bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension
Authors: Rao Rashmi J. , Yang Jimin , Jiang Siyi , El-Khoury Wadih , Hafeez Neha , Okawa Satoshi , Tai Yi Yin , Tang Ying , Aaraj Yassmin Al , Sembrat John , Chan Stephen Y. 
Published: September 2024

AbstractPulmonary arterial hypertension (PAH) is a progressive disease driven by endothelial cell inflammation and dysfunction, resulting in the pathological remodeling of the pulmonary vasculature. Innate immune activation has been linked to PAH development; however, the regulation, propagation, and reversibility of the induction of inflammation in PAH is poorly understood. Here, we demonstrate a role for interferon inducible protein 16 (IFI16), an innate immune sensor, as a modulator of endothelial inflammation in pulmonary hypertension, utilizing human pulmonary artery endothelial cells (PAECs). Inflammatory stimulus of PAECs with IL-1β up-regulates IFI16 expression, inducing proinflammatory cytokine up-regulation and cellular apoptosis. IFI16 mRNA stability is regulated by post-transcriptional m6A modification, mediated by Wilms’ tumor 1-associated protein (WTAP), a structural stabilizer of the methyltransferase complex, via regulation of m6A methylation of IFI16. Additionally, m6A levels are increased in the peripheral blood mononuclear cells of PAH patients compared to control, indicating that quantifying this epigenetic change in patients may hold potential as a biomarker for disease identification. In summary, our study demonstrates IFI16 mediates inflammatory endothelial pathophenotypes seen in pulmonary arterial hypertension.
Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
Authors: Bundalo Maja , Vorlova Sandra , Ulrich Jessica , Barbieri Ruggero , Richter Leon , Höna Leonie , Egg Manuel , Bock Julian , Schäfer Sarah , Solé Núria Amézaga , Rosa Annabelle , Rizzo Giuseppe , Cochain Clemént , Kastenmüller Wolfgang , Henke Erik , Skryabin Boris V. , Rozhdestvensky Timofey S. , Wildgruber Moritz , Lorenz Kristina , Kuhn Michaela , Zernecke Alma 
Published: September 2024

AbstractVascular endothelial growth factors and their tyrosine kinase receptors are key mediators of vasculogenesis and angiogenesis with FLT1 (VEGFR1) serving as a decoy receptor. A truncated mRNA transcript encoding soluble (s) FLT1 can be generated by premature cleavage and polyadenylation (APA). Although a shortening of transcripts is described in pathological settings, including heart diseases, the functional in vivo impact of FLT1 gene isoform generation and relevance for angiogenesis remain unknown. Here, we show that specific splice site mutations within Flt1 inhibit telescripting and activate APA in vivo to efficiently modulate gene isoform expression, inducing a complete loss of full-length (fl) Flt1 and a switch towards sFlt1 in mice. FLT1 is a high-affinity decoy receptor of VEGF limiting vessel overgrowth. We show that sFLT1 was sufficient for developmental vasculogenesis, whereas flFLT1 controlled ischemia-driven angiogenesis. Our results demonstrate that telescripting is essential in vivo for controlling Flt1 isoform expression and angiogenesis and can be harnessed to improve reparative revascularization. Furthermore, given the widespread abundance of APA signals, our approach may serve as a blueprint for studying telescripting and generating other truncated gene isoforms in vivo.
Domain wall dynamics in tungsten trioxide: Evidence for polar domain walls
Authors: Eckstein Jack T. , Yokota Hiroko , Domingo Neus , Catalan Gustau , Aktas Oktay , Carpenter Michael A. , Salje Ekhard K. H. 
Published: September 2024

Domain walls have distinct properties from the bulk, and tailoring them to suit the needs for device applications is critical. Tungsten trioxide, WO3, is of great interest for device applications that make use of domain wall properties; it exhibits a phenomenologically rich sequence of phase transitions, virtually all of which are ferroelastic in character, resulting in many sets of domain walls at low temperatures, each with their own unique properties. Domain wall motion and its contribution to the piezoelectric response have been investigated in WO3 from 300 to 180 K using resonant ultrasound spectroscopy (RUS) and resonant piezoelectric spectroscopy (RPS), which showed that the P21/n,P1¯, and P21/c phases give a piezoelectric response despite the bulk being nominally centrosymmetric. Second harmonic generation (SHG) confirmed that polarity was strongest within the domain walls, and additional weak signals were found in the domains. Domain wall mobility was investigated in the Pbcn,P21/n, and P21/c phases from 685 to 5 K. Domain walls in the P21/n and P1¯ were more mobile than those in the Pbcn and P21/c structures, and soon after the P1¯→P21/c transition the walls become pinned at ∼140K.

Published by the American Physical Society
2024
Exposing the odd-parity superconductivity in
CeRh2As2
with hydrostatic pressure
Authors: Semeniuk K. , Pfeiffer M. , Landaeta J. F. , Nicklas M. , Geibel C. , Brando M. , Khim S. , Hassinger E. 
Published: September 2024

Odd-parity superconductivity is a fundamentally interesting but rare state of matter with a potential for applications in topological quantum computing. Crystals with staggered locally noncentrosymmetric structures have been proposed as platforms where a magnetic field can induce a transition between even- and odd-parity superconducting (SC) states. The strongly correlated superconductor CeRh2As2, with the critical temperature Tc≈0.4K, is likely the first example material showing such a phase transition, which occurs at the magnetic field μ0H*=4T applied along the crystallographic c axis. CeRh2As2 also undergoes a phase transition of an unknown origin at T0=0.5K. By subjecting CeRh2As2 to hydrostatic pressure and mapping the resultant changes to the SC phase diagrams we investigated how the lattice compression and changes to the electronic correlations affect the stability and relative balance of the two SC states. The abnormally high in-plane upper critical field becomes even higher close to a quantum critical point of the T0 order. Remarkably, the SC phase-switching field H* is drastically reduced under pressure, dropping to 0.3 T at 2.7 GPa. This result signals an apparent strengthening of the local noncentrosymmetricity and forecasts a possible stabilization of the putative odd-parity state down to zero field, hitherto not considered by theoretical models.

Published by the American Physical Society
2024
Dark-Sector Search via Pion-Produced
η
and
η′
Mesons Decaying Invisibly in the NA64h Detector
Authors: Andreev Yu. M. , Antonov A. , Ayala Torres M. A. , Banerjee D. , Banto Oberhauser B. , Bernhard J. , Bisio P. , Celentano A. , Charitonidis N. , Cooke D. , Crivelli P. , Depero E. , Dermenev A. V. , Donskov S. V. , Dusaev R. R. , Enik T. , Frolov V. N. , Gertsenberger S. V. , Girod S. , Gninenko S. N. , Hösgen M. , Kachanov V. A. , Kambar Y. , Karneyeu A. E. , Kekelidze G. D. , Ketzer B. , Kirpichnikov D. V. , Kirsanov M. M. , Kolosov V. N. , Kramarenko V. A. , Kravchuk L. V. , Krasnikov N. V. , Kuleshov S. V. , Lyubovitskij V. E. , Marini A. , Marsicano L. , Matveev V. A. , Mena Fredes R. , Mena Yanssen R. G. , Molina Bueno L. , Mongillo M. , Peshekhonov D. V. , Polyakov V. A. , Radics B. , Salamatin K. M. , Samoylenko V. D. , Sieber H. , Shchukin D. A. , Soto O. , Tikhomirov V. O. , Tlisova I. V. , Toropin A. N. , Tuzi M. , Volkov P. V. , Volkov V. Yu. , Voronchikhin I. V. , Zamora-Saá J. , Zhevlakov A. S. ,   NA64 Collaboration
Published: September 2024

We present the first results from a proof-of-concept search for dark sectors via invisible decays of pseudoscalar η and η′ mesons in the NA64h experiment at the CERN SPS. Our novel technique uses the charge-exchange reaction of 50 GeV π− on nuclei of an active target as the source of neutral mesons. The η,η′→invisible events would exhibit themselves via a striking signature—the complete disappearance of the incoming beam energy in the detector. No evidence for such events has been found with 2.9×109 pions on target accumulated during one day of data taking. This allows us to set a stringent limit on the branching ratio Br(η′→invisible)<2.1×10−4 improving the current bound by a factor of ≃3. We also set a limit on Br(η→invisible)<1.1×10−4 comparable with the existing one. These results demonstrate the great potential of our approach and provide clear guidance on how to enhance and extend the sensitivity for dark sector physics from future searches for invisible neutral meson decays.

Published by the American Physical Society
2024
Relationship between Machiavellianism and relational energy: based on trait activation theory
Authors: Sun Yicong , Yan Aimin , Hu Xinfang , Zang Zhimei 
Published: September 2024

PurposeThis study draws on the trait activation theory to investigate the relationship between Machiavellianism and relational energy, considering the mediating role of facades of conformity and the moderating role of leader–member exchange ambivalence.Design/methodology/approachWe collected survey data from 275 employees in central China at three time points. We conducted confirmatory factor analysis and bootstrapping to test the hypotheses using Mplus7.0 and the PROCESS macro.FindingsWe found that facades of conformity mediated the relationship between Machiavellianism and relational energy. Moreover, the indirect effect of Machiavellianism on relational energy via facades of conformity was more significant when leader–member exchange ambivalence is higher.Originality/valueThis study provides empirical evidence of how and when Machiavellians acquire relational energy from leaders.
Communicating sustainability: the Iberian challenge for authorial fashion brands
Authors: Dourado Pedro , LLovet Carmen , Ortega Fernández Eglée 
Published: September 2024

PurposeGiven the potential for authorial fashion to lead the way in the field of sustainable fashion and digital platforms to be a powerful tool for spreading sustainable messages, this study seeks to explore the emphasis given to sustainability in the digital communication of Portuguese and Spanish’s authorial fashion.Design/methodology/approachA thematic analysis of all the posts published on the feeds of the 63 designers who presented their collections at the Madrid and Lisbon fashion weeks in September/October 2022 (Spring/Summer 2023) or February/March 2023 (Fall/Winter 2023/2024) editions was carried out. The information was collected over a six-month period between the two fashion weeks. This study is based on the categories identified in the reflexive thematic analysis developed by Testa et al. (2020). After adapting the categories to our analysis, 14 emerging themes were identified as observation criteria.FindingsA total of 4,699 posts were examined. The analysis reveals a general lack of interest in mentioning sustainability – a subject evident in just around 6% of the content – as well as a high emphasis on the visual aspect of the fashion product. Several similarities between the Portuguese and Spanish markets were observed.Originality/valueThis study is important since there are few cross-cultural studies in the field of fashion between the two countries, particularly on sustainable fashion. Furthermore, it establishes a structure that is easily replicable in various markets and geographical areas.
Can virtual influencers affect purchase intentions in tourism and hospitality e-commerce live streaming? An empirical study in China
Authors: Yu Teng , Teoh Ai Ping , Bian Qing , Liao Junyun , Wang Chengliang 
Published: September 2024

Purpose
This study aims to examine how virtual influencers (VIs) affect purchase intentions in tourism and hospitality e-commerce live streaming (THCLS) by focusing on the roles of VIs’ source credibility, trust in products, trust in VIs, emotional engagement, parasocial relationships and influencer–product congruence.

Design/methodology/approach
Survey data from 416 active viewers of VIs in THCLS were analysed using partial least squares structural equation modelling.

Findings
This study highlights the importance of the VIs’ source credibility, which positively affects trust in the product, trust in VIs and emotional engagement. However, source credibility does not have a positive impact on parasocial relationships. Trust in products positively influences trust in VIs. Emotional engagement and trust in VIs significantly influence parasocial relationships, which, positively affects purchase intentions. Influencer–product congruence strengthens the link between parasocial relationships and purchase intentions but does not moderate the relationship between trust in VIs and purchase intentions. No significant gender differences were observed, although minor discrepancies were noted in the effect of trust in products on trust in VIs. The importance–performance map analysis revealed that parasocial relationships are the most important factor influencing purchase intentions, while influencer–product congruence has the highest performance, trust in products is the least important and VIs’ source credibility has the lowest performance.

Practical implications
This study provides actionable insights for marketers leveraging VIs in the THCLS sector, emphasizing strategies to enhance VI credibility, foster parasocial relationships, ensure influencer–product congruence and adopt gender-neutral marketing approaches to effectively influence purchase intentions.

Originality/value
This study offers theoretical and practical insights into the role of VIs in THCLS, illuminating their impact on consumer behaviour and purchase intentions.
What factors motivate customers to embrace a metaverse hotel?
Authors: Kim Jungsun (Sunny) , Erdem Mehmet , Kim Boran 
Published: September 2024

Purpose
This paper aims to investigate the influence of four motivational elements (i.e. utilitarian, hedonic, social and escapism motivations) on the propensity of customers to utilize a metaverse hotel, as well as whether age, gender and mobility disability play substantial moderating roles in these relationships.

Design/methodology/approach
Data was gathered from 843 US residents who had experienced a hotel stay within the past two years. We tested the hypotheses using structural equation modeling and multigroup analysis.

Findings
The findings indicated that, in both age and gender groups, hedonic, social and escapism motivations had significant effects on intentions to use a metaverse hotel, whereas utilitarian motivation did not. The influence of escapism motivation on customers’ usage intentions was significantly more pronounced for males than females, suggesting the moderating role of gender in this relationship. Hedonic and social motivations exerted significant effects on usage intentions in both mobility disability and non-disability groups. The relationship between escapism motivation and intentions to use was significant for the non-disability group only, suggesting the moderating role of disability in this association.

Practical implications
This research provides recommendations for hotel managers and technology providers aiming to enhance the adoption of metaverse hotels by customers and to augment the worth of this technology.

Originality/value
This research fills the voids in the current literature by formulating and empirically evaluating a research framework to gain deeper insights into the motivations that drive the acceptance of a metaverse hotel.
Application of Flores model considering variable recovery coefficient in dynamics analysis of ball bearings
Authors: Liu Zhe , Zhang Wenjing , Guo Zhen , Yang Fang , Liu Heng , Chen Wei 
Published: September 2024

Purpose
This paper aims to select an appropriate contact force model and apply it to the interaction model between the balls and the cage in the rolling bearings to describe the elastic–plastic collision phenomena between the two.

Design/methodology/approach
Taking the ball–disk collision mode as an example, several main contact force models were compared and analyzed through simulation and experiment. In addition, based on the consideration of yield strength of materials and initial collision velocity, a variable recovery coefficient model was proposed, and its validity and accuracy were verified by the ball–disk collision experiments. Then, respectively, the Flores model and the Hertz model were applied to the interaction between the balls and the cage, and the dynamics simulation results were compared.

Findings
The results indicate that the Flores model has good regression of recovery coefficient, indicating good applicability for both elastic and elastic–plastic contacts and can be applied to the contact collision situations of various materials. Under certain working conditions, there are significant differences in the dynamics results of rolling bearings simulated using the Flores model and Hertz model, respectively.

Originality/value
This paper applies the Flores model with variable recovery coefficients to the dynamics simulation analysis of ball bearings to solve the elastic–plastic collision problem between the rolling elements and the cage that cannot be reasonably handled by the Hertz model.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-04-2024-0138/
Study on the wear characteristics of cylindrical needle bearings on the crankshaft of RV decelerator
Authors: Xia Xiaotian , Han Ju 
Published: September 2024

Purpose
The purpose of this study is to systematically analyze the wear of cylindrical needle bearings in rotary vector reducers under temperature rise and identify the influencing factors.

Design/methodology/approach
Based on the dynamic characteristics of the RV-20E reducer, the time-varying contact force of the cylindrical needle bearing and the entrainment speed of the inner and outer raceways were calculated. A mixed elastohydrodynamic lubrication model of the needle bearing, considering friction and temperature rise, was established using a dynamic rough tooth surface model. The model solved for the oil film thickness, contact stress and wear conditions of the bearing raceway contact area. The effects of the number of rolling needles, the diameter of rolling needles and surface strength on the wear characteristics were analyzed.

Findings
The results of this study show that the oil film thickness, oil film pressure and surface scratches of cylindrical needle bearings exhibit an uneven, patchy distribution under the combined effects of friction and temperature rise. When the radius of the rolling needle is less than 1.44 mm, inner ring wear is less than outer ring wear. Conversely, when the radius exceeds 1.44 mm, inner ring wear is greater. The optimal rolling needle radius is 1.6 mm. Increasing the number of rolling needles and enhancing the yield strength of the contact surface significantly extend bearing life.

Originality/value
This study provides valuable recommendations for optimizing bearing structural parameters and material characteristics in the design of rotary vector reducers.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-07-2024-0242/
A conceptual model for tracking the provenance of activities in knowledge organization systems
Authors: Choi Inkyung , Cheng Yi-Yun 
Published: September 2024

PurposeThe purpose of this study is to develop a conceptual model, ProvKOS, for tracking the provenance of change activities in a knowledge organization system (KOS). By extending current provenance practices, this model represents dynamic changes in a KOS more effectively.Design/methodology/approachWe take a five-step approach to develop the conceptual model, including content analysis of KOS editorial data, environmental scan of existing provenance models, development of persona-specific provenance questions and a participatory design with stakeholders to ensure the model’s utility.FindingsWe introduce (1) a taxonomy of editorial activities for a KOS; (2) a conceptual model ProvKOS, which extends existing models PROV and Simple Knowledge Organization Systems (SKOS). We also provide detailed data dictionaries for the entities, activities and warrants classes proposed in the model. A use case on “gender dysphoria” in Dewey Decimal Classifications (DDCs) is provided to illustrate the implementation of ProvKOS. This shows ProvKOS’s ability to capture KOS changes effectively and to link external resources relating to the changes.Research limitations/implicationsFurther validation may be needed to implement the ProvKOS model across various types of KOSs.Practical implicationsProvKOS can help improve machine readability, querying and analysis of a KOS. Especially within the linked data environment, the enhanced provenance documentation through ProvKOS can enable a network of KOSs, which will then inform better linked data or knowledge graph designs.Social implicationsBy facilitating better tracking of changes within a KOS and across KOSs, ProvKOS can enhance the accessibility and usability of knowledge bases across different cultural and social contexts, thus better supporting inclusive information practices.Originality/valueThe proposed model is novel in two ways: one, its ability to represent dynamic change activities in a KOS, which has not been discussed anywhere else; two, it supports the interconnectivity across KOSs by providing a “warrant” class to substantiate the context of changes.
Partnering through pandemic recovery: an examination of a research-practice partnership in Guilford County Schools
Authors: Hashim Ayesha , Davison Miles , Morton Emily , Leak James , Wright J. Clark , Dizon-Ross Elise , Stephens Sonya , Hamilton Kara 
Published: September 2024

PurposeThe Elementary and Secondary School Emergency Relief (ESSER) requires districts to deliver “evidence-based interventions” to students impacted by the pandemic. The policy has created a unique opportunity for researchers and practitioners to engage with evidence to learn how recovery interventions work and under what conditions.Design/methodology/approachThis study is part of a research-practice partnership (RPP) between Guilford County Schools, AIR-CALDER, Harvard University and NWEA to understand the impacts and implementation of ESSER-funded recovery programs. We use a case analysis approach and frameworks of evidence-use and RPPs to explain how researchers and Guilford leaders engage with evidence to improve and evaluate programs.FindingsThe RPP used evidence to inform Guilford leaders’ recovery approaches and strengthened researchers’ evaluations of programs. Conditions that enabled evidence engagement included the RPP’s goals, research activities and collaborative conditions such as boundary spanning activities, team meetings, relationships and trust. We also observed factors that hindered evidence engagement, including the RPP’s nascent stage, structure and breadth of goals, rapid policy timelines and other organizational conditions in Guilford.Originality/valueGiven the complexities of pandemic recovery, RPPs can help researchers evaluate programs in their local context, and present evidence in ways that are actionable to guide decision-making. District leaders can play a valuable role in co-designing research studies attuned to local priorities and context and facilitating research participation among internal stakeholders. However, newly formed RPPs with broad goals for impact will need more time and resources to build an improvement infrastructure for sustaining pandemic recovery.