bluuebunny/crossref_metadata_2025_split huggingface dataset:
Very Extended Ionized Gas Discovered around NGC 1068 with the Circumgalactic Hα Spectrograph
Authors: Melso Nicole , Schiminovich David , Sitaram Meghna , Cevallos-Aleman Ignacio , Cruvinel Santiago Bárbara , Smiley Brian , Ong Hwei Ru 
Published: October 2024

Abstract
We have performed wide-field, ultra-low-surface-brightness Hα emission-line mapping around NGC 1068 with the newly commissioned Circumgalactic Hα Spectrograph. NGC 1068 is notable for its active galactic nucleus, which globally ionizes gas in the disk and halo. Line-emitting diffuse ionized gas is distributed throughout the galactic disk and large-scale ionized filaments are found well beyond the disk, aligned with the cone angle of the central jet. We report the discovery of a new ribbon of ionized gas around NGC 1068 beyond even the known outer filamentary structure, located 20 kpc from the galaxy. The Hα surface brightness of this ribbon is on the order of the bright telluric lines, ranging from 4 to 16 R, with fainter regions on the order of the sky background continuum. Unlike previous extended emission, the ribbon is not as well aligned with the current axis of the central jet. It is not associated with any galactic structure or known tidal features in the halo of NGC 1068, though it may originate from a larger distribution of unmapped neutral atomic or molecular gas in the halo. The morphology of the ribbon emission in Hα is correlated with extended UV emission around NGC 1068. Hα-to-UV flux ratios in the ribbon are comparable to extended emission-line ratios in the halos of NGC 5128, NGC 253, and M82. The Hα excess in the ribbon gas suggests ionization by slow shocks or a mixture of in situ star formation and photoionization and collisional ionization processes.
IC 10 X-1: A Double Black Hole Progenitor Probably Formed through Stable Mass Transfer
Authors: Wang Gui-Yu , Shao Yong , He Jian-Guo , Xu Xiao-Jie , Li Xiang-Dong 
Published: October 2024

Abstract
IC 10 X-1 is one of the close X-ray binaries containing a Wolf–Rayet donor, which can provide an evolutionary link between high-mass X-ray binaries and gravitational wave sources. It is still unclear about the precise nature of the accreting compact object in IC 10 X-1, although it looks more like a black hole (BH) than a neutron star. In this work, we use a binary population synthesis method to simulate the formation of IC 10 X-1–like binaries by assuming different common-envelope ejection efficiencies. This work represents a big step forward over previous studies since we adopt new criteria for mass-transfer stability. These criteria allow the formation of IC 10 X-1–like systems without experiencing common envelope evolution. Based on our calculations, we propose that the compact object in IC 10 X-1 is a BH with a mass of ∼10–30 M
⊙ and the progenitor evolution of this binary probably just experienced stable mass transfer.
Temporally Resolved Type III Solar Radio Bursts in the Frequency Range 3–13 MHz
Authors: Vecchio Antonio , Maksimovic Milan , Chrysaphi Nicolina , Kontar Eduard P. , Krupar Vratislav 
Published: October 2024

Abstract
Radio observations from space allow to characterize solar radio bursts below the ionospheric cutoff, which are otherwise inaccessible, but suffer from low, insufficient temporal resolution. In this Letter we present novel, high-temporal resolution observations of type III solar radio bursts in the range 3–13 MHz. A dedicated configuration of the Radio and Plasma Waves (RPW) High Frequency Receiver (HFR) on the Solar Orbiter mission, allowing for a temporal resolution as high as ∼0.07 s (up to 2 orders of magnitude better than any other spacecraft measurements), provides for the very first time resolved measurements of the typical decay time values in this frequency range. The comparison of data with different time resolutions and acquired at different radial distances indicates that discrepancies with decay time values provided in previous studies are only due to the insufficient time resolution not allowing to accurately characterize decay times in this frequency range. The statistical analysis on a large sample of ∼500 type III radio bursts shows a power low decay time trend with a spectral index of −0.75 ± 0.03 when the median values for each frequency are considered. When these results are combined with previous observations, referring to frequencies outside the considered range, a spectral index of −1.00 ± 0.01 is found in the range ∼0.05–300 MHz, compatible with the presence of radio-wave scattering between 1 and 100 R
☉.
Near-infrared Spectral Homogeneity of the Didymos System Before and After the DART Impact*
Authors: Ieva Simone , Mazzotta Epifani E. , Dotto E. , Petropoulou V. , Deshapriya J. D. P. , Hasselmann P. H. , Poggiali G. , Perna D. , Dall’Ora M. , Lucchetti A. , Pajola M. , Ivanovski S. L. , Rossi A. , Brucato J. R. , Palumbo P. , Della Corte V. , Zinzi A. , Thomas C. A. , de León J. , Kareta T. , Moskovitz N. , Chabot N. L. , Rivkin A. S. , Amoroso M. , Bertini I. , Capannolo A. , Caporali S. , Ceresoli M. , Cremonese G. , Gai I. , Gomez-Casajus L. , Gramigna E. , Impresario G. , Lasagni Manghi R. , Lavagna M. , Lombardo M. , Modenini D. , Pirrotta S. , Tortora P. , Tusberti F. , Zannoni M. , Zanotti G. 
Published: October 2024

Abstract
We spectroscopically characterized the Didymos system, target of the Double Asteroid Redirection Test (DART)/Light Italian Cubesat for Imaging of Asteroids (LICIACube) space mission, close in time to the DART impact event, during six nights between 2022 August and November at Telescopio Nazionale Galileo. Here, we show that near-infrared (NIR) spectra (0.75–2.25 μm) look mostly similar within the same night and between different nights. They are in good agreement with the only spectrum previously available in the literature, observed almost 20 years before those reported in this paper. During one of the observing nights we also obtain spectroscopy information on the ejecta tail induced by the DART impact. The spectrum of the ejecta tail is also very similar to Didymos/Dimorphos itself. All of these aspects seem to suggest that the Didymos system in the NIR looks mostly homogeneous, with very subtle spectral variations.
Hot Versus Cold Debriefing in a Nursing Context: An Integrative Review
Authors: Alanezi Fahad Zeed , Miller Elaine , Morrison Caroline F. , Kelcey Benjamin , Wagner Robin 
Published: October 2024

This article has been amended to include factual corrections. An error was identified subsequent to its original publication. This error was acknowledged on page 730, volume 63, issue 11. The online article and its erratum are considered the version of record.

Background
Hot debriefing occurs shortly after simulations or real-life events, whereas cold debriefings occur after 24 hours. This integrative review examined the effects of hot versus cold debriefing after simulation on prelicensure students.

Method
Whittemore and Knafl's five-stage method was followed. Databases searched included PubMed, CINAHL, Scopus, and PsycINFO. The inclusion criteria were studies published in English that involved prelicensure nursing students and measured the effect of hot or cold debriefing.

Results
Themes emerged from 10 studies and included clinical judgment and decision making, knowledge and skills, participant experiences, reflection, and psychological safety and self-efficacy.

Conclusion

Hot debriefing was preferred by participants, but cold debriefing resulted in higher knowledge and skills scores. In addition, students in the cold debriefing group were more conformable and in a safe environment compared with the hot debriefing group. Drawing a strong conclusion was difficult due to heterogeneity in study designs and methods.

[
J Nurs Educ
. 2024;63(10):653–658.]
Fth1-mScarlet Reports Monocyte State during Lipopolysaccharide-induced Lung Inflammation
Authors: Michalides Brandon A , Shoger Karsen E , Kruszelnicki Sonia , Cheemalavagu Neha , Martinez-Turak Anamarie , Jackson-Strong Morgan , Laughlin Colin R , Betsur Omkar S , Colby Devon , Meisel Marlies , Gingras Sebastien , Gottschalk Rachel A 
Published: October 2024

Abstract
Monocytes and macrophages are central to host defense but also contribute to inflammation-associated pathology. Efforts to manipulate monocyte and macrophage function are limited by our ability to effectively quantify the functional programs of these cells. We identified the gene Fth1, which encodes the ferritin H chain, as highly predictive of alveolar macrophage transcriptomic states during LPS-induced lung inflammation and developed an Fth1-mScarlet reporter mouse. In the steady-state lung, high Fth1-mScarlet expression is restricted to alveolar macrophages. In response to LPS-induced lung inflammation, Fth1 reporter activity is robustly increased in monocytes, with its expression reporting genes that are differentially expressed in monocytes versus macrophages. Consistent with this reporter-associated gene profile, within the Lyz2-GFP+CD11b+Ly6C+ gate, the highest Fth1 reporter expression was observed in CD11c+ cells, indicative of monocyte-to-macrophage differentiation. Although Fth1-mScarlet was induced in monocytes responding to either TLR4 ligation or M-CSF–induced macrophage differentiation in vitro, TLR4-dependent expression occurred with greater speed and magnitude. Considering this, we suggest that Fth1-mScarlet expression reports monocyte-to-macrophage differentiation, with increased expression in proinflammatory states. Dissecting macrophage differentiation from inflammatory programs will be enhanced when combining Fth1-mScarlet with other reporter systems. Thus, the Fth1-mScarlet model addresses an important lack of tools to report the diverse spectrum of monocyte and macrophage states in vivo.
NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children
Authors: Dick Jenna K , Sangala Jules A , Krishna Venkatramana D , Khaimraj Aaron , Hamel Lydia , Erickson Spencer M , Hicks Dustin , Soigner Yvette , Covill Laura E , Johnson Alexander K , Ehrhardt Michael J , Ernste Keenan , Brodin Petter , Koup Richard A , Khaitan Alka , Baehr Carly , Thielen Beth K , Henzler Christine M , Skipper Caleb , Miller Jeffrey S , Bryceson Yenan T , Wu Jianming , John Chandy C , Panoskaltsis-Mortari Angela , Orioles Alberto , Steiner Marie E , Cheeran Maxim C J , Pravetoni Marco , Hart Geoffrey T 
Published: October 2024

Abstract
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication of SARS-CoV-2 infection characterized by multiorgan involvement and inflammation. Testing of cellular function ex vivo to understand the aberrant immune response in MIS-C is limited. Despite strong Ab production in MIS-C, SARS-CoV-2 nucleic acid testing can remain positive for 4–6 wk postinfection. Therefore, we hypothesized that dysfunctional cell-mediated Ab responses downstream of Ab production may be responsible for delayed clearance of viral products in MIS-C. In MIS-C, monocytes were hyperfunctional for phagocytosis and cytokine production, whereas NK cells were hypofunctional for both killing and cytokine production. The decreased NK cell cytotoxicity correlated with an NK exhaustion marker signature and systemic IL-6 levels. Potentially providing a therapeutic option, cellular engagers of CD16 and SARS-CoV-2 proteins were found to rescue NK cell function in vitro. Taken together, our results reveal dysregulation in Ab-mediated cellular responses of myeloid and NK cells that likely contribute to the immune pathology of this disease.
Research advances in inflammation and oxidative stress in varicocele-induced male infertility: a narrative review
Authors: Wang Li-Hong , Zheng Lei , Jiang Hui , Jiang Tao 
Published: October 2024

Abstract
Varicocele, the most common and treatable cause of male infertility, significantly impacts fertility. The pathophysiological mechanisms of varicocele have not been fully understood yet. Recent studies have focused on the pathophysiology of varicocele-induced infertility, highlighting inflammation and oxidative stress as key contributing factors. We reviewed recent research on the roles of inflammation and oxidative stress in the pathophysiology of varicocele and found that they negatively impact semen parameters, spermatogenesis, and testicular and epididymal function. In addition, this article summarizes the related factors of inflammation and oxidative stress caused by varicocele. Finally, a brief consideration on the treatments to address inflammation and oxidative stress is proposed. This review may provide treatment options and targets for varicocele-induced infertility. However, the relationship between inflammation and oxidative stress in varicocele still needs further study.
Comparing the effect of letrozole on the growth of boys aged 12–16 years with constitutional short stature: A clinical randomized trial study
Authors: Homaei Ali , Razzaghi Alireza , Shamsi Maryam , Safari Zahra , Saffari Fatemeh 
Published: October 2024

Objectives
This study aimed to compare the effect of letrozole on the height of boys aged 12–16 years with constitutional short stature after the onset of the third stage of puberty.

Methods
This clinical randomized trial study was performed on 93 boys with constitutional short stature referring to the Pediatric Endocrine Clinic in Qazvin, Iran. The measurements of patient height and predicted adult height (PAH) were assessed after 1 and 2 years. The patients were treated using letrozole (2.5 mg/day) or placebo (control).

Results
The level of letrozole increased the PAH compared to control. The predicted height in patients with constitutional short stature increased significantly by 5.52 cm, only 1 year after the administration of letrozole, compared to the placebo group (P = 0.03). However, after receiving letrozole in the second year, the predicted height in boys with constitutional short stature increased by 2.34 cm (P > 0.05) compared to the first year. In boys with constitutional short stature, the predicted height increased by 7.86 cm after 2 years in the intervention group receiving letrozole and 3.1 cm in the control group (P > 0.05). Furthermore, no significant difference was observed between the groups receiving letrozole and placebo before and after the intervention in terms of laboratory findings, such as hemoglobin level and serum cholesterol level (P > 0.05).

Conclusions
The results showed that the administration of letrozole at the third stage of puberty in boys aged 6–12 with constitutional short stature caused a statistically significant increase in the mean of PAH compared to placebo.
Early Prediction of Native Arteriovenous Fistula for Maturation by Doppler Ultrasound Study
Authors: Gupta Shivali , Saha Sudipta , Singh Katyayni , Andley Manoj , Anand Rama , Satija Bhawna , Pathania O. P. 
Published: October 2024

Introduction:
There are significant chances of maturation failure in arteriovenous fistulas (AVFs) made for vascular access for hemodialysis. AVFs are usually assessed for maturation 6 weeks after the operation. Significant time is lost for performing a salvage radiological procedure or making an alternative AVF, in case the AVF fails to mature.

Materials and Methods:
This prospective observational study was conducted to predict the chances of maturation of AVF by Doppler ultrasound (USG) study. One hundred and thirty-seven patients in whom native AVF was made as a vascular access procedure for hemodialysis were included in the study. In five patients, palpable thrill was absent after 48 h of operation and were excluded from the study. The velocity of the blood, diameter of the vessel, and depth of the vessel from the skin were assessed by USG Doppler 3 weeks after the operation and were correlated with AVF maturation.

Results:
Successful maturation occurred in 114 (86.3%) AVF. The flow rate of the blood and depth of the vein were statistically different in successful and unsuccessful AVF maturation for both the groups of radial artery (RA) and brachial artery (BA) based AVF. For RA AVF, successful maturation was predicted by the flow rate of 539 mL/min (sensitivity 95% and specificity 83%) and 4.2 mm diameter of the vein (sensitivity 93% and specificity 100%). For BA AVF, successful maturation was predicted by the flow rate of 456 mL/min (sensitivity 93% and specificity 100%) and 5.7 mm diameter of the vein (sensitivity 77% and specificity 100%). The measurement of flow and depth at 3 weeks after AVF may predict the maturation of AVF.

Conclusion:
It will be beneficial to do a USG Doppler study 3 weeks after making AVF, as the measurement of flow may predict the maturation of AVF.
Role of Vasakantakadi Lehyam and Phala Ghrutam in the Management of Asthenozoospermia: A Case Study
Authors: Lakshmi Mutnuri Vasantha 
Published: October 2024

Abstract
Infertility leading to the inability to conceive is a common problem but indication of assisted reproductive technologies (ARTs) is not a mandate always. Female factors are major highlighted issues in these cases but the importance of male factors and/or some unexplained reasons are not often explored. Ayurveda is known for treatments of infertility that range in variety, and cater based on the specific needs of each case. These treatment options often are the choice of many couples who wish to conceive naturally avoiding ART. We report a case study of a couple who presented with primary infertility treated with Ayurveda treatments with primary improvements in the male component (asthenozoospermia) and addressing a secondary/subclinical infection in his female counterpart.
Ayurvedic Approach to Visarpa (Herpes Zoster): A Case Report
Authors: Timande Sanket Anilrao , Rathod Sanjivani Nitin 
Published: October 2024

Abstract

Visarpa is a clinical syndrome characterized by vitiation of Vata, pitta, and predominant Tridosha. A 47-year-old female patient, suffering from Visarpa (herpes zoster), was treated with Ayurvedic medicine in the IPD, Arogyashala Rugnalaya, Nashik, from September 27, 2023 to October 14, 2023. Jalaukavacharaṇa (Hirudotherapy), Virechana Karma (therapeutic purgation), and Shamana Chikitsa (Ayurvedic medicinal treatment) were administered. The intensity of pain was recorded on a pictorial Visual Analog Scale, also assessed as per the zoster brief pain inventory (ZBPI) questionnaire, and improvement was seen in pain reduction. Herpes zoster pain management with Ayurvedic medicine offers a novel, simple, superior, and affordable treatment. Hence, this study was carried out to prove that Ayurvedic management yields remarkable results in Visarpa (herpes zoster). However, large-scale randomized controlled trials are required to further validate the same.
Embracing Radiant Living: A Holistic Expedition Through Ayurvedic Psychotherapy, Yogic Practices, and Herbal Therapies in Major Depressive Disorder
Authors: Chauhan Kunjal Chetanbhai , Shirkande Abhijeet Sarjerao 
Published: October 2024

Abstract
The article highlights the high prevalence of major depressive disorder (MDD) in India, with 57 million individuals suffering from it (15.1% prevalence). It advocates for holistic techniques like yoga, herbal therapy, and Ayurvedic psychotherapy for long-term mental health recovery. The patient exhibits symptoms of panic disorder, hypothyroidism, obesity, and early-onset arterial hypertension in addition to MDD (Vishad). An Ayurvedic examination indicates a vata kapha prakriti, decreased digestive capacity, and a range of physical complaints, which correlates with the HAM-D scale results. This case study demonstrates the synergy between conventional and holistic methods and offers proof of their efficacy. Regular pranayama and yogasana practice improve perception and highlight the need for integrative approaches to Vishad (depression) treatment. It also emphasizes how important holistic methods were to her amazing recovery. The MDD patient witnessed substantial improvement through a holistic approach, combining Ayurvedic treatments with the regular practice of yogasana and pranayama, highlighting the comprehensive benefits of this integrated therapeutic strategy for mental health.
Evaluation of safety and efficacy of Vamana Karma in healthy and diseased individuals: a systemic review
Authors: Kumari Kavita , Bhatted Santosh Kumar 
Published: October 2024

Abstract

Introduction:
One of the five Pradhana Karmas (five chief procedures) of Panchakarma is Vamana Karma (therapeutic emesis), which is essentially a Samshodhana Karma (purification technique). Ayurvedic literature states that after Samyaka Vamana (proper Vamana), a person perceives Hrit (precordium), Kantha (voice/throat), and Shirah (head) as feelings of lightness. In the Ayurvedic system, this process is beneficial for both healthy and sick individuals in terms of bodily cleansing and dosha extraction, particularly for Kapha. In contrast, this procedure is very rarely conducted due to its associated reluctance as it is comparatively a complicated procedure with other Panchakarma therapies.

Aims and Objective:
The objective of this research is to examine numerous papers written by different writers on Vamana Karma and to establish a conceptual framework that supports the notion that Vamana Karma is safe and helpful for both healthy and unwell persons.

Research Methodology:
This study was done following the standards outlined in the Cochrane Handbook of Systematic Study of Interventions. The findings are described in adherence to the Preferred Reporting Guideline for Systematic Reviews. The search included electronic databases from 1946 to the present, the Database of Systematic Reviews from 2005 to January 2015, and PubMed also recorded the searches. The search engine Google was used to get further online resources and data. This article reviews eight different research articles on Vamana in healthy and diseased individuals by different authors, these articles were assessed for the formulated question, identify study relevance appraise tier quality, and summarize the evidence to rule out the safety and efficacy of Vamana Karma.

Results:
It was observed in all the studies that Vamana is an effective technique to alleviate diseases and is safe to execute if the incorporated methodology is correct, in all the cases there were no complications found when undertaken methodically with maximum efficacy.

Conclusion:
This study concludes that Vamana is a safe and effective Panchakarma procedure.
Enhanced view totally extraperitoneal approach: The best available option for recurrent incisional hernias following previous laparoscopic intraperitoneal onlay mesh plus repairs
Authors: Shenoy K. Ganesh 
Published: October 2024

Abstract
The available options for recurrent incisional hernias (RIH) following previous laparoscopic intraperitoneal onlay mesh (IPOM) plus were open onlay repair, open Rives–Stoppa (RS), laparoscopic enhanced view totally extraperitoneal-RS (ETEP-RS) and laparoscopic subcutaneous onlay mesh repair. Majority of these RIH were managed by open onlay mesh repairs or laparoscopic Redo IPOM plus. There are not much data available in the literature on the ETEP approach for RIH following previous IPOM plus with the placement of mesh in the retrorectus space. In this article, I would like to share technical aspects, challenges faced and tips to overcome these challenges of performing ETEP for RIH following previous IPOM plus repairs.
Endoclose-assisted intracorporeal intestinal anastomosis
Authors: Mouawad Christian , Ghedira Abdessalem , Dager Nehad 
Published: October 2024

Abstract
While performing an intracorporeal intestinal anastomosis in minimally invasive procedures, surgeons may be encountered with many limitations which made many of them go back to doing extracorporeal anastomosis. In this article, we describe a simple but efficient technique using the Endoclose which improves the surgeon’s ability to enhance the anastomosis’ exposure while suturing, without having to add extra trocars.