bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update
Authors: Hesketh Paul J. , Kris Mark G. , Basch Ethan , Bohlke Kari , Barbour Sally Y. , Clark-Snow Rebecca Anne , Danso Michael A. , Dennis Kristopher , Dupuis L. Lee , Dusetzina Stacie B. , Eng Cathy , Feyer Petra C. , Jordan Karin , Noonan Kimberly , Sparacio Dee , Somerfield Mark R. , Lyman Gary H. 
Published: July 2017

Purpose To update the ASCO guideline for antiemetics in oncology. Methods ASCO convened an Expert Panel and conducted a systematic review of the medical literature for the period of November 2009 to June 2016. Results Forty-one publications were included in this systematic review. A phase III randomized controlled trial demonstrated that adding olanzapine to antiemetic prophylaxis reduces the likelihood of nausea among adult patients who are treated with high emetic risk antineoplastic agents. Randomized controlled trials also support an expanded role for neurokinin 1 receptor antagonists in patients who are treated with chemotherapy. Recommendation Key updates include the addition of olanzapine to antiemetic regimens for adults who receive high-emetic-risk antineoplastic agents or who experience breakthrough nausea and vomiting; a recommendation to administer dexamethasone on day 1 only for adults who receive anthracycline and cyclophosphamide chemotherapy; and the addition of a neurokinin 1 receptor antagonist for adults who receive carboplatin area under the curve ≥ 4 mg/mL per minute or high-dose chemotherapy, and for pediatric patients who receive high-emetic-risk antineoplastic agents. For radiation-induced nausea and vomiting, adjustments were made to anatomic regions, risk levels, and antiemetic administration schedules. Rescue therapy alone is now recommended for low-emetic-risk radiation therapy. The Expert Panel reiterated the importance of using the most effective antiemetic regimens that are appropriate for antineoplastic agents or radiotherapy being administered. Such regimens should be used with initial treatment, rather than first assessing the patient’s emetic response with less-effective treatment. Additional information is available at www.asco.org/supportive-care-guidelines and www.asco.org/guidelineswiki .
Exact Approaches for Designing Multifacility Buy-at-Bulk Networks
Authors: Arulselvan Ashwin , Rezapour Mohsen , Welz Wolfgang A. 
Published: July 2017

We study a problem that integrates buy-at-bulk network design into the classical facility location problem. We consider a generalization of the facility location problem where multiple clients may share a capacitated network to connect to open facilities instead of requiring direct links. In this problem, we wish to open facilities, build a routing network by installing access cables of different costs and capacities, and route every client demand to an open facility. We provide a path-based formulation and we compare it with the natural compact formulation for this problem. We then design an exact branch-price-and-cut algorithm for solving the path-based formulation. We study the effect of two families of valid inequalities. In addition to this, we present three different types of primal heuristics and employ a hybrid approach to effectively combine these heuristics in order to improve the primal bounds. We finally report the results of our approach that were tested on a set of real world instances, as well as two sets of benchmark instances and evaluate the effects of our valid inequalities and primal heuristics.
Gestão Democrática na Escola Pública Contemporânea
Authors: Carvalho Tereza Priscila Silva Oliveira , Costa Liliany Souza , Alexandre Lucimara Araújo Campos 
Published: July 2017

O objetivo geral deste artigo é descrever como acontece a gestão democrática e suas contribuições para a melhoria do desempenho organizacional, funcional e resultados alcançados na Escola Simão Angelo. A problemática: saber como a gestão democrática está acontecendo na escola e como a descentralização, participação e transparência podem aumentando a qualidade e efetividade do ensino. A metodológica é exploratória qualitativa/ quantitativa. A técnica de coleta de dados utiliza observações, análises documentais, entrevista para os segmentos da escolar. Será realizada uma revisão bibliográfica por meio de leitura de teóricos que tratam do processo de gestão democrática da escola pública, possibilitando uma maior fundamentação do problema investigado. O interesse pela pesquisa surgiu da necessidade de conhecer como o núcleo gestor da escola pratica a gestão democrática para conquistar uma educação ideal. Os resultados demonstraram que os gestores e demais segmentos conhecem e vivenciam os princípios da gestão democrática no cotidiano escolar. Palavras-chave: Gestão Democrática. Escola Pública. Participação. Resultados.
Analisis Kinematis untuk Menentukan Dimensi Transfemoral Prosthetic Tipe Four-Bar Linkage dalam Fase Awal Siklus Gait Cycle
Authors: Sugiyanto Sugiyanto , P. Biyan B. , P. Alhakim B. , Setyawan Dwi , Ismail Rifky 
Published: July 2017

Produk kaki tiruan atas lutut atau sering disebut sebagai above knee prosthesis (AKP) yang memiliki sendi lutut tiruan berbasis kinerja mekanis masih didominasi oleh produk impor. Produk AKP domestik masih berkonsentrasi pada sistem sendi konvensional. Untuk pasar AKP dengan segmen menengah ke atas yang menghendaki fleksibilitas gerak, kenyamanan, fungsi kaki yang optimal dan kemudahan pengaturan, masyarakat Indonesia masih tergantung terhadap produk impor. Penelitian ini bertujuan untuk melakukan analisis kinematika pada suatu prototipe AKP yang difokuskan pada bagian transfemoral prosthetic dengan sendi mekanis untuk substitusi produk impor. Bagian transfemoral prosthetic pada prototipe AKP yang dibahas adalah jenis four-bar linkage. Analisis yang digunakan adalah hubungan antara dimensi four-bar linkage selama satu siklus gait cycle orang berjalan normal. Siklus gait cycle ini berpengaruh terhadap besarnya sudut yang terbentuk antara sumbu knee ankle (KA) dengan sumbu trocenter knee (TK). Sesuai dengan fungsi AKP, maka penting untuk mendapatkan data teknis tentang hubungan dimensi four-bar linkage pada transfemoral prosthetic. Hasil analisis gerak selama satu siklus gait cycle orang berjalan normal menunjukkan dimensi four bar linkage adalah a = 10 mm, b = 34 mm, c = 15 mm, d = 30 mm, e = 28 mm dan f = 46 mm.
Pengaruh Penggunaan Alat Peraga Statika Terhadap Pemahaman Mahasiswa pada Mata Kuliah Mekanika Statika Struktur
Authors: Satrijo Djoeli , Fitrianto Fatih 
Published: July 2017

Dalam suatu pembelajaran konsep yang bersifat abstrak, seorang dosen memerlukan alat bantu ajar berupa benda – benda konkret sebagai visualisasinya yang disebut sebagai alat peragasederhana. Penelitian ini dilakukan untuk mendeskripsikan pengaruh penggunaan alat peraga sederhana statika sebagai media pembelajaran pada mata kuliah mekanika statikastruktur terhadap prestasi belajar mahasiswa tahun pertama di Departemen Teknik Mesin Undip. Metodologi penelitian yang digunakan adalah penelitian eksperimental (One Group Pre Test Post Test Design) dengan kegiatan pembelajaran yang digunakan tiga kali replikasi. Berdasarkan hasil perhitungan uji-t sesuai dengan hasil nilai rata-rata post test mahasiswa diperoleh thitung untuk kelompok kontrol-eksperimen 1 sebesar 8,54; kelompok kontrol-eksperimen 2 sebesar 3,13; dan kelompok kontrol-eksperimen 3 sebesar 9,64, sedangkan dari ttabel dengan taraf signifikansi 5% diperoleh masing-masing kelompok secara berturut-turut sebesar 1,98; 1,98; dan 1,98. Dari hasil uji-t tersebut menunjukkan bahwa thitung lebih besar daripada ttabel. Hal ini menunjukkan bahwa prestasi belajar kelompok mahasiswa yang menggunakan alat peraga sederhana statika yaitu kelas eksperimen lebih baik daripada kelas kontrol yang tidak menggunakan alat peraga sederhana statika. Sedangkan dari nilai rata-rata post test mahasiswa untuk kelas kontrol sebesar 70 dan untuk kelas eksperimen 1, 2, dan 3 berturutturut sebesar 87; 77; 88. Dari analisis angket respons mahasiswa terhadap pembelajaran dengan menggunakan alat peraga sederhana statika adalah 80% siswa setuju dengan penggunaan alat peraga sederhana statika penyampaian materi lebih jelas dan 80% mahasiswa menyatakan lebih senang dan antusias dalam mengikuti pembelajaran dengan menggunakan alat peraga sederhana statika. Maka dari hasil penelitian tersebut dapat disimpulkan bahwa penggunaan alat peraga sederhana statika berpengaruh terhadap prestasi belajar mahasiswa.
Comparación de los resultados en la resolución de ambigüedades para una red de estaciones GNSS en Europa con el uso de datos GPS y la combinación con datos GLONASS, utilizando el programa de procesamiento Bernese
Authors: Paniagua-Jiménez Diana , Valverde-Calderón Jose 
Published: July 2017

Los parámetros de la ambigüedad en las ecuaciones de observación originales son números enteros. Técnicamente son necesarios dos pasos para fijar las ambigüedades: primero, los parámetros son estimados como valores reales; en el segundo paso se fijan a números enteros. La fijación de las ambigüedades disminuye el número de parámetros a estimar en el ajuste final, lo cual lleva a un ahorro en número de elementos que se almacena en la memoria, en el tiempo invertido en el procesamiento y una mejora en la calidad del cálculo de las coordenadas. Se efectuó la comparación entre los resultados de dos procesamientos de la misma red: en el primero, se procesaron solo observaciones GPS; en el segundo cálculo, se procesaron de forma conjunta observaciones GPS y GLONASS. La red usada en el proyecto está conformada por 25 estaciones GNSS, ubicadas en Europa. El procesamiento se efectuó con el programa Bernese 5.2. Se concluyó que la selección de la estrategia para fijar ambigüedades es un aspecto que debe analizarse detenidamente, debido al impacto que tiene el método de cálculo seleccionado sobre los resultados finales y el tiempo de procesamiento requerido.
Proporción sexual, relación talla-peso y distribución geográfico-batimétrica de Squalus cubensis (SQUALIFORMES: SQUALIDAE) en la costa Caribe de Centroamérica
Authors: Benavides-Morera Rosario , Brenes-Rodríguez Carlos Luis , Márquez-Artavia Amaru 
Published: July 2017

Se describe la distribución geográfica y batimétrica de Squalus cubensis capturados a bordo del B/O Miguel Oliver en la costa Caribe de Centroamérica, durante una campaña de prospección pesquera realizada del 3 de enero hasta el 3 de febrero del 2011. Se analizaron 96 lances, se capturaron 140 individuos (65 machos y 75 hembras) de 24 hasta 100 cm de longitud total, y entre 70 y 3 040 grs de peso total. En cuanto a la talla, se encontró una marcada diferencia que indica dimorfismo sexual. La relación talla-peso para ambos sexos no presentó diferencias significativas en las pendientes de las regresiones entre sexos. La distribución espacial de las capturas mostró que la mayor cantidad de individuos se obtuvo, principalmente, en Panamá a profundidades que van desde los 250 hasta los 950 m, seguido por Honduras. Más del 75% de las capturas se dieron en un estrato de la columna de agua con temperaturas entre los 17°C y los 12°C. El presente trabajo proporciona información preliminar importante, pues es la primera vez que se documenta una captura de esta especie que permita estimar proporción de sexos, estructuras de tallas y la relación peso–talla de S. cubensis en el Caribe de Centroamérica.
Evidências em relação aos riscos à saúde pelo uso do plástico em embalagens alimentícias
Authors: Azeredo Danielle Gaspary de , Gass Vanessa Laís , Milanez José Francisco Bernardes , Pizzato Alessandra Campani 
Published: July 2017

Objetivo: Descrever as evidências relacionadas aos riscos à saúde causados pelo uso de plásticos em embalagens alimentícias.Materiais e Métodos: Foi realizada uma pesquisa exploratória do tipo revisão bibliográfica nas bases de dados PubMed, Embase, Bireme e Lilacs, nos últimos cinco anos. Realizou-se um cruzamento com os termos indexados: “estrogens” AND “plastics”, sendo também utilizado seus respectivos sinônimos. Os dados foram analisados segundo Gil através de quatro leituras: exploratória, seletiva, analítica e interpretativa.Resultados: Dos 192 artigos identificados nas bases de dados (PubMed 134, Embase 58, Lilacs e Bireme 0), apenas dezoito artigos estavam de acordo com os critérios de inclusão. Pela análise interpretativa, estes foram organizados em três categorias e subcategorias: 1 Evidências relacionadas a desordens na saúde de humanos (1.1 Sistema Cardiovascular; 1.2 Sistema Urinário); 2 Evidências relacionadas a desordens na saúde dos animais (2.1 Sistema Cardiovascular; 2.2 Sistema Endócrino; 2.3 Sistema Reprodutor; 2.4 Metabolismo de vitaminas e minerais; 2.5 Ação no código genético); 3 Evidências em materiais plásticos (3.1 Sistema Endócrino; 3.2 Ação no código genético).Conclusão: A maioria dos estudos aponta para riscos à saúde relacionados ao uso de plástico em embalagens alimentícias, especificamente aqueles contendo bisfenol A ou ftalatos em sua composição. As evidências estão relacionadas a desordens nos sistemas cardiovascular, urinário, endócrino, reprodutor, bem como no metabolismo de vitaminas e minerais e ação no código genético.
Adesão a terapia antiretroviral de crianças e adolescentes vivendo com HIV
Authors: Beck Sandra Trevisan , Vielmo Laura , Castro Carolina Quintana , Lubini Angélica Rosa , Zankoski Marina , De Oliveira Juliana Dos Santos 
Published: July 2017

Objetivo: Descrever a adesão de crianças e adolescentes à terapia antirretroviral (TARV) para HIV atendidos em Unidade dispensadora de medicamentos de um hospital público situado na região central do Rio Grande do Sul.Materiais e Métodos: A adesão a TARV foi estratificada em três níveis: alta, regular e baixa adesão, de acordo com a frequência de retirada de medicamentos durante tratamento de 66 pacientes menores de 18 anos, que receberam a forma farmacêutica líquida ou sólida, no período de janeiro a dezembro de 2015. Foi verificada a idade, forma de infecção, cuidador responsável e nível da carga viral ao final do período. Os dados foram obtidos através dos registros do sistema de controle e logística de medicamentos e prontuários clínicos. Utilizou-se estatística descritiva e o estudo foi aprovado (CAAE 47638515.3.0000.5346).Resultados: A média de idade foi de 12 anos. Os pais (77%) são os principais cuidadores responsáveis pelo tratamento. Entre os pacientes que fizeram uso da TARV na forma sólida 36% apresentaram alta adesão, 36% foram considerados com adesão regular e 28% baixa adesão ao tratamento. Apenas 46% mantiveram a carga viral em nível indetectável. Entre os 16 pacientes recebendo a forma farmacêutica líquida 56,2% apresentaram alta adesão, 31,3% adesão regular e 12,5% baixa adesão, sendo que 87,5% apresentaram níveis da última carga viral do período estudado em valores indetectáveis.Conclusão: A adesão à TARV é melhor entre crianças que entre adolescentes, sendo necessário acompanhamento direto para cumprimento da ingestão diária dos medicamentos, com maior comprometimento e conscientização dos cuidadores.
“Let Your Secrets Sing Out”: An Auto-ethnographic Analysis on How Music Can Afford Recovery from Child Abuse
Authors: Lewis Georgina 
Published: July 2017

There is extensive literature documenting that music can enable recovery and healing through various means such as performance and memory-work. However, an understanding of ‘how’ music achieves this is less clear. A combination of academic enquiry and reflective writing from a survivor who uses music to recover offers a compelling perspective on music’s functions and abilities. This article explores how music affords recovery following the chronological timeline of an abuse survivor’s own recovery, and this chronology is presented through four main phases. As a communication device, music can initiate disclosures and expression of trauma. Music can also ground a survivor into the present and thus allow recovery to be manageable. Music can create a safe space through its various qualities; crucially – the musical use of boundaries and in this space recovery can occur. Finally, music can afford the development and maintenance of safe attachments and an understanding of worth, fostering healing from the damage inflicted from abuse. These themes together provide a unique perspective and understanding of how music can afford recovery.
Assessment of behavioral characteristics of patients with depressive disorder variables in psychiatric unit in sulaimani general hospital
Authors: Jassim Arazo 
Published: July 2017

The objective of the study is to assessing the behavioral characteristics of patients with
depressive Disorder. A descriptive study was conducted with the aim of the study. To obtain
reliable and valid data, a questionnaire was developed according to the objectives of the
study. A questionnaire consists of 2 parts, each of which aimed at collecting information and
data as follows, part(I): general information concerning patient's socio-demographical
characteristics, part (II): A list of 40 items describing expected behavioral characteristics in
seven aspects. A purposive sample is used which consists of (50) in-patients in psychiatric
unit in sulaimani general hospital. The patients and their relatives were interviewed for data
collection procedure. The empirical field work was carried out. Descriptive and inferential
statistical methods were used in the analysis of the results using mean and SD to describe
behavioral characteristics. The findings revealed that the most depressive patients with the
age around 35.5 years, mostly female (68%), married (58%), un employed (68%) and have
low level of education, as 42% of them have basic education and 36% illiterate. In addition,
the findings revealed that high mean score of 12 behavioral characteristics are identified by
aspects, in negative self-concept, three behaviors are identified: "patients feel not respected
by other" (M=1.84), "where no good qualities" (M=1.54) and" have no self worth"
(M=1.50). In social detachment the behavior is "I prefer to sit alone" (M=1.66). In passivity
"I feel I am pushed by others to actions when I am not ready" (M=1.560). In somatic
complaint, the patient behaviors that have their " appetite (M=2.92), sleep (M=2.88), weight
(M=2.66) are not increased. In depressive verbal content "I believe that life is nothing" and
"I wish I could get rid of my life" M=1.50 and Abnormal traits "patients believe that people
are unfair in interacting with them" (M=1.60).
Surgical management of Basal cell carcinomas (BCC) of the Head and Neck
Authors: Tawfique Saleh 
Published: July 2017

Ninety six consecutive cases of BCC of the face and head and neck were managed
during 8 years. 51 patients were female and the rest were male. The average age of
presentation was 64Years. The size of majority of lesions (85%) were less than 10mm.
Lesions appeared mainly on mid face around the nose, inner canthus and forehead. 10.5%
had multiple lesions on presentation. All lesions were managed surgically by total excision
of the lesions with 5mm free healthy skin margin and the defect reconstructed
simultaneously by various types of local or distant skin flaps. The effectiveness of this
procedure was 94% cure rate. The average follow up was 2 years (9-36 months). Ten
patients(10.4%) required second surgical resection as they developed recurrence at the
site of primary resection. Eleven patients (11.4%) showed another lesion on the face
during follow up period. Surgical resection and primary reconstruction of BCCs of the
head and neck are highly recommended and give good success and high percentage
(around 94%) of cure rate. Long term follow up is recommended as new lesions or
recurrence may appear years after management.
Numerical Groundwater Flow Modeling for The Intwrgranular Aquifer in Sarsian Sub-Basin, Dokan Lake, Iraqi Kurdistan Region
Authors: Ali Salahalddin , Salley Sardar 
Published: July 2017

Sarsian sub-basin is located in the northeastern part of Iraq and to the northwest of
Sulaimani governorate, north of Dokan dam between Northing (3987401–4006440) and
Easting (498677–506055), covering an area of 99 km2. It is located within the Dokan
reservoir catchment area. It extends on the left bank of the reservoir along the distance of
19 Km. The main aquifers in the studied area are integranular Quaternary aquifer and
karstic to karstic fissured aquifer of Qamchuqa and part of Sarmord. Based on the
analysis of the available water points, it was found that the general groundwater
movement is from northeast to southwest, with two different directions; one unconfined
and the other confined aquifer. Based on the well tests performed on 14 wells that
penetrate the Quaternary aquifer, it was found that the hydraulic conductivity to be with
median value of 3.445 m/d, transmissivity with median value of 382.95 m2/day and specific
yield with median value of 0.1. Groundwater flow simulation was performed for the north
part of Sarsian Sub-basin in both steady and transient states. The steady-state simulation
is based on lower groundwater level (October 2009). A qualitative analysis of the map
indicates that the simulated and the observed piezometric contours display the same
pattern. The hydraulic gradients obtained from the simulated piezometry are similar to
those of the observed piezometry in the whole study area. The model was run for four
future scenarios of groundwater level. The first scenario of Dokan lake stage was
simulated, and three stress periods of transient simulated with different volume of
extraction per day. From the results, it is obvious that Dokan Lake stage has significant
influence on the head fluctuations in the area.
Karst cavity detection in carbonate rocks by integration of high resolution geophysical methods
Authors: Aziz Bakhtiar , Ali Peshawa 
Published: July 2017

Combined surveys using Ground Penetrating Radar (GPR) and Electrical Resistivity
Tomography (ERT) are deployed to provide a cost effective characterization of the
subsurface karst environments. A total of 12 GPR traverses and 4 ERT lines with lengths
from 140 to 710 m are conducted at Sulaimani governorate, NE Iraq (45o 04' E and 35o 35'
N). The area represents a broad syncline of limestone rocks, which is covered by a thin
layer of recent sediments. Great anomaly depicting crest (high) like pattern was noticed on
GPR records. A plausible interpretation for this anomaly was a cavity filled either by
groundwater or by residual products of karstification. The presence of this cavity was
confirmed also by electrical resistivity tomography. An excellent correlation exists
between GPR signatures and ERT layers. The extension and the depth to the top of the
cavity were determined from both GPR data and 2D inversion interpretation. A huge cave
was discovered. It is located at depth of 25.0 meters. It has an elongated shape that extends
from southeast to northwest direction. The geophysical survey results show this cave with
approximate dimensions of 150.0 m long, 35.0 m wide and 24.0 m high.