bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parents care needs with epileptic children: a hybrid model concept analysis
Authors: Khalili Arash , Cheraghi Fatemeh , Fayyazi Afshin , Soltanian Alireza , Shamsaei Farshid 
Published: September 2024

Abstract

Background The care needs of epileptic children are a multidimensional concept that varies based on the experience and understanding of family caregivers. This study aimed to concept analysis the care needs of epileptic children's parents.Methods This study was conducted using the hybrid method in three phases. The available literature was systematically searched in the theoretical phase. In the fieldwork phase with a qualitative approach, 13 parents caring for epileptic children were investigated with individual and semi-structured interviews at the Besat Teaching-Treatment Center (Hamadan, Iran) in 2024. In the final phase, the concept of parental care needs was defined based on the findings of the theoretical and fieldwork phases.Results The common antecedents of the theoretical and fieldwork phases included low education levels and poor economic status, and the antecedent of ineffective supporters appeared in the fieldwork phase. The common consequences were care quality improvement, financial burden reduction, care knowledge acquisition, and psychosocial status improvement, and the consequence of increasing stability in the family structure appeared in the fieldwork phase. The care needs of epileptic children's parents included the need for comprehensive support, financial challenges, low care knowledge, therapeutic needs, and psychological challenges. These needs are affected by factors such as poor economic status and low education, and their fulfillment leads to improved quality of life and more effective disease management.Conclusion Concentration on parental care needs and provision of appropriate support through education, financial resources, and social support can help reduce psychosocial pressures on families.
Comparing the effectiveness of CBM treatment and TACS treatment on anxiety, depression, attentional bias, and craving in individuals with opioid use disorder attending addiction treatment camps
Authors: Papia Kiyanoosh , Nosratabadi Masoud , Taremian Farhad , varkiyani Maryam Ebrahimi , Ghanbari Nikzad , docheshmeh Amir Mohamad 
Published: September 2024

Abstract

Introduction:
Substance abuse, especially of opium, represents a major challenge in modern societies, not only impacting individuals' physical and mental health but also giving rise to social problems.
Objective
This research aimed to compare the effectiveness of two treatment methods, CBM (Cognitive Bias Modification) and TACS (Transcranial Alternating Current Stimulation), on reducing anxiety, depression, attentional bias, and craving in individuals with opioid use disorder.
Methods
This study was an experimental research with a pre-test and post-test design. The participants of this study were 72 individuals attending addiction treatment camps who were systematically selected and divided into four treatment groups: CBM treatment, TACS treatment, a combination of both methods, and a control group. Data on demographics were collected using a demographic baseline form of substance abusers, to measure verbal craving induction and visual linear craving scale, and for current craving assessment, a substance craving questionnaire was used, while anxiety and depression levels of participants were measured using the anxiety and depression scale.
Results
The results of the study showed that both treatment methods significantly reduced anxiety and depression. Moreover, the combined CBM and TACS treatment had a greater impact on modifying attentional bias and reducing substance craving compared to each treatment method alone. Furthermore, the comparison between CBM and TACS methods did not show a significant difference in current or induced craving scales (p > 0.05). However, a significant difference was observed in cognitive bias modification (p = 0.012), depression (p = 0.002), and anxiety (p = 0.03) between the simultaneous transcranial electric stimulation and cognitive bias modification.
Discussion
These findings suggest that using a combination of treatment methods can have more efficacy in improving mental health status and reducing substance craving in individuals with opioid dependence.
Day care geriatric mental health services through social prescription by primary health care staff: A Randomized Control Trial at community centers, Chittoor district, A.P., India.
Authors: Tarugu Jayanthi , Koni Kiranmayi , Chaudhuri Sirshendu , KR John , M Krishna A 
Published: September 2024

Abstract

Background:
Health issues among the elderly are inevitable. Mental health problems are common among them and, it is one of the most neglected areas of health. There is a felt need to develop strategies to meet the needs of elderly. Social prescribing is an effective strategy to improve the health and wellbeing of elderly. Hence, this study is planned to estimate the effectiveness of day care geriatric mental health services through social prescription on quality of life (QOL) of elderly aged 60 years and above in rural communities of Chittoor district, Andhra Pradesh.
Methods:
It is a randomized controlled interventional trial, where elderly aged 60 years and above with no acute psychotic symptoms will be recruited from community areas of Chittoor district, Andhra Pradesh. Eligible elderly will be directed to day care geriatric mental health services, where interventions will be planned based on the need assessment. Follow up will be done once in two months to identify the challenges in continuing day care geriatric mental health services. Cost details will be collected concurrently. Analysis will be done applying both intention to treat (ITT) and per protocol analysis. To examine the association between the participant’s characteristics and their QOL, uni-variate analysis will be performed. Thematic analysis will be done to analyse qualitative data where themes and sub-themes will be identified.
Discussion
Mental health services in geriatric population are a neglected area. Day care geriatric mental health services are essential to improve the Quality of living and also their physical and mental health.
Trial registration:
CTRI/2023/03/050503 dated 09/03/2023 under clinical trials registry- India version:1.0 dated 09/03/2023.
Tumour immune cell infiltration and response to FOLFOX or FOLFIRI chemotherapy in colorectal cancer
Authors: Feng Jia , Zhang Lei , Zou You , Liu Rong 
Published: September 2024

Abstract

Background: The immune cell infiltration of tumors has been demonstrated to have a significant part in the response to different cancer treatments. We sought to gain greater understanding of the connections between the immune landscape of colorectal cancer (CRC) tumors and the clinical outcomes of infusional 5-fluorouracil/leucovorin with either oxaliplatin (FOLFOX) or irinotecan (FOLFIRI)-based chemotherapy.
Methods: The immune cell infiltration of CRC tumors was evaluated using data from the TCGA and GEO databases with the CIBERSORTx algorithm. The relative proportion of 22 immune cell subtypes was measured, and their associations with response, progression-free survival (PFS), and overall survival (OS) were investigated. Consensus clustering analysis was utilized for the identification of the immune cell patterns.
Results: We analyzed data from 387 CRC patients and found that drug response rates were negatively correlated with M1 macrophages in the context of FOLFOX chemotherapy. Poor PFS was linked to resting dendritic cells and eosinophils in this regimen. An inverse relationship between drug response rate and M0 macrophages was observed within the FOLFIRI chemotherapy regimen. Activated natural killer cells were connected to poor PFS and OS. Using consensus clustering analysis, we identified three immunological clusters, with a cluster associated with better medication response rates and improved patient outcomes following FOLFOX treatment. This cluster was characterized by higher proportions of M0 macrophages, quiescent memory CD4+ T cells, and quiescent B cells.
Conclusion: Our findings emphasize the significant impact of the CRC tumor-immune milieu on the response to FOLFOX or FOLFIRI chemotherapy. Further investigation of its regulatory mechanisms may contribute to advancements in therapeutic interventions.
Modeling the operating conditions of traction power supply systems incorporating renewable energy sources
Authors: Beloev Ivan , Davtyan Vahe , Kryukov Andrey , Grozev Dimitar , Suslov Konstantin , Kryukov Alexander , Shi Jie , Valeeva Yulia 
Published: September 2024

Abstract

The paper presents the results of research aimed at developing digital models for determining the operating parameters of railway power supply systems equipped with distributed generation plants based on renewable energy sources (RES). RES can be used in railway transport to increase the reliability of power supply to facilities located in areas with insufficiently developed power grid. First of all, this applies to consumers of the first category, whose power failure can lead to significant damage, accidents, and a threat to human life. RES can serve as a basis for independent power sources for consumers of a special group and provide an increase in the efficiency of energy conversion. Furthermore, large-scale implementation of renewable energy sources can significantly reduce energy supply costs and improve the quality of electricity. The study employs a technique of modeling in phase coordinates, which is characterized by the following features: systems approach, which implies determining operating conditions considering the properties and characteristics of complex traction and supply networks; versatility, which provides modeling of power supply systems of various structures and designs; comprehensiveness, which involves calculating normal, emergency, and special operating parameters, which is crucial for the scenarios such as ice melting on catenary wires. The modeling results achieved using the Fazonord software show that the RES-based distributed generation plants provide a variety of beneficial effects: reduction in electricity consumption from power system networks; decrease in the unbalance and harmonic distortion on the busbars of regional windings of traction substations, and stabilization of voltage levels on current collectors of electric locomotives.
CT can enhance the measurement accuracy of radiographic anteversion of acetabular cup following total hip arthroplasty
Authors: Wang Wenzhe , Zhang Zian , Huang Zhenchao , Liu Chang , Wang Qianqian , Zhang Haining 
Published: September 2024

Abstract

Background
This study employed a novel method to measure radiographic anteversion (RA) of acetabular cups following total hip arthroplasty (THA) and validated its accuracy in comparison to traditional methods. The new method involves measuring anatomical anteversion (AA) using CT scans and radiographic inclination (RI) from anteroposterior (AP) radiographs, followed by calculating RA through a mathematical function.
Methods
The imaging data of 152 patients (192 hips) post-THA were retrospectively assessed twice for RA by two independent observers, utilizing Lewinnek’s method, Pradhan’s method, and the new method. Obtaining actual values ​​of RA from patient’s 3D imaging data. The intraobserver and interobserver reliability and accuracy of each method were subsequently compared.
Results
When compared to Lewinnek’s and Pradhan's method, the new method demonstrated superior intraobserver and interobserver reliability. Furthermore, the values obtained through the new method were closer to the actual values for acetabular RA.
Conclusion
Leveraging CT data, the new method introduced in this study enhances the accuracy of acetabular radiographic anteversion measurements.
The Role of Triglyceride-Glucose Index in Central Retinal Artery Occlusion
Authors: Sirakaya Hatice Aslan , Ayyildiz Bekir , Sert Ibrahim Ismet , Kucuk Bekir , Koca Semra , Sirakaya Ender 
Published: September 2024

Abstract

Purpose:To evaluate the correlation between the Triglyceride-Glucose (TyG) index and newly diagnosed cases of central retinal artery occlusion (CRAO) in patients.
Methods: The research involved 51 patients diagnosed with central retinal artery occlusion (CRAO) and a control group consisting of 50 healthy volunteers matched for age and sex. Following a thorough ocular examination, various blood biochemistry and hematological parameters were documented. The TyG index was derived from fasting plasma glucose and triglyceride values.
Results:The average age was 66.1 ± 8.9 years for individuals with CRAO and 64.9 ± 7.6 years for those in the control group. Significant differences in TyG values were observed between the CRAO and control groups, with the CRAO group exhibiting higher values (8.74 ± 0.17 vs. 8.49 ± 0.22, p<0.001). Upon multivariate analysis, the TyG index emerged as an independent predictor of CRAO (Odds Ratio= 1.84, 95% confidence interval = 1.19 – 4.23; p < 0.001). In receiver operating characteristics analysis, the area under the curve for the TyG index was 0.789. A TyG index exceeding 8.58 predicted CRAO with 78% sensitivity and 68% specificity.
Conclusion:The current study demonstrated a notable association between increased TyG index and central retinal artery occlusion (CRAO). Thus, the TyG index could serve as a valuable predictive marker for assessing the risk of CRAO.
Association of both depressive symptoms scores and specific depressive symptoms with cardiovascular disease among middle-aged and older Chinese adults with chronic pain
Authors: Tang Dingzhong , Wang Weiwei , Chen Hong , Song Xiayan , Luo Guojun , Yu Chunli 
Published: September 2024

Abstract

Background There are limited studies on the associations of both depressive symptom scores and specific depressive symptoms with cardiovascular disease (CVD) risk. our purpose was to analyze association of both depressive symptom scores and specific depressive symptoms with CVD among Chinese population with chronic pain. Methods We collected data from the China Health and Retirement Longitudinal Study (CHARLS) during 2011–2015. The primary endpoint of this study was CVD events, which was defined as heart disease or stroke. COX proportional hazards regression was performed to analyze the association of both depressive symptom scores and specific depressive symptoms with CVD events. Results 3401 individuals were included when followed up to 2015, including 304 participants with CVD and 3097 participants without CVD, establishing a CVD incidence of 8.94% after an average follow-up of 46.58 months. The adjusted restricted cubic spline (RCS) curves showed a linear relationship between depression symptom scores and CVD events (P for non-linearity > 0.05). Each 1-point increase in the depression symptom score was associated with a 2% increase in the incidence of CVD events (adjusted HR 1.02, 95% CI: 1.01–1.04). Only 2 specific depressive symptoms were significantly associated with CVD events: feeling hopeless (adjusted HR, 1.11, 95% CI: 1.02–1.22) and feeling lonely (adjusted HR, 1.14, 95% CI: 1.03–1.26). Conclusions This study revealed a significant positive association between elevated depressive symptom scores and high CVD incidence in individual with chronic pain, only two specific depressive symptoms (feeling hopeless and feeling lonely) were independently associated with the development of CVD.
The effect of 5-item modified frailty index on clinical outcomes in elderly rectal cancer patients after curative surgery
Authors: Wu Hong , Shi Feiyu , Hu Chenhao , Zhang Lei , Qu Penghong , She Junjun 
Published: September 2024

Abstract

Frailty is a significant factor contributing to an increased risk of adverse clinical outcomes in older cancer patients. This study aims to investigate the impact of the 5-item modified frailty index (mFI) on both short-term and long-term prognosis in elderly rectal cancer patients who underwent radical resection. And, by integrating the 5-item mFI with clinicopathological characteristics, a postoperative major complications nomogram and a cancer-specific survival (CSS) prediction nomogram were further constructed. Demographic, clinical, and therapeutic data were collected from 1,034 patients aged ≥ 70 years with rectal cancer who underwent proctectomy between 2017 and 2022. Patients were categorized into three groups based on their mFI scores: 318 patients with mFI = 0, 404 patients with mFI = 1, and 312 patients with mFI ≥ 2. Comparisons among these groups revealed that higher 5-item mFI scores were associated with an increased incidence of both overall and major postoperative morbidity, prolonged recovery times, and elevated total medical costs. Multivariate logistic regression analysis indicated that an mFI score of ≥ 2 [odds ratio = 3.145, 95% confidence interval (CI): 2.047–4.833, P < 0.001] was an independent risk factor for major postoperative complications. Similarly, in competing risk analysis, the 5-item mFI was identified as an independent prognostic factor for CSS (subdistribution hazard ratio = 2.00, 95% CI: 1.47–2.72, P < 0.001). The postoperative major complications nomogram and CSS prediction nomogram AUC values were 0.730 and 0.844, respectively, both demonstrating superior predictive capabilities. In conclusion, the 5-item mFI serves as a concise and effective tool for preoperative risk stratification and for predicting clinical outcomes in elderly rectal cancer patients.
Effect of Oblique Laser shock peening on the Wear Resistance of Nitrided H13 Steel Components
Authors: Li Longhui , Li Yi , Liu Judong , Chen Junying , Xu Zhilong , Chen Shiqi , Jiang Qingshan , Chen Xiuyu , Jiang Wenjun , Ma Wenbin 
Published: September 2024

Abstract

This article describes the adoption of an oblique Laser shock peening modification process to perform surface composite modification on nitrided H13 steel. The modified layers are characterized by element distribution, microhardness, surface microstructure, residual stress, and wear morphology. The wear properties of the modified layers were researched through a ball-on-disc (BOD) wear test. The research results showed that oblique Laser shock peening constructs a composite modified layer on the surfaces of nitrided H13 steel components, refining the grain size and significantly improving the hardness and residual stress. However, as the incident angle increases, the magnitude of the increase in hardness and residual stress decreases. The wear test results showed that the wear mechanisms of H13 steel components before and after modification are both abrasive wear and oxidative wear. However, the presence of the composite modified layer helps reduce the depth of surface abrasive wear by 46.3% compared to untreated components. Additionally, the wear properties decrease with an increase in the laser incidence angle.
Barriers in Enabler for Hospitals to Control Hospital- Acquired Infections in India – a Systematic Literature Review
Authors: Htoo San Thaw Tar Nyan , Kamath Rajesh , R Vani Lakshmi , Tiwari Krati 
Published: September 2024

Abstract

Hospital-acquired infections (HAIs) have a substantial impact on patient morbidity, mortality, and healthcare expenditures. They represent a major challenge to global healthcare systems. The prevalence of HAIs is very high in India due to the country's unique issues regarding healthcare infrastructure and infection control methods. With the help of this comprehensive evaluation of the literature, hospitals in India should be able to better manage healthcare-associated infections (HAIs). Included were seven investigations that were carried out in India between 2020 and 2022 and covered a range of geographic areas and healthcare settings. Antibiotic resistance is emphasized in the study as a primary obstacle, underscoring the pressing need for novel therapeutic approaches and infection control measures. Colistin is a possible enabler that shows promise in combating microbes resistant to many drugs. The significance of thorough infection control methods, the difficulties experienced by patient populations, such as newborns and patients with liver illness, and the promise of natural remedies such phytochemicals are some other important findings. The consequences for healthcare policy and practice highlight how critical it is to fortify antibiotic stewardship initiatives and execute evidence-based interventions that are customized for regional settings. Even though this evaluation offers insightful information, more investigation is necessary to fully comprehend the intricate variables affecting HAI control in India and to create more effective preventative and treatment plans.
Enhancing Real-Time Object Detection on Low-End Devices: A Comparative Study of Performance of YOLOv4 and SSD MobileNetv2
Authors: Chimakurthi Ashok Kumar , Chimakurthy Lakshmi Priya 
Published: September 2024

Abstract

This research tackles the challenge of achieving efficient and accurate real-time object detection on low-end devices, such as single-board computers and embedded hardware. Departing from the conventional choice of SSD MobileNetv2, the study opts for the YOLOv4 architecture known for its superior performance in both speed and accuracy. By training the model on a dataset consisting of images captured in densely populated public spaces by surveillance cameras, the focus lies on discerning between individuals and crowds, critical for surveillance and crowd management applications. The hardware setup involves deploying the trained model on a Raspberry Pi 3B, a widely accessible single-board computer, to demonstrate real-world feasibility. Beyond merely showcasing improved stability, precision, and accuracy, the research conducts an in-depth analysis encompassing architectural shifts, relevance of training data, inference speed, and resource utilization, aiming to develop machine learning models specifically tailored for low-resource platforms. This holistic approach seeks to strike a balance between computational affordability and real-time performance, ultimately contributing to advancements in surveillance systems for various practical applications.
Minimally invasive surgery via bilateral thoracotomy for treating left ventricular aneurysm with concomitant ventricular septal rupture
Authors: Li Qianzhen , Chen Xiaodong , Xu Weiye , Chen Liangwan 
Published: September 2024

Abstract

Full median sternotomy is the traditional approach for the treatment of left ventricular aneurysms (LVA) with or without concomitant ventricular septal rupture (VSR). However, it has some disadvantages such as reduced breathing and exercise thoracic stability, which may increase the surgical risk for older or fragile patients. Herein, we report a case of successful minimally invasive bilateral thoracotomy.
Patient and method
A 79-year-old male patient visited our center complaining of breathlessness and orthopnea 21 days after an acute myocardial infarction and percutaneous coronary intervention. An LVA (34.7 mm × 44.4 mm) and a VSR with a diameter of 10 mm close to the apex was detected by echocardiography. Bilateral thoracotomy was performed via two incisions: a 3 cm incision at the right 3rd intercostal space for the aortic root and left atrium vent cannula and aortic clamping; a 7 cm incision at the left 5th intercostal space to expose the apex for LVA and VSR repair. The patient was discharged 7 days postoperatively without any complications.
Conclusion:
LVA with or without VSR can be successfully repaired via bilateral thoracotomy with promising outcomes.