bluuebunny/crossref_metadata_2025_split huggingface dataset:
Education with interactif website media on patient compliance levels for implementation of post-odontectomy instructions
Authors: Khoirunnisa Nani Mira , Laela Dewi Sodja , Fatikhah Nurul , Heriyanto Yonan 
Published: September 2024

Introduction: Patient compliance with post odontectomy instructions is one of the factors that determine postoperative success. Lack of patient knowledge can interfere with the healing process and cause complications. Instructions given verbally often make patients less aware of post-operative care. Interactive website media through gadgets can be used as a tool to increase patient knowledge as an effort to prevent complications. The purpose of the study was to determine the effect of providing education with interactive website media on the level of patient compliance with post-odontectomy instructions. Methods: The type of research used is pre-experiment research with Post Test Only With Control Group Design. Sampling using Accidental Sampling technique obtained as many as 30 people. The variables in the study were interactive website media and compliance. Hypothesis testing using mann whitney U. Results: The results showed a difference in the level of compliance after being given education through interactive website media between the intervention group (80%) and the control group (53.35%). Mann Whitney U analysis showed that there was an effect on the provision of education with interactive website media on the level of patient compliance with the implementation of post odontectomy instructions p value = 0.049 (p < 0.05). Conclusion Interactive website media can improve patient compliance with instructions given at post odontectomy. Odontectomy patients become more aware of the importance of carrying out postoperative instructions to prevent complications
Informe de Evaluación de Edificios e Inspección Técnica de Edificios en España 2023
Authors: Cerezo-Ibarrondo Álvaro , Lora-Tamayo-Ballvé Marta , Tejerina-González José Ignacio 
Published: September 2024

El Informe de Evaluación de Edificio (IEE), heredero de la Inspección Técnica de Edificio (ITE), se configura como el instrumento de análisis y verificación del cumplimiento de las condiciones básicas de conservación y de comprobación tanto de las condiciones de accesibilidad universal como del comportamiento energético del edificio con carácter básico desde la Ley 8/2013, de 26 de junio, de rehabilitación, regeneración y renovación urbanas (L3R). Sin embargo, tras la STC 143/2017 son las Comunidades Autónomas (CCAA) las competentes para definir, concretar y articular todas sus determinaciones: su sujeción, exenciones, periodicidad, alcance, efectos, contenidos, formatos y registro. El presente estudio de investigación comparado es una radiografía del IEE/ITE en las diecisiete CCAA y en las dos ciudades autónomas españolas al objeto de identificar su grado de desarrollo, sus puntos comunes, divergencias y singularidades tras 10 años desde la L3R.
Closeby Habitable Exoplanet Survey (CHES). II. An Observation Strategy for the Target Stars
Authors: Tan Dongjie , Ji Jianghui , Bao Chunhui , Huang Xiumin , Chen Guo , Wang Su , Dong Yao , Li Haitao , Zhang Junbo , Fang Liang , Li Dong , Deng Lei , Liu Jiacheng , Zhu Zi 
Published: September 2024

Abstract
The Closeby Habitable Exoplanet Survey (CHES) constitutes a mission intricately designed to systematically survey approximately 100 solar-type stars located within the immediate proximity of the solar system, specifically within a range of 10 pc. The core objective of this mission is the detection and characterization of potentially habitable Earth-like planets or super-Earths within the habitable zone of these stars. The CHES mission obtains high-precision astrometric measurements of planets orbiting the target stars by observing angular distance variations between the target star and reference stars. As a result, we surveyed the relevant parameters of both target and reference stars in detail, conducting a thorough analysis and calculation of the required observation accuracy, the number of observations, and the priority assigned to each target star. Observational emphasis will be concentrated on targets considered of higher priority, ensuring the effectiveness of their observation capabilities. Through this approach, we formulate a 5 yr observation strategy that will cover all the target stars within a 6 month time frame. The strategy not only fulfills the required observing capability but also exhibits high efficiency simultaneously, providing an executable program for future mission. Over the span of the mission’s 5 yr duration, a cumulative observation time of 29,220 hr will be available. Approximately 86% of this, totaling 25,120 hr, is allocated for the observation of target stars. This allocation leaves approximately 4100 hr for extended scientific observation programs. We have also performed simulated observations based on this strategy and verified its observational capability for exoplanets.
Detecting and Classifying Flares in High-resolution Solar Spectra with Supervised Machine Learning
Authors: Hao Nicole , Flagg Laura , Jayawardhana Ray 
Published: September 2024

Abstract
Flares are a well-studied aspect of the Sun’s magnetic activity. Detecting and classifying solar flares can inform the analysis of contamination caused by stellar flares in exoplanet transmission spectra. In this paper, we present a standardized procedure to classify solar flares with the aid of supervised machine learning. Using flare data from the RHESSI mission and solar spectra from the HARPS-N instrument, we trained several supervised machine-learning models, and found that the best-performing algorithm is C-Support Vector Classification (SVC) with nonlinear kernels, specifically radial basis functions (RBF). The best-trained model, SVC with RBF kernels, achieves an average aggregate accuracy score of 0.65, and categorical accuracy scores of over 0.70 for the no-flare and weak-flare classes, respectively. In comparison, a blind classification algorithm would have an accuracy score of 0.33. Testing showed that the model is able to detect and classify solar flares in entirely new data with different characteristics and distributions from those of the training set. Future efforts could focus on enhancing classification accuracy, investigating the efficacy of alternative models, particularly deep learning models, and incorporating more data sets to extend the application of this framework to stars that host exoplanets.
Three-dimensional Simulations of the Magnetorotational Instability in Eccentric Disks
Authors: Chan Chi-Ho , Piran Tsvi , Krolik Julian H. 
Published: September 2024

Abstract
Previously we demonstrated that the magnetorotational instability (MRI) grows vigorously in eccentric disks, much as it does in circular disks, and we investigated the nonlinear development of the eccentric MRI without vertical gravity. Here we explore how vertical gravity influences the magnetohydrodynamic (MHD) turbulence stirred by the eccentric MRI. Similar to eccentric disks without vertical gravity, the ratio of Maxwell stress to pressure, or the Shakura–Sunyaev α parameter, remains ∼10−2, and the local sign flip in the Maxwell stress persists. Vertical gravity also introduces two new effects. Strong vertical compression near pericenter amplifies reconnection and dissipation, weakening the magnetic field. Angular momentum transport by MHD stresses broadens the mass distribution over eccentricity at much faster rates than without vertical gravity; as a result, spatial distributions of mass and eccentricity can be substantially modified in just ∼5 to 10 orbits. MHD stresses in the eccentric debris of tidal disruption events may power emission ≳1 yr after disruption.
Dynamical and Secular Stability of Mutually Inclined Planetary Systems
Authors: Bhaskar Hareesh Gautham , Perets Hagai 
Published: September 2024

Abstract
Multiple analytical, semi-analytical, and empirical stability criteria have been derived in the literature for two-planet systems. But, the dependence of the stability limit on the initial mutual inclination between the inner and outer orbits is not well modeled by previous stability criteria. Here, we derive a semi-analytical stability criteria for two-planet systems, at arbitrary inclinations, in which the inner planet is a test particle. Using perturbation theory we calculate the characteristic fractional change in the semimajor axis of the inner binary β = δ
a
1/a
1 caused by perturbations from the companion. Stability criteria can be derived by setting a threshold on β. Focusing initially on circular orbits, we derive an analytical expression for β for coplanar prograde and retrograde orbits. For noncoplanar configurations, we evaluate a semi-analytical expression. We then generalize to orbits with arbitrary eccentricities and account for the secular effects. Our analytical and semi-analytical results are in excellent agreement with direct N-body simulations. In addition, we show that contours of β ∼ 0.01 can serve as criteria for stability. More specifically, we show that (1) retrograde orbits are generally more stable than prograde ones; (2) systems with intermediate mutual inclination are less stable due to von Ziepel–Lidov–Kozai (vZLK) dynamics; and (3) mean motion resonances (MMRs) can stabilize intermediate inclination secularly unstable regions in phase space, by quenching vZLK secular processes (4) MMRs can destabilize some of the dynamically stable regions. We also point out that these stability criteria can be used to constrain the orbital properties of observed systems and their age.
Precise Bolometric Luminosities and Effective Temperatures of 23 Late-T and Y Dwarfs Obtained with JWST
Authors: Beiler Samuel A. , Cushing Michael C. , Kirkpatrick J. Davy , Schneider Adam C. , Mukherjee Sagnick , Marley Mark S. , Marocco Federico , Smart Richard L. 
Published: September 2024

Abstract
We present infrared spectral energy distributions of 23 late-type T and Y dwarfs obtained with the James Webb Space Telescope. The spectral energy distributions consist of NIRSpec PRISM and MIRI low-resolution spectrometer spectra covering the ∼1–12 μm wavelength range at λ/Δλ ≈ 100 and broadband photometry at 15, 18, and 21 μm. The spectra exhibit absorption features common to these objects including H2O, CH4, CO, CO2, and NH3. Interestingly, while the spectral morphology changes relatively smoothly with spectral type at λ < 3 μm and λ > 8 μm, it shows no clear trend in the 5 μm region where a large fraction of the flux emerges. The broad-wavelength coverage of the data enables us to compute the first accurate measurements of the bolometric fluxes of cool brown dwarfs. Combining these bolometric fluxes with parallaxes from Spitzer and Hubble Space Telescope, we also obtain the first accurate bolometric luminosities of these cool dwarfs. We then used the Sonora Bobcat solar-metallicity evolutionary models to estimate the radii of the dwarfs, which results in effective temperature estimates ranging from ∼1000 to 350 K with a median uncertainty of ± 20 K, which is nearly an order of magnitude improvement over previous work. We also discuss how various portions of the spectra either do or do not exhibit a clear sequence when ordered by their effective temperatures.
Intraoperative Electromyogram Analysis of Postural Musculature With Three-dimensional Screen Display Versus Operating Microscope in Ophthalmic Surgery: A Clinical Methods Study
Authors: Hura Arjan S. , Mizrahi Moshe A. , Eluvathingal Charu D. , Quinlan John G. , Neel Robert W. , Riemann Christopher D. 
Published: September 2024

Background and Objective
To objectively analyze the effect of three-dimensional screen-based surgery (3D SBS) versus traditional operating microscope (TOM) on operating surgeon posterior chain postural musculature during ophthalmic surgery. We hypothesized an increase in median amplitude of electromyography (EMG) signals when using a TOM compared to 3D SBS. The goal was to assess surgical ergonomics that may contribute to cervical and lumbar spine pathology. EMG analysis was conducted at the University of Cincinnati Medical Center Epilepsy Monitoring Unit. Data were collected in the private practice setting at Cincinnati Eye Institute.

Materials and Methods

This was an institutional review board exempt, nonrandomized, prospective, single center,
n
= 1 clinical methods study. EMG surface electrodes were affixed to the bilateral splenius capitis, sternocleidomastoid, upper trapezius, anterior deltoid, and quadratus lumborum musculature. EMG data were collected across four sessions consisting of one day each using 3D SBS or a TOM, and two cross-over days. A survey regarding surgeon comfort was administered before, during, and after each surgery, and at the end of each day.

Results
EMG cross-over data demonstrated an increase in muscle activation in all measured muscles except the anterior deltoids and right quadratus lumborum with use of a TOM. Survey data showed increased fatigue when using a TOM relative to 3D SBS.

Conclusion
EMG demonstrated increased postural muscle activation when utilizing TOM relative to 3D SBS. Similar to previous studies, our survey data suggest inferior ergonomics of TOM relative to 3D SBS.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:628–636.]
Relationship Between Janus Kinase Inhibitor Use and Development of Retinal Vein Occlusion
Authors: Chalasani Meghana , Markle Jonathan C. , Shukla Priya , Hajj-Ali Rula A. , Talcott Katherine E. , Singh Rishi P. 
Published: September 2024

Background and Objective
Janus kinase (Jak) inhibitors may have increased risk of thromboembolism compared to tumor necrosis factor (TNF) inhibitors. This study investigates the association between Jak inhibitor use and retinal vein occlusion.

Patients and Methods
This retrospective, non-randomized cohort study used a federated health research network. Propensity-score matched risk ratios with 95% CI were calculated for central and branch retinal vein occlusion (CRVO, BRVO) in patients with immune-mediated inflammatory diseases (IMIDs) treated with Jak inhibitors versus TNF inhibitors.

Results

Jak and TNF inhibitor cohorts each had 5,249 patients. Risk ratio for CRVO with Jak inhibitors (
n
= 11) versus TNF inhibitors (
n
= 18) was 0.61 [CI (0.29,1.29)]. Risk ratio for BRVO with Jak inhibitors (
n
= 17) compared to TNF inhibitors (
n
= 19) was 0.89 [CI (0.47,1.72)].

Conclusion
This study did not find evidence of increased risk of RVO with the use of Jak inhibitors compared to TNF inhibitors among patients with IMIDs, contributing to literature on Jak inhibitor safety.

[
Ophthalmic Surg Lasers Imaging Retina
2025;56:72–78.]
Comparison of the Effect of Auriculotherapy, a Herbal Compound (Aslagh Capsule), and Metformin on the Clinical Symptoms of Polycystic Ovary Syndrome: Randomized Clinical Trial
Authors: Ghanbarian Razieh , Valiani Mahboubeh , Allameh Zahra , Ranjbar Maryam , Mazaheri Mohammad 
Published: September 2024

Background:
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects women of child-bearing age, with a worldwide prevalence ranging from 6 to 20%. Considering the potential side effects of chemical medications and the need for long-term drug administration, complementary treatments such as acupuncture, auriculotherapy, and herbal medicine have been considered. Hence, this study was designed to compare the effects of auriculotherapy, a herbal component (Aslagh capsule), and metformin on the clinical symptoms of PCOS.

Materials and Methods:
This is a randomized controlled clinical trial study, which allocated 24 women, aged 18–43 years old, with oligomenorrhea in PCOs, in a 1:1:1 ratio, to three groups.

Result:
A decreasing pattern in the duration of the menstrual cycle was observed in all three groups, but this was significant only in the auriculotherapy group. There were no significant differences between the three groups in acne and hirsutism scores. However, there was a significant reduction in excess hair growth and density of hair in the auriculotherapy group compared to the other two groups (P < 0.05). Besides, in the auriculotherapy group, the reduction in thickness of excess hair at the end of the second and third months of treatment were marginally significant compared to the two other groups.

Conclusions:
Auriculotherapy and Aslagh capsule can be effective in reducing PCOS symptoms, similar to metformin. However, auriculotherapy is more effective than the other treatments in reducing the duration of the menstrual cycle, excess hair growth, and hair density.
Evaluation of the Relationship between Early Clinical Manifestations and Changes in Biochemical, Inflammatory, and Coagulation Parameters and the Prognosis of Pregnant Women with COVID-19 Admitted to the ICU
Authors: Ebrahim Babai Mahtab , Kabiri Azita , Movahedi Minoo , Ghahiri Ataollah , Hajhashemi Maryam , Dehghan Maryam 
Published: September 2024

Background:
In the SARSCov2 virus epidemic, pregnant women are more susceptible to infectious diseases due to changes in biochemical parameters and are at higher risk of severe respiratory disease and pneumonia. This study aimed to evaluate the biochemical, inflammatory and coagulation parameters in pregnant women with severe disease conditions (as one of the high-risk groups) as well as prognosis and outcome.

Materials and Methods:
This cross-sectional study was performed on 135 pregnant women with COVID-19 admitted to ICU. Demographic and clinical information and laboratory parameters of the patients were evaluated and recorded at the time of admission and in the next follow-up until discharge or death in addition to the outcome and also the pregnancy outcome.

Results:
The mortality rate of pregnant women with COVID-19 was 9.6%. The mortality rate decreases with increasing Hb (OR (95% CI): 0.68 (0.47-0.99); P value = 0.043) and lymphocytes (OR (95% CI): 0.92 (0.85-0.96); P value = 0.028) and will increase significantly with increasing PT (OR (95% CI): 1.24 (1.01-1.51); P value = 0.037), INR (OR (95% CI): 1.89 (1.26-2.25); P value = 0.004), D-dimer (OR (95% CI): 1.68 (1.10-2.08); P value = 0.027), and LDH (OR (95% CI): 1.20 (1.01-1.61); P value = 0.010).

Conclusion:
According to the results of the present study, inflammatory factors such as leukocytes, neutrophils, NLR, CRP have an increasing and lymphocytes have a decreasing trend, so that lymphocytopenia is more common in non-survivors. In addition, increase of PT, INR, D-dimer and LDH and decrease of Hb were significantly associated with increased chance of mortality. But fibrinogen, ferritin, ALT and AST were not significantly associated with mortality in these women.
The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial
Authors: Sadeghi Masoumeh , Momeni Ali , Mirsaeidi Fatemeh S. , Jamalian Marjan , Amirpour Afshin , Hadavi Mohammad M. , Tavassoli Parsa , Taheri Marzieh , Azizi Elham , Rouhani Sina , Roohafza Hamid 
Published: September 2024

Background:
Atherosclerosis is the main process in coronary artery stenosis, which is exacerbated by vitamin D deficiency. This study aims to investigate the relationship between vitamin D deficiency treatment, lipid profile, and C-reactive protein (CRP) in ischemic heart disease (IHD).

Materials and Methods:
This is a double-blind, randomized clinical trial involving 44 IHD patients with hypovitaminosis, aged 40–65 years, who were referred to Chamran Specialty Heart Hospital, Isfahan, Iran. Participants were randomly divided into two groups: The intervention group received weekly doses of 50,000 units of vitamin D3 for 5 weeks, while the placebo group received a control substance. CRP and serum lipid profiles, including total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), were assessed before and after the intervention. Trial registration number: IRCT20200905048622N1.

Results:
The mean age of the IHD patients was 57.84 ± 9.66 years, and among all 44 patients, 40 patients (91%) were male In the intervention group receiving vitamin D3, serum levels of HDL (P = 0.048) and 25-hydroxyvitamin D (25(OH)D) (P < 0.001) increased, while serum level of TG (P = 0.008) decreased significantly. In the placebo group, HDL level (P = 0.007) was increased and alanine transaminase (ALT) (P = 0.05) was significantly decreased. The results showed that the correlation between serum 25(OH)D treatment and CRP level was not significant.

Conclusion:
Vitamin D supplementation in IHD patients led to notable improvements in lipid profiles, including increased HDL-C levels and decreased TG levels. These findings hold potential clinical implications for healthcare professionals in managing risk factors in IHD patients.
Exploring the clinical implications of novel SRD5A2 variants in 46,XY disorders of sex development
Authors: Mao Yu , Huang Jian-Mei , Chen-Zhang Yu-Wei , Lin He , Zhang Yu-Huan , Jiang Ji-Yang , Wu Xue-Mei , Liao Ling , Tang Yun-Man , Yang Ji-Yun 
Published: September 2024

Abstract
This study was conducted retrospectively on a cohort of 68 patients with steroid 5 α-reductase 2 (SRD5A2) deficiency and 46,XY disorders of sex development (DSD). Whole-exon sequencing revealed 28 variants of SRD5A2, and further analysis identified seven novel mutants. The preponderance of variants was observed in exon 1 and exon 4, specifically within the nicotinamide adenine dinucleotide phosphate (NADPH)-binding region. Among the entire cohort, 53 patients underwent initial surgery at Sichuan Provincial People’s Hospital (Chengdu, China). The external genitalia scores (EGS) of these participants varied from 2.0 to 11.0, with a mean of 6.8 (standard deviation [s.d.]: 2.5). Thirty patients consented to hormone testing. Their average testosterone-to-dihydrotestosterone (T/DHT) ratio was 49.3 (s.d.: 23.4). Genetic testing identified four patients with EGS scores between 6 and 9 as having this syndrome; and their T/DHT ratios were below the diagnostic threshold. Furthermore, assessments conducted using the crystal structure of human SRD5A2 have provided insights into the potential pathogenic mechanisms of these novel variants. These mechanisms include interference with NADPH binding (c.356G>C, c.365A>G, c.492C>G, and c.662T>G) and destabilization of the protein structure (c.727C>T). The c.446-1G>T and c.380delG variants were verified to result in large alterations in the transcripts. Seven novel variations were identified, and the variant database for the SRD5A2 gene was expanded. These findings contribute to the progress of diagnostic and therapeutic approaches for individuals with SRD5A2 deficiency.