bluuebunny/crossref_metadata_2025_split huggingface dataset:
Steric Engineering of HOF Hierarchical Branched Homostructures for 3D Photonic Logic Processing
Authors: Yao Yinan , Wu Qirui , Ren Shizhe , Zhao Yong Sheng , Guan Lunhui 
Published: September 2024

AbstractControlled manipulation of photons/electrons at micro/nanoscale holds the key to the development of versatile optoelectronics devices. However, current photonics devices are primarily constructed from simple low‐dimensional structures, which suffer from limited structural design freedom due to the planar processing scheme, impeding further performance improvement and functionality upgrades. Herein, the first 3D hydrogen‐bonded organic framework (HOF) branched homostructure with spatial positioned multi‐input/output optical channels for 3D photon manipulation is reported. The free‐standing 3D HOF branched homostructures are prepared by a steric engineering strategy, which involves a multinucleation‐assisted growth mechanism. The hierarchical Y‐type and X‐type HOF homostructures exhibit asymmetrical photon transport behaviors, showing applications in optical logic gates with single or dual ON/OFF functionality, respectively. Moreover, the 3D HOF branched homostructure with multiple spatially distributed input/output optical channels displays spatial asymmetric photon transport, which functions as spatial photonic signal logics. These results offer a novel strategy for the development of HOF‐based photonic devices with 3D photon manipulation.
A Novel Metabolomic Aging Clock Predicting Health Outcomes and Its Genetic and Modifiable Factors
Authors: Jia Xueqing , Fan Jiayao , Wu Xucheng , Cao Xingqi , Ma Lina , Abdelrahman Zeinab , Zhao Fei , Zhu Haitao , Bizzarri Daniele , Akker Erik B van den , Slagboom P. Eline , Deelen Joris , Zhou Dan , Liu Zuyun 
Published: September 2024

AbstractExisting metabolomic clocks exhibit deficiencies in capturing the heterogeneous aging rates among individuals with the same chronological age. Yet, the modifiable and non‐modifiable factors in metabolomic aging have not been systematically studied. Here, a new aging measure—MetaboAgeMort—is developed using metabolomic profiles from 239,291 UK Biobank participants for 10‐year all‐cause mortality prediction. The MetaboAgeMort showed significant associations with all‐cause mortality, cause‐specific mortality, and diverse incident diseases. Adding MetaboAgeMort to a conventional risk factors model improved the predictive ability of 10‐year mortality. A total of 99 modifiable factors across seven categories are identified for MetaboAgeMort. Among these, 16 factors representing pulmonary function, body composition, socioeconomic status, dietary quality, smoking status, alcohol intake, and disease status showed quantitatively stronger associations. The genetic analyses revealed 99 genomic risk loci and 271 genes associated with MetaboAgeMort. The tissue‐enrichment analysis showed significant enrichment in liver. While the external validation of the MetaboAgeMort is required, this study illuminates heterogeneous metabolomic aging across the same age, providing avenues for identifying high‐risk individuals, developing anti‐aging therapies, and personalizing interventions, thus promoting healthy aging and longevity.
Population histories of variable reproductive success and low winter precipitation correlate with risk‐averse seed germination in a mediterranean‐climate winter annual
Authors: Vergara Isabella H. , Geber Monica A. , Moeller David A. , Eckhart Vincent M. 
Published: September 2024

AbstractPremiseSeed germination involves risk; post‐germination conditions might not allow survival and reproduction. Variable, stressful environments favor seeds with germination that avoids risk (e.g., germination in conditions predicting success), spreads risk (e.g., dormancy), or escapes risk (e.g., rapid germination). Germination studies often investigate trait correlations with climate features linked to variation in post‐germination reproductive success. Rarely are long‐term records of population reproductive success available.MethodsSupported by demographic and climate monitoring, we analyzed germination in the California winter‐annual Clarkia xantiana subsp. xantiana. Sowing seeds of 10 populations across controlled levels of water potential and temperature, we estimated temperature‐specific base water potential for 20% germination, germination time weighted by water potential above base (hydrotime), and a dormancy index (frequency of viable, ungerminated seeds). Mixed‐effects models analyzed responses to (1) temperature, (2) discrete variation in reproductive success (presence or absence of years with zero seed production by a population), and (3) climate covariates, mean winter precipitation and coefficient of variation (CV) of spring precipitation. For six populations, records enabled analysis with a continuous metric of variable reproduction, the CV of per‐capita reproductive success.ResultsPopulations with more variable reproductive success had higher base water potential and dormancy. Higher base water potential and faster germination occurred at warmer experimental temperatures and in seeds of populations with wetter winters.ConclusionsGeographic variation in seed germination in this species suggests local adaptation to demographic risk and rainfall. High base water potential and dormancy may concentrate germination in years likely to allow reproduction, while spreading risk among years.
Utility of UAS Photogrammetry and Thermal Sensors for Identifying Locations and Understanding Functions of Puebloan Gravel Mulch Fields in Northern New Mexico
Authors: Davis Kaitlyn E. , Klehm Carla E. , Williamson Malcolm 
Published: September 2024

ABSTRACTThis article presents results from an unmanned aircraft system (UAS) aerial remote sensing study to improve understanding of Pueblo agricultural features in the Northern Rio Grande area of New Mexico that were in use by the 13th century ad. It builds on previous archaeological research that has focused on recording precontact and historic Pueblo agricultural practices, pollen analyses and paleoclimatic reconstruction. Evidence suggests that Pueblo people were successfully growing crops including maize, cotton and wheat, in areas where, based on environmental conditions, they could not necessarily grow. This study seeks to better understand the environmental modifications employed by Pueblo peoples to enable growth of these crops. Cobble‐bordered gravel mulch field systems, thought to retain heat and moisture, are located throughout the study area. This article discusses the utility of airborne photogrammetry to locate and map gravel mulch fields on the landscape. Geographic information system (GIS) analysis of the UAS‐derived digital surface model includes slope, aspect and water flow direction and sink to shed light on gravel mulch field function. The article also discusses the potential of handheld and airborne infrared imaging for assessing the thermoregulation of these fields. Final consideration of how the survey results align with the priorities of the Tewa people for future arid‐land farming demonstrates additional utility of the approach.
Robust adaptive fixed‐time stabilization of disturbed planar high‐order nonlinear systems
Authors: Yao Qijia , Ma Li , Li Qing , Wang Heng 
Published: September 2024

AbstractIn this letter, an adaptive fixed‐time integral sliding mode (ISM) controller is exploited for the stabilization of disturbed planar high‐order nonlinear systems. The exploited controller is designed by constructing a novel fixed‐time ISM surface to tackle the high‐order power. Moreover, the parametric adaptive technique is embedded to estimate the square of the upper bound of the disturbance. In this way, the exploited controller has no obvious chattering problem and can maintain the high control accuracy simultaneously. The resultant closed‐loop system is proved to be practically fixed‐time stable through the bilimit homogeneous theory and fixed‐time Lyapunov stability theory. Lastly, two simulated examples are carried out to demonstrate the derived results.
Do tax incentives matter in promoting corporate ESG performance toward sustainable development?
Authors: Zhang Xiaosan , Jiang Qingquan , Cifuentes‐Faura Javier , Hu Xiaojie , Li Yuyan 
Published: September 2024

AbstractEnvironmental, Social, and Governance (ESG) reflects the new concept of global sustainable development. This paper, integrating institutional theory, stakeholder theory, and the resource‐based view (RBV), aims to explain how tax incentives enhance corporate ESG performance. Using listed companies in China as the research sample, this paper employs a two‐way fixed effects model to empirically test the causal relationship between the variables. The empirical results show that tax incentives significantly promote overall corporate ESG performance as well as its individual dimensions. Mechanism analysis reveals that tax incentives enhance ESG performance by improving corporate technological innovation capabilities. Heterogeneity analyses indicate that the positive impact of tax incentives on ESG performance is more pronounced when firms are state‐owned, from nonpolluting industries, and located in the eastern region. Our findings contribute valuable insights to scholars and industry experts researching the impact of fiscal policies on corporate ESG performance.
Decontesting an essentially contested concept: The standardization of sustainable finance
Authors: Boiral Olivier , Brotherton Marie‐Christine , Gilbert‐Parisée David , Talbot David , Martinez Isabelle 
Published: September 2024

AbstractThe aim of this article is to investigate how the standardization process and the public consultations carried out in the development of new sustainable finance standards and laws tend to shape the decontestation of practices in this field. The analysis of 255 comment letters submitted by various stakeholders in the context of these public consultations shows the dual role of standardization as a mechanism for both the decontestation and the (re)contestation of sustainable finance. This article makes important contributions to the emerging literature on the governance of sustainable finance through initiatives that are meant to improve the transparency of disclosures in this field and prevent investor misconduct. In light of Gallie's theory of essentially contested concepts, this article also contributes to the literature on the challenges of developing sustainability standards and the implications of adopting practices centered on concepts whose meanings and applications are the subject of endless disputes.
Tightly Interfaced Cu2O with In2O3 to Promote Hydrogen Evolution in Presence of Biomass‐Derived Alcohols
Authors: Impemba Salvatore , Provinciali Giacomo , Filippi Jonathan , Caporali Stefano , Muzzi Beatrice , Casini Andrea , Caporali Maria 
Published: September 2024

AbstractBy a mild and straightforward synthetic protocol in aqueous solution and without surfactants, hierarchical Cu2O nanospheres were grown on preformed In2O3 nanostructures, varying the ratio In : Cu (2.5, 0.5). Accordingly, two different binary compounds In2O3‐Cu2O were prepared and afterwards they were integrated with TiO2 NPs. The ternary composites having a loading of 2.0, 5.0 and 10.0 wt.% respectively of binary In2O3‐Cu2O, were tested as photocatalysts in the solar‐driven production of hydrogen from water, using as sacrificial agents alcohols derived from the biomass. Satisfyingly, the rate of H2 evolution (20.5 mmol/g h) resulted two orders of magnitude higher respect to bare TiO2 (0.2 mmol/g h). Electrochemical impedance spectroscopy and photoluminescence measurements revealed the formation of a tight heterojunction between In2O3 and Cu2O, which is responsible for the improved charge carrier density and transfer and for the diminished electron‐hole recombination.
Alanine Production by Chemical Upcycling of Polylactic Acid Waste Over Fe‐Doped Ru/CeO2
Authors: Zhao Qiang , Hu Jiaxue , Gui Zhenzheng , Chang Zhiwei , Zhang Chundong , Chen Yuhui , Huang Yong , Zhang Peng , Wang Fenfen 
Published: September 2024

AbstractBiodegradable polyesters, such as polylactic acid (PLA), is one of the most promising plastics with great potential to contribute to enabling a sustainable global circular economy. However, the efficient chemical upcycling of PLA plastic waste into high‐value chemicals remains a grand challenge. Herein, a series of Ru/CeFeOx catalysts with varying Ru loadings were developed for the catalytic amination of PLA plastic waste to alanine in the presence of ammonia. The as‐prepared catalysts exhibited exceptional catalytic activity, high selectivity, and excellent recyclability, achieving an alanine yield of 70.5 % at 180 °C for 18 h, significantly surpassing previous reports. The outstanding catalytic performance can be primarily attributed to the presence of Fe species in Ru/CeFeOx, which generated more oxygen vacancies, provided abundant base sites, and enhanced reducibility, therefore accelerating the reaction rate and enhancing catalytic efficiency. This study presents an alternative strategy for the sustainable chemical upcycling of PLA plastic waste into alanine and the realization of a circular economy.
Bending the rules: A novel approach to laryngeal surgery in a body donor study
Authors: Kienle Linus L. , Schild Leon R. , Boehm Felix , Hahn Viola D. , Greve Jens , von Witzleben Adrian , Hoffmann Thomas K. , Schuler Patrick J. 
Published: September 2024

AbstractBackgroundTransoral laser microsurgery, the standard surgical approach for early‐stage laryngeal cancer, necessitates an unobstructed line of sight to the operating field. However, achieving adequate laryngeal exposure can be challenging, potentially compromising treatment outcomes.MethodsWe developed a 3D‐printed curved laryngoscope (sMAC), designed to match the upper airway anatomy. In a user study (n = 15) with a human body donor we compared the sMAC system to conventional microlaryngoscopy regarding laryngeal exposure and accessibility in a difficult exposure scenario.ResultsAll 15 participants achieved complete glottic exposure and successfully manipulated laryngeal landmarks using the sMAC system. Only four participants achieved partial exposure using microlaryngoscopy. Positioning of the sMAC system was significantly faster (p = 0.023). A vocal cord resection was conducted successfully (n = 2) using the sMAC system.ConclusionThe sMAC system effectively addresses challenges associated with transoral laryngeal surgery. Ongoing development aims to overcome current limitations of the system and prepare first clinical trials.
How Does a Firm's Information Environment Influence CEO Compensation?
Authors: Fan Shihui , Zhou Yan 
Published: September 2024

ABSTRACTThis paper investigates the relationship between firms’ information environment and chief executive officer (CEO) compensation. This study measures firms’ information environment by their internal and external information quality. The internal information quality is proxied by four variables: discretionary accrual, income smoothing ratio, internal control weakness, and restatements. The external information quality is measured by four other variables: analysts following, analysts forecast accuracy, stock liquidity, and bid‐ask spread. We provide three primary results. First, a firm's overall internal and external information quality significantly increases the CEO's total compensation. Second, a higher quality of internal financial information leads to an increase in the CEO bonus. Finally, a greater quality of the external information environment results in a rise in the CEO's equity compensation. Our additional test provides novel evidence that the dual role of compensation and audit committees increases CEO equity compensation. Our study contributes significantly to the literature on the determinants of CEO compensation and the impact of the board of directors on a firm's information quality and management compensation. Our study's findings highlight that overlapping audit and compensation committees can effectively oversee executive compensation practices and monitor the external market environment.
Change from originator infliximab to biosimilar does not affect 1‐year outcome in children with inflammatory bowel disease
Authors: Solomon Viven , Kuzoian Sydney , Michel Genesis , Brimacombe Michael , Hyams Jeffrey S. 
Published: September 2024

AbstractObjectivesPayer mandates have resulted in children with inflammatory bowel disease (IBD) switching from originator Remicade® (O‐Rem) to an infliximab biosimilar (B‐IFX). Patients and families are fearful of switching because disease has been well controlled on O‐Rem. Real‐world data documenting clinical outcomes after such switches in pediatric patients are limited. The aim of this project was to examine 1 year of follow‐up in a large adolescent/young adult IBD cohort who changed from O‐Rem to B‐IFX.MethodsWe identified patients with IBD at Connecticut Children's receiving O‐Rem for at least 1 year, who were either in clinical remission or had low disease activity, and who were subsequently switched to B‐IFX. An age, gender, IBD‐subtype, and duration since diagnosis cohort that continued on O‐Rem was then matched to the switch cohort and served as a comparator group (1: switch vs. 2: no‐switch). B‐IFX was Inflectra® in all cases.ResultsTwo hundred and seventy‐nine patients (mean age 18.7 years, Crohn's disease = 243, ulcerative colitis = 36) were studied (switch, n = 93, no‐switch, n = 186). Mean time since diagnosis was >6 years in both groups, and mean duration of anti‐tumor necrosis factor use was >5 years. There were no significant changes in hemoglobin, albumin, C‐reactive protein, erythrocyte sedimentation rate, or disease activity in either group over 1 year. Dosing modifications as well as the frequency of low‐level antibodies to infliximab were similar in both groups over the study period.ConclusionSwitching from O‐Rem to B‐IFX has no impact on clinical or laboratory parameters over the subsequent year. Clinicians can reliably reassure patients and families that switching is safe.
In Vivo Imaging Techniques for the Human Scalp: A Systematic Review of the Literature
Authors: Hedayati Bobak , Horton Luke , Urso Brittany , Ekelem Chloe , Babadjouni Arash , Sharma Ajay N. , Mesinkovska Natasha Atanaskova 
Published: September 2024

ABSTRACTObjectiveScalp inflammation and alopecia are distressing conditions for which patients regularly present to dermatology. Although some diagnoses can be made clinically, others require biopsy, which carries the risk of pain, infection, bleeding, and scarring. This review examines the existing literature regarding noninvasive in vivo imaging techniques and their evidence and utility in evaluating scalp pathology, with a focus on the diagnostics of hair conditions.MethodsA systematic literature search was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines without timeframe restrictions. The PubMed and Clarivate (Web of Science) databases were searched using the terms (“imaging” OR “in‐vivo imaging” OR “non‐invasive imaging” OR “non‐invasive in vivo imaging” “imaging,” “in‐vivo imaging) AND (“human scalp disorders” OR “scalp” OR “hair loss” OR “alopecia”). Peer‐reviewed randomized control trials (RCTs), prospective studies, retrospective studies, and case series or reports discussing in vivo imaging of the scalp published before 2022 were selected.ResultsForty‐two studies were included and discussed; modalities included laser devices (n = 27), ultrasound (US) (n = 13), infrared thermography (n = 1), skin capacitance imaging (SCI), and ultraviolet light–enhanced visualization (ULEV) (n = 1). The most common laser devices used were reflectance confocal microscopy (RCM), multiphoton microscopy (MPM), and optical coherence tomography (OCT). US techniques included high‐frequency US (HFUS) and US biomicroscopy (UBM).ConclusionQuality imaging of the scalp in the setting of alopecic, neoplastic, and inflammatory diseases is highly sought after. Many of these noninvasive imaging techniques show promise, each with individual advantages and disadvantages in imaging‐specific conditions. Ultimately, noninvasive imaging techniques may be used to optimize patient management and minimize morbidity associated with scalp biopsies.
New Tricyclic Aryl Quinazoline Derivatives by Suzuki‐Miyaura Cross‐Coupling
Authors: Elmuradov Burkhon , Okmanov Rasul , Juraev Bakhromjon , Dräger Gerald , Butenschön Holger 
Published: September 2024

AbstractA number of new deoxyvasicinone (2,3‐dihydropyrrolo[2,1‐b]quinazolin‐9(1H)‐one) and mackinazolinone (6,7,8,9‐tetrahydro‐11H‐pyrido[2,1‐b]quinazolin‐11‐one) derivatives with aryl substituents at C7/C8 and at C5 are reported. These compounds are rare representatives of their kind and were prepared in high yields by Suzuki‐Miyaura cross‐coupling reactions between 7‐bromo‐2,3‐dihydro[2,1‐b]quinazoline‐9‐(1H)‐one, 5,7‐dibromo‐2,3‐dihydro[2,1‐b]quinazoline‐9‐(1H)‐one or 8‐bromomackinazolinone and respective arylboronic acids with palladium acetate as the catalyst. The products were characterized spectroscopically and, in addition, by X‐ray crystal structure analyses in six cases.
Prostate cancer focal therapy: surgeon experience influences oncological results
Authors: Murta Claudio Bovolenta , Júnior José Pontes , de Souza Filho Pedro Humberto Felix , de Godoy Júnior Paulo Cezar , Pugliesi Felipe Guimarães , El Hayek Kayann Reda , Gallucci Fábio Pescarmona , Guglielmetti Giuliano Betoni , de Almeida Claro Joaquim Francisco 
Published: September 2024

AbstractIntroductionCharacterization of the index lesion of prostate cancer (PCa) has facilitated the development of focal therapy to reduce complications caused by radical treatments. In the present study, we sought to identify factors associated with the oncological results of focal therapy for PCa.MethodsBetween April 2017 and February 2020, 123 PCa patients received focal therapy performed with high‐intensity focused ultrasound (HIFU). The patients presented unilateral localized disease, PSA < 20 ng/dl, clinical stage T1–T2, ISUP grade 1–3, and more than 10 years of life expectancy. Five certified surgeons with different levels of experience performed the procedures and were divided into groups #1 and #2 (>30 HIFUs performed) and #3 (10–15 HIFUs performed each). All patients were prospectively followed and underwent surveillance biopsy 1 year post‐treatment. The primary endpoint was radical treatment, and secondary endpoints included focal therapy failure and in‐field recurrence. Univariate and multivariate logistic regression were used to detect associations between clinical and procedure variables and the endpoints.ResultsThe median follow‐up was 54.3 months, with a mean age of 64.4 years. The mean PSA was 6.6 ng/dl; 59.3% of patients had intermediate‐risk disease, and the remaining had low‐risk. During follow‐up, 29 (23.6%) patients required radical treatment (external beam radiation therapy), 37 (30.1%) experienced treatment failure, and 26 (21.1%) had an in‐field recurrence with an ISUP grade of ≥2. Radical treatment in the follow‐up was associated with patients treated by surgeons in group #3 and with elevated post‐HIFU PSA concentrations. Baseline PSA concentrations, group #3 surgeons, and post‐HIFU PSA concentrations were associated with treatment failure. In‐field positive biopsies were associated with baseline and post‐HIFU PSA concentrations. Furthermore, patients treated by surgeons in group #3 were independently associated with radical treatment and focal therapy failure.ConclusionFocal therapy with HIFU has acceptable oncological outcomes in the medium term, and the surgeon's experience and technique are independently associated with the need for subsequent radical treatment and focal therapy failure.