bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Improved Procedures for the Syntheses of Pyrido‐ and Pyrrolo(2,3‐d)pyrimidines, and Ribosides Thereof.
Authors: ITOH T. , MELIK‐OGANDZHANYAN R. G. , ISHIKAWA I. , KAWAHARA N. , MIZUNO Y. , HONMA Y. , HOZUMI M. , OGURA H. 
Published: May 2016

AbstractThe chloropyrimidine (I) is coupled with the allylamines (II) to give the corresponding substitution products (III).
ChemInform Abstract: Polyazapolycyclics by Condensation of Aldehydes with Amines. Part 2. Formation of 2,4,6,8,10,12‐Hexabenzyl‐2,4,6,8,10,12‐hexaazatetracyclo‐(5.5.0.05,9.03,11)dodecanes from Glyoxal and Benzylamines.
Authors: NIELSEN A. T. , NISSAN R. A. , VANDERAH D. J. , COON C. L. , GILARDI R. D. , GEORGE C. F. JUN. , FLIPPEN‐ANDERSON J. L. 
Published: May 2016

AbstractCyclocondensation reaction of the benzylic amines (I) with glyoxal (II) in the presence of formic acid is performed in aqueous acetonitrile or methanol to produce the hexaazaisowurtzitanes (V).
ChemInform Abstract: Synthesis, Characterization, Dipole Moment and Properties of Bishomooxacalix(4)arenes.
Authors: PERRIN R. , BOURAKHOUADAR M. , DUCHAMP C. 
Published: May 2016

AbstractThe reaction of the phenols (I) with the aldehyde (II) leads to the title compounds (III) and calix(8)arenes.
ChemInform Abstract: Chemistry of 1,8‐Substituted Naphthalenes. Part 20. New Derivatives of Naphtho(1,8‐bc)oxepin.
Authors: TKACHENKO V. V. , TREGUB N. G. , KNYAZEV A. P. , MEZHERITSKII V. V. 
Published: May 2016

AbstractIn the presence of a base the reaction between equimolar quantities of the aldehydes (I) and malonodinitrile (II) affords the dinitriles (III), whereas the unsubstituted aldehyde (V) reacts with two molecules of the dinitrile (II) to yield the heterocyclic derivative (VI) irrespective of the molar ratio of the reactants.
ChemInform Abstract: Synthesis and Reactions of Tricyclotetradecane and Bicyclododecane Derivatives.
Authors: BUCHBAUER G. , ROBIEN W. , SOVA A. , SENGER J. , AMESBERGER B. , GERSTMAYR G. 
Published: May 2016

AbstractOxatricyclo(7.3.2.02,7)tetradecane derivatives, e.g. (III) or (V), and bicyclo(6.4.0)dodecane derivatives, e.g. (VIII), (IX), or (XI), are synthesized as analogues to "hetero‐cage‐compounds", the antiviral and fungicidal activity of which is known.
ChemInform Abstract: Cyclic Phenyl Carbamates of the Miotin Type and Their Action on Acetylcholinesterase.
Authors: AMSTUTZ R. , ENZ A. , MARZI M. , BOELSTERLI J. , WALKINSHAW M. 
Published: May 2016

AbstractSeveral six‐, seven‐ and eight‐membered cyclic carbamates such as (VII) or (VIII) are prepared as analogues of miotin (X) and physostigmine (XI).
ChemInform Abstract: Tautomerism and Isomerism of α‐Amino Carbonyl Compounds. Regioselectivity in the Phosphorylation of Secondary α‐Amino Ketones.
Authors: BALITSKII YU. V. , PIPKO S. E. , KOLODKA T. V. , POVOLOTSKII M. I. , SINITSA A. D. 
Published: May 2016

AbstractThe α‐amino ketone (I) is coupled with the phosphinous amide (II) or the phosphinic amide (IV) to give the phosphinoxy (III) and the phosphinoyloxy imine (V) respectively.
ChemInform Abstract: Synthesis of Acyloxyalkyl Acylphosphonates as Potential Prodrugs of the Antiviral Trisodium Phosphonoformate (Foscarnet Sodium).
Authors: IYER R. P. , PHILLIPS L. R. , BIDDLE J. A. , THAKKER D. R. , EGAN W. , AOKI S. , MITSUYA H. 
Published: May 2016

AbstractPhosphorous acid (I) forms the tris(trimethylsilyl)phosphite (III) which is substituted with the chloroformates (IV) to give the phosphonates (V).
ChemInform Abstract: Substituted Ammonium Salts of Trichloromethylphosphonic Acid Alkyl Esters and Alkyl(Aryl)trichloromethylphosphinic Acids.
Authors: KHARRASOVA F. M. , RUZAL' G. I. , KOVALENKO YU. P. , KEL'BEDINA Z. A. 
Published: May 2016

AbstractThe phosphinates (I) are coupled with the amines (II) to give the ammonium salts (III).
ChemInform Abstract: Syntheses and X‐Ray Crystal Structures of the Compounds (ArPAs)2 and (ArPSb)2 (Ar: 2,4,6‐(tBu)3C6H2). P2As2‐ and P2Sb2‐Substituted Analogues of Bicyclo(1.1.0)butane.
Authors: JUTZI P. , MEYER U. , OPIELA S. , OLMSTEAD M. M. , POWER P. P. 
Published: May 2016

AbstractThe two novel bicyclic derivatives (II) (space group P21/n, Z = 8) and (VI) (P1, Z=2) represent the first well‐characterized example of their type.
ChemInform Abstract: Unusual Bromination of Ethyl Derivatives of Trivalent Arsenic.
Authors: KOKOREV G. I. , MUSIN R. Z. , YAMBUSHEV F. D. 
Published: May 2016

AbstractBromination of the ethylarsines (Ib) ‐ (Ig) proceeds under release of the ethyl group and formation of the bromoarsines (II).
ChemInform Abstract: Synthesis of Vanadium, Niobium, and Tantalum Silylimido Complexes and Reactivity of Their Nitrogen‐Silicon Bonds.
Authors: JONES C. M. , LERCHEN M. E. , CHURCH C. J. , SCHOMBER B. M. , DOHERTY N. M. 
Published: May 2016

AbstractThe dimeric chloro‐bridged silylimido complexes (III) are obtained as shown.
ChemInform Abstract: A Novel Route to 1,3‐Diphospholide Ions. Synthesis and X‐Ray Structure Analysis of a 1,3‐Diphosphaferrocene.
Authors: MAIGROT N. , RICARD L. , CHARRIER C. , MATHEY F. 
Published: May 2016

AbstractStarting with the 1,2‐diphosphete (I) the isomers (IV) are obtained with (IVa) as the main product.
ChemInform Abstract: Insertion of a Copper Nitrene into a C‐H Bond to Form Bis(2‐(phenylamino)‐1,10‐phenanthrolinato)dicopper(I): A Short Cu‐Cu Distance with No Bond?
Authors: LEE S. W. , TROGLER W. C. 
Published: May 2016

AbstractThe complex (I) reacts with the dianion of (II) to yield the Cu(I) dimer (III) (space group P21/n; Z=2) by insertion of N‐Ph into the ortho C‐H bond of phenanthroline.
ChemInform Abstract: Synthesis and Characterization of Novel (Cyclopentadienyl)nitroruthenium Complexes.
Authors: SZCZEPURA L. F. , TAKEUCHI K. J. 
Published: May 2016

AbstractThe reaction of RuCl3 with freshly cracked dicyclopentadiene and triphenylphosphine forms the complex (I), which serves as starting material for the synthesis of the nitro derivatives (V) and (VIII).
ChemInform Abstract: Five‐Coordinate Platinum(II) Hydrides Containing 1,1,4,7,10,10‐Hexaphenyl‐1,4,7,10‐tetraphosphadecane as a Tetradentate Monometallic Ligand.
Authors: BRUEGGELLER P. + 
Published: May 2016

AbstractThe title complexes (I) are prepared by NaBH4 reduction of the corresponding Pt(II) chlorides ((Pt(Cl)L)X giving (Ia) and (Ic)) and tetracoordinate Pt(II) complexes ((PtL)(BPh4)2 giving (Ib)) in 75‐90% yield.
ChemInform Abstract: Synthesis of Optically Pure Grasshopper Ketones and of Its Diastereoisomers and Related Compounds.
Authors: BAUMELER A. , BRADE W. , HAAG A. , EUGSTER C. H. 
Published: May 2016

AbstractStarting with the known aldehyde (I) the synthesis of four enantiomerically pure grasshopper ketones such as (IX) and of their oxo derivatives is described.
ChemInform Abstract: Diterpene Imines. Preparation of 2‐Azalauren‐1‐ene and the Facile Autoxidation of 6‐Azadihydrorimuene.
Authors: HAYMAN A. R. , HANTON L. R. , WEAVERS R. T. 
Published: May 2016

AbstractThe azalaurenene (II) is obtained by treatment of the amide (Ia) with iodosylbenzene and formic acid.
ChemInform Abstract: Reactions of Steroidal Nitroolefins with Ethanethiol and BF3‐Etherate Catalyst.
Authors: SHAFIULLAH SHAFIULLAH , SINGH R. K. , ANSARI S. A. 
Published: May 2016

AbstractIn the presence of BF3·Et2O, 6‐nitrocholest‐5‐ene (Ia), its 3β‐acetoxy derivative (Ib) and its 3β‐chloro derivative (Ic) undergo smooth reaction with EtSH (II) to afford the corresponding 5α‐ethylthio‐6‐ketoximes (III).
ChemInform Abstract: Synthesis and Pharmacological Activity of Substituted Nicotinoylamino Acids.
Authors: KUZNETSOVA E. A. , VORONINA T. A. , KHROMOVA I. V. , GARIBOVA T. L. , TOSINA E. K. , STOLYAROVA L. G. , TROITSKAYA V. S. , SMIRNOV L. D. 
Published: May 2016

AbstractReaction of the nicotinic azides (I) with the amino acids (II) gives the N‐nicotinoylamino acids (III).
ChemInform Abstract: Synthesis of the Stereoisomers of 1‐O‐(2′‐Methoxyhexadecyl)glycerol and Some Phosphocholine Derivatives.
Authors: STAELLBERG G. A. M. + 
Published: May 2016

AbstractAll four stereoisomers (VIIa), (VIIb), (VIIIa) and (VIIIb) of 1‐O‐(2‐methoxyhexadecyl)glycerol are synthesized.
ChemInform Abstract: Approaches to the Synthesis of 5‐Benzylidene‐2‐imidazolin‐4‐ones.
Authors: PRAGER R. H. , TSOPELAS C. 
Published: May 2016

AbstractTo complete the synthesis of the natural compound (IV), the ketone (I) is condensed with glycocyamidine with the aim to form the desired imidazolinone (III), but the product (II) is obtained by this reaction.
ChemInform Abstract: Synthesis of 5‐(Alkylamino)‐1‐β‐D‐ribofuranosyl‐1H‐imidazole‐4‐carboxamides, Key Intermediates for the Synthesis of 3‐Alkyl‐9‐β‐D‐ribofuranosylpurine Derivatives.
Authors: ITAYA T. , SAITO T. , HARADA T. , KAGATANI S. , FUJII T. 
Published: May 2016

AbstractThe benzyloxyadenosine (I) is hydrolyzed and subsequently coupled with the alkyl halides (II) to produce the N‐alkyl formamide derivatives (III).
ChemInform Abstract: 5‐Fluorouracil Derivatives. Part 17. Synthesis and Antitumor Activity of 5′‐O‐Acyl‐5‐fluorouridines.
Authors: OZAKI S. , AKIYAMA T. , IKE Y. , MORI H. , HOSHI A. 
Published: May 2016

AbstractThe isopropylidene fluorouridine (I) reacts with acyl chlorides such as (II) to give the corresponding esters (III) which are deprotected to produce the compounds (IV) mentioned in the title.
ChemInform Abstract: New Preparative and Optical Resolution Method for β‐Lactams.
Authors: TODA F. , TANAKA K. , YAGI M. , STEIN Z. , GOLDBERG I. 
Published: May 2016

AbstractIrradiation of a 1:1 inclusion compound of the oxamides (I) and TBD gives the lactones (II) selectively in good yields.
ChemInform Abstract: Total Syntheses of 9‐Oxaanthracyclines.
Authors: VAN H. D.‐T. , SEGUIN E. , TILLEQUIN F. , MONNERET C. , KOCH M. 
Published: May 2016

AbstractThe quinizarine derivative (I) is methylated and then coupled with the allyl bromide (III) to give the allyl ether (IV).
ChemInform Abstract: Unexpected Reaction Between DCC and Cephalosporanic Acid Sulfones.
Authors: ALPEGIANI M. , BISSOLINO P. , ARLANDINI E. , BORGHI D. , PERRONE E. 
Published: May 2016

AbstractThe cephemcarboxylic acid dioxide (I) reacts with dicyclohexylcarbodiimide (II) in dichloromethane to yield the spirooxoazetidinylcephem dioxide (III).
ChemInform Abstract: The Use of Phosphate to Generate H Atoms at pH 5‐8 as Determined by Photocurrents: Electrochemical Properties of H Atoms.
Authors: O'NEILL P. , BUSI F. , CONCIALINI V. , TUBERTINI O. 
Published: May 2016

AbstractThe electrochemical properties of H atoms at near‐neutral pH (5‐8) are investigated based upon photocurrents following the interaction of eaq‐ with H2PO4‐ and HPO42‐ in aqueous solution.
ChemInform Abstract: Promoter Effect of Alkali Metal Oxides and Alkaline Earth Metal Oxides on Active Carbon‐Supported Ruthenium Catalyst for Ammonia Synthesis.
Authors: AIKA K. , KAWAHARA T. , MURATA S. , ONISHI T. 
Published: May 2016

AbstractIn order to prepare an effective catalyst for ammonia synthesis, the promotion behavior of alkali and alkaline earth metal nitrates on carbon‐supported Ru catalysts is investigated.
ChemInform Abstract: Dealumination of ZSM‐5; Characterization by DTA/DTG, XPS, and Adsorption Measurements.
Authors: ALSDORF E. , FEIST M. , GROSS TH. , JERSCHKEWITZ H.‐J. , LOHSE U. , SCHWIEGER M. 
Published: May 2016

AbstractThe Si/Al ratios in ZSM‐5 zeolites can be modified by dealumination after hydrothermal synthesis.
ChemInform Abstract: Ni(0)‐Induced and ‐Catalyzed C‐C Bond Formation Between Phenylisocyanate and Vinyl‐Substituted Heteroaromatics.
Authors: HOBERG H. , GUHL D. , BETZ P. 
Published: May 2016

AbstractAzanickelacycles of type V) are the presumed intermediates in Ni‐catalyzed C‐C bond formations between alkenes and isocyanates.
ChemInform Abstract: π‐Face Selectivity of Coordinated Ketones to Nucleophilic Additions: The Importance of Aluminum‐Oxygen π‐Bonding.
Authors: POWER M. B. , BOTT S. G. , ATWOOD J. L. , BARRON A. R. 
Published: May 2016

AbstractThe X‐ray investigation of the Lewis acid‐base complex (IIIa) ( P21/n, Z=4) shows that the ketone in these complexes (8 examples) coordinates such that the Al is in the nodal plane of the C=O π‐bond.
ChemInform Abstract: Carboalumination of 1‐Alkynes and in situ Transmetalation to Higher Order Cyanocuprates. Stereospecific Synthesis of Tri‐ and Disubstituted Olefins by Conjugate Addition to Enones.
Authors: IRELAND R. E. , WIPF P. 
Published: May 2016

AbstractThe terminal alkynes (III) are methylaluminated with trimethylaluminum (II) and then directly transmetalated with the organocuprate (IV) to generate the vinylic cuprates (V).
ChemInform Abstract: Tandem Cyclization‐Cycloaddition Reaction of Rhodium Carbenoids. Scope and Mechanistic Details of the Process.
Authors: PADWA A. , FRYXELL G. E. , ZHI L. 
Published: May 2016

AbstractTreatment of 1‐diazo‐2,5‐pentanediones such as (I) with rhodium(II) carboxylates affords cyclic carbonyl ylide dipoles (III), which undergo 1,3‐dipolar cycloaddition with both electron‐deficient and electron‐rich dipolarophiles as well as with carbonyl compounds to give adducts such as (IV), (VI), (VII), (IX) or (X).
ChemInform Abstract: Diheterocyclic Compounds from Dithiocarbamates and Derivatives Thereof. Part 1. 2,2′‐(Arylenediamino)bisbenzoazoles, 2,2′‐(Arylenediamino)bis(imidazopyridines) and 8,8′‐(Arylenediamino)bispurines.
Authors: GARIN J. , MELENDEZ E. , MERCHAN F. L. , MERINO P. , ORDUNA J. , TEJEDOR R. , TEJERO T. 
Published: May 2016

AbstractThe title compounds, e.g. (III)‐(V) are prepared in one step by the same method as exemplified in the scheme for (III).
ChemInform Abstract: Studies on Formation of 1‐Aralkyl‐2‐aryl‐6‐benzoylbenzimidazoles from 4‐Benzoyl‐o‐phenylenediamine and Aromatic Aldehydes.
Authors: VENKATARATNAM R. V. , RAO P. S. , NARASAIAH B. , RAO M. P. 
Published: May 2016

AbstractThe condensation reaction of the diamine (I) with aromatic aldehydes leads to formation of the benzimidazoles (V) besides the normal products (IV).
ChemInform Abstract: N‐Hydroxypyridine‐2‐thione Carbamates. Part 6. Functionalization of Carbon Radicals Formed by Aminium Cation Radical Cyclizations.
Authors: NEWCOMB M. , MARQUARDT D. J. , KUMAR M. U. 
Published: May 2016

AbstractThe title PTOC carbamates (I) or (IV) serve as precursors of aminium cation radicals, which undergo radical cyclization and subsequent trapping of the thereby formed cyclic carbon radicals.
ChemInform Abstract: “Accordion” Rearrangements of Cyclobutane α‐Sulfonyl Lactones.
Authors: KENDE A. S. , KALDOR I. 
Published: May 2016

AbstractStarting with the ethoxycarbonylmethylcyclobutanone (I), the tricyclic α‐sulfonyl γ‐lactones (IX) and (XIV) are prepared.
ChemInform Abstract: An Annulation Method for the Synthesis of Highly Substituted Polycyclic Aromatic and Heteroaromatic Compounds.
Authors: DANHEISER R. L. , BRISBOIS R. G. , KOWALCZYK J. J. , MILLER R. F. 
Published: May 2016

AbstractA general strategy for the synthesis of highly substituted polycyclic aromatic and heteroaromatic compounds such as (III), (VI), (VIII) or (IX) is reported.
ChemInform Abstract: Selective Desulfurization of 1,3‐Dithianes, 1,3‐Oxathiolanes, and 1,3‐Thiazolidines by Tributyltin Hydride.
Authors: SCHMIDT K. , O'NEAL S. , CHAN T. C. , ALEXIS C. P. , URIBE J. M. , LOSSENER K. , GUTIERREZ C. G. 
Published: May 2016

AbstractThe thiazolidine (IIIa), the oxathiolanes (IIIb) ‐ (IIId), and the 1,3‐dithianes (IIIe) and (IIIf), derived from the aldehydes or ketones (I), are cleaved with tributyltin hydride (IV) to form the stannyl sulfides (V), together with the desulfurized derivatives (VI).
ChemInform Abstract: Bornanesultam‐Directed Asymmetric Synthesis of Crystalline, Enantiomerically Pure Syn Aldols.
Authors: OPPOLZER W. , BLAGG J. , RODRIGUEZ I. , WALTHER E. 
Published: May 2016

AbstractThe N‐acylsultams (I) are converted, via aldol reaction with the aldehydes (II), into the diastereomerically pure, crystalline syn aldols (III) or (VI); the absolute configuration of the products is controlled by the choice of the enolate counterion (B → (III), Sn → (VI)).
ChemInform Abstract: Phase Transfer Catalysed Alkylation of 4‐Hydroxycoumarin ‐ Synthesis of α,α‐Disubstituted o‐Hydroxyacetophenones.
Authors: MAJUMDAR K. C. , KHAN A. T. , CHATTOPADHYAY S. K. 
Published: May 2016

AbstractThe title reaction of (I) with active bromides gives O‐alkylated products (cf.
ChemInform Abstract: Synthetically Useful β‐Lithioalkoxides from Reductive Lithiation of Epoxides by Aromatic Radical Anions.
Authors: COHEN T. , JEONG I.‐H. , MUDRYK B. , BHUPATHY M. , AWAD M. M. A. 
Published: May 2016

AbstractVarious oxiranes are subjected to cleavage via reductive lithiation with lithium 4,4'‐di‐tert‐butylbiphenylide.
ChemInform Abstract: Alkyl‐ and Arylsulfenanilides by Cycloelimination of Alkenes from Sulfimides. Part 2. Thermolysis of 3‐Alkylthio‐propionitrile‐ or Methyl 3‐Alkylthio‐propanoate S‐(N‐Aryl)imides.
Authors: FRANEK W. , CLAUS P. K. 
Published: May 2016

AbstractA series of title compounds such as (III) are prepared by a simple route starting from suitable sulfides (I).
ChemInform Abstract: Studies on the Synthesis of the Antitumor Agents Esperamicin A1/Calicheamicin γ1: Stereospecific Synthesis of the 12β‐Hydroxybicyclo‐(7.3.1)tridecenediyne Core Structure via a Co2(CO)6‐Acetylene‐Mediated Synclinal Aldol Reaction.
Authors: MAGNUS P. , ANNOURA H. , HARLING J. 
Published: May 2016

AbstractThe enediynal (II), prepared from the trimethylsilylacetylene (I) in five steps, is treated with dicobalt octacarbonyl (III) to give the complex (IV).
ChemInform Abstract: Aromatic Substitution. Part 58. Boron Tris(triflate) Catalyzed Adamantylation of Benzene and Toluene with 1‐ and 2‐Haloadamantanes and Adamantanoyl Chlorides. Isomerization of Phenyl‐ and Tolyladamantanes.
Authors: OLAH G. A. , FAROOQ O. , FARNIA S. M. F. , WU A.‐H. 
Published: May 2016

AbstractThe 1‐haloadamantanes (I) and (VIII) are coupled with toluene (II) or mixtures of (II) and benzene (IX) in the presence of boron triflate to produce mixtures of regioisomeric adamantylarenes.
ChemInform Abstract: Stereoselective Construction of Quaternary Carbons by the Reaction of Aldehydes with Allylic Chromium Reagents Prepared from 1,3‐Diene Monoepoxides and CrCl2.
Authors: FUJIMURA O. , TAKAI K. , UTIMOTO K. 
Published: May 2016

AbstractThe 1,3‐diene monoepoxides (I) are coupled with aldehydes such as (II) in the presence of CrCl2 and LiI to give predominantly the 1,3‐diols (III).
ChemInform Abstract: Facile Synthesis of 1,1′‐Binaphthyl‐2‐carboxylates via Nucleophilic Aromatic Substitution of 1‐Methoxy‐2‐naphthoic Esters by 1‐Naphthyl Grignard Reagents.
Authors: HOTTA H. , SUZUKI T. , MIYANO S. 
Published: May 2016

AbstractThe 1‐naphthyl Grignard compounds (I) are coupled with the 1‐methoxynaphthoates (II) to form the 1,1'‐binaphthyl derivatives (III).
ChemInform Abstract: The Acid Chloride‐Imino Ester Condensation: A Direct Approach to PS‐5 and PS‐6 Intermediates and Related Compounds.
Authors: PALOMO C. , ONTORIA J. M. , ODRIOZOLA J. M. , ALZPURUA J. M. , GANBOA I. 
Published: May 2016

AbstractReaction of the acid chlorides (I) and (VI) with the α‐imino carboxylate (II) results in cycloaddition to produce the β‐lactams (III) or a mixture of the diastereomeric β‐lactams (VII) and (VIII).
ChemInform Abstract: 1,3‐Benzodioxole Derivatives as Radioprotective Agents. Part 3. 5‐Hydroxy‐1,3‐benzodioxole Ethers and Their Rearrangement Products.
Authors: DALLACKER F. , HOLSCHBACH M. , KONINGS A. W. T. 
Published: May 2016

AbstractAllylation of 5‐hydroxy‐1,3‐benzodioxole (I) with bromides such as (II) gives the corresponding allyl ethers, e.g. (III).
ChemInform Abstract: Diheterocyclic Compounds from Dithiocarbamates and Derivatives Thereof. Part 2. 2,2′‐Diamino‐6,6′‐bibenzoazoles.
Authors: GARIN J. , MELENDEZ E. , MERCHAN F. L. , MERINO P. , ORDUNA J. , TEJERO T. 
Published: May 2016

AbstractThe readily available dithiocarbamates (II) and dithiocarbonimidates (IV) afford in one step the title compounds (III) or (V).
ChemInform Abstract: Reaction of N‐(4‐Pyridylmethyl)benzamide N‐Oxides and N‐((α‐Acetoxy)‐4‐pyridylmethyl)benzamides with 1,3‐Diphenyl‐1,3‐propanedione.
Authors: BRANA M. F. , LOPEZ RODRIGUEZ M. L. , CASTELLANO J. M. , FERNANDEZ P. , GARRIDO‐PERTIERRA A. 
Published: May 2016

AbstractWhereas the reaction of the N‐oxides (I) with the dione (III) in the presence of Ac2O gives the compounds (IV) only in low yield, a better yield of (IV) is obtained by reaction of the acetoxy derivatives (II) derived from (I) with (III).
ChemInform Abstract: Synthesis and Transformations of 2‐Ethoxycarbonyl‐3‐isothiocyanatopyridine. Pyrido(3,2‐d)pyrimidines and Some Azolopyrido(3,2‐d)pyrimidines.
Authors: URLEB U. , STANOVNIK B. , TISLER M. 
Published: May 2016

AbstractThe title compound (I) having an ester group ortho to the isothiocyanate group is prepared by reaction of the 3‐amino analogue with thiophosgene.
ChemInform Abstract: 1‐Hydroxy‐3‐amino‐2‐piperidone (δ‐N‐Hydroxycycloornithine) Derivatives: Key Intermediates for the Synthesis of Hydroxamate‐Based Siderophores.
Authors: KOLASA T. , MILLER M. J. 
Published: May 2016

AbstractThe pyroglutamic acid (I) is N‐protected and then cleaved to give the glutamic acid (III) which is reduced to produce the hydroxynorvaline derivative (IV).
ChemInform Abstract: 5‐Oxo‐1,4‐dihydroindenopyridines: Calcium Modulators with Partial Calcium Agonistic Activity.
Authors: ROSE U. 
Published: May 2016

AbstractThe title compounds (IV), prepared by a one‐pot procedure by Knoevenagel condensation of 1,3‐indandione (I) and the aromatic aldehydes (II) followed by cyclizing Michael addition of methyl β‐aminocrotonate (III), are screened for their pharmacological activity.
ChemInform Abstract: Methodology for the Enantioselective Synthesis of Aldols and Other 1,3‐Dioxygenated Systems.
Authors: IRELAND R. E. , WIPF P. , MILTZ W. , VANASSE B. 
Published: May 2016

AbstractCoupling of the hydroxymethylfuran (II) with the chiral glycidol ether (S)‐(I), followed by oxidative rearrangement and acetalization, gives stereoselectively the spiro‐fused cyclic enones (VI).
ChemInform Abstract: Synthesis of 4(6)‐tert.‐Butylpyrimidines from 4(6)‐Halopyrimidines by Using Higher‐Order Lithium and Magnesium Organocuprate Reagents.
Authors: EVANS R. F. , SAVAGE G. P. , GOUGH D. A. 
Published: May 2016

AbstractThe mixed higher‐order organocuprate (II), formed by adding of 2 equiv. BuLi to 1 equiv. of CuCN, is used to prepare the 4,6‐di‐tert.‐butylpyrimidines (III) from the readily available iodo‐pyrimidines (I).
ChemInform Abstract: Synthesis and Cardiotonic Activity of Pyrimido(5,4‐b)(1,4)oxazinones and 1,4‐Dioxino(2,3‐d)pyrimidines.
Authors: MATYUS P. , MAKK N. , TEGDES A. , KOSARY J. , KASZTREINER E. , PODANYI B. , RABLOCZKY G. , KUERTHY M. + 
Published: May 2016

AbstractNew pyrimidooxazinones such as (IV), (VI), (IX) and (XI) and the novel ring system contained in (XIV)/(XV) are prepared.
ChemInform Abstract: A New Approach for the Synthesis of Pteridines: The Synthesis of 3‐Substituted‐2‐thioxo‐1,2‐dihydro‐4(3H)‐pteridinones.
Authors: URLEB U. , NEIDLEIN R. , KRAMER W. 
Published: May 2016

AbstractThe title compounds (V) (11 examples) are prepared by condensation of the carboxylate (III) with the amino compounds such as (IV) in EtOH.
ChemInform Abstract: Dithiatopazine and Related Systems. Synthesis, Chemistry, X‐Ray Crystallographic Analysis and Calculations.
Authors: NICOLAOU K. C. , DEFREES S. A. , HWANG C.‐K. , STYLIANIDES N. , CARROLL P. J. , SNYDER J. P. 
Published: May 2016

AbstractThe title compound (II) shows an intriguing chemistry including a number of skeletal rearrangements, S‐S bond ruptures and sulfur‐transfer reactions as shown in the scheme.
ChemInform Abstract: Synthesis of Two Noninterconvertible Conformers of a Single Host. Self‐Filled and Vaulted Cappedophanes.
Authors: VINOD T. K. , HART H. 
Published: May 2016

AbstractThe tetrathiol (I) reacts with the tetrabromide (II) to give either the self‐filled (autophagous) cyclophanes (III) or the vaulted cyclophanes (IV).