore, a comprehensive study of the emitted gases would allow to determine restrictions on the use of the moulding sands in foundry technologies, eg. the probability of occurrence of casting defects, and identify the gaseous pollutants emitted to the environment. The aim of the research presented in this paper was to determine the amount of gases that are released at high temperatures from moulding sands bonded by biopolymer binder and the quantitative assessment of the emitted pollutants with particular emphasis on chemical compounds: benzene, toluene, ethylbenzene and xylenes (BTEX). The water-soluble modified potato starch as a sodium carboxymethyl starch with low (CMS-NaL) or high (CMS-NaH) degree of substitution was a binder in the tested moulding sands. A tests of gases emission level were conducted per the procedure developed at the Faculty of Foundry Engineering (AGH University of Science and Technology) involving gas chromatography method (GC). The obtained results of the determination of amount of BTEX compounds generated during the decomposition process of starch binders showed lower emission of aromatic hydrocarbons in comparison with binder based on resin Kaltharz U404 with the acidic curing agent commonly used in the foundries.
Air Emissions of Selected Substances from Particular Sectors Including Metallurgy in Poland
Authors: Kargulewicz I. 
Published: March 2017

Abstract
This article presents data on the anthropogenic air emissions of selected substances (CO2, SO2, total suspended particles (TSP), dioxins and furans (PCDD/F), Pb and Cd) subject to reporting under the Climate Convention (UNFCCC) or the Convention on Long-range Transboundary Air Pollution (UNECE CLRTAP). It also presents the national emissions of these substances in 2014 by the major source categories and defines the share of metal production in these emissions. Analysis is based on national emission inventory reports. Most important source of air emission in case of CO2 and SO2 is 1.A.1 Energy industries category. TSP and PCDD/F are emitted mainly from fuel combustion in small sources (i.a. households). Emission of heavy metals (Pb and Cd) is connected mostly with 1.A.2. Manufacturing industries and construction category. Metallurgy is significant source of emission only for lead and cadmium from among all considered substances. The shares of particular sectors in the national emissions of given pollutants are important, in view of the possible reduction measures and the determination in which industries they could bring about tangible results.