bluuebunny/crossref_metadata_2025_split huggingface dataset:
The curation of Arachnida collections in alcohol: An international survey
Authors: Beccaloni Janet 
Published: January 2017

Abstract
The Natural History Museum, London (NHMUK), has a large Arachnida collection in alcohol. Although the NHMUK follows best-practice in alcohol collections standards, there are still standards that have yet to be agreed upon, e.g., the choice of optimum printer and ink for producing labels. In 2012, I designed a survey to establish how alcohol collections are curated in other institutions around the world. I sent a questionnaire relevant to all collection sizes, materials, and storage spaces to 49 institutions in 36 countries. Responses from 42 institutions indicated: (1) collection size did not determine specific procedure; (2) museums with the largest collections are not restricted to one geographic region; (3) funding was the primary determinant of equipment and storage method, which sometimes resulted in unsuitable conditions; (4) although some methods were similar (e.g., use of ethanol), factors such as materials and equipment among other issues varied widely; (5) several issues are universal, and further research and the development of standards are needed. The results will be used to inform the establishment of further standards at the NHMUK and may also be a useful source of information for other institutions with alcohol collections. Current and future work on collection standards at the NHMUK is discussed.
3D shape measurement with thermal pattern projection
Authors: Brahm Anika , Reetz Edgar , Schindwolf Simon , Correns Martin , Kühmstedt Peter , Notni Gunther 
Published: January 2017

Abstract
Structured light projection techniques are well-established optical methods for contactless and nondestructive three-dimensional (3D) measurements. Most systems operate in the visible wavelength range (VIS) due to commercially available projection and detection technology. For example, the 3D reconstruction can be done with a stereo-vision setup by finding corresponding pixels in both cameras followed by triangulation. Problems occur, if the properties of object materials disturb the measurements, which are based on the measurement of diffuse light reflections. For example, there are existing materials in the VIS range that are too transparent, translucent, high absorbent, or reflective and cannot be recorded properly. To overcome these challenges, we present an alternative thermal approach that operates in the infrared (IR) region of the electromagnetic spectrum. For this purpose, we used two cooled mid-wave (MWIR) cameras (3–5 μm) to detect emitted heat patterns, which were introduced by a CO2 laser. We present a thermal 3D system based on a GOBO (GOes Before Optics) wheel projection unit and first 3D analyses for different system parameters and samples. We also show a second alternative approach based on an incoherent (heat) source, to overcome typical disadvantages of high-power laser-based systems, such as industrial health and safety considerations, as well as high investment costs. Thus, materials like glass or fiber-reinforced composites can be measured contactless and without the need of additional paintings.
In vitro modelling of familial amyloidotic polyneuropathy allows quantitative detection of transthyretin amyloid fibril-like structures in hepatic derivatives of patient-specific induced pluripotent stem cells
Authors: Hoepfner Jeannine , Kleinsorge Mandy , Papp Oliver , Alfken Susanne , Heiringhoff Robin , Pich Andreas , Sauer Vanessa , Zibert Andree , Göhring Gudrun , Schmidt Hartmut , Sgodda Malte , Cantz Tobias 
Published: January 2017

AbstractThe transthyretin protein is thermodynamically destabilised by mutations in the transthyretin gene, promoting the formation of amyloid fibrils in various tissues. Consequently, impaired autonomic organ function is observed in patients suffering from transthyretin-related familial amyloidotic polyneuropathy (FAP). The influence of individual genetic backgrounds on fibril formation as a potential cause of genotype-phenotype variations needs to be investigated in order to ensure efficient patient-specific therapies. We reprogrammed FAP patient fibroblasts to induced pluripotent stem (iPS) cells and differentiated these cells into transthyretin-expressing hepatocyte-like cells (HLCs). HLCs differentiated from FAP iPS cells and healthy control iPS cells secreted the transthyretin protein in similar concentrations. Mass spectrometry revealed the presence of mutant transthyretin protein in FAP HLC supernatants. In comparison to healthy control iPS cells, we demonstrated the formation of transthyretin amyloid fibril-like structures in FAP HLC supernatants using the amyloid-specific dyes Congo red and thioflavin T. These dyes were also applicable for the quantitative determination ofin vitroformed transthyretin fibril-like structures. Moreover, we confirmed the inhibition of fibril formation by the TTR kinetic stabiliser diclofenac. Thioflavin T fluorescence intensity measurements even allowed the quantification of amyloid fibril-like structures in 96-well plate formats as a prerequisite for patient-specific drug screening approaches.
It’s (Still) About Time
Authors: Turnheim Tina 
Published: January 2017

Abstract

The article examines analogies in the ways in which the culture industry, (star) commodities and financial products (such as derivatives) are shaping the imaginaries of the future in the present. Against the backdrop of the excitement about 21st of October, which became “ Back to the Future-Day” in 2015, and the announcement of the Nike MAG sneaker-launch, I seek to analyse whether and to what extent this projection of futurity on a commodity known from product placement in a blockbuster could be understood as a symptom for a deeper lack of futurity.
Effects of ulinastatin on global ischemia via brain pro-inflammation signal
Authors: Jiang Xiao-Ming , Hu Jing-Hai , Wang Lu-Lu , Ma Chi , Wang Xu , Liu Xiao-Liang 
Published: January 2017

Abstract
Ulinastatin [urinary trypsin inhibitor (UTI)] plays an important role in the protection of organs against ischemic injury during severe inflammation. The purposes of this study were to examine the effects of UTI on the levels of pro-inflammatory cytokines (PICs) and protein expression of PIC receptors in the neocortex and hippocampus CA1 region of rats after transient global ischemia induced via cardiac arrest (CA). Specifcally, interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) were analyzed. CA was induced by asphyxia followed by cardiopulmonary resuscitation in rats. ELISA and western blot analysis were employed to determine PICs and their receptors in the neocortex and hippocampus. Our results show that IL-1β, IL-6 and TNF-α were significantly elevated in the neocortex and hippocampal CA1 field after CA. This was accompanied with an increase in PIC receptors, namely IL-1R, IL-6R and TNFR1. Systemic injection of UTI attenuated the amplification of PIC signal pathways in these brain regions. UTI also improved the modified Neurological Severity Score and brain tissue edema in CA rats. Notably, UTI resulted in an increase in survival of CA rats as compared to CA rats without treatment. In conclusion, UTI plays a beneficial role in modulating transient global ischemia induced by CA by altering PIC signal mechanisms, but further studies are needed to draw more firm conclusions.
Early commitment and robust differentiation in colonic crypts
Authors: Tóth Beáta , Ben‐Moshe Shani , Gavish Avishai , Barkai Naama , Itzkovitz Shalev 
Published: January 2017

AbstractTissue stem cells produce a constant flux of differentiated cells with distinct proportions. Here, we show that stem cells in colonic crypts differentiate early to form precisely 1:3 ratio of secretory to absorptive cells. This precision is surprising, as there are only eight stem cells making irreversible fate decisions, and so large stochastic effects of this small pool should have yielded much larger noise in cell proportions. We use single molecule FISH, lineage‐tracing mice and simulations to identify the homeostatic mechanisms facilitating robust proportions. We find that Delta‐Notch lateral inhibition operates in a restricted spatial zone to reduce initial noise in cell proportions. Increased dwell time and dispersive migration of secretory cells further averages additional variability added during progenitor divisions and breaks up continuous patches of same‐fate cells. These noise‐reducing mechanisms resolve the trade‐off between early commitment and robust differentiation and ensure spatially uniform spread of secretory cells. Our findings may apply to other cases where small progenitor pools expand to give rise to precise tissue cell proportions.
О литературе и любви (Цыпкин. Лето в Бадене)
Authors: Бержайте Дагне 
Published: January 2017

Leonidas Cypkinas rusų skaitytojams tapo žino­mu tik praėjus kiek daugiau nei dvidešimt metų po jo mirties, kai 2003 m. rusų kalba pasirodė iki tol tik Vakarų auditorijai plačiai žinomas jo romanas Vasara Badene. Knygą apie vieną žymiausių rusų rašytojų Fiodorą Dostojevskį, paremtą rašytojo žmonos Anos Grigorjevnos Dienoraščiais bei jos Prisiminimais, autoriaus tėvynėje išgarsino ameri­kiečių rašytoja, filosofė ir eseistė Siuzan Zontag, pri­stadydama ją kaip vieną geriausių, literatūriškiausių XX amžiaus tekstų. Šiame straipsnyje, pasitelkus tiek Zontag, tiek kitų tyrėjų nuomones, siekiama parodyti, kad dauguma jų visų pirma išryškino ats­kiras, dažnai publicistines romano tendencijas, ne visada atsižvelgdami į romano visumą, į tai, apie ką rašė dar J. Lotmanas, jog pokalbis apie kūrinio idėją neatskiriamas nuo pokalbio apie jo meninę struk­tūrą. Straipsnio autorė šį kartą siūlo kiek atidžiau pažvelgti į romano pavadinimą, kuriame, jos nuo­mone, galima aptikti akivaizdžias kito rusų rašytojo I. Turgenevo kūrybos aliuzijas, leidžiančias teigti, kad vis tik Cypkino romane Vasara Badene svar­biausia – ne taip visus suintrigavusi Dostojevskio ir žydų problema, o meilės ir pareigos konfliktas; ro­mano ašis – Dostojevskio žmonos pasiaukojančios meilės savo vyrui istorija, kuri tam tikru aspektu galėtų būti gretinama su rašytojo Cypkino jausmais didžiajam rusų klasikui.
A concepção fenomenológica de verdade como elemento motivador da “virada idealista” husserliana
Authors: Missaggia Juliana 
Published: January 2017

Este artigo analisa o papel da concepção fenomenológica de verdade para a chamada “virada idealista” no pensamento husserliano. Embora normalmente não se leve em consideração a noção de verdade como elemento motivador nessa transformação da fenomenologia, pretendo demonstrar que se trata de uma das razões centrais para tal modificação. Para tanto, analiso também uma série de questões fundamentais para a compreensão do conceito de verdade na fenomenologia de Husserl, muitas vezes causadoras de interpretações equivocadas: as noções de intenção significativa, intenção intuitiva e evidência; a originalidade de tais conceitos em relação à concepção de verdade como correspondência e os diferentes tipos de verdade no pensamento husserliano, os quais mantêm uma coerência interna a despeito de suas particularidades.
Relativistic ontological realism
Authors: Costa Antônio Carlos da Rocha 
Published: January 2017

The paper introduces the concept of relativistic ontological realism, and the corresponding notion of relativistic realization of objects. The conditions that allow for the relativistic realization of objects are determined. In particular, the paper indicates the way the imposition of organizational structures on already existent objects supports the relativistic realization of new, more complex ones. A type-theoretic presentation of the principles of relativistic ontological realism is given in the language of predicate calculus, making use of the notion of typed world and the condition of effectiveness in the determination of the existence of objects. Two case studies illustrating the way the notion of relativistic ontological realism supports ontological analysis are presented, both concerning the ontology of computations, more specifically, the relativistic realization of computational levels in computational systems. The first case study deals with the realization of logical circuits through structural arrangements of electrical circuits. The second, with the realization of software systems through computer programming. A conception of the mechanics of the relativistic realization of objects, taking the imposition of organizational structures on previously extant objects as its basis, is proposed and briefly analyzed.
Vontade de ser máquina: imaginação material em o apocalipse dos trabalhadores
Authors: Minuzzi Luara Pinto , Barros Bruno Mazolini de 
Published: January 2017

Neste artigo, pretendemos analisar o romance o apocalipse dos trabalhadores, do escritor português Valter Hugo Mãe, a partir dos estudos do filósofo Gaston Bachelard sobre a imaginação material. Para isso, o personagem Andriy foi selecionado como foco do estudo: ucraniano, o homem vive uma realidade dura de imigrado em Portugal, trabalhando muito e ganhando pouco, em um sistema exemplar de capitalismo tardio, longe da família e sem amigos. Por isso, ele decide virar máquina e se despir de sua humanidade para não sentir mais – e esse processo de metalização ganha novos significados quando interpretado principalmente à luz da simbologia do elemento terrestre examinado por Bachelard em A terra e os devaneios da vontade.********************************************************************The will to be a machine: material imagination in o apocalipse dos trabalhadoreswriter Valter Hugo Mãe, according with the theory of the philosopher Gaston Bachelar about the “material imagination”. To do this, the analyze will be focused on the character Andriy: Ukrainian, he has a hard life as immigrant in Portugal, working a lot and not getting much from it, in a late capitalism system, far from his family and without friends. Because of this, he decides to become a machine, giving away his own humanity condition: this process of turning himself a metal structure revels subtle meanings when interpreted mainly with the symbolic aspect of the earth element, exanimated by Barchelard in La terre et les rêveries de la volonté.Keywords: Valter Hugo Mãe; o apocalipse dos trabalhadores; Gaston Bachelard; Material imagination
Negação da figura paterna e a fuga de Jéssica no Mercador de Veneza: consciência, vergonha e interioridade
Authors: Ludwig Carlos Roberto 
Published: January 2017

Este artigo discute a relação ambígua e dissimulada de Jéssica para com a figura paterna Shylock, no Mercador de Veneza. A fuga de Jéssica e a negação da figura paterna são perpassadas por espasmos de consciência e vergonha, sugerindo que ambas são traços sobredeterminantes da interioridade de Jéssica. A linguagem dos diálogos de Jéssica e Lorenzo sugere que seu amor é provavelmente insincero, pois Jéssica faz insistentemente perguntas duvidando de seu amor, que pode ser movido pela oportunidade de fugir de casa e tomar a fortuna de Shylock. Igualmente, o amor de Lorenzo por Jéssica é enfatizado por conotações carnais e eróticas durante a peça.********************************************************************Denial of the paternal figure and Jessica’s elopement inThe Merchant of Venice: conscience, shame and inwardnessAbstract: This essay discusses Jessica’s ambiguous and deceitful relationship towards her paternal figure Shylock, in The Merchant of Venice. Jessica’s elopement and negation of the paternal figure are pervaded by qualms of conscience and shame, suggesting that both are the over-determining traits of Jessica’s inwardness. The language in Jessica and Lorenzo’s dialogue suggests that their love is probably insincere, once Jessica constantly asks questions doubting their love, which can be motivated by the opportunity to elope and take Shylock’s fortune. Similarly, Lorenzo’s love for Jessica is enhanced by carnal and erotic connotations during the play.Keywords: Conscience; Inwardness; Denial of the Paternal Figure; The Merchant of Venice
Crise da tradição e precariedade contemporânea: inadequação predatória de modelos em A paixão de Amâncio Amaro, de André Laurentino
Authors: Valente Junior Valdemar 
Published: January 2017

Este artigo tem por objetivo detectar elementos da crise contemporânea no âmbito da cultura brasileira, tendo em vista a possibilidade de uma leitura crítica acerca do Nordeste brasileiro a partir de uma análise do romance paixão de Amâncio Amaro, de André Laurentino. Desse modo, a região mais pobre do Brasil insere-se no âmbito de uma prática consumista que se confirma nas formas do capitalismo predatório sem que a isso correspondam possibilidades concretas de ascensão social de sua população. Na obra, inserem-se ainda questionamentos acerca dos conflitos de suas personagens em um cenário de ação marcado por forte atraso. Nesse contexto, vários símbolos da cultura são esvaziados de significado em favor de posturas que os relegam a um plano de inferioridade, no que diz respeito apenas à afirmação de símbolos do consumo alienado.********************************************************************Crisis of the tradition and contemporary precariousness:predatory inadequacy of models in A paixão de Amâncio Amaro, by André LaurentinoAbstract: This article aims to detect elements of the contemporary social crisis within the Brazilian culture, in view of the possibility of a critical reading about the Brazilian Northeast, from an analysis of the novel A paíxão de Amâncio Amaro, by André Laurentino. Thus, the poorest region of Brazil is part of a consumerist practice confirmed in the forms of the predatory capitalism without corresponding concrete possibilities for social advancement of its population. This work also addresses questions about the inner conflicts of their characters in an action scenario marked by strong backwardness. In that context, several symbols of culture lose their meaning in favor of postures that relegate them to an inferior plan, with regard only to the claim symbols of the alienated consumption.Keywords: Contemporary literature; Brazilian Northeast; Consumer society
A Babilônia de cambiáveis jogos identitários: contradição de vozes, estilhaçar de faces
Authors: Prevedello Tatiana 
Published: January 2017

O romance Ontem não te vi em Babilónia, de António Lobo Antunes, ao propor um questionamento sobre a natureza da representação identitária das personagens convida o leitor a refletir a respeito da atividade de criação textual. Nesse âmbito, ao mesmo tempo em que a alteridade dos sujeitos ficcionais passa por um simultâneo processo de afirmação e negação, no qual o “eu” está em constante tensão com o “outro” ou o “não-eu”, a voz narrativa também se apresenta como uma instância criadora vulnerável às instabilidades e limitações decorrentes do trabalho de produção da escrita literária. A proposta da presente reflexão é, portanto, discutir os mecanismos que engendram a hermenêutica da ficção contemporânea, a qual compreende as identidades narrativas como múltiplas, instavéis e em constante processo e (re)elaboração.********************************************************************A Babilônia de cambiáveis jogos identitários:contradição de vozes, estilhaçar de facesAbstract: The novel Didn't see you in Babylon yesterday, by António Lobo Antunes, to propose a question about the nature of identity representation of characters invites the reader to reflect about the activity of textual creation. In this context, while the otherness of fictional individuals are in a simultaneous process of affirmation and negation, in which the “I” is in constant tension between the “other” or “non-self”, the narrative voice is also presented as a creative instance, but susceptible to instabilities and limitations of literary writing work. The purpose of this reflection is, therefore, discuss the mechanisms that engender the hermeneutics of contemporary fiction, which understand the narrative identities as multiple, unstable and in constant process of (re) development.Keywords: Representation; Identity; Otherness; Fiction; Hermeneutics
Uma história de outros regressos: a comunidade lusófona e as fronteiras do império
Authors: Rückert Gustavo Henrique 
Published: January 2017

Neste artigo, pretendemos analisar algumas marcas do hipercontemporâneo nas literaturas de língua portuguesa. Para isso, tomamos a ideia do contemporâneo enquanto as “trevas de nosso tempo”, formulada por Giorgio Agamben. esse sentido, defendemos que as “trevas de nosso tempo” são os problemas relacionados às travessias identitárias das fronteiras da modernidade. Desse modo, analisaremos as obras Estive em Lisboa e lembrei de você, do brasileiro Luiz Ruffato, e O meu nome é Legião, do português Lobo Antunes, as quais representam a questão do imigrante brasileiro e africano em Portugal. Como aporte teórico, utilizaremos conceitos de Homi Bhabha, Stuart Hall, Edward Saïd, João Guimarães Rosa, Boaventura de Sousa Santos e Margarida Calafate Ribeiro. Os resultados apontam que uma hipercontemporaneidade na comunidade lusófona está extremamente relacionada à questão colonial, uma vez que marcas identitárias (língua, nacionalidade, classe social, gênero, religiosidade) são impostas ou reivindicadas a partir das fronteiras que perduram do império.********************************************************************A history of others returns: the Lusophone Community and the borders of the empireAbstract: In this article, we examine some traces of hyper-contemporary in Portuguesespeaking literatures. For this, we take the idea of contemporary as the "darkness of our time", formulated by Giorgio Agamben. In this regard, we argue that the "darkness of our time" are the problems related to identity crossings of the borders of modernity. Thus, we will analyze the works Estive em Lisboa e lembrei de você, by Brazilian Luiz Ruffato, and O meu nome é Legião, by the Portuguese Lobo Antunes, which represent the question of Brazilian and African immigrants in Portugal. As a theoretical contribution, we will use concepts of Homi Bhabha, Stuart Hall, Edward Saïd, João Guimarães Rosa, Boaventura de Sousa Santos and Margarida Calafate Ribeiro. The results indicate that a hyper-contemporaryness in Lusophone community is extremely related to the colonial question, because identifying marks (language, nationality, social class, gender, religiousness) are imposed or claimed from the borders that remain of the empire.Keywords: Hyper-contemporary; Immigration; Empire