bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personality, coping, and social support as predictors of long‐term quality‐of‐life trajectories in older breast cancer survivors: CALGB protocol 369901 (Alliance)
Authors: Durá‐Ferrandis Estrella , Mandelblatt Jeanne S. , Clapp Jonathan , Luta George , Faul LeighAnne , Kimmick Gretchen , Cohen Harvey Jay , Yung Rachel L. , Hurria Arti 
Published: February 2017

AbstractBackgroundTo determine long‐term quality‐of‐life (QOL) trajectories among breast cancer survivors aged 65+ (older) evaluating the effects of personality and social support.MethodsOlder women (N = 1280) newly examined with invasive, nonmetastatic breast cancer completed baseline assessments. Follow‐up data were collected 6 and 12 months later and then annually for up to 7 years (median 4.5 years). Quality of life was assessed using EORTC‐QLQ‐C30 emotional, physical, and cognitive scales. Optimism (Life Orientation Test), Coping (Brief COPE), and social support (Medical Outcomes Study) were assessed at baseline. Group‐based trajectory modeling identified QOL trajectories; multinomial regression evaluated effects of predictors on trajectory groups. Age, education, systemic therapy, comorbidity, and reported precancer function (SF‐12) were considered as controlling variables.ResultsThree trajectories were identified for each QOL domain: “maintained high,” “phase shift” (lower but parallel scores to “maintained high” group), and “accelerated decline” (lowest baseline scores and steepest decline). Accelerated decline in emotional, physical, and cognitive function was seen in 6.9%, 31.8%, and 7.6% of older survivors, respectively. Maladaptive coping and lower social support increased adjusted odds of being in the accelerated decline group for all QOL domains; lower optimism was only related to decline in emotional function. Chemotherapy was related to physical and cognitive but not emotional function trajectories.ConclusionsPersonality and social resources affect the course of long‐term emotional well‐being of older breast cancer survivors; treatment is more important for physical and cognitive than emotional function. Early identification of those vulnerable to deterioration could facilitate clinical and psychological support.
Feasibility of multiple breath washout measurements in infants with bronchiolitis: A pilot study
Authors: Stafler Patrick , Weinreb Sigal , Mussaffi Huda , Mei‐Zahav Meir , Prais Dario , Steuer Guy , Bar‐On Ophir , Hoshen Moshe , Blau Hannah 
Published: February 2017

AbstractBACKGROUNDLung clearance index (LCI) reflects ventilation inhomogeneity and is raised in obstructive airway disease. Feasibility of multiple breath washout (MBW) measurement during acute lung disease in infants is unknown. As a further measure of disease, exhaled nitric oxide (eNO) may paradoxically decrease in acute bronchiolitis. We hypothesized that MBW measurements were attainable in infants with bronchiolitis and that LCI was raised and eNO reduced, compared to normal controls.METHODSInfants with acute bronchiolitis were tested with sulfur hexafluoride (SF6) MBW during hospitalization and compared to controls. Tidal breathing and eNO parameters were obtained. Measurements were performed during natural sleep.RESULTSTwenty‐nine infants with bronchiolitis aged 3.7 ± 2.3 months (mean ± SD) and 23 controls aged 4.2 ± 2.5 months (P = 0.07) were evaluated. Fifteen of 29 (52%) infants with bronchiolitis and 19/23 (83%) controls achieved ≥2 valid MBW measurements. Reasons for test failure included waking up during facemask application and an irregular respiratory pattern. LCI was 8.4 ± 0.8 in the study group and 7.3 ± 0.7 in controls (P < 0.001). ENO was 2.3 ± 2.7 ppb in the study group and 7.9 ± 6.9 ppb in controls (P = 0.004).CONCLUSIONMBW measurements during natural sleep are feasible but technically challenging in infants with acute bronchiolitis. LCI is raised compared to healthy controls. Larger trials, possibly using sedation protocols and shortened washout periods, are required to corroborate these findings. LCI can potentially serve as an objective indicator of severity and could be considered as a biomarker for future interventional trials.
Synthesis and in vivo fungicidal activity of some new quinoline derivatives against rice blast
Authors: Liu Xing‐Hai , Fang Yue‐Ming , Xie Feng , Zhang Rui‐Rui , Shen Zhong‐Hua , Tan Chen‐Xia , Weng Jian‐Quan , Xu Tian‐Ming , Huang Hong‐Ying 
Published: February 2017

AbstractBACKGROUNDQuinoline derivatives possess excellent fungicidal activity against rice blast, but quinoline derivatives have not been thoroughly explored as fungicides. In the process of designing new fungicides, the 1,1,1,2,3,3,3‐heptafluoropropan‐2‐yl group was introduced in order to find new structure quinoline derivatives.RESULTSSeventeen new quinoline derivatives containing 1,1,1,2,3,3,3‐heptafluoropropan‐2‐yl moiety were designed and synthesised. In vivo fungicidal activities of these compounds were tested against rice blast. Some of the compounds provided effective control at 100 mg L−1, and a few compounds were effective at 10 mg L−1. Furthermore, a density functional theory study established the structure–activity relationships of the synthesised compounds.CONCLUSIONQuinoline derivatives, especially benzyl (2,3,8‐trimethyl‐6‐(perfluoropropan‐2‐yl)quinolin‐4‐yl) carbonate, which possess good control effective against rice blast and cucumber powdery mildew, may become new lead compounds for the development of fungicides with further structure modification. © 2017 Society of Chemical Industry
Pauli spin blockade in CMOS double quantum dot devices
Authors: Kotekar‐Patil D. , Corna A. , Maurand R. , Crippa A. , Orlov A. , Barraud S. , Hutin L. , Vinet M. , Jehl X. , De Franceschi S. , Sanquer M. 
Published: February 2017

AbstractSilicon quantum dots are attractive candidates for the development of scalable, spin‐based qubits. Pauli spin blockade in double quantum dots provides an efficient, temperature independent mechanism for qubit readout. Here, we report on transport experiments in double gate nanowire transistors issued from a complementary metal–oxide–semiconductor (CMOS) process on 300 mm silicon‐on‐insulator wafers. At low temperature the devices behave as two few‐electron quantum dots in series. We observe signatures of Pauli spin blockade with a singlet–triplet splitting ranging from 0.3 to 1.3 meV. Magneto‐transport measurements show that transitions which conserve spin are shown to be magnetic‐field independent up to T.
Flocking of multi‐agent nonholonomic systems with unknown leader dynamics and relative measurements
Authors: Zhao Xiao‐Wen , Guan Zhi‐Hong , Li Juan , Zhang Xian‐He , Chen Chao‐Yang 
Published: February 2017

SummaryIn this paper, we consider the distributed flocking control problem of multi‐agent nonholonomic systems with a virtual leader whose dynamics is unknown; state information is time varying and not available to all agents under both fixed and switching topologies. On the basis of the relative velocity and orientation information of neighboring agents, two distributed discontinuous control protocols are designed for fixed and switching topologies, respectively. By using tools from algebraic graph theory and nonsmooth analysis, the proposed distributed discontinuous control protocols guarantee that the velocities and orientations of the agents exponentially converge to the velocity and orientation of the virtual leader, respectively, while ensuring collision avoidance of the whole group, if the interaction graph among agents is undirected and the virtual leader with bounded time‐varying velocity has directed paths to other agents. Finally, numerical simulations are provided to illustrate the effectiveness of the theoretical results. Copyright © 2017 John Wiley & Sons, Ltd.
Sustainable Development: The Effects of Social Normative Beliefs On Environmental Behaviour
Authors: Wang Edward Shih‐Tse , Lin Hung‐Chou 
Published: February 2017

AbstractSustainable development has become a global concern because of problems of environmental pollution, energy consumption and climate change. Sustainable development requires that individuals from all sectors contribute to protecting the environment. Although numerous studies have investigated the relationship between social normative beliefs and environmental behaviour, the results of these studies have varied. Scant attention has been devoted to clarifying the mechanism underlying the influence of social normative beliefs on environmental behaviour by testing mediators. The present study explored the mediating effect of environmental perceptions on the relationship between social normative beliefs and environmental behaviour. A convenience sampling method was employed to establish a sample consisting of 453 young adults aged 18–30 years. Structural equation modelling was employed for data analyses. Results revealed that environmental perceptions (perceived effectiveness and environmental responsibility) completely mediate the relationship between social normative beliefs (descriptive normative beliefs and injunctive normative beliefs) and environmental behaviour. This finding suggests that environmental practitioners might develop effective programs that motivate individuals to engage in environmental behaviour to achieve sustainable development from the social influence perspective. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
What Does the Media Mean by ‘Sustainability’ or ‘Sustainable Development’? an Empirical Analysis of Sustainability Terminology in German Newspapers Over Two Decades
Authors: Fischer Daniel , Haucke Franziska , Sundermann Anna 
Published: February 2017

AbstractThere is broad agreement that the regulative idea of sustainability needs to be specified in public deliberation so that it can contribute to sustainable development policies and practices. The media plays a critical role in this endeavor. However, journalists commonly criticize the terminology of ‘sustainability’ and ‘sustainable development’ as blurred, fuzzy and ambiguous. The vibrant controversy over how journalists should engage with the sustainability terminology is however facing an apparent lack of research on how sustainability terminology actually has been embraced and used in the media.This study aims to close the aforementioned research gaps in providing a twofold account of the field in Germany. First, in a trend analysis, it sketches the usage of sustainability terminology in six major German newspapers from 1995 to 2015. Second, in an in‐depth analysis for the three years 2001, 2007 and 2013, more than 16 000 usages of sustainability terminology have been coded according to their underpinning meaning. The findings show that sustainability terminology in major German newspapers is used in about twice as many articles in 2015 compared with 1995. What changes is not only the frequency, but also the meanings, with which sustainability terminology is used. There is an apparent tendency towards a ‘semantic consolidation’ of sustainability terminology in the post‐2000 years. The meaning thereby moves away from a non‐specific and replaceable fashion word towards a more sophisticated and elaborated reflection of the concept of sustainable development. Data analysis finds that political alignment of the newspaper plays a critical role in this. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced by β‐amyloid oligomers
Authors: Almeida D.S. , Santos R.S. , Anjos M.J. , Ferreira S.T. , Souza A.S. , Lopes R.T. 
Published: February 2017

Alzheimer's disease (AD) is an insidious, progressive, and irreversible brain disorder that leads to memory loss and severe cognitive decline. However, the discovery that soluble β‐amyloid oligomers are potent central nervous system neurotoxins has led to a new view of AD pathogenesis. Metals, such as zinc, iron, and copper, are all increased in the aged brain, and the contents of those metals in the brain of AD patients are higher than non‐AD people. So, altered homeostasis of metal may result in the development of AD. Total reflection X‐ray fluorescence analysis (TXRF) is a multielement analytical technique, which can be used for elemental trace analysis. In this work, TXRF was used to evaluate the elemental concentration and distribution on mice brain regions. Three groups were studied: control, AD10, and AD100, being the two latter were given a single intracerebroventricular injection of 10 pmol and 100 pmol (β‐amyloid oligomers), respectively, to induce experimental AD. All samples were submitted to acid digestion. The TXRF measurements were performed at the X‐Ray Fluorescence Beamline at Brazilian National Synchrotron Light Laboratory, using a monochromatic beam (11.5 keV) for the excitation. It was possible to determine the concentrations of the following elements: P, S, K, Fe, Cu, and Zn. Results showed differences in the elemental concentration in some brain regions between the AD groups and the control group. Furthermore, the difference in the hypothalamus in AD10 groups, both female and male, suggests an association between AD and changes in these elements. Copyright © 2017 John Wiley & Sons, Ltd.
Daytime Locations in Spatial Mismatch: Job Accessibility and Employment at Reentry From Prison
Authors: Sugie Naomi F. , Lens Michael C. 
Published: February 2017

AbstractIndividuals recently released from prison confront many barriers to employment. One potential obstacle is spatial mismatch—the concentration of low-skilled, nonwhite job-seekers within central cities and the prevalence of relevant job opportunities in outlying areas. Prior research has found mixed results about the importance of residential place for reentry outcomes. In this article, we propose that residential location matters for finding work, but this largely static measure does not capture the range of geographic contexts that individuals inhabit throughout the day. We combine novel, real-time GPS information on daytime locations and self-reported employment collected from smartphones with sophisticated measures of job accessibility to test the relative importance of spatial mismatch based on residence and daytime locations. Our findings suggest that the ability of low-skilled, poor, and urban individuals to compensate for their residential deficits by traveling to job-rich areas is an overlooked and salient consideration in spatial mismatch perspectives.
Maternal dipyrone treatment during lactation in mice reduces maternal behavior and increases anxiety‐like behavior in offspring
Authors: Veronesi Vanessa Barbosa , Batista Tatiane Helena , Ribeiro Ana Cláudia Alves Freire , Giusti‐Paiva Alexandre , Vilela Fabiana Cardoso 
Published: February 2017

AbstractDipyrone (metamizole), a powerful drug, is widely used as an analgesic and antipyretic; however, the safety of its use during lactation and the potential impact on the offspring are not well established. This study aimed to determine the effect of maternal dipyrone treatment during lactation on offspring development and emotional behavior and on the dam's maternal behavior. Hence, on postnatal day (PND) 2, drinking water only or drinking water containing dipyrone at doses of 100, 300, and 500 mg/kg/day, were offered to lactating mothers up to PND9. Thereafter, all mice were provided regular drinking water. On PND2, all litters were culled to 8 pups (4 males and 4 females). Maternal behavior was evaluated at PND3, 6, 9, and 12, and at PND7 we evaluated locomotor activity in the open field. Reflex parameters and physical development of offspring were evaluated during lactation. At PND7, analysis of ultrasonic vocalization (USV) was performed. When the animals reached adolescence, we evaluated their performance in the open field, elevated plus maze (EPM), and marble burying. Our data demonstrated that maternal dipyrone treatment during lactation not only altered maternal behavior and the onset of physical and neurodevelopmental landmarks but also had an impact on anxiety‐like behavior in offspring.
Airway support using a pediatric intubation tube in adult patients with atrial fibrillation: A simple and unique method to prevent heart movement during catheter ablation under continuous deep sedation
Authors: Takigawa Masateru , Takahashi Atsushi , Kuwahara Taishi , Okubo Kenji , Nakashima Emiko , Watari Yuji , Yamao Kazuya , Nakajima Jun , Tanaka Yasuaki , Takagi Katsumasa , Kimura Shigeki , Hikita Hiroyuki , Hirao Kenzo , Isobe Mitsuaki 
Published: February 2017

AbstractBackgroundThe present study aimed to elucidate the safety and effectiveness of a noble and unique airway management technique in which a pediatric intubation tube is used in adult patients with atrial fibrillation (AF) undergoing catheter ablation (CA) under continuous deep sedation.MethodsIn total, 246 consecutive patients with AF (mean age, 65±10 years; 60 women) underwent CA under dexmedetomidine‐based continuous deep sedation. A 4‐mm pediatric intubation tube guided by a 10‐French intratracheal suction tube was inserted smoothly, and the tip of the tube was located at the base of the epiglottis. The maximum shifting distance of the heart (MSDH) was measured with the 3D mapping system (Ensite NavX system) before and after inserting the pediatric intubation tube.ResultsAt baseline, the MSDH of patients under continuous deep sedation was 23±14 mm. The pediatric intubation tube reduced the MSDH to 13±6 mm (mean reduction from baseline, 38.4±21.7%; P<0.0001). In contrast, oxygen saturation was significantly increased from 89±8% to 95±3% (P<0.0001). The mean distance between the nostril and base of the epiglottis was 16.6±0.5 mm. Major periprocedural complications occurred in 9 (3.6%) patients including 3 (1.2%) cardiac tamponade and 6 (2.4%) phrenic nerve injury cases. Larger MSDH (odds ratio, 1.13; 95% confidence interval, 1.04–1.25; P=0.007) was a significant predictor of major periprocedural complications. No major airway complications occurred, except in 3 patients (1.2%) who had minor nasal bleeding.ConclusionThis unique airway management technique using a pediatric intubation tube for CA procedures performed in adult patients with AF under continuous deep sedation was easy, safe, and effective.
A Consult Is Just a Page Away: A Prospective Observational Study on the Impact of Jinxing on Call Karma in Neurosurgery
Authors: Joswig Holger , Zarnett Lauren , Steven David A. , Stienen Martin N. 
Published: February 2017

AbstractObjective: Our aim was to assess the impact of jinxing on “call karma” in neurosurgery. Methods: We conducted a prospective observational study on 15 residents on call for the neurosurgery service, recording the total number of admissions, consults, deaths encountered, surgeries performed, hours of sleep and subjective call rating on a numeric rating scale (NRS) of 0-10 in terms of general awfulness. Results: Some 204 on-call nightshifts were analyzed, of which 61 (29.9%) were jinxed and 143 (70.1%) were nonjinxed. Jinxes seemed to occur in clusters. The baseline parameters (experience, type of call coverage and superstition level) of the study groups were well balanced. A trend toward more surgeries was observed during jinxed nights, where residents slept significantly less (mean 147.8±96.2 vs. 180.9±106.1 min, p=0.037) and rated their on-call experience worse on the NRS (4.4±2.2 vs. 3.5±2.0, p=0.011), while there was no significant difference in number of admissions, consults or deaths. Conclusions: The act of jinxing ought to be avoided in the neurosurgical setting, as it might be potentially harmful to resident call karma, irrespective of level of experience, resources and personal beliefs.
Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions
Authors: Reyes Maria M. , Munigala Satish , Church Emily L. , Kulik Tobias B. , Keyrouz Salah G. , Zipfel Gregory J. , Warren David K. 
Published: February 2017

OBJECTIVETo evaluate the agreement between the current National Healthcare Safety Network (NHSN) definition for ventriculitis and others found in the literature among patients with an external ventricular drain (EVD)DESIGNRetrospective cohort study from January 2009 to December 2014SETTINGNeurology and neurosurgery intensive care unit of a large tertiary-care centerPATIENTSPatients with an EVD were included. Patients with an infection prior to EVD placement or a permanent ventricular shunt were excluded.METHODSWe reviewed the charts of patients with positive cerebrospinal fluid (CSF) cultures and/or abnormal CSF results while they had an EVD in place and applied various ventriculitis definitions.RESULTSWe identified 48 patients with a total of 52 cases of ventriculitis (41 CSF culture-positive cases and 11 cases based on abnormal CSF test results) using the NHSN definition. The most common organisms causing ventriculitis were gram-positive commensals (79.2%); however, 45% showed growth of only 1 colony on 1 piece of media. Approximately 60% of the ventriculitis cases by the NHSN definition met the Honda criteria, approximately 56% met the Gozal criteria, and 23% met Citerio’s definition. Cases defined using Honda versus Gozal definitions had a moderate agreement (κ=0.528; P<.05) whereas comparisons of Honda versus Citerio definitions (κ=0.338; P<.05) and Citerio versus Gozal definitions (κ=0.384; P<.05) had only fair agreements.CONCLUSIONSThe agreement between published ventriculostomy-associated infection (VAI) definitions in this cohort was moderate to fair. A VAI surveillance definition that better defines contaminants is needed for more homogenous application of surveillance definitions between institutions and better comparison of rates.Infect Control Hosp Epidemiol 2017;38:574–579
WHEN DO CITIZENS TAKE COSTLY ACTION AGAINST GOVERNMENT CORRUPTION? EVIDENCE FROM EXPERIMENTS IN AUSTRALIA, SINGAPORE, AND THE UNITED STATES
Authors: Yap O. Fiona 
Published: February 2017

AbstractWhen do citizens take costly collective action against government corruption? When citizens act in concert, their demands are credible and not easily discounted by governments, which should be more likely to respond. In this study, we use the stag-hunt game, supplemented by Granovetter's threshold model of collective action, to investigate the conditions under which citizens coordinate to collectively act against government corruption. We use survey experiments in laboratory settings in Australia, Singapore, and the United States. The results show several conditions motivate participants to pursue collective action; using the wellspring of the theoretical argument, they clarify that information that others pursue collective action, together with clear mutual benefits as measured by rewards, are primary motivators of the individual's choice. Correspondingly, other considerations, including initial costs or final potential penalties, do not bear on the individual's choice. The findings have implications not only for the empirical literature on policy but also for policy debates on how to control it.