bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives and Experiences on eHealth Solutions for Coping With Chronic Pain: Qualitative Study Among Older People Living With Chronic Pain
Authors: De Lucia Annalisa , Donisi Valeria , Pasini Ilenia , Polati Enrico , Del Piccolo Lidia , Schweiger Vittorio , Perlini Cinzia 
Published: September 2024

Background
Chronic noncancer pain (CNCP) is a major health issue among the older population, affecting multiple aspects of individual functioning. Recently, the use of eHealth solutions has been proposed in supporting chronic pain self-management even among older adults, although some barriers have emerged. Few qualitative studies, with none conducted in Mediterranean countries, have explored older people’s experiences and perceptions regarding the types of strategies used to cope with chronic pain and eHealth tools for chronic pain management.

Objective
This study’s objectives were to explore the perspectives and experiences of older adults regarding the coping strategies used to manage chronic pain, the use of digital technologies in everyday life, and the potentiality and barriers in using those technologies for health and pain management.

Methods
A multimethod approach (ie, self-report questionnaires and a semistructured interview) has been adopted targeting older adults (ie, those who are aged 65 to 80 years and presenting different types of CNCP) who are attending a pain therapy center in Italy. Qualitative answers were analyzed using thematic analysis.

Results
Overall, participants reported using a variety of pain coping strategies; however, they showed an attitude of resignation to their CNCP condition. Nearly 70% (12/18) of the interviewees referred to using digital technologies for purposes related to health and pain management, mostly involving very basic management activities. The participants’ opinions on the useful functions that need to be incorporated in eHealth tools for chronic pain management have been categorized into four themes: (1) specific pain self-management skills, (2) support in organizing various health-related aspects, (3) sharing experiences with others, and (4) increasing pain-related personal knowledge. Conversely, the following potential barriers to adopting eHealth tools emerged: (1) computer illiteracy, (2) negative effects or risks, (3) impersonal interaction, and (4) physical limitations.

Conclusions
The use of eHealth solutions still seems low, often being accompanied by a perceived lack of digital skills or attitude among a sample of older adults from Italy with CNCP. Before introducing innovative eHealth solutions, it would be of primary importance to take action to enhance, on the one hand, self-efficacy in pain management and, on the other, the digital literacy level among older people.
The Use of Mobile Health Care Among Medical Professionals in the Sichuan-Chongqing Region: Cross-Sectional Survey Study
Authors: Tang Yan , Yang Juan , Wang Ni , Wang Xin , Hu Wenli 
Published: September 2024

Abstract

Background
The emergence and integration of mobile health care technology have fundamentally transformed the health care industry, providing unprecedented opportunities to improve health care services and professional practice. Despite its immense potential, the adoption of mobile health care technology among health care professionals remains uneven, particularly in resource-limited regions.

Objective
This study aims to explore the use and influencing factors of mobile health care among health care professionals in the Sichuan-Chongqing region of China and make recommendations.

Methods
Convenience sampling was used in a cross-sectional study conducted from November 8 to November 14, 2023, to survey frontline clinical health care professionals at 5 district-level secondary public hospitals in the Sichuan-Chongqing region. A web-based questionnaire was used to investigate the use of mobile health care and its influencing factors among the participants. Descriptive analysis and logistic regression analysis were used in the study.

Results
A total of 550 valid questionnaires were completed. Among the surveyed health care professionals, only 18.7% (103/550) used mobile health care, with a satisfaction rate of only 50.5% (52/103). Around 81.3% (447/550) did not use any form of mobile health care. The age group of 30‐39 years was found to be a significant factor influencing the use of mobile health care by health care professionals (P=.03). The main reasons for not using mobile health care among health care professionals were lack of appropriate technical training and support (266/447, 59.5%), lack of suitable management-specific apps (204/447, 45.6%), and concerns about increased workload (180/447, 40.3%). There were significant differences in the single-factor analysis of the reasons for the nonuse of mobile health care among health care professionals from different specialties (P=.04). Logistic regression analysis indicated that age was the only significant factor influencing the use of mobile health care by health care professionals (P=.04).

Conclusions
The utilization rate of mobile health care among health care professionals in the Sichuan-Chongqing region is low. Age is a significant factor that influences whether health care professionals use mobile health care. Providing appropriate technical training and support may help improve the enthusiasm of health care professionals in using mobile health care.
Impact of Providing a Personalized Data Dashboard on Ecological Momentary Assessment Compliance Among College Students Who Use Substances: Pilot Microrandomized Trial
Authors: Linden-Carmichael Ashley , Stull Samuel W , Wang Danny , Bhandari Sandesh , Lanza Stephanie T 
Published: September 2024

Background
The landscape of substance use behavior among young adults has observed rapid changes over time. Intensive longitudinal designs are ideal for examining and intervening in substance use behavior in real time but rely on high participant compliance in the study protocol, representing a significant challenge for researchers.

Objective
This study aimed to evaluate the effect of including a personalized data dashboard (DD) in a text-based survey prompt on study compliance outcomes among college students participating in a 21-day ecological momentary assessment (EMA) study.

Methods
Participants (N=91; 61/91, 67% female and 84/91, 92% White) were college students who engaged in recent alcohol and cannabis use. Participants were randomized to either complete a 21-day EMA protocol with 4 prompts/d (EMA Group) or complete the same EMA protocol with 1 personalized message and a DD indicating multiple metrics of progress in the study, delivered at 1 randomly selected prompt/d (EMA+DD Group) via a microrandomized design. Study compliance, completion time, self-reported protocol experiences, and qualitative responses were assessed for both groups.

Results
Levels of compliance were similar across groups. Participants in the EMA+DD Group had overall faster completion times, with significant week-level differences in weeks 2 and 3 of the study (P=.047 and P=.03, respectively). Although nonsignificant, small-to-medium effect sizes were observed when comparing the groups in terms of compensation level (P=.08; Cohen w=0.19) and perceived burden (P=.09; Cohen d=-0.36). Qualitative findings revealed that EMA+DD participants perceived that seeing their progress facilitated engagement. Within the EMA+DD Group, providing a DD at the moment level did not significantly impact participants’ likelihood of completing the EMA or completion time at that particular prompt (all P>.05), with the exception of the first prompt of the day (P=.01 and P<.001).

Conclusions
Providing a DD may be useful to increase engagement, particularly for researchers aiming to assess health behaviors shortly after a survey prompt is deployed to participants’ mobile devices.

International Registered Report Identifier (IRRID)
RR2-10.2196/57664
Karakteristik Mutasi EGFR pada Pasien Kanker Paru Jenis Adenokarsinoma yang Diterapi dengan Tyrosien Kinase Inhibitor (TKI) di Rumah Sakit Paru Dr. H.A Rotinsulu Bandung
Authors: Puspita Desi , Dwi Astuti Vitri , Rina  , Sampurno Edi 
Published: September 2024

This descriptive study describes the proportion of Epidermal Growth Factor Receptor (EGFR) mutations in lung cancer Adenocarcinoma patients at Rumah Sakit Paru (RS Paru) Dr. H. A Rotinsulu Bandung in the range of 2018 to 2020.
EGFR mutations were examined using RGQ thera screen technology Real"‘Time Polymerase Chain Reaction from FFPE or cytology smear.
There are 44 data point mutations after examining the EGFR mutation. 59% cases were 40"‘60 years old group dan 52 % were female.
It was found that in this group 86% patient with single mutation and 16% had doube mutations. EGFR mutations occurred in Exon 21 L858R in 13 cases (30 %), Exon 21 L861Q in 1 case (2%), Exon 19del in 24 cases (55%), double mutation Exon 19 and Exon 20 T790M type in 2 cases (4%), double mutation Exon 19del and Exon 21 in 4 cases (9%).
Architectural Evolution of Administrative Buildings for the Lithuanian Municipalities During the Interwar Period
Authors: Vilkončius Evaldas 
Published: September 2024

Abstract
During the period of Lithuanian independence, which lasted from 1918 to 1940, various institutions operating in the country needed modern and suitable buildings. Thus, during the period of more than twenty years, numerous new public buildings were built for schools, hospitals, banks, and cultural institutions. In addition, there was a need to build new administrative buildings for the newly established county, city and township municipalities of the country, as there was a lack of suitable premises for them. Therefore, this article, presenting the most characteristic and typical examples, analyses the architectural evolution of the administrative buildings built for the Lithuanian municipalities during the period of independence.
Possibility of Renewable Energy Solutions Usage in Rural Areas of Western Balkans: Fuzzy-Rough Approach
Authors: Jeločnik Marko , Puška Adis , Nedeljković Miroslav , Božanić Darko , Subić Jonel 
Published: September 2024

Abstract
Energy production, supply and consumption are global issue with many economic, environmental and social implications. Mentioned issue is even more expressed in remote rural areas, in particular in developing countries, as are the countries of the Western Balkans (WB). Renewable energy sources (RES) could represent optimal energy alternative for sustainable performing of agricultural and other activities, as well as for improving the current state of living conditions in rural communities. The main goal of research is to mark the most suitable RES alternative (six alternatives) for wider implementation in rural space of WB. The applied methodology framework implies experts’ opinion (engagement of eight experts) and the use of multi-criteria decision-making methods (MCDM), (specifically fuzzy-rough LMWA and fuzzy-rough CRADIS methods) under the predefined criteria (nine criteria). Derived results show that the implementation of the solar energy plants could play an optimal solution, while as the relatively unsuitable alternative could be marked the use of energy potential of watercourses. Gained final result, i.e. ranking order of the considered alternatives is additionally verified by the appliance of other MCDM methods, while the sensitivity analysis was also performed.
Effect of Ozone on Enterobacteriaceae Counts in Wheat Grain, Alfalfa, Radish, Broccoli Seeds and Sprouts
Authors: Bernate Ilze , Sabovics Martins 
Published: September 2024

Abstract
The sprouts of various seeds have garnered considerable regard amid consumers due to its verdure, crispiness, and germination potential, offering a cost-effective and straightforward process. The moist and warm conditions are very conducive to germination, fostering the growth of microorganisms and thereby raising food safety concerns. The aim of the study was to investigate the impact of ozone on Enterobacteriaceae counts by subjecting wheat (Triticum aestivum) grains, alfalfa (Medicago sativa), radish (Raphanus sativus) and broccoli (Brassica oleracea) seeds to ozone gas treatment. Additionally, the grain and seeds were rinsed with ozonated water during germination. Three different treatment methods were employed for seeds and grains. In the first method, samples were exposed to ozone gas at 20 ppm for 10 minutes, with subsequent rinsing every 12 hours during germination until the rinse water appeared visually clean, at a concentration of 2.0 mg L−1 of ozone. The second method involved rinsing with ozonated water at a concentration of 2.0 mg L−1 for durations of 20, 40, and 60 minutes. The third method - treated with ozone gas at 50 ppm and the exposure time of 1, 2, 3, 4 and 5 h. Untreated samples were used as controls. Evaluation of the samples revealed that Enterobacteriaceae was virtually undetectable in dry seeds. However, after 72 hours of germination in both the control and ozone-treated sprouts and following 7 days of storage at 4±2 °C, Enterobacteriaceae were found at an average of 7 to 8.1 log CFU g−1 in all samples, irrespective of the treatment method. Additionally, mould was observed only in wheat and radish sprouts during the assessment period. The study showed that there was no significant reduction in the number of mesophilic aerobic and facultative anaerobic microorganisms, moulds and Enterobacteriaceae then treated with ozone gas.
Bridging Compassion and Commerce: Veterinarians’ Ethical Dilemmas in Providing Care for Homeless Animals
Authors: Šeiko Staņislavs , Možarova Aleksandra , Ņikišins Jurijs 
Published: September 2024

Abstract
This research seeks to expand the in-depth knowledge on the ethical dilemmas veterinary doctors face while providing care for homeless animals, brought to clinics by volunteers. Fifteen semi-structured interviews were conducted with veterinary doctors in Latvia. The study reveals the complex emotions involved in the interactions between veterinarians and volunteers, as well as the factors affecting a veterinarian’s decision made about homeless animals. The results show a positive attitude towards the altruism of volunteers, but significant concerns around financial matters and the use of animals for fundraising. Debates about charging for stray care highlight potential disagreements between veterinarians and activists. Veterinarians prioritise education and advocacy, providing compassionate assistance to pet owners. Societal expectations strongly shape how they perceive their role, emphasising the reduction of animal suffering and the improvement of animal welfare.
Algorithm for Determination of Pepper Maturity Classes by Combination of Color and Spectral Indices
Authors: Vasilev Miroslav , Shivacheva Galya , Stoykova Vanya , Zlatev Zlatin 
Published: September 2024

Abstract
The aim of the present work is to propose methods and tools for classifying sweet pepper into groups according to their degree of maturity based on color and spectral characteristics extracted from color images on the surface of the vegetables. The investigated pepper is two varieties of sweet - red Banji and yellow Liri. Five groups were formed, depending on the degree of maturity, and 16 color and 11 spectral indices were calculated for each of the groups. By successively using the ReliefF and PLSR methods, a selection of informative features and subsequent reduction of the vector formed by them was carried out, thereby aiming to increase the predictive results and minimize the time for data processing. The obtained classification errors between the individual stages of ripening vary according to the type of pepper and depending on which of the two types of maturity the fruits are in - technical or biological. For red sweet pepper, the separation inaccuracy obtained using a discriminant classifier with a quadratic separation function is in the range of 8 - 19%, while for yellow it is from 5 to 23%. The results obtained in the present work for the classification of pepper into groups according to their degree of maturity would support decision-making in selective harvesting and overall more accurate and efficient management of the harvesting process from the point of view of precision agriculture. The work will continue with studies related to the prediction of various compounds indicating changes in the color of peppers, including chlorophylls, carotenes and xanthophylls. In this way, it is possible to increase the accuracy in determining the degree of ripeness, since in pepper the color does not always follow the same pattern of change from green to yellow to orange to red.
Exploring Intestinal Permeability: Concept, Diagnosis, Connection to Bowel Disease, and Iron Deficiency
Authors: Basina Olesja , Derovs Aleksejs , Derova Jeļena , Lejniece Sandra 
Published: September 2024

Abstract
Over the recent years, intestinal permeability has become a major feature of gut health. The objective of this paper is to present a literature-based overview of the current understanding on intestinal permeability. The concept of intestinal permeability started its development from the discovery of tight junctions — protein complexes that are separated between the epithelial cells. Histopathology is the main option of microscopic diagnosis, which allows to determine changes that occur in the tight junction, inflammation, and damaged epithelial cells. Additionally, intestinal fatty acid-binding protein I-FABP and zonulin are suggested as biomarkers of epithelial barrier abruption. As for visual detection, literature proposes capsule endoscopy and confocal laser endomicroscopy. Using the latter it is possible to produce images of small intestinal morphology and visualise the small intestinal luminal elements, cells, villi as well as crypts. However, advancements in digital capsule endoscopy are more applicable and aid in research of intestinal permeability and enteropathy, also giving promising results in treatment. Although damage to intestinal permeability can be classified as a certain enteropathy and then the association of some enteropathies with iron deficiency already has been established, direct association of iron deficiency and intestinal permeability is yet to be explored.
Analysing Clinical And Demographic Data From A Study On Oral Lichen Planus Patients
Authors: Kakar Jagriti , Sokolovska Lība , Dabuzinskiene Anita , Murovska Modra , Čēma Ingrīda 
Published: September 2024

Abstract
Oral lichen planus (OLP) is a common mucocutaneous disorder affecting approximately 1–2% of the population, predominantly middle-aged women. This study aims to analyse the demographic and clinical characteristics of OLP patients treated at the Oral Medicine Centre of Institute of Stomatology, Rīga Stradiņš University. The cohort comprised adult patients diagnosed with OLP, who underwent structured clinical evaluations. The study identified significant patterns in age, gender distribution, clinical forms, and associated discomfort levels. Females constituted 75.76% of the cohort, with a mean age of 60 years. The reticular form of OLP was most prevalent, while the erosive form, associated with considerable discomfort, was more common in females. Treatment regimens varied, with Sol Kenalog 0.2% and Ointment Clobetasol 0.05% being the primary therapies. Sol Kenalog 0.2% was more effective in providing symptom relief and reducing relapse frequency. Chronic diseases and stress were prevalent among patients, complicating management and treatment outcomes. The study emphasises the need for personalised treatment strategies that consider the severity of the clinical form, patient comfort, and comorbid conditions. Further research is recommended to validate these findings and explore the underlying mechanisms of gender differences and the impact of comorbidities on OLP. The insights from this study aim to enhance clinical practices and improve patient outcomes.
Successful TAVI-in-TAVI for degenerated bioprosthetic aortic valve with severe stenosis-a case report
Authors: Apostu Alexandra , Deleanu Dan , Parasca Cătălina , Capșa Răzvan , Dobrovie Monica , Popescu Bogdan Alexandru , Chioncel Ovidiu , Iliescu Vlad Anton , Jurcuţ Ruxandra 
Published: September 2024

Abstract
Aortic stenosis is one of the leading causes of valvular disease requiring surgery or transcatheter intervention, with a rising prevalence due to the aging population. Current guidelines recommend transcatheter aortic valve implantation (TAVI) as the first-line treatment for patients with symptomatic severe aortic stenosis and high surgical risk. The indications for TAVI have expanded to low-surgical-risk patients due to increased operator experience and improved implanted devices with a dramatic reduction of complications. Considering the limited durability of bioprostheses, TAVI-in-TAVI procedures have been successfully performed as an alternative to surgery.
We present the case of an elderly patient who underwent a successful TAVI-in-TAVI for a degenerated bioprosthetic valve with severe stenosis. Multimodal imaging, including transthoracic echocardiography, transesophageal echocardiography, and cardiac computed tomography, played a crucial role in demonstrating the degeneration of the aortic bioprosthetic valve with severe stenosis. Excellent short- and long-term results were achieved by reducing transaortic gradients and improving the functional NYHA class.
This case highlights the importance of proper patient selection using multimodality imaging and suggests the need for TAVI-in-TAVI to become an available and safe option for the management of a failed bioprosthesis valve.
The Rule of Law Threatened by Environmental Governance: A Reading Applied to Environmental Policy of Minas Gerais
Authors: Padovani Vinicius Papatella , Ribeiro Gabriel Costa 
Published: September 2024

Purpose: This article recalls and analyzes social events that took place between 2012 and 2017 and that marked the daily life of environmental policy in the state of Minas Gerais.

Theoretical Framework: Identified with the critical construction of Political Ecology and collated with empirical elements, it explores the notions of field and environmental injustice to argue that the logic of Environmental Governance in Minas Gerais constituted a threat to the Rule of Law.

Design/Methodology/Approach: The methodological procedures consist of bibliographical and documentary research, as well as direct observation of thematic events held at the time.
Findings: To support the hypothesis, the foundations of the Environmental Rule of Law are presented, and then it is argued how the main existing territorial-environmental management instruments, as a rule, have contributed to the constitution of an Environmental Rule of Law of appearance.

Implications: The focus is on Latin American methodologies and research that map conflicts and communicate them on the World Wide Web, allowing free access to details of the environmental conflicts identified, from a perspective that raises issues of our time and place.