bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between the Predictive Accuracy of Computed Tomography Severity Index and Clinical Metrics in Acute Pancreatitis at a Tertiary Care Hospital Lahore
Authors: Shams Fariha , Mushtaq Junaid , Siddique Smeera , Tayyab Ali Zayam , Malik Adeel Asghar , Adeel Muhammad , Rasool Shafqat , Haque Israr Ul , Tayyab Ghias Un Nabi 
Published: September 2024

Acute pancreatitis was a common clinical emergency and presents with a vast spectrum of severity and clinical outcomes. The Computed Tomography Severity Index (CTSI) was widely used to evaluate extent of pancreatic inflammation and necrosis. Objective: To compare the CTSI with the clinical severity of acute Pancreatitis in local settings. Methods: It was a retrospective cohort study done on 136 cases diagnosed with acute pancreatitis between 2017 to 2023 at Lahore General Hospital, Lahore, Pakistan. Patients received contrast-based Computed Tomography (CT) within 30 days of onset. CTSI scores were independently assessed by two experienced radiologists. Clinical severity was categorized as mild, moderate and severe pancreatitis. Statistical analysis was done with SPSS 26.0 which involved descriptive, correlational statistics, sensitivity and specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), predictive Accuracy along with ROC curve analysis and Cohen’s kappa statistic. Results: The patients were 74.3% males and had a median age of 51 years. CTSI demonstrated 79.37% sensitivity, 83.56% specificity, 80.65% PPV and 82.43% NPV in determining clinical severity as mild, moderate and severe with a predictive accuracy of 81.62%. Cohen’s kappa of 0.72 reflected substantial agreements between the CTSI and clinical severity assessment. Under the ROC Curve (AUC) the area was 0.87, showing an excellent diagnostic performance. Conclusion: CTSI provides a moderate to fair agreement with clinical severity assessments in acute pancreatitis. It effectively differentiates between mild, moderate and severe cases, supporting its assessment and management.
Analisis Wacana Kritis Perdebatan Dasar Negara Pada Sidang Konstituante: Sebuah Dinamika Dakwah Struktural
Authors: Indrawati Indrawati 
Published: September 2024

Pancasila selalu menjadi topik yang menarik untuk dikaji berkaitan karena keunikannya sebagai dasar negara yang dapat mempertemukan berbagai pihak/kelompok/golongan yang berbeda nilai-nilai, keyakinan dan kepentingannya. Setelah diterima sebagai dasar negara pada tanggal 1 Juni 1945, Pancasila dibahas kembali dalam sidang Konstituante untuk menetapkan dasar negara yang akan digunakan sebagai landasan hukum negara (undang-undang dasar) yang permanen. Fokus tulisan ini mengkaji bagaimana praktik wacana perdebatan dasar negara Pancasila-Islam yang berlangsung pada sidang Konstituante. Perspektif teori dan metode yang digunakan adalah metode analisis wacana kritis Fairclough, dengan tahapan analisis: analisis teks, analisis interpretasi dan analisis eksplanasi. Adapun kesimpulan yang didapatkan dari kajian ini antara lain: praktik wacana perdebatan dasar negara pada masa sidang konstituante yang dilancarkan oleh kubu kebangsaan menyimpan kepentingan mempertahankan dasar negara Pancasila mengingat Pancasila-lah yang mampu menjadi ideologi pemersatu dari semua golongan, sesuai dengan kepribadian bangsa Indonesia, sesuai dengan amanat revolusi Proklamasi 17 Agustus 1945, dan tidak mungkinnya Islam sebagai dasar negara karena hanya mewakili satu golongan. Sedangkan kubu Islam menolak dasar negara Pancasila adalah upaya memperjuangkan kembali dasar negara Islam setelah dihapusnya Piagam Jakarta serta adanya kekuatan atheisme yang bersembunyi di belakang Pancasila, yaitu PKI.
Perancangan Sistem Pakar Diagnosa Penyakit Depresi Pada Manusia Dengan Metode Certainty Factor
Authors: Suryadi Agus , Febrianti Eka Lia 
Published: September 2024

Tujuan penelitian adalah merancang dan membangun rekayasa perangkat lunak sistem pakar berbasis web yang mampu mendiagnosa penyakit depresi pada manusia untuk mendapatkan solusi dan informasi dengan mudah dan cepat. Penelitian ini menggunakan metode analisa nilai kepastian (Certainty Factor) berdasarkan jawaban atas pertanyaan yang diberikan oleh user. Hasil yang ditampilkan berupa kondisi user terkait dengan depresi. Hasil juga dilengkapi dengan penjelesan penyakit dan solusi pengobatan yang ditampilkan dalam bentuk website menggunakan pemrograman PHP dengan database MySQL. Kesimpulan dalam penelitian ini adalah bahasa pemograman PHP dan MySQL terbukti mampu diimplementasikan dalam merekayasa sistem pakar untuk mendiagnosa penyakit depresi.Metode Certainty Factor terbukti mampu melakukan penelusuran /pelacakan gejala penyakit depresi dengan mudah dan cepat dengan memberikan nilai kepastian.Sistem online dapat membantu user mendapatkan informasi tentang jenis-jenis penyakit, gejala dan solusi pengobatan pada penyakit depresi.
PENETAPAN STRATEGI PEMASARAN PRODUK KOKO KRUNCH DI KOTA BATAM
Authors: Setyabudhi Albertus Laurensius , Alamsyah Nanang , Cahyo Yayan Nur 
Published: September 2024

Tidak tercapainya target penjualan Produk Nestle Koko Krunch akan mempengaruhi kinerja dan peforma dari PT BIS sebagai distributor tunggal, Beberapa faktor yang menjadi penyebab tidak tercapainya target penjualan adalah Kurangnya Strategi pemasaran yang tepat untuk meningkatkan volume penjualan Produk Nestle Koko Krunch. Guna mengatasi permsalahan diatas maka perlu dilakukan suatu Analisa Strategi Pemasaran Produk Nestle Koko Krunch dengan Pendekatan SWOT-AHP (Analytic Herarchy Process) yaitu untuk mencari strategi alternatif yang paling tepat. Berdasarkan analisis internal dan eksternal perusahaan, faktor kunci internal yang merupakan kekuatan utama bagi PT. Bintang Intan Sarana yaitu Fasilitas,Peralatan,Armada dan Kantor dalam Kondisi Baik ( skor : 0.65). Sedangkan kelemahan utama perusahaan yaitu Reward Penjualan dan Mekanisme Kontrol, hal ini disebabkan mekanisme kontrol terhadap reward penjualan belum berjalan dengan efektif. Dari matriks IFE diperoleh total skor rata-rata sebesar 3.07 yang menunjukan perusahaan berada pada kondisi yang kuat. Faktor kunci eksternal yang merupakan peluang utama bagi PT. Bintang Intan Sarana yaitu produk koko krunch memiliki kesempatan untuk berinovasi (skor 0.44) karena citra merk yang baik selama ini di mata konsumen sehingga dapat dimanfaatkan oleh perusahaan untuk memaksimalkan penjualan produk nestle koko krunch. Sedangkan ancaman utama bagi perusahaan yaitu munculnya pesaing (skor : 0.26). Hal ini disebabkan karena batam adalah kota industri dengan mayoritas masyarakatnya pekerja sehingga tuntutan masyarakat terhadap semua kebutuhan yang cepat dan cenderung instan sudah menjadi gaya hidup, Makanan cepat saji adalah salah satu yang menjadi kebutuhan bagi masyarakat modern saat ini sehingga banyak produk sejenis yang bermunculan.
PERANCANGAN BANGUN APLIKASI DASHBOARD UNTUK MONITORING PRODUK BERBASIS WEB
Authors: Susilo Wawan 
Published: September 2024

Selain pemantauan persediaan barang, hal penting lain yang yang dibutuhkan dalam pengelolaan persediaan barang adalah pemantauan kondisi barang. Hal ini dibutuhkan agar barang yang digunakan untuk menunjang kegiatan operasional akan selalu dalam keadaan baik. Jika ditemukan adanya kondisi barang yang rusak, maka bisa dilakukan langkah penanganan baik itu dengan melakukan perbaikan atau melakukan pengadaan barang baru sebagai pengganti barang yang rusak, PT Mega Prima Perkasa yang berlokasi di Batam Center salah satu perusahaan di kota Batam yang bergerak sebagai bidang Supplier dan Distributor dimana untuk mengecek produk masih menggunakan form yang ditulis secara manual kemudian data tersebut dimasukan atau dikerjakan lagi menggunakan Microsoft Excel, hal ini tentu saja memiliki kesulitan tersendiri dalam melakukan pengecekan produk dan tidak efisien, sebagai perusahaan yang mempunyai banyak relasi dengan perusahaan lain maka dibutuhkan sebuah sistem untuk monitoring produk, monitoring sistem yang akan ditampilkan berbasis web dengan sistem dashboard).
Irradiação de luz azul de LED (460 nm) inibe formação de biofilme e não reduz a viabilidade de formas planctônicas de Pseudomonas aeruginosa
Authors: Gomes Victor Targino , Amaral Débora Conceição da Silva , Borchardt Hueliton , Vasconcelos Ulrich 
Published: September 2024

A utilização de métodos de controle microbiano alternativos é importante por impactar menos o ambiente. Este trabalho avaliou em o efeito do uso de luz azul antimicrobiana (aBL) com LED (460 nm) contra isolados selvagens de Pseudomonas aeruginosa. A capacidade de formar biofilme foi confirmada em caldo BHI e em seguida, o ensaio de injúria subletal expôs as células a 4 h de irradiação luminosa para verificar os efeitos sobre viabilidade celular séssil e planctônica de isolados selvagens de P. aeruginosa. Houve uma redução significativa da adesão das células, variando entre 86 e 99%. A adição de 0,1% de lactato, glutamato e sacarose ao meio agiu negativamente no rebrote de alguns isolados, diferente do observado com citrato 0,1 e 0,5%. Por outro lado, não foi verificada atividade antimicrobiana contra a população planctônica que reduziu apenas entre 4 e 24%, ao passo que aumentou as velocidades de flagelos e pili em até 9 vezes, e triplicou a produção de piocianina. Os resultados indicaram que o tratamento foi eficaz contra a formação do biofilme, mas não perturbou a viabilidade de células planctônicas.
O trabalho de campo na formação docente de geografia
Authors: Valença Mariana Rabêlo , Silva Helena Paula de Barros , Serafim Ana Regina Marinho Dantas Barboza da Rocha , Coutinho Solange Fernandes Soares , Andrade Gevson Silva , Oliveira Paulo César de , Silva Paulo Roberto Florêncio de Abreu e , Carvalho João Allyson Ribeiro de 
Published: September 2024

A geografia escolar, em geral, é trabalhada como uma simplificação da ciência geográfica, produzida e ensinada na academia, sem uma reflexão a partir da espacialidade vivida pelos estudantes. Não se considera seu conhecimento prévio, a realidade espacial na qual está inserido. Entende-seque uma abordagem interdisciplinar ancorada na realidade espacial da escola permite que a disciplina cumpra o seu papel de compreensão do espaço geográfico e exercício da cidadania. Para tanto, é necessário pensar a inicial que repercutirá diretamente na prática pedagógica na educação básica. Nesse sentido, este trabalho tem por objetivo discutir a importância do trabalho de campo, numa perspectiva interdisciplinar, na preparação de professores e professoras de geografia. Partiu-se do pressuposto de que com uma formação pautada na interdisciplinaridade que o campo possibilita, os professores da educação básica terão uma concepção da sua práxis pedagógica mais ampla, buscando sentido e articulação com o mundo real. Tais reflexões decorrem de experiências coletivas de aulas de campo, em turmas de licenciatura em geografia, da Universidade de Pernambuco, campus mata norte.
BARRIERS TO EMPOWER ADOLESCENTS IN PREVENTING PREMARITAL PREGNANCY: (QUALITATIVE STUDY IN CENTRAL JAVA PROVINCE, INDONESIA)
Authors: Shaluhiyah Zahroh , Kusumawati Aditya , Nugraha Priyadi , Indraswari Ratih 
Published: September 2024

Objective: Empowering adolescents with life skills to enable them to avoid unwanted pregnancies and sexually transmitted infections is urgently felt, but certain bottlenecks still persist in the path of making the adolescents responsible for their own sexual and reproductive health. This study aims to investigate the barriers that prevent teenagers from comprehending and taking charge of their sexual and reproductive well-being.

Material and Methods: Qualitative method was utilized, which included interviews with 35 teenagers from 20 villages and ten supervisors from five health facilities experiencing high levels of premarital pregnancies. Because of the COVID-19 outbreak, information was gathered through video conferences, and a thematic analysis was carried out utilizing Atlas.ti (version 8).

Results and Discussion: The pandemic impacted the behaviors of teenagers, leading to a decrease in premarital pregnancies among some due to fewer social interactions. Nonetheless, risky sexual behaviors continued due to insufficient sexual knowledge, cultural restrictions, and lack of communication among teenagers, parents, and teachers. The results emphasize the importance of thorough sexual education, better communication between parents and educators, and the active participation of teenagers in reproductive health programs. Enhancing life skills education in schools, backed by health centers and communities, is crucial in empowering adolescents to make educated decisions. Improved training for program managers is essential to guarantee the effectiveness of youth-friendly services.

Recommendation: Youth-friendly health services should include active adolescent participation to foster self-reliance and empowerment. Tailored approaches and engagement can improve adolescent health outcomes.
RELATO DE EXPERIÊNCIA: CURSO DE DISSECAÇÃO CADAVERICA PELA LIGA ARAGUAINENSE DE ANÁTOMO-FISIOLOGIA
Authors: Silva Nayane Bueno da , Barbosa Luíza Cristina Milhomem , Leite Lucas Monteiro , Galvão Rafaella Dias , Azevedo Anderson Luís Santos , Linhares Ketyla Albino , Godoi Flávio Júnior Soares , Silva Mário de Souza Lima e 
Published: September 2024

Introdução: Na formação médica, uma importante área de estudo é a anatomia humana, sendo a prática de dissecação uma ferramenta essencial para o aprendizado de acadêmicos. Objetivos: Com isso, objetiva-se relatar a experiência do curso de dissecação realizado por alunos de medicina do Centro Universitário Presidente Antônio Carlos (UNITPAC). Metodologia: Trata-se de um estudo descritivo e qualitativo, pela realização do curso de dissecação cadavérica pela Liga Araguainense de Anátamo-Fisiologia, ministrado pelo professor de anatomia no laboratório de anatomia do UNITPAC, nos dias 28/05 e 04/06 de 2022. Resultados: O curso iniciou-se com aprendizado teórico das habilidades de manuseio, posteriormente, a prática, exercendo a técnica de dissecar na casca de laranja para treinamento inicial e, após nas peças cadavéricas. Conclusão: Destarte, o curso alcançou o seu objetivo em favorecer o conhecimento e aprimoramento das habilidades exigidas na prática de dissecção cadavérica primordial no exercício médico.
In-Vitro Antifungal Efficacy of Salicylic Acid and Palm Oil on the Dermatophytic Fungus Causing Athlete’s Foot Disease
Authors: Mustapha Tijjani , Abdullahi Mai-Abba Ishiyaku , Kwarau Nathaniel Luka , Musa Hadiza Murtala , Kutama A S 
Published: September 2024

Study’s Excerpt/Novelty

This study investigates the antifungal properties of salicylic acid and palm oil against the dermatophytes responsible for infecting Athlete's foot.
By evaluating both the minimum inhibitory and fungicidal concentrations through in-vitro experiments, the research provides new insights into the potential use of these substances as alternative treatments.
The significant inhibitory effects observed, particularly for salicylic acid, highlight its stronger fungicidal properties, offering a promising alternative for future therapeutic applications in managing Tinea pedis.

Full Abstract

Athlete's foot, or Tinea pedis, is a widespread fungal infection primarily affecting the skin between the toes, caused by dermatophytes like Trichophyton rubrum and T. mentagrophytes. This study aimed to evaluate the in-vitro effects of salicylic acid and palm oil on dermatophytic fungus responsible for Athlete’s foot disease. Minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) were determined for salicylic acid and palm oil. The agar well diffusion method was used to measure the zone of inhibition at various concentrations (25%, 50%, 75%, and 100%) of both substances. The MIC was assessed using Sabouraud Dextrose Broth at concentrations of 3.12%, 6.25%, and 12.5%. Results indicated significant inhibitory effects of both salicylic acid and palm oil against the dermatophytes causing athlete's foot. The highest zone of inhibition was observed at 100% concentration for both substances: 5.50 mm for salicylic acid and 4.3 mm for palm oil. At 50% and 75% concentrations, the inhibition zones were 3.67 mm and 3.97 mm for salicylic acid and 2.20 mm and 3.00 mm for palm oil, respectively. The MIC for both substances was determined to be 3.12%, while the MFC was 3.12% for salicylic acid and 6.25% for palm oil, indicating stronger fungicidal properties for salicylic acid. Salicylic acid and palm oil show promise as agents against Tinea pedis. Further public health efforts are recommended to raise awareness about the prevention and transmission of the disease.
Cds Quantum Dots Composite Sol-gel Rod for Optical Applications
Authors: KHAN M. Naziruddin , ALMOHAMMEDI Abdullah 
Published: September 2024

Colloidal quantum dots (QDs) based on CdS were directly incorporated into a sol to fabricate solid rods. Various characterization techniques were employed to study the properties of the composite rod. A comparison between the absorption, emission, and excitation spectra of the QDs in the solid rod and in solution revealed their significant and stable nature in the solid state. SEM image shows that QD particles are well interacted with the sol gel environment. The observed particle size of QDs was heteronomous approximately from 5 to 10 nm. The XRD pattern of QDs illustrates their crystalline nature. The significant spontaneous emission (SE) signal was enhanced from QDs composite rod under the excitation of a 355 nm Pico second laser source. These findings suggest that further improvements in the integration of QDs into sol gel rods could be achieved by employing a higher density of QDs in the solid rod. The fabrication of QDs composite rods with a high concentration holds the potential for testing stimulated or amplified spontaneous emission in future studies.
Revision of the strongly flattened Megaprosternum Azevedo (Hymenoptera, Bethylidae)
Authors: Colombo Wesley D. , Azevedo Celso O. 
Published: September 2024

The flat wasp genus Megaprosternum (Scleroderminae) is studied and revised. Fifteen species are recognized, including five previously described ones: M. cleonarovorum, M. longiceps, M. neolongiceps, M. norfolcensis, and M. pentagonal. Additionally, 10 new species are described and illustrated: M. aka sp. nov. and M. bayaka sp. nov. (both from the Central African Rep.), M. chamorro sp. nov., M. hmong sp. nov., M. kariri sp. nov., M. kayin sp. nov., M. navatu sp. nov., M. nuaulu sp. nov., M. samburu sp. nov., and M. wakawaka sp. nov. An emended diagnosis and a detailed discussion regarding the morphological diagnostic characters of this genus and its species, along with comments about the distribution pattern of Megaprosternum, are also presented. Additionally, a taxonomic key for males and females of all species is provided.
The Anatomic Pathology Hospitalist Model
Authors: Chapel Ellen E. , Chapel David B. , Kunju L. Priya , Hamilton John A , Myers Jeffrey L. , Pantanowitz Liron 
Published: September 2024

Context.—
Challenges to staffing a high-quality frozen section service include consolidation of health systems and pathology practices, off-campus relocation of some pathology offices, growing numbers of stand-alone surgery centers, and subspecialization among pathologists and surgeons. To address these challenges, we developed a novel anatomic pathology hospitalist model with explicit emphasis in frozen section.

Objective.—
To evaluate our anatomic pathology hospitalist program’s impact on (1) frozen section staffing, (2) frozen-permanent diagnostic concordance, and (3) turnaround time.

Design.—
Frozen section staffing and performance data were collected for the 28-month period spanning July 1, 2021, to October 31, 2023. Outcomes were compared between hospitalists, nonhospitalists, and fellows.

Results.—
Hospitalists performed more frozen sections per month than nonhospitalists (median, 87 versus 17, respectively; P = .002). After implementation, nonhospitalists’ average frozen section staffing obligation fell from 3.7 (30%) of 12.3 total service days per month to 2.8 (22%) of 12.6 total service days per month (P = .005), compared with hospitalists’ average of 9.5 frozen section days (69%) of 13.7 total service days per month. Frozen-permanent concordance was marginally but significantly higher for hospitalists (4701 of 4744 blocks, 99.1%) than nonhospitalists (7259 of 7362 blocks, 98.6%; P = .02). Concordance did not correlate with pathologists’ academic rank or subspecialization. Turnaround times were comparable for hospitalists, nonhospitalists, and fellows across multiple metrics.

Conclusions.—
Our anatomic pathology hospitalists significantly reduced the frozen section obligations of nonhospitalist faculty, with a small but significant increase in frozen-permanent concordance and no substantial change in turnaround time.
Reduced Plasma Selenoprotein P Is Associated With Type I Antithrombin Deficiency and a Prothrombotic State
Authors: Klajmon Adrianna , Natorska Joanna , Corral Javier , de la Morena-Barrio Maria Eugenia , Bravo-Pérez Carlos , Kopytek Magdalena , Jankowska Urszula , Skupien-Rabian Bozena , Hanarz Maksymilian , Treliński Jacek , Ząbczyk Michał 
Published: September 2024

Context.—
A positive association between antithrombin activity and selenium level was reported. Selenoprotein P, the most important selenium carrier, was identified within human plasma fibrin clots.

Objective.—
To investigate the relationship between selenoprotein P and antithrombin and its role in modulation of fibrin clot properties in antithrombin-deficient patients.

Design.—
Proteomic analysis of plasma fibrin clots was performed with mass spectrometry. In 108 patients with genetically confirmed type I (57%) or type II (43%) antithrombin deficiency and in healthy controls (n = 50), we assessed plasma selenoprotein P levels and thiobarbituric acid–reactive substances by enzyme-linked immunosorbent assay, along with fibrin clot permeability, clot lysis time, and thrombin generation.

Results.—
Clot-bound antithrombin concentration was 0.46 ± 0.32 mg/g protein, while selenoprotein P level was 30-fold lower (0.015 ± 0.012 mg/g). Type I compared to type II antithrombin-deficient patients had higher clot-bound antithrombin and selenoprotein P levels (both P &lt; .001), associated together (ρ = 0.93, P &lt; .001). Individuals with type I compared to type II antithrombin deficiency or controls had about 40% lower plasma selenoprotein P levels (P &lt; .001). In antithrombin-deficient patients, plasma selenoprotein P was associated with antithrombin antigen (ρ = 0.35, P &lt; .001) and thiobarbituric acid–reactive substances (ρ = 0.42, P &lt; .001). Plasma selenoprotein P correlated also with endogenous thrombin potential (r = −0.33, P &lt; .001), fibrin clot permeability (r = 0.43, P &lt; .001), and clot lysis time (r = −0.40, P &lt; .001) in antithrombin-deficient patients but not in controls.

Conclusions.—
Patients with type I antithrombin deficiency had higher clot-bound selenoprotein P and reduced plasma selenoprotein P levels. Plasma selenoprotein P was associated with prothrombotic fibrin clot phenotype and enhanced thrombin generation.