bluuebunny/crossref_metadata_2025_split huggingface dataset:
Froth Flotation of Copper and Copper Compounds from Fine Fractions of Waste Incineration Bottom Ashes
Authors: Breitenstein Boris , Elwert Tobias , Goldmann Daniel , Haas Andrea , Schirmer Thomas , Vogt Volker 
Published: September 2016

AbstractIn Germany about 5 million tons of municipal solid waste incineration (MSWI) bottom ashes are treated for metal recovery annually. With the actual processing metal recovery is realized down to 2 mm. The fractions < 2 mm are utilized without metal recovery. Due to high residual concentrations of non‐ferrous metals in these fractions, especially Cu, several thousand tons of metals are lost every year. This article presents an approach to recover Cu of fine fractions < 0.2 mm by froth flotation. Several collector regimes are screened and flotation parameters are varied. First results exhibit Cu recoveries of 50 % with Cu concentrations of about 5 %.
Patient Satisfaction with Pharmacist‐Led Collaborative Follow‐Up Care in an Ambulatory Rheumatology Clinic
Authors: Hall Jill J. , Katz Steven J. , Cor M. Ken 
Published: September 2016

AbstractObjectivesPatient satisfaction is known to increase with pharmacist intervention in general outpatient clinics and with nurse‐led care in rheumatology clinics. The aim of the present study was to describe and compare patient satisfaction with two different types of care: a pharmacist physician collaborative model and a traditional physician model in a rheumatology clinic setting.MethodsA cross‐sectional survey of inflammatory arthritis patients seen during a follow‐up visit in Edmonton, Alberta, Canada, was conducted over a ten‐week period. Patient satisfaction was measured using a modified version of the validated Leeds Satisfaction Questionnaire, which uses a five‐point Likert scale to measure six dimensions of satisfaction, and compared between the collaborative care and traditional physician models.ResultsA total of 62 patients completed the questionnaire (21 collaborative care and 41 traditional physician model). The average age of respondents was 52 years and the majority were female. The mean score for satisfaction across the six dimensions was 4.56 in the collaborative care group and 4.30 in the traditional physician group (p = 0.02). Patient satisfaction in the collaborative care group was consistently higher across all dimensions. No difference was noted between participants seen for the first time compared with those seen two or more times by the pharmacist.ConclusionsA collaborative care model can exceed the already high expectations for care of patients with inflammatory arthritis. Our findings support the role of pharmacists using a collaborative care approach to care for patients in rheumatology clinics.
Role of the Internet in Care Initiation by People Living With HIV
Authors: Perazzo Joseph , Haas Stephen , Webel Allison , Voss Joachim 
Published: September 2016

AbstractPeople frequently use the internet to obtain information, including information about health, but we lack understanding of how people living with HIV (PLHIV) use the internet in their care and treatment decisions. In this secondary analysis, interviews with 23 individuals who initiated HIV care at an urban, Midwestern medical center and mentioned internet use were analyzed using qualitative content analysis to explore how they used the internet during the process of initiating HIV care. HIV care had been initiated by this sample from less than one month to three years post‐diagnosis. Participants discussed the internet as a source of information about their diagnosis that influenced their care and treatment decisions. Five themes were predominant: (i) The internet alerted me to the possibility of HIV, (ii) the internet showed me a solution is available, (iii) the internet influenced my decisions about care, (iv) the internet empowered me to participate in my treatment decisions, and (v) the internet gave me hope for my future. The results suggest that the internet has the potential to provide information that can profoundly influence PLHIVs’ acceptance of care and treatment decisions. Clinicians face a new reality in which patients use internet resources to obtain information and shape opinions about HIV treatment and care initiation decision‐making. Guiding PLHIV in their selection of online resources is one approach to educating and empowering individuals as they cope with their diagnosis and contemplate decisions regarding HIV care and treatment. © 2016 Wiley Periodicals, Inc.
A Fluorophore‐Free Chemodosimeter for H2S with Luminescence Turn–on Response: Hyrdogen Sulphide Sensing in Garlic Extract
Authors: Maiti Kalipada , Mahapatra Ajit Kumar , Maji Rajkishor , Mondal Sanchita , Ali Syed Samim , Gangopadhyay Ankita , Manna Saikat Kumar , Mandal Sukhendu 
Published: September 2016

AbstractA novel non‐fluorophoric chemodosimeter, 2‐[4‐Diethylamino‐2‐(4‐nitro‐benzyloxy)‐benzylidene]‐malonic acid diethyl ester (1) was developed for the estimation of hydrogen sulphide by exploitation of the ubiquitous reduction of nitro functionality to amino under mild conditions which culminated in the generation of the popular fluorescent moiety, coumarin via tandem nucleophilic addition‐elimination reaction made facile by the structure of the probe molecule. The coumarin moiety produced a brilliant blue fluorescence turn‐on response. Apart from its sensitivity, selectivity and successful application in cellular imaging, a remarkable feature of 1 is its capacity to detect H2S in garlic extract both in presence as well as absence of glutathione which is a crucial player in the pathway for the production of H2S from garlic extract.
Surfactant–free Self‐Templating Construction of BiOCl/BiO1.84H0.08 Nanodisc Heterostructures with Visible‐Light‐Driven Antibacterial Activity
Authors: Wu Dan , Ye Liqun , Wang Wei , Yip Ho Yin , Wong Po Keung 
Published: September 2016

AbstractA unique nanodisc heterostructure is achieved at room temperature without any additional organic surfactants. By using bismuth oxychloride (BiOCl) precursor itself as templates, bismuth oxide hydrates BiO1.8•0.04H2O (BiO1.84H0.08) ultrathin nanosheets are generated to be stacked around the original BiOCl nanodiscs, while the major composition of the inner part remains the precursor itself. Notably, the obtained nanodisc heterostructures well duplicate the size and overall discal shape of the precursor. The structural and crystalline matching of two phases is favour for the morphological construction, further facilitating the separation and transfer of photogenerated charge carries. Significantly, the BiOCl/BiO1.84H0.08 heterostructures exhibit excellent photocatalytic activity in bacterial inactivation under visible light irradiation, which is mainly due to the directly oxidation of photoexcited hole (h+). Accordingly, a h+ transfer process between two phases is proposed. This work will inspire the exploration of a facile way to construct unique heterostructures with diverse photocatalytic applications.
Minding the Genes: a Multidisciplinary Approach towards Genetic Assessment of Cardiovascular Disease
Authors: Rhodes Ashley , Rosman Lindsey , Cahill John , Ingles Jodie , Murray Brittney , Tichnell Crystal , James Cynthia A. , Sears Samuel F. 
Published: September 2016

AbstractGenetic assessment for inherited cardiovascular disease (CVD) is increasingly available, due in part to rapid innovations in genetic sequencing technologies. While genetic testing is aimed at reducing uncertainty, it also produces awareness of potential medical conditions and can leave patients feeling uncertain about their risk, especially if there are ambiguous results. This uncertainty can produce psychological distress for patients and their families undergoing the assessment process. Additionally, patients may experience psychological distress related to living with inherited CVD. In order to more effectively manage the psychosocial challenges related to genetic assessment for CVD, a multidisciplinary model expanded to include psychologists and other allied health professionals is outlined. A case study is provided to illustrate how psychological distress can manifest in a patient living with inherited CVD, as well as proposed psychological management of this patient. Finally, a guide for genetic counselors is provided to aid in identifying and managing common psychological reactions to genetic assessment for CVD.
Lower cerebral blood flow is associated with impairment in multiple cognitive domains in Alzheimer's disease
Authors: Leeuwis Anna E. , Benedictus Marije R. , Kuijer Joost P.A. , Binnewijzend Maja A.A. , Hooghiemstra Astrid M. , Verfaillie Sander C.J. , Koene Teddy , Scheltens Philip , Barkhof Frederik , Prins Niels D. , van der Flier Wiesje M. 
Published: September 2016

AbstractIntroductionWe examined the association between decreased cerebral blood flow (CBF) and cognitive impairment in Alzheimer's disease (AD), mild cognitive impairment (MCI), and subjective cognitive decline (SCD).MethodsWe included 161 AD, 95 MCI, and 143 SCD patients from the Amsterdam Dementia Cohort. We used 3‐T pseudo‐continuous arterial spin labeling to estimate whole‐brain and regional partial volume–corrected CBF. Neuropsychological tests covered global cognition and five cognitive domains. Associations were investigated using linear regression analyses.ResultsIn the whole sample, reduced overall and regional CBF was associated with impairment in all cognitive domains. We found significant interactions between diagnosis and CBF for language and between diagnosis and parietal CBF for global cognition and executive functioning. Stratification showed that decreased CBF was associated with worse performance in AD patients but not in MCI or SCD.DiscussionOur results suggest that CBF may have potential as a functional marker of disease severity.
The Changing Religious Cleavage in Canadians' Voting Behaviour
Authors: Wilkins-Laflamme Sarah 
Published: September 2016

AbstractPast studies have shown that religion plays an important role in voting behaviour in Canada. Yet, little is known about the changes this religious vote has undergone over the past few decades. Using Canadian Election Studies data, we analyze the evolving impact of religious affiliation and level of religiosity on vote choice in federal elections between 1965 and 2011. We find that, as the marginal impact of Catholic and mainline Protestant traditions has declined, the effect of level of religiosity has gained in importance. In 2011, religious citizens were overall more likely to vote Conservative and secular individuals were more likely to vote NDP both in Quebec and in the rest of Canada. Some distinct voting patterns also remain for non-mainline Protestant groups in the ROC and religious nones in Quebec.
IN THE NAME OF A LAW: ISLAMIC LEGAL MODERNISM AND THE MAKING OF AFGHANISTAN'S 1923 CONSTITUTION
Authors: Ahmed Faiz 
Published: September 2016

AbstractIn 1919, a new amir in Afghanistan named Aman Allah Khan launched an ambitious campaign to reorder his government into a constitutional monarchy. By 1923, Afghanistan had ratified its first constitution, supplemented by scores of legal and administrative codes. Whereas the latter have long been attributed to European borrowings or Kemalist imitation, this article uncovers two neglected features of Aman Allah's reformist project to argue that the making of Afghanistan's 1923 Constitution presents a distinctive path of state building in the region: Islamic legal modernism. First, by upholding the Hanafi school of Islamic jurisprudence as the basis of Afghan substantive law, Amir Aman Allah sought a cohesive national judiciary through the codification offiqh, not European civil law. Second, by synthesizing the expertise of a diverse cast of Muslim scholars and professionals—from Afghan clerics to Ottoman and Indian technocrats recruited to Kabul—he attempted to avert a rift between “Islamic” and “secular” lawmaking.
Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance
Authors: Champagne Frances A. 
Published: September 2016

AbstractThe quality of the environment experienced by an individual across his or her lifespan can result in a unique developmental trajectory with consequences for adult phenotype and reproductive success. However, it is also evident that these experiences can impact the development of offspring with continued effect on subsequent generations. Epigenetic mechanisms have been proposed as a mediator of both these within- and across-generation effects, and there is increasing evidence to support the role of environmentally induced changes in DNA methylation, posttranslational histone modifications, and noncoding RNAs in predicting these outcomes. Advances in our understanding of these molecular modifications contribute to increasingly nuanced perspectives on plasticity and transmission of phenotypes across generations. A challenge that emerges from this research is in how we integrate these “new” perspectives with traditional views of development, reproduction, and inheritance. This paper will highlight evidence suggestive of an epigenetic impact of the environment on mothers, fathers, and their offspring, and illustrate the importance of considering the dynamic nature of reproduction and development and inclusive views of inheritance within the evolving field of behavioral and environmental epigenetics.
Lamotrigine compared to placebo and other agents with antidepressant activity in patients with unipolar and bipolar depression: a comprehensive meta-analysis of efficacy and safety outcomes in short-term trials
Authors: Solmi Marco , Veronese Nicola , Zaninotto Leonardo , van der Loos Marc L. M. , Gao Keming , Schaffer Ayal , Reis Catherine , Normann Claus , Anghelescu Ion-George , Correll Christoph U. 
Published: September 2016

ObjectivesTo meta-analytically summarize lamotrigine’s effectiveness and safety in unipolar and bipolar depression.MethodsWe conducted systematic PubMed and SCOPUS reviews (last search =10/01/2015) of randomized controlled trials comparing lamotrigine to placebo or other agents with antidepressant activity in unipolar or bipolar depression. We performed a random-effects meta-analysis of depression ratings, response, remission, and adverse effects calculating standardized mean difference (SMD) and risk ratio (RR) ±95% confidence intervals (CIs).ResultsEighteen studies (n=2152, duration=9.83 weeks) in patients with unipolar depression (studies=4, n=187; monotherapy vs lithium=1, augmentation of antidepressants vs placebo=3) or bipolar depression (studies=14, n=1965; monotherapy vs placebo=5, monotherapy vs lithium or olanzapine+fluoxetine=2, augmentation of antidepressants vs placebo=1, augmentation of mood stabilizers vs placebo=3, augmentation of mood stabilizers vs trancylpromine, citalopram, or inositol=3) were meta-analyzed. Lamotrigine’s efficacy for depressive symptoms did not differ significantly in monotherapy vs augmentation studies (vs. placebo: p=0.98, I2=0%; vs active agents: p=0.48, I2=0%) or in unipolar vs bipolar patients (vs placebo: p=0.60, I2=0%), allowing pooling of each placebo-controlled and active-controlled trials. Lamotrigine outperformed placebo regarding depressive symptoms (studies=11, n=713 vs n=696; SMD=–0.15, 95% CI=–0.27, –0.02, p=0.02, heterogeneity: p=0.24) and response (after removing one extreme outlier; RR=1.42, 95% CI=1.13–1.78; p=0.003, heterogeneity: p=0.08). Conversely, lamotrigine did not differ regarding efficacy on depressive symptoms, response, or remission from lithium, olanzapine+fluoxetine, citalopram, or inositol (studies=6, n=306 vs n=318, p-values=0.85–0.92). Adverse effects and all-cause/specific-cause discontinuation were similar across all comparisons.ConclusionsLamotrigine was superior to placebo in improving unipolar and bipolar depressive symptoms, without causing more frequent adverse effects/discontinuations. Lamotrigine did not differ from lithium, olanzapine+fluoxetine, citalopram, or inositol.
Thinking with Africa
Authors: McGowan Andrew 
Published: September 2016

AbstractAfrica is not only a geographical region but an idea which Westerners, including modern Anglicans, have used ‘to think with’. This includes how accounts of recent Christian growth and decline used by Westerners and Africans alike, and which may require nuance in themselves, have been used questionably in debates about other issues. The real diversity of African Anglican thought and experience offers more complex and enriching possibilities, and should be engaged more directly and fully.
Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue
Authors: Martello Rita , Leutert Mario , Jungmichel Stephanie , Bilan Vera , Larsen Sara C. , Young Clifford , Hottiger Michael O. , Nielsen Michael L. 
Published: September 2016

AbstractAlthough protein ADP-ribosylation is involved in diverse biological processes, it has remained a challenge to identify ADP-ribose acceptor sites. Here, we present an experimental workflow for sensitive and unbiased analysis of endogenous ADP-ribosylation sites, capable of detecting more than 900 modification sites in mammalian cells and mouse liver. In cells, we demonstrate that Lys residues, besides Glu, Asp and Arg residues, are the dominant in vivo targets of ADP-ribosylation during oxidative stress. In normal liver tissue, we find Arg residues to be the predominant modification site. The cellular distribution and biological processes that involve ADP-ribosylated proteins are different in cultured cells and liver tissue, in the latter of which the majority of sites were found to be in cytosolic and mitochondrial protein networks primarily associated with metabolism. Collectively, we describe a robust methodology for the assessment of the role of ADP-ribosylation and ADP-ribosyltransferases in physiological and pathological states.
Feralisation targets different genomic loci to domestication in the chicken
Authors: Johnsson M. , Gering E. , Willis P. , Lopez S. , Van Dorp L. , Hellenthal G. , Henriksen R. , Friberg U. , Wright D. 
Published: September 2016

AbstractFeralisation occurs when a domestic population recolonizes the wild, escaping its previous restricted environment, and has been considered as the reverse of domestication. We have previously shown that Kauai Island’s feral chickens are a highly variable and admixed population. Here we map selective sweeps in feral Kauai chickens using whole-genome sequencing. The detected sweeps were mostly unique to feralisation and distinct to those selected for during domestication. To ascribe potential phenotypic functions to these genes we utilize a laboratory-controlled equivalent to the Kauai population—an advanced intercross between Red Junglefowl and domestic layer birds that has been used previously for both QTL and expression QTL studies. Certain sweep genes exhibit significant correlations with comb mass, maternal brooding behaviour and fecundity. Our analyses indicate that adaptations to feral and domestic environments involve different genomic regions and feral chickens show some evidence of adaptation at genes associated with sexual selection and reproduction.
Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy
Authors: Shao Jundong , Xie Hanhan , Huang Hao , Li Zhibin , Sun Zhengbo , Xu Yanhua , Xiao Quanlan , Yu Xue-Feng , Zhao Yuetao , Zhang Han , Wang Huaiyu , Chu Paul K. 
Published: September 2016

AbstractPhotothermal therapy (PTT) offers many advantages such as high efficiency and minimal invasiveness, but clinical adoption of PTT nanoagents have been stifled by unresolved concerns such as the biodegradability as well as long-term toxicity. Herein, poly (lactic-co-glycolic acid) (PLGA) loaded with black phosphorus quantum dots (BPQDs) is processed by an emulsion method to produce biodegradable BPQDs/PLGA nanospheres. The hydrophobic PLGA not only isolates the interior BPQDs from oxygen and water to enhance the photothermal stability, but also control the degradation rate of the BPQDs. The in vitro and in vivo experiments demonstrate that the BPQDs/PLGA nanospheres have inappreciable toxicity and good biocompatibility, and possess excellent PTT efficiency and tumour targeting ability as evidenced by highly efficient tumour ablation under near infrared (NIR) laser illumination. These BP-based nanospheres combine biodegradability and biocompatibility with high PTT efficiency, thus promising high clinical potential.
Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
Authors: Wang Tong , Martin Sally , Nguyen Tam H. , Harper Callista B. , Gormal Rachel S. , Martínez-Mármol Ramon , Karunanithi Shanker , Coulson Elizabeth J. , Glass Nick R. , Cooper-White Justin J. , van Swinderen Bruno , Meunier Frédéric A. 
Published: September 2016

AbstractAxonal retrograde transport of signalling endosomes from the nerve terminal to the soma underpins survival. As each signalling endosome carries a quantal amount of activated receptors, we hypothesized that it is the frequency of endosomes reaching the soma that determines the scale of the trophic signal. Here we show that upregulating synaptic activity markedly increased the flux of plasma membrane-derived retrograde endosomes (labelled using cholera toxin subunit-B: CTB) in hippocampal neurons cultured in microfluidic devices, and live Drosophila larval motor neurons. Electron and super-resolution microscopy analyses revealed that the fast-moving sub-diffraction-limited CTB carriers contained the TrkB neurotrophin receptor, transiently activated by synaptic activity in a BDNF-independent manner. Pharmacological and genetic inhibition of TrkB activation selectively prevented the coupling between synaptic activity and the retrograde flux of signalling endosomes. TrkB activity therefore controls the encoding of synaptic activity experienced by nerve terminals, digitalized as the flux of retrogradely transported signalling endosomes.
Acoustic omni meta-atom for decoupled access to all octants of a wave parameter space
Authors: Koo Sukmo , Cho Choonlae , Jeong Jun-ho , Park Namkyoo 
Published: September 2016

AbstractThe common behaviour of a wave is determined by wave parameters of its medium, which are generally associated with the characteristic oscillations of its corresponding elementary particles. In the context of metamaterials, the decoupled excitation of these fundamental oscillations would provide an ideal platform for top–down and reconfigurable access to the entire constitutive parameter space; however, this has remained as a conceivable problem that must be accomplished, after being pointed out by Pendry. Here by focusing on acoustic metamaterials, we achieve the decoupling of density ρ, modulus B−1 and bianisotropy ξ, by separating the paths of particle momentum to conform to the characteristic oscillations of each macroscopic wave parameter. Independent access to all octants of wave parameter space (ρ, B−1, ξ)=(+/−,+/−,+/−) is thus realized using a single platform that we call an omni meta-atom; as a building block that achieves top–down access to the target properties of metamaterials.