bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fracture failure of oil-collecting steel wire reinforced thermoplastic composite pipe
Authors: Ding Han , Zhang Aibo , Li Houbu , Qi Dongtao , Qi Guoquan , Lun Huilin 
Published: October 2024

A steel wire-reinforced thermoplastic composite pipe (SRTP) used as an oil connecting experienced fracture failure after 1.8 years’ service. In this paper, we conducted through on-site working condition investigation, visual physical inspection, analysis of the inner lining structure composition, physical and chemical properties analysis, thermal analysis, and mechanical analysis, and morphology analysis. The lining material of the SRTP exhibited significant swelling, which reduced its performance, and operation at high temperatures (>75°C) accelerated this process. Due to the swelling of oil and the permeation of CO2 and H2S, the oil and acid gases penetrated the interlayer of the composite pipe and accumulated in the annular space, continuously corroding and weakening the steel wire. This process gradually reduced its load-bearing capacity and pressure resistance. It is recommended that non-metallic pipes should be selected according to the service conditions to ensure that the materials are consistent with the design requirements.
The effect of role play prepared with video support on ethical decision-making and motivation levels of nursing students: A quasi-experimental study
Authors: Demircan Burcu , Kıyak Yasemin , Aştı Türkinaz 
Published: October 2024

Background: Since the increasingly complex structure of health care services brings many ethical problems, it is important to use different instructional technologies in the ethical education of future nurses. Aim: The aim of this study was to determine the effect of role play prepared with video support on ethical decision-making and motivation levels of nursing students. Research design: A quasi-experimental study with pretest-posttest design. Participants and research context: The research was conducted in the Nursing Department of a University located in Istanbul, Turkey between October 15 and November 15, 2024. The sample of the research consisted of 3rd year nursing students. Data were collected using the Descriptive Characteristics Form, the Nursing Dilemma Test, and the Instructional Material Motivation Scale for Single-Use. Ethical considerations: Permission was obtained from Bezmialem Vakif University Non-Interventional Ethical Research Committee and the institution where the study was conducted for the implementation of the research. Written and verbal consent was obtained from all participants in accordance with the Helsinki Declaration. Findings: While there was no difference between the students’ Ethical Dilemma Test Principled Thinking pre-test and post-test scores, their Practical Consideration ( p = .005) and motivation levels ( p = .037) post-test scores were found to be higher. There was a weak but significant negative correlation between academic achievement and pre-test teaching material motivation levels (r = −0.375, p = .041). Discussion: The use of different teaching methods and techniques in ethics education in nursing is important for future nurses to find more practical solutions to the ethical problems they will encounter during patient care. Conclusion: The results of the study indicate that the use of video-supported role play can be effective in teaching ethics courses in nursing education.
Prognostic Role of Temperature Oxygenation Perfusion Sugar (TOPS) score in Outborn Transported Neonates in a Tertiary Care Center—A Prospective Cohort Study
Authors: Charki Siddu , Khasage Udaykumar , Biradar Vijayakumar S. , Salunkhe Manasi , Patil Mallangouda M. 
Published: October 2024

Background Neonatal outcomes are affected by the acute physiologic derangements of neonatal vitals, such as temperature, blood sugar (GRBS), perfusion, and oxygenation. The aim was to correlate the temperature oxygenation perfusion sugar (TOPS) score of outborn neonates transported with the morbidity and mortality during hospitalization in the neonatal intensive care unit (NICU). Methods Five hundred transported neonates were enrolled in this prospective cohort study by scoring TOPS vitals within an hour of NICU admission, and the outcomes were assessed after 72 hours of hospitalization. Results Among 500 neonates, hypoglycemia, hypoperfusion, hypoxemia, and hypothermia were found in 13%, 32%, 30%, and 37%, respectively. One hundred five (21%) neonates did not survive. Hypoxemia (82%) was the most common parameter, followed by hypoperfusion (78%) among the nonsurvivor neonates. Neonates with a TOPS score of zero survived, whereas neonates with a TOPS score of four had 100% mortality. TOPS SCORE’s overall sensitivity and specificity were reported at 87% and 84%, respectively, with 59% positive and 96% negative predictive values. TOPS score ≥2 had a receiver operating characteristic (ROC) curve at 0.91. Hypoxemia (82%) was the most sensitive parameter to predict mortality, followed by poor perfusion (77%). Conclusion The prognostication of mortality in transported neonates can be assessed by the TOPS score, as mortality notably increases with an increase in the TOPS score. A TOPS score of ≥2 was a good predictor of morbidity and mortality in transported neonates.
Retrospective evaluation of adjuvant capecitabine dosing patterns in triple negative breast cancer
Authors: Lin Kun , Michaels Elena , Polley Eric , O’Donnell Peter H , Howard Frederick M , Hahn Olwen , Fleming Gini F , Nanda Rita , Chen Nan , Yang Heng 
Published: October 2024

Background The CREATE-X trial demonstrated that adjuvant capecitabine was effective in prolonging survival in high-risk triple-negative breast cancer (TNBC) patients. However, the recommended dose is generally not well tolerated by the US population. The goal of this study is to analyze dosing patterns in an ethnically diverse cohort to better characterize tolerability and inform future dosing guidelines. Methods In our single-center retrospective study, we evaluated safety and tolerability in TNBC patients undergoing adjuvant capecitabine treatment. The primary endpoint, relative dose intensity (RDI) across eight cycles, was examined alongside subgroup analyses based on age, race, BMI, and initial dose. Secondary endpoints include capecitabine-related side effects and survival. Results 67 patients who completed adjuvant capecitabine at University of Chicago Medicine (UCM) between January 2017 and November 2022 were eligible. The mean RDI across eight cycles of treatment was 60.2% (95% CI: 0.554–0.650). When compared to the CREATE-X trial, the RDI in our population was significantly lower (0.602 vs. 0.787, p < 0.001). There was no statistically significant difference in average RDI across eight cycles for patients stratified by age, BMI, race, or initial starting dose. The most frequently reported adverse events were hand-foot syndrome (73%), diarrhea (27%), and fatigue (22%), consistent with prior studies. Conclusions Our data demonstrates that a significant portion of patients have a lower tolerated dose of capecitabine in comparison to the recommended adjuvant dose. Acknowledging the limitations of our single-center analysis, RDI was not significantly affected by age, race, BMI, or initial starting dose.
The one-minute sit-to-stand test: A practical tool for assessing functional exercise capacity in patients with COPD in routine clinical practice
Authors: Mellaerts Paulien , Demeyer Heleen , Blondeel Astrid , Vanhoutte Tim , Breuls Sofie , Wuyts Marieke , Coosemans Iris , Claes Lode , Vandenbergh Nele , Beckers Kaat , Bossche Lucas Vanden , Stylemans Dimitri , Janssens Wim , Everaerts Stephanie , Troosters Thierry 
Published: October 2024

Background: Chronic obstructive pulmonary disease (COPD) is associated with a reduced exercise capacity. Although several field tests for exercise capacity have been modified for non-standard settings, i.e. outside the hospital clinic or pulmonary rehabilitation center, their uptake remains limited. Objectives: To assess the test-retest reliability, constuct validity and responsiveness of the one-minute sit-to-stand test (1′STST) adopted in clinical practice among patients with COPD and to confirm the earlier established minimal important difference (MID) of three repetitions. Methods: Patients with COPD performed two 1′STSTs, two 6-minute walk tests (6MWT), an isometric quadriceps force (QF) measurement, a cardiopulmonary exercise test (CPET), and a seven-day physical activity (PA) measurement before and after three months of pulmonary rehabilitation (PR). An Intraclass Correlation Coefficient (ICC) evaluated the agreement between two 1′STSTs. Pearson Correlation examined the association between the 1′STST and other physical measurements, and their changes following PR. A receiver operating characteristic (ROC) curve was constructed using a 30-meter increment in the 6MWT as cut-off to identify responders. Results: The 1′STST demonstrated good reliability (Δ0.9 ± 4.0 repetitions, p = .13; ICC = 0.79). The 1′STST was moderately correlated with the 6MWT (r = 0.57, p < .0001), VO2max (r = 0.50, p = .0006) and maximal work rate (r = 0.52, p = .0003). Weak correlations were observed with QF (r = 0.33, p = .03) and step count (r = 0.38, p = .013). The 1′STST improved after PR (∆ = 3.6 ± 6.4 repetitions, p = .0013) and changes correlated moderately with changes in the 6MWT (r = 0.57, p = .002), QF (r = 0.48, p = .003) and VO2max (r = 0.41, p = .014). A cut-off of three repetitions demonstrated a 71% accuracy in identifying responders to a rehabilitation program. Conclusion: The 1′STST is a valuable alternative to evaluate exercise capacity in patients with COPD when more expensive and time-consuming tests are unavailable.
Implementing creative dance activities for primary school children to improve health and wellbeing: a qualitative study in the North East England
Authors: van der Graaf P , Azevedo L , El Zerbi C , Landindome PN , Watson P 
Published: October 2024

Aims: Evidence suggests that group arts activities with children build resilience and positive mental wellbeing. However, insufficient attention has been paid to how such activities can be implemented in practice across different contexts, particularly in socio-economically disadvantaged areas. Therefore, we explored the implementation of a dance-based intervention in two primary schools situated in an area of high economic deprivation in North East England. Methods: Our study explored Year 1 (age 5–6) and Year 5 (age 9–10) children, their parents, teachers and dance artists’ views of a creative dance intervention (South Tees Arts project; STAR) in two schools in North East England, using interviews and focus groups, combined with innovative data capture activities (i.e. movement activities, graffiti walls, songs and Vox Pops). Results: Children felt that STAR contributed positively to their emotional wellbeing and physical health. Teachers noticed improved confidence, engagement, literacy, and social and motor skills and less disruptive behaviour in class. Benefits continued beyond school, with children exercising at home to practice their dance moves. Several implementation barriers were identified ranging from limited time, large classes, dealing with challenging behaviours, the impact of COVID-19, stigma and anxiety. In response to these challenges, several solutions were developed during project delivery, such as artists and children working in pairs and role modelling by teachers and dance artists. Conclusions: We found three underlying mechanisms for successful implementation: (1) constant communication between teachers, dance artists and parents was essential to managing challenging behaviours, building personal relationships with children, and helping parents to get involved and support their children at home. (2) Linking dance activities to the school curriculum (using narratives from existing reading schemes) helped to support skill gaps. (3) A strong ethos of partnership between school, dance and arts providers and researchers ensured the adaptability and flexibility of projects.
Prognostic value of immune-inflammatory and nutrition indicators in non-metastatic nasopharyngeal carcinoma with negative plasma Epstein–Barr virus DNA
Authors: Weng Youliang , Wu Lishui , Li Ying , Wang Jing , Wu Zijie , Hong Xinyi , Liu Xiaoyong , Lai Jinghua , Lu Jun , Qiu Sufang 
Published: October 2024

Background: Plasma Epstein–Barr virus (EBV) DNA has been identified as a significant prognostic marker for nasopharyngeal carcinoma (NPC), yet there is limited research on the prognosis of NPC patients with negative EBV DNA. Objectives: We explore the prognostic value of comprehensive immune-inflammatory and nutritional indicators to offer personalized treatment recommendations and prognosis predictions for non-metastatic NPC patients with negative EBV DNA. Design: This was a retrospective study. Methods: This study retrospectively analyzed 257 non-metastatic NPC patients with negative EBV DNA between January 2015 and December 2019. The Kaplan–Meier survival curves evaluated survival endpoints, and group discrepancies were assessed with log-rank tests. Principal component analysis (PCA) reduced data dimensionality. Univariate and multivariate Cox regression analyses identified significant prognostic variables. Risk stratification was performed based on recursive partitioning analysis (RPA). A robust prognostic model was constructed by nomogram and evaluated by calibration curves, decision curves, and the time-dependent area under the curve analysis. Results: PCA was employed to compute the immune-inflammation index (III) and nutrition index (NI). Multivariate Cox regression analysis revealed lactate dehydrogenase, III, and NI as significant prognostic variables for overall survival (OS). Utilizing RPA, we stratified the risk into three categories: low-risk group (low III + high NI), middle-risk group (low III + low NI), and high-risk group (high III). Both the middle- ( p = 0.025) and high-risk groups ( p < 0.001) exhibited poorer OS compared with the low-risk group. The nomogram model exhibited superior predictive accuracy compared to tumor lymph node metastasis stage alone (C-index: 0.774 vs 0.679). Conclusion: Our study validated the prognostic significance of III and NI in non-metastatic NPC patients with negative EBV DNA. Additionally, a clinical risk stratification was constructed to offer valuable insights into the individualized treatment of these patients.
Feasibility of an exergaming training program in type 2 diabetes mellitus: A mixed method study
Authors: Savic Nikola , Petry Heidi , de Bruin Eling D. , Lehmann Roger , Eggenberger Patrick , Adcock Manuela , Hirschmann Ruth , Knols Ruud H. 
Published: October 2024

Introduction Individuals with Type 2 Diabetes Mellitus may benefit from exergaming training. Exergaming, technology-driven physical activities requiring participants to be physically active or exercise to play the game, allows combining cognitive with motor training. This trial aimed to primarily evaluate the feasibility of an exergame-based training protocol. Secondarily, possible effects on physical, functional, and patient-reported outcomes were explored. Methods Type 2 diabetic individuals performed an exergaming protocol on a pressure sensitive platform. After a 6-week control period, training was administered 2–3 times weekly for another six weeks for 30–60 minutes per session. Outcome variables were assessed during baseline (T0), pre-intervention (T1) and twice at postintervention (T1 and T2). An interview after completion ended the study program. Feasibility was determined by recruitment, adherence, compliance, attrition rates, motivation, satisfaction, and technology acceptance. Results Eleven of 13 participants completed the study protocol. The feasibility criteria adherence-mandatory (86.4%), adherence-voluntary (70.2%), compliance (99.7%), attrition (15.4%) rate, motivation (82%), satisfaction (80%), and technology acceptance (62.5%) were all deemed acceptable, except for the recruitment rate (13.7%). There were inconsistent effects on functional outcomes, appraisal of diabetes, and health-related quality of life. Qualitative patient-reported experience was overall positive, which is in line with the quantitative results. Conclusion The exergame-based training program is feasible and safe and type 2 diabetic participants’ acceptance of this approach was high, although the recruitment procedure needs minor changes. Furthermore, results were obtained that might be useful in selecting appropriate assessments and sample sizes in future trials.
Mental health provider and youth service users’ perspectives regarding implementation of a digital mental health platform for youth: A survey study
Authors: Hews-Girard Julia , Bright Katherine , Barker Marianne , Bassi Emily M , Iorfino Frank , LaMonica Haley M , Moskovic Karen , Fersovitch Melanie , Stamp Leanne , Gondziola Jessica , Hickie Ian , Dimitropoulos Gina 
Published: October 2024

Background For youth and young adults (YYAs) with mental health concerns, digital mental health (dMH) can improve access to care and support collaboration with providers. Measurement-based care using a dMH platform may further optimize YYA outcomes by individualizing treatment approaches. Engaging service providers and YYA provides an opportunity to better understand how to mitigate implementation challenges. Aim Explore the experiences of mental health care providers and YYAs regarding the implementation of a dMH platform for YYAs accessing mental health care in multiple care settings. Methods Mental health care providers and YYA service users completed an electronic survey exploring their experiences and perceptions of implementing a dMH platform. Survey design, data analysis, and reporting were informed by the Consolidated Framework for Implementation Research (CFIR). Results A total of 195 individuals (100 providers, 95 YYAs) responded. Of those, 48 providers and 79 YYAs reported using the platform at least once. Both groups identified several important factors supporting implementation including collaborative relationships between providers and YYAs, the ability to monitor mental health outcomes, and increased YYA engagement in care. The need for increased provider training and automatic reminders for YYAs to use the platform were common barriers. Each group perceived the other to be uninterested in using the platform, highlighting the importance of using all stakeholder views to inform implementation planning. Conclusions Successful implementation of dMH for care of YYA requires ongoing, user-informed training, integration into existing workflows, and alignment with YYA priorities for care. Future work exploring provider and youth perceptions of the others’ “buy-in” is needed to inform future implementation strategies.
Surgical Closure of Multiple Muscular Ventricular Septal Defects in Children Using 3D-Printed Models
Authors: Andugala Shalom , Grant Caroline , Powell Jennifer , Marathe Supreet , Venugopal Prem , Alphonso Nelson 
Published: October 2024

Background Multiple muscular ventricular septal defects (VSDs) are often difficult to visualize and access surgically. The main challenge is identifying all defects intraoperatively, without which residual defects are inevitable. Patient-specific three-dimensional (3D) printed models can help accurately demonstrate intracardiac anatomy. We present our experience using this technology to surgically close multiple muscular VSDs . Methods Data of all patients with multiple VSDs in whom a 3D-printed model was used to aid surgical planning between September 2021 and July 2023 was collected retrospectively. Our approach involved generating a 3D model from a preoperative computerized tomography scan for each patient, which was then used to precisely identify the location of the multiple VSDs and plan surgical intervention. Results Six patients underwent closure of multiple VSDs using a 3D model. The mean age at surgery was 3.5 years (SD ± 2.8 years). Five (83.3%) patients had previously undergone pulmonary artery banding. The VSDs were approached through the right atrium in three (50%) and the right ventricle in three (50%) patients. Mean cardiopulmonary bypass and myocardial ischemia times were 185.2 min (SD ± 94.8 min) and 147.5 min (SD ± 86 min), respectively. There was no postoperative heart block or a hemodynamically significant residual VSD. All six patients had normal biventricular function at a median follow-up duration of 1.7 months (interquartile range: 1.2-7.4 months). Conclusion 3D printing to aid closure of multiple VSDs is safe, reliable, and reproducible. We recommend adding 3D printing to surgeons’ armamentarium when faced with the challenge of closing multiple muscular VSDs in children.
Management of a Dual Low Sodium and Diabetic Diet by Patient-Caregiver Dyads: A Qualitative Descriptive Study
Authors: DeNotto Leigh Anne , Chung Misook L. , Key Kaitlin Voigts , Mudd-Martin Gia 
Published: October 2024

Purpose The purpose of the study was to explore factors surrounding management of simultaneous dietary recommendations for heart failure and type 2 diabetes among patient-caregiver dyads. Methods Qualitative description was used to explore dyad experiences managing a dual diet. Semi-structured interviews were conducted with patients with a concurrent diagnosis of type 2 diabetes and heart failure and their family caregiver. Each 60-minute interview was conducted virtually. Interviews were audio recorded and transcribed verbatim. Thematic analysis was conducted with coding used for themes at dyadic-and individual levels. Results Twelve patient-caregiver dyads (N = 24) were interviewed. The mean age was 57 years (±15 years). Most participants were white (75%); patients were predominantly male, and caregivers were predominantly female (83.3% for both). Dyadic-level themes that emerged included factors that influence simultaneous management of dual diet recommendations. Themes included shared barriers, facilitators, motivators, and strategies for dual diet management. Individual-level themes discussed by patients were barriers and motivators to dual diet management, and caregivers discussed barriers to supporting dual diet management. Conclusions Findings from the study highlight that patients and caregivers often work together and share similar barriers, facilitators, motivators, and strategies for adhering to a dual diet. The results provide insight into chronic disease management at the family level and can guide health care providers’ efforts to promote family involvement with dietary recommendations for patients with multiple comorbidities.
You’ll never seek alone: The impact of active labour market policies on finding a job
Authors: Arranz José María , García-Serrano Carlos 
Published: October 2024

AbstractUsing the administrative records of the Spanish Public Employment Service for the period 2018–2019, we analysed the impact of participation in job search assistance and training programmes on the chances of unemployed jobseekers finding employment, as well as the quality of the job obtained. Propensity score matching techniques were used to evaluate the effectiveness of these programmes. We found that participation exerted a positive and significant differential effect on the probability of transition from unemployment to employment and on the probability of finding a job of intermediate quality compared to non-participation. This positive impact was largely due to the effect of training programmes, the magnitude of which persisted even as the period elapsed between participation and exit towards employment increased, whereas job search assistance was less effective over time. The positive influence of participation appeared to be more intense for specific socioeconomic groups.