bluuebunny/crossref_metadata_2025_split huggingface dataset:
Системно-структурный анализ теорий психологических трансформаций личности
Authors: Abakumova Irina V. , Ryadinskaya Evgeniya N. , Golubova Vera М. 
Published: April 2017

The paper presents a systematic and structural analysis of the theories of psychological transformations of personality revealing the main methodological approaches to studying personality changes. Transformations of the person’s sense-value sphere are of special interest.
The study (a) analyses the psychological definitions of the “transformation” concept; (b) provides an overview of various theories and approaches to studying personality and its transformations; (c) reveals dynamic and static theories of personality, as well as theories of development and transformation; (d) describes in detail a psycho-transformational approach; (e) highlights artificial and natural transformations.
The paper considers various models and forms of personal transformation and also presents a “field theory”, which is based on the concepts of “analyzing tendencies” or “forces” creating barriers or promoting transformations, and a “theory of dissatisfaction crystallization", which forms associative relations between subjective perception of problems, expenditure, and negative results.
The considered approaches are classified according the following parameters: principles of development, influence of a situation and the context of activity, types of cognitive activity, and mechanisms of resistance to any changes.
The analysis of the considered approaches and models shows that the level of studying personality determines potentialities of its transformation. Personality changes from the standpoint of functioning levels determine the transformation processes specific to each of them. Fast-paced transformations of personality are characteristic for the sense level.
The systemic and structural analysis of the theories of psychological transformations of personality suggests differentiating possible personality changes at the level of personal activity, personal traits, and at the sense level. Future work will involve studying cognitive, affective, and behavioral transformations of a person in the zone of armed conflict.
Профессиональная мотивация и уровень эмоционального выгорания у пилотов гражданской авиации
Authors: Lyukshina Dar'ya S. , Yurchenko Kseniya А. , Kapustina Tat'yana V. , Kopenko Mariya А. , Potrebich Yuliya G. 
Published: April 2017

The paper provides the results of the empirical study of professional motivation and the level of emotional burnout among flight crew members of Vladivostok international airport. The study involved 40 civil aviation pilots aged 30–45 years having more than 5 years of work experience. K. Zamfir’s “Motivation of professional activity” technique (A. Rean’s modification) and the questionnaire for assessing motivational potential were used for studying professional motivation. The level of emotional burnout was measured using the Maslach Burnout Inventory (MBI) in N. E. Vodop'yanova’s modification and V. V. Boyko’s “Diagnostics of the level of emotional burnout” technique (E. P. Ilyin’s modification).The study findings suggest that the civil aviation pilots (a) were interested in the process of their professional activities, (b) tried to be a part of the staff and to build friendly relationship with colleagues, and (c) had a prevailing intrinsic professional motivation.The study showed that most pilots (n = 22) had an average level of emotional burnout. Moreover, the data revealed (a) stress and fatigue, (b) decrease in professional effectiveness, (c) cognitive decline, (d) avoidance as a defense mechanism, and (e) refusing problem solving. A third of the respondents had a high level of emotional burnout. These respondents noted physical and emotional fatigue, exhaustion of personal resources, feelings of hopelessness and helplessness, and somatic disorders (loss of appetite, headaches, and disturbances of sleep and wakefulness). A fifth of the pilots had a low level of emotional burnout. This finding suggests that these respondents are well-adjusted to their professional activities; they are selfcritical and frank. Besides, increasing the rates of emotional burnout did not change the orientation of motivation (from intrinsic to extrinsic).
Диалогизация и межпредметная интеграция содержания образовательного процесса как факторы развития одаренности школьника
Authors: Dyshlyuk Irina S. , Kameneva Irina Yu. , Moskalenko Anna Е. 
Published: April 2017

Giftedness is an integral feature of personality. The paper deals with the problem of the development of giftedness in mass education without isolating a gifted child from the natural microenvironment. Pedagogical activities should be carried out in the context of schoolchildren’s personal development. To develop schoolchildren’s giftedness, the learning content should be active, conceptual, problem, and personal-sense, as well as include schoolchildren’s personal experience. Dialogisation and interdisciplinary integration are ways for constructing a content of that type. Dialogisation of the learning content brings it to a personal-sense level, increases its problem and conceptual characteristics. In personality-oriented education schoolchildren solve learning tasks as vital. These tasks (a) do not have one correct solution, (b) attract schoolchildren’s interest, and (c) increase their academic motivation.The components entering into a dialogue construct the dialogue content. Hence, activity is inherent in it. The components representing the content of various subjects or subject areas can be a powerful educational force. The integrated content intensifies the subject content, imparts personal sense to certain disciplines, enables gifted children to use and develop their flexibility, metaphoricalness, and associative thinking. The integrated content promotes the development of system and conceptual thinking. A sufficient level of conceptual thinking is necessary for forming interdisciplinary concepts.Dialogisation and integration of the learning content are especially important for the acquisition of interdisciplinary intellectual tools and the development of metasubject abilities. These processes are urgent objectives in modern Russian schools.
Особенности технологий реализации диалога-переживания в практике образовательного процесса
Authors: Rudakova Irina А. , Miroshnichenko Tat'yana V. 
Published: April 2017

Elaborating the dialogue-experience techniques in the educational process relied on the following: (a) revealing the role of sense experiences in sense accumulation processes, as well as their comparison and generating new senses, conditioned by learners’ need for understanding themselves and other people; (b) studying personalization and personification, personal ways of their implementation (in images, sense constructs and dispositions, as well as in orientation); (c) clarifying the role of emotional and empathic, figurative, and reflective experiences which provide sense harmonization of dialogue participants’ sense stands when forming the joint relation to educational activities; (d) studying the role of the coordination of these experiences in forming interpersonal relationships in educational activities, as well as the transformation of sense structures in inter-group interaction when performing co-creative activities through the phenomena of “reflected subjectivity” (the image of Another, the image of significant Another, and the personified image of significant Another).In accordance with the features of learners’ emotional and empathic, figurative, and reflective experiences, the analysis highlighted and described the generalized techniques. These techniques fell into three blocks determining the direction of psychological, psycho-pedagogical, and pedagogical support of learners in the educational process. Each block included the following three groups of more particular techniques: (a) lowering negative experiences, restoring “missing” experiences, and forming positive experiences (the psychological block of techniques); (b) personified education, techniques of team building, and reflective techniques (the psychopedagogical block of techniques); techniques for solving the issues of sociability, co-creation, and cooperation in co-creative activities (the pedagogical block of techniques).The developed dialogue-experience techniques can “turn” the learner to Another and enable the teacher to manage the educational process in a “soft” manner.
CRITICAL REVIEW OF PHARMACOGENOMICS IN ANTIPARKINSONIAN DRUG THERAPY: IMPACT ON CLINICAL MANAGEMENT OF PARKINSON’S DISEASE
Authors: R Poornima , Bashir Sabreen 
Published: April 2017

Parkinson’s disease is a progressive neurodegenerative disorder characterized by rest tremors, bradykinesia , rigidity , postural instability , gait dysfunction and several non motor symptoms . The marked difference in drug response and adverse effect profile among patients led to search of genetic markers and polymorphism associated with response to antiparkinsonian drugs which will enable us to predict an individuals response to drugs in terms of both efficacy and toxicity. Hence efforts to define the role of genetic polymorphism in optimizing pharmacotherapy of Parkinson’s disease have been undertaken and some promising genetic loci for the treatment have been determined. Therefore we aim to present a critical review of pharmacogenetic aspects of levodopa , dopamine agonists and COMT inhibitors and describe gene polymorphism of interest for future research.
ANREDERA CORDIFOLIA LEAVES FRACTION AS AN ANTI-HYPERLIPIDEMIA
Authors: Lestari Dwintha 
Published: April 2017

Objective: The objective of this research was to evaluate reduction of blood cholesterol level by fraction extracts of binahong (Anredera cordifolia) on male Wistar rats. Methods: The rats were given high fat food every day for 3 months and pure cholesterol on week 0, 3, 7 and 11. After that each binahong fraction (n-hexane fraction, ethyl acetate fraction and water fraction) with doses of 50 mg/kg bw, 100 mg/kg bw, 200 mg/kg bw were given orally for 3 weeks and observed for lipid profile on day 21. Results: The result showed that n-hexane, ethyl acetate and water fractions of binahong leaves decreased total cholesterol, triglyceride and LDL level, and did not influence the HDL level. Meanwhile statin decreased total cholesterol, triglyceride and LDL level, and increased HDL level. Conclusion: Ethyl acetate fraction of binahong leaves significantly reduced total cholesterol level, triglycerides, LDL level compared to negative control group (p< 0.05) and had no influence in HDL level. Keywords: Atherosclerosis, Anredera cordifolia, cholesterol
Investigation of phytochemical composition, evaluation of antioxidant, antibacterial activities and toxicity study of Emblica officinalis and Terminalia bellirica fruits
Authors: Badoni Himani , Singh Saumya , Sharma Promila , Waheed Syed Mohsin 
Published: April 2017

The present study deals with exploration of various beneficial potential of Emblica officinalis and Terminalia bellirica fruit extracts which includes phytochemical analysis and evaluation of total phenolics content (TPC), total flavonoids content (TFC) and antimicrobial activity. The antioxidant activity of the extracts was examined using diphenylpicrylhydrazyl (DPPH), TPC and TFC assay. The antimicrobial activity of the extracts was evaluated by agar well diffusion assay. Although, the extracts prevented the growth of both Gram positive and Gram negative bacteria. The EOA and EOM extracts both exhibit tannins, saponins, phenols and carbohydrates whereas, alkaloids and flavonoids are found only in EOM, and glycosides showed their presence in aqueous extract only. In contrast, TBA and TBM extracts, both contains alkaloids, tannins, coumarins, flavonoids and phenols. While carbohydrates are present barely in TBM, and TBA extract showed the presence of saponins and glycosides. The TPC results show that EOM (528±.013) has highest phenolic content in it followed by EOA (509±.003), TBM (284±.06) and TBA (280±.036). In TFC analysis too EOM (154±0) showed a higher concentration range of flavonoids followed by EOA (142±0),TBM (126±.017) and TBA (119±.007). In DPPH scavenging assay EOM (86.88±.310) showed maximum % inhibition followed by EOA (85.32±.414), TBM (80.57±.569) and TBA (75.55±.362) respectively. Antibacterial assay showed varying results for different bacterial strains such as, for EOA (10±1) demonstrated highest inhibition against E. coli, EOM (11.5±0.5) exhibited maximum inhibition against S. aureus, for K. pneumoniae EOA (13±2) displayed maximum inhibition and in case P. aeruginosa too EOA (12.5±0.5) showed maximum inhibition while TBM and TBA too showed significant amount of inhibition against test bacterial strains. The antibacterial and antioxidant activities of the extracts were found to be positively associated with the total phenolic and flavonoid content of the extracts. This study was conducted to identify the phytochemical composition of the fruit extracts of the two plants, their antioxidant and antibacterial potential, alongwith their neuroprotective and nootropic role. In order to establish their neuroprotective role, acute toxicity study was conducted on wistar rats to establish the safety of the extracts. The current study demonstrates and compares the antioxidant, antibacterial activities of the fruit extracts of Terminalia bellirica and Emblica officinalis and acute toxicity study further demonstrates that the extracts used are safe to conduct neuroprotective studies. Keywords: TPC(Total phenolic content), TFC(Total flavonoids content), EOM (Emblica officinalis Methanolic fruit extract), EOA(Emblica officinalis aqueous fruit extract) TBM (Terminalia bellirica Methanolic fruit extract) and TBA (Terminalia bellirica aqueous fruit extract).
THE GREEN SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL EFFICACY OF SILVER&GOLD NANOSPHERES SYNTHESIZED FROM WHEAT BRAN
Authors: Gupta Sonika 
Published: April 2017

AbstractIn the present scenario, biogenic production of gold and silver nanoparticles has evoked considerable interest in terms of their diverse biomedi0058cal applications because of their extremely small size and large surface to volume ratio. Hence, the aims of the current study were to use plant extract for the biosynthesis of silver and gold nanoparticles and to evaluate their antibacterial and antioxidant activity in vitro. First, aqueous silver nitrate and chloroauric acid solutions have been treated with Wheat bran extract;reduction of the silver and chloroaurate ions is witnessed resulting in the formation of highly stable silver and gold nanoparticles in solution. Characterization of synthesized silver and gold nanospheres is made using UV-visible,SEMandTEManalysis, indicated that they ranged from 30 to 55 nm and 45 to 70 nm in size respectively. The free radical scavenging potential has been investigated using DPPH assay, examined by a UV-visible spectrophotometer and found that AgNPs AuNPs exhibited exceptional potential- compared to wheat bran extract alone. Antimicrobial efficacy against dental disease causing pathogens - Staphylococcus aureus (MTCC 7443) and Streptococcus mutans (MTCC 497) was tested using agar diffusion method. The synthesized AgNPs and AuNPs efficiently inhibited the growth of respective pathogens. It could be concluded that these nanospheres can be act as potent antioxidant and antimicrobial agents for commercial application. Keywords: AgNPS, AuNPS, Wheat Bran, DPPH Scavenging Assay, Antioxidant Activity, Antimicrobial Activity, SEM, TEM
Management of pain using transdermal patches
Authors: Mathews Leya Meriam 
Published: April 2017

Transdermal delivery is a non-invasive route of drug administration through the skin surface that can deliver the drug at a predetermined rate across the dermis to achieve a local or systemic effect. It is potentially used as an alternative to oral route of drugs and hypodermic injections. Analgesics are mostly used for various diseases as most of them are associated with severe or mild pain .The use of analgesics as a pain relief patch is now being used commonly. A transdermal analgesic or pain relief patch is a medicated adhesive patch used to relieve minor to severe pain. Currently, the patches are available for many Opioids , Non opioids analgesics. Local anesthetics and antianginal drugs. The drugs include Fentanyl, Buprenorphine ketoprofen, diclofenacepolamine , piroxicam , Capsaicin ,Nitroglycerine and Lignocaine . They are available as both matrix and reservoir patches. This review explores the various drugs used to manage pain and their route of administration in terms of frequency, complications and effects
INVESTIGATION OF Helicobacter pylori VIRULENCE GENOTYPE IN GASTRIC BIOPSIES BY PCR
Authors: Al-jelawi- Rabab Omran 
Published: April 2017

Background: Helicobacter pylori infections has been associated with the genetic diversity of their virulence factors, the virulence genotypes are valuable as molecular marker in the diagnosis of patients with bacterial infections . Our main objective was to analyze the frequency and allelic genotype of vacA , cagA also investigate another virulence genes of H. pylori. Methods: 75 biopsies of patients with gastritis and peptic ulcer diseases were selected to investigate the presences of H. pylori and collected from them antrum biopsies, then genomic DNA was extracted from antrum biopsies using genomic DNA kit .Subsequently, the virulence genes of H. pylori were amplified using specific primers including vacA , cagA, cagE and oipA and iceA by PCR in 49 cases that positive to 16SrRNA which previously investigated. Results: A high prevalence of genes cagA (28.6%), vacAs1bm2 (56.8%), iceA2 (30.6%) and oipA (42.9%) was found, while vacA s2m1 and iceA1 genotypes was not found in our study. There was significant correlation between the presence of cagA and cagE genotypes (p = 0.02), suggesting that these two genes almost used together as cag PAI integrity marker. The presence of cagA gene was significantly associated with peptic ulceration (p ≤ 0.001), whereas different vacA genotypes or iceA2 genotype were no statistically significant with clinical outcome. Patients with peptic ulcer disease more likely to have oipA gene (61.9% ) than those with gastritis (38.1%), P = 0.037, also the presence oipA gene was statistically significant with presence iceA2. Conclusion : Most H. pylori genotypes which associated with peptic ulcer and gastritis were moderate virulent strains.
PHYTOCHEMICAL COMPOSITION AND ANTICANCER ACTIVITY OF SEAWEEDS ULVA LACTUCA AND EUCHEUMA COTTONII AGAINST BREAST MCF-7 AND COLON HCT-116 CELLS
Authors: Arsianti Ade Arsianti , Fadilah Fadilah , Suid Kusmardi , Yazid Fatmawaty , Wibisono Lies Kurniati , Azizah Norma Nur , Putrianingsih Rista , Murniasih Tutik , Rasyid Abdullah , Pangestuti Ratih 
Published: April 2017

Objective: this study is aimed to develop marine resources which is focused on the determination of phytochemical composition and exploration of seaweeds Ulva Lactuca and Eucheuma cotonii, as a potential anti-breast cancer and anti-colorectal cancer agents. Methods: Seaweeds Ulva Lactuca collected from Parangtritis beach, Yogyakarta, Central Java, Indonesia. Whereas Eucheuma cottonii collected from Salemo island, South Sulawesi, Indonesia. Seaweeds U. lactuca and E. cottonii were macerated in organic solvents, n-hexane, chloroform, ethyl acetate and ethanol, respectively. After maceration for three days, the mixture was filtered, the filtrate was concentrated by rotary evaporator. The concentrated extract of n-hexane, ethyl acetate, ethanol and chloroform were then analyzed by thin layer chromatography. Phytochemical test of the concentrated extract were conducted to identify the metabolites containing in the seaweeds. Furthermore, the cytotoxic activity of the n-hexane, ethyl acetate, ethanol and chloroform extract of Ulva Lactuca and Eucheuma cotonii were evaluated as a growth inhibitor of breast MCF-7 and colorectal HCT-116 cancer cells by MTT cell proliferation assay. Results: Phytochemical test for the concentrated extracts of Ulva Lactuca showed the positive result for metabolites of steroids, glycosides, flavonoid,and tannin. While the concentrated extracts of E. cottonii showed positive result for metabolites of steroids, glycosides, and flavonoid. Both concentrated extracts of Ulva lactuca and Eucheuma cotonii exhibited anticancer activity against breast MCF-7 and colorectal HCT-116 cells with IC50 ranging of 21 µg/mL to 99 µg/mL . Conclusion: Our results clearly demonstrate seaweeds Ulva Lactuca and Eucheuma cotonii as a promising candidates for the new anti-breast and anti-colorectal cancer agents. Keywords: Phytochemistry, Ulva Lactuca, Eucheuma cotonii , anticancer, breast MCF-7, colorectal HCT-116
Role of environmental factors on sleep patterns of different age groups
Authors: Rj Ilankizhai , R Gayatri Devi 
Published: April 2017

ABSTRACT OBJECTIVE :The objective of the study is to determine the effect of various environmental factors associated with modern lifestyle,on sleep patterns of three different age groups through a survey based study. METHODSThis was a survey based cross sectional study. A questionnaire which included questions about their lifestyle habits such as caffeine consumption, electronic media or gadget usage, bedtime and wake up time were distributed to people of different ages who were grouped into three age groups. The data collected was then analyzed statistically. RESULTSMost of the habits of today's sedentary lifestyle such as excessive stimulant consumption and extensive late night usage of electronic media and gadgets have a negative impact on both quality and quantity of sleep. People with such habits tend to have a very short and disturbed sleep. From the current study, it is clearly evident that the group which is most affected are the adolescents. CONCLUSIONAwareness regarding the ill effects of these modern day lifestyle factors would help everyone to minimise the adverse effects of these factors on sleep and aid in adopting a healthy lifestyle.
EFFECT OF SARGASSUM ILICIFOLIUM ON OVOGENESIS IN PCOS INDUCED RATS
Authors: Jayaraman Anbu , Jayaraman Anbu , Krishnan Sukanya , Shivalingappa Santhosh Kumar , Reddy Ramya P S , Nandihalli Vani B 
Published: April 2017

Objective: This study was conducted to evaluate the effect of Sargassum ilicifolium (S. ilicifolium) on Testosterone induced Polycystic Ovary Syndrome (PCOS) in rats.Methods: Female Wistar albino rats were divided into 6 groups consisting of 6 rats each. PCOS was induced in all the animals except normal group on administration of Testosterone (2 mg/100 g) for 21 d daily. After PCOS induction the standard group rats were treated with Clomiphene citrate (CC) (1 mg/kg p.o.). The test groups were treated with 100, 200 and 400 mg/kg of ethanolic extract of Sargassum ilicifolium (EESI) orally and normal animals were administered 2% CMC (2 ml/kg) respectively for 21 d. During induction and treatment period various parameters like oestrus cycle, histopathology, hormonal and biochemical assays have been evaluated. Further to confirm the enhanced fertility rate, the rats were mated and the litter size was observed.Results: The results revealed the normalcy in oestrus cycle, hormonal, biochemical and histopathological parameters. The litter size was increased significantly compared to control.Conclusion: Overall, from the obtained results it is determined that the S. ilicifolium exhibited a good anti-androgenic effect by reducing the Testosterone levels in PCOS induced conditions.