bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inductions of reproduction and population growth in the generalist predator Cyrtorhinus lividipennis (Hemiptera: Miridae) exposed to sub‐lethal concentrations of insecticides
Authors: Lu Weiwei , Xu Qiujing , Zhu Jun , Liu Chen , Ge Linquan , Yang Guoqing , Liu Fang 
Published: January 2017

AbstractBACKGROUNDThe miridbug, Cyrtorhinus lividipennis, is a significant predacious enemy of rice planthoppers. The effects of sub‐lethal concentrations of triazophos, deltamethrin and imidacloprid on fecundity, egg hatchability, expression levels of genes associated with reproduction, and population growth in C. lividipennis were investigated.RESULTSThe fecundities for three pair combinations (♀c × ♂t, ♀t × ♂c and ♀t × ♂t) treated with sub‐lethal concentrations of the insecticides triazophos, deltamethrin and imidacloprid (LC10 and LC20) showed a significant increase compared to the untreated pairs (♀c × ♂c). However, sub‐lethal concentration treatments did not affect the egg hatchability. The ClVg expression levels of female adults exposed to triazophos, deltamethrin and imidacloprid (LC20) increased by 52.6, 48.9 and 91.2%, respectively. The ClSPATA13 expression level of adult males exposed to triazophos, deltamethrim and imidacloprid (LC20) increased by 80.7, 41.3 and 48.3%, respectively. Furthermore, sub‐lethal concentrations of insecticides (LC20) caused increased population numbers in C. lividipennis.CONCLUSIONSub‐lethal concentrations of triazophos, deltamethrin and imidacloprid stimulated reproduction and enhanced population growth of C. lividipennis. The reproductive stimulation might result from the up‐regulation of ClVg or ClSPATA13. These findings may be useful in mediating populations of planthoppers. © 2017 Society of Chemical Industry
Pesticide exposure assessment for surface waters in the EU. Part 2: Determination of statistically based run‐off and drainage scenarios for Germany
Authors: Bach Martin , Diesner Mirjam , Großmann Dietlinde , Guerniche Djamal , Hommen Udo , Klein Michael , Kubiak Roland , Müller Alexandra , Preuss Thomas G , Priegnitz Jan , Reichenberger Stefan , Thomas Kai , Trapp Matthias 
Published: January 2017

AbstractBACKGROUNDIn order to assess surface water exposure to active substances of plant protection products (PPPs) in the European Union (EU), the FOCUS (FOrum for the Co‐ordination of pesticide fate models and their USe) surface water workgroup introduced four run‐off and six drainage scenarios for Step 3 of the tiered FOCUSsw approach. These scenarios may not necessarily represent realistic worst‐case situations for the different Member States of the EU. Hence, the suitability of the scenarios for risk assessment in the national authorisation procedures is not known.RESULTSUsing Germany as an example, the paper illustrates how national soil–climate scenarios can be developed to model entries of active substances into surface waters from run‐off and erosion (using the model PRZM) and from drainage (using the model MACRO). In the authorisation procedure for PPPs on Member State level, such soil–climate scenarios can be used to determine exposure endpoints with a defined overall percentile.CONCLUSIONThe approach allows the development of national specific soil–climate scenarios and to calculate percentile‐based exposure endpoints. The scenarios have been integrated into a software tool analogous to FOCUS‐SWASH which can be used in the future to assess surface water exposure in authorisation procedures of PPPs in Germany. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Robotic versus open liver resections: A case‐matched comparison
Authors: Morel Philippe , Jung Minoa , Cornateanu Sorina , Buehler Leo , Majno Pietro , Toso Christian , Buchs Nicolas C. , Rubbia‐Brandt Laura , Hagen Monika E. 
Published: January 2017

AbstractBackgroundMost hepatic resections are currently performed using an open approach. Robotic surgery might enable the transition of these procedures to minimally invasive surgery.MethodsPre‐, peri‐ and post‐operative data of all patients who underwent a liver resection from 2009/2012 to 2001/2015, were collected prospectively. All robotic resection patients were matched 1:1 to patients who underwent open surgery. Pre‐ and perioperative data, up to 30 days, were analyzed.ResultsSixteen robotic and open hepatic resections were identified. Fewer complication events and shorter lengths of stay (LOS, 7.9 versus 11 days, P = 0.0603) were observed for robotic resections. Length of stay in the intermediate care unit (IMC) was shorter after the robotic procedure (10 h vs 16.6 h, P = 0.0699). Operating room (OR) time was significantly longer in the robotic resection cohort (352.8 vs 239.6 min, P = 0.0215). All tumor margins were negative.ConclusionsThis preliminary comparison demonstrates the general feasibility of minor robotic liver resection in selected cases.
Critical Social Theory and Sustainable Development: The Role of Class, Capitalism and Domination in a Dialectical Analysis of Un/Sustainability
Authors: Fuchs Christian 
Published: January 2017

AbstractIt is still a relatively open question if and how sustainability fits into a critical theory of society. This paper's aim is to makes a contribution to the critical social theory foundations of sustainability and to reflect on the links between capitalism, class and sustainability. Sustainability has not been a very popular concept in sociological theory. One of the reasons may be that sociology has a strongly critical tradition focusing on the analysis and critique of power structures in modern society. It is therefore often sceptical of ideas coming from the policy world that are susceptible to having an administrative character. The article argues that, although sustainability has a strongly ideological character, a critical theory of society should not simply discard this notion, but aim to sublate it. Some foundations of a way to integrate sustainability into a critical theory of society are presented. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
JDAS: a software development framework for multidatabases
Authors: Xie Guoqi , Chen Yuekun , Liu Yan , Fan Chunnian , Li Renfa , Li Keqin 
Published: January 2017

SummaryModern software development for services computing and cloud computing software systems is no longer based on a single database but on existing multidatabases and this convergence needs new software architecture and framework design. Most current popular frameworks are not designed for multidatabases, and many practical problems in development arise. This study designs and implements a software development framework called Java data access service (JDAS) for multidatabases using the object‐oriented programming language Java. The JDAS framework solves related problems that arise when other frameworks are employed in practical software development with multidatabases by presenting and introducing design methods. JDAS consists of the modules of the database abstract, object relational mapping, connection pools management, configuration management, data access service, and inversion of control. Results and case study reveal that the JDAS framework effectively reduces development complexity and improves development efficiency of the software systems with multidatabases. Copyright © 2017 John Wiley & Sons, Ltd.
Adsorption Behavior of Fatty Alcohol Ether Sulfonate at Different Interfaces
Authors: Liu Xiaochen , Zhao Yongxiang , Li Qiuxiao , Jiao Tiliu , Niu Jinping 
Published: January 2017

AbstractThe equilibrium surface tension, dynamic surface tension, and interfacial tension (IFT) of fatty alcohol ether sulfonates (CmEnSO) were measured to investigate their adsorption behavior. The effect of NaCl and CaCl2 concentrations on the IFT was also studied. The results showed that the number of EO units has no significant effect on the critical micelle concentration (CMC) and CMC decreases with increasing the length of the hydrophobic group. The surface tension at the CMC increases with the increase of the number of EO units and the length of the hydrophobic group. At dilute surfactant concentration, the adsorption process for CmEnSO is controlled by diffusion; at higher concentration, it becomes a mixed diffusion‐kinetic adsorption mechanism. The IFT between CmEnSO solution and dodecane remains around 10−1 mN/m over a wide range of electrolyte concentrations (NaCl concentration from 25 to 210 g/L, CaCl2 concentration from 0.1 to 10 g/L).
Current issues and future research priorities for health economic modelling across the full continuum of Alzheimer's disease
Authors: Gustavsson Anders , Green Colin , Jones Roy W. , Förstl Hans , Simsek Deniz , de Reydet de Vulpillieres Frederic , Luthman Stefanie , Adlard Nicholas , Bhattacharyya Subrata , Wimo Anders 
Published: January 2017

AbstractAvailable data and models for the health‐economic evaluation of treatment in Alzheimer's disease (AD) have limitations causing uncertainty to decision makers. Forthcoming treatment strategies in preclinical or early AD warrant an update on the challenges associated with their economic evaluation. The perspectives of the co‐authors were complemented with a targeted review of literature discussing methodological issues and data gaps in AD health‐economic modelling. The methods and data available to translate treatment efficacy in early disease into long‐term outcomes of relevance to policy makers and payers are limited. Current long‐term large‐scale data accurately representing the continuous, multifaceted, and heterogeneous disease process are missing. The potential effect of disease‐modifying treatment on key long‐term outcomes such as institutionalization and death is uncertain but may have great effect on cost‐effectiveness. Future research should give priority to collaborative efforts to access better data on the natural progression of AD and its association with key long‐term outcomes.
Standards for Clinical Trials in Male and Female Sexual Dysfunction: IV. Unique Aspects of Clinical Trials in Female Sexual Dysfunction
Authors: Fisher William A. , Gruenwald Ilan , Jannini Emmanuele A. , Lev-Sagie Ahinoam , Lowenstein Lior , Pyke Robert E. , Reisman Yakov , Revicki Dennis A. , Rubio-Aurioles Eusebio 
Published: January 2017

Abstract

The focus of this article, the fourth in the series, Standards for Clinical Trials in Male and Female Sexual Dysfunction, is on aspects of clinical trial design and measurement that are specific to clinical trials for treatments of female sexual dysfunction. Challenges in this area include the limited extent of treatment development and clinical trial research across the spectrum of female sexual dysfunctions, changing regulatory considerations, changing diagnostic criteria for female sexual dysfunction, and the need to articulate assessment procedures to these changes. Discussion focuses on approaches to addressing these challenges in clinical trials in female sexual dysfunction.
Role of Nanotechnology in Erectile Dysfunction Treatment
Authors: Wang Alice Y. , Podlasek Carol A. 
Published: January 2017

Abstract

Introduction
The biological importance of nanotechnology-based delivery vehicles for in vivo tissue regeneration is gaining acceptance by the medical community; however, its relevance and incorporation into the treatment of sexual dysfunction are evolving and have not been well evaluated.

Aim
To provide scientific evidence examining the use of state-of-the-art nanotechnology-based delivery methodology in the treatment of erectile dysfunction (ED) in animal models and in patients.

Methods
This review assessed the current basic science literature examining the role of nanotechnology-based delivery vehicles in the development of potential ED therapies.

Results
There are four primary areas where nanotechnology has been applied for ED treatment: (i) topical delivery of drugs for on-demand erectile function, (ii) injectable gels into the penis to prevent morphologic changes after prostatectomy, (iii) hydrogels to promote cavernous nerve regeneration or neuroprotection, and (iv) encapsulation of drugs to increase erectile function (primarily of phosphodiesterase type 5 inhibitors).

Conclusion
Basic science studies provide evidence for a significant and evolving role for nanotechnology in the development of therapies for ED and suggest that properly administered nano-based therapies might be advantageous for treating male sexual dysfunction.
Corrigendum and Addendum: Abstract M- and Abstract L-Spaces of Polynomials on Banach Lattices
Authors: Bu Qingying , Buskes Gerard , Li Yongjin 
Published: January 2017

AbstractIn this short note, we correct and reformulate Theorem 3.1 in the paper published in Proceedings of the Edinburgh Mathematical Society58(3) (2015), 617–629.
Neuroanatomy of Gryposuchus neogaeus (Crocodylia, Gavialoidea): a first integral description of the braincase and endocranial morphological variation in extinct and extant gavialoids
Authors: Bona Paula , Paulina Carabajal Ariana , Gasparini Zulma 
Published: January 2017

ABSTRACTMorphological studies of the braincase and cranial endocast of fossil crocodylians, especially gavialids, are scarce. Here, we present a detailed description of the neuroanatomy of Gryposuchus neogaeus from the Miocene of Argentina, based on CT scans. The cranial endocast is sub-horizontal and the angle formed between the mid-brain and the hind-brain is poorly marked. When compared with Gavialis gangeticus, the mid-brain of G. neogaeus is relatively shorter, although the distribution of cranial nerves is similar. In the floor of the endocranial cavity, posterior to the dorsum sellae, there is a median foramen that leads into a canal that runs anteroventrally through the basisphenoid to penetrate the posterior wall of the pituitary fossa (open foramen for the basilar artery?). The same structure is present in G. gangeticus, but is absent in other living crocodylians, suggesting a potential synapomorphy of Gavialoidea. The pneumaticity of the skull roof and the lateral branches of the pharyngotympanic system in G. neogaeus are markedly reduced when compared with the extant species. Comparisons with the living Gavialis indicate that the pattern of braincase morphology of Gavialidae was present in the Miocene; however, the internal morphology, including brain shape, pneumaticity of the skull roof and basicranium, is different in the two species. This work is the first step to understand the variation of the neuroanatomy in this group of archosaurs and its palaeobiological implication.
Morpho-functional analysis of the mastoid region of the extinct South American mustelid †Stipanicicia pettorutii
Authors: Ercoli Marcos D. 
Published: January 2017

ABSTRACTThe morphology of the mastoid region in predators is informative about the hunting strategies and capacity of carrying prey. The purpose of this research was to describe the mastoid region and reconstruct the associated musculature of †Stipanicicia pettorutii Reig, 1956, a Pleistocene weasel with a distinctive morphology compared to its living relatives, and to make inferences about its predatory abilities. Galictis, a living weasel closely related to Stipanicicia, as well as other carnivorans, were used as comparative models. The muscle insertions identified in Stipanicicia presented a similar or larger development than Galictis. The insertion area of the muscles obliquus capitis cranialis, longissimus capitis, sternocephalicus pars mastoidea and cleidocephalicus pars mastoidea were found to be markedly developed and in a lateralised position with respect to the atlanto–occipital joint in hyaenids and mustelids, and especially in Stipanicicia, suggesting powerful lateral flexion and rotation movements in the fossil. The larger degree of advancement of the mastoid process in mustelids, and secondary in felids, would allow a powerful ventral flexion of the head. Stipanicicia would have exhibited powerful lateral movements and retraction of the head and neck, over restricted extension movements and, therefore, would have been a weasel specialised in subjugating and carrying prey of a relatively large size.
Validation of the Continuous Tracking Paradigm for Studying Implicit	Motor Learning
Authors: Künzell Stefan , Sießmeir Dominicus , Ewolds Harald 
Published: January 2017

Abstract. A continuous pursuit-tracking task is the typical experimental paradigm to investigate implicit motor learning. Implicit motor learning is proven by a greater improvement in tracking of a repeated segment of a target path compared to random segments ( Pew, 1974 ). Recently, doubts about the validity of results obtained with this paradigm have been raised. Improved tracking of a repeated segment might simply be due to the characteristics of that particular segment. In response to these doubts, we seek to improve the continuous tracking task. Therefore, we computed a pool of 37 distinct target segments. Participants (N = 36) practiced the tracking task, each one with a unique repeated segment in the middle and varying outer segments, all taken from the pool of segments. After five practice blocks of 36 trials each, a test block was performed where the repeated middle segment was replaced with a random segment. The tracking performance on the repeated segment was better than on random segments. Furthermore, we assume that learning was implicit, because participants’ answers to a posttest interview showed they were largely unaware of a repeated segment within the curves.
Genomic repertoire of the Woeseiaceae/JTB255, cosmopolitan and abundant core members of microbial communities in marine sediments
Authors: Mußmann Marc , Pjevac Petra , Krüger Karen , Dyksma Stefan 
Published: January 2017

Abstract
To date, very little is known about the bacterial core community of marine sediments. Here we study the environmental distribution, abundance and ecogenomics of the gammaproteobacterial Woeseiaceae/JTB255 marine benthic group. A meta-analysis of published work shows that the Woeseiaceae/JTB255 are ubiquitous and consistently rank among the most abundant 16S rRNA gene sequences in diverse marine sediments. They account for up to 22% of bacterial amplicons and 6% of total cell counts in European and Australian coastal sediments. The analysis of a single-cell genome, metagenomic bins and the genome of the next cultured relative Woeseia oceani indicated a broad physiological range, including heterotrophy and facultative autotrophy. All tested (meta)genomes encode a truncated denitrification pathway to nitrous oxide. The broad range of energy-yielding metabolisms possibly explains the ubiquity and high abundance of Woeseiaceae/JTB255 in marine sediments, where they carry out diverse, but yet unknown ecological functions.
Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
Authors: Ehrnstorfer Ines A. , Manatschal Cristina , Arnold Fabian M. , Laederach Juerg , Dutzler Raimund 
Published: January 2017

AbstractSecondary active transporters of the SLC11/NRAMP family catalyse the uptake of iron and manganese into cells. These proteins are highly conserved across all kingdoms of life and thus likely share a common transport mechanism. Here we describe the structural and functional properties of the prokaryotic SLC11 transporter EcoDMT. Its crystal structure reveals a previously unknown outward-facing state of the protein family. In proteoliposomes EcoDMT mediates proton-coupled uptake of manganese at low micromolar concentrations. Mutants of residues in the transition-metal ion-binding site severely affect transport, whereas a mutation of a conserved histidine located near this site results in metal ion transport that appears uncoupled to proton transport. Combined with previous results, our study defines the conformational changes underlying transition-metal ion transport in the SLC11 family and it provides molecular insight to its coupling to protons.
Hampering Effect of Cholesterol on the Permeation of Reactive Oxygen Species through Phospholipids Bilayer: Possible Explanation for Plasma Cancer Selectivity
Authors: Van der Paal Jonas , Verheyen Claudia , Neyts Erik C. , Bogaerts Annemie 
Published: January 2017

AbstractIn recent years, the ability of cold atmospheric pressure plasmas (CAPS) to selectively induce cell death in cancer cells has been widely established. This selectivity has been assigned to the reactive oxygen and nitrogen species (RONS) created in CAPs. To provide new insights in the search for an explanation for the observed selectivity, we calculate the transfer free energy of multiple ROS across membranes containing a varying amount of cholesterol. The cholesterol fraction is investigated as a selectivity parameter because membranes of cancer cells are known to contain lower fractions of cholesterol compared to healthy cells. We find that cholesterol has a significant effect on the permeation of reactive species across a membrane. Indeed, depending on the specific reactive species, an increasing cholesterol fraction can lead to (i) an increase of the transfer free energy barrier height and width, (ii) the formation of a local free energy minimum in the center of the membrane and (iii) the creation of extra free energy barriers due to the bulky sterol rings. In the context of plasma oncology, these observations suggest that the increased ingress of RONS in cancer cells can be explained by the decreased cholesterol fraction of their cell membrane.
NMR reveals a dynamic allosteric pathway in thrombin
Authors: Handley Lindsey D. , Fuglestad Brian , Stearns Kyle , Tonelli Marco , Fenwick R. Bryn , Markwick Phineus R. L. , Komives Elizabeth A. 
Published: January 2017

AbstractAlthough serine proteases are found ubiquitously in both eukaryotes and prokaryotes, and they comprise the largest of all of the peptidase families, their dynamic motions remain obscure. The backbone dynamics of the coagulation serine protease, apo-thrombin (S195M-thrombin), were compared to the substrate-bound form (PPACK-thrombin). R1, R2, 15N-{1H}NOEs, and relaxation dispersion NMR experiments were measured to capture motions across the ps to ms timescale. The ps-ns motions were not significantly altered upon substrate binding. The relaxation dispersion data revealed that apo-thrombin is highly dynamic, with μs-ms motions throughout the molecule. The region around the N-terminus of the heavy chain, the Na+-binding loop, and the 170 s loop, all of which are implicated in allosteric coupling between effector binding sites and the active site, were dynamic primarily in the apo-form. Most of the loops surrounding the active site become more ordered upon PPACK-binding, but residues in the N-terminal part of the heavy chain, the γ-loop, and anion-binding exosite 1, the main allosteric binding site, retain μs-ms motions. These residues form a dynamic allosteric pathway connecting the active site to the main allosteric site that remains in the substrate-bound form.
Synthesis and insecticidal activity of acridone derivatives to Aedes aegypti and Culex quinquefasciatus larvae and non-target aquatic species
Authors: Roopan Selvaraj Mohana , Bharathi Annadurai , Al-Dhabi Naif Abdullah , Arasu Mariadhas Valan , Madhumitha G. 
Published: January 2017

AbstractA serious Mosquito borne yellow fever is one of the grave diseases which affect the major population. Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against A. aegypti and C. quinquefasciatus, respectively. Also the active products were treated to check the mortality of non-target aquatic species. Through the reports of the larvicidal bioassay, compounds 3b against C. quinquefasciatus whereas 5c against A. aegypti were found to be more active. By keeping this as a platform, further extension of the work can be done to find out a valuable drug for controlling disease vectors.