bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between self-serving leadership and employees’ expediency: a moderated mediation model
Authors: Yuan Xiaolong , Yang Yongyong , Wang Feng , Ding Qian , Deng Mianlin , Shi Wendian , Zhao Xudong 
Published: October 2024

PurposeDrawing upon social information processing theory, this study investigates the correlation between self-serving leadership and employee expediency. It also explores the mediating effect of self-interest motivation and the moderating effect of trait mindfulness.Design/methodology/approachA total of 147 part-time MBA students were enlisted to participate in a scenario experiment (Study 1), and 291 valid employee questionnaires were collected through a multiple-time point survey (Study 2). SPSS 23.0, MPLUS 8.0 and PROCESS programs were used to analyze the data and test the hypotheses.FindingsStudy 1 illustrated a positive correlation between self-serving leadership and employee expediency. It also identified self-interest motivation as a mediating factor in the correlation between self-serving leadership and expediency. Study 2 replicated the results obtained in Study 1 and expanded upon them by demonstrating that trait mindfulness moderates the association between self-serving leadership and self-interest motivation. Additionally, trait mindfulness moderates the indirect effect of self-serving leadership on expediency.Practical implicationsThis research argues that organizations should take steps to prevent self-serving leadership in order to reduce employee expediency. Furthermore, it is advisable to provide ethics training to employees who exhibit high trait mindfulness, as they show increased sensitivity to self-serving leadership and are more likely to engage in unethical behavior.Originality/valueThis study expands the existing research on the ethical outcomes of self-serving leadership and contributes to a deeper understanding of the negative aspects of trait mindfulness.
Fashionable altruism: the marketing of fashion-based social enterprise
Authors: Hewitt Jon , Parker Lukas , McQuilten Grace , Bigolin Ricarda 
Published: October 2024

Purpose
This paper aims to understand how fashion-based social enterprises (FSEs) navigate the marketing communications of fashion products alongside those of their social mission. The authors use the theoretical lens of Consumer culture theory, Collin Campbell’s “Romantic ethic” and the work of Eva Illouz to explore how FSEs weave the emotional appeals of fashion consumption with those of contributing to a greater social cause. The melding of these theoretical approaches to consumer behaviour enables a thorough analysis of FSE marketing strategies.

Design/methodology/approach
Semi-structured in-depth interviews were conducted with 16 founders, marketing directors and managers of FSEs. Open-ended questions were used, and key themes were established through inductive analysis.

Findings
The findings show that FSEs use a form of brand storytelling in their marketing communications; they view their social mission as a unique selling point; FSEs could further incorporate product quality/aesthetic value into brand storytelling; and they could sharpen brand storytelling by further engaging with the positive emotional responses they elicit from consumers.

Originality/value
This research has both theoretical and practical implications in that FSEs that focus on explicit altruistic messaging at the expense of aesthetic hedonism may limit their appeal to mainstream fashion consumers. Accordingly, a promising approach may be to effectively incorporate and link the positive emotional responses of both altruistic and aesthetic value. This approach could similarly apply to other areas of social enterprise retail marketing, particularly for those seeking to attract consumers beyond ethical shoppers.
The involvement of multiple ABC transporters in daunorubicin efflux in Streptomyces coeruleorubidus
Authors: Dong Jianxin , Ning Jiali , Tian Yu , Li Han , Chen Hua , Guan Wenjun 
Published: October 2024

AbstractStreptomyces genus produces a large number of antibiotics, which are always synthesized by specific biosynthetic gene clusters (BGCs). To resist autotoxicity, transporters encoded by genes located within BGC occasionally pump antibiotic along with transporter encoded by gene located outside BGC. Daunorubicin is an anthracycline antibiotic biosynthesized by Streptomyces species, playing a crucial role in the treatment of leukaemia. In existing studies, only one two‐component ATP‐binding cassette (ABC) transporter, encoded by drrA1‐drrB1 (abbreviated as drrAB1) and located within the daunorubicin BGC, has been proven to extrude daunorubicin. In this work, two other two‐component ABC transporters, encoded by drrAB2 and drrAB3 and located outside the cluster, were found to play the complementary role in daunorubicin efflux in S. coeruleorubidus. Disruption of three drrABs resulted in a 94% decrease in daunorubicin production. Furthermore, drrAB2 is regulated by the TetR family regulator DrrR1, responding to the intracellular accumulation of daunorubicin and suggesting its role in stress response and self‐resistance. Although the homologues of DrrAB1 are only found in three anthracycline BGCs, the homologues of DrrAB2 and DrrAB3 are spread in many Streptomyces strains which do not contain any known anthracycline BGC. This indicates that DrrAB2 and DrrAB3 may recognize and extrude a broader range of substrates besides daunorubicin, thus playing a more extensive role in cellular detoxification.
Norm modification and the responsibility to protect: Towards a four‐pillar framework
Authors: Peak Thomas 
Published: October 2024

AbstractThe Responsibility to Protect (RtoP) faces intense contestation. Within a rapidly evolving world order, this is only likely to increase. And absent substantive norm modification to (re‐)establish genuine consensus over the meaning of the norm, RtoP faces imminent weakening. This paper suggests one such avenue of modification: reimagining RtoP's structure across four pillars instead of the existing three. It disaggregates the existing third pillar across two pillars: a new fourth‐pillar which contains the last resort use of collective force, in‐line with the UN Charter, and a third‐pillar which retains the existing non‐forcible dimensions of the international responsibility to respond. This new four‐pillar RtoP poses three distinct advantages. It increases the potential for peaceful international responses to mass atrocity by addressing the wide‐spread tendency to conflate the entire international responsibility to respond with the last‐resort use of force; it opens broader space for reconciling divergent global perspectives on the use of force, highlighting the collective and last‐resort nature of legitimate military enforcement; and it resolves additional points of contestation over RtoP including whether the pillars are sequential or mutually reinforcing.
A missense mutation in the tyrosinase gene explains acromelanism in domesticated canaries
Authors: Guimarães‐Moreira Margarida , Marques Cristiana I. , Afonso Sandra , Lacerda Beatriz , Carneiro Miguel , Araújo Pedro M. 
Published: October 2024

AbstractAcromelanism is a form of albinism observed in several vertebrate species. In mammals, acromelanism is known to be caused by mutations in the tyrosinase gene (TYR) that induce a temperature‐sensitive behavior of melanin synthesis, resulting in a characteristic hair color gradient. In birds, several phenotypes consistent with acromelanism have been reported, but their genetic basis remains unknown. This study aimed to identify the genetic basis of an acromelanistic phenotype in domesticated canaries known as pearl and test whether it is caused by the same molecular mechanism described for mammals. To do this, we compared the genomes of pearl and non‐pearl canaries and searched for potentially causative genetic mutations. Our results suggest that the pearl phenotype is caused by a mutation in the TYR gene encoding a TYR‐P45H missense substitution. Our findings further suggest that reports of acromelanism in other bird species might be explained by TYR mutations.
Anti‐factor Xa and activated partial thromboplastin time strategies for unfractionated heparin dosing after HeartMate 3 left ventricular assist device implantation
Authors: Feng Iris , Kurlansky Paul A. , Powley Tanner R. , Hynds Melissa A. , Yang Christine G. , Eisenberger Andrew , Hastie Jonathan M. , Sutherland Lauren D. , Yuzefpolskaya Melana , Colombo Paolo C. , Sayer Gabriel T. , Uriel Nir Y. , Naka Yoshifumi , Takeda Koji 
Published: October 2024

AbstractBackgroundNo clear guidelines exist for perioperative anticoagulation management after durable left ventricular assist device insertion. In this study, we sought to compare outcomes between anti‐factor Xa (FXa) and activated partial thromboplastin time (aPTT) in monitoring unfractionated heparin (UFH) dosing after HeartMate 3 (HM3) insertion.MethodsThis is a single‐center retrospective review of patients who received UFH after HM3 insertion between 01/2020–12/2022. Post‐operative UFH dose was titrated by aPTT goal 45–60 sec (n = 53) or FXa goal 0.1–0.2 U/mL (n = 59). Baseline differences between cohorts were balanced by inverse probability treatment weighting.ResultsAt baseline, unadjusted FXa patients were more likely to be white (47.5% vs. 35.8%, p < 0.001), INTERMACS 1–2 (69.5% vs. 47.2%, p = 0.013), have history of coronary artery disease (66.1% vs. 43.4%, p = 0.026), and lower eGFR (54.1 vs. 63.7 mL/min/1.73 m2, p = 0.029) compared to the aPTT group. After adjusting for several bleeding/thrombosis risk factors, 97.5% of FXa and 91.0% of aPTT patients reached therapeutic levels with comparable UFH duration and maximum dose. Moreover, in‐hospital mortality (2.5% vs. 3.1%, p = 0.842), major bleeding events (4.2% vs. 9.2%, p = 0.360), and thromboembolic events (21.8% vs. 10.1%, p = 0.151) remained without significant differences between FXa and aPTT cohorts. There was a high degree of variability in FXa (r2 = 0.20) and aPTT (r2 = 0.22) values for any given UFH dose.ConclusionsNo differences in frequency of bleeding or thromboembolic events were observed in this study between FXa versus aPTT cohorts after HM3 implantation. More longitudinal studies are warranted to determine whether or not one assay is superior to the other.
The Immigration‐Related Political Ideology Scale: Development, factor structure, and validity evidence
Authors: Schwartz Seth J. , Duque Maria , Sahbaz Sumeyra , Gladfelter Carolina Scaramutti , Cisco Mia , Nehme‐Kotocavage Lea , Vo Duyen H. , Alpysbekova Aigerim , Montero‐Zamora Pablo , Ertanir Beyhan , Coninck David De , Bogado Natalia , Schildkraut Deborah J. 
Published: October 2024

AbstractThe aim of the present study was to develop and validate the Immigration‐Related Political Ideology Scale (IRPIS), designed to measure diverse political perspectives on immigration among US voters. The IRPIS was developed following a series of focus groups and refined through a systematic item‐generation process involving expert panels. The scale was validated using a two‐step factor analysis with a nationally representative sample of 1292 US voters, divided into exploratory (n = 632) and confirmatory (n = 660) sub‐samples. The exploratory factor analysis identified seven distinct factors: conservative views, welcoming attitudes, world regions, flexibility, assimilationist expectations, multicultural expectations, and undocumented immigrant rights. Confirmatory factor analysis provided an acceptable fit (CFI = .901; RMSEA = .050), and the scale demonstrated high internal consistency (Cronbach's alphas ranging from .89 to .97). Inter‐factor correlations varied, with strong links observed among welcoming attitudes, flexibility, and multicultural expectations (r’s > .80), confirming a polarization between liberal and conservative stances on immigration. These findings suggest that the IRPIS is the first scale specifically designed to assess immigration‐related political orientations in a polarized US context. This tool has important implications for political strategy and policymaking, especially in the context of rising immigration rates and political polarization.Public Significance StatementThe present study validates the Immigration‐Related Political Ideology Scale (IRPIS) using a nationally representative sample of 1292 US voters. Immigration remains a highly polarizing issue, with deeply entrenched ideological differences influencing policy preferences and public discourse. Exploratory factor analysis identified seven distinct factors and confirmed a clear polarization between liberal and conservative views on immigration. The IRPIS represents a critical tool for research, political strategy, and policymaking.
Analysis of the transformation of demand willingness for housing reverse mortgages in China based on a scenario simulation experiment
Authors: Han Wei , Zhang Bo 
Published: October 2024

AbstractAs the population rapidly ages, Housing Reverse Mortgages (HRMs) have emerged as a valuable addition to the multilevel pension insurance system, helping to alleviate the pressure on pension financing. However, the HRM market in China faces challenges due to the limited financial literacy among middle‐aged and elderly residents; there is a “cognitive bias” toward understanding the mechanisms and benefits of HRMs leading to “insufficient effective demand.” This study empirically investigates the likelihood of changing the “demand willingness” for an HRM through a scenario‐simulation experiment focused on HRM‐related information disclosure. The findings include: (1) Up to 46.78% of the subjects' attitudes toward adopting HRMs shifted from “unwilling” to “willing” after receiving disclosed information, indicating that cognitive bias significantly impacts the insufficient effective demand for these housing products. The information disclosure experiment can correct the inadequate financial literacy to a certain extent, thereby significantly enhancing the potential demand willingness. (2) After the experiment, subjects with strong motives to bequeath their property to family members (referred to as “strong bequest motives”) significantly changed their willingness to adopt HRMs (“demand willingness”). This suggests that a clear, comprehensive promotional strategy can better align middle‐aged and elderly residents' perceptions of the role of HRMs in protecting inheritances, reducing the impact of bequest‐related considerations on their financial decisions. (3) Participants initially exhibiting lower financial literacy also demonstrated notable shifts in their demand willingness postexperiment. Access to easily understood, high‐quality information appears to help older individuals recognize the potential benefits of HRMs, mitigating the negative effects of cognitive limitations on their decision‐making. These findings highlight the importance of enhancing financial literacy and promoting a better understanding of HRMs among middle‐aged and elderly individuals, which may effectively manage the challenges associated with an aging population and the pressures on pension financing.
Publics' Expectation Toward Ethical Leadership and Ethical Corporate Social Responsibility (CSR): Evidence From the U.S. and South Korea
Authors: Park Keonyoung , Rim Hyejoon 
Published: October 2024

ABSTRACTDespite continuous academic attempts to investigate the relationship between public expectations of ethical leadership and corporate social responsibility (CSR) efforts, little research has demonstrated the subliminal process of the relationship. This study focuses on the publics' power distance perceptions as a key driver to lead individuals to prioritize CSR, mediated by the expectations of corporate ethical leadership. To further understand the mechanism and the way power distance perception influences public attitudes toward CSR operations, this study suggests a theoretical model illustrating the relationships among power distance perception, expectancy of ethical leadership, expectancy of ethical CSR, and willingness to support socially responsible companies. A cross‐national survey was conducted to provide empirical evidence from the United States (U.S.) and South Korea. Given that strategic approaches of CSR prioritize meeting public expectations toward corporate social roles, this study provides meaningful implications on public relations practice and CSR scholarship by demonstrating how public expectations of corporate ethical operations are shaped and how these expectations influence the public evaluation of corporate behaviors.
The effects of social exclusion on distributive fairness judgements and cooperative behaviour
Authors: Sun Qian , Molenmaker Welmer E. , Liu Yongfang , van Dijk Eric 
Published: October 2024

AbstractIn this article, we investigate how being socially excluded (vs. included) affects people's distributive fairness judgements and their willingness to cooperate with others in subsequent interactions. For this purpose, we conducted three experiments in which we assessed individual differences in having experienced being socially excluded (Experiment 1, N = 164), and manipulated social exclusion (Experiment 2, N = 120; Experiment 3, N = 492). We studied how this impacted fairness judgements of three different outcome distributions (disadvantageous inequality, advantageous inequality, and equality) both within‐participants (Experiments 1 and 2) and between‐participants (Experiment 3). To assess behavioural consequences, we then also assessed participants' cooperation in a social dilemma game. Across the three experiments, we consistently found that social exclusion impacted fairness judgements. Compared to inclusion, excluded participants judged disadvantageous inequality as more unfair and advantageous inequality as less unfair. Moreover, compared to socially included participants, socially excluded participants were more willing to cooperate after experiencing advantageous rather than disadvantageous inequality, and feelings of acceptance served as a mediator in these associations.
Switching costs in transient technology use: Panel evidence from Kenyan maize production
Authors: Chen Maolong , Hu Chaoran , Myers Robert J. 
Published: October 2024

AbstractThe idea of switching costs and how they affect agricultural technology adoption has received little attention in the literature. We employ a dynamic switching model to show that switching costs generally discourage the adoption of new technologies by farmers, but the extent of the effect depends on the level of switching costs, as well as farmer perceptions and foresight. We provide an empirical strategy to identify switching costs and estimate their effects on adoption under different farmers’ perceptions about adoption uncertainty. An application to hybrid seed adoption in Kenya confirms the existence of switching costs. The correlated‐random‐effects probit results suggest there is heterogeneity in dominant farmer types across agro‐ecological zones in Kenya. Area‐specific policies are suggested to promote technology adoption in different environments.
Maternal infection with SARS‐CoV‐2 during early pregnancy induces hypoxia at the maternal–fetal interface
Authors: Shi Xiaohui , Xi Chenxiang , Dong Baoxing , Yan Zihui , Liu Wenqiang , Gao Shaorong , Chen Di 
Published: October 2024

AbstractThe coronavirus disease 2019 (COVID‐19) pandemic increases the risk of adverse fetal outcomes during pregnancy. Maternal infection during pregnancy, particularly with cytomegalovirus (CMV), hepatitis B and C virus, and human immunodeficiency virus can have detrimental effects on both mother and fetus, potentially leading to adverse outcomes such as spontaneous abortion or neonatal infection. However, the impact of severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) infection on the maternal–fetal interface remains poorly understood. In this study, we initially utilised immunofluorescence and immunohistochemical to investigate placental samples from pregnant women who were infected with SARS‐CoV‐2 during the first trimester. Our data indicate that infection in the first trimester induces an upregulation of hypoxia inducible factor (HIF) levels at the maternal–fetal interface. Subsequently, single‐cell RNA sequencing and metabolomics sequencing analyses reveal alterations in maternal–fetal interface. Remarkably, immune cells exhibited low expression levels of HIF possibly associated with immune activation. Furthermore, our findings demonstrate a gradual reduction in transcriptome and metabolic changes as gestation progressed beyond 12–16 weeks compared to samples obtained at 6–8 weeks gestation. Overall, our study suggests that early‐stage SARS‐CoV‐2 infection during the first trimester leads to severe hypoxia and aberrant cell metabolism at the maternal–fetal interface which gradually resolves as pregnancy progresses. Nevertheless, these abnormal changes may have long‐term implications for maternal–fetal interface development.
Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids
Authors: Zhang Laihai , Jiang Yun , Jia Wenwen , Le Wenjun , Liu Jie , Zhang Peng , Yang Huangtian , Liu Zhongmin , Liu Yang 
Published: October 2024

AbstractCurrent therapeutic drug exploring targeting at myocardial ischemia/reperfusion (I/R) injury is limited due to the lack of humanized cardiac models that resemble myocardial damage and inflammatory response. Herein, we develop ventricular cardiac organoids from human induced pluripotent stem cells (hiPSCs) and simulate I/R injury by hypoxia/reoxygenation (H/R), which results in increased cardiomyocytes apoptosis, elevated oxidative stress, disrupted morphological structure and decreased beat amplitude. RNA‐seq reveals a potential role of type I interferon (IFN‐I) in this I/R injury model. We then introduce THP‐1 cells and reveal inflammatory responses between monocytes/macrophages and H/R‐induced ventricular cardiac organoids. Furthermore, we demonstrate Anifrolumab, an FDA approved antagonist of IFN‐I receptor, effectively decreases IFN‐I secretion and related gene expression, attenuates H/R‐induced inflammation and oxidative stress in the co‐culture system. This study advances the modelling of myocardial I/R injury with inflammatory response in human cardiac organoids, which provides a reliable platform for preclinical study and drug screening.