bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosis of endometriotic lesions by sonovaginography with ultrasound gel
Authors: Brătilă Elvira , Comandaşu Diana Elena , Coroleucă Ciprian , Cîrstoiu Monica Mihaela , Berceanu Costin , Mehedintu Claudia , Bratila Petre , Vladareanu Simona 
Published: December 2016

Aims: The aim of the study was to evaluate the diagnostic ability of sonovaginography (SVG) with ultrasound gel in patients with endometriosis. Material and methods: We conducted a multicentre prospective study, which included 193 patients with symptoms highly suggestive for endometriosis. All patients were investigated by transvaginal sonography and SVG with gel and afterwards underwent laparoscopic surgery. For each category of endometriotic lesions investigated, we calculated and compared the sensitivity, specificity, positive predictive value and negative predictive value of the imagisticinvestigations used. Results: In the case of endometriotic lesions of the uterosacral ligaments, SVG with gel had a sensitivity of 78.5% and a specificity of 96% (p=ns). The lesions of the vagina and rectovaginal septum were diagnosed with a sensitivity of 79%, respectively 94% (p=ns), obtaining a specificity of 99%, respectively of 97% (p=0.007). The lesions of the Douglas pouch were identified with a sensitivity of 81% (p=0.015), and those of the rectosigmoid with a 94% sensitivity (p=0.010). We obtained lower sensitivity (67%) in detecting the lesions of the urinary bladder (p=ns). Conclusions: SGV with ultrasound gel represents a useful investigation tool for the evaluation of endometriotic lesions in the posterior pelvic compartment.
Unusual multiple metastatic localisations in adult Burkitt’s lymphoma. A case report.
Authors: Nagy Georgiana , Chira Romeo , Crisan Doinita , Munteanu Mihai , Mircea Petru Adrian 
Published: December 2016

Burkitt’s lymphoma is an aggressive B-cell non-Hodgkin lymphoma. It is less common in adults accounting for less than 5% of non-Hodgkin lymphoma cases. Radiological methods (ultrasonography, computed tomography) are indispensable for the initial evaluation and appreciation of organ extension; complete diagnosis is confirmed by the histopathological examination.We present the clinical case and ultrasound imaging particularities of a young patient diagnosed with multisystem involvement Burkitt’s lymphoma, with rapid progressive evolution towards exitus.
Improvement of Ice Hockey Players’ On-Ice Sprint With Combined Plyometric and Strength Training
Authors: Dæhlin Torstein E. , Haugen Ole C. , Haugerud Simen , Hollan Ivana , Raastad Truls , Rønnestad Bent R. 
Published: December 2016

Background:Combined plyometric and strength training has previously been suggested as a strategy to improve skating performance in ice hockey players. However, the effects of combined plyometric and strength training have not previously been compared with the effects of strength training only.Purpose:To compare the effects of combined plyometric and strength training on ice hockey players’ skating sprint performance with those of strength training only.Methods:Eighteen participants were randomly assigned to 2 groups that completed 5 strength-training sessions/wk for 8 wk. One group included plyometric exercises at the start of 3 sessions/wk (PLY+ST), and the other group included core exercises in the same sessions (ST). Tests of 10- and 35-m skating sprints, horizontal jumping, 1-repetition-maximum (1 RM) squat, skating multistage aerobic test (SMAT), maximal oxygen consumption, repeated cycle sprints, and body composition were performed before and after the intervention.Results:The participants increased their 1RM squat, lean mass, and body mass (P < .05), with no difference between the groups. Furthermore, they improved their 3×broad jump, repeated cycle sprint, and SMAT performance (P < .05), with no difference between the groups. PLY+ST gained a larger improvement in 10-m on-ice sprint performance than ST (P < .025).Conclusion:Combining plyometric and strength training for 8 wk was superior to strength training alone at improving 10-m on-ice sprint performance in high-level ice hockey players.
Aerobic Evaluation in Elite Slalom Kayakers Using a Tethered Canoe System: A New Proposal
Authors: Ferrari Homero Gustavo , Messias Leonardo H.D. , Reis Ivan G.M. , Gobatto Claudio A. , Sousa Filipe A.B. , Serra Camila C.S. , Manchado-Gobatto Fúlvia B. 
Published: December 2016

Background:Among other aspects, aerobic fitness is indispensable for performance in slalom canoe.Purpose:To propose the maximal-lactate steady-state (MLSS) and critical-force (CF) tests using a tethered canoe system as new strategies for aerobic evaluation in elite slalom kayakers. In addition, the relationship between the aerobic parameters from these tests and the kayakers’ performances was studied.Methods:Twelve male elite slalom kayakers from the Brazilian national team participated in this study. All tests were conducted using a tethered canoe system to obtain the force records. The CF test was applied on 4 d and analyzed by hyperbolic (CFhyper) and linear (CFlin) mathematical models. The MLSS intensity (MLSSint) was obtained by three 30-min continuous tests. The time of a simulated race was considered the performance index.Results:No difference (P < .05) between CFhyper (65.9 ± 1.6 N) and MLSSint (60.3 ± 2.5 N) was observed; however, CFlin (71.1 ± 1.7 N) was higher than MLSSint. An inverse and significant correlation was obtained between MLSSint and performance (r = –.67, P < .05).Conclusion:In summary, MLSS and CF tests on a tethered canoe system may be used for aerobic assessment of elite slalom kayakers. In addition, CFhyper may be used as an alternative low-cost and noninvasive method to estimate MLSSint, which is related with slalom kayakers’ performance.
Movement Patterns and Metabolic Responses During an International Rugby Sevens Tournament
Authors: Couderc Anthony , Thomas Claire , Lacome Mathieu , Piscione Julien , Robineau Julien , Delfour-Peyrethon Rémi , Borne Rachel , Hanon Christine 
Published: December 2016

Purpose:To investigate the running demands and associated metabolic perturbations during an official rugby sevens tournament.Methods:Twelve elite players participated in 7 matches wearing GPS units. Maximal sprinting speed (MSS) and maximal aerobic speed (MAS) were measured. High-intensity threshold was individualized relative to MAS (>100% of MAS), and very-high-intensity distance was reported relative to both MAS and MSS. Blood samples were taken at rest and after each match.Results:Comparison of prematch and postmatch samples revealed significant (P < .01) changes in pH (7.41–7.25), bicarbonate concentration ([HCO3–]) (24.8–13.6 mmol/L), and lactate concentration ([La]) (2.4–11.9 mmol/L). Mean relative total distance covered was 91 ± 13 m/min with ~17 m/min at high-intensity. Player status (whole-match or interchanged players), match time, and total distance covered had no significant impact on metabolic indices. Relative distance covered at high intensity was negatively correlated with pH and [HCO3–] (r = .44 and r = .42, respectively; P < .01) and positively correlated with [La] (r = .36; P < .01). Total distance covered and distance covered at very high intensity during the 1-min peak activity in the last 3 min of play were correlated with [La] (r = .39 and r = .39, respectively; P < .01).Conclusions:Significant alterations in blood-metabolite indices from prematch to postmatch sampling suggest that players were required to tolerate a substantial level of acidosis related to metabolite accumulation. In addition, the ability to produce energy via the glycolytic energy pathway seems to be a major determinant in match-related running performance.
A Comparison of Isometric Midthigh-Pull Strength, Vertical Jump, Sprint Speed, and Change-of-Direction Speed in Academy Netball Players
Authors: Thomas Christopher , Comfort Paul , Jones Paul A. , Dos’Santos Thomas 
Published: December 2016

Purpose:To investigate the relationships between maximal isometric strength, vertical jump (VJ), sprint speed, and change-of-direction speed (CoDS) in academy netball players and determine whether players who have high performance in isometric strength testing would demonstrate superior performance in VJ, sprint speed, and CoDS measures.Method:Twenty-six young female netball players (age 16.1 ± 1.2 y, height 173.9 ± 5.7 cm, body mass 66.0 ± 7.2 kg) from a regional netball academy performed isometric midthigh pull (IMTP), squat jumps (SJs), countermovement jumps (CMJs), 10-m sprints, and CoDS (505).Results:IMTP measures displayed moderate to strong correlations with sprint and CoDS performance (r = –.41 to –.66). The VJs, which included SJs and CMJs, demonstrated strong correlations with 10-m sprint times (r = –.60 to –.65; P < .01) and CoDS (r = –.60 to –.71; P = .01). Stronger players displayed significantly faster sprint (ES = 1.1–1.2) and CoDS times (ES = 1.2–1.7) and greater VJ height (ES = 0.9–1.0) than weaker players.Conclusion:The results of this study illustrate the importance of developing high levels of lower-body strength to enhance VJ, sprint, and CoDS performance in youth netball players, with stronger athletes demonstrating superior VJ, sprint, and CoDS performances.
Importance of Various Training-Load Measures in Injury Incidence of Professional Rugby League Athletes
Authors: Thornton Heidi R. , Delaney Jace A. , Duthie Grant M. , Dascombe Ben J. 
Published: December 2016

Purpose:To investigate the ability of various internal and external training-load (TL) monitoring measures to predict injury incidence among positional groups in professional rugby league athletes.Methods:TL and injury data were collected across 3 seasons (2013–2015) from 25 players competing in National Rugby League competition. Daily TL data were included in the analysis, including session rating of perceived exertion (sRPE-TL), total distance (TD), high-speed-running distance (>5 m/s), and high-metabolic-power distance (HPD; >20 W/kg). Rolling sums were calculated, nontraining days were removed, and athletes’ corresponding injury status was marked as “available” or “unavailable.” Linear (generalized estimating equations) and nonlinear (random forest; RF) statistical methods were adopted.Results:Injury risk factors varied according to positional group. For adjustables, the TL variables associated most highly with injury were 7-d TD and 7-d HPD, whereas for hit-up forwards they were sRPE-TL ratio and 14-d TD. For outside backs, 21- and 28-d sRPE-TL were identified, and for wide-running forwards, sRPE-TL ratio. The individual RF models showed that the importance of the TL variables in injury incidence varied between athletes.Conclusions:Differences in risk factors were recognized between positional groups and individual athletes, likely due to varied physiological capacities and physical demands. Furthermore, these results suggest that robust machine-learning techniques can appropriately monitor injury risk in professional team-sport athletes.
Within-Season Distribution of External Training and Racing Workload in Professional Male Road Cyclists
Authors: Metcalfe Alan J. , Menaspà Paolo , Villerius Vincent , Quod Marc , Peiffer Jeremiah J. , Govus Andrew D. , Abbiss Chris R 
Published: December 2016

Purpose:To describe the within-season external workloads of professional male road cyclists for optimal training prescription.Methods:Training and racing of 4 international competitive professional male cyclists (age 24 ± 2 y, body mass 77.6 ± 1.5 kg) were monitored for 12 mo before the world team-time-trial championships. Three within-season phases leading up to the team-time-trial world championships on September 20, 2015, were defined as phase 1 (Oct–Jan), phase 2 (Feb–May), and phase 3 (June–Sept). Distance and time were compared between training and racing days and over each of the various phases. Times spent in absolute (<100, 100–300, 400–500, >500 W) and relative (0–1.9, 2.0–4.9, 5.0–7.9, >8 W/kg) power zones were also compared for the whole season and between phases 1–3.Results:Total distance (3859 ± 959 vs 10911 ± 620 km) and time (240.5 ± 37.5 vs 337.5 ± 26 h) were lower (P < .01) in phase 1 than phase 2. Total distance decreased (P < .01) from phase 2 to phase 3 (10911 ± 620 vs 8411 ± 1399 km, respectively). Mean absolute (236 ± 12.1 vs 197 ± 3 W) and relative (3.1 ± 0 vs 2.5 ± 0 W/kg) power output were higher (P < .05) during racing than training, respectively.Conclusion:Volume and intensity differed between training and racing over each of 3 distinct within-season phases.
Countermovement-Jump-Phase Characteristics of Senior and Academy Rugby League Players
Authors: McMahon John J. , Murphy Shannon , Rej Sophie J.E. , Comfort Paul 
Published: December 2016

Purpose:Gross measures of countermovement-jump (CMJ) performance are commonly used to track maturational changes in neuromuscular function in rugby league (RL). The purpose of this study was to conduct both a gross and a more detailed temporal-phase analysis of the CMJ performances of senior and academy RL players, to provide greater insight into how neuromuscular function differs between these groups.Methods:Twenty senior and 14 academy (under-19) male RL players performed 3 maximal-effort CMJs on a force platform, with forward dynamics subsequently employed to allow gross performance measures and entire kinetic– and kinematic–time curves to be compared between groups.Results:Jump height (JH), reactive strength index modified, concentric displacement, and relative concentric impulse (C-IMP) were the only gross measures that were greater for senior players (d = 0.58–0.91) than for academy players. The relative force- and displacement–time curves were similar between groups, but the relative power– and velocity–time curves were greater (d = 0.59–0.97) for the senior players at 94–96% and 89–100% of the total movement time, respectively.Conclusions:The CMJ distinguished between senior and academy RL players, with seniors demonstrating greater JH through applying a larger C-IMP and thus achieving greater velocity throughout the majority of the concentric phase and at takeoff. Therefore, academy RL players should train to improve triple (ie, ankle, knee, and hip) extension velocity during the CMJ to bring their JH scores in line with those attained by senior players.
The Validity and Reliability of an iPhone App for Measuring Running Mechanics
Authors: Balsalobre-Fernández Carlos , Agopyan Hovannes , Morin Jean-Benoit 
Published: December 2016

The purpose of this investigation was to analyze the validity of an iPhone application (Runmatic) for measuring running mechanics. To do this, 96 steps from 12 different runs at speeds ranging from 2.77–5.55 m·s−1 were recorded simultaneously with Runmatic, as well as with an opto-electronic device installed on a motorized treadmill to measure the contact and aerial time of each step. Additionally, several running mechanics variables were calculated using the contact and aerial times measured, and previously validated equations. Several statistics were computed to test the validity and reliability of Runmatic in comparison with the opto-electronic device for the measurement of contact time, aerial time, vertical oscillation, leg stiffness, maximum relative force, and step frequency. The running mechanics values obtained with both the app and the opto-electronic device showed a high degree of correlation (r = .94–.99, p < .001). Moreover, there was very close agreement between instruments as revealed by the ICC (2,1) (ICC = 0.965–0.991). Finally, both Runmatic and the opto-electronic device showed almost identical reliability levels when measuring each set of 8 steps for every run recorded. In conclusion, Runmatic has been proven to be a highly reliable tool for measuring the running mechanics studied in this work.
The Associations Between Urbanicity and Physical Activity and Sitting Time in Mexico
Authors: Hermosillo-Gallardo Maria E. , Jago Russell , Sebire Simon J. 
Published: December 2016

Background:Approximately 17.4% of people in Mexico self-report physical activity levels below the World Health Organization’s guidelines and an average sedentary time of 16 hours per day.1 Low physical activity has been associated with noncommunicable disease risk factors and previous research suggests that urbanicity might be an important determinant of physical activity. The aim of this study was to measure urbanicity in Mexico and assess if it is associated with physical activity and sitting time.Methods:A sample of 2880 men and 4211 women aged 20 to 69 was taken from the 2012 Mexico National Health and Nutrition Survey and multivariable linear regression models were used to examine the association between physical activity, sitting time and urbanicity; adjusting for sex, education level, socioeconomic status and Body Mass Index. The urbanicity score and the 7 urbanicity subscores were estimated from the CENSUS 2010.Results:The subscores of demographic, economic activity, diversity and communication were negatively associated with physical activity. Sitting time was positively associated with the overall urbanicity, and the demographic and health subscores.Conclusions:There was evidence of associations between urbanicity and physical activity in Mexico.
Are Immigrants More Physically Active Than Native-Born Australians and Does it Changes Over Time? Evidence From a Nationally Representative Longitudinal Survey
Authors: Joshi Suresh , Jatrana Santosh , Paradies Yin 
Published: December 2016

Background:We investigated the differences and over time changes in recommended physical activity among foreign-born (FB) from English speaking countries (ESC) and non-English speaking countries (NESC) relative to native-born (NB) Australians, and whether the association between nativity and duration of residence (DoR) and physical activity is mediated by English language proficiency, socioeconomic status and social engagement/membership.Methods:This study applies multilevel group-meancentered mixed (hybrid) logistic regression models to 12 waves of longitudinal data (12,634 individuals) from the Household, Income and Labor Dynamics in Australia survey with engagement in physical activities for more than 3 times a week as the outcome variable.Results:Immigrants from ESC had higher odds of physical activity, while immigrants from NESC had significantly lower odds of physical activity than NB Australians, after adjusting for covariates. There was no evidence that these differences changed by DoR among immigrants from NESC, whereas ESC immigrants had higher odds of physical activity when their DoR was more than 20 years. We also found a mediating role of English language proficiency on immigrants physical activities.Conclusion:Appropriate health promotion interventions should be implemented to foster physical activities among NESC immigrants, considering English language proficiency as an important factor in designing interventions.
Psychosocial and Friend Influences on Objective Sedentary Behavior and Screen Time: A Mixed Methods Analysis
Authors: Garcia Jeanette M. , Agaronov Alen , Sirard John R. , Whaley Diane , Rice David J. , Weltman Arthur 
Published: December 2016

Background:Sedentary behavior (SB) increases throughout adolescence, and is associated with adverse health outcomes.Purpose:Examine psychosocial and friend influences on SB and screen time in adolescents using a mixed-methods design.Methods:108 middle and high school students wore accelerometers to measure objective SB, completed screen time and psychosocial questionnaires, and nominated friends to complete activity questionnaires. Focus groups centered around influences on SB behavior. Regression analyses and NVivo software analyzed quantitative and qualitative data.Results:Screen time was associated with greater screen time enjoyment, lower self-efficacy, and friends’ screen time (r2 = .21, P < .0001). Friends influenced whether adolescents engaged in screen time behaviors, with active friends encouraging less screen time.Conclusion:Active friends influenced adolescents to engage in less SB. Interventions should place an emphasis on encouraging less screen time, and providing opportunities for adolescents and their friends to engage in activities that promote physical activity rather than SB.
Patterns and Predictors of Change in Moderate-to-Vigorous Physical Activity Over Time in Multiple Sclerosis
Authors: Klaren Rachel E. , Sasaki Jeffer E. , McAuley Edward , Motl Robert W. 
Published: December 2016

Background:Physical inactivity is common in persons with multiple sclerosis (MS), but there is very little known about the pattern and predictors of changes in physical activity over time.Purpose:This study examined changes in moderate-to-vigorous physical activity (MVPA) over a 30-month time period and the demographic and clinical predictors of such changes in relapsing-remitting MS (RRMS).Methods:269 persons with MS wore an accelerometer for a 7-day period and completed a demographic/clinical scale every 6 months over a 30-month period. Data were analyzed using latent class growth modeling (LCGM).Results:LCGM identified a two-class model for changes in levels of MVPA over time. Class 1 involved higher initial levels of MVPA and linear decreases in MVPA over time, whereas Class 2 involved lower initial levels of MVPA and linear increases in MVPA over time. LCGM further indicated that males were more likely (OR = 5.8, P < .05) and those with higher disability status were less likely (OR = 0.51, P < .05) to belong to Class 1 than Class 2.Conclusion:Levels of MVPA change over time in persons with RRMS and the pattern of change suggests that behavioral physical activity interventions for persons with MS might target men and those with lower disability.
Oncogenic MET as an Effective Therapeutic Target in Non–Small Cell Lung Cancer Resistant to EGFR Inhibitors: The Rise of the Phoenix
Authors: Trusolino Livio 
Published: December 2016

Abstract
Summary: Anecdotal reports have shown that concomitant inhibition of EGFR and MET can be clinically effective in patients with non–small cell lung cancer carrying EGFR mutations and MET amplification, but large phase III trials in genetically unselected individuals have failed to confirm the benefit of this combination therapy. A new study corroborates the evidence that lung cancer susceptibility to EGFR and MET blockade is sustained by genetically based activation of both targets and identifies a mutation in MET that confers acquired resistance to standard MET inhibitors hitting the active kinase, yet is vulnerable to other MET-directed compounds with a different binding mode. Cancer Discov; 6(12); 1306–8. ©2016 AACR.
See related article by Bahcall and colleagues, p. 1334.
Culprit or Bystander? The Role of the Fallopian Tube in “Ovarian” High-Grade Serous Carcinoma
Authors: Swisher Elizabeth M. , Garcia Rochelle L. , Kilgore Mark R. , Norquist Barbara M. 
Published: December 2016

Abstract
Summary: The concurrence of intraepithelial high-grade neoplasia in the fallopian tube with metastatic implants has been taken as evidence of a tubal origin for high-grade serous pelvic carcinomas. In the current issue, Eckert and colleagues perform detailed genomic phylogenetic analyses and demonstrate that some cases of high-grade serous intraepithelial tubal neoplasia are metastatic implants and not precursor lesions. Cancer Discov; 6(12); 1309–11. ©2016 AACR.
See related article by Eckert and colleagues, p. 1342.