bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measurement Invariance of the Serbian Version of the Satisfaction	With Life Scale Across Age, Gender, and Time
Authors: Jovanović Veljko 
Published: June 2017

Abstract. The present research aimed at examining measurement invariance of the Serbian version of the Satisfaction with Life Scale (SWLS) across age, gender, and time. A total sample in Study 1 consisted of 2,595 participants from Serbia, with a mean age of 23.79 years (age range: 14–55 years). The final sample in Study 2 included 333 Serbian undergraduate students ( Mage = 20.81; age range: 20–27 years), who completed the SWLS over periods of 6 and 18 months after the initial assessment. Confirmatory factor analysis (CFA) supported the modified unidimensional model of the SWLS, with correlated residuals of items 4 and 5 tapping past satisfaction. The results of the multigroup confirmatory factor analysis supported the full scalar invariance across gender and over time and partial scalar invariance across age. Latent mean comparisons revealed that women reported higher life satisfaction than men. Additionally, adolescents reported higher life satisfaction than students and adults, with adults showing the lowest life satisfaction. Our findings indicate that the SWLS allows meaningful comparisons in life satisfaction across age, gender, and over time.
The REIm-13
Authors: McGuiness Clare E. , Zajac Ian , Wilson Carlene , Turnbull Deborah 
Published: June 2017

Abstract. The Rational-Experiential Multimodal Inventory (REIm) is a recent tool showing promise in the measurement of self-reported thinking style – preference for rational or experiential processing – and offers three-faceted measurement of the latter. We present the first short form of the measure, the REIm-13, and test its factor structure, reliability, and validity in a large community sample. Participants were N = 920 Australian adults (502 females) who completed an online survey ( N = 510 of whom participated in a follow-up survey). In addition to the REIm, participants completed a Big Five personality measure. The internal consistency of the REIm-13 was acceptable given the limited number of items (.52–.68). Furthermore, test-retest reliability was high (ρ = .64–.74) for the theorized four-factor and two-factor solutions. Construct validity was established by examining the relationship between short-form and full REIm factors (ρ = .65–.71), and the validity of composite scoring was confirmed against factor scoring. Relationship with age (a slight negative relationship to both main scales), gender (females reporting higher Experientiality, males higher Rationality), and Big Five variables largely followed previous findings, demonstrating concurrent validity. The study demonstrates that the REIm-13 provides sound measurement of thinking style.
Neutral and charged inter-valley biexcitons in monolayer MoSe2
Authors: Hao Kai , Specht Judith F. , Nagler Philipp , Xu Lixiang , Tran Kha , Singh Akshay , Dass Chandriker Kavir , Schüller Christian , Korn Tobias , Richter Marten , Knorr Andreas , Li Xiaoqin , Moody Galan 
Published: June 2017

AbstractIn atomically thin transition metal dichalcogenides (TMDs), reduced dielectric screening of the Coulomb interaction leads to strongly correlated many-body states, including excitons and trions, that dominate the optical properties. Higher-order states, such as bound biexcitons, are possible but are difficult to identify unambiguously using linear optical spectroscopy methods. Here, we implement polarization-resolved two-dimensional coherent spectroscopy (2DCS) to unravel the complex optical response of monolayer MoSe2 and identify multiple higher-order correlated states. Decisive signatures of neutral and charged inter-valley biexcitons appear in cross-polarized two-dimensional spectra as distinct resonances with respective ∼20 and ∼5 meV binding energies—similar to recent calculations using variational and Monte Carlo methods. A theoretical model considering the valley-dependent optical selection rules reveals the quantum pathways that give rise to these states. Inter-valley biexcitons identified here, comprising of neutral and charged excitons from different valleys, offer new opportunities for developing ultrathin biexciton lasers and polarization-entangled photon sources.
Ensemble-averaged Rabi oscillations in a ferromagnetic CoFeB film
Authors: Capua Amir , Rettner Charles , Yang See-Hun , Phung Timothy , Parkin Stuart S. P. 
Published: June 2017

AbstractRabi oscillations describe the process whereby electromagnetic radiation interacts coherently with spin states in a non-equilibrium interaction. To date, Rabi oscillations have not been studied in one of the most common spin ensembles in nature: spins in ferromagnets. Here, using a combination of femtosecond laser pulses and microwave excitations, we report the classical analogue of Rabi oscillations in ensemble-averaged spins of a ferromagnet. The microwave stimuli are shown to extend the coherence-time resulting in resonant spin amplification. The results we present in a dense magnetic system are qualitatively similar to those reported previously in semiconductors which have five orders of magnitude fewer spins and which require resonant optical excitations to spin-polarize the ensemble. Our study is a step towards connecting concepts used in quantum processing with spin-transport effects in ferromagnets. For example, coherent control may become possible without the complications of driving an electromagnetic field but rather by using spin-polarized currents.
Coherent manipulation of valley states at multiple charge configurations of a silicon quantum dot device
Authors: Schoenfield Joshua S. , Freeman Blake M. , Jiang HongWen 
Published: June 2017

AbstractQubits based on silicon quantum dots are emerging as leading candidates for the solid-state implementation of quantum information processing. In silicon, valley states represent a degree of freedom in addition to spin and charge. Characterizing and controlling valley states is critical for the encoding and read-out of electrons-in-silicon-based qubits. Here, we report the coherent manipulation of a qubit, which is based on the two valley states of an electron confined in a silicon quantum dot. We carry out valley qubit operations at multiple charge configurations of the double quantum dot device. The dependence of coherent oscillations on pulse excitation level and duration allows us to map out the energy dispersion as a function of detuning as well as the phase coherence time of the valley qubit. The coherent manipulation also provides a method of measuring valley splittings that are too small to probe with conventional methods.
Antibody therapies for the prevention and treatment of viral infections
Authors: Salazar Georgina , Zhang Ningyan , Fu Tong-Ming , An Zhiqiang 
Published: June 2017

AbstractAntibodies are an important component in host immune responses to viral pathogens. Because of their unique maturation process, antibodies can evolve to be highly specific to viral antigens. Physicians and researchers have been relying on such high specificity in their quest to understand host–viral interaction and viral pathogenesis mechanisms and to find potential cures for viral infection and disease. With more than 60 recombinant monoclonal antibodies developed for human use in the last 20 years, monoclonal antibodies are now considered a viable therapeutic modality for infectious disease targets, including newly emerging viral pathogens such as Ebola representing heightened public health concerns, as well as pathogens that have long been known, such as human cytomegalovirus. Here, we summarize some recent advances in identification and characterization of monoclonal antibodies suitable as drug candidates for clinical evaluation, and review some promising candidates in the development pipeline.
Magnetic ground state of SrRuO3 thin film and applicability of standard first-principles approximations to metallic magnetism
Authors: Ryee Siheon , Han Myung Joon 
Published: June 2017

AbstractA systematic first-principles study has been performed to understand the magnetism of thin film SrRuO3 which lots of research efforts have been devoted to but no clear consensus has been reached about its ground state properties. The relative t2g
level difference, lattice distortion as well as the layer thickness play together in determining the spin order. In particular, it is important to understand the difference between two standard approximations, namely LDA and GGA, in describing this metallic magnetism. Landau free energy analysis and the magnetization-energy-ratio plot clearly show the different tendency of favoring the magnetic moment formation, and it is magnified when applied to the thin film limit where the experimental information is severely limited. As a result, LDA gives a qualitatively different prediction from GGA in the experimentally relevant region of strain whereas both approximations give reasonable results for the bulk phase. We discuss the origin of this difference and the applicability of standard methods to the correlated oxide and the metallic magnetic systems.
A Low-cost, Highly-stable Surface Enhanced Raman Scattering Substrate by Si Nanowire Arrays Decorated with Au Nanoparticles and Au Backplate
Authors: Lee Bi-Shen , Lin Ding-Zheng , Yen Ta-Jen 
Published: June 2017

AbstractWe present a facile and cost-effective manner to fabricate a highly sensitive and stable surface enhanced Raman scattering (SERS) substrate. First, a silicon nanowire array (SiNWA) is tailored by metal-assisted chemical etching (MaCE) method as a scaffold of the desired SERS substrate. Next, with an oblique angle deposition (OAD) method, optimized gold nanoparticles (AuNPs) are successfully decorated on the surface of the SiNWA. These AuNPs enable a strong localized electric field, providing abundant hot spots to intensify the Raman signals from the targeting molecules. By applying a well-established methodology, Taguchi method, which is invented for designing experiments, the optimized combination of parameters is obtained efficiently. The experimental results are also confirmed by finite-difference time-domain (FDTD) simulation calculations. Besides, a gold metal backplate (AuMBP) is applied to further enhancing the Raman signal intensity. Based on this developed SERS substrate, we demonstrated an enhancement factor (EF) of 1.78 × 106 and a coefficient of variation (CV) of 4.2%. Both EF and CV indicate a highly stable property and the optimized SERS substrate substantially outperform the commercial product. In the end, we also demonstrate a quantitative measurement on practical application of detecting malachite green (MG) with concentration from 10 nM to 100 μM.
Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction
Authors: Liu Chun-Shan , Yang-Yen Hsin-Fang , Suen Ching-Shu , Hwang Ming-Jing , Yen Jeffrey Jong-Young 
Published: June 2017

AbstractJAK2 activation is crucial for cytokine receptor signal transduction and leukemogenesis. However, the underlying processes that lead to full activation of JAK2 are unclear. Here, we report a positive role for ubiquitination of JAK2 during GM-CSF-induced activation. Upon GM-CSF stimulation, JAK2 ubiquitination is significantly enhanced through K63-linked poly-ubiquitination. Studies employing both knockout and overexpression of Cbl, an E3 ubiquitin ligase, led to the conclusion that Cbl specifically promotes JAK2 ubiquitination, and this was further confirmed in vitro using a Cbl ubiquitination assay. Moreover, following GM-CSF stimulation, the levels of phospho-JAK2 and -STAT5 and a STAT5 luciferase reporter assay were all reduced in Cbl knockout cells and this effect could be rescued by Cbl expression. Mechanistically, Cbl can interact with, and ubiquitinate JAK2 FERM and kinase domains via the Cbl TKB domain. Using lysine-to-arginine site-directed mutagenesis, K970 in the kinase domain of JAK2 was identified as the ubiquitination site important for promoting full JAK2 activation by Cbl via K63-conjugated poly-ubiquitination. Our study suggests that GM-CSF-induced JAK2 activation is enhanced by Cbl-mediated ubiquitination of JAK2. Targeting ubiquitination of JAK2 might offer a novel therapeutic strategy against JAK2-mediated disorders.
Detecting the Orbital Angular Momentum of Electro-Magnetic Waves Using Virtual Rotational Antenna
Authors: ZHANG Chao , MA Lu 
Published: June 2017

AbstractOrbital Angular Momentum (OAM) is a typical spatial mode of an Electro-Magnetic (EM) wave. Correctly detecting the OAM mode is fundamental and of foremost importance when applying the phenomenon to wireless transmission in free space. It is found that when rotating an OAM wave, a rotational Doppler shift that is proportional to the rotation speed and the OAM mode number can be observed. This property can be used for OAM detection, i.e., different OAM modes are identified by measuring the corresponding rotational Doppler frequency shifts. In previous work, this method was implemented by mechanically rotating the OAM wave, resulting in a small frequency shift. Since the high-speed mechanical rotation is hard to manufacture in a real system, it brings limitations to the bandwidth for each OAM wave. In this paper, we report on an OAM mode detection method based on digitally rotating a virtual antenna. The transmitter and receiver are physically fixed, but the Virtual Rotational Antenna (VRA) is obtained by interpolating the signals received from transverse-mounted receiving antennas. A large rotational Doppler shift occurs as a consequence of using digital processing, resulting in more capability for wideband wireless data transmission with the larger shifted frequency.
Decreased Estimated Glomerular Filtration Rate (eGFR), Not Proteinuria, Is Associated with Asymptomatic Intracranial Arterial Stenosis in Chinese General Population
Authors: Li Zhaoxia , Li Jinxin , Wang Anxin , Pan Hua , Wu Shouling , Zhao Xingquan 
Published: June 2017

AbstarctThe relationship between chronic kidney disease (CKD), which is defined by declined estimated glomerular filtration rate (eGFR) and/or proteinuria, and asymptomatic intracranial arterial stenosis (ICAS) is largely unknown. We conducted a population-based, cross-sectional study by recruiting 5209 participants free of previous stroke, transient ischemic attack and coronary heart disease. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula and proteinuria was estimated with urine dipstick. The presence of ICAS was assessed by transcranial color-coded Doppler (TCD). Out of the whole population, 684 (13.1%) participants suffered ICAS. After adjusting for the confounding factors, eGFR < 45 ml/min/m2 was an independent risk factor of asymptomatic ICAS (odds ratio [OR], 3.29, 95% confidence interval [CI], 1.67–6.51), but the trend was different between the two groups stratified by the age of 60 (P = 0.01). However, the association between proteinuria and asymptomatic ICAS was not statistically significant. In conclusion, declined eGFR, not proteinuria, is associated with asymptomatic ICAS in Chinese general population, especially in people over 60 years old.
Bi-2212/1T-TaS2 Van der Waals junctions: Interplay of proximity induced high-T

c
superconductivity and CDW order
Authors: Li Ang J. , Zhu Xiaochen , Stewart G. R. , Hebard Arthur F. 
Published: June 2017

AbstractUnderstanding the coexistence, competition and/or cooperation between superconductivity and charge density waves (CDWs) in the transition metal dichalcogenides (TMDs) is an elusive goal which, when realized, promises to reveal fundamental information on this important class of materials. Here, we use four-terminal current-voltage measurements to study the Van der Waals interface between freshly exfoliated flakes of the high-T
c
superconductor, Bi-2212, and the CDW-dominated TMD layered material, 1T-TaS2. For highly transparent barriers, there is a pronounced Andreev reflection feature providing evidence for proximity-induced high-T
c
superconductivity in 1T-TaS2 with a surprisingly large energy gap (~20 meV) equal to half that of intrinsic Bi-2212 (~40 meV). Our systematic study using conductance spectroscopy of junctions with different transparencies also reveals the presence of two separate boson modes, each associated with a “dip-hump” structure. We infer that the proximity-induced high-T
c
superconductivity in the 1T-TaS2 is driven by coupling to the metastable metallic phase coexisting within the Mott commensurate CDW (CCDW) phase and associated with a concomitant change of the CCDW order parameter in the interfacial region.
Transcranial random noise stimulation and cognitive training to improve learning and cognition of the atypically developing brain: A pilot study
Authors: Looi Chung Yen , Lim Jenny , Sella Francesco , Lolliot Simon , Duta Mihaela , Avramenko Alexander Alexandrovich , Cohen Kadosh Roi 
Published: June 2017

AbstractLearning disabilities that affect about 10% of human population are linked to atypical neurodevelopment, but predominantly treated by behavioural interventions. Behavioural interventions alone have shown little efficacy, indicating limited success in modulating neuroplasticity, especially in brains with neural atypicalities. Even in healthy adults, weeks of cognitive training alone led to inconsistent generalisable training gains, or “transfer effects” to non-trained materials. Meanwhile, transcranial random noise stimulation (tRNS), a painless and more direct neuromodulation method was shown to further promote cognitive training and transfer effects in healthy adults without harmful effects. It is unknown whether tRNS on the atypically developing brain might promote greater learning and transfer outcomes than training alone. Here, we show that tRNS over the bilateral dorsolateral prefrontal cortices (dlPFCs) improved learning and performance of children with mathematical learning disabilities (MLD) during arithmetic training compared to those who received sham (placebo) tRNS. Training gains correlated positively with improvement on a standardized mathematical diagnostic test, and this effect was strengthened by tRNS. These findings mirror those in healthy adults, and encourage replications using larger cohorts. Overall, this study offers insights into the concept of combining tRNS and cognitive training for improving learning and cognition of children with learning disabilities.
sRNA and cis-antisense sRNA identification in Staphylococcus aureus highlights an unusual sRNA gene cluster with one encoding a secreted peptide
Authors: Bronsard Julie , Pascreau Gaetan , Sassi Mohamed , Mauro Tony , Augagneur Yoann , Felden Brice 
Published: June 2017

AbstractThe human pathogen Staphylococcus aureus expresses a set of transcriptional factors and small RNAs (sRNAs) to adapt to environmental variations. Recent harmonization of staphylococcal sRNA data allowed us to search for novel sRNAs using DETR’PROK, a computational pipeline for identifying sRNA in prokaryotes. We performed RNA-Seq on Newman strain and identified a set of 48 sRNA candidates. To avoid bioinformatic artefacts, we applied a series of cut-offs and tested experimentally each selected intergenic region. This narrowed the field to 24 expressed sRNAs, of which 21 were new and designated with Srn identifiers. Further examination of these loci revealed that one exhibited an unusual condensed sRNA cluster of about 650 nucleotides. We determined the transcriptional start sites within this region and demonstrated the presence of three contiguous sRNA genes (srn_9342, srn_9344 and srn_9345) expressed from the positive strand, and two others (srn_9343 and srn_9346) transcribed from the opposite one. Using comparative genomics, we showed that genetic organization of the srn_9342-9346 locus is specific to Newman and that its expression is growth-phase dependent and subjected to nutrient deprivation and oxidative stress. Finally, we demonstrated that srn_9343 encodes a secreted peptide that could belong to a novel S. aureus toxin-antitoxin system.
Non-Darcy interfacial dynamics of air-water two-phase flow in rough fractures under drainage conditions
Authors: Chang Chun , Ju Yang , Xie Heping , Zhou Quanlin , Gao Feng 
Published: June 2017

AbstractTwo-phase flow interfacial dynamics in rough fractures is fundamental to understanding fluid transport in fractured media. The Haines jump of non-Darcy flow in porous media has been investigated at pore scales, but its fundamental processes in rough fractures remain unclear. In this study, the micron-scale Haines jump of the air-water interface in rough fractures was investigated under drainage conditions, with the air-water interface tracked using dyed water and an imaging system. The results indicate that the interfacial velocities represent significant Haines jumps when the meniscus passes from a narrow “throat” to a wide “body”, with jump velocities as high as five times the bulk drainage velocity. Locally, each velocity jump corresponds to a fracture aperture variation; statistically, the velocity variations follow an exponential function of the aperture variations at a length scale of ~100 µm to ~100 mm. This spatial-scale-invariant correlation may indicate that the high-speed local velocities during the Haines jump would not average out spatially for a bulk system. The results may help in understanding the origin of interface instabilities and the resulting non-uniform phase distribution, as well as the micron-scale essence of the spatial and temporal instability of two-phase flow in fractured media at the macroscopic scale.
Selective breeding and selection mapping using a novel wild-derived heterogeneous stock of mice revealed two closely-linked loci for tameness
Authors: Matsumoto Yuki , Goto Tatsuhiko , Nishino Jo , Nakaoka Hirofumi , Tanave Akira , Takano-Shimizu Toshiyuki , Mott Richard F. , Koide Tsuyoshi 
Published: June 2017

AbstractTameness is a major behavioral factor for domestication, and can be divided into two potential components: motivation to approach humans (active tameness) and reluctance to avoid humans (passive tameness). We identified genetic loci for active tameness through selective breeding, selection mapping, and association analysis. In previous work using laboratory and wild mouse strains, we found that laboratory strains were predominantly selected for passive tameness but not active tameness during their domestication. To identify genetic regions associated with active tameness, we applied selective breeding over 9 generations for contacting, a behavioural parameter strongly associated with active tameness. The prerequisite for successful selective breeding is high genetic variation in the target population, so we established and used a novel resource, wild-derived heterogeneous stock (WHS) mice from eight wild strains. The mice had genetic variations not present in other outbred mouse populations. Selective breeding of the WHS mice increased the contacting level through the generations. Selection mapping was applied to the selected population using a simulation based on a non-selection model and inferred haplotype data derived from single-nucleotide polymorphisms. We found a genomic signature for selection on chromosome 11 containing two closely linked loci.